LOCUS       DAVHTH010000001       102813 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.001, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000001 DAVHTH010000000
VERSION     DAVHTH010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 102813)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 102813)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..102813
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.001"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            64..720
                     /locus_tag="VVR63_000001"
     CDS             64..720
                     /locus_tag="VVR63_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HEU6128070.1"
                     /translation="MPTALGYVSIGLACGIIGAPYVTPVEMGLMSLFVYAGSAQFAML
                     ALIVVQAPVAAIAMTVFLINLRLFLLSLHASTYFRHTSLWHNIGMSSILTDETYGVLM
                     GELAHTDKVNPMWMHGNNLNSYVAWFVGTVVGTALGDLLPNPEIFGLDFALVGMFIGI
                     FASQFQMMQRRISVRNLLIILAVVAVSFFLLLTVVSQSLAVLFATLLGCSMGMVLDGQ
                     "
     gene            710..919
                     /locus_tag="VVR63_000002"
     CDS             710..919
                     /locus_tag="VVR63_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000253940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HEU6128071.1"
                     /translation="MVSKYLLLAVIFSGLVTWIPRMIPFILVKYKGLPTIVERFLKFL
                     PVSIIFALILSRVVTGKVGNLPQIK"
     gene            1137..1967
                     /locus_tag="VVR63_000003"
     CDS             1137..1967
                     /locus_tag="VVR63_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU6128072.1"
                     /translation="MKKIVKYSSLAALALVAAGVLAACSGGAKKEGQAASKKEIIVAT
                     NGSPRPFIYEENGELTGYEIEVVRAIFKDSDKYDVKFEKTEWSGVFAGLDADRYNMAV
                     NNLSYTKERAEKYLYAAPIAQNPNVLVVKKDDSSIKSLDDIGGKSTEVVQATTSAKQL
                     EAYNAEHTDNPTILNYTKADFQQIMVRLSDGQFDYKIFDKIGVETVIKNQGLDNLKVI
                     ELPSDQQPYVYPLLAQGQDELKSFVDKRIKELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            2121..2975
                     /locus_tag="VVR63_000004"
     CDS             2121..2975
                     /locus_tag="VVR63_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HEU6128073.1"
                     /translation="MKIKKWLGLVALATVAGLALAACGNSEKKADNATTIKIATVNRS
                     GSEEKRWDKIQELVKKDGITLEFTEFTDYSQPNKATADGEVDLNAFQHYNFLNNWNKE
                     NGKDLVAIADTYISPIRLYSGLNGSANKYTKVEDIPANGEIAVPNDATNESRALYLLQ
                     SAGLIKLDVSGTALATVANIKENPKNLKITELDASQTARSLSSVDAAVVNNTFVTEAK
                     LDYKKALFKEQADENSKQWYNIIVAKKDWETSPKADAIKKVIAAYHTDDVKKVIEESS
                     DGLDQPVW"
     gene            3075..4448
                     /locus_tag="VVR63_000005"
     CDS             3075..4448
                     /locus_tag="VVR63_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HEU6128074.1"
                     /translation="MVFPSEQEQIEKFEKDHVAQHYFEVLRTLISKKSVFAQQVGLKE
                     VANYLGEIFKRVGAEVEIDESYTAPFVMAHFKSSRPDAKTLIFYNHYDTVPADGDQVW
                     TEDPFTLSVRNGFMYGRGVDDDKGHITARLSALRKYMQHHDDLPVNISFIMEGAEESA
                     STDLDKYLEKHADKLRGADLLVWEQGTKNALEQLEISGGNKGIVTFDAKVKSADVDIH
                     SSYGGVVESAPWYLLQALQSLRAADGRILVEGLYEEVQEPNEREMALLETYGQRNPEE
                     VSRIYGLELPLLQEERMAFLKRFFFDPALNIEGIQSGYQGQGVKTILPAEASAKLEVR
                     LVPGLEPHDVLEKIRKQLDKNGFDKVELYYTLGEMSYRSDMSAPAILNVIELAKKFYP
                     QGVSVLPTTAGTGPMHTVFDALEVPMVAFGLGNANSRDHGGDENVRIADYYTHIELVE
                     ELIRSYE"
     gene            4441..5502
                     /locus_tag="VVR63_000006"
     CDS             4441..5502
                     /locus_tag="VVR63_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HEU6128075.1"
                     /translation="MSRDIIKLDQIDVTFHQKKRTITAVKDVTIHIQEGDIYGIVGYS
                     GAGKSTLVRVINLLQKPSAGKITIDDDVIFDGKVTLTAEQLRRKRQDIGMIFQHFNLM
                     SQKTAEENVAFALKHSGLSKEEKKAKVAKLLDLVGLADRAENYPSQLSGGQKQRVAIA
                     RALANDPKILISDESTSALDPKTTKQILALLQDLNQKLGLTVVLITHEMQIVKDIANR
                     VAVMQDGHLIEEGSVLEIFSNPKQPLTQDFISTATGIDEAMVKIEKQEIVEHLSENSL
                     LVQLKYAGASTDEPLLNELYKHYQVMANILYGNIEILDGTPVGELVVVLSGEKAALAG
                     AQEAIRQAGVQLKVLKGVQ"
     gene            5504..6196
                     /locus_tag="VVR63_000007"
     CDS             5504..6196
                     /locus_tag="VVR63_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6128076.1"
                     /translation="MESLIQTYLPNVYKMGWAGQAGWGTAIYLTLYMTVLSFIIGGFL
                     GLVAGLFLVLTAPGGVLENKVVFWILDKITSIFRAVPFIILLAILSPLSHLIVKTSIG
                     PNAALVPLSFAVFAFFARQVQVVLAELDGGVIEAAQASGATFWDIVGVYLSEGLPDLI
                     RVTTVTLISLVGETAMAGAVGAGGIGNVAIAYGFNRYNHDVTILATIIIILIIFAIQF
                     LGDFLTKKLSHK"
     gene            complement(6226..6795)
                     /locus_tag="VVR63_000008"
     CDS             complement(6226..6795)
                     /locus_tag="VVR63_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEU6128077.1"
                     /translation="MKKSILTTLLFAVLYFLCMGIGVLLGNLFDQTGNMFYAPAFTAL
                     VGGSVYMILVAKVPRFGAITTIGLVIALFFLGTKHGAGSFLPGIICGLLADEVAHLGK
                     YKDKTKNFLSFIIFAFSTTGPILLMWIAPKAYMATLLARGKSQEYIDRIMVAPNPGTV
                     LLFIASIVIGALVGALIGQALSKKFAQKI"
     gene            6930..7544
                     /locus_tag="VVR63_000009"
     CDS             6930..7544
                     /locus_tag="VVR63_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000532354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEU6128078.1"
                     /translation="MGRFLDFVFNRFFLGMIATAFFWLLTLAGGIILGLAPASATLMS
                     LYAEHGYSFREYSLKEAWSLYKQNFVSSNLIFYSFLGVGLVLTYGLYLLVQLPHQTIV
                     HLIATLLNVLVVALIFLAYTVSLKLQVYFALSYRNSLKLSLIGIFMSLAAVAKILLGT
                     VLLVAIGYYMPALLFFVGIGMWHFFISDMLEPVYEIIHEKLATK"
     gene            7546..9192
                     /locus_tag="VVR63_000010"
     CDS             7546..9192
                     /locus_tag="VVR63_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU6128079.1"
                     /translation="MKQFWLHTLLRTYSSVMIIIIASFAILLSYADWDSREKEAQRVA
                     QRVTARTVSEIEYYHRESTQIAQALVENQARIEGIYKYFSLSMPDYFYWQLERKASPY
                     ISVSLYENVDDLYVRNDFVTGVAIAFQDYKEVYVSTKDKRSGEKIRAEDFKPAGNSFA
                     IPVSDPVSDQDLGVIYISLDPAVLYHAIDNTRGHTPMAVTVTSPFDTEIFHIGETVDK
                     ESENWLVGLTSHGYQVQVAVPKNFVLQGTVTSSALIVGLSLLFIVILYLTLRQTFANY
                     QKQVVDLVESIQVIAQGEEGRRIDISEKDQELLLIAETTNDMLDRLEKNIHDIYQLEL
                     SQKDANMRALQAQINPHFMYNTLEFLRMYAVMQSQDELADIIYEFSSLLRNNISDERE
                     TLLKQELEFCRKYSYLCMVRYPKSIAYGFKIDPELENMKIPKFTLQPLVENYFAHGVD
                     HRRTDNVISIKALKQDGFVEILVVDNGRGMSAEKLANIREKLSQRYFEHQASYSDQRQ
                     SIGIVNVHERFVLYFGDRYAITIESAEQAGVQYRITIQDE"
     gene            9204..10490
                     /locus_tag="VVR63_000011"
     CDS             9204..10490
                     /locus_tag="VVR63_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU6128080.1"
                     /translation="MYKVLLVDDEYMVTEGLKRLIPFDKWDMEVVATVSHADEALEYV
                     QENPVDVIISDVNMPDKTGLDMIREMKEILPDAAYILLSGYQEFDYVKRAMNLSVVDY
                     LVKPVDKVELGNLLEKIAGQLGERGKKSQTLSQELDEAGFVSYLGDKENWWIGLSKEK
                     QGSFTIPYYVLGQDWQIFISDQPLDGLVVTPFEAPYQEHFERWKLNAEKTLFYGSVNL
                     QQSESLFAYYEPIYRVIIQGNLNQIVEELNLLEKVVLENTPRVPITKQLFIQFVMDVF
                     HLFEHLKADDLTDIVKTIHAIQSFDELVPYIKETLTSFFGQYRMNENVVSVLEVIGRD
                     YQKELSLKDISKDLFINPVYLGQLIKRETDSTFAELLNKQRIKAAQQLLLSTSDSIED
                     ICYAVGYSNLGYFYKVFRKLCGKSPKAYRKQVETIL"
     gene            10551..11084
                     /locus_tag="VVR63_000012"
     CDS             10551..11084
                     /locus_tag="VVR63_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000729030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6128081.1"
                     /translation="MKKKPIYLWVLLILSALISVPSLFGIVSPLPSKEALRTAQKQVA
                     GVNAQQLEDQLNYTYRVAEASHSIFNVALIVLSTILVVVAIVFLVRKNLQYANYTYVG
                     YVLLAIIGSIYGYVGLQDAVQLVQDESMRLTVSIGSKAVSIFYIVINVLFLALVFYKM
                     WRQQKALAEEEETEELT"
     gene            11162..11632
                     /gene="nrdI"
                     /locus_tag="VVR63_000013"
     CDS             11162..11632
                     /gene="nrdI"
                     /locus_tag="VVR63_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEU6128082.1"
                     /translation="MKTISLVYISLSGNTESFVTRLKDYLLSQYKGIEVQKIHIKDLV
                     KEGKNFYEMDHPYVAFLPTYLEGGNGVDNGDVEILTTPVGDFIAYGNNASKCFGVVGS
                     GNRNFNNQYCLTAKQYSQRFGFPVLADFEMRGMLEDIKHVAAIIADLYELEKEN"
     gene            complement(11925..13187)
                     /locus_tag="VVR63_000014"
     CDS             complement(11925..13187)
                     /locus_tag="VVR63_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000075801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HEU6128083.1"
                     /translation="MSQAISLNQSTWASKLKAMGPGILMATAAVGGSHIVSSTQAGGS
                     YGWSLLLLVILANVFKYPFFRFGAEYTADTGKTLVEGYAEKGKLYLWIFFILNVFSAM
                     VNTAGVAILCSAIIASAFPMIGLSITQWSLILVAIIWAMLLFGGYKLLDGMVKWIMSA
                     LTIATVLAVIIAAVKHPEYSSDFVEKTPWQMAALPFIVSLLGWMPAPIEISAINSLWS
                     AEKRKTVNFNTEDALFDFNTGYIGTAILAVFFVALGALIQYPTGQAVEAASAKYISQF
                     VGMYASVLGEWSRYLITFIAFLCIFGTVITVIDGYSRVNQESLRLLISQKEDNRKSLN
                     IWMTITAIIGIVIIKFFAGQVSTMLRFAMIGSFLTTPFFALLNYALVTRENKNLPSWL
                     KHLAIAGLIFLFGFAIFFIYALAIGKAG"
     gene            complement(13497..13955)
                     /locus_tag="VVR63_000015"
     CDS             complement(13497..13955)
                     /locus_tag="VVR63_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3021 domain-containing protein"
                     /protein_id="HEU6128084.1"
                     /translation="MKKQVFHDAAAGVLIGLILSILFSLIYAPNTYAPLNPYSLIGQV
                     MDQHQVHGALVLLYCTLIWAAIGMLFNFGNRLFSRDWSMLRATLTHFFLMLAGFVPLA
                     TLAGWFPFHWIFYLQLIIEFAIVYLIIWAILYKREAKKVDHINQLLEHRK"
     gene            complement(13952..14392)
                     /locus_tag="VVR63_000016"
     CDS             complement(13952..14392)
                     /locus_tag="VVR63_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU6128085.1"
                     /translation="MKVELQISETYEEEKLIVQAPQETEKVQKVIEFAENLDQREKIK
                     GKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSIDLRLYQVLKLLPSNFIQISQSE
                     IINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL"
     gene            14748..16697
                     /gene="mutL"
                     /locus_tag="VVR63_000017"
     CDS             14748..16697
                     /gene="mutL"
                     /locus_tag="VVR63_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HEU6128086.1"
                     /translation="MSHIIELPEMLANQIAAGEVIERPASVVKELVENAIDAGSSQII
                     IEIEEAGLKKVQITDNGHGIAHDEVELALRRHATSKIKNQADLFRIRTLGFRGEALPS
                     IASVSVLTLLTAVDGASHGTKLVARGGEVEEVIPATSPVGTKVCVEDLFFNTPARLKY
                     MKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLVSA
                     KKMIEIENSDLDFEISGFVSLPELTRANRNYISLFINGRYIKNFLLNRAILDGFGSKL
                     MVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKEKELMTLVSEAIANSLKEQTLIPD
                     ALENLAKSTVRNREKVEQTILPLKENTLYYEKTEPSRPSQTEVADYQVELTDEGQDLT
                     LFAKETLDRLTKPAKLHFAERKPANYDQLDHPELDLASIDKAYDKLEREEASSFPELE
                     FFGQMHGTYLFAQGRDGLYIIDQHAAQERVKYEEYRESIGNVDQSQQQLLVPYIFEFP
                     ADDALRLKERMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCDMLLLTK
                     EVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSQCDNPYNCPHGRPVLVHF
                     TKSDMEKMFRRIQENHTSLRELGKY"
     gene            complement(17022..17489)
                     /locus_tag="VVR63_000018"
     CDS             complement(17022..17489)
                     /locus_tag="VVR63_000018"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HEU6128087.1"
                     /translation="MNTYEGNLVANNIKIGIVVARFNEFITSKLLSGALDNLKRENVN
                     EKDIEVAWVPGAFEIPLIASKMAKSKKYDAIICLGAVIRGNTSHYDYVCSEVSKGIAQ
                     ISLNSEIPVMFGVLTTDTIEQAIERAGTKAGNKGSECAQGAIEMVNLIRTLDA"
     gene            complement(17490..18695)
                     /locus_tag="VVR63_000019"
     CDS             complement(17490..18695)
                     /locus_tag="VVR63_000019"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HEU6128088.1"
                     /translation="MEYRKIQEALEALQKGRLVLVIDDKDRENEGDLICSAQAATTEN
                     VNFMATYAKGLICMPMSESLANQLMLSPMVENNTDNHKTAFTVSIDYKETTTGISAEE
                     RGLTARMCVAEDITPSDFRRPGHMFPLIAKKGGVLERNGHTEATVDLLKLAGLKECGL
                     CCEIMNHDGKMMRTDDLIQFSKKHNIPLITIKELQEYRKVYDQLVERVSTVNMPTRYG
                     NFKAISYIDKLNGEHHLALIMGNIEDEANVLCRVHSECLTGDVLGSLRCDCGQQFDKA
                     MKMIVENGSGVLLYLRQEGRGIGLINKLKAYHLQDQGMDTLDANLALGFEGDLREYHI
                     GAQMLKDLGLQSLHLLTNNPDKVEQLEKYGITISSRISIEIEANPYDSFYLETKKNRM
                     GHILNMEEK"
     gene            complement(18715..19350)
                     /gene="ribE"
                     /locus_tag="VVR63_000020"
     CDS             complement(18715..19350)
                     /gene="ribE"
                     /locus_tag="VVR63_000020"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HEU6128089.1"
                     /translation="MFTGIIEEIGKVERIQKDSRNCKLSIKASKILTDIHLGDSIAVN
                     GICLTVTHFNHQSFTVDVMNETWSRTALTLLKHGSEVNLERALSVNGRLGGHVVTGHI
                     DGTGKISSIKKDDNAVWYQINTQKEILDLIVEKGSITIDGISLTVAKVSKVNFSVSVI
                     PHTLEQTILKSKQVGNTVNLENDILGKYVQKLMDNSPKSEISKELLYQNGF"
     gene            complement(19335..20435)
                     /gene="ribD"
                     /locus_tag="VVR63_000021"
     CDS             complement(19335..20435)
                     /gene="ribD"
                     /locus_tag="VVR63_000021"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HEU6128090.1"
                     /translation="MSDSKYMKLAIKLAQKGAGYVNPNPMVGAVIVKDNHIIGQGYHE
                     FFGGPHAERNALKNCRESPVGATLYVTLEPCCHFGKTPPCIDAIIDSGITRVVIGSLD
                     CNPIVSGKGVKILEENNLQVTVGILENECLNLIKSFRKYITQHVPYVFMKYAMSMDGK
                     IATKTNQSKWITEEEARKHVHQLRHHVSAIMVGVNTVIQDDPLLTCRLEERKNPIRII
                     CDTHLRTPLTSKIVKTANDIKTYIATSSEDKNKMKLYQNHGCEILSIKKKGNHIDLSS
                     LMQHLGNMQIDSLVLEGGSLMNWSALEQQIVDELKIYIAPKIFGGSAKFPVGGEGISL
                     PNDAIRLKPYAFSQIGNDYLIESEVIYPCSQE"
     regulatory      complement(20569..20683)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            20840..21433
                     /gene="ruvA"
                     /locus_tag="VVR63_000022"
     CDS             20840..21433
                     /gene="ruvA"
                     /locus_tag="VVR63_000022"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HEU6128091.1"
                     /translation="MYAYLKGIITKITAKYIVLETNGIGYILHVANPYAYSGQVNQEA
                     QIYVHQVVREDAHLLYGFRSEDEKKLFLSLISVSGIGPVSALAIIAADDNAGLVQAIE
                     TKNITYLTKFPKIGKKTAQQMVLDLEGKVVVAGDGLPAKVAVQASAENQELEEAMEAM
                     LALGYKATELKKIKKFFEGTTDTAENYIKSALKMLVK"
     gene            21443..22006
                     /locus_tag="VVR63_000023"
     CDS             21443..22006
                     /locus_tag="VVR63_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HEU6128092.1"
                     /translation="MTKRCSWVKMTNPLYIAYHDEEWGQPLHDDQALFELLCMETYQA
                     GLSWETVLNKRQAFREAFYGYQIQAVAEMTDTELEALLENPAIIRNRAKIFATRANAQ
                     AFLRLQEEYGSFDAYLWSFVEGKIVVNDVPDYRQAPAKTPLSEKLAKDLKKRGFKFTG
                     PVAVLSFLQAAGLVDDHENDCEWKGLK"
     gene            22003..22680
                     /locus_tag="VVR63_000024"
     CDS             22003..22680
                     /locus_tag="VVR63_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000987430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU6128093.1"
                     /translation="MMSNKNKGILIFAILYTVLFVFDGVKLLASLMPSVIANYLVYVV
                     LALYGSFLFKDRLIQQWKEIRKTKRKFFFGVLTGWLFLILMTVVFEFVSEMLKQFVRL
                     DGQGLNQSNIQSTFQEQPLLIAVFACVIGPLVEELFFRQVLLHYLQERLPGLLSIILV
                     GLVFALTHMHSLALSEWIGAVGYLGGGLAFSIIYVKEKENIYYPLLVHMLSNSLSLII
                     LAISIVK"
     gene            complement(22817..23848)
                     /locus_tag="VVR63_000025"
     CDS             complement(22817..23848)
                     /locus_tag="VVR63_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HEU6128094.1"
                     /translation="MVSTIGIVSLSSGIIGEDFVKHEVDLGIQRLKDLGLNPIFLPHS
                     LKGLDFIKDHPEARAEDLIHAFSDDSIDMILCAISGDDTYRLLPYLFENDQLQKVIKQ
                     KIFLGFSDTTMNHLMLHKLGIKTFYGQSFLADICELDKEMLAYSLHYFKELIETGRIS
                     EIRPSDVWYEERTDFSPTALGTPRVSHTNTGFDLLQGSAQFEGKILGGCLESLYDIFD
                     NSRYADSTELCQKYKLFPDLSDWEGKILLLETSEEKPKPEDFKKMLLTLKDTGIFAVI
                     NGLLVGKPMDETFHDDYKEALLDIIDSNIPIVYNLNVGHATPRAIVPFGVHAHVDAQE
                     QVILFDYNK"
     gene            complement(24103..24786)
                     /locus_tag="VVR63_000026"
     CDS             complement(24103..24786)
                     /locus_tag="VVR63_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HEU6128095.1"
                     /translation="MSQIDLQKLTKKNQEFVHIATQQFIKDGKTDAEIQTIFEEVIPQ
                     ILEEQSKGTTARSLYGAPTHWAHSFTVKEQYEKEHPKENDDPKLMIMDSALFITSLFA
                     LVSALTTFFAADQAFGYGLITLLLVGLVGGFAFYLMYYFVYQYYGPDMDRSQRPPFWK
                     SVLVILTSMFLWLLVFFATSFLPASLNPVLDPLPLAIIGVALLALRFYLKKRLNIRSA
                     SAGPTRYQE"
     gene            complement(24798..25742)
                     /locus_tag="VVR63_000027"
     CDS             complement(24798..25742)
                     /locus_tag="VVR63_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEU6128096.1"
                     /translation="MKQVFLSTTTEFKEIDTLEPGTWINLVNPTQNESLEIANTFDID
                     IADLRAPLDAEEMSRITIEDEYTLIIVDVPVTEERNNRTYYVTIPLGIIITEETIITT
                     CLEPLPVLDVFINRRLRNFYTFMRSRFIFQILYRNAELYLTALRSIDRKSEQIESQLH
                     QSTRNEELIELMELEKTIVYFKASLKTNERVIKKLTSSTSNIKKYLEDEDLLEDTLIE
                     TQQAIEMADIYGNVLHSMTETFASIISNNQNNIMKTLALVTIVMSIPTMVFSAYGMNF
                     KDNEIPLNGEPNAFWLIVFIAFAMSVSLTLYLIHKKWF"
     gene            25874..28705
                     /gene="uvrA"
                     /locus_tag="VVR63_000028"
     CDS             25874..28705
                     /gene="uvrA"
                     /locus_tag="VVR63_000028"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HEU6128097.1"
                     /translation="MQDKIVIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TLYAEGQRRYVESLSAYARQFLGNMEKPDVDAIDGLSPAISIDQKTTSKNPRSTVGTT
                     TEINDYLRLLYARVGTPYCINGHGAINASSVEQIVDKVLELPERQRLQILAPVIRKKK
                     GQHKSVIEKVQKDGYVRVRVDGEVYDVTEVPELSKSKQHNIDVVVDRIVIKEGIRSRL
                     FDSIEAALRIAEGYVIIDTMDDSELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCS
                     ECDGLGIKLEVDTDLVVPDASKTLHEGALAPWNPISSNYYPNMLEQAMKVFGVAMDKP
                     FEDLSEEDKNLILYGSDGKEFHFHYENEFGGVRDIDIPFEGVINNIKRRYHETNSDYT
                     RTQMRLYMNELTCGTCQGYRLNDQALSVRVGGQQGPHIGEISDLSIADHLDLVSQLTL
                     SENEAIIARPILKEIKDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLIDVGPGA
                     GVFGGEIVAAGTPKQVARNSKSITGQYLSGKRVIPVPEERRVGNGRFIEVTGARENNL
                     QNVTARFPLGKFIAVTGVSGSGKSTLINSILKKAIAQKLNRNSDKPGKFKTITGIEHV
                     DRLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVACEVCHGTRYNSETLEVHYKEKNISQVLDMTVNDAVE
                     FFQHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYIL
                     DEPTTGLHTEDIARLLKVLARFVDAGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGT
                     IIVTGTPEEVAANEASYTGHYLKGKLHHE"
     gene            28698..29759
                     /locus_tag="VVR63_000029"
     CDS             28698..29759
                     /locus_tag="VVR63_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEU6128098.1"
                     /translation="MNKRVQAFLAKMQEKELDGIIINNLKNVYYLTGFWGSNGTVFIS
                     RDRQVLVTDSRYIIAAKQETSGFEIVADRDELAVIAGIVKDMNLTRIGFEDEISVSYY
                     HRMQAAFAGLNLLPQTQFVEGLRMIKDEAEIAAIRKACSISDQAFRDALDFIKPGKTE
                     IEIANFLDFRMRELGASGLSFDTILASGINSSKPHAHPMHKPVELGEAITMDFGCLYD
                     HYVSDMTRTIYLGHVSDEQAEIYNTVLKANQALIDQAKAGLGFRDFDKIPRDIIIEAG
                     YGDYFTHGIGHGIGLDIHEEPYFSQTSTETIKTGMALTDEPGIYIEGKYGVRIEDDIL
                     ITETGCELLTLAPKELIVI"
     gene            29891..30289
                     /gene="spx"
                     /locus_tag="VVR63_000030"
     CDS             29891..30289
                     /gene="spx"
                     /locus_tag="VVR63_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HEU6128099.1"
                     /translation="MIKIYTVSSCTSCKKAKTWLNAHQLSYKEQNLGKEGITREELLD
                     ILTKTDNGIASIVSSKNRYAKALGVDIEDLSVNEVLNLIMETPRILKSPILVDEKRLQ
                     VGYKEDDIRAFLPRSVRNVENAEARLRAAL"
     gene            30355..30924
                     /locus_tag="VVR63_000031"
     CDS             30355..30924
                     /locus_tag="VVR63_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEU6128100.1"
                     /translation="MKKIVLVSLAFLFVLVGCGQKKETGPATKTEKDTLQSALPVIEN
                     AEKNTVVTKTLVLPKSDDGSQQTQTITYKDKTFLSLAIQQKRPVSDELKTYIDQHGVE
                     ETQKALLEAEEKDKSIIEARKLAGFKLETKLLSATELQTTTSFDFQVLDVKKASQLEH
                     LKNIGLENLLKNEPSKYISDRLANGATEQ"
     gene            31011..31277
                     /locus_tag="VVR63_000032"
     CDS             31011..31277
                     /locus_tag="VVR63_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HEU6128101.1"
                     /translation="MGFTEETVRFKLDDSNKKEISETLTDVYASLNDKGYNPINQIVG
                     YVLSGDPAYVPRYNNARNQIRKYERDEIVEELVRYYLKGQGVDL"
     gene            31281..31700
                     /gene="ruvX"
                     /locus_tag="VVR63_000033"
     CDS             31281..31700
                     /gene="ruvX"
                     /locus_tag="VVR63_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HEU6128102.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIQINEEQGQFGFDR
                     VKELVDTYKVERFVVGLPKNMNNTSGPRVEASQAYGAKLEEFFGLPVDYQDERLTTVA
                     AERMLIEQADISRNKRKKVIDKLAAQLILQNYLDRKF"
     gene            31716..32021
                     /locus_tag="VVR63_000034"
     CDS             31716..32021
                     /locus_tag="VVR63_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HEU6128103.1"
                     /translation="MSHDHNHDHEERELITLVDEQGNETLFEILLTIDGKEEFGKNYV
                     LLVPVNAEEDEDGQVEIQAYSFIENEDGTEGELQPIPEDSEDEWNMIEEVFNSFMEE"
     gene            32279..33529
                     /locus_tag="VVR63_000035"
     CDS             32279..33529
                     /locus_tag="VVR63_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEU6128104.1"
                     /translation="MFEVEEWLHSRIGLNFRSGLGRMQQAVDLLGNPEQSYPIIHVTG
                     TNGKGSTIAFMRELFMGHGKKVATFTSPHIVSINDRICINGQPIADADFIRLTDQVKE
                     MEKTLLQTPAQLSFFELLTLVAFLYFREQEVDLVLLEVGIGGLLDTTNVVTGELAVIT
                     SIGLDHQETLGDSLEAIAEQKAGIFKAGKKAVIAKLPPEARLVCQKKAESLAVDLYQA
                     GQDFSVLNGDFSSSLLNLSQLNIGLEGAYQQENAALALQTFLLFMGERKEAIDEQAVR
                     KALEQTHWAGRLERIRPQIYLDGAHNLPALTRLVEFIKEKEQEGYRPQILFGSLKRKD
                     YQGMLGYLTENLPQVELKMTGFDYQGSLDETDVTGYHVIPSYREFISSFEERADAQDL
                     LFVTGSLYFISEVRGYLLDREQIN"
     gene            33526..34068
                     /locus_tag="VVR63_000036"
     CDS             33526..34068
                     /locus_tag="VVR63_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin/fatty acid-binding family protein"
                     /protein_id="HEU6128105.1"
                     /translation="MTPFFELVILGELLVRENFSKLVAERKFIMKLKRFTLSLASLAS
                     FSLLVACSQRAQQVQQPVAQQVQQPAQQNTNTANAGGNQNQAAPVQNQPVAQPTDIDG
                     TYTGQDDGDRITLVVTGTTGTWTELESDGDQKVKQVTFDSANQRMIIGDDVKIYTVNG
                     NQIVVDDMDRDPSDQIVLTK"
     gene            34214..35746
                     /gene="cls"
                     /locus_tag="VVR63_000037"
     CDS             34214..35746
                     /gene="cls"
                     /locus_tag="VVR63_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HEU6128106.1"
                     /translation="MKYRKFQLLMSKYGFSLSIMLLELCLVFGLFLYLGRMAPILWIT
                     VLILLSIITIISIVNRNTTPENKVTWLLVAFVPVFGPLLYLMFGERRLSKKEIKQLKK
                     LGSMHFQEANSQLLKEKLKESDKAAYGVIKSLLSMDTNADIYDQTASTFFPNGEAMWK
                     KMVEDLKKAEKFIFLEYYIIEEGLMWNRILDILEQKVAQGVEVKMLYDDIGCMATLTG
                     DYAHRLRQLGIEAHKFNKVIPRLTVAYNNRDHRKILIVDGQIAYTGGVNLADEYINHV
                     ERFGYWKDSGIRLDGLAVKALTRLFLTTWYINRGEISDFDQYHLENHSIPSDGLTIPY
                     GSGPKPIFRAQVGKKVYQSLINQATESVYITTPYLIIDYDLTETIKNAAMRGVDVRII
                     TPYIPDKKFIQLVTRGAYPDLLSAGVRIYEYSPGFIHSKQMLVDEDFAVVGTINLDYR
                     SLVHHYENAVLLYKTPSIREIARDFRNIFADSQEVYPHSIKTSWYQKLVKEIAQLFAP
                     IL"
     gene            35824..35967
                     /locus_tag="VVR63_000038"
     CDS             35824..35967
                     /locus_tag="VVR63_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000956126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6128107.1"
                     /translation="MLTKEEVNDMIEFKQTHLHRFREIETFVKLCKKSLKQPSQADNP
                     RTF"
     gene            36004..37542
                     /locus_tag="VVR63_000039"
     CDS             36004..37542
                     /locus_tag="VVR63_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HEU6128108.1"
                     /translation="MSVYGRVEEVHKENREPLEYQIEQESHHRESSRLPLVKILLWST
                     LVTGITLGVPLLLDLMSAQEVQDFYAGWGLHQTGKIYSDYYGSQGLLYYLLTYVSQGG
                     FFFAIFEWLALVAGGFFLFRSADTLTEQGDQAGHLVTIFYMLVTGLAFGGGYATLLAL
                     PFLFAAFSLVAAYLSNPSHDKGFVRIGLALAGGFFFAPLSSLLFIAVVSLGLLVFNLG
                     HRRFAHGFYQFLAVALGFSLVFYPTAYYSAATGSFGDAISGIRYPIDSIRFDFTSKIL
                     ENMFFYGLLSLGLGFVVCIFLGLFQSKPFKLYVISVPASLVVILGLILLFFSQEPLHA
                     SYLMVVFPVFLLLLVTNIKSQQRGRSARRSRRETPVSLWSRFFKGNLYLLVFGFVYLL
                     SVPFLMKFVLYPVPYQERNRLADLVKEETNTEDAIYAWDDTATLYRKSERLSPSAILS
                     PLHYTATEENRNKLLNDLKEKQPKVIVVNDKVVVWSEVETLLKENYQQVKTDYSEFKV
                     YKIK"
     gene            37662..39869
                     /gene="nrdD"
                     /locus_tag="VVR63_000040"
     CDS             37662..39869
                     /gene="nrdD"
                     /locus_tag="VVR63_000040"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004239081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HEU6128109.1"
                     /translation="MIALEEKITILPTLFVEKRDGRRVVFDVDKIDKALHKAADKVMD
                     VTPLVEKRLNDLTERIITEIHSRFPQGIKIYEIQNIVEHELLEAKEYALAEEYITYRT
                     QRDFERSKATDINFSIHKLLNKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLQML
                     PKHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLENGFKIGNAEVESPKSIQTA
                     TAQISQIIANVASSQYGGCSADRIDEILAPYAEKNYQKHLKDAEEWVLPEKREDYAWK
                     KTQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSRFEREIQKAILNIRIKGLG
                     SEHRTAIFPKLIFTLKRGLNLEEGTPNYDIKQLALECATKRMYPDVLSYDKIVDLTGS
                     FKVPMGCRSFLQGWKDENGVEVNSGRMNLGVVTVNLPRIALESEGDMNKFWEIFNERM
                     NIAEDALVYRVERTKEATPANAPILYQYGAFGHRLGKEESVDQLFKNRRATVSLGYIG
                     LYEVATVFFGNSWESNPDAKEFTLDIIHDMKRRVEEWSDQYGYHFSIYSTPSESLTDR
                     FCRLDIDKFGSIPDITDKEYYTNSFHYDVRKNPTPFEKLDFEKVYPEAGASGGFIHYC
                     EYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDRCYKCDFEGDFEPTERGFACPNCGN
                     SDPKTVDVVKRTCGYLGNPQARPMVNGRHKEIAARVKHMNGSTIKIAGHQVTN"
     gene            39881..40021
                     /locus_tag="VVR63_000041"
     CDS             39881..40021
                     /locus_tag="VVR63_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6128110.1"
                     /translation="MGKYQLDDKGRAQVTRYHEKHSKGGAGKKERLLSFREQFLNKNK
                     KK"
     gene            40065..40571
                     /locus_tag="VVR63_000042"
     CDS             40065..40571
                     /locus_tag="VVR63_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6128111.1"
                     /translation="MELRRPRLADKKAVLDMMTEFEKFQSPHDGGFWDTENFVYEDWL
                     ESNQEQEMGINLPEGWVPAIQLVAFSEKGQAVGFLNLRLRLSNFLLEEGGHIGYSIRP
                     SERGKGYAKETLRQGLQVAKEKNIKKALVTCSVNNPASRAVILANGGIFEDARNGVER
                     YWIEVANE"
     gene            40564..41154
                     /gene="nrdG"
                     /locus_tag="VVR63_000043"
     CDS             40564..41154
                     /gene="nrdG"
                     /locus_tag="VVR63_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001064213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HEU6128112.1"
                     /translation="MNNPKPQEWKSEELSQGRIIDYKAFNFVDGEGVRNSLYVAGCMF
                     HCEGCYNVATWSFNAGIPYTAELEEQIMADLAQPYVQGLTLLGGEPFLNTGILLPLVK
                     RIRKELPDKDIWSWTGYTWEEMMLETPDKLELLSLIDILVDGRYDRTKRNLMLQFRGS
                     SNQRIIDVQKSLKSGQVVIWDKLNDGKESYEQVKRE"
     gene            41151..41768
                     /locus_tag="VVR63_000044"
     CDS             41151..41768
                     /locus_tag="VVR63_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribulokinase"
                     /protein_id="HEU6128113.1"
                     /translation="MKKKDLVDQLVSEIETGKVRTLGIYGHGASGKSTFAQELYQALD
                     STTVNLLETDPYITSGRYLVVPKDAPNQKVTASLPVAHELESLQRDILALQAGMDVLT
                     IEEPWKASEVLSGAKPILIVEGMSVGFLPKELFEKTICFYTDEETELKRRLARDTTVR
                     NRDASFILASHQMRREQYLRYYKETESKADILVDQSEDKFDVKRT"
     gene            42035..42343
                     /gene="rpsJ"
                     /locus_tag="VVR63_000045"
     CDS             42035..42343
                     /gene="rpsJ"
                     /locus_tag="VVR63_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HEU6128114.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAAKIVESATRTGAQVAGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            42559..43185
                     /gene="rplC"
                     /locus_tag="VVR63_000046"
     CDS             42559..43185
                     /gene="rplC"
                     /locus_tag="VVR63_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HEU6128115.1"
                     /translation="MTKGILGKKVGMTQIFTEAGELIPVTVIEATPNVVLQVKTVETD
                     GYNAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNVEGLEVGAEITVETFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKGKNLAG
                     RMGGDRVTIQNLEVVQVVPEKNVILIKGNVPGAKKSLITIKSAVKAGK"
     gene            43210..43833
                     /gene="rplD"
                     /locus_tag="VVR63_000047"
     CDS             43210..43833
                     /gene="rplD"
                     /locus_tag="VVR63_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HEU6128116.1"
                     /translation="MANVTLFDQTGKEAGQVVLNDAVFGIEPNESVVFDVIISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSEKVAENKFVAVDALSFTAPKTAEFAKVLAALSIDSKVLVILEEGN
                     EFAALSARNLPNVKVATATTASVLDIANSDKLLVTQAAISKIEEVLA"
     gene            43833..44129
                     /locus_tag="VVR63_000048"
     CDS             43833..44129
                     /locus_tag="VVR63_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HEU6128117.1"
                     /translation="MNLYDVIKKPVITESSMAQLEAGKYVFEVDTRAHKLLIKQAVEA
                     AFEGVKVANVNTINVKPKAKRVGRYTGFTNKTKKAIITLTADSKAIELFAAEAE"
     gene            44147..44980
                     /gene="rplB"
                     /locus_tag="VVR63_000049"
     CDS             44147..44980
                     /gene="rplB"
                     /locus_tag="VVR63_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HEU6128118.1"
                     /translation="MGIRVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVALKSKAGRN
                     NNGRITVRHQGGGHKRFYRLVDFKRNKDNVEAVVKTIEYDPNRSANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPEADIKVGNALPLANIPVGTLIHNIELKPGRGGELVRAAGA
                     SAQVLGSEGKYVLVRLQSGEVRMILGTCRATVGVVGNEQHGLVNLGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNE
                     K"
     gene            45084..45365
                     /gene="rpsS"
                     /locus_tag="VVR63_000050"
     CDS             45084..45365
                     /gene="rpsS"
                     /locus_tag="VVR63_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HEU6128119.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRRK"
     gene            45377..45721
                     /gene="rplV"
                     /locus_tag="VVR63_000051"
     CDS             45377..45721
                     /gene="rplV"
                     /locus_tag="VVR63_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HEU6128120.1"
                     /translation="MAEITSAKAMARTVRVSPRKSRLVLDNIRGKSVADAIAILTFTP
                     NKAAEIILKVLNSAVANAENNFGLDKANLVVSEAFANEGPTMKRFRPRAKGSASPINK
                     RTAHITVAVAEK"
     gene            45734..46387
                     /gene="rpsC"
                     /locus_tag="VVR63_000052"
     CDS             45734..46387
                     /gene="rpsC"
                     /locus_tag="VVR63_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HEU6128121.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFVQK
                     ELADAAVSTIEIERAVNKVNVSLHTAKPGMVIGKGGANVDALRAKLNKLTGKQVHINI
                     IEIKQPDLDAHLVGEGIARQLEQRVAFRRAQKQAIQRAMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            46391..46804
                     /gene="rplP"
                     /locus_tag="VVR63_000053"
     CDS             46391..46804
                     /gene="rplP"
                     /locus_tag="VVR63_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HEU6128122.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQATTSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            46814..47020
                     /locus_tag="VVR63_000054"
     CDS             46814..47020
                     /locus_tag="VVR63_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HEU6128123.1"
                     /translation="MKLNEVKEFVKELRGLSQEELAKRENELKKELFELRFQAATGQL
                     EQTARLKEVKKQIARIKTVQSEAK"
     gene            47045..47305
                     /gene="rpsQ"
                     /locus_tag="VVR63_000055"
     CDS             47045..47305
                     /gene="rpsQ"
                     /locus_tag="VVR63_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HEU6128124.1"
                     /translation="MERNNRKVLVGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEEAVII"
     gene            47331..47699
                     /gene="rplN"
                     /locus_tag="VVR63_000056"
     CDS             47331..47699
                     /gene="rplN"
                     /locus_tag="VVR63_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HEU6128125.1"
                     /translation="MIQTETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRADGSYIKFDENAAVIIREDKTPRGTRIFGPV
                     ARELREGGFMKIVSLAPEVL"
     gene            47777..48082
                     /gene="rplX"
                     /locus_tag="VVR63_000057"
     CDS             47777..48082
                     /gene="rplX"
                     /locus_tag="VVR63_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HEU6128126.1"
                     /translation="MFVKKGDKVRVIAGKDKGTEAVVLTALPKVNKVIVEGVNIVKKH
                     QRPTNELPQGGIIEKEAAIHVSNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            48106..48648
                     /gene="rplE"
                     /locus_tag="VVR63_000058"
     CDS             48106..48648
                     /gene="rplE"
                     /locus_tag="VVR63_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HEU6128127.1"
                     /translation="MANRLKEKYLNEVVPALTEQFNYSSVMAVPKVDKIVLNMGVGEA
                     VSNAKSLEKAAEELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKTRGLDIVIVTT
                     ANTDEESRALLTGLGMPFAK"
     gene            48666..48935
                     /gene="rpsN"
                     /locus_tag="VVR63_000059"
     CDS             48666..48935
                     /gene="rpsN"
                     /locus_tag="VVR63_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HEU6128128.1"
                     /translation="MAKKSMVAREAKRQKIVDRYAEKRAALKAAGDYEGLSKLPRNAS
                     PTRLHNRCRVTGRPHSVYRKFGLSRIAFRELAHKGQIPGVTKASW"
     gene            49220..49618
                     /gene="rpsH"
                     /locus_tag="VVR63_000060"
     CDS             49220..49618
                     /gene="rpsH"
                     /locus_tag="VVR63_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HEU6128129.1"
                     /translation="MVMTDPIADFLTRIRNANQAKHEVLEVPASNIKKGIAEILKREG
                     FVKNVEIIEDDKQGVIRVFLKYGPNGEKVITNLKRVSKPGLRVYKKREDLPKVLNGLG
                     IAILSTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            49810..50346
                     /gene="rplF"
                     /locus_tag="VVR63_000061"
     CDS             49810..50346
                     /gene="rplF"
                     /locus_tag="VVR63_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HEU6128130.1"
                     /translation="MSRIGNKVIVLPAGVELANNDNVVTVKGPKGELTREFSKDIEIR
                     VEGTEITLHRPNDSKEMKTIHGTTRALLNNMVVGVSEGFKKELEMRGVGYRAQLQGSK
                     LVLAVGKSHPDEVEAPEGITFELPNPTTIVVSGISKEVVGQTAAYVRSLRSPEPYKGK
                     GIRYVGEFVRRKEGKTGK"
     gene            50430..50786
                     /gene="rplR"
                     /locus_tag="VVR63_000062"
     CDS             50430..50786
                     /gene="rplR"
                     /locus_tag="VVR63_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HEU6128131.1"
                     /translation="MISKPDKNKLRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVAVGKLVAERANAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            50804..51298
                     /gene="rpsE"
                     /locus_tag="VVR63_000063"
     CDS             50804..51298
                     /gene="rpsE"
                     /locus_tag="VVR63_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HEU6128132.1"
                     /translation="MAFKDNAVELEERVVAVNRVTKVVKGGRRLRFAALVVVGDHNGR
                     VGFGTGKAQEVPEAIRKAVDDAKKNLIEVPMVGTTIPHEVLSEFGGAKVLLKPAVEGS
                     GVAAGGAVRAVVELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEIAALRGISV
                     SDLA"
     gene            51270..51494
                     /gene="rpmD"
                     /locus_tag="VVR63_000064"
     CDS             51270..51494
                     /gene="rpmD"
                     /locus_tag="VVR63_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HEU6128133.1"
                     /translation="MVFQFLIWHKKGDKMAQIKITLTKSPIGRIPSQRKTVVALGLGK
                     LNSSVIKEDNAAIRGMITAVSHLVTVEEVN"
     gene            51639..52079
                     /gene="rplO"
                     /locus_tag="VVR63_000065"
     CDS             51639..52079
                     /gene="rplO"
                     /locus_tag="VVR63_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HEU6128134.1"
                     /translation="MKLHELKPAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNINAKEYAIVNLDQLNVFEDGAEVTPVVLIEAGIV
                     KAEKSGIKILGNGELTKKLTVKAAKFSKSAEEAITAKGGSVEVI"
     gene            52092..53402
                     /gene="secY"
                     /locus_tag="VVR63_000066"
     CDS             52092..53402
                     /gene="secY"
                     /locus_tag="VVR63_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HEU6128135.1"
                     /translation="MFFKLLREALKVKQVRSKILFTIFIVLVFRIGTSITVPGVNANS
                     LNALSGLSFLNMLSLVSGNALKNFSIFALGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYIALVLAFVQSIGITAGFNTLAGAQLIKTALTPQVFLTIGIILTA
                     GSMIVTWLGEQITDKGYGNGVSMIIFAGIVSSIPEMIQGIYVDYFVNVPSSRITSSII
                     FVIILIITVLLIIYFTTYVQQAEYKIPIQYTKVAQGAPSSSYLPLKVNPAGVIPVIFA
                     SSITAAPAAILQFLSATGHDWAWVRVAQEMLATTSPTGIAMYALLIILFTFFYTFVQI
                     NPEKAAESLQKSGAYIHGVRPGKGTEEYMSKLLRRLATVGSLFLGVISILPIAAKDVF
                     GLSDVVAFGGTSLLIIISTGIEGIKQLEGYLLKRKYVGFMDRTE"
     gene            53553..54191
                     /locus_tag="VVR63_000067"
     CDS             53553..54191
                     /locus_tag="VVR63_000067"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HEU6128136.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVEQFHVAHISTGDMFRAAMANQTE
                     MGVLAKSYIDKGELVPDEVTNGIVKERLSQDDIKETGFLLDGYPRTIEQAHALDKTLA
                     ELGIELEGIINIEVNPDSLLERLSGRIIHRVTGETFHKVFNPPVDYKEEDYYQREDDK
                     PETVKRRLDVNIAQGEPIIAHYRAKGLVHDIEGNQDINDVFSDIEKVLTNLK"
     gene            54308..54526
                     /gene="infA"
                     /locus_tag="VVR63_000068"
     CDS             54308..54526
                     /gene="infA"
                     /locus_tag="VVR63_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HEU6128137.1"
                     /translation="MAKDDVIEVEGKVVDTMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILAGDRVTVEMSPYDLTRGRITYRFK"
     gene            54551..54667
                     /gene="rpmJ"
                     /locus_tag="VVR63_000069"
     CDS             54551..54667
                     /gene="rpmJ"
                     /locus_tag="VVR63_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HEU6128138.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPANPKHKQRQG"
     gene            54685..55050
                     /gene="rpsM"
                     /locus_tag="VVR63_000070"
     CDS             54685..55050
                     /gene="rpsM"
                     /locus_tag="VVR63_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HEU6128139.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDVR
                     VRDLTSDQEDAIRREVDAIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            55068..55451
                     /gene="rpsK"
                     /locus_tag="VVR63_000071"
     CDS             55068..55451
                     /gene="rpsK"
                     /locus_tag="VVR63_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HEU6128140.1"
                     /translation="MAKPTRKRRVKKNIESGIAHIHATFNNTIVMITDVHGNAIAWSS
                     AGALGFKGSRKSTPFAAQMASEAAAKSAQEHGLKSVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            55494..56429
                     /locus_tag="VVR63_000072"
     CDS             55494..56429
                     /locus_tag="VVR63_000072"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HEU6128141.1"
                     /translation="MIEFEKPNITKIDENKDYGKFVIEPLERGYGTTLGNSLRRVLLA
                     SLPGAAVTSINIDGVLHEFDTVPGVREDVMQIILNIKGIAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIEIVNPDHYLFTIGEGSSLKATMTVNSGRGYVPADENKKDNAPVG
                     TLAVDSIYTPVTKVNYQVEPARVGSNDGFDKLTLEILTNGTIIPEDALGLSARILTEH
                     LDLFTNLTEIAKSTEVMKEADTESDDRILDRTIEELDLSVRSYNCLKRAGINTVHDLT
                     EKSEAEMMKVRNLGRKSLEEVKLKLIDLGLGLKDK"
     gene            56441..56827
                     /gene="rplQ"
                     /locus_tag="VVR63_000073"
     CDS             56441..56827
                     /gene="rplQ"
                     /locus_tag="VVR63_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HEU6128142.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDFLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAFVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            57092..57358
                     /locus_tag="VVR63_000074"
     CDS             57092..57358
                     /locus_tag="VVR63_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002905356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HEU6128143.1"
                     /translation="MKAIITVVGKDKSGIVAGVSGKIAELGLNIDDISQTVLDEYFTM
                     MAVVSSDEKQDFTYLRNEFEAFGQTLNVKINIQSAAIFEAMYNI"
     gene            57368..58705
                     /locus_tag="VVR63_000075"
     CDS             57368..58705
                     /locus_tag="VVR63_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HEU6128144.1"
                     /translation="MDIRQVTETIAMIEEQNFDIRTITMGISLLDCIDPNINRAAEKI
                     YQKITTKAANLVAVGDEIAAELGIPIVNKRVSVTPISLIGAATDATDYVVLAKALDKA
                     AKEIGVDFIGGFSALVQKGYQKGDEILINSIPRALAETDKVCSSVNIGSTKSGINMTA
                     VADMGRIIKETANLSDMGVAKLVVFANAVEDNPFMAGAFHGVGEADVIINVGVSGPGV
                     VKRALEKVRGQSFDVVAETVKKTAFKITRIGQLVGQMASERLGVEFGIVDLSLAPTPA
                     VGDSVARVLEEMGLETVGTHGTTAALALLNDQVKKGGVMACNQVGGLSGAFIPVSEDE
                     GMIAAVQNGSLNLEKLEAMTAICSVGLDMIAIPEDTPAETIAAMIADEAAIGVINMKT
                     TAVRIIPKGREGDMIEFGGLLGTAPVMKVNGASSVDFISRGGQIPAPIHSFKN"
     gene            58949..59641
                     /locus_tag="VVR63_000076"
     CDS             58949..59641
                     /locus_tag="VVR63_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEU6128145.1"
                     /translation="MVKVRLYLVRHGKTMFNTIGRAQGWSDTPLTAEGERGIQELGIG
                     LRESDLQFERAYSSDSGRTIQTMGIILEELGLQGKIPYRMDKRIREWCFGSFDGAYDG
                     DLFMGIIPRIFNVDHVHQLSYAELAEGLVEVDTAGWAEGWEKLSGRIKEGFEIIAKEM
                     EDQGGGNALVVSHGMTIGTIVYLINGMHPHGLDNGSVTILEYEDGQFRVEVVGDRSYR
                     ELGREKMEEGSI"
     gene            complement(59744..61379)
                     /locus_tag="VVR63_000077"
                     /pseudo
     CDS             complement(59744..61379)
                     /locus_tag="VVR63_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520796.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
     gene            complement(61369..62460)
                     /locus_tag="VVR63_000078"
     CDS             complement(61369..62460)
                     /locus_tag="VVR63_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001289362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6128146.1"
                     /translation="MSEIEIINAKKIYHDVPVIENLNITIPKGSLFTLLGASGCGKTT
                     LLRMIAGFNSIKDGEFYFDDTKINNMEPSKRNIGLVFQNYAIFPHLTVRDNVAFGLMQ
                     KKVPKEELIQQTNKYLELMQIAQYADRKPDKLSGGQQQRVTLACALAVNPSVLLMDEP
                     LSNLEAKLRLDMRQTIREIQHEVGITTVYVTHDQEEAMAISDQIAVMKDGVIQQIGRP
                     KELYHKPANEFVATFIGRTNIIPANLEKRSDGAYIVFSDGYALRMLALDQVEEQAIHV
                     SIRPEEFIKDESGDIEGTISDSVYLGLNTEYFIETGFASKIQVSEESTFEEDLQKGNR
                     IRLRINTQKLNIFSADGSQNLIKGVNHGM"
     gene            complement(62473..63594)
                     /locus_tag="VVR63_000079"
                     /pseudo
     CDS             complement(62473..63594)
                     /locus_tag="VVR63_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931989.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
     gene            complement(63811..64008)
                     /locus_tag="VVR63_000080"
     CDS             complement(63811..64008)
                     /locus_tag="VVR63_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEU6128147.1"
                     /translation="MTLNEYILQYRLKQAIDKMAESPNSPLSAISDQVGFSDYKYFAK
                     VFKKYLHISPKKLKSLGRIVK"
     gene            complement(64083..64859)
                     /locus_tag="VVR63_000081"
     CDS             complement(64083..64859)
                     /locus_tag="VVR63_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000406168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HEU6128148.1"
                     /translation="MEISKGIIFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCSNPESQ
                     RMKPEKMKDAQREKFTLVGEEKTVEEIITEVLKDKEFYEESGGGLTLSGGEIFAQFEF
                     AKAILKSAKEHHIHTAIETTAFVDHEKFIDLIQYVDFIYTDLKHYNSIKHKKVTGVFN
                     QMIIKNIHYAFSQNKTIVLRIPVIPNFNNSLEDAEKFATLFNSLNIDQVQLLPFHQFG
                     ENKYRLLNRKYEMDGVNALHPEDLIDYQKVFLNHHINCYF"
     gene            64981..65727
                     /locus_tag="VVR63_000082"
     CDS             64981..65727
                     /locus_tag="VVR63_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEU6128149.1"
                     /translation="MKRLEQIIKLVSEYEKIDVNTLSEKLNVSKVTIRKDLDKLESKG
                     LLHREHGYAVLNSGDDLNVRLSINYEIKRKIVQEAVKLVSDNETIMIESGSTCALLAE
                     EICKQKRNVTIVTNSFFIANFVRAYDSCRIIVLGGEFQKDSQVTVGPLLKEMIQTFHV
                     HQAFVGTDGYDKEMGFTGKDLMRSEVVQYISAASDKVIVLTDSSKFDKRGTVRRFALS
                     QVYEVITDEKLSKQNIATLENAGIMVKVVS"
     gene            65740..66720
                     /locus_tag="VVR63_000083"
     CDS             65740..66720
                     /locus_tag="VVR63_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HEU6128150.1"
                     /translation="MNQDRNKLLSKIAYLYYIENLNQSQIAAKLGIYRTSISRMLTEA
                     RNAGIVKIEIENFDTNMFKLENYVKEKYGLESLEIIPNEFDDNPTILSERISQVAAGV
                     LRNLIDDNMKIGFSWGKSLSNLVDLIHSKSVRNVHFYPLAGGPSHIHAKYHVNTLIYE
                     MSRKFHGECTFMNATIVQENKLLADGILQSRYFENLKNSWKDLDIAVVGIGDFSNKGK
                     HQWLDMLTEDDFKELTKVKTVGEICCRFFDSKGKEVYENLQERTIAISLEDLKNIPQS
                     LAVAYGDTKVSSILSVLRANLVNHLITDKNTILKVLEEDGDLTFREILGE"
     gene            66915..67235
                     /locus_tag="VVR63_000084"
     CDS             66915..67235
                     /locus_tag="VVR63_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEU6128151.1"
                     /translation="MEIIVPDQIIMGLILYAGDAKQHIYKALDYIKNGTCERCEEEIQ
                     LADAALLEAHNLQTKFLAQEASGTKTEITALFVHSQDHLMTSMTEINLIKEIISLRKE
                     LHKK"
     gene            67281..67589
                     /locus_tag="VVR63_000085"
     CDS             67281..67589
                     /locus_tag="VVR63_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU6128152.1"
                     /translation="MVKIGLFCAAGFSTGMLVNNMKIAAQASGVEAEIEAFSQSKLAD
                     YAPNIDVALLGPQVAYTLDKSKEICDKCDVPIAVIPMMDYGMLDGKKVLDLALSLISG
                     "
     gene            67606..68904
                     /locus_tag="VVR63_000086"
     CDS             67606..68904
                     /locus_tag="VVR63_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEU6128153.1"
                     /translation="MAKMDVQKIIAPMMKFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     MGQLPFEGLNKSIASVFGANWTEPFMQVYSGTFAIMGLISCFSIAYSYAKNSGVEALP
                     AGVLSVSAFFILLRSSYIPKQGEAIGDAISKVWFGGQGIIGAIIIGLVVGSIYTFFIK
                     RKIVIKMPEQVPQAIAKQFEAMIPAFVIFLSSMIVYILAKSLTNGGTFIEMIYSAIQV
                     PLQGLTGSLYGAIGIAFFISFLWWFGVHGQSVVNGVVTALLLSNLDANKAMLASGNLS
                     LENGAHIVTQQFLDSFLILSGSGITFGLVVAMLFAAKSKQYQALGKVAAFPAIFNVNE
                     PVVFGFPIVMNPVMFVPFILVPVLAAVIVYGAIATGFMQPFSGVTLPWSTPAILSGFL
                     VGGWQGVVTQLLVLVISTVVYFPFFKIQDRLAYQNEIKQS"
     gene            69055..71493
                     /locus_tag="VVR63_000087"
     CDS             69055..71493
                     /locus_tag="VVR63_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HEU6128154.1"
                     /translation="MVNTEVARTTIKTEYFGSLTERMNKYREDVLNKKPYIDAERAVL
                     ATRAYERYKEQPNVLKRAYMLKEILENMSIYIEEESMIAGNQASSNKDAPIFPEYTLE
                     FVLNELDLFEKRDGDVFYITEETKEQLRSIAPFWENNNLRARAGALLPEEVSVYMETG
                     FFGMEGKMNSGDAHLAVNYQKLLQFGLRGFEERARKAKVALDLTDPASIDKYHFYDSI
                     FIVIDAIKVYAKRFVALAKSLAENANPKRKKELLEIADICSRVPYEPATTFAEAIQSV
                     WFIQCILQIESNGHSLSYGRFDQYMYPYMKADLESGKETEDSIVERLTNLWIKTITIN
                     KVRSQSHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLKSVAQTHLPQPNLTVRY
                     HAGLDARFMNECIEVMKLGFGMPAFNNDEIIIPSFIAKGVLEDDAYDYSAIGCVETAV
                     PGKWGYRCTGMSYMNFPKVLLITMNDGIDPASGKRFAPSFGHFKDMKNFSELENAWDK
                     TLRYLTRMSVIVENSIDLSLEREVPDILCSALTDDCIGRGKHLKEGGAVYDYISGLQV
                     GIANLSDSLAAIKKLVFEEERISPSQLWHALETDYAGEEGKVIQEMLIHDAPKYGNDD
                     DYADKLVTAAYDIYVDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGRGTLATPDG
                     RNAGTPLAEGCSPSHNMDQHGPTSVLKSVSKLPTDEIVGGVLLNQKVNPQTLAKEEDK
                     LKLIALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFNVLSK
                     ATQDDIIGRTEHTL"
     gene            71512..72180
                     /locus_tag="VVR63_000088"
     CDS             71512..72180
                     /locus_tag="VVR63_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HEU6128155.1"
                     /translation="MEFMLDTLNLDEIKKWSEILPLAGVTSNPTIAKREGSINFFERI
                     KDVRELIGSTPSIHVQVISQDFEGILKDAHKIRRQAGDDIFIKVPVTPAGLRAIKALK
                     KEGYHITATAIYTVIQGLLAIEAGADYLAPYYNRMENLNIDSNSVIRQLALAIDRQNS
                     PSKILAASFKNVAQVNNALAAGAHAVTAGADVFESAFAMPSIQKAVDDFSDDWFVIQN
                     SRSI"
     gene            72198..73286
                     /locus_tag="VVR63_000089"
     CDS             72198..73286
                     /locus_tag="VVR63_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HEU6128156.1"
                     /translation="MRIFASPSRYIQGENALFENAKSILDLGNYPILLCDQLVYDIVG
                     KRFEDYLHRYGFHIVLALFNGEASDNEINRVVALAEKENCDSIIGLGGGKTIDSAKAI
                     ADLIEKPVIIAPTIASTDAPVSALSVIYTDEGAFDHYLFYSKNPDLVLVDTKVISQAP
                     KRLLASGIADGLATWVEARAVMQANGKTMLGQQQTLAGVAIAKKCEETLFADGLQAMA
                     ACEAKVVTPALENIVEANTLLSGLGFESGGLAAAHAIHNGFTALTGDIHHLTHGEKVA
                     YGTLVQLLLENRPKEELDKYIEFYKKIGMPTTLKEMHLDQVGYDDLIKVGKQATMEGE
                     TIHQMPFKISPSDVAQAIIAVDAYVNSK"
     gene            73741..76242
                     /locus_tag="VVR63_000090"
     CDS             73741..76242
                     /locus_tag="VVR63_000090"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HEU6128157.1"
                     /translation="MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKD
                     MQRNWIGKSTGANVTFKVKGTDKEFTVFTTRPDTLFGATFTVLAPEHELVDAITSSEQ
                     AEAVADYKHQASLKSDLVRTDLAKEKTGVWTGAYAINPVNGKEMPIWIADYVLASYGT
                     GAVMAVPAHDQRDWEFAKQFDLPIVEVLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDA
                     IAKIVACLEEKGCGQEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPETELPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NTEKLADEDLLKQWLPVDIYVGGAEHAVLHLLYARFWHKFLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVATDKVEKRDGSFFHIETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITSKEILAENNGALD
                     KAYNETVKAVTEQIESLKFNTAIAQLMVFVNAANKEDKLYVDYAKGFIQLIAPFAPHL
                     AEELWQTVAETGESISYVAWPTWDESKLVEDEIEIVVQIKGKVRAKLMVAKDLSREEL
                     QEIALADEKVKAEIDGKEIVKVISVPNKLVNIVVK"
     gene            76436..77131
                     /locus_tag="VVR63_000091"
     CDS             76436..77131
                     /locus_tag="VVR63_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001144916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6128158.1"
                     /translation="MPVNEYGQMIGESMEGYTPGELPSIDFLEGRYARIEALSVEKHA
                     EDLLAVYGPDTPREMWTYLFQEPVADMGELVSLLHQMLARKDRFYYAIIDKATGKALG
                     SFSLMRIDQNNRVIEVGAVTFSPELRGTRIGTEAQYLLARYVFEELNYRRYEWKCDAL
                     NLPSRRAAERLSFIYEGTFRQAVVYKGRTRDTDWLSMIDKDWPQVKDRLETWLRPENF
                     DKNGQQYKSLREL"
     gene            77143..77559
                     /locus_tag="VVR63_000092"
     CDS             77143..77559
                     /locus_tag="VVR63_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6128159.1"
                     /translation="MITIKKQEIVKLEDVLHLYQAVGWTNYTHQPEMLEQALSHSLVI
                     YLALDGDAVVGLIRLVGDGFSSVLVQDLIVLPIYQRQGIGSALMKEALEDYKDAYQVQ
                     LVTEETERTLGFYRSMGFEILSTYNCIGMTWMNRKK"
     gene            complement(78374..78466)
                     /locus_tag="VVR63_000093"
     CDS             complement(78374..78466)
                     /locus_tag="VVR63_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HEU6128160.1"
                     /translation="MMELVLKTIIGPIVVGVVLRIVDKWLNKDK"
     gene            78627..79598
                     /gene="ruvB"
                     /locus_tag="VVR63_000094"
     CDS             78627..79598
                     /gene="ruvB"
                     /locus_tag="VVR63_000094"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000502070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HEU6128161.1"
                     /translation="MGDEELVERTLRPQYLREYIGQDKVKDQLQIFIEAAKMRDEALD
                     HVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPVIEKAGDLVAILNELEPGDVLFIDE
                     IHRLPMSVEEVLYSAMEDFYIDIMIGAGEGSRSVHLELPPFTLIGATTRAGMLSNPLR
                     ARFGITGHMEYYAHAGLTEIVERTADIFEMEITHEAASELALRSRGTPRIANRLLKRV
                     RDFAQIMGNGVIDDIITDKALTMLDVDHEGLDYVDQKILRTMIEMYSGGPVGLGTLSV
                     NIAEERETVEDMYEPYLIQKGFIMRTRSGRVATAKAYEHLGYEYSEK"
     gene            79579..80151
                     /locus_tag="VVR63_000095"
     CDS             79579..80151
                     /locus_tag="VVR63_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001098890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HEU6128162.1"
                     /translation="MNTVKNKQEILEAFRENPDMMAILTIIRDLGLKDSWLAAGSVRN
                     FIWNLLSDKSPFDHETDIDVIFFDPDFSYEETLLLEKKLREDFPQYQWELKNQVYMHQ
                     HSPHTASYTSSRDAMSKYPERCTTVGLRLNEESDFELYAPYGLEDILNFQVRPTPHFL
                     ENEDRMELYQTRLSKKNWQEKWKNLIFKNT"
     gene            80382..81140
                     /locus_tag="VVR63_000096"
     CDS             80382..81140
                     /locus_tag="VVR63_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HEU6128163.1"
                     /translation="MFGFFKKDKAVEVEVPTQVPAHIGIIMDGNGRWAKKRMQPRVFG
                     HKAGMEALQTVTKAANKLGVKVITVYAFSTENWTRPDQEVKFIMNLPVEFYDNYVPEL
                     HANNVKIQMIGETDRLPKQTFEALTKAEELTKNNTGLILNFALNYGGRAEITQALKLI
                     SQDVLDAKINPGDITEELIGNYLFTQHLPKDLRDPDLIIRTSGELRLSNFLPWQGAYS
                     ELYFTDTLWPDFDEAALQEAILAYNRRHRRFGGV"
     gene            81149..81952
                     /locus_tag="VVR63_000097"
     CDS             81149..81952
                     /locus_tag="VVR63_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HEU6128164.1"
                     /translation="MTQDLQKRTLFAGIALAIFLPILMIGGLLLQIAIGIIAMLAMHE
                     LLKIRGLATMTMEGLLTLFATFALTIPLENYLTFLPVDGNVVAYSVLISIMLGTTVFS
                     KSYTIEDAVFPLAMSFYVGFGFNALLDARVAGLDKALLALCIVWATDSGAYLVGMNYG
                     KRKLAPRVSPNKTLEGALGGILGAILVTIIFMIVDSTVALPYGIYKMSVFAIFFSIAG
                     QFGDLLESSIKRHFGVKDSGKFIPGHGGVLDRFDSMLLVFPIMHLFGLF"
     gene            81974..83233
                     /gene="rseP"
                     /locus_tag="VVR63_000098"
     CDS             81974..83233
                     /gene="rseP"
                     /locus_tag="VVR63_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HEU6128165.1"
                     /translation="MLGILTFILVFGIIVVVHEFGHFYFAKKSGILVREFAIGMGPKI
                     FAHIGKDGTAYTIRILPLGGYVRMAGWGDDTTEIKTGTPVSLTLADDGKVKRINLSGK
                     KLDQTALPMQVTQFDFEDKLFIKGLVLEEEKTFAVDHDATVVEADGTEVRIAPLDVQY
                     QNATIWGKLITNFAGPMNNFILGVVVFWVLIFMQGGVRDVDTNQFHIMPQGALAKVGV
                     PETAQITKIGSHEVSNWESLIQAVETETKDKTAPTLDVTISEKGSDKQVTVTPEDSQG
                     RYLLGVQPGVKSDFLSMFVGGFTTAADSALRILSALKNLIFQPDLNKLGGPVAIFKAS
                     SDAAKNGIENILYFLAMISINIGIFNLIPIPALDGGKIVLNILEAIRHKPLKQEIETY
                     VTLAGVVIMVVLMIAVTWNDIMRLFFR"
     gene            83246..85099
                     /locus_tag="VVR63_000099"
     CDS             83246..85099
                     /locus_tag="VVR63_000099"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HEU6128166.1"
                     /translation="MKQSKMPIPTLREMPSDTQVISHALMLRAGYVRQVSAGVYSYLP
                     LANRVIEKAKNIMRQEFEKIGAVEMLAPTLLSAELWRESGRYETYGEDLYKLKNREKS
                     DFILGPTHEETFTAIVRDSVKSYKQLPLNLYQIQPKYRDEKRPRNGLLRTREFIMKDA
                     YSFHANYDSLDSVYDEYKAAYERIFTRSGLDFKAIIGDGGAMGGKDSQEFMAITSART
                     DLDRWVVLDKSVASFDEIPAEVQEEIKAELLKWIVSGEDTIAYSSESSYAANLEMATN
                     EYKPSNRVVAEEEVTRVATPDVKSIDEVAAFLNVPEEQTIKTLFYIADGELVAALLVG
                     NDQLNEVKLKNHLGADFFDVASEEEVANVVQAGFGSLGPVGLPENIKIIADRKVQDVR
                     NAVVGANEDGYHLTGVNPGRDFTAEYVDIREVREGEISPDGQGVLNFARGIEIGHIFK
                     LGTRYSASMGADVLDENGRAVPIIMGCYGIGVSRLLSAVMEQHARLFVNKTPKGEYRY
                     AWGINFPKELAPFDVHLITVNVKDEEAQALTEKLEASLMGAGYEVLTDDRNERVGVKF
                     SDSDLIGLPIRITVGKKAADGIVEVKIKATGDTIEVHADNVLETLEILSKK"
     gene            85199..86578
                     /gene="bglA"
                     /locus_tag="VVR63_000100"
     CDS             85199..86578
                     /gene="bglA"
                     /locus_tag="VVR63_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000943526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HEU6128167.1"
                     /translation="MLRFPKDFVWGSSTSGPQTEGRVAGDGKGDNLWDYWFQVEPNRY
                     YNGIGSDKTSTFYENWERDIELLLETGHTVFRTSIQWSRIFPQGCGKVNPQGVDFYRK
                     VFEAIKAKGIRLLVNLYHFDLPFALQEDGDGWENKATVSAYEDYARFCFETYGDLVDQ
                     WITFNEPIVPVEFGYFYDAHYPHKVDAEAAVKVAYHTQLASSRAVKACHELLPDSKIG
                     IVLNLTPAYPRSQHPADVKAARIAALFQAQSFLDPSVLGTYPQELVEILHEHGLLPDA
                     TEEELELIRDNTVDFLGVNYYQPLRVMAPRFAKHPDSPLLPEHFYEPYVMPGRKINSH
                     RGWEIYEQGIYDIAQNIKENYGNIEWMLTENGMGVEGEEKFRQDGMIQDDYRIDFVKG
                     HLRELHRAIEDGANCKGYLIWTFIDCWSWLNSYKNRYGLVELDLETQERRLKKSGHWF
                     KELSDNNGF"
     gene            86770..88578
                     /gene="glmS"
                     /locus_tag="VVR63_000101"
     CDS             86770..88578
                     /gene="glmS"
                     /locus_tag="VVR63_000101"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014621492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HEU6128168.1"
                     /translation="MCGIVGVVGNTNATDILIQGLEKLEYRGYDSAGIFVLDGADNHL
                     VKAVGRIAELSAKTAGVEGTTGIGHTRWATHGKPTEDNAHPHRSETERFVLVHNGVIE
                     NYLEIKEEYLAGHHFKGQTDTEIAVHLIGKFAEEDGLSVLEAFKKALHIIRGSYAFAL
                     IDSENPDVIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETNQYMEIHDQELVIVKADS
                     VEVQDYDGNSRERASYTAELDLSDIGKGTYPYYMLKEIDEQPTVMRKLIQAYTDDAGQ
                     VVIDPAIIKAVQDADRIYILAAGTSYHAGFASKKMLEELTDTPVELGISSEWGYGMPL
                     LSKKPLFIFISQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREANYTMLLHAGP
                     EIAVASTKAYTAQIAALAFLAKAVGEANGNAKAQAFDLVHELSIVAQSIESTLSEKET
                     IEAKVRELLETTRNAFYIGRGQDYYVAMEASLKLKEISYIQCEGFAAGELKHGTIALI
                     EEGTPVLALLSDPVLANHTRGNIQEVAARGAKVLTIAEENVAKDTDDIVLTTVHPYLS
                     PISMVVPTQLVAYFATLHRGLDVDKPRNLAKSVTVE"
     gene            88697..89746
                     /locus_tag="VVR63_000102"
     CDS             88697..89746
                     /locus_tag="VVR63_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HEU6128169.1"
                     /translation="MVELGISTFGEITELEGTGQTYSHAERIRQLVAEIELADKVGLD
                     VYGIGEHHRADFAVSAPEIVLAAGAVNTKKIRLTSAVSILSSMDPIRLFQQYATIDAL
                     SNGRSEIMAGRGSFTESFPLFGYDLKDYDSLFDEKLDLLQLVNEKTKLDWQGRLTQTI
                     AGKEVYPRPVQDKLPLWIATGGHVESTVKIAQAGLPIVYAIIGGNPRYFKKLIQAYRE
                     IGSEAGHADKDLKVGAHSWGWIAEDGEQAVKDYFHPTKQVVDAISKDRPHWQELRYEQ
                     YLEQVGPNGAMFVGNPNQVAEKLIRMIEDLGLDRFMLHLPLGSMPHDQVLRAIELFGT
                     QVAPKVRAYFAMKEA"
     gene            complement(89846..93643)
                     /gene="spuA"
                     /locus_tag="VVR63_000103"
     CDS             complement(89846..93643)
                     /gene="spuA"
                     /locus_tag="VVR63_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored pullulanase SpuA"
                     /protein_id="HEU6128170.1"
                     /translation="MRKTPSHTEKKMVYSIRSLKNGTGSVLIGASLVLLAMATPTISS
                     DESTPTTNEPNNRNTTTLAQPLTDTAAGSGKNESDISSPRNANASLEKTEEKPATEPT
                     TSTSPVTTETKAEEPIEDNYFRIHVKKLPEENKDAQGLWTWDDVEKPSENWPNGALSF
                     KDAKKDDYGYYLDVKLKGEQAKKISFLINNTAGKNLTGDKSVEKLVPKMNEAWLDQDY
                     KVFSYEPQPAGTVRVNYYRTDGNYDKKSLWYWGDVKNPSSAQWPDGTDFTATGKYGRY
                     IDIPLNEAAREFGFLLLDESKQGDDVKIRKENYKFTDLKNHSQIFLKDDDESIYTNPY
                     YVHDIRMTGAQHVGTSSIESSFSTLVGAKKEDILKHSNITNHLGNKVTITDVAIDEAG
                     KKVTYSGDFSDTKHPYTVSYNSDQFTTKTSWRLKDETYSYDGKLGADLKEEGKQVDLT
                     LWSPSADKVSVVVYDKNDPDKVVGTVALEKGERGTWKQTLDSTNKLGITDFTGYYYQY
                     QIERQGKTVLALDPYAKSLAAWNSDDAKIDDAHKVAKAAFVDPAKLGPQDLTYGKIHN
                     FKTREDAVIYEAHVRDFTSDPAIAKDLTKPFGTFEAFIEKLDYLKDLGVTHIQLLPVL
                     SYYFVNELKNHERLSDYASSNSNYNWGYDPQNYFSLTGMYSSDPKNPEKRIAEFKNLI
                     NEIHKRGMGAILDVVYNHTAKVDIFEDLEPNYYHFMDADGTPRTSFGGGRLGTTHHMT
                     KRLLVDSIKYLVDTYKVDGFRFDMMGDHDAASIEEAYKAARALNPNLIMLGEGWRTYA
                     GDENMPTKAADQDWMKHTDTVAVFSDDIRNNLKSGYPNEGQPAFITGGKRDVNTIFKN
                     LIAQPTNFEADSPGDVIQYIAAHDNLTLFDIIAQSIKKDPSKAENYAEIHRRLRLGNL
                     MVLTAQGTPFIHSGQEYGRTKQFRDPAYKTPVAEDKVPNKSHLLRDKDGNPFDYPYFI
                     HDSYDSSDAVNKFDWTKATDGKAYPENVKSRDYMKGLIALRQSTDAFRLKSLQDIKDR
                     VHLITVPGQNGVEKEDVVIGYQITAPNGDIYAVFVNADEKAREFNLGTAFAHLRNAEV
                     LADENQAGSVGIANPKGLEWTEKGLKLNALTATVLRVSQNGTSHESTAEEKPDSTPSK
                     PEHQNEASHPAHQDPAPEARPDSTKPDAKVADAENKPSQATADSQAEQPAQEAQEASV
                     KEAVRNESVENSSKENIPATPDKQAELPNTGIKNENKLLFAGISLLALLGLGFLLKNK
                     KEN"
     gene            94060..94473
                     /gene="rpsL"
                     /locus_tag="VVR63_000104"
     CDS             94060..94473
                     /gene="rpsL"
                     /locus_tag="VVR63_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HEU6128171.1"
                     /translation="MPTINQLVRKPRKSKVEKSKSPALNVGYNSHKKVQTNVSSPQKR
                     GVATRVGTMTPRKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGHVKD
                     LPGVRYHIVRGALDTAGVNDRKQGRSKYGTKRPKA"
     gene            94493..94963
                     /gene="rpsG"
                     /locus_tag="VVR63_000105"
     CDS             94493..94963
                     /gene="rpsG"
                     /locus_tag="VVR63_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HEU6128172.1"
                     /translation="MSRKNRAPKRDVLPDPLYNSQLVTRLINRVMLDGKRGTAASIVY
                     GAFEQIKEATGNDALEVFETAMENIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTIARLRGEHTMQDRLAKEILDAANNTGAAVKKREDTHRMAEANRAFAHFRW"
     gene            95358..97439
                     /gene="fusA"
                     /locus_tag="VVR63_000106"
     CDS             95358..97439
                     /gene="fusA"
                     /locus_tag="VVR63_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HEU6128173.1"
                     /translation="MAREFSLEKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWNNHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPAEYLDQAQEYREKLVEAV
                     AETDEELMMKYLEGEEITNEELKAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVID
                     YLPSPLDIPAIKGINPDTDEEETRPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     QSGSYVLNTSKGKRERIGRILQMHANSRQEIDTVYSGDIAAAVGLKDTTTGDSLTDEK
                     AKIILESINVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIS
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLVESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLALKEAAKSAQPAILEPMMLVTITVPEENLGDVMGHVTA
                     RRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSASQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGED"
     gene            97543..101934
                     /locus_tag="VVR63_000107"
     CDS             97543..101934
                     /locus_tag="VVR63_000107"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HEU6128174.1"
                     /translation="MSNSFEILMNQLGMPAEMRQAPALAQADIERVVVHKISKVWEFH
                     FVFSNILPIEIFLELKKGLREEFSKTGNKAIFEIKVLSQEFSNQLLQAYYREVFSEGP
                     CASQGFKSLYQNLQVRAEDNQLFIEGSEAIDKEHFKKNHLPNLAKQLEKFGFPAFNCQ
                     VEKNDVLTQEQEEAFYAENEQIVQAANEEALRAMEQLEQMAPPPAEEKPAFDFQAKKA
                     EAKPKLDKAEITPMIEVTTEENRLVFEGVVFDVEQKVTRTGRVLINFKMTDYTSSFSM
                     QKWVKNEEEAQKFDLIKKNSWLRVRGNVEMNNFTRDLTMNVQDVQEVVHYERKDLMPE
                     GERRVEFHAHTNMSTMDALPEVEEIVATAAKWGHKAVAITDHGNVQSFPHGYKAAKKA
                     GIQLIYGMEANIVEDRVPIVYNEVEMDLLEATYVVFDVETTGLSAIYNDLIQVAASKM
                     YKGNVIAEFDEFINPGHPLSAFTTELTGITDDHVKNAKPLEQVLQEFQEFCKDTVLVA
                     HNATFDVGFMNANYERHGLPKISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALEH
                     HHMANYDAEATGRLLFIFIKEVAEKHGVTDLARLNIDLISPDSYKKARIKHATIYVKN
                     QVGLKNIFKLVSLSNTKYFEGVPRIPRTVLDAHREGLILGSACSEGEVFDAVVSQGVD
                     AAVEVAKYYDFIEVMPPAIYAPLIAKEQVKDMEELQTIIKSLIEVGDRLGKPVLATGN
                     VHYIEPEEEIYREIIVRSLGQGAMINRTIGHGEHAQPAPLPKAHFRTTNEMLDEFAFL
                     GEELARKLVIENTNALADIFEPVEVVKGDLYTPFIDKAEETVAELTYKKAFEIYGNPL
                     PDIVDLRIEKELTSILGNGFAVIYLASQMLVQRSNERGYLVGSRGSVGSSFVATMIGI
                     TEVNPLSPHYVCGQCQYSEFITDGSYGSGFDMPNKDCPNCGHKLSKNGQDIPFETFLG
                     FDGDKVPDIDLNFSGEDQPSAHLDVRDIFGEEYAFRAGTVGTVAAKTAYGFVKGYERD
                     YGKFYRDAEVERLAQGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAEWQ
                     TTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPNEIPMDDEGVMALFSGTDVL
                     GVTPEQIGTPTGMLGIPEFGTNFVRGMVDETHPTTFAELLQLSGLSHGTDVWLGNAQD
                     LIKQGIADLSTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGYIE
                     AMKANKVPEWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAK
                     AFDIKTMGAGLDAIKRRMEEISEKRKNNEASNVEIDLYTTLEIVNEMWERGFKFGKLD
                     LYRSDATEFIIDGDTLIPPFVAMDGLGENVAKQLVRAREEGEFLSKTELRKRGGLSST
                     LVEKMDEMGILGNMPEDNQLSLFDELF"
     gene            complement(101977..>102813)
                     /locus_tag="VVR63_000108"
     CDS             complement(101977..>102813)
                     /locus_tag="VVR63_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEU6128175.1"
                     /translation="FHFKHDFSCLPEIMSWDEYAFTKGKMSFIAQDFNNLNIITVLEG
                     RTQAIIRNHFLKYDRAVRCRVKIITMDMFSPYYDLARQLFPCAKIVLDRFHIVQHLSR
                     AMSRVRVQIMNQLDRKSHEYKAIKRYWKLIQQDSRKLSDKHFYRPTFRMHLTNKEILN
                     KLLSYSQDLKHHYQLYQLLLFHFQNKEPEKFFGLIEDNLKQVHPLFQTVFKTFLKDKE
                     KIVNALQLHYSNAKLEATNNLIKLIKRNAFGFRNFENFKKRIFIALNIKKERTKFVLS
                     RA"
BASE COUNT        30632 a        18935 c        22899 g        30347 t
ORIGIN      
        1 tattaagaca atatgaggag aaagatgaaa gaaaaaggat tttaggaggg ggcgcaggca
       61 gccatgccaa cggctcttgg ctatgtcagt atcggcctgg cctgtggaat tatcggtgcg
      121 ccctatgtga cacctgttga gatgggcttg atgagtctct ttgtttatgc tgggagtgcc
      181 cagtttgcca tgttggcact gattgtggtt caagctcctg tggcagctat tgctatgacg
      241 gtttttctaa tcaatttgcg tctctttttg ttgagcttac acgcatcgac ttatttccgt
      301 cataccagtc tttggcacaa tatcggtatg tctagtatct tgacagatga gacctatggc
      361 gttttgatgg gcgaattagc ccatacagat aaggtcaatc cgatgtggat gcacgggaac
      421 aatctcaaca gctatgtggc ttggtttgtg ggaacagtgg tcggaacggc tctaggtgac
      481 ctgttgccaa atccagaaat ctttggttta gattttgccc tggttgggat gtttatcggg
      541 atttttgctt cgcaattcca gatgatgcaa agacggattt ctgtccgcaa tctgctcatt
      601 atcttagcag ttgttgcagt gtccttcttt ttacttttga cagtggtgtc tcagtcacta
      661 gctgttctgt ttgcgacgct acttggttgt agcatgggga tggttttaga tggtcagtaa
      721 gtatctttta ttagcagtta ttttctctgg tcttgtgacc tggattcccc gtatgattcc
      781 cttcatcttg gtcaagtata agggcctgcc tacgattgtt gagcgttttt tgaagttttt
      841 gcctgtttcc attatctttg ccttgattct ttcaagagta gtgacaggta aggttgggaa
      901 ccttcctcaa atcaaatgac tggacttctt agcagtcttt ccaacagctt gggtagcttt
      961 tcgctaccgc aatctagtcg gtacggttct ctttggagta gtcttgattg ccgtcttgcg
     1021 tttggtcttt taaataagtc ataaagaaaa cttatcacag agatagatat catataatgg
     1081 cgtaattact ttttttctga taagattata aggtattcta ttttggagga aatgacatga
     1141 aaaaaatcgt taaatactca tctcttgcag cccttgctct tgttgctgca ggtgtgcttg
     1201 cggcttgctc aggtggtgct aagaaagaag gacaagcagc tagcaagaaa gaaatcatcg
     1261 ttgcaaccaa tggatcacca aggccattta tctatgaaga aaatggcgaa ttgactggtt
     1321 acgagattga agtcgttcgc gctatcttta aagattctga caaatatgat gtcaagtttg
     1381 aaaagacaga atggtcaggt gtctttgctg gtcttgacgc tgaccgttac aatatggctg
     1441 tcaacaatct tagctacact aaagaacgtg cggagaaata cctctatgcc gcaccaattg
     1501 cccaaaatcc taatgtcctt gtcgtgaaga aagatgactc tagtatcaag tctctcgatg
     1561 atatcggtgg aaaatcgacg gaagtcgttc aagccactac atcagctaag cagttagaag
     1621 catacaacgc tgaacacacg gacaacccaa ctatccttaa ctatactaag gcagatttcc
     1681 aacaaatcat ggtacgtttg agcgatggac aatttgacta taagattttt gataaaatcg
     1741 gtgttgaaac agtgatcaag aaccaaggtt tggacaactt gaaagttatc gaacttccaa
     1801 gcgaccaaca accgtacgtt tacccacttc ttgctcaggg tcaagatgag ttgaaatcgt
     1861 ttgtagacaa acgcatcaaa gaactttata aagatggaac tcttgaaaaa ttgtctaaac
     1921 aattcttcgg agatacttat ctaccagcag aggctgatat taaataattt cttgaaatca
     1981 tccattctga gtaagatggg tgatttctca gtttttaggg atatagtttt aaactatata
     2041 tctgattatc taataacaat ttgtgaaatc aaacaaattg tgagatacta gtacggtatt
     2101 atttttaagg agaaagaatc atgaaaatca aaaaatggct tggcctagta gcccttgcta
     2161 cagtcgcagg tttggctctt gcagcttgcg gaaactcaga aaagaaagca gacaatgcaa
     2221 caactatcaa aatcgcaact gttaaccgta gcggttctga agaaaaacgt tgggacaaaa
     2281 tccaagaatt ggttaaaaaa gacggaatta ccttggaatt tacagagttc acagactact
     2341 cacaaccaaa caaagcaact gctgatggcg aagtagattt gaacgctttc caacactata
     2401 acttcttgaa caactggaac aaagaaaacg gaaaagacct tgtagcgatt gcagatactt
     2461 acatctctcc aatccgcctt tactcaggtt tgaatggaag tgccaacaag tacactaaag
     2521 tagaagacat cccagcaaac ggagaaatcg ctgtaccgaa tgacgctaca aacgaaagcc
     2581 gtgcgcttta cttgcttcaa tcagctggct tgattaaatt ggatgtttct ggaactgctc
     2641 ttgcaacagt tgccaacatc aaagaaaatc caaagaactt gaaaatcact gaattggacg
     2701 ctagccaaac agctcgttca ttgtcatcag ttgacgctgc cgttgtaaac aataccttcg
     2761 ttacagaagc aaaattggac tacaagaaag cacttttcaa agaacaagct gatgaaaact
     2821 caaaacaatg gtacaacatc attgttgcga aaaaagattg ggaaacatca cctaaggctg
     2881 atgctatcaa gaaagtaatc gcagcttacc acacagatga cgtgaaaaaa gttatcgaag
     2941 aatcatcaga cggtttggat caaccagttt ggtaataaga aacagggagg tgggagagag
     3001 aattccacct cttgcttttg tatagagcac ggagtgtaaa gaagactatt cgttcataga
     3061 aaggtagaga gaatatggtt tttcctagcg aacaagaaca gattgaaaaa tttgaaaagg
     3121 atcatgtagc ccagcattat tttgaggttt tgcgtacctt gatttctaag aaatcagtct
     3181 ttgcccagca ggttggactc aaggaagtcg caaattatct gggtgagatt ttcaagcgtg
     3241 ttggagctga agtggagatt gatgagagct atacagcgcc ctttgtcatg gcacatttca
     3301 agagttcgcg tccagatgcc aagaccttga ttttctataa ccactatgac actgtgccag
     3361 cggatgggga tcaggtctgg acagaggatc cttttacgct ttcggtccgc aatggcttca
     3421 tgtatgggcg tggagttgat gacgacaagg gtcatatcac agctcgcttg agtgctttga
     3481 gaaaatatat gcagcaccat gatgatttac ctgtcaatat cagctttatc atggagggag
     3541 cggaggaatc ggcttcaaca gacctagata agtatttgga aaagcatgca gacaaactcc
     3601 gtggggcgga tttgttggtc tgggaacaag ggaccaaaaa tgccttggaa cagctggaaa
     3661 tttctggtgg caataagggg attgtgacct ttgatgccaa ggtaaaaagc gctgatgtgg
     3721 atatccactc gagttatggt ggtgttgtgg aatcagctcc ttggtatctc ctccaagcct
     3781 tacagtctct tcgtgctgcg gatggccgta tcttggttga aggcttgtac gaagaagtac
     3841 aagagcccaa tgaacgagaa atggccttgc tagaaactta tggtcaacga aacccagagg
     3901 aagttagtcg gatttatgga ttggagttgc ctctcttaca ggaggagcgg atggcctttc
     3961 taaaacgttt ctttttcgat ccagcgctta atatcgaagg aatccagtct ggttatcaag
     4021 gtcagggtgt taagactatt ttacctgcag aagccagtgc caagctagag gttcgtctgg
     4081 ttccgggcct agaaccgcat gatgttctgg aaaaaattcg gaaacagcta gacaaaaatg
     4141 gctttgataa ggtagaatta tactatacct tgggagagat gagctatcga agcgatatga
     4201 gcgcaccagc cattctcaat gtgatcgagt tggccaagaa attctatcca cagggcgttt
     4261 cagtcttgcc gacgacagcg gggacaggac ctatgcatac ggtctttgat gccctagagg
     4321 taccaatggt tgcattcggt ctaggaaatg ccaatagccg agaccacggt ggagatgaaa
     4381 atgtgcgaat cgctgattat tacacccata tcgaattagt agaggagctg attagaagct
     4441 atgagtagag atattatcaa gttagatcag atcgatgtga cttttcacca aaagaagaga
     4501 accatcacag cggttaagga tgtgaccatt cacatccaag aaggggatat ctacggaatc
     4561 gttggatatt ctggagcagg aaaatcaacc cttgtacggg tgattaatct tttgcaaaaa
     4621 ccatctgcag ggaaaattac cattgacgac gatgtgattt ttgacggcaa ggtgaccttg
     4681 acggcagagc agttgcgtcg taaacgtcaa gatatcggga tgattttcca gcattttaac
     4741 ctgatgagcc aaaagacagc agaggagaat gtagcctttg cccttaaaca ctctggactc
     4801 agcaaggaag aaaagaaggc taaagtagct aagttgttgg acttggttgg tttggcagat
     4861 cgtgctgaaa actacccttc acaactatct ggagggcaaa aacagcgtgt ggcaattgcg
     4921 cgtgccttgg ccaatgatcc aaaaatcttg atttcagacg agtcaacttc tgcccttgac
     4981 cctaagacaa ccaagcagat tttggccttg ttgcaagatt tgaaccaaaa attaggattg
     5041 acagttgtct tgattacgca tgaaatgcag attgtcaaag acattgccaa ccgtgtggcg
     5101 gttatgcagg atgggcattt gattgaagag ggaagtgtcc ttgaaatctt ctcaaaccct
     5161 aaacaacctt tgactcaaga ctttatctca acagccacag gtattgacga agccatggtc
     5221 aaaatcgaga agcaagaaat cgtggaacac ttgtctgaaa acagtctctt ggtgcaactc
     5281 aagtacgctg gagcttcaac agacgagcca cttttgaatg aattgtacaa gcattaccaa
     5341 gtaatggcta atattctcta tgggaatatc gaaattctcg atggtactcc tgttggagaa
     5401 ttggtggtgg tcttgtcagg tgaaaaagca gcgttggcag gtgcccaaga agccattcgt
     5461 caagcaggtg tacaactaaa agtattgaag ggagtacagt aagatggaat cattgattca
     5521 aacctattta ccaaatgtct ataaaatggg ttgggctggt caggcaggct ggggaacggc
     5581 tatctactta actctttata tgacagttct ttccttcatt atcggaggct tcttggggct
     5641 agtggcaggt ctctttctcg tcttgacagc gccaggtggt gtcttggaga ataaagtcgt
     5701 attctggatt ttagacaaaa ttacctcaat ttttcgtgcg gttcccttta tcatcctctt
     5761 ggcaatcttg tcaccacttt ctcacttgat tgttaaaaca agtatcgggc caaatgcagc
     5821 ccttgtccca ctttcttttg cagtctttgc cttctttgcc cgtcaggtgc aggttgtctt
     5881 ggctgaattg gatggcggtg tcattgaggc ggctcaagcg agcggagcga ctttctggga
     5941 catcgtgggt gtttacctat cagaaggtct tccagatttg atccgtgtga cgactgtgac
     6001 cttgatttcc cttgttgggg aaacagctat ggccggtgcg gttggagctg gtggtatcgg
     6061 taacgtagcc atcgcttatg gatttaaccg ctacaatcac gatgtgacca tcttggcaac
     6121 cattattatc attttgatta tctttgcaat ccaattcttg ggagatttct tgactaagaa
     6181 attgagccat aaataaaaaa gagccgcgtg gctcttttta actgatcaga ttttctgtgc
     6241 aaatttttta ctcaaggctt gtccaatcaa ggcacccact agggctccga tgacaatact
     6301 tgcgataaat agaaggacag ttccagggtt tggagcgacc atgatacggt cgatatattc
     6361 ttgggatttt cctcttgcca gaagagtagc catataggct ttgggcgcaa tccacataag
     6421 caagattggt cctgttgtac taaaggcgaa aataatgaaa gaaaggaagt tctttgtttt
     6481 gtccttgtat tttcctaaat gagctacttc atctgctagg aggccacaga taattccagg
     6541 aaggaaggaa ccagcaccgt gtttagttcc caagaaaaag agggcaatga caaggccgat
     6601 agtggtaatg gctccaaagc gcggaacttt tgcgactagg atcatataga cgctaccgcc
     6661 gacaagggca gtaaaggcag gcgcataaaa catgtttcca gtttggtcaa agagattgcc
     6721 caaaaggaca ccaatcccca tgcagaggaa gtaaagaact gcaaaaagca gtgtagttaa
     6781 gatagatttc ttcatgaatt gtctcctgat aattttttca caattctcat tgtaccacgg
     6841 tttggtggga ttgtaaatgg atactagaag tttttgaaaa cgcttgaaat atgatataat
     6901 ggtttcatag ttatttttag gggaatatca tgggtagatt tttagacttt gtctttaatc
     6961 gtttcttttt agggatgatt gcgacagcct tcttttggct attaacttta gcaggaggga
     7021 ttatccttgg tctagcgccg gctagtgcca ccttgatgag cttatatgca gaacatggtt
     7081 atagctttcg ggaatacagt ttgaaggagg cttggtctct ttacaagcaa aattttgtct
     7141 caagcaacct gattttctat agctttttag gtgtgggtct agttttgacc tatggtttgt
     7201 atctcttggt gcaattgcct catcagacca ttgttcattt gattgcgacc cttttgaatg
     7261 tcctagtagt tgccctgatc tttttggctt atacagtatc tttaaaatta caagtttatt
     7321 ttgccttgtc ctatcgaaat agtctcaaat tatccttgat tggcatcttt atgagtctag
     7381 cagctgtggc caagattctc cttgggactg tgctacttgt agcaattggt tactatatgc
     7441 ctgccctgct attttttgta ggaattggga tgtggcattt ctttatcagt gatatgttgg
     7501 aacctgtcta tgaaatcatc catgaaaaat tggcgacaaa atagaatgaa gcagttttgg
     7561 ctacatacgc ttctaagaac ctatagttca gtgatgatca ttatcattgc gagttttgca
     7621 atcttactct cttacgctga ctgggattca cgtgaaaagg aagcccagag agtagcccag
     7681 cgtgtaactg ctagaacagt gagtgaaatt gaatattacc atagagagtc aacccagata
     7741 gctcaggctt tagttgaaaa ccaagctcgt attgagggaa tctataaata ctttagtctt
     7801 agcatgccag actattttta ctggcaatta gagcggaaag cttcgcctta tatatcagtc
     7861 tctctgtatg aaaatgttga tgacctctat gttcgaaatg attttgtaac tggagtggcc
     7921 attgcttttc aagattacaa ggaagtctat gtttctacta aagacaaacg tagtggagaa
     7981 aaaatcaggg ctgaggattt caaaccagca ggaaatagtt ttgccattcc ggtgtcagat
     8041 ccagtgtcag atcaagattt aggagtgatt tacatctcct tggatcctgc tgttttatac
     8101 catgccattg ataatactag aggtcatact ccgatggcag taacagtgac ctcacctttt
     8161 gatacggaga tttttcatat tggtgagaca gttgataagg agagtgaaaa ttggctagtt
     8221 ggcttaactt ctcatggata tcaggttcag gtggcagttc ctaaaaactt tgttttacaa
     8281 ggaacagtga ctagctctgc tttgattgtg ggtttgagcc ttctctttat tgtcattctt
     8341 tatctgactt tgaggcagac ttttgctaat taccaaaagc aggtagtgga tttagtagaa
     8401 tccattcaag tcattgctca aggcgaagag gggcgtcgga ttgacatttc cgagaaagat
     8461 caggaattac tcctaatcgc ggagacgacc aatgatatgt tggatcgatt ggaaaagaat
     8521 atccatgata tttaccagtt agagcttagt caaaaagatg ccaatatgcg agccttgcag
     8581 gcgcaaatca atcctcattt tatgtataat acgctggagt tcttgcgcat gtatgcagtt
     8641 atgcagagtc aagatgagtt ggcagatatc atttatgaat tcagtagtct cttgcgtaac
     8701 aatatttccg acgaaagaga gaccctcctc aaacaggaat tagaattttg ccgtaaatac
     8761 agctatctct gcatggttcg ctatcccaag tccattgcct atggtttcaa gatagatcca
     8821 gagttagaga atatgaagat tcccaagttt accttgcaac cgctggtaga aaactatttc
     8881 gcgcatggtg ttgaccacag gcggacagat aatgtgatta gcatcaaggc tcttaaacag
     8941 gatggttttg tggaaatttt ggtggtcgat aatggtagag gaatgtcggc tgaaaagttg
     9001 gcaaatatcc gagaaaaatt aagtcagaga tattttgaac accaagccag ctacagtgat
     9061 caaaggcagt ctatcgggat tgtcaatgta cacgagcgtt ttgtgctcta ttttggagac
     9121 cgctatgcca ttactataga gtctgcagag caagccggtg ttcagtatcg tattacaatt
     9181 caagatgagt agaaagggag aaaatgtata aagtattatt agtagatgat gagtacatgg
     9241 tgacagaagg tctgaagcgt ttgattccct ttgataagtg ggatatggag gtcgtcgcaa
     9301 cagtcagtca tgccgatgaa gctctagaat atgttcagga aaatcctgtc gatgtcatca
     9361 tttccgatgt caatatgcca gacaaaacag ggcttgatat gattcgggag atgaaagaga
     9421 tcttaccaga tgctgcctat atcctgctct caggttatca ggagtttgat tatgtaaaaa
     9481 gagcaatgaa ccttagtgtg gtggactatt tggtcaaacc tgttgataag gtagagctgg
     9541 gaaatctgct ggagaagatt gcaggtcagc tcggcgagag agggaagaaa agtcagactc
     9601 ttagtcaaga attagacgag gctggatttg ttagttattt aggggataag gagaattggt
     9661 ggataggtct atccaaggaa aaacaaggtt ccttcaccat tccctactat gtcttgggcc
     9721 aggactggca gattttcatt tctgaccaac ccctagatgg tttagtcgtt acaccttttg
     9781 aagctcctta tcaagaacac tttgaacgct ggaagctgaa tgctgagaaa accctctttt
     9841 acggttctgt aaatttgcag cagtctgaga gtctctttgc ctattacgaa ccgatttata
     9901 gggttatcat tcagggaaat ctcaatcaaa tcgtagaaga gttaaatctc ttggagaagg
     9961 tagttcttga aaatacgccg cgtgttccga ttactaaaca gctttttatt cagtttgtca
    10021 tggatgtttt ccatttattt gaacatctca aagctgatga cctgacagac atcgtcaaaa
    10081 ccattcatgc tattcaatcc ttcgatgaat tggttcctta tatcaaggaa actctgacca
    10141 gctttttcgg tcaataccgt atgaatgaaa atgtggtcag tgtgctggaa gtcattggtc
    10201 gtgattacca aaaagagctt tccctcaagg atatcagtaa ggatctcttt atcaatcctg
    10261 tctatctagg gcagttgatt aagcgtgaaa ccgattcgac ttttgcagag ttactaaaca
    10321 aacaacgtat taaggctgcc caacaacttt tgctttcaac tagtgacagc atcgaagata
    10381 tttgttatgc tgttggttac agtaaccttg gatatttcta taaagttttc cgaaaattgt
    10441 gcggaaaatc gccaaaagcc taccgaaaac aggtagaaac tatactataa gatttgtatt
    10501 cctttacaaa atgtgctata atataaatat tattatcagg aggttctatc atgaaaaaga
    10561 aaccaattta tctatgggtc ttgctaatct tgtctgccct tatttcagtt ccgtctctgt
    10621 ttggaattgt gagtcccttg cctagtaaag aagcccttcg tactgctcag aaacaagttg
    10681 caggggtcaa tgctcagcaa ttagaagacc agcttaatta tacctataga gtagcagaag
    10741 catctcattc tatttttaat gttgctttga ttgtgctatc tactatttta gtggtcgtag
    10801 cgattgtctt ccttgttcgt aaaaatttgc aatatgcaaa ctatacttac gttggctatg
    10861 ttttgttagc tattattggt tcgatttatg gctatgttgg tttacaagac gctgtgcagt
    10921 tggttcaaga tgagagcatg cgtttgacag tgagtattgg ttcaaaagct gttagcattt
    10981 tctatatcgt catcaatgtt ctcttcctag cccttgtctt ctataagatg tggcgacaac
    11041 agaaagcctt ggcagaagaa gaggaaacag aagagcttac ctaagtattg acaaaaaaga
    11101 actatcaaga tacaatcttg gtagttgttt tttgattata gataaaatca tggaggtaca
    11161 tatgaagaca atttctttag tttatattag tttgagtggc aacactgaaa gttttgtgac
    11221 gcgcttgaaa gactatctct tgtcccagta caaagggatt gaggttcaaa agattcatat
    11281 caaggatttg gtcaaggaag gcaaaaattt ctatgaaatg gaccatccct atgtcgcttt
    11341 tttgccgacc tatctcgaag gtgggaatgg cgtggataac ggagatgttg agattttgac
    11401 gacaccggtg ggagatttta ttgcctatgg taacaatgct agtaagtgtt ttggtgtggt
    11461 tgggtcagga aatcgtaact ttaataacca atactgccta acagccaagc aatacagtca
    11521 acgctttggc ttccctgtat tggctgactt tgaaatgcga ggcatgctgg aagatatcaa
    11581 acatgtcgca gctattatcg cagatttgta tgagttggaa aaggagaatt aatactcaat
    11641 gaaaatcaaa gagcaaacta ggaagctagt cgcaggttgc tcaaagcaca gctttgaggt
    11701 tgcagataga gctgacgtgg tttgaagaga ttctcgaata gtataaagtt cttataagat
    11761 gtggttgaag ttgttcaact gttttttgag tataaacagt ctttaagaac gtaaaaaagc
    11821 ataagttcag gtcttcaaaa ccttgttctt atgcttttta tcatagaaat atttgctgaa
    11881 ttttctcttg aaatgaaacc ttatcttcat ctcgcgcttg tcccttaccc tgcttttccg
    11941 attgcgagtg cgtagataaa gaagatggcg aagccaaaga ggaaaatcaa tcccgcaatg
    12001 gcaaggtgtt tgagccaaga aggaagattt ttgttttcac gtgttaccaa ggcgtaattc
    12061 aaaagagcaa agaaaggtgt tgtcaggaaa gagccaatca tggcaaagcg gagcatggtt
    12121 gaaacctgac cagcgaagaa cttgataatg acgataccga tgatagcagt gatggtcatc
    12181 cagatgttca aagatttacg attgtcctct ttttgactga ttagcagtcg gagagattcc
    12241 tgattaacgc gagaatagcc atcgataaca gttataactg ttccaaagat acagaggaag
    12301 gcaataaagg taatcaagta acgggaccat tcgccaagaa cagaggcata catgcccacg
    12361 aattgagaga tgtatttggc tgaagcagct tcaaccgcct gccctgtagg atactgaatc
    12421 agtgctccca gtgccacaaa gaagacggct aggatagctg ttccaatata accagtgtta
    12481 aagtcaaaca gagcgtcttc tgtgttaaag ttgacggtct ttctcttttc agctgaccaa
    12541 agtgaattga tggctgaaat ttcaatagga gccggcatcc atcctaggag ggagacgatg
    12601 aagggcagag ctgccatttg ccaaggtgtc ttctcgacaa aatcagaact gtattctgga
    12661 tgcttgaccg ccgcaatgat aactgcaaga acagtcgcaa tggttaaggc agacataatc
    12721 catttgacca tgccgtctaa aagtttgtag cctccaaaga gtagcatagc ccaaatgatt
    12781 gcaacgagaa tgagggacca ctgagtaatg ctaagtccaa tcattgggaa ggcactggcg
    12841 atgatagctg agcacagaat ggcaacacca gccgtgttga ccatagccga aaagacattg
    12901 agaataaaga aaatccagag atagagtttt cctttttcgg cataaccttc aaccaaagtc
    12961 tttccagtat cagctgtgta ttcagcacca aaacggaaaa atggatattt aaagacattg
    13021 gctaagatga ccaagagaag tagagaccaa ccgtaagaac cgccagcttg agttgaggat
    13081 acaatgtggg aacctccaac agcggcagtt gccattagga ttccaggtcc cattgctttt
    13141 agcttgcttg cccaggttga ttgatttaag gaaatagctt gcgacatgat aaatactcct
    13201 ttttgaattt tcagaataat ctgtatatgc aatctatatt ctacaaaaaa ttttggaaaa
    13261 atgcaagaat attttgaaaa aagatagaaa atttacaaag aaaatctgaa ataactgtta
    13321 tgatatagca gattgaaact agaatagtac acttttgctt ctaaaacatt gttagaaatc
    13381 gatttgactg tcctgattga tttatcctgt tcttatttca tttcactata gtaaggtgca
    13441 gcaggataaa gcaaaaccga gaagtttctt tctcggtttt gcttattatg aggttcctat
    13501 tttctatgct ccaagagttg attgatgtga tctacttttt tagcctctct tttatagaga
    13561 atagcccaga tgatgagata gacaatcgca aactcgataa tgagctggag gtagaaaatc
    13621 cagtggaagg ggaaccaacc agcaagagtt gctagtggga caaagccagc cagcataagg
    13681 aagaaatgag tcagagtggc acgaagcatg ctccagtcac ggctgaataa gcggttgcca
    13741 aagttgaaga gcataccgat ggctgcccag ataagtgtgc agtagagcaa gaccagggca
    13801 ccgtgaacct gatgctgatc catcacttgg ccgatgagag agtagggatt tagtggtgcg
    13861 taggtatttg gtgcataaat gagtgaaaag aggatggaga ggatgaggcc gataagaaca
    13921 ccggcagctg catcgtgaaa tacttgtttt ttcatagttc taatttctcc ttgatggttt
    13981 ttagataacg gcgtgaagag taggtgaagc tttcgttttt caagaaaatt tctaccagac
    14041 cgtttggcgt gagcttgagg tgagagatgg aatcgatatt gatgatttct gattgggaaa
    14101 tttggataaa attgcttggc aagagtttaa gaacctgata gagtcgcaaa tcaatgctgt
    14161 aggtctgact cgcggtttct gctagaacct tccgattctc gatatagaag cgctgaatct
    14221 tgccaatctc aactagatag acctgatcat cgatttttcc tttgattttt tctctttggt
    14281 ccagattttc tgcgaactcg atgactttct ggactttttc ggtttcttga ggtgcttgga
    14341 caatcagctt ttcctcctcg taagtctcac taatctgtag ttctactttc ataaatttct
    14401 ctccttgttt ttcatacaaa attaatctca cttcttgtac acctttatta atactcttca
    14461 aaaatctctt caaaccacgt cagcgtcgtc ttgccgtagg atagttgttg actttgtcag
    14521 ttttatctac aacctcaaaa cagtgttttg agctgtctgc gtctagcttt ctagtttgct
    14581 ctttgatttt tattgagtat accactattt tactccctct ggcaagggac tttgtctatg
    14641 tggagggatt gggctcctat gtggtggagt ttttctgttc tttctgaaat atggtataat
    14701 agcactaatt aatttctagg aaaatagata cagaaagggg ctgaaagatg tctcatatta
    14761 ttgaattgcc agagatgctg gcaaaccaaa tcgcagctgg ggaggtcatt gaacgtcctg
    14821 ccagtgtggt taaagagttg gtagaaaatg ccattgacgc gggctctagt cagattatca
    14881 ttgagattga ggaagctggt ctcaagaagg ttcaaatcac ggataacggt catggaattg
    14941 cccacgatga ggtggagttg gccctgcgtc gccatgcgac cagtaagata aaaaatcaag
    15001 cagatctctt tcggattcgg acgcttggtt ttcgtggtga agccttgcct tctattgcgt
    15061 ctgttagtgt cttgactctg ttaacggcgg tggatggtgc tagtcatgga accaagttag
    15121 tcgcgcgtgg gggtgaagtt gaggaagtca tcccagcgac tagtcctgtg ggaaccaagg
    15181 tttgtgtgga ggatctcttt ttcaacacgc ctgcccgtct caagtatatg aagagccagc
    15241 aagcggagtt gtctcatatc attgatattg tcaaccgtct gggcttggcc catcctgaga
    15301 tttcttttag cttgattagt gatggcaagg aaatgacgcg gacagcaggg actggtcaat
    15361 tgcgccaagc aatcgcaggg atttacggtt tggtcagtgc caagaagatg attgaaattg
    15421 agaactctga cctagatttc gaaatttcag gttttgtgtc tttacctgag ttgactcggg
    15481 ctaaccgcaa ttatatcagc ctcttcatca atggccgtta tatcaagaac ttcctgctca
    15541 atcgtgctat tttggatggt ttcggaagca agcttatggt tggacgtttt ccactggctg
    15601 tcattcacat ccatatcgac ccttatctag cggatgtcaa tgtgcatcca actaagcaag
    15661 aggtgcggat ttccaaggaa aaagaactga tgaccctggt ttcagaagct attgcaaata
    15721 gtctcaagga acaaaccttg attccagatg ccttggaaaa tcttgccaaa tcgaccgtgc
    15781 gcaatcgtga gaaggtggag caaactattc tcccactcaa agaaaatacg ctctactatg
    15841 agaaaactga gccgtcaaga cctagtcaaa ctgaagtagc tgattatcag gtagaattga
    15901 ctgatgaagg gcaggatttg accctgtttg ccaaggaaac cttggaccga ttgaccaagc
    15961 cagcaaaact gcattttgca gagagaaagc ctgctaacta cgaccagcta gaccatccag
    16021 agttagatct tgctagcatc gataaggctt atgacaaact ggagcgagaa gaagcatcca
    16081 gcttcccaga gttggagttt ttcggacaaa tgcacgggac ttatctcttt gcccaagggc
    16141 gagatggact ttacatcata gatcagcacg ctgctcagga acgggtcaag tacgaggagt
    16201 accgtgaaag cattggcaat gttgaccaga gtcagcagca actcctagtg ccctatatct
    16261 ttgaatttcc tgcggatgat gccctgcgtc tcaaggaaag aatgcctctc ttagaggaag
    16321 tgggcgtctt tctagcagag tacggagaaa atcaatttat tctacgtgaa catcctattt
    16381 ggatggcaga agaagagatt gaatcaggca tctatgagat gtgcgacatg ctccttttga
    16441 ccaaggaagt ttctatcaag aaataccgag cagagctggc tatcatgatg tcttgcaagc
    16501 gatctatcaa ggccaatcat cgtattgatg atcattcagc tagacaactc ctctatcagc
    16561 tttctcaatg tgacaatccc tataactgtc ctcacggacg tcctgttttg gtgcatttta
    16621 ccaagtcgga tatggaaaag atgttccgac gtattcagga aaatcacacc agtctccgtg
    16681 agttggggaa atattaaaag tataaaaaag tctgggaaaa attttcaaaa tcagaaaaac
    16741 gcataaaatc aggtgttcaa aaaccttgat tttatgcgtt ttatcatgga aatagttact
    16801 tcatgttttc ctaattcttt tcgaaactct ttttaaacca cgtcagtttt atcagtaatc
    16861 tcaaaacagt gttttgagct aattttgcca gttttgtctg taacatcgaa gttgtgtttt
    16921 accactctgc gactggtttc ctagtttgct ctatgatttt cacagagtat taaattgcga
    16981 ttttgccaag tttctttatt cgtctaaaag tagagtctgt tctatgcgtc taatgtacga
    17041 attaggttga ccatttcaat agctccttgt gcacactcag aacccttatt tcctgctttg
    17101 gtaccagctc gttctatggc ttgttcaatt gtatctgtcg ttagcacacc aaacataaca
    17161 ggaatttcgc tatttaaact gatttgggcg attcccttag atacctcgct acatacataa
    17221 tcataatgac ttgtattccc tctaatgaca gctcccaagc agataattgc atcatatttt
    17281 ttactttttg ccatttttga tgcaatcagt ggtatttcaa aagctcctgg aacccaggct
    17341 acctctatat ctttctcgtt tacattctct cttttgagat tatctagtgc tccagataat
    17401 aattttgaag ttataaattc attaaatctc gctacaacaa tacctatttt aatattgttt
    17461 gctactaaat taccttcata agtgttcatt tatttttcct ccatatttaa aatgtgaccc
    17521 attcgatttt tctttgtttc taaataaaaa ctatcgtaag gattggcttc tatttcgatt
    17581 gatattctac tggaaatggt aattccatat ttttctaact gttcaacctt gtcaggatta
    17641 tttgtcagta aatgaagtga ctgaagtccc agatctttaa gcatttgtgc tccaatatga
    17701 tattctctta aatcaccttc aaagcctaat gcaagattgg catcaagcgt atccatgcct
    17761 tgatcttgta aatgataggc ttttaattta ttgataagtc caattcctcg tccctcctgt
    17821 cgcaagtaaa gtaagacacc cgaaccattc tcaacaatca ttttcatagc tttatcgaat
    17881 tgctgtccac aatcgcaacg taaagagcct aaaacatctc ctgttaaaca ttcggagtgg
    17941 acccgacata atacattggc ttcatcctct atgtttccca taataagagc aagatgatgt
    18001 tccccattta gtttatctat atagctaatt gctttgaaat taccgtatct agtaggcata
    18061 ttgacagttg aaactcgttc taccagctga tcatatactt ttctatattc ttgtaattct
    18121 ttgatggtaa ttagtggaat gttgtgtttc ttcgagaact gaattaaatc atctgttctc
    18181 atcattttgc catcatgatt cattatttca caacataggc cacactcttt tagtccagct
    18241 aattttaata aatcaacagt tgcttctgtg tgtccatttc tttctagaac accacctttt
    18301 tttgcaatta aaggaaacat gtgtcctggc ctgcgaaaat cagagggtgt tatatcttca
    18361 gctacacaca tacgtgcggt cagtcctctt tcctcggcag aaatacctgt ggtcgtttct
    18421 ttataatcaa ttgaaactgt aaaagcagtc ttatgattat ctgtattgtt ttcaaccata
    18481 ggtgaaagca ttaattgatt agctaaactt tcgctcatag gcatacaaat taatcctttg
    18541 gcataagtag ccataaaatt aacattttct gttgtagctg cttgtgcaga acaaattaag
    18601 tctccttcat tttctctatc cttgtcgtct ataacaagaa caagtcgtcc cttctgcaat
    18661 gcttctaatg cttcttgtat ttttcgatat tccattgact gattatcctt tctgctaaaa
    18721 tccattttga tataatagtt ccttagatat ttctgatttt ggagagttat ccatcagttt
    18781 ttgcacatat ttacctaaga tatcattttc aagatttact gtattcccga cttgtttact
    18841 tttaagaatg gtttgttcca aggtatgagg gataacagat actgaaaagt ttactttgga
    18901 gactttagcg acagtcagac taatgccgtc aattgtaata gatccttttt caactattaa
    18961 atctaaaatt tctttttgtg tgttgatttg ataccataca gcattatcat ctttttttat
    19021 tgacgagatt tttcctgtac catcaatgtg tcctgtaacg acgtgacccc caagtcgacc
    19081 gttgacagat aaggctcttt ctagattcac ctcacttcca tgttttaata gagtaagagc
    19141 tgttcgactc catgtttcat tcattacatc aactgtaaag gattgatggt tgaaatgagt
    19201 aactgtaaga cagataccat ttactgctat actatcgcct aaatggatat ccgttaatat
    19261 ttttgaggct ttaattgata gtttacaatt acgagagtct ttctgtattc tttcaacttt
    19321 tccgatttct tcaattattc ctgtgaacat ggataaatca cttcactttc tatgagatag
    19381 tcatttccta tttgagaaaa agcataaggt ttcaatctaa tagcgtcatt tggcaaagaa
    19441 atgccttcac ctccgacagg aaacttggca ctgcctccaa aaatttttgg tgcaatatat
    19501 attttcagct catcaacaat ttgttgttcc aaagcactcc aattcattag actgccccct
    19561 tctagaacta ggctatcaat ctgcatgttt cctagatgtt gcattaaact cgataagtct
    19621 atatgattgc cttttttctt tatggaaagt atttcacagc catgattttg atatagcttc
    19681 attttatttt tgtcttcaga ggaagtggca atgtaagttt taatatcatt tgctgttttt
    19741 acgattttag aggtaagagg agttcgtaaa tgtgtatcgc atatgatacg gataggattt
    19801 ttcctttcct ccaatctaca tgtcagcaaa ggatcgtctt gaataacagt attgactccc
    19861 accataattg cactaacatg gtgtcgtaac tgatgcacat gctttcttgc ttcttcttca
    19921 gtaatccatt tggattgatt tgttttagtg gctatttttc catccattga cattgcatat
    19981 ttcataaaaa catagggtac atgctgggta atatactttc taaaactttt tattaagtta
    20041 agacactcat tttctaaaat tccaacagta acttgaagat tattttcctc aagtatcttt
    20101 actccttttc cagatacaat aggattacag tctaggcttc caatgactac tcttgtaata
    20161 ccactatcga ttatagcatc tatacaggga ggtgttttcc cgaagtgaca acagggttca
    20221 agtgttacat aaagcgtcgc tccgacaggg gattctctac agtttttaag agcatttctc
    20281 tcagcatgtg ggccaccaaa aaactcatga taaccttgtc cgatgatgtg attatctttt
    20341 acaataactg cgccgaccat aggattggga ttgacgtaac cagccccttt ttgtgccagt
    20401 tttattgcta atttcatata ttttgaatcg ctcatctcac tacctccaaa aaaatatacc
    20461 ttgaataggg gactactcaa ggcatacaaa agaaaactta tgcgattaac aaaaatactc
    20521 tgaaatgaca agtaatcatt tcagagcacg caaaaagcac aaatatactt ttatcttctt
    20581 tcatccagac tatactgtcg gctttggaat ttcaccaaat catgcctttc ggctcgtggg
    20641 ctataccacc ggtagggaat tgcaccctgc cctgaagata gttattcaat tacagatgat
    20701 tatagtactt aattttgaat atgtcaacag ataaataccg attgtttttg atatactgta
    20761 tttgtgataa tcgattctcg ctcctcggat aaagaaaata tgatatacta gataaacgaa
    20821 ataagagaga aggaatacta tgtacgcata tttaaaagga atcattacca aaattactgc
    20881 caaatacatt gttcttgaaa ccaatggtat tggttatatc ctgcatgtgg ccaatcctta
    20941 tgcctattca ggtcaggtta atcaggaggc tcagatttat gtgcatcagg ttgtgcgtga
    21001 ggacgcccat ttgctttatg gatttcgctc agaggatgag aaaaagctct ttcttagtct
    21061 gatttcggtc tctgggattg gtcctgtatc agctcttgct attatcgctg ctgatgacaa
    21121 tgctggcttg gttcaagcca ttgaaaccaa gaacatcacc tacttgacca agttccctaa
    21181 aattggcaag aaaacagccc agcagatggt gctggacttg gaaggcaagg tagtagttgc
    21241 aggagatggc cttcctgcca aggtcgcagt gcaagcaagt gctgaaaacc aagaattgga
    21301 agaagctatg gaagccatgt tggctctggg ctacaaggca acagagctca agaaaatcaa
    21361 gaaattcttt gaaggaacga cagatacagc tgagaactat atcaagtcgg cccttaaaat
    21421 gttggtcaaa taggagcaga gcatgacaaa acgttgttcg tgggtcaaga tgaccaatcc
    21481 gctctacatc gcctatcatg atgaggagtg gggccagccc ctccatgatg accaagcatt
    21541 gtttgagttg ttgtgtatgg aaacctatca ggcaggcctg tcttgggaaa cggtgctcaa
    21601 caaacgccaa gctttccgag aagcatttta tggctatcaa attcaagcag tcgcagagat
    21661 gaccgacact gaattggaag ccttgctgga gaatccagcc atcattcgaa atagagccaa
    21721 gatttttgct acacgcgcta acgcccaagc ctttctacga ctacaggaag aatatggctc
    21781 ttttgatgcc tatctttggt cttttgttga ggggaaaatt gtcgttaacg atgttcctga
    21841 ttatcgccaa gcgccagcta aaacaccctt atctgagaaa ttagccaaag atctcaaaaa
    21901 acgaggcttc aagttcacag gcccagtcgc cgtattgtct tttctacagg ctgcagggct
    21961 agttgatgac cacgagaatg attgtgagtg gaaaggtctt aaatgatgtc taacaaaaat
    22021 aagggaattc tgatttttgc gattctctat acagtcctct ttgtgtttga tggcgttaaa
    22081 ttgctggctt ctttaatgcc atctgtcatt gcaaattatc ttgtttatgt agttttagct
    22141 ttatatggct ccttcttgtt caaggataga ttgatccaac aatggaagga gattagaaag
    22201 actaaaagaa aattcttctt tggcgtctta acaggatggc tctttctcat tctgatgact
    22261 gttgtctttg aatttgtatc agagatgttg aagcagtttg tgagactaga tggacaaggt
    22321 ctaaatcagt ctaatattca aagtaccttt caagaacaac cactactgat agctgttttt
    22381 gcttgtgtca ttggacctct ggtagaagaa ttatttttcc gtcaggtctt attgcattac
    22441 ttgcaggaac ggttgccagg tttactaagc attattctgg taggacttgt ttttgctctg
    22501 actcatatgc acagtttggc cctatcagag tggattggtg cagttggtta cttaggtgga
    22561 ggccttgcct tttctattat ttatgtgaaa gaaaaagaga atatctacta tcccctactt
    22621 gttcacatgt taagcaacag cctctcctta atcattttag ctatcagtat agtaaaatga
    22681 aataagaaca ggacaaatcg atttctaaca atgttttaga agtagaggtg tactattcta
    22741 gtttcaatat actgtaatat gtgatgaaaa tgccagtaat gataccgaga aaaaagctga
    22801 gaaacttttc ccagctttat ttgttatagt caaagagaat gacttgttcc tgtgcatcta
    22861 catgagcatg gaccccaaag ggtacaattg ctcttggagt tgcgtggccg acattcagat
    22921 tatagacaat cgggatattg ctgtcaatga tatccaatag tgcctcttta tagtcgtcat
    22981 ggaaagtttc atccataggt tttccgacca agagtccatt gatgaccgcg aatatgccag
    23041 tgtcctttaa agttagcaac atctttttga agtcttctgg cttaggcttt tcttcgcttg
    23101 tttcgagcaa gaggattttc ccttcccagt ctgacaagtc agggaaaagt ttgtattttt
    23161 ggcagagttc cgtgctatct gcgtatcgag agttgtcaaa gatatcgtag agggattcga
    23221 ggcaaccacc gaggattttc ccctcgaact gggcacttcc ttgcaacaag tcaaaacctg
    23281 tatttgtatg actgacacga ggtgttccca gggccgtggg actaaaatca gttcgttcct
    23341 cataccaaac gtcactaggg cggatttctg aaattcttcc cgtctcaatc aattctttaa
    23401 agtagtgaag gctataggct agcatttctt tgtctaattc acaaatgtct gctaaaaagg
    23461 attgaccata aaaagtcttg attcctaatt tatgcaacat gaggtggttc atggttgtat
    23521 ccgagaagcc aagaaaaatt ttttgtttga taaccttttg gagttggtca ttttcaaaaa
    23581 gataaggtag caagcgatag gtatcgtctc cactgatggc acataggatc atgtcgatgc
    23641 tatcatcaga aaaggcatga atcaaatcct ctgcacgagc ttcaggatgg tccttgataa
    23701 agtctaatcc ttttaacgaa tggggcaaaa agatgggatt gagtcccaga tccttgagac
    23761 gttggatacc caagtccact tcgtgtttga caaaatcctc tccgataatg ccactagata
    23821 aactaacaat accaatagta gaaaccatat ctcatcctcc tagaaataga ttgagcctat
    23881 tttatcacaa aatataagag aaagctatgt gggatttcag aagaatactt ttaatactct
    23941 tcgaaaatct cttcaaacca cgtcagtttt atttgcaacc tcaaagctgt gctttgagca
    24001 acctgcagct agcttcctag tttgctcttt gattttcatt gagtataact caaaaaagta
    24061 agtgaaaaag caaccgcacc tgcagttgct tttatcgttt tcttattctt gatagcgtgt
    24121 tggtcctgca cttgcactac ggatattcaa gcgtttcttg agatagaagc gaagggctag
    24181 gagggctact ccaataatag ctagtggcaa tggatccagt actgggttaa ggctagctgg
    24241 taggaagctt gttgcaaaga agacaagcaa ccaaaggaac atagaagtta ggataactag
    24301 tacagatttc cagaaaggtg gacgttgact gcgatccata tctggtccat agtattggta
    24361 aacaaagtag tacatcaagt agaaggcaaa tccaccaacc agtccaacta atagaagagt
    24421 aatcaatcca tagccgaaag cttgatctgc cgcaaagaag gttgtgaggg cgctgacaag
    24481 ggcaaagagg ctagtgatga aaagagctga gtccataatc atcagttttg gatcatcatt
    24541 ttcttttgga tgctcttttt cgtactgctc tttgacagtg aagctatgag cccaatgagt
    24601 tggtgcgccg tatagggaac gggcagttgt acctttagat tgctcctcaa ggatttgggg
    24661 aatgacttcc tcaaaaatag tctggatttc agcgtctgtt ttcccatctt tgatgaattg
    24721 ttgggtagca atgtggacaa actcttggtt tttcttagtt aatttttgta gatcaatttg
    24781 agacatagga actcctctta gaaccatttt ttatggatga gatagagagt gagcgagaca
    24841 ctcatagcaa aggcgataaa gacgattaac cagaaggcat ttggctctcc gtttagggga
    24901 atttcattat ccttaaagtt catcccgtag gcagaaaaga ccatggttgg gatggacatg
    24961 acgatggtca caagggccaa ggttttcatg atgttgttct ggttgttaga aatgatagag
    25021 gcaaaggtct ctgtcataga atgcaagacg tttccataaa tatctgccat ctcgatggcc
    25081 tgttgggttt caatcagggt gtcttcaagc aggtcttcgt cctcaaggta tttcttgata
    25141 ttgctggttg aactggtcaa tttcttaatc acgcgctcat ttgttttgag ggaggccttg
    25201 aaatagacga tagttttttc caattccatg agctcaatca attcttcatt acgagttgat
    25261 tgatgcagtt gactttcgat ttgttcactc ttgcggtcga ttgaacgaag ggctgttagg
    25321 taaagctctg cattgcgata aagaatttga aagataaaac gtgaacgcat gaaggtatag
    25381 aaattacgca atcgacggtt gataaagaca tcaaggacag gtagtggttc caaacacgta
    25441 gtgataatgg tttcctcagt gatgataata ccaagcggga tggttacgta gtaggtgcgg
    25501 ttatttcttt cctccgtgac cggcacgtct acgataatca gggtatactc gtcttcaatg
    25561 gtaatacgag acatttcttc cgcatcgagc ggtgctcgaa ggtcggcaat atcaatatcg
    25621 aaggtgttgg cgatttcgag tgattcattt tgagtcggat tgacgagatt gatccaagta
    25681 cccggttcaa gcgtatcgat ctctttaaat tcagttgttg tagagagaaa aacttgtttc
    25741 atatccctta tcctttctca tttttcagat tttttcacac tgtactatta tactacaaaa
    25801 tcggcctttt gggtaataga atctcacttt ttttggtata atggtaagca ataatggact
    25861 agaaagaaca aagatgcaag ataaaattgt cattcatggg gcgcgtgccc ataatttaaa
    25921 aaatattgat gtggagattc cgcgagacaa gttggttgtc gtgactggct tgtcaggttc
    25981 agggaagtcc agtctggctt ttgatactct ctatgcggag ggacaacgtc gctatgtaga
    26041 gagtttgtct gcctacgctc gtcagttctt gggaaatatg gaaaaaccag atgtagatgc
    26101 cattgatggt ctcagcccag ctatttccat cgaccagaaa acgactagta aaaatcctcg
    26161 ctcgacggtg ggaacgacga ctgaaatcaa tgactatctg cgtctcctct acgcacgtgt
    26221 ggggacgcct tactgtatca acggacatgg agctatcaat gcttcttctg tggagcaaat
    26281 cgttgataag gttttggagt tacctgaacg ccagcgcttg cagatcttgg ctcctgtcat
    26341 ccgcaagaaa aaaggccaac ataagagtgt tatcgagaag gttcagaaag acgggtatgt
    26401 tcgtgttcgt gtggatgggg aagtctatga tgtgaccgaa gtgccagagt tgtctaagag
    26461 caagcaacac aatatcgatg tcgtggttga ccgtattgtt atcaaggagg gcattcgtag
    26521 ccgtctcttt gattccattg aagctgccct tcgtatcgca gaaggttatg tgattatcga
    26581 caccatggac gactctgagt tgttgttctc tgagcattat gcctgtccag tttgtggatt
    26641 tactgtccca gagttagaac ctcgtctctt ctctttcaat gctccctttg gctcttgtag
    26701 tgagtgtgac ggcttgggga ttaagctgga ggtggatact gatttggtag tgccagatgc
    26761 cagcaaaacc ttacatgagg gagcgctggc accttggaat cctatctcat ccaactacta
    26821 tccaaacatg ttagagcagg ccatgaaagt ctttggagtg gctatggata agccttttga
    26881 ggacctgtca gaagaagata agaacttgat tctctacggc tcagatggta aggaattcca
    26941 tttccattat gaaaatgaat ttggtggtgt gcgcgatatc gacattccgt ttgagggagt
    27001 tatcaataat atcaaacgtc gttaccatga aaccaatagc gattacactc gcactcagat
    27061 gcgtctctac atgaatgagc tgacctgcgg aacctgtcaa ggctatcgtc tcaatgacca
    27121 ggccttgtct gtccgtgtgg gcggccagca agggccacat attggagaaa tctcagacct
    27181 gtctatcgct gaccacttgg acttggtgag ccagttaact ttgtctgaaa atgaagccat
    27241 cattgctcgt cccattctca aggaaatcaa ggatcgtttg accttcctta ataatgtggg
    27301 tcttaactat ctaaccctgt cacgttcagc aggaaccctt tcaggtgggg aaagtcagcg
    27361 cattcgtttg gcaacccaga ttggttccaa cctatcaggt gtcctctata tcctagacga
    27421 gccgtcaatc ggtcttcacc agagggacaa tgaccgcctg attgccagtc tgaaaaagat
    27481 gcgtgacttg ggcaatactc ttatcgtggt ggaacacgac gaagatacca tgcgtgaagc
    27541 tgattatctg attgacgttg gtcctggtgc cggtgttttt ggtggtgaga ttgttgcagc
    27601 aggtacacct aagcaagtgg ctcgcaacag caagtctatc acaggtcagt acttgtcagg
    27661 caaacgtgtc atcccagtac cagaagagcg ccgtgtcgga aatggtcgtt ttattgaagt
    27721 gacaggagcg cgtgagaaca acttgcaaaa tgtcacggct cgctttccac taggaaaatt
    27781 tatcgcagtg acaggtgtgt cgggttcagg gaaatcgact ctaatcaaca gcattctcaa
    27841 aaaagccatt gcccagaagc tcaaccgtaa ttcagacaaa cctggtaagt ttaagactat
    27901 tacagggatt gagcatgtcg accgtttgat tgatattgac cagagcccta tcggacggac
    27961 gccgaggtct aacccagcta cctatacagg agtttttgac gatatacgtg acctttttgc
    28021 tcagacaaat gaagccaaga ttcgaggcta caagaagggg cgcttcagtt tcaacgtcaa
    28081 gggaggtcgc tgtgaagctt gctcaggtga cgggattatc aagattgaga tgcacttctt
    28141 gccagatgtt tatgtggctt gtgaagtttg ccacggaacc cgctataaca gtgaaaccct
    28201 agaagttcac tacaaggaaa agaatatttc gcaggtcttg gatatgacgg tcaacgatgc
    28261 ggtagaattt ttccaacaca ttccgaaaat tcaacgcaaa ctccagacca tcaaggatgt
    28321 aggtctaggc tatgtgacct tgggacagcc agctaccacc ctttctgggg gagaagccca
    28381 acgtatgaag ttagctagcg aactccacaa acgctcgaca ggaaaatctt tctacattct
    28441 ggatgagccg acgacagggc ttcatacaga ggacattgct cgcctgctca aggttttagc
    28501 tcgctttgta gacgccggca atacagtcct cgtcatcgag cacaatctgg atgttatcaa
    28561 gacggcagac catatcattg acttgggacc tgagggcggt gtcggtggtg gaaccatcat
    28621 cgtaacagga actccagaag aagtagctgc caacgaagcc agctatacag gacactattt
    28681 gaaaggaaag ttacatcatg aataaacgcg tacaagcatt tctagctaaa atgcaagaaa
    28741 aagaactaga tggtatcatc atcaacaatc ttaaaaacgt ctattatttg actggttttt
    28801 ggggctcaaa cggaacagtc tttatcagcc gtgaccgtca ggtcttagtg acagactctc
    28861 gctatatcat cgcagctaag caagaaacca gtggttttga gattgtggct gatcgtgatg
    28921 aattggctgt cattgcagga attgttaagg acatgaactt gactcgtatc ggttttgaag
    28981 atgagatttc agtgtcttat taccaccgta tgcaggcagc ttttgcaggt ttgaacttgc
    29041 ttccacaaac tcagtttgtg gaaggtcttc gtatgattaa ggatgaggca gagattgcag
    29101 cgattcgcaa ggcttgttct atctcagacc aagctttccg cgatgcgctt gactttatca
    29161 aaccaggaaa aactgaaatt gagattgcca acttccttga tttccgcatg cgtgagttgg
    29221 gagcatctgg cttatctttt gatacgatcc tagctagcgg tatcaattct tctaaacccc
    29281 atgcccatcc aatgcacaaa ccagtggagt tgggagaagc cattaccatg gacttcggct
    29341 gtctctatga ccactatgtc agtgatatga cccggactat ctatctaggg catgttagcg
    29401 atgagcaggc agagatttac aatacggttc taaaagctaa ccaagccttg attgaccaag
    29461 ctaaggcagg cttaggtttc cgtgactttg acaaaatccc tcgtgatatt atcattgagg
    29521 caggttatgg tgactacttt actcacggca ttggccacgg tattggtctg gatatccatg
    29581 aggaacccta ctttagtcag acttctacag aaactattaa gacaggtatg gccttgaccg
    29641 atgaaccagg tatctatatc gaaggcaaat atggcgttcg tatcgaggat gatatcctga
    29701 ttacagagac aggttgtgaa ttattgaccc tagctccaaa agagttgata gtcatttagt
    29761 tgtttgtcaa gaaaaaagta cgaaaatgac gaaaaaagtc aaaaaaaatt aaaaataggt
    29821 cgcaagtcgg atgtttttta tggtataata gactaaactg atagtaacat gtagcgaaag
    29881 gggtaggtac atgattaaaa tttatacagt ctcaagttgt actagttgta aaaaagcaaa
    29941 aacctggctc aatgcccacc agttaagtta taaagaacaa aaccttggta aagaaggaat
    30001 tacgagagaa gaattactgg atattctaac caaaacagat aacggaatag ccagcatcgt
    30061 ttcgtctaaa aatcgctatg ccaaagccct tggagtggat attgaagatt tgagtgtcaa
    30121 tgaagttctc aatctgatta tggaaacacc gagaatttta aagagcccaa tccttgtaga
    30181 tgaaaaacgc ctgcaagttg gctacaagga agacgatatt cgtgccttcc taccacgctc
    30241 tgtccgtaat gtagaaaatg cagaagcacg tttgcgtgca gctctataaa catcaaggct
    30301 gggagcactt cccagtctta ttctatttta atttcaaaaa gaaagaagaa agaaatgaaa
    30361 aaaatagttc ttgttagtct agctttcctt tttgtcctgg ttggttgcgg acagaaaaaa
    30421 gaaactggac cagctacaaa aacagaaaaa gatacgcttc agtcggcatt gccagttatt
    30481 gaaaatgctg agaagaatac agttgtaact aagactttgg tcttgcccaa gtcagatgat
    30541 ggtagccagc agacacaaac aattacttac aaagacaaga cttttttgag tctagctatc
    30601 caacaaaaac gtccagtctc tgatgagttg aagacttata ttgaccaaca tggagtggag
    30661 gaaactcaaa aagctcttct tgaagcggag gagaaggata agtctatcat tgaagctcgt
    30721 aaattggcag gtttcaaact tgaaacaaaa ctattgagcg caacggaact tcaaacaacg
    30781 actagttttg attttcaagt tctggatgtc aagaaggctt cccagttgga acatctgaag
    30841 aatattggtt tggaaaatct tttgaaaaat gaaccaagca aatatatttc agatagattg
    30901 gcaaatggcg cgacagaaca atagaaaatc caaataaata gactgcctga attgtagaag
    30961 gtaaggaatt atgctataat ggtactattc taaggaaaga gggtgttaga atgggattta
    31021 ctgaagaaac agtacgtttt aaattggacg attccaataa aaaagaaatt agcgaaactt
    31081 tgacagatgt ttatgcttcg ttgaacgata agggttacaa cccaattaac caaatcgtag
    31141 gttacgtatt gagtggagac cctgcctacg ttcctcgtta taataatgca cgaaatcaaa
    31201 tccgtaagta tgagcgtgat gaaatcgttg aggaattggt tcgctactac ctcaaaggac
    31261 aaggagtcga tctataacct atgagaatta tgggattgga cgtcggttca aaaacggtag
    31321 gggtggcgat tagcgatccg cttggtttta cagctcaagg gcttgaaatc atccagataa
    31381 atgaagaaca aggccaattt ggttttgacc gcgttaagga attggttgat acttacaagg
    31441 tggaacgatt tgtagtgggc ttgcctaaaa acatgaacaa tacaagtgga ccgcgcgtag
    31501 aagctagtca agcctacgga gcaaagctag aagagttttt tggtttacca gtagactatc
    31561 aggatgaacg cttgacaaca gtggctgctg agcgcatgtt gattgaacaa gcagatatca
    31621 gtcgcaataa gcgcaagaaa gtcattgata agttagcagc tcagctgatt ttacaaaatt
    31681 atttagatag aaaattttaa tataaaggag aggctatgtc acacgatcat aaccacgacc
    31741 acgaagaacg tgaactaatc acactagtag atgagcaagg aaatgaaacc ttgtttgaaa
    31801 tccttttgac aattgatgga aaagaagaat ttggtaaaaa ctatgttctt ctagtaccag
    31861 ttaacgcaga agaagacgaa gacggacaag ttgaaatcca agcttactca ttcattgaaa
    31921 atgaagatgg aacagaaggc gaattgcaac caatcccaga agactcagaa gacgaatgga
    31981 acatgattga agaagtcttc aacagcttta tggaggagtg atacagtctg ggagactgta
    32041 tcagcccaac tccagaaatg gggaagagtt ggaacgtcca gtgaacattt ttactccaac
    32101 tcttagaaat tgagaagagt tggaacatct agtggatgtt tttagcccat attcacattc
    32161 atagtagcta gttattagct aaccaggtaa gaggtcggga cgaaaatcct ggccttgttt
    32221 ttattagtaa ccatacttta atgcgataat tgattggact tttgtcaagg agatgtgtat
    32281 gtttgaagta gaagaatggc tccatagtcg gattggtttg aattttcgat caggtttggg
    32341 ccgaatgcag caagcggtgg atttgttagg aaatcctgag cagtcttacc ctattatcca
    32401 cgtaacaggg actaatggga aaggatctac cattgctttt atgagggaat tatttatggg
    32461 gcatggcaaa aaagttgcga cctttacctc ccctcatatc gtctctatca atgaccgaat
    32521 ctgcattaat gggcaaccta tagcagacgc agactttatc cgtttgactg atcaggtcaa
    32581 ggagatggag aaaacgcttc tgcaaactcc tgcccagttg tccttttttg aattgctgac
    32641 cttagttgct tttctttatt ttagggagca agaggtggat ttggttttat tagaagtggg
    32701 aattggtggc ttacttgaca cgaccaatgt ggtaactgga gagcttgctg tcatcacctc
    32761 cattgggctt gaccatcaag aaaccttggg tgatagtcta gaagcaattg cagagcagaa
    32821 agctggtatt ttcaaggctg gtaaaaaggc agtgattgcg aaattgcctc cagaagctag
    32881 acttgtctgt cagaaaaaag ccgaatcttt agctgttgac ctttatcagg caggtcaaga
    32941 tttttcagtg ctgaatggtg atttttcaag ctctttacta aatctttcac agctgaacat
    33001 aggcttagaa ggagcctatc agcaggagaa tgcggccttg gcgttgcaaa cttttcttct
    33061 ttttatggga gaaagaaagg aagctattga tgaacaggct gtaagaaagg ccttggaaca
    33121 gacccattgg gctggtcgct tggagcgtat tcgcccacag atttacttgg atggtgctca
    33181 taacctccct gccttgactc gcttggttga gtttatcaaa gaaaaagagc aggaaggcta
    33241 tcgacctcaa atcctctttg gatccttgaa acgtaaggat tatcaaggga tgttgggtta
    33301 tctgactgaa aatttacctc aagtggaact caaaatgacc ggctttgact atcaagggtc
    33361 tttggacgag acagatgtaa caggttacca tgtaattccc tcttaccgag aatttatcag
    33421 cagtttcgaa gaaagggcag acgctcaaga cttgctgttc gttacagggt ctctctattt
    33481 tatctcagaa gtacggggct acctgctgga ccgtgagcag ataaattgac cccctttttt
    33541 gaacttgtta tactagggga attgctggtt agagaaaatt tctctaaatt ggtagcagaa
    33601 aggaaattca tcatgaaatt aaaaagattc acactttctc ttgcttctct agcaagtttt
    33661 agtctcttag tagcttgttc acaaagagct caacaggttc aacagcctgt tgctcagcag
    33721 gtccaacagc ctgctcaaca gaataccaat actgcaaatg caggaggtaa ccaaaatcaa
    33781 gcggctccag tacaaaacca acctgttgct caaccgaccg atattgatgg gacttatact
    33841 ggtcaggatg acggagaccg tatcacttta gtggtaactg gaacgactgg tacatggact
    33901 gagctcgaat ctgacgggga tcagaaagtc aaacaggtta catttgattc agcaaatcaa
    33961 cgcatgatta ttggcgatga tgtcaaaatt tacactgtaa acggtaatca aatcgtcgta
    34021 gatgatatgg atagagaccc atcggaccaa atcgttttaa ctaaataaga ctatgcaagt
    34081 agaaagggct ggatttttca gcctttttac ttttacctag aaaataatca taaatacttg
    34141 ccttctaccg aatacctgcg ttatactagt atcaattact tgtttttagc attcaaacta
    34201 tcaaggaggg gatatgaaat ataggaaatt tcaattattg atgtccaagt atggctttag
    34261 tctttcgatt atgctacttg aactttgtct tgtttttggt ctctttcttt atttaggacg
    34321 catggctccc attttatgga ttactgtcct cattctactg agtatcatca caatcatttc
    34381 gatagtcaac cgtaatacga ctcctgagaa taaggtaacc tggttgttag tagcctttgt
    34441 gccagtattt ggtcccttgc tctatctgat gtttggtgaa aggcgattgt ccaaaaaaga
    34501 aatcaaacaa ctgaagaagc taggctctat gcatttccaa gaagcaaata gccagctact
    34561 aaaagagaaa ttaaaagaaa gtgacaaggc agcttatgga gtcatcaagt ccttattgag
    34621 tatggatacc aatgctgaca tctatgatca aactgcctct acattttttc ctaacggaga
    34681 agctatgtgg aaaaagatgg tagaagatct taaaaaggct gagaaattta ttttcttgga
    34741 atattacatt atagaagaag gtttgatgtg gaatcgcata ctagatatac tagagcaaaa
    34801 ggtagctcag ggtgtagagg ttaagatgct ctatgatgat atcggctgta tggctacttt
    34861 aacaggagat tatgcacatc gacttcgtca gctgggcatc gaggcccata aattcaataa
    34921 agttattcct cgtttgacag tggcttataa taacagagat catagaaaaa tattgattgt
    34981 tgatggtcag atagcctata ctggtggggt caatctggca gatgagtaca ttaaccacgt
    35041 cgagagattt ggttattgga aggatagtgg aattcgctta gacggactag cagtaaaagc
    35101 cctgacacgc ttatttttga ccacttggta cattaatcga ggagaaatta gtgattttga
    35161 tcaatatcat ttagaaaatc attctatccc gagtgacggt ttaaccattc catacggaag
    35221 tggacccaag ccaatttttc gagcgcaggt agggaaaaaa gtttatcaga gtttaatcaa
    35281 tcaagcaaca gaatcggtct atattacgac accttatttg attatagatt atgatttaac
    35341 agagacaatc aaaaatgcag ctatgagagg ggtcgatgtt cgaattatca ccccttacat
    35401 accagataag aagttcattc agttagtcac gagaggagct tatcccgacc ttctttctgc
    35461 tggtgttcgg atttatgagt atagtccagg ttttattcat agtaagcaga tgttggtaga
    35521 cgaagatttt gcggtggtgg ggacaatcaa tctcgactac cggagcttgg tacaccatta
    35581 tgaaaatgca gtcttactct ataaaactcc ttctataagg gaaatcgccc gagattttcg
    35641 aaatatattt gcagattctc aggaagtcta tcctcattct atcaaaacga gctggtatca
    35701 aaagcttgta aaagaaatcg cccagctatt cgcccctatc ttataagaaa tctagaactt
    35761 aggatacaaa ccagacctat ttttcttgtc ttttactaat agaaagaaag aggaggggaa
    35821 ttcatgctaa ctaaggaaga agtgaatgat atgattgagt tcaaacagac acatttacac
    35881 cgctttcggg aaattgaaac ctttgtgaaa ctatgcaaaa aatcactcaa acagccatcg
    35941 caagctgaca atcctaggac tttttgatat actaagacag ataaattgaa caggagaaac
    36001 gatatgagtg tgtatggtag agtagaagaa gttcataagg agaatcgtga acctctagaa
    36061 taccaaatcg aacaagaatc gcatcatcgt gaatcaagtc gtcttccttt ggtgaaaatt
    36121 ttactatgga gtacgcttgt aacggggata actctaggag taccgctatt actcgactta
    36181 atgagtgcac aagaagtgca ggatttttat gcaggttggg ggcttcatca gacagggaag
    36241 atttacagcg actattatgg aagtcaaggt ttgctttatt atttgctgac ttacgtgagt
    36301 cagggcggat ttttctttgc catctttgag tggttagcct tggtagcagg aggatttttc
    36361 ctttttagat cagcggacac cttgacagag caaggagacc aagctggaca tctggtgact
    36421 attttttaca tgctagttac aggtcttgct tttggtggag gctatgcgac tcttttagcg
    36481 cttcctttct tattcgcagc ctttagttta gttgcggctt acctaagcaa tccaagccat
    36541 gataagggat ttgtacggat tgggctagct ttggcaggcg gatttttctt tgctccctta
    36601 tcatcgctcc tgtttattgc tgtagtgagt ttaggcttgt tggtctttaa ccttgggcat
    36661 agacgctttg cgcatgggtt ttatcagttt cttgcagtgg ctttaggttt ttcacttgtc
    36721 ttttatccaa ctgcctacta tagtgctgca acaggaagtt ttggggatgc gattagtggt
    36781 attcgttatc ctattgacag tattcgcttt gattttactt ctaaaatttt agagaatatg
    36841 tttttttatg gcttgttgtc ccttggtttg ggatttgtgg tttgtatctt tttaggtctc
    36901 tttcaatcca aaccctttaa actatacgtc atttcggttc ctgcaagtct tgtggtaatt
    36961 ttaggtttga ttttactttt cttttcacaa gagcctctgc acgcttctta tttgatggtc
    37021 gtcttccctg ttttcctact tttattggta accaatatta agagtcaaca gagggggcgt
    37081 agtgctagaa gaagccgaag agaaacgcca gttagcctat ggagtcgttt cttcaaagga
    37141 aatctatatc tgctagtttt tgggtttgtc tatcttttgt ctgttccttt tttgatgaag
    37201 tttgtccttt atccagtacc ttatcaagaa cgtaatcgtc ttgctgattt ggtaaaagag
    37261 gagacaaata cggaagatgc tatctatgca tgggatgata ctgcgactct ttatcgtaag
    37321 agtgagcgct tgtcgccatc ggcgattttg tccccgttgc actatacagc aactgaggaa
    37381 aatcgtaata agttacttaa tgacttgaaa gaaaaacaac ctaaggtgat tgtggtaaat
    37441 gacaaggtgg tagtctggtc tgaagtggaa acacttttaa aagaaaatta ccaacaagta
    37501 aagactgatt actcagagtt taaagtctat aaaattaaat aaccaaatca atatcttgtg
    37561 tatttttaaa aattttagga tttttaacac aagatattga tttttctttt tagagtggta
    37621 taatactttt tagaaagaac attttagaaa agagcatgcg tatgattgca ctagaagaaa
    37681 aaattacaat tttgccaact ctcttcgtcg agaaacgaga tgggagacgt gttgtatttg
    37741 atgtggacaa gattgacaag gctctccaca aggcggctga caaggttatg gatgtgacac
    37801 ccctggttga aaaacgcctc aatgatctga ctgagcgaat tattacagaa attcatagtc
    37861 gctttccaca gggaattaag atttacgaaa ttcaaaatat cgtagaacat gaactccttg
    37921 aagccaaaga atatgcgctg gctgaggagt atattactta tcggacacag agggattttg
    37981 agcgctcaaa agcgacggat atcaacttta gtattcataa acttctcaac aaagaccaga
    38041 cagttgtcaa tgaaaatgct aataaagaca gtgatgtctt taacactcag cgtgatttga
    38101 cagcagggat tgttgggaaa tcaatcggac tgcaaatgct tcctaagcac gtagccaatg
    38161 cccaccaaaa gggggatatc cactatcacg atttggacta cagtccctat acccctatga
    38221 ccaactgctg tttgattgat tttaagggta tgttggaaaa tggttttaag attggaaatg
    38281 cagaggtaga gagtcccaag tctatccaga ctgcgacagc acagatttct caaatcattg
    38341 ccaacgttgc ttctagccag tacggtggct gttcagctga ccgtatcgat gaaattttgg
    38401 cgccttatgc agagaagaat tatcaaaaac atctcaaaga tgcagaagag tgggtattgc
    38461 ctgaaaaacg ggaagattac gcttggaaga aaacgcaaaa ggacatctac gatgccatgc
    38521 aatctcttga gtatgaaatc aatactctct tcacttcaaa tggacaaaca ccttttactt
    38581 cgttaggttt tggtctggga accagtcgtt ttgaacgaga aattcaaaaa gctattttaa
    38641 acattcgcat caagggtctt ggttcagaac accgtacggc tatctttcct aaacttattt
    38701 tcactctgaa aagaggcctt aatttagagg aaggaactcc caactacgac atcaagcagt
    38761 tggctcttga gtgtgcaacc aaacggatgt atccagatgt tttatcttac gataagattg
    38821 ttgacttgac aggatccttc aaggtgccta tgggttgccg ttctttcctc caaggatgga
    38881 aggatgaaaa tggtgtagaa gtcaattcag gtcgcatgaa tctgggtgtt gtgacggtta
    38941 atctgcctcg tattgctctt gagtctgaag gtgatatgaa taagttctgg gaaatcttca
    39001 acgagcgaat gaatatcgca gaagatgctc ttgtttaccg tgtcgaacgc actaaagagg
    39061 cgacaccagc aaatgctcct attctttatc agtacggtgc ttttggccat cgtctaggta
    39121 aagaagaaag tgttgaccag ctctttaaga atcgtcgtgc taccgtttcg ctgggctata
    39181 tcggcttgta tgaagtagcg acagttttct ttggtaacag ctgggaaagt aatccagatg
    39241 ctaaggaatt cacgctagac atcattcacg atatgaaacg ccgtgtagaa gagtggtcag
    39301 accaatatgg ctaccatttc tctatctact caacaccatc cgaaagtctg acagaccgtt
    39361 tctgccgact agatatagac aagtttggct ctattcctga tatcacagac aaggaatact
    39421 acaccaactc tttccactac gatgttcgta aaaatccaac accgtttgaa aaattggact
    39481 ttgagaaagt ctatccagaa gcaggtgcgt caggtggttt catccattat tgtgagtatc
    39541 cagtccttca gcaaaatcca aaggccttgg aagctgtctg ggattatgct tatgaccgtg
    39601 taggctatct aggcaccaat actccgattg accgttgcta caagtgtgac tttgaagggg
    39661 attttgaacc aactgagaga gggtttgctt gtccaaactg tggcaatagc gaccctaaaa
    39721 cagtagatgt ggtgaagcga acttgtggct acctaggtaa tcctcaagca agaccgatgg
    39781 tcaacgggcg tcacaaggaa atcgctgcgc gtgtcaaaca tatgaatggt tcaacgatta
    39841 aaatagctgg gcatcaagta acaaattaga aagaaatgaa atgggaaaat atcaactaga
    39901 cgataagggg cgcgcacaag tgacccgtta tcacgagaaa cactctaaag gtggagctgg
    39961 taagaaagaa cgcttgctta gcttcagaga acaattttta aacaagaaca agaaaaaata
    40021 aaagtgagag ccagctctcg cttttctcat agtgggaggt aaggatggaa ttacgcagac
    40081 caagattagc ggataagaaa gctgttttag atatgatgac agagtttgaa aaatttcagt
    40141 cgcctcacga cggcggtttc tgggatacag agaactttgt gtatgaagac tggttagaaa
    40201 gcaatcagga acaggaaatg ggaattaatc tgcctgaagg atgggttcct gcaattcagt
    40261 tagtggcttt ttctgagaaa ggtcaagcag ttggatttct taatctccgg ttgcgcctca
    40321 gtaactttct actagaagaa ggtgggcaca ttggctactc catccgtcca tctgaaagag
    40381 gcaagggtta tgcaaaagag actctccgtc agggcttgca agttgctaag gaaaagaaca
    40441 tcaagaaagc tctggtgacc tgtagcgtga ataatcctgc tagcagagca gtcattctag
    40501 caaatggtgg aatatttgag gatgctcgca atggagtcga gcgttattgg atagaggtag
    40561 cgaatgaata atccaaaacc acaagaatgg aaaagcgagg aacttagtca aggtcgtatc
    40621 attgactaca aggcctttaa ctttgttgat ggcgaaggcg tgcgtaactc tctctatgta
    40681 gcaggctgta tgtttcactg cgagggatgt tataatgttg cgacttggtc ttttaatgct
    40741 ggcattccct atacagcaga attagaagag cagatcatgg cagaccttgc ccaaccctat
    40801 gttcaaggct tgactttgct gggaggggag ccttttctca atactggcat tctcttgcct
    40861 ctagttaaac gcatccgaaa ggaattgcca gacaaggaca tttggtcctg gacgggctac
    40921 acttgggaag aaatgatgtt ggaaactcca gataaactgg aactcttgtc actgattgac
    40981 attcttgtcg atggaagata tgatcgaact aagagaaatc ttatgctcca gtttcgaggt
    41041 tcgtccaacc aacgaattat cgatgtgcaa aaatcgctca aaagtgggca agtagtgatt
    41101 tgggacaagc tcaatgacgg aaaagaaagc tatgaacagg tgaagagaga atgaagaaaa
    41161 aagacttagt agaccaacta gtctcagaga tcgagacggg gaaagtcagg acactgggaa
    41221 tatacggtca tggagcttca ggtaaatcaa cctttgcaca ggaattgtac caagctttag
    41281 attctactac agtaaatttg ctagaaacag atccctatat cacctccgga cgctatttgg
    41341 tagtacccaa ggacgcgccg aatcaaaagg tgacagccag tctgccagtg gcgcatgaac
    41401 tggagagttt gcagagagat atccttgcct tgcaggcggg tatggatgtc ttgacaattg
    41461 aagaaccttg gaaggctagt gaggtcttgt ctggagccaa accaattttg attgtcgaag
    41521 ggatgtctgt tggctttcta cccaaggaac tctttgaaaa aaccatctgt ttctacacgg
    41581 atgaggagac cgaattaaag cgacgccttg ctagagatac gactgtgaga aatcgcgatg
    41641 catcctttat attggctagc catcagatga gacgggagca gtatctgcga tactataaag
    41701 aaactgagtc taaggcggat atcttagtgg accaatcaga agataaattt gatgtcaaga
    41761 ggacttaact tatgtataga agaaatatag aagaaaatcc ctaattttag aaagaaaaag
    41821 taggaaaaca gtttcatccc aaaaaaacga aaaaacagca acaaatccct tgcaatcgca
    41881 ggggctttgt gttattctat tatggtgctg taaattacag ccttagtttt gatgcaagag
    41941 gttgcgacac gctcggttgc attgccacgc aacaccgcgt cggttttctt gtggagctag
    42001 cctattatct taaatagacg aaaaggagaa aaagatggca aacaaaaaaa tccgtatccg
    42061 tttgaaagct tacgaacacc gtacgcttga cacagcggct gcaaaaatcg tagaatcagc
    42121 tactcgtaca ggtgcacaag ttgcgggtcc aatcccactt ccaactgaac gtagcctcta
    42181 cacaatcatt cgtgcgactc acaaatacaa agactctcgc gaacaatttg aaatgcgtac
    42241 acacaaacgt ttgatcgata tcgttaaccc aactcaaaaa acagttgatg ccttgatgaa
    42301 attggatctt ccaagtggtg taaacgtaga aatcaaactt taatctaaaa tataaaagag
    42361 cagaggctgg tgtttcaatc taattgaaca cgggctaaac tcggtgtgaa aaagataaac
    42421 ttcctcgcgt ctgctagaca ctgtgtcagt ttcctatttt cacgttgagt ttgacgccct
    42481 ttgtatctta gacttgagca taaaaaacgc tcgttaaaaa ctttttgaat aaaaatatag
    42541 aaaaggaact attttctcat gacaaaagga atcttaggga aaaaagtggg aatgactcaa
    42601 atcttcactg aagctggcga attgatccct gtaacagtta ttgaagcaac tccaaacgtt
    42661 gttcttcaag ttaaaactgt tgaaacagac ggatacaacg ctatccaagt tggtttcgat
    42721 gacaaacgcg aagtattgag caacaaacct gctaaaggac atgtagcgaa agctaacacg
    42781 gctcctaagc gcttcattcg tgaattcaaa aacgttgaag gcttggaagt tggtgctgaa
    42841 attacagttg aaacattcgc agctggagat gttgttgatg taactggtac ttctaaaggt
    42901 aaaggtttcc aaggtgttat caagcgccac ggacaatcac gtggaccgat ggctcacggt
    42961 tctcgttacc accgtcgtcc aggttctatg ggacctgttg cacctaaccg cgtattcaaa
    43021 ggtaaaaacc ttgcaggacg tatgggtggt gaccgcgtaa caattcaaaa tcttgaagtt
    43081 gtacaagttg ttccagaaaa gaacgttatc cttatcaaag gtaacgtacc aggtgctaag
    43141 aaatctctta tcactatcaa atcagcagtt aaagctggta aataataaag aaaggggaaa
    43201 tcagtcacaa tggcaaacgt aacattattt gaccaaactg gtaaagaagc tggccaagtt
    43261 gttcttaacg atgcagtatt tggtatcgaa ccaaatgaat cagttgtgtt tgatgtaatc
    43321 atcagccaac gcgcaagcct tcgtcaagga acacacgctg ttaaaaaccg ctctgcagta
    43381 tcaggtggtg gacgcaaacc gtggcgtcaa aaaggaactg gacgtgctcg tcaaggttct
    43441 atccgctcac cacaatggcg tggtggtggt gttgtcttcg gaccaactcc acgttcatac
    43501 ggctacaaac ttccacaaaa agttcgtcgc ctagctctta aatcagttta ctctgaaaaa
    43561 gttgctgaaa acaaattcgt agctgtagac gctctttcat ttacagctcc aaaaactgct
    43621 gaatttgcaa aagttcttgc agcattgagc atcgattcta aagttcttgt tatccttgaa
    43681 gaaggaaatg aattcgcagc tctttcagct cgtaaccttc caaacgtgaa agttgcaact
    43741 gctacaactg caagtgttct tgacatcgca aatagcgaca aacttcttgt cacacaagca
    43801 gctatctcta aaatcgagga ggttcttgca taatgaattt gtatgatgtt atcaaaaaac
    43861 ctgtcatcac tgaaagctca atggctcaac ttgaagcagg gaaatatgta tttgaagttg
    43921 acactcgtgc acacaaactt ttgatcaagc aagctgttga agctgctttc gaaggtgtta
    43981 aagttgccaa tgttaacaca atcaacgtaa aaccaaaagc taaacgtgtt ggacgttaca
    44041 ctggttttac taacaaaact aaaaaagcta tcatcacact tacagctgat tctaaagcaa
    44101 tcgagttgtt tgctgctgaa gctgaataat ctaaggagga aatatcgtgg gaattcgtgt
    44161 ttataaacca acaacaaacg gtcgccgtaa tatgacttct ttggatttcg ctgaaatcac
    44221 aacaagcact cctgaaaaat cattgcttgt tgcattgaag agcaaggctg gtcgtaacaa
    44281 caacggtcgt atcacagttc gtcaccaagg tggtggacac aaacgtttct accgtttggt
    44341 tgacttcaaa cgtaataaag acaacgttga agcagttgtt aaaacaatcg agtacgatcc
    44401 aaaccgttct gcaaacatcg ctcttgtaca ctacactgac ggtgtgaaag catacatcat
    44461 cgctccaaaa ggtcttgaag taggtcaacg tatcgtttca ggtccagaag cagatatcaa
    44521 agtcggaaac gctcttccac ttgctaacat cccagttggt actttgattc acaacatcga
    44581 gttgaaacca ggtcgtggtg gtgaattggt acgtgctgct ggtgcatctg ctcaagtatt
    44641 gggttctgaa ggtaaatacg ttcttgttcg tcttcaatca ggtgaagttc gtatgattct
    44701 tggaacttgc cgtgctacag ttggtgttgt cggaaacgaa caacatggac ttgtaaacct
    44761 tggtaaagca ggacgtagcc gttggaaagg tatccgccca acagttcgtg gttctgtaat
    44821 gaaccctaac gatcacccac acggtggtgg tgaaggtaaa gcaccagttg gtcgtaaagc
    44881 accatctact ccatggggca aacctgctct tggtcttaaa actcgtaaca agaaagcgaa
    44941 atctgacaaa cttatcgttc gtcgtcgcaa cgagaaataa tattaaacta gtcgcttaag
    45001 caactagtaa atccgccagc tcggtagcgc tccataggag tgcaagccgc tgtggtacaa
    45061 catttaaagg agaaaatata aaaatgggac gcagtcttaa aaaaggacct ttcgtcgatg
    45121 agcatttgat gaaaaaagtt gaagctcaag ctaacgacga aaagaaaaaa gttattaaaa
    45181 cttggtcacg tcgatcaacg atcttcccaa gtttcattgg ttacactatt gcagtttatg
    45241 acggacgtaa acacgtacct gtttacatcc aagaagacat ggtaggccac aaacttggtg
    45301 aatttgcacc aactcgtact tacaaaggtc acgctgcaga cgacaagaaa acacgtagaa
    45361 aataaggaga acataaatgg cagaaattac ttcagctaaa gcaatggctc gtacagtacg
    45421 tgtttcacct cgtaaatcac gtcttgttct tgataacatc cgtggtaaaa gcgtagccga
    45481 tgcaatcgca atcttgacat tcactccaaa caaagctgct gaaatcatct tgaaagtttt
    45541 gaactcagct gtagctaacg ctgaaaacaa ctttggtttg gataaagcta acttggtagt
    45601 atctgaagca ttcgcaaacg aaggaccaac tatgaaacgt ttccgtccac gtgcgaaagg
    45661 ttcagcttca ccaatcaaca aacgtacagc tcacatcact gtagctgttg cagaaaaata
    45721 aggaggtaaa atcgtgggtc aaaaagtaca tccaattggt atgcgtgtcg gcatcatccg
    45781 tgattgggat gccaaatggt atgctgaaaa agaatacgcg gattaccttc atgaagatct
    45841 tgcaatccgt aaattcgttc aaaaagaact tgctgacgca gcagtttcaa ctattgaaat
    45901 cgaacgcgca gtaaacaaag ttaacgtttc acttcacact gctaaaccag gtatggttat
    45961 cggtaaaggt ggtgctaacg ttgatgcact ccgtgcaaaa cttaacaaat tgactggaaa
    46021 acaagtacac atcaacatca tcgaaatcaa acaacctgat ttggatgctc accttgtagg
    46081 tgaaggaatt gctcgtcaat tggagcaacg tgttgctttc cgtcgtgcac aaaaacaagc
    46141 aatccaacgt gcaatgcgtg ctggagctaa aggaatcaaa actcaagtat caggtcgttt
    46201 gaacggtgca gatatcgccc gtgctgaagg atactctgaa ggaactgttc cgcttcacac
    46261 acttcgtgca gatatcgatt acgcttggga agaagcagat actacatacg gtaaacttgg
    46321 tgttaaagta tggatctacc gtggtgaagt tcttccagct cgtaaaaaca ctaaaggagg
    46381 taaataacca atgttagtac ctaaacgtgt taaacaccgt cgtgagttcc gtggaaaaat
    46441 gcgcggtgaa gcaaaaggtg gaaaagaagt agcattcggt gaatacggtc ttcaagctac
    46501 aactagccac tggatcacta accgccaaat cgaagctgct cgtatcgcca tgactcgtta
    46561 catgaaacgt ggtggtaaag tttggattaa aatcttccca cacaaatcat acactgctaa
    46621 agctatcggt gtgcgtatgg gatctggtaa aggggcacct gaaggttggg tagcaccagt
    46681 taaacgtggt aaagtgatgt tcgaaatcgc tggtgtatct gaagagattg cacgtgaagc
    46741 gcttcgactt gctagccaca aattgccagt taaatgtaaa ttcgtaaaac gtgaagcaga
    46801 ataaggagaa ggcatgaaac ttaatgaagt aaaagaattt gttaaagaac ttcgtggtct
    46861 ttctcaagaa gaactcgcga agcgcgaaaa cgaattgaaa aaagaattgt ttgaacttcg
    46921 tttccaagct gctactggtc aattggaaca aacagctcgc ttgaaagaag ttaaaaaaca
    46981 aatcgctcgt atcaaaacag ttcaatctga agcgaaataa tagactaggg aaggagaaat
    47041 ttcaatggaa cgcaataatc gtaaagttct tgttggacgt gttgtatctg acaaaatgga
    47101 caagacaatc acagttgtag ttgaaacaaa acgtaaccac ccagtctatg gtaaacgtat
    47161 taactactct aaaaaataca aagctcatga tgaaaacaat gttgccaaag aaggcgatat
    47221 cgtacgtatc atggaaactc gcccgctttc agctacaaaa cgtttccgtc ttgtagaagt
    47281 tgttgaagaa gcggtcatca tctaatcaaa cctgaaagga gaaaactgaa atgattcaaa
    47341 cagaaactcg tttgaaagtc gcagacaaca gcggtgctcg cgaaatcttg actatcaaag
    47401 ttcttggtgg ttcaggacgt aaatttgcaa acatcggtga tgttatcgtg gcatctgtaa
    47461 aacaagctac tcctggtggt gcggttaaaa aaggtgacgt tgttaaagca gttatcgttc
    47521 gtactaaatc aggtgctcgt cgtgctgatg gttcatacat caaatttgac gaaaacgcag
    47581 cagttatcat ccgtgaagac aaaactcctc gcggaacacg tatctttggc ccagttgcac
    47641 gtgaattgcg tgaaggtggc ttcatgaaga tcgtgtcact tgctccagaa gtactttaat
    47701 ttttaggaac aaactagtcc cctagcttca agctagggtg cccttatggg cgtaagaaaa
    47761 atcaaggaga aacctaatgt ttgtaaaaaa aggcgacaaa gttcgcgtaa tcgctggtaa
    47821 agataaggga acagaagctg ttgtccttac tgcccttcca aaagtaaaca aagttatcgt
    47881 tgaaggtgtt aacattgtta agaaacacca acgtccaact aacgagcttc ctcaaggtgg
    47941 tatcatcgag aaagaagcag ctatccacgt atcaaacgtt caagttttgg acaaaaatgg
    48001 tgtagctggt cgtgttggtt acaaatttgt agacggtaaa aaagttcgct acaacaaaaa
    48061 atcaggcgaa gtgcttgatt aatcacgaag gaaaggagaa gtataatggc aaatcgttta
    48121 aaagaaaaat atcttaatga agtagttcct gctttgacag aacaattcaa ctactcatca
    48181 gtgatggctg tgcctaaagt agataagatt gttttgaaca tgggtgttgg tgaagctgta
    48241 tcaaacgcta aaagccttga aaaagctgct gaagaattgg cacttatctc aggtcaaaaa
    48301 ccacttatca ctaaagctaa aaaatcaatc gccggcttcc gtcttcgtga aggtgttgcg
    48361 atcggtgcaa aagttaccct tcgtggtgaa cgtatgtacg aattcttgga taaattggta
    48421 tcagtttcac ttccacgtgt acgtgacttt cacggtgttc caacaaaatc atttgatgga
    48481 cgcgggaact acacacttgg tgtgaaagaa caattaatct tcccagaaat caacttcgat
    48541 gacgttgaca aaactcgtgg tcttgacatc gttatcgtaa caactgctaa cactgacgaa
    48601 gagtcacgtg cattgcttac aggccttgga atgccttttg caaaataata taggaggtaa
    48661 atctaatggc taaaaaatca atggtagcta gagaggctaa acgccaaaaa attgttgacc
    48721 gttatgctga aaaacgtgct gcattaaagg cggcagggga ctacgaaggt ttatctaaat
    48781 tacctcgcaa cgcctcaccg actcgtttac ataatcgttg tagagttacg gggcgcccac
    48841 attcagttta ccgcaaattt ggtctgagtc gtatcgcttt tcgcgaactt gcgcataaag
    48901 gtcaaattcc tggtgtaaca aaagcatctt ggtaatttaa gatatcaagg gtgtcaaaac
    48961 tccaagtaaa aataggaaac ttgacgaaga aactaaagtt tctaggaaag tttatctttt
    49021 tcacacagag tttagcccgg gttcaattgg gcttgccaat ttgaacccga gctacagctt
    49081 tggcaaaaaa gaccaatttg ctttggagca ttgcttctgc attaaattgt ctatttttgc
    49141 tcgtgctgtt acgctctttg tatcatgtat taactagcaa gtgcaacttg caaactacta
    49201 gtaagaggag aaaaacaaaa tggttatgac tgacccaatc gcagacttcc taactcgtat
    49261 tcgtaatgct aaccaagcta aacacgaagt acttgaagta cctgcatcaa acatcaaaaa
    49321 agggattgct gaaatcctta aacgcgaagg ttttgtaaaa aacgttgaaa tcatcgaaga
    49381 tgacaaacaa ggcgtcatcc gtgtatttct taaatacgga ccaaatggtg aaaaagttat
    49441 cactaacttg aaacgtgttt ctaaaccagg acttcgtgtc tacaaaaaac gtgaagacct
    49501 tccaaaagtt cttaacggac ttggaattgc catcctttca acttctgaag gtttgcttac
    49561 tgataaagaa gcacgccaaa agaatgttgg tggtgaggtt atcgcttacg tttggtaaaa
    49621 tcaagataca aagctcgtaa agaacaaagc aaaattagga agttggagaa gtttgtttac
    49681 aaacaagcca acttatctat tttgcacagt tcttagagcg tgttcagttc agctcttgaa
    49741 ctaaataagt atctgaaccc cgtgaaaact ggccgttctg gcctgacaat ttaacaggag
    49801 aaaataaaca tgtcacgtat tggtaataaa gttatcgtgt tgcctgctgg tgttgaactc
    49861 gctaacaatg acaacgttgt aactgtaaaa ggacctaaag gagaacttac tcgtgagttc
    49921 tcaaaagata ttgaaatccg tgtggaaggt actgaaataa ctcttcaccg tccaaacgat
    49981 tcaaaagaaa tgaaaactat ccacggaact actcgtgccc ttttgaacaa catggttgtt
    50041 ggtgtatcag aaggattcaa gaaagaactt gaaatgcgtg gggttggtta ccgtgcacag
    50101 cttcaaggat ctaaacttgt tttggctgtt ggtaaatctc atccagacga agttgaagct
    50161 ccagaaggaa ttacttttga acttccaaac ccaacaacaa tcgttgttag cggaatttca
    50221 aaagaagtag ttggtcaaac agctgcttac gtacgtagcc ttcgttcacc agaaccatat
    50281 aaaggtaaag gtatccgtta cgttggtgaa ttcgttcgcc gtaaagaagg taaaacaggt
    50341 aaataatgtt gagtggttga tcatcaacca ccaacctatt ttccaacttt gtgcatagca
    50401 cacgatttaa aactaaagag gtgaaaactg tgatttcaaa accagataaa aacaaactcc
    50461 gccaaaaacg ccaccgtcgc gttcgcggaa aactctctgg aactgctgat cgcccacgtt
    50521 tgaacgtatt ccgttctaat acaggcatct acgctcaagt gattgatgac gtagcgggtg
    50581 taacgctcgc aagtgcttca actcttgata aagaagtttc aaaaggaact aaaactgaac
    50641 aagccgttgc tgtcggtaaa ctcgttgcag aacgtgcaaa cgctaaaggt atttcagaag
    50701 tggtgttcga ccgcggtgga tatctatatc acggacgtgt gaaagctttg gctgatgcag
    50761 ctcgtgaaaa cggattgaaa ttctaatagg aggacactag aaaatggcat ttaaagacaa
    50821 tgcagttgaa ttagaagaac gcgtagttgc tgtcaaccgt gttacaaaag ttgttaaagg
    50881 tggacgtcgt cttcgtttcg cagctcttgt tgttgttggt gaccacaatg gtcgcgtagg
    50941 atttggtact ggtaaagctc aagaagttcc agaagcaatc cgtaaagcag tagatgatgc
    51001 taagaaaaac ttgatcgaag ttcctatggt tggaacaaca atcccacacg aagttctttc
    51061 agaattcggt ggagctaaag tattgttgaa acctgctgta gaaggttctg gagttgccgc
    51121 tggtggtgca gttcgtgccg ttgtggaatt ggcaggtgtg gcagatatta catctaaatc
    51181 acttggttct aacactccaa tcaacattgt tcgtgcaact gttgaaggtt tgaaacaatt
    51241 gaaacgcgct gaagaaattg ctgcccttcg tggtatttca gtttctgatt tggcataaga
    51301 aaggggataa aatggctcaa attaaaatta ctttgactaa gtctccaatc ggacgcattc
    51361 catcacaacg taaaactgtt gtagcacttg gacttggcaa attgaacagc tctgttatta
    51421 aagaagataa cgctgctatc cgtggtatga ttacagcagt atctcactta gtaacagttg
    51481 aagaagtaaa ctaatgaagt tttaggggat gtgcactgta ccatccccta aaactagata
    51541 tagtcatcta tgatgacatc gtataggcga gttgatgggg gagacaacct tttctccctt
    51601 atcggcgcta gcattttaca aaagaggaga aaataaaaat gaaacttcat gaattgaaac
    51661 ctgcagaagg ttctcgtaaa gtacgtaacc gcgttggtcg tggtacttca tcaggtaacg
    51721 gtaaaacatc tggtcgtggt caaaaaggtc aaaaagctcg tagcggtggc ggagttcgcc
    51781 ttggttttga aggtggacaa actccattgt tccgtcgtct tccaaaacgt ggattcacta
    51841 acatcaacgc taaagaatac gcaattgtga accttgacca attgaacgtc tttgaagatg
    51901 gtgctgaagt aactccagtt gttcttatcg aagcaggaat tgttaaagct gaaaagtcag
    51961 gtattaaaat tcttggtaac ggtgagttga ctaagaaatt gactgtgaaa gcagctaaat
    52021 tctctaaatc agctgaagaa gctatcactg ctaaaggtgg ttcagtagaa gtcatctaag
    52081 agaggtgacc tatgtttttt aaattattaa gagaagctct taaagtcaag caggttcgat
    52141 caaaaatttt atttacaatt tttatcgttt tggtctttcg tatcggaact agcattacag
    52201 ttcctggtgt gaatgccaat agcttgaatg ctttaagtgg attatccttc ttaaacatgt
    52261 tgagcttggt gtcggggaat gccctaaaaa acttttcgat ttttgcccta ggagttagtc
    52321 cctatatcac cgcttctatt gttgtccaac tcttgcaaat ggatatttta cccaagtttg
    52381 tagagtgggg taaacaaggg gaagtaggtc gaagaaaatt gaatcaagct actcgttata
    52441 ttgctctagt tctcgctttt gtgcaatcta tcgggattac agctggtttt aataccttgg
    52501 ctggagctca attgattaaa actgctttaa ctccacaagt ttttctgacg attggtatca
    52561 tcttaacagc tggtagtatg attgtcactt ggttgggtga gcaaattaca gataagggat
    52621 acggaaacgg tgtttccatg attatctttg ccgggattgt ttcctcaatt ccagagatga
    52681 ttcagggcat ctatgtggac tactttgtga acgtcccaag tagccgtatc acttcatcta
    52741 tcattttcgt aatcattttg attattactg tattgttgat tatttacttt acaacttatg
    52801 ttcaacaagc agaatacaaa attccaatcc aatatactaa ggttgcacaa ggtgctccat
    52861 ctagctctta ccttccgtta aaggtaaacc ctgctggagt tatccctgtt atctttgcca
    52921 gttcgattac tgcagcgcct gcggctattc ttcagttttt gagtgccaca ggtcatgatt
    52981 gggcttgggt aagggtagca caagagatgt tggcaactac ttctccaact ggtattgcca
    53041 tgtatgcttt gttgattatt ctctttacat tcttctatac gtttgtacag attaatcctg
    53101 aaaaagcagc agagagccta caaaagagtg gtgcctatat ccatggagtt cgtcctggta
    53161 aaggtacaga agaatatatg tctaaacttc ttcgtcgtct tgcaactgtt ggttccctct
    53221 tccttggtgt gatttccatt ttaccgattg cagctaaaga tgtatttggt ctttctgatg
    53281 ttgttgcctt tggtggaaca agtctcttga tcattatctc tacaggtatc gaaggaatca
    53341 agcaattgga aggttaccta ttgaaacgta agtatgttgg tttcatggac agaacagaat
    53401 aaaagtattt actgaatcag taaatactga gggagtggag gtttaaactc tgacatttgt
    53461 aagagttgga tctcccctct tctattttgt ttttaaatcg gggtgaaaag actttttgct
    53521 tctatttaaa aataaaataa ggagatcaaa tcatgaatct tttgattatg ggcttacctg
    53581 gtgcaggtaa gggaactcaa gcagcaaaaa tcgtagaaca attccatgtt gcacatatct
    53641 caacaggtga tatgttccgc gctgcaatgg caaatcaaac tgaaatgggt gttcttgcta
    53701 agtcatatat tgacaagggt gaattggttc ctgacgaagt tacaaatgga atcgtaaaag
    53761 aacgcctttc acaagatgat attaaagaaa caggattctt attggatggt tacccacgta
    53821 caattgaaca agctcatgcc ttggacaaaa cattggctga acttggcatt gaactagaag
    53881 gtattatcaa tattgaagtg aaccctgaca gcctcttgga acgtttgagt ggccgtatca
    53941 tccaccgcgt aactggagaa actttccaca aggtctttaa cccaccagtt gactataaag
    54001 aagaagatta ctaccaacgt gaagatgata agcctgagac agtaaaacgt cgtttggatg
    54061 ttaatattgc tcaaggagaa ccaatcattg ctcactaccg tgccaaaggt ttggttcatg
    54121 acatcgaagg taatcaagat atcaatgatg tcttctcaga tattgaaaaa gtattgacaa
    54181 atttgaaata aagcgttttt cacacttgca aaaatccgct acaaatgtta tactgaaata
    54241 gtctgactta taattgttgt ctctgtgtct agaggcatcg aatcgaaatt tatggaggtg
    54301 cttttgcgtg gcaaaagacg atgtgattga agttgaaggc aaagtagttg atacaatgcc
    54361 gaatgcaatg tttacggttg aacttgaaaa tggacatcag attttagcaa cagtttctgg
    54421 taaaattcgt aaaaactata ttcgtatttt agcgggagat cgtgttactg tcgaaatgag
    54481 tccatatgac ttgacacgtg gacgtatcac ttaccgcttt aaataatcga aaaacttgga
    54541 gggataagaa atgaaagtaa gaccatcggt caaaccaatt tgcgaatact gtaaagttat
    54601 tcgtcgtaat ggtcgtgtta tggtaatttg cccagcaaat ccaaaacaca aacaacgtca
    54661 aggataagat agaaaggaga aaacatggct cgtattgctg gagttgatat tccaaatgac
    54721 aaacgcgtag taatctcatt gacttatgtt tatggtatcg gacttgcaac atctaagaaa
    54781 attttggctg ctgctggaat ctcagaagat gttcgtgtac gtgatcttac atcagatcaa
    54841 gaagatgcta tccgtcgtga agtggatgca atcaaagttg aaggtgacct tcgtcgtgaa
    54901 gtaaacttga acatcaaacg tttgatggaa atcggttcat accgtggtat ccgtcaccgt
    54961 cgtggacttc ctgtccgtgg acaaaatact aaaaacaacg ctcgcactcg taaaggtaaa
    55021 gctgttgcga ttgctggtaa gaaaaaataa tataggaggt aaaagtcttg gctaaaccaa
    55081 cacgtaaacg tcgtgtgaaa aagaatatcg aatctggtat tgctcatatt cacgctacat
    55141 ttaataacac tattgttatg attactgatg tgcatggtaa tgcaattgct tggtcatcag
    55201 ctggtgctct tggtttcaaa ggttctcgta aatctacacc attcgctgct caaatggctt
    55261 ctgaagctgc tgctaaatct gcacaagaac acggtcttaa atcagttgaa gttactgtaa
    55321 aaggtccagg ttctggtcgt gagtcagcta ttcgtgcgct tgctgccgct ggtcttgaag
    55381 taacagcaat tcgtgatgtg actccagtgc cacacaatgg tgctcgtcct ccaaaacgtc
    55441 gccgtgtata atcatcgcat tacactgctt ttcgtttaag agggagtaac taaatgatcg
    55501 agtttgaaaa accaaatata acaaaaattg atgaaaataa agattatggc aagtttgtaa
    55561 tcgaaccact tgaacgtggc tacggtacaa ctcttggtaa ctctcttcgt cgtgtacttc
    55621 tagcttctct accaggagca gctgtgacat ctatcaacat tgatggtgtg ttacatgagt
    55681 ttgacacagt tccaggtgtt cgtgaagacg ttatgcaaat cattctgaac attaaaggaa
    55741 ttgcagtgaa atcgtacgtt gaagacgaaa aaatcatcga actggatgtt gaaggtcctg
    55801 ctgaagtaac agctggtgac attttgacag atagcgatat tgaaattgta aatccagatc
    55861 attatctctt tacaattggt gaaggttctt ctctaaaagc gactatgact gttaacagtg
    55921 gtcgtggata tgtacctgct gatgaaaata aaaaggataa tgcaccagtt ggaacacttg
    55981 ctgtagattc tatttataca ccagttacaa aagtcaacta tcaagtggaa cctgctcgtg
    56041 taggtagcaa tgatggtttc gacaaattaa cccttgaaat cttgacaaat ggaacaatta
    56101 ttccagaaga tgctttaggg ctttcagcac gtattttgac agaacatctt gatttgttta
    56161 caaatcttac tgagattgct aagtcaactg aagtgatgaa agaagctgat actgaatctg
    56221 acgaccgtat tttagatcgt acgattgagg aactggactt gtctgtgcgt tcatacaact
    56281 gtttaaaacg tgccggtatc aatactgtgc atgatttgac agaaaaatct gaagcagaga
    56341 tgatgaaagt acgaaatctt ggacgcaaga gtttggaaga agtgaaactc aaactcattg
    56401 atttgggtct tggattaaaa gataaataaa ggaggaatac atggcttacc gtaaactagg
    56461 acgcactagc tcacaacgta aagcaatgct tcgcgatttg acaactgact ttttgatcaa
    56521 cgaatcaatc gtgacaactg aagctcgtgc taaagaaatc cgtaaaactg ttgaaaaaat
    56581 gattactcta ggtaaacgtg gtgatttgca tgcacgtcgt caagcagctg ctttcgtacg
    56641 taatgaaatc gcatctgaaa actatgatga agcaactgat aagtacactt ctactacagc
    56701 acttcaaaaa ttgttctcag aaatcgcacc tcgttatgct gaacgtaacg gtggatacac
    56761 tcgtatcctt aaaactgaac cacgtcgtgg tgatgcagcg ccaatggcga tcatcgaatt
    56821 agtataaaat catcaatttt gttgagtgtt atgatgatgg agtcttgtgc tcttagtcta
    56881 gctctggtct accgctagga tttcggtcct agcgggaaca ctcatcataa gttgggatag
    56941 tagacgcttg tttacgaaat tgtttttttc ttaagaacaa cttcgtaagc aggcgttttt
    57001 gagtattttc gttagaatta tgctatacta tttgaaaaga atcctgttta atgttaaggt
    57061 ttcttatttt aagaagaatt ggagtttact tatgaaagcg attataactg ttgttggtaa
    57121 agataaatct ggaattgttg caggtgtttc tggtaaaatt gcagaattag gattgaatat
    57181 tgacgatatc tctcaaactg tattggatga atattttacg atgatggctg ttgtatctag
    57241 tgatgaaaag caagatttta cctatcttcg taatgaattt gaagcttttg ggcaaacttt
    57301 gaatgtaaaa atcaatattc agagtgcagc gattttcgaa gctatgtata atatctagga
    57361 ggtcatcatg gatattagac aagttactga aaccatcgcc atgattgagg agcaaaactt
    57421 cgatattaga accattacca tggggatttc tcttttggac tgtatcgatc caaatatcaa
    57481 tcgtgctgcg gagaaaatct atcaaaaaat tacgacaaag gcggctaatt tagtagctgt
    57541 tggtgatgaa attgcggctg agttgggaat tcctatcgtt aataagcgtg tatcggtgac
    57601 acctatttct ctgattgggg cagcgacaga tgcgacggac tacgtggttc tggcaaaagc
    57661 gcttgataag gctgcgaaag agattggtgt ggactttatt ggtggttttt ctgccttagt
    57721 acaaaaaggt tatcaaaagg gagatgagat tctcatcaat tccattcctc gtgctttggc
    57781 tgagacggat aaggtctgct cgtcagtcaa tatcggctca accaagtctg gtattaatat
    57841 gacggctgtg gcagatatgg gacgaattat caaggaaaca gcaaatcttt cagatatggg
    57901 agtggccaag ttggttgtat tcgctaatgc tgttgaggac aatccattta tggcgggtgc
    57961 ctttcatggt gttggggaag cagatgttat catcaatgtc ggagtttctg gtcctggtgt
    58021 tgtgaaacgt gctttggaaa aagttcgtgg acagagcttt gatgtagtag ccgaaacagt
    58081 taagaaaact gcctttaaaa tcactcgtat cggtcaattg gttggtcaaa tggccagtga
    58141 gagactgggt gtggagtttg gtattgtgga cttgagtttg gcaccaaccc ctgcggttgg
    58201 agactctgtg gcacgtgtcc ttgaggaaat ggggctagaa acagttggca cgcatggaac
    58261 gacagctgcc ttggccctct tgaacgacca agttaaaaag ggtggagtga tggcctgtaa
    58321 ccaggtcggt ggtctatctg gtgcctttat ccctgtttct gaggatgaag gaatgattgc
    58381 tgcagtgcaa aatggctctc ttaatttaga aaaactagaa gctatgacgg ctatctgttc
    58441 tgttggattg gatatgattg ccatcccaga agatacgcct gctgaaacta ttgcggctat
    58501 gattgcggat gaagcagcaa tcggtgttat caacatgaaa acaacagctg ttcgtatcat
    58561 tcccaaagga agagaaggcg atatgattga gtttggtggt ctattaggaa ctgcacccgt
    58621 tatgaaggtt aatggggctt cgtctgtcga cttcatctct cgcggtggac aaatcccagc
    58681 accaattcat agttttaaaa attaagaaaa taggagaaat tttaagttct atttaagatt
    58741 agatgtgtat actataatca ttaaataaag acctcctaat attatttgaa acagataaca
    58801 ctgaattagt ttgaatttga ttttcatcta atatctttat ttaatgaact cctaaacttt
    58861 ttcataataa tctccttcaa aagtcgcctg tatgggtggc ttttatttta tcattcatga
    58921 tataatagaa gcaaacggag gacggaaaat ggtaaaagta cgattgtatt tggtacgtca
    58981 tggcaagacc atgtttaaca cgattggtcg cgcgcaaggt tggagcgata ctcccttaac
    59041 tgctgaaggt gaacgaggga ttcaagagtt aggaatcggt ttgcgagaat ctgatctaca
    59101 gtttgagcgc gcttattcga gtgattctgg tcgtaccatt cagaccatgg gaattatact
    59161 tgaagaactt ggcttgcagg ggaaaatccc ttatcgcatg gacaagcgta tcagagaatg
    59221 gtgtttcggt agttttgatg gagcctatga tggcgatctt ttcatgggca ttattcctcg
    59281 tatctttaat gtggaccacg ttcaccaatt gtcttatgct gaactggctg agggcttggt
    59341 agaggtcgat acagctggtt gggctgaagg ttgggaaaaa ctcagtggcc gaatcaagga
    59401 aggctttgaa ataattgcaa aagaaatgga agatcaaggt ggaggtaacg cccttgttgt
    59461 cagccatgga atgactattg gaaccattgt ttatctgatt aatggcatgc atccgcatgg
    59521 tctagataat ggtagcgtga cgattcttga atatgaggac ggtcagttta gggttgaagt
    59581 tgtcggtgac cgtagttacc gagagctagg acgtgagaag atggaagaag gttctattta
    59641 atcagtctag acttgcttgc catgagctag ggatttgata agaatatcaa gataagaaaa
    59701 aacagccgag ggtactcctt tcggctgttt ttgatgtgga aaactaaagt gtaatgctat
    59761 tgcttttaga gattttcata aacaagagca aggaacctac tgttagaaca gtcaggatag
    59821 ttgacaaggc tgcagctaca ccgtaatttc ctctgagaac ctctgtataa atagctacag
    59881 tcattgttct tgttttgaca ttgtagagga ggatagaagt agagagttct gaaatcagtg
    59941 tgacccaaga taggatggct ccagaaataa tatccgatag catcattgga gttgtaatct
    60001 tagcaaagat attgagacga ctacttccta agctttcagc agcttcttca atacttggtg
    60061 ctatttgttg taagctagca acagatgagc gaatagtata aggtaatttt ctggcagata
    60121 gagacataat caagatgaaa gcagtccctg taatcataag aaatccactt ccaaatagac
    60181 cagagaaatg aaggcaatcc ctagaacggt tcctggtaca atataaggta ccatactgag
    60241 gctgtcaatt aagtttgtaa acaaattccg ttttctaacg gctaggtagg agataaatgt
    60301 cgtaaataga acaactagaa ctaaggcaat caaagggata cgaatggtat tgaaaatagc
    60361 agatcccata cgattgaaag ctagcttgta actgtttgga gaataacctt taacaaatac
    60421 catacctgat gtttttagga aagaggtata aattaagtag atttgaggta aaacagagat
    60481 aaagataatt ccgtagactg ttgcataaat ggcagccatt tttccttttg tagttttttt
    60541 aggctcaatt ggatggagca gattcatgct gaaactgtag cggtttgcaa tgtgtttttg
    60601 gataaggaaa attgccaagg caatgataat cgccataatt gcaaaagcag aatttcctcc
    60661 aacctcgcta ataaattggg tataaatcag gacagggaaa gtccgatacc cttcgccaat
    60721 caacataggc gttccaaagt ctgagaatgc tctcataaat acaagcaagg agctgctagt
    60781 aaggttggaa ctaggagagg taaaacaacc gttacgatag gtttaaatcc gaaggacccc
    60841 atgctttcag ctgcttcaag tagagaattg tcaatactgt tcattgttcc agcaacatat
    60901 agaaatacca gtgggaatag ttgcagtgta aagacaagta caattccttt gaatccataa
    60961 atatcgatag ctggaagata aagggcattt gtcaaaaatt tagtgatgac ctcatttcgt
    61021 cccagcaaga gaatccagga gtaggctcct acgaaaggag ctgacatgga agcaatgata
    61081 atcaatattt gtagaaattt cttccccttg aagtcataca tagagaagag ataagctaat
    61141 agggttccta caactaagga agtgacagta gcggtaatgg aaaccctgaa actgttgact
    61201 agtgtctcag agtagtaggc tttactaaag aaagtgacaa aattagctag tgagaattgt
    61261 ccttcatgta taagtgcttg cttgagcacg gtaacgatag gataaacgag aaagacaaga
    61321 taggtaagaa agaggaagaa agaggaggct gtccaaatat ttagtttttt acattccatg
    61381 gttgactcct tttatcaggt tttgggaacc atctgcagaa aagatgttta atttttgcgt
    61441 attgattcgt agacgaatac gattgccttt ttgtagatct tcttcaaaag ttgattcttc
    61501 actaacttga atttttgagg caaaacctgt ctcaatgaaa tactccgtat ttagtccaag
    61561 atagacgcta tcgctaatag ttccttcgat atctccagat tcatctttga taaactcttc
    61621 gggacgaatg cttacatgaa tagcttgctc ctcaacctga tcaagagcta gcattcgaag
    61681 ggcatagcca tctgaaaaga cgatataagc gccgtcgctc cgtttttcaa gattggcagg
    61741 gataatattt gtgcgtccga taaaggttgc cacaaactca ttagctggtt tatgatagag
    61801 ttcttttggt cggccgattt gttggatcac cccatctttc ataacagcaa tttggtctga
    61861 aatagccatg gcttcttctt ggtcgtgggt tacataaaca gttgtaattc ccacttcgtg
    61921 ttggatttct cggatggttt gacgcatatc caagcgaagt ttggcctcca gattactaag
    61981 tggctcgtcc atgaggagaa cacttggatt aaccgctaag gcgcatgcca aggtgacacg
    62041 ttgttgttgt ccaccactga gtttatcggg ctttcgatcc gcatattgag caatttgcat
    62101 gagttcaaga tacttgttgg tctgttgaat caattcttct tttggaacct tcttttgcat
    62161 aagaccaaaa gcaacgttgt ctcggacagt caaatgtggg aaaatagcgt agttttggaa
    62221 aaccagcccg atattgcgtt tgctgggttc catattattg atttttgtat catcgaagta
    62281 aaattctcca tctttgatac tgttgaaacc tgcaatcata cgaagaaggg tcgttttccc
    62341 acatcctgaa gctccaagaa gggtaaagag acttcctttt ggaattgtaa tgttcaaatt
    62401 ctcaataaca gggacatcgt ggtagatttt tttggcgtta ataatttcga tctcactcat
    62461 agtgaacctc ttttactgtt tagattggat atctgtaaag acttcgttgt atttcttaac
    62521 gatatctgat ttattcttga tgacataatc ataatcttaa gtgagtgttt tgattttgtc
    62581 aattggtttc atgttttcgc ttgttttagc atttttacga acaggacggt tagtagtggt
    62641 tgtaccaagt gtatcttgta cttcttgaga gataataaaa tcgataaatt tcttggcatt
    62701 ttccatattt ttagattttt taacgatagc agcactagaa ggtaggaaga cggttccttc
    62761 ttttggatag actaccttaa tgttagctcc gtcatttaag agtttaactg ctggatcttc
    62821 ataagagaga ccaacagtca tttctccatc agcgactgct ttatagacac cagatgaact
    62881 tgaaccgatt ttatagtata ttgaaactag aatagtacac atctacttct aaaacattgt
    62941 tagaaatcga tttgactgtc ctgattaatt tgtcctgttc ttatttcatt ttactatacc
    63001 atcaataagt gtgaaaagat cttttacata agaccaagcc ttatcatctt tgtaaccacc
    63061 ttgagcttgt agcatatttg ttaattgagc aaaggcgcta gaagagtttg ctgggtcagc
    63121 agttgcgatt tttcctttta gttcaggttt gagaaggtcg ctatatcctt cgatgttcat
    63181 gcctttagtt aaatcagggt ggacgattaa aacattacca tctagtgtat aaggagtaga
    63241 gaagccagtt gtgttttgat attctttgat aacattatca ttttcttttg aaatatagtt
    63301 ttcaaagagt tctccgtggg tagcatattg tgtataagaa ccaccaaaga taacatcagc
    63361 tacaggaact tctttttctg actctagttt tttgaaaagt tctccagtac cagcttgaat
    63421 cagttctatt ttgataccat atttttcttc aaaggcagga atagttgctc caattaagcc
    63481 ttctgagttt ggtgaataaa cgactagcga accaccgtct cctttatcag atgaactgtc
    63541 atcggcagat tcattagaag aacaagcagc ataatacatc catttctttt tcatgatgga
    63601 tacctccgtt gtgttattta agtttatttt aaaacaatgt aagcgttttt aaaacctaca
    63661 attctattct atagtgtatt gaatctataa cagtacactt tgactgctaa aatatttcta
    63721 taaattaatt tgactttcct gatagagatg ttcacatctt atttcaattc actatattag
    63781 agtaaaattc tctacaaaaa gaagaacagc ctatttgact attcttccga gtgatttcaa
    63841 tttctttggg gaaatatgga gatacttttt aaatactttg gcaaaatatt tatagtctga
    63901 aaatccaact tggtcagaga tagcgcttaa aggggagttg ggagattcag ccatcttatc
    63961 tatagcttgt ttcaggcgat attgtaagat atattcattt agagtcatgg ggaagtcttc
    64021 tttgataacc ttatatagat gcttgttatc tgcaaatagc tagagcattt caaggaaatg
    64081 aactagaaat aacaattaat atggtggttc agaaatacct tttgataatc aataagatct
    64141 tcaggatgaa gtgcgttgac tccatccatt tcatatttcc gatttaataa acgatatttg
    64201 ttttcaccaa attgatgaaa agggagtagt tgaacttggt cgatatttaa tgagttaaat
    64261 agagtagcga atttttctgc atcctctaaa ctattgttaa aattaggaat aactgggatt
    64321 cttaaaacga tagttttatt ttgagaaaaa gcataatgaa tgtttttaat aatcatttga
    64381 ttaaaaaccc cagtcacttt tttatgtttt atagaattat aatgttttag gtctgtgtag
    64441 ataaaatcca catattgaat taaatcgata aatttttcat gatcaacaaa ggcagtagtt
    64501 tcaatggcag tgtgtatgtg atgttcttta gctgatttta agatggcttt agcaaattca
    64561 aactgagcaa atatttcacc tcctgataaa gttaaacctc caccggattc ttcgtaaaat
    64621 tctttgtctt ttaatacctc tgtaataatt tcttctacag tcttttcttc accgactaag
    64681 gtgaatttct ctcgttgagc atctttcatt ttttcaggtt tcattctttg agattcagga
    64741 ttagaacacc atggacagcg cagaggacat ccttttaaaa aaacagttgt acgaataccc
    64801 gggccgtcat gaattgaaaa gtgttgaata ttaaaaataa ttcctttaga tatttccata
    64861 agagttcctc ctcttcataa gtctatccta tcacaaaaac gaaagaaaaa caattacgaa
    64921 cgaaagttta atttgttgtt ttttgttttt tattttggta gaataaaacg gaggtgtaaa
    64981 atgaaaagat tggaacaaat tattaaatta gtatcagaat atgaaaagat cgacgttaat
    65041 acattatcgg aaaaattaaa tgtatcgaaa gtaacgatta gaaaagattt agataaatta
    65101 gagtcaaaag gtttattaca cagagagcat ggatatgctg tattaaatag tggagatgac
    65161 ttaaatgtac gtttgtcaat taattatgaa attaagagaa aaattgttca ggaagcagta
    65221 aaattggtgt cagataatga aacaataatg atagaatctg gatcgacctg tgctttactt
    65281 gctgaggaaa tttgcaagca aaaaagaaat gttacgattg taacaaattc attttttata
    65341 gcaaattttg tgagagctta tgattcatgt cgtattattg ttcttggtgg agagtttcag
    65401 aaggattcac aggttactgt gggaccttta ttaaaagaaa tgatacagac ttttcatgtg
    65461 catcaagctt ttgttgggac agatggttac gataaagaga tgggctttac aggaaaagat
    65521 ttaatgcgca gtgaggtagt tcaatatatt tcagcagcgt cggataaagt cattgtacta
    65581 actgactcaa gtaaatttga taaaaggggt acagtaagaa gatttgcttt aagtcaagtc
    65641 tatgaagtaa taacagacga aaaactttct aaacaaaata tagctacatt agaaaatgct
    65701 gggataatgg ttaaggtagt ttcgtaagag gttaagtgta tgaatcaaga taggaataaa
    65761 ctgctctcta aaattgctta tctgtattat attgaaaact taaatcagtc acaaatagca
    65821 gcaaaattag gaatttatag aacctctatt agtagaatgt taacagaagc aaggaatgca
    65881 ggaattgtta aaattgaaat agagaatttt gataccaata tgtttaagtt ggaaaattat
    65941 gtaaaagaaa aatatggtct ggaaagttta gaaattattc caaatgaatt tgatgataat
    66001 ccaacaattt tatctgaaag aatttctcaa gttgcagcag gtgtccttag gaatctaatt
    66061 gatgataata tgaaaattgg cttttcttgg gggaaaagtt taagtaattt agtagattta
    66121 attcacagta aaagtgtccg aaatgttcac ttctatcctc tagcaggtgg tcctagtcac
    66181 atacacgcta aataccatgt gaatacactg atttatgaaa tgtctagaaa atttcatgga
    66241 gagtgtacat ttatgaatgc aacgattgtg caagaaaata aattgttagc agatggtatt
    66301 ttgcaatcaa gatattttga aaatttgaaa aatagttgga aagatttaga tatagctgta
    66361 gtcggaattg gtgattttag caataaagga aagcatcaat ggttagacat gcttacagag
    66421 gatgacttta aagaattgac caaagttaaa actgtaggag aaatttgttg tcgatttttt
    66481 gattcaaaag gtaaagaagt ctatgaaaac ttacaggaaa gaacgatagc aatctctttg
    66541 gaagatttaa aaaatattcc tcaaagttta gctgttgctt acggtgatac gaaagtatct
    66601 tcgattcttt ctgtcttgcg tgctaattta gtaaatcatt tgattacaga caaaaataca
    66661 attttaaaag ttttggaaga agatggggat ttgactttta gagagattct aggtgagtga
    66721 aaatgataga ctgattcagt ttatcgtttt tctttttagt tgattgcaca tttgtgctta
    66781 tataaacaaa aatagtttat ctgttgtttt tggattgaca actttattat gtagttgtat
    66841 tctatagtta caaaagaaaa ttttaaaatt tcaaatgaaa aaagcttttt acatagtgaa
    66901 atgaggagga atttatggaa attattgttc cagatcaaat tatcatgggt ttaattttat
    66961 atgctggtga tgcgaaacaa catatttata aagcgttaga ttacataaaa aatggtacat
    67021 gtgaacggtg tgaagaagaa atccagttag ctgatgccgc cttattagaa gcccataatc
    67081 tacaaacaaa attcttggca caagaagcgt ctggtacaaa gacagaaatt acagctctct
    67141 ttgttcattc acaagatcat ctcatgacta gtatgacgga gattaattta atcaaagaaa
    67201 ttattagttt gagaaaagaa cttcataaaa aataatacta gagtattatc attgttatta
    67261 acatagagga ggaaaacata atggtgaaga ttggtttgtt ttgtgcagca ggtttttcta
    67321 ctggtatgct tgtaaataat atgaaaattg cagcgcaagc tagtggagtt gaggcagaaa
    67381 tagaggcgtt ttctcagtct aaattagcgg attatgcgcc aaatatagat gttgcactat
    67441 tgggtccaca agttgcttat acattagata aatcaaaaga aatttgtgat aagtgtgatg
    67501 ttccgatagc tgttattccg atgatggact atggtatgtt agatgggaaa aaagtattag
    67561 atttggccct atctttgatt agtgggtaag aaaaggagat ttattatggc aaagatggat
    67621 gttcagaaaa tcattgcacc gatgatgaag tttgtgaata tgcgtggcat tatagctcta
    67681 aaagatggga tgttagcaat tttgccattg acagtagttg gtagtttatt cttgattatg
    67741 ggacaattgc cgttcgaagg attaaataag agcattgcta gtgtttttgg agctaattgg
    67801 acagagccgt ttatgcaagt atattcagga acttttgcta ttatgggtct aatttcttgt
    67861 ttttcaattg cctattctta tgctaagaat agcggagtag aggctttacc agctggagtt
    67921 ctatctgtat ctgcattctt tattttacta agatcatctt atatccctaa acaaggtgag
    67981 gcgattgggg acgctattag taaagtttgg tttggaggcc aaggaattat cggtgctatc
    68041 attataggtt tggtagtagg aagtatttat accttcttta taaagagaaa aattgttatt
    68101 aagatgccag aacaagttcc acaagctatt gccaaacagt ttgaagcaat gattccagca
    68161 tttgtaattt tcttatcttc tatgattgta tatattttag cgaagtcatt gactaatggc
    68221 ggaacattca tagaaatgat ttattctgct attcaagttc cgttgcaagg tttaactgga
    68281 tctttgtatg gtgctattgg aattgcattc tttatatcat ttttgtggtg gtttggtgtt
    68341 catgggcaat cggtagtaaa tggagtagtg acagctctgc ttttatctaa tcttgatgct
    68401 aataaagcta tgttagcctc tggtaatcta tcattagaaa atggtgcaca tattgttact
    68461 caacaatttt tagattcatt tttaattcta tcaggttcag ggattacgtt tggtcttgta
    68521 gttgccatgc tttttgcagc aaaatcaaaa caataccaag ccttaggaaa agttgcagct
    68581 tttccagcaa tatttaacgt aaatgagcca gttgtatttg gatttccgat tgtcatgaat
    68641 ccagttatgt ttgtaccttt cattcttgtt cctgtacttg cagctgtgat agtatatgga
    68701 gctattgcaa caggtttcat gcagccattc tcaggggtaa cattgccttg gagtacacca
    68761 gctattctat caggattttt ggtgggtgga tggcaaggtg ttgtgactca gttattagta
    68821 ttggtgatat ctacagtggt ttactttcca ttctttaaga tacaagatcg tttagcttac
    68881 caaaatgaaa tcaaacaatc ttagaggtat ttgtgtgtta ctgttaaact cacacatttg
    68941 tgctaaaaat tagagagtta aaatttttct agttaaaagc ttgaaaattt ctataaaaat
    69001 cggtattata ttttcgaaag aaataaaaat attttcgaaa gaaaggtgct tacgatggta
    69061 aatacagaag tagcaagaac aacaatcaaa acagaatatt ttggcagcct tactgaaagg
    69121 atgaacaaat atcgagaaga tgttttaaat aaaaaacctt atattgatgc tgagagagca
    69181 gttctagcaa cacgcgccta tgaacgatac aaggaacaac ctaatgtcct aaaacgtgca
    69241 tatatgctga aagaaatttt ggaaaatatg tctatctata ttgaagaaga atctatgatt
    69301 gcgggaaatc aagcttcttc caataaagat gctcctattt ttccggaata tacgctagaa
    69361 tttgttctca atgagttgga tctttttgaa aagcgtgatg gagatgtttt ctatattaca
    69421 gaagaaacaa aagaacaact tagaagtatt gctccgtttt gggaaaataa taatttacgt
    69481 gctagagctg gtgccttatt acctgaagaa gtgtcagttt atatggaaac aggattcttc
    69541 ggtatggaag gtaagatgaa ttctggagat gctcacctag cagttaacta tcagaaactt
    69601 ttgcaatttg gtttaagagg ttttgaagag cgggctcgta aagcaaaagt agctctagat
    69661 ttaacagatc cagcaagtat tgataaatat catttttacg actctatatt tatcgtaatc
    69721 gatgctatta aagtatatgc aaagcgcttt gttgctcttg ctaaaagttt agccgaaaat
    69781 gcaaatccta aacgtaagaa agaattactt gagattgcag atatttgctc tagagtccca
    69841 tatgaaccgg caactacttt tgcagaagct attcaatcag tttggtttat tcaatgtatt
    69901 ttacaaattg aatctaatgg ccactctctt tcatatggcc gttttgatca atatatgtat
    69961 ccatatatga aggctgattt agaaagtggt aaagaaacag aagatagcat tgttgaacgt
    70021 ctgacaaatc tttggattaa gacaattaca attaataagg ttcgcagtca atcacataca
    70081 ttttcttcag caggaagtcc tttatatcaa aatgttacaa ttggtggaca gactcgagat
    70141 aagaaggatg ctgttaaccc attatcttat ttggtattaa aatcagttgc acaaacccat
    70201 ctaccgcaac ctaatctaac tgtacgttac catgcaggtt tagatgctcg tttcatgaat
    70261 gagtgtattg aagtgatgaa acttggtttt ggtatgcctg catttaataa tgatgagatt
    70321 attattcctt cttttattgc aaaaggagta ttggaagatg atgcttatga ttacagtgcc
    70381 attggatgtg ttgaaacggc agttccaggg aaatggggct atcgttgcac aggtatgagt
    70441 tatatgaact tccctaaggt tctacttatc acgatgaatg atggaattga tccggcttcg
    70501 ggtaaacggt ttgcaccaag ctttggtcat tttaaggata tgaagaactt ttctgaatta
    70561 gaaaatgctt gggataaaac actaagatat ttgacacgaa tgagtgttat tgttgaaaat
    70621 tctattgatt tatcattgga acgagaagtt cctgatattc tatgttcagc attgactgat
    70681 gattgtattg gtcgtggaaa acaccttaaa gaaggtggag cagtatatga ttatatatca
    70741 ggattgcaag ttggaattgc aaatttgtcg gattcgttag ctgcaattaa aaaattggtg
    70801 tttgaggaag aacgtataag cccaagtcag ctttggcatg cactggaaac agattatgcc
    70861 ggagaagaag gtaaggtcat tcaagaaatg ttgattcatg atgcacctaa gtatggtaat
    70921 gatgatgatt atgctgacaa attggttact gctgcttatg acatttatgt tgatgaaatt
    70981 gctaaatatc ctaatacacg ttatggaaga gggcctattg gaggaattcg ttattcagga
    71041 acatcttcta tatcagccaa cgtagggcag ggacgtggaa cattagcaac tccagatgga
    71101 cgcaacgcgg gtacaccgtt agcagagggt tgttcaccat cacataatat ggatcaacac
    71161 ggccctacat ctgttttaaa atctgtttca aaattaccaa cagatgaaat cgtaggtggg
    71221 gttctcttaa atcagaaagt aaatcctcaa acgttagcca aagaagaaga taaattaaaa
    71281 ctaattgctt tgttacgaac attctttaat cgtttacatg ggtaccatat tcaatacaat
    71341 gttgtttcca gagagacgtt gattgacgct cagaaacatc ctgaaaaaca cagagactta
    71401 attgttcgtg ttgcaggata ctctgcattc ttcaatgttc tttctaaggc aacccaagat
    71461 gacattatag gacgtactga gcatactttg taaaataaag aggttctttt tatggaattt
    71521 atgcttgaca cattaaattt agatgagatt aaaaagtggt ctgaaatttt gccgctagct
    71581 ggggtaactt caaatcccac tattgcaaaa agagagggtt ctattaattt ttttgaacga
    71641 atcaaagatg taagagaatt gattggctct acaccctcta ttcatgttca ggtgatttct
    71701 caagattttg aaggcatctt aaaggatgct cataaaattc gaagacaagc aggagatgat
    71761 atatttatca aagtacctgt tactccagct ggattacgtg caataaaggc gctaaaaaaa
    71821 gagggctacc atatcactgc aacagctatt tatacagtta ttcagggatt attagctatc
    71881 gaagcaggag cggattacct agctccatat tataatagaa tggaaaatct gaacattgat
    71941 tcaaattctg tcattcgtca attagctctt gctattgata gacagaactc tcctagtaag
    72001 attttagctg catcctttaa aaatgtagca caagtaaata atgctttagc tgcaggtgcg
    72061 catgctgtta cagcaggagc ggatgttttt gaatcagctt tcgccatgcc atctatccaa
    72121 aaggcggttg atgatttttc tgacgattgg tttgttattc aaaatagtcg ttccatttag
    72181 atagagagga aatacatatg agaatttttg ctagtccttc tagatatatt cagggggaaa
    72241 atgccttgtt tgaaaatgcc aaatcaattt tggatttggg aaattaccct attctattat
    72301 gcgatcagtt ggtttatgat attgttggaa aacgatttga agattaccta cataggtatg
    72361 gtttccatat tgttctggcg ctatttaatg gtgaagcttc tgacaatgaa atcaatcgag
    72421 ttgttgcctt ggctgagaaa gaaaattgtg atagtattat cggtcttggt gggggaaaga
    72481 cgattgatag cgcaaaagct attgcagatt tgattgaaaa gcctgttatt attgctccaa
    72541 caattgcatc gaccgacgca cctgtatctg ctttatctgt tatttataca gatgaaggtg
    72601 catttgatca ttatctattt tattctaaaa atccagattt agttttggtt gatacaaaag
    72661 ttatttcaca agcccctaag cgtttattag cgtctggtat tgcagatggt ttagcaactt
    72721 gggttgaggc gcgtgcggtt atgcaggcaa atggaaaaac tatgttggga caacagcaaa
    72781 cattggctgg agttgcaatt gcgaagaaat gtgaagaaac gctgtttgca gatggtttac
    72841 aggctatggc agcttgtgaa gctaaagtgg tgacaccagc attagaaaat attgttgaag
    72901 ctaatacttt attgagtggt ctaggttttg aaagtggagg attagctgcg gcgcatgcaa
    72961 ttcataatgg ttttactgca ttgacaggtg acattcatca tttaacacat ggtgaaaaag
    73021 tagcttatgg aactttagta caactattat tggaaaatag acctaaagaa gaacttgata
    73081 agtatattga gttttacaaa aaaattggta tgccaacaac tctaaaagaa atgcatttgg
    73141 atcaagttgg atatgatgat ttaataaaag ttggtaaaca agcaactatg gagggtgaga
    73201 caattcatca gatgccgttt aagatttcgc cttcagatgt tgctcaagct attatcgctg
    73261 tagatgccta tgtaaattca aaataaacaa taaggactac tgttttccaa atggtagtct
    73321 tttattgatc cctgtattga attctataga agattgaaat aggatgagaa caaatcgatt
    73381 gggaaagtaa aattaatttc tataaatgtt ttagcaattg tttcgtacta tttcagattc
    73441 agtctactat acgttcttca taaatcaaaa agcgacatag gtagtcggct atttattgtg
    73501 aatacattaa ttagcattcc agttttatct tcggtctaaa ataagtattt tgtgctatac
    73561 gagataagct tcttgactta ctccttgatt tactgcataa caatgggata aaaagtggga
    73621 gatagagcaa ttcatagtca tcaaaattaa tgagatacag tatacagttt ttcctttaaa
    73681 cacatttcaa attccctcaa aaatggtata atagtaacat cacaaaattg gagagagacc
    73741 atgagttttt ataatcataa agaaattgag cctaagtggc agggctactg ggcagaacat
    73801 catacattta agacaggaac agatgcatca aaacctaagt tttatgcgct tgatatgttc
    73861 ccttatccgt ctggagctgg tctgcacgta ggacacccag aaggttatac tgcaaccgat
    73921 atcctcagtc gttacaaacg tgcgcaaggc tacaatgttc ttcacccaat gggttgggat
    73981 gcttttggtt tgcctgcaga gcaatacgct atggatactg gtaatgaccc agcagaattt
    74041 acagcggaaa acattgccaa cttcaaacgt caaatcaatg cgcttggatt ttcttatgac
    74101 tgggatcgtg aagtcaacac aacagatcca aactactaca agtggactca atggattttc
    74161 accaagcttt acgaaaaagg cttggcctat gaagctgaag tgccagtaaa ctgggttgag
    74221 gaattgggaa ctgccattgc caatgaagaa gtgcttcctg acggaacttc tgagcgtgga
    74281 ggctatccag ttgtccgcaa accaatgcgc caatggatgc tcaaaatcac ggcttacgca
    74341 gagcgcttgc tcaatgactt agatgaacta gattggtcag agtctatcaa ggatatgcaa
    74401 cgcaactgga ttggtaaatc aactggtgcc aatgtaactt tcaaagtaaa aggaacagac
    74461 aaggaattta cagtctttac tactcgtccg gacacacttt tcggtgcgac tttcactgtc
    74521 ttggctcctg aacatgaatt agtagacgct atcacaagtt cagagcaagc agaagctgta
    74581 gcagactata aacaccaagc cagccttaag tctgacttgg ttcgtacaga ccttgctaag
    74641 gaaaaaactg gtgtttggac aggtgcctat gccatcaacc ctgtcaatgg taaggaaatg
    74701 ccaatctgga ttgcggacta tgttcttgct agttatggaa caggtgcggt tatggctgtg
    74761 cctgcccacg accaacgtga ctgggaattt gccaaacaat ttgaccttcc aatcgtcgaa
    74821 gtacttgaag gtggaaatgt cgaagaagct gcctacacag aggatggcct gcatgtcaat
    74881 tcagacttcc tagatggatt gaacaaagaa gacgctattg ccaagattgt ggcttgcttg
    74941 gaagaaaaag gctgtggtca ggagaaggtt acctaccgcc tccgcgactg gctctttagc
    75001 cgtcaacgtt actggggtga gccaattcca atcattcatt gggaagatgg aacttcaaca
    75061 gctgttcctg aaactgaatt gccgcttgtc ttgcctgtaa ccaaggatat ccgtccttca
    75121 ggtactggtg aaagtccact agctaacttg acagattggc ttgaagtgac tcgtgaagat
    75181 ggtgtcaaag gtcgtcgtga aactaacacc atgccacaat gggctggttc aagctggtac
    75241 tacctccgct atattgaccc gcacaatact gagaaattgg ctgatgagga cctcctcaaa
    75301 caatggttgc cagtagatat ctacgtgggt ggtgcggaac atgctgtact tcacttgctt
    75361 tatgctcgtt tctggcataa attcctctat gacctcggtg ttgttccgac taaggaacca
    75421 ttccaaaaac tctttaacca agggatgatt ttgggaacaa gctaccgtga ccaccgtggt
    75481 gctcttgtgg caaccgacaa ggttgaaaaa cgtgatggtt ccttctttca tatagaaaca
    75541 ggggaagagt tggagcaagc gccagccaag atgtctaaat cgctcaagaa cgttgttaac
    75601 ccagatgatg tggtggaaca atacggtgcc gatacccttc gtgtttatga aatgtttatg
    75661 ggaccactcg atgcttcgat tgcttggtca gaagaaggtt tggaaggaag ccgtaagttc
    75721 cttgaccgag tttaccgttt gattacaagt aaagaaatcc ttgcggaaaa caatggtgct
    75781 cttgacaagg cttacaacga aacagtcaaa gctgttactg agcaaattga gtctctcaaa
    75841 ttcaacacag ctattgccca acttatggtc tttgtcaatg ctgctaacaa ggaagataag
    75901 ctttatgttg actatgccaa aggctttatt caattgattg caccatttgc acctcacttg
    75961 gcagaagaac tctggcaaac agtcgcagaa acaggtgagt caatctctta tgtagcttgg
    76021 ccaacttggg acgaaagtaa actggttgaa gacgaaatcg aaatcgttgt ccaaatcaaa
    76081 ggtaaagtcc gtgccaaact catggtcgct aaagacctat cacgtgaaga attgcaagaa
    76141 attgctctag cggatgaaaa agtcaaagca gaaattgacg gtaaggaaat cgtgaaagtg
    76201 attagtgtac caaataaatt ggttaatatt gttgtaaaat aaccaattta tttgctgatt
    76261 tccaacctca aacagtttcc caaactgttt gagccaacta aactcgttaa tatcgttgtg
    76321 aaataaggta ggaatccttc agagtagaat ctggaggatt ttttgaatct tcttatgaaa
    76381 gtatggtata ctatgggcaa ctataaagtt tgaaaagtga aaaaaggaga aagctatgcc
    76441 agtaaatgaa tatggtcaaa tgattgggga gtcaatggaa ggttatacac caggtgaact
    76501 gccttctatt gatttcttag aagggcgtta tgctaggata gaggctcttt cagtggaaaa
    76561 gcatgcggag gatttgctag ctgtttatgg cccggatact cctcgggaga tgtggaccta
    76621 cctttttcag gagccagtag cagatatggg ggagctggtt agccttttac atcagatgtt
    76681 ggctcgtaag gaccgttttt actatgcaat catagacaag gcgactggta aggctttggg
    76741 atctttttct ctcatgcgca ttgaccagaa taaccgagta atagaagtcg gagcagtcac
    76801 tttttctcca gagctaaggg gtacacggat aggaactgaa gctcagtatc tcctagctcg
    76861 ctatgttttt gaggagctaa actatcgtcg ctacgagtgg aaatgcgatg ccttaaatct
    76921 gccatccaga cgagctgcgg agcgtttgag ctttatttat gaaggaacct tccgtcaggc
    76981 agtggtttat aagggacgta cgagagatac ggattggttg tctatgattg ataaggactg
    77041 gcctcaagtc aaagatcgtt tggaaacatg gttgcgtcct gaaaattttg ataaaaatgg
    77101 acagcagtac aagagcttga gagaacttta agaggtgttg agatgattac tattaaaaag
    77161 caagaaattg tcaagctaga ggatgtttta catctctatc aggctgtcgg ttggacaaat
    77221 tatacccatc aaccagagat gctggagcag gccttatctc attcattagt aatttatctg
    77281 gcacttgatg gtgatgctgt ggtgggcttg attcgtttgg ttggagatgg attctcatca
    77341 gtattggttc aggatttaat cgttttacca atctatcagc gtcaaggaat tggtagtgcc
    77401 ttgatgaaag aggctttaga ggattacaaa gatgcctatc aagtccagct ggtgacagaa
    77461 gagacagaaa gaaccttggg cttctatcgt tctatgggct ttgaaatctt atccacctat
    77521 aattgtatag ggatgacttg gatgaatcgt aaaaaataac aaaacttgtt ttttcttaag
    77581 caaaatttaa ggatggtcta gtattatata gtcattaaat aaagacctcc taactttatt
    77641 taataaaatc ctaaactttt ttcatcacaa tctcctaatg aagccaccca atcaggtggc
    77701 ttttttgcgt ggtgaggtgc tggtgataga aattttttgc aaaatagtaa aattttagaa
    77761 aagttaagct agttttaagt ttcgtcttgt atcatgtagt tattaaataa agacctccta
    77821 actttattta ataaaatcct aaacttttct ttttcataat aatctccctt aacttcaccc
    77881 aatcaggtgg agttttttag ctctatttca ggcttttggg gactattcta aaaataattt
    77941 ttcgatattt ttcggtattt ttcggatttt ggtcggggaa ttggcgggga cttttttagc
    78001 gaatataact aagaaatagg tctgtggtcg cttcagctag ttcaaactca atttgattgt
    78061 aagtgactgt taattgaaga actggaacta ctgtaataat gattttgctt gtctagtagt
    78121 ggcgtattaa atgagaagta acatgtaaga ttgtctcttc gtttacgaaa tcaaaatttc
    78181 tatgaaattg atagaatccc taacgttctc ttaatcttaa ccgtcttgtc gtacagcggt
    78241 tgaagaaaat gtaaaccttt gacaaaattc gtgaactatg ggataataaa aaggaattga
    78301 gtactagttc tatatcatag gctagaaaag accccaagct cacgaccaaa taagcttgag
    78361 gtcttttttg acactatttg tccttgttta gccatttatc gactatacga agaacgacac
    78421 cgaccacaat tggtccgatg atagttttga gtactaattc catcatgggc tatctcacct
    78481 cctttcgtag gcggtgtagc agtgtcgtag aatattatac cacataagtg ctaaacttag
    78541 gagtcaccca atcaggtggc ttttttgttt gtggcttggt tttttgatat aatagagcca
    78601 tgagtagaat tttagataat gagataatgg gggatgagga gttagtagaa cgcacgctcc
    78661 gtcctcagta tttacgtgaa tatatcggac aggataaggt caaggaccag ctacaaatct
    78721 ttattgaagc tgccaaaatg cgggatgaag cgctggatca tgtgctctta tttgggcctc
    78781 caggtctcgg gaaaacgacc atggcctttg ttattgccaa cgaactggga gtcaatctta
    78841 agcagacgtc gggtccagtc attgaaaaag ccggagatct ggtagctatt ttgaatgagt
    78901 tagagcctgg ggatgtactt tttattgatg agatccatcg tttgccaatg tcagtggaag
    78961 aggtgcttta tagtgctatg gaggacttct acatcgatat tatgattggg gctggtgagg
    79021 gtagtcgtag tgttcatttg gagttaccac cttttacctt gattggtgcg acgactcggg
    79081 ctggtatgct ctccaatccg ctacgggcac gttttgggat tacaggccat atggagtatt
    79141 atgcccatgc tggcttgaca gaaattgtcg agcggacggc agatattttt gagatggaaa
    79201 tcactcatga ggcagcatct gagttggccc tacgtagtcg tgggacccct cgtattgcca
    79261 atcgtctcct caagcgcgtg cgcgattttg cccagataat ggggaatggg gtaattgatg
    79321 atattattac cgataaggct ttgactatgc tggatgttga ccatgaaggt ttggactatg
    79381 tggatcaaaa aatccttcgt accatgattg agatgtacag tggaggacct gttggtctag
    79441 gaactctttc tgtgaatatc gccgaagagc gtgagacagt tgaagatatg tatgagcctt
    79501 acttgattca aaaaggtttt atcatgcgga cacggtctgg acgggtggcg actgctaagg
    79561 catatgagca cttaggttat gaatacagtg aaaaataagc aagaaatctt agaggctttt
    79621 agagaaaatc cagatatgat ggccattctg acgatcatcc gagaccttgg tctgaaagac
    79681 tcgtggttgg cagcaggttc tgtcagaaat ttcatttgga atcttttgtc agacaaatcc
    79741 ccttttgatc atgaaacaga tatagatgtg attttctttg atccagattt ttcttatgag
    79801 gaaaccttat tactggagaa aaagctgcga gaggattttc ctcagtacca gtgggaattg
    79861 aaaaatcagg tctatatgca tcagcacagt cctcacactg cttcctatac cagttctcgt
    79921 gatgctatga gtaagtatcc agaacggtgt acgacagttg gactgcgctt gaatgaagaa
    79981 tcagattttg aactctatgc accttatggt ttggaggata ttttgaattt tcaagttcgt
    80041 ccaactcctc atttcttaga aaatgaagac cgaatggaac tctatcaaac acgtttatcc
    80101 aagaaaaatt ggcaggagaa atggaaaaat ttgattttta aaaatactta aggaaacttt
    80161 aagctaggga gtgtacacta agttcataag ttaagaagac cttaacttaa actcctaaaa
    80221 ctttttcata ataatctccc tataaaaata aagtcgccca atcaggcggc ttattttttt
    80281 gaaaaatggg cttggtgcct gagaataaat agcttagtga tagaagaaaa tggggaaata
    80341 tggtataatg aaacgataga tttttgaata ggaataagat catgtttgga ttttttaaga
    80401 aagataaggc tgtggaagta gaggttccga cacaggttcc tgctcatatc ggcatcatca
    80461 tggatggcaa tggccgttgg gctaaaaaac gtatgcaacc gcgagttttt ggacacaagg
    80521 cgggcatgga agcattgcaa accgtgacca aggcagccaa caaactgggc gtcaaggtta
    80581 ttacggtcta tgctttttct acggaaaact ggacccgtcc agatcaggaa gtcaagttta
    80641 tcatgaactt gccagtagag ttttatgata attatgtccc ggaactacat gcgaataatg
    80701 ttaagattca aatgattggg gagacagacc gcctgcctaa gcaaaccttt gaagctttaa
    80761 ccaaggctga ggaattgact aagaacaaca caggattgat tcttaatttt gctcttaact
    80821 atggtggacg tgctgagatt acacaggcgc ttaagttgat ttcccaggat gttttagatg
    80881 ccaaaatcaa cccaggtgac atcacagagg aattgattgg taactatctc tttactcagc
    80941 atttgcctaa ggacttacga gacccagact tgattatccg tactagtgga gaattacgtt
    81001 tgagcaattt ccttccatgg cagggagcct atagtgagct ttattttacg gacaccttat
    81061 ggcctgattt tgacgaagca gccttgcagg aagctattct tgcctataat cgtcgccatc
    81121 gccgatttgg aggagtttag gaggaaatat gacccaggat ttacagaaaa gaaccttgtt
    81181 tgcagggatt gccctggcta ttttcctacc aattttaatg attgggggcc tcttgcttca
    81241 gatagcaatc ggaatcatag ccatgctagc catgcatgaa cttttgaaga taagaggtct
    81301 agcgaccatg acgatggagg gcctcttgac tctctttgca acctttgcat taaccattcc
    81361 cttggagaat tacctgactt ttttgccagt tgatgggaat gtggttgcct atagtgtttt
    81421 gatttcaatc atgttaggaa cgaccgtttt tagcaagtct tatacgattg aggatgcggt
    81481 tttccctctt gctatgagct tctacgtggg ctttggattt aatgctttac tagatgctcg
    81541 tgttgcaggt ttggacaagg ctctcttagc cttgtgtatc gtctgggcga cagacagtgg
    81601 tgcctatctt gttgggatga actatgggaa acgaaagtta gcaccaaggg tatcgcctaa
    81661 taaaaccctt gagggtgcct tgggtggtat tttaggagca attttagtaa ccattatctt
    81721 tatgatagtt gacagtacag ttgctcttcc atatggaatt tacaagatgt cagtctttgc
    81781 tattttcttt agcattgctg gacaatttgg tgatttacta gaaagttcga tcaaacgtca
    81841 ttttggtgtt aaggattctg ggaaatttat ccctggacat ggtggtgttt tggatcgttt
    81901 cgatagtatg ttgcttgtat ttccaatcat gcacttattt ggactctttt aatcaaaaga
    81961 cggaggaaac gctatgctcg gaattttaac ctttattctg gttttcggga ttattgtagt
    82021 ggtgcacgag ttcgggcact tctactttgc caagaaatca gggattttag tacgtgaatt
    82081 tgccatcggt atgggaccta aaatttttgc tcacattggc aaggatggaa cggcctatac
    82141 cattcgaatc ttgcctctgg gtggctatgt ccgcatggcc ggttggggtg atgatacaac
    82201 tgaaatcaag acaggaacgc ctgttagttt gacacttgct gatgatggta aggttaaacg
    82261 catcaatctc tcaggtaaaa aattggatca aacagccctc cctatgcagg tgacccagtt
    82321 tgattttgaa gacaagctct ttatcaaagg attggttctg gaagaagaaa aaacatttgc
    82381 agtggatcac gatgcaacgg ttgtggaagc agatggtact gaggttcgga ttgcaccttt
    82441 agatgttcaa tatcaaaatg cgactatctg gggcaaactg attaccaatt ttgcaggtcc
    82501 tatgaacaat tttatcttag gtgtcgttgt tttttgggtt ttaatcttta tgcagggtgg
    82561 tgtcagagat gttgatacca atcagttcca tatcatgccc caaggtgcct tggccaaggt
    82621 aggagtacca gaaacggcac aaattaccaa gattggctca catgaggtta gcaactggga
    82681 aagcttgatc caagctgtgg aaacagaaac caaagataag acggcaccga ctttggatgt
    82741 gactatttct gaaaagggga gtgacaaaca agtcactgtt acacccgaag atagtcaagg
    82801 tcgttacctt ctaggtgttc aaccgggggt taagtcagat tttctatcca tgtttgtagg
    82861 tggttttaca actgctgctg actcagctct ccgaattctc tcagctctga aaaatctgat
    82921 tttccaaccg gatttgaaca agttgggtgg acctgttgct atctttaagg caagtagtga
    82981 tgctgctaaa aatggaattg agaatatctt gtacttcttg gcaatgattt ccatcaatat
    83041 tgggattttt aatcttattc cgattccagc cttggatggt ggtaagattg tgctcaatat
    83101 cctagaagcc atccgccaca aaccattgaa acaagaaatt gaaacctatg tcaccttggc
    83161 cggagtggtc atcatggttg tcttgatgat tgctgtgact tggaatgaca ttatgcgact
    83221 cttttttaga taatcgagga atattatgaa acaaagtaaa atgcctatcc caacgcttcg
    83281 cgaaatgcca agcgatactc aagttatcag ccatgctctt atgttgcgtg ctggttatgt
    83341 tcgccaagtt tcagcaggtg tttattctta tctaccactt gccaaccgtg tgattgaaaa
    83401 agctaaaaac atcatgcgcc aagaattcga aaagattggt gctgttgaga tgttggctcc
    83461 aacccttctt agtgcagaat tgtggcgtga atcaggtcgt tacgaaacct atggtgaaga
    83521 cctttacaaa ctaaaaaacc gtgaaaaatc agactttatc ttaggtccaa ctcacgaaga
    83581 aacctttaca gctattgtcc gtgattctgt taaatcttac aagcaattgc cactcaacct
    83641 ttatcaaatt cagcccaagt atcgtgatga aaaacgccca cgtaatggac ttcttcgtac
    83701 acgtgagttt atcatgaagg atgcttatag tttccacgct aactatgata gtttggatag
    83761 tgtttatgat gagtacaaag cagcctatga gcgtattttc actcgtagtg gtttagactt
    83821 caaggctatt attggtgacg gtggagccat gggtggtaag gatagccaag aatttatggc
    83881 cattacatct gctcgtacag accttgaccg ctgggttgtc ttggacaagt cagttgcctc
    83941 atttgacgaa attcctgcag aagtgcaaga agaaatcaag gcagaattgc tcaaatggat
    84001 agtctctggt gaagatacca ttgcttactc aagtgagtct agctatgcag ctaacttaga
    84061 aatggcaaca aacgagtaca aaccaagcaa ccgtgttgtc gctgaagaag aagttactcg
    84121 tgttgcaacg ccagatgtta aatcaattga tgaagttgca gccttcctca atgttccaga
    84181 agaacaaacg attaaaaccc tcttctacat tgcagatggt gagcttgttg cagcccttct
    84241 agttggaaat gaccaactca acgaagtcaa gttgaaaaat cacttgggag cagatttctt
    84301 tgacgttgct agcgaagaag aagtggcgaa tgttgttcaa gcaggatttg gttcacttgg
    84361 accagttggt ttgccagaga atattaaaat tattgcagat cgtaaggtgc aagatgttcg
    84421 caatgcagtt gtcggtgcta acgaagatgg ctaccacttg actggtgtga acccaggccg
    84481 tgattttact gcagaatatg tggatatccg tgaagttcgt gagggtgaaa tttccccaga
    84541 tggacaaggt gtccttaact ttgcgcgtgg tattgagatc ggtcatattt tcaaactcgg
    84601 aactcgctac tcagcaagca tgggagcaga tgtcttggat gaaaatggtc gtgctgtgcc
    84661 aatcatcatg ggatgttacg gtatcggtgt cagccgtctt ctttcagcag tgatggagca
    84721 acacgctcgc ctctttgtta acaaaacgcc aaaaggtgaa taccgttacg cttggggaat
    84781 caatttccct aaagaattgg caccatttga tgtgcatttg attactgtca atgtcaagga
    84841 tgaagaagcg caagccttga cagaaaaact tgaagcaagc ttgatgggag ctggttatga
    84901 agtcttgaca gatgaccgta acgaacgtgt cggtgttaaa tttagcgata gtgacttgat
    84961 tggtcttcca atccgtatca ctgttggtaa aaaagcggcc gatggcattg tagaagttaa
    85021 gatcaaggca actggtgaca ccattgaggt tcatgcagat aacgtgcttg aaacgcttga
    85081 aatcctaagc aagaaataaa aactataatc agaagaaaaa caaggaaaaa atgtaactag
    85141 tttttacctt gttttttctg tataatggga gaaatgagta gataaagagg taaatgttat
    85201 gctaagattt ccaaaggatt ttgtctgggg atcctctact tctggaccgc agacagaagg
    85261 acgtgtagct ggtgacggta agggagacaa tctctgggat tactggttcc aagtggagcc
    85321 aaatcgttac tataatggga ttggttcaga taagacatcg actttttatg aaaattggga
    85381 gcgggatatt gagcttttgt tagagactgg tcacacagtc tttcggactt ctattcagtg
    85441 gtcacggatt tttccacaag gctgtggaaa agtcaaccct caaggtgtgg atttttatcg
    85501 taaggtcttt gaggctatta aggctaaagg aattcgtctg ttagtcaatc tctatcattt
    85561 tgatttacct tttgcccttc aagaggatgg tgatggttgg gaaaataagg cgacagtctc
    85621 agcctatgaa gactatgctc gtttttgttt tgagacttat ggagatttag tggatcaatg
    85681 gattaccttt aacgagccca tcgttcctgt agaatttggt tatttttatg atgcccatta
    85741 tccacataag gtggatgcag aggcagctgt taaggtagcc tatcatacac aattggccag
    85801 cagccgggct gttaaggctt gccatgaact tttgcctgat tccaagattg ggattgtcct
    85861 caacttgaca ccggcttatc cacgtagcca gcatcctgct gatgtcaagg cagctcgtat
    85921 tgcggccctt tttcaggccc aatctttctt agatccatct gtcttgggga cttatccaca
    85981 ggagttggta gaaatcttgc atgaacacgg tcttttacct gatgctacag aggaagagtt
    86041 ggaactcatt cgtgataata cggtggactt ccttggtgtg aactactatc aacctttgcg
    86101 tgttatggct cctcgatttg ctaagcatcc agatagtcca ctcttaccag aacattttta
    86161 cgagccttat gtgatgcctg gacgtaaaat caattctcac cgtggttggg agatttatga
    86221 gcaagggatt tatgacatcg cccaaaatat caaggaaaat tatggcaata ttgagtggat
    86281 gttgactgag aatggtatgg gtgttgaagg ggaagaaaaa ttccgtcaag atggaatgat
    86341 tcaagatgat taccgtattg actttgtaaa aggtcatctt cgtgaacttc accgtgccat
    86401 tgaagatggt gccaactgta agggctactt gatttggacc tttattgact gctggtcatg
    86461 gctcaacagc tataaaaatc gctatggttt ggtcgaatta gacttggaaa cgcaagaacg
    86521 tcgtctgaag aaatcaggcc actggttcaa agaattaagc gataataatg gattttaaaa
    86581 aggactctga ctgattatcc caatcggtca gagttttttg cttacaggag cttaatttga
    86641 actataccaa tttttactct tgacaagtga aagaaacaag tatatactgt ttttgctgat
    86701 tctataaaag atgaattaga ctataccaat tttaaggaga aagcacagct tgcctgtgtc
    86761 gtatatacta tgtgtggaat tgttggtgtt gttggaaaca caaatgcaac tgatattttg
    86821 attcaagggc ttgaaaagct tgaataccgt ggctatgatt ctgcgggaat ttttgtccta
    86881 gatggtgctg ataaccattt ggtgaaggct gttggtcgta tcgcagaatt gtctgccaag
    86941 acagctggtg ttgagggaac aactggtatc ggacatactc gttgggcaac tcatgggaaa
    87001 ccaacggaag acaatgctca cccacaccgc tctgagacag aacgttttgt cttggttcac
    87061 aatggggtga ttgaaaacta ccttgaaatt aaagaagaat accttgctgg gcaccacttc
    87121 aaagggcaaa cagatacgga aatcgccgta catttgattg gaaaatttgc ggaagaagac
    87181 ggtctctcag ttcttgaagc ctttaaaaaa gctcttcata ttatccgtgg ttcatatgcc
    87241 tttgccttga ttgactctga aaatccagat gtcatctatg tagcgaaaaa caaatctcca
    87301 cttttgattg gtcttgggga aggctacaat atggtctgct cagatgctat ggctatgatt
    87361 cgtgaaacca accaatacat ggaaattcat gaccaagagt tggtaatcgt caaggctgat
    87421 agcgtggaag ttcaagacta tgatggtaac agtcgtgaac gtgctagcta tactgcggaa
    87481 cttgacttgt cagatatcgg taagggaact tatccttact acatgcttaa ggaaattgat
    87541 gagcaaccaa ctgttatgcg taaactcatt caagcctaca cggatgatgc tggtcaagta
    87601 gtgattgatc ctgctatcat taaggctgtt caagacgcag accgcatcta catccttgca
    87661 gctggaacat cttaccatgc aggatttgct tctaagaaaa tgttggaaga attgacagat
    87721 acaccagttg aacttggcat ctcatctgag tggggctacg gtatgccact tctcagcaag
    87781 aaaccactct tcatctttat cagccaatct ggtgaaacag cggatagtcg tcaagttttg
    87841 gtcaaggcta atgaaatggg aattccaagc ttaacagtga caaacgttcc aggttcaacc
    87901 ctctcacgtg aagccaacta taccatgctc cttcacgcag gtcctgaaat tgccgtggca
    87961 tcaactaaag cctatacagc gcaaatcgca gcccttgcct tccttgcaaa agcagtcgga
    88021 gaagcaaatg gtaatgctaa agcgcaagcc tttgacctgg ttcatgaatt gtcaatcgta
    88081 gctcagtcta tcgaatcaac tctttcagag aaagaaacca ttgaagccaa ggttcgtgaa
    88141 cttcttgaaa caactcgtaa cgccttttac atcggacgtg gtcaagatta ctacgtagcc
    88201 atggaagcaa gtctcaaact caaagagatt tcttatatcc agtgtgaagg ttttgcggca
    88261 ggagaactca agcacggaac cattgccttg attgaagaag gaacacctgt cttggctctc
    88321 ttgtcagatc cagtccttgc caaccacact cgtggaaata tccaagaggt ggcagcccgt
    88381 ggtgctaagg tcctcactat cgcagaagaa aatgttgcta aagataccga cgatatcgtc
    88441 cttacgactg tacaccctta cctctcacca atttcaatgg tcgtaccgac gcaattggtt
    88501 gcttactttg caaccctcca ccgtggcctc gatgtggata aaccacgtaa ccttgctaaa
    88561 tcagtaacgg tagaataagc taaaaaagtc tagttatcta ggctttttct aatgagcaaa
    88621 ttggttgctt gtactcaaga ttcgtgttag aataattttt caaattgaag gacagagata
    88681 gacaaggaga atcacaatgg tagaattggg aatttcaaca tttggggaaa taacggagct
    88741 tgaagggact ggacaaactt acagtcatgc tgaacgcatt cgccagttgg tggcagagat
    88801 tgagctggct gacaaggttg gtttggacgt atatgggatt ggcgagcacc atcgggcgga
    88861 ttttgcagta tcagccccag agattgtcct ggccgctggg gcagtcaata ccaagaaaat
    88921 ccgtttgacc agtgcagtca gcattctgtc aagcatggat ccgattcgtt tgttccaaca
    88981 gtatgccact atcgatgctt tgtcaaatgg acgatcggag attatggctg gaaggggctc
    89041 tttcacggaa tctttccctc tgtttggtta tgacttgaaa gactacgact ctctttttga
    89101 tgagaaatta gacttgcttc agttagtcaa tgaaaagacc aagttagact ggcaaggtcg
    89161 attgactcaa acgattgctg gtaaagaagt ttatcctcgt ccagttcagg acaaattgcc
    89221 cttgtggata gctacaggtg gtcatgtcga atcaacagtg aagattgctc aggctggtct
    89281 accgattgta tatgctatta ttggtggtaa tccacgttat tttaaaaagt tgattcaggc
    89341 ttatcgtgag attggaagcg aagcgggcca tgctgacaaa gacttgaaag tgggagccca
    89401 ttcttggggg tggattgcgg aagatggtga gcaggcggtg aaagattatt tccatccgac
    89461 taagcaagtg gtggatgcta tttccaaaga ccgtccgcac tggcaggaat tgcgttatga
    89521 gcaatatttg gagcaggtag ggccaaatgg cgccatgttt gttggcaatc caaatcaggt
    89581 ggccgaaaaa ttgattcgca tgatagagga tttaggattg gaccgcttca tgcttcatct
    89641 accgcttggt tctatgcctc atgaccaggt tctgagagct attgaactct tcggaacaca
    89701 agttgcaccc aaagtacgag cttattttgc tatgaaagag gcttaataaa aaatcctaat
    89761 caagtttatt aggacaacaa atattgtaca aaaattaatc ccccgagcta taatgcttgg
    89821 gggatttttc tataggaggg ctagtttagt tctctttttt attttttagt aagaaaccga
    89881 gaccaaggag cgcaaggagg ctgattcctg caaataggag tttgttttcg tttttgattc
    89941 ctgtatttgg aagttcagct tgtttatctg gggttgcagg tatattttcc ttgctagagt
    90001 tttctaccga ttcgtttcga accgcttctt ttacagatgc ttcttgtgct tcttgtgctg
    90061 gttgttcagc ttgtgaatca gctgtagctt ggctaggttt attttccgca tcagctactt
    90121 tggcatctgg tttagtagaa tcaggtctag cttctggagc tgggtcttga tgtgcagggt
    90181 gagaagcttc attttgatgt tcaggcttgg aaggggttga gtctggtttc tcttctgcag
    90241 ttgactcatg gctagttcca ttttgagaga ctcgaagaac agtagctgta agggcattca
    90301 atttcaagcc tttttcagtc cattcaagtc ctttcgggtt ggcaattccg actgatcctg
    90361 cttggttttc atctgccaaa acttccgcat ttcttagatg tgcaaaggca gttcccaaat
    90421 taaattcgcg agctttttca tccgcattga caaagactgc gtagatatca ccgtttggag
    90481 cagtgatttg gtagccaatc actacatcct ctttttccac accattttgg cctgggacag
    90541 tgatgaggtg gacacggtct ttgatatctt gaagactctt aagtcggaag gcatctgtag
    90601 attgacgaag ggcaatcaaa cctttcatat agtcacggct cttgacattt tcaggataag
    90661 ctttaccatc tgtagcctta gtccagtcaa acttgttgac tgcgtcgcta gaatcgtaag
    90721 aatcatggat gaagtaagga tagtcaaatg ggttgccgtc cttatcacgc aacaagtgag
    90781 atttgtttgg aaccttatcc tctgctactg gagtcttgta ggctgggtca cggaattgtt
    90841 tagtacgtcc atattcctga ccggagtgga taaatggagt tccttgagct gtcaagacca
    90901 tgagatttcc aagtcgtaaa cgacggtgga tttcagcata gttctcagcc ttgcttgggt
    90961 cttttttgat agactgggca atgatgtcaa agagggtcaa gttatcatgg gctgcgatgt
    91021 attggatgac atctccaggg ctgtcagctt caaagttagt tggttgagca atgagatttt
    91081 taaagatggt gttgacatca cgcttgccac ctgtgataaa ggcaggttga ccttcgtttg
    91141 gataaccaga tttgaggttg ttacggatgt catctgaaaa gacagcgaca gtatcggtat
    91201 gtttcatcca atcttggtca gcagccttag taggcatgtt ttcatcaccg gcataggttc
    91261 tccaaccttc accaagcatg atgaggtttg gattgagggc gcgtgcagcc ttgtaagctt
    91321 cttcgataga agcggcgtca tggtctccca tcatatcgaa gcggaagcca tccactttgt
    91381 aggtatcaac taggtatttg atagagtcaa ctaggagccg tttggtcata tggtgggttg
    91441 tccccaagcg tccaccacca aagctagttc gaggtgtgcc atcggcatcc ataaagtggt
    91501 agtagtttgg ctctaggtct tcaaagatat cgactttggc tgtgtggtta taaacgacat
    91561 ctaggatagc tcccatacca cgtttgtgga tttcgttgat gaggttttta aattctgcga
    91621 ttcgtttttc tggattctta ggatcgcttg agtacatacc agtcaaggag aagtagtttt
    91681 gagggtcata tccccagttg tagttgctgt tgcttgaagc gtagtcagac aagcgttcat
    91741 ggtttttcaa ttcattgaca aagtagtaag acaagactgg aaggagctgg atatgggtta
    91801 cacccaagtc tttgagatag tctagttttt caatgaaggc ttcaaaagtc ccaaatggtt
    91861 tggtcaagtc ttttgcaatg gcaggatctg aagtgaagtc acgcacatga gcttcgtaga
    91921 taacggcgtc ttcacgagtc ttgaaattgt gaatcttacc ataagtcaag tcttgaggtc
    91981 cgagtttagc tggatctaca aaggcggctt tagccacttt atgggcatcg tcaattttgg
    92041 catcgtcgct attccaagca gcaagagatt tagcgtaagg atcgagtgca agaacagttt
    92101 taccttgacg ctcgatttgg tattgataat agtagccagt gaaatctgtg attccgagtt
    92161 tgtttgtgct gtctagagtt tgtttccaag ttcctctttc ccctttttcg agagcgacag
    92221 ttccaactac tttgtcaggg tcattcttgt cgtagacaac aacagaaacc ttatcagcac
    92281 ttggtgacca aagggtcaaa tcaacttgtt ttccttcttc ttttaggtca gctcccagtt
    92341 tgccatcata gctgtatgtc tcatctttca ggcgccagct tgttttggta gtgaattggt
    92401 cggaattgta gctaacagta taaggatgtt ttgtgtcaga gaaatctccg ctgtaggtca
    92461 ctttcttacc agcttcatcg attgcaacat cggtaatagt taccttgttt cctaggtgat
    92521 tagtgatgtt ggagtgtttg aggatatctt cttttttagc accgacaagt gttgaaaagc
    92581 tactttcaat gctagaagtg cctacgtgtt gggctcctgt catacggata tcatggacat
    92641 agtatggatt tgtgtaaatc gattcatcat cgtcttttag gaaaatttgg ctatgatttt
    92701 tcaaatctgt gaacttataa ttttctttac ggattttcac gtcgtctcct tgtttgctct
    92761 catctagtaa taaaaatcca aattctcttg cggcttcatt aagaggaatg tcgatatagc
    92821 ggccatattt gcctgtagcc gtaaagtctg ttccgtcagg ccattgagcg ctacttggat
    92881 tttttacatc tccccagtac cagagagatt tcttgtcata gttgccatct gtgcggtagt
    92941 agttgacgcg aacagttcct gcaggctgtg gctcgtaaga gaaaaccttg taatcttggt
    93001 ctaaccaagc ctcgttcatt tttggaacta gtttttctac agatttatcg ccggttagat
    93061 tttttccagc tgtattgttg atgaggaagc taattttctt ggcttgttct ccctttaatt
    93121 tgacatctag gtaatagccg tagtcatctt tcttggcatc cttgaaggac aaagctccgt
    93181 ttggccagtt ttcagatggt ttttcaacat cgtcccaagt ccatagtcct tgagcatcct
    93241 tgttttcttc aggaagtttt ttgacatgga tacggaagta gttatcttcg atgggctctt
    93301 ctgccttagt ttcagttgtt actggactag tagaagtagt tggctctgtt gcaggttttt
    93361 cttctgtttt ctctagggaa gcgtttgcat ttctaggtga agaaatatca ctttcgttct
    93421 taccagagcc agctgctgta tcagtaagag gttgggcaag ggtggttgta tttctgttgt
    93481 tgggttcgtt agtggttggt gtactttcgt cggatgagat agttggtgta gccatggcaa
    93541 gcaagacaag gcttgcgccg ataaggacag aaccagttcc atttttgagg gaacggatgc
    93601 tgtagaccat ttttttctca gtgtgagatg gtgtttttct cataatgatt ctccaatcaa
    93661 taaatttcta tatcagtata gcatgtagta aaacaatatg caagcgtttt ctttgatttg
    93721 tgaaaaaaat tcttactttt gagaagtttt ctgtactatt ttatatatca gtataaatga
    93781 cggagataaa aatgtcacat aagccaagcc gtattattag gaagatgatg tgttcccagc
    93841 tatttttatt cagaaattga tctctaacat taccaataaa aaagaaaaat atcttgacaa
    93901 gcaagggaaa attttgttac aataatagac ggtacttttt acttttggtc tctcaagagt
    93961 gtacagggac gtgctgacaa atgttgcaaa agtacacaca gatgatagct gtcaccaagt
    94021 gtatcatcac caaaaataaa aaaacacagg agaatgtaga tgcctacaat taaccaattg
    94081 gttcgcaaac cgcgtaaatc aaaagtagaa aaatctaaat caccagcttt gaacgttggt
    94141 tacaacagtc ataaaaaagt tcaaacaaac gtttcttcac cacaaaaacg tggtgttgca
    94201 actcgtgttg gaacaatgac acctagaaaa cctaactcag cccttcgtaa attcgctcgt
    94261 gtacgtttga gcaaccttat cgaagttact gcctacatcc caggtatcgg acacaacttg
    94321 caagagcaca gcgtggtgct tcttcgtggt ggacatgtaa aagaccttcc aggggtacgt
    94381 taccatatcg tccgtggtgc acttgatact gcaggtgtta acgatcgtaa acaaggccgt
    94441 tctaaatacg gtactaaacg tccaaaagca taaggaaagg ggataaagag aaatgagtcg
    94501 taaaaataga gctccaaaac gtgacgtatt gccagatccg ctttacaatt cacaactagt
    94561 tactcgtctt atcaaccgcg ttatgcttga tggtaaacgt ggtacagctg cttcaatcgt
    94621 ttacggtgcc tttgagcaaa tcaaagaagc tactggaaac gatgcacttg aagtatttga
    94681 aacagctatg gaaaacatca tgcctgtact tgaagtacgt gcacgtcgtg ttggtggttc
    94741 taactaccaa gtcccagttg aagttcgtcc agaacgtcgt acaacacttg gacttcgttg
    94801 gttggtaaca atcgctcgtc ttcgtggtga acacacaatg caagaccgtc ttgcaaaaga
    94861 aatcttggat gctgctaaca acactggtgc agctgttaag aaacgtgaag acactcaccg
    94921 tatggctgaa gctaaccgtg cattcgcaca cttccgttgg taatatagga tgcgaaagcg
    94981 ttaagaaagt cccagagaaa atagggaatc aaagcaggtt gagattgcaa ccaatgagat
    95041 tcatcttttt ctccagactt ttagcttgag ctcaactata tcatgatgct aggaacggta
    95101 aggatgcaag gtgaaaatag gaaactgacg cagtattcga tgaatacaag gaagtttatc
    95161 tttttcacac agcatcccgt tccagctcaa atcggctaac taactttagt ccgagttcga
    95221 ttcaatttgt aaacctacaa gttgaaacca acaatagcat gaaaacattg agaacgggta
    95281 ggtcctgcct atccgttttt attaaaatcg tgttataata gaatagaaat caaaaataaa
    95341 taggagaaac aaacctcatg gcacgcgaat tttcacttga aaaaactcgt aatatcggta
    95401 tcatggctca cgtcgatgct ggtaaaacaa caactactga gcgtattctt tactacactg
    95461 gtaaaatcca caaaatcggt gaaactcacg aaggtgcgtc acaaatggac tggatggagc
    95521 aagagcaaga gcgtggtatc actatcacat ctgctgcgac aacagctcaa tggaacaatc
    95581 accgcgtaaa catcatcgac acaccaggac acgtggactt cacaatcgaa gtacaacgtt
    95641 ctcttcgtgt attggatggt gcggttaccg ttcttgactc acaatcaggt gttgagcctc
    95701 aaactgaaac agtttggcgt caagcaactg agtatggagt tccacgtatc gtatttgcca
    95761 acaaaatgga caaaatcggt gctgacttcc tttactctgt aagcacactt cacgatcgtc
    95821 ttcaagcaaa tgcccaccca atccaattgc caatcggttc tgaagatgac ttccgtggta
    95881 tcatcgactt gatcaagatg aaagctgaaa tctatacgaa cgaccttggt acagatatcc
    95941 ttgaagaaga tattccagct gaataccttg accaagctca agaataccgt gaaaaattgg
    96001 ttgaagcagt tgctgaaact gacgaagaat tgatgatgaa atacctcgaa ggtgaagaaa
    96061 tcactaacga agaattgaaa gctggtatcc gtaaagcgac tatcaacgtt gaattcttcc
    96121 cagtattgtg tggttctgcc ttcaagaaca aaggtgttca attgatgctt gatgcagtta
    96181 ttgactacct tccaagccca cttgatatcc cagctatcaa aggtattaac ccagatacag
    96241 acgaagaaga aactcgtcca gcatctgacg aagagccatt tgcagctctt gccttcaaga
    96301 tcatgactga cccattcgta ggtcgtttga cattcttccg tgtttactca ggtgttcttc
    96361 aatcaggttc atacgtattg aacacttcta aaggtaaacg tgaacgtatc ggacgtatcc
    96421 ttcaaatgca cgctaacagc cgtcaagaaa tcgacactgt ttactcaggt gatatcgctg
    96481 ctgccgttgg tttgaaagat actacaactg gtgactcatt gacagatgaa aaagctaaaa
    96541 tcatccttga gtcaatcaac gttccagaac cagttatcca attgatggtt gagccaaaat
    96601 ctaaagctga ccaagacaag atgggtatcg cccttcaaaa attggctgaa gaagatccaa
    96661 cattccgcgt tgaaacaaac gttgaaactg gtgaaacagt tatctctggt atgggtgagc
    96721 ttcaccttga tgtccttgtt gaccgtatgc gtcgtgagtt caaagttgaa gcaaacgtag
    96781 gtgcgcctca agtatcttac cgtgaaacat tccgcgcttc tactcaagca cgtggattct
    96841 tcaaacgtca gtctggtggt aaaggtcaat tcggtgatgt atggattgaa tttactccaa
    96901 acgaagaagg taaaggattc gaattcgaaa acgcaatcgt cggtggtgtg gttcctcgcg
    96961 aatttatccc agcggttgaa aaaggtttgg tagaatctat ggctaacggt gttcttgcag
    97021 gttacccaat ggttgacgtt aaagctaagc tttacgatgg ttcataccac gatgtcgact
    97081 catctgaaac tgccttcaag atcgcggctt cacttgctct taaagaagct gctaaatcag
    97141 cacaaccagc tatccttgag ccaatgatgc ttgtaacaat cactgttcca gaagaaaacc
    97201 ttggtgatgt tatgggtcac gtaactgctc gtcgtggacg tgtagatggt atggaagcac
    97261 atggtaacag ccaaatcgtt cgtgcttacg ttccacttgc tgaaatgttc ggttacgcaa
    97321 cagttcttcg ttctgcatct caaggacgtg gtacattcat gatggtattt gaccactacg
    97381 aagatgtacc taagtcagta caagaagaaa tcattaagaa aaacaaaggt gaagactaat
    97441 cagtcctcac tctagaagga agtcacttag tggcttcctt ttgtctttag aaaacacctc
    97501 taagtatggt aaaatagtag gagaataatg tgaggaaaat gaatgtcaaa tagttttgaa
    97561 attttgatga atcaattggg gatgcctgct gaaatgagac aggctcctgc tttagcacag
    97621 gccgatattg agcgagttgt ggttcataaa attagtaagg tatgggagtt tcatttcgta
    97681 ttttctaata ttttaccgat tgaaatcttt ttagaattaa agaagggttt gagggaagaa
    97741 ttttctaaga cagggaataa agctattttc gaaatcaagg ttctgtctca agaattttca
    97801 aatcaactct tacaagccta ttatagagag gttttttctg aagggccgtg tgctagtcaa
    97861 ggctttaaat ctctttatca gaatttgcaa gttcgtgcgg aggacaatca actctttatt
    97921 gaaggctcag aggcgattga taaggaacac tttaagaaaa atcatctgcc taatttagct
    97981 aaacaacttg aaaaatttgg ttttccagct tttaactgtc aggtcgagaa gaatgatgtg
    98041 ctgacccaag agcaggaaga ggccttttat gctgaaaatg agcagattgt tcaagctgcc
    98101 aacgaggaag cgctccgtgc tatggagcaa ctggaacaga tggcacctcc tccagcggaa
    98161 gagaaaccag cctttgattt tcaggccaaa aaagctgaag ctaaaccaaa gctggacaag
    98221 gcggagatta ctcctatgat cgaagtgacg acggaggaaa atcgtctggt ctttgaaggg
    98281 gttgtttttg atgtggagca aaaagtgacc agaacagggc gtgttttgat caactttaaa
    98341 atgacggact acacttcaag tttttcgatg caaaagtggg ttaagaacga ggaagaggct
    98401 cagaagtttg atttaatcaa gaaaaactct tggcttcgag tccgtgggaa tgtggagatg
    98461 aataacttca cacgcgattt gactatgaat gtgcaggatg tgcaggaagt tgttcactat
    98521 gagcggaagg atttgatgcc agaaggtgag cgccgggttg agtttcatgc tcatactaat
    98581 atgtcgacca tggatgctct accagaggta gaagaaatcg ttgcaacagc tgctaagtgg
    98641 ggacacaagg cggttgccat cacggaccat gggaatgtcc agtccttccc acatggctat
    98701 aaggcggcta agaaagcggg aatccagctg atctatggta tggaagctaa tatcgtggag
    98761 gaccgtgtcc ctatcgtcta taacgaagta gagatggact tgttagaagc gacctacgtg
    98821 gtctttgacg tggaaacgac ggggctttca gccatctata atgacttgat tcaggttgcg
    98881 gcttctaaga tgtacaaggg gaatgttatt gccgaatttg atgaatttat caatcctggg
    98941 catcccttgt cagcttttac tactgagttg accggaatta cagatgatca tgtaaaaaat
    99001 gctaaaccac tagaacaagt tttgcaagaa ttccaagaat tctgcaagga tactgtccta
    99061 gtcgcccaca atgcgacctt tgacgttggc tttatgaatg ccaattatga gcgtcatggt
    99121 ctgccaaaga ttagtcagcc agttattgat acacttgagt ttgctagaaa tctctatcct
    99181 gagtataaac gtcatggttt ggggcctttg accaagcgtt ttggtgtggc cttagaacat
    99241 caccacatgg ccaactacga tgcggaagct acaggtcgcc tgcttttcat ctttatcaaa
    99301 gaggtggcag aaaaacatgg tgtgaccgat ctagctagac tcaacattga tttgattagt
    99361 ccagattctt ataaaaaagc tcgcatcaag catgcgacca tttatgtcaa gaatcaagta
    99421 gggctaaaaa atatctttaa gctggtttcc ttgtctaata ccaagtactt tgaaggagtg
    99481 ccacggattc caagaacggt tctagatgct catcgggaag gtttgatttt aggttcagct
    99541 tgctctgaag gtgaagtttt tgatgcagtc gtttcccagg gcgtggatgc ggcggttgag
    99601 gtggccaagt attatgactt tatcgaggtc atgcccccag ctatctatgc tcccttgatt
    99661 gccaaggagc aggtcaagga tatggaggaa ctccagacca ttatcaagag tttgatagaa
    99721 gttggagacc gtcttggtaa acccgttctg gctaccggaa atgttcacta tatcgaaccg
    99781 gaagaagaga tttaccgtga aattatcgtc cgtagtttgg gacagggggc gatgattaac
    99841 cgaactattg gtcatggcga acatgcccaa cccgctcctc ttccaaaagc tcattttaga
    99901 acgactaatg aaatgttgga tgaatttgcc ttcttgggag aggaattagc tcgcaaattg
    99961 gttattgaaa ataccaatgc cttggcagat atctttgaac ctgttgaggt agttaagggt
   100021 gacttgtata cgcctttcat cgacaaggcg gaagaaacgg tcgctgaatt gacctataag
   100081 aaggcctttg agatttatgg taatccgctg ccagatatcg ttgatttgcg gattgaaaaa
   100141 gaactaacct ctattctggg gaatggattt gctgtgattt atctggcctc gcagatgctg
   100201 gttcaacgtt ccaatgaacg gggctacttg gttggttctc gtgggtctgt cggatctagt
   100261 ttcgttgcga ccatgattgg gattacagag gtcaatcctc tctctcctca ctatgtctgt
   100321 ggtcagtgtc agtacagcga gtttatcacc gatggttctt atggttcagg ttttgatatg
   100381 cccaataagg actgtccaaa ctgtggtcat aaactcagca aaaacggaca ggatattcct
   100441 ttcgagacct tccttggttt tgatggggat aaggttcctg atattgactt gaacttctcg
   100501 ggagaagatc agcctagcgc ccacttggat gtgcgtgata tctttggtga agaatatgcc
   100561 ttccgtgcag gaacggttgg tacggtagct gctaaaactg cttatggctt tgtaaagggc
   100621 tatgagcgag attatggcaa gttttatcgt gatgcagagg tggaacgtct tgctcaaggt
   100681 gcggctggtg tcaagcggac aacgggacaa cacccggggg gaatcgttgt tattcctaac
   100741 tacatggatg tttacgattt tacgcctgtc cagtatccag cagatgacgt gacggctgaa
   100801 tggcagacca ctcactttaa ctttcacgat atcgatgaga acgttctcaa actcgatgtg
   100861 ctggggcatg atgatccgac catgattcgg aaactgcagg atttgtctgg gattgatcct
   100921 aatgaaatcc ctatggatga tgaaggtgtg atggctctct tttctgggac tgacgtgctt
   100981 ggggtaacac ctgaacaaat cggaacgcca acgggcatgc tgggaattcc agagtttgga
   101041 accaactttg tacgtgggat ggtagatgag acgcatccga cgacctttgc ggagttgctt
   101101 cagctgtctg gattatccca tggtaccgat gtctggttgg gaaatgctca ggatttaatc
   101161 aagcaaggga ttgcggatct atcgaccgtt atcggttgtc gggacgacat catggtttac
   101221 ctcatgcatg ctggtctaga acctaagatg gcctttacta tcatggaacg ggtacgtaag
   101281 ggcttgtggt tgaagatttc agaagaggaa cgaaatggct atatcgaagc catgaaagct
   101341 aacaaggtgc cagagtggta tatcgaatcc tgtgggaaaa tcaagtatat gttccctaaa
   101401 gcccatgcgg cagcctacgt tatgatggcc ttgcgtgtgg cctacttcaa ggttcaccat
   101461 cccatttatt actactgtgc ttacttctca atccgcgcca aggcttttga tatcaagacc
   101521 atgggagcag gcttggatgc tattaagcgt agaatggaag aaatctctga aaaacggaag
   101581 aacaatgaag cctctaatgt ggaaattgac ctctatacaa cccttgagat tgtcaatgaa
   101641 atgtgggaac gcggtttcaa gtttgggaag ttagacctct accgtagtga tgcgactgaa
   101701 ttcatcattg acggagatac gctgattcca ccatttgtag caatggatgg tctgggagag
   101761 aacgttgcca agcaattggt gcgagcgcga gaagagggag aatttctctc taaaacagaa
   101821 ctacgcaagc gtggtggact ctcatcaacc ttggttgaaa agatggatga aatggggatt
   101881 ctgggcaata tgccagagga caatcagttg agtttgtttg atgagttgtt ttaaaaaatt
   101941 gtgactcttt gtcaactgta gtgggttgaa aaaaagctaa gctcgagaaa ggacaaattt
   102001 cgtcctttct tttttgatat tcagggcgat aaaaatccgt tttttgaagt tttcaaagtt
   102061 ccgaaaacca aaggcattgc gcttgataag tttgatgaga ttattggtcg cttccaattt
   102121 ggcgttagaa tagtgtagtt gaagggcgtt gacgattttc tctttgtcct ttagaaaggt
   102181 tttaaagaca gtctgaaaaa gaggatgaac ctgctttaga ttgtcctcaa tgagtccgaa
   102241 aaatttctcc ggttccttat tctgaaagtg aaacagcaag agttgataga gctgatagtg
   102301 atgtttcaag tcttgtgaat agctcaaaag cttgtttaaa atctctttat tggttaagtg
   102361 catacgaaaa gtaggacgat aaaaatgttt atcgctgagt ttacgactat cctgttgtat
   102421 gagcttccag tagcgcttga tagccttgta ttcatgagac tttcgatcca attgattcat
   102481 gatttgaaca cgcacacgac tcatagcacg gctaagatgt tgtacaatgt gaaagcgatc
   102541 caacacgatt ttagcacatg ggaaaagttg tctagctaag tcatagtaag gactaaacat
   102601 atccatagta ataattttga cgcgacatcg gacggctcta tcatatttaa gaaagtgatt
   102661 tcgaatgata gcttgtgttc ttccctcaag aacagtgatg atattgagat tgttaaaatc
   102721 ttgcgcaatg aagctcatct ttccctttgt aaaagcatac tcatcccaag acataatctc
   102781 aggaagacaa gaaaaatcat gtttaaagtg aaa
//
LOCUS       DAVHTH010000002        71134 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.002, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000002 DAVHTH010000000
VERSION     DAVHTH010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 71134)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 71134)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..71134
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.002"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            complement(<1..463)
                     /locus_tag="VVR63_000109"
     CDS             complement(<1..463)
                     /locus_tag="VVR63_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001111259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6128176.1"
                     /translation="MPANTKVIFQEMFADFQNYYVLIGGTATSIVLDSQGFKSRTTKD
                     YDMVIIDEVKNKEFYTTLNHFLELGEYQGSQKDEKAQLFRFTTTNPEFHSMIELFSIL
                     PEYPLKKDGREIPLYFDQDASLSALLLDEDYYNILVHEKETIQGYSVLSNCG"
     gene            complement(453..650)
                     /locus_tag="VVR63_000110"
     CDS             complement(453..650)
                     /locus_tag="VVR63_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6128177.1"
                     /translation="MLEIWKYRPFVSEFWNDFKNNHDKQFVDSISLYLTLKDDDDPRI
                     EEESEALENMILQYLGEDDAS"
     gene            complement(654..1448)
                     /locus_tag="VVR63_000111"
     CDS             complement(654..1448)
                     /locus_tag="VVR63_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6128178.1"
                     /translation="MNVKKIMSIFQSFYVDVSIEELTLTLPISFVKRFEYTQMTFHKE
                     SFLLIKEKRRGSLSSFVTQARTMGEKANMDVVLVFSKLSDSEKKQLLQARVPFVDFKG
                     NLFFPPLGLVLNANDTEIPKELTPSEQLTWIAFLLTKGQKVVNVDLLSQVTGLPNSTI
                     YRCLRTFKALYWLNKQNKLYTYTVSKKELFLKSVSCLFNPIKKRILLPDGDIKQIKSV
                     SNLLYGGAYALSHSTFLAETDENTSYVIWQRKFNQLSLPLSQHVLK"
     gene            complement(1856..2281)
                     /locus_tag="VVR63_000112"
     CDS             complement(1856..2281)
                     /locus_tag="VVR63_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000204059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6128179.1"
                     /translation="MTSRVFIDADCISVFLWVGTEHLLEKLYLGKIVIPQEVYDEINI
                     PTIPHLKSRIDQLVTKGSAEIVSIDIGTEEYALYRDLTRNHDSNKIIGKGEATSIFLA
                     KKHNGILGSNNLRDVKPYVEEFSLEHMTTGDILIEAFKA"
     gene            complement(2410..2793)
                     /locus_tag="VVR63_000113"
     CDS             complement(2410..2793)
                     /locus_tag="VVR63_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6128180.1"
                     /translation="MYHLYYDEVKKSSVSLILIGEGDETERKADQFASYFLIFPSSLY
                     RMVEEIRENANRTHLEVEDIIKLGQFYGISHKAMLYRLRNDGYLDAEEIKNMDISVIE
                     TASRLGYDTSLYRPLSESKKEMASG"
     gene            complement(2815..3021)
                     /locus_tag="VVR63_000114"
     CDS             complement(2815..3021)
                     /locus_tag="VVR63_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6128181.1"
                     /translation="MDLSNKASNLRKKLGADGESPIDIFKLVQKIENLTLVFYGLGKN
                     ISGVCYKGTQFSLIAVNSDMPLGR"
     gene            complement(3008..3169)
                     /locus_tag="VVR63_000115"
     CDS             complement(3008..3169)
                     /locus_tag="VVR63_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU6128182.1"
                     /translation="MYVINVCDVGKRIKELRISSNLTQDKIAEYLSLNQSMIAKMEKG
                     ERNITNGFK"
     gene            complement(3528..4484)
                     /gene="lytA"
                     /locus_tag="VVR63_000116"
     CDS             complement(3528..4484)
                     /gene="lytA"
                     /locus_tag="VVR63_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HEU6128183.1"
                     /translation="MEINVSKLRTDLPQVGVQPYRQVHAHSTGNPHSTVQNEADYHWR
                     KDPELGFFSHIVGNGCIMQVGPVDNGAWDVGGGWNAETYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKYDIENGLTIETGWQKNDTGYWYVHSDGSYPKDKFEKINGTWYYFDSSGYMLAD
                     RWRKHTDGNWYWFDNSGEMATGWKKIADKWYYFNEEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPEFTVEPDGLITVK"
     gene            complement(4860..6230)
                     /locus_tag="VVR63_000117"
     CDS             complement(4860..6230)
                     /locus_tag="VVR63_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEU6128184.1"
                     /translation="MNKKRTVDLIHGPILPSLLSFTFPILLSNIFQQLYNTADVLIVG
                     RFLGQESLAAVGATTAIFDLIVGFTLGVGNGMGIVIARYYGARNFTKIKEAVAATWIL
                     GALLSILVMLLGFLGLYPLLQYLDTPAEILPQSYQYISMIVTCVGVSFAYNLFAGLLR
                     SIGDSLAALGFLIFSALVNVVLDLYFITQLHLGVQSAGLATIISQGLSAVLCFYYIRK
                     SVPELLPQFKHFKWDKSLYADLLEQGLAMGLMSSIVSIGSVILQSSVNTFGAVIISAQ
                     TAARRIMTFALLPMTAISASMTTFASQSLGAKRPDRIAQGLRIGSRLSISWAVFVCIF
                     LFFASPALVSFLASSTDGYLIENGSLYLQISSAFYPILSLLLIYRNCLQGLGQKILPL
                     VSSFIELIGKIVFVVLIIPWAGYKGVILCEPLIWVAMTVQLYFSLFRHPLIKEGKAIL
                     ATKVQS"
     gene            complement(6537..7703)
                     /gene="recA"
                     /locus_tag="VVR63_000118"
     CDS             complement(6537..7703)
                     /gene="recA"
                     /locus_tag="VVR63_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HEU6128185.1"
                     /translation="MAKKPKKLEEISKKFGAEREKALNDALKLIEKDFGKGSIMRLGE
                     RAEQKVQVMSSGSLALDIALGSGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLGASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGNTQIKGTGDQKETNVGKETKIKVVKNKVAPPFKEAV
                     VEIMYGEGISKTGELLKIASDLDIIKKAGAWYSYKDEKIGQGSENAKKYLAEHPEIFD
                     EIDKQVRSKFGLIDGEEVSEQDTENKKDEPKKEEAVNEEVPLDLGDELEIEIEE"
     gene            complement(7758..9014)
                     /locus_tag="VVR63_000119"
     CDS             complement(7758..9014)
                     /locus_tag="VVR63_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HEU6128186.1"
                     /translation="MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGD
                     NEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQTLVKFLGKALVFDPQAQEKLDIF
                     FALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
                     VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLR
                     LSTKASSQEEANQALDILENQILDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQG
                     KTIAAAESLTAGLFQATVANFSGASSIFKGGFVTYSLEEKSRMLDIPAKNLEEHGVVS
                     EFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQEQGTEVIKVNIG
                     GRSRADVRHIAVMHAFNLVRKALLSD"
     gene            complement(9099..10115)
                     /locus_tag="VVR63_000120"
     CDS             complement(9099..10115)
                     /locus_tag="VVR63_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEU6128187.1"
                     /translation="MVKKIIGMVLALLSVTVVGVGVFAYTIYQQGTETLAKTYKKIGE
                     ETKVIEATEPLTILLMGVDTGNVERTETWVGRSDSMILMTVNPKTKKTTMMSLERDIL
                     TRIESGNGQAHEAKLNSAYADGGAELAIETIQKMMNIHIDRYVMVNMRGLQKLVDAVG
                     GITVNNILGFPISISDQEEFNTISIGVGEQHIGGEEALVYARMRYQDPEGDYGRQKRQ
                     REVIQKVMEKALSLNSVGHYQEILKALSDNMQTNIDLSAKSIPNLLGYKDSFKTIETQ
                     QLQGEGEILQGVSYQIVSRAHMLEMQNILRRSLGQEEVTQLETNAVLFEDLFGRAPVG
                     DEDN"
     gene            complement(10123..10641)
                     /locus_tag="VVR63_000121"
     CDS             complement(10123..10641)
                     /locus_tag="VVR63_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6128188.1"
                     /translation="MEYELLIREAEPKDAAELVAFLNRVSLETDFTSLDGDGILLTSE
                     EMEIFLNKQASSDNQITLLAFLNGKIAGIVNITADQRKRVRHIGDLFIVIGKRYWNNG
                     LGSLLLEEAIEWAQASGILRRLQLTVQTRNQAAVHLYQKHGFVIEGSQERGAYIEEGK
                     FIDVYLMGKLIG"
     gene            complement(10631..11074)
                     /gene="tsaE"
                     /locus_tag="VVR63_000122"
     CDS             complement(10631..11074)
                     /gene="tsaE"
                     /locus_tag="VVR63_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HEU6128189.1"
                     /translation="MYTKNEEELQALGERLGHLLAKNDVLILTGELGAGKTTFTKGLA
                     KGLQISQMIKSPTYTIVREYEGRLPLYHLDVYRIEGDADSIDLDEFIFGGGVTVIEWG
                     NLLGDALPDAYLELEILKEADGRRLNFQAKGLRAEKLLEELQYGV"
     gene            complement(11160..11780)
                     /locus_tag="VVR63_000123"
     CDS             complement(11160..11780)
                     /locus_tag="VVR63_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6128190.1"
                     /translation="MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFV
                     SGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLLINLLGAVLVLSDNLFIKNTLQQ
                     ELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
                     VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF"
     gene            complement(12163..13026)
                     /locus_tag="VVR63_000124"
     CDS             complement(12163..13026)
                     /locus_tag="VVR63_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU6128191.1"
                     /translation="MNTLAEKFRLKRKELRLSQQTLAEGICEQSQISKIERGHFIPSA
                     DLLFKLSQRLEVPLDYFFNEQIEVKSNLSNFKHLSARLLDDRNYDDLEYLYKIEVERS
                     TFLTLEDRTYLEWIKSIIDFYQYDSKCEAISSLENILLKVSSNTLIYLKALNTLSNFY
                     SLVGREQEYEANYSHLIELYQTKNLDHQEFLFGYIRVRYNYAHYLVSKEKYNEAIQEA
                     LETIELCKQRQTSYQLAPLLILVGNAGAKFLDREQVKNYYIEARELCKIYNNPLMLMK
                     IENYLKELDTV"
     gene            13492..13716
                     /gene="pneA1"
                     /locus_tag="VVR63_000125"
     CDS             13492..13716
                     /gene="pneA1"
                     /locus_tag="VVR63_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit PneA1"
                     /protein_id="HEU6128192.1"
                     /translation="MTNFNSNEKFCGKSLKSLSADEMSLIYGASDGAEPRWTPTPIIL
                     KSAAASSKVCISAAVSGIGGLVSYNNDCLG"
     gene            13723..13911
                     /gene="pneA2"
                     /locus_tag="VVR63_000126"
     CDS             13723..13911
                     /gene="pneA2"
                     /locus_tag="VVR63_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000786759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit PneA2"
                     /protein_id="HEU6128193.1"
                     /translation="MKNDFVIGKSLKELSLEEMQLVYGGTDGADPRSTIICSATLSFI
                     ASYLGSAQTRCGKDNKKK"
     gene            14027..17017
                     /gene="lanM"
                     /locus_tag="VVR63_000127"
     CDS             14027..17017
                     /gene="lanM"
                     /locus_tag="VVR63_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000875571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 lantipeptide synthetase LanM"
                     /protein_id="HEU6128194.1"
                     /translation="MKYKIKNVHKTLFIKERYQILSERNDNSLNNFSLNNWRSTMSII
                     SEKTFEEMLKLNNYNKKIFSNTVNYDYTEEQIRLYSEYAKNSEWYKFAEGSFEIFRKH
                     PQRINFKKDFSRILEPFIINLLKLINNYLENKEYEWIDKNGNIFSSLVFYLEDLIYPW
                     IVKPLVLEINSLREKGLLEGESEQQRYKYFITLFDKEENILNFYNKYPVLLRQISESC
                     LRFYTYFIEILSNLENDFSVLEEELGLRGKLNDIKFGKGDTHSQGKTVLILFFDDAKI
                     VYKPKNLIINNSLNTIAEYIRKVDEKIRIRIPRTIAYSDHSYEEFIDYLPLEQKKKLP
                     EYYYNFGVLLAFIYLFNGSDIHFENLISYGDMPVIIDFETMLQQPLFDDKTGQSLLDT
                     LFHRVTRTLLLPTEGVKREDGLDVEMSALTGNFKKDAFNGQVLINLNTDKVKFDIGKI
                     DFEGGKNLPVRDGDIEFDKYIKDFKKGFRDFYLIFEELNKTEEFKMLLKANLYGLKTR
                     VLFRDTNSYASVLSFLYHPDFYEEMLDREKALENLWSNKFSNQGIVASECEQMRLLDI
                     PIFYTDTNINEIYDDFGNHFISLHQFSGYDYFMKYLPNNNLENLEKQLDIIEIYFPSF
                     DQRKKGYKLNLSNRKKLPNESLVTILHNEVENIADSLVINNIYDEYPIWSIPVNFKGS
                     KWCLEQTGNDMYRGRAGILLFMYYVKLLKDKSSYTQLYNKMLSAIPPSVSLSKTTFGL
                     TGDIGYFIVLSIIEDYDTNTLACLNYIKSVLTELEKTDFASVSNKSDYINGLLPLINT
                     LVRYYRKGIEKERVLRLVLSLGDTLYNDVSERDNSNFGYSFGHGLSGVIFTLKNIYKV
                     TRLKKYKELILQLVPREKIKIHSLKWCSGEFGTLVNHPQSVPEGIVASLDNDTFCHGS
                     MAIINFYIDYMKEMDTSMELESLLCSVVMNKSKEGEYRIVQTSNFPDFSLYTGVTGIA
                     YTFLRYIALNQNDKKIVIPSLLEI"
     gene            17367..18071
                     /locus_tag="VVR63_000128"
     CDS             17367..18071
                     /locus_tag="VVR63_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001033172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HEU6128195.1"
                     /translation="MNKIFIYAGVRNHNSKTLEYTKRLSSIISSRNNVDISFRTPFNS
                     ELEISNSDSEELFKKGIDRQSNADDGGVIKKELLESDIIIISSPVYLQNVSVDTKNFI
                     ERIGGWSHLFRLAGKFVVTLDVAESNGSDNVSEYLRDIFSYMGGQILHQVSITNSLKD
                     IAEAQLMEATYKIEDVLEGKIKYKTTDYQERAYQTLKLILENYDSEHFEKMYWEKKRL
                     FEANSLEEWYYVENIK"
     gene            18052..18981
                     /locus_tag="VVR63_000129"
     CDS             18052..18981
                     /locus_tag="VVR63_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M50 family metallopeptidase"
                     /protein_id="HEU6128196.1"
                     /translation="MLKILNNSVIYLCLIPLLFLLLIIFPNDSLIYYFRLILISLISI
                     TLHELGHFLVGRCLSYKLEMLATPFFFYFRKKIYFKFPVLLAFGYCQMSNRNITNEKN
                     SDRNLVFYFFGGGGANLIVAILALLGFVPYASEFFILNIILFLVTVCLPIDGTDGNAI
                     REIVLYSKDSKTYQRFFANSLYNNPYITIDDFAKLTSKEKSFFSKFEKCLINLYFEVK
                     GEGSAFTIANHEVFDSNIQENIIHEYYKLLHKSSDWIIPQNLSLEEVVFTLSNYIYSK
                     NNKYLEKIKYLKKLVDFRQEEIIDFILNKEEVL"
     gene            18978..21086
                     /locus_tag="VVR63_000130"
     CDS             18978..21086
                     /locus_tag="VVR63_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="HEU6128197.1"
                     /translation="MKIPMIYQMENSECGLACCAMILNYFKYEISLNELREIYPSSRS
                     GYSLLSISKVLGDFNISSHAFKASVRDLKPLSFPLICFWESSHFIILEKISKNKFYIL
                     DPAKGRQRMSISEFERHYSNIILTFKKLDSFMSRKDNKKSPVLKYFFKYRNKLGILFF
                     VTALLYVIQSLVPIANRYIIDTNFKDDSYSSRMLFTILFIFTVSFSLMYLLRQIYVAS
                     LKYIMDKEISYDFMKHLIYLPYSFYEKRTLGDILFRANSIVYIREILSNNFIAAILDL
                     LMIVVYAVVLFSFSKYMVIFLISLSLALSIVMYPIIKISKNLIDKNIKEKVNVQNITS
                     EVISKNSDIKLTGEEEFWINKWDNFNTKQLIIGRKLDIHLSIVSSITNVLQIILPVLT
                     LIVGVNIKTFEQLTLGQIVAISTVSPYFISPIISLSDNYIQLMLLKGYFLRIEDVFNT
                     KSELIPERVSQDIKFDKKIELKDIWYKYGLFDDYVLKGINVTIKKGETVAIVGESGSG
                     KSTLAKILLGLLEPNIGSIEVDGVEKEEIGQTLYRKIFGAVLQNSTLSYGTLRENLTF
                     GHFVSDEELMTNLNSIGLSNVVKSLPLGLETIIAEEGNNFSGGQQQMILLARCLLSKP
                     SVVVLDEATSSLDNLSQQITTSYLSEIGTTKILIAHRLDTIKSADKILVMHNGEIVEI
                     GTHRELLELGGIYKQLYSNN"
     gene            21110..22849
                     /locus_tag="VVR63_000131"
     CDS             21110..22849
                     /locus_tag="VVR63_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HEU6128198.1"
                     /translation="MKIMKKKYWTLAILFFCLFNNSVTAQEIPKNLDGNITHTQTSES
                     FSESDEKQVDYSNKNQEEVDQNKFRIQIDKTELFVTTDKHLEKNCCKLELEPQINNDI
                     VNSESNNLLGEDNLDNKIKENVSHLDNRGGNIEHDKDNLESSIVRKYEWDIDKVTGGG
                     ESYKLYSKSNSKVSIAILDSGVDLQNTGLLKNLSNHSKNYVPNKGYLGKEEGEEGIIS
                     DIQDRLGHGTAVVAQIVGDDNINGVNPHVNINVYRIFGKSSASPDWIVKAIFDAVDDG
                     NDIINLSTGQYLMIDGEYEDGTNDFETFLKYKKAIDYANQKGVIIVAALGNDSLNVSN
                     QSDLLKLISSRKKVRKPGLVVDVPSYFSSTISVGGIDRLGNLSDFSNKGDSDAIYAPA
                     GSTLSLSELGLNNFINAEKYKEDWIFSATLGGYTYLYGNSFAAPKVSGAIAMIIDKYK
                     LKDQPYNYMFVKKILEETLPVKNGIKVLNIPNVLRYDLNMLQLEYKNEQSWDSFIDNV
                     NLIELEERIQTTIGIKQINTHNIITIAREGYSQNYLPNTSENTYNSLQVSLVGVLLLF
                     ISMVNILWAKKSK"
     gene            22900..23667
                     /locus_tag="VVR63_000132"
     CDS             22900..23667
                     /locus_tag="VVR63_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HEU6128199.1"
                     /translation="MSQKLNHLDVGEFVLLLPEHLRSEEEHYKSVFEDDLTSRMSSQD
                     ERQQMTATVGYLESGQDRFVYNTTPISYQQFLKDPIIIVITPQSTGPQSILFWIDAVQ
                     NYVLFNQLSDAQELIQRQGIENWVSEMQTGYHNYITLLDNIQRERWVMLAGAVLGIAT
                     SILLFNTMNRLYFEEFRRAIFIKRIAGLRFLEIHRTYLFAQLGVFLLGFVASVFLQVE
                     VGVAFLVLLLFTGLSLLQLHVQMQKENKMSILVLKGG"
     gene            23669..24301
                     /locus_tag="VVR63_000133"
     CDS             23669..24301
                     /locus_tag="VVR63_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6128200.1"
                     /translation="MIELKQVSKSFGERELFSNLSMTFEAGKVYALIGSSGSGKTTLM
                     NMIGKLEPYDGTIFYRGKDLANYKSSDFFRHELGYLFQNFGLIENQSIEENLKLGLIG
                     QKLSRSEQRLRQKQALEQVGLAYLDLDKRIFELSGGESQRVALAKIILKNPPFILADE
                     PTASIDPATSQLIMEILLSLRDDNRLIIIATHNPAIWEMADEVFTMDHLK"
     gene            complement(25246..25659)
                     /gene="ndk"
                     /locus_tag="VVR63_000134"
     CDS             complement(25246..25659)
                     /gene="ndk"
                     /locus_tag="VVR63_000134"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HEU6128201.1"
                     /translation="MEQTFFIIKPDGVKRGLVGEVLKRIEQRGFTIEKLEFRSQVSEE
                     LIDQHYQDLVGQSFYLPIREFMTSGPVLVGVISGPKVIETWRTMMGATRPEEALPGTI
                     RGDFAKAAGENEVIQNVVHGSDSEESAKREIALWF"
     gene            complement(25770..29447)
                     /gene="rpoC"
                     /locus_tag="VVR63_000135"
     CDS             complement(25770..29447)
                     /gene="rpoC"
                     /locus_tag="VVR63_000135"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HEU6128202.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYRGIVCDRCGVEVTRTKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLR
                     EYGYGSFVAKMGAEAIQDLLKQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFY
                     KSGNKPEWMILNILPVIPPDLRPMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIVQNVKAAKRLVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARILMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEEA
                     GREGEGMVFKDRDEAVMAYRNGYVHLHSRVGIATDSLNKPWTEEQRHKVLLTTVGKIL
                     FNDIMPEGLPYLQEPNNANLTEGVPAKYFLPLGGAIKEAISNLELNPPFKKKNLGNII
                     AEIFKRFRTTETSALLDRMKNLGYHHSTLAGLTVGIADIPVVDDKAEIIEESHKRVEQ
                     ITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIANQDPKNPIVMMMDSGARGNISN
                     FSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLEERLNGRYTKKTVKHPE
                     TGAVIIGPNELITEDKAREIVNAGVEEVTIRSVFTCNTRHGVCRHCYGINLATGDAVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEIFEARNPKGEAVI
                     TEVKGQVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQVARGAALTEGS
                     IQPKRLLAVRDVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKVRVMDPGDT
                     DLLMGTLMDINDFTDANKDVLIAGGVPATGRPVLMGITKASLETNSFLSAASFQETTR
                     VLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPHAVNEEEYLNPPVEEEG
                     NEETTEVVVDTAVETVEETVE"
     gene            complement(29480..33091)
                     /gene="rpoB"
                     /locus_tag="VVR63_000136"
     CDS             complement(29480..33091)
                     /gene="rpoB"
                     /locus_tag="VVR63_000136"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEU6128203.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFKAFLDHG
                     LKEVFEDVLPISNFTDTMELEFVGYEIKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELESDSKDITYTRIDRTRKIPFTTLVRALGFSGDDEIFDIFGDSELVR
                     NTVEKDIHKNPMDSRTDEALKEIYERLRPGEPKTAESSRSLLVARFFDPRRYDLAAVG
                     RYKINKKLNVKTRLLNQTIAEPLVDPETGEILVEAGTIMTRSVIESIESHLDGDLNKI
                     VYIPNDAAVVTEPVVLQKFKVIAPTDPDRVVTIIGNANPDDKVRTVTPADILAEMSYF
                     LNLAEGLGRVDDIDHLGNRRIRAVGELLANQVRLGLSRMERNVRERMSVQDNEVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSYGHLNKYGFVQTPYRKVDRETGVVTNEIV
                     WLTADEEDEYTVAQANSRLNEDGTFAEKIVMGRHQGVNQEYPANIVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPYVGTGMEYQAAHDSGAAVIAQY
                     DGKVTYADADKVEVRREDGSLDVYHIQKFRRSNSGTAYNQRTLVKVGDVVEKGDFIAD
                     GPSMENGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKDDVYTSVHLEEYESETRDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGADGVVRDVKIFTRVNGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARTLGIHIATPVFDGASSEDLWSTVKEAGMDSDAKTILYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSTVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDINGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDQ
                     EVELRDLDEGMDEDVIHVDDLEKAREKAAQEAKAAFEAEEAEKATKAEATEEAAEQE"
     gene            33507..33577
                     /locus_tag="VVR63_000137"
     tRNA            33507..33577
                     /locus_tag="VVR63_000137"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:33539..33541,aa:Cys,seq:gca)
     gene            complement(33775..35106)
                     /locus_tag="VVR63_000138"
     CDS             complement(33775..35106)
                     /locus_tag="VVR63_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HEU6128204.1"
                     /translation="MEDPSSQNLLLQFVLLFILTVLNAFFSATEMAMVSLNRARVEQK
                     AEEGDRRYIRLLKVLENPNHFLSTIQVGITLITILSGASLTNTLGRVIASWLGNGETA
                     QAVATFLSLAFLTYISIVFGELYPKRIALNLKDALAIRTAPIIIGIGKLVSPFVWLLA
                     ASTNFLSHLTPMSFDDADEKMTRDEIAYMLTNSEETLDADEIEMLQGVFSLDELMARE
                     VMVPRTDAFMVDIQDDSQAIIQSILKQNYSRIPVYDGDKDNVIGIIHTKSLLKAGFVD
                     GFDNIVWKRILQDPLFVPETIFVDDLLKELRNTQRQMAILLDEYGGMAGLVTLEDLLE
                     EIVGEIDDETDKAAIDVHQIGEDTYIVQGTMTLNDFNNYFDVELESDDVDTIAGYYLT
                     GVGTIPTTEKLSYELVSQNKQFILTNDKVKNGRVTKVKVQITEVEIEEETE"
     gene            complement(35335..36159)
                     /gene="endA"
                     /locus_tag="VVR63_000139"
     CDS             complement(35335..36159)
                     /gene="endA"
                     /locus_tag="VVR63_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-entry nuclease EndA"
                     /protein_id="HEU6128205.1"
                     /translation="MNKKTRQTLIGLLVLLLLSTGSYYIKQMPSAPNSPKTNLSQKKQ
                     ASEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIVNGNKTNLDAKVSSKPYADNKTK
                     TVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
                     LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRV
                     RYRVTLYYASNEDLVPSASQIEAKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ"
     gene            complement(36198..36386)
                     /locus_tag="VVR63_000140"
     CDS             complement(36198..36386)
                     /locus_tag="VVR63_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEU6128206.1"
                     /translation="MNKKSSYVVKRLLLVIIVLILGTLALGIGLMVGYGILGKGQDPW
                     AILSPAKWQELIHKFTGN"
     gene            complement(36379..37662)
                     /gene="murA"
                     /locus_tag="VVR63_000141"
     CDS             complement(36379..37662)
                     /gene="murA"
                     /locus_tag="VVR63_000141"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEU6128207.1"
                     /translation="MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASEGKTVLQ
                     NVPILSDVFIMNQVVGGLNAKVDFDEEAHLVKVDATGDITEEAPYKYVSKMRASIVVL
                     GPILARVGHTKVSMPGGCTIGSRPIDLHLKGLEAMGVKISQTAGYIEAKAERLHGAHI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETIT
                     ITGVEKLHGTTHNVVQDRIEAGTFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVE
                     VIEEDEGIRVRSQLENLKAVHVKTLPHPGFPTDMQAQFTALMTVAKGESTMVETVFEN
                     RFQHLEEMRRMGLHSEIIRDTARIVGGQPLQGAEVLSTDLRASAALILTGLVAQGETV
                     VGKLVHLDRGYYGFHEKLAQLGAKIQRIEASDEDE"
     gene            complement(37686..37916)
                     /locus_tag="VVR63_000142"
     CDS             complement(37686..37916)
                     /locus_tag="VVR63_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014017351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HEU6128208.1"
                     /translation="MIQLLFTLSSHMLFIYVSFYLLKDLVRWEKVLKVTDENTRKVRL
                     LVAFFSIVIGYILSSFFISLYHLWQEALRGLL"
     gene            complement(37974..39011)
                     /locus_tag="VVR63_000143"
     CDS             complement(37974..39011)
                     /locus_tag="VVR63_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HEU6128209.1"
                     /translation="MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLK
                     VNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFTDIRSAQETTGGSSDVEFMRINQ
                     FYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
                     DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVIS
                     NVPISFSTAGIGGPSAGLMFSLAIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGID
                     KKVVASARAGAAIFFTPDNPVSEEEQKAHPDAKNNYQTALEAAKTIKTDMKIVPVKTL
                     QDAIDYLKNNP"
     gene            complement(38995..39483)
                     /gene="coaD"
                     /locus_tag="VVR63_000144"
     CDS             complement(38995..39483)
                     /gene="coaD"
                     /locus_tag="VVR63_000144"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HEU6128210.1"
                     /translation="MSDKIGLFTGSFDPMTNGHLDMIERASRLFDKLYVGIFFNPHKQ
                     GFLPLENRKRGLEKAVKHLGNVKVVSSHDELVVDVAKRLGATCLVRGLRNASDLQYEA
                     SFDYYNHQLSSDIETIYLHSRPEHLYISSSGVRELLKFGQDIACYVPESILEEIRNEK
                     KD"
     gene            complement(39473..40012)
                     /gene="rsmD"
                     /locus_tag="VVR63_000145"
     CDS             complement(39473..40012)
                     /gene="rsmD"
                     /locus_tag="VVR63_000145"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HEU6128211.1"
                     /translation="MKIVSGIYGGRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFEGGR
                     VLDLYAGSGGLSIEAVSRGMSSAVLVERDRKAQTIVAENIQMTKEVGKFQLLKMDAER
                     ALEQVSGEFDLVFLDPPYAKEQIVADIEKMAERELFSEDVMVVCETDKAVELPEEIAC
                     LGIWKEKIYGISKVTVYVR"
     gene            complement(40077..41069)
                     /locus_tag="VVR63_000146"
     CDS             complement(40077..41069)
                     /locus_tag="VVR63_000146"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HEU6128212.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLKDKLEVVEVQGPILSKVGDGM
                     QDNLSGVENPVSVKVLQIPDATYEVVHSLAKWKRHTLARFGFGEGEGLFVHMKALRPD
                     EDSLDATHSVYVDQWDWEKVIPNGKRNIVYLKETVEKIYKAIRLTELAVEARYDIESI
                     LPKQITFIHTEELVERYPDLTPKERENAICKEFGAVFLIGIGGELPDGKPHDGRAPDY
                     DDWTSESENGYKGLNGDILVWNESLGGAFELSSMGIRVDEETLRRQVEITGDEDRLEL
                     EWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKRHIGEVQTSVWPQEVRDTYENIL"
     gene            complement(41181..41864)
                     /locus_tag="VVR63_000147"
     CDS             complement(41181..41864)
                     /locus_tag="VVR63_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HEU6128213.1"
                     /translation="MNHTIIHDRAGLNQFYAKVYAFVGLGIGLSALVSGLMLTVFQSQ
                     LVYFLMQGRLWLTIATFAELALVFVASSMASRNSPAALPVFLLYSVLNGFTLSFVVAF
                     YTPGTVLSAFVSSALLFFVMAAVGIFTKKDLSGIGRAMMAALIGLLIAMVVNIFLASG
                     FFDYMISVAMVLVFSGLIAWDNQKIRLAYEQSQGRVATGWVVSMALSIYLDFINLFLS
                     ILRIFGRND"
     gene            complement(41920..42660)
                     /locus_tag="VVR63_000148"
     CDS             complement(41920..42660)
                     /locus_tag="VVR63_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HEU6128214.1"
                     /translation="MTIITSKANSVVKNAKKLRQKKYRKSAYLIEGWHLFEEAVQAGV
                     TIEKIFALENYRDQLATFSQTVWVSEDILLDLADSQTPQGIVAVVQKEEVGQADLSQG
                     KFLFLEDVQDPGNVGTIIRTADAAGFTGVIVSDKSADIYSLKTLRSMQGSHFHLPIYR
                     MTSQALLDETKKVAIPVLATTLSKDSVDYRELPSIENFVLVMGNEGQGISPLMAESAD
                     QLVHISMKGQAESLNVAVAAGILIFHLS"
     gene            42694..42972
                     /locus_tag="VVR63_000149"
     CDS             42694..42972
                     /locus_tag="VVR63_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HEU6128215.1"
                     /translation="MQKVRMIAQGRVQGVGFRWGVYSLALEIGGITGRVWNNDDGTVE
                     ILAQADSSAIMAKFIQEIRKGPTPFSKVSYLDVKLSNFPPYSDFKIAN"
     gene            43050..43976
                     /gene="yidC"
                     /locus_tag="VVR63_000150"
     CDS             43050..43976
                     /gene="yidC"
                     /locus_tag="VVR63_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEU6128216.1"
                     /translation="MKSIKRFALSAMGAAMLLVLTGCVNVDKTTGQPTGFIWNTIGAP
                     MAEAIKYFATDKGLGFGVAIIIVTIIVRLIILPLGIYQSWKATLHSEKMNALKHVLEP
                     HQTRLKEATTQEEKLEAQQALFAAQKEHGISMFGGVGCFPILLQMPFFSAIYFAAQHT
                     EGVAQASYLGIPLGSPSMILVACAGVLYYLQSLLSLHGVEDEMQREQIKKMIYMSPLM
                     IVVFSLFSPASVTLYWVVGGFMMILQQFIVNYIVRPKLRKKVREELAKNPPKASAFSK
                     PSGRKDVTPEQPTAITSKKKHKNRNAGKQRSR"
     gene            complement(44051..44845)
                     /gene="pflA"
                     /locus_tag="VVR63_000151"
     CDS             complement(44051..44845)
                     /gene="pflA"
                     /locus_tag="VVR63_000151"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HEU6128217.1"
                     /translation="MSEETIDYGQVTGMVHSTESFGSVDGPGIRFIVFLQGCHMRCQY
                     CHNPDTWAMESNKSRERTVDDVLTEALRYRGFWGNKGGITVSGGEALLQIDFLIALFT
                     KAKEQGIHCTLDTCALPFRNKPRYLEKFDKLMAVTDLVLLDIKEINEEQHKIVTRQTN
                     KNILACAQYLSDIGKPVWIRHVLVPGLTDRDDDLIELGKFVKTLKNVDKFEILPYHTM
                     GEFKWRELGIPYSLEGVKPPTADRVKNAKKLMDTESYQDYMKRVHG"
     gene            complement(44971..46221)
                     /locus_tag="VVR63_000152"
     CDS             complement(44971..46221)
                     /locus_tag="VVR63_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HEU6128218.1"
                     /translation="MKTPFINREELEAIVAEFPTPFHLYDEKGIREKARAVNQAFSWN
                     KGFKEYFAVKATPTPAILKILQEEGCGVDCSSYVELLMSHKLDFLGSEIMFSSNNTPD
                     KEYAYARELGATINLDAFEDIEHLERVAGIPEIISCRYNPGGVFELGTDIMDNPGEAK
                     FGMTKDQLFEAFAILKEKGAKTFGIHSFLASNTVTHLYYPELARQLFELAVEIKEKLG
                     IWLDFINLSGGIGVNYRPDQEPNDIALIGEGVRKVYEEVLTSAGLGQVKIFTELGRFM
                     LAPHGALVTRVTHKKETYRTYLGVDASAVNLMRPAMYGAYHHISNVTHPDGPAEAVDV
                     VGSLCENNDKFAVNRELPHTEIGDLLVIHDTGAHGFSMGYQYNAKLRSAEILYTEEGK
                     ARQIRRAERPEDYFATLYGFDFEE"
     gene            complement(46288..47115)
                     /gene="purR"
                     /locus_tag="VVR63_000153"
     CDS             complement(46288..47115)
                     /gene="purR"
                     /locus_tag="VVR63_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004242125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HEU6128219.1"
                     /translation="MKLRRSDRMVVISNYLINNPYKLTSLNTFAEKYESAKSSISEDI
                     VIIKRAFEEIEIGHIQTVTGAGGGVIFTPSISSQDAKEMVEDLRTKLSESDRILPGGY
                     IYLSDLLSTPAILKNIGRIIAKSFMDQKIDAVMTVATKGVPLANAVANVLNVSFVIVR
                     RDLKITEGSTVSVNYVSGSSGDRIEKMFLSKRSLKAGSRVLIVDDFLKGGGTVNGMIS
                     LLREFDSELAGVAVFADNAQEEREKQFDYKSLLKVTNIDVKNQAIDVEVGNIFDEDK"
     gene            complement(47382..48323)
                     /locus_tag="VVR63_000154"
     CDS             complement(47382..48323)
                     /locus_tag="VVR63_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HEU6128220.1"
                     /translation="MKISHMKKDELFEGFYLIKSADLRQTRAGKNYLAFTFQDDSGEI
                     DGKLWDAQPHNIEAFTAGKVVHMKGRREVYNNTPQVNQITLRLPQAGEPNDPADFKVK
                     SPVDVKEIRDYMSQMIFKIENPVWQRIVRNLYTKYDKEFYSYPAAKTNHHAFETGLAY
                     HTATMVRLADAISEVYPQLNKSLLYAGIMLHDLAKVIELTGPDQTEYTVRGNLLGHIA
                     LIDSEITKTVMELGIDDTKEEVVLLRHVILSHHGLLEYGSPVRPRIMEAEIIHMIDNL
                     DASMMMMSTALALVDKGEMSNKIFAMDNRSFYKPDLD"
     gene            complement(48313..49569)
                     /locus_tag="VVR63_000155"
     CDS             complement(48313..49569)
                     /locus_tag="VVR63_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HEU6128221.1"
                     /translation="MESLLILLLIANLAGLFLIWQRQDRQEKHLSKSLEDQADHLSDQ
                     LDYRFDQARQASQLDQKDLEVVVSDRLQEVRIELHQGLTQVRQEMTDNLLQTRDKTDQ
                     RLQALQESNEQRLEQMRQTVEEKLEKTLQTRLQASFETVSKQLESVNRGLGEMQTVAR
                     DVGALNKVLSGTKTRGILGELQLGQIIEDIMTPAQYEREYATVENSSERVEYAIKLPG
                     QGDQEYVYLPIDSKFPLADYYRLEEAYETGDKDEIERCRKSLLASVKRFARDIRNKYI
                     APPRTTNFGVLFVPTEGLYSEIVRNPVFFDDLRREEQIIVAGPSTLSALLNSLSVGFK
                     TLNIQKSADHISKTLASVKTEFGKFGGILVKAQKHLQHASGNIDELLNRRTIAIERTL
                     RHIELSEGEPALDLLHFQENEEEYED"
     gene            complement(49571..50233)
                     /locus_tag="VVR63_000156"
     CDS             complement(49571..50233)
                     /locus_tag="VVR63_000156"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HEU6128222.1"
                     /translation="MSEYKLSENNWTRVAVFAGGNRGHYRTDFDAFVGVDRGSLWVLE
                     EDLPLALAVGDFDSVTEEERQVIQKGAQYFVQARPEKDDTDLELALLTIFEQNPQAQV
                     TIFGALGGRIDHMLANVFLPSNPKLAPYMHQIEIEDGQNLITYCPEGISQLEPRSDYD
                     YLAFMPVRDSQLTILGAKYELTEENFFFKKVYASNEYIDREVSVTCPDGYVVVLHSKD
                     RR"
     gene            complement(50196..50852)
                     /locus_tag="VVR63_000157"
     CDS             complement(50196..50852)
                     /locus_tag="VVR63_000157"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HEU6128223.1"
                     /translation="MSQYKIAPSILAADYANFEREIKRLEATGAEYAHIDIMDSHFVP
                     QISFGAGVVESLRPHSKMVFDCHLMVSNPEHHLEDFARAGADIISIHVEATPHIHGAL
                     QKIRSLGVKPSVVINPGTSVEAIKHVLHLVDQVLVMTVNPGFGGQAFLPETMDKVREL
                     VALREEKGLNFEIEVDGGIDDQTIAQAKEAGATVFVAGSYVFKGEVNERVQTLRKQLD
                     "
     gene            complement(50863..51741)
                     /gene="rsgA"
                     /locus_tag="VVR63_000158"
     CDS             complement(50863..51741)
                     /gene="rsgA"
                     /locus_tag="VVR63_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HEU6128224.1"
                     /translation="MQGQIIKALAGFYYVESDGQVYQTRARGNFRKKGHTPYVGDWVD
                     FSAEENSEGYILKIHERKNSLVRPPIVNIDQAVVIMSVKEPDFNSNLLDRFLVLLEHK
                     GIHPIVYISKMDLLEDRGELDFYQQTYGDIGYDFVTSKEELLSLLTGKVTVFMGQTGV
                     GKSTLLNKIAPDLNLETGEISDSLGRGRHTTRAVSFYNLNGGKIADTPGFSSLDYEVS
                     RAEDLNQAFPEIATVSRDCKFRTCTHTHEPSCAVKPAVEEGVIATFRFDNYLQFLSEI
                     ENRRETYKKVSKKIPK"
     gene            complement(51743..52615)
                     /gene="rsmA"
                     /locus_tag="VVR63_000159"
     CDS             complement(51743..52615)
                     /gene="rsmA"
                     /locus_tag="VVR63_000159"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HEU6128225.1"
                     /translation="MRIADYSVTKAVLERHGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DDQVNVIEIGPGIGALTEFLAERAAQVMAFEIDHRLVPILADTLRDFDNVTVVNEDIL
                     KVDLAQHIQNFKNPDLPIKVVANLPYYITTPILMHLIESGIPFCEFVVMMQKEVADRI
                     SAQPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRPEPAVAVED
                     ENFFFKVSKASFTHRRKTLWNNLTGYFGKTEEVKDKLTKALDQAGLSPSVRGEALSLA
                     EFAGLADALKGQGL"
     gene            complement(52746..53054)
                     /locus_tag="VVR63_000160"
     CDS             complement(52746..53054)
                     /locus_tag="VVR63_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6128226.1"
                     /translation="MCEKIRIRRVSDYPSARGGLEDILIMENMTNHLLLVQIRVHGYL
                     LDFASIEGQRQKHYRLKNLPQMVELTVDDVEEDVDLTLPENRSYQEADFFERMFRENC
                     "
     gene            complement(53047..53688)
                     /locus_tag="VVR63_000161"
     CDS             complement(53047..53688)
                     /locus_tag="VVR63_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6128227.1"
                     /translation="MIDIQGLEKKFNDRAIFSGLNLKLEKGKVYALIGKSGSGKTTLL
                     NILGKLEKIDGGRVLYQGKDLKTIPTREYFRDQMGYLFQNFGLLENQSIKENLDLGFV
                     GQKISKVERLERQVGALEKVNLGYLDLEQKIYTLSGGEAQRVALAKTILKNPPLILAD
                     EPTAALDPENSEEVMNLLVDLKDENRIIIIATHNPLVWNKADEIIDMRKLAHV"
     gene            complement(53690..55720)
                     /locus_tag="VVR63_000162"
     CDS             complement(53690..55720)
                     /locus_tag="VVR63_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEU6128228.1"
                     /translation="MKRLFILISMVLVSLYMVITSVDHREEILFGNYPSVDVTGMMIN
                     QPVASREEVTEALSHLAVEHNSLIARRIVEPNEAGETRFTYATYGEGKLPEGLTISSK
                     ESAETSDLLGSYLIVSGSLDGVSLQTTLKELGYQGFVSNGEDPFSIVLLLTATPMVLL
                     SLAIFLLTFMSLTLIYRIKSLRQAGIRLIAGESLFGVALRPVLEDVRQLICSVLVSSL
                     LGLGILWYQGALFMATVQLVIIALLLYGLTLAGISTLLSVVYLLGLQENSLVDLLKGK
                     LPLKRIMTLMMVGQLLAVLVVGSSATALLPHYREMQEMERASNKWSQSSDRYRLSFGW
                     SSAFADEEGTRKDNREWQTFTEERLANTDSFYIMSNVDNFSDGAEVDLDGNRLSDYTP
                     SGNVIYVSPRYLIEEKITVSSEFMDKMQNLSEGEFGLILPESLREQSVYYQGLFTDYL
                     QNFSSESVEVTSQKHYLPQVRLAFTETGQERFLYNDGYKTTRQYLKDPIIVVLTPQAT
                     GTRPVAGMLWGTTANSALKLDRYGDSITALKEKGLYHKVSYLVKSQLFFAKVLNDKRV
                     EFYSLLIGTILTLSTAILLFDSMNLLYFEQFRRELMIKRLAGMTIYELHGKYLLAQGG
                     VLLLGLVLSSILTRDGLISALVVALFTLNALLILVRQDKKEEAGSMAVLKGK"
     gene            complement(55797..56093)
                     /locus_tag="VVR63_000163"
     CDS             complement(55797..56093)
                     /locus_tag="VVR63_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEU6128229.1"
                     /translation="MKQTVKKLALVASIAATLGGGVSVASAAVQYPEGGVWTYGSGNG
                     GAYSNYYHPSKYHSSTVVSRKTGSSDKGYAGAGGTSRAWIRTSWGEKVAFYYNV"
     gene            complement(56413..57312)
                     /locus_tag="VVR63_000164"
     CDS             complement(56413..57312)
                     /locus_tag="VVR63_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU6128230.1"
                     /translation="MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPS
                     LPKLAYIARRLGVPVYSLMPDFSALPSAYLELKYQILREPIYGKEEEYDKKEACLEEI
                     YKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMPQIIEKEAYSINDMLL
                     IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTQIENYFIIRDTLISGMCCLEKVG
                     VTDCFNDYLSCLQEIMDKTQDYQKKPLVFMFLWKQALRVERDFSLAESFYQSSKTFAK
                     LIGDGFLVKKLTEEWQEDVKKYL"
     gene            complement(57384..57944)
                     /gene="rnmV"
                     /locus_tag="VVR63_000165"
     CDS             complement(57384..57944)
                     /gene="rnmV"
                     /locus_tag="VVR63_000165"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HEU6128231.1"
                     /translation="MKEKISQVIVVEGRDDTVNLKRYFDVETYETRGSAINDQDIERI
                     QRLHQRHGVIVFTDPDFNGERIRRMIMTAIPTVQHAFLKRDEAVPKSKTKGRSLGIEH
                     ASYEDLKTALAQVTEQFEHESQFDISRSDLIRLGFLAGADSRKRREYLGETLRIGYSN
                     GKQLLKRLELFGVTLAEVEEAMKSYE"
     gene            complement(57944..58717)
                     /locus_tag="VVR63_000166"
     CDS             complement(57944..58717)
                     /locus_tag="VVR63_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HEU6128232.1"
                     /translation="MIFDTHTHLNVEEFAGREAEEIALAAEMGVIQMNIVGFDKPTIE
                     RALELVDEYEQLYATIGWHPTEAGTYTEEVEAYLLDKLKHPKVVALGEIGLDYHWMTA
                     PKEVQEQVFRRQIQLSKDLDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLE
                     WAEKFVDLGMTISFSGVVTFKKATDLQEAAKELPLDKILVETDAPYLAPVPKRGRENK
                     TAYTRYVVDFIADLRGMTTEELAVETTANAERIFGLDSK"
     gene            complement(59022..59915)
                     /locus_tag="VVR63_000167"
     CDS             complement(59022..59915)
                     /locus_tag="VVR63_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HEU6128233.1"
                     /translation="MVAQDPKAQDSTKPTAEKSTVKAPAQRVDVKDITHLTDEEKVKV
                     AILQANGSALDGATINVAGDGTATITFPDGSVVTILGKDTVQQSAKGESVTQEATPEY
                     KLENTPGGDKGGNTGSSDANANAGGGSQAGGSAHTGSQNSAQSQASKQLATEKESAKN
                     AIEKAAKNKQDEIKGAPLSDKEKAELLARVEAEKQAALKEIENAKTMEDVKEAETIGV
                     QAIATVTVPKRLVAPNAAPKTTSAPQATAGTMQDVTYQSPAGKQLPNTGSASSAALAS
                     LGLVVATSGFALLGRKTRRRK"
     gene            complement(60199..60333)
                     /gene="rpmH"
                     /locus_tag="VVR63_000168"
     CDS             complement(60199..60333)
                     /gene="rpmH"
                     /locus_tag="VVR63_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HEU6128234.1"
                     /translation="MKRTYQPSKLRRARKHGFRNRMSTKNGRRVLAARRRKGRKVLAA
                     "
     gene            complement(60478..61692)
                     /locus_tag="VVR63_000169"
     CDS             complement(60478..61692)
                     /locus_tag="VVR63_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEU6128235.1"
                     /translation="MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPA
                     EFGFTAPDEVIHDLIMNARDSEGYSDSKGIFSARKAIMQYCQLKKFPNVDIDDIYLGN
                     GVSELIVMSMQGLLDNGDEVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDD
                     IKSKITSNTKAIVLINPNNPTGALYPKELLLEIIEIARQNDLIIFADEIYDRMVMDGH
                     VHTPVASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRL
                     CSNVLAQQVVQTSLGGHQSVDELLLPGGRIYEQRNFIYNAIQDIPGLSAVKPKAGLYI
                     FPKIDRNMYRIDDDEQFVLDFLKQEKVLLVHGRGFNWQEPDHFRIVYLPRVDELAQIQ
                     EKMTRFLKQYRR"
     gene            complement(61848..62141)
                     /locus_tag="VVR63_000170"
     CDS             complement(61848..62141)
                     /locus_tag="VVR63_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6128236.1"
                     /translation="MMKNSFQKSNFLYYGIILVSVLVEVIMIWQLESLVPLLYPDFIG
                     FLVFHVLYHLILFLVAKRSGRWDYLMIWGLFLMFNLLYDSFLGLLFLGLSFGM"
     gene            62303..62755
                     /locus_tag="VVR63_000171"
     CDS             62303..62755
                     /locus_tag="VVR63_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEU6128237.1"
                     /translation="MAQRYQNIMVAIDGSKEADLAFVKGVHSALRNDAKLTIAHVIDT
                     RALQSVSTFDAEVYEELQVDAESLMKEYEKRAKDAGVADVHIVIEMGNPKTLLARTIP
                     DAEEVDLILVGATGLNAFERLLVGSSSEYILRHAKVDLLVVREQEKTL"
     gene            complement(62790..64178)
                     /locus_tag="VVR63_000172"
     CDS             complement(62790..64178)
                     /locus_tag="VVR63_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU6128238.1"
                     /translation="MEVKAVFFDIDGTLVNNRKSVLKSTKDAIKIVKEQGVLVGVATG
                     RGPFFVKELMDDLDLDFAVTYNGQYIFSKDRVLFTSPISKLHLRHLISYAKKEGTEIA
                     LGTKDAMLGSKIMSFGLGSFSQRISRFVPSVLTRTVSQSFNRMVSKVVPQKEEDLLHL
                     MNQPIYQVLMLMTPEESEKAAADFEDLKLTRSNPFASDVINQGNSKLEGIRRVGKEYG
                     FDLNQVMAFGDSDNDLEMLAGVGMSVAMGNGSSSVKEAAKHITTSNQQDGIHKALEHF
                     GVLSSEKVFVSRDYHFNKVKTFHHMMDERTQEEPRAWDLEGATHRAGFKIEELVEFVR
                     SASPSEEDFGQAVSQLHQALDKAAGKVAKKTPAQQDLIGQVDALIDTLYFTYGSFVLM
                     GVDPERIFDIVHQANMGKIFPDGKAHFDPVTHKILKPDNWEEKYAPEPAIKKELQRQL
                     KAYERHKERNKS"
     gene            64244..65206
                     /locus_tag="VVR63_000173"
     CDS             64244..65206
                     /locus_tag="VVR63_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HEU6128239.1"
                     /translation="MPKKILVLHTGGTISMQADASGAVVTSSDNPMNHVSNPLEGIQV
                     HALDFFNLPSPHIKPKHMLVLYQKIKEEADNYDGVVITHGTDTLEETAYFLDTMEVPH
                     MPIVLTGAMRSSNELGSDGVYNYLSALRVASDDRAADKGVLVVMNDEIHAAKYVTKTH
                     TTNVSTFQTPTHGPLGLIMKQEILYFKTAEPRVRFDLDHIQGLVPIISAYAGMTDELI
                     DMLDLEHLDGLIIQAFGAGNIPKETAQKLESLLQKGIPVALVSRCFNGIAEPVYAYQG
                     GGVQLQKAGVFFVKELNAQKARLKLLIALNAGLTGQALKDYMEG"
     gene            complement(65412..66422)
                     /gene="ccpA"
                     /locus_tag="VVR63_000174"
     CDS             complement(65412..66422)
                     /gene="ccpA"
                     /locus_tag="VVR63_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000990602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HEU6128240.1"
                     /translation="MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFSSLAKGIDDIAEMYKYNIVLANS
                     DEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
                     VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGL
                     VFESKYSYDDGYALAERLISSNATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSD
                     DSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREVLLPHGLTERSSTRK
                     RK"
     gene            complement(66847..67446)
                     /locus_tag="VVR63_000175"
     CDS             complement(66847..67446)
                     /locus_tag="VVR63_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU6128241.1"
                     /translation="MKVLVAEDQSMLRDAMCQLLTLQPDVESVLQAKNGQEAIQLLEK
                     ESVDIAILDVEMPVKTGLEVLEWIRSEKLETKVVVVTTFKRAGYFERAVKAGVDAYVL
                     KERSIADLMQTLHTVLEGRKEYSPELMEMVMTRPNPLTEQEIAVLKGIARGLSNQEIA
                     DQLYLSNGTIRNYVTNILSKLDAGNRTEAANIAKESGWL"
     gene            complement(67448..68545)
                     /locus_tag="VVR63_000176"
     CDS             complement(67448..68545)
                     /locus_tag="VVR63_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU6128242.1"
                     /translation="MLERLKRIHYMFWISLIFMIFPILSVVTGWLSAWHLLIDILFVV
                     AYLGVLTTKSQRLSWLYWGLMLTYVVGNTAFVAVNYIWFFFFLSNLLSYHFSVRSLKS
                     LHVWTFLLAQVLVVGQLLIFQRIEVEFLFYLLVILTFVDLMTFGLVRIRIVEDLKEAQ
                     VKQNAQINLLLAENERNRIGQDLHDSLGHTFAMLSVKTDLALQLFQMEAYPQVEKELK
                     EIHQISKDSMNEVRTIVENLKSRTLTSELETVKKMLEIAGIEVETDNQLDTASLTQEL
                     ESMASMILLELVTNIIKHAKASKAYLKLERTEKELILTVSDDGCGFAFLKGDELHTVR
                     DRVFPFSGEVSVISQKHPTEVQVRLPYKERN"
     gene            complement(68545..69282)
                     /locus_tag="VVR63_000177"
     CDS             complement(68545..69282)
                     /locus_tag="VVR63_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6128243.1"
                     /translation="MKRWLALSKIEFLLTKRQLIYYLLSVGMPTAFYLFFSGMYQDTP
                     GGPANFMRDYLISMTGFSMMSTAIFSFPAVLHTDKMNNWQKILRHSPVNMVEYYLSKI
                     TSMLVDYLVSILVVFTVGHFVRGVDMPLVKWVGAAILLILGSIAFVALGLTLTLLPTS
                     QLMSVVGNLLYLGLAVLGGLWMPVSLFPDWMQAIGKRLPSYQLMELIKTFLNEGGINL
                     SATVYLLVFSAVLFGLTIYLQGHKENA"
     gene            complement(69284..70168)
                     /locus_tag="VVR63_000178"
     CDS             complement(69284..70168)
                     /locus_tag="VVR63_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6128244.1"
                     /translation="MNMIKVESLNKNIKGKAILKGISFEVAEGECVALIGPNGAGKTT
                     LLDCLLGDKLVTSGQVSIQGLSVTSSQLDYIRGYLPQENVIVQKLKVKELIAFFQRIY
                     PNSLSDQEIDQLLQFDQQQKEQFAEKLSGGQKRLFSFVLTLIGRPKLVFLDEPTAAMD
                     TSTRQRFWEIVRDLKAQGVTILYSSHYIEEVEHTADRILVLNKGELIRDTTPLAMRSE
                     GIEKHFILPLAYKEVIEQSNLVENWSQKQDALQVVTREADAFWELLVQAGCGIQEIEV
                     NNRSLLDTIFEETQKGDN"
     gene            complement(70155..70349)
                     /locus_tag="VVR63_000179"
     CDS             complement(70155..70349)
                     /locus_tag="VVR63_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6128245.1"
                     /translation="MKRGIIYFFIGLSLLVWLVEMFTGWFDQTLLRQFIRGALGFGFM
                     IFVVFLMRMEWLKGEYHEYD"
     gene            complement(70346..70477)
                     /locus_tag="VVR63_000180"
     CDS             complement(70346..70477)
                     /locus_tag="VVR63_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000490981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine aminotransferase"
                     /protein_id="HEU6128246.1"
                     /translation="MFSGLDESFYHFPWELFAGFGMMSWLVREGLKLVGDVKKEFEE"
BASE COUNT        21508 a        15072 c        12918 g        21636 t
ORIGIN      
        1 gaccacaatt actcaatacc gaatacccct gaatggtttc tttttcatgc accaatatat
       61 tataataatc ttcatccaat aataaggctg ataaactagc atcttggtca aaatataagg
      121 gaatttctcg accgtccttc tttaatggat attctggtaa aatactaaat agttcaatca
      181 tagaatgaaa ctcaggatta gttgttgtaa atcgaaaaag ctgcgctttc tcatctttct
      241 gacttccttg atactctccc aattctaaaa agtgattcaa ggtagtataa aattccttat
      301 tttttacttc atcaatgatg accatatcat aatcttttgt tgtgcgactt ttaaatcctt
      361 gcgaatccaa tacgatagag gtagcagttc ccccaatcag aacataatag ttctgaaaat
      421 ccgcaaacat ttcttgaaaa ataactttcg tattagctgg catcatcttc tcccagatac
      481 tgtaatatca tattttctag tgcttcactc tcttcctcta tacgtgggtc atcatcatct
      541 tttaaggtca aataaagaga aatcgaatct acaaattgtt tatcatgatt atttttaaaa
      601 tcattccaaa actcagatac aaaaggacga tatttccata tctctagcat ctttcatttt
      661 aaaacatgct gagaaagtgg caaggataac tgattgaatt ttctctgcca tatgacatag
      721 ctagtatttt catccgtttc agctaaaaaa gttgaatgcg acaaagcata agcaccacca
      781 tatagaaggt tagaaacaga ttttatctgc tttatatcgc catctggcaa taaaatccgt
      841 tttttgatgg gattaaataa acatgacacg gattttaaga ataattcttt ctttgacacc
      901 gtatatgtgt aaagcttatt ttgcttgttt aaccaatata aagctttaaa agtcctcaaa
      961 cacctataaa ttgttgagtt tggaagtcca gtgacttgtg aaagcaaatc aacatttact
     1021 actttttgac cttttgtcaa taaaaaggca atccacgtta attgttcgct aggtgttaat
     1081 tccttaggga tttcagtatc attcgcattg agtactagtc ccaatggagg gaagaagagg
     1141 tttcccttaa agtctacaaa cggaactcta gcttgaagta attgcttttt ttcactgtct
     1201 gataacttcg aaaacaccaa aacaacatcc atattggctt tttcacccat agtgcgagcc
     1261 tgagtaacaa atgaactcaa actccccctt ctcttttctt taatcaataa aaatgattcc
     1321 ttatgaaaag tcatttgagt atactcaaac ctttttacaa aactgattgg taaagtcaaa
     1381 gtcagttcct caatactgac atcaacataa aaggattgaa aaattgacat tatctttttg
     1441 acattcatgt tttttcctta ttctatcatt tttattatat tttatcattc ggtataataa
     1501 aatataagtt ttttgataaa ataaccaaaa actactcgct atcccctctc acattaccct
     1561 acatatcgtt tgacatgcga ctgatagttc aggaaaactt caaggagaac ttttctctca
     1621 tccactatgc aggacttact atttcacttc tactcctata ggctcaattt gacacttttc
     1681 tttttcgaat tgctcatatg cctcctgaat agtgagttcg atttatccaa atttattttt
     1741 gtctattttg atgaatactt ccacgaagat agtctgaaaa tgaatttgca ccaattttcc
     1801 ttctcttttt aagcatatta ttccagatat gattgccctc ttattcagta ataaattacg
     1861 ctttaaacgc ttcaatcagt atatctcctg ttgtcatatg ttctaaagaa aattcttcta
     1921 catatggttt aacatctctt aggttattac ttcctaatat cccattatgc tttttcgcta
     1981 agaaaataga agtcgcttct cccttaccaa taatcttgtt actatcatga tttcttgtta
     2041 aatctctata taatgcgtat tcttcagttc caatgtctat gctcacaatc tcagctgaac
     2101 ccttagttac caactggtct atcctagatt ttaaatgggg aattgtaggt atattgattt
     2161 catcatacac ctcttgtgga ataacaattt tacccaaata gagcttttct aaaagatgtt
     2221 cagtgccaac ccataaaaat actgaaatac aatctgcatc aataaataca cgactagtca
     2281 aacgacaact cccccctctt catctagccc atatacaata tcatatctga aagcatctag
     2341 taacagttcc tcatacttcc cttgcgaaat tctgttattt tctaaaagtt gttcagttga
     2401 attaatatat tatcctgatg ccatttcttt tttactttct gacaaaggac gatataaact
     2461 tgtatcatag cctaatcttg aagctgtctc tataacacta atatccatat ttttaatttc
     2521 ttctgcatca aggtatccat cattcctcaa tctatataac atagctttat gactgatacc
     2581 ataaaactga cccaatttta taatatcttc tacttcaaga tgagttctat tggcattttc
     2641 tctgatttcc tcaaccatcc tatacagtga agatgggaaa attaaaaaat aagaagcaaa
     2701 ctgatccgct tttctttcag tttcatctcc ttcaccaatc aagataagac tgactgaact
     2761 cttcttcacc tcatcataat aaagatgata cagttcatgt gctaaagaaa atctttacct
     2821 tcctaatggc atgtctgaat tgactgcaat gagactgaac tgagttcctt tataacagac
     2881 tccgctaata ttctttccga gtccataaaa taccagcgtc aaattttcta tcttttgtac
     2941 caatttaaaa atatctatcg gcgattcacc atcagctccc aacttttttc taagatttga
     3001 agctttatta cttaaatcca ttcgtgatat tcctttcacc tttttccatt ttggcaatca
     3061 tgctttgatt caaagacaaa tactcagcaa tcttatcttg agtaagattt gaagatattc
     3121 taagttcttt tattcttttt ccaacatcac atacatttat cacatacatt tatcatattc
     3181 atacacctct cataaaaaga atagcacact cttgtcataa ttttttaaat aaaaaaatta
     3241 tgacaaaaca aggaagcaat ttattgatgc tgcttaaaaa tctaaaattg atgagttcct
     3301 atcaaaaatc gtatcttcaa cctcaaaaca gtacttaaag ctatccgact cggtttacat
     3361 tgtcaaattt agattttatt tgagcataac tttctagttt gctttctgat ttttgtttaa
     3421 tatagtagca aacattgaag gaaatatctc cacaaaaaaa cgcatactat taagcttttt
     3481 caagacctaa taatatgcgc tgttctgatt tgaaagacat tccattatta ttttactgta
     3541 atcaagccat ctggctctac tgtgaattct ggcttgtctg ccagtgttcc gtctggtttg
     3601 aggtagtacc agcctgttcc gtccgctgac tggataaagg catttgatac catggcgcct
     3661 tctttagcgt ctaagtagta ccaagtgtcc ttgtacttga cccagcctgt cttcatggca
     3721 ccttcttcgt tgaaatagta ccacttatca gcgattttct tccagcctgt agccatttcg
     3781 cctgagttgt cgaaccagta ccagttgccg tctgtgtgct tcctccagcg gtctgcaagc
     3841 atatagcctg aactgtcaaa gtagtaccaa gtgccattga ttttctcaaa cttgtctttt
     3901 ggataagagc cgtctgaatg tacgtaccag tagccagtgt cattcttctg ccagcctgtt
     3961 tcaatcgtca agccgttctc aatatcatac ttaaactgct cacggctaat gccccatttt
     4021 gccaagtaag ggtatggatc cacatggtct gagtggttgt ttggttggtt attcgtgcaa
     4081 tactcgtgcg ttttaattcc agctaaactc cctgtatcaa gcgttttcgg caaacctgct
     4141 tcatctgcta gattgcgtaa gagttcgata taaaggcggt agtccgtcat gaactcttct
     4201 ttagttgaat ggctttcaat cagttcaacc gctgcatagg tctcagcatt ccaaccgccc
     4261 ccaacgtccc aggcaccatt atcaacaggt cctacctgca tgatgcaacc gttcccaaca
     4321 atgtgcgaga aaaaacctaa ttctgggtct ttccgccagt gataatccgc ttcattctgt
     4381 acggttgaat gcggattccc agttgagtgt gcgtgtactt gcctatatgg ttgcacgccg
     4441 acttgaggca aatctgttct taatttactc acattaattt ccatattcta ctccttatca
     4501 attaaaacaa ctcatttttt acaatccaga accagaaact cctttatttc taccttacaa
     4561 agaagacaat cttagtcacg attaggcttg tagatagaac ctcaaaacgc actattttga
     4621 cactgtaaat aggactgaca aggtctgcat tctatctaca ataacacccc agactaaaaa
     4681 gcttttcaaa agtatatttt tacagtctct atatgtcctt ttcataaata ctatacttta
     4741 ttatatcata taaaagaagt caaaagtctg ttaaactatt ttcaacacca aactaaagaa
     4801 gagaacacaa gttttttcga tgttcactag aggaaatgga ttttattcag taaatccaac
     4861 taggattgca ctttggttgc caagattgcc tttccttctt ttatcaaggg atgacggaat
     4921 agtgagaagt acagttgaac tgtcatggca acccagataa gaggttcaca aaggataaca
     4981 cccttatatc ctgcccaagg aataatcaaa accacaaaaa cgatttttcc gattagttca
     5041 ataaagctag aaactagagg aaggatcttc tgccccaagc cctgcaagca attgcgataa
     5101 atcaacaaga ggctcaaaat gggataaaag gctgaactga tttgcagata gagacttcca
     5161 ttttctatca agtaaccatc tgtcgaacta gccaagaagg aaaccaaggc tggactggca
     5221 aaaaagagga aaatacaaac aaaaactgcc caggatatac ttaaacgact gccgattcga
     5281 agaccttgag caatgcggtc aggtcgctta gctcctagac tctgagaagc aaaggtcgtc
     5341 attgatgcag aaatagcggt cataggaaga agggcaaagg tcataatgcg tcgagctgcc
     5401 gtctgagcac taataatcac tgcaccaaat gtattaacag aagactgtaa aatcacactg
     5461 ccgatagata caattgaact catcaagccc atagccaaac cctgctccaa gagatccgcg
     5521 tacaagcttt tgtcccattt gaaatgttta aactgtggca agagttctgg cacactttta
     5581 cgaatataat aaaagcagag aaccgctgat aaaccttgcg aaataatggt agcaagtcct
     5641 gcggattgaa ctcccagatg caattgcgta ataaaataga gatccagaac cacattaacc
     5701 aaggcagaga aaatcagaaa tcccagggct gctagactgt caccaataga ccgcaacaag
     5761 cctgcaaaaa gattataagc aaagctgaca cctacacagg tcacaatcat agaaatatat
     5821 tgataagatt gaggaagaat ttctgcagga gtatctaagt attgcaagag aggatacaag
     5881 ccaagaaagc ccagcaacat aactagaatg ctcaaaagag cacctaaaat ccaggtggct
     5941 gctactgctt ccttgatttt agtgaaattc cgagccccat aataacgagc aatgacaatc
     6001 cccatgccat tgccaacacc aagtgtaaag cctacaatca ggtcaaaaat cgctgtcgtc
     6061 gctcctactg cagccaagga ttcttgacca agaaatcgtc caacaatcaa gacatcagca
     6121 gtgttataga gctgttgaaa aatatttgat agcaagattg gaaaggtgaa gcttaagagc
     6181 gagggaagaa tcggaccatg tatcaggtcc actgttcgtt ttttattcat aaagctatta
     6241 tatcagcttt ccagaggagc gacaagaaac agcaaactta tatatagcgg aatgaaataa
     6301 ggacagtcaa atcgattttt aacaatgttt tagaagtaga tgtgtactat tctagtttcg
     6361 atctattata gttggttgag tttggaatag tacgctgtag ctgctaaaac atttctagaa
     6421 attaatttga ctttcctaat aaagttgttc atatcttatt tcaagctact atatataatc
     6481 taaaaacttg aatcaaaaat cgaaaaagta gcggatttct ccactgcttt aacagcttat
     6541 tcttcaattt cgatttcaag ttcatcgcct aagtcaagcg gaacttcttc attcactgct
     6601 tcttctttct ttggctcatc ttttttgttt tcagtatctt gttctgaaac ttcttctcca
     6661 tcaatcaagc caaatttaga acggacttgc ttatcaattt catcaaagat ttctgggtgc
     6721 tctgccaagt atttcttagc attctcagaa ccttgcccaa ttttttcatc tttgtaagaa
     6781 taccaagccc ctgctttttt gataatatcc aaatcgcttg caatcttcaa aagctcacca
     6841 gtcttagaaa ttccttctcc gtacataatt tcaactacgg cttccttaaa cggtggagct
     6901 accttatttt ttacaacctt aatcttagtt tctttaccga cattggtttc tttttgatca
     6961 ccagttccct taatttgtgt attaccacga acatccaagc ggactgaagc atagaatttc
     7021 aaagcacgtc cgcccggtgt tgtttctgga tttccaaaca tcactccaac tttttcacgc
     7081 aattggttga taaaaatggc aattgttttg gttttattga tagaggcgcc aagtttacgc
     7141 atggcctggc tcatcatacg agcctgcaaa ccaacatggc tatctccgat atctccatca
     7201 atttccgcac gaggaacaag ggcagcaact gagtcgacta cgacaagatc aactgcacct
     7261 gagtcaatca attttcccgc aatctcaaga ccttgctctc ctgagtctgg ttgagacaag
     7321 agcaattcgt caatattgac accaagggcc gcagcataag ctggatcaag ggcatgttcc
     7381 gcatcgataa aggcagcaat cccaccttct ttttgcgctt gtgcaactgc atgaagggca
     7441 accgttgtct taccagatga ctctgggcca tagatttcga tgatacgtcc cttaggataa
     7501 ccacctgagc caagggcaat gtcaagagct aaagaacctg agctcatcac ttgcaccttt
     7561 tgctccgcac gttcacccaa acgcatgatt gatcctttac caaagtcttt ctcaatcaat
     7621 ttaagagcat cattcaaggc cttttcacgt tctgccccaa atttttttga aatttcttct
     7681 aatttttttg gttttttcgc cattctattc tcctacattc taatgatcct cagacctatc
     7741 tactattata tcaaaagtta gtcacttaat aaagccttgc gaactaggtt aaaggcatgc
     7801 ataaccgcaa tatgacgtac atctgctcgg cttctgcctc caatattaac cttgataacc
     7861 tcagttcctt gctcttgcgc caagcctatg aagactgtcc caactgggtg tccttctagg
     7921 ctatctggtc ctgccactcc ggtcaaacta attccaaaat cagactgggt cttgcttcgt
     7981 gcctgctcag ccatcttctg agctgtaaat tcagacacca caccatgttc ttccaaattc
     8041 ttggcaggaa tatccaacat ccttgatttt tcctccaagc tataggtcac aaaaccaccc
     8101 ttaaatatac ttgaagctcc agaaaaattc gccacggtag cttggaaaag acctgccgtt
     8161 aaactctctg cagccgcgat ggttttccct tgccttttca gttcttctac cacaatgctg
     8221 gctaaactag tttcttcccc ataaccatag caaaagtctc gtaaagaaat tccttcgaaa
     8281 gtctggcagt ccaagatttg attttccaag atatccagcg cttgattcgc ctcttcttga
     8341 ctgctagcct ttgttgacag acgtagagtg acttctcctg tcttggcata aggggccaag
     8401 gtaggatcga tctgattatc aattaaatca gccaaaatcg taaccaactg gctctcgcca
     8461 atcccaaaga aacgaagaac tcgggaatac agcttgctcc ctgtcatcaa cttgggtaga
     8521 agttggttta agaccatggg tttcaattca cttggcggac ctggaaggac gacataggtc
     8581 actccgtcta cttctaattt tcctccaaca gccagtcctg tttcgtttgg cagtggaatc
     8641 gctccttcta caatttgagc ttgtctttcg ttattcggtg ttcgggcata gtctggtcgc
     8701 agggcaaaaa agatatccaa cttctcctga gcctgaggat caaagactaa tgctttccct
     8761 aaaaatttaa ctagggtttg tttggttagg tcgtcctcag ttggccccaa accgcctgtc
     8821 aaaatcacca gactgctacg ttgactggca atctcaagca aagacaagag acgaacttca
     8881 ttgtctccta cagccgtctg aaaatataca tctaccccaa tctcagctag tttttccgac
     8941 aaaaactggg cattggtgtt gacaatctgt cctgtcaaaa tctctgttcc aacagcaatg
     9001 atttctgctt tcatgtttcc tcctacctat ctattcgtat ttttttgaaa aaatcgcagg
     9061 aattttccta cgattgattt ttttatttgt atcaaaagtt aattatcttc atcaccaaca
     9121 ggtgctctgc caaataaatc ttcaaataaa accgcattgg tttcaagctg agtaacttct
     9181 tcttgtccca aagaacgtcg gagtatattt tgcatttcca acatatgtgc tctcgaaaca
     9241 atctggtaag aaacaccttg aagtatctct ccttcaccct gcaactgctg agtttcaatg
     9301 gttttaaatg aatctttata gcctagcaag ttagggatac tttttgcaga caaatcaata
     9361 ttggtctgca tattgtcact caaagctttt agaatctctt gataatgacc aacgctattt
     9421 aaactgagag ctttttccat gactttttga ataacttcac gttgacgttt ttgacgacca
     9481 taatccccct caggatcttg gtaacgcatt cgtgcataga ctagggcttc ttctccccca
     9541 atatgttgct ccccaacacc gatagaaata gtattaaatt cttcttggtc actgatagaa
     9601 attgggaaac ctaggatatt attgactgta atacctccta ctgcatccac tagtttttgc
     9661 aaccctctca tattgaccat cacatagcga tcaatatgga tattcatcat tttttgaatg
     9721 gtttctatag caagctctgc tccaccatct gcatatgctg agttcagttt cgcttcatga
     9781 gcctgaccat tccctgattc aatgcgcgtc agaatatccc gctctaaact catcattgtt
     9841 gtttttttcg ttttaggatt cactgtcatc aagatcatgc tatcacttct accgacccaa
     9901 gtttcagttc gttcaacatt tccggtgtcc actcccatta acagaatggt tagaggttca
     9961 gtcgcttcaa taaccttggt ttcttcaccg atttttttat aggttttagc taaggtttct
    10021 gtcccttgtt gataaatagt ataagcaaaa acacctactc ctactacagt tacagaaagt
    10081 aaagctagca ccattccaat aattttttta accatatttc tactaaccta tcagtttacc
    10141 catcaagtaa acatcgataa atttcccttc ttctatatat gccccacgct cttggctacc
    10201 ttcaatgaca aagccatgct tttgataaag atggactgct gcttgattac gagtttggac
    10261 agtcagttgg agacgacgca gaatgccact tgcttgtgcc cactctatcg cttcttctag
    10321 caacaaactt cccaagccat tattccaata tctttttcca atcacaatga agagatctcc
    10381 aatatgacgg actctcttac gctgatcagc tgtaatattt acaataccag caattttgcc
    10441 atttaagaat gcaagtaagg ttatctgatt gtccgaacta gcttgcttgt tgaggaatat
    10501 ttccatctcc tcactagtca agagaatacc atctccgtct aggctggtaa agtctgtctc
    10561 caaactcaca cgatttaaaa aggccactaa ttcagctgca tctttgggct ctgcttccct
    10621 aatgagcaat tcatactcca tattgaagct cctctaacaa tttctcagca cgcaaaccct
    10681 ttgcctgaaa atttaaacgg cgtccatctg cttcttttag aatttccaat tctaaataag
    10741 catctggcaa ggcatctcct aagagatttc cccactcaat aacagtcacg ccgccaccaa
    10801 agataaactc atccaagtcg atagaatcag catctccttc aatacgataa acatctaggt
    10861 gataaagtgg aagtcgacct tcatactctc tcacgatagt ataggtggga cttttaatca
    10921 tttgagaaat ctgtaatcct tttgcaagtc ctttagtaaa ggtcgtttta cctgcaccca
    10981 gttctccagt taagattaaa acatcattct ttgctaatag atggcccaaa cgctccccta
    11041 aggcttgcaa ctcttcttca ttttttgtgt acatactctt attataccaa aaacttttct
    11101 tttgtgtcta ttttcctact aaacttatca tcataacatc cataaaaaac aggctttctc
    11161 taaaagaaaa tgagcgtaac aatgaccaat acaagatctc ggaaaatatg accataaaag
    11221 gaaacttcct tcttaaccga atttgggaca agataggctg caaaaaacaa gcccagtcca
    11281 atataaatca gaagtgagac aatggtcatt ggatttctta agaaaagaag tgttgctaaa
    11341 atagtcacca acactgtctt ttttctgtcc agcatagcaa gaaaatcgcg cacgtatttt
    11401 ttcaagggta aaaaaatcag caaatctagc ccaaatagga aaaagaagga tggcaataaa
    11461 aagtcaacta attcttgctg cagcgtattt ttgatgaaca agttatctga caaaacaaga
    11521 acagctccta acaaattaat taagagtaac atactgtaaa aaagcttcac cgacttctta
    11581 ctggctagga cactatggac ttcttgctta cgggtataaa gataatttac tccagcacag
    11641 attcctgaaa cgaaaaccat gcttccgatg aaaaaagctg tactttgttt aaaggacaag
    11701 atgcattcct tccataggaa acagctactc aaactgattt gaattaaagc taacaaaaat
    11761 aagattctca ttgatttcat cttctctctc ccttcctacc aatcattata ctaggagaaa
    11821 agagagaact gtttctaatc ttctcaaatg tctctttaag acgctaaaca aacactagag
    11881 actaatactc aatgaaaatc aaagatcaaa ctaggtagct agccacaggt tgctcaaaac
    11941 agtgttttga gattgcagat agagctgacg tgatttgaag agattttcga agaatataaa
    12001 tttgaaatca tgaaaatccg tcaaacgggt ggttgttttg tctcgcacct cacggagcga
    12061 gacggactca gagtcacata attataaggc tgatagtatt aatctaacta tcagccttac
    12121 aggttattta acgtttcaga aaaactataa tgtcaagatt aactaaacag tatctagttc
    12181 cttcaaataa ttttctatct tcatcaacat taaaggattg ttataaatct tacataactc
    12241 tcttgcttct atataataat ttttgacttg ttctctgtct agaaatttgg ctccagcatt
    12301 tcctacaaga ataagtagag gagccaattg gtagcttgtc tgtctttgtt tacagagttc
    12361 aatcgtttca agagcttctt ggatggcttc attatatttt tcctttgata ctaggtagtg
    12421 agcgtagttg taacgaactc tgatgtagcc aaataaaaac tcttgatggt ccaaattttt
    12481 tgtctgatac aactctatta aatgagagta gtttgcctca tattcttgtt cacgacccac
    12541 taaggaatag aaattagata gagtattcaa cgcctttaaa taaatcagag tatttgaaga
    12601 gacttttaat aatatatttt ccaatgacga aattgcctca cacttactgt catattgata
    12661 gaagtcaatt atagatttaa tccattcaag gtaagttcgg tcttctaatg ttagaaaagt
    12721 gcttcgttct acctctattt tataaagata ttctaaatcg tcataatttc tgtcatctaa
    12781 taggcgagca gatagatgtt tgaaattaga gaggttagac ttaacttcga tttgttcatt
    12841 gaaaaagtaa tccaaaggga cttcaagtcg ttgagagagt ttgaataaca agtctgcgga
    12901 gggaataaaa tgacctcttt caattttact aatctggctt tgttcacaaa ttccttctgc
    12961 aagagtttgt tgggagagtc tcaactcttt tcttttcaat ctgaatttct ctgcgagtgt
    13021 attcattaaa gataataaac cttcctattt gcttaatttc attataaagt ttttagttca
    13081 aaatagcaag ttaaaggaat aaataattct ttatggtaat aaacaaaaaa aaaaagttaa
    13141 aaattacata aaaatacttg actaaataaa atatatctgt tagaataaaa acaaggaaaa
    13201 agaaaggggt ttcattgcat gagaaaaaaa cgtggaatta aaaaattagt tacatttgca
    13261 ttgctaggtg tttttatgtt tagtaataca attccttacc aacagtttat tcagaagaat
    13321 aaacaattgg agattcgagt gcaatcgcaa aagaagtcca atggtcttga tgttgggaag
    13381 gcggattaaa acccgatatt ttgcacgaga atgagagaat tataatttat ctgaaaaaac
    13441 gaaaaatata gagcaactta tttaactttt tataaggagg agttattact tatgaccaac
    13501 tttaattcaa acgaaaaatt ttgtggaaaa agtttaaaat cattgtctgc tgatgaaatg
    13561 agtttaattt atggtgcatc tgatggtgca gagccacgtt ggacgcctac tcctattatt
    13621 ttgaaatcag ctgcagctag ctcgaaagta tgcattagtg cagctgtttc tggtattggg
    13681 gggctagtta gctacaataa tgattgtttg gggtaaatta aaatgaaaaa tgattttgta
    13741 atcggaaaga gtttgaaaga attatctctt gaagaaatgc aattggttta tggtggcaca
    13801 gatggtgctg accctagatc aacaattata tgttctgcta cattaagttt tattgcatca
    13861 tatttggggt cagctcagac tcgttgtggc aaagacaaca agaaaaaata aaatattcaa
    13921 ttttaaaaat aaaagttgct ctttattttc ctctctcgta actaataatt ttgagagagg
    13981 ttttttttta aaacaatagt aagtcgtata ggtttgaggt aagtaaatga aatataaaat
    14041 taaaaatgtg cataaaacat tgtttattaa ggaaagatat caaatattat ctgaacgaaa
    14101 tgataattcc ttaaataact tttcattaaa taattggcgt tctacaatgt caattatttc
    14161 tgaaaaaact tttgaagaaa tgttgaaatt aaataattac aataaaaaaa tattttctaa
    14221 cactgtgaac tatgattata ccgaggaaca gataagacta tattcagaat atgccaaaaa
    14281 ttcggaatgg tataaatttg cggagggttc atttgaaata tttagaaaac atccccaaag
    14341 aattaatttt aagaaagatt tttctagaat tttggaaccc tttattatta atttgcttaa
    14401 attaatcaat aattatctag agaataaaga atacgagtgg attgacaaga atggaaatat
    14461 tttttcctct ctagtatttt atttagaaga tttaatctat ccttggattg ttaaaccttt
    14521 ggttttagag ataaattcat tgcgtgaaaa aggtttactt gaaggggaat cggagcagca
    14581 acggtacaaa tattttataa cattgtttga caaggaagag aatatattaa atttttataa
    14641 caaatatccc gttttactga ggcaaatatc ggagtcttgt cttcggttct atacttattt
    14701 tatagaaatt ttatcaaatt tagaaaatga ttttagtgtg ctagaagaag aattagggct
    14761 aagggggaaa ttaaatgata taaaatttgg aaagggtgat acacacagcc aaggaaaaac
    14821 tgttttgata ctcttctttg atgacgcgaa aattgtttac aagcctaaaa atttaataat
    14881 caataactca ctaaatacta ttgctgagta tatccgaaag gttgatgaaa aaattaggat
    14941 aagaatacct cgaactattg cttattcgga tcacagctat gaagaattta ttgattatct
    15001 acctctagag caaaagaaaa aattacctga atattattat aattttggtg tgcttttagc
    15061 atttatatat ttatttaatg ggagtgatat acattttgaa aatttaattt cctatggaga
    15121 tatgcctgta ataatagact ttgaaacaat gttacagcaa cctctatttg atgataaaac
    15181 tggtcagagt ttgctggata ccctgtttca cagggtgact cgaactttgc ttcttccaac
    15241 agagggagta aaaagggagg atggtcttga tgttgagatg agtgctctta caggaaattt
    15301 taagaaggat gcttttaatg gtcaagtttt aattaattta aatactgata aggtaaagtt
    15361 tgatattggg aaaattgatt ttgaaggtgg gaaaaacctg cctgttcggg atggtgatat
    15421 agaatttgat aagtatataa aagatttcaa aaaaggtttt agggattttt atctgatatt
    15481 tgaagagtta aataaaacag aagaatttaa aatgctatta aaagcaaact tgtatggttt
    15541 aaagacaagg gtacttttta gagacacaaa tagctatgct tcagtactat cttttttata
    15601 tcatcctgat ttttatgaag aaatgttaga tagagaaaaa gcattggaaa atctctggag
    15661 caataagttt tctaatcaag gtattgtagc aagcgaatgt gaacaaatga ggttattaga
    15721 tattccgatt ttttatacag atacaaatat caatgaaatc tacgatgatt ttggaaatca
    15781 ttttatttcc ctacatcaat tttctggata tgactatttt atgaaatatt tacctaataa
    15841 taatttggaa aatttagaaa agcaacttga tatcattgaa atttattttc caagctttga
    15901 tcagcgaaaa aaaggatata aattaaactt atctaataga aaaaaactcc caaatgaaag
    15961 tttagttact attctgcata atgaagtaga aaatattgca gactctttgg ttattaataa
    16021 tatttatgac gaatatccaa tttggagtat acctgttaat tttaaaggtt ctaaatggtg
    16081 tcttgaacaa acgggtaatg atatgtatag gggtagagct ggaatattac tgtttatgta
    16141 ctatgtaaaa ttattgaaag ataaatcatc atatactcaa ctgtacaata aaatgttatc
    16201 tgcaattccg ccatctgttt ctttatctaa gaccacattt ggtttaactg gggatatagg
    16261 atatttcatt gttctatcca ttatagagga ttacgataca aatactctcg catgcttaaa
    16321 ttatataaag agtgttttaa ctgagcttga aaagactgat tttgcaagtg tttcaaacaa
    16381 gtctgactat attaatggtc ttctaccttt aattaataca ctggtaagat attataggaa
    16441 aggaatagag aaggaacgtg ttctaaggct agtattaagt ttaggtgata cgctatataa
    16501 tgatgtaagc gagagagata atagtaattt tggatatagt tttggccatg gactatcagg
    16561 tgtaattttt acattaaaaa atatttataa agtgacaaga cttaaaaaat ataaagaatt
    16621 aattttacaa ctagttccta gggagaaaat caaaattcat tctttgaagt ggtgtagtgg
    16681 agaatttggg acattagtta atcatcccca aagtgttcca gagggaattg tagctagttt
    16741 agataatgat acattttgcc atggaagtat ggccataata aatttttaca tcgactacat
    16801 gaaagaaatg gatactagta tggaattgga gtctttattg tgtagtgttg taatgaataa
    16861 atcaaaagaa ggagagtatc gtatcgtcca aacaagcaat ttcccagatt tttctttgta
    16921 tacaggtgtg actggtattg cttatacttt tttaaggtat atcgcactga atcagaatga
    16981 caaaaagata gttatcccct cattacttga aatctagctt aatttatagt tttgtttcta
    17041 aaatagaggt gtccactcat taagcaatat aaaaatacca agattgacta gtttaatatg
    17101 taattctata aaatattttt aatagtgtag cttttcgttg agataataat ataataaaga
    17161 aaagttctat tctaattgct aaacggcttg aggtatatgc tactgttata gaaatgattt
    17221 taaactaaaa tcaaaattac tccaaaaata gtattgattt tggtttaata caaaacatat
    17281 gtaataatgt gagtcaacaa aagtctgttt ttgtaccata ctatcttgaa aaatctacta
    17341 aattcaaatt gagaggatga attaaaatga ataaaatatt tatatatgca ggagtgcgaa
    17401 atcataactc taagacttta gagtatacta agagactttc aagtatcatt tctagtagaa
    17461 ataatgttga tatatctttc aggacacctt tcaattcaga gctagaaata tctaattctg
    17521 attcagaaga gttgtttaag aaaggaattg ataggcaaag taatgctgat gatggaggtg
    17581 ttataaaaaa agagttatta gagtctgata ttataattat ctcttctcct gtatatttac
    17641 aaaacgtatc tgtggacaca aaaaacttta ttgaaaggat tggggggtgg agccatcttt
    17701 ttcgattagc tggaaagttt gttgtaacat tagatgttgc tgagagtaac ggctctgata
    17761 atgtgtcaga atatcttaga gatatatttt catatatggg aggacagata ttacaccaag
    17821 tttcaattac caattcactc aaagatattg cagaggctca gttgatggag gcaacttata
    17881 aaattgaaga tgtacttgaa gggaaaatta agtacaaaac aacggattat caagaaagag
    17941 cttaccagac attaaaatta attttagaaa attatgattc cgaacatttt gagaagatgt
    18001 attgggagaa aaaacgcctt tttgaagcta atagtttaga ggaatggtat tatgttgaaa
    18061 atattaaata actctgtcat atatttatgt ttgattccgt tattgttcct attattgata
    18121 atttttccaa atgattcatt aatctattat tttcgattga ttttaatttc gttaatatca
    18181 attacattac atgaactagg tcatttttta gtgggaagat gtttatctta taaactagag
    18241 atgcttgcta ctcccttttt cttctatttc agaaaaaaaa tatatttcaa atttccagtg
    18301 ttattagcat tcggttattg tcaaatgagt aatagaaaca ttactaatga aaaaaatagt
    18361 gataggaatt tggtgttcta cttctttggg ggaggtggag ctaacctaat tgtcgcaata
    18421 ttagcacttt tgggatttgt gccgtacgca tcagaatttt ttattttgaa tataattctt
    18481 tttctagtta cggtatgttt accaattgat ggaacagatg gcaatgctat tagagagata
    18541 gttttgtatt caaaagattc aaaaacatat cagagattct ttgcgaacag tctctataat
    18601 aatccttata taacaatcga cgattttgca aaattaacct ctaaagaaaa atcttttttt
    18661 tcaaaatttg aaaaatgttt gataaacctt tactttgaag tgaaaggtga agggtcagca
    18721 tttacaattg ctaatcatga agtttttgat tcaaatattc aggaaaatat tatccatgag
    18781 tactataaat tactacataa atcttctgat tggattattc cacagaactt atctttagaa
    18841 gaagttgttt ttaccttgtc aaactatatt tactcgaaaa ataataaata tttagaaaag
    18901 attaagtatc taaagaaatt agtagatttt agacaagaag aaattatcga ctttattttg
    18961 aacaaggagg aagtattgtg aaaattccaa tgatatatca aatggaaaat tcagaatgtg
    19021 gattagcatg ctgtgccatg atattgaact attttaaata tgagatttct ttaaatgaac
    19081 tacgtgaaat ctacccatca tccagatctg gatattctct cctatctata agtaaagttt
    19141 taggagattt taatataagt tctcatgctt ttaaagcttc ggtaagagat ttaaaaccgc
    19201 tcagtttccc actcatttgc ttctgggaga gttctcattt tattattctt gaaaaaatta
    19261 gtaaaaacaa gttttatatt ttagatcctg caaaaggcag gcagagaatg tcaataagtg
    19321 aatttgaaag gcattattca aatatcattt taacatttaa aaagttagat agctttatgt
    19381 ctcgtaaaga taataagaag tcgcctgttt taaagtattt ttttaagtat aggaataagc
    19441 tagggatttt attttttgta acagcattat tgtatgtaat acaatcatta gtacctatag
    19501 ctaatagata cataattgac acgaatttca aggacgattc gtattcgtct agaatgttat
    19561 ttactatatt atttatattt actgtttcat tctcactaat gtatttatta agacagatat
    19621 atgttgcatc cttaaaatat ataatggata aagagattag ctatgatttt atgaaacatt
    19681 tgatatattt accttacagt ttttatgaaa aacgtacttt aggggatata ctttttagag
    19741 ctaactctat tgtttatata agagaaatac tatcaaataa ttttatagca gctatacttg
    19801 atttgttaat gattgtggtt tatgctgtgg ttttatttag cttttctaag tacatggtaa
    19861 tctttttaat atcactaagt ctagctctat ctattgtaat gtatccaatc ataaaaatct
    19921 caaaaaattt aattgataaa aatataaaag aaaaggttaa tgttcaaaat attacttccg
    19981 aagtaatttc taaaaatagt gatattaagc taactggaga agaggaattt tggattaaca
    20041 aatgggataa ttttaataca aaacagctca tcataggtcg aaaacttgat atacatttat
    20101 caattgttag tagtataacg aatgttttac aaattattct ccctgttttg acccttattg
    20161 taggtgtaaa tataaaaaca ttcgaacaat tgacgttagg acaaattgta gcaataagta
    20221 cagtctcacc atactttatt tctcctataa tttctttaag tgataactat atacaattaa
    20281 tgttattaaa gggatatttt ttaagaatag aggatgtgtt taatactaaa tccgaattaa
    20341 ttccagaaag agtcagtcaa gatataaaat ttgataaaaa aatagaatta aaagatattt
    20401 ggtataaata tggattattt gatgattatg ttttgaaagg aataaatgtt actattaaaa
    20461 aaggagaaac tgttgctatt gttggagaat caggttcagg taagagtaca ttagctaaaa
    20521 ttttattagg tttattagaa cctaatattg gttcaataga agttgatgga gtagaaaaag
    20581 aagaaattgg tcaaacattg tatagaaaga tttttggagc agtgttacaa aattcaaccc
    20641 taagttatgg taccttaaga gagaatttga catttggaca ctttgtttca gatgaagaat
    20701 taatgacaaa tctaaattca attggtctta gcaatgtagt taaatcttta cctcttggat
    20761 tagagacaat catcgctgaa gaaggtaata acttttctgg agggcagcag caaatgatac
    20821 ttttagctcg ttgtcttttg tcgaaacctt cggtagttgt tttggacgaa gcaacaagta
    20881 gtttagataa tttatctcaa caaattacaa cttcttactt aagtgaaatc ggtaccacta
    20941 agattttaat tgcccatcga ctagatacta tcaagtctgc agataagatc ttagtaatgc
    21001 ataatggtga aattgtagag attgggaccc atagagaact tcttgaacta ggaggcattt
    21061 ataagcaatt gtattcaaat aattagtttt tgattaaaag ggtaaattta tgaagattat
    21121 gaaaaaaaaa tattggactt tagcgatatt attcttttgt ttgttcaata attctgttac
    21181 tgctcaagaa atacctaaaa atcttgatgg caatataact cacactcaga ctagcgaaag
    21241 tttttctgaa tctgatgaaa aacaggttga ctattctaat aaaaatcaag aagaagtaga
    21301 ccaaaataaa tttcgtattc aaatcgataa gacagaatta tttgtaacaa cagataaaca
    21361 tttagaaaaa aactgttgta aattggaact tgaaccacaa ataaataacg atattgttaa
    21421 ctctgaaagt aataatttac taggcgaaga taatttagat aataaaatta aggaaaatgt
    21481 ttctcatcta gataatagag gaggaaatat agagcatgac aaagataact tagaatcgtc
    21541 gattgtaaga aaatatgaat gggatataga taaagttact ggtggaggcg aaagttataa
    21601 attatattct aaaagtaatt ctaaagtttc aattgctatt ttagattcag gagtcgattt
    21661 acaaaatact ggattactga aaaatctttc aaatcactca aaaaactatg tccccaataa
    21721 aggatattta ggaaaagagg agggagagga aggaataata tcagatattc aagatagatt
    21781 aggtcatggt acggctgttg tagctcaaat tgtaggggat gacaatatta atggagtaaa
    21841 tcctcacgtt aatattaacg tctatagaat atttggtaag tcgtcagcta gtccagattg
    21901 gattgtaaaa gcaatttttg atgctgtaga tgatggcaat gatattatca atcttagtac
    21961 tggacaatat ttaatgattg atggagaata tgaggacgga acaaatgatt ttgaaacatt
    22021 tttgaagtat aaaaaggcta ttgattacgc gaatcaaaaa ggagtaatta tagtagctgc
    22081 attagggaat gactccctaa atgtatcaaa tcagtcagat ttattgaaac ttattagttc
    22141 acgcaaaaaa gtaagaaaac caggattagt agttgatgtt ccaagttatt tctcatctac
    22201 aatttcggtc ggaggcatag atcgcttagg taatttatca gattttagca ataaagggga
    22261 ttctgatgca atatatgcgc ctgcaggctc aacattatct ctttcagaat taggacttaa
    22321 taactttatt aatgcagaaa aatataaaga agattggatt ttttcggcaa cactaggagg
    22381 atatacgtat ctttatggaa actcatttgc tgctcctaaa gtttctggtg cgattgcaat
    22441 gattattgat aaatacaaat taaaagatca gccctataat tatatgtttg taaaaaaaat
    22501 tctggaagaa acattaccag taaaaaatgg tataaaagtg ttaaatatac caaacgtatt
    22561 gagatatgat ttgaatatgt tacaattaga atataaaaat gaacaaagtt gggatagttt
    22621 catagataat gttaatttaa ttgagttgga agagagaatt caaactacta ttggaattaa
    22681 acaaataaac acacacaata ttattactat tgcccgagaa gggtactctc aaaattattt
    22741 acctaacact tcagaaaata catataattc attacaagtc agtttagttg gagtattact
    22801 actttttata agtatggtaa atattttatg ggctaaaaaa agtaaatgaa aataaaattt
    22861 ggagccctct gaaaaagtaa gtcctacagt tcaactaaaa tgagtcaaaa gttgaatcac
    22921 cttgatgtag gggagtttgt cttattgctg cctgaacacc tccgttcaga ggaagaacat
    22981 tataaatctg tttttgaaga cgacttaacc agtcgcatgt ctagtcaaga tgaacgacag
    23041 caaatgactg ctacggtagg ttatttagaa tcaggtcagg atcgttttgt gtataatacg
    23101 acccctattt cttaccagca gtttttgaaa gatccaatca tcattgttat aacaccccaa
    23161 tcaactggtc cacagtccat tttgttttgg atagacgcag tacagaacta cgttctcttt
    23221 aatcaattgt ctgatgccca ggagcttatc cagagacaag gcattgaaaa ttgggtctca
    23281 gaaatgcaaa caggttacca caactacatc acattattgg ataatatcca gagggaacgt
    23341 tgggtaatgc tagcaggagc tgtgcttggg attgcaactt caatcttgtt gtttaacact
    23401 atgaataggc tctactttga agaatttaga cgtgccattt ttatcaaacg cattgcaggt
    23461 ctcaggttct tagaaatcca tcgcacttat ctctttgctc aactgggtgt gtttttactg
    23521 ggatttgttg cgagtgtatt tcttcaggta gaggtaggag ttgctttctt agtcttgtta
    23581 ctctttactg gtctatctct tttacagtta catgtccaaa tgcagaaaga aaacaagatg
    23641 tccattcttg ttttgaaggg aggttaatat gattgaactt aaacaggtga gtaaatcttt
    23701 tggagaacga gagttatttt cgaatctttc aatgacattt gaggctggaa aagtctatgc
    23761 cttaattggt tcaagtggta gcggaaaaac aaccttgatg aacatgattg ggaaattaga
    23821 accttatgat gggacgattt tttaccgagg taaagacttg gccaattata aatcgagtga
    23881 ttttttccgt cacgaattgg gctacctctt ccagaacttt ggcttaattg aaaaccaaag
    23941 tattgaagaa aaccttaagc taggtctcat tggtcaaaag ttgagtcggt cggaacagcg
    24001 gttgaggcag aagcaggctt tagaacaggt cggcctggct tatcttgacc tagataagcg
    24061 catctttgag ttatcgggcg gagaatcgca acgagttgcc ttggcaaaaa ttatcttaaa
    24121 gaatccaccc tttattctgg cagatgagcc aacagcttca atagacccag caacctctca
    24181 gttgattatg gagattttgc tatctcttcg agatgataat aggctaatca ttatcgcaac
    24241 acataatccg gcaatttggg agatggctga tgaagtgttc acgatggatc atctgaaata
    24301 aaaatccttg tttttaattg cacgatgagt tactgaaata ttatcatgaa tcaagaattg
    24361 gagttaattt agaattgtac ttaatttaga attgtacttt attaatattg aggtaacttt
    24421 ttcttgataa aggaggaaat agtggagagg aagttagaat gaaaaaattc gacaattata
    24481 ttattgagaa gccttgcgat tctaattcag ataaactgca aaaaatctta ataattgaaa
    24541 gtttggtaga tgatattttg caattttctc tcagaatcaa taatagtgta ggagagattt
    24601 tcctcctaca accgttttaa aagaaaacta tctttattcc atgttatttt gaggaagata
    24661 ttgtgaaagt caaagatgat gataaagttg agtggaattt gttagaattt caaaaattta
    24721 gagcattttt ggcttagtaa tctgtgttga aggctcaaaa cctatggtaa aaaagtagct
    24781 ttgaaaacgt attgcctcca aagatttagt taaataatga tttaacacaa aaagaaatta
    24841 ttgaagttct ggaaagatgt tgtttcagta ttgagaaaag gtgggaaaaa cttgcgattt
    24901 tcacagagaa aggaagaaaa agtatagaaa tatagtcaat tgaaacaaga acaggacaaa
    24961 agaacctttt gtgccatatt tttctccttt cgctttacaa ttggcttgaa cacctttatt
    25021 gtatcgcgtt tggagttttt ttggtataac cttcgacgcg cacccgcata gcgggtgttt
    25081 ttttgtctcg cacctaacgg agcgagacga actaatagtc acttaatcaa aaaacgcacc
    25141 atatcaaaaa ctaaaaagtt tgatatcatg cgtcatgtct taaactaatt gactatactt
    25201 tctattcaaa tgagctttta accaattgat tgagccaatc cactcttaaa accaaagagc
    25261 aatttctcgc ttagctgact cttctgaatc tgaaccatgt acaacatttt ggataacctc
    25321 attttctcca gcagcttttg caaagtcacc tcgaatagtg cctggtaaag cttcttctgg
    25381 acgagttgca cccatcatgg tccgccaagt ttcgattact ttgggaccag aaatgacacc
    25441 cacaagaact ggacctgaag tcatgaattc acgaatcggt aggtaaaaac tctgaccaac
    25501 caagtcctga tagtgctggt caatcaactc ttctgaaacc tgtgaacgaa actccaattt
    25561 ttcgattgta aatccacgtt gttcgatgcg ctttaacact tcacccacta gccctctttt
    25621 tacaccatct ggtttgatga taaagaatgt ttgttccata cccgtctcct ttgtcagctt
    25681 ctttctttta ttttaccaca tttcgtggaa aaatggagaa agttttcaga agagagaatg
    25741 agagaaccct cgggttctct cattctctct tattctactg tttcttccac agtttcaacg
    25801 gcagtatcca caactacttc tgttgtttct tcatttcctt cttcctctac tggaggatta
    25861 aggtattctt cttcgttgac agcatgtggt tcaaggttac ggtaacgggc cataccagta
    25921 ccagctggga tgatcttacc gatgataaca ttttctttaa gtccaaggag atggtctttc
    25981 ttaccacgga tagctgcgtc agtaaggaca cgagttgttt cctggaagga agccgctgac
    26041 aagaaactgt ttgtttcaag tgaggctttg gtaattccca taaggactgg gcgacctgtc
    26101 gctggaactc cacctgcgat aaggacatct ttgttggcat ctgtaaagtc attgatatcc
    26161 atgagggtac ccatgagaag atctgtatca cctggatcca tgacacggac tttacggatc
    26221 atttgacgaa ccattacctc gatgtgtttg tcaccgattt ctaccccttg gctacggtaa
    26281 actttttgta cttcaccgag aaggtacgtt tcaactgaca agacatcacg aactgcaagg
    26341 agacgttttg gttggataga accttctgtc agagcagcac cacgcgctac ttggccccca
    26401 acttcgacac gcatacgagc tgtaaatgga acgacatatt caccttcgcc agtttcaccc
    26461 ttaacaaaga ctttcttggt acgagttgat gcatcttctt cgatagcagt aacttgtcct
    26521 ttaacctctg taataaccgc ttccccttta ggattgcggg cttcaaagat ttcttggaca
    26581 cgaggaagac cctgagtgat atcggtattt gaggcaaccc cacctgtgtg gaaggtacgc
    26641 attgtaagct gtgtaccagg ttccccgata gattgggcag cgattgtacc aactgcttca
    26701 ccaacttcaa ccgcatcacc agtcgccaag ttgataccgt aacagtgacg gcagacaccg
    26761 tgacgagtgt tacatgtaaa tacagaacgg atagtcactt cttccacacc agcattgaca
    26821 atttcacgcg ccttgtcttc tgtaatcaat tcatttggac caataatcac tgcaccagtt
    26881 tctggatgtt taacagtttt cttagtgtaa cgaccgttga gacgctcttc gagagactcg
    26941 atcatctctt ttccttctgc gatagaacgg atcaagagac cacggtcagt tccacagtcg
    27001 tcctcacgga tgataacgtc ttgggcaacg tcgaccaaac gacgagtcaa gtaacctgag
    27061 tcggctgtct taagggccgt atcggtcata cctttacgag caccgtgagt tgagaagaac
    27121 atttccaata ccgacaaacc ttcgcggaag tttgaaagga ttggcaattc catgatacgt
    27181 ccattcggag cagccatcag accacgcata ccggcaagct gtgagaagtt tgagatgtta
    27241 ccacgggctc cagagtccat catcataacg attgggttct taggatcttg attagcaatc
    27301 aagcgtttct caagtttttc acgggcagca cgccattcag ctgtaacagc attgtaacgc
    27361 tcgtcgtctg tgatcatacc acgacggaat tgtttggtga tttgttcgac acgtttgtgt
    27421 gattcttcaa tgatttcagc cttgtcatca acgactggga tatcggcaat acccactgtc
    27481 aatcctgcaa gagttgagtg gtggtaaccg aggttcttca tgcggtcaag tagggcagaa
    27541 gtttctgtcg tacggaaacg tttgaagatt tcagcgatga tatttccgag gtttttcttc
    27601 ttgaatggag ggttgagctc aagattgctg atagcttcct tgatagctcc accaagtggc
    27661 aagaagtatt tagctggaac accttctgtc aagttggcat tgtttggttc ttgcaagtat
    27721 ggtagcccct ctggcatgat atcgttgaag agaattttac caactgttgt aagcaagacc
    27781 ttatgtcttt gctcttctgt ccaaggcttg ttgaggctgt ctgttgcgat accaacacgt
    27841 gagtggaggt gaacataacc attgcggtaa gccataaccg cttcgtcacg gtctttgaag
    27901 accattcctt caccttcgcg accagcttct tccatggtca agtagtagtt acccaaaacc
    27961 atgtcctgag atggagtaac taccggtttc ccatctttcg ggttcaagat gtgctcagca
    28021 gctagcatga ggatacgagc ttctgcttgt gcttcttctg aaagtggtac gtggatggcc
    28081 atttggtccc cgtcaaagtc agcattgtag gcttcacaga caagtgggtg caagcgaaga
    28141 gccttaccat caatcaagac tggctcgaag gcttggatac ccaaacggtg aagggtcggt
    28201 gcgcggttca aaagcactgg gtgttcttta atcacttctt caaggatatc ccagatacgc
    28261 tcatctccgc gttccaccaa gcgtttagct gctttgacgt tttgcacgat atcacgggca
    28321 acgatttcac gcatgacaaa tggtttaaag agttcaatcg ccatttcacg tggcacacca
    28381 cattggtaca tcttaagagt tggaccaacg gcgataacgg aacgtcctga gaagtcaaca
    28441 cgtttaccga gcaagttttg acggaagcgt ccttgtttac ctttaagcat gtggctcaat
    28501 gatttcaatg gacggctacc tggtcctgtg attggacgac cacgacgacc attgtcaatc
    28561 aaagcgtcaa ctgcttcttg aagcatacgc ttctcatttt gaacgatgat acctggtgca
    28621 tttaactcaa gcaaacgagc caaacggttg ttacggttga taacacggcg gtaaaggtca
    28681 ttcaagtcag atgaggcaaa acggccacca tccaactgca acattggacg aagatctggt
    28741 gggataaccg gaaggatgtt aagaatcatc cattcaggtt tgtttccaga cttgtaaaag
    28801 gcatccaaaa catccaaacg acggatggct ttgacacgtt tttgtccagt agcagttttc
    28861 aattcttctt tgagttcagc aatttctttt tcaagatcta cttgcttcaa aaggtcttgg
    28921 atggcttccg cacccatctt agcaacaaat gaaccataac catattcgcg caagcgctct
    28981 cggtattcgc gctctgtcat gatagacttg tgctcaagtg gtgtatcctt aggatcaatc
    29041 accacataag ccgcaaagta gataacttcc tcgagggcac gagggctcat atcaagggtc
    29101 aagcccatac ggcttggaat ccccttgaag taccagatgt gagatacagg agctttcaat
    29161 tcgatatgtc ccatacgctc acgacgaact ttcgtacgcg ttacttcaac cccacagcgg
    29221 tcacaaacaa ttcctctgta acgaatgcgt ttgtacttac cacaagcaca ttcccagtct
    29281 tttgtaggac caaagatcac ttcatcaaag agtccttcac gttctggttt caaggtacga
    29341 taattgattg tttcaggttt tttgacttct ccataagacc atgaacggac tttacttgga
    29401 gaagctaggg tgatttgcat acttttaaaa cgatttacat caaccactat ttcttccctt
    29461 tctattctaa gtgaactgct tattcttgtt cagcagcttc ttctgttgct tccgcttttg
    29521 ttgctttctc agcttcttca gcttcaaagg ctgctttagc ctcttgggct gctttttcgc
    29581 gggctttttc aaggtcatct acgtggatga catcttcgtc cattccttca tccaagtcgc
    29641 gaagttccac ttcttggtca tcttcgtcta ggacacgcat gtcaagacca agagattgca
    29701 attctttgac aagaactcgg aaggattctg gaacacctgg ttttggaatt ggtttgcctt
    29761 ttgtaatagc ttcataggct ttcaaacgtc cgttgatatc gtccgacttg taagtcaaga
    29821 tttcttgaag gacatttgac gcaccgtagg cttcaagagc ccaaacctcc atctcaccga
    29881 aacgttgtcc accaaactga gccttacctc cgagtggttg ttgggtaaca gttgagtatg
    29941 gtccgactga acgcgcgtgc aatttatcat caaccatgtg gtggagtttg atcatgtaca
    30001 tgactccgac agaaacacgg ttatcaaacg gttcaccagt acgtccatcg taaaggatcg
    30061 ttttggcatc gctatccata cctgcttctt taacagttga ccaaagatct tcagaacttg
    30121 ctccatcaaa gactggtgta gcgatgtgaa taccaagagt acgagctgcc ataccaaggt
    30181 gaagctccat aacctgaccg atattcatac gtgatggtac cccaagtggg ttcaacatga
    30241 tgtcgactgg agttccgtct ggaaggtaag gcatgtcttc tacaggaacg atacgagaga
    30301 caaccccttt gtttccgtga cgtccggcca ttttatctcc gaccttaatc ttacgttttt
    30361 gagcgatgta aacacgaacc aacatgttaa cacctgattg caactcatct ccatttacac
    30421 gtgtaaagat cttaacatca cgaacgacac catcggcacc gtgtggtaca cgaagagaag
    30481 tatcacgcac ttcacgagac ttgtctccaa agatagcgtg caagagacgt tcttcagctg
    30541 aaagatcttt ctcaccctta ggtgttactt tacctacaag aatatcacct tctttaacct
    30601 cagcaccaat acggataatc cccatttcgt caaggtcttt gagggcatct tcaccaacgt
    30661 ttggaatttc gcgagtgatt tcttcaggcc caagctttgt atcgcgcgtt tctgattcgt
    30721 attcttcaag gtgaacagat gtgtagacat cgtccttcac caagcgttcg ctcatgataa
    30781 cggcatcctc gaagttgtaa ccttcccaag tcatgtaggc aacgattggg ttttgtccaa
    30841 gcgccatttc tccattttcc atagaaggtc cgtcagcgat gaaatcgcct ttttcaacga
    30901 catcaccaac ttttacgaga gtgcgttggt tgtaagcagt acctgagttt gaacgacgga
    30961 atttttggat gtggtaaaca tccaatgaac catcttcacg acgaacttct accttgtcag
    31021 catctgcgta agtaacttta ccatcatact gagcaatcac agccgcacca gaatcgtggg
    31081 ctgcttggta ttccatacca gtaccaacgt aaggtgcctg aggattaatc aatggcacag
    31141 cctgacgttg catattggct cccatgaggg cacggttgga gtcatcgttt tccaagaaag
    31201 gaatacatgc tgtcgcaacg gcaactacct gttttggtga aacgtccatg tagtcaacaa
    31261 tattagctgg atactcttgg ttgacccctt ggtgacgtcc catgacaatc ttctcagcaa
    31321 aggttccatc ttcattcaga cgagagttag cctgagctac agtatattca tcttcttcat
    31381 cagctgtcaa ccaaacaatt tcgttcgtga caacacctgt ttcacggtca accttacggt
    31441 atggtgtttg aacaaaacca tatttgttca agtgtccata agatgacaag ttattgatca
    31501 aaccgatgtt aggtccttca ggtgtctcga ttggacacat acgaccatag tgagtgtagt
    31561 gcacgtcacg tacttcatat ccagcacggt cacgagtcaa accaccaggt cctaaggctg
    31621 acaaacggcg tttgtgagac aactcagaaa gcgggttgtg ttggtccatg aactgtgaca
    31681 actgtgatga accaaagaat tctttaactg cagctgttac aggacggata ttgataattt
    31741 gttgtggtgt caagacttca ttgtcctgaa cagacatacg ttcacggaca ttacgttcca
    31801 tacgagaaag tcccaaacgt acttggttgg caagcaattc accaaccgca cggatacgac
    31861 gatttccaag gtggtcgata tcatctacac ggccaagtcc ttcagccaag ttgaggaagt
    31921 agctcatctc agcaaggata tctgcaggag tcaccgtacg aaccttgtca tctgggttag
    31981 cattaccaat gatcgttacg acgcgatctg gatcagttgg agcaataacc ttgaattttt
    32041 gaagaacaac aggctcagtc acaacggctg catcgtttgg gatgtagaca atcttgttca
    32101 agtcgccatc caaatggctt tcaatgcttt caatcacgct acgagtcata atcgtaccag
    32161 cttctaccaa gatttctcca gtttcagggt ctaccaatgg ctctgcaatg gtttggttga
    32221 gcaaacgtgt tttaacattg agttttttat tgattttgta acgaccaact gctgccaagt
    32281 cataacgacg tgggtcaaag aagcgagcta caagcaagct acgtgagctt tcagccgtct
    32341 taggctcacc tggacgaagg cgttcgtaaa tttctttcaa ggcttcgtct gtacgagagt
    32401 ccattggatt cttgtggata tctttttcaa cagtgttgcg aaccaattcg ctgtctccaa
    32461 atatatcaaa gatttcatca tcacctgaga aaccaagagc acgaaccaag gttgtaaatg
    32521 gaatcttacg agtacggtcg atacgagtgt aggtgatatc ttttgagtcg ctttcaagtt
    32581 ccaaccaagc tccacggtta gggataacag ttgaaccata gcccacctta ccatttttgt
    32641 ctactttgtc gttaaagtaa acacctggtg agcggaccaa ctgagaaacg ataatacgtt
    32701 caccaccatt gatgatgaaa gtacccattt ctgtcatgat tgggaaatca ccaaagaaaa
    32761 cttcttgggt cttgatttcg cctgtttctt tattgatcaa acggaaggtt acaaaaattg
    32821 gtgctgagta gctagcatcg tggatacgag cttcttctag cgtgtatttt ggttccttga
    32881 tttcatatcc aacaaattcc aactccattg tgtctgtgaa gtttgaaatt ggcaatacat
    32941 cttcaaacac ttccttaaga ccgtggtcta ggaaagcttt gaatgagtca gtttgaattt
    33001 caatcaaatt tggtaagtca agaacttctt tgattcttga aaaactacga cgggtacgat
    33061 gtttcccgta ttgaacgtca tgtcctgcca agatgattct cctttgtaaa taagttccaa
    33121 gccttgtcaa tcaggctttt ctaatcgtca tatggttgta aaccccttat caccgtgtcc
    33181 tcttgacgaa ttttcagaat ctttaagcct ctgttacaaa tgctcataat cttgaaaaaa
    33241 agcacaaaaa gagcagctaa atctgacttt ttcagaagat ttaactgctg tgagccttgt
    33301 ctggacaata tttcagacaa aacctacgac aaatgattac ccatattata ccctatttag
    33361 ctagattttt caaggggttt cagtaggttt ttggtaaatt ttttcccata gaaaacttgg
    33421 catcacattc gaatcacgct atggtacaaa aaactgaaaa aactattgac tgaaaatcat
    33481 tttcaaggta taataataaa cgttaaggcg gtatagccaa gtggtaaggc acggctctgc
    33541 aaaagcttga tcgtcggttc aaatccgtct accgccttct ataacttgat ttatcaggtt
    33601 tcaaatgaac agaaagccca atttgaaggg ctttttttat tttccctcga ataaatacgt
    33661 ataactttaa aaacttttgg agcgagtttg tggcagagtt ctttccatgg cataattccc
    33721 ttttgaaatc aattgaaaaa agcttcgtca cgcctggtga caaaagcctc tagtttattc
    33781 tgtttcttct tctatttcga cttctgtgat ttggactttt accttggtaa cacgtccatt
    33841 cttcacttta tcattggtta agataaactg tttgttttgg ctgaccaatt catagctgag
    33901 tttctcagtc gttggaatgg ttcccactcc tgtcaaataa taaccagcga tggtatcaac
    33961 gtcatcactt tccagctcaa catcaaagta attattgaaa tcattgaggg tcatagttcc
    34021 ttgaacaatg taggtatcct cgccaatctg atgaacatct attgctgctt tgtccgtttc
    34081 atcatcaatt tcaccaacaa tttcctctaa gaggtcttcc aaagtcacta aaccagccat
    34141 accaccgtat tcatccagca agattgccat ttgtctttgg gtatttcgca gttcttttag
    34201 caagtcatcc acaaaaatag tttcaggtac aaaaagtgga tcttgtaaaa ttctcttcca
    34261 aacaatattg tcaaaaccgt ccacaaagcc tgccttaagg agactcttgg tgtgaatgat
    34321 tccaattaca ttgtccttat ccccatcata aaccgggata cgagaataat tttgttttaa
    34381 aatactttgg ataatggctt gactatcatc ctgaatatcc accataaagg catccgttcg
    34441 aggaaccata acctctcgtg ccatcagttc atcgagcgaa aagacacctt gtagcatctc
    34501 aatctcatca gcatccaatg tttcttcact atttgtcagc atataggcaa tttcatcacg
    34561 ggtcattttt tcatccgcat catcgaatga cataggagtc aaatggctca agaaattggt
    34621 cgaagcagct aaaagccaaa caaaaggact gactagtttt ccgatcccaa tgataatcgg
    34681 cgctgtacga attgccaagg catcctttag attaagagcg attctcttag gatataattc
    34741 cccaaaaacg atggaaatat aggtcaaaaa tgccaaggat agaaaagttg ccacggcttg
    34801 tgctgtttcg ccattcccaa gccaagaggc aatcacacgt cctagagtat tagttaaact
    34861 cgcccctgat aagattgtaa tcagggtgat tcctacctga atggttgata aaaagtggtt
    34921 aggattttct agtaccttca gcaggcggat gtagcgtctg tctccttctt ccgccttttg
    34981 ttcaactcgg gcacgattaa gagaaaccat ggccatttct gtggctgaga aaaaggcatt
    35041 taataccgtc aagataaaca ataaaacaaa ttgtagcaac aaattctgac tacttgggtc
    35101 ttccatagtt cttctcctaa aatagtatct tatcctttat tatatcacaa aatttaatcc
    35161 aatacatatt attttttctt accgtaactt ctcaaagtaa cttccatctc tctcccaaaa
    35221 ctggaagtta gttttagaag ttgctatttt ttcttagtac ctgttctagc cctgcttaaa
    35281 ctagtaaaaa gaactcctac atccataagt gacataggag tttaggctta tcttttactg
    35341 agttacagtt acttctccag ttcggtaatc cagttgaagt cccttttgaa cattgggaac
    35401 tagaacattg aattccaatt ctccatccga agacttggct tcaatctgtg aagctgaggg
    35461 aactaaatcc tcgtttgaag cgtagtaaag ggttacacgg taacggacac gcttgttttg
    35521 gtccaaggct ttacgcacct tgctttcata gtagttttga ccagtcgaat actcggcttg
    35581 tgcctgattt gcccaggctg tctgaacagc aatgttttta ggattgcttg ttgaggcatc
    35641 aaaaccatcc aaaccaccga ttaaggcata gcctaacaaa tgacctctat cgactgcatg
    35701 ggtataagag ccctttagat tcttgacctg atgccaacct ggaggagtcc aagaagttga
    35761 accattccca gtttctttac gattcttgta ctgacgagtg gccttagaca agagggcatt
    35821 agctacggtt ggaacagttt ccttgcccac tgtctttgtt ttattgtcag cgtagggctt
    35881 acttgaaacc ttggcatcta gatttgtttt attaccattg acgataaaag cacctgagcc
    35941 attccactcc agactcccct ttatttgact cttgactgcg tctgttaaga cactctctgc
    36001 caatgcttga ctaggagctt cagacgcttg ttttttctga ctaagattgg ttttgggact
    36061 attaggtgcc gacggcatct gcttgatata atagctccct gtagacaaaa gcaataacac
    36121 tagcagtccg attagtgtct gtcttgtttt tttgttcata tttctcctta tctttagaaa
    36181 aaggctggtt ctccagccta atttcctgta aatttatgaa tcaattcctg ccattttgct
    36241 ggagacagga tagcccatgg atcttgaccc ttgcccaaga ttccataacc taccattaaa
    36301 ccgattccta gagccagagt acctaaaatc agtactatga tgactaaaag taaacgcttg
    36361 actacgtagc ttgatttctt attcatcttc atcacttgcc tcaatccgct gaatcttagc
    36421 acctagctgc gccaacttct catggaaacc gtagtaacct ctatccaagt gaaccaattt
    36481 accgaccaca gtttctccct gtgctaccaa acctgtcaaa atcaaggctg cactggcacg
    36541 aaggtcagtt gaaagaactt ctgctccctg caaaggctgt ccaccaacaa tacgagctgt
    36601 atcacggata atctcagaat gcaagcccat gcggcgcatc tcttctaggt gttggaaacg
    36661 attttcgaaa actgtctcca ccatggttga ttcgcctttt gcaactgtca tcaaggctgt
    36721 aaattgagcc tgcatatctg ttggaaatcc tggatggggc aaggttttca catgaacagc
    36781 ttttagattt tctagttgag aacgaacacg aattccttcg tcttcttcaa ttacttcaac
    36841 acccatttca agtaacttgg caatcaaggg acggttgtgc tcccagacag cgtctcgaat
    36901 caagacatca ccaccagtca tggcagcagc taccataaag gttcctgctt cgatacggtc
    36961 ttggactaca ttgtgagtcg taccatgaag tttctcaaca ccagtaatgg ttatagtctc
    37021 tgtaccagca cctttgacct tggctcccat ttcattaagg agaatggcta agtcaacaat
    37081 ctcaggctca cgcgcagcat tctcaatcac tgtcacccca tcagccagag tcgctgccat
    37141 catcaagttc tgcgttgcac caacacttgg aaagtccata tagatatgag cgccatgcaa
    37201 gcgttctgcc ttggcttcga tgtaaccagc tgtctgacta atcttaaccc ccatagcttc
    37261 cagacctttc aaatgaagat caataggacg actaccaatc gtacaaccac ctggcatgga
    37321 taccttggta tgacccacac gggcaaggat tggccctaat acaacgatgg aggcgcgcat
    37381 cttgctgaca tacttgtaag gggcttcctc agtgatgtcg ccagtagcat ccaccttgac
    37441 aagatgagct tcctcatcaa agtcaacctt ggcattcaaa ccaccaacta cctgattcat
    37501 aataaagaca tccgacaaaa tcggaacatt ctgcaagacg gtctttcctt cacttgctag
    37561 aatagtcgct gccaacaagg gtaagactgc attttttgct ccctcgatcg tcacgcttcc
    37621 taccagacga ttatcgccac cttgaaccac aattttatcc atactcgttt cctttactct
    37681 tgattttata ataatcctct aagcgcttct tgccacaaat gatacaggct aataaagaaa
    37741 gaactcagga tgtagcctat gacaatgcta aaaaaggcta ctaataaacg aacttttctt
    37801 gtattctcat ctgtcacttt taaaaccttc tcccatctaa caagatcctt taaaaggtaa
    37861 aaactcacat aaataaagag catatgacta cttagagtga ataataattg aatcatttga
    37921 ctattatacc atcttctctg tttgtgcgct agtttggaaa cttcactcaa aaattaggga
    37981 ttgtttttca agtaatcaat cgcatcttgt agggttttaa cgggcacgat tttcatatcc
    38041 gtcttgattg ttttagccgc ttctagggct gtttggtagt tgtttttcgc gtccggatgc
    38101 gccttttgtt cttcttcgct aacagggtta tcaggagtaa agaaaatagc agcacctgcc
    38161 ctagccgaag ctacaacctt cttatcaata cctccaatgt ctcccacatt accatcgcgg
    38221 tcaatggtac ctgtaccggc aacaatacga ccattacgaa gatctgggtg agctatttga
    38281 gtatagatag ctagactaaa catgagacca gcacttggac cgccaatacc agctgttgaa
    38341 aagctaattg ggacattgct gattacctct gtacggtcaa tcaagccgat tccaattcca
    38401 tttttgccat tttccaaggt gatgattttt ccttctgcag acttggtttg cccatcctct
    38461 tcataggtga ccttgacgga atcccctaat ttttgagaac tgacgtaatc aatcaagtct
    38521 ttggaactat caaaggtctg atcattgact gctgtgactg tatcagagat attgagaatc
    38581 cctttaaagg ttgaattatc cgtcacattc aaaacataaa ctccaaagta cttgagttcg
    38641 atatccttac cagctgtttt tagtccttga tacttggcca tattttgcga tgtttgcatg
    38701 tagaattgat tgattcgcat aaattcaaca tcggaagaac cacctgtagt ctcctgagca
    38761 ctacgaatat ctgtaaaagg tgtcaaccaa gcataaatca tatgagctaa agtggcatgt
    38821 tgaacaccaa ccgtaacgaa ttgataggca ccagcttcct tatcttctgt gtcatttact
    38881 ttaaggactt ggcgaatatc ttccgaacca cctggaacct ctatataata aggcaagggc
    38941 actacaaatg ccaagaaagt cacaatcaag gccgcaatga cgtataaggg ccatctaatc
    39001 ttttttttca tttcttattt cctccaaaat actctcggga acatagcagg caatatcctg
    39061 accaaacttc aaaagctctc taacgcctga tgaactgata tagagatgtt caggtcgact
    39121 atgtaaataa atagtctcta tatcagaaga cagctgatga ttgtagtaat caaaactggc
    39181 ttcatattgc aaatccgacg catttctcaa gcctcgcact agacaagtag cacccaatct
    39241 ttttgcaaca tcgaccacca attcatcatg agaagacacg actttaacat ttcccaaatg
    39301 tttcacagcc ttttctaacc cccgtttacg attttcaaga gggagaaatc cttgtttgtg
    39361 gggattaaaa aaaataccca cataaagctt atcaaagagt ctgctcgccc gttcaatcat
    39421 atccagatgc ccatttgtca tcggatcaaa tgagcctgtg aataagccaa tcttatctga
    39481 catagactgt caccttacta attccataaa tcttttcctt ccagataccc agacaggcaa
    39541 tctcttctgg aagttcaacg gccttatccg tctcgcacac aaccataaca tcttcagaaa
    39601 aaagctctct ctcagccatt ttttcaatat ctgctacgat ttgttccttg gcatagggag
    39661 ggtctaagaa aacgaggtca aattccccag atacctgttc caatgccctc tctgcatcca
    39721 tcttgaggag ttgaaatttt ccaacttcct tggtcatctg gatattttca gccacgatgg
    39781 tctgagcctt acggtctcgc tccaccaaaa cagcactgga catgccacgc gatactgctt
    39841 cgatagataa accaccacta cctgcataaa ggtccaagac tcgtccccct tcaaagtagg
    39901 gaccaatcat gttaaaaatg gctcccctaa ccttatccga agtaggtctt gtcgtcttgc
    39961 cttctagtgt cttgagggga cgtcccccat agattcctga tacgattttc atactgttta
    40021 ttataccaaa ttatagacaa aaagagaaag aaaaccgaac cttgcggttc gattctctac
    40081 aaaatatttt cgtaagtatc gcggacttct tgaggccaaa cacttgtttg cacttctccg
    40141 atgtgtctct tgcgaagtag gaacatggcc atacgagatt gtccaattcc tccaccgatt
    40201 gtcaatggga atagaccatt caacaaagac ttgtgccatt ccaattccaa gcggtcttca
    40261 tcacctgtaa tttccacctg acgtctaaga gtttcttcat ctacacgaat tcccatagaa
    40321 gacaactcaa aggctccacc taaagactca ttccagacaa gaatatcacc atttagaccc
    40381 ttgtagccat tctcagactc gcttgtccag tcatcatagt ctggtgcacg tccatcgtgc
    40441 ggtttaccat ctggcaactc gccaccgata ccaatcaaaa agacggctcc aaattcttta
    40501 caaatcgcat tttcacgttc tttcggtgtc aagtctgggt agcgttctac caattcttct
    40561 gtatggataa aggtgatttg ttttggcaag atagactcga tgtcatagcg ggcttcaaca
    40621 gctagctcag tcagacgaat agccttataa atcttctcaa ctgtttcttt tagataaacg
    40681 atgttacgct taccatttgg gataaccttc tcccagtccc actggtcaac ataaacagag
    40741 tgggttgcat ccaaggaatc ctcatctgga cgaagggctt tcatgtggac aaagagaccc
    40801 tctccttcac caaagccaaa acgagccaag gtgtggcgtt tccatttagc aagtgagtgc
    40861 accacttcat aagtagcatc agggatttgg agaaccttga ccgatactgg attttccaca
    40921 ccagacaggt tgtcctgcat tccgtcaccg accttactca agataggacc ttgaacttcg
    40981 acaacttcta gcttatcttt caaatactgg gtaaaagtgt ttttgacaaa ggaaatttct
    41041 tcttgttgat ggataaaact tttcttcata gacaactcct caaaaattta ataaacgtat
    41101 tatacaccta tttccaagaa aagaaaagag aaaatttaaa aaaaatcagt gtcactcaaa
    41161 acactgattt catagacctt ttagtcattg cgaccaaaga tacgtagaat acttaggaaa
    41221 agattgataa aatcaagata gatgctgaga gccattgaca ccacccagcc tgtcgctaca
    41281 cgaccttgtg attgttcata ggcgaggcga atcttttggt tatcccaagc aatcaaccct
    41341 gaaaaaacca aaaccatggc tacgctaatc atataatcaa agaagccact agccaagaaa
    41401 atattgacta ccatagcaat cagtaaacca atgagagctg ccatcattgc tcgaccaatc
    41461 ccactcaagt ctttcttggt aaaaatacca actgccgcca tgacaaagaa gagaagggcg
    41521 ctcgatacaa aggcagataa aactgtaccc ggagtataga aagccaccac aaaactaagg
    41581 gtaaagccgt ttaaaacgga gtaaagtaaa aatactggaa gagcagctgg actatttctt
    41641 gaagccatgc tactggcaac gaaaaccaaa gccaactccg caaaagtagc aatggtcaac
    41701 cagagacgcc cctgcatcaa aaagtaaacc aactgagact gaaagaccgt caacataagg
    41761 cctgatacca aagcagatag tccgattccc agaccaacaa aggcataaac cttagcgtaa
    41821 aattgattga gacctgcacg gtcatgtata atagtgtgat tcatccattt ctccttttct
    41881 gtgaacatct ttccttgatt ataacaaaaa aagttaaaat tagcttaaat ggaagattaa
    41941 aataccggct gcaaccgcaa cattcaaact ctcggcctgc cccttcatgc taatatggac
    42001 caactggtct gcactttcag ccataagggg actaattcct tgaccctcat ttcccataac
    42061 tagtacaaaa ttttctatag aaggcagttc tctgtaatca acagaatctt tagatagggt
    42121 tgttgctagc actgggatag ctaccttttt agtttcgtca agaagcgctt gactagtcat
    42181 ccggtaaatg ggcagatgga aatgactacc ttgcatggaa cgtagggttt tgagactgta
    42241 gatgtctgcc gacttatctg aaacaatcac tcctgtaaaa cctgctgcat ccgcagttcg
    42301 aatgatagtt cctacattac caggatcttg cacatcttcc aaaaacaaga acttgccctg
    42361 actcaaatca gcttgtccta cttcttcttt ttgaaccacg gcaacaattc cctgtggagt
    42421 ctgagaatcc gccaaatcta gcaaaatatc ctctgacacc cagacagttt gcgaaaaagt
    42481 agctaactga tctcgataat tttctagggc aaagattttc tcaatcgtca ctccagcttg
    42541 gacagcttct tcaaacaagt gccagccttc aatcaagtag gcagacttgc ggtatttttt
    42601 ttggcgtaat ttcttggcat tttttaccac agaattggct tttgaggtta taatagtcat
    42661 agaaatatta taacacaatc aaaggggttt ggtatgcaaa aggttagaat gattgcccaa
    42721 ggtagggtac agggagtcgg ctttcgttgg ggtgtttaca gcttggcact tgaaattggt
    42781 ggcatcacag gtcgagtatg gaataacgac gatggcacag tggaaatctt agcccaagca
    42841 gactcatctg ctatcatggc aaaatttatc caagaaatcc gaaaaggacc gacacctttt
    42901 tcaaaagtaa gctacttaga tgtcaaacta agcaactttc ctccctactc tgactttaaa
    42961 atcgcaaatt aggtctccag aactattgta tattttgtaa aaaaacagta gaatagaaag
    43021 gtataatttt taaagaagga ataaaaacag tgaaatctat taaacgtttt gcactctcag
    43081 ctatgggagc ggctatgttg cttgtcttga ctggttgtgt caatgtcgat aaaaccacag
    43141 gtcagccaac aggatttatt tggaatacca tcggagcccc tatggctgaa gctatcaagt
    43201 acttcgctac tgataaaggt ctaggctttg gtgtcgctat catcatcgta accattatcg
    43261 tgcgcttgat tatcttgcca cttggtatct accaatcatg gaaggcaacg cttcactctg
    43321 aaaagatgaa cgccctcaag cacgtccttg agccacacca aacgcgtctc aaagaagcga
    43381 ctactcaaga agaaaaactc gaagcccaac aagctctctt tgctgctcaa aaagagcacg
    43441 gtatcagcat gtttggcggt gtaggatgtt tccctatcct ccttcaaatg cctttcttct
    43501 ctgctatcta ctttgctgcc caacatactg aaggggttgc tcaagcaagc tacctaggca
    43561 ttcctctagg ttctccaagt atgattttgg ttgcctgtgc tggtgtcctt tactatcttc
    43621 aatcgctcct ttcacttcac ggagtagaag atgaaatgca aagagaacaa atcaagaaaa
    43681 tgatttacat gagcccactc atgatcgtcg tcttctccct cttctcacca gctagtgtca
    43741 cactttactg ggttgtcggt ggtttcatga tgattctcca acagtttatc gtcaactata
    43801 tcgttcgtcc aaaacttcgc aaaaaagtcc gtgaagaact agccaagaac ccaccaaaag
    43861 caagtgcttt ctctaaacca agtggacgaa aagacgttac ccctgaacaa ccaactgcta
    43921 tcacaagcaa gaaaaaacac aaaaatcgca acgctggaaa acaacgttcg agataagaag
    43981 aaaaaggctt agctgatttg ctaagtcttt ttgcaaatca aaagcccgat gtttccatca
    44041 ggcttctttt ctatccatgt acacgtttca tataatcttg ataactttcg gtatccatga
    44101 gttttttagc gttcttgacg cgatctgctg ttggtggttt gactccttcg agggaatatg
    44161 gaattccaag ttcacgccac ttgaactcac ccatggtgtg ataaggtaga atttcaaact
    44221 tatcaacatt tttgagggtc ttgacgaact taccaagttc aatcaagtca tcatctctgt
    44281 ctgtcaatcc tggaactagc acgtggcgaa tccagacagg ttttccaata tctgatagat
    44341 actgggcaca agccaagata tttttattgg tttgtctagt gacaatcttg tgctgttctt
    44401 cgttgatttc cttgatatcc aaaagaacca agtcagtgac agccatgagt ttgtcaaact
    44461 tctcaaggta acgtggttta ttacggaaag gaagagcaca ggtatccaag gtacagtgga
    44521 ttccttgttc cttagccttg gtgaagagag caatcaggaa atcaatctgc aagagagctt
    44581 ctcctccact gactgtaatc ccacccttat ttccccagaa accacggtag cgcaaggcct
    44641 ctgtcaagac atcatctacc gtccgttcac gtgacttatt ggactccata gcccaagtgt
    44701 ctgggttgtg gcaatactgg caacgcatgt gacagccctg caaaaagaca ataaagcgaa
    44761 taccaggccc atctactgac ccaaagcttt ctgtcgaatg caccattcct gtcacttgtc
    44821 cataatcaat tgtttcttca gacatatcgt taccttcctt gaaaacgttt tatagtttta
    44881 ttatatcacg acttgaagga aaaacaagat ttttgcctat tttttagaaa gcaatctgtt
    44941 tttcaatttc attttcaatc tattatcaga ttattcttca aaatcgaagc catataaggt
    45001 tgcaaaatag tcctcagggc gctctgcacg gcggatttga cgggctttac cttcttcggt
    45061 atagaggatt tccgcagaac gtaatttggc attatactgg tagcccattg aaaatccgtg
    45121 ggcacctgta tcatgaatta ccagcaaatc accgatttct gtatgaggca gttcgcgatt
    45181 gactgcaaat ttatcattgt tttcacagag tgaaccaacc acatctaccg cttcagctgg
    45241 tccatctgga tgggtcacgt tgctaatatg atggtaagct ccgtacatag ctggacgcat
    45301 gaggttgact gctgaggcat ccacacctag ataggtacgg taggtttcct tcttatgagt
    45361 cactcttgtg actagagcac cgtgaggtgc cagcataaaa cgacccaatt cggtgaaaat
    45421 cttgacctga ccaagacctg ctgacgtaag aacttcttca tacaccttac gaactccctc
    45481 accaatcaag gcgatatcgt tcggctcctg gtctggacga taattaacac caataccgcc
    45541 agaaagattg ataaagtcta gccaaatgcc caacttttcc ttgatttcaa cagccagttc
    45601 aaagagctga cgagccaact ctggataata gagatgggtc acggtattgg acgctaggaa
    45661 ggagtgaatc ccaaaagtct tggctccttt ttccttcaag atagcaaagg cttcaaagag
    45721 ctggtccttg gtcatgccaa acttagcctc cccaggattg tccataatgt ctgtccccag
    45781 ttcaaaaacg cctccaggat tataacgaca agagatgatt tctggaatgc ctgctactct
    45841 ctccagatgt tcaatatctt caaaggcatc caagttaatg gtcgcaccca attcacgtgc
    45901 ataggcgtat tccttgtctg gcgtgttgtt ggaagagaac ataatctcag aacccagaaa
    45961 gtccagttta tggctcatca aaagctctac ataactagag cagtccacac cacaaccttc
    46021 ttcttggaga attttcaaaa tagctggagt tggagtagcc ttaactgcaa aatattcctt
    46081 aaagcccttg ttccacgaaa aagcttggtt gacggctctt gccttctcac gaatcccctt
    46141 ctcatcatac aagtgaaagg gagtcgggaa ctcggcaaca atcgcttcta actcttctct
    46201 attgataaat ggtgttttca taagcttcct tctattctgt ttgcaaagaa aggctgggac
    46261 aatcgttcca acctttagtt ctatctctta tttatcttcg tcaaagatat tgccaacctc
    46321 aacatcgatg gcttggttct tgacatcaat attagttacc ttcaagagtg acttgtagtc
    46381 aaactgcttt tcacgttctt cttgggcatt gtccgcaaag accgctacac ctgccagttc
    46441 tgagtcgaac tcgcgcaaga gactaatcat accgttgacc gttccgccac ctttcaagaa
    46501 gtcatccaca atcaagacac ggctacctgc cttaagacta cgttttgaaa ggaacatttt
    46561 ctcgatacgg tcaccacttg aacctgaaac atagttgacg ctaacagttg aaccttcggt
    46621 aattttcagg tcacggcgca caatgacaaa agagacattg aggacattgg caactgcatt
    46681 tgcaagtggc acacccttag ttgctacggt cataaccgcg tcaatttttt ggtccataaa
    46741 gcttttggca ataatacgac caatattttt caagatggct ggtgtgctaa gcaaatcaga
    46801 cagatagata taaccacctg gcaagatacg gtcactttct gacaacttgg tacgcaagtc
    46861 ttcaaccatt tccttagcat cctgactcga aatagacggt gtgaagatga cacctccgcc
    46921 agccccagtc actgtctgga tatgaccgat ttcaatttcc tcaaaggcgc gtttgataat
    46981 gacgatatct tctgagatgg atgatttagc agactcatac ttttcagcaa aagtattgag
    47041 actagttagt ttataaggat tattaatcaa atagttggaa atgacaacca tccgatcact
    47101 tcttcttaat ttcatttcta tttcctattc catttttatt caaaaaatca aaaagcaaac
    47161 tagaaagctg gtcgctagtg gttcaaaaca ctgttttgag attgtcaata gaactgacaa
    47221 accctgtaat atacctgcat atatacatac gacaaggcga tactacccta gtttgaagag
    47281 attttcgaag agtattcatt tttgtctttt acttattata ccatattcac ataaaaaaac
    47341 gaacattctt atcctaaaaa atgctcattt ttcttaaatt atcaatctaa atctggttta
    47401 tagaaggaac gattatccat agcgaagatt ttattggaca tctctccttt atccaccaaa
    47461 gccagagctg ttgacatcat catcatgctt gcatccagat tgtcaatcat atggataatc
    47521 tctgcctcca taatacgtgg acggactgga cttccatatt caagcaagcc gtggtgactg
    47581 aggatgacat gacgaagcaa aacgacttct tccttggtat catcgatgcc gagttccata
    47641 actgtcttgg taatttcgct atcaatgaga gcgatatgtc caagaagatt acctcgcact
    47701 gtgtactctg tctggtctgg ccccgtcaac tcgatgacct tagccaagtc atgcagcata
    47761 atccccgcat agagcaggct cttattgagc tgaggataaa cttcgctaat agcgtctgcc
    47821 aaacgcacca tggtcgccgt atgataggcc aagcccgttt caaaggcatg gtggttggtc
    47881 ttggcagctg gataggagta gaattcctta tcatacttgg tgtagagatt tcggacaatc
    47941 cgttgccaga caggattttc aattttgaaa atcatttgcg acatgtagtc acgaatttcc
    48001 ttgacatcaa ctggtgactt gaccttgaaa tcagctgggt cattgggttc accagcttga
    48061 ggcaggcgga gagtaatttg attgacttga ggggtattgt tataaacttc tcggcgtcct
    48121 ttcatgtgga caaccttacc tgcggtaaag gcctcaatgt tatgaggttg ggcatcccag
    48181 agcttcccat caatctcgcc actatcatct tggaaggtaa aggctaggta gtttttccca
    48241 gctcgagttt gcctcaggtc agctgatttg attaggtaaa agccttcaaa taactcatct
    48301 tttttcatgt gactaatctt catattcttc ctcattttct tgaaaatgga gtagatcaag
    48361 cgcaggctca ccttctgaca actcaatgtg acggagcgtc cgctcgatag ctatggtacg
    48421 acggtttaat aattcatcaa tattgccaga ggcatgttgg agatgttttt gtgccttgac
    48481 cagaatacca ccaaacttgc caaactcggt cttgacactg gcaagagtct tgctgatatg
    48541 gtcggcactc ttttggatat taagggtctt gaaaccaact gatagggagt taagaagggc
    48601 tgatagggta cttggtcctg caacaataat ctgttcttcc cgtctcaaat catcaaagaa
    48661 gaccggattg cggacgattt ctgagtagag accttctgtc ggaacaaaca aaactccaaa
    48721 attggtcgtc cgaggtggtg ctatgtactt gttcctaata tccctagcaa agcgcttgac
    48781 gcttgctagg agtgacttac gacagcgttc aatctcatcc ttgtcacctg tctcataggc
    48841 ttcttccaag cggtaataat ctgccagtgg aaacttagag tcaattggca gatagacgta
    48901 ttcttggtcg ccttgtccgg gtaacttgat ggcatactcc actcgttcac tagagttttc
    48961 aaccgttgcg tattctcgtt cgtactgggc aggtgtcatg atgtcttcaa taatttgccc
    49021 cagttgcaat tctcccagaa tccctcgcgt cttggttcca gagagaacct tgttaagagc
    49081 tccgacatca cgggcaactg tctgcatttc tccaaggcca cgattgacag actccagttg
    49141 tttagaaact gtctcaaagg aagcctgtaa gcgtgtctgc aaggtctttt ctagtttttc
    49201 ctcgaccgtc tggcgcattt gttccaaacg ttgctcattt gattcctgca aggcttggag
    49261 acgttggtct gtcttgtctc tagtttggag gagattatct gtcatttctt gacggacttg
    49321 ggtcagacct tggtgcaatt caatccgcac ttcttgcaaa cggtcgctga caaccacttc
    49381 caaatctttt tggtctaact ggctggcttg tctggcttgg tcaaagcggt aatccaactg
    49441 gtctgacaaa tgatctgcct gatcctccaa gctcttactt aagtgtttct cctgcctatc
    49501 ctgcctttgc caaatcagaa agagaccagc tagattggca attaataata gaataagtaa
    49561 actttccatc ctacctcctg tccttgctat gcagtacgac cacataacca tctgggcaag
    49621 ttaccgacac ttccctatct atatattcgt tagaagcgta cactttttta aagaaaaaat
    49681 tttcctctgt caactcatac ttggctccaa gaatagtcag ctggctatcc cgaactggca
    49741 taaaggctag atagtcgtag tctgaacgag gttctagctg actgattcct tctggacaat
    49801 aagtaatcaa gttttgccca tcctcaattt ctatttgatg catatagggt gccaacttag
    49861 gattgctagg cagaaagaca ttggccaaca tatggtcaat acggccaccc aaggcaccga
    49921 aaatagtgac ctgagcctga ggattttgtt caaagatggt taagagagcc aattccagat
    49981 ctgtatcatc cttttctggt cgtgcttgga caaaatactg ggcacctttt tgaatcacct
    50041 gtcgctcttc ttccgtcaca gaatcaaaat ctccgactgc tagagcaaga ggtaagtctt
    50101 cttccaagac ccagagcgag cctcgatcca ccccaacaaa agcatcaaaa tctgtccgat
    50161 aatgaccgcg gtttccgcct gcaaaaactg caaccctagt ccagttgttt tctgagagtt
    50221 tgtactcgct cattgacttc tcccttaaag acataggaac ctgctacaaa aacagtcgca
    50281 ccggcttctt tggcttgagc aatagtttgg tcatcaatcc caccatccac ttcgatttca
    50341 aagttcaaac ctttttcctc acgaagagca accaactcac ggaccttatc catggtttct
    50401 ggcagaaagg cttgcccacc aaaacctgga ttaaccgtca tgactaaaac ttggtcaact
    50461 agatgaagga cgtgcttgat ggcttcaact gatgtgccag gattgataac gactgaaggc
    50521 ttaactccga gtgaacgaat tttttggagg gcgccatgaa tatgaggcgt tgcttctaca
    50581 tggatactga tgatgtctgc acctgcacgc gcaaaatctt ccagatgatg ctcagggttt
    50641 gacaccatca agtggcaatc gaaaaccatc ttactatgag gacgaaggct ctcgaccaca
    50701 cctgcaccaa aactgatttg cggtacaaaa tgactgtcca tgatatcgat atgggcatat
    50761 tctgccccag ttgcttctag acgtttgatt tcacgttcaa agttggcata atctgctgcc
    50821 agaattgacg gagcaatctt gtattgagac ataggtttct ccttattttg gaattttttt
    50881 gctgactttt ttataggttt ctctacgatt ttcaatttca ctaaggaatt gcaggtaatt
    50941 gtcaaaacgg aaggttgcaa taacaccctc ttcaacagct ggtttgacgg cacaagacgg
    51001 ctcatgggta tgggtacaag tacggaactt acaatctcgg ctaacagtag caatctctgg
    51061 gaaagcctga ttgaggtctt cagcccttga tacttcatag tccaaggatg aaaatcctgg
    51121 tgtatctgcg attttacccc cgttgagatt gtaaaaacta acagctcgag tggtatggcg
    51181 accgcgacct agactgtctg aaatttctcc cgtttcaaga ttgaggtctg gtgcgatttt
    51241 attgagaaga gttgacttcc caacacctgt ctgccccata aagaccgtaa ccttgcctgt
    51301 taacaaagac aggagttcct ctttactggt cacaaagtca tagccgatgt caccataggt
    51361 ctgctggtaa aaatccagtt ctcccctatc ttccaacaaa tccattttgg aaatatagac
    51421 aatgggatgg atgcccttgt gctccaaaag aaccaagaaa cgatccagca aattgctgtt
    51481 aaaatcaggt tccttgacgg acatgattac tacagcttga tcgatattga caataggcgg
    51541 acgaaccaga ctgtttttcc gttcgtgaat tttgaggata tagccttctg aattttcctc
    51601 ggcagagaaa tctacccagt ccccaacata aggggtatgg ccttttttac ggaaattccc
    51661 acgcgcgcgt gtttgataaa cctggccatc actctccaca tagtagaaac ctgccaaggc
    51721 tttaatgatt tgtccctgca tcttagagtc cttgcccttt aagtgcgtct gctagaccgg
    51781 caaattctgc caagctgaga gcttccccac gcacacttgg tgacaagcct gcctggtcca
    51841 aagccttggt cagcttgtcc ttgacctctt cagtcttacc aaagtaacct gtcaagttat
    51901 tccacaaggt cttgcggcga tgggtaaaac tagccttgga aaccttaaag aaaaagttct
    51961 catcttctac tgctacggct ggctctggac gacgcaccat tttcaagatg gctgaatcca
    52021 catttggcgc tggcacaaag accgtacgag gcacgataaa ggcaaccttg gctgtcatgt
    52081 aatactgcac ggcgatagac aagctaccgt aagccttggt gttaggctgg gctgaaatgc
    52141 ggtccgctac ttctttctgc atcatgacca caaactcaca aaaaggaatg ccactctcaa
    52201 tcaagtgcat gagaataggc gtcgtgatgt agtaaggcaa attagccact accttgattg
    52261 gcaggtcagg atttttaaaa ttctggatat gttgcgccaa atcaaccttg agaatatctt
    52321 cgttaactac ggtcacatta tcaaaatcac gcagggtatc tgccaaaatt ggcaccaaac
    52381 ggtggtcaat ctcaaaagcc atgacttggg ctgcacgctc agccaaaaat tctgtcaagg
    52441 caccaatacc tggcccgatt tcgatgacat tgacctgatc atcaatttca gccgtatcca
    52501 caattttttg aaggatattg gtatccgtca aaaaattttg cccaaaggac tttttaaagg
    52561 taaaaccgtg acgctccagc actgccttgg tcacgctata atctgcaatt ctcatctatt
    52621 ctcttttcta ttatctgtta ctactattgt aacacattcc ccttgtattt tgggaatgaa
    52681 aatcatacca aaaaactatc tttcctcatg aagaaagata gtcttggaaa tctttaaaag
    52741 tggccttagc agttctctcg aaacatgcgt tcaaaaaaat cagcttcttg ataacttcga
    52801 ttttcaggta gggtcaaatc cacatcctcc tccacatcat ccactgtcag ttcaaccatc
    52861 tgaggtaaat ttttcaaacg ataatgcttt tgcctttgcc cttcaatact agcaaaatca
    52921 agcaaatagc catgcactcg gatttgaacc aaaaggagat gattggtcat attttccatg
    52981 atgaggatat cttctaaacc acctctggca ctaggataat cagataccct gcgaatacgg
    53041 attttttcac acatgagcaa gtttcctcat atcaatgatt tcatcagcct tattccagac
    53101 taggggatta tgggtcgcaa tgatgataat tcgattttca tctttcaaat ccaccaagag
    53161 attcataacc tcctctgaat tttcaggatc aagagctgct gttggttcat ctgccaaaat
    53221 caagggtgga tttttcaaaa tagtcttagc aagggcaact cgttgggcct ctcccccaga
    53281 taaagtatag attttttgtt ctaaatccaa ataccctaga ttaacttttt ctaaagcccc
    53341 cacttgcctt tccaaacgtt ctacttttga gattttctga ccaacaaaac ccaaatccaa
    53401 attttctttg attgattggt tttctaagag gccgaaattt tgaaagagat agcccatctg
    53461 gtctcgaaaa tactcacgag tgggaatggt ttttaaatct ttcccctgat agagaaccct
    53521 tccaccatct atcttttcta gctttcccaa gatattcagc agcgtcgtct ttccgcttcc
    53581 actctttccg attaaggcat aaaccttgcc cttctccagc ttgagattca aaccagagaa
    53641 aatcgcgcgg tcattaaatt tcttttccaa tccttgaata tcaatcatct tattttcctt
    53701 tcaatactgc catgctacca gcttcttctt ttttgtcctg ccttactaaa atcaagaggg
    53761 cgttaagcgt aaacaaagct acaactagag cgctaatcaa accatctctt gtcaaaatac
    53821 tagataggac taggccaagc aagagaactc ctccttgcgc cagtaaatac ttgccatgaa
    53881 gctcatagat tgtcatacca gcaagacgtt taatcataag ttcccgtctg aactgctcaa
    53941 aatagagaag attcatggaa tcaaataaca agatagccgt agacagggtc aaaatcgtcc
    54001 caataaggag agagtaaaac tccacccgtt tgtcatttag taccttggca aaaaatagct
    54061 ggctttttac caagtaagaa accttgtgat acagaccttt ctcttttaga gctgtgatgc
    54121 tgtctccata tcgatctagt ttcaaggcac tattagccgt agttccccac aacatccctg
    54181 caacaggtct tgttccagtc gcttgcggcg ttagaactac aataatcgga tcttttaggt
    54241 actggcgtgt tgtcttgtac ccatcattat agaggaaacg ttcctgtcct gtttctgtaa
    54301 aagctagcct tacctgtggg aggtagtgtt tctgactcgt cacttctaca ctttcagatg
    54361 aaaagttttg caggtaatct gtaaacaatc cttggtagta gacagactgc tctcgcaagc
    54421 tctcaggcaa gatcagccca aactctccct cagacaagtt ttgcatcttg tccataaact
    54481 ctgaagaaac ggtaatcttt tcttctatca gatagcgtgg tgagacatag ataacattcc
    54541 ctgacggtgt gtagtcactg agacgattgc catctaggtc cacttctgct ccatctgaga
    54601 aattgtcaac attgctcata atataaaaag agtctgtatt ggctaaccgt tcttcagtaa
    54661 atgtctgcca ctcacgatta tccttacgcg ttccttcttc atcggcaaat gcactagacc
    54721 aaccaaagga tagacggtaa cggtctgagg actggctcca tttattgcta gctctctcca
    54781 tttcctgcat ttcacggtag tggggtagga gagctgtcgc actcgatccg accaccaata
    54841 cagctaagag ttgccccacc atcatcaatg tcattatacg tttgagaggg agtttccctt
    54901 tcaatagatc caccagacta ttttcctgta aaccaagtag atagacgaca cttagtaagg
    54961 tagaaatccc tgccagggtc aatccataaa gtagaagagc aatgatgacc agttgcaccg
    55021 ttgccataaa caaggcacct tgataccaga gaatccccaa tcccaaaaga ctggatacca
    55081 gcactgagca gataagctgt ctcacatctt ctaacactgg tctgagagca actccaaaca
    55141 agctctcacc agctattaag cgaatccctg cctgacgaag ggatttgatc cgataaatca
    55201 gggtcagact cataaaggtc agcagaaaaa tagctaaact cagtagcacc ataggggtgg
    55261 ccgtcaatag taagactatc gaaaatggat cttctccatt cgaaacaaag ccttgataac
    55321 caagctcttt caaggtggtc tgtaagctca ctccatccaa acttcctgat acaatcaagt
    55381 aagaccctaa taaatcactc gtttctgcac tctccttgga ggaaatggtc agaccttctg
    55441 gaagctttcc ctcaccataa gtggcatagg taaagcgtgt ttctccagct tcatttggct
    55501 caacgattcg acgagcaatg agactattgt gctctaccgc caagtgactc aaagcctctg
    55561 tcacctcttc gcgactagct actggttgat ttatcatcat tcctgtcaca tcaacagaag
    55621 gatagttacc aaataaaatc tcttctcgat ggtcaacgga agttatcacc atataaagcg
    55681 atactaatac cattgaaatc aaaataaata aacgtttcat catttcctcc aaaaagttac
    55741 ttggtcactt agtgagaagg tgaccaagta aagctaaaca atagggctat accattctaa
    55801 acattatagt agaatgcaac tttctctccc caagaagtac gaatccacgc acgagaagtc
    55861 cctccagcac cagcatatcc cttgtcagat gaaccagttt ttctgctaac aactgttgaa
    55921 ctatggtatt ttgaagggtg atagtagttt gagtaagcac caccgttacc tgaaccataa
    55981 gtccaaacac caccttctgg gtattgaacg gctgcagagg caactgatac acctccacct
    56041 aatgttgctg caatgctcgc tacaagagct aactttttaa ctgtttgttt catattgata
    56101 ctcctctatt tttgattaca agattgttga gttacttgct cctctttcca ttatcaacgt
    56161 tgatactatt atattaccaa atgatattct aaaattattt gtttttctct aaattgtcaa
    56221 aatagcaccc tgaaatgaac ttttatagtc attatactcc atctttatca cactatcaag
    56281 gacatcaatg tccttaaaat ctaactattt catattattt ttagcttata tctaaaaaaa
    56341 cagttctaaa gacgaacttt agaactgttt tgatacgagg acaaggacat ttttgtcact
    56401 gattcactat gtttataaat attttttgac atcctcttgc cattcctctg tcaatttctt
    56461 tactagaaat ccatctccaa ttagcttcgc aaatgtttta gaagactgat aaaatgattc
    56521 agctaaacta aaatctcttt ctactcttaa tgcttgcttc cacaaaaaca taaatacaag
    56581 aggtttcttt tgataatctt gagttttatc cataatttct tgtaaacacg atagataatc
    56641 attaaaacaa tcagttactc ctaccttttc aagacaacac attcctgaaa taagagtatc
    56701 tctaattata aagtaattct ctatttgagt taccttcttc tgttccaaaa gaaagagcat
    56761 tagcttttcg atttgattta taaatttggc aagatctttt ctaatgagca tttgataaaa
    56821 aaacaaacga atcaacaaca tatcatttat tgaataagct tctttttcta taatctgagg
    56881 catatgttcc tcaagtatta actctgcata ttcaggcctt ctagttctag aagtatccaa
    56941 acacgcctgc aatacttcac atgctaattg ttcttcttta ggaagattat caaagtatgt
    57001 tttataaatc tcttccaaac acgcttcctt cttatcgtac tcctcttctt taccatagat
    57061 tggttcacgt aaaatctggt atttcaattc taaataagca gaaggaagag ctgaaaaatc
    57121 cggcataagg ctataaactg gaactcctag ccggcgagca atataggcta acttgggcaa
    57181 actcggttgc gaagctccac tttcaattcg cgacagttga cgaactgtca gttcttgctc
    57241 atctccacaa aaatctggac gactaattcc tttttctatc cgaatctctt taattttttg
    57301 accaattaac atcagacgcc tcctcttcta cctgcttcga aaaatactgt gaaacttaaa
    57361 aaattgtaac ggctacatct ttcctactca taagatttca tagcttcttc cacttctgcc
    57421 aaagtaaccc caaacaactc taggcgtttg aggagttgct tgccgttgga atagccgatt
    57481 cggagagtct ctccgagata ttctctacgc ttacggctgt ctgcccctgc tagaaaacca
    57541 aggcgaatca agtcgctacg actaatgtca aactgactct catgttcaaa ttgttctgtc
    57601 acctgagcta gagccgtttt caggtcttca tagctggcat gctcaattcc cagagaacgc
    57661 cccttggtct tggacttggg aacagcttca tctcgcttga gaaaggcatg ctgaactgtt
    57721 ggaatggccg tcataatcat gcgccgaatc cgctccccat taaaatctgg gtctgtaaag
    57781 acaatgactc catgacgttg gtgtagacgc tgaattcgct ctatatcctg atcattgatg
    57841 gcagaacctc gtgtctcata ggtctccaca tcgaaataac gcttgagatt gaccgtatca
    57901 tcgcgacctt caaccacgat aacttgagaa attttctctt tcattacttg ctgtccaatc
    57961 caaaaattcg ttctgcattt gcagtcgttt ctaccgccag ctcttctgtc gtcataccac
    58021 gcaagtcagc gataaagtcg accacatagc gagtataggc tgttttattt tcacgaccac
    58081 gcttgggtac aggtgctaag taaggcgcat ctgtttccac caaaatcttg tccaaaggta
    58141 actctttagc tgcttcttgg aggtcagttg ccttcttgaa agtcaccact cctgagaagg
    58201 aaatggtcat accaagatcc acaaacttct ctgcccactc aagcgtccct gaaaatgaat
    58261 gcatgatacc accacgagga ccaacgccct cactcttgat aatctcatag gtatcttcca
    58321 gcgcatcacg ggtatggaca acaaaaggca aatccaagtc cttagatagc tgaatctgac
    58381 gacgaaaaac ctgctcctgc acctctttgg gcgctgtcat ccaatggtag tctaagccaa
    58441 tttcacctag agccacaacc ttgggatgtt ttaacttatc caacaagtaa gcctcaactt
    58501 cctctgtata agtaccagct tctgtaggat gccaaccaat agtcgcatag agctgctcat
    58561 actcatctac caactccaag gcacgctcaa tcgtcggttt atcaaaacca acaatattca
    58621 tctgtatcac acccatctca gcagccaagg caatttcttc tgcctcacga cctgcaaatt
    58681 cttctacatt caagtgtgta tgtgtatcaa aaatcatctc ttctaacctc gttttctatc
    58741 ttctattata ccaaaaaaga ggaggagcac ctaatttttc ggtttcccct cctctcttca
    58801 atagagagct attctgctat cttttctatc cgatattgcc catctcctat tccacagtta
    58861 gagacagaag agattggcta cattgataga atattcctat tcagctaaag tatgtgatta
    58921 tcttgggttc tcacttttct cacccatcac taggattgat gacttctcaa aatccccctt
    58981 ataatctaac tttaagtaga gaatagaatt ttctagctgt tctattttct acgtctagtc
    59041 tttcttccta gcaaagcaaa accacttgtt gccaccacta gaccaagact agcaagtgct
    59101 gcacttgatg ctgaacctgt gttaggtaat tgtttgccag caggtgactg gtaggtaaca
    59161 tcttgcattg ttcctgcagt tgcttgcggt gcacttgttg tcttaggagc agcattagga
    59221 gccactagtc tcttaggaac tgtaaccgtg gcaatggctt gcactccaat cgtttctgct
    59281 tccttcacat cttccatagt tttcgcattt tcaatctctt tgagagctgc ttgtttttct
    59341 gcttccactc ttgctaaaag ttctgctttt tctttatcag aaagcggtgc gcctttgatt
    59401 tcatcctgct tgttcttggc tgctttttca atggcatttt tagctgattc tttttcagta
    59461 gctaattgct tagaagcttg tgattgagct gagttttgtg aacctgtgtg agctgatcca
    59521 cccgcctggc taccaccgcc tgcattcgca ttagcatctg agcttccagt attgcctccc
    59581 ttatctccac ctggtgtatt ttctagctta tactctggtg tagcttcttg agttacagat
    59641 tcacctttcg cagattgttg aactgtatct tttcctagaa tcgtcactac tgaaccatct
    59701 gggaatgtga ttgttgctgt accatctcca gctacattga ttgtcgctcc atctaatgct
    59761 gaaccatttg cttgtaaaat agcaacctta actttttctt catctgttaa atgagttata
    59821 tcttttacat ctactctttg agcaggtgct ttaacagttg atttttcagc agtcggttta
    59881 gtgctatctt gtgcttttgg atcttgtgct accaattgat ttcctggaat tgtaatagct
    59941 gaaccatctt taaagacgat tgtcgctgtg ccatctccag ctacttcaac tttatagtaa
    60001 aatgaaataa taacaggaca aatcgatcag gacagtcaaa tcgatttcta acaatgtttt
    60061 agaaatagag atgtactatt ctagtttcaa tctactataa catcgcttcc gaatccattt
    60121 gcatctactg aactttttta caaaaataaa aatcagtaga ctcgagttcc tactgatttt
    60181 tgatagaatt cgtttggatt atgcagccaa aactttgcgt cctttacgac gacgagctgc
    60241 caatacgcga cgaccatttt tagttgacat acggttacgg aatccgtgtt tgcgcgcacg
    60301 acgaagttta cttggttgat aagtacgttt cacgatgaat acctcctcat agattttgta
    60361 ttcgtttagc cggctataaa gtgatcagtt actaaacata ctttactatt ctatctgatt
    60421 ctttcacttt tgtcaatagc tctaggcaaa tgtttccagc tttttcgaat gcaagcccta
    60481 tctacgatac tgtttcaaga aacgagtcat cttttcttgg atttgggcta actcatcaac
    60541 acgaggaagg taaacgatac ggaagtggtc tggttcctgc cagttaaagc ctcgaccatg
    60601 aaccaagaga accttttcct gcttcaagaa atcaaggaca aactgctcat catcatcgat
    60661 acggtacata ttgcggtcga tttttgggaa gatatagagc cccgccttgg gtttaacggc
    60721 agacaaacct ggaatatctt gaatggcatt atagatgaaa tttctttgct cgtagattcg
    60781 tccaccagga agaagcaatt catcgactga ttggtgaccc cccaaggaag tttgtacgac
    60841 ttgttgggcc aaaacgttag agcaaaggcg catattggac agcatattga gcccttcgat
    60901 atagccctta acatgagtct tagggccaga caagaccatc caacccacac ggaaacctgc
    60961 tatgcggtgg gattttgaca gaccattcat gctgacacag aagacatctg gtgccaagct
    61021 cgccacaggc gtatgcacat gtccgtccat taccatgcgg tcatagattt catccgcaaa
    61081 gataatcaaa tcgttttgac gggcaatctc aataatctcc agcaagagtt ccttaggata
    61141 aagggctcca gttgggttat ttggattgat aaggacgatt gccttggtat tggaagtgat
    61201 ttttgacttg atatcgtcaa tatctgggta ccattcaaca gcttcatcac agatatagtg
    61261 aacggcattt cctccagcta ggctgacagc cgccgtccat agaggatagt ctggcattgg
    61321 cactaagacc tcatccccat tgtccaaaag cccctgcatg gacatgacaa tcaactcact
    61381 gacaccattt ccaaggtaaa tatcatcaat atctacgttt gggaatttct tcagctggca
    61441 atactgcatg atggccttac gggctgagaa aatccctttg gagtcagaat agccttcact
    61501 atcacgcgca ttcataatca agtcatgaat gacctcgtct ggcgctgtaa agccaaattc
    61561 tgctggattt cctgtattca gacgtaaaat cttttctcca ttcgctcgca tccgcatggc
    61621 ttcttccaat acaggaccac ggatatcata agcaacatgc tctaacttac tagacttgtt
    61681 atattctttc atcttgtttc ctcaattcat caggatagta acattatacc actagaaaga
    61741 gaatgcgaca agtttactga aatgtgttac tagtttcgta tagaagaaaa accttgctaa
    61801 aggcgaggtt aagaacgtag agatagcagg tattttgcaa agacacatca cataccaaaa
    61861 gataaaccta gaaaaagcaa gcctagaaag gagtcataaa gaagattaaa catgaggaaa
    61921 agcccccata tcatcaagta atcccaacgc ccacttcgtt ttgcaactag aaataagatt
    61981 agatggtaga gtacatgaaa gactaaaaat ccaataaaat ctggataaag aagcggtacc
    62041 agactctcta attgccagat catgatcact tctaccaaga ctgaaactag gataattcca
    62101 taataaagga aatttgattt ttgaaaagag tttttcatca ttctcccttc cttcacttct
    62161 ttcctgctat cctttctttt attttatcat atatttatat agattttaag ccctaatatt
    62221 cttttgaaaa atactttttt tgctttactt ctatagtgaa aaggtttaca attatagtaa
    62281 gaaaatttca ggaggtttca ttatggcaca acgttaccaa aatatcatgg tcgcaatcga
    62341 tggttctaag gaagcggact tggcttttgt caagggagtt cattctgctc tacgaaacga
    62401 cgctaaactc accatcgcac atgtcattga cacacgcgct ctccaaagcg tatccacctt
    62461 tgatgctgaa gtttacgaag aactccaagt cgacgctgaa agtctgatga aagagtacga
    62521 aaaacgtgct aaagatgctg gggtagcaga tgttcatatc gtcattgaaa tgggaaatcc
    62581 aaagaccctg ctagcacgta ctattccaga tgccgaggaa gtggacctca tcctcgttgg
    62641 cgcaactggt ctcaacgcct ttgaacgcct cttggtcggc tcttcatctg aatacatact
    62701 ccgccatgct aaggtcgatt tgctggttgt gagagaacaa gaaaaaacct tataatcaca
    62761 aagaaaagga gcccctagct cctttttgtt tacgatttat ttctctcttt atggcgttcg
    62821 taagccttga gctggcgctg cagttccttt ttaatagcag gttctggagc atatttttct
    62881 tcccaattat ctggttttaa gattttatgg gtcactggat caaaatgagc cttgccatct
    62941 ggaaaaattt tccccatatt ggcctgatgg acaatatcaa aaatacgttc tgggtccacc
    63001 cccatcaaga caaaactgcc gtaggtgaag taaagcgtgt caatcaaggc atccacttgc
    63061 cctatcaaat cttgctgagc aggtgtcttc ttggctactt tacctgctgc cttatcaagg
    63121 gcctgatgaa gttgcgatac agcttgacca aaatcttctt cagaaggact ggctgatcga
    63181 acaaactcca ccaattcttc tattttaaaa ccagccctat gggttgcacc ctctaaatcc
    63241 caagctcgag gttcttcttg ggttcgttca tccatcatgt ggtggaaggt cttgacctta
    63301 ttgaaatgat agtcacggct gacaaaaact ttttctgaag acaaaacacc aaaatgttcc
    63361 aaggccttgt ggatcccatc ttgttgattg ctagtggtaa tgtgcttggc agcttccttg
    63421 acactgctac taccatttcc catagcgacc gacataccga cgccagccag catttcaagg
    63481 tcattatctg agtcaccaaa agccatgact tggttgaggt caaagccata ttctttccca
    63541 actcggcgaa tgccttctaa tttagaattt ccctgattga tgacatccga tgcaaaagga
    63601 ttgctacgtg tcaatttcaa gtcttcaaaa tcagctgccg ccttctcaga ttcttctggt
    63661 gtcatcagca tcaaaacttg gtaaataggt tgattcatca ggtgaagcag gtcctcttcc
    63721 ttttggggaa caaccttgct gaccatgcga ttaaaagact gactcaccgt ccgagttaaa
    63781 acagagggaa cgaagcgact aattcgttgg gaaaaagaac ccagaccaaa ggacatgatt
    63841 ttagaaccca acatggcatc cttggtccct aaggcaatct ccgtgccctc ttttttagca
    63901 tagctaatta gatggcgcaa atgtaacttg gaaatagggc tcgtgaacaa gactctgtct
    63961 ttactaaaga tatactggcc attataggtt accgcaaaat ccagatccaa atcgtccatc
    64021 aattccttaa caaaaaaagg tcctcgccct gtcgctacgc caactagtac cccttgttct
    64081 ttgacaatct taatcgcatc cttagtggat ttcaaaacac tcttgcgatt gttgaccaag
    64141 gttccatcga tatcaaaaaa aacagctttg acttccatcc tatcccaatc tccccttttg
    64201 tgatacaatg attataccac atttcagaaa gagtgagtaa atcatgccta agaaaatcct
    64261 tgttttacat acgggtggaa ctatttccat gcaggccgat gcttctggcg ctgttgtgac
    64321 gagttcagat aatcccatga accatgtgtc caacccactt gaaggaatcc aagtccacgc
    64381 cttggacttt tttaaccttc caagtcccca tatcaaaccc aaacatatgc tggtcctcta
    64441 ccagaaaatt aaagaggaag cagataacta cgatggagtg gtgatcacac acggaaccga
    64501 tactttagag gaaacagcct atttccttga taccatggaa gttccccata tgcctatcgt
    64561 tctaacagga gccatgcgta gctccaatga actcggtagt gatggtgttt ataattacct
    64621 aagtgcttta cgagtggcca gcgatgacag ggctgctgac aaaggagttt tggtcgttat
    64681 gaacgatgaa atccacgctg ccaagtatgt caccaaaaca catacgacta atgtcagcac
    64741 cttccagact ccaacacatg gcccccttgg tctcatcatg aaacaggaaa tcctctactt
    64801 caaaacagct gaacctcgtg ttcgctttga ccttgatcac atacaaggtt tagtccctat
    64861 catctcggct tatgctggta tgacagatga gctgattgat atgctggatt tagaacactt
    64921 ggacggtttg attatccaag ccttcggagc tggtaatatt cccaaagaaa cggctcaaaa
    64981 attagaaagc cttctgcaaa aaggaattcc agtcgctctg gtatcacgat gctttaacgg
    65041 tattgccgag cctgtttatg cctaccaggg tgggggcgta cagttgcaaa aagcaggcgt
    65101 tttctttgtt aaagaactca acgcccaaaa agctcgcttg aaactcctca tcgccctcaa
    65161 tgccggacta acaggacagg ctttgaaaga ctatatggaa ggctaatact cttcgaaaat
    65221 ctctgcaaac cacgtcacgt cgccttaccg tatgtatggt tactgacttc gtcagtttca
    65281 tctacaacct caaaacagtg tgttgcgcag cctttaacca gccgcctagt ccgctctatg
    65341 gtattcatta agtcaacatc tcttgtttaa gagcacaaaa tcaggaaatc ttctcgattc
    65401 cctgattttt tctatttacg ttttcgtgtt gagctacgtt ctgtcaaacc atgaggtaag
    65461 agaacttcac gttcttccaa ctcttcctta tgcataatct tggtcaacat acgcatacta
    65521 atggcaccaa ggtcataaag aggttgggca atcgttgtca agtttggacg ggtaaagcgt
    65581 gagatttgtg aatcatcact agtaataatt tcaaaatctt ctggcacaga aacaccctta
    65641 tcagccaaac cgttcaagac tcctgctgcc aactcatcac ctgtcacaac tgctgcagtt
    65701 gcatttgatg aaatcaaacg ctctgctaag gcgtaaccat catcatagct atatttagat
    65761 tcaaatacca aaccctcact ataagtgatt cctgcttttt tcaaggtttc cttgtagcca
    65821 actaaacgaa ccttaccatt gatgtcatcc actagcggac cgctaacgaa agcaatacgc
    65881 tcattttctt tagcaaggta actcactgca tcaattgttg cttgcttata gtcaatattg
    65941 acacttggca actggtgctc aacatcgaca gttcctgcga gaacaatcgg agtacgtgaa
    66001 cgcgaaaatt ctgagcgaat tttatctgtc aagtgatacc ccatatagat aatgccatct
    66061 acctgctttg aaaagagggt attgacaaca gaaacttctt tctcgttatc ttcatcgcta
    66121 ttagctagga caatattgta cttgtacatt tctgcaatat catcaatccc cttagccaaa
    66181 ctcgaaaaat aaccattggt aatatttgga atcacgacac cgacagtggt tgtcttttta
    66241 cttgcaagac cacgcgcaac tgcatttgga cgataatcca aacgatcaat tacctctagc
    66301 acttttttac gggtattctc ttttacattt ttattgccat tgaccacacg gctgaccgtc
    66361 gccatggaaa cacctgcttc acgagcgaca tcataaatgg ttactgtatc atctgcattc
    66421 attccttttc ctgtcctttc tatctcacac attcttttac aagtagaggt actgattgaa
    66481 gctctatatc tacttacaaa agtgaagatg tgaaaatttc gttttcatat ttctacttat
    66541 tccattctat cactaattgt aaacactttc aagtgttttt tgaagattga ttgaaaaaat
    66601 ttcatagaaa acctaggttt agctccttgc taccacctta gactaaacaa aaaggaggaa
    66661 actaagccct cctaaagtta tagtaaaatg aaataagaac aggataaatc gatcaggaca
    66721 gtcaaatcga tttctaacaa tgttttagaa gtagaggtgt actattctag tttcaatcta
    66781 ctataggtat tgttccattc actaccgtca attttagcac atagtcttca tgaaaatatt
    66841 atatcatcat aaccaaccag attcttttgc gatattagct gcctctgttc gattaccagc
    66901 atccagtttt gaaagaatat tggtgacata gtttcgaata gttccgtttg agaggtaaag
    66961 ctgatctgcg atttcttggt tggataagcc ccgggcgatt ccctttaaga cagcaatctc
    67021 ttgttctgtc aacggattgg gacgggtcat caccatttcc atcaattcag gcgaatactc
    67081 cttgcgtcct tcgaggacgg tgtgcaaggt ttgcatgagg tctgcaatgc ttcgttcctt
    67141 taatacataa gcatccactc cagccttgac cgcacgttca aaatacccag cacgcttgaa
    67201 ggtcgtcacc acaaccacct ttgtttcaag cttttctgat cgtatccact ccaagacttc
    67261 aagacctgtc ttaacaggca tttctacgtc aaggatggcg atatctacag actccttttc
    67321 taatagttgg attgcttctt gcccattctt ggcttgaagg acagactcca catctggttg
    67381 aagcgtgagc aattgacaca tggcatctcg caacatactt tgatcttctg cgactaatac
    67441 tttcatctta gtttctctcc ttataaggta gtcgaacttg cacttccgtt ggatgtttct
    67501 gactgattac acttacttct cctgaaaatg gaaaaacacg atctcggact gtatggagct
    67561 catctccttt tagaaaagca aagccgcagc catcatcact tactgttaaa atgagttcct
    67621 tctctgtccg ttctaatttt aagtaagctt tagacgcttt ggcatgtttg atgatattgg
    67681 tcaccaactc aagcaaaatc atagaagcca ttgactccaa ttcttgagta aggctagcag
    67741 tatctagttg gttatccgtt tccacctcaa ttccagcaat ttctaacatc tttttcacag
    67801 tctctagttc ggatgtcaaa gttctagact taagattttc cacgatagtt cgaacttcat
    67861 tcatggaatc cttgctgatc tggtgaattt cttttaattc cttttccacc tgtggataag
    67921 cctccatctg aaataactgc aaggctagat cagttttaac actaagcata gcaaaggtat
    67981 gccccagact atcatgcaaa tcttgaccga tacgattgcg ttcattttca gcaagcaata
    68041 gatttatctg agcattttgc ttgacctgag cttctttcaa atcctcgaca atacgaatcc
    68101 gaaccaatcc aaaagtcatt aaatcgacaa aagtaagaat tacaagtaga tagaatagaa
    68161 actcaacttc gattctctga aaaatcaaca gttgccccac aacaaggact tgagcaagaa
    68221 gaaaagtcca gacatgtaaa gactttaaac tacgtacgct gaaatgataa cttaagagat
    68281 tggataggaa aaagaaaaac cagatataat taacagcaac aaaggcagta ttcccaacta
    68341 cataagtcag catgaggccc caatatagcc aagataggcg ctggctctta gttgttaaaa
    68401 cacccaaata tgccactaca aatagaatat caatcaataa atgccaggca gaaagccacc
    68461 cagtcactac agacaggatg gggaaaatca taaaaattaa actgatccaa aacatataat
    68521 gtattctttt cagtctttca agcattaagc attctcctta tgaccttgaa ggtaaatagt
    68581 caaaccaaat aaaactgctg aaaaaacaag tagataaact gtggctgata gattgattcc
    68641 accctcattt aagaaggtct tgattaattc catcaactga taacttggta aacgcttccc
    68701 gattgcttgc atccagtctg gaaataaaga gacgggcatc cagagtccgc ctaaaacagc
    68761 caatcctaga taaagaagat tgcccacgac agacatcagc tgactagttg gtaacagcgt
    68821 caaggttaag ccaagtgcta caaaagcaat acttcccaaa atcagcaaaa tcgcagctcc
    68881 aacccatttt actagaggca tgtctacacc tcttacaaaa tgtccaactg taaaaacaac
    68941 cagaattgag accaaataat caaccagcat acttgttatc tttgatagat aatattctac
    69001 catatttact gggctatgac gtaatatttt ctgccagttg ttcatcttgt cggtatgtaa
    69061 gacagctggg aatgaaaaga tagcggtcga catcatggaa aagccagtca tggagatgag
    69121 gtaatcacgc ataaaattcg cgggtccacc tggtgtgtcc tggtacatgc cagaaaagaa
    69181 tagatagaag gctgtcggca tccctactga caatagataa tagatcaatt gtcgtttggt
    69241 caataaaaat tctatcttac taagtgctag ccatcgtttc atcttagtta tctcccttct
    69301 gcgtttcttc aaagattgta tccaacaaac tacgattatt aacttcaatt tcttgtatgc
    69361 cacatcctgc ttgaactaac agttcccaaa aagcatctgc ttcgcgtgtg actacttgta
    69421 gagcatcctg tttttgtgac cagttttcaa ccaagttaga ctgctcaatg acttccttgt
    69481 atgccagagg aaggataaaa tgcttttcaa ttccctcact acgcatagct agaggcgtcg
    69541 tatcacgaat caactctccc ttatttaaaa ccaaaatccg gtcagccgta tgctctacct
    69601 cttcaatata atgagacgaa tagagaatcg tgactccttg cgcttttagg tcccgaacga
    69661 tttcccaaaa gcgttgacga gttgaagtat ccatggcagc agttggttca tctaaaaaga
    69721 caagctttgg tcgcccaatc aaggtcaaga caaaagagaa gagacgcttt tgcccgcctg
    69781 acaatttttc tgcgaattgc tctttttgtt gctggtcaaa ctgcaatagt tgatcgattt
    69841 cctgatcgct caaggaattt ggatagatac gttgaaagaa agcaatcaac tctttgacct
    69901 ttaatttctg aacgatgaca ttttcttgag gcagataacc tctaatatag tctaactgag
    69961 aactcgtcac tgacaagcct tggatggata cttgaccgct tgtgaccagt ttatctccaa
    70021 gcagacagtc caagagtgtg gtcttcccag caccattggg cccaatcaag gcgacgcatt
    70081 caccttcagc tacctcaaag gaaataccct tcaaaatagc cttgcccttg atgtttttat
    70141 ttaggctttc taccttaatc atattcatga tattctcctt tcaaccactc cattctcata
    70201 aggaaaacga cgaaaatcat aaatccaaac cccaaagcac cacgaatgaa ttggcgaagc
    70261 aaggtttggt caaaccaacc tgtaaacatt tccactaacc ataccaagag tgacaggccg
    70321 ataaagaaat agatgatccc tctcttcatt cctcaaactc ctttttcaca tctccgacta
    70381 atttcaaacc ttctctaaca agccaagaca tcattccaaa gccagcaaag agctcccaag
    70441 gaaaatgata gaaactctca tccaatcccg aaaacatgag ttaggtcata actcctgcta
    70501 ctactaaact cactgcgata atcattttat ttctcatctc ttcttcctcc atttcatact
    70561 acaattatag tcttttgaaa tcagaggaga cagaagcttc tgtcactaga aaatatgaca
    70621 aatgtcataa aaaattctgt tcaaaacaag caagatacac tatacaataa aacacaatca
    70681 gaaaaatcta aggcaacttc ctcaaaagag atatcaaacc caattcacac cataatgtaa
    70741 actaatactt atttaaaatc aaaaagagta gaaattttta tcagacaaac acatatatag
    70801 tgtattgaat ctataacagt agggcttaaa tactaacata tttctataaa ttaatttaac
    70861 tttcctgata gagctgttca tatcttattt caattctcta tattatacgt tgaacaaaac
    70921 ccttctattg ctttcttaaa aatttataag agttataaaa tctgttaaat ttcaatgtgt
    70981 atacctaaac tacggtattt attgaaaaga ctggggacaa aaagtatacg ctgccaaaat
    71041 gaattactga aaatcaaaaa agagagaacc aaactgattc cctcttaatg tatataatat
    71101 ctagttttaa aaatacacac tcacatatct ctgt
//
LOCUS       DAVHTH010000003        68665 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.003, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000003 DAVHTH010000000
VERSION     DAVHTH010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 68665)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 68665)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..68665
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.003"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            9..416
                     /locus_tag="VVR63_000181"
     CDS             9..416
                     /locus_tag="VVR63_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001824294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase C-terminal
                     domain-containing protein"
                     /protein_id="HEU6128247.1"
                     /translation="MWKVAQRELATGFYYGIPSENEQLFGARRKIPEYKFVAEVVSYD
                     DAVQTATIRQRNVINEGDQVEFYGPGFRHFETYIEDLHDAKGNKIDRAPNPMELLTIK
                     VPQPVQSGDMVRALKEGLINFYKEDGTSVTVRA"
     gene            431..742
                     /locus_tag="VVR63_000182"
     CDS             431..742
                     /locus_tag="VVR63_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6128248.1"
                     /translation="MIEAQGFLVDKQTRCIHYHSKLDIIALQCYDCKKYYACYRCHDS
                     LENHPFEPYPLSLIQDKPILCGVCLKLLTYKQYKESLSCLFCFSRFNPGCQNHKERYF
                     K"
     gene            1002..1730
                     /locus_tag="VVR63_000183"
                     /pseudo
     CDS             1002..1730
                     /locus_tag="VVR63_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
     gene            2193..2958
                     /locus_tag="VVR63_000184"
                     /pseudo
     CDS             2193..2958
                     /locus_tag="VVR63_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812989.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            2974..3453
                     /locus_tag="VVR63_000185"
     CDS             2974..3453
                     /locus_tag="VVR63_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6128249.1"
                     /translation="MKLNKQKNRMIYVLSNFLYAISVSIIYALNGIVLLVIVSKLGIP
                     GDLGLDFIVAIVVNTILLVLFYFLLSYIFYLYKLKSGLVFGILVALLLFIPNILNTMM
                     MNTSNDLFIKAIELLPFYSLPVFVASNTMSISQYLVVITTIILLYFFTLKKSKKYSF"
     gene            3839..4048
                     /locus_tag="VVR63_000186"
     CDS             3839..4048
                     /locus_tag="VVR63_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU6128250.1"
                     /translation="MAKNLKLKLARVERDLTQGQLAEAVGVTRQTIGLIEAGKYNPSL
                     SLCQSICRCLGKTLDQLFWEEEDEK"
     gene            4038..4526
                     /locus_tag="VVR63_000187"
     CDS             4038..4526
                     /locus_tag="VVR63_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6128251.1"
                     /translation="MKNRFYYYQLLDEREEQLFNKAGSESFYICIALSLLSYIISVLA
                     PSLFNSNMLLIVIIIGTFYFFNRARYLGVTYYSRFHFTILGCFFLTLAITALLMLQNY
                     QFNIEIYQHNPLNFKYLSAWVITYIIYLPWIFIGNLGLKSYGEWAQKKFEQDMDELES
                     GE"
     gene            4642..6102
                     /locus_tag="VVR63_000188"
     CDS             4642..6102
                     /locus_tag="VVR63_000188"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HEU6128252.1"
                     /translation="MYPDDSLTLHTDLYQINMMQVYFDQGIHNKKAVFEVYFRQQPFK
                     NGYAVFAGLERIVNYLEDLRFSDSDIAYLESLGYHGAFLDYLRNFKLELTVRSAQEGD
                     LVFANEPIVQVEGPLAQCQLVETALLNIVNYQTLVATKAARIRSVIEDEPLMEFGTRR
                     AQEMDAAIWGTRAAVIGGANGTSNVRAGKLFDIPVLGTHAHALVQVYGNDYEAFKAYA
                     ATHKNCVFLVDTYDTLRIGVPAAIQVARELGDQINFMGVRIDSGDIAYISKKVRQQLD
                     EAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVAIE
                     DETGQMRNTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITYDGVDISDMTEIKM
                     FHPTYTYIKKTVRNFDAVPLLVDIFKEGILVYNLPSLTDIQDYARKEFDKLWDEYKRV
                     LNPQHYPVDLARDVWQDKMDLIDKMRKEALGEGEEE"
     gene            6099..6923
                     /gene="nadE"
                     /locus_tag="VVR63_000189"
     CDS             6099..6923
                     /gene="nadE"
                     /locus_tag="VVR63_000189"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HEU6128253.1"
                     /translation="MSLQETIIQELGVKPVIDAQEEIRRSIDFLKRYLKKHPFLKTFV
                     LGISGGQDSTLAGRLAQLAMEELRAETGDDSYKFIAVRLPYGVQADEADAQKALAFIQ
                     PDVSLVVNIKESADAMTAAVEATGSPVSDFNKGNIKARCRMIAQYALAGSHSGAVIGT
                     DHAAENITGFFTKFGDGGADILPLYRLNKRQGKQLLQKLGAEPALYEKIPTADLEEDK
                     PGLADEVALGVTYAEIDDYLEGKTISPEAQATIENWWHKGQHKRHLPITVFDDFWE"
     gene            7273..7824
                     /locus_tag="VVR63_000190"
     CDS             7273..7824
                     /locus_tag="VVR63_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6128254.1"
                     /translation="MKSIGTQILQTERLILRRFVESDAEAMFQNWASSAENLTYVTWD
                     PHPDVEITRNSIRNWVASYTNLNYYKWAICLKENPEQVIGDISIVKIDEADLSCEIGY
                     VLGKAYWGHGMMTEALKAVLDFCFTQVGFQKVRARYASLNPASGRVMEKAGMSYLQTI
                     VNGVERKGYLADLIYYGISREEC"
     gene            8538..9230
                     /locus_tag="VVR63_000191"
     CDS             8538..9230
                     /locus_tag="VVR63_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEU6128255.1"
                     /translation="MNTSFVHAADGIQYVRDDTRDKEEGIEYDDADNGDIIVKVATKP
                     KVVTKKISSTRIRYEKDETKDRSENPVTIDGEDGYVTTTRTYDVNPETGHVTEQVTVD
                     RKEATDTVIKVPAKSKVEEVFVPFATKYEADNDLSAGQEQEITLGKNGKTVTTITYDV
                     DGKSGQVTESTLSQKEDSQTRVVKKGTKPQVLVQEISIETEYLDGPTLDKSQEVEEVG
                     EIGKLLLLQSIL"
     gene            9284..9673
                     /locus_tag="VVR63_000192"
     CDS             9284..9673
                     /locus_tag="VVR63_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEU6128256.1"
                     /translation="MVKRRIRRGTREPEKVVVPEQSSIPSYPVSVTSNQGTDVAVEPA
                     KAVAPTTGWKQENGMWYFYNTDGSMATGWVQVNGSWYYLNSNGSMKVNQWFQVGGKWY
                     YVNTSGELAVNTSIDGYRVNDNGEWVR"
     gene            complement(10334..11362)
                     /gene="queA"
                     /locus_tag="VVR63_000193"
     CDS             complement(10334..11362)
                     /gene="queA"
                     /locus_tag="VVR63_000193"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HEU6128257.1"
                     /translation="MNTADFDFHLPEELIAQTPLEKRDASKLLIVNRETGEMQDKHFH
                     SIIDMLEPGDALVMNDTRVLPARLYGQKVETGGHVELLLLKNTSGDEWEVLAKPAKRL
                     KVGTRISFGDGRLSAVVTEELTHGGRIVRFEYQGIFLEVLESLGEMPLPPYIHEKLDD
                     RERYQTVYAKESGSAAAPTAGLHFTKELLAEIQAKGVHLVYLTLHVGLGTFRPVSVDN
                     LDEHEMHSEFYQLSEEAAATLRSVKENGGRVIAVGTTSIRTLETIGSKFDGQIQADSG
                     WTNIFIKPGYEWKVVDAFSTNFHLPKSTLVMLVSAFAGRELVLDAYHHAIQEHYRFFS
                     FGDAMFIY"
     gene            11513..12220
                     /locus_tag="VVR63_000194"
     CDS             11513..12220
                     /locus_tag="VVR63_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HEU6128258.1"
                     /translation="MKVIKVENQVQGGKVAFEILKEKLANGAQTLGLATGSSPLEFYK
                     EIVESDLDFSNLTSVNLDEYVGLDGDNPQSYRYFMQENLFNQKPFKESFLPRGVKDNA
                     EAEVERYNQILADHPVDLQILGIGRNGHIGFNEPGTPFDSQTHLVELDQSTIEANARF
                     FAKIEDVPTQAISMGIKNILDAKSIILFAYGESKAEAIAGTVSGPVTENLPASSLQNH
                     PDVTIIADAEALSLLEK"
     gene            12360..12536
                     /locus_tag="VVR63_000195"
     CDS             12360..12536
                     /locus_tag="VVR63_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HEU6128259.1"
                     /translation="MSKTVVRKNESLDDALRRFKRAVTKAGTLQETRKREFYEKPSVK
                     RKRKSEVARKRKKF"
     gene            12666..13601
                     /locus_tag="VVR63_000196"
     CDS             12666..13601
                     /locus_tag="VVR63_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HEU6128260.1"
                     /translation="MSVLVKEVIEKLRLDIVYGEPELLEKEINTADITRPGLEMTGYF
                     DYYTPERIQLLGMKEWSYLISMPSNSRYEVLKKMFLPETPAVIVARGLVVPEEMLKAA
                     RECKIAILTSRAATSRLSGELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDIFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAVYLENYDTHKTFDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIE
                     AAAMNYRAKEMGFDATRLFDERLTSLIARNEVQNA"
     gene            13594..14382
                     /locus_tag="VVR63_000197"
     CDS             13594..14382
                     /locus_tag="VVR63_000197"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000609710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HEU6128261.1"
                     /translation="MLDPIAIQLGPLAIRWYALCIVTGLILAVYLTMKEAPRKKIIPD
                     DILDFILVAFPLAILGARLYYVIFRFDYYSQNLGEIFAIWNGGLAIYGGLITGALVLY
                     IFADRKLINTWDFLDIAAPSVMIAQSLGRWGNFFNQEAYGATVDNLDYLPGFIRDQMY
                     IEGSYRQPTFLYESLWNLLGFALILIFRRKWKSLRRGHITAFYLIWYGFGRMVIEGMR
                     TDSLMFFGLRVSQWLSVVFIGLGIMIVIYQNRKKAPYYITEEEK"
     gene            14383..14766
                     /locus_tag="VVR63_000198"
     CDS             14383..14766
                     /locus_tag="VVR63_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HEU6128262.1"
                     /translation="MLEVAYILVALALIVFLVYLIITVQKLGRVIDETEKTIKTLTSD
                     VDVTLHHTNELLAKVNVLADDINVKVATIDPLFSAVADLSLSVSDLNDHARVLSKKAS
                     SAGSKTLKTGASLSALRLASKFFKK"
     gene            14782..15171
                     /locus_tag="VVR63_000199"
     CDS             14782..15171
                     /locus_tag="VVR63_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEU6128263.1"
                     /translation="MGKLSSILLGTVSGAALALFLTSDKGKQVCSQAQDFLDDLREDP
                     EYAKEQVCEKLTEVKEQATDFVLKTKEQVESGEITVDSILAQAKSYAFQATEASKNQL
                     NNLKEQWQEKAEALDDSEEIVIDITEE"
     gene            15255..16385
                     /locus_tag="VVR63_000200"
     CDS             15255..16385
                     /locus_tag="VVR63_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HEU6128264.1"
                     /translation="MQKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDSYLEHLLEE
                     FRSYDIEKLSTLYIGGGTPTALSAPQLEVLLNGLTKNLDLSVLEELTIEANPGDLDAD
                     KIAVLKNSAVNRVSLGVQTFDDKMLKKIGRSHLEKDIYENIDRLKLAGFDNISIDLIY
                     ALPGQTMEQVKENVAKAIGLDIPHMSLYSLILENHTVFMNRMRRGKLPLPKEELEAEM
                     FEYIIAELERAGFEHYEISNFSKPGFESRHNLMYWDNAEYYGIGAGASGYVNGVRYKN
                     HGPIRHYLSAVEEGNACITEDHLSQKEQMEEEMFLGLRKKSGVSMARFEEKFGQSFAG
                     LYGEIVRDLVQQGLMQIEGDHVRMTKRGLFLGDTVAERFILE"
     gene            16390..17127
                     /locus_tag="VVR63_000201"
     CDS             16390..17127
                     /locus_tag="VVR63_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000524807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HEU6128265.1"
                     /translation="MGLTYQMKMKIPFDMADMNGHIKLPDVILLSLQVSGMQSIELGV
                     SDKAILEEYNLVWIIVEYDIEVVRLPRFAEEITIETEALSYNRLFCYRRFTIYNEAEQ
                     ELIHMMATFVLMDRDSRKVHVVEPEIVAPYQSDFDKKLIRGPKYESLEEPISKDYHVR
                     FYDLDMNGHVNNSKYLDWIFEVMGADFLTHYIPKKINLKYVKEVRPGGVITSAVERTG
                     LESKHEITSDGVINAQAIITWQEIKKA"
     gene            17138..17911
                     /locus_tag="VVR63_000202"
     CDS             17138..17911
                     /locus_tag="VVR63_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HEU6128266.1"
                     /translation="MKYKGYLIDLDGTIYKGKDRIPAGETFVHELQKRDIPYLFVTNN
                     TTRTPESVKEMLAQNFNIDTPLSTVYTATLATIDYMNDLGLEKTVYVVGEAGLKEAIK
                     AAGYVEDKEKPAYVVVGLDWQVDYEKFATATLAIQKGAHFIGTNPDLNIPTERGLLPG
                     AGSLITLLEVATRVKPVYIGKPNAIIMDKAVEHLGLEREELIMVGDNYLTDIRAGIDN
                     GIPTLLVTTGFTKAEEVAGLPIAPTHVVSSLAEWDFDEN"
     gene            17901..18518
                     /locus_tag="VVR63_000203"
     CDS             17901..18518
                     /locus_tag="VVR63_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HEU6128267.1"
                     /translation="MKTKLTFWGSMLFLLSLSILLTIYLAWIFYPMEIQWLNLTNRVY
                     LKPETIQYNFHILMNYLTNPFSQVLQMPDFRSSAAGLHHFAVVKNLFHLVQLVALVTL
                     PSFYVFVNRIVKKDFLSLYRKSLLALVVLPVMIGLGGVLIGFDQFFTLFHQILFVGDD
                     TWLFDPAKDPVIMILPETFFLHAFLLFFALYESFFGYLCLKSRRK"
     gene            18728..19129
                     /locus_tag="VVR63_000204"
     CDS             18728..19129
                     /locus_tag="VVR63_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007556665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HEU6128268.1"
                     /translation="MITLFLSPSCTSCRKAKAWLEKHKVPFVEHNIMTSPLTRKELQH
                     ILSLTENGTDDIISTRSKIFQKLNIDVESISVSELLHLIEQYPSLLRRPIIIDAKRMQ
                     IGFNEDEIRAFLPRSYRKQELKEARMRAGIS"
     gene            19129..19407
                     /locus_tag="VVR63_000205"
     CDS             19129..19407
                     /locus_tag="VVR63_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HEU6128269.1"
                     /translation="MNKQYSYPLDLSWSTEELASVLSFFNDVEAAYEGKVEAKKLLDS
                     YKGFKAVVPSKSEEKRLGREFETVSGYSLYRAVQAAKEKGEGKISLGK"
     gene            19397..20170
                     /locus_tag="VVR63_000206"
     CDS             19397..20170
                     /locus_tag="VVR63_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HEU6128270.1"
                     /translation="MESKFEFAKELVKKAGQYILDHMQEDLRVETKSSPTDLVTRLDK
                     EVQELLVGEILSRYPEDKICAEEGCLRASVQEGKVWVIDPIDGTNNFVAQQEDFAVMM
                     AYFENGQGQFGLIYDVVKGDCYHGGGEFPVCLNDRPLAPFKTKPLGDFLIAGNSGMLE
                     TNEWGLADLSRAVLGVRVYGSAAISFAKILSGRLLTYLTYLQPWDYAAASILGESLGY
                     RVVTLFGEAPDFQTRQPVMMVPLEMQEEIQSYIYERKRT"
     gene            20171..21475
                     /locus_tag="VVR63_000207"
     CDS             20171..21475
                     /locus_tag="VVR63_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001160253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HEU6128271.1"
                     /translation="MQFPEGFVEKYKEILGDEARDFLASFEEEAVSAFRVNPLKEEQL
                     SFSDAITQTPWGHYGKVSGKSPEHATGLVYSQEPAAQMVAQVAQPSPGMKVLDLAAAP
                     GGKSTQLAAYLAGEGLLVSNEISSKRAKILVENMERFGATNVVVTNESADRLVKVFKG
                     YFDLIVLDAPCSGEGMFRKQPDAMDYWSLDYPSQCASLQREILEDAVTMLAEGGRLVY
                     STCTWAPEENEEIVNWLLEEYDFDLLPVEHINGMVAGIDLPETARMYPHQFKGEGQFV
                     AHLQFKGNNPAPKFKASKSNLSREQVALWQEFAQNHLKVNLPGILQTFGDQLYLLPEL
                     LPDLGKLKIARNGLHLGTFKKKRFEPSFALGLALKSSQVEQSVEIGQEAFVKYAAGEI
                     VQLAESLPNGWYQVLVKGNGLGFAKVTGNVLKNYFPKGLRFK"
     gene            22049..22927
                     /gene="pstS"
                     /locus_tag="VVR63_000208"
     CDS             22049..22927
                     /gene="pstS"
                     /locus_tag="VVR63_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HEU6128272.1"
                     /translation="MKKRKKLALSLIAFWLTACLVGCASWIDRGESITAVGSTALQPL
                     VEVAADEFGTIHVGKTVNVQGGGSGTGLSQVQSGAVDIGNSDVFAEEKDGIDASALVD
                     HKVAVAGLALIVNKEVDVDNLTTEQLRQIFIGEVTNWKEFGGKDLPISVINRAAGSGS
                     RATFDTVIMEGQSAMQSQEQDSNGAVKSIVSKSPGAISYLSLTYIDDSVKSMKLNGYD
                     LSPENISSNNWPLWSYEHMYTLGQPNELAAEFLNFVLSDETQEGIVKGLKYIPIKEMK
                     VEKDAAGTVTVLEGRQ"
     gene            22927..23844
                     /gene="pstC"
                     /locus_tag="VVR63_000209"
     CDS             22927..23844
                     /gene="pstC"
                     /locus_tag="VVR63_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEU6128273.1"
                     /translation="MNQEELAKKMLLPSKNSRLEKLGKGLTFACLSLIVILVAMILVF
                     VAQKGLSTFFVNGVNIFDFLLGGTWNPSSKEFGALPMILGSFIVTILSALIATPFAIG
                     AAVFMTEVSPKGAKILQPAIELLVGIPSVVYGFIGLQVVVPFVRSVFGGTGFGILSGI
                     SVLFVMILPTVTFMTTDSLRAVPRYYREASFAMGATRWQTIWRVILKAARSGIFTAVV
                     FGMARAFGEALAIQMVVGNSAVIPTSLTTPAATLTSILTMGIGNTVMGTVNNNVLWSL
                     ALVLLLMSLVFNSVIKLITKERGKKNYAR"
     gene            23834..24718
                     /gene="pstA"
                     /locus_tag="VVR63_000210"
     CDS             23834..24718
                     /gene="pstA"
                     /locus_tag="VVR63_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009443446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEU6128274.1"
                     /translation="MRAKKLDKLATAVLYTIASIIVTILASLILYILVRGLPHISWSF
                     LTGRSSAFQAGGGIGIQLYNSFFLLVITLIISVPLSMGAGIYLAEYAKKGPVTNFVRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLKHVH
                     HTQREAGLALGISRWETVVHVVIPEALPGIVTGVVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNILSVTSPISIFRQAETLAVHIWKVNSEGTIPDGTIVSAGSAAVLLIFILIF
                     NFGARKFGSYLHKKLTAA"
     gene            24729..25532
                     /gene="pstB"
                     /locus_tag="VVR63_000211"
     CDS             24729..25532
                     /gene="pstB"
                     /locus_tag="VVR63_000211"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEU6128275.1"
                     /translation="MSTYNWDEKHILTFPEEKVALSTKDVHVYYGKNESIKGIDMQFE
                     RNKITALIGPSGSGKSTYLRSLNRMNDTIDIAKVTGQILYRGIDVNRPEINVYEMRKH
                     IGMVFQRPNPFAKSIYRNITFAHERAGVKDKQVLDEIVETSLRQAALWDQVKDDLHKS
                     ALTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKNFTIIIV
                     THNMQQAARASDYTGFFYLGDLIEYDKTATIFQNAKLQSTNDYVSGHFG"
     gene            25545..26303
                     /gene="pstB"
                     /locus_tag="VVR63_000212"
     CDS             25545..26303
                     /gene="pstB"
                     /locus_tag="VVR63_000212"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEU6128276.1"
                     /translation="MTDAILQVSDLSVYYNKKKALNSVSLSFQPKEITALIGPSGSGK
                     STLLKSLNRMGDLNPEVTTTGSVVYNGHNIYSPRTDTVELRKEIGMVFQQPNPFPMTI
                     YENVVYGLRINGIKDKQVLDEAVEKALQGASIWDEVKDRLYDSAIGLSGGQQQRVCVA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLYGLKDKYTMLLVTRSMQQASRISDKTG
                     FFLDGDLIEFNDTKQMFLDPQHKETEDYITGKFG"
     gene            26315..26968
                     /gene="phoU"
                     /locus_tag="VVR63_000213"
     CDS             26315..26968
                     /gene="phoU"
                     /locus_tag="VVR63_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000946475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEU6128277.1"
                     /translation="MLRSQFEEDLEKLHNQFYAMGQEVLSQINRTVRAFVTHDRDLAK
                     EVIEDDAEVNEYEVKLEKKSFEMIALQQPVSQDLRTVLTVLKAVSDVERMGDHAVAIA
                     QATIRMKGEERIPAVEEEIKKMGREVKSVVEAALDLYLNGSVDDAYRVASMDEQINHY
                     FETIRDLATEEIKKNPEAIVTGRDYFQVISYLERIGDYAKNICEWVVYFETGKIVEL"
     gene            27125..27940
                     /locus_tag="VVR63_000214"
     CDS             27125..27940
                     /locus_tag="VVR63_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEU6128278.1"
                     /translation="MKSKKWIFVLCNFLASFFLVACQSGSNGSQSAVDAIKQKGKLVV
                     ATSPDYAPFEFQSLVDGKNQVVGADIDMAQAIADELGVKLEISSMSFDNVLTSLQTGK
                     ADLAVAGISATDERKEVFDFSIPYYENKISFLVRKADVEKYKDLTSLESANIAAQKGT
                     VPESMVKEQLPKAQLTSLTNMGEAVNELQVGKVDAVHMDEPVALSYAAKNAGLAVATV
                     SLKMKDGDANAVALRKNSDDLKEVVDKVIQKLKDEGTYQSYLEKAASLTEVEE"
     gene            complement(27960..29231)
                     /locus_tag="VVR63_000215"
     CDS             complement(27960..29231)
                     /locus_tag="VVR63_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HEU6128279.1"
                     /translation="MKKQSKYKEVVSYLKNGIESERFPTGSRLPSIRQLSLDFHCSKD
                     TIQRALLELRHEQYLYAKPQSGYYVLEQGQHQDLEIEVTDEHASAYDDFRLCVNETLI
                     GRENYLFNYYDNQEGLEDLRQSIHKLLFEQALYCKANQLVLTSGTQQALFILSQISFP
                     SQAKEILVEQPTYHRMNRLLIAQGLDYQTIERGIDGIDLEELEGHFKTGKIKFFYTIP
                     RFHYPLGHSYSEQDKRSILNLAAKYDVYIVEDDYLGDLDSKKGQTFHYLDTEEHVIYI
                     KSFSTSLFPALRITALILPNAIKEAFVAYKNILDYDSNLIMQKALSLYIDSQLFEKNR
                     LARLTNHESYQKQIEERITKTPCPLPHYPLHDGLLLDLRQYPKIASLKHSQLGLDFFE
                     EAYLSTCPYQFAKVSLDNLENVLNYLKAELE"
     gene            29373..30104
                     /gene="budA"
                     /locus_tag="VVR63_000216"
     CDS             29373..30104
                     /gene="budA"
                     /locus_tag="VVR63_000216"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HEU6128280.1"
                     /translation="MDKNVQEPVKLFQYNTLGALMAGLYGGTMTVGELLEHGDLGLGT
                     LDSIDGELIVLDGKAYQAKGSGDQPEIVEVSPDALIPYAAVVPHQAEVIFRQRFEMTD
                     KELKERIESYYDGENLFRSIKIRGEFLHMHVRMIPKSTPDTKFADVATHQPEYSRDNV
                     AGTIVGFWTPEIFHGVSVAGYHLHFISDDLTFGGHVMDFVIKEGIIEVGAVDQLDQRF
                     PVQDRQYLFAKFNVDEMKKDIEKAE"
     gene            30114..30866
                     /locus_tag="VVR63_000217"
     CDS             30114..30866
                     /locus_tag="VVR63_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhfC family intramembrane metalloprotease"
                     /protein_id="HEU6128281.1"
                     /translation="MTIHIIITMLLLLAFLIGSIWFAKKKYQINLAVLGLGAVAFFVS
                     SQILEKLVHILILHPQKDGSIALLQDHPLIYIIYGLAMAAFFEETARLVFFKWLEKKR
                     SLEKADALAYGLGHGGLELIFLGLTSLLNLYIVLSAVQTQNPQVMQLLSENMLKTIQS
                     LSVWQIYLLGFERILALGFQLLLTVWVYQAVRQKKWIYLLAAYGLHAFFDLSPSLFQV
                     GWLTNPVLVEVILALELVLVAYGTKEIFCKKS"
     gene            30978..31928
                     /gene="murB"
                     /locus_tag="VVR63_000218"
     CDS             30978..31928
                     /gene="murB"
                     /locus_tag="VVR63_000218"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000116191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HEU6128282.1"
                     /translation="MSVREKMLEILEGIDIRFKEPLHSYSYTKVGGEADYLVFPRNRF
                     ELARVVKFANQENIPWMVLGNASNIIVRDGGIRGFVILCDKLNNVSVDGYTIEAEAGA
                     NLIETTRIALRHSLTGFEFACGIPGSVGGAVFMNAGAYGGEIAHILQSCKVLTKDGEI
                     ETLSAKDLAFGYRHSAIQESGAVVLSVKFALAPGTHQVIKQEMDRLTHLRELKQPLEY
                     PSCGSVFKRPVGHFAGQLISEAGLKGYRIGGVEVSEKHAGFMINVADGTAKDYEDLIQ
                     SVIEKVKEHSGITLEREVRILGESLSVAKMYAGGFTPCKR"
     gene            31987..33144
                     /locus_tag="VVR63_000219"
     CDS             31987..33144
                     /locus_tag="VVR63_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6128283.1"
                     /translation="MKKPIIEFKNVSKVFEDSNTKVLKDINFELEEGKFYTLLGASGS
                     GKSTILNIIAGLLDATTGDIMLDGVRINDIPTNKRDVHTVFQSYALFPHMNVFENVAF
                     PLRLRKIDKKEIEQRVAEVLKMVQLEGYEKRSIRKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTDMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVATFIGESNILPGTMIEDYLVEFNGKRFEAVDGGMKPNEPVEV
                     VIRPEDLRITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIVGEEIG
                     LDFEPEDIHIMRLNETEEEFDARIEEYVEIEEQEAGLINAIEEERDEENKL"
     gene            33125..33931
                     /locus_tag="VVR63_000220"
     CDS             33125..33931
                     /locus_tag="VVR63_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6128284.1"
                     /translation="MKKTSSKLFVVPYMLWIALFVLAPLVLIFGQSFFNIEGQFSLEN
                     YKSYFASQNLTYLKMSFNSVLYAGIVTFVALLISYPTALFLTRLKHRQLWLMLIILPT
                     WINLLLKAYAFIGIFGQNGSINQFLEFIGIGSQQLLFTDFSFIFVASYIELPFMILPI
                     FNVLDDMDNNLINASYDLGATKWETFRHVIFPLSMNGVRSGVQSVFIPSLSLFMLTRL
                     IGGNRVITLGTAIEQNFLTNDNYGMGSTIGVILILTMFITMWVTKERRER"
     gene            33928..34701
                     /locus_tag="VVR63_000221"
     CDS             33928..34701
                     /locus_tag="VVR63_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6128285.1"
                     /translation="MKKFANLYLGLVFLVLYLPIFYLIGYAFNAGDDMNSFTGFSWTH
                     FETMFGDGRLMLILTQTFFLAFLSALIATIIGTFGAIYIYQSRKKYQEAFLSLNNILM
                     VAPDVMIGASFLILFTQLKFSLGFLTVLSSHVAFSIPIVVLMVLPRLKEMNGDMIHAA
                     YDLGASQFQMFKEIMLPYLTPSIITGYFMAFTYSLDDFAVTFFVTGNGFSTLSVEIYS
                     RARKGISLEINALSALVFLFSIILVVGYYFISREKEEQA"
     gene            34698..35768
                     /locus_tag="VVR63_000222"
     CDS             34698..35768
                     /locus_tag="VVR63_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU6128286.1"
                     /translation="MKKIYSFLAGIAAIILVLWGIATHLDSKINSRDSQKLVIYNWGD
                     YIDPELLTQFTEETGIQVQYETFDSNEAMYTKIKQGGTTYDIAIPSEYMINKMKDEDL
                     LVPLDYSKIEGIENIGPEFLNQSFDPGNKFSIPYFWGTLGIVYNETMVDEAPEHWDDL
                     WKPEYKNSIMLFDGAREVLGLGLNSLGYSLNSKDLQQLEETVDKLYKLTPNIKAIVAD
                     EMKGYMIQNNVAIGVTFSGEASQMLEKNENLRYVVPTEASNLWFDNMVIPKTVKNQNS
                     AYAFINFMLKPENALQNAEYVGYSTPNLPAKELLPEETKEDKAFYPDVETMKHLEVYE
                     KFDHKWTGKYSDLFLQFKMYRK"
     gene            36029..36268
                     /locus_tag="VVR63_000223"
     CDS             36029..36268
                     /locus_tag="VVR63_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000784186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6128287.1"
                     /translation="MKMSTFFKKSFWPTFMIVNQTVILFHLKDGLDRQYLTTESIYWV
                     IGTFIFGNILVAVFSNMKIWDKKKNGSKKKYILKK"
     gene            36543..37028
                     /locus_tag="VVR63_000224"
     CDS             36543..37028
                     /locus_tag="VVR63_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related family protein"
                     /protein_id="HEU6128288.1"
                     /translation="MKTFLVKQKFRLGGERFAIKNDRGEIAYQVEGSFFKIPKTFTIY
                     DAAGEQVSEISKEILTLLPRFEIQLRDGSSFVIRKKLTFWRDKYEFDNLGLRIEGNIW
                     DLNFKLLDDRDQLIAEIKKELFHLTSTYTVTVLEDAYADLVISLCVAIDYVEMLESQS
                     H"
     gene            37050..39668
                     /gene="alaS"
                     /locus_tag="VVR63_000225"
     CDS             37050..39668
                     /gene="alaS"
                     /locus_tag="VVR63_000225"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HEU6128289.1"
                     /translation="MKQLSSAQVRQMWLDFWATKAHSVEPSVSLVPVNDPTLLWINSG
                     VATLKKYFDGTIIPENPRITNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAITWAYELLTSPEWFDFPAEKLYMTYYPDDKDSYNRWIEVGVDPSHLIPIEDNFWEI
                     GAGPSGPDTEIFFDRGEAFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRS
                     EYKELPHKNIDTGAGLERLVAVIQGAKTNFETDLFMPIIREVEKLSGKVYDQDGDNMS
                     FKVIADHIRSLSFAIGDGALPGNEGRGYVLRRLLRRASMHGQKLGINEPFLYKLVPTV
                     GKIMESYYPEVLEKRDFIEKIVKSEEESFARTLHSGQHFAQGIVADLKEKGQSVIAGS
                     DVFKLYDTYGFPVELTEEIAEEAGMTVDREGFEAAMKEQQERARASAVKGGSMGMQNE
                     TLQNITVESVFNYNASQLSSKLVAIVADNAEVEAVSEGTASLIFAETSFYAEMGGQVA
                     DYGQILDESGKVVATVTNVQKAPNGQALHTVEVLAPLALNQEYTLAIDSNRRHRVMKN
                     HTATHLLHAALHNILGNHATQAGSLNEVEFLRFDFTHFQAVTAEELRAIEQQVNEKIW
                     EALEVKTVETDIDTAKEMGAMALFGEKYGKEVRVVTIGDYSIELCGGTHVGNTSEIGL
                     FKIVKEEGIGSGTRRILAVTGKEAFEAYREQEDALKAVAAILKAPQVKEVPHKVEGLQ
                     EQLRQLQKENAELKEKAAAAAAGDIFKDAKEVNGHRYIASQVSVSDAGALRTFADNWK
                     QKDYSDLLVLVAAIGDKVNVLVASKTKDLHAGNLVKELAPIIDGRGGGKPDMAMAGGS
                     NQAKIQELLDAVAGKL"
     gene            complement(39758..41212)
                     /locus_tag="VVR63_000226"
     CDS             complement(39758..41212)
                     /locus_tag="VVR63_000226"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HEU6128290.1"
                     /translation="MQNQTLMQYFEWYLPHDGQHWTRLAENAPHLAHLGISHVWMPPA
                     FKATNEKDVGYGVYDLFDLGEFNQKGTVRTKYGFKEDYLQAIQALKEQGIQPMADVVL
                     NHKAAADNREAFQVIEVDPVDRTVELGEPFTINGWTSFTFDGRQDTYNGFHWHWYHFT
                     GTDYDAKRSKSGIYLIQGDNKGWANEELVDNENGNYDYLMYADLDFKHPEVIQNIYDW
                     ADWFMETTGVAGFRLDAVKHIDSFFMRNFIRDMKEKYGDDFYVFGEFWNPDKEANLDY
                     LEKTEEHFDLVDVRLHQNLFEASQAGANYDLRGIFTDSLVELKPDKAVTFVDNHDTQR
                     GQALESTVEEWFKPAAYALILLRQDGLPCVFYGDYYGISGQYAQEDFKEILDRLLAIR
                     KDLAYGEQNDYFDHANCIGWVRSGAENQSPIAVLISNDQENSKSMFVGQEWTNQTFVD
                     LLGNHQGQVTIDEEGYGQFPVSARSVSVWAVNTI"
     gene            41391..42140
                     /locus_tag="VVR63_000227"
     CDS             41391..42140
                     /locus_tag="VVR63_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6128291.1"
                     /translation="MIEFQNVSKLYGDKEALSNLNLQIENGEIMGLIGHNGAGKSTTI
                     KSLVSIISPSSGRILVDGQELSENRLAIKRKIGYVADSPDLFLRLTANEFWELIASSY
                     DLTSSDLETSLARLLNVFDFAENRYQVIETLSHGMRQKVFVIGALLSAPDIWVLDEPL
                     TGLDPQAAFDLKQMMKEHAQKGKTVLFSTHVLEVAEQVCDRIAILKKGHLIYCGSVEN
                     LRKDHPDQFLESIYLSLAGRKEEVADASQGH"
     gene            42121..43755
                     /locus_tag="VVR63_000228"
     CDS             42121..43755
                     /locus_tag="VVR63_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6128292.1"
                     /translation="MRLKVIKKLVDINILYSSQEANLANLRKKQAKNPGKKVNVSARV
                     LSSYIFSSLLMLICFSNIAIHFPFEEMPIYFSSMVAILLVLAFSTSFTAFYNVFYESK
                     DLASYRPYAFKESEIIMAKGLSVLLPALTGIVPILAYFLALYISLAPSLWLGLPLMLL
                     SLTLLFVSVTLVTVVAVHFLAQTRVFRKYQSIFSNVMIGIGVLIPLIFIFFLQSTFGS
                     IVDKVRDIPFLLYPLHIFYKIAVEPFSTEALVGLLAWIGLTLFLLYLTKKKVLPRFYD
                     VILLNSEEKVKKERRSKERISTTKKGFFRMVLRYHLTLLGQGTGVITVLFTSAFLPYL
                     MMISLISKIRDSQIVPDIHPPYWLPLFFVGVFIAVVNNNITSLHSIALSLERENVDFL
                     KSLPFDFARYVKVKFWIIFAVQSFLPVLTLLGLSLYLGLSILSMIYLLVVWIIASVIL
                     SCHHYFKDVKNLSTNWSSITDLVNRSNGIVAIVLLFIYSAILMALVIGSIFLVQSLSP
                     ILAINLGVGALIVLLALAIFGYHYYLSRILAEIEKR"
     gene            44440..45603
                     /locus_tag="VVR63_000229"
     CDS             44440..45603
                     /locus_tag="VVR63_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HEU6128293.1"
                     /translation="MNRIRVSKRVEKKLAKGLVLLEASDLENVNLKDQEVEVQGQEGN
                     FLGTAYLSQQNKGLGWFVSKDKVAFNQTFFETLFRKAKEKRNAYYQDDLTTAFRLFNQ
                     EGDGFGGLTVDLYGDYAVFSWYNSYVYQIRQTISEAFRQVFPEVLGAYEKIRFKGFDY
                     ESAHVYGQEAPDFFTVLENGVLYQVFMNDGLMTGIFLDQHEVRGSLVDGLAMGKSLLN
                     MFSYTAAFSVAAAMGGASQTTSVDLAKRSRELSQAHFQANGLSTDEHRFIVMDVFEYF
                     KYAKRKDLTYDVIVLDPPSFARNKKQTFSVAKDYHKLISQSLEILNPGGIIIASTNAA
                     NVSRQKFTEQIDKGFAGRSYQILNKYGLPADFAYNKKDESSNYLKVISMKVSK"
     gene            45600..46277
                     /locus_tag="VVR63_000230"
     CDS             45600..46277
                     /locus_tag="VVR63_000230"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HEU6128294.1"
                     /translation="MKLIVSVMPRSLEEAQALGATRYLDADIIEWRADYLPKEAILQV
                     APAIFEKFAGRELVFTLRTRSEGGEIDLSPEEYIHLIKEVAQFYQPDYIDFEYYSYKD
                     VFEEMLDFPNLVLSYHNFQETPENMMEILSELTILNPKLVKVAVMAHTEQDVLDLMNY
                     TRGFKTLNPEQEYVTISMGKVGKVSRITADVTGSSWSFASLDEVSAPGQISLASMKKI
                     REILDEA"
     gene            46267..47121
                     /locus_tag="VVR63_000231"
     CDS             46267..47121
                     /locus_tag="VVR63_000231"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HEU6128295.1"
                     /translation="MKLDGYTRLAAVVANPIKHSISPFIHNRAFEATATNGAYVAWEI
                     EASDLAETVANIRRYQMFGINLSMPYKEQVIPYLDKLSDEARLIGAVNTVVNENGNLI
                     GYNTDGKGFFKCLPSFTISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEK
                     TRPYLDKLQEQTGFKVDLYALENVSELQARIVESDLLVNATSVGMDGQSSPVPESINL
                     PETILVADIIYQPFETPFLKWARSQGKPAVNGLGMLLYQAAEAFQLWTGKEMPTEEIW
                     QSLTEKYQ"
     gene            47140..48207
                     /locus_tag="VVR63_000232"
     CDS             47140..48207
                     /locus_tag="VVR63_000232"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HEU6128296.1"
                     /translation="MKIRIDIPHHPYDIQIEKGCLAQAGQWLRELWQPQKVVIVTDNH
                     VASLYAEKVKLSLEDAGFQVAVFDFLEGEERKNLTTVQKVYEFLVKQGLTRSDGIVAL
                     GGGVVGDLAGFVASTYMRGIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQP
                     DGVLIDPLVLETLGKRELIEGMGEVIKYGLIEDPELWALLTELDGSVESILEHAETLI
                     EHSCQVKRKMVVEDELDNGVRLYLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISK
                     VAEKKGLMPAGITQSITDMCQKFGLPVDYENWDVDKLYQALTHDKKARGNTLKLVLVP
                     ELGSATIHPVSLEEMKDYLVK"
     gene            48217..49383
                     /gene="aroC"
                     /locus_tag="VVR63_000233"
     CDS             48217..49383
                     /gene="aroC"
                     /locus_tag="VVR63_000233"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HEU6128297.1"
                     /translation="MRYLTAGESHGPRLTAIIEGIPAGLPLTAEDINGDLKRRQGGYG
                     RGGRMKIESDQVVFTSGVRHGKTTGAPITMDVVNKDHQKWLDIMSAEDIEDRLKSKRK
                     ITHPRPGHADLVGGIKYRFDDLRNSLERSSARETTMRVAVGAVAKRLLAELDMEIANH
                     VVVFGGKEIDVPENLTVAEIKQRAAQSEVSIVNQEREQEIKDYIDQIKRDGDTIGGVV
                     ETVVGGVPVGLGSYVQWDRKLDARLAQAVVSINAFKGVEFGLGFEAGYRKGSQVMDEI
                     LWSKEDGYTRRTNNLGGFEGGMTNGQPIVVRGVMKPIPTLYKPLMSVDIETHEPYKAT
                     VERSDPTALPAAGMVMEAVVATVLAQEILEKFSSDNLEELKEAVAKYRDYTKNY"
     gene            49393..50496
                     /locus_tag="VVR63_000234"
     CDS             49393..50496
                     /locus_tag="VVR63_000234"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HEU6128298.1"
                     /translation="MAKTIYIAGLGLIGASMALGIKRDHPDYEILGYNRSQASRDIAL
                     KEGMIDRATDDFASFAPLADVIILSLPIKQTIAFIKELANLDLREGVIISDAGSTKST
                     IVDAAEQYLAGKSVRFVGAHPMAGSHKTGAASADVNLFENAYYIFTPSSLTSQDTLKE
                     MKDLLSGLHARFIEIDAKEHDRVTSQISHFPHILASSLMEQTAVYAQEHEMARRFAAG
                     GFRDMTRIAESEPGMWTSILLSNSETILDRIEDFKERLEVIGQAISKGDEEQIWNFFN
                     QAREQRQTMEIHKRGGVDSSYDLYVDVPDEEDVILRILELLRGTSLVNIHINEENRED
                     IHGILQISFKNAQDLERAEHLITENTDYTVVIK"
     gene            50507..50845
                     /locus_tag="VVR63_000235"
     CDS             50507..50845
                     /locus_tag="VVR63_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HEU6128299.1"
                     /translation="MSNIYDSANELSRGLRGLPEYKAVKAAKDAIAADAEASKIFTEY
                     LAFQEEIQKLAHTGQMPDASFQAKMEGFGKQIQGNSLLSEFFTKQQQLAIYLSDIEKI
                     VFEPVSELLK"
     gene            50937..52220
                     /gene="aroA"
                     /locus_tag="VVR63_000236"
     CDS             50937..52220
                     /gene="aroA"
                     /locus_tag="VVR63_000236"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HEU6128300.1"
                     /translation="MKLKTNIRHLHGSIRVPGDKSISHRSIIFGSLAEGETKVYDILR
                     GEDVLSTMQVFRDLGVEIEDKDGVITIQGVGMAGLKAPQNALNMGNSGTSIRLISGVL
                     AGADFEVEMFGDDSLSKRPMDRVTLPLKKMGVSISGQTERDLPPLRLKGTKNLRPIHY
                     ELPIASAQVKSALMFAALQAKGESVIIEKECTRNHTEDMLKQFGGHLSVDGKKITVQG
                     PQKLTGQKVVVPGDISSAAFWLVAGLIVPNSRLVLQNVGINETRTGIIDVIRAMGGKL
                     EITEIDPVAKSSTLTVESSDLKGTEIGGALIPRLIDELPIIALLATQAQGVTVIKDAE
                     ELKVKETDRIQVVADALNSMGADITPTADGMIIKGKSALHGARVNTFGDHRIGMMTAI
                     AALLVADGEVELDRAEAINTSYPSFFDDLESLIHG"
     gene            52213..52689
                     /locus_tag="VVR63_000237"
     CDS             52213..52689
                     /locus_tag="VVR63_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HEU6128301.1"
                     /translation="MAKVLLGFMGAGKSTIARGLDPNYLDMDALIEKRLGMSIANFFA
                     EKGEAAFRQVESEVLADLLQTDQVVSTGGGVVISQRNRDLLKTNTDNIYLKADFETLY
                     QRIAADKDNQRPLFLNNSKEELVAIFQERQAWYEEVASRVLDVTKLSPEEIIEELR"
     gene            52686..53534
                     /gene="pheA"
                     /locus_tag="VVR63_000238"
     CDS             52686..53534
                     /gene="pheA"
                     /locus_tag="VVR63_000238"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HEU6128302.1"
                     /translation="MKIAYLGPKGSFSHHVVQIAFPHEELQAFANITDVIKAYEQGLV
                     DYSVVPVENSIEGSVHETLDYLFHQAHIQAVAEIVQPIHQQLMVVPGHTKIEKIFSHP
                     QALAQGKKFIDEQYPEAQIEVTASTAYAARFISEHPDQPFAAVAPRSSAEEYGLELIA
                     EDIQEMEANFTRFWVLGAEKPSIPLQAQTEKMSLALTLPDNLPGALYKALSTFAWRGI
                     DLTKIESRPLKTALGEYFFIIDVDYTDKDLVHFAQKELEAIGIQYKILGAYPIYPISD
                     HGKERR"
     gene            53531..54805
                     /gene="psr"
                     /locus_tag="VVR63_000239"
     CDS             53531..54805
                     /gene="psr"
                     /locus_tag="VVR63_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyisoprenyl-teichoic acid--peptidoglycan
                     teichoic acid transferase Psr"
                     /protein_id="HEU6128303.1"
                     /translation="MSKENPLSHHEQLRYDYLLKNIHYLNEREKNEFAYLQEKLTLAR
                     GNSSSSLEQEREEQVDLPSYANRSRSQSKSQALSFPPKKKRRKLRLKRIFMVIFSLLV
                     CVALAMVFMFLRGYQDASAKKTADARAAQVEVFNGQDTRDGVNILIMGTDGRIGQNSV
                     ETRTDSIMVLNVGGSDKKMKLVSFMRDNLVYIDGYSQVINGRKQTDNKLNVAYELGEQ
                     EGQKGAEMVRQVLKDNFDLDIKYYALVDFQAFATAIDTLFPDGVTIDAQFSTLNGRPL
                     TEATVGDDLYATETESPTQTIKVGKQQMNGSTLLNYARFRDDDEADYGRTKRQQQVLT
                     AILEQIKDPTKLFTGSEALGKVFAMTSTNVPYTFLLTNGLSVLDGAKNGIEKLTIPEL
                     GDWVDAYDVYGGLGLLVDQNKYQTKLAQMGLR"
     gene            55084..55929
                     /locus_tag="VVR63_000240"
     CDS             55084..55929
                     /locus_tag="VVR63_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEU6128304.1"
                     /translation="MNNMTDLKAIQARSLEMAEYFVAFCKEHDLLCYLCGGGAIGALR
                     NKGFIPWDDDLDFFMPRKDYEKLAELWPRYADERYFLSKSHKDFVDRNLFITIRDKET
                     TCIKPYQQDLDLPHGLALDVLPLDYYPKNPAERKKQVRWALIYSLFCAQTIPEKHGAL
                     MKWGSRILLGLTPKSLCYRIWKKAEKEMTKYDLADCDGITELCSGPGYMRNKYPITSF
                     EDNLFLPFEGTEMPIPIGYDVYLRTAFGDYMTPPPADKQVPHHDAVIADMDKSYTEYK
                     GEYGG"
     gene            55919..57022
                     /locus_tag="VVR63_000241"
     CDS             55919..57022
                     /locus_tag="VVR63_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEU6128305.1"
                     /translation="MVAKKKILFFMWSFSLGGGAEKILSTIVSNLDPEKYDIDILEME
                     HFDKGYESVPKHVRILKSLQDYRQTRWLRAFLWRMRIYFPRLARRLLVKDDYDVEVSF
                     TIMNPPLLFSKRREVKKISWIHGSIEELLKDSSKRESHRSQLDAANTIVGISKKTSNS
                     IKEVYPDYTSKLQTIYNGYDFQTILEKSQEKIDIEIAPQSICTIGRIEENKGSDRVVE
                     VIRLLHQEGKNYHLYFIGAGDMEEELKKRVKEYGIEDYVHFLGYQKNPYQYLSQTKVL
                     LSMSKQEGFPGVYVEALSLGLPFISTNVGGAEELSQEGRFGQIIESNQEAAQAITNYM
                     TSASNFDVDEASQFIQQFTITKQIEQVEKLLEE"
     gene            57024..58010
                     /locus_tag="VVR63_000242"
     CDS             57024..58010
                     /locus_tag="VVR63_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000446977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU6128306.1"
                     /translation="METALISVIVPVYNVAQYLEKSIASIQKQTYQNLEIILVDDGAT
                     DESGRLCDSIAEQDDRVSVLHKKNEGLSQARNDGMKQAHGDYLIFIDSDDYIHPEMIQ
                     SLYEQLVQEDADVSSCGVMNVYANDESPQSANQDDYFVCDSQTFLKEYLIGEKIPGTI
                     CNKLIKRQIATALSFPKGLIYEDAYYHFDLIKLAKKYVVNTKPYYYYFHRGDSITTKP
                     YAEKDLAYIDIYQKFYNEVVKNYPDLKEVAFFRLAYAHFFILDKMLLDDQYKQFEAYS
                     QIHRFLKGHAFAISRNPIFRKGRRISALALFINISLYRFLLLKNIEKSKKLH"
     gene            58026..59459
                     /locus_tag="VVR63_000243"
     CDS             58026..59459
                     /locus_tag="VVR63_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy family
                     protein"
                     /protein_id="HEU6128307.1"
                     /translation="MIDGKRLLFSLTIVSYALTLVSGIVYLFNNNNVSLLSTLLFLLV
                     SSLIACWNDIKYYLIHFIFYLTIFVFLVSRPTIDYFRDGALDTYHPIAYRFAFIVVMV
                     SILGLTTGGILARYFIARKKIKVANIGNSLKEVYIKRLRFVSLGVFLLTYPFYFIRLF
                     ERLLYRLQTSYYAYYANFESKLPYFTYILSTFTVYAMCMYLATKPKKLQATAVLVSFI
                     AANTIHLAIGTRNPFILSILFAFVYYFMREQTEKGKWIGFKEKLAIFVGSPILMLAMG
                     VLNYVRDNVQVSHTGFWDILLDFIYKQGTSFGVLARGFLFNSSLPYRDFRNFTFGPVL
                     DYFARGSLGAIFGGKAFEHTTNSVELAIDSNSYAHNLSYLVLNKEYLKGHGIGSSYIM
                     ELYTDYGMIGVFLLSFLLGVLFIAMLQVAYRSRTILFALSLLILNNLFFMPRSSFSES
                     FFNLFTMQFWGIVLVIIFVAKMLTKEN"
     gene            59488..60522
                     /locus_tag="VVR63_000244"
     CDS             59488..60522
                     /locus_tag="VVR63_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HEU6128308.1"
                     /translation="MFEHYSVADLFANLYKKRKANILALIALFALIAVPFTIKAVRNK
                     NTVKDTTSYSTYLIYKITPPKESAKTILNHQIGGYSDFYGKLIDGNLNGAYLFNDVEP
                     SELKKIASELDTTETTLKNSTNDYWWKKLTVYYMIDDAGVGVKILTSSKDANDLLEKK
                     IDGLIEKFKHAYANVKIEKLETINSKELNANGETALGLNVKNLILRLVVIGVVCVILV
                     VMGNVLVYLFNPTINRVGDFSQYQIDFVTEITTIANLADVLSYKNTGQELTIVSSNKA
                     ILDKLKQSQEALKGMHFVDLQDVSSLLERDTVLLVEEYGVTRYKKFEQSLQILRNLNR
                     SILGVATFKL"
     gene            60722..61459
                     /gene="mecA"
                     /locus_tag="VVR63_000245"
     CDS             60722..61459
                     /gene="mecA"
                     /locus_tag="VVR63_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HEU6128309.1"
                     /translation="MKMKQISDTTLKITMSLEDLMDRGMEIADFLVPQEKTEEFFYAI
                     LDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKIDQNLDFEDLSDLPDMEELAQMS
                     PDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQAEQEAESKKEPYIYYILSFA
                     KLADLVVFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFADDS
                     DISRSVLQEYGQVLMSHDAVLNLQKIG"
     gene            61610..62896
                     /locus_tag="VVR63_000246"
     CDS             61610..62896
                     /locus_tag="VVR63_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HEU6128310.1"
                     /translation="MTVKIALLGFGTVASGVPFLLKENGGKINQSAHSDIKVAKVLVK
                     DEDEKNRLLAAGNDFNFVTNVDDILSDQDITIVVELMGRIEPAKTFITRALEAGKHVV
                     TANKDLLAVHGAELLEIAQANKVALYYEAAVAGGIPILRTLANSLASDKITRVLGVVN
                     GTSNFMVTKMVEEGWSYDDALAEAQRLGFAESDPTNDVDGIDAAYKMVILSQFAFGMK
                     IAFDDVAHKGIRNITPEDVAVAQEFGYVVKLVGSIEETSSGIAAEVTPTFLPKAHPLA
                     SVNGVMNAVFVESIGIGESMYYGPGAGQKPTATSVVADIVRIVRRLNDGTIGKDFNEY
                     SRDLVLANPEDVKANYYFSILAPDSKGQVLKLAEIFNAQDISFKQILQDGKEGDKARV
                     VIITHKINKAQLENVSAELKKVSEFDLLNTFKVLGE"
     gene            62898..63767
                     /locus_tag="VVR63_000247"
     CDS             62898..63767
                     /locus_tag="VVR63_000247"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000692406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HEU6128311.1"
                     /translation="MKIIVPATSANIGPGFDSVGVAVTKYLQIEVCEERDEWLIEHQI
                     GKWIPHDERNLLLKIALQIVPDLQPRRLKMTSDVPLARGLGSSSSVIVAGIELANQLG
                     QLNLSDHEKLQLATKIEGHPDNVAPAIYGNLVIASSVEGQVSAIVADFPECDFLAYIP
                     NYELRTRDSRSVLPKKLSYKEAVAASSIANVAVAALLAGDMVTAGQAIEGDLFHERYR
                     QDLVREFAMIKQVTKENGAYATYLSGAGPTVMVLASHDKMPTIKAELEKQPFKGKLHD
                     LRVDTQGVRVEAK"
     gene            64017..64955
                     /gene="msrB"
                     /locus_tag="VVR63_000248"
     CDS             64017..64955
                     /gene="msrB"
                     /locus_tag="VVR63_000248"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEU6128312.1"
                     /translation="MAEIYLAGGCFWGLEEYFSRISGVLETSVGYANGQVETTNYQLL
                     KETDHAETVQVIYDEKEVSLREILLYYFRVIDPLSINQQGNDRGRQYRTGIYYQDEAD
                     LPAIYTVVQEQERMLGRKIAVEVEQLRHYILAEDYHQDYLRKNPSGYCHIDVTDADKP
                     LIDAANYEKPSQEVLKASLSEESYRVTQEAATEAPFTNAYDQTFEEGIYVDITTGEPL
                     FFAKDKFASGCGWPSFSRPISKELIHYYKDLSHGMERIEVRSRSGSAHLGHVFTDGPR
                     ELGGLRYCINSASLRFVAKDEMEKAGYGYLLPYLNK"
     gene            65013..66737
                     /locus_tag="VVR63_000249"
     CDS             65013..66737
                     /locus_tag="VVR63_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6128313.1"
                     /translation="MKYLLSYFKPYIKESILAPLFKLLEAVFELLVPMVIAGIVDQSL
                     PQGDQGHLWMQIGLLLIFAVIGVLVALIAQFYSAKAAVGFAKELTNDLYRHILSLPKD
                     SRDRLTTSSLVTRLTSDTYQIQTGINQFLRLFLRAPIIVFGAIFMAYRISAELTFWFL
                     VMVAILTIVIVGLSRLVNPLYSSLRKKTDQLVQETRQQLQGMRVIRAFGQEKRELQIF
                     QTLNQVYARLQEKTGFWSSLLTPLTYLIVNGTLLVIIWQGYISIQGGVLSQGALIALI
                     NYLLQILVELVKLAMLINSLNQSYISAKRIEEVFVEAPEDIHSELEQKQATRDKVLQV
                     QELTFTYPDAAQPSLRDISFDMTQGQILGIIGGTGSGKSSLIQLILGLYPVNKGRIDL
                     YLDGLSPLNLEQWRSWIAYVPQKVELFKGTIRSNLTLGLNQEVTDQELWQALEIAQAK
                     DFVSDKEGLLDALVEAGGRNFSGGQKQRLSIARAVLRQAPFLILDDATSALDTITESK
                     LLKAIREDLPNMSLILISQRTSTLQMADQILLLEKGELLAVGKHDDLMKSSQVYREIN
                     ASQHGKED"
     gene            66739..68487
                     /locus_tag="VVR63_000250"
     CDS             66739..68487
                     /locus_tag="VVR63_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6128314.1"
                     /translation="MKRQTVNQTLKRLAVDLASHPFFLFLAFLGTIAQVGLSIYLPIL
                     IGQVIDQVLVAGSSPVFWQIFLQMLLVVIGNTLVQWANPLLYNRLIFSYTRDLRERII
                     HKLHRLPIAFVDRQGSGEMVSRVTTDIEQLAAGLTMIFNQFFIGVLMILVSILAMLQI
                     HLLMTLLVLLLTPLSMVISRFIAKRSYHLFQKQTETRGIQTQLIEESLSQQTIIQSFN
                     AQTEFIQRLREAHDNYSGYSQSAIFYSSTVNPSTRFVNALIYALLAGVGAYRIMMGST
                     LTVGRLVTFLNYVQQYTKPFNDISSVLAELQSALACVERIYGVLDSPEVAETGKEVLT
                     SDQVKGAISFKHVSFGYHPEKILIKDLSIDIPAGSKVAIVGPTGAGKSTLINLLMRFY
                     PISSGDILLDGQSIYDYTRASLRQQFGMVLQETWLTQGTIHDNIAFGNLEASREQVIA
                     AAKAANADFFIQQLPQGYDTKLENAGESLSVGQAQLLTIARVFLAIPKILILDEATSS
                     IDTRTEVLVQDAFAKLMKGRTSFIIAHRLSTIQDADLILVLVDGDIVEYGNHQELMDR
                     KGKYYQMQKAAAFSSE"
BASE COUNT        20008 a        12730 c        15459 g        20468 t
ORIGIN      
        1 tggacgagat gtggaaggtt gcccaacgtg aattggcaac aggtttctac tacggtatac
       61 catctgaaaa tgagcagttg tttggtgctc gccgtaaaat tcctgagtac aagtttgtcg
      121 ctgaagtggt ttcttatgat gatgcggtac aaacagcaac cattcgtcaa cgaaacgtca
      181 ttaacgaagg ggaccaagtt gagttttatg gtccaggttt ccgtcatttt gaaacctata
      241 ttgaagattt gcatgatgcc aaaggaaata aaatcgaccg cgctccaaat ccaatggaac
      301 tattgactat taaagtccca caacccgttc aatcaggaga catggttcgt gcattaaaag
      361 aaggactcat caatttttat aaggaagatg gaaccagcgt cacagttcga gcttaagaaa
      421 ggaaaaggaa atgatagagg cacagggttt cttagtggat aagcaaacaa gatgcattca
      481 ttaccatagc aagctggata ttattgcttt acaatgctat gattgtaaaa agtattatgc
      541 ttgttatcgg tgtcatgatt cattagaaaa tcaccctttt gagccttatc ccttatcttt
      601 gatacaggat aagcctattt tatgtggtgt ttgtctaaaa ctattaacat ataagcaata
      661 taaagaaagc ttaagttgcc tcttttgttt ttctcgcttt aatccaggtt gccaaaatca
      721 taaggaacgc tattttaaat agcaaatcat ctagttttga agtaggagaa aactcaattc
      781 caagagaaaa tgaagtaaat cttcccacaa taaaacgcat aatatcaaga ttgttcaata
      841 cctgatacta tgcgttttta agattttaaa gacttttttc ctagcccctt tttactttat
      901 ctggtatttt gactacttgt taaaactggg gtaattttcg actgtttaac agttattatg
      961 caaagtctaa aaggttagaa ttgtcaaaac aatccgtcta gagtatgcgt gatgccaacc
     1021 gtggtggatg ttctcagtca tgccgttgga agtacgacct ttacgatatg ccatttggga
     1081 aagaacgtaa gagtttgcag ggtgagattc cagaagaatt ttcaatgtca gccgttgata
     1141 tgtctatgat tgaccatatc tcagatatga ttgaaaatgg tgtggacagt ctaaaaatcg
     1201 aaggacgtat ggagtctatt cactatgtat caacagtaac caactgctac aaggcggctg
     1261 tggatgccta tcttgaaagt cctgaaaagt ttgaagctat caaacaagac ttggtggacg
     1321 agatgtggaa ggttgcccaa cgtgaactgg ctacaggatt ttactatggt acaccatctg
     1381 aaaatgagca gttgtttggt gctcgtcgta aaatccctga gtacaagttt gtcgctgaag
     1441 tggtttctta tgatgatgcg acacaaacag caaccattcg tcaacggaac gtcattaacg
     1501 aaggggacca agttgagttt tatggtccag gtttccgtca ttttgaaacc tatattgaag
     1561 atttgcatga tgccaaaggc aataaaatcg accgcgctcc aaatccaatg gaactattga
     1621 ctattaaagt cccacaactt gttcaagctg gagacatggt tcgagctctt aaagaggggc
     1681 ttatcaatct ttataaggaa gatggaacca gcgtcacagt tcgtgcttaa tgtagttgtt
     1741 tagttttaaa aaattatgca aagctccata tacaacactt aaacgagatt aaagaatggc
     1801 gaaatccctt gatgcgcaag agattagctg tcctttttta ttttttaagt gataaagtcg
     1861 gagcttaggt attaaagcct atcaaattaa acaaagaagc gatgtcttag atattttgaa
     1921 aaaaattaat aagcagaaaa ctctctatta ttttgttgta gagagttttt tgttaataaa
     1981 attttacaaa atgacattta tatattgcat taagttagat atatgatata atattgttaa
     2041 aaagaggcgc aactttttaa actcaataag aatcaaagag caaaccatga atattaatgg
     2101 aggaataaaa aatgtaagtt ataaatgtaa gtaagcatta tggtcattca atcattctca
     2161 aagatataaa ttttgcactt aacaagggtg aaattgttgg tctagtaggg agaaatggag
     2221 ttggtaagag tacgttgatg aaaattcttg ttcaaaataa tcaaccgact tcaggtaata
     2281 ttataaacag tgataatgtt gggtatttaa tcgaagaacc aaaattattt ttatctaaaa
     2341 caggtttaga gaatttaaaa tatttgtcaa atttatatgg tgttgactac aatcaagaaa
     2401 gatttagaag tttgatccaa gagttagatt tgactcagtc tattaataaa aaagtaaaga
     2461 cctattcttt gggtacaaaa caaaaattag ctttgcttct aactctcgtt acggaacctg
     2521 atatattgat tttagatgaa ccgactaatg gtttagatat tgaatcatca caaatagttt
     2581 tagcggttct aaaaaaaatt agctttaaat gaaaacgtgg gaattttaat atcgagtcat
     2641 aaattagaag acattgaaga aatttgtgag agggttcttt tcttggagag cgggcttttg
     2701 acatttcaaa aagtaggaaa agatagtcat aatttcttgt ttgagatagc tttttcatca
     2761 gctacagata gagacatttt cattaccaaa caagaatttg gggatattgt tcaggaagag
     2821 ggattgagaa ttactatgtc tgggaatatt caaaatagtg agctttttaa attttttaac
     2881 gaaaactcta ttaaagtagt tgattttgaa actaaaaaag agacgcttaa agatatttac
     2941 ctaaatcgtt caaaataaag gaaggttata atcatgaaat taaataaaca gaagaatcgg
     3001 atgatttacg tcttgtctaa ttttctatat gccatctcag tttccattat ttatgctttg
     3061 aatggcattg tgttactagt catagtaagt aaattgggta ttccaggtga tttaggatta
     3121 gattttatag tagctattgt agtcaataca attttgttag tcctgtttta ttttctatta
     3181 tcttacattt tttatttata caaattgaaa agtggcttgg tatttggtat tttagtagct
     3241 ttactactct ttatccctaa tatattaaat acgatgatga tgaatactag taatgatttg
     3301 tttatcaaag caattgaact tcttcctttt tattctttac ctgtatttgt ggcttcaaat
     3361 acgatgtcta ttagtcagta tcttgtggta atcactacaa tcattttatt gtactttttc
     3421 actctcaaga aaagcaagaa gtattcattt tagtttcatt tagtattatt ttgcatacct
     3481 aaaatacaat aaaaaaatca gtcatcttgg tatgctcctg ctttcactat tcaacacgtt
     3541 tttgacttat actaggctca tttccaaaag cattatataa tagtgatatg aaaccaacta
     3601 aactaaacaa gaaatataag caataaaaac tcgtttaaaa gatcctacta aagctaatac
     3661 taaataaaaa taaaagagta aactaggaag tttatttcaa acaacctaaa atactgattt
     3721 tcggctgaag ataatactgg agtgcaaatt aatggggtta taataaatag ctgatagctt
     3781 gtgttggttt tggatttttt aagagtagat gagtattaaa actataagga ggacgaaggt
     3841 ggctaaaaat ttaaaattaa aattagctcg ggtagagcgt gatttaacac aaggtcaatt
     3901 ggcagaggct gtcggggtga cacgccagac tattggttta atagaggcgg gaaaatacaa
     3961 tcccagtctc tcgctctgcc agtctatttg cagatgttta gggaaaaccc tagaccaact
     4021 attttgggag gaagaagatg aaaaatagat tttattatta tcaattacta gacgaaagag
     4081 aagaacaact gttcaataaa gcgggctctg aaagtttcta tatctgcatt gctttgtcgc
     4141 tcctatctta tatcatttca gtattagcac caagcctttt taattctaat atgctgctaa
     4201 tcgttatcat catagggaca ttttactttt tcaatcgtgc ccgttatctg ggagtgacct
     4261 actatagtcg ttttcatttt acgattttgg gttgtttttt cctaaccttg gctattacgg
     4321 ctcttttgat gttgcagaat tatcaattca acatagaaat ttatcagcac aatcctttga
     4381 attttaaata cctgtctgct tgggtcatta cttatatcat ttaccttccg tggatcttta
     4441 ttggcaatct tggtcttaag agctatggcg aatgggctca gaaaaaattt gaacaagata
     4501 tggatgaatt ggagagtgga gaatagcttg ttactctttt ctcaatccag ctaaaatgtg
     4561 atataatagt actaatttat tggaatacat gaaagttctt gaaaattttc atgggtttct
     4621 agctaaggaa gtaggaaaag tatgtatcca gatgatagtt tgacattgca cacggacttg
     4681 taccagatca acatgatgca ggtttacttt gaccaaggga ttcacaataa gaaggcggtc
     4741 tttgaggtgt atttccgcca acagcctttt aagaacggct atgcggtttt tgcaggtttg
     4801 gaaagaattg tgaactatct tgaagacttg cgtttttcag atagtgatat agcctatttg
     4861 gagtcgcttg gttatcatgg ggcgttcttg gattaccttc gcaatttcaa gttggagttg
     4921 accgttcgtt ctgcccaaga aggggatttg gtttttgcta atgaaccgat tgtgcaggtg
     4981 gaaggacctc tagcccaatg tcagttggtc gaaacggctc ttttgaacat cgtcaactac
     5041 cagaccttgg tggcgacgaa ggcagctcgt attcgttcgg ttatcgaaga tgaacccttg
     5101 atggagtttg ggacacgtcg ggctcaagaa atggatgcgg ccatctgggg aacacgcgca
     5161 gctgtgattg gtggcgccaa tggaaccagc aacgtgcgtg cgggtaagct ctttgacatt
     5221 cctgttttgg gaacccatgc ccatgccttg gtacaggttt atggcaatga ctatgaagct
     5281 ttcaaggctt acgctgcgac ccacaaaaat tgtgtctttc ttgtggatac ctatgacacc
     5341 cttcgcatcg gtgtaccagc tgccattcag gtggcgcgtg agctgggtga tcagattaac
     5401 tttatgggtg tgcggattga ctctggggat attgcctaca tttctaagaa agtccgtcag
     5461 caactggacg aggctggatt tacagaggct aagatttatg cttctaatga tttggacgaa
     5521 aatactatcc tcaatctcaa gatgcaaaag gccaagattg atgtctgggg cgtgggtacc
     5581 aagctgatta cagcttatga ccagccagct cttggtgcag tttacaagat tgttgcaatc
     5641 gaagatgaaa ctggtcagat gcgcaatacg attaagctgt ctaataatgc tgaaaaagtt
     5701 tctacgccag gtaagaagca ggtgtggcgc attaccagtc gtgaaaaagg caagtcagaa
     5761 ggcgactata tcacttatga tggtgtggat attagcgaca tgacagaaat caagatgttc
     5821 catccgacct atacatacat caagaagacg gttcgtaatt ttgatgccgt tcctctcttg
     5881 gtggatatct tcaaagaagg aatattagtt tacaacttgc ctagtttgac tgacattcag
     5941 gattatgccc gtaaggaatt tgacaagttg tgggatgagt ataagcgtgt gctcaatccg
     6001 cagcactatc cagtggattt ggcgcgtgat gtatggcaag ataagatgga cttgattgat
     6061 aagatgcgca aggaagccct tggtgaagga gaagaagaat gagtttgcaa gaaacgatta
     6121 tccaagagct gggtgtcaaa ccagtgattg atgcccagga agaaatccgt cgttctattg
     6181 atttcttaaa aagatatctg aaaaaacatc ccttcctaaa aacctttgta ctagggattt
     6241 ctgggggaca agactcaacc ttggcaggac gtttggcgca attagctatg gaagaactgc
     6301 gagctgaaac gggagacgat agctacaaat ttatcgctgt ccgcctgcca tacggagtgc
     6361 aagctgatga agcagatgct caaaaagccc tagccttcat ccagccagat gtcagcttgg
     6421 ttgtgaatat caaggaatca gctgatgcca tgacagctgc agttgaagcg acaggtagtc
     6481 ctgtttcaga cttcaacaag gggaatatca aggcacgttg ccgtatgatt gctcagtatg
     6541 cccttgctgg ttcccatagc ggagcggtca ttggaacaga ccacgccgcg gaaaatatca
     6601 caggtttctt taccaagttt ggtgacggcg gtgcggatat tctccctctt taccgcctca
     6661 ataaacgcca aggaaaacag ctcttgcaga aacttggcgc agagccagcc ctttatgaaa
     6721 aaatcccaac ggcagaccta gaagaagata aaccaggcct agctgacgaa gtcgcacttg
     6781 gagtcaccta cgcagagatt gacgactacc tagaaggcaa aacaatcagc ccagaagctc
     6841 aagcgaccat tgaaaactgg tggcacaaag gccaacacaa acgccactta cccatcaccg
     6901 tatttgatga cttttgggag taaaaaggtc cgggggacct ttttagcttc ttgccctgaa
     6961 attaaaaagc aagaaaaacc tccactggag gttttcagcc tctcatcttg aaataagaaa
     7021 gtgagagaag gtccggggga tcttgaaccc cgagtttaga aataagaaaa tgaggcagat
     7081 tcggtaactc gaagagttcg atttcatcgt cttacccctg caacgatgac taggtttgaa
     7141 aaagattgct agagcgcatt tcaaaccagg cagcgactgc gtcaagaaat tagaagacaa
     7201 actcgttttc tagctgttac tgagttgagt ctttttacta cgagcataga aataaggaag
     7261 tgaggtagca tcatgaaatc tatcggtacg caaatattac agacagaacg tttgatttta
     7321 agaagatttg tggagagtga tgcagaagct atgtttcaaa attgggcttc atccgctgag
     7381 aatctgacct atgttacctg ggatccccat cctgatgtcg aaatcactcg aaactcgatt
     7441 cgcaattggg ttgcttccta tactaatctc aactattaca aatgggccat ttgtctaaaa
     7501 gaaaacccag agcaagtgat aggagatatc agcatcgtta agatagacga ggctgattta
     7561 agctgtgaaa tcggctatgt gctaggcaag gcttactggg gacatggtat gatgacagag
     7621 gccttgaaag ctgtcttgga cttttgtttt actcaagtag gttttcaaaa ggtcagagca
     7681 cgttatgcca gtctcaaccc agcttcaggc cgtgtcatgg aaaaggctgg aatgtcctat
     7741 ctacaaacca ttgttaatgg tgtagagaga aaaggctatc ttgcggatct tatttattat
     7801 ggtataagta gggaagaatg ttgaattcta ttttctgttt ctatcgaagt caactattta
     7861 ttgtaaatat aataattagc attccaagtt tatttgcaat tttaaaatag catattgatt
     7921 agtacaagac agatgctcta gttccttctt taatctggtt tagtattagt taaaaaatcg
     7981 cttgaagctt gtaactaaga gggagctaat cgactagatt ctccagccga acaggtggta
     8041 atgtactttt tatagtgtaa tcctagctgt tgttaaattt aaaatagaat cctctatcga
     8101 gttagggaat taaattcaac caattttatt tatgtttttc tatcaaatta tctaatatta
     8161 aaatagtctc attctgatga gaaaactatt ctatttatac tgcatagttg tataaggaat
     8221 gatgaaagat gagtgaaaat tatcaagttg gaatgtttgt atctaaatat attagcatgt
     8281 atttagataa gatgtctgca atcctttata tatgagattg attacgatat agttaaagtg
     8341 ttagttcaat aatcaatata tcattctaag tctattttat atataaagta tattgtttaa
     8401 cgtttgatag aaaagatgct atactagaag taggatgtaa tggcaaaatc taatactaat
     8461 aagcgctatg caatacgtaa actcggaaag atttttggtt ctgcggtaat cgggctaact
     8521 ttatttttag gaggaatctg aatacaagtt ttgttcatgc tgctgatggg attcaatatg
     8581 tcagagatga tactagagat aaagaagagg gaatagagta tgatgacgct gacaatgggg
     8641 atattattgt aaaagtagcg actaaaccta aggtagtaac caagaaaatt tcaagtacgc
     8701 gaattcgtta tgaaaaagat gaaacaaaag accgtagtga aaatcctgtt acaattgatg
     8761 gagaggatgg ctatgtaact acgacaagga cctacgatgt taatccagag actggtcatg
     8821 ttaccgaaca ggttactgtt gatagaaaag aagccacgga tacagttatc aaagttccag
     8881 ctaaaagcaa ggttgaagaa gtttttgttc catttgctac taaatatgaa gcagacaatg
     8941 acctttctgc aggacaggag caagagatta ctctaggaaa gaatgggaaa acagttacaa
     9001 cgataactta tgatgtagat ggaaagagtg gacaagtaac tgagagtact ttaagtcaaa
     9061 aagaagactc tcaaacaaga gttgttaaaa aaggaaccaa gccccaagtt cttgtccaag
     9121 aaatttcaat cgaaacagaa tatctcgatg gcccaactct tgataaaagt caagaagtag
     9181 aagaagtagg agaaattggt aaattactct tactacaatc tatactgtag atgaacgtga
     9241 tggaacaatt gaagaaacta cttctcgtca aattactaaa gagatggtaa aaagacgtat
     9301 aaggagaggg acgagagaac ctgaaaaagt tgttgttcct gagcaatcat ctattccttc
     9361 gtatcctgta tctgttacat ctaaccaagg aacagatgta gcagtagaac cagctaaagc
     9421 agttgctcca acaacaggct ggaaacaaga aaatggtatg tggtattttt ataatactga
     9481 tggttccatg gcaacaggtt gggtacaagt taatggttca tggtactacc tcaacagcaa
     9541 cggttctatg aaagtcaatc aatggttcca agttggtggt aaatggtatt atgtaaatac
     9601 atcgggtgag ttagcggtca atacaagtat agatggctat agagtcaatg ataatggtga
     9661 atgggtgcgt taacagattc ctccctgcga caaaattgat aatagtatgt ctgaatatat
     9721 aattatatat aaaaagctat agataaggtc atcttatagc gactataaaa aagtgaacaa
     9781 gcctagtctt ctgtacatta gaattcagat ttgttcactt tttgtttaat actcaatgaa
     9841 aatcaaagag caaactagaa aactagtcgc aggttgctca aagtactgct ttgaggttgt
     9901 agatagaact gacgaagtca gtcacatata taatccaagg tgacgttgac gcggtttgaa
     9961 gagatttttg aagagtataa gtctttgatt ttgagactaa ggagagtcag ggtcaaagta
    10021 gtgaatgatt ctgaaataac tcataatagt ctcttgagag gacagataag agtaacaaat
    10081 atggtgctac tcatgtgtct tgcattttga tttacaaaca gcgaagaaaa tataggaagc
    10141 tgaaataaaa tatagatgaa tcaatttgga gagtcaacgc aatctatggc aatattttcg
    10201 aagctagggg gaagcatttt aatttcaatg tactaggcgt cttctacagc tagctagagt
    10261 ttcaattgta gatgttcttt gaaataatat cttagcgatt tattggtatt agaagaatta
    10321 gagaaattct ttctcaataa ataaacatgg cgtcaccaaa actgaagaag cggtagtgtt
    10381 cttggatggc atggtggtag gcatctaaga ctaattcacg gcctgcaaag gcagaaacca
    10441 acatgaccag agttgatttt ggcagatgga agttggttga gaaggcatcc acgaccttcc
    10501 actcataccc aggtttgata aagatattgg tccaaccaga atctgcttgg atttgcccat
    10561 caaacttgga accaatagtt tccaaggtgc ggatagaagt ggttccgaca gcgatgacgc
    10621 gaccaccatt ttctttgaca gagcgaaggg tggcagcagc ttcctcagaa agttgataga
    10681 actctgagtg catttcgtgt tcgtccagat tatccacaga aacaggtcta aaggttccga
    10741 gtccgacatg gagagtcaga tagactagat gaacaccctt agcttggatt tctgccagca
    10801 gttctttggt gaagtgaaga ccagcagtcg gtgctgcagc agagccgctt tccttggcgt
    10861 agacggtttg ataacgttca cggtcatcta atttttcgtg gatataaggt ggcagaggca
    10921 tttctcccag actttccaag acttctagga aaattccttg gtattcaaag cggacaatgc
    10981 gtcccccgtg ggtcaattct tctgtaacga cagcgctgag gcggccatca ccaaagctga
    11041 tacgagtacc gaccttgagg cgtttggcag gtttagccag aacttcccac tcgtctccac
    11101 tagtgttctt aaggaggaga agttccacat gacctcctgt ctccactttt tgaccataga
    11161 ggcgggcagg gagaactcgg gtgtcgttca tgacaagggc atcaccaggt tccagcatat
    11221 caataataga gtggaagtgt ttatcttgca tttctcctgt ctcacggttg acgatgagga
    11281 gtttggaggc atcacgtttt tcaaggggcg tttgggcaat caattcctct ggcaagtgga
    11341 aatcaaaatc agctgtattc atatatttgt tcattctttc taagttctaa tcctatccat
    11401 tataacacgt ttcaagtttg gacgctcttt ttttagaaat taaatcgttt tcacttgaca
    11461 aaaattggtc tataccatat aataaatata gacagaaatg gaggatgaaa agatgaaagt
    11521 tattaaagtt gaaaaccaag ttcaaggtgg aaaagttgct tttgagattt tgaaggaaaa
    11581 attggctaat ggagctcaaa ctctaggact tgcgacagga agtagcccac ttgaatttta
    11641 caaggaaatt gttgagagtg accttgattt ttcaaatcta accagtgtca accttgatga
    11701 gtatgtgggc cttgatgggg acaatccaca atcttatcgt tacttcatgc aagaaaactt
    11761 gttcaaccaa aaaccattta aagaaagttt cttgcctcgt ggtgttaagg acaatgctga
    11821 agctgaagtt gaacgctaca accaaatttt ggctgaccat ccagttgacc tccaaatctt
    11881 gggaatcggt cgcaatgggc atatcggctt taatgagcct ggtactccat ttgacagtca
    11941 aacgcatcta gtagaacttg accagtctac tatcgaagcc aatgcacgct tctttgccaa
    12001 gattgaagac gtcccaaccc aagctatttc aatggggatt aaaaacattt tggatgccaa
    12061 gtctattatt ctttttgctt acggtgagtc gaaagcagaa gccattgccg gaacagtatc
    12121 tggcccagtg actgagaacc tacctgcaag tagccttcaa aatcaccctg atgtaaccat
    12181 catcgcagat gctgaagcgc ttagcttact cgaaaaataa aaaagcaatg ttctattgaa
    12241 cgctttcaac tcttgtataa atggaagaaa aaatcaaaat taaaccgcat ttttgcttga
    12301 caattattcc ttttacgtgt agaatgaaat agatattgaa cttgaaggga gtgaaaaaaa
    12361 tgtctaaaac agtagtacgt aagaatgaat ctcttgacga cgcacttcgc cgtttcaaac
    12421 gtgcggttac taaagctggt actcttcaag aaacacgcaa acgtgaattc tatgaaaaac
    12481 cttctgtaaa acgtaaacgt aaatcagaag tagctcgtaa acgtaaaaaa ttctaattga
    12541 aatgaaaggc tagagaaatc tagtcctttt tcttttaaat aaatactcca aagcctgcaa
    12601 aaatctgaaa cttcctccta caatttgata taatagagag aagaactcat ttgaaggagg
    12661 aaatgatgtc ggttttagta aaagaagtga ttgaaaagct tagactagac attgtctatg
    12721 gtgaaccaga gttgcttgaa aaggaaatca atacagcgga tattacgcga cctggtcttg
    12781 aaatgacagg ctattttgac tactatacac cagagcggat tcaacttttg gggatgaagg
    12841 agtggtctta tctgatcagc atgccttcca acagccgtta tgaagttttg aaaaaaatgt
    12901 ttctacctga gacaccagca gtcattgttg ctcgtggttt ggtggttcca gaggagatgt
    12961 taaaggctgc tagagaatgt aagattgcta ttttaaccag ccgtgcagct accagtcgtt
    13021 tatctggaga gttatctagc tatctggatt ctcgtttggc agaacgtacc agtgtgcacg
    13081 gtgtcttgat ggatatttat gggatgggcg tcttgattca gggagatagt ggaattggta
    13141 agagcgagac aggtcttgag cttgtcaaac gtggtcaccg tttggtagcc gatgaccgtg
    13201 tcgatatctt tgccaaggat gagattactc tctggggtga accagctgaa attttgaaac
    13261 acttgattga aattcgtggg gttggtatta tcgatgttat gagtctctac ggtgcgagtg
    13321 ctgtcaagga ttcttcacag gttcagcttg ctgtctattt ggaaaattac gatacacata
    13381 agacctttga tcgtcttgga aacaatgcag aggaacttga agtttctggc gtagccattc
    13441 ctcgtattcg tattccagtt aaaacaggtc gtaatatctc tgttgtgatt gaggcagctg
    13501 ccatgaatta tcgtgccaag gaaatgggct ttgatgcgac ccgtttgttc gacgaacgac
    13561 tgacaagtct cattgctcga aatgaggtgc aaaatgcttg atccaattgc tattcaacta
    13621 ggacccctag ccattcgttg gtatgcctta tgtattgtga caggcttgat tcttgcggtt
    13681 tatttgacca tgaaagaagc acctagaaag aagatcatac cagacgatat tttagatttt
    13741 atcttagtag cctttccctt ggctatttta ggagctcgtc tctactatgt tattttccga
    13801 tttgattact atagtcagaa tttaggagag atttttgcca tttggaatgg tggtttggcc
    13861 atttacggtg gtttgataac tggggctctt gtgctctata tctttgctga ccgtaaactc
    13921 atcaatactt gggattttct agatattgcg gcgcctagcg ttatgattgc tcaaagtttg
    13981 gggcgttggg gtaatttctt taaccaagaa gcttatggtg caacagtgga taatctggat
    14041 tatctacctg gctttatccg tgaccagatg tatattgagg ggagctaccg tcaaccgact
    14101 ttcctttatg agtctctatg gaatctgctt ggctttgcct tgattctgat ttttagacgg
    14161 aaatggaaga gtctcagacg aggtcatatc acggcctttt acttgatttg gtatggtttc
    14221 ggtcgtatgg tcatcgaagg tatgcgaaca gatagtctca tgttcttcgg ccttcgagtg
    14281 tcccaatggc tgtcagttgt ctttatcggt ctcggtataa tgatcgttat ttatcaaaat
    14341 cgaaagaagg ccccttacta tattacagag gaggaaaaat aaatgttaga agttgcatat
    14401 attcttgttg ccctagcttt gattgtcttt ttggtctatc tgatcattac tgtacaaaag
    14461 cttggtcgtg tcatcgatga aacagaaaag acgattaaaa ccttgacttc agatgtggat
    14521 gtgaccttgc atcacaccaa tgagttgttg gctaaggtca atgtcttggc agatgatatc
    14581 aatgtcaagg tggctacgat tgatccactc ttcagtgctg ttgcagattt atctctatct
    14641 gtttcagacc tcaatgacca tgcgcgtgtc ttgagcaaga aagcttcatc agctggttca
    14701 aaaacactca agactggtgc aagtctgtca gctcttcgtc ttgcaagtaa atttttcaaa
    14761 aaataaaaaa ggagaatcct tatgggtaaa ttatcctcaa tccttttagg aacggtttca
    14821 ggtgcagctc ttgccttgtt tttaacaagt gataagggca aacaagtttg cagtcaggct
    14881 caagattttc tagatgattt gagagaagat ccggagtatg ccaaggagca agtctgtgaa
    14941 aaactgacag aagttaagga gcaggctaca gattttgttc tgaaaacaaa agaacaggtt
    15001 gagtcaggtg aaatcactgt ggacagtata cttgctcaag ctaaatccta tgcttttcaa
    15061 gcgacagaag catcaaaaaa tcaattaaat aatctcaagg aacaatggca agaaaaagcc
    15121 gaagctcttg atgactcaga agagattgtg attgatataa cagaagaata aaccatcacc
    15181 atctccggac ggactatgta tctggggatg gtgattttta tctggaatct agtctttgtg
    15241 gtataataat tactatgcag aaaaaaccaa cgtcagccta tgtgcacatc ccattttgta
    15301 cccagatttg ttattattgt gatttttcaa aggtcttcat caaaaatcag ccagtcgaca
    15361 gctatttaga gcatctgctg gaagagtttc gttcttatga tattgaaaag ttgtcaaccc
    15421 tttatatcgg tggtggaaca ccgacagccc tgtcggctcc gcaactggag gtgttactga
    15481 atggcttgac taaaaacttg gacttgtctg tcttggaaga gttgaccatt gaagccaatc
    15541 caggcgattt ggatgcggat aagatagctg ttttgaaaaa ttcggctgtc aatcgtgttt
    15601 cgctaggtgt ccagaccttt gatgataaga tgttgaaaaa gattgggcgc agtcatttgg
    15661 agaaggatat ttatgaaaat atcgatcgtc tgaaactggc tggttttgac aacatctcca
    15721 ttgatttgat ttatgctctg cctggtcaga ccatggagca agtaaaggaa aatgtggcta
    15781 aagccattgg actggatatt ccccacatga gtttgtatag tttgatttta gaaaaccata
    15841 cggtctttat gaaccggatg cgacgtggga aattgcctct gcctaaggag gaactagaag
    15901 cggagatgtt tgagtacatc attgcagagc tggagcgagc gggttttgag cattatgaga
    15961 tttctaattt ctccaaaccc ggttttgaaa gtcgtcacaa tctcatgtac tgggacaatg
    16021 ctgaatacta tggtattggt gcaggggcat ctggttatgt caatggagta cgctataaaa
    16081 atcatggtcc cattcgtcat tatctcagtg cggttgagga aggcaatgct tgtattacag
    16141 aagatcacct gagtcaaaag gagcaaatgg aagaagaaat gttcttggga ctccgcaaga
    16201 aatccggggt ttccatggcg cgatttgagg aaaaatttgg acagtctttt gctggacttt
    16261 atggagaaat tgtcagagat ttggttcaac aaggcctcat gcagattgag ggtgaccacg
    16321 ttcgcatgac aaagagaggt ctctttttgg gagatactgt agcagaacga tttattttgg
    16381 agtaggatca tgggcttaac ttatcaaatg aaaatgaaaa ttccttttga tatggctgat
    16441 atgaacggtc atatcaaact tccagatgtg attttgctgt cactgcaagt ttcagggatg
    16501 cagtcgattg aactgggagt tagtgataag gccattttgg aagaatataa tctggtctgg
    16561 attatcgtag aatatgatat tgaggtggtt cgtttgcctc gttttgcgga agaaattacc
    16621 atcgaaacgg aagccttgag ctacaatcga cttttttgct accgtcgctt tactatttat
    16681 aatgaagcgg agcaggagct catccacatg atggcgacct ttgttctcat ggaccgcgac
    16741 agtcgaaaag tccatgttgt tgaacctgag attgtggctc cttaccagtc tgattttgat
    16801 aaaaaactta tccgtggacc gaagtatgag tccttggaag aaccgatcag caaggattac
    16861 catgttcgtt tttacgactt ggatatgaat ggtcatgtca ataacagtaa atacttggac
    16921 tggatttttg aggtcatggg agcggatttt ttgacccact atattcccaa gaaaatcaac
    16981 ctcaagtatg tcaaggaagt tcgaccaggt ggggtgatta catcggctgt tgaacggact
    17041 ggactggaaa gcaagcatga aattacaagt gatggggtta tcaatgccca agcaatcatt
    17101 acttggcaag aaataaaaaa ggcttaggga gaaatagatg aaatataaag gctatttaat
    17161 tgatttagac ggaaccattt ataaggggaa agaccgaatc cctgctggag agacttttgt
    17221 tcatgaattg caaaagcggg acattcccta tctctttgta accaacaata caacccgcac
    17281 tccagagagt gttaaggaga tgttggctca gaattttaat atcgatacgc ccctatcgac
    17341 tgtctacaca gcgactttgg caaccatcga ctatatgaat gatttggggc ttgaaaagac
    17401 cgtctatgtc gtcggagaag caggactcaa ggaagccatc aaggcggctg gttatgtgga
    17461 agacaaggaa aaacctgcct acgtggtagt tggtctggat tggcaagtcg actatgaaaa
    17521 atttgccaca gcaactcttg ctattcaaaa gggtgcccat tttatcggaa ccaatcctga
    17581 cctcaacatc ccgacggaac gcggtctttt gccaggtgct ggctcactga ttacgctgct
    17641 tgaagtagcg acacgagtga agccggttta tatcggaaaa ccaaatgcca tcattatgga
    17701 caaggcggtt gagcacttag gtttggaacg tgaagagtta atcatggttg gggacaatta
    17761 tttgactgat atccgggctg ggattgacaa tggcattcca acgctcttgg tgacgacagg
    17821 ttttaccaag gcagaagaag tagctggcct gccaatcgca ccgacacatg tggtttctag
    17881 ccttgcggag tgggattttg atgaaaacta aattgacctt ttggggctct atgctctttc
    17941 tcctctccct ctcaatcctt ctgaccattt atctggcttg gattttctat cctatggaga
    18001 ttcagtggct aaacttaacg aatcgagtct atctaaaacc agaaaccatt caatacaatt
    18061 ttcatatctt gatgaattat ctgaccaatc cttttagtca ggtcttacag atgcctgatt
    18121 ttcgttcgtc agcagctggt ctgcaccatt tcgcagtggt caagaatctc tttcatttgg
    18181 ttcagctagt agctctagtg acactgccaa gtttctatgt ctttgtcaat aggattgtga
    18241 aaaaggactt tttgtctctt tatcgaaaaa gtctcctggc tctagtagtc ttacctgtga
    18301 tgattggact tgggggagtt ttgattggtt ttgaccaatt ctttactctt ttccatcaaa
    18361 ttctctttgt gggagatgat acctggcttt ttgatccagc caaggatcct gttattatga
    18421 ttttgccaga gaccttcttt cttcatgcct tcctcctctt ttttgccctc tatgaaagct
    18481 tctttggcta tctgtgtctg aaaagtcgta ggaagtgaaa tgaaagatgt ttttaatttg
    18541 catatataaa aatatatatc gtttaaaacc atcgttaaga gtgaattaac caaatccaat
    18601 tgtgtcaatc gttcgcaaac agcctatttt tcttgaaaaa ataggctttt tttctaaaaa
    18661 tccctagtca agcgccttat ttttttgtat aatagaagta gcaaagtata gataagaaga
    18721 gaaaagcatg attacactat ttctatcacc gagctgtaca tcatgtcgta aggctaaggc
    18781 ctggttagaa aaacataagg ttccctttgt ggaacacaat attatgacca gtcctttaac
    18841 aagaaaagaa ttgcaacaca tcctttcctt gaccgaaaat ggtactgatg acatcatttc
    18901 aactcgttca aaaatttttc aaaaattgaa tattgatgta gagagtattt cggtatcgga
    18961 attgcttcat ttgattgagc agtatcctag tcttttgcgt cgtccaatta ttattgatgc
    19021 caagcgtatg caaatcggtt ttaatgaaga tgagattcgt gcttttctcc ctcgtagtta
    19081 tcgtaagcaa gaactaaaag aagcaagaat gagagctggt attagttaat gaacaaacag
    19141 tatagttacc cactagattt gtcgtggagc actgaagaac ttgcttcagt gctttctttt
    19201 tttaatgatg ttgaagctgc ctatgaaggc aaagtagagg ctaaaaagtt actggactcc
    19261 tataagggat tcaaagcggt cgtgccaagc aagagcgaag agaaacgttt gggacgagaa
    19321 tttgaaacgg ttagtggcta ttcactttac cgagcagttc aggctgccaa agaaaaaggg
    19381 gaaggaaaga tttctcttgg aaagtaaatt tgaatttgct aaagagcttg ttaagaaagc
    19441 aggtcagtac attcttgacc atatgcagga agacttgcgt gttgaaacca agtcctctcc
    19501 aacagatttg gtgaccagac tggacaaaga agttcaggaa ctcttggttg gtgagatttt
    19561 gtcccgttat cctgaggata agatttgtgc tgaagaaggt tgtctgcgag cctcggttca
    19621 agagggcaag gtttgggtca ttgatcccat tgatggtacc aataattttg tagcccagca
    19681 ggaagatttt gctgttatga tggcttattt tgaaaatggt cagggacagt ttggtctgat
    19741 ttatgatgtg gtcaaagggg attgttacca cggtggtggg gaatttccag tttgtctaaa
    19801 tgataggccc ctagctcctt ttaaaactaa accacttgga gattttctca ttgcagggaa
    19861 tagtggtatg ctggaaacca atgaatgggg gctggctgat ttgagccgag cggttcttgg
    19921 tgttcgtgtc tatggaagtg cggccattag ttttgccaag attttgtcag ggcgtttgtt
    19981 gacctatctc acttatctgc aaccatggga ttatgccgca gctagtattt taggggaaag
    20041 tctgggctat cgggttgtga ccctttttgg tgaagctcct gattttcaaa ccagacagcc
    20101 ggtcatgatg gtgcctcttg agatgcagga ggaaattcag tcctatattt acgaaaggaa
    20161 aagaacttaa atgcaatttc cagaaggatt tgttgaaaaa tataaagaga tactaggaga
    20221 tgaggcaaga gattttcttg cctcttttga ggaggaagcg gtttcggcct ttcgggtcaa
    20281 tcccttaaaa gaagagcaac tttccttttc tgatgccatt actcaaaccc cttggggcca
    20341 ctatgggaag gtttcaggga aatcgcctga gcatgctaca ggtttagttt attcgcaaga
    20401 acctgctgct caaatggtgg ctcaagtagc tcaacccagt cctggtatga aggtcttgga
    20461 cttggctgct gcaccggggg gcaaatcaac tcaactggca gcctatctag caggggaggg
    20521 gctacttgtt tccaatgaaa tttcaagcaa acgggctaag attttggttg aaaacatgga
    20581 gcgttttgga gcgacaaatg tcgtggtgac caatgaatct gccgaccgct tggtcaaggt
    20641 ctttaaaggc tattttgact taatcgttct tgatgcccct tgctctggtg aaggaatgtt
    20701 tcgtaagcaa cctgatgcta tggactattg gagcttagat tatccgagtc aatgtgctag
    20761 cttgcaaaga gaaattctgg aggatgcagt gaccatgtta gctgaaggtg gtcgtctggt
    20821 ttattcgacc tgtacctggg cacccgagga aaacgaagag attgtcaatt ggttgctgga
    20881 agagtatgat tttgacttgt tgccagtaga gcatatcaat ggaatggtag ctggtattga
    20941 cctgccagaa acggctcgga tgtaccctca tcagtttaag ggagagggtc agtttgttgc
    21001 ccatctacag tttaagggta acaatccagc tcctaaattt aaggcaagta agagtaacct
    21061 cagccgtgaa caagttgcct tgtggcagga atttgcccaa aaccatttga aggtcaatct
    21121 accgggtatc ttgcagactt ttggagacca gctttatctc ttgccagaac ttttgccaga
    21181 tttagggaag ctcaagattg ctcgcaatgg actgcatctg ggtactttta agaagaaacg
    21241 ctttgagccc agtttcgctc ttggtttagc cttgaaatcg agtcaggtcg aacagtcggt
    21301 tgaaattggc caagaagcgt ttgtcaagta tgcggctgga gaaatcgttc agctggcaga
    21361 aagtctgcca aatggttggt accaagtttt ggttaaaggc aatggcttgg gctttgcaaa
    21421 ggttactgga aatgttttga aaaattattt tccaaaaggc ctcagattca aatgaaaatg
    21481 ctagtcaaat atcttattct atgttatagt gaaagtatgg atttttttag taggatgatt
    21541 cttgatatct tgattgccat tacatgtagt tttactactc aatgaaaatc aaagagcaaa
    21601 ctaggaagct agccatagat agctcaaaac actggtttga agagattttc aaagagtaca
    21661 agaagtttag ttattagcgt tcttaccgct tgtaaactag atttctcata aaatagaatc
    21721 ttttcctttt agttgtaaac tagtctggga gagtagagag gtttgagata cctttctagc
    21781 ttttggatta tcatctaagg agagtaattt cccttgcatt aaaaagggga aaaagagaca
    21841 cgaaatgact ataatgggtg acaatggggg aagggataga caagagattt tatccacata
    21901 tgaaaaaagg aggttaggag agagtaatat agcctatatt atataaataa tcaattgcgc
    21961 agaaatttgg taagaattca tgcgtcaact cataaagaac tacttaaaaa attcacagta
    22021 ttcataatta ttttcgagga gaaaaacagt gaaaaaaaga aaaaagcttg ctctgtctct
    22081 tatcgctttt tggctgacgg cttgtttagt aggctgtgct agctggattg atcgtggaga
    22141 atccataacg gctgttggct caactgcctt gcaacccttg gttgaagtag cggcagatga
    22201 atttggcacg atccatgttg gaaaaacggt caatgtccaa gggggaggtt ctggtacagg
    22261 cttgtcccag gttcagtctg gggcagttga tataggaaac tcagatgtat ttgctgagga
    22321 aaaagacgga attgatgctt ctgctcttgt tgaccacaag gtcgcggtag ctggcttggc
    22381 tctgattgtc aataaggagg ttgatgttga taacctaacg acagagcaac ttcgtcaaat
    22441 cttcataggt gaggtaacca attggaaaga gtttggtggt aaggacttac ccatctctgt
    22501 tatcaatcgg gcagccggct ctggttctcg tgctaccttt gatactgtca ttatggaagg
    22561 tcagtctgcc atgcaaagtc aggagcagga ttcaaatgga gcggtaaaat caatcgtatc
    22621 aaaaagtcca ggagctatct cttatttatc tcttacctat atagatgatt cggtcaaaag
    22681 catgaagttg aatggctatg acttaagtcc agaaaatata agtagcaata attggccctt
    22741 gtggtcttat gagcatatgt atacattggg gcagcccaat gagttggctg cagaatttct
    22801 caattttgtt ctctcggatg agacccaaga agggattgtc aaaggattga agtatattcc
    22861 gattaaggaa atgaaggttg aaaaagatgc tgccggaact gtgacagtgt tggaagggag
    22921 acaataatga atcaagaaga attagctaag aaaatgttgc ttccatcaaa gaattctcgt
    22981 ctggagaaat taggaaaagg tttgaccttt gcctgtcttt ctttgatagt catccttgtg
    23041 gccatgattt tggttttcgt agcgcaaaaa ggcttgtcga ccttctttgt caatggtgtg
    23101 aatatctttg actttctttt gggaggaact tggaatcctt ctagtaaaga atttggtgcc
    23161 cttcctatga ttttgggttc ctttatcgtt accattctct cagcccttat cgcaacaccc
    23221 tttgctattg gtgcagcagt ttttatgacc gaagtatcac caaaaggggc gaagattttg
    23281 caaccagcta ttgaactcct ggttgggatt ccttcagtag tgtacggatt tattggcttg
    23341 caagtcgtcg ttccctttgt tcgcagtgtc tttggtggga ctggttttgg gattttgtca
    23401 gggatttccg tcctctttgt catgattttg ccgaccgtaa cctttatgac aacggatagc
    23461 ttgcgtgcgg ttcctcgtta ttatcgtgag gccagtttcg ctatgggagc cactcgctgg
    23521 cagactatct ggcgtgtgat cttgaaggcg gcccgttctg gtattttcac tgcagtggtc
    23581 tttgggatgg cgcgtgcctt tggtgaggct ttagctatcc agatggttgt cggaaactca
    23641 gctgttatcc caacttcctt gaccacacca gctgcaactt taacttctat attaactatg
    23701 ggaattggga acactgtcat gggaactgta aataataatg ttctctggtc actggccttg
    23761 gtactgctct tgatgagttt agtttttaac agtgtgatta aattgattac gaaagaaaga
    23821 ggaaagaaaa attatgcgcg ctaagaaatt agataaactt gcaacagctg tcctctatac
    23881 gattgctagc atcattgtga caatcttggc ttccttaatt ctctatatct tggttcgggg
    23941 cttgccccat atctcttggt ctttcttgac tggaaggtct tctgcttttc aagcaggtgg
    24001 tgggattggc attcagcttt acaattcctt tttcctattg gtcattacct tgattatttc
    24061 tgtacctctt tctatgggag ctgggattta cttggctgaa tatgctaaaa aaggtcctgt
    24121 taccaacttt gtgcggactt gtattgaaat cttgtcctct ttaccatcag tggtggtggg
    24181 tctctttggt tacttgatct ttgtagtcca gtttgagtat gggttttcaa tcatttcagg
    24241 tgccttggcc ttgacagtct ttaacttgcc tcagatgacg cgtaatgtag aggatagttt
    24301 gaaacacgtt caccataccc aacgtgaggc tggtctggct cttgggattt ctcgctggga
    24361 gacagtggtt catgttgtta ttccagaagc gcttccaggt attgtaacgg gtgtcgtctt
    24421 ggcatctggt cgtatctttg gcgaagctgc agctctgatc tatacagcag ggcaatcggc
    24481 gccagctctt gactggtcta actggaatat cctcagtgtg actagcccca tctctatctt
    24541 ccgtcaagca gaaaccttgg ctgtccatat ctggaaagtc aatagtgaag gcactattcc
    24601 agatggaacc attgtatcag caggttctgc cgctgtgctc ctgatcttta tcctgatttt
    24661 taactttgga gctcgtaagt tcggaagcta tctacacaag aaattaaccg ctgcctaaag
    24721 gagaagccat gtcaacatat aactgggatg agaagcatat ccttaccttt cctgaagaaa
    24781 aagtagccct ttctactaag gatgtccatg tttactatgg taaaaatgaa tccattaagg
    24841 ggattgatat gcaatttgaa agaaataaaa ttacagcttt gattggtccg tcgggatcgg
    24901 ggaaatctac ctacttacgc agtctcaatc gcatgaatga taccattgat attgctaaag
    24961 taactgggca gattctctat cgtggaattg atgtcaaccg tccagaaatc aacgtttatg
    25021 aaatgcgtaa acacattgga atggtttttc aacgccccaa tccatttgct aagtcaattt
    25081 accgtaatat tacctttgcg catgaacgtg ctggagttaa ggataagcaa gtcctagatg
    25141 aaatcgtaga aacctccctt cgtcaggctg ccctctggga tcaggttaaa gacgatctcc
    25201 acaagtcagc cttgacctta tcaggtggtc agcaacaacg tctctgtatc gctcgtgcca
    25261 tctctgttaa gccagatatc ctcttaatgg atgagccagc ctcagccttg gatccgattg
    25321 cgaccatgca actagaagag accatgtttg agctcaagaa aaactttacc atcatcattg
    25381 taacgcataa tatgcagcag gctgctcgtg caagtgacta tacaggcttc ttttacttgg
    25441 gtgatttgat tgagtatgac aagactgcaa ctattttcca aaatgccaag ctacagtcca
    25501 ccaatgacta tgtatctggt cactttggtt agaaaggaaa ccgtatgaca gatgcgattt
    25561 tacaggtatc agacctgtcc gtttattata ataaaaagaa ggctttgaat agtgtttccc
    25621 tatctttcca acctaaggaa attacagcct tgattggtcc atctggatca gggaagtcaa
    25681 ccctcctcaa gtctctcaac cgcatgggag atctcaatcc agaggtgacc acaactggat
    25741 ccgtggtgta caatggccac aacatctaca gtccgcgtac agatacggtt gaattacgta
    25801 aggaaatcgg aatggttttc caacaaccta atcctttccc tatgactatc tatgagaatg
    25861 ttgtctacgg gcttcgtatc aatggaatta aggataagca ggttctggat gaagccgtag
    25921 aaaaagcctt gcaaggtgcc tctatctggg atgaggtcaa ggatcgtcta tatgattcag
    25981 ctattggatt gtcaggtggt caacagcagc gtgtctgcgt ggcccgtgtc ttggcaacta
    26041 gtcctaaaat catcctcttg gatgagccaa cttcggcttt ggatccgatt tcagctggta
    26101 aaattgagga aaccttgtat ggtctaaaag acaagtacac catgcttctg gtaacccgtt
    26161 ccatgcagca agcttcacgt atctctgata agacaggatt tttcctagat ggagatttga
    26221 ttgaatttaa tgataccaag cagatgttcc ttgatcccca acacaaggaa acggaagact
    26281 atattacagg aaaatttgga taaggagatg aaagatgtta cgatctcaat ttgaagaaga
    26341 tttagagaaa ttacataacc agttctacgc tatgggacaa gaagtgctct cacaaatcaa
    26401 tcgtacggta cgtgcttttg tcacgcatga ccgtgacctg gcaaaagagg tcatcgaaga
    26461 tgatgcagaa gtaaatgaat acgaagtgaa actggaaaag aaatcatttg aaatgatcgc
    26521 actccaacaa ccagtctctc aagatttgcg tacagtcttg actgtcctta aggctgtatc
    26581 agatgtggag cgtatggggg atcacgctgt agccattgcc caggcaacca tccgtatgaa
    26641 gggggaagag cgcattccag ctgtagagga agaaattaaa aaaatgggac gtgaagttaa
    26701 aagcgttgtt gaagcagcac ttgatcttta tcttaatggt tctgttgacg acgcataccg
    26761 ggtggcctcc atggatgagc aaattaacca ctattttgaa actatccgtg accttgcgac
    26821 tgaagagatt aagaaaaatc cagaagccat tgttacgggt cgtgattatt tccaagttat
    26881 ttcctacttg gagcgtatcg gtgactatgc taaaaatatc tgtgaatggg ttgtctactt
    26941 tgaaacaggt aagattgtcg aactataaaa tagtttaatt ctgtataaaa aggagcttga
    27001 aatcaactga tggctccttt ttttgaacga aaaaatattt ttgagataaa aatttaaaaa
    27061 acacttgaca agtaacttgg atatcgttat aattatacaa aattaacaga gaggttgttt
    27121 atttatgaaa tcaaaaaaat ggatatttgt tttatgtaat tttcttgcaa gtttcttctt
    27181 agtagcttgt cagtcaggtt ctaatggttc tcagtctgct gtggatgcta tcaaacaaaa
    27241 agggaaatta gttgtggcaa ccagtcctga ctatgcaccc tttgaatttc aatcattggt
    27301 tgatggaaag aaccaggtag tcggtgcaga catcgacatg gctcaggcta tcgctgatga
    27361 acttggggtt aagttggaaa tctcaagcat gagttttgac aatgttttga ccagtcttca
    27421 aactggtaag gctgacctag cagttgcagg aattagtgct actgacgaga gaaaagaagt
    27481 ctttgatttt tcaatcccat actatgaaaa caagattagt ttcttggttc gtaaggctga
    27541 tgtggaaaaa tacaaggatt taactagcct agaaagtgct aatattgcag cccaaaaagg
    27601 gactgttcca gaatcaatgg tcaaggaaca attgccaaaa gctcaattaa cttccctaac
    27661 taatatgggt gaagcagtca atgaattgca ggttggaaaa gtagatgctg ttcatatgga
    27721 tgagcctgtt gcacttagtt atgctgctaa aaacgctggc ttagctgtcg caactgtcag
    27781 cttgaagatg aaggacggcg acgccaatgc cgttgctctt agaaaaaata gtgatgattt
    27841 gaaagaagtg gtagacaagg ttatccaaaa acttaaggat gaaggaactt accaaagcta
    27901 tcttgaaaaa gcagcaagtc taactgaagt tgaagaataa gaaaaagcag agttggatgt
    27961 cattccaatt ctgcttttaa atagtttaaa acattttcca gattgtctag ggacaccttg
    28021 gcaaattgat aaggacaggt gcttaaatag gcctcttcaa agaagtccaa gcccagttga
    28081 ctgtgtttga gactggcgat tttaggatac tgtctcaggt ctagcaataa accatcgtgt
    28141 aggggataat gaggaagggg acaaggtgtt ttagttatcc tttcctcgat ttgcttttgg
    28201 taagattcat gattggtcaa gcgagccaaa cgattttttt caaacaattg actgtcaata
    28261 tagagtgaca gggccttttg cataatgagg ttgctgtcgt agtctaggat atttttgtag
    28321 gccacaaatg cttctttgat agcatttgga agaatgagtg ctgtaatacg aagggcagga
    28381 aaaaggctgg tcgagaagga cttgatataa atgacatgct cctctgtatc aagatagtgg
    28441 aaggtttggc ccttcttgga gtccaaatca cccagataat cgtcctctac gatatagaca
    28501 tcatacttgg cagctaagtt aagaatagat cgtttgtctt gctcagaata ggaatgtccc
    28561 agaggatagt gaaatctagg aatggtgtag aaaaatttaa tttttcctgt tttgaagtgg
    28621 ccttccagct cctccaagtc aatcccatca atgcctcgtt caatcgtttg atagtccagc
    28681 ccctgtgcaa tcaagaggcg attcatccga tggtaggttg gctgttccac caagatttcc
    28741 ttggcttggc taggaaagga tatttgagag aggataaaca aggcttgttg ggttccagaa
    28801 gtcagtacta gttggttagc cttgcagtag agagcttgct caaataggag tttgtgaatg
    28861 gactgtctta ggtcttctaa tccttcttga ttgtcatagt agttgaagag gtagttttct
    28921 cgtccaatca aggtttcatt gacacagagt cggaaatcgt cataggcact ggcatgttcg
    28981 tcggtaacct cgatttctag gtcttgatgt tgcccttgtt ctaatacata gtagccactc
    29041 tgaggcttgg catagaggta ttgttcgtgc cgtaattcca gcagggctcg ttgaatggtg
    29101 tccttgctgc agtgaaagtc aaggctcagt tgacggatag aaggcaggcg actacccgtc
    29161 ggaaatcgtt cagactcgat accatttttc agataggaaa cgacctcttt gtacttgctt
    29221 tgtttcttca ttccagacct cccttgattt tgttacattg tacccttttt tttccttctt
    29281 ggcaatgtct agagcgtttc tctcgttcac atctaggggc aaatgtggta tacttaggag
    29341 taagatttat agaataacag acaagaaagt gaatggataa gaacgtgcag gaaccagtga
    29401 aattatttca atacaatact cttggagcct tgatggctgg cctttatggt ggtactatga
    29461 cagtaggaga attgctagaa catggtgacc ttggtttggg aaccttggat tccattgatg
    29521 gggaattgat tgtcttggat ggcaaggctt atcaggccaa agggtcagga gaccagccag
    29581 aaattgtgga agtgtcacca gatgccctta ttccttacgc tgcagtggta ccgcatcagg
    29641 cagaggtcat tttccgccag cgctttgaga tgacagacaa ggaattgaaa gaacgaattg
    29701 agtcttatta tgatggggaa aatcttttcc gctctatcaa gattcggggg gaatttttac
    29761 atatgcatgt gcgtatgatt cctaagtcaa cacccgatac caagtttgct gatgtcgcaa
    29821 cccatcaacc ggaatatagt cgtgacaatg ttgcggggac tattgttggt ttctggacgc
    29881 ctgagatttt ccatggggtc agtgtggcag gctaccatct gcacttcata tcagatgatt
    29941 tgaccttcgg tggacatgtc atggattttg tcatcaagga aggcattatc gaggtgggag
    30001 cagttgacca gttggaccaa cgtttcccag tccaagaccg tcaatacttg tttgctaagt
    30061 tcaatgttga cgagatgaaa aaagatattg aaaaggcaga ataggagaag aaaatgacca
    30121 ttcatatcat tattaccatg ttgctgttgc tagcttttct gataggaagc atttggtttg
    30181 ccaaaaagaa ataccagatt aatctagctg tcttgggctt gggtgcagtc gctttctttg
    30241 tctcttcgca gattttggaa aaactggtgc atatcttgat tttgcaccct caaaaagacg
    30301 gtagtattgc cctcttgcaa gatcatccgc ttatctatat tatctatggc ctagccatgg
    30361 cagcattttt tgaggaaacg gctcgtcttg ttttcttcaa atggttggag aaaaagagaa
    30421 gtttggaaaa ggcagatgcc ttggcctatg gcctagggca tggtggcttg gagttgattt
    30481 ttctaggcct tactagttta ctcaatcttt acatcgttct ttcggcagtt caaactcaga
    30541 atccacaggt tatgcaatta ctgtctgaaa atatgttaaa aaccattcag tcactttcgg
    30601 tctggcagat ttatttgctt ggttttgagc gaatcttggc gcttggtttc caattacttt
    30661 tgacagtttg ggtttaccaa gctgttcgcc agaagaaatg gatttatctc ctagcagcct
    30721 atggcttgca tgccttcttt gatctgtcac catctctttt ccaagtaggc tggttgacaa
    30781 atccagtctt ggttgaagtg attctagcac tggagctcgt tctggtcgcc tatggaacca
    30841 aggaaatctt ttgtaaaaaa tcataaaaag gggggaacct ctttttctta tgcaaaatcc
    30901 aaacaaggta tttttatggt cgtcaaatgt ctctaaaaat ggtataatgg aatgaatttt
    30961 gtaaaaggaa gagtgacatg tctgtaagag aaaaaatgct tgaaatctta gaaggaattg
    31021 atatccgttt taaggaaccc ttgcatagct atagttatac aaaagtaggt ggagaggctg
    31081 attatttggt ctttccacga aatcgttttg agttggctcg cgttgtgaaa tttgccaacc
    31141 aagaaaatat cccttggatg gttcttggca atgcaagcaa tatcatcgtt cgtgatggtg
    31201 ggattcgtgg atttgtcatc ttgtgtgaca agctcaataa cgtttctgtt gatggctata
    31261 ccattgaagc agaagctggg gctaacttga ttgaaacaac tcgcattgcc ctccgtcata
    31321 gtttaactgg ctttgagttt gcttgtggta ttccaggaag cgttggcggt gctgtcttta
    31381 tgaatgcggg tgcctatggt ggcgagattg ctcacatctt gcagtcttgt aaggtcttga
    31441 ccaaggatgg agaaatcgaa accctgtctg ctaaagactt ggcttttggt taccgccatt
    31501 cagctattca ggagtctggt gcagttgtct tgtcagttaa atttgcccta gctccaggaa
    31561 cccatcaggt tatcaagcag gaaatggacc gcttgacgca cctacgtgaa ctcaagcaac
    31621 ctttggaata cccatcttgt ggctcggtct ttaagcgtcc agtcgggcat tttgcaggtc
    31681 agttaatttc agaagctggc ttgaaaggct atcgtatcgg tggcgtagaa gtgtcagaaa
    31741 agcatgcagg atttatgatc aatgtcgcag atggaacggc caaagactac gaggacttga
    31801 tccaatcggt tatcgaaaaa gtcaaggaac actcaggtat tacgcttgaa agagaagtcc
    31861 ggatcttggg tgaaagccta tcggtagcga agatgtatgc aggtggtttt actccctgca
    31921 agaggtagtg gggacctgac agagccccga tcggttaatc tatgaaaaag aaggaattta
    31981 tgccaattga aaaaaccaat tatcgaattc aaaaacgtct ctaaagtttt tgaagacagc
    32041 aacaccaagg ttctcaaaga catcaacttt gagttggaag aagggaaatt ctacaccctt
    32101 ctaggtgcat ctggttcggg gaaatcaact atcctaaaca ttattgcagg tttactggat
    32161 gcgacgacag gagatatcat gctagacggt gttcgtatca atgatattcc aaccaacaag
    32221 cgcgacgtac ataccgtctt ccaatcctat gccttgttcc cacatatgaa tgtgtttgaa
    32281 aatgttgcct ttccacttcg cttgcgtaaa attgataaga aagaaatcga gcagcgtgta
    32341 gcggaagttc tcaagatggt tcagttggaa ggttatgaaa aacgttccat ccgcaaactt
    32401 tctggaggac aacgtcagcg tgtggccatc gcccgtgcta tcatcaacca accccgtgtg
    32461 gtcttgttgg acgagccttt atcagcgctg gacttgaaat tgagaacaga catgcagtac
    32521 gaattgcgtg aattacaaca acgattgggc attacctttg tctttgtcac tcacgatcag
    32581 gaagaagctc ttgccatgag tgactggatt ttcgttatga atgatggcga gattgtccag
    32641 tctggaaccc ctgtggacat ctacgatgag ccaatcaacc actttgttgc cacctttatc
    32701 ggggagtcaa acatcttgcc aggtaccatg attgaggact acttggtcga atttaacggc
    32761 aaacgctttg aagcggttga tggtgggatg aagccaaatg aacctgttga ggtcgttatt
    32821 cgtccagagg acttgcgcat tacccttcct gaagaaggca agctccaagt taaggtcgat
    32881 acccagcttt tccgtggagt tcattatgaa attatcgcct atgacgaact tggaaatgaa
    32941 tggatgatcc actcaacccg taaggctatc gtgggtgagg aaatcggtct ggactttgaa
    33001 ccagaagaca tccacatcat gcgtctcaat gaaaccgaag aagagttcga tgctcgtatt
    33061 gaggagtacg tagaaatcga agagcaagaa gcaggtttga tcaatgcaat cgaggaggaa
    33121 agagatgaag aaaacaagct ctaaactctt tgtagtaccc tacatgcttt ggattgcgct
    33181 ctttgtattg gcacccttgg tcttgatttt cggtcaatcc tttttcaaca tcgaaggcca
    33241 gttcagttta gaaaattaca aatcttactt tgcgtcacaa aacttgacct atcttaaaat
    33301 gagtttcaac tcagtgcttt atgcaggcat tgtgaccttt gtggcactgc ttatcagtta
    33361 tccgacggcc ctctttttga cccgtctcaa acaccgtcaa ctctggctca tgctgattat
    33421 ccttcctacc tggatcaatt tgctccttaa agcctatgct tttatcggga tttttggtca
    33481 aaatggctct attaaccaat tcttggaatt tatcggaatt ggttcacaac agttgctttt
    33541 taccgatttt tcctttatct ttgtcgcaag ctacatcgag ctccccttta tgattttgcc
    33601 gattttcaat gtcttagacg atatggataa taatctcatc aatgctagtt atgaccttgg
    33661 tgcaactaag tgggagacct tccgtcatgt catcttccct ctatctatga acggtgtgcg
    33721 aagtggggtt cagtcggtct ttatcccaag tttgagtctc ttcatgctga cccgtttgat
    33781 tggtgggaac cgcgttatca ccttggggac ggctattgag cagaattttc taaccaatga
    33841 caactatggt atgggttcaa ccatcggtgt gattctcatc ctgaccatgt tcatcaccat
    33901 gtgggtgacc aaggaaagga gagaacgatg aaaaaatttg ccaaccttta tctgggactg
    33961 gtctttctgg tcctctacct gccgattttt tacttgattg gctatgcctt taatgctggt
    34021 gatgatatga atagctttac aggttttagc tggactcact ttgaaaccat gtttggagat
    34081 gggagactca tgctgatttt gactcagacc tttttcttgg ccttcctatc agccttgata
    34141 gcgaccatta tcgggacttt tggtgccatt tacatctacc agtctcgtaa gaaataccaa
    34201 gaagcctttc tatcactcaa taatatcctc atggttgcgc ctgacgttat gattggtgct
    34261 agcttcttga ttctctttac ccaactcaag ttttcacttg gctttttgac cgttctatct
    34321 agtcacgtgg ccttctccat tcctatcgtg gtcttgatgg tcttgcctcg actcaaggaa
    34381 atgaatggcg acatgattca tgcggcctat gacttgggag ctagtcaatt tcagatgttc
    34441 aaggaaatca tgcttcctta cctgactccg tctatcatta ctggttattt catggccttc
    34501 acctattcgt tagatgactt tgccgtgacc ttctttgtaa caggaaatgg cttttcaacc
    34561 ctatcagtcg agatttactc tcgtgctcgc aaggggattt ccttagaaat caatgccctg
    34621 tctgctctag tctttctctt tagtattatc ctagttgtag gttattactt tatctctcgt
    34681 gagaaggagg agcaagcatg aaaaaaatct attcattttt agcaggaatt gcagcgatta
    34741 tccttgtctt gtggggaatt gcgactcatt tagatagtaa aatcaatagt cgagatagtc
    34801 aaaaattggt tatctataac tggggagact atatcgatcc tgaactcttg actcagttta
    34861 cagaagaaac aggaattcaa gttcagtacg agacttttga ctccaacgaa gccatgtaca
    34921 ctaagataaa gcagggtgga acgacctacg atattgccat tccaagtgaa tacatgatta
    34981 acaagatgaa ggacgaagac ctcttggttc cgcttgatta ttcaaaaatt gaaggaatcg
    35041 aaaatatcgg accagagttt ctcaaccagt cctttgaccc aggtaataaa ttctccatcc
    35101 cttacttctg gggaacctta ggaattgtct acaacgaaac catggtagat gaagcgcctg
    35161 agcattggga tgacctttgg aagccggagt ataagaattc tatcatgctc tttgatgggg
    35221 cgcgtgaggt gctgggacta ggactcaatt ccctcggcta cagcctcaac tccaaggatc
    35281 tgcagcagtt ggaagagaca gtggataagc tctacaaact gactccaaat atcaaggcta
    35341 tcgttgcgga cgagatgaag ggctatatga ttcagaataa tgttgcaatc ggcgtgacct
    35401 tctctggtga agccagccaa atgttagaaa aaaatgaaaa tctacgttat gtggtaccga
    35461 cagaggccag caatctttgg tttgacaata tggtcattcc caaaacagtt aaaaaccaaa
    35521 actcagccta tgcctttatc aactttatgt tgaaacctga aaatgctctc caaaatgcgg
    35581 agtatgtcgg ctattcaaca ccaaacctac cagcgaagga attgctccca gaggaaacaa
    35641 aggaagataa ggccttctat cccgatgttg aaaccatgaa acacctagaa gtttatgaga
    35701 aatttgacca taaatggaca gggaaatata gcgacctctt cctacagttt aaaatgtatc
    35761 ggaagtagga gataaacgta agaagacgaa tcagtcaagc tggttcgttt ttaaggaata
    35821 gaagtcagtt tttagagccc tatctttttc tattctagtt gtttatttgt ttatttgctt
    35881 atttgcttgc ctagtagtat actaagccta tactcttcaa accacgtcag cgttgccttg
    35941 ccgtactcaa gtacagcttg aggctagctt cctagtttgc tttttgattt ttattgagta
    36001 ttaaccttac agaaagcggc aacaaataat gaaaatgtct acttttttca aaaaaagttt
    36061 ctggccaacc tttatgattg ttaaccaaac tgttatacta ttccatttaa aggatggctt
    36121 ggatcgacaa tacctaacaa ctgagtccat atattgggtg ataggcacct ttatatttgg
    36181 aaatattcta gtagctgtgt ttagtaatat gaaaatttgg gataaaaaga aaaacggcag
    36241 taagaaaaaa tatatcctga aaaagtaatc agagatgtag ggaattggtc taattcaacg
    36301 gagatcattt ccagttgacg caagcttaaa aaaacgttat aataagaaag ttgagaattg
    36361 attttcactt gtcttagtcc agagaaatgg cggtgctgcg agccatctaa gctaggaagt
    36421 catgctactc aatcatacaa ttgcataaga acaagagaat gacaagttca ttgaatgaag
    36481 gtggtaccgc ggtttttcgc ccttcgtgat atgagcttgt cttttgattt ttggaggtgt
    36541 tgatgaaaac atttcttgtc aaacaaaagt ttcgtcttgg aggcgaacgc ttcgctatca
    36601 agaatgacag gggagaaatt gcctatcagg tggagggatc attttttaag attcctaaaa
    36661 cctttaccat ctatgatgcg gctggtgaac aagtcagtga gattagtaaa gaaatcttga
    36721 ccttgcttcc tcgttttgag attcagcttc gggatggctc gagttttgtc attcgtaaga
    36781 agttgacctt ctggcgagat aagtatgagt ttgataatct aggtcttcgt atcgagggca
    36841 atatctggga tttgaatttc aaattgctgg atgatcgcga tcagctgatt gcggaaatta
    36901 agaaggaact cttccatctg acctctacct ataccgtaac ggttcttgag gacgcttatg
    36961 cagacctagt catttccctc tgtgtcgcga ttgactatgt ggaaatgctg gaaagccaat
    37021 cacattaaac aagtaaataa ggagacaata tgaaacaact atctagtgca caagtacgcc
    37081 aaatgtggct tgatttctgg gcgaccaaag ctcactcagt agaaccatca gtaagtttgg
    37141 ttcctgtaaa tgacccaact cttttgtgga tcaactctgg ggtagcaacc cttaagaaat
    37201 actttgacgg gaccattatc cctgaaaatc cacgtattac caatgcccaa aaggctatcc
    37261 gtaccaacga catcgaaaac gtagggaaga ctgcgcgtca ccataccatg tttgaaatgc
    37321 tggggaactt ctctatcggg gattacttcc gtgacgaagc tatcacttgg gcttatgagc
    37381 ttttgacaag ccctgaatgg tttgatttcc ctgctgaaaa actttacatg acctactatc
    37441 cagacgataa agattcttac aaccgctgga ttgaagtggg agtggatcca agtcacttga
    37501 ttccaattga ggacaacttc tgggaaatcg gtgcgggacc ttctggacca gatacagaaa
    37561 tcttctttga ccgtggggaa gcctttgacc cagaaaatat cggtcttcgc ctgcttgcag
    37621 aagatattga aaacgaccgt tatattgaaa tctggaacat cgttttgtca caatttaacg
    37681 cagaccctgc tgttcctcgt agcgaataca aggaattgcc acataagaac attgatacgg
    37741 gcgctggttt ggagcgtttg gtggctgtta tccaaggggc taagaccaac tttgaaacgg
    37801 acctcttcat gccgattatc cgtgaagtcg agaaattgtc tggtaaggtt tatgaccaag
    37861 atggcgacaa catgagcttc aaggttatcg cagaccacat tcgttctctt tcatttgcta
    37921 tcggtgatgg tgcccttcca ggaaatgaag gtcgtggtta tgttcttcgt cgtcttctcc
    37981 gtcgtgcttc tatgcatggt caaaaattgg gtatcaacga acctttcctt tacaaattgg
    38041 ttccaactgt tggaaaaatc atggaaagct actacccaga agtgcttgag aaacgtgact
    38101 ttattgagaa aatcgttaag agcgaagaag aatcatttgc ccgtaccctt cactcaggtc
    38161 aacactttgc ccaaggcatt gtagcagact tgaaagaaaa aggtcaatct gttatcgctg
    38221 gttcagatgt cttcaaactc tatgatactt atgggttccc agttgaattg actgaagaaa
    38281 tcgctgaaga agctggtatg actgtagacc gtgaaggttt tgaagcagcc atgaaagaac
    38341 agcaagaacg cgcgcgtgcc tcagctgtca agggtggctc aatgggtatg caaaatgaaa
    38401 ctcttcaaaa catcactgta gaaagtgtct tcaactacaa tgctagccaa ttgtcttcta
    38461 aattggtagc tatcgtggcg gacaatgcag aagtagaagc tgtttcagaa ggaactgcct
    38521 ctcttatctt tgcggaaacg tcattttatg ctgaaatggg tggacaggta gctgactacg
    38581 gacaaatctt ggatgagtca ggtaaggttg tggctactgt gaccaatgtt cagaaagccc
    38641 caaatggtca agcccttcat acagttgaag tccttgcacc gcttgccttg aaccaagaat
    38701 ataccttggc aattgatagc aatcgccgtc accgtgtcat gaaaaaccac actgcgactc
    38761 atttgcttca cgctgccctt cacaatatcc ttggaaacca cgcaacacag gcaggatctc
    38821 ttaacgaagt tgaattcctt cgctttgact ttacccactt ccaagctgta actgctgaag
    38881 aattgcgtgc gattgaacag caagtcaacg aaaaaatctg ggaagctctt gaagttaaga
    38941 cagttgaaac ggatattgac actgctaaag aaatgggagc tatggccctc tttggtgaga
    39001 aatacggcaa ggaagttcgt gtcgtgacta tcggtgacta ctctattgaa ctttgtggtg
    39061 gtactcatgt tggcaacact tctgagattg gtctcttcaa aattgtcaaa gaagaaggaa
    39121 tcggttcagg aactcgccgt atcttggcag tgactggtaa ggaagccttt gaagcctatc
    39181 gtgaacaaga ggatgctctt aaagctgtcg cagcaatctt gaaagcacct caagtcaagg
    39241 aagtacctca caaggtagaa ggacttcaag aacaacttcg tcaacttcaa aaagaaaatg
    39301 ctgagttgaa agaaaaagcc gcagctgcag ccgcaggcga tatcttcaaa gatgctaagg
    39361 aagtcaacgg tcatcgttac attgctagtc aagtgtctgt atccgatgcc ggtgcccttc
    39421 gtacttttgc agataactgg aaacaaaaag actactctga tcttcttgtc ctagttgccg
    39481 ctatcggtga caaagtcaat gtccttgtag caagcaagac aaaagacctt catgcaggaa
    39541 accttgtcaa agaattagca ccaatcatcg atggacgtgg tggtggtaaa ccagacatgg
    39601 ccatggcagg aggaagcaac caagctaaga tccaagaatt gttggatgca gtagcaggta
    39661 aattgtaatc aagtaaagat ctatccattt gggtaggtct ttttgtgaat acaaaaaagc
    39721 caaatccgct tggacctagc ttggttatta tgagctatta gatggtattg actgcccaga
    39781 cacttacgga tctagctgag acagggaatt gtccataacc ttcctcatca attgtaactt
    39841 gaccttggtg gttaccaagt aaatctacaa aggtttgatt agtccattct tgaccgacaa
    39901 acattgactt gctgttttct tggtcatttg agataaggac tgcgattggg gattgatttt
    39961 cagcacctga acgtacccaa ccgatacagt tagcatggtc aaagtagtca ttttgttctc
    40021 cataggccaa gtcttttcgg atggctagga ggcggtcaag gatttctttg aaatcttctt
    40081 gagcatactg gcctgaaatc ccatagtagt ctccgtaaaa gacacatgga aggccgtctt
    40141 ggcgtaacaa aatgagggca taggctgctg gcttgaacca ttcttcaacg gtagactcaa
    40201 gggcttgtcc tcgttgggta tcgtggttgt cgacaaaagt cacagccttg tcaggcttga
    40261 gttcaaccag gctatctgtg aaaatgccac gaaggtcata gtttgcgcca gcttgactgg
    40321 cttcaaagag attctggtgg agacgaacat cgacaaggtc aaagtgttct tccgtttttt
    40381 cgagatagtc cagattggct tccttgtctg ggttccaaaa ttcaccaaaa acatagaaat
    40441 cgtcaccgta tttttccttc atatcgcgga tgaagttgcg cataaagaaa gagtcaatat
    40501 gcttaacggc atccaaacgg aaaccagcta caccagtcgt ttccatgaac caatcagccc
    40561 agtcatagat gttttggatg acttcaggat gtttaaagtc taggtcggca tacatgaggt
    40621 agtcgtagtt tccgttttcg ttatcgacca attcctcgtt agcccagccc ttgttgtccc
    40681 cttggatcag ataaatccca gatttactgc gtttggcatc gtagtctgta ccggtgaagt
    40741 ggtaccaatg ccagtggaag ccattatagg tatcttggcg accatcgaag gtaaaactag
    40801 tccagccatt gatggtgaag ggttctccaa gttcaactgt acggtctaca ggatcaactt
    40861 cgataacctg aaaggcttcc ctgttatcgg cagcagcctt gtggttgaga actacatcgg
    40921 ccataggttg aattccctgt tctttaaggg cttgaatggc ttgaagatag tcttctttga
    40981 aaccatactt ggtgcggaca gtcccttttt ggttgaactc tcctaagtca aataagtcat
    41041 agaccccata gccgacatct ttttcgttgg ttgccttgaa ggctggtggc atccagacgt
    41101 gactgatccc cagatgagct aggtgtggag cattttcagc cagacgcgtc cagtgttgac
    41161 cgtcgtgggg cagataccat tcaaagtatt gcatgagtgt ttgattttgc atgatgtttc
    41221 ctcttacttg tcaatcttgt tctttattct atcataaagt atctctcggc gcaaacgttt
    41281 gcgtaagata gaaggaaact attttaacta cttaaaataa agtattgatt tttttgtatc
    41341 aaagtgctag tatagcgatg tataatacag ataaagatag gagttgtccc atgattgaat
    41401 ttcaaaatgt tagtaagttg tatggtgata aagaggcctt gagtaatctc aatttgcaga
    41461 ttgaaaatgg agagattatg ggcttgattg gtcataatgg ggctggaaaa tcgaccacca
    41521 taaaatccct agtcagtatc atttcaccca gcagtggtcg tattttggta gacggtcagg
    41581 agttatcgga aaatcgcttg gcgatcaaac gaaagattgg ctacgtagca gactcgcctg
    41641 acttattttt acgcttaacg gccaatgaat tttgggaatt gatcgcttca tcctatgatc
    41701 tgactagctc tgacttggag actagtctag ctaggctatt gaacgttttt gattttgctg
    41761 aaaaccgcta tcaggttatt gaaactcttt ctcacggaat gcgtcagaaa gtctttgtca
    41821 ttggggcact cttgtctgct cctgatattt gggttttgga cgaacccttg actggtttgg
    41881 atccccaggc cgcctttgat ttgaagcaaa tgatgaagga acatgcacaa aaaggcaaga
    41941 cggtcttgtt ttcaactcat gtccttgagg tagccgagca agtctgtgat cggattgcta
    42001 ttttgaaaaa ggggcatttg atctattgtg gtagtgtaga gaacttgagg aaagaccacc
    42061 cagaccagtt tttggaaagt atctacctta gtcttgctgg tagaaaagag gaggttgcgg
    42121 atgcgtctca aggtcattaa aaaattagtt gatatcaata tcctctattc atctcaagaa
    42181 gctaatctgg ctaatctacg aaagaagcag gctaagaatc ctgggaaaaa agtaaatgtt
    42241 tctgctagag tcctaagttc ttacattttt tccagtctct tgatgctcat ctgttttagt
    42301 aatatagcca ttcattttcc ttttgaggaa atgcctattt attttagctc gatggttgct
    42361 attttactgg tgctggcctt ttcaacttct ttcactgcct tttacaatgt cttttatgag
    42421 agtaaggacc tggcctccta taggccctat gcctttaaag aatcagagat tataatggcc
    42481 aaaggtctgt ctgtcctctt gccagctcta actggaattg taccaatcct agcttatttt
    42541 ctagccctct atattagtct agctccttct ctttggctgg gtttgccttt gatgctactg
    42601 tccttgacct tattatttgt ctctgttact ttagtgacgg tagtggcagt acatttcttg
    42661 gctcagacta gggtcttcag aaagtatcag tctatttttt cgaatgtgat gattgggata
    42721 ggagttctca tacctttaat atttatcttc tttcttcagt cgacttttgg aagtattgtt
    42781 gacaaagtta gagacattcc atttctcctt tatcctcttc atatctttta caaaatagca
    42841 gtggagcctt tttcgacaga agccttagtg ggtctgctcg cttggatagg actaactctc
    42901 ttcctgcttt atctgaccaa aaagaaggtc cttcctcgtt tttatgacgt gatcctgctt
    42961 aacagtgagg agaaggtcaa aaaagaacgt cgcagcaagg agaggatttc aactactaaa
    43021 aagggctttt tccgtatggt tttacgctac cacctcaccc tcttgggaca ggggactggt
    43081 gtgattacag tgctttttac aagtgctttc cttccttatc tcatgatgat cagtctgatt
    43141 tccaaaatcc gagattctca gatagttcca gacattcatc ctccatactg gttacccttg
    43201 ttttttgtag gagtgtttat agcagttgtc aataacaata tcaccagcct gcattcaatt
    43261 gccttgtcct tggagaggga aaatgttgat tttctgaaga gtttaccctt tgactttgct
    43321 cgttatgtga aagtgaaatt ttggattatc tttgctgttc agtccttttt accagttctg
    43381 actttgctcg gtctttctct atatctaggc ttgtccatcc tttcgatgat ttaccttctt
    43441 gtagtctgga tcattgccag tgtcatcctt tcttgccacc attactttaa ggacgttaaa
    43501 aatctgtcaa ccaattggag tagcattacg gacctggtga atcgttcaaa tggcatagtc
    43561 gccatagttt tattgtttat ttatagtgca atcctgatgg cccttgtaat tgggagcata
    43621 ttcttggttc agtctctctc ccctatcctt gccatcaact tgggagtagg agctcttatc
    43681 gtcttgcttg ctcttgctat ttttggctat cattattacc tgtcacgcat attggcagaa
    43741 atagaaaaaa gatgagatag ttggttgctt gcttgataaa ttcaattcga caaacgcttt
    43801 tatagtttgt tagaatgtag ttgtaaatga ttaagattgg taatcaaaaa tatagggagg
    43861 aatgttttga ataagaaata taatatagtt ctattattgt tgtttatagt ttatttattg
    43921 ggatattttt caatttcaaa aacgttaatt cctataatgt gtgtgatcca agtatttttg
    43981 atagaacata tatttagagt tcgaaataga atgatgcaaa taggtgaaat tttaattatt
    44041 gttgcttcta taatattatt tattgatagt atattgagtt tgtaacaaaa ggcttctcta
    44101 taaaatcaaa ttttccagat acctactgaa gctgatttat ttcttcatct ttcttctact
    44161 acctttgtca ctaaatttga cagacacata ttgctgatac aacctctcta cctataatct
    44221 cacggttaac ctgaggctag tttcatagtt tgctatttga ttttcgttga taaaaagaaa
    44281 tgctcctcca agacggaaga gcatttttta ttgtgattct tacacattta tttcctagtt
    44341 ttgcaggaag tctagtatac cattttttaa aagaagagta aaaaagcaag ggtagtttct
    44401 tttttgagaa ttgtctaaaa gtttgatata atggtagtta tgaatagaat aagagtcagc
    44461 aaaagggttg aaaagaagct tgctaagggg ctagttttac tagaagccag tgatcttgag
    44521 aatgtcaatc ttaaggatca ggaagtagag gtgcagggtc aggaaggaaa ctttcttggg
    44581 actgcctacc tttctcagca aaacaagggc ttgggctggt ttgtcagcaa agacaaggtg
    44641 gccttcaatc aaactttctt tgaaacgttg tttagaaaag ccaaagaaaa gagaaacgcc
    44701 tactatcaag atgatttgac aactgccttt cgtctcttta atcaagaggg agatggcttt
    44761 gggggtctga cagtggacct ttatggcgac tacgccgtct tttcttggta taactcttat
    44821 gtttatcaga ttcgtcagac tatatcagaa gcctttagac aggttttccc tgaggtttta
    44881 ggggcttatg agaaaatccg ctttaagggt tttgactatg aatctgccca tgtttatggt
    44941 caagaagcac ctgacttttt cactgtttta gaaaatggtg tcctgtatca agtctttatg
    45001 aatgatggct tgatgacagg aattttccta gaccagcatg aggttcgcgg tagtttagtt
    45061 gacggcttgg ctatgggtaa atccttgctc aatatgtttt cctacacagc ggctttttca
    45121 gtagctgcgg ccatgggagg agctagccag acaacttctg ttgatctagc caaacgttca
    45181 cgagaattgt ctcaagcgca ttttcaggca aatgggctca gcacagacga gcatcgtttt
    45241 atagtcatgg atgtctttga gtatttcaaa tatgccaaac gcaaagactt gacctacgat
    45301 gtgattgtcc tagatccgcc tagctttgct cggaataaaa aacaaacttt ctctgtggcc
    45361 aaggattatc acaagttgat ttcccagagt cttgagattt taaatccggg agggattatc
    45421 attgccagta ccaatgctgc caatgtttcc cgtcagaaat ttacagaaca aattgataaa
    45481 ggctttgcag gaagaagtta ccagatttta aacaaatatg gtcttccagc agattttgcc
    45541 tataataaaa aagatgaaag tagtaattac ctcaaggtga ttagtatgaa ggttagtaaa
    45601 tgaaattaat cgtttcagta atgccaagaa gtttagagga ggctcaggct ctgggtgcca
    45661 cgaggtacct ggatgccgac atcattgaat ggcgtgccga ctatctgcct aaagaagcga
    45721 ttttgcaggt agctccagcc atttttgaaa aattcgcagg ccgtgagttg gttttcacgc
    45781 tacgaactcg ctccgaaggt ggagaaatcg acctttctcc agaagagtat atccatctaa
    45841 tcaaggaagt tgcgcaattc tatcaaccag actatattga ttttgagtac tatagctaca
    45901 aggatgtttt tgaggaaatg ctggacttcc caaatcttgt tttgagttac cataatttcc
    45961 aagaaacacc tgagaacatg atggaaatct tgtcagagtt gacgatccta aatccaaaac
    46021 ttgttaaggt tgcggtgatg gctcacacgg agcaggatgt cttagacttg atgaactata
    46081 cacgaggctt taaaaccctc aatcctgaac aggaatatgt gaccatttct atgggtaagg
    46141 tgggcaaggt ctctcgtatc actgcggatg tgactggttc gagttggtct tttgccagtc
    46201 tggatgaggt tagtgcccct gggcagattt ctctagctag catgaaaaaa atcagggaga
    46261 ttttggatga agcttgatgg ctatacacgt ttagctgcag ttgttgccaa tcctattaag
    46321 cattctattt ctcccttcat ccacaataga gcctttgagg cgacagctac caacggtgct
    46381 tatgtggctt gggagattga agcgagtgac ttggcagaaa cagtggccaa tattcgtcgc
    46441 taccagatgt ttggcatcaa tctgtccatg ccctataagg agcaggtgat tccttatttg
    46501 gataagctga gcgatgaagc gcgcttgatt ggtgcggtta atacggttgt caatgagaat
    46561 ggcaatttaa ttggatataa tacagatggc aagggatttt ttaagtgctt gccttctttt
    46621 acaatttcag gtaaaaagat gaccctgctg ggtgcaggtg gtgcggctaa atcaatcttg
    46681 gcacaggcta ttttggatgg cgtcagtcag atttcggtct ttgttcgttc agtttctatg
    46741 gaaaaaacaa gaccttacct agacaagtta caggagcaaa caggctttaa agtggacttg
    46801 tatgctttag aaaatgtttc tgaactgcaa gcaaggattg tcgagtcgga tttactggtc
    46861 aatgccacca gtgtgggcat ggatggtcaa tcatccccag ttcctgaaag catcaatttg
    46921 ccagaaacta tcttggtggc agatattatt tatcaaccct ttgaaacgcc atttttaaaa
    46981 tgggccagaa gtcagggcaa accagcggtt aatggtctgg gaatgttgct ctatcaagct
    47041 gcagaagctt ttcaactgtg gacaggcaag gaaatgccaa cagaagagat ttggcagtct
    47101 ttaacagaaa aataccaata aagaaaagga gattctccta tgaaaatcag aatcgatatt
    47161 cctcatcatc cttatgatat tcagattgaa aaaggttgtc tggctcaggc tggtcaatgg
    47221 ttgcgagaac tctggcaacc acaaaaggta gtcattgtga cagataacca tgtagcttct
    47281 ctttatgcag agaaggtcaa gctcagccta gaagatgctg gttttcaggt agctgttttt
    47341 gactttttag aaggggaaga aagaaagaat ttaaccactg ttcagaaagt ctatgaattc
    47401 ctagttaagc aggggttgac tcgtagcgat ggaatcgtgg ctctcggtgg tggtgtcgtt
    47461 ggggacttgg ctggttttgt agcctctacc tatatgcggg gcattcattt tgttcagata
    47521 ccgactagct taacagccca ggtggattct tctattggtg gaaagacggg tgttaacact
    47581 ccatttgcca agaatatggt aggaactttt gcccaaccag atggggtttt gattgaccca
    47641 cttgttcttg aaacgcttgg aaaaagagag ttgattgaag ggatgggtga ggttatcaag
    47701 tatggcttga ttgaggatcc agaactgtgg gctcttttga cggagctgga tggttctgtt
    47761 gagagcattc tggaacatgc agagaccttg attgaacatt cttgtcaggt taagcgcaag
    47821 atggtggttg aggatgagtt ggacaatggt gtacgccttt acctcaactt tggtcacact
    47881 attggtcatg ctattgaagc aactgccggt tatggtaagg tcatgcatgg tgaggctgtg
    47941 gccatgggca tggtgcagat ttccaaggtt gctgagaaaa aaggcctcat gccagctggc
    48001 ataactcagt ccattacaga tatgtgtcag aaatttggct tgcctgttga ctatgaaaac
    48061 tgggatgttg acaagcttta tcaggctttg actcatgaca aaaaagcgcg tggcaatacc
    48121 ttgaaattgg tcttggtacc agagcttggt tcagcgacca ttcacccagt ttctctggaa
    48181 gagatgaaag actacttggt aaaataagga gagtgtatga gatatttaac tgcaggagaa
    48241 tcacacggtc cccgtctgac agctatcatt gaaggaattc cagctggact acctttgaca
    48301 gctgaggata tcaatggcga ccttaaacgc cgtcagggtg gctacggtcg tggcggtcgt
    48361 atgaagattg agagcgacca agttgtcttt acttcaggtg ttcgccatgg gaagacgaca
    48421 ggggctccta ttaccatgga tgtcgtcaat aaggaccacc aaaaatggct ggatatcatg
    48481 tctgcagagg acattgaaga ccgccttaaa agcaaacgaa aaatcaccca tcctcgccca
    48541 ggacatgccg atttggttgg gggcatcaag taccgttttg atgatttgcg aaattctttg
    48601 gagcgttcat cagctcgtga aaccaccatg cgggtggcag ttggtgcagt agccaaacgc
    48661 ctcttggctg agctggatat ggagattgcc aaccatgtcg tggtctttgg tggcaaggaa
    48721 atcgatgttc ctgaaaatct gacagtcgct gaaattaagc aaagagctgc ccagtctgaa
    48781 gtttctattg ttaaccaaga acgagaacag gaaatcaagg actatattga ccaaatcaaa
    48841 cgtgatggtg ataccatcgg tggggttgtg gagacagtcg tcggaggcgt tccagttggt
    48901 cttggttcct atgtccaatg ggatagaaaa ttggatgcaa gattggctca agctgttgtc
    48961 tctatcaatg cctttaaagg ggtggaattt ggtcttggct ttgaggctgg ttatcgtaaa
    49021 ggcagccaag ttatggatga aattctctgg tctaaagaag acggttatac tcgccgtacc
    49081 aataatctag gtggttttga aggtggtatg actaatgggc aacccatcgt tgttcgtggg
    49141 gtcatgaaac ccattcctac tctttataaa cctcttatga gtgtggatat cgaaacccac
    49201 gaaccttaca aggcaaccgt ggagagaagt gatccgactg ctcttccagc tgcaggaatg
    49261 gtcatggaag cagttgtagc aacggttctg gcgcaagaaa tcctcgaaaa attctcatca
    49321 gataatcttg aggaactaaa agaagcggta gccaaatacc gagactatac aaagaactat
    49381 taaggagttc ctatggcaaa aacaatctat atcgcaggtc ttgggttgat tggagcctct
    49441 atggcacttg gtatcaaacg cgatcatcca gattatgaaa ttttaggtta taatcgtagt
    49501 caagcttcga gagatatcgc cttgaaagaa ggcatgattg accgtgcaac ggatgatttt
    49561 gctagttttg ctcctttggc agatgtcatt atcctcagct tgccaatcaa acaaactatt
    49621 gctttcatta aggagttggc caatttggat ttgcgagaag gcgttattat ttcagatgct
    49681 ggttcgacca agtcaaccat tgtggatgcg gcggagcagt atttggctgg caagtctgtt
    49741 cgctttgtcg gggcccatcc catggctggt agtcacaaga caggggctgc ttcggcagat
    49801 gtcaatcttt ttgaaaatgc ctattatatc tttacacctt caagcctgac aagtcaggac
    49861 acgcttaagg aaatgaagga tctgctttca ggtcttcatg ctcgttttat cgagattgat
    49921 gccaaggagc atgatcgtgt cacttctcag attagccatt ttcctcatat tttggcttct
    49981 agtctcatgg agcagactgc ggtctatgct caagagcatg agatggcaag gcgctttgcg
    50041 gcaggtggtt ttcgagatat gacccgaatt gcggaaagcg agccaggaat gtggacctcc
    50101 attctcttgt ccaatagcga gaccattctg gatagaattg aggatttcaa ggaacgtttg
    50161 gaagtgattg gtcaggccat tagtaaggga gatgaagagc aaatttggaa cttttttaac
    50221 caagcgcgtg aacaacgcca gaccatggaa atccataagc gtggtggtgt ggatagctct
    50281 tacgacctct atgttgacgt tcctgatgaa gaagatgtca tcctgcggat tttggaactg
    50341 ctacgtggga cttccttggt taacatccac atcaacgagg aaaatcgtga ggatattcac
    50401 ggaatcctac aaatttcatt taaaaatgct caagacttgg aaagagctga gcatctcata
    50461 acagaaaata ccgactatac agtcgtcatc aaataaggag aagaacatgt caaatattta
    50521 cgatagtgca aacgaactca gtcgcggtct acgcggatta ccagaataca aggctgttaa
    50581 agcagctaaa gatgcgattg cagcagatgc tgaggcaagc aaaatcttta cagaatatct
    50641 tgcctttcaa gaggaaattc aaaaactagc acatacaggt caaatgccag atgcgtcctt
    50701 ccaagctaag atggaaggct ttggtaaaca gattcaagga aatagcctct tgtcagaatt
    50761 ctttaccaag caacaacaat tggccattta cctttctgac attgaaaaaa ttgtttttga
    50821 accagtttca gaattgctga aataagaaaa gaacgatcct aaagtcagga atttttaagg
    50881 aatttctggc tttttatgat aaaataggta aaagtattgc aagtatgagg tccagtatga
    50941 aactaaaaac aaacattcgc catttacatg gtagtatccg cgtcccaggt gacaagtcta
    51001 tcagccaccg ttccattatc tttggaagtt tggctgaggg tgagaccaag gtttatgata
    51061 ttctgcgagg tgaagacgtt ctttcgacca tgcaggtttt tcgtgacctt ggtgttgaaa
    51121 ttgaggataa agatggggtt attaccattc aaggtgtagg catggctggc ttaaaagcgc
    51181 cacaaaatgc ccttaatatg ggaaattctg gcacctcgat tcgcctgatt tcaggtgtcc
    51241 ttgctggtgc agatttcgaa gtagagatgt ttggagatga tagtctttcc aaacgtccta
    51301 tggaccgtgt gacccttcca ctgaaaaaaa tgggcgtcag catttcaggg caaactgaac
    51361 gagacttgcc tccccttcgc ttaaaaggga cgaaaaacct aagacctatt cattatgagt
    51421 tgccaattgc ctctgcccaa gtcaagtcag ccttgatgtt tgcagcctta caagctaagg
    51481 gggagtcagt tattatcgaa aaagagtgca cccgtaatca tactgaagat atgttgaaac
    51541 aatttggtgg tcatttaagt gtggacggta agaaaatcac agtccaaggg ccacaaaaat
    51601 tgacaggaca gaaggtggtc gtaccaggag atatttccag tgcagccttt tggttagtcg
    51661 caggtttgat tgttccaaat tctcgtctag tgctgcagaa tgtggggatc aacgaaactc
    51721 gcaccggtat tattgatgtc attcgtgcca tgggtggaaa attggaaata actgaaatcg
    51781 atccagtcgc taaatcttct accttgactg ttgagtcttc tgacttgaaa ggaacagaga
    51841 ttggtggcgc tttgattcca cgattgattg atgaattgcc cattattgcc ctgcttgcga
    51901 ctcaagccca aggtgtaaca gttatcaagg atgctgagga gctcaaggtc aaggaaacag
    51961 accgtattca ggttgtggca gacgccttaa atagtatggg agcagatatt actcctacgg
    52021 cagatgggat gattatcaaa gggaaatcag ctcttcacgg tgctagagtc aatacgtttg
    52081 gtgaccaccg tatcggcatg atgacagcta tcgcagccct cttggttgca gatggagagg
    52141 tggagcttga ccgtgcagaa gccatcaata ccagctatcc tagtttcttt gatgatttgg
    52201 agagcttgat tcatggctaa ggtgttatta gggtttatgg gggctggaaa atcgactatt
    52261 gcaagaggct tggaccctaa ttaccttgat atggatgctc tgattgagaa gcgcctaggt
    52321 atgtccattg cgaatttttt cgctgaaaag ggagaagcag cctttcgtca ggtagaatca
    52381 gaagtcctag ctgatttact acaaacagac caagtcgtgt caactggagg aggagtggtt
    52441 atttctcaga gaaatcgtga cttactcaag actaatacag ataacatcta cctgaaagca
    52501 gattttgaaa ccctctacca acgtatcgca gctgataagg acaatcagcg accgcttttt
    52561 ctaaataata gcaaggaaga actagtagct atttttcaag aaagacaggc ttggtatgag
    52621 gaagtggcta gtcgggtttt ggatgtgacc aagctaagcc cagaggaaat tatagaggaa
    52681 ctaagatgaa aattgcttat ctaggtccca agggatcatt ttcacaccac gttgtgcaga
    52741 tagcttttcc tcatgaggaa ttgcaggctt ttgctaacat tacagatgtc atcaaggctt
    52801 atgagcaagg attagtggac tattctgtgg tgccagttga aaattctatt gagggtagtg
    52861 ttcatgaaac cttggactat ctttttcatc aggctcacat ccaagcagta gcagaaatcg
    52921 ttcagcctat tcatcagcag ttgatggtgg ttccaggcca tactaagatt gaaaagattt
    52981 tttcacatcc acaggccttg gctcaaggaa agaaattcat cgatgaacaa tatccagagg
    53041 ctcaaatcga ggtaacagct agtacagctt atgcggcccg ttttatttcc gaacatccag
    53101 accagccctt tgcagcagtt gcacctagaa gttctgctga agaatatgga ttggaactga
    53161 ttgccgagga tattcaggaa atggaagcca atttcacacg tttctgggtt ctaggagctg
    53221 aaaagcctag tattcccttg caagcacaaa ctgaaaagat gagtttggcc ttgacattac
    53281 ctgacaacct tccaggtgca ctttataagg ccctgtcgac ctttgcttgg cgaggaattg
    53341 acttgacaaa aattgaaagt cgtccactca agacagcact gggtgaatac tttttcatta
    53401 tcgatgtgga ttataccgat aaggacttgg tccactttgc ccaaaaagaa ttagaagcga
    53461 ttggaatcca gtataaaatt ctgggtgcct atcctattta tccaatatca gaccatggaa
    53521 aggagagaag atgagtaaag aaaatccctt aagtcatcat gagcagttgc gttatgatta
    53581 tttgctaaaa aatattcact atctcaatga gagagaaaaa aatgagtttg cctatttgca
    53641 agaaaagcta actcttgcta ggggaaatag tagctctagc ttggaacaag aaagagaaga
    53701 gcaggttgac ttaccaagct atgcgaaccg gagtcgctca caatccaaat cacaagcact
    53761 ctctttccct ccaaaaaaga aaagacggaa gctccgtctt aaacgaattt ttatggtgat
    53821 tttttcactt ttggtctgtg tggctttggc catggtattc atgtttttgc gtggttacca
    53881 agatgctagc gcaaagaaaa ctgctgatgc ccgggcagct caagtagaag tctttaatgg
    53941 tcaggacact agagatggag ttaatatttt aatcatgggt actgatggtc gaatcggcca
    54001 gaacagtgtt gagacacgaa ctgactctat tatggtatta aatgtcgggg gctcagataa
    54061 gaaaatgaag ctagtcagtt tcatgcgtga taatttggtc tatatagatg gttatagtca
    54121 agtgattaac ggtagaaaac agacagataa caagttaaac gtagcctacg agttaggaga
    54181 acaagagggg caaaaagggg cagaaatggt tcgccaagtc ttgaaagata attttgactt
    54241 ggacattaag tactacgcct tggttgattt ccaggccttt gccacagcga ttgacacgct
    54301 tttccctgat ggggtgacga ttgatgctca attttcaaca ttgaatgggc gtcccctaac
    54361 agaagctaca gtcggagatg atttatacgc taccgagact gagtctccaa cccaaaccat
    54421 taaagtcgga aaacagcaga tgaatggctc gaccctgctc aattatgctc gtttccgtga
    54481 tgatgatgag gcggattacg gccgtacaaa aagacagcaa caagttttaa cagcaatttt
    54541 agagcaaatt aaagatccca ctaaactttt cactggttct gaagctcttg gaaaggtttt
    54601 tgctatgacc tcaaccaacg taccctatac tttcctccta acaaacggtt tatctgtttt
    54661 ggatggagca aaaaatggta ttgaaaaatt gacgattcca gaactgggtg actgggtaga
    54721 tgcctatgat gtttatggag gcttgggctt gctggttgat caaaacaaat atcaaaccaa
    54781 gctcgctcaa atgggcttga gataagataa tactcaatga aaatcaaagt gcaaactagg
    54841 aagctagccg caggctgcta aaaacacagt tttgaggttg tagataagac tgacgaagtc
    54901 agttacctat acctacggca aggtgaagct gacgtggttt gaagagattt tcgaagagta
    54961 taagacagaa aaatcaaagt ttgatagcta tttggatagc agtcaggctt tgatttttta
    55021 cagtctgcaa tagattttca ccccttgttt gtggtataat gaaacgatac gatagaaaga
    55081 ataatgaaca atatgactga tttaaaagca attcaggctc gtagtctgga gatggctgaa
    55141 tattttgtgg ccttttgtaa agaacatgat ttgctctgtt atctctgtgg cggaggcgct
    55201 attggtgccc ttcgaaacaa gggatttatt ccttgggacg acgacctaga cttttttatg
    55261 cctcgtaaag attatgagaa attagcagaa ttatggcctc gttatgcaga tgaacgttat
    55321 ttcttgtcaa agagtcacaa ggattttgtt gatcgtaatc tttttattac cattcgtgac
    55381 aaggaaacca cctgtatcaa gccttatcag caggatttgg atttgccaca tggtctggcc
    55441 ttggatgttt tgcctttgga ttattatccg aaaaatccag ctgagcggaa aaaacaggtt
    55501 cgttgggcct tgatttattc actcttttgt gcgcaaacta ttccagaaaa gcatggtgct
    55561 ctcatgaaat ggggaagtcg cattttactg ggtttgactc caaaatctct ctgttatcgc
    55621 atctggaaaa aagctgagaa agaaatgact aagtatgatt tggctgattg tgatggcatt
    55681 acagaattat gctcaggtcc tggctacatg agaaacaagt acccaatcac atcttttgaa
    55741 gacaatcttt tcttgccatt tgaaggaaca gagatgccta ttccaatcgg ctatgatgtc
    55801 tatctcagaa ctgcttttgg ggattatatg acgcctccac cagcagacaa gcaggtaccg
    55861 catcatgatg ctgtcatcgc tgatatggat aagtcttata cagaatacaa gggagaatat
    55921 ggtggctaag aaaaaaatct tattttttat gtggtctttt tctcttggag gtggtgcaga
    55981 gaagattcta tcaaccattg tttcaaatct ggatccagaa aagtatgata ttgatattct
    56041 tgaaatggag cactttgaca agggatatga atctgttcca aagcatgtac gcattttaaa
    56101 atcccttcaa gattatcgcc aaaccagatg gttacgagct tttttgtgga gaatgagaat
    56161 ttattttcca agactggctc gtcgtttgct tgtaaaagat gattatgatg ttgaagtttc
    56221 ttttaccatt atgaatccac cactgttgtt ctctaaaaga agagaagtca agaagatatc
    56281 ttggattcat ggaagtattg aagaacttct taaggatagc tctaaaagag aatcacatag
    56341 aagccagttg gatgctgcga atacaattgt agggatttca aaaaagacca gcaattctat
    56401 caaggaagtt tatccagatt atacttctaa attacagaca atctacaatg gatatgattt
    56461 tcagactatt ctagaaaaat ctcaagagaa gatcgatatc gagattgctc ctcaaagtat
    56521 ctgtactatc ggacggattg aggaaaataa gggttctgac cgtgtagtgg aagtgatacg
    56581 attattacac caagagggaa aaaactatca tctctatttt atcggggctg gtgatatgga
    56641 agaggaactg aaaaaacgag tcaaagagta tgggattgag gactatgtac atttccttgg
    56701 ttatcaaaaa aatccttatc agtatctatc tcagacgaaa gttcttttgt ctatgtctaa
    56761 acaagaaggt tttcctggag tgtatgtgga ggccttgagt ctgggactcc cttttatctc
    56821 tacgaacgtt ggaggggctg aggaattatc ccaagaagga cgatttggac aaatcattga
    56881 gagcaatcaa gaggcagctc aggcgattac taattacatg acttctgcct caaactttga
    56941 tgtcgatgag gctagccaat tcattcaaca atttacaatt acaaaacaaa tcgaacaagt
    57001 agaaaaacta ttagaggagt agcatggaaa ctgcattaat tagtgtgatt gtgccagtct
    57061 ataatgtggc gcagtaccta gaaaaatcga tagcttccat tcagaagcag acctatcaaa
    57121 atctggaaat tattcttgtt gatgatggtg caacagatga aagtggtcgc ttgtgtgatt
    57181 caatcgctga acaagatgac agggtgtcag tgcttcataa aaagaacgaa ggattgtcgc
    57241 aagcacgaaa tgatgggatg aagcaggctc acggggatta tctgattttt attgactcag
    57301 atgattatat ccatccagaa atgattcaga gcttatatga gcaattagtt caagaagatg
    57361 cggatgtttc aagctgtggt gtcatgaatg tctatgctaa tgatgaaagc ccacagtcag
    57421 ccaatcagga tgactatttt gtctgtgatt ctcaaacatt tctaaaggaa tacctcatag
    57481 gtgaaaaaat acctgggacg atttgcaata agctaatcaa gagacagatt gcaactgccc
    57541 tatcctttcc taaggggttg atttacgaag atgcctatta ccattttgat ttaatcaagt
    57601 tggccaagaa gtatgtggtt aatactaaac cctattatta ctatttccat agaggggata
    57661 gtattacgac caaaccctat gcagagaagg atttagccta tattgatatc taccaaaagt
    57721 tttataatga agttgtgaaa aactatcctg acttgaaaga ggtcgctttt ttcagattgg
    57781 cctatgccca cttctttatt ctggataaga tgttgctaga tgatcagtat aaacagtttg
    57841 aagcctattc tcagattcat cgttttttaa aaggccatgc ctttgctatt tctaggaatc
    57901 caattttccg taaggggaga agaattagtg ctttggccct attcataaat atttccttat
    57961 atcgattctt attactgaaa aatattgaaa aatctaaaaa attacattag aacgggggtg
    58021 accaagtgat tgatgggaaa cgattattat ttagtttgac catagtcagt tatgccttga
    58081 cgctagtaag tggaattgtg tatctgttta ataataataa tgttagctta ctttctactt
    58141 tattgttctt gttggttagt agcttaattg cttgttggaa tgatatcaag tattacttaa
    58201 tccattttat tttctattta accatttttg tatttctggt atcaagaccg accattgatt
    58261 attttaggga tggtgctttg gatacctatc atccaatagc ctatcgtttt gcctttatag
    58321 ttgtcatggt ttcgattctg ggcttgacca caggaggcat tctggctcgt tacttcatag
    58381 ctaggaagaa aataaaagta gcaaatatag gaaattctct aaaagaggtt tatatcaagc
    58441 ggttacgctt tgtatcacta ggagtttttc ttctaaccta tcctttctat ttcattcggt
    58501 tatttgaacg gctcttgtat cgtttgcaga cttcctacta tgcctactat gcaaattttg
    58561 aaagtaaact gccttatttt acctacattt tgtctacctt tacggtctat gcaatgtgta
    58621 tgtatctggc aaccaagcca aagaaattgc aggccacagc agtgcttgtc tcctttattg
    58681 cagctaatac tattcatttg gcaattggga cacgaaatcc ctttatttta agtattttat
    58741 ttgcttttgt ttattacttt atgcgggagc aaactgaaaa aggaaaatgg attgggttta
    58801 aagaaaagtt agcgattttt gtaggttctc ctattctcat gttagcgatg ggagtactca
    58861 attatgtacg ggataatgtc caagtttctc atacaggttt ctgggatatc ttacttgact
    58921 ttatctataa acaagggact agttttggtg ttctggctcg aggttttcta tttaacagta
    58981 gcctccctta ccgagatttc cgtaatttta cttttggtcc tgttcttgat tattttgcaa
    59041 gggggagttt gggagccatt ttcggaggaa aagcctttga acatacaacc aatagtgtgg
    59101 aactagctat tgatagtaat agttatgccc acaatctatc ctatcttgtc ttgaacaagg
    59161 aatacttgaa agggcatggt atcggaagta gttatatcat ggagttgtat accgactatg
    59221 gtatgattgg agtctttctg cttagtttct tactcggcgt attatttata gccatgctgc
    59281 aagtagccta tcgctcaagg acaatcctat ttgctttatc cctactcatc ttgaataatc
    59341 tattctttat gccaagaagc agcttttcag aaagtttctt caatttattt acaatgcaat
    59401 tctggggaat tgttcttgtg attatatttg tagcaaaaat gcttacaaag gaaaactagt
    59461 atctactaaa caaaggagaa aaaaatcatg tttgaacatt attcagtagc tgatttgttt
    59521 gcaaatcttt ataaaaagcg aaaagcaaat attttagctc tcatcgcttt atttgctctc
    59581 attgctgtac catttacaat taaagcagtt aggaataaaa acactgtcaa agatacaaca
    59641 agttattcaa cttatcttat ctataaaatc actcctccaa aagagtcggc caaaacgatt
    59701 ttgaatcatc aaattggtgg ttatagtgat ttttatggga aattgattga tggtaatttg
    59761 aatggagctt atcttttcaa tgatgtagaa cccagtgagt tgaaaaaaat tgccagtgaa
    59821 ttagacacga cagaaacaac cttgaaaaat tcaacgaatg actattggtg gaaaaaattg
    59881 accgtctact atatgattga cgatgcaggg gttggtgtga aaattttgac atcaagtaaa
    59941 gatgccaatg acttgttaga gaaaaaaatt gatgggttga ttgagaaatt taaacatgcc
    60001 tatgcaaatg tgaaaattga aaaactggaa accatcaact ctaaagaatt gaacgcaaat
    60061 ggtgaaacag cgcttggctt aaatgtgaaa aatctgattc ttcgtttagt tgttattgga
    60121 gtggtttgtg tgattttggt tgtgatggga aatgtgttag tttatctctt taatccaaca
    60181 atcaatagag taggtgattt ttctcagtat caaattgatt ttgtaacaga gattacaaca
    60241 attgctaacc tagcagatgt tttgtcatac aaaaatactg gacaggaatt gaccatcgtt
    60301 agctcaaata aagctatcct agataaattg aaacagagtc aagaagcttt aaaaggaatg
    60361 cattttgtag atttacagga tgtatcatct cttttggaaa gagatacagt ccttcttgtt
    60421 gaagagtacg gagtgactcg ttataagaaa tttgagcaaa gtcttcaaat tctcagaaac
    60481 ttaaatcgtt ctatccttgg tgtagcaacc tttaaattat aagtattctg atgtataagg
    60541 tcttcaaaat cggctaagag ctgattttga aggctttttc tatctgtctg cagaaatttt
    60601 cttttggagt ctcctataga aagaccctag ggaaaatcta tccgtataga ggagccttct
    60661 tttgataaaa tcgtaaaaat ctagtataat agatagaact gaaagtatga ggttactagc
    60721 aatgaaaatg aaacaaatta gtgatacaac tttaaaaatc acgatgtctt tagaggattt
    60781 gatggatcgt ggaatggaga ttgctgactt tctcgttcct caagaaaaaa cagaagagtt
    60841 cttttatgct atcttggatg aactagagat gcctgatagc tttctggata caggcatgtt
    60901 gagcttccgt gtgactccaa aacctgataa ggtagatgtc tttgtgacca agtcaaagat
    60961 tgaccaaaat ctagattttg aagacttatc ggatttgcca gatatggaag aattggctca
    61021 aatgtctcca gatgaattta tcaaaaccct ggaaaaaagc atcgcagaca aaaccaagga
    61081 tgatatcgaa gccattcaat ctcttgagca agttgaagcc aaggaagaag agcaagagca
    61141 ggctgaacaa gaagctgaga gtaagaaaga accttacatc tactacatcc tttcttttgc
    61201 taagttggct gacttggtag tttttgccaa gacagtgact tttgaaatgg aaacttctga
    61261 actctacaaa atgaacgagc gctattattt gaccatttta gtggatattg aaaatcatcc
    61321 aagcccatat ccagcttggc tgttggcccg tatgcgcgag tttgcagacg atagtgatat
    61381 cagtcgctca gtcttacaag agtatggtca agtcttgatg agtcacgatg cagtgctcaa
    61441 tctgcaaaaa atcggctaat cctttctgga aagctatttt cagattttaa gaagagcgaa
    61501 tcgtctgatt cgttttttct ttttatactg aaatagtgat ttactataat aggaattttc
    61561 acaaaattct gttataatgg ctatattaga aaatttcgag gagataaaga tgacagttaa
    61621 aattgcttta ctaggatttg gtaccgttgc aagtggtgtg cctttcctcc taaaggaaaa
    61681 tggaggaaaa atcaatcaat cagcacattc agatatcaaa gttgctaagg tattggtcaa
    61741 ggatgaagat gaaaaaaatc gcttgcttgc agcagggaat gactttaact ttgtaaccaa
    61801 tgtggatgat attttatcag accaggatat tactatcgta gtggaattga tggggcgtat
    61861 tgagcctgct aaaaccttta tcactcgtgc cttggaagct ggaaaacacg ttgttactgc
    61921 taacaaggac cttttagctg tccatggcgc agaattgcta gaaatcgctc aagctaacaa
    61981 ggtagcactt tactacgaag cagcagttgc tggtgggatt ccaattcttc gtactttagc
    62041 aaattccttg gcttctgata aaattacgcg cgtgcttgga gtagtcaacg gaacttccaa
    62101 cttcatggtg accaagatgg tggaagaagg ctggtcttac gatgatgctc ttgcggaagc
    62161 acaacgtcta ggatttgcag aaagcgatcc gacgaatgac gtagatggga ttgatgcagc
    62221 ctacaagatg gttattttga gccaatttgc ctttggcatg aagattgcct ttgatgatgt
    62281 agcccacaag ggaatccgca atatcacacc agaagacgta gctgtagctc aagagtttgg
    62341 ttacgtagtg aaattggttg gttctattga ggaaacttct tcaggtattg ctgcagaagt
    62401 gactccaacc ttcctaccta aagcgcaccc acttgctagt gtgaatggcg taatgaacgc
    62461 tgtctttgta gaatctatcg gtattggtga gtctatgtac tacggaccag gtgcgggtca
    62521 aaaaccaact gcaacaagtg ttgtagctga tattgtccgt atcgttcgtc gtttgaatga
    62581 tggtaccatt ggcaaagact tcaacgaata tagccgtgac ttggtcttgg caaatcctga
    62641 agatgtcaaa gcaaactact atttctcaat cttggctcca gactcaaaag gtcaggtctt
    62701 gaagttggct gaaatcttca atgctcaaga tatttccttt aagcaaatcc ttcaagatgg
    62761 caaagagggt gacaaggcgc gtgtcgttat catcacacac aagattaata aagcccagct
    62821 tgaaaatgtc tcagctgaat tgaagaaggt ttcagaattc gacctcttga ataccttcaa
    62881 ggtgctagga gaataagatg aagattattg tacctgcaac cagtgccaat atcgggccag
    62941 gttttgactc ggtcggtgta gctgtaacca agtatcttca aattgaggtc tgcgaagaac
    63001 gagatgagtg gctgattgaa caccagattg gcaaatggat tccacatgat gagcgtaatc
    63061 tcttgctcaa aatcgctttg caaattgtac cagacttgca accaagacgc ttgaaaatga
    63121 ccagtgatgt ccctttggcg cgcggtttgg gttcttccag ctcggttatc gttgctggga
    63181 ttgaactagc caaccaactg ggtcaactca acttatcaga ccatgaaaaa ttgcagttag
    63241 cgaccaagat tgaagggcat cctgacaatg tggctccagc catttatggt aatctcgtta
    63301 ttgcaagttc tgttgaaggg caagtctctg ctatcgtagc agactttcca gagtgtgatt
    63361 ttctagctta cattccaaac tatgaattac gtactcgcga cagccgtagt gtcttgccta
    63421 aaaaattgtc ttataaggaa gctgttgctg caagttctat cgccaatgta gcggttgctg
    63481 ccttgttggc aggagacatg gtgaccgctg ggcaagcaat cgagggagac ctcttccatg
    63541 agcgttatcg tcaggacttg gtaagagaat ttgcgatgat taagcaagtg accaaagaaa
    63601 atggggccta tgcaacctac ctttctggtg ctgggccgac agttatggtt ctggcttctc
    63661 atgacaagat gccaacaatt aaggcagaat tggaaaagca acctttcaaa ggaaaactgc
    63721 atgacttgag agttgatacc caaggtgtcc gtgtagaagc aaaataaaga atagaagata
    63781 ggatggggaa actcttgacc agagggtttc atatcctttt tgtgaaaaga agtttatact
    63841 caatgaaaat caaagagcaa actaggaagc tagccgcagg ctgctcaaaa cagtgttttg
    63901 aggttgcaga tagaactgac gaagtcagta acatatatac ggtaaggtga cgctgacgtg
    63961 gtttgaagag attttcgaag agtattagtt aaaaacgtga taaaggagaa ataaaaatgg
    64021 cagaaattta tctagcaggt ggttgttttt ggggcctaga ggaatatttt tcacgcattt
    64081 ctggagtgct agaaaccagt gttggctacg ctaatggtca agtcgaaacg accaattacc
    64141 agttgctcaa ggaaacagac catgcagaaa cggtccaagt gatttacgat gagaaggaag
    64201 tgtcactcag agagatttta ctttattatt tccgagttat cgatccttta tctatcaatc
    64261 aacaagggaa tgaccgtggt cgccaatatc gaactgggat ttattatcag gatgaagcag
    64321 atttgccagc tatctacaca gtggtacaag agcaggaacg catgctgggt cgaaagattg
    64381 cagtagaagt ggagcaatta cgccactaca ttctggctga agactaccac caagattatc
    64441 tcaggaagaa tccttcaggt tactgtcata tcgatgtgac cgatgctgat aagccattga
    64501 ttgatgcagc aaactatgaa aagcctagtc aagaggtgtt gaaggccagt ctatctgaag
    64561 agtcttatcg tgtcacacaa gaagctgcta cagaggctcc atttaccaat gcctatgacc
    64621 aaacctttga agaggggatt tatgtagata ttacgacagg tgagccactc ttttttgcca
    64681 aggataagtt tgcttcaggt tgtggttggc caagttttag ccgtccgatt tccaaagagt
    64741 tgattcatta ttacaaggat ctgagccatg gaatggagcg aattgaagtt cgttctcgtt
    64801 caggcagtgc tcacttgggt catgttttca cagatggacc gcgggagtta ggcggcctcc
    64861 gttactgtat caattctgct tctttacgct ttgtggccaa ggatgagatg gaaaaagcag
    64921 gatatggcta tctattgcct tacttaaaca aataaaacag agagtggggc ttcccacttt
    64981 cttcatttct agaatatgaa tagaagggat ttatgaaata cctattatct tacttcaaac
    65041 cctacatcaa ggaatcaatt ttagccccct tgttcaagct gttagaagct gtttttgagc
    65101 tcttggttcc catggtgatt gctgggattg ttgaccaatc tttacctcag ggagatcaag
    65161 gtcatctctg gatgcagatt ggcctgctcc ttatctttgc agtaattggc gttttagtgg
    65221 ccttgatagc tcaattttac tcagcaaagg cagcagtagg ctttgctaag gaattgacaa
    65281 acgatcttta tcgtcatatt ctttccttgc ccaaggacag cagagaccgt ctgacaactt
    65341 ctagtttggt cactcgcttg acttcggata cctaccagat tcagactggt atcaatcaat
    65401 tcctgcgtct ctttttgcga gcgcccatta tcgtttttgg tgccattttt atggcttatc
    65461 gaatctcagc tgagttgact ttctggttct tagtcatggt tgccattttg accattgtaa
    65521 ttgtagggtt atctcgattg gtcaatcctc tctacagtag tctcagaaag aaaacggacc
    65581 aactggttca ggaaacgcgc cagcaattgc aagggatgcg ggttattcgt gcttttggtc
    65641 aagaaaaacg agagttacag atttttcaaa cccttaacca agtttatgct agattacaag
    65701 aaaagacagg tttctggtct agtttattaa cacctctgac ctatctgatt gtcaatggaa
    65761 ctcttctcgt tattatctgg caaggctata tttcaattca aggaggagtg ctcagtcaag
    65821 gtgctctcat tgctcttatc aattacctct tacagatttt ggtggaattg gtcaagctag
    65881 ccatgttgat caattccctc aaccagtcct atatctcagc caagcgaatc gaggaagtct
    65941 ttgttgaggc tccagaggat atccattcag agttagaaca aaagcaagct accagagata
    66001 aggttttaca agtccaagaa ttgaccttta cctatcctga tgcagcccag ccttctctga
    66061 gagacatttc ctttgatatg actcaaggac aaattctagg tatcatcggg ggaactggtt
    66121 ctggtaaatc aagcttgatt caactcatac ttggacttta tccagtaaac aagggaagaa
    66181 ttgaccttta tctagatgga ttgagtcctc ttaatttgga gcaatggaga tcttggattg
    66241 cctatgtgcc acaaaaggtc gaactcttta agggaactat tcgttccaac ttgactttag
    66301 gtttaaatca agaagtgact gatcaagaac tctggcaagc cttggaaatt gctcaagcta
    66361 aggattttgt cagtgataag gaaggactct tggatgctct agttgaagca ggaggtcgaa
    66421 atttctcagg tggacaaaaa caaaggctgt ctatcgcacg agcagtcttg cgccaggctc
    66481 cgtttctcat cctagatgat gcgacctcgg cactggatac cattaccgag tccaagctct
    66541 tgaaagctat ccgcgaagat ctgccaaata tgagcttaat cttgatttct caacggactt
    66601 cgacactcca gatggcggac cagattctcc tcttggaaaa aggtgagttg ctagctgttg
    66661 gcaagcacga tgacttgatg aaatccagcc aagtctatcg tgaaatcaat gcatcccaac
    66721 atggaaagga ggactagaat gaaacgacaa actgtaaacc agacgctcaa acgtttagcc
    66781 gtagatttag caagccatcc tttcttcctt ttcctagcct ttctaggaac tattgcccaa
    66841 gttggcttat caatttacct acctattctg attgggcagg tcattgacca agtcctagtg
    66901 gctggttcat caccagtttt ttggcagatt tttctccaga tgctcttggt ggtaatagga
    66961 aatactctgg tacaatgggc caatcctctc ctctataatc gtctaatctt ctcttatacc
    67021 agagatttac gggagcgaat catccataag ctccatcgtt taccgattgc ctttgtagat
    67081 aggcaaggta gtggagagat ggttagtcgt gtaaccacgg acatcgaaca gttggcagct
    67141 ggcttgacca tgatttttaa ccaatttttc attggtgttt tgatgatttt ggttagtatt
    67201 ctagccatgc tccaaattca tctcctcatg actctcttag tcttgctgtt gacgccactg
    67261 tccatggtga tttcacgctt tattgccaag agatcctatc atctcttcca gaagcaaaca
    67321 gagacgaggg gaattcagac tcagttgatt gaagaatcgc ttagccagca gactataatc
    67381 cagtccttca atgctcaaac agaatttatc caaagattgc gtgaggctca tgacaactac
    67441 tcaggctatt ctcagtcagc catcttttat tcttcaacgg tcaatccttc gactcgcttt
    67501 gtaaatgcac tcatttatgc ccttttagct ggagtaggag cttatcgtat catgatgggt
    67561 tcaaccttga ccgtcggtcg tttagtgact tttttgaact atgttcagca atacaccaag
    67621 ccctttaatg atatttcttc agtgctagct gagttgcaaa gtgctctggc ttgcgtagag
    67681 cgtatctatg gagtcttaga tagccctgaa gtggctgaaa caggtaagga agtcttgacc
    67741 agtgaccaag ttaagggagc tatttccttt aaacatgtct cttttggcta ccatcctgaa
    67801 aaaattttga ttaaggactt gtctatcgat attccagctg gtagtaaggt agccatcgtt
    67861 ggtccgacag gtgctggaaa atcaactctt atcaatctcc ttatgcgttt ttatcccatt
    67921 agctcgggag atatcttgct ggatgggcaa tccatttatg attatacacg agcatcattg
    67981 agacagcagt ttggcatggt gcttcaagaa acctggctca cacaagggac cattcatgat
    68041 aatattgcct ttggcaatct tgaagccagt cgagagcaag taattgctgc tgccaaagca
    68101 gctaatgcag actttttcat tcaacagttg ccacagggat acgataccaa gttggaaaat
    68161 gctggagaat ctctctctgt cggccaagct cagctcttga ccatagcccg agtctttctg
    68221 gctattccaa agattcttat cttagacgag gcaacttctt ccattgatac acggacagaa
    68281 gtgctggtac aggatgcctt tgcaaaactc atgaagggcc gcacaagctt catcattgct
    68341 caccgtttgt caaccattca ggatgcggat ttaattcttg tcttagtaga tggtgatatt
    68401 gttgaatatg gtaaccatca agaactcatg gatagaaagg gtaagtatta ccaaatgcaa
    68461 aaagctgcgg cttttagttc tgaataagcc attctctttt gaaagtttat ggacgaaaaa
    68521 agttgccttc gagtgacttt tttgttacaa tagctagaaa aattgttcac tgtaatactc
    68581 aatgaaaatc aaagagcaaa ctaggaagct agccgtaggt tgctcaaagc acagctttga
    68641 ggttgtagat aagactgacg aagtc
//
LOCUS       DAVHTH010000004        60179 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.004, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000004 DAVHTH010000000
VERSION     DAVHTH010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 60179)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 60179)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..60179
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.004"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            120..857
                     /locus_tag="VVR63_000251"
     CDS             120..857
                     /locus_tag="VVR63_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU6128315.1"
                     /translation="MTYTILIVEDEYLVRQGLTKLVNVAAYDMEIIGQAENGRQAWEL
                     IQKQVPDIILTDINMPHLNGIQLASLVRETYPQVHLVFLTGYDDFDYALSAVKLGVDD
                     YLLKPFSRQDIEEMLGKIKQKLDKEEKEEQLQDLLTNRFEGNMAQKIQSHLADSQFSL
                     KSLASDLGFSPTYLSSLIKKELGLPFQDYLVRERVKQAKLLLLTTDLKIYEIAEKVGF
                     EDMNYFTQRFKQIAGVTPRQFKKGEDR"
     gene            854..2545
                     /locus_tag="VVR63_000252"
     CDS             854..2545
                     /locus_tag="VVR63_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU6128316.1"
                     /translation="MKRSSLLVRMVISIFLVFLILLALVGTFYYQSSSSAIEATIEGN
                     SQTTISQTSHFIQSYIKKLETTSTGLTQQTDVLAYAENPSQDKVEGIRDLFLTILKSD
                     KDLKTVVLVTKSGQVISTDDSVQMKTSSDMMAEDWYQKAIHQGAMPVLTPARKSDSQW
                     VISVTQELVDAKGANLGVLRLDISYETLEAYLNQLQLGQQGFAFIINENHEFVYHPQH
                     TVYSSSSKMEAMKPYIDTGQGYTPGHKSYVSQEKIAGTDWTVLGVSSLEKLDQVRSQL
                     LWTLLGASVTSLLVCLCLVWFSLKRWIAPLKDLRETMLEIASGAQNLRAKEVGAYELR
                     EVTRQFNAMLDQIDQLMVAIRSQEETTRQYQLQALSSQINPHFLYNTLDTIIWMAEFH
                     DSQRVVQVTKSLATYFRLALNQGKDLICLSDEINHVRQYLFIQKQRYGDKLEYEINEN
                     VAFDNLVLPKLVLQPLVENALYHGIKEKEGQGHIKLSVQKQDSGLVIRIEDDGVGFQD
                     AGDSSQSQLKRGGVGLQNVDQRLKLHFGANYHMKIDSRPQKGTKVEIYINRIETS"
     gene            2661..3224
                     /locus_tag="VVR63_000253"
     CDS             2661..3224
                     /locus_tag="VVR63_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HEU6128317.1"
                     /translation="MNETQIQRETRQVVEDVLEKTNLKQGALFVLGLSSSEVLGGHIG
                     KESSQEIGELIVETILDILGSRGIHLAVQGCEHVNRALVVERQVAEQFGLEIVSVHPT
                     LHAGGSGQLAAFKFMQDPVEVEFIKAHAGLDIGDTAIGMHVKHVQVPIRPILREIGHA
                     HVTALASRPKLIGGARAHYPQDAIRKT"
     gene            3246..8915
                     /locus_tag="VVR63_000254"
     CDS             3246..8915
                     /locus_tag="VVR63_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FIVAR domain-containing protein"
                     /protein_id="HEU6128318.1"
                     /translation="MFKKDRFSIRKIKGVVGSVFLGSLLMAPSVVDAATYHYVNKEII
                     SQEAKDLIQTGKPDRNEVVYGLVYQKDQLPQTGTEASVLTAFGYLSGDILKTLGLDTV
                     LEETSAKPGEVTVVEVETPQSTTNQEQARTENQVVETEEAPKEEAPKTEESPKEEPKS
                     EIKPTDDTLPKVEEGKEDSAEPAPVEEVGGEVESKPEEKVAVKPESQPSDKPTEEPKV
                     EQVGEPVEPSEDEQAPTAPVEPEKQPEAPEEEKAVEETPKPEDKIKGIGTKEPVDKSE
                     LNNQIDKASSVSPTDYSTASYNDLGPVLETAKGVYASEPVKQPEVNSETNKLKTAIDA
                     LNVDKTELNNTIADAKTKVKEHYSDRSWQNLQTGVTEAEKVAANTDAKQSEVNSETAS
                     LKTAISRLNTDKVELENQLKIAQGKTETDFSMESWTVLSTAKNKAQEVKDNGTATQEQ
                     INEAEKSLKTALADLSVDKTALGSAIDTATKKNKENYTNQTWAELETALTAAKSVNTN
                     ESKQSDVNEAAEKLTATMEKLVELSEKPRLTLSIEKRDIDRKATVTYTLENPANTQIK
                     SITATLKKGEEVVKDFVLTEENLKTNHLTALFEKLDYYKEYTLSTDMVYNRGNDDETE
                     SISEELIQLNLKKLELKDIQTVSLMKFENGQESQVTHLSDKPTDLSKLYLKVTSSTSK
                     DAVLAVSSIEEEIIENKKIFKIHADTPELVVRKKDGSLSKGFDYYMERVIPHDGDIYY
                     DFKDLISAMTSNPTGTFILGRDISSRNVKPDGNGKSYIKGEFKGKLLGTNDNVRHSIF
                     DLEYPLFDTIKSGVVKDIDFKHVNMVFPDSNQGDNVATIARVIKDKTKIENVNVEGYL
                     EGRDHVAGLVNNLEGNSEIENVSFTGKIKSKGGNSITAGIAGRNILSRVKRAYVNADI
                     EVHRSSNSSMLVAVNGINADASGGWGTWGRLTESVAKGTLETKQGGQAGGASSTVWPY
                     GAIDNVVSYAKVTKGKELFGSDGDLNYDWFMKKISNIFGVQGISSGDSGSDSKFTRIS
                     EEEANQKVASYNITAPNLMSDSSLLVDRLNESWKNTDQFESIQDYQAQNQLIYQNLTK
                     FTPYYNKEFIVHEGNALTPEQEILKTKKIKSIVGLKGTEFVVDGSDIDTIMLHFEDGS
                     QKRYKVTSTGKFSITNLPEYQVEDLNVVYTSEHIVHPLDSSLINNLVEELKKVELYTE
                     STYQVLGIDKDNANKLNRTKRLFLDESLDAVKTQLPTFVKTMFENEWLHINGESSGAV
                     AALRQKIMDNKTAILLALTYINRYYDVKFSDYNIKKLMLFKPTFHGEKIDLLDRLIRL
                     GSSGENRLKGSENAETFKQLFASETKQKDLVTYLDYNRSLLTNYQTTGEWFKETTKDY
                     IQFEERPSLVEEIKDAKYRVYDNLTAPYYQGYILPLLTLKNTHLAILSNYSTMTFVSR
                     EKRPNWKNEDFDKWVKYVATAHRNHVDTWYKILPDNIKGKMVKENVTAVWEGLSIPGS
                     EWVDQNAVDRKGRDYAPAREFFNLVGGPMGGWYAYHGYGAHAGGRNRVNYEVFDVLSE
                     YGISVFTHELTHVNDTWIYLGGYGRRENMGPEAYAQGLFQSPVPGQPGWGALGLNMAF
                     ERKNDGDLIYNASPTQFENRKELDSYMKNYNDTLMMVDYLEGDAVISKGKEAITKWFK
                     KVEPKVVSQTAQYDTVRQLTAEEKEKLSVSSVDDLVDQGLMSDRAVGNNTYNPADFET
                     SYIAIDYMTGIYGGGKNSVGSPGALMFKHNTFRMWGYYGFEEGVLGYASNKFKQASRD
                     EGHAGLSDNFIISKISKGEFLTMEAFKKGYFKKVVEELKTKGIRPVTINQKTYSTFEE
                     LQEGFKQAVERDLKKNQLDERETRNFKFQVFRQLLQQTDSFKTSIFR"
     gene            8976..10697
                     /gene="pabB"
                     /locus_tag="VVR63_000255"
     CDS             8976..10697
                     /gene="pabB"
                     /locus_tag="VVR63_000255"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000554849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HEU6128319.1"
                     /translation="MHRKTVIDFRTLGERYTFTQPIKELKTRNVEEVADLLAQVESYQ
                     EQGYYVVGYVSYEAAPAFEEKLAVHKDPLLGEYLLYFTVHDSVETSPIPLTYEDIDLP
                     SNWQEVTSAADYEKAIAQIHHHLRQGDTYQVNYTVQLKQKLNANPFAIYNRMVVEQEA
                     GYNAYVEHDEMAVISMSPELFFEQNDRELTTRPMKGTTQRGVTDQEDLEQASWLEQDP
                     KNRSENMMIVDLLRNDMNRISEVGSEHVERLCQVEQYSTVWQMTSTIKSQLREDVDLV
                     EIFHSLFPCGSITGAPKIATMEIIKDLEPQPRGVYCGTIGLLLPNGRRIFNVAIRTIQ
                     LHKGQAIYGVGGGITWDSTWESEYREVHQKAAVLYRKQARFQLITTGKISQKQLMFEE
                     QHLERLRKASRYFAYPFDPEILRQKIEAECQTCDANQDYRLRISLSKSGEIEFSRQIL
                     TPLSPSFCQAKLCLQEANLNQSFTYFKTTYRPHLSIEEQEKIYHNGKGELLETSIGNL
                     VLKIDGKLYTPPIRLGILPGIYHQYLLETGQVEEKVLTLADFAQAEAIYGCNAVRGLY
                     ELQVIGL"
     gene            10817..12343
                     /locus_tag="VVR63_000256"
     CDS             10817..12343
                     /locus_tag="VVR63_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEU6128320.1"
                     /translation="MKSKIVLGASLAIATLSLVSLVEIEGLSPFLIENVSANTHSANK
                     VINHKVSIYLENADEGKGLTVNFSTDSVSPNLFDEFEKKSGITITTMLVNAKTGEVVE
                     KRLTPSVFLRSNDLTSGTISSFIFSEYPDGEYKYVVSKGDFIDPKTQFKHQYRGESPV
                     FRIRNRKYVELGTTDKKLDERRDNSVYKDGVVEHKVNLSLTSYQGGNGVTAIFSTDSV
                     NSNLLNSFGEKAKKVLIRSKLINVKTGEVIDETFSPKVSLTSKILKSGSTAVFYFIDL
                     TDGEYKYVAYESQQYTDPQTTLTHQYRGESPIFSIKDGKFSGLVSASKPDENPKPTPK
                     PDEKPKPSAPQQEKTKPTVQSGWVGSSYYQNGKKVTSKWIFDKKYNSYFYLDASGNYV
                     QNAWVGNYYLKSGGYMAKSEWIYDKNYGSYYYLTSEGSYARNTWSGNYYLKSNGKMAK
                     SEWVYDSNYKSYYYLTSEGSYARNTWVGNYYLKSNGKMAVNERTPDGYRVDGSGKWVK
                     "
     gene            12430..13349
                     /locus_tag="VVR63_000257"
                     /pseudo
     CDS             12430..13349
                     /locus_tag="VVR63_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811638.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
     gene            13484..14443
                     /locus_tag="VVR63_000258"
     CDS             13484..14443
                     /locus_tag="VVR63_000258"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002919069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HEU6128321.1"
                     /translation="MSQKIIGIDLGGTSIKFAILTTAGEIQGKWSIKTNILDEGSHIV
                     DDMIESIQHRLDLLGLAAADFQGIGMGSPGVVDRDKGTVIGAYNLNWKTLQPIKQKIE
                     KALGIPFFIDNDANVAALGERWMGAGDNQPDVVFMTLGTGVGGGIVAEGKLLHGVAGA
                     AGELGHITVDFDQPISCTCGKKGCLETVASATGIVNLTRRYADEYEGDAALKRLIDNG
                     EEVTAKTVFDLAKEGDDLALIVYRNFSRYLGIACANIGSILNPSTIVIGGGVSAAGEF
                     LLQGVQKVYDENSFPQVRTSTKLALATLGNDAGVIGAASLVLQ"
     gene            14540..15379
                     /locus_tag="VVR63_000259"
     CDS             14540..15379
                     /locus_tag="VVR63_000259"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HEU6128322.1"
                     /translation="MTKADTIFKENIECILKEGVFSEQARPKYKDGTVANSKYVTGAF
                     SEYDLSKGEFPITTLRPIAIKSAIKEVLWIYQDQSNSLEVLNDKYNVHYWNDWEVGDT
                     GTIGERYGAVVKKHDIINKLLKQLETNPWNRRNIISLWDYQAFEETDGLLPCAFQTMF
                     DVRRVDGEIYLDATLTQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFINNL
                     HIYDNQFEQAQELLRREPSNCQPRLVLNVPDGTNFFDIKAEDFELVDYDPVKPQLKFD
                     LAI"
     gene            complement(15427..15597)
                     /locus_tag="VVR63_000260"
     CDS             complement(15427..15597)
                     /locus_tag="VVR63_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001051775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HEU6128323.1"
                     /translation="MAKGFAKGLVTGVAGTVAAVAGAVYAFKKKVIEPEEQKAAFIEE
                     NRKKAARRRVSR"
     gene            15718..16602
                     /gene="miaA"
                     /locus_tag="VVR63_000261"
     CDS             15718..16602
                     /gene="miaA"
                     /locus_tag="VVR63_000261"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HEU6128324.1"
                     /translation="MKTKIIVIVGPTAVGKTALAIEVAKRFNGEVVSGDSQQVYRGLD
                     IGTAKASPEEQAAVPHHLIDVREITESYSAFDFVSEAKMTIEDIQSRGKLAIIAGGTG
                     LYIQSLLEGYHLGGETPHEEILAYRASLEPYSDEELAHLVEQAGLEIPQFNRRRAMRA
                     LEIAHFGQDLENQEILYEPLIICLDDERSQLYERINHRVDLMFEAGLLDEAKWLFDHS
                     PNVQAAKGIGYKELFPYFRGEQTFEEARESLKQATRRFAKRQLTWFRNRMQVTFYQIG
                     ESGVQDRILSQIEEFLDD"
     gene            16595..17833
                     /gene="hflX"
                     /locus_tag="VVR63_000262"
     CDS             16595..17833
                     /gene="hflX"
                     /locus_tag="VVR63_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HEU6128325.1"
                     /translation="MIETEKKEERVLLIGVELQGMDSFDLSMEELASLAKTAGAVVVD
                     SYRQKREKYDSKTFVGSGKLEEIALMVDAEEITTVIVNNRLTPRQNVNLEEVLGVKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYLLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSVRNQITDIERQLKVVEKNRATVREKRLESSTFKIGLIGYTNAGKSTIMNIL
                     TSKTQYEADELFATLDATTKSIHLGGNLQVTLTDTVGFIQDLPTELVSSFKSTLEESK
                     HVDLLVHVIDASNPYHEEHEKTVLSIMKDLDMEDIPHLTLYNKADLVEDFTPTQTPYT
                     LISAKSEDSRENLQALLLDKIKEIFEAFTLRVPFSKSYKIHDLESVAILEERDYQEDG
                     EVITGYISEKNKWRLEEFYD"
     gene            17826..18449
                     /locus_tag="VVR63_000263"
     CDS             17826..18449
                     /locus_tag="VVR63_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HEU6128326.1"
                     /translation="MTDIKTLALKYGGYTSLDKVYLDQLLAGKTDQEQLTLITPPPSV
                     VNAYFAELYQKKSPQAATDYFAELSQELNLYNTEPSFTLENKPFIRLNLSGKSFGFCY
                     ESDGLGRIFFENEEKISDDLLFEIAQIFPHQLVFEESGKIYMKPVEDEEVISLESLTA
                     LTDLERLADGRKRLKGYSQEDLLQEAAAFSGKRYFRSENRTAMLYID"
     gene            18464..19393
                     /locus_tag="VVR63_000264"
     CDS             18464..19393
                     /locus_tag="VVR63_000264"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HEU6128327.1"
                     /translation="MDIQFLGTGAGQPSKARNVSSLALKLLDEINEVWLFDCGEGTQN
                     RILETTIRPRKVSKIFITHLHGDHIFGLPGFLSSRAFQANEEQTDLEIYGPQGIKSFV
                     LTSLRVSGSRLPYRIHFHEFDQDSLGKILETDKFTVYAEELDHTIFCVGYRVMQKDLE
                     GTLDAEKLKAAGVPFGPLFGKIKNGQDLVLEDGTEIKAADYISAPRPGKIITILGDTR
                     KTGASVRLAVNADVLVHESTYGKGDEKIARNHGHSTNMQAAQVAVEAGAKRLLLNHIS
                     ARFLSKDISKLKKDAATIFENVHVVKDLEEVEI"
     gene            19414..20169
                     /locus_tag="VVR63_000265"
     CDS             19414..20169
                     /locus_tag="VVR63_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEU6128328.1"
                     /translation="MPTILITGASGGLAQEMVKLLPNDQLILLGRNKEKLAQLYGNYS
                     HAELIEIDITDDSALEALVTDLYLRYGKIDVLINNAGYGIFEGFDQIADKDIHQMFEV
                     NTFALMNLSRHLAARMKESSKGHIINIVSMAGLIATGKSSLYSATKFAAIGFSNALRL
                     ELMPYGVYVTTVNPGPIRTGFFDQADPDGTYLKSVDRFLLEPDAVAKKIVKIIGKNKR
                     ELNLPILLNLAHKFYTLFPKLADKLAGETFNYK"
     gene            complement(20223..21131)
                     /locus_tag="VVR63_000266"
     CDS             complement(20223..21131)
                     /locus_tag="VVR63_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEU6128329.1"
                     /translation="MRIQQLHYIIKIVETGSMNEAAKQLFITQPSLSNAVRDLENEMG
                     IEIFIRNPKGITLTRDGMEFLSYARQVVEQTQLLEERYKNPVAHRELFSVSSQHYAFV
                     VNAFVSLLKKSDMEKYELFLRETRTWEIIDDVKNFRSEVGVLFLNSYNRDVLTKMLDD
                     NHLLAHHLFTAQPHIFVSKTNPLAKKDKVKLSDLENFPYLSYDQGTHNSFYFSEEILS
                     QEHHKKSIVVSDRATLFNLLIGLDGYTIATGILNSNLNGDNIVSIPLDIDDPIELVYI
                     QHEKTSLSKMGERFIDYLLEEVQFDS"
     gene            21195..21464
                     /locus_tag="VVR63_000267"
     CDS             21195..21464
                     /locus_tag="VVR63_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HEU6128330.1"
                     /translation="MSLFLKKTQNFARMSLMKTFYDVQQFLKRFGIIVYMGKRLYDIE
                     LMKLELSRIYDAGLMDKLDYLEAEAVLRREHKVELDYIEKNGEKN"
     gene            21464..21844
                     /locus_tag="VVR63_000268"
     CDS             21464..21844
                     /locus_tag="VVR63_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEU6128331.1"
                     /translation="MVTWILWALILAMLAWMGFNYLRIRRAAKIVDNEEFEALIRTGQ
                     LIDLRDPAEFHRKHILGARNIPSSQLKTSLAALRKDKPVLLYENQRAQRVTNAALYLK
                     KQGFSEIYILSYGLDSWKGKVKTS"
     gene            21933..22160
                     /locus_tag="VVR63_000269"
                     /pseudo
     CDS             21933..22160
                     /locus_tag="VVR63_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660075.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(22200..22925)
                     /locus_tag="VVR63_000270"
     CDS             complement(22200..22925)
                     /locus_tag="VVR63_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA pseudouridine(516) synthase"
                     /protein_id="HEU6128332.1"
                     /translation="MRLDNLLAQEKISRKAMKQALLRGKILVDGCPARSLAQNIDTGL
                     QELLFQDRIIQGYEHTYLMLHKPAGVVTANKDKELPTVMDLLPSDIQSDKLYAVGRLD
                     RDTTGLLLLTDNGPLGFQLLHPQYHVDKTYQVEVNGLLTPDHIQAFQKGIVFLDGTVC
                     KPAKLEILSASPSISQASITISEGKFHQIKKMFLSVGVKVTILKRIQFGDFTLNPDLA
                     ESNYRPLNQKELQIIKNYLEMSR"
     gene            23087..24928
                     /gene="typA"
                     /locus_tag="VVR63_000271"
     CDS             23087..24928
                     /gene="typA"
                     /locus_tag="VVR63_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003078415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HEU6128333.1"
                     /translation="MTKLREDIRNIAIIAHVDHGKTTLVDELLKQSETLDARTELAER
                     AMDSNDIEKERGITILAKNTAVAYNGTRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQDLVPIVVVNKIDKPSARPAEVVDEVLELFIELGADDDQ
                     LDFPVVYASAINGTSSLSDDPADQEATMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAG
                     DLIAVSGMEDIFVGETITPTDAVEALPILHIDEPTLQMTFLVNNSPFAGKEGKWVTSR
                     KVEERLQAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IVKEIDGVKCEPFERVQIDTPEEYQGSVIQSLSERKGEMLDMISTGNGQTRLVFLVPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPLIPGEIGGRHRGALVSIDAGKATTYSIMS
                     IEERGTIFVNPGTEVYEGMIIGENSRENDLTVNITKAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAEREKANKKKKSAE"
     gene            24948..25202
                     /locus_tag="VVR63_000272"
     CDS             24948..25202
                     /locus_tag="VVR63_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HEU6128334.1"
                     /translation="MVYLVLGILLLLLYVFATPESIKGTVNIVAMVCILVALLILLVL
                     SFLKIFQLPTEIFLAIAMLLLAYFSVRDITLMPVKKSKRR"
     gene            25567..25866
                     /locus_tag="VVR63_000273"
                     /pseudo
     CDS             25567..25866
                     /locus_tag="VVR63_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397967.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
     gene            25949..27970
                     /locus_tag="VVR63_000274"
                     /pseudo
     CDS             25949..27970
                     /locus_tag="VVR63_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000732428.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
     gene            27972..28613
                     /locus_tag="VVR63_000275"
     CDS             27972..28613
                     /locus_tag="VVR63_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6128335.1"
                     /translation="MIELKNISKKFGSRQLFSDTNLHFEGGKIYALIGTSGCGKTTLL
                     NMIGRLEPYDKGQIIYDGTSLKDIKPSVFFRDYLGYLFQDFGLIESQTVKENLNLGLV
                     GKKLKEKEKISLMKQALNCVNLSYLDLKQPIFELSGGEAQRVALAKIILKDPPLILAD
                     EPTASLDPKNSEELLSILESLKNPNRTIIIATHNPLIWEQVDQVIRVTDLSHR"
     gene            28717..30069
                     /locus_tag="VVR63_000276"
     CDS             28717..30069
                     /locus_tag="VVR63_000276"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HEU6128336.1"
                     /translation="MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGAIVTVNDGKPFE
                     DNPAAQCLLEEGIKVITGGHPLELLDEEFALMVKNPGIPYSNPMIEKALAKGIPVLTE
                     VELAYLISEAPIIGITGSNGKTTTTTMIGEVLTAAGQHGLLSGNIGYPASQVAQIASD
                     KDTLVMELSSFQLMGVQEFHPEIAVITNLMPTHIDYHGSFSEYVAAKWNIQNKMTAAD
                     FLVLNFNQDLAKDLTSKTEATVVPFSTLEKVDGAYLEDGQLYFRGEVVMAANEIGVPG
                     SHNVENALATIAVAKLRDVDNQTIKETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNI
                     LATQKALSGFDNSKVVLIAGGLDRGNEFDELVPDITGLKKMVILGQSAERVKRAADKA
                     GVAYVEATDIADATRKAYELATQGDVVLLSPANASWDMYANFEVRGDLFIDTVAELKE
                     "
     gene            30073..31131
                     /locus_tag="VVR63_000277"
     CDS             30073..31131
                     /locus_tag="VVR63_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HEU6128337.1"
                     /translation="MKKIVFTGGGTVGHVTLNLLLMPKFIEDGWEVHYIGDKRGIEHQ
                     EILKSGLDVTFHSIATGKLRRYFSWQNMLDVFKVGWGIVQSLFIMLRLRPQILFSKGG
                     FVSVPPVIAARVSGVPVFIHESDLSMGLANKIAYKFATKMYSTFEQASSLSKVEHVGA
                     VTKVSDQKNPEPDELVDIQTHFNHKLPTVLFVGGSAGARVFNQLVTDHKKELTERYNI
                     INLTGDSSLNELSQNLFRVDYVTDLYQPLLELADIVVTRGGANTIFELLAIAKLHVIV
                     PLGREASRGDQIENAAYFVKKGYAEDLQESDLTLDSLEEKLSHLLSHKEDYQAKMKAS
                     KELKSLADFYQLLKKDLS"
     gene            31141..32340
                     /gene="divIB"
                     /locus_tag="VVR63_000278"
     CDS             31141..32340
                     /gene="divIB"
                     /locus_tag="VVR63_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIB"
                     /protein_id="HEU6128338.1"
                     /translation="MSKDKKNEDKEILEELKELSEWQKRNQEYLKKKAEEEAALAEEK
                     EKERQARMGEESEKSEDKQDQESETDQEDSESAKEESEEKVASSEDDKEKEEKEEPES
                     KEKEEQDKKLAKKATKEKPAKAKIPGIHILRAFTILFPSLLLLIVSAYLLSPYATMKD
                     IRVEGTVQTTADDIRQASGIQDSDYTINLLLDKAKYEKQIKSNYWVESAQLVYQFPTK
                     FTIKVKEYDIVAYYISGENHYPILSSGQLETSSVSLNSLPETYLSVLFNDSEQIKVFV
                     SELAQISPELKAAIQKVELAPSKVTSDLIRLTMNDLDEVLVPLSEMSKKLPYYSKIKP
                     QLSEPSVIDMEAGIYSYTVADKLIMEAEEKAKQEAKEAEKKQEEEQKKQEEESNRNQT
                     TQRSSRR"
     gene            32573..33274
                     /gene="pyrF"
                     /locus_tag="VVR63_000279"
     CDS             32573..33274
                     /gene="pyrF"
                     /locus_tag="VVR63_000279"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HEU6128339.1"
                     /translation="MREHRPVIALDFPSFEAVKEFLALFPAEESLYLKVGMELYYAAG
                     PEIVSYLKGLGHSVFLDLKLHDIPNTVKSAMKVLSQLGVDMTNVHAAGGVEMMKAARE
                     GLGSQAKLIAVTQLTSTSEAQMQEFQNIQTSLQESVIHYAKKTAEAGLDGVVCSAQEV
                     QVIKQATNPDFICLTPGIRPAGAAVGDQKRVMTPADAYQIGSDYIVVGRPITQAEDPV
                     AAYHTIKDEWTQDWN"
     gene            33308..33940
                     /locus_tag="VVR63_000280"
     CDS             33308..33940
                     /locus_tag="VVR63_000280"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HEU6128340.1"
                     /translation="MTLAKDIASHLLKIQAVYLKPEEPFTWASGIKSPIYTDNRVTLA
                     YPETRTLIENGFVEAIKEAFPEVEVIAGTATAGIPHGAIIADKMDLPFAYIRSKPKDH
                     GAGNQIEGRVAQGQKMVVVEDLISTGGSVLEAVAAAKREGADVLGVVAIFSYQLPKAD
                     KNFADAGVKLVTLSNYSELIHLAQEEGYITPEGLDLLKRFKEDQENWQEG"
     gene            34120..34523
                     /locus_tag="VVR63_000281"
                     /pseudo
     CDS             34120..34523
                     /locus_tag="VVR63_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000829085.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            34619..35383
                     /locus_tag="VVR63_000282"
     CDS             34619..35383
                     /locus_tag="VVR63_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6128341.1"
                     /translation="MEFFICNLVRVVQSPRFYMSLFLTLLCMSLGNFLAFNGIYKIEG
                     LSIFFAASSIRGFSPISLVAALICTLPYSSQIIEDAESHFLTAQLCRISKKKYLAIVG
                     STVIISSFLVFFLPYLLLLGINLLVTPYQEIYIGDYSGALKELFDSNQFLYSLVTTLW
                     YGVWGAVFSIFGLASALLVKKKIGAIFIPVAYMMVGGIFWAILGLSYLEPVTTLALGY
                     QKDISLSLVSGHLAFILFVSCLVVYGTFFLHSEDYV"
     gene            35383..36135
                     /locus_tag="VVR63_000283"
     CDS             35383..36135
                     /locus_tag="VVR63_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6128342.1"
                     /translation="MKQFVQFYKKDFLSVLVYFILLLSCVLSSTVYLLRCRQYSIHPN
                     VLEWILVLLQDMTTGVYCFPFTYILFFFYLMNNYFNRLECRIRLKSIKHFTSFSFKLA
                     ALSTGIWTATLFLLIFLIAFSNGFSFSLEIKEVDFLREFYGISIANNASFFIGFFFSY
                     IAYYFFLSLLTISSFSWFKKSNMSLVFLFTFLFVESLFWIYQLDNGIIGLLPIFQYMV
                     NSNPYALIYWLTLLSIIIPLTVFSVHRNWRRV"
     gene            36145..36843
                     /locus_tag="VVR63_000284"
     CDS             36145..36843
                     /locus_tag="VVR63_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6128343.1"
                     /translation="MGKLSSHMWRLNQIIYTKYFWGYVLFWILICLGLWYWLEGNDRL
                     VIEILKGPNLSQNSFLVLSIWLLHWFIIHTFFLAVVYRRRASDFFMEVIRFSSIKLWI
                     RYQIWTCFLYGLILIMVKVLVIQFMLQLPNWDIGVLFIVDSLNACVLVLFCFMLYALG
                     ANVQMNFACVSFFLLMIVFGGLFVGNRTNYLFYILNRGNGDIGRDLFLQLLFLVFLFK
                     SIFYFTRQKRRFIE"
     gene            36840..37487
                     /locus_tag="VVR63_000285"
     CDS             36840..37487
                     /locus_tag="VVR63_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6128344.1"
                     /translation="MNEIIILKNIELKLKKTCVFQNLNFSCKQGEIIGITGANGSGKS
                     VLFKLIAGLYSPSYGEVLINGENIVPERKIPANLGALIEEPGFINYYSGFKNLQYLAS
                     IRGVVGNQEINDTLKIVGLYEQKDQKVKTYSLGMRKKLGIAQAIMENPSILLLDEPMN
                     ALDKSSVENMRTLFRKLSSEKGTTILIASHSEEDIRILCDKVYAIEDKVCTLCSD"
     gene            complement(37567..38428)
                     /locus_tag="VVR63_000286"
                     /pseudo
     CDS             complement(37567..38428)
                     /locus_tag="VVR63_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765255.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine ABC transporter substrate-binding
                     protein"
     gene            complement(38440..39198)
                     /locus_tag="VVR63_000287"
     CDS             complement(38440..39198)
                     /locus_tag="VVR63_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU6128345.1"
                     /translation="MSETILEIKELKKSFGDNPILQGLSLEIKKGEVVVILGPSGCGK
                     STLLRCLNGLESIQGGDIFLDGQSIVENKKNFHLVRQKIGMVFQSYELFPHLDVLQNL
                     ILGPIKTQGRDKKEVTEEALQLLDRVGLLDKQHSFARQLSGGQKQRVAIVRALLMHPE
                     IILFDEVTASLDPEMVREVLELINDLAQEGRTMILVTHEMQFAQAIADRIIFLDQGKI
                     AEEGTAQAFFTNPQTKRAQEFLNVFDFSQFGSYL"
     gene            complement(39199..39876)
                     /locus_tag="VVR63_000288"
     CDS             complement(39199..39876)
                     /locus_tag="VVR63_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001154125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU6128346.1"
                     /translation="MQDSGIQVLFQGNNLLRILQGLGVTIGISILSVLLSMMFGTVMG
                     IIMTSHSRIIRFLTRLYLEFIRIMPQLVLLFIVYFGLARNFNINISGETSAIIVFTLW
                     GTAEMGDLVRGAITSLPKHQFESGQALGLTNVQLYYHIIIPQVLRRLLPQAINLVTRM
                     IKTTSLVVLIGVVEVTKVGQQIIDSNRLTIPTASFWIYGTILVLYFAVCYPISKLSTH
                     LEKHWRN"
     gene            complement(39836..40504)
                     /locus_tag="VVR63_000289"
     CDS             complement(39836..40504)
                     /locus_tag="VVR63_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006531263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU6128347.1"
                     /translation="MVEQYLPLYQKAFFLTLHIAVWGILGSFLLGLIVSIIRHYRILV
                     LSQVATAYIELSRNTPLLIQLFFLYFGLPRIGIVLSSEVCATLGLVFLGDSYMAESFR
                     SGLEAISQTQQEIGLAIGLTPLQVFYYVVLPQATAVALPSFSANVIFLIKETSVFSAV
                     ALADLMYVAKDLIGLYYETDIALAMLVVAYLIMLLPISLVFSWIERRLRHAGFGNPST
                     LSRK"
     gene            40730..40876
                     /locus_tag="VVR63_000290"
     CDS             40730..40876
                     /locus_tag="VVR63_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
                     /protein_id="HEU6128348.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAGDTF
                     TSFQ"
     gene            41004..42494
                     /gene="lysS"
                     /locus_tag="VVR63_000291"
     CDS             41004..42494
                     /gene="lysS"
                     /locus_tag="VVR63_000291"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HEU6128349.1"
                     /translation="MSTEHMEELNDQQIVRREKMAALREQGIDPFGKRFERTANSQEL
                     KDKYTNLDKEQLHDKNETATIAGRLVTKRGKGKVGFAHLQDREGQIQIYVRKDAVGEE
                     NYEIFKKADLGDFLGVEGEVMRTDMGELSIKATHITHLSKALRPLPEKFHGLTDVETI
                     YRKRYLDLISNRESFERFVTRSKIISEIRRYLDQKGFLEVETPVLHNEAGGAAARPFI
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADFQDIMDLTEGIIQHAAKSVKGDGPVNYQGTEIKINEPFKRVHMVDAIREITGVD
                     FWQDMTLEEAKAIAAEKKVPVEKHYTEVGHIINAFFEEFVEETLIQPTFVYGHPVAVS
                     PLAKKNPEDQRFTDRFELFIMTKEYGNAFTELNDPIDQLSRFEAQAKAKELGDDEATG
                     IDYDYIEALEYGMPPTGGLGIGIDRLCMLLTDTTTIRDVLLFPTMK"
     gene            43120..44256
                     /gene="lctO"
                     /locus_tag="VVR63_000292"
     CDS             43120..44256
                     /gene="lctO"
                     /locus_tag="VVR63_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate oxidase"
                     /protein_id="HEU6128350.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TLRENIRAFNHKLIVPHTLCDVENPSTEIEFAGEKLSSPIIMAPVAAHKLANEQGEVA
                     TARGVHEFGSLYTTSSYSTVDLPEISEALQGTPHWFQFYFSKDDGINRHIMDRVKAEG
                     YKAIVLTADATVGGNREVDKRNGFVFPVGMPIVEEYLPEGAGKSMDFVYKSAKQRLSP
                     RDVEFIAEYSGLPVYVKGPQCREDVERSLAAGASGIWVTNHGGRQIDGGPAAFDSLQE
                     VAEAVDKRVPIVFDSGVRRGQHVFKALASGADLVAIGRPVIYGLALGGSVGVRQVFEH
                     LNAELKTVMQLSGTQTIEDVKHFKLRHNPYNPTFPVDPRDLKLY"
     regulatory      44510..44598
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            44813..45481
                     /locus_tag="VVR63_000293"
     CDS             44813..45481
                     /locus_tag="VVR63_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000449895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TenA family protein"
                     /protein_id="HEU6128351.1"
                     /translation="METQDYAFQPGLTVGELLKSSQKDWQAAINHRFVKELFAGTIEN
                     KVLKDYLIQDYHFFDAFLSMLGACVAHADKLESKLRFAKQLGFLEADEDGYFQKAFKE
                     LKVAENDYLEVTLHPVTKAFQDLMYWAVASSDYAHLLVMLVIAEGLYLDWGSKDLALP
                     EVYIHSEWINLHRGPFFAEWVQFLVDELNRVGKNREDLTELQQRWNQAVALELAFFDI
                     GYDV"
     gene            complement(45631..45723)
                     /locus_tag="VVR63_000294"
                     /pseudo
     CDS             complement(45631..45723)
                     /locus_tag="VVR63_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            45807..46589
                     /gene="thiM"
                     /locus_tag="VVR63_000295"
     CDS             45807..46589
                     /gene="thiM"
                     /locus_tag="VVR63_000295"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HEU6128352.1"
                     /translation="MTSLKLLKEKAPLVICITNDVVKNFTANGLVALGASPAMSEFPA
                     DLEDLLKYAGGLLINIGTLTDENWKLYQAALKIAEKYNVPVVLDPVACGAGEYRKKVA
                     DDLINNYKLAAIRGNAGEIASLVGIDVASKGVDSAGVDNIDEIALAANEKFNIPIVVT
                     GEVDAIAVNGEVVTIHNGSAMMPKVIGTGCLLGAVVASFIGLEKGQELKSLETAMLVY
                     NIAGEMAEKRPNGHLPGTFKVEFINALYEITDEDVKEFKRVK"
     gene            46591..47220
                     /locus_tag="VVR63_000296"
     CDS             46591..47220
                     /locus_tag="VVR63_000296"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000468574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HEU6128353.1"
                     /translation="MFHKELLKLYFICGTTTCQGKNLYTVVEEALRGGITLFQFREKG
                     EGALEGLEKLELAIQIKELCKKYNVPFIVNDDIDLAMEIDADGVHVGQDDIGVDEIRK
                     LMPDKIIGLSIKNEEEFQQSKVEYVDYVGVGPVFDTQSKDDAGGAIGYEGVKLMRKLL
                     PQMPLVAIGGIQTKHIKDIMKTNVDGVSIISAISYAKNIEKTVREMSEQ"
     regulatory      47429..47517
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            47779..48339
                     /locus_tag="VVR63_000297"
     CDS             47779..48339
                     /locus_tag="VVR63_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEU6128354.1"
                     /translation="MLKKWQLKDVILLAFLSIFFGGVFVGSGYVYNILSLLLTPLGLQ
                     AFANEILFGLWCMAAPIAAIFVPRVGSATIGEVLAALAEVLYGSQFGLGALLSGLVQG
                     LGSEFGFIVTKNRYESWLSLTANSIGITLVSFVYEYIKLGYYAFSLPFVLSLLVVRFI
                     SVYFFCTILVRAIVKLYHQFATGGKA"
     gene            48340..49725
                     /locus_tag="VVR63_000298"
     CDS             48340..49725
                     /locus_tag="VVR63_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6128355.1"
                     /translation="MGLELRAIQSPIFSEPFDFTFHAQAFTLLVGSSGSGKSSLFQVI
                     AQVSSLPYSGQVLIDGSEVSQLSIVERVQTVGILLQNPNHQFTMESLFEELVFTMENI
                     GYHLQEIDSKIAEVVQQCRCKDILHRLIHHLSGGEKQKAALAVLFAMNPRVYLLDEPF
                     ASIDRKSRIEILEILKELALDGKTVILCDHDLSDYKAYIDYMVELRDGKLREVFQIPS
                     YEMTQVASKEVAASPELFHMNRVTGELGNRPLFSIADFTFYQGISCILGDNGVGKSTL
                     FRSILQFQKYKGRIAWKGTVLKKKKSLYRDLTGVVQEAEKQFIRVSLREELQLDGPDS
                     ERNQRIFQALRYFDLEQAVDKSPYQLSGGQQKILQLLTILTSKASVILLDEPFAGLDD
                     RACHYFCKWIVEERNQGRSFLLISHRLDPLISVVDYWIEMTSQGLRHVKEVTITKPLT
                     SQSSNTQGEVR"
     gene            49727..50377
                     /locus_tag="VVR63_000299"
     CDS             49727..50377
                     /locus_tag="VVR63_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ABC transporter permease"
                     /protein_id="HEU6128356.1"
                     /translation="MVKVATQTPIISLFLLILSLETSFIPSIALNLSVVAFCILFMFY
                     YRRFKMLAWMIILAILPSFANYWAVQLHGDASQAVMLGTRAFVTVCIGLVFVSSISLK
                     ELLLYLAQKGLSRSWSYALIVVFNSFPLIQQEIKSLKEACLLRGQELHFWSPLIYSKV
                     LMTVFRWRHLYLRALSAHGYDEHAQLKNSYRTFYIPKKTKLIYLLFFLLLQTSLFL"
     gene            50388..51080
                     /gene="tenA"
                     /locus_tag="VVR63_000300"
     CDS             50388..51080
                     /gene="tenA"
                     /locus_tag="VVR63_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiaminase II"
                     /protein_id="HEU6128357.1"
                     /translation="MEFTDIAMELSKKAWQASFHHPFILQLQEGNLEPAIFRYYLIQD
                     AYYLKVFSEIYHLLADKTSNQEMKRLLKQNAQGLVEGELFIRQQFFKELEINDQEMEQ
                     HPIAPTCYHYISHIYRQFAEPNLAIAFASLLPCPWLYHDIGKSLNLKPSPNPLYQQWI
                     ETYITDELEQQIREEGALVNQLYRESDETDKQKMLDAFHISVHMEAKFWEMAYQHQTW
                     KSDLQSLEKGEE"
     gene            51085..51609
                     /gene="thiW"
                     /locus_tag="VVR63_000301"
     CDS             51085..51609
                     /gene="thiW"
                     /locus_tag="VVR63_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001225563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy coupling factor transporter S component
                     ThiW"
                     /protein_id="HEU6128358.1"
                     /translation="MRKHQLQVHKLTILSMMIALDVVLTPIFRIEGMAPMSSVVNILA
                     GIMMGPVYALAMATVTAFIRMTTQGIPPLALTGATFGALLAGLFYKYGRKFYFSALGE
                     IVGTGIIGSIVSYPVMVLFTGSAAKLSWFIYTPRFFGATLIGTAISFIAFRFLIKQEF
                     FKKVQGYFFAERIE"
     gene            51609..52412
                     /locus_tag="VVR63_000302"
     CDS             51609..52412
                     /locus_tag="VVR63_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HEU6128359.1"
                     /translation="MQALTNPFPIGSSSLIHCMTNEISCEMLANGILALGCKPVMADD
                     PREVLDFTKQSQALFINLGHLSAEKEKAIRMAALYANQSSLPMVVDAVGVTTSSIRKS
                     LVKDLLDYRPTVLKGNMSEIRSLVGLKHHGVGVDASAKDQETEDLLQVLKDWCQTYPG
                     MSFLVTGPKDLIVSENQVAVLENGCAELDWITGTGDLVGALTAVFLSQGKTGFEASCL
                     AVSYLNIAAEKIVVQGMGLEEFRYQVLNQLSLLRRDENWLDTIKGEVYE"
     gene            52405..53037
                     /locus_tag="VVR63_000303"
     CDS             52405..53037
                     /locus_tag="VVR63_000303"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HEU6128360.1"
                     /translation="MNREALRLYLVTNRYQDSVESFLAKVETACRSGVTIVQLREKNL
                     TTNQYYQLAKQVKEITDAYQVPLIIDDRLDVCLAVDAAGLHIGDDELPVSVARKVLGP
                     EKILGVTAKTVKRALEAEKSGADYLGTGAIFPTTTKENAPITLISTLKTICQTVAIPV
                     VAIGGLTSENIDQLMDTGIAGVAVVRDLMQAEDIEAKTQAFLTKLHDILS"
     gene            complement(53247..54038)
                     /gene="thiD"
                     /locus_tag="VVR63_000304"
     CDS             complement(53247..54038)
                     /gene="thiD"
                     /locus_tag="VVR63_000304"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEU6128361.1"
                     /translation="MTYLPVALTIAGTDPSGGAGIMADLKSFQARDVYGMAVVTSLVA
                     QNTRGVQLIEHVSPQMLKAQLESVFSDIPPQAVKTGMLATTEIMEIIHPYLKKLDCPY
                     VLDPVMVATSGDALIDSSARDYLKTNLLPLATIITPNLPEAEEIVGFSIHDPEDMQRA
                     GRLILKEFGPQSVVIKGGHLKGGAKDFLFTKNEQFVWESPRIQTCHTHGTGCTFAAVI
                     TAELAKGKSLYQAVDKAKAFITKAIQDAPQLGHGSGPVNHTTFKD"
     regulatory      complement(54122..54220)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            54404..54799
                     /locus_tag="VVR63_000305"
     CDS             54404..54799
                     /locus_tag="VVR63_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HEU6128362.1"
                     /translation="MQISDAEWQVMKIIWMQGEQTSTDLIRVLAERFDWSKSTVQTLL
                     ARLVEKECLTRKKEGKSFVYSALLTLDQSRDLLVQDIKDKVCSRRIRNLLADLIVECE
                     FTQTDLEDLEAVISEKKSSAVTEVRCNCM"
     gene            54810..55181
                     /locus_tag="VVR63_000306"
     CDS             54810..55181
                     /locus_tag="VVR63_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupredoxin domain-containing protein"
                     /protein_id="HEU6128363.1"
                     /translation="MLNSIVTIICIALIAFILFWFFKKPEKSGQKAQQKNGYQEIRVE
                     VMGGYTPELIVLKKSVPARIVFDRKDPSPCLDQIVFPDFGVHANLPMGEEYVVEITPE
                     QAGEFGFACGMNMMHGKMIVE"
     gene            55191..57434
                     /locus_tag="VVR63_000307"
     CDS             55191..57434
                     /locus_tag="VVR63_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEU6128364.1"
                     /translation="MTEIVKASLENGIQKIRIRAEKGYHPAHIQLQKGIPAEITFHRA
                     TPSNCYKEILFEEEGILEPIGVDEEKVIRFTPQELGRHEFSCGMKMQKGSYTVVEKTR
                     KSLSLLQRFWITSIFTVPLVILMIGMLAGSISHQVMHWGTFLATTPIMLVAGKPYIQS
                     AWASFKKHNANMDTLVALGTLVAYFYSLVALFAGLPVYFESAGFILFFVLLGAVFEEK
                     MRKNTSQAVEKLLDLQAKTAEVLSDDSYVQVPLEQVKVGDLIRVRPGEKIAVDGVVVE
                     GVSSIDESMVTGESLPVDKTVGDTVIGSTINHSGTLVFRAEKVGSETVLAQIVDFVKK
                     AQTSRAPIQDLTDKISGIFVPVVVILGIMTFWVWFVLLRDSVVVLGASFVSSLLYGVA
                     VLIIACPCALGLATPTALMVGTGRSAKMGVLLKNGTVLQEIQKVQTLVFDKTGTLTEG
                     KPVVTDIIGDEVEVFGLAASLEDASQHPLAEAIVKRASEAGLEFQTVENFQALHGKGV
                     SGRINGKQVLLGNAKMLDGMDISNTYQDKLEELEKEAKTVVFLAVDNEIKGLLALQDI
                     PKENAKLAISQLKKRGLRTVMLTGDNAGVARAIADQIGIEEVIAGVLPEEKAHEIHKL
                     QQSGKVAFVGDGINDAPALSVADVGIAMGAGTDIAIESADLVLTTNNLLGVVRAFDMS
                     KKTFHRILLNLFWAFIYNVVGIPIAAGVFSGVGLALNPELAGLAMAFSSVSVLTSSLL
                     LNFSKID"
     gene            57641..59416
                     /gene="spxB"
                     /locus_tag="VVR63_000308"
     CDS             57641..59416
                     /gene="spxB"
                     /locus_tag="VVR63_000308"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HEU6128365.1"
                     /translation="MTQGKITASAAMLNVLKTWGVDTIYGIPSGTLSSLMDALAEDKD
                     IRFLQVRHEETGALAAVMQAKFGGSIGVAVGSGGPGATHLINGVYDAAMDNTPFLAIL
                     GSRPVNELNMDAFQELNQNPMYNGIAVYNKRVAYAEQLPKVIDEACRAAISKKGPAVV
                     EIPVNFGFQEIDENSYYGSGSYERSFIAPALNEVEIDKAVEILNNAERPVIYAGFGGV
                     KAGEVITELSRKIKAPIITTGKNFEAFEWNYEGLTGSAYRVGWKPANEVVFEADTVLF
                     LGSNFPFAEVYEAFKNTEKFIQVDIDPYKLGKRHALDASILGDAGQAAKAILDKVNPV
                     ESTPWWRANVKNNQNWRDYMNKLEGKTEGELQLYQVYNAINKHADQDAIYSIDVGNTT
                     QTSTRHLHMTPKNMWRTSPLFATMGIALPGGIAAKKDNPDRQVWNIMGDGAFNMCYPD
                     VITNVQYDLPVINLVFSNAEYGFIKNKYEDTNKHLFGVDFTNADYAKIAEAQGAVGFT
                     VDRIEDIDAVVAEAVKLNKEGKTVVIDARITQHRPLPVEVLELDPKLHSEEAIKAFKE
                     KYEAEELVPFRLFLEEEGLQSRAIK"
     gene            59527..59874
                     /locus_tag="VVR63_000309"
     CDS             59527..59874
                     /locus_tag="VVR63_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEU6128366.1"
                     /translation="MNLNQLDIIVSNVPQVCADLEHILDKKADYADDGFAQFTIGSHC
                     LMLSQNHLVPLENFQSGIIIHIEVEDVDQNYKRLNELGIKVLHGPTVTDWGTESLLVQ
                     GPAGLVLDFYRMK"
     gene            complement(59991..>60179)
                     /locus_tag="VVR63_000310"
     CDS             complement(59991..>60179)
                     /locus_tag="VVR63_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HEU6128367.1"
                     /translation="HTRDEPIEQVWKEIRKRGFKNKAFRTLEDVMNQLQDVIQGLEKE
                     VIKSIVNRRWTRMLFESI"
BASE COUNT        18367 a        10723 c        13223 g        17866 t
ORIGIN      
        1 aacctgtggc tatcttccta gtttactttt tgatttttat tgagtataag aggtctttcc
       61 taagcagtta gaggagaatt ttgctatact gatactagta agtggtaaag gagcagagca
      121 tgacctacac aatcttaatc gtagaagatg aatatctggt aagacaaggt ttgactaaac
      181 tggtcaatgt agcagcctac gatatggaaa tcatcggtca ggctgaaaat ggaaggcagg
      241 cttgggaatt gatccaaaag caggtgccag atatcatttt aaccgatatc aacatgcctc
      301 atctaaatgg catccagttg gccagtctgg tacgagaaac ctatcctcag gttcatttgg
      361 tctttttaac aggttacgat gattttgatt atgccttgtc tgctgtcaaa ctaggtgtgg
      421 acgactacct gctcaaaccc ttttctcgtc aggatattga ggaaatgttg gggaaaatca
      481 aacaaaaact agacaaggaa gagaaagaag agcagttaca agatttattg actaataggt
      541 ttgaaggaaa catggcccag aaaatccagt ctcatctggc tgatagccaa tttagtttaa
      601 agtctttagc cagtgactta ggttttagtc cgacctatct gagttccttg attaagaaag
      661 agttgggctt gccttttcag gattatctgg tgagagaacg tgttaaacaa gccaagctct
      721 tgcttttaac tacagatctg aagatttatg agatcgcaga gaaggttggt tttgaagata
      781 tgaactattt tacccaacgt tttaagcaga ttgcaggtgt gacacctcgt cagtttaaga
      841 agggagaaga ccgatgaagc gttcttctct tttagttaga atggttattt ccatctttct
      901 ggtctttctc attctcctag ctctggttgg aactttctac tatcaatcaa gttcttcagc
      961 cattgaggcc accattgagg gcaacagcca aacgaccatc agccagacta gccactttat
     1021 tcagtcttat atcaaaaaac tagaaaccac ctcgactggt ttgacccagc agacggatgt
     1081 tctggcctat gctgagaatc ccagtcaaga caaggtcgag ggaatccgag atttgttttt
     1141 gaccatcttg aagtcagata aggacttgaa aactgttgtg ctggtgacca aatctggtca
     1201 ggtcatttct acagatgaca gtgtgcagat gaaaacttcc tctgatatga tggctgagga
     1261 ttggtaccaa aaggccattc atcagggagc tatgcctgtt ttgactccag ctcgtaaatc
     1321 agatagtcag tgggtcattt ctgtcactca agaacttgtt gatgcaaagg gagccaatct
     1381 tggtgtgctt cgtttggata tttcttatga aactctggaa gcctatctca atcaactcca
     1441 gttggggcag cagggctttg ccttcattat caatgaaaac catgaatttg tctaccatcc
     1501 tcaacacaca gtttatagtt cgtctagcaa aatggaggct atgaaaccct acatcgatac
     1561 aggtcagggt tatactcctg gtcacaaatc ctacgtcagt caagagaaga ttgcaggaac
     1621 tgattggacg gtgcttggcg tgtcatcatt ggaaaagtta gaccaggttc ggagtcagct
     1681 cttgtggacc ttgcttgggg ccagtgtcac atctcttctt gtctgtctct gcttagtgtg
     1741 gttcagtctt aaacgctgga ttgctccttt gaaggatttg agagaaacca tgttggaaat
     1801 tgcttctggt gctcaaaatc ttcgtgccaa ggaagttggt gcctatgaac tgagagaagt
     1861 aactcgccaa tttaatgcta tgttggatca gattgatcag ttgatggtag ctattcgtag
     1921 ccaggaagaa acgacccgtc agtaccaact tcaagccctt tcgagccaga ttaatccaca
     1981 tttcctctat aacactttgg acaccatcat ctggatggct gaatttcatg atagtcagcg
     2041 agtggtgcag gtgaccaagt ccttggcaac ctatttccgc ttggcgctca atcaaggcaa
     2101 ggacttgatt tgtctctctg acgaaatcaa tcatgtccgc cagtatctct ttatccagaa
     2161 acaacgctat ggagataagc tggaatacga aattaatgaa aatgttgcct ttgataattt
     2221 agtcttaccc aagctggtcc tacaacccct tgtagaaaat gctctttacc atggcattaa
     2281 ggaaaaggaa ggtcagggcc atattaaact ttctgtccag aaacaggatt cgggattggt
     2341 catccgtatt gaggatgatg gcgttggctt ccaagatgct ggtgatagta gtcaaagtca
     2401 actcaaacgt gggggagttg gtcttcaaaa tgtcgatcaa cggctcaaac ttcattttgg
     2461 agccaattac catatgaaga ttgattctag accccaaaaa gggacgaaag ttgaaatata
     2521 tataaataga atagaaacta gctaactccc agtcaattct gggagtttta tgcgtaattg
     2581 ggcaaacttt ctaggttgtc tatcttgcta aaaacaagaa aaaacggtat gatagaagag
     2641 tgacaacaga ggtaacagag atgaacgaga cacagattca aagagaaaca cgtcaggtag
     2701 tggaagatgt tttagaaaag accaatttga agcagggggc cctttttgtt ttaggtctat
     2761 cttctagtga ggtgctaggt ggtcatattg ggaaagaatc cagtcaagag attggtgagc
     2821 tgatagtgga gactatcttg gatattctag gtagtagagg tatccattta gcagttcaag
     2881 gttgtgagca tgtcaatcgg gctctcgttg ttgaacgtca ggtggcagag cagtttggtc
     2941 tggaaattgt cagtgtccat cctactcttc atgcaggagg ttcggggcag ttggcagcct
     3001 ttaagtttat gcaggatcca gttgaggttg aatttatcaa ggctcatgct ggattggata
     3061 tcggagacac tgcaattggc atgcatgtca agcatgttca ggttccgatt cgccctattt
     3121 tgagagagat tggtcatgcc catgtaacgg cactggctag tcgtccaaaa ttaatcggag
     3181 gtgcgcgtgc gcactatccg caagatgcta ttagaaagac ctgagaatga ataaaggaga
     3241 taaaagtgtt taaaaaagac cgtttttcaa ttcgtaagat taagggagtt gtaggctctg
     3301 tatttcttgg aagccttttg atggctcctt ctgtagtgga cgcagccacc tatcactatg
     3361 taaataaaga gattatttca caagaagcta aagatttaat tcagacagga aagcctgaca
     3421 ggaatgaagt tgtatatggt ttggtgtatc aaaaagatca gttgcctcaa acagggacag
     3481 aagcatctgt tttgacagct tttggttatc tatcaggtga catcctcaaa acgcttggct
     3541 tggacactgt tttagaagaa acctcagcaa aacctggaga ggtgactgta gtcgaagttg
     3601 agactcctca atcaacaaca aatcaggagc aagctaggac agaaaaccaa gtagtagaga
     3661 cagaggaagc tccaaaagaa gaagcaccta aaacagaaga aagtccaaag gaagaaccaa
     3721 aatcggagat aaaacctact gacgacaccc ttcctaaagt agaagagggg aaagaagatt
     3781 cagcagaacc agctccagtt gaagaagtag gtggagaagt tgagtcaaaa ccagaggaaa
     3841 aagtagcagt taagccagaa agtcaaccat cagacaaacc aacagaggaa ccaaaagttg
     3901 aacaagtagg tgaaccagtc gagccaagtg aagacgaaca ggcaccaacg gcaccagttg
     3961 agccagaaaa gcaaccagaa gctcctgaag aagagaaggc tgtagaggaa acaccgaaac
     4021 cagaagataa aataaagggt attggtacta aagaaccagt tgataaaagt gagttaaata
     4081 atcaaattga taaagctagt tcagtttctc ctactgatta ttctacagca agttacaatg
     4141 atcttggacc tgttttagaa actgcaaaag gtgtctatgc ttcagagcct gtaaaacagc
     4201 ctgaggtaaa tagtgagaca aataaactta aaacggctat tgacgctcta aacgttgata
     4261 aaactgaatt aaacaatacg attgcagatg caaaaacaaa ggtaaaagaa cattacagtg
     4321 atagaagttg gcaaaacctc caaactgggg ttacagaagc tgaaaaagtt gcagctaata
     4381 cagatgctaa acaaagtgaa gtaaattctg agactgcaag tcttaaaaca gcaatttcta
     4441 gattaaatac agataaagtt gaactcgaaa atcaacttaa gattgcacag ggaaaaactg
     4501 aaactgattt cagcatggaa tcttggactg ttttgagtac agctaaaaat aaagctcagg
     4561 aagtaaaaga taacggaaca gcgacccaag aacaaataaa cgaagcagag aaaagtttga
     4621 aaacagccct tgctgactta tctgttgaca aaacagcttt gggaagcgct atcgatacag
     4681 ctactaagaa aaataaagag aattatacaa atcaaacatg ggcagagttg gaaacagcgc
     4741 ttacagcagc aaaatctgta aatactaacg agtctaaaca aagcgacgtt aacgaagctg
     4801 ctgaaaaatt aactgcaact atggaaaaat tggttgaatt gtctgaaaag ccacgtttga
     4861 ctctatctat tgaaaagaga gacatagatc gaaaagctac ggtcacgtat actttggaaa
     4921 atccagcaaa tactcaaata aaatcaataa ctgcaactct gaaaaaagga gaggaagttg
     4981 ttaaggattt tgttttaaca gaagaaaatc ttaaaactaa tcatttaact gctttgtttg
     5041 aaaagctaga ctactacaaa gaatacactc tatctacgga tatggtatat aacagaggaa
     5101 atgatgatga gacggagagt atttcagaag aactaattca gctgaatctt aagaaactag
     5161 aattgaaaga tatccagaca gtctctctga tgaaatttga aaatggtcaa gaaagtcagg
     5221 ttacacactt gtctgataaa ccgaccgatt tgagtaaatt atacttaaaa gttacatcat
     5281 caacgtctaa ggatgctgtg ttagccgtta gctctataga agaagagatt attgaaaata
     5341 aaaaaatctt taaaattcat gcagatacac cagaattagt agttcgtaag aaagatggca
     5401 gtctttctaa gggatttgac tattacatgg agagagttat ccctcatgat ggtgatattt
     5461 attatgattt taaagacttg atttcagcta tgacatctaa tcctacaggt acgtttattt
     5521 tagggagaga tatttcctcg cgtaatgtaa aaccggatgg aaatggaaaa tcttatatca
     5581 aaggtgaatt taaaggaaaa ctacttggta caaatgataa tgttagacac tcgatttttg
     5641 acttagaata tccattgttt gatactataa aatcaggagt cgtgaaagat attgatttca
     5701 agcatgtcaa tatggtattc ccagatagca atcaaggaga taacgtagca acaattgcaa
     5761 gagtaatcaa agataagaca aaaattgaga atgttaatgt tgaaggttat ctcgagggtc
     5821 gagatcatgt agctggttta gttaataatc ttgaaggtaa ttccgaaatt gaaaatgtat
     5881 cctttacagg aaagattaag tctaaaggtg gtaattctat tacagcaggt attgcaggta
     5941 gaaatatctt atctcgtgtt aaacgtgcct atgtaaatgc agatatagag gtacatcgat
     6001 catctaattc tagcatgctt gttgcagtaa atggaataaa tgcagatgca agtggtggtt
     6061 ggggaacctg gggtagactt actgagtcag ttgctaaagg aacattagaa accaagcaag
     6121 gagggcaagc tggaggagcc tcttctacag tctggcctta tggagcaatt gataatgttg
     6181 tcagctatgc aaaagtgacc aaagggaaag aattatttgg atcagatggt gatttaaatt
     6241 atgattggtt tatgaaaaaa attagtaata tttttggtgt tcaaggcatc agctcaggcg
     6301 attcgggtag tgattctaaa tttacgcgta tttctgagga agaagcaaat caaaaagttg
     6361 cttcttataa tattacagct cccaacttga tgagtgactc aagtcttttg gtagacagac
     6421 tcaatgaaag ttggaaaaat actgatcaat ttgaaagtat acaggattat caagcccaaa
     6481 accaattaat ttaccagaac ttgactaaat ttactcctta ttacaataaa gaatttattg
     6541 ttcatgaagg aaatgctctc actcctgaac aggaaatatt gaagactaag aaaatcaaat
     6601 cgattgtagg gttgaaagga acagagttcg ttgtagatgg cagtgatatt gatactatca
     6661 tgcttcattt tgaggatggt agtcagaagc gatataaggt aacctctact ggtaagtttt
     6721 cgataactaa tttaccggaa tatcaggttg aagatttaaa tgtggtgtat acatcagaac
     6781 atatagtaca tccactagat tcgtcactga taaataacct tgttgaagaa ttgaaaaaag
     6841 tagaattgta tacagagtct acttaccaag ttctaggtat tgataaagat aatgctaaca
     6901 aattgaatag aactaagaga ttattcttag atgagtcatt agatgctgtt aaaacacaat
     6961 tgcctacctt tgtaaaaaca atgtttgaaa atgagtggtt gcacatcaat ggagaatcta
     7021 gtggagctgt cgctgcttta cgacaaaaaa tcatggataa taagacggct atattgcttg
     7081 ctttgactta tatcaatcgt tattatgatg ttaaattctc agactataat attaaaaaac
     7141 tgatgctctt taaaccaact ttccatggtg aaaagattga tctattagat cgattaatcc
     7201 gactaggatc atctggagaa aatagattaa aaggttcaga aaatgcagaa acgttcaagc
     7261 agttatttgc tagcgaaacg aagcagaagg atttggtgac ttatttagac tacaatcgct
     7321 ctttgttgac taattatcaa acaacagggg aatggtttaa agaaacgact aaggattata
     7381 ttcaatttga ggaacgtcca tccttagtag aggagattaa agatgccaaa tatcgagttt
     7441 acgataattt aaccgcaccg tattatcaag gatatatcct acctctctta acgttgaaga
     7501 atactcattt agcaatttta tcgaactata gtactatgac atttgtcagc cgtgaaaaac
     7561 gccctaattg gaaaaatgaa gattttgata agtgggtgaa atatgtagca actgctcata
     7621 gaaaccatgt tgatacttgg tataagattt tacctgataa tatcaaaggt aaaatggtta
     7681 aagagaatgt tactgctgtt tgggaaggat tgagcatccc aggaagtgaa tgggtagacc
     7741 agaatgctgt agatagaaaa ggaagagatt acgccccagc tcgagaattc tttaatcttg
     7801 taggtggtcc tatgggaggt tggtatgctt accatggtta tggtgcgcat gctggaggaa
     7861 gaaatcgggt taattatgag gtgtttgatg tattaagtga gtatggtata tcggtcttta
     7921 ctcatgaatt gactcacgtt aatgatactt ggatttactt aggagggtat ggtagacgtg
     7981 aaaatatggg acctgaagct tatgctcagg gattattcca gtctcctgtt ccaggtcagc
     8041 cgggttgggg ggcgcttggt ctcaatatgg catttgaaag aaaaaatgat ggtgatctaa
     8101 tttataatgc ctccccaact caatttgaaa ataggaaaga gttagatagt tatatgaaaa
     8161 attataacga tactctcatg atggtggact acttggaagg agatgcagtt atctctaaag
     8221 gtaaagaagc tattactaaa tggtttaaaa aagttgaacc taaggttgtt agtcaaacag
     8281 ctcagtatga tacggttcgt cagttgactg ctgaagagaa agaaaaactt tctgtttcta
     8341 gtgttgatga tttagttgat caaggattaa tgtcagacag agctgtagga aataatacct
     8401 ataatccagc tgattttgaa acaagttata ttgcgataga ttatatgact ggtatttatg
     8461 gtggaggaaa gaatagtgta ggttcaccag gtgccttgat gtttaaacat aatactttcc
     8521 gtatgtgggg ctactatggt tttgaagaag gtgttctagg atatgcttct aataaattta
     8581 agcaagcatc tagagatgaa ggtcatgctg gacttagtga taactttatt atttctaaga
     8641 tttccaaagg ggaattttta actatggaag catttaaaaa gggatatttt aagaaagtag
     8701 tagaagagtt aaaaactaaa ggtattcgtc ctgttactat caatcaaaaa acatatagca
     8761 cctttgaaga attgcaagaa ggatttaagc aggctgttga aagagatttg aagaaaaatc
     8821 agttagatga gagggaaaca agaaacttca aattccaagt tttcagacaa cttcttcaac
     8881 aaacagatag ctttaaaact tctatcttta gataatcgaa atctctcatc tgctttgcgg
     8941 atgagggttt tcttatttta tgctatactt aaagtatgca tagaaaaaca gtgattgatt
     9001 ttaggacttt gggggagaga tataccttta cccagcctat taaagagttg aaaacgagaa
     9061 atgtagaaga agtggcagat ttgctggcac aagtggaaag ctaccaagag caaggttatt
     9121 atgtggtggg gtatgtcagc tacgaggctg cacctgcttt tgaggaaaaa ttagcagttc
     9181 acaaggatcc cctactggga gagtacctgc tttattttac tgttcatgat agcgtagaaa
     9241 cttcccctat tcctctgact tatgaggata ttgatttgcc ctcaaattgg caggaagtaa
     9301 cgtctgcagc agactatgaa aaggccattg cccaaattca ccatcattta cggcagggag
     9361 atacctatca ggtcaactac accgtccaac ttaagcaaaa gttaaatgcc aatccttttg
     9421 ccatctacaa tcgtatggtg gtagagcagg aggcgggcta caatgcctat gtggaacatg
     9481 acgagatggc agtgatttcc atgagcccag agctcttttt tgagcaaaat gatcgcgagt
     9541 tgacaacacg accaatgaag gggacgactc agcgtggggt aactgaccaa gaagatcttg
     9601 aacaggccag ttggttggaa caggatccca aaaatcgctc tgaaaatatg atgattgtgg
     9661 acctcttgcg caatgatatg aaccgtattt ctgaagttgg gagcgagcac gtggagcgtc
     9721 tgtgtcaggt agagcagtat tcaactgttt ggcagatgac ttcgaccatc aagagtcagt
     9781 tgcgagagga tgtggacctt gttgaaatct tccactcact ctttccttgt ggttccataa
     9841 cgggtgcacc gaaaattgcg acaatggaga ttatcaagga cttggagcct caaccgcgtg
     9901 gagtctactg tggaacgatt ggtctcttgc ttccaaatgg acgacggatt tttaatgtgg
     9961 ccattcgtac cattcaactt cacaaaggtc aagccattta tggagttggc ggagggatta
    10021 cttgggatag cacttgggaa tctgaatacc gtgaagttca tcaaaaggca gcagttctct
    10081 atcgtaaaca agctcgcttc caattaatta caactggaaa aatcagccaa aaacaactga
    10141 tgtttgaaga acaacatctg gaaaggctga gaaaagctag tcggtatttt gcttatcctt
    10201 ttgacccaga aattttgaga caaaagattg aagcagagtg tcagacttgt gatgctaatc
    10261 aagattaccg cttgcgaatt tctctcagca agtctggaga gatagaattc agtcgtcaaa
    10321 tcttaacacc tcttagtcca agtttttgtc aggccaaact ttgtctgcaa gaagcgaatt
    10381 tgaatcaatc ctttacctat tttaaaacga cttacagacc gcatttgagc atagaggaac
    10441 aagagaagat ttaccataat ggaaaaggag aacttcttga aacctctatc ggaaatttgg
    10501 ttctgaaaat cgatgggaaa ctctacacac cgcctatccg acttggaatc ttgccaggaa
    10561 tttatcacca gtatttacta gaaacaggac aggtagaaga gaaagtcttg accttggcag
    10621 attttgccca agcagaagct atttacggct gtaatgcagt gagaggcttg tatgagttgc
    10681 aagtgatagg attgtgagtt ttagctatta atagttttta atatatatta aaatatattg
    10741 gtgtttactt ttgatgagat atcatatttg tgttataatg taaccgtaaa caatagaaat
    10801 ttaaaggaga tttttgatga aatcaaaaat agttttggga gcttcgctag cgatcgcaac
    10861 acttagctta gtatctcttg tcgagattga aggactctca ccgtttttaa tagagaatgt
    10921 tagcgcaaat actcattctg caaataaagt tattaatcat aaagtaagta tttacttaga
    10981 aaatgctgat gaaggtaaag gtctaactgt aaacttttca acagacagtg ttagtccaaa
    11041 tttatttgat gagttcgaaa aaaagagtgg aattacaata actactatgt tagtgaatgc
    11101 taagacaggt gaagttgtag aaaaaagatt aacaccaagc gtttttttac gttccaatga
    11161 tttaaccagt gggaccatat cttcgtttat ttttagtgaa tatcctgatg gagaatataa
    11221 atatgttgtg tctaaaggag actttatcga tcctaagact cagtttaaac atcagtatag
    11281 aggagaatct ccagttttta gaatacgtaa tcgaaaatat gtggagttgg gaacaactga
    11341 taaaaaatta gatgaaagac gtgataatag cgtttataaa gatggggttg ttgaacacaa
    11401 ggtaaattta agtttaacaa gttatcaagg aggtaatgga gttactgcaa ttttttcaac
    11461 tgatagtgtt aactctaact tacttaattc ttttggtgaa aaggctaaaa aagttttgat
    11521 taggtctaag ttaattaatg ttaagactgg cgaggttatt gatgaaacgt tttctccaaa
    11581 agtaagttta acctctaaaa ttttgaaaag tggttctaca gcagtatttt attttataga
    11641 tttaactgat ggcgaatata aatatgttgc gtatgaaagc cagcaatata ctgatcctca
    11701 aacaacattg actcatcagt atagaggaga atctcctatt tttagtatca aagatggaaa
    11761 attttctggt ttagtatctg cctcaaaacc agacgaaaac ccgaagccaa cgccaaaacc
    11821 ggatgagaaa ccaaaacctt cagcaccaca acaggagaaa acaaaaccta cagttcagtc
    11881 tggttgggta ggttcatctt attatcaaaa tggtaaaaaa gtcactagta agtggatttt
    11941 tgataaaaaa tataattcat acttctatct agatgcatca ggaaattatg ttcaaaacgc
    12001 ttgggtaggt aactattatc tcaaatcagg cggatacatg gctaaaagtg agtggattta
    12061 tgataagaac tatggttcat actactatct aacatcagaa ggcagctacg ctcgtaacac
    12121 ttggtcaggc aattattatt tgaagtcaaa tggtaagatg gctaaaagtg agtgggtata
    12181 cgatagtaac tacaaatcat attactactt gacatcagaa ggaagttatg ctcgtaacac
    12241 ttgggtaggc aattactatc ttaaatcaaa cggtaaaatg gctgttaatg aacgtacacc
    12301 agatggttat cgtgtagatg gttcaggtaa atgggttaaa taagaaacta aaaaatagga
    12361 taataggtaa tatcagatga ataaaaaaaa ttattttcat gtgctttagc attttcaacg
    12421 attggaacat tgtcaacgat tgataaatca ggagttcttc ctttttcagc gcaaacggtg
    12481 caggctgaca tacaaacgct taccccaatg gcaaaatatt atattattct tccgaaggat
    12541 gcagaaatat ataaaacttg gagaggtact gtcaatattc ccattattga tgctacaaaa
    12601 actactccag aattatctta tttcaaagaa gatcatcgca actatatagc taatgagaat
    12661 aagtctggtg ccaattacat agagtggaag ggaacagtag aagagtttaa agaggccatt
    12721 aagaagttga ctgataaaaa atcaactact gcaacaccaa aaaaggatga aaagccaaca
    12781 ccaaaaccgg atgagaagcc aaaaccaaca cctacagttc agtctggttg ggtaggttca
    12841 tcctattatc aagatggtaa aaaagtcatt agtaagtgga tttttgataa aaaatataat
    12901 tcatacttct atctagatgc atcaggaaat tatgttcaaa acgcttgggt aggtaactat
    12961 tatcttaaat caggcggata catggctaaa ggtgaatggg tttatgatgc cacctatcaa
    13021 gcttggtatt atttgacatc agatggttct tatgcttaca gtacatggca aggaaattac
    13081 tatctaaaat cggatggtaa aatggctgtc aatgaatggg ttgatggtgg acgttattat
    13141 gttggcgctg acggagtttg gaaggaaggt caagcaagta cagcttcttc tagtaatgat
    13201 agcaatagtg aatattctgc tgctttagga aaggcaaaaa gttataattc gttattccac
    13261 atgtcaaaaa aaaacgtatg tatagacaat taacttctga ttttgataaa ttttcaaatg
    13321 atgcagctca atatgccatt gatcattaga tgattaacag atactggtag gcgaaaaaat
    13381 tccttataat tcatttacgc aaacctttgc ataagtgaat ggattttgat atactagtac
    13441 tgtaagcatt ttcaattact acacaatgaa aaaggagaat atgatgagtc aaaagattat
    13501 tgggattgac cttggtggaa cttctatcaa atttgcaatc ttaacaacag caggagaaat
    13561 ccaaggaaaa tggtcaatca agaccaacat tttggatgag ggaagtcata tcgttgatga
    13621 tatgattgag tctattcaac atcgtttgga cttgcttgga ttggcagcag cggacttcca
    13681 aggcattgga atgggatcac caggtgtggt tgaccgtgac aaagggactg ttatcggtgc
    13741 ctacaacttg aactggaaaa cccttcaacc aatcaaacaa aagattgaaa aagctttggg
    13801 cattccattt ttcatcgata atgatgccaa cgtagcagct cttggtgagc gctggatggg
    13861 tgctggagat aaccaaccag acgttgtctt tatgacactc ggtactggtg ttggtggcgg
    13921 tatcgtcgca gaaggcaaat tgcttcacgg tgttgctggt gcagcaggtg agcttggtca
    13981 catcactgtt gactttgacc agccaatctc atgtacttgc ggtaagaaag gctgccttga
    14041 gacagttgct tcagcaacag ggattgtcaa cttgactcgt cgctatgccg atgaatacga
    14101 aggcgatgca gccttgaaac gcttgattga taatggagaa gaagtaactg ctaagactgt
    14161 ctttgatctc gcaaaagaag gagacgacct tgctttgatt gtttaccgta acttctcacg
    14221 ttacttggga atcgcttgtg ctaacattgg ttcaatccta aacccatcaa caatcgtcat
    14281 cggtggtggt gtgtcagctg cgggagaatt ccttctacaa ggtgttcaaa aagtttacga
    14341 tgaaaatagt ttcccacaag tacgcacatc tactaaatta gctcttgcaa ctctaggaaa
    14401 tgacgctgga gttatcggag cagcatcact tgtattgcaa taagataatg agagaggaaa
    14461 atgctaacct agagttagta atgttcctct tttatttttt atgctatact agttaggaca
    14521 atgaatgagg tgagagtaaa tgacaaaagc agatacgatt tttaaagaga atattgaatg
    14581 cattctaaag gaaggtgttt tctcagagca agctcgtcct aagtacaagg atgggactgt
    14641 tgctaattcc aagtatgtaa ctggtgcctt ttccgagtac gacttatcta aaggagaatt
    14701 tcctatcaca accttgcgtc ccattgcaat caaatccgcc atcaaagaag ttctctggat
    14761 ttaccaagac cagtcaaata gcttagaagt gcttaatgac aagtacaatg ttcactactg
    14821 gaatgactgg gaagttggag acacgggaac cattggtgag cgctatggtg ccgttgttaa
    14881 gaaacacgac attatcaata agcttctcaa acagttggaa accaatcctt ggaatcgccg
    14941 caatattatt tcgctctggg attaccaagc tttcgaagaa acagatgggc tgctcccgtg
    15001 cgcctttcag accatgtttg atgtccggcg tgttgatggg gaaatctatc tggatgcgac
    15061 cttgacccag cgctccaatg atatgctggt ggcccaccac atcaacgcta tgcagtatgt
    15121 ggctttacag atgatgattg ccaaacattt tggttggaag gttgggaagt tcttctattt
    15181 catcaacaac ctccatatct atgataatca atttgaacaa gctcaggaat tgctccgtcg
    15241 ggagccgtca aactgccaac cacgcttggt tttaaatgtt cctgatggga ctaatttctt
    15301 tgatatcaaa gcagaagatt ttgagttggt ggattatgac cctgttaagc cacagttgaa
    15361 gtttgaccta gctatttaaa agaatagaaa aaagaagttg agaataatcc caacttcttt
    15421 tgtttcttaa cgtgatacgc ggcgacgagc tgctttttta cgattttctt cgatgaaagc
    15481 tgctttttgc tcttctggtt cgattacttt ctttttaaat gcgtatactg cacctgcaac
    15541 ggcagcgaca gttcctgcga cacctgttac aagaccttta gcgaatcctt tagccatgag
    15601 tcttcctcct ttatattctc aatcagccag cctcctcaag aggtcacatt tttctgactg
    15661 acctttttgt gttataataa tagtaacgaa aaaatgggaa tttttcaagg aaaaaagatg
    15721 aaaacaaaaa taattgtgat tgttggaccg actgctgttg gaaagacggc tctagctatt
    15781 gaagttgcaa agcgctttaa tggcgaagtg gttagtggag atagccagca agtctatcga
    15841 ggacttgata ttgggacggc caaggctagt ccagaagagc aggcagctgt tcctcatcat
    15901 ttaatcgatg ttagagagat aaccgagtct tactcggctt ttgattttgt ttcagaagct
    15961 aagatgacta ttgaggatat tcagagccgt ggcaagctag ccattatcgc cggtgggact
    16021 ggactttata tccagagctt gctagaaggt taccacctag gtggggagac tcctcatgag
    16081 gagattttag cttatcgagc tagtttggag ccatattcag atgaggaatt agcccatttg
    16141 gtggagcaag caggccttga gattccccag tttaatcgtc gtcgtgctat gcgtgcctta
    16201 gaaattgccc attttggtca ggatttggaa aatcaagaga tcttgtatga accgctgatt
    16261 atctgcttgg atgatgaacg tagtcaactt tatgagcgta tcaaccaccg agtggatttg
    16321 atgtttgagg ctgggctttt ggatgaggcc aagtggctgt ttgaccattc ccctaatgta
    16381 caggctgcta aaggaattgg ctataaggaa ctctttcctt atttccgtgg agagcagacc
    16441 tttgaggaag ctcgtgagag tcttaaacag gcgacccgtc gttttgccaa gcgtcagctg
    16501 acctggttcc gtaatcgcat gcaggtcacc ttttatcaga ttggagaatc tggtgtacaa
    16561 gaccgcattt taagccagat agaggagttt ttagatgatt gaaacggaga aaaaagagga
    16621 gcgagtcctg ctgattggtg tggaattgca gggtatggac agttttgacc tctccatgga
    16681 agaattggct agtttagcga aaacggcagg ggcagtcgtt gtagatagct acagacaaaa
    16741 acgtgaaaaa tatgattcca agaccttcgt cggctctggt aagttggaag agattgcgct
    16801 tatggtggat gcagaagaaa tcactactgt catcgtcaac aatcgtctga ccccaaggca
    16861 gaatgtcaat ctagaggaag ttctcggtgt taaggtcatt gaccgtatgc agttgatttt
    16921 ggatatcttt gccatgcggg ctcgaagcca tgaagggaag ctccaagtcc acctagccca
    16981 actcaaatac ctcttgcctc gcttggttgg tcaggggatt atgctcagcc gtcaggcagg
    17041 gggaattggt tcccgtggtc ctggtgaaag ccaactggag ctgaaccgtc gtagcgttcg
    17101 caatcaaatc acggatatcg agcgccagct taaggtggtt gagaaaaatc gtgcgactgt
    17161 cagagaaaaa cgtttggagt ctagcacttt taagattggt ttgattggtt atactaatgc
    17221 tgggaaatca actatcatga acatcttgac cagtaagacc cagtatgaag cagatgagct
    17281 ctttgcgact ctggatgcga caaccaagag tattcatctg ggaggcaatc tccaagtaac
    17341 tttgacagat accgttggct ttatccaaga tttgccgaca gagttggtgt ccagtttcaa
    17401 gtcaaccttg gaagaaagca agcatgtgga ccttctggtt catgttatcg atgctagcaa
    17461 tccttaccac gaggagcatg aaaaaacggt tctctccatc atgaaagacc tggacatgga
    17521 agatattcct cacttgacgc tttataataa agcggatttg gtggaggatt tcacgcctac
    17581 ccaaacgcca tataccctca tttctgccaa gtctgaggac agtcgtgaaa acttgcaagc
    17641 attattgcta gataagatta aggaaatttt tgaagcattt accctgcgag tgcctttttc
    17701 aaagtcctac aagattcatg atttagagag tgttgcaatt ctggaagaac gtgattatca
    17761 ggaagacggc gaagtgatta caggctacat ttccgagaaa aataaatgga ggttagaaga
    17821 attttatgac tgatattaaa actttggctc taaagtatgg aggttataca agtctggaca
    17881 aggtctatct ggatcagctt ctagctggta aaacagatca ggagcagtta acacttatta
    17941 cacctccgcc aagtgttgtt aatgcctact ttgcagaact ctatcagaaa aagagtcctc
    18001 aggctgcgac ggattatttt gcagaactca gtcaggaact gaatctttac aatactgagc
    18061 caagtttcac cctagaaaat aagcctttta ttcggcttaa tctgtctggt aaatcctttg
    18121 gtttttgtta tgagagtgac ggccttggtc ggattttctt tgaaaatgag gagaaaatct
    18181 cggatgactt gctctttgaa attgcgcaaa ttttccccca tcaattagtc tttgaagagt
    18241 ctggtaagat ttacatgaag cctgtcgagg acgaggaagt tatcagccta gaaagtctca
    18301 cagctttgac tgatttggaa agattggctg atggtcgaaa acgtctcaaa ggctacagcc
    18361 aagaggattt attgcaagaa gctgctgctt tttctggcaa acgctatttc cgatcggaaa
    18421 accgcacagc catgttatat attgattaat tagaaagtat cgaatggata ttcaattttt
    18481 aggaacgggg gctggtcagc cctctaaagc ccgcaacgtt tcaagtctcg ccctgaaact
    18541 tttggatgag attaacgaag tttggctctt tgactgtgga gaaggtacgc aaaatcgcat
    18601 tctggaaacc acaattcgac cacgtaaggt cagcaaaatc tttattaccc atctgcatgg
    18661 agaccacatt tttggtttgc caggtttcct ttctagccgt gcctttcagg ccaatgaaga
    18721 gcagacagat ttggaaatct acggacctca aggaatcaag tcatttgtct taaccagcct
    18781 tcgtgtgtca ggttctcgtc tgccctaccg cattcatttc catgagtttg accaagattc
    18841 tctgggtaaa attcttgaaa ccgataaatt cactgtgtat gcagaggagc tggaccacac
    18901 tattttctgt gttggctatc gtgtcatgca aaaggatcta gaagggacgc tggatgctga
    18961 aaaactcaag gctgctggtg ttccgttcgg cccgcttttt ggtaaaatca aaaacggcca
    19021 ggatcttgtt ttggaagacg gaactgaaat caaggcagca gactatatct cagcgccacg
    19081 tccaggtaag attatcacta ttttaggaga cactcgaaaa acgggtgcca gtgtgcgtct
    19141 ggctgtcaat gcagatgtcc tagttcatga gtccacttat ggcaagggtg atgaaaaaat
    19201 tgctcgtaac catggtcact caactaatat gcaagctgca caagtagcgg tagaagcagg
    19261 tgccaaacgc ctcctactca accatatcag tgcccgtttc ctctcaaaag atattagcaa
    19321 actcaagaaa gacgctgcca caatttttga aaatgtccat gtggtcaaag acttggaaga
    19381 agtggaaatc tagcagtcac agaaaggata agtatgccta ctattctcat taccggagct
    19441 agcggtggtc tagctcaaga aatggtcaaa ctcctgccca atgaccaact catcttgctt
    19501 ggtagaaata aggaaaaatt agcccaactc tacggaaatt attcccatgc agaattgatt
    19561 gaaattgata ttaccgacga ttcagcccta gaagctctgg taactgatct ttatctccgc
    19621 tatggcaaga ttgatgtctt gattaacaac gctggttacg ggatttttga gggatttgac
    19681 cagattgctg ataaagatat tcaccagatg tttgaggtca atacctttgc cctgatgaat
    19741 ctgtctcgtc accttgcggc tcgtatgaag gaaagcagca aaggtcatat catcaacatc
    19801 gtcagcatgg caggtctaat agctactggc aagtctagtc tttactcagc gaccaagttt
    19861 gcggctattg gtttttcaaa tgctctgcga ctcgaactta tgccctatgg agtctatgtg
    19921 acaacagtca atccaggtcc aatccgaaca ggatttttcg accaagccga cccagatgga
    19981 acttatctta aatcggttga ccgcttcctg ctagaaccag atgcagtggc taaaaagatt
    20041 gtcaagatta taggaaaaaa caaacgagaa ctcaatctcc cgattttgtt gaacctagct
    20101 cataagtttt ataccctctt tcctaagcta gctgataagt tggcagggga aacttttaat
    20161 tataagtaaa aagaaccaat gtgcaggttg ttgctagcct acatattggt tcttatcatt
    20221 tctcaactat caaactgaac ttcttctagg agatagtcta taaagcgttc gcccatctta
    20281 gataggctgg ttttctcatg ctggatatag accagctcga tcgggtcatc aatatccagt
    20341 gggatagaaa cgatattgtc tccgtttagg ttgctgttca aaatccctgt cgcaatggta
    20401 taaccatcca aaccaatcaa gagattaaag agggtggcac ggtcactgac cacaatggat
    20461 ttcttgtggt gttcttgaga aagaatctct tctgaaaagt agaaggagtt gtgcgtccct
    20521 tggtcatagc tgaggtaagg gaaattctcc aaatcagaca gtttcacctt gtctttcttt
    20581 gccagagggt tggtcttgct gacaaagata tgtggttgcg ctgtgaagag atggtgggct
    20641 agcaggtgat tgtcatccag catcttggtt aaaacatcac ggttgtaact gtttaagaag
    20701 aggaccccga cctcactgcg gaagttcttg acgtcgtcga taatctccca agtccgagtt
    20761 tcacgaagga agagttcgta tttctccata tcgcttttct tgagcaaaga gacaaaggca
    20821 ttgaccacaa aggcatagtg ttgagacgaa acgctaaata gttcgcggtg ggcgacagga
    20881 tttttatagc gttcctccag aagctgggtc tgctcgacaa cctgacgggc ataagagaga
    20941 aactccatcc catcacgggt caaggtgatt cccttgggat tgcggataaa gatctcaatg
    21001 cccatttcat tttccaaatc tcgcactgca ttggagagac ttggctgagt gataaagagt
    21061 tgcttggctg cctcattcat ggagccagtt tcgacgattt tgataatata atgtaattgt
    21121 tgaattctca tgtttttatt gtaccatact tgccttagaa tcgctaaaga agataggaaa
    21181 ataaggagca ttgtgtgagt ctcttcttga aaaaaacaca aaattttgct agaatgagtc
    21241 ttatgaaaac attctatgat gtgcagcaat tcctcaaacg atttggtatt attgtttaca
    21301 tgggaaaacg cttatatgat attgaactga tgaagttgga actatctcgg atttacgatg
    21361 cagggttgat ggataaatta gactatctag aggcagaagc agttcttcgc agagagcaca
    21421 aggtagaatt ggattatatt gagaaaaatg gagaaaagaa ctaatggtta cttggatttt
    21481 gtgggcactt atactagcaa tgttggcgtg gatgggcttt aactatcttc gtattcgccg
    21541 tgcggctaaa attgtggaca atgaggagtt tgaagccttg attcgtacgg gtcaattgat
    21601 tgatttgcgc gacccagcag aattccacag aaaacatatc cttggtgcac gcaatattcc
    21661 ttcaagtcag ttgaaaacta gtcttgcagc ccttcgtaaa gataaacctg tccttctcta
    21721 cgagaaccaa cgtgcgcaac gagttacaaa tgcagctctt tacttgaaaa aacaaggttt
    21781 ttctgagatt tatatccttt cttatggctt ggattcttgg aaagggaaag tgaagactag
    21841 ctaaccttat ttccaaatta gtcgaatgat aggatgaagc tattgtttta tagtataatt
    21901 aatttgtata aaatttaagg agttcttaga acataaaaga aaagaagaaa aatccacttt
    21961 ttgtgggtat cttgtcgatt attcttggtt tgttatttcc aattgtaggc ctgattttgg
    22021 gtatcatagg attggtcttg gctatttcat accaaaaaga gtcataatta gactataaaa
    22081 tagaaaagat tcttaatatc ttaggaattg tgatttctgt agttaactgg attgtagcaa
    22141 tcgccttaat ttttcggtaa ataaaagaaa aaagctttag ttttaaagct ttttttgttt
    22201 tatcgactca tctctaaata gtttttaatg atttgtaact ctttttggtt caaagggcgg
    22261 tagttacttt ctgctaaatc tgggttcaat gtgaagtccc caaattggat tctcttgagg
    22321 atagtcacct taacaccaac cgagaggaac attttcttga tttgatgaaa ttttccttct
    22381 gaaatggtga tagaggcttg actgatggag ggacttgcag atagaatctc tagttttgcg
    22441 ggtttacaga cagtaccatc taaaaagaca attccctttt gaaaggcttg gatatggtca
    22501 ggtgttagaa gtccattaac ctcaacttga taagtcttat cgacatgata ttggggatgg
    22561 aggagttgga agcccaaggg accgttatcg gtcaagagga ggagtcccgt tgtatctcgg
    22621 tccagtcggc caacggcata gagcttgtca gactggatgt cagatggaag caggtccatg
    22681 acggtcggaa gttccttgtc tttgttggct gtaacgacac cagcaggttt atgaagcata
    22741 agataggtgt gttcatagcc ttgaatgatt cgatcctgaa aaaggagttc ttgtagtcct
    22801 gtatcgatat tttgagctag ggagcgggct gggcaaccat cgactagaat tttccctctg
    22861 aggagtgctt gcttcatggc ctttcggctg attttttctt gggctaataa attatctaaa
    22921 cgcatactgt gcctatctta tcataagtcg cttgctttga aaaggcttga cgtgaaaaga
    22981 aaagcggagt gaaaacattt acacttgctt gagttatgtt atttatttga aattatggta
    23041 taatcgttca gttagaaaat aaattttgaa tattatagag gaaatcatga caaaattaag
    23101 agaagatatc cgtaacattg cgattatcgc ccacgttgac cacggtaaaa caaccctggt
    23161 tgacgaatta ttgaaacaat cagaaacgct tgatgcacgt actgaattgg cagagcgtgc
    23221 tatggactca aacgatatcg aaaaagagcg tggaatcacc atccttgcta aaaatactgc
    23281 cgttgcttac aacggaactc gtatcaacat tatggacaca ccaggacacg cggacttcgg
    23341 tggagaagtt gagcgtatca tgaaaatggt tgacggtgtt gtcttggtcg tagatgccta
    23401 tgaaggaacc atgccacaaa ctcgtttcgt attgaaaaaa gccttggaac aagaccttgt
    23461 cccaatcgtg gttgttaaca aaatcgataa gccatcagct cgtccagcag aagtagtgga
    23521 tgaagtcttg gaacttttca tcgagcttgg tgcagatgac gaccagcttg atttcccagt
    23581 ggtttatgct tcagcgatca acggaacttc ttcattgtca gatgatccag ctgaccaaga
    23641 agcgactatg gcaccaatct ttgacacgat tatcgaccat atcccagctc cagtagataa
    23701 ctcagatgag cctttgcagt tccaagtgtc acttttggac tacaatgact tcgttggacg
    23761 tatcggtatc ggtcgtgtct tccgtggtac agttaaggtt ggggaccaag ttaccctttc
    23821 taaacttgac ggtacaacta aaaacttccg tgttacaaaa ctcttcggtt tctttggttt
    23881 ggaacgtcgt gaaatccaag aagccaaagc gggtgacttg attgccgttt caggtatgga
    23941 agacatcttt gtcggtgaaa ccatcactcc gacagatgca gtagaagctc ttccaatcct
    24001 acacatcgat gagccaactc ttcaaatgac tttcttggtc aacaactcac catttgctgg
    24061 taaagaaggt aaatgggtaa cttctcgtaa ggtggaagaa cgcttgcagg cggaattgca
    24121 aacagacgtt tcccttcgtg ttgacccaac tgattcacca gataaatgga ctgtttcagg
    24181 acgtggagaa ttgcacttgt caatccttat cgaaacaatg cgtcgtgagg gctatgaact
    24241 tcaagtatct cgtccagaag ttatcgtaaa agaaatcgac ggtgttaaat gtgaaccatt
    24301 tgaacgtgta caaatcgaca ctccagaaga ataccaaggg tctgttatcc aaagcctttc
    24361 tgaacgtaaa ggtgaaatgt tggatatgat ttcaactggt aatggtcaaa ctcgtttggt
    24421 cttccttgtt ccagcgcgtg gtttgattgg atactcaact gagttcttgt caatgactcg
    24481 tggttacggt atcatgaacc ataccttcga ccaatacttg ccattgattc caggggaaat
    24541 tggtggacgt caccgtggtg cccttgtttc tatcgatgct ggtaaggcta caacttactc
    24601 aatcatgtct atcgaagaac gtggtacgat ctttgtcaac ccaggtactg aggtttatga
    24661 aggaatgatc atcggtgaaa actctcgtga aaatgacttg acagttaaca tcacgaaggc
    24721 aaaacaaatg accaacgttc gttcagctac taaggaccaa acagctgtta tcaagacgcc
    24781 tcgtatcttg acacttgaag agtctcttga gttcttgaac gacgatgagt acatggaagt
    24841 aacgcctgag tctatccgtt tgcgtaaaca aatccttaac aaagcagagc gtgagaaagc
    24901 taacaagaag aaaaaatcag ctgaataaga gctagaaaga gagaaagatg gtctatttag
    24961 tcctaggaat tttactgctc ctactctatg tatttgcgac accagaaagc attaaaggga
    25021 cagtcaatat cgtcgctatg gtatgtattt tagtggcact cttgatttta ttggttctat
    25081 cttttctgaa aatttttcaa ttaccaacag aaatattcct agcaatagcc atgttgctcc
    25141 tagcttactt tagtgttaga gacattacac tcatgccagt caaaaaaagt aaaagaagat
    25201 aaaaaagaga gttttggctc tcttttttgc taggaatttt acaagattgc aatttatttt
    25261 tgagttatca ccatctcttt tgtttggata atatgaatgg gaaaaacttg aataaaattc
    25321 gttaatggaa tctattttat atttggttag tactggttgc atattatttt gaaataaaac
    25381 tactatataa tattattcat agaggtaata tagtaaaata tctaaaaaat tcgatttttt
    25441 ccttgacaac aaataataaa aatgttattc ttatcacata agaaagcggt ttcaataaaa
    25501 gagagaggag gatttatttt gttgcattgt tgctcaaggt gtgatttttt tgaaagaaaa
    25561 aataaaatga aaacgaaaaa acatagatta cttgctctag ctcttatttc aagttttaca
    25621 ttattgggag ctgcatcagc tgctgtataa tatccagatg gaggagtatg gacatatgga
    25681 gaaggttcag gaggtggtta ggctttttca aattactatc atggtaaaaa atatcattat
    25741 tcatccatcg tgagcagatg ggatggtcat tctgataaag gagaagctcc tgctggaaaa
    25801 acctcctatg catggatttg gactaaatgg ggagaacaag tagcatttta ctgtgattat
    25861 gactaatcgt tcattgattt aaatcgttcc ccttgtaaga aattacaggg ggaattttgt
    25921 ttacaaggag tctaccaagg agtctactat gaagaaacta ttcatattat tatcaacttt
    25981 ttttctcagc ttcttccttg cttggattat tgtcttacgt gcgccacaat atttatatgc
    26041 aagctatgat tccgtttctt tacttcgtgt caaaaaagat actcaggaac cgacgcgtga
    26101 ggtatttgaa caggaattgg agaattttgc aaactcagaa cagagtttaa tagctagaag
    26161 aattgtagag ccgagtaagg atgggacgac tcactttact tatgcaactt atggtcaggg
    26221 aactttacca aaagaattcc aagaagctag ccaagaaagt cgtgaacgta gtgatccgct
    26281 aaatagttat ctccttttgt caggctcctt gacgaaagaa aagcttgccg ataaattagg
    26341 agatttgggt tataaagcaa gtgctgaccg aaagataccg ccctattttc ttgcttttcg
    26401 aatattacta aatcccctta ttttaattag tttagcaata tttggcttat ctttctttgc
    26461 tttagtgatt atcactcgga ttaaggaaat gagagcagca ggtataaaac tcttttctgg
    26521 tcagactctc ttatccatca tggggcattc tttatctact gatatcaaat agctccttct
    26581 atcagccctc ctttccttcc taggtggggg agtcgttctt tttagtcaag gtttgtttta
    26641 tcctatcttg ttagccacct atggttttgg gattagtttc tatctgttgt ttttattggc
    26701 gatttcaatt ttactaatgc ttctttatct aatgagtttg agttacaaag cattagttcc
    26761 cgttattaag gggagattac cccttaaacg cctgatgatt ttaaccctat tgtgtcagtt
    26821 ggttgctgtc tttacagtag gatacgctgt taagacaggt ttgacgtctt accaacgatt
    26881 gaaagaactt gaaatttcaa aacaagcatg gcaggataga gcagactatt atcaaatttc
    26941 ttttggctta ggtgatagag gaaaagatac agaaaatcag agcaagtggt atgcctttgc
    27001 caaggaagca atcgaagagg aacaagctct ttatgtaaag gataatctgc tccattttgc
    27061 caatccacaa ggaaaaaatg aacagggaga gacactggat acctatagtc cagatgctaa
    27121 tacgctctat gttagtccca gttatttgga caaggaaaag gtcgtggtag atgctgagac
    27181 caaacagaag ttagcccatc tccaaaaagg tgagtttatc ctcttgctcc cagaacattt
    27241 gcgctctcga gaagcagaac ttaagaaagt ttttgaagaa agattgagtt attatggaaa
    27301 atctggtgag gaggcaagtg ctcctttgga ttatgagatg aaagcgcacg ttagttatct
    27361 ttcaatggga gaaaagcggt ttgtttataa taacggtgag aatcccgtat ctactcagta
    27421 tttgactgat ccgattttag tggtattcac gccgacttct acaggtgata gttttatatc
    27481 cttatctagt tggtctatca atgctggaaa acaactcttt atcaaaggat atgagagtgg
    27541 gctagaactc ttgaagaaag ctggaattta tgagcaagta tcctatctta aagaaggaag
    27601 aagtgtttat ctaactcgtt ataatgaagt tcaaactgaa acagcaactt taatcttagg
    27661 agctattgtg gggatagcta gttccttatt actattttat tctgtcaatc ttctatattt
    27721 cgagcaattc cgccgagata tcttgattaa acgaatttca ggtttacgat tttttgaaac
    27781 acatgctcag tatatggtta gccaatttgc cagttttgta tttggtgcta gtctctttat
    27841 tttaagcagt cgagacttgg tgattggctt gctcacttta ttggtctttc tagctagtgc
    27901 agttttgacg ctttaccgtc aagcgcagaa agaatctcgt gtttctatga caattatgaa
    27961 aggaaaatag gatgattgaa ctaaagaata tatctaaaaa atttggaagc cgtcagctat
    28021 tttcagatac gaatcttcat tttgaaggtg ggaaaattta tgccttaatc ggtacaagtg
    28081 gctgtggtaa gacaacactc ttgaatatga ttggacgatt ggagccatat gacaaagggc
    28141 aaatcatcta tgatggcact tctcttaagg acatcaagcc ttctgttttc tttagagatt
    28201 acttaggata cttatttcaa gattttggct taattgaaag ccaaaccgtc aaagagaatc
    28261 tcaatctggg tttagttggt aaaaagttga aggaaaaaga gaaaatctct ttgatgaaac
    28321 aagctctaaa ctgtgtaaac ctctcttatt tggatttgaa gcaacctata tttgagttat
    28381 caggaggaga agcacaacgt gttgcactag cgaagataat tttaaaggat ccgcctttga
    28441 ttcttgcaga tgaaccaacc gcttccttag accccaaaaa ttctgaggaa ttactttcca
    28501 tcctagaatc tttaaaaaat ccgaatcgga ccattattat tgcgacccac aatcctctga
    28561 tttgggagca agtggatcag gtcattcgag ttaccgattt atcacataga tgatatggta
    28621 agattcagtt agaagaaaga gtcacaaaca cactttgtgg cttttttatt tccataaaaa
    28681 tggtaaaata gtaggagtag aaatggagtt cgagacatga aagtaataga tcaatttaaa
    28741 aataagaaag ttcttgtttt aggtttggcc aagtctggtg aatctgcggc tcgtttgttg
    28801 gacaagttag gtgccattgt gacagtaaat gatgggaaac cattcgagga caatccagct
    28861 gcccaatgtt tgctggaaga agggatcaag gtcattacag gtggccatcc tttggaactc
    28921 ttggatgaag agtttgccct catggtaaaa aatccaggta tcccctacag caatcccatg
    28981 attgaaaagg ctttggccaa gggaattcca gtcttgactg aggtggaatt ggcttatttg
    29041 atttcagaag caccgattat tggtatcaca ggatcgaacg gtaagacaac cacaacgact
    29101 atgattgggg aagttttgac tgctgctggg caacatggtc ttttatcagg gaatatcggc
    29161 tatcctgcca gtcaggttgc tcaaatagca tcagataagg acacgcttgt tatggaactt
    29221 tcttctttcc aactcatggg tgttcaagaa ttccatccag agattgcggt tattaccaac
    29281 ctcatgccaa ctcatatcga ctaccatggg tcattttctg aatatgtagc agccaagtgg
    29341 aatatccaga acaagatgac agcagctgat ttccttgtct tgaactttaa tcaagacttg
    29401 gcaaaagact tgacttccaa gacagaagcc actgttgtac cattttcaac acttgaaaag
    29461 gttgatggag cttatctgga agatggtcaa ctctacttcc gtggtgaagt agtcatggca
    29521 gcgaatgaaa tcggtgttcc aggtagccac aatgtggaaa atgcccttgc gactattgct
    29581 gtagccaagc ttcgtgatgt ggacaatcaa accatcaagg aaactctttc agccttcggt
    29641 ggtgtcaaac accgtctcca gtttgtggat gacatcaagg gtgttaaatt ctataacgac
    29701 agtaaatcaa ctaatatctt ggctactcaa aaagccttat caggatttga caacagcaag
    29761 gtcgtcttga ttgcaggtgg tttggaccgt ggcaatgagt ttgacgaatt ggtgccagac
    29821 attactggac tcaagaagat ggtcatcctg ggtcaatctg cagaacgtgt caaacgggca
    29881 gcagacaagg ctggtgtcgc ttatgtggag gcgacagata ttgcagatgc gacccgcaag
    29941 gcctatgagc ttgcgactca aggagatgtg gttcttctta gtcctgccaa tgccagctgg
    30001 gatatgtatg ctaactttga agtacgtggc gacctcttta tcgacacagt agcggagtta
    30061 aaagaataaa atatgaaaaa aattgtcttt acaggtgggg ggacggttgg acacgttacc
    30121 ctcaatcttt tgttaatgcc caagttcatc gaagatggtt gggaagtcca ctatatcggg
    30181 gacaagcgtg gtatcgaaca ccaagaaatc cttaagtcag gtttggatgt caccttccac
    30241 tccattgcga ctgggaaatt gcgtcgctat ttctcttggc aaaatatgct ggacgtcttc
    30301 aaagttggct ggggaatcgt ccaatcgctc tttatcatgt tgcgacttcg tccacagatc
    30361 cttttttcaa aggggggctt tgtctcagta ccgcctgtta tcgcagcgcg tgtgtcagga
    30421 gtgcctgtct ttattcacga atctgacctg tctatgggct tggccaataa aatcgcctat
    30481 aaatttgcga ctaagatgta ttcaaccttt gagcaagctt cgagtttgtc taaggttgag
    30541 catgtgggag cagtgaccaa ggtttcagat caaaaaaatc cagaaccaga tgaattggtg
    30601 gatattcaaa cccactttaa tcataaattg ccgactgtat tgtttgttgg cggttctgca
    30661 ggtgctcgtg tctttaacca attggtgaca gaccataaga aagaactaac agagcgctac
    30721 aatattatca atctaactgg agattctagc ctgaatgagt tgagccaaaa tctttttcgt
    30781 gttgactatg tgaccgatct ctatcaaccc ttgttggaat tggctgatat tgttgtgaca
    30841 cgaggtggtg ccaatacgat ttttgagctc ttggcgatag caaaattgca tgtcattgtg
    30901 ccgcttggtc gtgaagctag tcgtggtgac cagattgaaa atgcagctta ctttgtaaaa
    30961 aaaggctatg cagaagacct tcaagaaagc gatttgacct tggatagttt ggaagagaag
    31021 ctttctcact tactaagtca caaggaagat taccaagcta agatgaaagc ttctaaggaa
    31081 ttgaaatctc tagcagattt ttatcaattg ttgaaaaaag atttatcata aggaaagtaa
    31141 atgtcaaaag ataagaaaaa tgaggacaaa gaaatcctcg aagaattgaa agagttatca
    31201 gaatggcaga aacgaaacca agaatatcta aaaaagaagg ctgaagaaga agcggctcta
    31261 gctgaggaga aggaaaagga aagacaagct cggatgggag aagaatctga gaagtcagag
    31321 gacaaacagg accaggagag tgaaacagac caggaagatt cagaatcagc taaggaagag
    31381 tctgaagaaa aagtagcatc ctcagaggat gacaaagaga aagaagagaa agaagaacca
    31441 gagtctaaag agaaggagga acaggataaa aagcttgcta aaaaggctac aaaggaaaaa
    31501 ccagccaaag caaagattcc tggtatccat atcttgcgag ccttcacgat tttatttcca
    31561 agtctgcttt tattgattgt ctctgcctac ttgctcagtc cttatgcgac catgaaagat
    31621 attcgtgttg agggaacggt gcaaactaca gctgatgata ttcgacaggc ttcaggcatt
    31681 caggattcgg attatacgat taaccttctg ctagacaagg caaaatatga aaagcagatt
    31741 aagtctaact attgggttga atcagctcaa cttgtctatc aatttccaac taagttcact
    31801 attaaggtca aggaatatga tattgtggcc tactatattt ctggtgaaaa tcattatcct
    31861 attctttcca gtggtcagct tgagactagt tctgtgagcc tgaacagttt accagaaact
    31921 tatttatcag ttctctttaa tgatagtgaa caaatcaagg tttttgtctc agaacttgct
    31981 caaattagcc cagaactcaa ggcggctatc caaaaggtgg aattagcccc aagcaaggtg
    32041 acatccgatt taattcgatt gactatgaat gatttggacg aagtcttggt tccgctttct
    32101 gaaatgagca agaaactgcc ttattatagt aagattaagc cacaattgtc agaaccgagt
    32161 gtgattgaca tggaagctgg aatttacagt tacactgtgg cggataaatt aattatggaa
    32221 gctgaggaaa aagccaaaca agaggctaag gaagctgaga aaaaacaaga agaagaacag
    32281 aaaaaacaag aggaagagag caatcgaaac caaacgaccc agcgctcatc gcgtcgctag
    32341 gtttaccttt tctcttatag ttctttagtg accatgtttt tacttgacaa gtgctagtag
    32401 aaataataga atagtaaaaa acctttaaag cagtccagag aggcagctaa ggttagacgg
    32461 tgaaagggtg gagactaccc atttttcgtg gaaccttgct gttggcaggt tccttttttc
    32521 gtggcttctg ttggccagac tctctcacta gtaaaggtaa aaggagaaac ctatgcgaga
    32581 acatcgtcca gtcattgctc ttgattttcc tagttttgag gcggtcaagg aatttttagc
    32641 tcttttccca gcagaagaaa gcctttatct caaggtaggg atggagcttt attacgcagc
    32701 ggggcctgag attgtgtcct acttaaaagg tttgggtcat agtgtctttt tggatctcaa
    32761 acttcatgac attcctaata cagtcaagtc agccatgaag gtcttgtctc agcttggtgt
    32821 cgatatgact aatgtccatg cggctggtgg tgtagagatg atgaaggcgg cgcgtgaagg
    32881 ccttgggagt caagctaaat tgatcgctgt aactcagctc acatcaacgt cagaagctca
    32941 gatgcaggag tttcaaaata tccaaaccag tctgcaagag tctgtgattc actatgccaa
    33001 gaagacagct gaagctggct tggatggtgt tgtttgctcg gctcaggaag tacaagtcat
    33061 caagcaggct accaatccag attttatctg tctgacacca gggattcgtc cagctggtgc
    33121 tgcagttgga gatcaaaaac gagtcatgac acctgctgat gcctatcaaa tcggcagtga
    33181 ctatatcgta gtgggacgtc ccattaccca agctgaggat cctgttgcag cttatcatac
    33241 catcaaggat gaatggacac aggactggaa ttaaagaact agattagaaa aataaaagga
    33301 gaataccatg acacttgcta aagatatcgc tagccacctc ttgaaaatcc aagccgttta
    33361 cctcaaacca gaggaaccct tcacttgggc atctggtatc aagtcaccga tttacactga
    33421 taatcgtgtg acactagcct atccagaaac tcgtacccta attgaaaatg gttttgtgga
    33481 agctatcaaa gaagcctttc ctgaagtaga agtgattgca ggaactgcaa cagcagggat
    33541 tccacacgga gccattattg ctgataagat ggacttgcct tttgcctaca tccgtagcaa
    33601 accaaaagac cacggagctg gtaatcaaat cgaaggtcgc gtagctcaag gtcaaaaaat
    33661 ggtagtggtt gaagacctta tttcaacggg tggttcagtt cttgaagctg tagcagcagc
    33721 caagcgagaa ggagcagatg tgcttggagt tgtagcgatt ttcagctacc aattgccaaa
    33781 agcagataag aactttgcag atgctggtgt taaacttgtg acgctttcaa actatagcga
    33841 gcttatccat ctagcccaag aagaaggtta catcacgcca gagggccttg atcttctaaa
    33901 acgctttaaa gaagaccaag aaaattggca agaaggttag gtcagtaaga taaagagaga
    33961 tgaggctacc gagcctcttt tatcatttta tttaaaatat gacaatattt taaataaaat
    34021 gattgacaac gctttctttt gttgatataa tgaaaatgta atatgtatca aattgatcaa
    34081 tcaactatct tgtttatcac ttcttaggag gacgatgtca tgaaaagaag aaaaatatat
    34141 tccttttttg cgtagttaca attgcatcta gtttgtttct ccttacagtt ttagctagac
    34201 agattggaga ttatgattta acgttgccgc gttggggttc ggatacaact agtgagcttg
    34261 agaaagaaaa cgcctctgct ggaattaata ataatgacag cactggtggc ggtaaaaggt
    34321 taaatacctc tattcgtagc gcctatagtg ggtcagatat taccccggta tattcattgg
    34381 ggtctggctc taggattgtc atgtactata atggaggtgg tgacaattat attggttctg
    34441 gtactagatt agctatggcg ccacaatttg gaaatcatgt aagaattcat acttcaggtt
    34501 cttggaatcc agattcttat taacttactt gtcagagtaa gccttagaga tggttgattg
    34561 tgggtgtagc atgaaaaaag aatgctacac cctattttta ttataaggag gagtaaggat
    34621 ggaatttttc atttgtaatc ttgtacgagt cgttcaatca cctcgatttt atatgtcttt
    34681 atttttgacc cttctttgca tgagtttagg aaatttcctt gctttcaatg gtatttataa
    34741 aattgaaggt ttatcgattt tttttgccgc ttcttctatt cgaggatttt caccgattag
    34801 cctagtagct gcacttatct gtacactgcc ctattctagt cagataatag aggatgctga
    34861 gagtcatttt ctaacagcac aattgtgtcg aatttctaaa aagaagtatc tggctattgt
    34921 gggtagtact gtaattattt cttcttttct agtctttttt ctcccctatt tattattatt
    34981 aggaattaat cttttagtga ctccttatca ggaaatttat attggagatt atagtggtgc
    35041 cttaaaagaa ttatttgatt ccaatcagtt tctctatagt cttgtaacga ctctctggta
    35101 tggagtttgg ggcgctgtgt tctctatttt tggactagct agtgctttgc tagtgaagaa
    35161 aaaaatagga gctattttca tcccagttgc ctatatgatg gttggtggta ttttttgggc
    35221 tattttaggg ctatcttact tagaacctgt gacaacatta gctttgggat atcagaaaga
    35281 tatcagtctt tccttagtta gtgggcatct tgcttttatt ttatttgtta gttgtttggt
    35341 tgtttatggt acattttttc tacattcaga ggactacgta taatgaaaca atttgttcaa
    35401 ttttacaaaa aagatttttt atcagtattg gtttatttta tattactgct atcctgtgtt
    35461 ttatctagta cagtatattt attgcgctgt cgccaatatt caatccatcc aaatgtatta
    35521 gaatggatct tagttttact tcaagatatg acgactggag tatattgctt tccgttcaca
    35581 tatatattgt tcttttttta tttgatgaat aactatttta ataggttgga gtgtcgcatt
    35641 cgtctgaaat caattaagca ctttaccagt tttagtttca aattagcagc tcttagtacg
    35701 gggatttgga cggcgacttt atttttattg atttttctaa ttgcatttag taatggtttt
    35761 agcttctctt tggagataaa ggaggttgat tttttaagag aattttatgg tataagtatt
    35821 gcaaacaatg ctagtttctt tataggattt tttttctctt atatagcata ctatttcttt
    35881 ttatccttac ttactattag cagtttttct tggtttaaaa aatcaaacat gagcttagta
    35941 tttctgttta cttttttatt tgtagaatcc ttattctgga tttatcagtt ggacaatggg
    36001 ataattggat tattgccaat ttttcagtat atggtaaatt ccaatccgta tgcattgatt
    36061 tattggctta cattactatc tatcataatt ccattgactg tattttctgt tcatagaaac
    36121 tggaggagag tgtaaaagtt ggaaatggga aagttaagta gtcacatgtg gaggttgaat
    36181 cagataatct ataccaagta cttttggggt tatgttcttt tttggatatt gatttgttta
    36241 ggattatggt attggttaga aggaaatgat agacttgtta tagaaatttt aaaagggcct
    36301 aatctgagtc aaaactcttt tttagtctta tctatatggt tgcttcattg gtttattatt
    36361 catacatttt ttctagcagt tgtatatcgt agaagagcat ccgatttctt tatggaagtg
    36421 attcgatttt cttctattaa gctctggatt aggtatcaga tttggacctg ttttctttat
    36481 ggactcattt taatcatggt aaaagttcta gtgattcaat ttatgttaca gttaccaaac
    36541 tgggatatag gagttttgtt tatagttgat tctttgaatg cttgtgtgtt agtcttgttt
    36601 tgctttatgt tatacgcact aggagcgaat gtacaaatga actttgcttg cgttagtttc
    36661 tttttactca tgattgtgtt tggtggtcta tttgtaggaa atcgaactaa ttatctattt
    36721 tatattttga atcgagggaa tggagatata ggacgagatt tatttcttca gttgctattt
    36781 ttagtctttc tttttaaaag tattttctat ttcactcgtc aaaagaggag gtttatagaa
    36841 tgaatgaaat aatcatatta aaaaatattg agttgaaatt aaaaaaaaca tgtgtttttc
    36901 aaaaccttaa ttttagttgt aaacaggggg aaattatagg aattactggt gcgaatggct
    36961 cagggaaaag tgtattgttt aaattaatag ctggtttata tagtccgtct tatggagaag
    37021 tgttaatcaa tggggaaaat attgttcctg agagaaaaat tccagctaat ttgggagctt
    37081 tgattgaaga acctggtttt ataaattatt atagtggctt taagaattta caatatttgg
    37141 caagcatacg aggagtagtt ggtaatcagg aaatcaatga tacactgaaa atagttggtc
    37201 tatatgagca aaaagaccag aaagttaaaa cttattcgct aggtatgagg aaaaagctag
    37261 ggattgctca agcaattatg gagaatccct ctattctttt actagatgaa cctatgaatg
    37321 ccttggataa atcaagtgta gaaaatatga gaacattgtt tagaaagctc tctagtgaaa
    37381 aagggacaac aattttgatt gctagtcata gtgaagagga tattcgtatc ttatgtgata
    37441 aagtatatgc aatagaagat aaagtatgta cactgtgttc agattgaaca tcttagatag
    37501 actcaggatg ttataggtaa aatcttaaaa agggattgga gcttaaaatc cagtcccttt
    37561 taagagttaa tggccacctt caacaaccag gtcatctgct ttagcagcgt caccgtaggt
    37621 tgggtgaagt gttttttcat aggccttgtg gaagaagttt tccttgccta atttttcaat
    37681 atctttattg atgaagtcta gcaattcttg gttgcctttt tgaactgctg ccgcaatggt
    37741 atcgggatca ccgagggaag taattcctac ttcaaatcct ttattttcaa gcgcccaagc
    37801 tagaacttcc gtattgtcag ttgaaaaggc atctccacgt ccgtcaagaa gagcttggta
    37861 agagtcactg tattggtcgt atttttggag tttgatttct ggatgattct tttcaaaata
    37921 agtctcagca gtcgttcctt ttgtgacaat taaggtttta ccttcaagtt gtttgacgtc
    37981 tgtaatgaga ccagtcttag gtgatacgac acccagagaa actttcatat atggaagggc
    38041 aaaatcaact tgtttcttac gttcgtcagt tactgtaaag ttagcaagag taatatctac
    38101 cttgtttgaa atcaagtatt ccgcacggtt ggcagcatcg actgaaatgt atttaacctt
    38161 gacaccaagg tctttagcta gttggttccc tagttcaata tcgtagcctt ggtaagaacc
    38221 atcattgtca acgtagccaa acggtttttt atctccaaac acggcgattc gcagttcacc
    38281 gccttttttt gatttcatcg atagtgcgag ctttggcagt tgtttttcca gaggatgaac
    38341 cagcgtttcc acctgagcta caagcagtga taaagataag ggcaaaggca agtgctaaaa
    38401 cagttaagag tggtttgaat agtttcataa gaatctcctt tatagatatg agccaaattg
    38461 gctaaagtca aagacgttta aaaattcctg ggctcgtttg gtttgcggat tggtaaagaa
    38521 ggcttgagct gttccttctt cagcgatttt cccttggtcg aggaagataa tccggtcagc
    38581 aatggcttgg gcaaactgca tttcgtgggt tactaaaatc atggtacggc cttcttgggc
    38641 caaatcattg ataagttcca gcacctcacg caccatttct ggatccagcg aagcagtcac
    38701 ctcgtcaaaa aggatgattt ctggatgcat taggagggca cggacaattg caacacgttg
    38761 cttctgtcca ccagataatt gacgggcaaa gctatgttgt ttatccagca aaccgacacg
    38821 atctagtaat tgcaaagctt cttccgttac ttctttcttg tcccttcctt gagttttgat
    38881 agggcctagg atgaggtttt gtaagacatc cagatgggga aagagttcat aactttgaaa
    38941 gaccatgcca atcttttggc gaactaggtg aaaatttttt ttattttcaa cgatagactg
    39001 accatccaga aaaatatctc caccttgaat actttctaag ccgttgaggc aacgaaggag
    39061 ggtacttttc ccacaaccag atggccctag gatgacaaca acttcccctt ttttgatttc
    39121 tagagaaagt ccttggagga tgggattgtc tccgaaggat ttttttagtt ccttgatttc
    39181 taagatagtt tcagacattt agtttctcca atgtttttct aagtgagtgg atagtttgga
    39241 aatagggtag caaactgcga aatataagac tagaatggtt ccataaatcc aaaatgaagc
    39301 agttgggatg gtcaggcgat tgctatcgat gatttgttgt ccaactttgg tcacttccac
    39361 aaccccaatc aaaacaacta atgaagtggt tttaatcatc cgagtgacaa gattgatagc
    39421 ctgcggtagc agtcttctca agacttgtgg gatgatgatg tggtagtaaa gttgaacatt
    39481 agtcaagccg agtgcctgtc cactttcaaa ctgatgttta gggagagaag tgatagctcc
    39541 acgtaccaag tctcccattt cagctgttcc ccagagggta aaaacgataa tagctgaagt
    39601 ctcacctgag atattgatat taaagtttcg agccaagcca aagtaaacga tgaagagtag
    39661 caccagctgg ggcatgatac ggataaattc cagatacaat cgtgttaaaa atcgtatgat
    39721 tctagaatgg gaggtcatga tgattcccat gactgttccg aacatcatgg ataagaggac
    39781 agacaggatg gatatcccaa tcgtaacgcc caatccctgt aagattctca ggagattatt
    39841 tccttgaaag agtacttgga ttcccgaatc ctgcatggcg gagcctcctt tctatccagc
    39901 taaagaccag tgagatgggt agcagcatga tcagataagc aactaccaac atagctagcg
    39961 caatgtctgt ctcatagtag agaccaatca aatccttggc gacgtacatg aggtcggcca
    40021 aagccactgc tgagaaaaca gaggtttcct tgataaggaa aatgacattg gcactaaagg
    40081 aggggagtgc caccgctgtt gcttgcggaa gaaccacata gtaaaagacc tgtagaggtg
    40141 tcagaccaat agcgaggcca atctcctgct gggtttgact gatggcttcc agcccacttc
    40201 ggaaagattc tgccatatag gagtctccta aaaagacaag cccaagcgtt gcacagactt
    40261 ctgaagatag gacaatcccg attcggggaa gaccgaagta gagaaagaag agttgaatca
    40321 aaaggggcgt attacgtgac aattcaatgt aggctgtcgc tacttgcgac aaaacaagga
    40381 ttcgataatg tcggatgata ctaacgatta aaccgagcag aaaggatccc aaaattcccc
    40441 aaactgcaat atgcaaggtc agaaagaatg ccttttgata tagtggtaga tattgttcaa
    40501 caatggatca atccaaaaat agaacctccc atctagaaat aatacagtta ttgtagcact
    40561 taaaatcttc tttggataat atctattttt tattgccgtt ataaggattt ttatcataga
    40621 cataaaattt ctgaaatttc caaacaaaat attttaaaag ttttgaaaaa gagttaagat
    40681 atttttgtaa tacacaaagt aaacgcttac ttattaagga ggacatttta tgtcatacaa
    40741 aacaagcaat gcagaaggtc atgtagattt catcaatacc tatgatttgg agccaatggc
    40801 gcaacaagtt attcctaaag cagcatttgg ctatatcgct agtggggcgg gagatacttt
    40861 cacttctttc cagtgatttt agcgtcaggt tctttttagt ttttaaagat tatccgtgaa
    40921 tttcttgctt atttatgata aaatgggagt atcgcaaaaa atgactcatc gtattcaatt
    40981 ttgagtaaaa ctaggaggat cccatgtcta cagaacatat ggaagaacta aatgaccagc
    41041 agatcgttcg ccgtgaaaaa atggctgcgc tccgcgaaca aggaatcgat cctttcggaa
    41101 aacgttttga acgtactgca aattcacaag aattaaaaga taaatatacc aacctcgata
    41161 aagaacaatt acacgataaa aacgaaacag ctactatcgc aggacgcttg gtaaccaaac
    41221 gtggtaaagg aaaagttggt tttgcccacc ttcaagaccg cgaaggccag attcagatct
    41281 acgttcgtaa ggatgctgtc ggtgaagaaa actacgaaat cttcaaaaaa gcagaccttg
    41341 gtgacttcct tggtgtcgaa ggtgaagtga tgcgtacgga tatgggagaa ctctctatca
    41401 aggcaaccca catcacacac ttgtctaagg ctcttcgtcc tcttcctgag aaattccatg
    41461 gtttgacaga cgttgaaaca atttaccgta aacgttacct tgacttgatt tctaatcgtg
    41521 aaagctttga acgctttgtc actcgttcaa aaatcatctc tgaaatccgt cgttaccttg
    41581 accaaaaagg attccttgaa gtggaaacac ctgttcttca taatgaagcc ggtggtgctg
    41641 ctgcccgtcc atttatcacc caccacaatg cccaaaacat tgacatggtg cttcgtatcg
    41701 cgactgagct tcacttaaaa cgccttatcg tgggtggtat ggaacgtgtc tatgaaattg
    41761 gccgtatctt ccgtaacgaa ggaatggacg ctactcataa ccctgagttc acttctatcg
    41821 aagtttacca agcttatgca gacttccaag acatcatgga cttgactgaa ggcattatcc
    41881 aacacgctgc taaatcagtc aaaggtgatg gcccagtcaa ctaccaaggt actgaaatca
    41941 agattaacga accatttaag cgtgttcata tggtggatgc tatcagagaa attactggtg
    42001 tcgatttctg gcaagacatg actttggaag aagctaaagc tatcgctgct gagaagaaag
    42061 ttccagttga gaaacactac actgaggttg gtcacatcat caatgccttc tttgaagagt
    42121 ttgttgaaga aactttaatc caaccaacct ttgtctatgg acatccagta gctgtatctc
    42181 cactcgctaa gaaaaatcct gaagaccaac gctttactga ccgtttcgag ctctttatca
    42241 tgactaagga gtacggtaat gcctttactg agttgaacga cccaatcgac caacttagcc
    42301 gttttgaagc ccaagctaaa gccaaagaac ttggtgatga tgaagcgaca ggaatcgact
    42361 atgactacat tgaagctctt gaatacggta tgccaccaac aggtggtttg ggaatcggta
    42421 tcgaccgtct ctgcatgctc ctcactgata caacaactat ccgtgatgta ttgctcttcc
    42481 caacaatgaa ataaattctt atcctctggc tcttaccagg ggattttttg attcaaaaag
    42541 agactgaatt taaggagaaa atgaagtgta gtatattgaa gttgaaatag tacactttga
    42601 tttctaagac attgttagaa attggtttaa attccctaag caatttgtgc atgttttatt
    42661 tcattttacg atagtacgct gaaactgttc aaaaagtact agaaattgac ttggattccc
    42721 caattgattt gttcagattc actataaata aaaaattaat aagtgggata ggaagttagc
    42781 gtcaactagg atagtatctt gcttaaacag tatatatggg actgatataa gtccataggt
    42841 cctattagag gatgttctgg tgtcttattc acttgttttt tttatagtat tagtagatag
    42901 aatccgcaaa taaaaaagta gttcaaatgc ctggcagcaa aaaatctcaa cgattcactt
    42961 aatatagact aaggtttaga gtttaaggaa agtagggcta gtatattgta tgaaaaaata
    43021 agatggtttt taagcaaaac tcttgaaaat gattgaaaaa agagttatta tagttgtgta
    43081 gtaaaaagca aacgcttact taatcaagga gggcatttta tgtcatacaa aacaagcaat
    43141 gcagaaggtc atgtagactt catcaatacc tatgatttgg agccaatggc gcaacaagtt
    43201 attcctaaag cagcatttgg ctatatcgct agtggggcgg aagatacttt cactttaaga
    43261 gagaatatcc gcgcctttaa ccacaaactc atcgttcctc atacactttg cgatgttgaa
    43321 aatccaagta cagagattga atttgcaggt gaaaaactat cttcaccaat cattatggcg
    43381 cctgttgcgg cccataaatt agcgaatgaa cagggggaag tggcgactgc gcgtggtgtg
    43441 catgagtttg gttctcttta tacaaccagt tcttactcta ctgttgacct tccagagatt
    43501 tctgaagccc ttcaagggac accccattgg ttccaatttt actttagtaa ggatgacggt
    43561 atcaaccgcc acatcatgga tcgtgtgaag gctgaaggtt ataaagcgat tgtcttgacg
    43621 gcagatgcta ctgtaggggg gaatcgtgaa gtggataagc gtaatggttt tgtcttccca
    43681 gttggcatgc cgattgttga agaatacctg ccagaaggtg ctggtaaatc aatggacttt
    43741 gtttacaaat cagctaaaca acgcttgtct ccacgtgatg tagaatttat cgctgaatac
    43801 tcaggacttc ctgtgtatgt caagggacca caatgccgtg aggacgttga acgttcgctt
    43861 gctgcaggag cttctggtat ctgggtaacc aaccacggtg gtcgtcaaat cgacggtgga
    43921 ccagctgcct ttgactcgct tcaagaagtg gcagaagcag ttgataaacg tgtgccaatt
    43981 gtctttgact ctggtgttcg tcgtggtcaa catgtcttta aagccttggc ttcaggagca
    44041 gacttggtag ctattggtcg cccggttatc tatggcttgg ctctcggcgg tagtgttggt
    44101 gtgcgtcaag tctttgaaca cttgaatgcg gaattgaaga cagttatgca gttgtctgga
    44161 actcagacta ttgaagatgt taaacacttt aagctccgtc acaatccata caacccaacc
    44221 ttcccagttg accctcgtga cttaaaattg tattgataaa acagattgcc tccactgaat
    44281 gtggaggttt ttcttcgtgt attggaagaa taaatcgcta tcgaaaacca tagtaaaatg
    44341 gaataaaaac aggacaaatc aatcaggata tttaaatcga tttctaacaa tgttttagaa
    44401 gtagaggggt actattctag tttcaatcta ctatatataa agatattttt cggttaaata
    44461 tcttgctaag gctttcattt tttgctatac tggttcagta attaaataat agagacattt
    44521 ggggtgcttt aggctgagat aatacccatt gaacctgata cagttaagac tggcgaaggg
    44581 aaatgtgaac agttttttcg tatggtgaaa tgaacggtct aatcttgtaa gtcaactcta
    44641 attcttgatt gtaattggag ttttttgttt atataaactg gataggcttg tttagttagc
    44701 tctctgcaaa tactctcgat gtgttttaaa aggatcaagt ggaattacga ttttgcttga
    44761 tatttcttgg tgttttatta attactaaca agtaaagaga ggagaagtaa atatggaaac
    44821 acaagactat gcatttcagc caggtttgac tgttggagaa ttattaaaaa gcagtcagaa
    44881 ggattggcag gctgcaatca atcatcgttt tgttaaggaa ctttttgcgg ggacaattga
    44941 gaataaggtc ttaaaggact atctgattca agattatcac ttctttgatg ccttcttatc
    45001 catgctgggt gcctgcgtag ctcacgcaga taaacttgaa tccaagcttc gttttgccaa
    45061 gcaactaggc tttcttgaag cagatgaaga tggttatttc caaaaggctt ttaaagagtt
    45121 aaaagtagca gagaatgact atctagaagt gactttgcac cctgtaacaa aagcctttca
    45181 ggatctaatg tattgggcag tggcttcatc agactatgcc catcttttgg ttatgctggt
    45241 cattgcagaa ggtctctatt tagactgggg ttctaaagat ttggctctac ctgaagtcta
    45301 tattcattcg gaatggatca atctccacag aggtcctttc tttgcagagt gggttcaatt
    45361 tctggttgac gaactcaatc gtgtcggtaa aaatcgagaa gatttgacag aacttcagca
    45421 acgatggaat caagcagtcg ctttagaatt agcttttttt gatattggtt acgatgtcta
    45481 gagaaggctc atgatattta caaatttgat gaggtaagac tcttcgaaaa tctcttcaaa
    45541 ccacgtcagt ttcaccttgc cgtaggtatg gttactgact tcgtcagttc tatccacaac
    45601 ctcaaaacag tgttttgagc tgacttcgtc agtcttatct acaggttcaa agcagtgttt
    45661 tgagcaatct gcggttagct tcctagtttg ctctttgatt ttcattgagt ataaatcatt
    45721 caatgtaaat gaaaaaaatt cttaacgaaa gatagaaata aatcgaaatc agtagatcgt
    45781 ataaagtgaa aaggaaggat ttcaatatga caagtttaaa attattaaaa gaaaaagcac
    45841 cattggtcat ttgtataacc aatgatgtag taaaaaattt cacagcaaat ggattagtag
    45901 cactgggcgc ctcaccagcc atgagtgagt ttccagcaga tttagaggat ttgttaaagt
    45961 atgctggtgg tttattaata aacataggaa cattgacaga tgaaaattgg aaattatacc
    46021 aagctgctct gaaaattgca gagaaatata atgtcccagt agttttagat cctgtagcct
    46081 gtggagcagg agaatataga aaaaaagtag cagatgattt aatcaacaat tacaaactag
    46141 ctgcgattag ggggaatgct ggagagattg cctctttagt aggaatagat gtggcatcta
    46201 aaggagtaga tagtgcggga gtagataata ttgacgagat tgctctagca gcaaatgaga
    46261 agttcaatat tccaatagta gtaacaggtg aagtggatgc tattgcggta aatggagaag
    46321 tggtaacgat tcataatggt agtgccatga tgccaaaagt tattggaact ggatgtttat
    46381 taggggcagt ggtagcaagc tttatcggac tagaaaaagg tcaagaattg aaatcattag
    46441 aaacagcaat gttggtttac aatatcgctg gagaaatggc agaaaaacgt ccaaatggac
    46501 atcttcctgg gacatttaaa gttgaattta taaatgcctt atacgagatt acagatgaag
    46561 atgtaaagga attcaaaaga gtgaagtaag atgtttcata aagaattact aaaactatat
    46621 tttatttgtg gaacgactac ttgccaagga aaaaatctat atacagtcgt tgaggaagcc
    46681 ttaagaggtg gtataacctt atttcaattt cgagaaaaag gtgagggtgc tttagaaggc
    46741 ttagaaaaac ttgagctagc tatccaaatt aaagaacttt gtaaaaaata caatgtgccg
    46801 tttatcgtta atgatgatat cgatttggca atggaaattg acgctgatgg cgtacatgta
    46861 ggtcaagatg atattggtgt tgatgaaatt agaaaattga tgccagataa aataattggt
    46921 ctttctataa aaaacgagga agaatttcaa caatcaaaag ttgaatatgt agattatgtt
    46981 ggtgttggtc ctgtatttga tacccagtca aaggatgatg ctggtggtgc tataggttat
    47041 gaaggtgtta aattgatgag aaaactattg ccacaaatgc ccttagttgc aattggtggg
    47101 atacagacga aacatattaa agacattatg aagaccaatg ttgacggcgt ttcaatcatt
    47161 tcggcaatat cgtatgcaaa aaatatagaa aaaactgttc gggaaatgag tgaacaatag
    47221 atatctatcc ttggattcta agtaagtagg attttccttt tttaaaaagc tatgtctaga
    47281 ttcagcttga atagctaatt catcaaacag gtcatttgtt ttttgcaaaa gaaagatctg
    47341 ctgtctttgt gagtgcaagg ctgtatttcc agttcaattt cttgaactag tataaaatgt
    47401 gtgttataat aatcacataa ttaaataata aaggcatttg gggtgcttta ggctgagatg
    47461 atacccattg aacctgatac agttaagact ggcgaaggga aatgtgaaat gtttttttcg
    47521 tatgtcgaaa agaactgtct aatcttgtaa gctgaactct aattcgtatc tgtaattaga
    47581 gttttttctt ttacgaaact ggatgaagat gatatagtag attgaaataa gatgcgaaca
    47641 aatcaattag aaaattcaaa ttaatttcta gaaatatttt agcattcctg tgtactgttc
    47701 taaattcaat ctgctataca aagtatttag gtcggtcttc ttgagtgccc cacttttctt
    47761 ttaaaaaagg agttttttat gttgaaaaaa tggcagttaa aagatgttat cttgcttgct
    47821 ttcttgtcta tcttttttgg tggggttttc gttggttcag gatatgtgta taatattctc
    47881 agtctactct taacacctct tggtttgcag gcctttgcca atgaaatcct cttcggtctc
    47941 tggtgtatgg ctgcgcccat tgctgccatc tttgttccga gagtcggaag tgcaacgatt
    48001 ggagaagtgc tagctgcgct tgctgaagtc ctttatggta gccaatttgg tctaggagct
    48061 cttttgtctg gcttagttca aggtttggga agtgaatttg gttttatcgt aactaagaat
    48121 cgctatgaaa gttggctctc tctaactgct aatagtattg ggattacgct tgttagcttt
    48181 gtctatgaat acattaagtt aggttactac gccttttccc ttccgtttgt cctttcctta
    48241 cttgtggtac gttttatttc tgtttatttc ttctgtacca tcttggttcg tgccattgtc
    48301 aaactctatc atcagtttgc aactggagga aaagcataga tgggtctgga actacgagcg
    48361 attcagtccc caatcttctc tgagccgttt gattttactt ttcatgcgca agcctttacc
    48421 ttgttagttg ggagcagtgg ttcaggaaaa tccagccttt ttcaagtcat tgcccaagtt
    48481 agttctcttc cctatagcgg tcaagtcctg atagatggga gcgaggtcag tcagctttct
    48541 atcgtcgaac gtgtccagac ggttggtatt ctcttgcaaa atcctaatca tcaatttacc
    48601 atggagagct tgtttgagga gttggttttt accatggaaa atatcggcta tcaccttcag
    48661 gaaattgatt ctaaaatagc agaggttgtc cagcaatgtc gttgcaagga catcttgcac
    48721 cgtctcatcc atcacttatc aggtggggaa aagcaaaaag cagcgctggc tgtcctcttt
    48781 gccatgaatc ctagggtcta tctcttggat gagcccttcg cttccattga ccgcaagagt
    48841 agaatcgaga tattggagat tctaaaagag ttggctcttg atgggaagac agtcattttg
    48901 tgcgaccatg atttatctga ctataaagcc tatatcgact atatggttga gctaagagac
    48961 ggaaaactaa gggaagtgtt tcaaatccct tcctatgaga tgacacaggt tgcttcaaag
    49021 gaagttgctg ctagcccgga attattccat atgaaccgtg tgactggtga gcttggtaat
    49081 cgccccctct tttcgattgc tgatttcaca ttctatcaag ggatttcctg tatcctgggt
    49141 gacaatggtg tcgggaaatc aaccctcttt cggtctattc ttcaatttca aaagtataag
    49201 gggcgcattg catggaaggg gacagtcctg aaaaagaaaa agagtttgta ccgtgatctg
    49261 acgggtgttg ttcaggaagc tgagaagcag tttatccgag tcagtctgcg agaggagctt
    49321 caattagatg gacctgattc tgaaagaaat cagcggattt ttcaagcttt acgatatttt
    49381 gatttggagc aggcagtcga taagagtccc tatcaattaa gtggtggtca gcaaaaaatt
    49441 cttcagctcc tgaccatctt gaccagtaag gcttccgtga tcttgctaga tgaacctttt
    49501 gcaggtttgg atgatagagc ctgccattat ttttgcaagt ggattgtgga ggagaggaat
    49561 caaggaagaa gttttctgct cattagtcat cgtttagacc ctttgatttc tgtggttgat
    49621 tattggattg agatgactag tcagggtctt cggcatgtga aagaagtgac cattaccaaa
    49681 ccacttacat ctcagagtag caatacccaa ggggaggtga gatagtatgg tcaaagtagc
    49741 aacccagaca ccgattatca gtctcttctt gctgatttta tccttggaaa catctttcat
    49801 tccttcgatt gctctgaatc tttcggtagt cgcattttgt attctcttta tgttctatta
    49861 ccgtcgattt aaaatgttag cttggatgat catacttgcc attttaccat cttttgccaa
    49921 ctactgggca gttcagttac acggagatgc ttcacaggca gtcatgcttg gaacgagggc
    49981 ctttgtgaca gtttgtatcg gccttgtctt tgtttcctct atttcactaa aagagcttct
    50041 cttgtacttg gctcaaaagg ggctatcacg ctcttggtcc tatgccttga ttgtggtatt
    50101 caattctttt cctctcattc agcaagaaat caagtccctc aaagaagctt gcctattacg
    50161 tggtcaagaa ctacattttt ggtcgccctt gatttacagt aaggttctga tgacagtctt
    50221 taggtggcgc catctttacc tgagagctct atctgctcac ggatatgacg aacatgcaca
    50281 gttgaagaat agctatcgga ctttttatat tcctaaaaaa acaaaattaa tctacctgct
    50341 tttcttttta ttgcttcaaa ccagtctatt tttataaagg agttattatg gaatttacag
    50401 atattgcgat ggaattatcc aagaaagctt ggcaggcttc ctttcatcat ccctttattt
    50461 tacaattaca agaggggaat ttagaacctg ccattttccg ctattacctg attcaggatg
    50521 cctactatct gaaggttttc tcagaaatct atcatctttt ggctgataag acttcaaacc
    50581 aagagatgaa aagactcttg aaacaaaatg ctcagggttt agtggagggt gagttattta
    50641 ttcgccaaca atttttcaag gaattggaaa tcaacgacca ggaaatggag caacatccaa
    50701 tcgctccaac ctgttatcat tacatttctc atatttatag gcaatttgca gaaccgaact
    50761 tagccatagc ttttgcaagc ttgcttcctt gtccttggtt ataccatgat ataggcaaat
    50821 cacttaatct taaaccatca ccaaatcctc tctatcaaca atggattgaa acttatatta
    50881 cggatgagtt agagcaacag atcagagagg agggagcatt ggtcaatcag ctctatcgag
    50941 aaagtgatga gacagataag caaaaaatgc tagatgcctt ccacatcagt gttcatatgg
    51001 aagccaagtt ttgggagatg gcttaccaac accagacatg gaagagcgat ttacagtctt
    51061 tagaaaaagg agaagaatag aaacatgaga aagcaccaac tacaagttca caaattgacc
    51121 attttatcta tgatgattgc ccttgatgta gtccttacac ctatctttcg gattgaggga
    51181 atggcaccga tgtccagtgt agtcaatatt ctagcgggaa tcatgatggg acctgtttat
    51241 gccttggcta tggctacagt gacagccttt atccgtatga cgactcaagg gattccgcct
    51301 ttagctctca caggagcgac ttttggagcc cttctagcag gtctctttta taagtacggt
    51361 cgaaaatttt acttttctgc cttgggagaa attgtgggaa caggtattat tggttctatt
    51421 gtttcctatc ctgttatggt gctctttaca ggatcggctg ctaagcttag ttggtttatc
    51481 tacactcctc gatttttcgg agcaaccttg attggtacag cgatttcctt tattgcattt
    51541 agatttttaa tcaagcagga attctttaaa aaagtgcaag gatatttctt tgctgaaagg
    51601 atagaatgat gcaggcattg acaaatcctt ttcctatagg ctctagttcc ctcattcact
    51661 gtatgaccaa tgagatttct tgtgagatgc tggcaaatgg gattttggct ctgggatgca
    51721 aacctgtcat ggcagatgat ccccgtgaag ttcttgattt tactaagcaa agccaggctc
    51781 tcttcatcaa tttggggcat ttgtcagctg agaaggaaaa agcaatccgc atggcagctt
    51841 tgtatgcaaa ccaatcttct ctcccgatgg tagtagatgc ggttggcgta acgacttcat
    51901 ccattcgtaa gagcttagtt aaagaccttt tagactatag acctacggtc cttaaaggaa
    51961 acatgtcaga aattcgaagt cttgttggat taaagcatca cggcgttggg gtcgatgcga
    52021 gtgctaaaga tcaagaaacg gaggatttgc ttcaagtctt gaaagactgg tgtcagacct
    52081 atcctggtat gtcattctta gtcacaggtc ccaaggacct tattgtttcg gagaatcaag
    52141 ttgctgtact tgagaatggc tgtgcagaat tagactggat aacagggaca ggagatttgg
    52201 ttggagcctt aacagccgtt tttctcagcc aaggaaagac tggttttgaa gcttcttgct
    52261 tagcagtctc ttatctcaat atcgctgctg agaaaatagt tgttcaagga atgggattgg
    52321 aagaatttcg ttaccaagta ctcaatcagc tttcgctcct aagaagagat gaaaattggc
    52381 tagataccat caaaggagag gtttatgaat agagaagcac ttagactata tctggtaacc
    52441 aatcgctatc aagattccgt ggaaagcttt cttgcaaaag ttgagacggc ctgccgttca
    52501 ggggttacca tagtccaatt gcgagaaaaa aatctcacaa ccaatcaata ttatcaactg
    52561 gcaaaacaag tcaaggaaat aacagatgct tatcaggtac ccttgataat cgatgatcgg
    52621 ttggatgttt gtcttgcggt tgatgcagca ggtctgcata tcggagatga tgaattacca
    52681 gtttcggtag ctcgcaaagt cttgggtcct gaaaaaatcc tcggtgtcac cgctaaaacg
    52741 gttaaaagag ctctggaagc ggagaaatca ggtgcagatt acttgggtac aggagccatt
    52801 ttcccaacca ccaccaagga aaatgcgccc attactctga tatcgacctt gaaaacaatt
    52861 tgccaaacgg ttgccattcc agtagttgct attggcggct tgacatcaga gaatattgat
    52921 cagcttatgg acactggcat agctggtgta gctgttgtac gtgatttgat gcaagcagaa
    52981 gatattgagg caaaaacgca agccttttta acaaagttgc atgacattct ttcctaatta
    53041 atactcaatg aaaatcaaag agtaaactag aaagctagtc gcaggttgct caaagtactg
    53101 ccttgaggtt ttagataaga ctgacgaagt cagctcaaaa cagtgttttg aagttgcaga
    53161 tggaagctga cgtagtttga agagattttc gaagagtata aaaactctct aattccctta
    53221 aagtgggaac tagagagttt tttttcttaa tctttaaaag ttgtatggtt gactggacca
    53281 gaaccatgac cgagttgagg ggcatcttga atagcttttg tgataaaggc cttggcctta
    53341 tcaactgcct ggtaaagact cttgcccttg gctagttcag cagtaatcac tgcagcaaag
    53401 gtacatccag taccatgggt gtgacaggtt tgaattcgtg ggctttccca gacaaattgt
    53461 tcattcttgg taaagaggaa atctttagca ccacctttga gatgtccgcc tttgataacc
    53521 acagactgag gaccaaattc ttttaaaatc aggcgaccag cacgctgcat gtcttcgggg
    53581 tcatggattg aaaaaccaac aatctcttct gcttcaggaa gatttggcgt aataatagtt
    53641 gctagaggta gtaagtttgt tttgagatag tctctagcac ttgagtcaat caaggcatct
    53701 ccacttgtag caaccataac aggatcaagg acatagggac aatccagttt tttaagatag
    53761 gggtggatga tttccatgat ttcagtagta gccaacattc cagtttttac agcctgaggt
    53821 ggaatatcag aaaagacact ctccaattgg gctttcaaca tttgaggaga aacgtgctcg
    53881 attagctgaa cacctctggt attttgagcg acaagactgg ttacaacagc cattccatag
    53941 acatctctcg cttggaatga ctttaaatct gccataatgc cagcaccacc actagggtca
    54001 gtccctgcaa tggtcaaagc aacgggtaaa taagtcatct aaaacctccc aaccaactga
    54061 agtttgtatt cttaagaaca agctagtctg ttttagaaag gcaatagaag actgctagtc
    54121 cccattatca tttccacttc catcagctag cattatctag attgagtcag agggatctaa
    54181 cagtcgttaa tctcagcttt acgcacccct agtggttgtt ttcttttttc tttagtatag
    54241 catattttta ttgtttatat agtaatattt gactgcaaat cgtttttcaa atgattaaaa
    54301 ttctattttt cgaagaaaat attatttcta taattgacaa atgtagattt taagagtata
    54361 ctgatgagtg taattgacaa atgtagattt tggaggtatg gtaatgcaga tttcagatgc
    54421 agaatggcag gtcatgaaga ttatttggat gcagggggag cagaccagta cagatttgat
    54481 tagggttttg gcagagcggt ttgactggtc caagtccacg gttcagacac ttttggctcg
    54541 tctggttgag aaagagtgtt tgactcggaa aaaagaaggc aagtcctttg tttattcagc
    54601 ccttttaact ctagaccaaa gtcgggattt acttgtccaa gatatcaaag acaaggtttg
    54661 ttcccgtagg attaggaatt tgttggctga cttgattgta gaatgtgaat ttactcagac
    54721 tgacttggaa gacttggaag ctgtgatttc agagaagaaa tcaagtgctg taacagaagt
    54781 aagatgtaat tgtatgtaaa ggagacgtca tgttaaatag tattgtaacc attatttgta
    54841 ttgcccttat cgcatttatc ttgttttggt ttttcaaaaa gcctgaaaaa tctggacaaa
    54901 aagcccagca aaaaaacgga taccaagaga ttcgagtgga agtcatggga ggctatactc
    54961 ctgagttgat tgtcctaaag aaatcagtgc cagcacgcat tgtctttgac cgcaaggatc
    55021 cttcaccatg tctggatcaa attgtttttc cagattttgg tgtacatgcg aacctgccaa
    55081 tgggggaaga gtatgtagtg gaaatcacgc ctgaacaggc tggagagttt ggctttgctt
    55141 gtggtatgaa catgatgcac ggcaagatga ttgtagagta ggtggagact atgacagaaa
    55201 ttgtgaaagc aagcttagaa aatggcattc aaaaaatccg tatccgagct gaaaaaggct
    55261 atcatccagc ccatatccag cttcaaaagg gaattccagc tgagattacc tttcatcgtg
    55321 ctactccttc aaactgttat aaggaaattc tgtttgaaga agaaggtatc ttggaaccaa
    55381 tcggcgtaga tgaggagaaa gtcattcgtt ttacgcctca agaattaggg cgacatgaat
    55441 tttcttgtgg catgaagatg caaaagggaa gctatacagt cgttgagaag actcgaaaat
    55501 ctctatctct cctgcaacgt ttttggatta ctagtatctt tactgtgcct cttgtgattc
    55561 tcatgattgg gatgttggca ggtagcatta gtcatcaagt catgcattgg ggaacctttt
    55621 tagcaacaac gcctattatg ttagttgcag gtaagccata tatccagagt gcttgggcca
    55681 gttttaaaaa gcacaatgcc aacatggata ccttggttgc gctgggaact ctagtggctt
    55741 atttctatag cctagttgct ctctttgctg gtctccctgt ttacttcgaa agtgctggat
    55801 ttatcctctt tttcgttctt ttgggagcag tttttgagga aaaaatgaga aaaaatacgt
    55861 cccaagctgt ggagaaatta ctggacttgc aagctaaaac cgcagaagtc ttgagtgatg
    55921 atagttatgt ccaagttcct ttggaacaag tcaaggtagg cgacctgatt cgagtgcgtc
    55981 ccggtgaaaa gattgctgtt gatggtgtcg tagtagaagg tgtctctagt attgacgaat
    56041 ccatggtgac aggtgagagt ctgcctgtgg acaagacagt tggagatact gtcattggct
    56101 caaccatcaa tcatagtgga acgcttgtct ttagagcaga aaaagttggc tcagagactg
    56161 ttttggctca gattgtggat tttgtgaaga aagctcagac aagtcgtgcg ccgattcagg
    56221 acttgacgga taagatttca gggatttttg tcccagtagt tgtcatttta ggaatcatga
    56281 ccttttgggt ttggttcgtc ttgctcaggg atagtgtggt cgtgcttgga gctagctttg
    56341 tgtcctctct tctctacgga gtggcggttt tgattatcgc ctgtccttgt gccttgggac
    56401 ttgcaacacc gacagccctt atggtgggga caggacgtag tgccaagatg ggggttctcc
    56461 tcaaaaatgg aactgtctta caggaaatcc agaaagttca aactcttgtc tttgataaga
    56521 ccgggacttt gacggaaggg aaacctgtgg taacagatat catcggtgac gaagtagaag
    56581 tgtttggatt ggcagcctcc ttggaagatg cttctcaaca cccactggct gaggctatcg
    56641 ttaagcgagc gagtgaagct ggacttgagt ttcaaactgt tgaaaatttt caggccttgc
    56701 acgggaaagg tgtttcaggg cgaatcaatg gaaaacaagt tttacttgga aatgctaaaa
    56761 tgctggatgg catggatatt tctaatactt atcaagataa actagaagaa ctagaaaaag
    56821 aagctaagac agttgtgttt ttagctgttg acaatgaaat caaaggcttg cttgctttgc
    56881 aagatattcc taaggaaaat gctaagctag ccatcagtca gctaaaaaaa cgtggtctcc
    56941 gaacagtcat gctgacagga gacaatgctg gtgtggcgcg tgctattgca gatcaaatcg
    57001 gaattgaaga ggtcattgca ggcgtcttgc cagaagaaaa agcccatgaa atccataaac
    57061 tgcaacagtc agggaaagta gcctttgttg gggacggtat caatgacgct cctgccctta
    57121 gtgtagcaga tgtggggatt gctatgggag ctggaacaga tatcgccatc gagtcagcag
    57181 atttggtgtt gacaaccaat aatcttttag gagtggttcg tgcctttgat atgagtaaga
    57241 aaacctttca tcgaattcta ctcaatcttt tctgggcttt tatctacaat gttgtcggaa
    57301 ttccgattgc agcaggagtc ttttcaggtg ttggactggc tctcaaccca gaattggcag
    57361 gtctagccat ggcctttagt tctgtatctg ttctgaccag ttcccttctg ttaaatttta
    57421 gtaaaataga ctaaaagtaa tgactagatt tctttgttat aaaacagaaa tgacagaact
    57481 ttaaaaactg tattagaata gagaatagag agttttgagc agatttttag aaaagtcagc
    57541 ataaatatga tacagtggaa tagtaaaaat ttggagaacg tttccaattc tatgtaatcg
    57601 tattctccaa atctaaaaaa attgaaggag agttatcatt atgactcaag ggaaaattac
    57661 tgcatctgca gcaatgctta acgtattgaa aacatggggc gtagatacaa tctacggtat
    57721 cccatcagga acactcagct cattgatgga cgctttggct gaagacaaag atatccgctt
    57781 cttacaagtt cgccacgaag agacaggtgc tcttgcagcg gttatgcaag ctaaattcgg
    57841 cggctcaatc ggggttgcag ttggttcagg tggtccaggt gcgactcact tgattaacgg
    57901 tgtttacgat gcagctatgg ataacactcc attcctagcg atccttggat cacgtccagt
    57961 taacgaattg aacatggatg ctttccaaga gcttaaccaa aacccaatgt acaacggtat
    58021 cgctgtttac aacaaacgtg tagcttacgc tgagcaattg ccaaaagtaa ttgacgaagc
    58081 ctgccgtgct gcaatttcta aaaaaggtcc agctgttgtt gaaattccag taaacttcgg
    58141 tttccaagaa atcgacgaaa actcatacta cggttcaggt tcatacgaac gctcattcat
    58201 cgctcctgct ttgaacgaag ttgaaatcga caaagctgtt gaaatcttga acaatgctga
    58261 acgcccagtt atctatgctg gatttggtgg tgttaaagct ggtgaagtga ttactgaatt
    58321 gtcacgtaaa atcaaagcac caatcatcac aactggtaaa aactttgaag ctttcgaatg
    58381 gaactatgaa ggtttgacag gttctgctta tcgtgttggt tggaaaccag ccaacgaagt
    58441 ggtctttgaa gcagacacag ttcttttcct tggttcaaac ttcccatttg ctgaagttta
    58501 cgaagcattc aagaacactg aaaaattcat ccaagttgat atcgaccctt acaaacttgg
    58561 taaacgtcat gcccttgacg cttcaatcct tggtgatgct ggtcaagcag ctaaagctat
    58621 ccttgacaaa gtaaacccag ttgaatcaac tccatggtgg cgtgcaaacg ttaagaacaa
    58681 ccaaaactgg cgtgattaca tgaacaaact cgaaggtaaa actgagggtg aattgcaatt
    58741 gtatcaagtt tacaatgcaa tcaacaaaca tgctgatcaa gacgctatct actcaatcga
    58801 cgtaggtaac actactcaaa catctactcg tcaccttcac atgacaccta agaacatgtg
    58861 gcgtacatct ccactctttg cgacaatggg tattgccctt cctggtggta tcgctgctaa
    58921 gaaagacaat ccagatcgcc aagtatggaa catcatgggt gacggagcat tcaacatgtg
    58981 ctacccagac gttatcacaa acgttcaata cgaccttcca gttatcaacc ttgtcttctc
    59041 aaatgctgag tacggcttca tcaagaacaa atacgaagat acaaacaaac acttgtttgg
    59101 tgtagacttc acaaacgctg actacgctaa aattgcggaa gctcaaggag ctgttggatt
    59161 cacagttgac cgtatcgaag acatcgatgc agttgttgca gaagctgtta aattgaacaa
    59221 agaaggtaaa actgttgtca tcgatgctcg catcactcaa caccgtccac ttccagtaga
    59281 agtacttgaa ttggatccaa aacttcactc agaagaagct atcaaagcct tcaaggaaaa
    59341 atacgaagca gaagaactcg taccattccg tctcttcttg gaagaagaag gattgcaatc
    59401 acgcgcaatt aaataattcc tctcgccgaa aatcaaatat gaaacttgta gactttattc
    59461 tttgattttc atagagcaga actttaaaag atcggagcaa tccggtcttt ttatggagga
    59521 gagtaaatga atttaaatca attagatatt atcgtttcaa atgttcccca agtctgtgct
    59581 gacttggagc atattttgga taaaaaggca gattatgctg atgatggttt tgctcagttt
    59641 acgattggta gtcactgcct tatgttgtca caaaatcatt tggttccttt ggaaaacttt
    59701 cagtcaggaa tcattattca tatcgaggtt gaggatgtag accagaacta caaacggttg
    59761 aacgagcttg gtataaaggt tttacacgga ccaactgtaa ccgattgggg aacagagtcc
    59821 ttattagttc aaggacctgc tggtctagtg cttgattttt atcgtatgaa ataggtcgcg
    59881 tagtcatttg acgttaacct tagctatttt taaaatagaa attgagaata tgaactattg
    59941 aaagatcgga gcaatccggt ctttttatat aaagaaattg catataatac tcatatgctt
    60001 tcaaaaagca ttctagtcca tctccgatta acgatggact ttatcacctc cttctccagt
    60061 ccttgtatga catcttgaag ttgattcatg acatcttcca aagttcgaaa ggccttattc
    60121 ttaaatccac gtttacgaat ctctttccac acttgttcaa tgggttcatc tctggtgtg
//
LOCUS       DAVHTH010000005        58774 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.005, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000005 DAVHTH010000000
VERSION     DAVHTH010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 58774)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 58774)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..58774
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.005"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            complement(164..304)
                     /locus_tag="VVR63_000311"
     CDS             complement(164..304)
                     /locus_tag="VVR63_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="blpT protein"
                     /protein_id="HEU6128368.1"
                     /translation="MEDKKLIQLLSKLNKSYQNCKQVTADDIRLQELLNTTMQELKKQ
                     KS"
     gene            473..1015
                     /locus_tag="VVR63_000312"
     CDS             473..1015
                     /locus_tag="VVR63_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HEU6128369.1"
                     /translation="MKLNIQEIRKQSEGLNFEQTLDLVDDLRARNQEILDVKDILAVG
                     KVQYEDRMYFLDYQLSYTIVLASSRSMEPVELVESYPVTEVFMEGATNQLDQEVLDDD
                     LVLPIENGALDLAESVSDNILLNIPIKVLTAEEEAGQGFVSGNDWQIMTEEEYQAQQA
                     VKKEENSPFAGLQGLFDGDE"
     gene            1015..1620
                     /gene="nth"
                     /locus_tag="VVR63_000313"
     CDS             1015..1620
                     /gene="nth"
                     /locus_tag="VVR63_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HEU6128370.1"
                     /translation="MVLSKKRARKVLEEIIALFPDAKPSLDFTNHFELLVAVMLSAQT
                     TDAAVNKATPGLFVAFPTPQAMSVATESEIASHISRLGLYRNKAKFLKKCAQQLLDDF
                     DGQVPQTREELESLAGVGRKTANVVMSVGFGIPAFAVDTHVERICKHHDIVKKSATPL
                     EVEKRVMDILPPEQWLAAHQAMIYFGRAICHPKNPECDQYP"
     gene            1855..2376
                     /gene="pyrR"
                     /locus_tag="VVR63_000314"
     CDS             1855..2376
                     /gene="pyrR"
                     /locus_tag="VVR63_000314"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HEU6128371.1"
                     /translation="MKTKEVVDELTVKRAITRITYEIIERNKDLNKIVLAGIKTRGVF
                     IAHRIQERLKQLENLSVPVVELDTKPFRDDVKSGEDTSLVSVDVTDREVILVDDVLYT
                     GRTIRAAIDNIVGHGRPARVSLAVLVDRGHRELPIRPDYVGKNIPTSRSEEIIVEMTE
                     LDDQDRVLITEEA"
     gene            2395..3318
                     /locus_tag="VVR63_000315"
     CDS             2395..3318
                     /locus_tag="VVR63_000315"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HEU6128372.1"
                     /translation="MSENQQALNHVVSMEDLTVDQVMKLIKRGIEFKNGAQLPYEDHP
                     IVSNLFFEDSTRTHKSFEVAEIKLGLERLDFDVKTSSVNKGETLYDTILTLSALGVDV
                     CVIRHPEVDYYRELIASPTITTSIINGGDGSGQHPSQSLLDLMTIYEEFGHFEGLKVA
                     IAGDLDHSRVAKSNMQILKRLGAELFFAGPEEWRSQEFADYGQFVTIDEIIDQVDVMM
                     FLRVQHERHDSGAVFSKEDYHAQHGLTQERYDRLKETAILMHPAPINRDVEIADHLVE
                     APKSRIVQQMTNGVFVRMAILESVLASRNAN"
     gene            3368..4447
                     /gene="carA"
                     /locus_tag="VVR63_000316"
     CDS             3368..4447
                     /gene="carA"
                     /locus_tag="VVR63_000316"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HEU6128373.1"
                     /translation="MTKRILVLEDGTVFEGKAFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQILTFTYPLVGNYGINRDDYESIIPTCKGVVVFEEARRASNWRNQMTLDEFLK
                     AKKIPGISGIDTRALTKIIRKHGTMRATLTHVGDSMDHVTDQLQATVLPTDNIKQVST
                     KTSYPAPGVGLSVVLVDFGLKHSILRELSKRNCNVTVVPYSTTAEEILHLNPDGVMLS
                     NGPGNPEDVPQALDMIRGVQGKIPIFGICMGHQLFAMANGAKTYKMKFGHRGFNHAVR
                     EIATGRVDFTSQNHGYAVSREDLPEHLIITHEEINDKSVEGVRHRYQPAFSVQYHPDA
                     APGPHDASYLFDEFIEMMEVFKQSN"
     gene            4759..7935
                     /gene="carB"
                     /locus_tag="VVR63_000317"
     CDS             4759..7935
                     /gene="carB"
                     /locus_tag="VVR63_000317"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HEU6128374.1"
                     /translation="MPKRTDIQKIMVIGSGPIIIGQAAEFDYAGTQACLSLKEEGYEV
                     VLVNSNPATIMTDKEIADKVYIEPITLEFVTRILRKEGPDALLPTLGGQTGLNMAMEL
                     SKNGILDELGVELLGTKLSAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEAVAFAA
                     TIGYPVIVRPAFTLGGTGGGMCANEKELREITENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPAQTMSDYENQMLRDASLSIIRALK
                     IEGGCNVQLALDPNSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEV
                     INPVTGSTYAMFEPALDYVVAKIPRFPFDKFEKGERRLGTQMKATGEVMAIGRNIEES
                     LLKACRSLEIGVHHNEIPELAAVSDDTLIEKVVKAQDDRLFYVSEAIRRGYTPEEIAE
                     LTKIDIFYLDKLLHIFEIEQELGAHPQDLEVLKTAKLNGFSDRKIAELWGTTDDKVRQ
                     LRLENKIVPVYKMVDTCAAEFDSETPYFYSTYGWENESIKSDKESVLVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDL
                     EQPKGVIVQFGGQTAINLAEPLAKAGVTILGTQVADLDRAEDRDLFEQALKELDIPQP
                     PGQTATNEEEAALAARKIGFPVLVRPSYVLGGRAMEIVENEEDLRSYMRTAVKASPDH
                     PVLVDSYIVGQECEVDAISDGKNVLIPGIMEHIERAGVHSGDSMAVYPPQTLSQKVQE
                     TIADYTKRLAIGLHCLGMMNIQFVIKDEKVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQSLSELGYQNGLYPESTRVHIKAPVFSFTKLAKVDSLLGPEMKSTGEVMGSD
                     ATLEKALYKAFEASYLHLPTFGNVVFTIADDAKEEALNLARRFQNIGYGILATEGTAA
                     FFASHGLQAQPVGKIGDDDKDIPSFVRKGRIQAIINTVGTKRTADEDGEQIRRSAIEH
                     GVPLFTALDTANAMLKVLESRSFVTEAI"
     gene            complement(8210..9019)
                     /locus_tag="VVR63_000318"
     CDS             complement(8210..9019)
                     /locus_tag="VVR63_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEU6128375.1"
                     /translation="MQYLEKKEIKEIQLALLDYIDETCKKHDIPYFLSYGTMLGAIRH
                     KGMIPWDDDIDISLYREDYERLLKIIEEENHPRYKVLSYDTSSWYFHNFASILDTSTV
                     IEDHVKYKRHDTSLFIDVFPIDRFTDLSIVDKSYKYVALRQLAYIKKSRAVHGDSKLK
                     DFLRLCSWYALRFVNPRYFYKKIDQLVKNAVTNTPQYEGGVGIGKEGMKEIFPVDTFK
                     ELILTEFEGRMLPVPKKYDQFLTQMYGDYMTPPSKEMQEWYSHSIKAYRKN"
     gene            complement(9021..9824)
                     /locus_tag="VVR63_000319"
     CDS             complement(9021..9824)
                     /locus_tag="VVR63_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEU6128376.1"
                     /translation="MKQLTIEDAKQIELEILDYIDTLCKKHNINYIINYGTLIGAVRH
                     EGFIPWDDDIDLSMPREDYQRFINIFQKEKSKYKLLSLETDKNYFNNFIKITDSTTKI
                     IDTRNTKTYESGIFIDIFPIDRFDDPKVIDTCYKLESFKLLSFSKHKNIVYKDSLLKD
                     WIRTAFWLLLRPVSPRYFANKIEKEIQKYSRENGQYMAFIPSKFKEKEVFPSGTFDKT
                     IDLPFENLSLPAPEKFDTILTQFYGDYMTLPPEEKRFYSHEFHAYKLED"
     gene            complement(9834..11321)
                     /gene="tacF"
                     /locus_tag="VVR63_000320"
     CDS             complement(9834..11321)
                     /gene="tacF"
                     /locus_tag="VVR63_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV teichoic acid flippase TacF"
                     /protein_id="HEU6128377.1"
                     /translation="MKSIKLNALSYMGIRVLNIIFPILTGTYVARVLDRTDYGYFNSV
                     DTILSFFLPFATYGVYNYGLRAISNVKDNKKDLNRTFSSLFYLCIACTILTTAVYILA
                     YPLFFIDNPIVKKVYLVMGIQLIAQIFSIEWVNEALENYSFLFYKTAFIRILMLVSIF
                     LFVKNEHDIVVYTLVMSLSTLINYLISYFWIKRDIKLVKIHLSDFKPLFLPLTAMLVF
                     ANANMLFTFLDRLFLVKTGIDVNVSYYTIAQRIVTVIAGVVTGAIGVSVPRLSYYLGK
                     GDKEAYVSLVNRGSRIFNFFIIPLSFGLMVLGPNAILLYGSEKYIGGGILTSLFAFRT
                     IILALDTILGSQILFTNGYEKRITVYTVFAGLLNLGLNSLLFFNHIVVPEYYLLTTML
                     SETSLLVFYIIFIHRKQLIHLGHIFSYTVRYSLFSLSFVAIYFLINFVYPVDMVINLP
                     FLINTGLIVLLSAISYISLLVFTKDSIFYEFLNHVLALKNKFKKS"
     gene            11657..12364
                     /locus_tag="VVR63_000321"
     CDS             11657..12364
                     /locus_tag="VVR63_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HEU6128378.1"
                     /translation="MIYAGILAGGTGTRMGISNLPKQFLELGNRPILIHTIEKFVLEP
                     SIEKIVVGVHGDWVSHAEDLVDKYLPLYKERIIITKGGADRNTSIKKIIEAIDAYRPL
                     TPEDIVVTHDSVRPFITLRMIQDNIQLAQNHDAVDTVVEAVDTIVESTNGQFITDIPN
                     RAHLYQGQTPQTFRCKDFMDLYGSLSDEEKEILTDACKIFVIKGKDVALAKGEYSNLK
                     ITTVTDLKIAKSMIEKD"
     gene            12369..13391
                     /locus_tag="VVR63_000322"
     CDS             12369..13391
                     /locus_tag="VVR63_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HEU6128379.1"
                     /translation="MINQIYQLTKPKFINVKYQEEAIDQENHILIRPNYMAVCHADQR
                     YYQGKRDPKILNKKLPMAMIHESCGTVISDPTGTYEVGQKVVMIPNQSPMQSDEEFYE
                     NYMTGTHFLSSGFDGFMREFVSLPKDRVVAYDAIEDTVAAITEFVSVGMHAMNRLLTL
                     AHSKRERIAVIGDGSLAFVVANIINYTLPESEIVVIGRHWEKLELFSFAKECYITDNI
                     PEELAFDHAFECCGGDGTGPAINDLIRYIRPQGTILMMGVSEYKVNLNTRDALEKGLI
                     LVGSSRSGRIDFKNAIQMMEVKKFANRLKNILYLEEPVREIKDIHRVFATDLNTAFKT
                     VFKWEV"
     gene            13408..14277
                     /gene="licA"
                     /locus_tag="VVR63_000323"
     CDS             13408..14277
                     /gene="licA"
                     /locus_tag="VVR63_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline kinase LicA"
                     /protein_id="HEU6128380.1"
                     /translation="MEKIIKEKISSLLSQEEEVLSVEQLGGMTNQNYLAKTTNKQYIV
                     KFFGKGTEKLINRQDEKYNLELLKDLGLDVKNYLFDIEAGIKVNEYIESAITLDSTSI
                     KTKFDKIAPILQTIHTSAKELRGEFAPFEEIKKYESLIEEQIPYANYESVRNAVFSLE
                     KRLADLGVDRKSCHIDLVPENFIESPQGRLYLIDWEYSSMNDPMWDLAALFLESEFTS
                     QEEETFLSHYESDQTPVSHEKIAIYKILQDTIWSLWTVYKEEQGEDFGDYGVNRYQRA
                     VKGLASYGGSDEK"
     gene            14267..15145
                     /locus_tag="VVR63_000324"
     CDS             14267..15145
                     /locus_tag="VVR63_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HEU6128381.1"
                     /translation="MKSKNGVPFGLLSGIFWGLGLTVSAYIFSIFTDLSPFVVAAAHD
                     FLSIFILLAFLLVKEGKVRLSIFLNIRNVSVIIGALLAGPIGMQANLYAVKYIGSSLA
                     SSVSAIYPAISVLLAFFFLKHKISKNTVFGIVLIIGGIIAQTYKVEQVNSFYIGILCA
                     LVCAIAWGSESVLSSFAMESELSEIEALLIRQVTSFLSYLVIVLFSHQSFTAVANGQL
                     LGLMIVFAAFDMISYLAYYIAINRLQPAKATGLNVSYVVWTVLFAVVFLGAPLDMLTI
                     MTSLVVIAGVYIIIKE"
     gene            15157..15846
                     /locus_tag="VVR63_000325"
     CDS             15157..15846
                     /locus_tag="VVR63_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NTP transferase domain-containing protein"
                     /protein_id="HEU6128382.1"
                     /translation="MKAIILAAGLGTRLRPMTENTPKALVQVNQKPLIEYQIEFLKEK
                     GINDIIIIVGYLKEQFDYLKEKYGVRLVFNDKYADYNNFYSLYLVKEELANSYVIDAD
                     NYLFKNMFRNDLTRSTYFSVYREDCTNEWFLVYGDDYKVQDIIVDSKAGRILSGVSFW
                     DAPTAEKIVSFIDKAYVSGEFVDLYWDNMVKDNIKELDVYVEELEGNSIYEIDSVQDY
                     RKLEEILKNEN"
     gene            15942..16790
                     /gene="dprA"
                     /locus_tag="VVR63_000326"
     CDS             15942..16790
                     /gene="dprA"
                     /locus_tag="VVR63_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HEU6128383.1"
                     /translation="MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADIS
                     GCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDCYPWDLSEIYDAPVLLFYKGNLD
                     LLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
                     TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRG
                     VIVAEAKMRSGSLITCERAMEEGRDVFAIPGSILDGLSDGCHHLIQEGAKLVTSGQDV
                     LAEFEF"
     gene            17679..18722
                     /locus_tag="VVR63_000327"
     CDS             17679..18722
                     /locus_tag="VVR63_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00341 family protein"
                     /protein_id="HEU6128384.1"
                     /translation="MTNNKLYSLIEFRNKIYEELELSRSDLAILLCAMLIASIGLNMD
                     STPVIIGAMLISPLMTPILGVGLSLAIFDFKLLRKSFKILAIQILASLIASTLYFYLS
                     PISYASSEIVARTSPTIWDVLIAFVGGIAGIIGARKKETNNIVPGVAIATALMPPLCT
                     VGYAIASANLKFIIGSSYLFLINCSFIVIATYIGVRLMMVKKHYFKDNEEDSKMRRIL
                     LLVAVLLMIPSFISATTLVRETLKKESLKKFISEQFQGYNILKKTYSKKTHTLKLTIS
                     GNYLTEEELDMISSKRGDYGLSDVSVQVSQLSDSEQLSKEELVEYFFQYIKDKEAKEK
                     EKANKFDTESEEQ"
     gene            18889..20976
                     /gene="topA"
                     /locus_tag="VVR63_000328"
     CDS             18889..20976
                     /gene="topA"
                     /locus_tag="VVR63_000328"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HEU6128385.1"
                     /translation="MATATKKKKSTVKKNLVIVESPAKAKTIEKYLGRNYKVLASVGH
                     IRDLKKSSMSVDIENNYEPQYINIRGKGPLINDLKKEAKKANKVFLASDPDREGEAIS
                     WHLAHILNLDENDANRVVFNEITKDAVKNAFKEPRKIDMDLVDAQQARRILDRLVGYS
                     ISPILWKKVKKGLSAGRVQSIALKLIIDRENEINAFQPEEYWTVDAVFKKGTKQFHAS
                     FYGVDGKKMKLTSNNEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAAN
                     KINFRTRKTMMVAQQLYEGINIGSGVQGLITYMRTDSTRISPVAQNEAASFITDRFGS
                     KYSKHGSKVKNASGAQDAHEAIRPSSVFNTPESIAKYLDKDQLKLYTLIWNRFVASQM
                     TAAVFDTMAVKLSQKGVQFAANGSQVKFDGYLAIYNDSDKNKMLPDMVVGDVVKQVNS
                     KPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTIETIQKRYYVRLAAKRFEPTEL
                     GEIVNKLIVEYFPDIVNVTFTAEMEGKLDDVEVGKEQWRRVIDAFYKPFSKEVAKAEE
                     EMEKIQIKDEPAGFDCEVCGSPMVIKLGRFGKFYACSNFPDCRHTQAIVKEIGVECPS
                     CHQGQIIERKTKRNRLFYGCNRYPECEFTSWDKPVGRDCPKCGNFLMEKKVRGGGKQV
                     VCSKGDYEEEKIK"
     gene            21082..21441
                     /locus_tag="VVR63_000329"
     CDS             21082..21441
                     /locus_tag="VVR63_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaN family protein"
                     /protein_id="HEU6128386.1"
                     /translation="MRLIYLIIGFLSLALAIVGVVLPLLPTTPFLLLSIACFSRSSKR
                     FEDWLYHTKLYQTYVADFRETKSITRERKKKIIVSIYILMGISIYFAPLLPVKIGLGA
                     LTIFITYYLFKVIPDKE"
     gene            21534..22166
                     /locus_tag="VVR63_000330"
     CDS             21534..22166
                     /locus_tag="VVR63_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HEU6128387.1"
                     /translation="MIYEFCAENVTLLEKAMQAGARRIELCDNLAVGGTTPSYGVTKA
                     AVELAANYDTTIMTMIRPRGGDFVYNDLEIAIMLEDICLTAQAGSQGVVFGALTADKK
                     LDKPNLEKLIAASKGMEIVFHMAFDELSDEDQPEAIDWLSQAGVTRILTRAGVSGDSL
                     EKRFVHYHRILEYAKGKIEILPGGGIDLDNRQTFIDQVGVTQLHGTKVVF"
     gene            22210..22866
                     /locus_tag="VVR63_000331"
     CDS             22210..22866
                     /locus_tag="VVR63_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HEU6128388.1"
                     /translation="MFEIFKSYQFNQEKAHDYGFIENSEVWTYSCQILQGDFVMTVSI
                     TADNVNFQVFDQETGDLYPHVHMESMRGSFVGNVREACLEILYQIRKACFDVQDFICH
                     QTKRIMTQVQEKYGNQLEYLWEKSPDTAVLRHEGNQKWYAVLMKISWNKLEKGREGQV
                     EAVNLKHDQVANLLSQKGIYPAFHMSKRYWISVSLDDTLSDEEVLELIEKSWNLTSKK
                     "
     gene            22885..23517
                     /locus_tag="VVR63_000332"
     CDS             22885..23517
                     /locus_tag="VVR63_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001010941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HEU6128389.1"
                     /translation="MNFQLAKYSLLKKFLENIGFTTLEEYGAIFKYLIENVKTDRQII
                     CSPHCHDDLGMAVANSLAAVKNGAGRVEGTINGIRERAENAALEEIAVALNIRQDYYQ
                     VETSIVLNETINTSEMVSRFSGIPVPKNKAVVGGNTFSHESGIHQDGVLKNPLTYEII
                     TPELVGVKIPLGKLSGRHAFVEKLRELALDFTEEDIKPLFAKFKALADKK"
     gene            23545..23979
                     /locus_tag="VVR63_000333"
     CDS             23545..23979
                     /locus_tag="VVR63_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase I"
                     /protein_id="HEU6128390.1"
                     /translation="MVAGTMVENPEGFHFDDLQLQTHADNDIEALVSLANMDGEKVEF
                     NATGQGSVEAIFNAIDKFFNQSVRLVSYTINAVTDGIDAQDRVLVTVENRDTETIFNA
                     AGLDFDVLKASAIAYINANTFVQKENAGEMGRSVSYHDMPSV"
     gene            23991..25028
                     /gene="leuB"
                     /locus_tag="VVR63_000334"
     CDS             23991..25028
                     /gene="leuB"
                     /locus_tag="VVR63_000334"
                     /EC_number="1.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="HEU6128391.1"
                     /translation="MAKKIVALVGDGIGPEIMEAGLEVLEALAEKTGFDYEIDRRPFG
                     GADIDAAGPPLPDETLKASREADAILLAAIGSPQYDGAAVRPEQGLMALRKELNLYAN
                     IRPVKIFDSLKYLSPLKPERISGVDFVVVRELTGEIYFGDHILEERKARDINDYSYEE
                     VERIIRKAFEIARNRRKIVTSIDKQNVLATSKLWRKVAEEVAQDFPDVTLEHQLVDSA
                     AMLMITNPAKFDVIVTENLFGDILSDESSVLSGTLEVMPSASHSENGPSLYEPIHGSA
                     PDIAGQGIANPTSMILSVAMMLRDSFGRYEDAERIKHAVETSLAAGILTRDIGGQAST
                     KEMTEAIIARL"
     gene            25025..25294
                     /locus_tag="VVR63_000335"
     CDS             25025..25294
                     /locus_tag="VVR63_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HEU6128392.1"
                     /translation="MKLDEKITLVLLIWNVIIFLIYGIDKFKARRRTWRIQEKILLIL
                     ALTCGGFGAWLAGITFHHKTRKWYFKTVWFLGMVTTLVALYFIWR"
     gene            25298..25657
                     /gene="leuD"
                     /locus_tag="VVR63_000336"
     CDS             25298..25657
                     /gene="leuD"
                     /locus_tag="VVR63_000336"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HEU6128393.1"
                     /translation="MAGSSREHAAWVLADYGFKVVIAGSFGDIHYNNELNNGLLPIVQ
                     PREVREKLAQLKPTDQVTVDLEQQKIISPVEEFTFEIDSEWKHKLLNSLDDIGITLQY
                     EELIAAYEKQRPAYWQD"
     gene            25819..26440
                     /locus_tag="VVR63_000337"
                     /pseudo
     CDS             25819..26440
                     /locus_tag="VVR63_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002276310.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="translation factor (SUA5)"
     gene            26604..28517
                     /locus_tag="VVR63_000338"
     CDS             26604..28517
                     /locus_tag="VVR63_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrB family protein"
                     /protein_id="HEU6128394.1"
                     /translation="MNKRKVSLEDFYKWYSLNKEELLNKATVGEKFNDKLKEEFLQEW
                     PLDRILTMSIDEYVIGKGQQNKSLCYALEKGKYKNLFLGISGGSASKFGIYWNKKTNK
                     YKDQANNEISELDQRFSKLKSDLYEIIKEGIRFNFENPIFDMKRSTNEFIGRSAMVTK
                     LLCIYTEGDPFFGVNINSQKEFWNHFVSQTNQGGPYLQNHKIIELVSKTYPELEPSKL
                     GTMLFEYSKLFMENKEDNSTMDSSNNFSHQLTQSLLKSPNLILRGAPGTGKTYLAKEI
                     AKELTDGNEDQIGFVQFHPSYDYTDFVEGLRPVSNGDGAIEFRLQDGIFKDFCQKAKE
                     TQLIGGQDNFDEAWDSYLEYINVAEEKEYITKTSYLSVNSRQNLSVNYDSGVPGWSLP
                     SKYVYELYKDKNYNKQEYYKSGGKTVLETLRKRFGLKDYVSPTEIDTDKKFVFIIDEI
                     NRGEISKIFGELFFSIDPGYRGEKGSVSTQYANLHETDEKFYIPENVYIIGTMNDIDR
                     SVDTFDFAMRRRFRFVEVTAEGQVGMLDKELNIHAEEAKIRLRNLNAAIENVQELNSH
                     YHIGPSYFLKLKDVDFDYELLWSDYIKPLLEDYLRGSYDEVETLETLKKAFELTNNDQ
                     TGQQDTGDNDADN"
     gene            28504..29742
                     /locus_tag="VVR63_000339"
     CDS             28504..29742
                     /locus_tag="VVR63_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HEU6128395.1"
                     /translation="MRITDNQHKIAKEDFVAEYPKLSQALLDRTLDNLSREDNIFIFP
                     NDLTHTPDLDKDQKIFETVNQKIKTGNVIGFLGYGQERLTISSRFSDESNDHFLHYLL
                     NKVLHINLTSLDVALSREERLYQLLMYLFPKYLQAAIRKGLYKEYHRFSHNDSHVKGV
                     IDVRNHLKKNLPFTGNIAYTTREFTYDNPLMQLVRHTIECIKNQKSIGQGVLDNLSTS
                     RENVSEIVRVTPSYKLADRAKIIRMNKIKLIRHAYFREYRKLQELCLVILSREKHGLG
                     PQAQRVHGILFDVAWLWEEYVYTLLPKGFVHPRNKDKTDGISVFSVGKRKVYPDFYDR
                     ERKIVLDAKYKKLELTEKGINREDLFQLISYSYILKAEKAGLVFPSKDKVIDNEIGNL
                     AGYGLFESLRMPHSIVHFVK"
     gene            29976..30962
                     /locus_tag="VVR63_000340"
     CDS             29976..30962
                     /locus_tag="VVR63_000340"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HEU6128396.1"
                     /translation="MLNEFPIFDYEDIQLIPNKCVIKSRAEADTSVTLGNHTFKLPVV
                     PANMQTILDENVAEQLAKGGYFYIMHRFDEAGRIPFIKRMHNQGLIASISVGVKDYEY
                     DFVRQLKTDAPEYITIDIAHGHADSVISMIQHIKKELPDTFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGASMIMIGSLFAGHIESPGKTIEVDGEQFKEYYGSASQYQKGAYKNVEGKRIL
                     LPAKGHLQDTLTEMEQDLQSAISYAGGRQVADLKHVDYVIVKNSIWNGDASH"
     gene            31026..31097
                     /locus_tag="VVR63_000341"
     tRNA            31026..31097
                     /locus_tag="VVR63_000341"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:31059..31061,aa:Arg,seq:ccg)
     gene            31280..31978
                     /locus_tag="VVR63_000342"
     CDS             31280..31978
                     /locus_tag="VVR63_000342"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HEU6128397.1"
                     /translation="MKELQTVLKNHFAIEFADKNLLETAFTHTSYANEHRLLKISHNE
                     RLEFLGDAVLQLLISEYLYKKYPKKPEGDLSKLRAMIVREESLAGFARDCQFDQFIKL
                     GKGEEKSGGRNRDTILGDAFEAFLGALLLDKDVAKVKEFIYQVMIPKVEAGEFEMITD
                     YKTHLQELLQVNGDVAIRYQVISETGPAHDKVFDVEVLVEGKSIGQGQGRSKKLAEQE
                     AAKNAVEKGLDSCI"
     gene            31969..35508
                     /gene="smc"
                     /locus_tag="VVR63_000343"
     CDS             31969..35508
                     /gene="smc"
                     /locus_tag="VVR63_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HEU6128398.1"
                     /translation="MYLKEIEIQGFKSFADKTKVVFDQGVTAVVGPNGSGKSNITESL
                     RWALGESSVKSLRGGKMPDVIFAGTESRKPLNYASVVVTLDNHDGFIKDAGQEIRVER
                     HIYRSGDSEYKIDGKKVRLRDIHDLFLDTGLGRDSFSIISQGKVEEIFNSKPEERRAI
                     FEEAAGVLKYKTRRKETESKLQQTQDNLDRLEDIIYELDNQIKPLEKQAENARKFLDL
                     EGQRKAIYLDVLVAQIKDNKAELDSTEEELAQVQELLTSYYQKREKLEEENQTLKKQR
                     QDLQAEMAKDQGSLMDLTSLISDLERKLALSKLESEQVALNQQEAQARLATLEDKRSS
                     LSQEKSDKESSLALLEGNLVQNNQKLNRLEAELLAFSDDPDQMIELLRERFVALLQEE
                     ADVSNQLTRIENELENSRQLSQKQADQLEKLKEQLAIAKEKASQQKEELETAKEQVQK
                     LLADYQAIAKEQEEQKTSYQAQQSQLFDRLDNLKNKQARAQSLENILRNHSNFYAGVK
                     SVLQEKDRLGGIIGAVSEHLTFDMHYQTALEIALGASSQHIIVEDENAATKAIDFLKR
                     NRAGRATFLPLTTIKARTISSQNQDAIAVSPGFLGMADELVTFDTRLEAIFKNLLATT
                     AIFDTVEHAREAARQVRYQVRMVTLDGTELRTGGSYAGGANRQNNSIFIKPELEQLQK
                     EIAEEEASLDSEEVALKTLQDEMARLTESLEAIKSQGEQARIQEQGLFLAYQQTSQQV
                     EELETLWKLQEEEIDRLSEGDWQADKENCQERLAAIASDKQNLEAEIEEIKSNKNAIQ
                     ERYQNLQEELAQARLLKTELQGQKRYEVADIERLGKELDNLNIEQEEIQRMLQEKVDN
                     LEKVDTDLLNQQAEEAKTQKTNLQQGLIRKQFELDDIEGQLDDIASHLDQARQQNEEW
                     IRKQTRAEAKKEKVSERLRHLQSQLTDQYQISYTEALEKAHELENLNLAEQEVKDLEK
                     AIRSLGPVNIEAIDQYEEVYNRLDFLNSQRDDILSAKNLLLETITEMNDEVKERFKST
                     FEAIRESFKVTFKQMFGGGQADLILTEGDLLTAGVEISVQPPGKKIQSLNLMSGGEKA
                     LSALALLFSIIRVKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRKGT
                     MAAADSIYGVTMQESGVSKIVSVKLKDLESIEG"
     gene            35505..36299
                     /locus_tag="VVR63_000344"
     CDS             35505..36299
                     /locus_tag="VVR63_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU6128399.1"
                     /translation="MTIKLVATDMDGTFLDGNGRFDMDRLKSLLASYKEKGIYFAVAS
                     GRGFLSLEKLFADVRDDIIFIAENGSLVEYQGQDLYEATMSRDFYLVTFEKLKTSPYV
                     DINKLLLTGNKGSYVLDTVDETYLKVSQHYNENIQKVASLEDITDDIFKFTTNFTEET
                     LEDGEAWVNENVPGVKAMTTGFESIDIVLDYVDKGVAIVELVKKLGITMDQVMAFGDN
                     LNDLHMMQVVGHPVAPENARPEILELAKTVIGHHKDQSVIAYMEGL"
     gene            36299..37117
                     /locus_tag="VVR63_000345"
     CDS             36299..37117
                     /locus_tag="VVR63_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU6128400.1"
                     /translation="MADIKLIALDLDGTLLTTDKRLTDRTKETLKAARDRGIKVVLTT
                     GRPLKAMDFFLHELGTDGQEDEYTITFNGGLVQKNTGEILDKTVFSYDDVARLYEETE
                     KLSLPLDAISEGTVYQIQSDQESLYAKFNPALTFVPVDFEDLSSQMTYNKCVTAFAQE
                     PLDAAIQKISPELFDQYEIFKSREMLLEWSPKNVHKATGLAKLISHLGINQSQVMACG
                     DEANDLSMIEWAGLGVAMQNAVPEVKAAANVVMPMTNDEEAVAWAIEEYVLKEN"
     gene            37121..38410
                     /gene="ftsY"
                     /locus_tag="VVR63_000346"
     CDS             37121..38410
                     /gene="ftsY"
                     /locus_tag="VVR63_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HEU6128401.1"
                     /translation="MGLFDRLFGKKEEPKIEEVVKEALENLDLSEDVDPTFTEVEEVP
                     QEEAEVEIVEQAVFQEEEIQDTVEESQDSEPAVGVSQEEIEELPNSEELPEEEKLEHE
                     GTVEENNSEVLEPERPQTEETVQEKYDRSLKKTRTGFGARLNAFFANFRSVDEEFFEE
                     LEELLIMSDVGVQVASNLTEELRYEAKLENAKKPDALRRVIIEKLVELYEKDGSYDES
                     IHFQDNLTVMLFVGVNGVGKTTSIGKLAHRYKRTGKKVMLVAADTFRAGAVAQLAEWG
                     RRVDVPVVTGPEKADPASVIFDGMERAVAEGIDILMIDTAGRLQNKDNLMAELEKIGR
                     IIKRVVPEAPHETFLALDASTGQNALVQAKEFSKITPLTGIVLTKIDGTARGGVVLAI
                     REELNIPVKLIGFGEKIDDIGEFNSENFMKGLLEGLI"
     gene            complement(38456..39943)
                     /locus_tag="VVR63_000347"
     CDS             complement(38456..39943)
                     /locus_tag="VVR63_000347"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HEU6128402.1"
                     /translation="MSSKVIVTIFGASGDLAKRKLYPSLFRLYKSGNLSKHFAVIGTA
                     RRPWSKEYFESVVVESILDLADSTEQAQEFASHFYYQSHDVNDSEHYIALRQLQAELN
                     EKYQAEHNKLFFLSMAPQFFGTIAKHLKSENIVDGKGFERLIVEKPFGTDYATASKLN
                     DELLATFDEEQIFRIDHYLGKEMIQSIFAVRFANLIFENVWNKDFIDNVQITFAERLG
                     VEERGGYYDQSGALRDMVQNHTLQLLSLLAMDKPAIFTKDEIRAEKIKVFKNLYHPTD
                     EELKEHFIRGQYRSGKIDGMKYISYRSEPNVNPESTTETFTSGAFFVDSDRFRSVPFF
                     FRTGKRLTEKGTHVNIVFKQMDSIFGEPLAPNILTIYIQPTEGFSLSLNGKQVGEEFN
                     LAPNSLDYRTDATATGASPEPYEKLIYDVLNNNSTNFSHWDEVGASWKLIDRIEELWA
                     ENGAPLHDYKAGSMGPQASFDLLEKFGAKWTWQPDIAYRQDGRFE"
     gene            complement(40092..40832)
                     /locus_tag="VVR63_000348"
     CDS             complement(40092..40832)
                     /locus_tag="VVR63_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU6128403.1"
                     /translation="MAKLKIDVNDLHKHYGKNEVLKGITTKFYEGDVVCIIGPSGSGK
                     STFLRSLNLLEEVTSGHITVNGYDLTEKTTNVDHVRENIGMVFQHFNLFPHMSVLDNI
                     TFAPIEHKLMTKEEAEELGMELLEKVGLADKANANPDSLSGGQKQRVAIARGLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKELAEQGMTMIIVTHEMGFARQVANRVIFTADGEF
                     LEDGTPDQIFDNPQHPRLKEFLDKVLNV"
     gene            complement(40832..42997)
                     /locus_tag="VVR63_000349"
     CDS             complement(40832..42997)
                     /locus_tag="VVR63_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEU6128404.1"
                     /translation="MKKKFLAFLLILFPIFSLGIAKAETIKIVSDTAYAPFEFKDSDQ
                     TYKGIDVDIINKVAEIKGWNIQMSYPGFDAAVNAVQAGQADAIMAGMTKTKEREKVFT
                     MSDTYYDTKVVIATTKSHKISKYDQLTGKTVGVKNGTAAQRFLETIKDKYGFTIKTFD
                     TGDLMNNSLSAGAIDAMMDDKPVIEYAINQGQDLHIEMDGEAVGSFAFGVKKGSKYEH
                     LVTEFNQALAEMKKDGSLDKIIKKWTASSSSAVPTTTTLAGLKAIPVKAKYIIASDSS
                     FAPFVFQNSSNQYTGIDMELIKAIAKDQGFEIEITNPGFDAAISAVQAGQADGIIAGM
                     SVTDARKATFDFSESYYTANTILGVKESSNIASYEDLKGKTVGVKNGTASQTFLTENQ
                     SKYGYKIKTFADGSSMYDSLNTGAIDAVMDDEPVLKYSISQGQKLKTPISGTPIGETA
                     FAVKKGANPELIEMFNNGLANLKANGEFQKILDKYLASESSTASTSTVDETTLWGLLQ
                     NNYKQLLSGLGITLALALISFAIAIVIGIIFGMFSVSPYKSLRVISEIFVDVIRGIPL
                     MILAAFIFWGIPNFIESITGQQSPINDFVAGTIALSLNAAAYIAEIVRGGIQAVPVGQ
                     MEASRSLGISYGKTMRKIILPQATKLMLPNFVNQFVIALKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFKMYAILAIFYLVIITLLTRLAKRLEKRIR"
     gene            43170..44123
                     /locus_tag="VVR63_000350"
     CDS             43170..44123
                     /locus_tag="VVR63_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU6128405.1"
                     /translation="MKNKRIFKDFQASKMSLNIYTSLLLAFVFVFIGEFVAYTLYGIS
                     LLALIGLARNFGEAGQNLASYLQTLHQSLTDKTSDFRLILGLLAFGFILNTVFRWTRK
                     VEKRPIRTLGFYRENFLSNLLKGFSLGLALFLLTLLGLVVLGQYRLESIHLNPYSLAF
                     VVFTIPFWILQGTAEEVVARAWLLPQLASRTNLKLAILISSLFFTLLHMGNSGLTPLS
                     LVNLFLFGVAMALYLLKTDTVWGVAGIHGAWNFAQGNLFGILVSGQPSGTSLMTFLPQ
                     GNQDWLSGGSFGIEGSIMTSLVLLLLIVYLANKLKKENERM"
     gene            44200..46188
                     /gene="uvrB"
                     /locus_tag="VVR63_000351"
     CDS             44200..46188
                     /gene="uvrB"
                     /locus_tag="VVR63_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HEU6128406.1"
                     /translation="MINHITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMG
                     ATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
                     DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFR
                     VEFFGDEIDRIREVEALTGQVLGEVDHLAIFPATHFVTNDDHMEVAIAKIQAELEEQL
                     AVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDGRSEGEPPYTLLDFF
                     PDDFLIMIDESHMTIGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKN
                     ERTFITTLTKKMAEDLTDYFKEMGIKVKYMHSDIKTLERTEIIRDLRLGVFDVLVGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADTVTQSMQ
                     RAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVAKEEDKEVDINSLNKQE
                     RKELVKKLEKQMQEAVEVLDFELAAQIRDMMLEVKALD"
     gene            46198..46761
                     /locus_tag="VVR63_000352"
     CDS             46198..46761
                     /locus_tag="VVR63_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6128407.1"
                     /translation="MIYLRKLKREDLMSLWEMAYSQLNPVWKQYDAPYYDDYQYFSNF
                     KEFELQKSESILSNSNRLGIFVDDKLVGTVSRYWVCKQTRWMELGIGIYDKKFWNTGI
                     GKVAMLQWIDRTFQDYLELEHLGLTTWSGNIGMMKLAEKLRMKKEAHIPKVRYYQGKY
                     FDSIKYGILREDWEKINDGYYQINGNS"
     gene            46727..47215
                     /locus_tag="VVR63_000353"
     CDS             46727..47215
                     /locus_tag="VVR63_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6128408.1"
                     /translation="MTVIIKSMETPKEIEGKSLVHWQTWRESYDDLLPAEFQDTMTLE
                     RCRFFSQKYPENTLIAMDGVKVVGFISYGNFRDETIQAGEIIALYVLKDYYGKGIAQK
                     LMKAALTALNHFSEIFLWVLKDNKRAIAFYQKMGFTFDGQEKILELGKPIKEKRMVFY
                     SK"
     gene            47289..47756
                     /locus_tag="VVR63_000354"
     CDS             47289..47756
                     /locus_tag="VVR63_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEU6128409.1"
                     /translation="MSRSQLTILTNICLIEDLETQRVVMQYRAPENNRWSGYAFPGGH
                     VENDEAFAESVIREIYEETGLTIQNPQLVGIKNWPLDTGGRYIVICYKATEFSGTLQS
                     SEEGEVSWVQKDQIPNLNLAYDMLPLMEMMEAPDKSEFFYPRRTEDDWEKKIF"
     gene            complement(47753..48268)
                     /locus_tag="VVR63_000355"
     CDS             complement(47753..48268)
                     /locus_tag="VVR63_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HEU6128410.1"
                     /translation="MTKDRKQALLQLLKEAPKALNGQSLAEHFHVTRQVIVQDIAILR
                     ADGAPILSTNRGYIYKQIDTNPYVHKLFKVKHEVEEIGQELLAIVDNGGHVQNTLIDH
                     PVYGEIETLLKLSCRRDVQHFLEQVEHSDFRPLSELTDGIHYHLVEAETQQDLHYIEE
                     ALDQLGYLVKD"
     gene            complement(48280..48807)
                     /locus_tag="VVR63_000356"
     CDS             complement(48280..48807)
                     /locus_tag="VVR63_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEU6128411.1"
                     /translation="MNTRKKTQFMTMTALLTAIAILIPIVMPFKIVIPPASYTLGSHI
                     AIFIAMFLSPLMAVFVILASSFGFLMAGYPMVIVFRAFSHISFGALGALYLQKFPDTL
                     DKPKSSWVFNFVLAVVHALAEVLACVLFYATSGTNVENMFYVLFVLVGFGTIIHSMVD
                     YTLALAVYKVLRKRR"
     gene            complement(49089..49652)
                     /locus_tag="VVR63_000357"
     CDS             complement(49089..49652)
                     /locus_tag="VVR63_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEU6128412.1"
                     /translation="MKKRSNIAPIAIFFATMLVIHFLSSLIFNLFPFPIKPTIVHIPV
                     IIASIIYGPRVGVTLGFLMGLLSLTVNTITILPTSYLFSPFVPNGNIYSAIIAIVPRI
                     LIGLTPYLVYKLMKNKTGLILAGALGSLTNTIFVLGGIFFLFGNVYNGNIQLLLATVI
                     STNSIAELVISAILTLAIVPRLQTLKK"
     gene            complement(49636..50187)
                     /gene="coaC"
                     /locus_tag="VVR63_000358"
     CDS             complement(49636..50187)
                     /gene="coaC"
                     /locus_tag="VVR63_000358"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HEU6128413.1"
                     /translation="MANILLAVTGSIASYKSADLVSSLKKQGHQVTVLMTQAATEFIQ
                     PLTLQVLSQNPVHLDVMKEPYPDQVNHIELGKKADLFIVVPATANTIAKLAHGFADNM
                     VTSTALALPSHIPKLIAPAMNTKMYDHPVTQNNLKTLETYGYQLIAPKESLLACGDHG
                     RGALADLTIILERIKETIDEKTL"
     gene            complement(50199..50888)
                     /gene="coaB"
                     /locus_tag="VVR63_000359"
     CDS             complement(50199..50888)
                     /gene="coaB"
                     /locus_tag="VVR63_000359"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HEU6128414.1"
                     /translation="MKILVTSGGTSEAIDSVRSITNHSTGHLGKIITETLLSAGHEVC
                     LITTKRALKPEPHPNLSIREITNTKDLLIEMQERVQDYQVLIHSMAVSDYTPVYMTGL
                     EEVQASSNLKEFLSKQNHQAKISSTDEVQVLFLKKTPKIISLVKEWNPTIHLIGFKLL
                     IDVTEDHLVDIARKSLIKNQADLIIANDLTQISADQHRAIFVEKNQLQTVQTKEEIAE
                     LLLEKIQAYHS"
     gene            51118..52788
                     /locus_tag="VVR63_000360"
     CDS             51118..52788
                     /locus_tag="VVR63_000360"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HEU6128415.1"
                     /translation="MKTDIEIAQSIELKPIVDVVEKLGISYDDLELYGKYKAKLSFDK
                     IRAVESNPVGKLILVTAINPTPAGEGKSTLTIGLADALNKIGKKTMIAIREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLHQGNELGIDQRR
                     ILWKRVVDLNDRALRHVTVGLGGPLNGIPREDGFDITVASEIMAILCLATDIEDLKRR
                     LANIVIGYRYDRTPVSVGDLQVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATTTALHLADYTVTEAGFGADLGAEKFLDIKTPNLPTSPDAVVIVATLRAL
                     KMNGGVAKDALTEENVEAVRAGFANLKRHVENIRKFGIPAVVAINEFVSDTEAEIAVL
                     KELCASIDVPVELASVWADGAEGGVALAETVVKTIAENPANYKRLYDNDLSVQEKIEK
                     IVTEIYRGSKVNFEKKSQTQIAQIVQNGWDKLPICMAKTQYSFSDNPNALGAPENFEI
                     TIRELVPKLGAGFIVALTGDVMTMPGLPKRPAALNMDVESDGTVLGLF"
     gene            53116..54291
                     /gene="mutY"
                     /locus_tag="VVR63_000361"
     CDS             53116..54291
                     /gene="mutY"
                     /locus_tag="VVR63_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HEU6128416.1"
                     /translation="MLDLKEYGIVMWPEEKVISFREKLLAWYDENKRDLPWRRSKNPY
                     HIWVSEIMLQQTRVDTVIPYYERFLDWFPTVESLATASEESLLKAWEGLGYYSRVRNM
                     QAAAQQIMTDFGGQFPNTYEGISSLKGIGPYTAGAISSIAFNLPEPAVDGNVMRVLAR
                     LFEVNHDIGIPSNRKIFQAMMEILINPDRPGDFNQALMDLGSDIESPVNPRPEESPVK
                     DFSAAYQNGTMDRYPIKSPKKKPVPIYLKALVVKNSQGQFLLEKNESEKLLAGFWHFP
                     FIEVDNFSQEEQFDLFHQVAEESVNFGPSPEESFQQDYDLDVDWLDVCFDTVQHVFSH
                     RKWHVQIVAGQVSDFHDFSDREVRWLSPEEFKNYPLAKPQQKIWQAYAQANLDSSQD"
     gene            54346..55050
                     /locus_tag="VVR63_000362"
     CDS             54346..55050
                     /locus_tag="VVR63_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU6128417.1"
                     /translation="MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAE
                     QPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSAKDSEFDKVIGLELGADDYVTKP
                     FSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLT
                     HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPE
                     YILTRRGVGYYMRNNA"
     gene            55043..56392
                     /gene="vicK"
                     /locus_tag="VVR63_000363"
     CDS             55043..56392
                     /gene="vicK"
                     /locus_tag="VVR63_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HEU6128418.1"
                     /translation="MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQI
                     NQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSEVIRLTQENLEQESKRLNSILFY
                     MTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
                     LLLDSQDINGEYLNLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALCETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATS
                     HLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIWMEIDTDKMTQVVDN
                     ILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSR
                     AQGGTGLGLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED"
     gene            56394..57203
                     /locus_tag="VVR63_000364"
     CDS             56394..57203
                     /locus_tag="VVR63_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEU6128419.1"
                     /translation="MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLL
                     AEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMDLYANEKTWQAMENSKYLGKVDS
                     SQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
                     IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKK
                     IYLGHLSKENNIKELAHMTMVNQLAQADLGVGVDFKVYDTSPDTATPLTEI"
     gene            57294..57536
                     /locus_tag="VVR63_000365"
     CDS             57294..57536
                     /locus_tag="VVR63_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HEU6128420.1"
                     /translation="MTTITLKVSEADKTFMKAMAKFEGVSLSELIRTKTLEALEDEYD
                     ARVADLAYQEYLEDLEKGVEPITWEEMMHDLGLKDE"
     gene            57538..57792
                     /locus_tag="VVR63_000366"
     CDS             57538..57792
                     /locus_tag="VVR63_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEU6128421.1"
                     /translation="MYKLVPTRRFIKQLKKLDRYTQKLITNYLQTNVLEDPRRHGKAL
                     VGNRVGQWRYRIGNYRVIVQIVDDELVVATLEVGHRRDIY"
     gene            57839..58612
                     /locus_tag="VVR63_000367"
     CDS             57839..58612
                     /locus_tag="VVR63_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ion transporter"
                     /protein_id="HEU6128422.1"
                     /translation="MKKKWFFVDYYDTTIILLALISVILVLLGFAEMIDLDNPPYSII
                     DLVIWGVFVIDYSWRFFITKRKWRFILENIFDLLAILPLNAIFTVFRLGRIFRLAKLT
                     KLLKLTRLLRIIGLTGKLERKISRFLRTNGLIYILYVNIFIVLVGSSILSVVEEKSFS
                     DSLWWALVTVTTVGYGDIVPASIFGKWLAVLLMLVGIGTIGMLTSALTNFFVKDNPDE
                     QIKLDKLQDELSSQRILLEKQSKKIEELHKMIQDLIEKT"
BASE COUNT        18088 a        10471 c        12852 g        17363 t
ORIGIN      
        1 acaggtccat agagacttag tacgtgtttg acatactcgt aatggatttt atcatagttt
       61 cgccaagcag tgcgtgcttg attgtttagt tttaggctac ccagtccaat cagaggactg
      121 gtgggttggt aaaatttctc aagattaatt aagatactgt tgttcaactt ttctgttttt
      181 tgagctcttg catagtagtg tttagcagct cttgtagtcg aatatcatct gccgtaacct
      241 gtttacagtt ttggtagctt ttatttaact tggataggag ttgaatgagt ttcttgtctt
      301 ccatgtgagc atcctccttg atctgatgta ctctttccct atagtatagc actaaaaaat
      361 aaaactatca tagtaaatat gttaaaattt gaattttaat tacaaagttt ggtgtgctga
      421 tttgtagcct tttcatggta taatcaagag agtaaatctt tatggaggaa gtatgaaatt
      481 aaatattcaa gaaattcgta agcagtctga aggtttgaac tttgaacaaa cgttagattt
      541 agttgatgac ctgcgtgcac gtaatcaaga aattttagat gtaaaagata tccttgcagt
      601 tgggaaagta caatatgaag accgtatgta tttcttagat tatcaactat cttataccat
      661 tgttcttgct tcgagtcgca gtatggagcc agttgagtta gttgaatctt atccagtcac
      721 ggaagttttc atggaaggcg caactaacca gctagatcaa gaagttttag atgatgactt
      781 ggtcttgccc atcgaaaatg gggcgcttga ccttgctgag agtgtatcag acaatatcct
      841 gctaaacatt cctatcaagg tcttgacggc tgaagaagaa gctggtcaag gatttgtctc
      901 aggaaatgac tggcaaatca tgacagagga agaataccaa gctcaacaag cagtaaagaa
      961 agaagaaaac agtccttttg ctggcttaca aggactattt gacggagatg aataatggtc
     1021 ttgtcaaaaa aacgagcacg aaaggtgcta gaagaaatca ttgccctctt cccagatgcc
     1081 aagcctagtc ttgattttac caatcatttt gaactcctgg ttgcggtcat gttatcagcc
     1141 cagacgacag atgcagcggt aaataaggcc acaccaggtc tctttgttgc ctttccaaca
     1201 ccccaagcta tgtctgtagc gacagagagt gagattgctt cacatatttc tcgcttggga
     1261 ttgtatcgga ataaagctaa attccttaaa aaatgtgccc aacagttact agacgatttt
     1321 gatggtcaag tccctcagac acgtgaagaa ttggagagtt tggcaggtgt tggtcgcaag
     1381 acagccaatg ttgtcatgag tgtaggattt gggattccag cctttgcagt ggatactcat
     1441 gtggagcgta tttgcaaaca ccacgatatt gtcaaaaaat cagcgacgcc acttgaggtg
     1501 gaaaagcggg tcatggatat cttgccgcct gagcagtggt tagctgccca tcaggccatg
     1561 atttattttg gaagagccat ttgccatcca aaaaatccag agtgtgacca gtacccataa
     1621 ttatatgatt ttagcaattt gtaagatgct acattgaaac tttttgcttg attttaagca
     1681 tgctttgtgc tatagtaaat gataactaaa tattccttta aacctgtccc gtgaggcagg
     1741 caaggagcgc gataaagtag aagggtgaag tctacactgt gtgcagtagg gctcgcttgg
     1801 ctataaattt caagtctcct tgtttaagga gacttttctt tttggaggtt tgtcatgaaa
     1861 acaaaagaag ttgtagacga attgaccgtc aaacgagcga ttacgcgtat tacttatgag
     1921 attatcgaac gcaacaaaga tttgaataag atcgtcttgg ctggtattaa aactcgtggt
     1981 gtctttattg cccaccgaat ccaagaacgt ttgaagcagt tagaaaatct ttcagttcct
     2041 gttgtggaat tggatactaa acctttccgt gatgatgtta aaagtggaga agatacttct
     2101 ttggtttctg tcgatgtgac agaccgcgaa gttatcttgg tggatgatgt gctctataca
     2161 ggtcgtacca tccgtgctgc tattgataat attgtcggtc atggtcgtcc tgcgcgtgtg
     2221 agtttagcag ttctagtcga tcgtggacat agagaattgc caatccgtcc agattacgtt
     2281 ggaaaaaata tcccaaccag tcgttctgaa gaaatcatcg tagagatgac agaacttgat
     2341 gaccaagaca gagttctgat tactgaagaa gcttagaaag ttaaaggagt agccatgtca
     2401 gaaaatcaac aagcattgaa ccatgtggtg tccatggaag acctcactgt cgatcaagta
     2461 atgaaattga tcaagcgagg aattgagttt aaaaatggag cccagcttcc ctatgaagac
     2521 catccgattg tttccaatct cttctttgag gattctacac ggacacataa gtcctttgaa
     2581 gtcgcagaga ttaaacttgg attggaacga cttgactttg atgtgaagac tagttcggtt
     2641 aataagggtg agacacttta tgacaccatt ttgactctgt ctgctttagg agtggatgtc
     2701 tgtgtgattc gccatccaga ggtcgactac tatagagaat tgattgctag tccaacgatt
     2761 acgacttcca tcatcaatgg tggagatggt tcgggccaac accctagcca gagcttgctt
     2821 gatttgatga ccatttatga ggaatttggc cactttgagg gtcttaaagt tgctattgca
     2881 ggtgacttgg atcactcacg cgttgccaaa tccaatatgc agattttgaa acgcttggga
     2941 gctgaactct ttttcgctgg acctgaggaa tggagaagtc aagagtttgc agactatgga
     3001 cagtttgtaa ccattgatga aatcattgat caggttgatg tcatgatgtt tctccgtgtg
     3061 caacacgaac gccatgatag tggagctgta ttttcaaaag aagactacca tgcccaacat
     3121 ggcttgactc aagaacgtta cgatcgtttg aaagaaacag caatcctcat gcacccagct
     3181 ccaatcaatc gtgatgtaga aatagcagac cacttggttg aagcaccaaa atcacggatt
     3241 gtccaacaaa tgaccaatgg tgtctttgtt cgaatggcaa tcttagaatc cgtactagcg
     3301 agtagaaacg ccaactaaaa cacaagacgt taaaagacgc cagtgagcgt ccacgagagg
     3361 tgaaaatatg acaaaaagaa ttctagtatt agaagatggc acagtttttg aaggcaaggc
     3421 cttcggagca gatattgatg taacaggcga aatcgtcttt aatacaggga tgaccggcta
     3481 ccaagaatcc attacagacc agtcttataa tggacaaatc ttgaccttta cttatccttt
     3541 ggtaggaaat tatggtatta atcgtgatga ttatgaatcc attattccaa cttgtaaggg
     3601 agtcgttgtt tttgaagaag cgcgtagagc tagcaactgg cgcaaccaaa tgaccttgga
     3661 tgaatttttg aaagccaaga aaattccagg gatttcagga attgatacgc gtgctcttac
     3721 caagattatc cgtaagcatg gtactatgcg tgcaaccttg acccatgttg gggacagtat
     3781 ggaccatgtg acggaccagc tccaagcaac agttttaccg acagacaata tcaaacaggt
     3841 ttctactaaa acgtcttatc cagctccagg agttggtttg agcgtggtgc tagtggactt
     3901 tggtctcaag cactcaatcc tacgtgaact ttctaaacgc aactgtaacg tgacagttgt
     3961 tccttattcg acaacggctg aagaaattct ccatctcaat cctgatggag ttatgttgtc
     4021 aaatggtcca ggtaacccag aagacgttcc acaagcactc gacatgattc gcggtgtaca
     4081 aggaaaaatt ccaatctttg gtatttgtat gggacaccaa ctctttgcaa tggcaaacgg
     4141 ggctaagacc tataagatga agtttggcca tcgtggattc aaccatgcgg tacgtgaaat
     4201 cgcaacagga cgagtagact tcaccagcca gaaccatggt tatgcagtca gccgcgagga
     4261 tttgccagag cacttgatta ttacccacga agaaatcaat gacaagtcag tggaaggtgt
     4321 gcgccacaga taccaacctg ctttctctgt tcaataccac ccagatgcag ctcctgggcc
     4381 acacgacgct agctacctat ttgacgagtt tatcgagatg atggaagttt ttaaacaatc
     4441 aaactaagaa cgagtaaaag ctcgtcggag aatttatgta actgaacacg gacggaaagc
     4501 tcagaattta gagaaaccaa cttggattgt caatccttcc ttgatttctt aaaattcaat
     4561 cgctttctat tcgtcctttg tatcttattt aatgtcgccc tgagaggcga cgaatagaaa
     4621 ggagaagata cattgttcgc ggaagtgaac acgccctaag aactgtgtga aaaagataaa
     4681 catcgtcttg acgctgaagg cgtctgcgcc gagtttccta ttttcactgt gttctttacg
     4741 ggctttgtat cataaactat gcctaaacgt actgatattc aaaaaattat ggtgattggt
     4801 tctggtccga ttattattgg tcaggctgct gagtttgact acgctgggac tcaggcttgc
     4861 ttgtcgttga aagaggaagg ttatgaggtt gttttggtta actcaaatcc tgcaaccatc
     4921 atgacggaca aggaaattgc tgacaaggtt tacattgaac cgattacact tgagtttgtg
     4981 acacgtattc ttcgtaagga aggtccagat gccttgctac caacactcgg tggtcagaca
     5041 ggtctcaaca tggccatgga attatctaaa aatggtatcc tagacgagct tggcgttgaa
     5101 cttctgggta ccaaattatc tgccattgac caagcggagg accgtgatct ctttaaacaa
     5161 ttgatggaag agcttgaaca acccattcca gaatctgaaa ttgttaacac agtagaagaa
     5221 gcagttgcct ttgcagcgac aattggctac ccagtcatcg ttcgtccagc ctttaccctt
     5281 ggtggtactg gtggtggtat gtgtgccaac gagaaagaat tgcgtgaaat cactgaaaat
     5341 ggtttgaaat tgtcacctgt tacccaatgt ttgattgagc gttcgattgc cggtttcaag
     5401 gaaattgaat acgaagtgat gcgtgactca gctgacaatg ccttggttgt ttgtaacatg
     5461 gaaaactttg acccagttgg gattcacaca ggggattcca ttgtatttgc ccctgcgcaa
     5521 accatgtcag actatgaaaa ccaaatgctt cgtgatgcga gcttgagcat tattcgtgcc
     5581 ctcaagattg aaggtggatg taatgttcag ctagctcttg atcctaacag cttcaagtat
     5641 tatgttatcg aagtaaaccc tcgtgtatca cgttcgtcag cccttgcttc taaagcgaca
     5701 ggatatccga ttgctaagtt ggctgccaag attgcagtag gtttgacctt ggatgaggtt
     5761 ataaacccag ttacaggttc aacctatgcc atgtttgaac cagcccttga ctacgtagtt
     5821 gctaagattc cacgtttccc atttgacaag tttgaaaagg gtgaacgccg tctcggtaca
     5881 caaatgaagg cgactggaga agtcatggca atcggtcgta acatcgagga atctcttctc
     5941 aaggcctgcc gctcccttga aattggggtg caccacaatg aaatacctga acttgcagca
     6001 gtttctgatg ataccttgat tgaaaaggtt gtcaaagccc aagatgaccg tctcttctac
     6061 gtatcagaag ccattcgtcg tggctacaca cctgaagaaa ttgcagagct tacaaaaatt
     6121 gatatcttct atcttgataa actcttgcat atctttgaaa ttgagcaaga attgggtgct
     6181 catccacaag atctagaagt tttgaaaaca gccaaactta atggtttttc agaccgtaag
     6241 attgctgaac tctggggaac gactgatgat aaagttcgcc aacttcgctt ggaaaacaag
     6301 attgttccag tttataagat ggtagacact tgtgcggcag agttcgattc cgaaacgcca
     6361 tatttctatt caacctatgg ttgggaaaat gaatctatca aatctgataa agaatctgta
     6421 cttgtcctag gttcaggtcc aatccgtatc ggtcaagggg ttgagtttga ctacgcaacc
     6481 gttcactctg ttaaggctat ccaggcagct ggttatgaag ctatcatcat gaactcaaac
     6541 ccagagaccg tttcaacaga cttctctgta tcagataagc tttactttga gccattgaca
     6601 ttcgaagatg ttatgaacgt cattgacttg gaacaaccaa agggagttat cgttcagttc
     6661 ggtggtcaaa cagccatcaa ccttgcagag ccattggcaa aagcaggtgt gaccatcctt
     6721 ggtacacagg ttgctgacct agaccgtgcc gaagaccgtg acctcttcga gcaagctctc
     6781 aaagaattgg atattccaca gccaccagga caaacggcta ccaatgaaga agaagcagct
     6841 cttgcagctc gtaagattgg cttcccagtt cttgtccgcc catcttatgt acttggtgga
     6901 cgtgccatgg aaatcgttga aaacgaagaa gaccttcgtt cttacatgcg aactgctgtt
     6961 aaggctagtc cagaccatcc agttcttgtc gactcttata tcgttgggca agagtgcgaa
     7021 gttgatgcca tttcagatgg taaaaatgta ctcattcctg gtatcatgga gcatatcgaa
     7081 cgtgctggtg tccactcagg tgactcaatg gctgtttacc caccacaaac cttgtcgcaa
     7141 aaggttcagg agaccatcgc agactacacc aaacgcttag caatcggtct tcactgcctt
     7201 ggaatgatga acatccagtt tgttatcaag gatgaaaaag tctacgttat tgaggtcaat
     7261 ccacgtgcca gccgtaccgt tccattccta tctaaggtaa ccaatattcc tatggctcaa
     7321 gtagcgacca agctcattct tggtcaaagt ttatcagaac ttggctacca aaatggactt
     7381 taccctgaaa gcacccgtgt tcatatcaag gcacctgtct tctcctttac caaactagct
     7441 aaggtagaca gcttgctcgg tcctgaaatg aagtcaacag gtgaagttat gggttctgat
     7501 gctactttgg aaaaagctct ctataaagcc tttgaagctt cttatctaca cttgccaact
     7561 tttggtaatg tcgtctttac catcgctgat gatgccaaag aagaagcctt gaacttggct
     7621 cgtcgtttcc aaaacattgg ttatggaatc cttgcgacag aagggacagc agccttcttt
     7681 gctagtcatg gcttgcaagc ccaacctgtt ggtaagattg gtgatgacga taaggatatc
     7741 ccaagttttg tacgcaaagg aagaattcaa gctatcatta acacagtagg aacaaaacga
     7801 actgctgacg aagatggtga gcaaattcgt cgttcagcca ttgaacacgg ggtgcccctc
     7861 ttcacagcgc tagatacagc taatgccatg cttaaggtac ttgaaagtcg tagctttgtt
     7921 acagaagcga tttaaataga aaaataagat atagcagact gaatttagaa cagtacacag
     7981 ggatactaaa atatttctag aaattaattt gaattttcta attgatttgt tcgcatctta
     8041 tttcaatcta ctatagaaaa aagtctttaa aattataaaa cgcatcatat caaggttttt
     8101 caaaaacctt gatatgatgc gttttattgt gggaatatat atttcatttt ctactaaaat
     8161 tatgtttttg aataacctct atcttagtag tttgtataat ccccctcaat cagtttttgc
     8221 gataagcttt aatgctatga ctataccact cttgcatttc ttttgatggt ggtgtcatat
     8281 aatcgccata catctgggtt aaaaattggt catatttttt gggaacaggc aacatacggc
     8341 cctcaaactc agttaaaatc agttctttaa aggtatcaac tgggaagatt tctttcatcc
     8401 cttccttacc gatcccaact cctccttcat attgaggagt gttggttaca gcatttttga
     8461 ctagttgatc aattttcttg taaaagtagc gaggattgac aaatcggaga gcgtaccagc
     8521 tacataatct aagaaaatct tttagtttgc tatcaccgtg aactgctcgt gattttttga
     8581 tataagctag ttgacgaagg gccacatact tatagctctt gtcgacaatg ctcaagtctg
     8641 taaatcgatc aattgggaag acatcgatga aaaggctggt atcatgacgc ttgtacttaa
     8701 catggtcttc tataacagta gaagtgtcca aaatcgatgc gaaattatgg aagtaccaag
     8761 aagatgtatc gtaggaaaga accttgtagc gagggtgatt ttcttcttca ataatcttca
     8821 gtaaacgctc ataatcctca cgataaaggg aaatatcaat atcatcatcc caaggaatca
     8881 tacctttgtg gcggatggct ccaagcatgg ttccataact gagaaaataa ggaatatcat
     8941 gtttcttaca agtctcatca atatagtcca gcagggctag ttgaatttct ttaatttctt
     9001 ttttttctaa atattgcatc ctaatcctcc aatttataag cgtgaaattc atgactgtag
     9061 aagcgttttt cttctggtgg tagggtcata taatctccat aaaattgtgt caaaatagta
     9121 tcaaattttt caggtgcagg aaggcttaaa ttctcaaagg gtaaatcgat tgttttatca
     9181 aaggtaccac ttgggaagac ttccttttcc ttaaattttg aaggaataaa agccatatac
     9241 tgcccatttt cacgactata tttttgaatt tctttctcga ttttatttgc aaaataacga
     9301 ggagaaaccg gtcgaaggag caaccaaaag gctgttcgta tccaatcttt taaaaggcta
     9361 tccttataga caatattttt atgtttactg aaagacagca gtttgaagct ttccagttta
     9421 taacaagtat caatgacctt aggatcatca aagcgatcta tagggaaaat atcgataaag
     9481 ataccagact cataggtttt tgtatttcga gtatcaataa ttttagtcgt actgtcggtt
     9541 atcttgataa agttgttaaa gtagttctta tcagtttcta aggataggag cttatacttg
     9601 cttttttcct tttgaaaaat gttaataaat cgttggtagt cttctctagg catggataaa
     9661 tcaatatcgt cgtcccaagg gataaagccc tcatgtcgaa ccgccccaat cagagtaccg
     9721 tagttaataa tatagttgat attgtgcttt ttacagagag tatcaatata atccaaaatt
     9781 tctaattcaa tttgtttggc atcttcaatg gttagttgtt tcattttaaa ctcctatgat
     9841 tttttgaatt tattttttaa ggctaggaca tggtttaaaa attcatagaa aatgctatct
     9901 tttgtgaaga caagtagact aatataagag atagctgata gcaagacaat caaaccagta
     9961 ttaattaaaa atggcaaatt aatgaccata tccacaggat acacgaaatt aatcaggaaa
    10021 taaattgcta caaaggaaag tgaaaagaga gagtatcgaa cagtatagct aaagatatgt
    10081 cccaagtgga tgagttgttt tctatggatg aaaataatat agaaaacaag tagagaagtc
    10141 tctgataaca tagttgtcag taagtagtat tcaggaacca cgatatggtt gaaaaagagg
    10201 agactattca agcccaaatt gagtagccca gcaaagactg tatagactgt gatacgtttt
    10261 tcatagccat tggtaaagag aatttgggaa ccaagaatgg tatctaaggc caggataatc
    10321 gtacgaaaag cgaagagaga ggtcaagatg ccgcctccga tatatttttc actaccgtaa
    10381 agtaggatgg catttggtcc taaaaccatg agtccaaaac tcagtggaat gataaagaag
    10441 ttaaagattc gactacctct attaaccaga gaaacatagg cttctttgtc tcctttcccc
    10501 agatagtaac tgagacgagg cacactcact ccaattgcac ctgttacaac cccagctata
    10561 acggtcacaa ttcgctgagc tatggtatag taactaacgt tgacatcaat ccctgtttta
    10621 acgaggaaga ggcgatctaa aaaagtgaag agcatattgg cattggcaaa gactaacatg
    10681 gctgtcagag ggagaaagag tggtttaaaa tcacttaggt gaatcttaac aagtttgatg
    10741 tctcttttaa tccaaaaata actaatcagg tagttaatca gcgtcgataa actcatcaca
    10801 agtgtataga caacaatatc gtgttcattt ttaacaaata agaaaataga gaccagcatc
    10861 aggatacgga tgaaggcagt tttgtaaaag agaaaactgt aattttccag agcttcattg
    10921 acccattcga ttgaaaaaat ctgggcaatg agttgaatcc ccataacaag gtagaccttt
    10981 ttgacgattg gattatcaat aaagaagaga ggataggcta ggatatagac agcagtggtc
    11041 aaaatcgtac aagcgatgca caaataaaaa agactagaaa aggttctgtt aagatctttt
    11101 ttgttatcct tgacattact gatagccctt aaaccgtagt tatagacacc ataagttgca
    11161 aagggcaaga aaaatgacaa aatagtgtcg actgagttga agtaaccata gtcagttcgg
    11221 tccaagacac gcgcgacata ggttccagtt aggatgggaa aaataatatt caagacacga
    11281 attcccatgt aagatagagc atttaatttt atacttttca ttcaatttac ctcgtttttc
    11341 attatatcat aaagttagct aataagaaat gaagggcagt aagtcaagta atcactttga
    11401 agtttcaaat cttaagtttt aagttttctt taaggaaagt atattattct gaaggactct
    11461 aaaatttcgc agccatttat tagtaattgc tacagaattc ctagtcatta ctagaaatgg
    11521 actagtttct ttgaataata gaactgcata attctcctat tctagaaggg gaggaccagt
    11581 atttctttta tgataggact agattgtggt ataatagaga gaataagttt ttttagtaag
    11641 acaaaggaga aaatagatga tttatgcagg aattcttgcc ggtggaactg gcacacgcat
    11701 ggggatcagt aacttgccaa aacaattttt agagctaggt aatcgaccta ttttgattca
    11761 tacaattgaa aaatttgtct tggagccaag tattgaaaaa attgtagttg gtgttcatgg
    11821 agactgggtt tctcatgcag aagatcttgt agataaatat cttcctcttt ataaggaacg
    11881 tatcatcatt acaaagggtg gtgctgaccg caatacaagt attaagaaaa tcattgaagc
    11941 cattgatgct tatcgtccgc ttactccaga ggatatcgtt gttacccacg attctgttcg
    12001 tccatttatt acacttcgca tgattcagga caatatccaa cttgcccaaa atcatgacgc
    12061 agtggacaca gtggtagaag cggttgatac tatcgttgaa agtaccaatg gtcaatttat
    12121 tacagatatt ccaaatcgtg ctcaccttta tcaaggacaa acacctcaaa cattccgttg
    12181 caaggacttc atggaccttt atggatctct ttctgatgaa gagaaggaaa tcttgacaga
    12241 tgcatgtaaa atctttgtga tcaaaggaaa agatgtggcc ttggccaaag gtgaatactc
    12301 aaatctgaag attacaaccg taacagattt gaagattgca aaaagtatga ttgagaaaga
    12361 ctagtaaaat gattaatcaa atttatcaac taactaagcc taagtttatc aatgtcaaat
    12421 atcaggaaga ggctattgac caagagaatc atatccttat ccgtcccaac tacatggctg
    12481 tctgtcatgc ggatcagcgt tactatcagg gaaaacgtga tcccaagatt ttgaataaaa
    12541 agcttccaat ggcaatgatt cacgagtcat gtggaaccgt catttctgac ccgaccggaa
    12601 cctacgaggt tggtcaaaaa gttgtcatga ttcccaatca gtctcctatg cagagtgatg
    12661 aagaattcta tgaaaactac atgacaggga cccatttctt gtctagtgga tttgatggct
    12721 ttatgagaga gtttgtttct ctccctaaag atcgtgtggt ggcttatgat gctattgaag
    12781 atacggttgc agccattaca gagtttgtca gtgtgggcat gcacgctatg aatcgtctat
    12841 tgactcttgc tcatagcaag cgggagcgga tcgccgttat tggagatgga agtttagctt
    12901 ttgtggttgc caatattatc aactatactt tgccagaatc agagattgtg gttattggtc
    12961 gtcattggga aaagttggaa ctcttctcat ttgccaaaga atgctatatt acggataata
    13021 ttcctgaaga gttggccttt gaccatgctt ttgaatgttg tggtggtgat ggtactggac
    13081 cagctattaa tgacttgatt cgctacattc gtcctcaggg aacgattctc atgatgggag
    13141 ttagcgaata taaagtcaat ctcaatactc gcgatgcctt agaaaagggc ttgattttgg
    13201 ttgggtcatc tcgttctggt cgcattgatt ttaaaaatgc tatccaaatg atggaagtca
    13261 agaaatttgc caatcgtctt aaaaatatcc tttatctaga agaacctgta agagaaatta
    13321 aagatattca tcgtgtcttt gcaaccgatt taaacacagc ctttaaaaca gtgtttaagt
    13381 gggaagtata agtactggag gttaattgtg gagaaaatca ttaaagaaaa aatttcttcc
    13441 ttacttagtc aagaagagga agtcctcagt gttgaacaac tgggtggaat gaccaatcaa
    13501 aactatttgg ccaaaacaac aaataagcaa tacattgtta aattctttgg taaagggaca
    13561 gaaaagctta tcaatcgaca agatgaaaag tacaatcttg aactactaaa ggatttaggc
    13621 ttagatgtaa aaaattatct ttttgatatt gaagctggta tcaaagtaaa tgagtatatc
    13681 gaatctgcga ttacgcttga ttcaacgtca atcaagacca agttcgacaa aattgctcca
    13741 atattacaaa ctattcatac gtctgctaag gaattaagag gagaatttgc tccttttgaa
    13801 gaaatcaaaa aatacgaatc cttgattgaa gaacaaattc cttatgccaa ctatgaatct
    13861 gttagaaatg cagtcttctc cttagagaaa agactggctg acttaggtgt tgacagaaaa
    13921 tcttgtcata tcgatttggt gcctgaaaac tttatcgaat cacctcaagg acgactttat
    13981 ttgattgact gggaatattc atcaatgaat gatccaatgt gggatttggc tgccctcttt
    14041 ttagagtctg aattcacttc ccaagaggaa gaaactttct tatctcacta tgagagtgac
    14101 caaacaccgg tttctcatga aaagattgct atttataaaa ttttacaaga tactatttgg
    14161 agtctatgga ctgtctataa ggaagagcaa ggtgaagatt ttggtgacta tggtgtgaat
    14221 cgttaccaaa gagctgttaa aggtttggct tcttatggag gttcagatga aaagtaaaaa
    14281 cggagttcct tttggccttc tctcaggtat tttctggggc ttgggtctaa cggttagtgc
    14341 ttatatcttt tcgattttta cagatttgtc accctttgtg gtggctgcag ctcatgattt
    14401 tttgagcatc tttatcttac tagcttttct cttggtaaaa gaagggaaag ttcgcctctc
    14461 aattttctta aatattcgca atgtcagtgt tatcatcgga gccttgctag caggccctat
    14521 cggtatgcag gccaatcttt atgcagttaa gtatatcgga agttctttag cttcatctgt
    14581 atcggctatt taccctgcga tttcagttct attggctttc ttctttttga agcacaagat
    14641 ttcgaaaaat actgtatttg ggattgtctt gattattgga gggattattg cccagaccta
    14701 taaggttgaa caggttaatt ccttctacat tgggattctc tgtgctttgg tttgtgctat
    14761 tgcatgggga agtgagagtg ttcttagctc ctttgctatg gaaagtgaac tgagtgaaat
    14821 cgaagccctc ttaatccgtc aagtgacttc gttcttgtcc tatcttgtga ttgtgctctt
    14881 ctctcatcag tcatttactg cagtagccaa tggacaattg ctaggtctca tgattgtttt
    14941 tgcagccttt gatatgattt cctacttggc ttattatatc gctatcaatc gcttgcaacc
    15001 agccaaggct acaggcttga acgtgagcta tgtagtatgg acggtcttgt ttgcagttgt
    15061 ttttttgggt gcaccgctag atatgctgac cattatgacg tcacttgtcg tcattgctgg
    15121 agtttatatt attattaaag aataaaggag attcgtgtga aagccattat cttagcagcg
    15181 ggattgggaa ctcgcttgcg tcctatgact gaaaataccc ctaaagcctt ggttcaggtt
    15241 aatcaaaaac ctttgattga ataccaaatt gagtttctca aagaaaaagg aatcaatgac
    15301 atcatcatca ttgttggtta tcttaaagaa caattcgatt acttaaaaga aaaatacggt
    15361 gttcgcctcg ttttcaatga taaatacgct gactacaata acttttactc tctctatctt
    15421 gtaaaagaag aattggccaa cagctatgtt attgatgctg acaattatct ctttaaaaat
    15481 atgttccgca atgatttgac acgttcgact tattttagtg tttatcgtga agattgtacc
    15541 aacgaatggt tcttggtcta tggagatgac tacaaggttc aagacattat tgttgatagc
    15601 aaggcaggtc gcatccttag tggtgtatcc ttctgggatg ctccaactgc agaaaagatt
    15661 gtcagcttta tcgacaaggc ttatgtaagt ggtgaatttg ttgatctcta ttgggacaat
    15721 atggttaagg ataatatcaa agagctagat gtctatgttg aagaattaga aggcaatagc
    15781 atttatgaga tcgatagtgt ccaagactat cgtaaattag aagaaattct taaaaacgaa
    15841 aattaaagat tccaacatct gacaaaatag tcggatgttt tttgattttt tacgaacttt
    15901 tacgaataga tagatgagta gaaaaagaaa tggagttatt tatgaaaatc acaaactatg
    15961 aaatctataa gttaaaaaaa tcaggtttga ccaatcaaca gattttgaaa gtgctagaat
    16021 acggtgaaaa tgttgatcag gagcttttgt tgggtgatat tgcagatatc tcaggttgcc
    16081 gtaatccagc cgtttttatg gaacgttatt ttcagataga cgatgcgcat ttgtcgaaag
    16141 agtttcaaaa atttccatct ttctctattt tagatgactg ttatccttgg gatttgagtg
    16201 aaatatatga tgcgcctgta cttttatttt acaagggaaa tcttgacctc ctgaaattcc
    16261 cgaaggtagc ggtcgtgggc agtcgtgctt gtagcaaaca gggagctaag tcagttgaaa
    16321 aagtcattca aggcttggaa aatgaactgg ttattgtcag tggtctggcc aagggcattg
    16381 acacagcagc tcatatggca gctcttcaga atggcggaaa aaccattgca gtgattggaa
    16441 caggactgga tgtgttttat cctaaagcca ataaacgctt gcaagactac atcggcaatg
    16501 accatctggt tctaagtgaa tatggacctg gtgaacaacc tctgaaattt cattttcctg
    16561 cccgtaatcg catcattgct ggactttgtc gtggtgtgat tgtagcagag gctaagatgc
    16621 gttcaggtag tctcattacg tgtgagcgag caatggaaga aggacgcgat gtctttgcta
    16681 ttcctggtag cattttagat ggactatcag acggttgcca tcatttgatt caagaaggag
    16741 caaaattagt caccagtggg caagatgttc ttgcggaatt tgaattttaa aaatgaccta
    16801 agctagaatt ctaagaaaaa atcaatttta agagaaaatg aacccaacat ttccataata
    16861 aaacgcatat tagcaagttt ttaacacttg ataatatgcg ttttttctaa gtggattagt
    16921 agagtagagg atttttctca tataatactc ttcgaaaatc tcttcaaact acgtcagctt
    16981 ccatctgcaa cctcaaaaca gtattttgag ctgacttcgt cagtcttatc tacaacctca
    17041 aagcagtgct ttgagcaacc tgtggctagc ttcctagttt gcgctttgat tttcattgag
    17101 tataagggaa agtatagtga attgaaataa gatgtgaaca actctatcag gaaagtcaaa
    17161 ttgatttata gaaatatttt agcagccaag gtgcactgtt atagattcaa tacactataa
    17221 tttagtgtaa ttgagaaagg agaaatgatt gtgattgatg ttggctaggt tatgttcaat
    17281 gattcctacc gtctcaaatc ttgtcagtaa ggaaaaataa attcttcaaa agtagagatt
    17341 acaaggcttg tttaagaaag aattcaaaga ccttgacaaa taaaaataaa atggttatta
    17401 taaaaaatgg tctgaaatag atgatgatac ttttcgaaaa tctcttcaaa ctacgtcagc
    17461 tcagctttgc cttgctgtgt tttgagcaag ctacggttag cttccgagtt tgattttcat
    17521 ttactagaaa tgaaactgat gagagatatc agtagacatt tgagtcagga tattatggaa
    17581 aatgataaaa agagctcgtg agattggcat atcagactac taaagtattg agtttgttag
    17641 gattttagcg actagttagc tgggaaagga agatatttgt gacaaataat aaactgtatt
    17701 cgttgataga atttagaaat aaaatatatg aagaattaga actttccaga agtgatttag
    17761 cgattttact atgtgccatg cttatcgcct ctatcggatt aaatatggat tcgactcccg
    17821 tgattattgg agccatgtta atctctcctt tgatgacacc tattctggga gtggggctct
    17881 ctctagctat atttgatttt aaattgttaa gaaaatcttt taaaatatta gctattcaaa
    17941 ttcttgccag tctaatagct tcaacacttt atttttatct ttctcccatt tcgtatgcta
    18001 gttcggagat tgttgctaga acctctccga ctatttggga tgttctcatt gcttttgtag
    18061 gagggatagc aggtattatt ggtgctagga aaaaagagac caataatatt gttcctggtg
    18121 ttgctattgc aaccgccttg atgcctcctc tttgtacagt aggttatgct attgcttctg
    18181 ctaatctaaa atttatcata ggctcctctt acctattcct catcaattgt agctttattg
    18241 tcattgcgac ttatataggt gttaggttga tgatggttaa gaaacattat tttaaagata
    18301 atgaagaaga ctctaaaatg cgtaggattt tgcttctagt tgctgttttg ctgatgattc
    18361 cgagtttcat ctctgcaacg actttagtga gagaaacgtt gaaaaaagag tcccttaaga
    18421 aatttatatc agagcagttt caggggtata atattttgaa aaaaacctat tctaaaaaga
    18481 ctcataccct aaagctaacc atttcaggaa attatttgac agaagaagaa ctcgatatga
    18541 tttcaagtaa gagaggtgac tatggtttaa gtgatgtttc tgttcaagtt tcacaattgt
    18601 ctgattcaga acaacttagt aaggaagagc tggtggagta tttcttccag tatatcaagg
    18661 ataaggaagc aaaagaaaag gagaaagcca ataaatttga tacagagtct gaggagcaat
    18721 aatttcttga gaatagctgg tttctctcgt gagtcttcta tgtatatcaa aggaagactg
    18781 aggttttaag tataaaactt ttcttctatt atagtagcta agtcttgaca gggttcaaaa
    18841 aatggtttac actttataaa gtttattact ttgaaaaggt gtgatactgt ggctacggca
    18901 acaaaaaaga aaaaatcaac agttaaaaaa aatctagtca tcgtggagtc gcctgctaag
    18961 gccaagacga ttgaaaaata tctaggcaga aactacaagg ttttagccag tgtcgggcat
    19021 atccgtgatt tgaagaaatc cagtatgtcc gtcgatattg aaaataatta tgaaccgcaa
    19081 tatattaata tccgaggaaa aggccctctt atcaatgact tgaaaaaaga agctaaaaaa
    19141 gctaataaag tttttctcgc gagtgacccg gaccgtgaag gagaagcgat ttcttggcat
    19201 ttggcccata ttctcaactt ggatgaaaat gatgccaacc gtgtggtctt caatgaaatc
    19261 accaaggatg cagtcaaaaa tgcttttaaa gaacctcgta agatcgatat ggacttggtc
    19321 gatgcccaac aagctcgtcg gatcttggat cgcttggtag ggtattcgat ttcgcctatt
    19381 ttgtggaaga aggtcaagaa gggcttgtca gcaggtcgcg ttcagtccat tgcccttaaa
    19441 ctcatcattg accgtgaaaa tgaaatcaat gccttccagc cagaagaata ctggacagtt
    19501 gatgctgtct ttaaaaaggg aaccaaacaa tttcatgctt ccttctatgg agtagatggt
    19561 aaaaagatga aactgaccag caataacgaa gtcaaggaag tcttgtctcg tctgacgagt
    19621 aaagactttt cagtagatca ggtggataag aaagagcgca agcgcaatgc tcctttaccc
    19681 tataccactt catctatgca gatggatgct gccaataaaa tcaatttccg tactcgaaaa
    19741 accatgatgg ttgcccaaca gctctatgaa ggaattaata tcggttctgg tgttcaaggt
    19801 ttgattacct atatgcgtac cgattcgact cgtatcagtc ctgtagcgca aaatgaggcg
    19861 gcaagcttca ttacggatcg ttttggtagc aagtattcta agcacggtag caaggtcaaa
    19921 aacgcatcag gtgctcagga tgcccatgag gctattcgtc cgtcaagtgt ctttaataca
    19981 ccagaaagca tcgctaagta tctggacaag gatcagctta agctatatac ccttatctgg
    20041 aatcgttttg tggctagcca gatgacagcg gccgtttttg ataccatggc tgttaaattg
    20101 tctcaaaaag gggttcaatt tgctgccaat ggtagtcagg ttaagtttga tggttatctt
    20161 gccatttata atgattctga caagaataag atgttaccgg acatggttgt tggagatgtg
    20221 gtcaaacagg tcaatagcaa accagagcaa catttcaccc aaccgcctgc ccgttattct
    20281 gaagcaacac tgattaaaac cttagaggaa aatggggttg gacgtccatc aacctatgcg
    20341 ccaaccattg aaaccattca gaaacgttat tatgttcgcc tggcagccaa acgttttgaa
    20401 ccgacagagt tgggagaaat tgtcaataag ctcatcgttg aatatttccc agatatcgta
    20461 aacgtgacct tcacagctga aatggaaggt aaactggatg atgtcgaagt tggaaaagag
    20521 cagtggcgac gggtcattga tgccttttac aaaccattct ctaaagaagt tgccaaggct
    20581 gaagaagaaa tggaaaaaat ccagattaag gatgaaccag ctggatttga ctgtgaagtg
    20641 tgtggcagtc caatggtcat taaacttggt cgttttggta aattctacgc ttgtagcaat
    20701 ttcccagatt gccgtcatac ccaagcaatc gtgaaagaga ttggtgttga gtgtccaagc
    20761 tgtcatcagg gacaaattat tgagcgaaaa accaagcgta atcgcctctt ctatggttgc
    20821 aatcgctatc cagaatgtga atttacctct tgggacaagc ctgttggtcg tgactgtcca
    20881 aaatgtggca acttcctcat ggagaaaaaa gtccgtggtg gtggcaagca ggttgtttgt
    20941 agcaaaggcg actacgagga agaaaagatt aaataagagg aggggcccga aagtaaattt
    21001 caggctcctt ttggttagaa cttgacaaaa tacatcattt tatgcgaaac tagaagaaga
    21061 ttattttaac taggagaagt tatgcgtctt atctatctga taattggttt tttatcactg
    21121 gccttggcta ttgttggggt tgttttaccc ttgttgccta caacaccttt ccttttgttg
    21181 tctattgctt gtttctccag aagttccaag cgattcgaag actggcttta tcataccaag
    21241 ctctatcaaa catatgtagc tgattttcgc gagactaagt ctattacgcg tgaacgaaag
    21301 aaaaaaatca tcgtatccat ttacattttg atggggattt ctatttattt tgcccctctc
    21361 ttaccagtca aaatcggtct gggtgctttg accatcttta tcacttatta tctcttcaag
    21421 gtcattccag acaaagaata gttaaaacag tagttattta ccttgataaa attgaaagca
    21481 tattcataac aatatgatat aataaatttg aagtaatatt caaggagaat caaatgattt
    21541 acgaattttg tgctgaaaat gtgactttac ttgaaaaagc gatgcaggct ggagctcgtc
    21601 ggattgaact ctgtgataat ctagcagttg gtgggacaac acctagctat ggagtgacta
    21661 aggcagcggt tgaactggca gctaactacg atacaaccat catgaccatg attcggccac
    21721 gtggtggtga ctttgtctat aatgacctag aaattgctat catgctagaa gacatttgtt
    21781 tgactgctca ggctggaagt caaggggttg tatttggagc tttaactgct gataaaaagt
    21841 tggataagcc taatctggaa aagttaattg ctgcatcaaa aggaatggaa attgtctttc
    21901 acatggcctt tgatgaacta agtgatgaag atcaaccgga agctattgac tggctcagtc
    21961 aagccggtgt cactcgtatc ctaactcgtg ctggtgtgtc tggcgactcc ttagaaaaac
    22021 gttttgttca ctatcacaga attttggagt acgctaaagg taaaattgaa attctaccag
    22081 gtggggggat tgaccttgac aaccgtcaaa cctttattga ccaggtgggg gtaacacaat
    22141 tgcatggtac taaggttgtt ttttaaaaaa tagaaaggaa ctgctagcct tgggtagcag
    22201 ttttcactta tgtttgaaat ttttaaatcc tatcaattta atcaagaaaa ggctcatgat
    22261 tatggtttta tagaaaatag cgaagtctgg acatatagtt gccagatttt gcaaggtgac
    22321 tttgtcatga ctgtgtccat cactgctgat aatgtgaact ttcaagtctt tgaccaagag
    22381 actggtgacc tctatcctca cgttcatatg gaaagcatga ggggaagttt tgtcggaaat
    22441 gtccgtgagg cttgtctgga gattctttac cagattcgga aggcttgttt tgatgtgcaa
    22501 gattttatct gtcatcagac taagcgtatc atgactcaag ttcaggaaaa gtatggaaac
    22561 cagttggagt atctgtggga aaaatcgcct gatacagctg tattgcgcca tgaaggcaat
    22621 caaaagtggt atgccgtctt gatgaaaatc tcttggaata agctggaaaa gggcagagaa
    22681 ggacaagtgg aagcagtcaa cctcaagcat gaccaagtag ctaatttgct ttcacaaaag
    22741 gggatttatc cagccttcca tatgagcaag cgctactgga ttagtgtgtc ccttgatgat
    22801 actttatcag atgaagaagt actggaattg atagaaaaaa gttggaactt aacctctaaa
    22861 aaatgaaata ttttaataat tttcatgaac tttcaattag ctaaatattc tttactgaag
    22921 aaatttttag aaaatatagg atttaccaca ctagaggaat atggtgccat cttcaaatac
    22981 ctgattgaga atgtcaagac ggatcgtcag atcatctgtt cgcctcactg tcatgatgac
    23041 ctcggaatgg cagtggcaaa tagccttgct gctgtcaaga atggtgcagg acgtgttgaa
    23101 gggactatca atggtattag ggagcgagct gaaaatgctg ctttggaaga aattgcagtg
    23161 gctctcaata ttcgccaaga ttactaccaa gtagaaacca gtattgtcct aaatgagacc
    23221 atcaatacgt cagaaatggt ttctcgcttc tctggtattc cagttcctaa aaacaaagcc
    23281 gtcgttggtg gcaatacctt ctcccacgaa tctggtattc accaagatgg agtccttaaa
    23341 aatcctctca cttatgagat catcacacct gaattggttg gtgttaagat tccgcttgga
    23401 aaattatctg gtcgccatgc ttttgttgag aaactgagag aattggccct agattttaca
    23461 gaagaggata tcaaaccact ctttgctaag ttcaaggcac tggccgataa gaagtaagaa
    23521 atcacagatg cagatcctcg agctttggta gctggaacca tggttgaaaa tccagaaggc
    23581 ttccactttg atgatttaca acttcaaact catgcagata atgacattga agcgctcgtt
    23641 agcctagcca atatggatgg tgagaaagtc gaatttaatg cgacagggca aggttccgtt
    23701 gaagcaatct ttaacgctat cgataagttc tttaaccaat ctgttcgttt ggtgtcctac
    23761 actatcaatg cggtaacaga tggaatcgat gcccaggatc gggttttggt cactgttgaa
    23821 aacagagata cagaaaccat ctttaatgca gcagggcttg attttgatgt gttgaaggct
    23881 tctgctattg cctatataaa cgctaatacc tttgttcaaa aagagaatgc aggtgagatg
    23941 ggacgcagtg tttcttacca cgatatgcct agtgtgtaaa ggagaaggct atggcaaaga
    24001 aaatagtagc tctagtagga gacggaattg gcccagaaat catggaggct ggtttagaag
    24061 ttctggaggc tctagctgaa aaaacaggtt ttgactatga gattgacaga cgaccgttcg
    24121 gaggtgcaga tattgatgca gcaggacctc ccttacctga tgaaaccctt aaggcaagta
    24181 gggaagcaga tgctatccta ctagcagcta tcggtagtcc tcagtatgat ggagcagcgg
    24241 ttcgccctga acaaggcctg atggctctcc gtaaggaact caatctttac gctaatattc
    24301 gtcctgtaaa aatctttgac agtctcaagt atttgtcacc actcaaaccg gaacgaattt
    24361 ctggtgtaga ctttgtcgtg gtgcgtgaat tgacaggcga gatttacttt ggagatcata
    24421 ttcttgaaga gcgcaaagcg cgtgatatca acgactatag ctatgaggaa gtggagcgga
    24481 ttattcgcaa agcctttgaa attgcaagaa atcgcagaaa aatcgttact agtatcgata
    24541 agcaaaatgt tctagcgacc tcaaaactct ggcggaaagt agctgaggaa gtcgcacagg
    24601 atttcccaga tgtaaccttg gaacaccagc tggtagactc agctgctatg cttatgatta
    24661 ccaatcctgc taagtttgat gttattgtaa cggagaatct ttttggagat attttatctg
    24721 atgaatcaag cgtcttatct ggtacacttg aggttatgcc atcagccagt cattctgaaa
    24781 atggaccaag tctctatgaa cctattcacg gttcagcacc tgatattgca ggtcaaggaa
    24841 ttgccaatcc tacttccatg attttatcag ttgccatgat gttgagagat agtttcggac
    24901 gttatgagga tgcagagcgt atcaaacatg ctgttgagac aagtctggcg gcaggaattt
    24961 taacgagaga tataggaggt caggcttcaa caaaggaaat gacggaagct attattgcaa
    25021 ggttatgaag ttagacgaaa aaattactct agtccttttg atttggaatg tcatcatttt
    25081 cttgatttat ggcattgaca aattcaaggc aagaagaaga acttggcgca tccaagagaa
    25141 aatcttactc attttagccc ttacttgtgg tggttttggg gcctggttag ctggaatcac
    25201 ttttcaccac aagactcgaa aatggtactt taaaacagtt tggtttcttg ggatggtgac
    25261 cacactagta gccttatatt ttatttggag gtaatggatg gcagggtctt cgagggaaca
    25321 cgctgcttgg gttctagcgg actatggttt taaggtcgtg attgcaggat ctttcggtga
    25381 cattcattac aataatgaac tcaataatgg cctgttgcca atcgttcagc ctagagaggt
    25441 tagagagaaa ctagcccagc taaaaccaac cgaccaggta actgtggact tggaacaaca
    25501 aaaaatcatc tcaccagttg aagaattcac cttcgagata gatagcgagt ggaaacataa
    25561 actcctaaat agtttggatg atatcggtat taccttgcag tatgaagagt tgattgctgc
    25621 ttatgaaaaa caacgaccag cctactggca ggattagaaa aaatagaaaa ggaaatatag
    25681 taaactgaaa taagatgtaa acaaatgaat tagagcttaa catccatttc cagcaatttt
    25741 ttagaaacta cagtggacta ttctggattc aacacattat aaaattatga caaaacacat
    25801 tcacaagaag gctacgacat tttaaaaggt gagggcggat gtatcgtttg ccctactaaa
    25861 gttggttaca ttatcatgac cagcaacaag gcaggacttg agcgtaagtt cgcagccaaa
    25921 gaacgtaagc gtaacaaacc aggtgttgtt ctctgcggta gcatggatga acttcgcgct
    25981 ttagcgcaac tcaacccaga aattgaagca ttctactaaa aacattggat gaagatattc
    26041 ttcttggttg tatccttcct tggaaaccag aagcctttga aaaactcaaa gcatacggga
    26101 atggccgtga agaacttatg actgatgtac gtggtactag ctgttttgtt atcaagtttg
    26161 gaaaagcagg tgaacaattg gctgccaagc tttgggaaga aggtaaaatg gtctacgcct
    26221 catctgcttc aatgacaaaa cgattgaaac tcgctatgag caaggtgtaa tggtgtctat
    26281 ggtcgataag gacggcaaac tcatcccaga acaaggagga gcacgttcaa cttcaccagc
    26341 tccagttgtg atccgtaaag ggcttgacat tgataaaatc atgatgcacc tgtcagatac
    26401 ttttaactca tgggactacc gtcaggttga gtattattag gatagagaag aagtctagtg
    26461 ttatgagata ttaaagctcc taacactggg cttttgttta gaatttcttt tctttttcta
    26521 taggatatgg tattctatgt agaaaatata tgttaataag taatgccaat atttaaacat
    26581 cattagtaaa aggagttaga ttgatgaata aaagaaaagt tagtttagaa gatttttata
    26641 aatggtatag tctaaataaa gaagagttat taaataaggc aactgttggt gaaaagttta
    26701 atgataaatt aaaagaagag tttctccagg aatggccttt ggataggatt ttaacaatgt
    26761 caatcgatga atatgtaata ggaaagggac agcaaaataa atctttatgc tacgctcttg
    26821 agaagggaaa atacaaaaat ctatttcttg gaatttctgg tggctcagct tcaaaatttg
    26881 gtatttattg gaataaaaaa acaaacaaat ataaagatca agctaataat gagatttcag
    26941 agttggatca gcgattttca aaattaaaat cagatttgta tgaaattatc aaagaaggta
    27001 ttcgttttaa ctttgaaaat cctatttttg atatgaaaag atcaacaaat gaatttattg
    27061 gtcgttctgc tatggtgaca aaattacttt gtatctatac tgagggagat cctttctttg
    27121 gtgtaaatat taatagtcag aaagaatttt ggaaccactt tgtttctcag acaaatcaag
    27181 gtggacctta tctgcaaaat cataaaataa ttgaactggt gtccaaaact tatcctgagt
    27241 tggagccatc gaaattagga actatgcttt ttgagtattc taagcttttt atggaaaata
    27301 aggaagacaa tagtacaatg gattcatcaa acaattttag tcatcaatta actcaatctc
    27361 tattaaagtc tccaaacctt atccttcgtg gtgctcctgg cacaggaaag acttatcttg
    27421 ctaaagaaat tgccaaagaa ttaacggatg gcaacgaaga ccaaatcgga tttgtacaat
    27481 ttcacccatc atatgattat acggattttg tagaaggttt aagaccagta tcaaatgggg
    27541 atggagctat tgagtttagg ctacaggacg gtatttttaa agatttttgt cagaaagcaa
    27601 aagaaaccca attgattgga ggacaagata attttgatga ggcttgggat tcttacttag
    27661 aatatataaa tgttgctgaa gaaaaagaat atataacaaa aacatcttac ttatctgtta
    27721 atagtagaca aaatttatca gtaaattatg atagtggtgt tccaggatgg tcactaccta
    27781 gcaaatatgt ttacgagttg tataaagata aaaattataa taagcaagaa tactacaaaa
    27841 gtggtggaaa aactgtccta gaaacattga gaaagagatt tggtttgaaa gactatgttt
    27901 ccccaacaga aattgatact gataagaaat tcgttttcat catcgatgaa atcaatcgtg
    27961 gggagatttc taagattttt ggcgaactct ttttctctat cgaccctggc tatcgtggtg
    28021 aaaaaggaag tgtttctacc caatatgcaa atctacacga aactgatgaa aagttctata
    28081 tccccgaaaa tgtttacatc atcggaacta tgaatgatat tgatcgttca gtggatacct
    28141 ttgattttgc tatgcgtcgt cgttttcgtt ttgttgaagt tactgccgag ggtcaagttg
    28201 gcatgttgga taaagagctg aatatccatg cagaagaagc aaaaattcgt ctaagaaact
    28261 tgaacgctgc tatcgaaaat gttcaggaat taaacagtca ttatcatatt ggaccaagtt
    28321 attttcttaa gttgaaggat gtagattttg actatgaatt actctggtct gattatatta
    28381 agcctctcct agaagactac ttgcgaggtt cttatgatga ggttgaaact ttggaaactt
    28441 tgaaaaaagc atttgaactg acaaataatg atcaaactgg tcaacaagat actggtgata
    28501 atgatgcgga taactgataa tcagcataaa attgctaaag aagactttgt cgcagaatat
    28561 cccaaactaa gtcaagctct tcttgataga acactggata acctttctag agaggataat
    28621 atctttattt ttccaaatga tttgactcat actcctgatt tggataagga ccaaaagatt
    28681 tttgaaacag tcaatcagaa aatcaagaca gggaacgtga ttggttttct tggatatggt
    28741 caggaaagat taacgatttc ctcacgattt tctgatgaga gtaatgacca ttttttgcat
    28801 tatctcttaa acaaggttct tcatatcaat ctcactagtt tagatgttgc tttgtctcgt
    28861 gaagagaggc tttatcaact tttgatgtat ctcttcccca agtatctaca agctgctatt
    28921 cgaaaaggtc tttataagga atatcatcga ttttctcata acgacagtca tgttaaggga
    28981 gtaattgatg taagaaacca tctcaagaaa aatcttcctt tcacgggaaa tattgcctac
    29041 acaacgagag agttcaccta tgataatccc ctcatgcagt tggtccgtca cactattgaa
    29101 tgcattaaga atcagaaaag cattggtcaa ggggtactag ataatctctc aactagtcgt
    29161 gaaaacgtat ctgaaatcgt gcgtgtaacg ccctcttata aactagctga tcgtgctaag
    29221 attatcagaa tgaataaaat caaacttatc cgacacgcct atttcagaga gtatagaaaa
    29281 ttacaggaac tctgcttggt gattctgagt agagaaaagc atggtcttgg acctcaagcc
    29341 caaagggtac atggtattct ctttgatgtt gcctggcttt gggaagagta tgtttacacc
    29401 ttgttgccaa aaggttttgt acatcccaga aataaggata agacggatgg aatttcagta
    29461 ttttctgttg ggaaacgaaa agtatatcca gatttttatg atagagaacg aaagattgtt
    29521 ctagatgcaa aatataaaaa actggaattg actgaaaaag gaatcaaccg tgaggactta
    29581 ttccagctga tttcctattc ttatatttta aaagctgaga aggctggact tgtttttccg
    29641 agcaaggaca aggttattga taatgagata ggaaacctag caggttatgg tctattcgaa
    29701 tccctcagaa tgcctcattc tatagtacat tttgtaaaat gatggaaaat tcagaagaaa
    29761 attttaaagc gattattgat gaagaagtgg ggagaaaata atttcccctc tttcttttat
    29821 ttttaacaca agtaaaaccc gaacgatata ttttaattca taaaataatt tgacaaaaac
    29881 tgtactttgg tttataatga attaaggaaa cgtcggaaaa ggcgtagtga tgcaagagca
    29941 taggtaggtc attacaaaag aaacgagaca tcgatatgtt aaatgaattt ccaatttttg
    30001 attacgaaga tattcaattg attccaaata aatgtgtcat taaaagccgt gcagaagcgg
    30061 atacaagtgt cactttagga aatcacacct ttaaactacc tgttgtgcca gcgaatatgc
    30121 agacgatttt ggatgaaaat gtagcagagc aactggctaa aggtggttac ttctacatta
    30181 tgcaccgttt tgatgaggca ggacgcattc cttttattaa acgaatgcac aatcaagggc
    30241 tcattgcttc catatctgtc ggtgttaagg actatgagta tgatttcgtt agacagctca
    30301 agactgatgc tcctgagtat atcactattg atattgctca tggtcatgcg gatagcgtga
    30361 tttctatgat tcaacacatc aagaaagaat tgccagatac ctttgtcatt gctggaaatg
    30421 tgggaacacc agaagctgtg cgtgaattgg aaaatgctgg tgcagatgct actaaggtcg
    30481 gaatcggtcc tggtaaggtt tgtatcacca aggttaagac tggttttggt acaggtggtt
    30541 ggcagttggc tgctctacgc tggtgtgcca aggctgcgcg taaaccgatt atcgctgatg
    30601 gaggaattcg tactcacggt gatattgcca agtctatccg cttcggtgct agcatgatca
    30661 tgattggttc cctctttgca ggacatattg aaagtccagg gaaaacgatt gaagtcgatg
    30721 gtgaacagtt caaagaatat tatggttcag cctcacaata tcaaaaaggt gcttacaaaa
    30781 atgtggaagg caaacgtatc ttgcttcctg ctaaaggtca tctgcaagac actttaactg
    30841 agatggaaca agaccttcaa agtgctattt cttatgcagg tggacgtcag gttgctgacc
    30901 ttaaacacgt tgattatgtg atcgtgaaaa actccatctg gaatggggat gcttcccact
    30961 aagacggggt ctttgaccaa aaaacttgtt attagagcaa atttctgtta taataaaaca
    31021 agtttccacc cttagtgtaa tggatatcac gtaagattcc ggttcttgag atgggggttc
    31081 gattccctca gggtggatgt aaacatccta aaaagccttt aatagggctt ttttctttat
    31141 cctgacccaa atttgccgct aaaactgaga atctctgtct aaagaattcc caaatgcttt
    31201 ccagtcccgt tttagagtga ctcagggggc tttttttgat ataataaaaa ggactgttat
    31261 cagttagaaa gaggttggta tgaaagaatt acaaactgta ctaaagaacc attttgcaat
    31321 cgaatttgca gacaaaaatt tactggaaac tgcctttact catacgagtt atgccaatga
    31381 gcaccgcctc ttaaaaattt cacacaatga acgcttggaa tttttaggag acgctgttct
    31441 acagttattg atttcagaat atctatataa aaaatatcct aaaaagcctg aaggtgacct
    31501 atcaaaactc cgtgctatga ttgtccgtga ggagagtttg gctggctttg cgcgtgattg
    31561 ccagtttgac cagtttatca agctgggtaa gggggaagaa aaatctggtg ggcgcaatcg
    31621 tgataccatt cttggtgatg cctttgaagc ctttcttggt gcccttcttt tggacaagga
    31681 tgtggccaag gtcaaggaat ttatctatca agtcatgatt cctaaggttg aagcaggcga
    31741 atttgagatg attacagact ataaaaccca tctccaagag ttgcttcagg tcaatggtga
    31801 tgtggctatt cgttatcagg tgatttctga aacgggtcct gctcacgata aggtctttga
    31861 tgtagaagtt cttgttgaag gtaagagcat cggtcaaggt caaggtcgtt ctaagaaatt
    31921 agcagagcag gaagctgcca aaaatgccgt tgagaaaggg ctggattcat gtatttaaag
    31981 gaaatcgaaa ttcagggatt caagtctttt gctgataaga ccaaggtcgt ctttgaccaa
    32041 ggtgtgacgg cagtcgttgg acccaatgga tctggaaagt cgaatattac agaaagtctg
    32101 cgatgggcct tgggagagtc tagtgtcaag agtctccgtg ggggcaagat gccggatgtc
    32161 atctttgctg gaacagaaag tcgtaaaccg cttaattatg cttctgtagt tgtgactctg
    32221 gataatcatg atggatttat caaggatgca ggtcaagaaa tcagagtaga acgccatatc
    32281 tatcgtagtg gggatagtga atacaaaatt gacggcaaga aagttcgtct tcgtgatatt
    32341 catgatctct tcttggacac aggtttggga cgagattcct tttccatcat ttcccaaggc
    32401 aaggttgagg agatttttaa ttctaagcct gaggaacgcc gagctatttt tgaagaagct
    32461 gcaggagttt taaaatacaa gactcgtaga aaagaaactg agagcaaatt gcaacaaact
    32521 caggataatc tggaccgctt agaggacatt atctacgagt tggataatca aatcaagcct
    32581 cttgagaagc aagctgagaa tgcccgtaag tttttagact tggaaggaca acgtaaggct
    32641 atttatttag acgtgctggt tgctcaaatc aaggataata aggctgaact agactcgaca
    32701 gaagaagagt tggctcaggt tcaggaactc ttgactagtt attaccaaaa gcgtgaaaaa
    32761 ttagaagagg aaaatcaaac tcttaaaaag caacgccaag atttgcaggc tgaaatggcc
    32821 aaagaccaag gcagtttgat ggatttgacc agtctgatta gtgacttaga gagaaaatta
    32881 gccctatcga aactggaatc tgagcaagta gccctcaatc aacaggaagc acaagcccgt
    32941 ttggctactt tggaggataa gagaagttca ctcagccaag aaaaatctga taaagaaagc
    33001 tctttagctc tgttagaggg aaatctagtc caaaataatc aaaaactcaa tcgtttagaa
    33061 gctgaattgc tggctttctc agacgatcct gatcagatga ttgagctctt acgtgaacgc
    33121 tttgtagctc ttttacaaga agaagcggat gtctcaaacc agttgacccg tattgagaat
    33181 gagttggaaa atagtcgtca gctttctcaa aaacaagcag atcaactaga aaagctgaaa
    33241 gagcaattgg ctatagctaa agagaaggct agtcagcaaa aggaagagct tgaaactgcc
    33301 aaggagcagg ttcagaaatt attggctgac taccaagcta ttgccaagga gcaagaggag
    33361 cagaaaactt cctatcaagc tcaacaaagc caactctttg accgtctgga taatctcaaa
    33421 aacaagcagg ccagagctca aagtttggaa aatatcctga gaaatcatag taacttttat
    33481 gcaggtgtta agagtgttct ccaagaaaaa gatcgcctag gtgggattat tggtgcagtc
    33541 agtgagcatc tgacctttga tatgcattat caaactgccc tagaaattgc acttggagcg
    33601 agtagtcagc acattattgt agaagatgag aatgcggcaa ccaaagccat tgatttcctc
    33661 aaacgaaaca gagccggtcg tgcaaccttt cttcctttga ccactattaa ggcgcgtacg
    33721 atttctagtc agaaccaaga tgctatcgct gtaagcccag gtttccttgg gatggcagat
    33781 gagttagtta ctttcgatac tagactggaa gccattttca agaacttgct agctacgacg
    33841 gctatctttg ataccgtaga acatgcgcgt gaagctgctc gacaagttcg ttatcaggtt
    33901 cgcatggtga cattggatgg gacagagctt cgtacaggtg gttcctatgc aggtggagcc
    33961 aatcgtcaga acaacagcat cttcatcaag ccagaactgg agcaattaca aaaagaaatt
    34021 gctgaagaag aagcaagctt ggattcagaa gaagtggctt tgaagacctt gcaagatgag
    34081 atggccagat tgaccgagtc attagaagct attaaatctc aaggagagca ggcacgtatt
    34141 caggagcaag gcttgttcct cgcttatcag caaactagtc agcaagttga agagctagaa
    34201 actctttgga aactccaaga agaggaaata gatcgtcttt ccgagggaga ttggcaagcg
    34261 gataaggaaa actgccaaga gcgtcttgct gcaatcgcca gtgacaagca aaatctggaa
    34321 gctgagattg aagagattaa gtctaacaaa aatgccatcc aagaacgcta tcaaaacttg
    34381 caggaagagc tagcgcaagc tcgtttgctt aagacagaac tgcaagggca aaaacgttat
    34441 gaagttgctg atattgagcg tttaggcaag gaattggata atcttaatat cgaacaagaa
    34501 gaaatccagc gcatgctcca agaaaaagtt gacaatcttg agaaagttga tacggatttg
    34561 ctcaatcagc aggccgaaga agccaaaact cagaaaacaa atctccaaca aggtttgatt
    34621 cgcaagcagt ttgagttgga tgatattgaa gggcagctgg atgatattgc tagtcatttg
    34681 gatcaggctc gccagcagaa tgaggagtgg attcgcaagc aaacacgtgc tgaagctaag
    34741 aaagaaaagg tcagcgaacg cttgcgccat ctacaaagtc aattaacaga ccagtaccag
    34801 attagctata ctgaagctct agaaaaagcg catgaattgg aaaacctcaa tctggcagag
    34861 caagaagtta aggatttaga gaaggctatt cgctcactgg gtcctgtcaa tatagaagct
    34921 attgaccagt acgaagaagt ttacaaccgt ctggactttc taaatagtca gcgagatgat
    34981 attttgtcag cgaaaaatct gctccttgaa accattacag agatgaatga tgaggttaag
    35041 gaacgcttta aatcaacctt tgaagctatt cgtgagtcct ttaaagtgac ctttaagcag
    35101 atgtttggcg gaggtcaggc agacttgata ttgactgagg gcgacctttt aacagctggt
    35161 gtggagattt ctgttcaacc tccaggtaag aaaatccagt cgcttaacct catgagtggt
    35221 ggtgaaaaag ctctatcggc tcttgccttg ctcttctcca ttattcgtgt caagactatt
    35281 ccatttgtta tcttggatga ggtggaagct gcgctggatg aagctaatgt taaacgtttt
    35341 ggggattacc tcaaccgctt tgacaaggac agccagttca tcgtcgtaac ccaccgtaag
    35401 ggaaccatgg cagcggctga ttctatctat ggagtgacca tgcaagaatc aggtgtctca
    35461 aaaattgttt cagttaagtt aaaagattta gaaagtattg aaggatgaca attaaactag
    35521 tagcaacgga tatggacgga accttcctag atgggaatgg acgctttgat atggatcgtc
    35581 tcaagtctct cttggcttcc tacaaggaaa aagggattta ctttgcggtg gcttcgggtc
    35641 ggggatttct gtctctggaa aaattatttg ctgatgttcg tgatgacatt attttcatcg
    35701 cggaaaatgg cagtttggta gagtatcaag gtcaggactt gtatgaagcg actatgtctc
    35761 gtgactttta tctggtaact tttgaaaagc tgaaaacgtc accttatgta gatatcaata
    35821 aactgctctt gacgggtaat aagggttcat atgttctaga tacggttgat gagacctatt
    35881 tgaaagtgag tcagcattat aatgaaaata tccaaaaagt agcgagtttg gaagatatca
    35941 cagatgacat tttcaaattt acaaccaact tcacagaaga aacgctggaa gatggggagg
    36001 cttgggtaaa cgaaaacgtt cctggtgtta aggctatgac aactggcttt gaatctattg
    36061 atattgttct ggactatgtc gataagggag tggccattgt tgaattagtt aaaaaacttg
    36121 gtatcacaat ggatcaggtc atggcttttg gagacaatct taatgactta catatgatgc
    36181 aggttgtggg acatcctgta gctcctgaaa atgcacgacc tgaaatttta gaattagcaa
    36241 agactgtgat tggtcaccat aaggaccagt cggttatagc ttatatggag ggcttataat
    36301 ggcagatata aaattaatcg cattggactt ggacgggacc ttgctgacta ctgataaaag
    36361 gctgacggat cgtaccaagg aaaccttgaa agctgcgcgt gatcgtggta tcaaggtcgt
    36421 attgacaact ggtcgtccct taaaagctat ggatttcttt ctccatgagc tagggactga
    36481 cggtcaggaa gatgagtata ccattacttt taatggtggt ttggttcaga aaaatacagg
    36541 tgaaatcctt gataagacag tcttttcata tgatgatgtg gcacgcttgt atgaagaaac
    36601 agagaaatta tcactgcctc ttgacgctat ctcagaagga actgtttatc aaatccaatc
    36661 ggaccaagaa agtctttatg ccaaattcaa tccagctttg acttttgttc cagttgactt
    36721 tgaagacctg tctagtcaaa tgacctacaa caaatgcgtg actgcctttg ctcaagaacc
    36781 cttggatgca gccattcaga agatttctcc agaattgttt gaccaatatg aaatctttaa
    36841 atcacgtgaa atgttgctag agtggtcacc aaagaatgtt cataaagcaa caggtttggc
    36901 aaaactaatc agccatctcg gaatcaacca aagccaagtt atggcctgtg gtgacgaggc
    36961 caatgacctt tctatgattg aatgggcagg tcttggtgtt gctatgcaaa acgctgttcc
    37021 tgaagtaaag gcagccgcaa atgtagtaat gccgatgacc aacgatgagg aagctgtcgc
    37081 ctgggctatc gaagaatatg tgctaaagga gaactaagat atgggattgt ttgaccgtct
    37141 attcggaaaa aaagaagaac ctaaaatcga agaagttgta aaagaagctc tggaaaatct
    37201 tgatttgtct gaagatgttg atcctacctt cacagaagtt gaggaagttc ctcaggaaga
    37261 agcagaggtt gaaattgttg aacaagctgt gttccaagag gaggaaatcc aagacacagt
    37321 tgaagaaagt caggattcag agccagctgt aggggtttct caagaagaaa tagaagaatt
    37381 accaaactca gaagaattac cagaggaaga gaagcttgag cacgaaggaa ctgtagaaga
    37441 aaataattct gaagttcttg aaccagaaag gcctcaaaca gaagaaactg ttcaggaaaa
    37501 atatgaccgc agtctcaaga agactcgtac gggcttcggt gctcgcttga acgccttctt
    37561 tgctaacttc cgctctgttg acgaagaatt tttcgaggaa ctggaagaac tgctgattat
    37621 gagtgatgtt ggtgtccaag tcgcttctaa cttaacggag gaactacgtt acgaagccaa
    37681 gcttgaaaat gccaagaaac ctgatgcact tcgtcgtgtc atcattgaga aattggttga
    37741 gctttatgaa aaggatggta gctacgatga aagcatccac ttccaagata acttgacagt
    37801 tatgctcttt gttggtgtga atggtgttgg gaaaacaact tctattggaa aactagccca
    37861 ccgctacaaa cgaactggta agaaggtcat gctggttgca gcagatacct tccgtgcggg
    37921 tgcagtagct cagctagctg aatggggccg acgagtagat gttccagtag taactggacc
    37981 tgaaaaagct gatccagcca gcgtgatctt tgacggtatg gaacgtgccg tggctgaagg
    38041 tatcgatatt ctcatgattg atactgctgg tcgtctgcaa aataaggata accttatggc
    38101 tgagttggaa aagattggtc gtattatcaa acgtgttgtg ccagaagcac cacatgaaac
    38161 cttcttggca cttgatgcat caacaggtca aaatgcccta gtacaggcca aagaattttc
    38221 gaaaatcaca cctttaacgg gaattgtttt gactaagatt gatggaactg ctcgaggagg
    38281 tgtggttcta gccattcgtg aagaactcaa tattcctgta aaattgattg gttttggtga
    38341 aaaaatcgat gatattggag agtttaactc agaaaacttt atgaaaggtc tcttggaagg
    38401 cttaatctaa tcagaagcaa aaatcctgca aggtacaaac ttgcaggaaa tttttttatt
    38461 cgaaacgacc atcttgacga taggcgatat ctggttgcca agtccatttg gcaccgaatt
    38521 tttcaagtag gtcaaagctg gcttgaggtc ccatgcttcc agctttatag tcatgaagtg
    38581 gggcaccatt ttcagcccag agctcttcaa tacggtcaat caacttccat gatgcaccaa
    38641 cttcatccca gtggctaaag ttagttgagt tgttatttag gacatcataa atcaatttct
    38701 cgtatggttc tggagaagca ccagttgcag tcgcatctgt acggtaatca agtgagttag
    38761 gagccaagtt aaattcttct cctacttgct tcccatttag gctaagagag aagccttctg
    38821 ttggttgaat atagatggtc aaaatatttg gagcaagtgg ttctccaaag atagaatcca
    38881 tttgtttaaa aacgatgttg acatgagttc ctttttcagt cagtcgttta cctgtacgga
    38941 aaaagaaagg aacactacgg aatcgatcgc tgtctacaaa gaaggcacca gatgtaaagg
    39001 tttcagttgt tgattctgga ttcacatttg gctcgctacg ataagagatg tatttcatgc
    39061 catcaatctt accagagcgg tattgcccac ggataaagtg ttctttgagt tcttcatcag
    39121 ttggatgata gaggttttta aagaccttaa tcttttcagc acgaatctcg tcttttgtga
    39181 agattgctgg tttgtccatg gcgaggagcg aaagaagttg tagagtgtgg ttttggacca
    39241 tgtcacggag ggcaccggat tggtcatagt agccaccacg ttcttctaca cccaagcgct
    39301 ccgcaaaggt aatttgaaca ttgtcgataa aatccttgtt ccaaacgttt tcaaaaatca
    39361 agtttgcaaa gcgaactgca aatatgcttt ggatcatttc cttaccaaga taatggtcga
    39421 tacggaaaat ttgttcttcg tcaaatgttg ctaggagttc gtcattcaac ttgcttgcag
    39481 ttgcgtaatc tgtaccaaat ggtttttcaa cgatcaagcg ctcaaaacct ttgccatcga
    39541 caatgttttc agatttgagg tgtttggcaa tggttccaaa gaactgaggt gccatagaca
    39601 agaagaagag cttattatgt tcagcttggt atttttcatt aagctcagct tgtaattgac
    39661 gcaaagcaat ataatgttcc gaatcattga catcatggct ttgatagtag aagtggctag
    39721 caaattcttg ggcttgctcg gtactatctg ccaaatcaag gatggactcg acaactacag
    39781 attcaaaata ttccttactc caaggtctac gggcagttcc aataacggca aagtgcttgg
    39841 aaagattgcc ggatttatat agtctaaaaa gggaagggta gagcttgcgt ttagccaggt
    39901 ctccactcgc accgaaaatt gtaacaataa ccttagatga catctagcta cctaatttct
    39961 atttttattc ctagtcttgc taggtatgag gaaacctcat ttcataaact taattctaac
    40021 ataattttcc gaaaaatcaa aaattccaat acgaggtaga aaaactgcaa ggaaatcctt
    40081 acagtttgag tttagacgtt taagacctta tctaagaact ctttcagacg agggtgttgt
    40141 gggttatcaa agatttggtc aggtgttccg tcttcaagga actcgccatc tgcagtaaag
    40201 ataacgcggt tggcaacctg acgagcaaat cccatctcat gggttacgat aatcatggtc
    40261 ataccttgct cagccaattc cttcataacg ttaagtacgt ctccaaccat ctcagggtca
    40321 agggcagaag ttggttcatc gaagagcatg atgtctggat tcattgctag gccacgagcg
    40381 atggccacac gttgtttttg accacctgat aggctatctg gattggcatt agctttatct
    40441 gctagtccaa ccttttcaag caactccatt cccaattcct cagcttcttc cttagtcatc
    40501 aacttgtgct caataggagc aaaggtgatg ttgtccaata cagacatatg agggaagagg
    40561 ttgaagtgtt ggaataccat gccgatattt tcacggacgt ggtcaacatt ggttgttttt
    40621 tcagttaaat catagccgtt cacagtgatg tgaccgctag tgacttcttc taaaagattg
    40681 aggctacgga ggaaagttga cttaccagaa cctgaaggac cgatgataca aacaacatct
    40741 ccttcataga acttagtcgt aattcctttt aggacttcat tttttccata gtgcttgtgt
    40801 aaatcattta catcaatttt taattttgcc attaacgaat cctcttttct aagcgtttcg
    40861 ctagtctagt caaaagtgtg ataattacaa gatagaagat agcaaggatt gcatacatct
    40921 tgaaactttg gtagttacga gcaatgataa tcttaccagt ttggaagagt tcaaccaaac
    40981 cgatagcaga tacgatagtt gtatctttaa gagcgataac gaattggttg acaaagtttg
    41041 gcaacatcaa tttagttgct tgtggcaaga taatcttacg catggttttt ccataagaga
    41101 tacccaagct tcggctggct tccatttggc caactggaac ggcctgaata ccaccacgaa
    41161 cgatttcagc gatataagca gccgcattga gtgagagggc aattgttcca gctacaaagt
    41221 cgttaattgg gctttgttgg cctgtgatag actcgatgaa gtttggaatt ccccagaaga
    41281 tgaaggctgc aagaatcatc aatggaatac cacgaataac gtcaacgaaa atctcagaga
    41341 tgacgcgaag agatttgtat gggctaacgc taaacatacc gaagataatt ccgatgacaa
    41401 tggcaatagc aaatgagata agagctagag caagagtgat accaagaccg ctaaggagtt
    41461 gtttgtagtt gttttgaagc aagccccaga gcgttgtttc gtcaacagta cttgttgaag
    41521 cagttgaaga ttcgctagct aggtatttgt caagaatctt ttggaattca ccgtttgctt
    41581 taaggtttgc aagtccgttg ttgaacattt caatcagttc tggatttgct ccttttttaa
    41641 cggcaaaggc tgtttcaccg attggagttc cagagattgg agttttcaat ttttgacctt
    41701 ggctgataga atatttgaga acaggttcat catccataac ggcatcaatg gcaccagtgt
    41761 ttaaactgtc atacattgaa gaaccatcag caaaggtttt gattttgtaa ccgtatttgc
    41821 tttgattttc tgttaggaag gtttgagaag cagttccgtt tttaacaccg actgtctttc
    41881 cttttagatc ttcataagaa gcaatattgc ttgattcttt gacaccaaga atggtattag
    41941 cagtgtagta tgattctgag aagtcaaaag ttgccttacg agcatctgtg acagacatac
    42001 cagcaatgat accatcggct tgaccagctt ggacagcact gatagcagca tcaaaaccag
    42061 ggttggtgat ttcaatttca aaaccttggt ctttagcgat tgccttaatc aattccatat
    42121 caataccagt gtattggttg cttgaatttt ggaaaacaaa aggtgcaaaa gaagaatcgc
    42181 tggcaatgat atatttagcc ttaacaggaa tagcttttaa tcctgcgaga gtagttgtag
    42241 ttggcactgc tgaagatgat gaagcagtcc atttcttgat aattttatca agactaccat
    42301 cttttttcat ttcagccaag gcttggttaa attcagtaac caggtgctcg tatttacttc
    42361 cttttttcac accgaaagca aaacttccta cagcttcacc atccatttca atatggaggt
    42421 cttgaccttg gttaatggca tattcgataa caggtttgtc atccatcatg gcatcgatgg
    42481 caccagcact caagctgttg ttcattaaat ccccagtgtc aaatgtttta atagtaaagc
    42541 cgtatttatc tttgattgtt tcaaggaaac gttgagcggc agttccgttt ttaacaccaa
    42601 cggttttgcc agttaattgg tcgtacttgc taattttgtg tgactttgta gtagcaatga
    42661 caacttttgt atcatagtaa gtatcagaca tggtgaagac tttttcacgt tctttagtct
    42721 ttgtcatccc tgccatgata gcgtcggctt gcccagcttg aaccgcattg actgctgcgt
    42781 caaatccagg ataggacatc tgaatgttcc agcctttaat ctcagcgact ttgttaataa
    42841 tgtcaacatc aattccttta taagtttgat ctgaatcttt aaactcaaaa ggtgcatagg
    42901 cggtatcaga aacaatctta atcgtttctg ctttggcaat acctaatgag aaaattggga
    42961 ataaaattag caaaaatgct agaaattttt tcttcatttt tagtctcctt ttccgaatat
    43021 tctctcatta tatcagaaaa agtaaaaaaa ggcaaatttt tatatttttc gtgtcagaaa
    43081 atataacatt ggtttttcct tttctttctt gaattgctat taaaaagtgc tataataata
    43141 gtatatatag aagaaaagag gacggggata tgaagaacaa aagaatattt aaagacttcc
    43201 aagcttcaaa aatgagttta aacatttaca caagcctctt gttagccttt gtttttgtct
    43261 tcataggaga gtttgtggct tatactttat atggtattag tttgttagct ctcatcggac
    43321 ttgctagaaa ttttggagag gctggtcaaa atcttgcaag ctacttgcag accttgcatc
    43381 agagcttgac ggataaaaca agtgactttc gtttaatttt aggattactg gcctttggtt
    43441 ttattcttaa cactgtgttc agatggacaa gaaaagttga gaaaagacct attcgaacct
    43501 tgggatttta tagagagaat ttcctcagca atcttctgaa aggatttagt ctaggcctgg
    43561 cactttttct tctgaccttg ttaggtttgg tggtcttagg tcaatatcgt ttggaatcca
    43621 ttcacttgaa tccttattct cttgcctttg tcgtctttac tatcccattt tggattttac
    43681 aggggacagc agaagaagtg gtggcccgtg cttggctact tcctcaattg gcctcaagaa
    43741 ccaatctaaa actagctatt cttatatcta gcctgttctt taccctgctt catatgggca
    43801 attctggcct cacccctcta tctctagtaa atctcttttt attcggagtt gccatggctc
    43861 tttaccttct caaaactgat acagtttggg gtgttgcagg tattcatggt gcttggaatt
    43921 ttgctcaggg taatctcttt gggattttag ttagtggtca accgtcagga acgtctctga
    43981 tgaccttttt accacaaggc aatcaagatt ggctatcagg tggttctttt ggcatagaag
    44041 gttccattat gacaagtctg gtattactac tgctgattgt ctatcttgct aataaattaa
    44101 agaaagaaaa tgaaaggatg tgacttcggt ccgtcctttt cttcgtgaaa atactataag
    44161 tatgctaaaa taggaatagc acatggagag aggattctta tgatcaatca cattacagat
    44221 aatcaattta aactagtatc aaaatatcaa ccatcaggag atcaacccca agctatcgag
    44281 cagttggtgg ataacattga ggggggagaa aaagctcaga ttctgatggg ggcgactgga
    44341 acagggaaga cctatactat gagtcaggtc atttctaaag tcaataaacc aactctggtt
    44401 attgcccaca ataaaactct ggctggtcag ctctatgggg agtttaagga atttttccct
    44461 gaaaatgcag ttgagtattt cgtatcctac tatgattatt accagccaga ggcctatgtc
    44521 ccttctagcg atacctatat tgagaaggat agttctgtca atgacgagat tgacaagctt
    44581 cgccactcag ctacctcagc ccttttggag cgtaatgatg ttattgtcgt ggcctcagtc
    44641 tcttgtatct atggtttggg ttcgcccaag gaatacgctg atagtgtcgt tagtctccgt
    44701 cctggtctag agatttctcg tgataaactc ttgaatgact tggtcgatat tcagtttgaa
    44761 cgtaatgata ttgatttcca acgcggaaga tttcgcgttc gtggggatgt ggtagagatt
    44821 ttcccagctt cccgagatga acatgccttt cgagtagaat tttttggaga cgaaattgac
    44881 cgtattcgtg aagttgaggc tctgacaggt caggtgttgg gagaagtgga tcatttagcg
    44941 attttcccag cgacacactt tgtgaccaat gacgaccaca tggaagttgc cattgcaaag
    45001 attcaggccg agttggaaga acaattagct gtctttgaaa aggaaggtaa actgcttgaa
    45061 gcccagcgtt tgaaacagcg gacagagtat gatatcgaaa tgttgcgtga gatgggctat
    45121 accaatgggg ttgaaaatta ttctcgccac atggatggac ggagcgaagg agagcctcct
    45181 tatacgcttc tcgacttctt cccagatgat ttcttgatta tgattgacga gagtcatatg
    45241 accatagggc aaatcaaggg catgtacaat ggagaccgtt cgcgtaaaga aatgctggtt
    45301 aattatggtt tccgtttgcc gtctgctttg gacaatcgtc ctctccgtcg ggaggagttt
    45361 gagagtcacg ttcatcagat tgtttacgtt tcagcgacac ctggtgacta tgaaaatgaa
    45421 cagaccgaga cagtgattga gcaaatcatt cgtccaacgg gactcttgga tccagaggtg
    45481 gaagtccgtc cgactatggg acagattgat gacctcttgg gtgaaatcaa tgcccgcgtt
    45541 gaaaaaaatg agcgtacctt tatcacaact ttgaccaaga aaatggcaga ggatttgacc
    45601 gactacttca aggaaatggg tatcaaggtc aagtacatgc actcggatat caagaccttg
    45661 gaacggacgg agattatccg tgacctgcgc ttgggtgtct ttgatgtctt ggtcggaatt
    45721 aacctgctcc gtgaaggaat tgacgttcct gaagtgagcc tcgtagctat tctcgatgct
    45781 gacaaggaag gtttccttcg caacgaacgt ggactcatcc agactattgg acgtgctgct
    45841 cgtaacagtg aaggccatgt catcatgtat gcagacacgg ttacccagtc tatgcaacgt
    45901 gctatcgatg aaactgcccg ccgtcggaaa attcagatgg cctataatga agagcatggt
    45961 atcgtaccac agacaatcaa gaaagaaatc cgtgacctga ttgccgtgac caaggcagtt
    46021 gctaaggaag aggacaagga agtcgacatc aatagcctca acaaacaaga gcgcaaagaa
    46081 ctcgtcaaga aactagaaaa acaaatgcaa gaagccgtcg aagtgcttga ctttgaactg
    46141 gcggctcaga tccgtgatat gatgttggaa gtcaaggcct tggattaggg gaatagtatg
    46201 atttatttaa gaaagttaaa gagagaagat ttgatgtctt tatgggaaat ggcttattca
    46261 caacttaatc cagtttggaa acagtatgat gctccctatt atgatgatta tcagtatttt
    46321 tcaaatttta aagaattcga actacaaaaa tcagaatcca ttttaagcaa ctcaaatcgc
    46381 cttggtattt ttgttgatga taaactagtt gggactgttt cgcgttattg ggtatgtaaa
    46441 caaacaagat ggatggaatt gggaattggt atttatgata aaaaattctg gaacactggt
    46501 attgggaaag ttgctatgtt gcagtggata gataggacgt ttcaggatta cttggagttg
    46561 gagcatctgg gtttgacaac ttggtcaggg aatattggta tgatgaaact tgctgaaaaa
    46621 ttaagaatga aaaaagaagc tcatattcca aaagttcgtt attatcaagg taaatatttt
    46681 gatagtatta aatatggtat tttgagagaa gactgggaga aaataaatga cggttattat
    46741 caaatcaatg gaaactccta aagagataga aggtaaatcc cttgttcact ggcaaacgtg
    46801 gagagagtct tatgatgacc ttttgcctgc ggaatttcag gatacaatga cattagaaag
    46861 atgtcgattc tttagtcaaa agtatccaga aaatacattg attgcgatgg atggcgtgaa
    46921 ggtggttggt tttatcagtt atggcaattt tcgtgatgag actattcaag ctggtgaaat
    46981 tattgcttta tatgttttaa aagactatta tggaaaaggt atcgcacaaa agttaatgaa
    47041 agcagctttg actgctctta atcatttttc tgaaattttc ttatgggtat tgaaagataa
    47101 caagcgcgcc attgctttct atcaaaaaat gggttttact tttgatggac aagaaaaaat
    47161 acttgaactt ggaaagccta taaaggaaaa acgaatggtg ttctattcta aataatttta
    47221 aaaaagtaaa agataatatc tctggtagta agtctgaaaa tttaataaat tagaaagcga
    47281 gtaaatttat gtcccgttcc caattaacga ttttaaccaa tatttgtctg attgaagacc
    47341 tcgaaactca gcgcgtggtg atgcagtatc gcgcccctga aaacaatcgc tggtctggtt
    47401 atgcctttcc tggaggtcat gtagaaaatg atgaggcttt tgcggagtct gtcattcgtg
    47461 aaatctacga agaaacaggg ttgactatcc aaaatcctca acttgtcggc attaaaaatt
    47521 ggccactaga tacaggtggg cgctatattg tcatttgtta taaggcgact gagttctctg
    47581 gtacccttca atcttcagaa gagggagaag tttcttgggt gcaaaaagac cagattccaa
    47641 acttaaatct ggcctatgat atgctaccat tgatggaaat gatggaagct cccgacaagt
    47701 cagagttttt ctatcctcgc cgtacagaag acgattggga aaagaaaatc ttctagtctt
    47761 ttactaaata acctagctga tccaaggcct cctcgatata gtggaggtct tgttgtgttt
    47821 cggcttcgac taggtggtaa tggatgccat ctgtcaattc agatagaggt ctaaagtcag
    47881 aatgctcgac ttgttctaga aaatgttgca catctctgcg acaagacagt ttaagcaagg
    47941 tttcaatttc tccataaacg ggatggtcaa tcaaggtatt ctggacatgc ccaccattat
    48001 cgacaatagc aaggagttcc tgaccgattt cttcaacttc atgtttcact ttgaaaagtt
    48061 tgtgaacata aggattggta tcaatttgct tatagatgta gccacgattg gtggatagga
    48121 taggagcgcc atcggctctc aaaattgcaa tgtcctgcac aatgacctga cgtgtgacat
    48181 gaaaatgttc cgccaaactt tggccattaa gggctttagg agcttctttc aagagttgga
    48241 gcagggcttg tttgcgatct tttgtcatag cttttccttt taacggcgtt ttcgaagcac
    48301 tttatagaca gctagtgcta atgtatagtc taccatacta tggataattg tgccaaatcc
    48361 aactagtaca aatagaacat agaacatatt ttctacattg gtacccgaag ttgcgtaaaa
    48421 aaggacacag gctaatactt cagcaagggc atgaacaaca gccaaaacaa aattgaaaac
    48481 ccaggaagat tttggtttat ctagggtatc ggggaatttt tgtaggtaaa gagctcctaa
    48541 agcaccaaaa gatatatggg aaaaagcccg aaaaacgata accatgggat agccagccat
    48601 caaaaatcca aaactagagg ctaggatgac aaaaactgcc atcaagggcg acaagaacat
    48661 ggctataaaa atagcgatgt ggctccccaa agtataggaa gcaggtggaa tgacaatctt
    48721 gaaaggcata acaattggaa tcaaaatcgc aatagccgtt aaaagggctg tcattgtcat
    48781 aaattgtgtc tttttccgtg tattcacaag aatctccttt ttaactgcat atacactagt
    48841 atggtacaat aaaccagaca ataaagcaag aatttacttg ggtttataga tcatttttta
    48901 gttaaaagtt atagtagatt gaaactagaa tagtacacct ctacttctaa aacattgtta
    48961 gaaatcgatt tgactgtcct gatcgatttg tcctgttctt atttcgtttt actatagtaa
    49021 agatttcatt aaaaagaaac tgtatagagc aaaatctcca ccttcaggtt tgaaagcgga
    49081 gattgttttt attttttcaa ggtttgtagt cgtggaacaa tggctagggt tagaattgca
    49141 gaaatgacca attcagcaat tgaatttgtt gagataacgg ttgccagaag aagttggata
    49201 tttccattat aaacatttcc aaataggaag aagattcctc caaggacaaa gatagtattt
    49261 gtcaaggaac caagggcccc agctaaaatc agaccagtct tgtttttcat cagtttatag
    49321 actaagtaag gagttaaacc aatcaaaata cgtgggacaa tggcaatgat agctgagtag
    49381 atgtttccgt ttggtacgaa gggagagaag aggtagcttg tcggtagaat cgtaatcgtg
    49441 ttaaccgtca agctaagtaa tcccatcaaa aatccaagtg taaccccaac tcgtggacca
    49501 taaataatgc tggcaataat gacaggaata tgaacaatgg tcggtttgat tggaaatgga
    49561 aaaaggttaa agataagtga gctcagaaag tgtatcacga gcatggtagc aaaaaagata
    49621 gcaatgggtg caatattaga gcgttttttc atcgatagtt tcctttattc tttctaaaat
    49681 aattgtgagg tcagctaaag ctcctcgtcc gtggtctcca caagctagta gggattcctt
    49741 aggagcaatc agctgatagc cgtaggtttc taatgttttc agattattct gagttactgg
    49801 atggtcatac atttttgtat tcatagcagg agctattagt ttgggaatat gacttggtag
    49861 ggctagagct gtactggtta ccatgttgtc cgcaaatccg tgagctagtt ttgcaatagt
    49921 gttagcagtt gcaggtacca cgataaataa atctgctttt tttccaagtt cgatatgatt
    49981 gacctgatca ggatagggtt ccttcatgac atccaagtgg acaggattct gtgagagtac
    50041 ctgtagtgtc aaaggttgga taaactctgt agcagcctga gtcattaaga cagtgacttg
    50101 atggccttgt ttttttagag aactgactaa atctgccgac ttataagagg cgattgaacc
    50161 cgttacagcc aagagaatgt ttgccatagt tttcctttct aagaatgata ggcttgaatt
    50221 ttttcaagga ggagttctgc aatttcttct ttagtctgga ctgtttgaag ctgatttttc
    50281 tcaacaaata tagctcggtg ctgatctgct gaaatttgag tcaggtcatt cgcgatgatt
    50341 aaatctgctt gattcttgat aagacttttt cgtgcaatgt caaccagatg atcttcggta
    50401 acatcaatca gcagtttgaa accaatcaga tgaatagtag gattccattc cttgactagg
    50461 gatatgattt tgggtgtctt tttaaggaac aaaacctgaa cctcatcagt tgaagaaatc
    50521 ttggcctgat gattctgctt gcttaaaaat tcttttagat tggagctagc ctgaacttcc
    50581 tcaagccctg tcatataaac aggagtgtag tcagaaacag ccattgagtg gatcaagacc
    50641 tgataatcct gaacacgttc ttgcatttct attagaaggt ccttggtatt ggtaatttct
    50701 cgaatactta ggttaggatg aggctctggc ttcagagctc gttttgtcgt aattaaacaa
    50761 acttcatgcc ctgcagaaag caaagtctct gtgataattt tccccaagtg acctgtagaa
    50821 tggttagtga tagagcggac gctatcgata gcttcactgg taccgcccga tgtaactaaa
    50881 attttcatag cactattgta cacaaaaata agcggtaagt aaaatgaaag tgataaattt
    50941 ttggtaaaaa cgaagattta ctatagtttc aaactataaa gccatataaa atttaagaaa
    51001 ggattctaaa agccttaaaa acagagatat ttacgaacgt ttagagagtt ttaggatgtt
    51061 aaaaatcttg ttttgtgata taatgaatta tcatataaga ggttagagga attttgaatg
    51121 aaaacagata ttgaaatcgc acagagtatt gagttgaagc caattgttga tgttgtagag
    51181 aaacttggta tttcttacga cgatttggag ttgtacggaa agtacaaggc taaactcagc
    51241 tttgataaaa ttcgtgcagt tgagagcaat ccagtcggta aattgatctt ggttactgcc
    51301 atcaacccaa cacctgcagg tgaaggaaag tcgacgctta ccattggtct tgcggatgcc
    51361 ttgaacaaga ttggcaagaa aaccatgatt gctatccgcg aaccgtctct tggtccagtc
    51421 atggggatca agggtggtgc tgctggtggt gggtatgcac aagttctgcc aatggaagac
    51481 atcaacctcc actttactgg agatatgcat gctattacaa ctgccaacaa tgccctttct
    51541 gccttgattg acaaccactt gcaccaaggg aatgagctgg gaattgatca acgtcgtatc
    51601 ctctggaaac gcgttgtgga cttgaacgac cgtgcgctcc gccatgtgac tgttggtctt
    51661 ggtggtcctc taaacggtat tccacgtgag gacggttttg atattacagt tgcttcagaa
    51721 atcatggcaa ttctttgctt ggcaacggac atcgaggact tgaaacgtcg tttggcgaat
    51781 atcgttattg gttatcgcta tgaccgtacg cctgtttctg taggtgattt gcaggttgag
    51841 ggtgccttgg ctttgatttt gaaggatgct attaagccaa acttggttca gacaatttac
    51901 ggtacacctg cctttgtaca cggtggtcca tttgccaata tcgctcatgg ctgtaactct
    51961 gttttggcga cgacaacagc ccttcacttg gctgattaca ctgttactga agctggtttt
    52021 ggtgcggacc ttggtgctga gaaattcctt gatatcaaga caccaaactt gccaacatct
    52081 ccagatgcag ttgttattgt cgcaaccctt cgtgccctta agatgaatgg tggtgtggct
    52141 aaagacgctc tgactgaaga aaatgtagag gcagttcgtg caggttttgc taacttgaaa
    52201 cgccacgttg aaaatatccg taagttcggt attccagcag ttgtagctat taacgaattt
    52261 gtatctgata cagaagctga aattgcagtc ttaaaagaac tctgtgcctc aatcgatgta
    52321 ccagttgaat tggctagtgt ctgggctgat ggagcagaag gtggagtagc acttgccgaa
    52381 acagttgtta agacaattgc tgaaaatcca gctaactata aacgtttgta tgataatgac
    52441 ctttctgtcc aagaaaagat tgaaaaaatt gtcactgaaa tctatcgtgg tagcaaagtg
    52501 aactttgaga agaaatctca aacacaaatt gctcaaatcg ttcaaaacgg ttgggacaaa
    52561 ttgccaatct gtatggctaa aactcaatac agtttctcag acaatccaaa tgcgcttgga
    52621 gcaccagaaa actttgaaat taccattcgt gaattggtac caaaattagg tgcaggcttc
    52681 atcgttgcct taactggtga tgttatgacc atgccaggtc ttccaaaacg tccagcagct
    52741 ctcaacatgg atgttgaaag cgatggaact gtactaggct tgttctagtg gattgaaatt
    52801 gactttaagt gagtttggaa ataatatcca agctcatttt ttctcagact gcaagcagtt
    52861 catcaataag atttatactc ttcgaaaatc tcttcaaact acgtcagctt caccttgccg
    52921 taggtatatg atactgactc tgtcagttct atccacaacc tcaaaacagt gttttgagca
    52981 acctgcggct agcttcctag tttgctcttt gattttcatt gagtataagt agatagaaaa
    53041 gttatatact atctattgaa aatattataa atcagataca aagacaggtg aaaccttctg
    53101 tgttatacta gagatatgtt agatttgaaa gaatacggta tcgtcatgtg gccggaggag
    53161 aaagtcattt ctttccgtga gaaacttctc gcttggtatg atgaaaacaa aagagatttg
    53221 ccttggagga gaagtaaaaa tccttatcac atctgggtat ctgaaatcat gcttcagcag
    53281 accagggtgg atacagttat cccttactac gaaagattcc tggactggtt tccaactgtc
    53341 gaaagtctgg caactgcgtc tgaggagagt ttactgaaag cttgggaggg cttgggctat
    53401 tattctcgag ttcgcaatat gcaggctgca gcccagcaga ttatgactga ctttggtggc
    53461 caatttccaa atacctatga aggaatttcc agcttgaaag ggattggacc ttacacagca
    53521 ggagccattt ccagtattgc ttttaacttg cctgagccag ctgtagatgg taatgtcatg
    53581 cgggtcttgg cgcgtctgtt tgaagtcaac cacgatattg ggattccaag taatcgaaaa
    53641 atttttcagg caatgatgga gatcttgatt aatccggatc gtccgggtga ttttaatcaa
    53701 gccttgatgg acttagggtc tgatattgag tctcctgtaa atcccagacc tgaagaaagc
    53761 ccagtcaagg actttagtgc ggcatatcag aatggaacca tggaccgtta tccaattaaa
    53821 tctcctaaga aaaagccggt tcctatttat cttaaagcct tagttgtgaa aaattctcaa
    53881 ggacaatttt tacttgaaaa aaatgaaagc gaaaagctct tggcaggttt ttggcatttc
    53941 ccctttatag aagttgataa cttttcgcaa gaagagcagt ttgacctctt tcatcaggtt
    54001 gcggaagaaa gtgtgaactt tggtcccagt ccagaagaga gtttccagca ggactatgac
    54061 ctagatgttg attggcttga tgtttgtttt gatacagtcc agcatgtttt tagtcatcga
    54121 aaatggcatg tacagattgt agcaggtcag gtgagtgact tccatgattt ttcagatagg
    54181 gaagttcgtt ggctttcacc agaagaattc aagaattacc cacttgccaa accccaacaa
    54241 aaaatctggc aggcttatgc acaagccaac ttagacagta gccaagacta gctattgtgt
    54301 cttctgacta ttttttggta taatagtaga gaaaaaggtg aacatatgaa aaaaatacta
    54361 attgtagatg atgagaaacc aatctcggat attatcaagt ttaatatgac caaggaaggt
    54421 tatgaagttg taactgcttt taatggtcgt gaagcgctag agcaatttga agcagagcaa
    54481 ccagatatta ttattctgga tttgatgctt ccagaaattg atggtttaga agttgctaag
    54541 accattcgta agacaagcag tgtgcccatt cttatgcttt cagccaaaga tagtgaattt
    54601 gataaggtta tcggtttgga acttggggca gatgactatg taacgaaacc cttctccaat
    54661 cgtgagttgc aggcgcgtgt taaagctctt ctgcgtcgtt ctcaacctat gccagtagat
    54721 ggtcaggaag cagatagtaa acctcaacct atccaaattg gggatttaga aattgttcca
    54781 gacgcctacg tggctaaaaa atatggcgaa gaactagact taacccatcg tgaatttgag
    54841 cttttgtatc atttagcatc gcatacaggt caagtcatca cgcgcgaaca cttgcttgag
    54901 actgtctggg gttatgacta ttttggtgat gtccgtacag ttgatgtgac tgtacgacgt
    54961 ctgcgtgaga agattgaaga tacgcccagc cgaccagagt atatcttgac acgccgtggt
    55021 gtagggtatt acatgagaaa taatgcttga tttactgaaa caaaccattt ttaccagaga
    55081 ttttatcttt atcctgattt tgttaggttt catccttgtt gtgaccctct tattactgga
    55141 aaatagacgt gataatattc agttgaagca aatcaatcaa aaggttaaag atttgattgc
    55201 aggagattat tccaaggttc ttgatatgca aggtgggtct gaaatcacca atattaccaa
    55261 taatttgaat gacttgtcgg aggttattcg tctcactcag gaaaatctag aacaagagag
    55321 taagaggcta aatagtattc tgttttatat gacagatggg gttcttgcga ccaaccgtcg
    55381 gggtcagatt atcatgatta acgatacagc caagaagcaa ctggggttgg ttaaggaaga
    55441 tgttctgaat agaagcattt tggaattgct caagatagaa gaaaactatg aattgcgtga
    55501 tttgattacc caaagtccag aattgttgct agattcccaa gatatcaatg gtgaatattt
    55561 gaaccttcga gttcgctttg ccttgatacg tcgagagtct ggctttattt caggtttggt
    55621 ggctgttttg catgatacga cggagcagga gaaggaagaa cgcgaacgaa gactctttgt
    55681 ttccaatgtt agccatgagt tacggactcc tctgactagc gtaaaatcct atcttgaagc
    55741 cttggatgag ggggctttgt gtgaaactgt agcaccagac tttatcaagg tttctcttga
    55801 tgagaccaac cgtatgatgc gcatggtgac ggatctcctc catctttcac gtattgataa
    55861 tgctaccagt cacctagatg tggaactgat taacttcact gcttttatta cctttatcct
    55921 caatcgtttt gacaagatga aaggacagga aaaggagaaa aaatatgagt tggtgagaga
    55981 ttatcccatc aattctatct ggatggaaat tgatacagat aagatgacgc aggttgtcga
    56041 caatatttta aataatgcta ttaagtattc gccagatggg ggtaaaatca ctgtcagaat
    56101 gaagacaact gaagaccaga tgattttatc catttctgac cacggtttgg ggattcctaa
    56161 gcaggattta ccacgtatct ttgaccgttt ctatcgtgtg gatcgtgcta gaagtcgtgc
    56221 acaaggtggt acaggtctag gactgtctat cgctaaagaa attattaaac aacataaggg
    56281 ctttatttgg gccaagagtg aatacggcaa gggttcaacc tttaccattg tgctccctta
    56341 tgataaggat gcagtgaaag aagaagtatg ggaggatgaa gtagaagact agaatgagtg
    56401 aaataggctt taaatacagt attttagcgt cgggttccag tggaaattct ttttatctgg
    56461 aaacctcaaa aaagaagctt ttagtggatg caggcttgtc tggcaagaaa attaccagtc
    56521 tgctagctga aattaaccgc aagccagaag acctggatgc catcttgatt acccatgagc
    56581 attcagatca tatccatgga gtaggcgttt tggctcgcaa gtatggtatg gatctttatg
    56641 ccaatgaaaa gacctggcaa gctatggaaa atagtaaata tcttggcaag gtggattctt
    56701 cgcaaaagca tatttttgaa atgggtaaaa ccaaaacttt tggagatatc gacatcgaga
    56761 gttttggtgt aagccatgat gcagtcgcac cgcagttcta tcgctttatg aaggatgaca
    56821 agagttttgt ccttttgaca gatacaggtt atgtcagtga ccgtatggcg ggcattgtcg
    56881 aaaatgcgga tggctatctt atcgaggcca accatgatgt agagattttg cgatcaggtt
    56941 cttacgcttg gcgactcaaa caacgaatcc tatctgacct tggtcacctt tctaacgagg
    57001 acggtgctga agctatgatt cggacgctag gaaatcgtac taagaagatt taccttgggc
    57061 atttatctaa ggaaaacaat atcaaggaac tggctcatat gaccatggtc aatcagctgg
    57121 ctcaagctga tctgggagtc ggagtagact ttaaggttta tgatacctca ccagataccg
    57181 caacaccatt gacagagata tagaaagaac gctgagaagg tgttcttttt atattgactg
    57241 aacacctaaa aagtaataca atggtgttac cattaaaaaa gggagcacaa aagatgacta
    57301 ctattacatt aaaagtttct gaagctgata aaacatttat gaaagcaatg gctaagtttg
    57361 aaggagtttc cctttcggaa cttattcgca ccaaaactct tgaagcccta gaagatgaat
    57421 acgatgctcg tgtggcagat ttagcctatc aagagtattt agaagacttg gaaaaaggag
    57481 ttgaacccat tacttgggaa gaaatgatgc atgatttagg cttgaaggat gaataatttg
    57541 tataaattag ttccaacaag acgttttatc aagcaattga aaaaattgga ccgttatacg
    57601 cagaagctaa ttacaaacta tttacaaacc aatgttttgg aagacccaag acgacacgga
    57661 aaggctttgg ttggtaatcg cgttggtcaa tggcgctata gaattggtaa ttatcgagtt
    57721 attgtacaaa ttgtagatga tgaattagtc gttgctactc tagaagttgg tcatcggaga
    57781 gatatttatt aaattaaagc tgagtaataa cagtatagaa agtaaggaga gtaaaaattt
    57841 gaagaaaaaa tggttttttg tagattatta tgatacaaca attattttac ttgctttaat
    57901 ctctgttatt ctggtattac ttggatttgc tgagatgatt gatttggaca atccgcctta
    57961 tagtattatt gatttagtaa tctggggtgt ttttgtaatt gattatagtt ggcgcttttt
    58021 tattactaaa agaaaatggc gctttattct tgaaaatatt tttgatttat tggctattct
    58081 ccctttaaat gctattttta cagtgtttcg attagggcgt atctttcgtt tagctaaact
    58141 aacaaaatta ctgaaactga ctcgtttact tagaataatt ggacttacag gtaaattaga
    58201 aagaaaaatt agtagattct tacggacaaa tggcctgatt tatatcttgt atgttaatat
    58261 ctttattgtt ctagtaggga gttcgatttt atccgttgtt gaagaaaaat ccttctcaga
    58321 tagtctttgg tgggctcttg tgacagtaac tactgttgga tatggggata ttgttcctgc
    58381 ttccattttt gggaaatggc tagcagtttt actgatgctt gtcggtattg gaacaatagg
    58441 gatgttaaca agtgctttga cgaacttttt tgtaaaggat aatccagatg aacagataaa
    58501 acttgataaa ctccaagatg aattatctag tcagagaata ttactagaga aacaatctaa
    58561 aaagatagaa gaactacata aaatgataca agatttgatt gaaaaaacat aataaaaata
    58621 aagatgagac aaagtttgag ctgaggagaa atcaagtaag ttttgacaca atagaacgca
    58681 tattatcagg tataaaaact tgatactatg cgttttatag agaaataaaa taaaatctga
    58741 acaaatcaat taggaattta aagcatttta taac
//
LOCUS       DAVHTH010000006        56724 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.006, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000006 DAVHTH010000000
VERSION     DAVHTH010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 56724)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56724)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56724
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.006"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            <1..780
                     /locus_tag="VVR63_000368"
     CDS             <1..780
                     /locus_tag="VVR63_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HEU6128423.1"
                     /translation="EQFQHDNRQVDLKILARHIHRLKKKQSDWKVQYTRCLDIIFPEL
                     DKIVGKHSEYTYQLLTRYPNPQKRIEAGFDKLIEIKRLTASKIQDILSVAPRSIETTS
                     PAREFEIIEIIKHYKRLIDKAETCVNDLIAEFNSVITTVTGIGGRLGAVILAEIRNIH
                     AFDNPAQLQAFAGLDSSIYQSGQIDLAGRMIKRGSPHLRWALIQAAKACARFSPAFKA
                     YLKTKLEQGKHYNVAIIHLAKKLIRTLFYILKKSCHLTNKK"
     gene            complement(979..2868)
                     /locus_tag="VVR63_000369"
     CDS             complement(979..2868)
                     /locus_tag="VVR63_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HEU6128424.1"
                     /translation="MKKTFFLLVLGLFCLLPLSVFAIDFKINSYQGDLYIHADNTAEF
                     RQKIVYQFEEDFKGQIVGLGRAGKMPSGFDIDPHPKVQAAKNGAELADVTSEVTEEAD
                     GYTVRVYNPGQEGDIVEVDLVWNLKNLLFLYDDIAELNWQPLTDSSESIEKFEFHVRG
                     DKGAEKLFFHTGKLFREGTIEKSNLDYTIRLDNLPAKRGVELHAYWPRTDFASARDQG
                     LKGNRLEEFNKIEDSIVREKEQSKQLLTWVLPSILSISLLLSVCFYFIYRRKTTPSVK
                     YAKNHRLYEPPMELEPMVLSEAVYSTSLEEVSPLVKGAGKFTFDQLIQATLLDVIDRG
                     NVSIISEGDAVGLRLVKEDGLSSFERDCLNLAFSGKKEETLSNLFADYKVSDSLYRRA
                     KVSDEKRIQARGLQLKSSFEEVLNQMQEGVRKRVSFWGLPDYYRPLTGLEKTLQVGMG
                     VLTILPLFIGFGLFLYSLDVHGYLYLPLPILGFLGLVLSVFYYWKLRLDNRDGVLNEA
                     GAEVYYLWTSFENMLREIARLDKAELESIVVWNRLLVYATLFGYADKVSHLMKVHQIQ
                     VENPDINLYVAYGWHSMFYHSSAQMSHYASVANTASTYSVSSGSGSSGGGFSGGGGGG
                     SIGAF"
     gene            3006..4571
                     /locus_tag="VVR63_000370"
     CDS             3006..4571
                     /locus_tag="VVR63_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEU6128425.1"
                     /translation="MRKIYLSIFTSLLLMLGLVNVAQADEYLRIGMEAAYAPFNWTQD
                     DDSNGAVKIDGTNQYANGYDVQIAKKIAKDLGKEPLVVKTKWEGLVPALTSGKIDMII
                     AGMSPTAERKQEIAFSSSYYTSEPVLLVKKDSAYASAKSLDDFNGAKITSQQGVYLYD
                     LIAQIPGAKKETAMGDFAQMRQALEAGVIDAYVSERPEALTAEAANSKFKMIQVEPGF
                     KTGEEDTAIAIGLRKNDNRISQINASIETISKDDQVALMDRMIKEQPAEATTTEETSS
                     SFFSQVAKILSENWQQLLRGAGITLLISIVGTIIGLIIGLAIGVFRTAPLSENKAIYG
                     LQKLVGWVLNVYIEIFRGTPMIVQSMVIYYGTAQAFGINLDRTLAAIFIVSINTGAYM
                     TEIVRGGILAVDKGQFEAATALGMTHNQTMRKIVLPQVVRNILPATGNEFVINIKDTS
                     VLNVISVVELYFSGNTVATQTYQYFQTFTIIAVIYFVLTFTVTRILRFIERRMDMDTY
                     TTGANQMQTEDLK"
     gene            4571..5311
                     /locus_tag="VVR63_000371"
     CDS             4571..5311
                     /locus_tag="VVR63_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU6128426.1"
                     /translation="MTQAILEIKHLKKSYGQNEVLKDISLTVHKGEVISIIGSSGSGK
                     STFLRSINLLETPTDGQILYHGQNVLEKGYDLTQYREKLGMVFQSFNLFENLNVLENT
                     IVAQTTVLKRERTEAEKIAKENLEKVGMGERYWQAKPKQLSGGQKQRVAIARALSMNP
                     DAILFDEPTSALDPEMVGEVLKIMQDLAQEGLTMIVVTHEMEFARDVSHRVIFMDKGV
                     IAEEGKPEDLFTNPKEDRTKEFLQRYLK"
     gene            complement(5420..5635)
                     /locus_tag="VVR63_000372"
     CDS             complement(5420..5635)
                     /locus_tag="VVR63_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6128427.1"
                     /translation="MAKSNFEKVESVVGWVRDKKITGYRISKETNAREMSIIALAQGR
                     AKVKNISFETALGLIDFYEKNYEKFED"
     gene            complement(6506..7756)
                     /gene="ilvA"
                     /locus_tag="VVR63_000373"
     CDS             complement(6506..7756)
                     /gene="ilvA"
                     /locus_tag="VVR63_000373"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase IlvA"
                     /protein_id="HEU6128428.1"
                     /translation="MLSSKDIIKAHKVLNGVVVNTPLDYDHYLSEKYGAKIYLKKENA
                     QRVRSFKIRGAYYAISQLSKEERERGVVCASAGNHAQGVAYTCNEMKIPATIFMPITT
                     PQQKIGQVRFFGGDFVTIKLVGDTFDASAKAAQEFTVSENRTFIDPFDDAHVQAGQGT
                     VAYEILEEARKESIDFDAVLVPVGGGGLIAGVSTYIKETSPEIEVIGVEANGARSMKA
                     AFEAGGPVKLKEIDKFADGIAVQKVGQLTYEATRQHIQTLVGVDEGLISETLIDLYSK
                     QGIVAEPAGAASIASLEVLAEYIKGKTICCIISGGNNDINRMPEMEERALIYDGIKHY
                     FVVNFPQRPGALREFVNDILGPNDDITRFEYIKRASKGTGPVLIGIALADKHDYAGLI
                     RRMEGFDPAYINLNGNETLYNMLV"
     gene            complement(7806..8162)
                     /locus_tag="VVR63_000374"
     CDS             complement(7806..8162)
                     /locus_tag="VVR63_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HEU6128429.1"
                     /translation="MNITNLFSIKTGCDETDRQLQKLFFQLDLQLGELTDQLRKLDSN
                     FVPRSQFVDTLDLNDVEYKEILNYFIFHRNDSEESLVEWLYDWISTNRYELPKEFSIR
                     MAHKYHESVTEIFGDE"
     gene            complement(8400..8636)
                     /locus_tag="VVR63_000375"
     CDS             complement(8400..8636)
                     /locus_tag="VVR63_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6128430.1"
                     /translation="MLADQNKADWSYDENAVINIYDDANFEDGRLHMTFEQFFKLAQI
                     AREEGLEIHSPFERAGATKSARYIAKWILRNKKY"
     gene            complement(8743..9765)
                     /gene="ilvC"
                     /locus_tag="VVR63_000376"
     CDS             complement(8743..9765)
                     /gene="ilvC"
                     /locus_tag="VVR63_000376"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HEU6128431.1"
                     /translation="MTVQMEYEKDVKVAALDGKKIAVIGYGSQGHAHAQNLRDSGRDV
                     IIGVRPGKSFDKAKEDGFDTYTVAEATKLADVIMILAPDEIQQELYEAEIAPNLEAGN
                     AVGFAHGFNIHFEFIKVPADVDVFMCAPKGPGHLVRRTYEEGFGVPALYAVYQDATGN
                     AKNIAMDWCKGVGAARVGLLETTYKEETEEDLFGEQAVLCGGLTALIEAGFEVLTEAG
                     YAPELAYFEVLHEMKLIVDLIYEGGFKKMRQSISNTAEYGDYVSGPRVITEQVKENMK
                     AVLADIQNGKFANDFVNDYKAGRPKLTAYREQAANLEIEKVGAELRKAMPFVGKNDDD
                     AFKIYN"
     gene            complement(9831..10307)
                     /gene="ilvN"
                     /locus_tag="VVR63_000377"
     CDS             complement(9831..10307)
                     /gene="ilvN"
                     /locus_tag="VVR63_000377"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HEU6128432.1"
                     /translation="MRRMLTAKLQNRSGVLNRFTGVLSRRQVNIESISVGATEDPNVS
                     RITIIIDVASHDEVEQIIKQLNRQIDVIRIRDITDKPHLEREVILVKMSAPAEKRAEI
                     LAIIQPFRATVVDVAPSSITIQMTGNAEKSEALLRVIRPYGIRNIARTGATGFTRD"
     gene            complement(10300..12000)
                     /locus_tag="VVR63_000378"
     CDS             complement(10300..12000)
                     /locus_tag="VVR63_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HEU6128433.1"
                     /translation="MEKISLESPKTGSDLVLETLRDLGVDTIFGYPGGAVLPFYDAIY
                     NFKGIRHILGRHEQGCLHEAEGYAKSTGKLGVAVVTSGPGATNAITGIADAMSDSVPL
                     LVFTGQVARAGIGKDAFQEADIVGITMPITKYNYQVRETADIPRIITEAVHIATTGRP
                     GPVVIDLPKDISALETDFIYSPEVNLPSYQPTLEPNDMQIKKILKQLSKAKKPVLLAG
                     GGISYAEAATELNEFAERYQIPVVTSLLGQGTIATSHPLFLGMGGMHGSFAANIAMTE
                     ADFMISIGSRFDDRLTGNPKTFAKNAKVAHIDIDPAEIGKIISADIPVVGDAKKALQM
                     LLAEPTVHNNTEKWIEKVTKDKNRVRSYDKKERVVQPQAVIERIGELTNGDAIVVTDV
                     GQHQMWTAQYYPYQNERQLVTSGGLGTMGFGIPAAIGAKIANPDKEVVLFVGDGGFQM
                     TNQELAILNIYKVPIKVVMLNNHSLGMVRQWQESFYEGRTSESVFDTLPDFQLMAQAY
                     GIKNYKFDNPETLAQDLEVITEDVPMLIEVDISRKEQVLPMVPAGKSNHEMLGVQFHA
                     "
     gene            complement(12200..13867)
                     /locus_tag="VVR63_000379"
     CDS             complement(12200..13867)
                     /locus_tag="VVR63_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HEU6128434.1"
                     /translation="MSKITTSLFQEMVQAASTRLNKQAEYVNSLNVFPVPDGDTGTNM
                     GMTIENGAKEVADKPASTVGEVASILAKGLLMGARGNSGVITSQLFRGFSQAIKDKDE
                     LTGQDLALAFQSGVEVAYKAVMKPVEGTILTVSRGAAIGAKKKAEQTDDTVEVMRAAL
                     EGAKTALAKTPDMLPVLKEVGVVDSGGQGLVFIYEGFLSALTGEYIASEDFVATPANM
                     SEMINVEHHKSVAGHVATEDITFGYCTEIMVALKQGPTYAKDFDYDEFRNYLDELGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLVKVKVDNMRNQHEAQVEKEATQVIKS
                     AEEKEYALIAVVAGKGLADIFCSQGVDYVIEGGQTMNPSTEDFIKAVEQVNARNIIFL
                     PNNKNIFMAAQSAAEVLEQPAVVVEARTLPQGMTSLLAFDPSKSIEENQERMTAALSD
                     VVSGSVTTAVRDTTIDGLEIHENDNLGMVDGKILVSNPDMHQTLTETLKHMLDEDSEI
                     VTFYVGEDGSEELANEIAQEIVEEFEDVEVEIHQGQQPVYPYLFSVE"
     gene            complement(13870..14235)
                     /locus_tag="VVR63_000380"
     CDS             complement(13870..14235)
                     /locus_tag="VVR63_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEU6128435.1"
                     /translation="MTVKINTKDGQIELTDEVIATVVGGAATEIFGVVGMASKNALKD
                     NFQALLGKENYSKGVVVKAAEDGSIAVDVYTVLSYGTKISEVSKNIQERVAFSLENQL
                     GITAQTVNVYIQNIKVVGE"
     gene            complement(14392..14580)
                     /locus_tag="VVR63_000381"
     CDS             complement(14392..14580)
                     /locus_tag="VVR63_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HEU6128436.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRAVKPNLQKVTVLIDGKP
                     KKVWASARALKSGKVERV"
     gene            complement(14696..15181)
                     /locus_tag="VVR63_000382"
     CDS             complement(14696..15181)
                     /locus_tag="VVR63_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HEU6128437.1"
                     /translation="MKEEKKAIVLGADNAYMDKVETTIKSLCVHHYNLKFYVFNDDLP
                     REWFQLMEKRLETLNSEIVNVQIDSSILKGYRLPFEGLSYAAFFRYFIPKYVSESRVL
                     YLDSDIVVRKSIDELWDLDLTAIPLAAVRDDFYTHNFNSGVLLINNGMWRAENVTQDL
                     I"
     gene            complement(15450..16994)
                     /locus_tag="VVR63_000383"
     CDS             complement(15450..16994)
                     /locus_tag="VVR63_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HEU6128438.1"
                     /translation="MNIQEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKTGTFAKSDWMDIEKQRGISVTSSVMQFDYDGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRGIPVFTFMNKLDRDGREPLDLLQELEEILG
                     IASYPMNWPIGMGKAFEGLYDLYNQRLELYKGDERFASLEDGDKLFGSNPFYEQVKDD
                     IELLNEAGNEFSEEAILAGELTPVFFGSALTNFGVQTFLEIFLKFAPEPHGHKKTDGE
                     IVDPYDKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFERGMSVNLPRTGKGAKLSNV
                     TQFMAESRENVINAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVS
                     AKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VVMSPMGKKTVRWIKPEDLDERMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     ELEEKM"
     gene            17207..17509
                     /gene="gatC"
                     /locus_tag="VVR63_000384"
     CDS             17207..17509
                     /gene="gatC"
                     /locus_tag="VVR63_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HEU6128439.1"
                     /translation="MKITQEEVTHVANLSKLRFSEEETAAFATTLSKIVDMVELLGEV
                     DTTGVAPTTTMADRKTVLRPDVAEEGTDRDRLFKNVPEQDNYYIKVPAILDDGGDA"
     gene            17509..18975
                     /gene="gatA"
                     /locus_tag="VVR63_000385"
     CDS             17509..18975
                     /gene="gatA"
                     /locus_tag="VVR63_000385"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HEU6128440.1"
                     /translation="MTFNNKTIEELHNLLVSKEISATELTQATLENIKSREEALNSFV
                     TIAEEQALVQAKAIDEAGIDADNVLSGIPLAVKDNISTDGILTTAASKMLYNYEPIFD
                     ATAVANAKTKGMIVVGKTNMDEFAMGGSGETSHYGATKNAWDHSKVPGGSSSGSAAAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGIVGLKPTYGTVSRFGLIAFGSSLDQIGPFAPTV
                     KENALLLNAIASEDAKDSTSAPVRIADFTSKIGQDIKGMKIALPKEYLGEGIDPEVKE
                     TILNAAKHFEKLGAIVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRAEDA
                     TNLDEIYVNSRSQGFGEEVKRRIMLGTFSLSSGYYDAYYKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPSVAYDLDSLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFSQGLPVG
                     LQLIGPKHSEETIYQVAAAFEATTGYHKQQPVIFGGDN"
     gene            18975..20417
                     /gene="gatB"
                     /locus_tag="VVR63_000386"
     CDS             18975..20417
                     /gene="gatB"
                     /locus_tag="VVR63_000386"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HEU6128441.1"
                     /translation="MNFETVIGLEVHVELNTNSKIFSPTSAHFGNDQNANTNVIDWSF
                     PGVLPVLNKGVVDAGIKAALALNMDIHKKMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIEVELEDGTTKKIGIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEVIQYAGISDVKMEEGSMRVDANISLRPYGQEKFGTKTELKNLNS
                     FSNVRKGLEYEVQRQAEILRSGGQIRQETRRYDEANKATILMRVKEGAADYRYFPEPD
                     LPLFEISDEWIEEMRTELPEFPKERRARYVSDLGLSDYDASQLTANKVTSNFFEKAVA
                     LGGDAKQVSNWLQGEVAQFLNAEGKTLEQIELTPENLVEMITIIEDGTISSKIAKKVF
                     VHLAKNGGGAREYVEKAGMVQISDPAILIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMRATKGQANPQVALKLLAQELAKLKEN"
     gene            20546..21106
                     /gene="efp"
                     /locus_tag="VVR63_000387"
     CDS             20546..21106
                     /gene="efp"
                     /locus_tag="VVR63_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HEU6128442.1"
                     /translation="MIEASKLKAGMTFETADGKLIRVLEASHHKPGKGNTIMRMKLRD
                     VRTGSTFDTSYRPEEKFEQAIIETVPAQYLYKMDDTAYFMNTETYDQYEIPVVNVENE
                     LLYILENSDVKIQFYGTEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATMETGLV
                     VNVPDFIEAGQKLVINTAEGTYVSRA"
     gene            21128..21517
                     /locus_tag="VVR63_000388"
     CDS             21128..21517
                     /locus_tag="VVR63_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEU6128443.1"
                     /translation="MGIEEQLGEIVIAPRVLEKIIAIATAKVEGVHSFSNRSVSDTLS
                     KLSLGRGIYLKNVDEELTADIYLYLEYGVKVPKVAVAIQKAVKDAVRNMADVELAAIN
                     IHVAGIVPDKTPKPELKDLFDEDFLND"
     gene            21510..21932
                     /gene="nusB"
                     /locus_tag="VVR63_000389"
     CDS             21510..21932
                     /gene="nusB"
                     /locus_tag="VVR63_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000203663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HEU6128444.1"
                     /translation="MTSPLLESRRQLRKCAFQALMSLEFGTDVETACRFAYTHDREDT
                     DVQLPAFLIDLVSGVQAKKEELDKQITQHLKAGWTIERLTLVERNLLRLGVFEITSFD
                     TPQLVAVNEAIELAKDFSDQKSARFINGLLSQFVTEEQ"
     gene            complement(21979..22356)
                     /locus_tag="VVR63_000390"
     CDS             complement(21979..22356)
                     /locus_tag="VVR63_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU6128445.1"
                     /translation="MVLSNGQPTFLSTILSFVLLVIIGPVFEETLDRGYFMNTFFPKS
                     KYYLDVILSGLIFGISHLILSHRDPISLLYYSLIGFFFALVYRSTDNLRLTILCHSFF
                     NFLNHAKPIWIFVYNYIYYHFFR"
     gene            complement(22719..22904)
                     /gene="briC"
                     /locus_tag="VVR63_000391"
     CDS             complement(22719..22904)
                     /gene="briC"
                     /locus_tag="VVR63_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm-regulating peptide BriC"
                     /protein_id="HEU6128446.1"
                     /translation="MTGTNTFTVLSTEDLEQTSGGLAVWEDGYSRWLYYREFAPYMRQ
                     GALNSYIDAWKYGFRAG"
     gene            complement(23167..23934)
                     /locus_tag="VVR63_000392"
     CDS             complement(23167..23934)
                     /locus_tag="VVR63_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HEU6128447.1"
                     /translation="MNIAKIVREAREQSRLTTLDFATGIFDEFIQLHGDRSFRDDGAV
                     VGGIGWLGDQAVTVVGIQKGKSLQDNLKRNFGQPHPEGYRKALRLMKQAEKFGRPVVT
                     FINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADRV
                     WMLENSIYAILSPEGFASILWKDGTRAMEAAELMKITSHELLEMDVVDKVISEVGLSS
                     KELIKSVKKELQTELARLSQKPLEELLEERYQRFRKY"
     gene            complement(23931..24797)
                     /locus_tag="VVR63_000393"
     CDS             complement(23931..24797)
                     /locus_tag="VVR63_000393"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001173351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HEU6128448.1"
                     /translation="MALFSKKDKYIRINPNRSVREKPQAKPEVPDELFSQCPGCKHTI
                     YQKDLGSERICPHCSYTFRISAQERLALTIDMGTFKELFTGIESKDPLHFPGYQKKLA
                     SMREKTGLHEAVVTGTALIKGQTVALGIMDSNFIMASMGTVVGEKITRLFEYATVEKL
                     PVVLFTASGGARMQEGIMSLMQMAKISAAVKRHSNAGLFYLTILTDPTTGGVTASFAM
                     EGDIILAEPQSLVGFAGRRVIENTVRESLPEDFQKAEFLLEHGFVDAIVKRRDLPDTI
                     ASLVRLHGGSPR"
     gene            complement(24834..26201)
                     /gene="accC"
                     /locus_tag="VVR63_000394"
     CDS             complement(24834..26201)
                     /gene="accC"
                     /locus_tag="VVR63_000394"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000488661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HEU6128449.1"
                     /translation="MFRKILIANRGEIAVRIIRAARELGIATVAVYSTADKEALHTLL
                     ADEAVCIGPGKATESYLNINAVLSAAVLTEAEAIHPGFGFLSENSKFATMCEEVGIKF
                     IGPSGHVMDMMGDKINARAQMIKAGVPVIPGSDGEVHNSEEALIVAEKIGYPVMLKAS
                     AGGGGKGIRKVEKPDDLVSAFETASSEAKANYGNGAMYIERVIYPARHIEVQILGDEH
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGKTLRHEIGAAAVRAAEFVGYENAGTIEF
                     LLDEASSNFYFMEMNTRVQVEHPVTEFVSGVDIVKEQICIAAGQPLSVKQEDIVLRGH
                     AIECRINAENPAFNFAPSPGKITNLYLPSGGVGLRVDSAVYPGYTIPPYYDSMIAKII
                     VHGENRFDALMKMQRALYELEIEGVQTNADFQLDLISDRNVIAGDYDTSFLMETFLPK
                     YQEKE"
     gene            complement(26213..26635)
                     /gene="fabZ"
                     /locus_tag="VVR63_000395"
     CDS             complement(26213..26635)
                     /gene="fabZ"
                     /locus_tag="VVR63_000395"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HEU6128450.1"
                     /translation="MIDIQGIKEALPHRYPMLLVDRVLEVSEDTIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKPENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTATFVKRRGTIAVVEAKAEVDGKLAASGTLTFAIGN"
     gene            complement(26632..27117)
                     /locus_tag="VVR63_000396"
     CDS             complement(26632..27117)
                     /locus_tag="VVR63_000396"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HEU6128451.1"
                     /translation="MNLNDIKDLMTQFDQSSLREFSYKNGTDELQFSKNEARPVPEVA
                     TQVAPAPVLATPSPVAPTSAPAETVAEEVPAPAEASVATEGNLVESPLVGVVYLAAGP
                     DKPAFVTVGDSVKKGQTLVIIEAMKVMNEIPAPKDGVVTEILVSNEEMVEFGKGLVRI
                     K"
     gene            complement(27120..28355)
                     /gene="fabF"
                     /locus_tag="VVR63_000397"
     CDS             complement(27120..28355)
                     /gene="fabF"
                     /locus_tag="VVR63_000397"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HEU6128452.1"
                     /translation="MKLNRVVVTGYGVTSPIGNTPEEFWNSLATGKIGIGGITKFDHS
                     DFDVHNAAEIQDFPFDKYFVKKDTNRFDNYSLYALYAAQEAVNHANLDVEALNRDRFG
                     VIVASGIGGIKEIEDQVLRLHEKGPKRVKPMTLPKALPNMASGNVAMRFGANGVCKSI
                     NTACSSSNDAIGDAFRSIKFGFQDVMLVGGTEASITPFAIAGFQALTALSTTEDPTRA
                     SIPFDKDRNGFVMGEGSGMLVLESLEHAEKRGATILAEVVGYGNTCDAYHMTSPHPEG
                     QGAIKAIKLALEEAEISPEQVAYVNAHGTSTPANEKGESGAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIVTIEAMRHNFVPMTAGTSEVSDYIEANVVYGQGLEKEIPYAISN
                     TFGFGGHNAVLAFKRWENR"
     gene            complement(28377..29108)
                     /gene="fabG"
                     /locus_tag="VVR63_000398"
     CDS             complement(28377..29108)
                     /gene="fabG"
                     /locus_tag="VVR63_000398"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HEU6128453.1"
                     /translation="MKLEHKNIFITGSSRGIGLAIAHKFAQAGANIVLNSRGAISEEL
                     LAEFSNYGIKVVPISGDVSDFADAKRMIDQAIAELGSVDVLVNNAGITQDTLMLKMTE
                     ADFEKVLKVNLTGAFNMTQSVLKPMMKAREGAIINMSSVVGLMGNIGQANYAASKAGL
                     IGFTKSVAREVASRNIRVNVIAPGMIESDMTAILSDKIKEATLAQIPMKEFGQAEQVA
                     DLTVFLAGQDYLTGQVIAIDGGLSM"
     gene            complement(29142..30062)
                     /gene="fabD"
                     /locus_tag="VVR63_000399"
     CDS             complement(29142..30062)
                     /gene="fabD"
                     /locus_tag="VVR63_000399"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HEU6128454.1"
                     /translation="MTKTAFLFAGQGAQYLGMGRDFYDQYPIVKETIDRASQVLGYDL
                     RYLIDTEEDKLNQTRYTQPAILATSVAIYRLLQEKGYQPDMVAGLSLGEYSALVASGA
                     LDFEDAVALVAKRGAYMEEAAPADSGKMVAVLNTPVEVIEEACQKASELGVVTPANYN
                     TPAQIVIAGEVVAVDRAVELLQEAGAKRLIPLKVSGPFHTALLEPASQKLAETLAQVS
                     FSDFTCPLVGNTEAAVMQKEDIAQLLTRQVKEPVRFYESIGVMQEAGISNFIEIGPGK
                     VLSGFVKKIDRTAHLAHVEDQASLVALLEK"
     gene            complement(30055..31029)
                     /gene="fabK"
                     /locus_tag="VVR63_000400"
     CDS             complement(30055..31029)
                     /gene="fabK"
                     /locus_tag="VVR63_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HEU6128455.1"
                     /translation="MKTRITELLKIDYPIFQGGMAWVADGDLAGAVSKAGGLGIIGGG
                     NAPKEVVKANIDKIKSLTDKPFGVNIMLLSPFVEDIVDLVIEEGVKVVTTGAGNPSKY
                     MERFHEAGIIVIPVVPSVALAKRMEKIGADAVIAEGMEAGGHIGKLTTMTLVRQVATA
                     VSIPVIAAGGIADGEGAAAGFMLGAEAVQVGTRFVVAKESNAHPNYKEKILKARDIDT
                     TISAQHFGHAVRAIKNQLTRDFELAEKDAFKQEDPDLEIFEQMGAGALAKAVVHGDVD
                     GGSVMAGQIAGLVSKEETAEEILKDLYYGAAKKIQEEASRWAGVVRND"
     gene            complement(31148..31372)
                     /locus_tag="VVR63_000401"
     CDS             complement(31148..31372)
                     /locus_tag="VVR63_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEU6128456.1"
                     /translation="MAVFEKVQEIIVEELGKDASEVTLESTFDDLDADSLDLFQVISE
                     IEDAFDIQIEAENDLKTVGDLVAYVEEQAK"
     gene            complement(31432..32406)
                     /locus_tag="VVR63_000402"
     CDS             complement(31432..32406)
                     /locus_tag="VVR63_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HEU6128457.1"
                     /translation="MAFAKISQVAHYVPEQVVTNHDLAQIMDTNDEWISSRTGIRQRH
                     ISRTESTSDLATEVAKKLMAKAGITGEELDFIILATITPNSMMPSTAARVQANIGANK
                     AFAFDLTAACSGFVFALSTAEKFIASGRFQKGLVIGSETLSKAVDWSDRSTAVLFGDG
                     AGGVLLEASEQEHFLAESLNSDGSRSECLTYGHSGLHSPFSDQESADSFLKMDGRTVF
                     DFAIRDVAKSIKQTIDESPIEVTDLDYLLLHQANDRILDKMARKIGVDRAKLPANMME
                     YGNTSAASIPILLSECVEQGLIPLDGSQTVLLSGFGGGLTWGTLILTI"
     gene            complement(32406..32840)
                     /locus_tag="VVR63_000403"
     CDS             complement(32406..32840)
                     /locus_tag="VVR63_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEU6128458.1"
                     /translation="MDYQRINEYLTSIFNNVLVIEEVNLRGSRFKDISIKEMHTIDVI
                     GKAPDVTPSQVSKELMVTLGTVTTSLNNLERKGYIERVRSEQDRRVVHLHLTKKGRLI
                     HRLHKRFHKAMVEKIIDGMSEEEIAVMGKGLTNLYQFLEDLK"
     gene            complement(32934..33719)
                     /locus_tag="VVR63_000404"
     CDS             complement(32934..33719)
                     /locus_tag="VVR63_000404"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HEU6128459.1"
                     /translation="MEHIIYQLEEDLAILTLNRPEVANGFHIPMCEEILEALTLAEEN
                     PAVHFILINANGKVFSVGGDLVEMKRAVDEDDIPSLTKIAELVNTISYKIKQIAKPVL
                     MEVDGAVAGAAANMAVAADFCLATDKAKFIQAFVGVGLAPDAGGIHLLSRSIGVTRAA
                     QLAMTGEALTAEKALEWGLVYRVSEAEKLEKTREQLLKKLRRASSNSYAAIKKLVWES
                     QFKDWQGYATLELNLQKSLAQTEDFKEGVRAHSERRRPKFTGK"
     gene            34044..35408
                     /locus_tag="VVR63_000405"
     CDS             34044..35408
                     /locus_tag="VVR63_000405"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HEU6128460.1"
                     /translation="MKVVKFGGSSLASASQLEKVLNIVKSDSERRFIVVSAPGKRNAE
                     DTKVTDALIKYYRDYVAGNDISKSQSWIIDRYAAMVSELGLKPAVLEKISKSIHALAA
                     LPIEENEFLYDTFLAAGENNNAKLIAAYFNQNGIDARYMHPREAGIVVTSEPGHARII
                     PSSYDKIEELTTTNEVLVIPGFFGVTKENQICTFSRGGSDITGSIIAAGVKADLYENF
                     TDVDGIFAAHPGIIHQPHSIPELTYREMRELAYAGFSVLHDEALLPAYRGKIPLVIKN
                     TNNPDHPGTRIVLKHSNDEFPVVGIAGDSGFVSINMSKYLMNREVGFGRKVLQILEEL
                     NIGWEHMPTGIDDLSIILRSRQLTPIKEEEILRQLVQKAKVDHAEIEHDLSIIMIVGE
                     KMKSHIGVTATATRALSENKINIQMMSQGSSEVSIMFVVNKDQEKAAIKALYNAFFGE
                     SKED"
     gene            35411..35782
                     /locus_tag="VVR63_000406"
     CDS             35411..35782
                     /locus_tag="VVR63_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HEU6128461.1"
                     /translation="MAQSLNKTVLLSTTGTSYLSIAGKVGKFLVGDQALEFYPDVNVE
                     QFIQIPWSHINQIGANVTGRKISRHFEVFTDKGKFLFASKDSGAILKIARKKLGNDKV
                     VKLPTLIQTISQKFKNLFAKK"
     gene            35996..37270
                     /gene="serS"
                     /locus_tag="VVR63_000407"
     CDS             35996..37270
                     /gene="serS"
                     /locus_tag="VVR63_000407"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HEU6128462.1"
                     /translation="MLDIKRIRTDFEAVTEKLATRGVDAAVLNEMKEIDAKRRNILVK
                     VETLKAERNTVSAEIAQAKRNKENTDDKIAAMQNLSAEVKALDAELAEIDAKLTEFTT
                     TLPNIPADSVPVGADEDDNVEVRRWGTPREFDFEPKAHWDLGEDLGILDWERGGKVTG
                     ARFLFYKGLGARLERAIYNFMLDEHGKEGYTEVITPYIVNHDSMFGTGQYPKFKEDTF
                     ELSDTNFVLIPTAEVPLANYYRDEILDGKDLPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPEESYEELEKMTANAENILQKLNLPYRVVALSTGDMGFSAAKTY
                     DLEVWIPAQNNYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEALRPYMGGAEVIKP"
     gene            complement(37295..38194)
                     /locus_tag="VVR63_000408"
     CDS             complement(37295..38194)
                     /locus_tag="VVR63_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000735961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HEU6128463.1"
                     /translation="MKKLPLVFSGCLLGLAGAGNLILDTLPVLSHLFSLTGLVLWIYF
                     LILHLFNWKETKQELTKPPLLSGMATFPMAGMILSTYVFRVFSYLPLVAQGIWWFSFL
                     LDLTLIAGFTIKFACPGRRVHATPSWTVLYVGIAVAALTYPLVGIIEIAYATLSFGFL
                     LTFYLYPLIYSDLKKHPLPLALLGQEGIYCAPFSLLLASLVRVGGTSLPTWVLIVMIL
                     ASQSFFFFVLTRLPNILKQGFQPAFSALTFPTIITATSLKMAQGILKLPFLDYLVLAE
                     TIICLTILFFVLGDYLIWLRKKV"
     gene            complement(38304..38852)
                     /locus_tag="VVR63_000409"
     CDS             complement(38304..38852)
                     /locus_tag="VVR63_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000206764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HEU6128464.1"
                     /translation="MTTFTIHTVESAPAEVKEILETVEKDNNGYIPNLIGLLANAPTV
                     LEAYQIVSSIHRRNSLTPVEREVVQITAAVTNGCAFCVAGHTAFSIKQIQMNDDLIQA
                     LRNRTPIETDPKLDTLAKFTLAVINTKGRVGDEALSEFLEAGYTQQNALDVVFGVSLA
                     ILCNYANNLANTPINPELQPYA"
     gene            complement(39070..40392)
                     /locus_tag="VVR63_000410"
     CDS             complement(39070..40392)
                     /locus_tag="VVR63_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HEU6128465.1"
                     /translation="MLELLKSIDAFAWGPPLLILLVGTGIYLTMRLGLLQVLRLPKAF
                     QLIFIQDKGHGDVSSFAALCTALASTVGTGNIIGVATAIKVGGPGALFWMWMAAFFGM
                     ATKYAEGLLAIKYRTKDDHGAVAGGPMHYILLGMGEKWRPLAVLFAVAGVLVALLGIG
                     TFTQVNSITESIQNTTTISPAITALVLSVFVAIAVFGGLKSISKVSTTVVPFMALIYI
                     LGTLTVIFFNIGKIPGTIALVFTSAFSPLAAVGGFAGASVRMAIQNGVARGVFSNESG
                     LGSAPIAAAAAKTNEPVEQGLISMTGTFIDTLIICTLTGLTILVTGVWSGDLNGVALT
                     QSAFSTVFSHFGPALLTIFLVLFAFTTILGWNYYGERCFEFLFGARFIWLYRVFFVLM
                     VLLGGFIELDMVWIIADIVNALMALPNLIALLVLSPVVIAETKKYFNK"
     regulatory      complement(40483..40571)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            complement(40735..43071)
                     /locus_tag="VVR63_000411"
     CDS             complement(40735..43071)
                     /locus_tag="VVR63_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HEU6128466.1"
                     /translation="MNKKILETLEFDKVKALFEPHLLTEQGLEQLRQLAPTAKADKIK
                     QAFAEMKEMQALFVEQPHFTILSTKEIAGVCKRLEMRADLNIEEFLLLKRVLLASREL
                     QNFYANLENVSLEELALWFEKLHDFPQLQGNLQAFNDAGFIENFASEELARIRRKIHD
                     SESQVRDVLQDLLKQKAQMLTEGIVASRNGRQVLPVKNTYRNKIAGVVHDISASGNTV
                     YIEPREVVKLSEEIASLRADERYEMLRILQEISERVRPHAAEIANDAWIIGHLDLIRA
                     KVRFIQERQAVVPQLSENQEIQLLHVCHPLVKNAVANDVYFGQDLTAIVITGPNTGGK
                     TIMLKTLGLTQVMAQSGLPILADKGSRVGIFEEIFADIGDEQSIEQSLSTFSSHMTNI
                     VDILGKVNQHSLLLLDELGAGTDPQEGAALAMAILEDLRLRQIKTMATTHYPELKAYG
                     IETAFVQNASMEFDTATLRPTYRFMQGVPGRSNAFEIAKRLGLSEVIVGDASQQIDQD
                     NDVNRIIEQLEEQTLESRKRLDNIREVEQENLKMNRALKKLYNELNREKETELNKARE
                     QAAEIVDMALSESDQILKNLHSKSQLKPHEIIEAKAKLKKLAPEKVDLSKNKVLQKAK
                     KKRAPKVGDDIVVLSYGQRGTLTSQLKDGRWEAQVGLIKMTLEEKEFDLVQAQQEKPV
                     KKKQVNVVKRTSGRGPQARLDLRGKRYEEAMNELDTFIDQALLNNMAQVDIIHGIGTG
                     VIREGVTKYLQRNKHVKSFGYAPQNAGGSGATIVTFKG"
     gene            complement(43175..43723)
                     /locus_tag="VVR63_000412"
     CDS             complement(43175..43723)
                     /locus_tag="VVR63_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HEU6128467.1"
                     /translation="MISFLLLLVLVWGFYIGYRRGLLLQVYYLISAMASAFMAGQFYK
                     GLGEQFHLLLPYANSQEGQGTFFFPSDQLFQLDKVFYAGIGYLLVFGIVYSIGRLLGL
                     LLHLIPSKKLGGKLFQVSAGILSMLVTLFVLQMALTILATIPMAVIQNPLEKSIVAKH
                     IIQSIPITTSWLKQIWVTNLIG"
     gene            complement(43720..44022)
                     /gene="zapA"
                     /locus_tag="VVR63_000413"
     CDS             complement(43720..44022)
                     /gene="zapA"
                     /locus_tag="VVR63_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HEU6128468.1"
                     /translation="MANLNRFKFTFGKKSLTLTSEHDNLFMEEIAKVATEKYQAIKEQ
                     MPSADDETIALLLAVNCLSTQLSREIEFDDKEQELEELRHKLVTCKQEQSKIEDSL"
     gene            44109..44981
                     /locus_tag="VVR63_000414"
     CDS             44109..44981
                     /locus_tag="VVR63_000414"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HEU6128469.1"
                     /translation="MASITLTPSEKDIQAFLEHYQTSLAPSKNPYIRYFLKLPQATVS
                     IYTSGKILLQGEGAEKYASFFGYQAVEQTSGQNLPLIGTDEVGNGSYFGGLAVVAAFV
                     TPDQHDFLRKLGVGDSKTLTDQKIRQIAPILKEKIQHQALLLSPSKYNEVIGDRYNAV
                     SVKVALHNQAIYLLLQKGVQPEKIVIDAFTSAKNYDKYLAQETNRFSNPISLEEKAEG
                     KYLAVAVSSVIARDLFLENLENLGRELGYQLPSGAGTASDKVASQILQAYGMQGLNFC
                     AKLHFKNTEKAKNA"
     gene            44993..45607
                     /gene="lepB"
                     /locus_tag="VVR63_000415"
     CDS             44993..45607
                     /gene="lepB"
                     /locus_tag="VVR63_000415"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEU6128470.1"
                     /translation="MNLFKNFLKEWGLFLLILSLLALSRIFFWSNVRVEGHSMDPTLA
                     DGEILFVVKHLPIDRFDIVVAHEEDGNKDIVKRVIGMPGDTIRYENDKLYINDKETDE
                     PYLADYIKRFKDDKLQSTYSGKGFEGNKGTFFRSIAQKAQAFTVDVNYNTNFSFTVPE
                     GEYLLLGDDRLVSSDSRHVGTFKAKDITGEAKFRFWPITRIGTF"
     gene            45886..48252
                     /locus_tag="VVR63_000416"
     CDS             45886..48252
                     /locus_tag="VVR63_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HEU6128471.1"
                     /translation="MEVYFSGTIERIIFENPSNFYRILLLEIDDTDAEDFDDFEIIVT
                     GTMADVIEGEDYTFWGQIVQHSKYGEQLQISRYDRAKPTSKGLVKYFSSSHFKGIGLK
                     TAQKIVDTYGENTIDEILQHPEKLEGIAGLSAKNREAFVSTLRLNYGTEMVLSKLANY
                     GIPNKLAFQIQDFYKEETLDVVENYPYQLVEDIKGLGFTIADQLAEELGIESQAPERF
                     RAGLVHSLFQACMETGDTYVEARDLLEQTLTLLESSRPVELDPSQVAQELSYLIEEDK
                     VQQIDTKIFDNSLFFAEEGIRSHLVRILEKGEQKSHHLETIQKHITTIEQELGIEYDN
                     IQKQAICDAIQNKVFILTGGPGTGKTTVINGIIAVYALLEGLDLRKKSNLPILLAAPT
                     GRAARRMNELTGLPSATIHRHLGMTGDDDTSHLEDYLDADFIIVDEFSMVDTWLSNQL
                     FSNISSNSKILIVGDSDQLPSVSPGQVLADLLHIPLIPQTRLEKIYRQSKESTIVTLA
                     SQIRQGILPADFTQKKADRSYFEIASGHIPATIEKILGAALRNGIPARDIQVLAPMYR
                     GTAGIDAINQLMQDLLNPPQKDQLSFEAPQCHYRKGDKVIHLVNDAEINVFNGDLGAI
                     TDLIPGKYTESKQDEIVIDFDGNEVSYPRNEWYKIRLAYAMSIHKSQGSEFPVVILPI
                     TSASRRMLERNLIYTAITRAKSKLILLGELQAFDHAIQHIGTARKTYLIERFSDLLEN
                     VEEKQQAVSETVTSSASEQSYILTEENWNRIPAMIGITDTDLKEIFGK"
     gene            complement(48300..49583)
                     /locus_tag="VVR63_000417"
     CDS             complement(48300..49583)
                     /locus_tag="VVR63_000417"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HEU6128472.1"
                     /translation="MSVSFENKETNRGVLTFTISQDQIKPELDRVFKSVKKSLNVPGF
                     RKGHLPRPIFDKKFGEESLYQDVMNALLPNAYEAAVKEAGLEVVAQPKIDVTSMEKGQ
                     DWVIAAEVVTKPEVKLGDYKNLEVSVDVEKEVTDADVEERIERERNNLAELVIKEAAA
                     ENGDTVVIDFVGSIDGVEFDGGKGENFSLGLGSGQFIPGFEDQLVGHSAGETVDVIVT
                     FPEDYQAEDLAGKEAKFVTTIHEVKAKEVPALDDELAKDIDEEVETLADLKEKYRKEL
                     AAAKEEAYKDAVEGAAIDTAVENAEIVELPEEMIHEEVHRSVNEFLGNLQRQGINPDM
                     YFQITGTTQEDLHNQYQAEAESRTKTNLVIEAVAKAEGFDASEEEIQKEVEQLAADYN
                     MEVAQVQSLLSADMLKHDITIKKAVELITSTATVK"
     gene            complement(50389..51525)
                     /locus_tag="VVR63_000418"
     CDS             complement(50389..51525)
                     /locus_tag="VVR63_000418"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HEU6128473.1"
                     /translation="MKHSVHFGAGNIGRGFIGEILFKNGFHIDFVDVNNQIIHALNEK
                     GKYEIEIAQKGQSRIEVTNVAGINSKEHPEQVIEAIQKTDIITTAIGPNILPFIAELL
                     AKGIEARRVAGNTQALDVMACENMIGGSQFLYQEVKKYLSPEGLTFADNYIGFPNAAV
                     DRIVPTQSHEDSLFVMVEPFNEWVVETKRLKNPDLRLEDVHYEEDLEPFIERKLFSVN
                     SGHATSAYIGAHYGAKTILEALQNPNIKSRIESVLAEIRSLLIAKWNFDKKELENYHK
                     VIIERFENPFIVDEVSRVARTPIRKLGYNERFIRPIRELKELSLSYKNLLKTVGYAFD
                     YRDVNDEESIRLGELLAKQSVKDVVIQVTGLDDQELIERIVEYI"
     gene            complement(51587..52024)
                     /locus_tag="VVR63_000419"
     CDS             complement(51587..52024)
                     /locus_tag="VVR63_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU6128474.1"
                     /translation="MKLEKHLIKLNKQFSNKEEAICYCGQVLYEGGYVNEDYIEAMIE
                     RDKELSVYMGNFIAIPHGTDAAKKDVLKSGITVVQVPRGVDFGNVSNPQVATVLFGIA
                     GIGNEHLEIIQKISIFCADVDNVLKLADAQSKEEVLRLFDAVE"
     gene            complement(52026..53981)
                     /locus_tag="VVR63_000420"
     CDS             complement(52026..53981)
                     /locus_tag="VVR63_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEU6128475.1"
                     /translation="MLLTKREEQLLKAFLHVGKLSMQDMTEILQVSSRTIYRTLSDLT
                     DSMEQYGIEITKHGKYYILTGELDDLPTELEVLVEYSPQERQELITYRLLTESGFVTN
                     EALQECTKVSNVTIIQDISDIDKRLLDFDLKIERQKGYRISGDSVGKRRFLAILLTNC
                     ISVADFSTGNFGSFDILEADRTRLASQIVNKQLSGFPDMDARMKMFFAILLSLIGQEQ
                     NIENSPNTSKQALEISQKIFQAYSKQTAQFYSIQEIIYFASILDELIIKRQDNPLFTE
                     KFDGEFFYNISNLIDTVSMYTKIDFFKDKVLFNFLFHHIRLSLGVPILFQGENLPESV
                     QILVERNKFLYTVISLLVNDIFPKYLHTEYEYGMIALHFISSLGRSPEIYPVRVLLLT
                     DERRVTRDLLVSKIKSVAPFVELIDIQSLVDYHSIDLSQYDYILSTKPLTNQEIDVIS
                     SFPTVKELLELQERLQYVQAHRTIVARDAIAPEKSYDLQDYLISSSQLLSQFELVQLE
                     NNQSFEHTVEQIIQYQKNVSDRDYLTRKLLSHFQNSPMAIPNTGLVLLHSQSSKVTTN
                     SFTMFELKLPISALSMKREKEEVKRCLLMLMSKEASEEARDLMTAISQSIIENHLYTE
                     IYKTGNQSIIYQMLNTIFNEKIKKLEN"
     gene            complement(54005..55774)
                     /locus_tag="VVR63_000421"
     CDS             complement(54005..55774)
                     /locus_tag="VVR63_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HEU6128476.1"
                     /translation="MEEKVSLKVRVQKLGTSLSNMVMPNIGAFIAWGVLTALFIADGY
                     LPNEQLATVVGPMLTYLLPILIGYTGGYMIHGQRGAVVGSIATVGAITGSSVPMFIGA
                     MVMGPLGGWTIKKFDEKFQEKIRPGFEMLVNNFSAGLVGFALLLLAFYAIGPVVSTLT
                     GAVGNGVEAIVNARLLPMANIIIEPAKVLFLNNALNHGIFTPLGVEQVAQAGKSILFL
                     LEANPGPGLGILLAYAVFGKGSAKSSSWGAMVIHFFGGIHEIYFPYVMMKPTLFLAAM
                     AGGISGTFTFQLLDAGLKSPASPGSIIAIMATAPKGVWPHLNVLLGVLVAAVVSFLVA
                     ALILHADKSTEDSLEAAQAATQAAKAQSKGQLVSTSVDAVVSTDSVEKIIFACDAGMG
                     SSAMGASILRDKVKKAGLEIPVSNQAISNLLDTPKTLIVTQEELTPRAKDKSPSAIHV
                     SVDNFLASPRYDEIVASLTGASPIAEIEGDIPTSAPVDSQEIDLNHIDAVVVAYGKAQ
                     GTATMGCETIRAIFRNKNIRIPVSTAKISELGEFNSKNIMIVTTISLQAEVQQAAPNS
                     QFLIVDSLVTTPEYDKMAARMYK"
     gene            55983..56724
                     /locus_tag="VVR63_000422"
                     /pseudo
     CDS             55983..56724
                     /locus_tag="VVR63_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT        16883 a        12743 c        10587 g        16511 t
ORIGIN      
        1 gaacaatttc aacacgataa tcggcaagta gacctaaaaa tactggctag acatattcat
       61 cgtctcaaga aaaaacagtc tgattggaaa gtacaataca ctcgttgtct tgatatcatc
      121 tttcctgagt tggataaaat cgttggaaag cattcagaat atacctacca actcttgacg
      181 cgctacccta atcctcagaa aaggattgag gcaggatttg ataagctgat agaaattaag
      241 cgattgaccg cttctaaaat tcaggatatc ctctcagtcg cacctcgttc tatcgaaaca
      301 acatctcctg ctcgtgaatt cgaaatcatc gaaatcatca aacattacaa gaggctcatt
      361 gacaaggcgg aaacatgtgt caatgacttg atagctgagt tcaactcagt catcacgacg
      421 gttactggga ttgggggtcg tttaggggcg gtcattttag ccgagattcg aaatattcat
      481 gcctttgata atcctgctca attacaagct ttcgctggac tggattcttc tatttatcag
      541 tcaggtcaga ttgatttagc tggaagaatg atcaaacggg gttcccctca tctgcggtgg
      601 gcactcatac aagctgccaa agcatgcgct cgcttttcac ctgcttttaa ggcctatctt
      661 aagactaagt tagaacaagg aaaacattac aatgtagcca tcatccacct tgcaaaaaaa
      721 cttatccgaa ccctgtttta tatcctaaaa aagagctgcc atttgacgaa caaaaagtga
      781 tgtaatttct gaaattaaca caggattacc tttgaaaaaa tggacttttt caagggcttt
      841 ttgccgtgct ctaaaatcat cgccaaatca tcaaattgaa ataagaaata gtttagataa
      901 aactattgac ttttcttata gtttgtcttt cttctatctt ccattatatc atactttttc
      961 agtctatggt agctctcttt aaaaggctcc gatactgccg ccacctccgc ctccagagaa
     1021 gccaccgcca gaacttccac ttccagaaga tacggagtag gtacttgctg tatttgcgac
     1081 actagcataa tggctcattt gcgcgcttga atgataaaac atactgtgcc agccataagc
     1141 tacatagaga ttgatatctg gattttcaac ttgaatctga tgaaccttca tcaaatgact
     1201 aaccttgtcc gcatagccaa ataaggttgc atagaccaag agacgattcc aaacaacaat
     1261 actttccaat tcagccttat ccagtcgtgc aatctcacgt aacatatttt caaaactggt
     1321 ccagagatag tagacctcag ctcccgcttc atttagaaca ccatcacgat tatctagtcg
     1381 aagcttccaa taatagaaaa cagacaaaac taaccctaga aaaccaagta ttggcaaagg
     1441 gaggtaaaga tagccatgaa cgtctaaact gtacaagaac aaaccaaatc cgataaatag
     1501 gggcaagata gtcaagacac ccatacccac ttgcaaagtc ttttccaaac cagttaaagg
     1561 acgatagtaa tctgggagcc cccagaagga aactcgtttt ctcactcctt cttgcatctg
     1621 gttcaatacc tcttcaaaag aagatttgag ttgaagccct cttgcttgaa tccgtttttc
     1681 atcagaaact ttggctctac gataaagact atcagatacc ttgtaatccg caaacaaatt
     1741 ggaaagagtt tcttcttttt tacctgaaaa ggctagattt agacagtctc tctcaaagct
     1801 tgacaaacca tcttctttta ctagcctcaa accaactgca tctccttctg aaatgataga
     1861 gacattccca cggtctatca catctagcaa ggtagcttga ataagttgat caaaggtgaa
     1921 ttttccagct cccttgacca agggactcac ttcctccaag gaggtcgagt agactgcttc
     1981 tgataaaacc ataggctcta attccattgg tggttcatag agacgatgat ttttggcata
     2041 tttgactgaa ggagtggtct ttcttctata aataaaatag aagcagacac tcaataacaa
     2101 ggagatggaa aggatcgaag ggaggaccca agtaagtagt tgtttacttt gctctttttc
     2161 tctaacaatc gagtcttcta tcttattaaa ctcttctaat cgattccctt tcaatccctg
     2221 atccctagcg ctagcaaaat cggtccgagg ccaataggca tgcaactcaa ctccacgctt
     2281 agccggaaga ttgtctaaac ggatagtata atcaaggtta ctcttttcaa tcgttccctc
     2341 tctaaaaagt ttccctgtat ggaaaaagag tttttcagcc cccttgtctc cccttacatg
     2401 aaattcaaac ttttcaatag actctgaact atctgtcaga ggttgccaat ttaattcagc
     2461 gatatcatca taaaggaaaa gtaaattttt taagttccag acgaggtcaa cttcaactat
     2521 gtcgccctcc tgacctggat tatagactct cacagtataa ccatccgctt cttctgttac
     2581 ttcgctagtc acatctgcta gttctgcacc gtttttcgca gcctgaacct ttggatgagg
     2641 gtcaatgtca aacccgctag gcatcttacc agcacgtcca agtcccacga tttggccctt
     2701 aaagtcctcc tcaaactggt aaactatctt ctgtctaaac tctgccgtat tatctgcatg
     2761 aatatacaaa tccccttgat aagagtttat cttgaaatca atggcaaaaa cagagagtgg
     2821 aagaaggcaa aacaagccta acaccagtaa gaaaaaagtt tttttcatca actaagcccc
     2881 ctttttatct ttcttatcat tatagcatct tttcgtaagt aaaggcttac ttatgttgaa
     2941 aaattacgca tttttcgata aaataggaga cagttatttt ttaatagatc agaataggag
     3001 aaatcatgag aaaaatatac ctatctattt tcacaagtct cttgctgatg ctaggacttg
     3061 tcaatgttgc tcaagccgat gaatatttac gcatcgggat ggaagcagca tatgctccct
     3121 ttaactggac ccaggatgat gatagcaacg gagctgtcaa aatcgatggg accaatcagt
     3181 atgccaacgg atacgatgtt caaatcgcca agaaaatcgc taaggactta ggtaaagaac
     3241 ctttggttgt taaaaccaag tgggaaggtc tagtccctgc ccttacttct ggtaagattg
     3301 acatgattat cgcaggtatg agtccaactg cagaacgcaa acaagaaatt gccttttcga
     3361 gcagttacta cactagcgaa ccagttttgc ttgtcaaaaa agattctgcc tacgcaagtg
     3421 ctaaatcttt ggatgacttt aatggtgcga aaatcacttc tcaacaaggt gtctacctct
     3481 acgacttgat tgcacaaatc ccaggtgcta aaaaagaaac agccatggga gacttcgctc
     3541 aaatgcgcca agctcttgag gctggtgtca ttgatgctta tgtttctgaa cgtccagaag
     3601 cactgactgc tgaagctgcg aactctaagt tcaagatgat tcaagtagaa cctggtttca
     3661 aaactgggga agaagataca gctatcgcta tcgggcttcg taaaaatgac aatcgtatta
     3721 gccaaatcaa tgccagcatt gaaaccattt caaaagatga ccaagttgcc ttgatggatc
     3781 gtatgatcaa ggaacaacct gccgaagcta caacaactga agagactagc agtagtttct
     3841 ttagccaagt cgctaaaatt ctttctgaaa actggcaaca actcttgcgt ggtgctggta
     3901 tcactctttt aatctctatc gtcggaacca tcataggtct cattattgga cttgccattg
     3961 gtgtcttccg tactgctcct ctctctgaaa acaaagccat ttatggcctt caaaaactag
     4021 tcggctgggt tctcaatgtc tacattgaaa ttttccgtgg tacgccaatg attgttcaat
     4081 cgatggttat ctactatgga actgcccaag ctttcgggat caaccttgac cgtacactgg
     4141 ctgctatctt catcgtttca atcaataccg gtgcctacat gactgaaatc gtccgtggtg
     4201 gtatcctagc agttgacaag ggacaatttg aagctgcgac tgctcttggt atgacccata
     4261 accagaccat gcgtaagatt gtcctacctc aggtagtccg taacatccta cctgcaactg
     4321 gtaatgaatt tgtcatcaat atcaaagata catctgtatt gaacgttatc tctgttgtcg
     4381 aactttattt ctcaggaaat accgtggcaa cacaaaccta tcaatacttc cagacattta
     4441 caatcatcgc cgtgatttac tttgtcctca ccttcaccgt aacacgtatc ctacgattta
     4501 tcgagcgccg aatggacatg gatacctata ctacaggtgc taaccaaatg caaacggagg
     4561 atttgaaata atgacacaag caatccttga aattaaacac ctcaaaaaat cctatggaca
     4621 aaacgaagtg ctaaaagaca tttcactcac tgtccacaag ggagaggtca tctctatcat
     4681 cggaagctct ggaagcggaa aatcgacctt cctacgctcc attaacctac ttgaaacacc
     4741 aactgatgga caaatccttt atcatggaca aaacgtcctc gaaaaaggct atgacctcac
     4801 gcaataccgt gaaaagttgg ggatggtttt ccaatccttt aacctctttg aaaatctcaa
     4861 tgttcttgaa aacacaatcg tcgctcagac aactgtccta aaacgcgaac gcacagaagc
     4921 tgaaaagatt gccaaagaaa acctggaaaa ggtcggcatg ggagaacgct actggcaagc
     4981 caaaccaaaa caactctcag gtggtcaaaa acaacgtgtg gccatcgctc gtgccctctc
     5041 catgaatccg gacgctattc tctttgatga accaacatca gctctcgatc cagaaatggt
     5101 tggagaagtc ctcaaaatca tgcaggacct ggctcaggaa ggcttgacca tgattgtcgt
     5161 aacccatgaa atggaatttg cccgtgatgt ctctcaccgt gttatcttta tggataaggg
     5221 cgtgatcgct gaagaaggta aaccagaaga cctcttcacc aatcctaaag aagaccgaac
     5281 aaaagagttc cttcaacgct atctcaaata aaaagaaaag gctgcatcaa ccgtgcagtc
     5341 tttttgctgt cctcaaaatg aaaaggcaga ttctctatct ctactacttg aaggtcaaga
     5401 atccgccgtt atccaaagat taatcttcaa atttttcata atttttttca tagaaatcaa
     5461 ttaagcctag ggctgtttca aatgaaatat tttttacttt tgcacgaccc tgcgccagag
     5521 caatgataga catttcacgc gcattcgttt ctttagagat acggtagcct gtgattttct
     5581 tatcacgaac ccagccaaca actgattcta ctttttcaaa gtttgactta gccatgtttt
     5641 tctcctattt tcttctttat aatatttaat tgtatacgtt tttactactt ttgtcaataa
     5701 aaaaaacata tattcaacga aaataattag ttcagaattt tcttacttcc tttttaaatc
     5761 cgataatata taggttttgc tagcctctac accataaata tttgctaata aaactactgt
     5821 attattaccc tcttaaggtg cgaaattatt caagttctta aaaaatgctt ctctatttcc
     5881 gtaagatagc ttatttcttc gatttaagaa ctgaagatga tagttctaac ctttagaaat
     5941 ccaagccttc actagctcaa aaactcctat ctttcttcct caataaatca tctgagagat
     6001 aggtatttct tatatccttc aaattcatca ctcctttgga tattgaggtg ctagcctaga
     6061 agcagacacc cgattatcta aaccatcctt aatagagatg acaagacaga taagctcagt
     6121 taattactta tatatctttt taatatggta tatttgtcaa caaaaagaaa tcaaatcata
     6181 ccttatactc aatgaaaatc aaagagcaaa ctaggaagct agccgcaagt tgctcaaaac
     6241 actgttttga ggttgcagat agagctaacg tggtttgaag agattttcga agagtattaa
     6301 agacagtgtg actatgcttg tcaatagata ggaaatcaaa atgaaggatg gaaatctgag
     6361 ccaaacatca taagtgctat aatgaacaga agtaagaatt gcacgataag ttttctaaaa
     6421 ccataggaat cgtccccttt cttcatcttc attatagcat atatacatca gttgtacaaa
     6481 taatatgata tttttttatt agtcctcaga caagcatatt ataaagcgtt tcattaccat
     6541 ttaagttaat ataagctgga tcaaaacctt ccattctacg aatcaaacct gcataatcat
     6601 gcttatctgc taaagcgatc ccaatcaata ctgggcctgt tcccttgcta gctcgtttga
     6661 tatactcaaa acgtgtgata tcatcatttg gccccaggat atcatttaca aactcacgca
     6721 aagctcctgg acgttgtggg aaattgacca caaaataatg tttgatacca tcataaatca
     6781 aggcacgctc ttccatttct ggcatacggt tgatatcatt atttcctcca gaaatgatac
     6841 aacaaatggt tttcccctta atatattcag ctaaaacctc taaagaggcg atactagctg
     6901 ctccagcagg ttctgcgact atcccttgct tagagtaaag gtcaatcaag gtttcagaaa
     6961 tcaatccctc atcgacacct accaaagttt gaatatgttg acgagttgct tcataggtca
     7021 actgacctac cttttgcaca gcaatcccat ccgcaaattt atcaatttcc ttgagtttga
     7081 ctggacctcc agcctcaaag gcagctttca tggaacgcgc tccattcgcc tctactccga
     7141 taacctcaat ctctggactt gtttccttga tataggtaga aaccccggca atgagaccgc
     7201 caccaccaac aggaaccaag acagcatcaa aatcaatcga ttcttttcga gcttcttcta
     7261 aaatctcata agcaactgtt ccttgacctg cttgaacatg agcatcatca aaaggatcaa
     7321 taaaggtacg attttcagag actgtaaatt cttgagctgc tttggctgag gcatcaaagg
     7381 tatctccaac tagtttaata gttacaaaat ccccaccaaa aaagcgaacc tgaccaatct
     7441 tttgttgtgg cgtagtaatg ggcataaaga tagtagcagg aattttcatt tcattacaag
     7501 tataggctac tccctgcgca tgatttcccg cagaagcgca aactacccca cgttcacgtt
     7561 cttccttgct gagctgggaa atggcataat aggcaccacg aattttaaag gagcgaacac
     7621 gctgggcatt ttcttttttc aaataaatct tagcaccata cttctccgat aaataatgat
     7681 cgtaatccag tggagtattc acaaccacac cgttcaagac cttgtgagcc ttgattatat
     7741 cttttgaact taacatataa aacctctttt tctataaaaa acagtcacta atgactgttt
     7801 tttagttatt catctccgaa aatttcagta acactttcat ggtatttatg agccatacga
     7861 atcgaaaact ctttaggaag ttcataacga tttgtggaaa tccaatcata taaccattct
     7921 accaaacttt cttcactatc attacgatgg aagataaaat agtttaaaat ttctttatat
     7981 tctacatcat tcaaatccaa cgtgtctaca aattgactac gaggaacaaa attagaatct
     8041 aattttctta gttgatctgt caattctccc aattgtaaat ccaactgaaa aaatagtttt
     8101 tgcagttgcc tatcagtttc atcacatcct gtcttgatag aaaacaaatt ggtaatattc
     8161 atatgatttc aacccctaaa taagtacatc taatatccca cgaatagctg aagctaaagt
     8221 tttcgcagtc cagtcattta aacccgattc tttcaatcca gatgcaataa tttgctctat
     8281 ttgatataaa ccgccatcta tcgtctcatt tattctgcga agaggacctt caatatagga
     8341 taaagcttct ccgaatctaa cagctgattt aggtcctaat gatttaccaa ctatatttgt
     8401 taatattttt tatttctcaa aatccatttc gctatataac gagcagattt agtcgcacca
     8461 gctctctcaa acggagaatg aatttcaaga ccttcttctc tagctatttg tgccaatttg
     8521 aagaattgtt caaaggtcat atgcaaccta ccatcttcaa aattagcatc atcataaatg
     8581 ttaattacag cattttcatc atacgaccaa tctgctttat tttggtctgc tagcactatt
     8641 accgacggtg taattacatt atacaactag aaccaataat aacgatgcaa tttttctcat
     8701 aatctttttc ataaaatcat ctccagcgct atatatttct aattagttat agattttgaa
     8761 tgcatcatcg tcgtttttac caacgaatgg cattgcttta cgcaattctg caccaacttt
     8821 ttcaatttca aggttagctg cttgttcacg gtaagcagtc aattttggac gtccagcttt
     8881 atagtcattt acaaagtcat ttgcaaattt accattttgg atgtctgcca agacagcctt
     8941 catattttct ttaacttgtt cagtgattac acgtggacct gatacatagt caccgtattc
     9001 agcagtgttt gaaatagatt gacgcatttt cttgaatcca ccttcgtaga tcaagtcaac
     9061 gatcaatttc atttcgtgaa gaacttcaaa gtaagccaat tctggagcgt aacctgcttc
     9121 tgtcaagact tcgaaacctg cttcgataag ggcagtcaaa ccaccacaaa gtacagcttg
     9181 ttcaccaaac aaatcttctt cagtttcttc tttgtaagtt gtttcaagaa gacctacacg
     9241 agccgctcca acacctttac accagtccat agcaatgttt ttagcatttc ctgttgcatc
     9301 ttggtatact gcataaagag ctggaacacc aaatccttct tcgtaagtac gacgtaccaa
     9361 gtgtcctggt cctttaggag cacacatgaa gacatctaca tccgcaggaa ctttgataaa
     9421 ttcaaagtgg atgttgaaac catgggcaaa tccaactgcg tttccagctt ccaagtttgg
     9481 agcgatttct gcttcgtaca attcttgttg aatttcgtct ggcgccaaga tcatgataac
     9541 atcagccaac ttagtagctt ctgctactgt gtaagtatca aatccatctt cttttgcttt
     9601 atcaaaagat ttacctggac gtacaccgat aataacgtca cgacctgaat cacgcaagtt
     9661 ttgagcatgc gcatgccctt gtgaaccata accgataacg gcgatttttt taccgtcaag
     9721 tgctgctact ttaacatctt tttcatattc catttgaact gtcatagctt ttctctcttt
     9781 tctattattt attgcctttt aagctggttt aacaaattta agttggattt ttaatcgcgg
     9841 gtaaatccag ttgcacccgt tcgagcaata ttgcgaatac cgtatgggcg aatgactcgc
     9901 aatagggctt cgctcttttc tgcatttccc gtcatctgaa tggtaatcga gcttggcgct
     9961 acgtctacca ctgttgcacg gaaaggttga ataatcgcta aaatctcagc tctcttctca
    10021 gctggcgctg acatcttaac caaaatcacc tcgcgctcca aatgaggctt gtctgtaata
    10081 tctcgaatgc gaatcacatc aatctgacga ttgagctgtt tgatgatttg ctccacttca
    10141 tcatgagaag caacatcaat aataatagtg atacgcgata cattcggatc ttctgttgct
    10201 ccaacagaga tgctttcaat attaacctga cgacgagata ggacacctgt aaagcgattg
    10261 aggactcctg aacgattttg tagttttgct gttaacattc tacgcatgga actgcacccc
    10321 caacatctca tgattactct taccagccgg taccattggt aacacctgtt ccttacgaga
    10381 aatatctacc tcaattagca taggaacatc ctcagtgatg acttcaaggt cttgagccaa
    10441 ggtctcagga ttgtcaaact tatagttttt aataccataa gcctgcgcca tcaattggaa
    10501 atcaggaagg gtatcaaaga ccgactctga tgttctgcct tcatagaagg attcctgcca
    10561 ctggcgaacc attccgagtg aatgattgtt cagcataacc accttgattg gcaccttgta
    10621 aatattcaaa atagccaact cctggttggt catttggaaa ccaccatccc caacaaacaa
    10681 gactacttcc ttatctgggt tagcaatttt agcaccgatt gctgctggaa ttccaaagcc
    10741 cattgttccc aaaccacctg aagtcactaa ctgacgttca ttttggtagg gataatactg
    10801 agctgtccac atttggtgtt gaccaacgtc tgttaccaca atggcatctc cattcgtcaa
    10861 ttcaccaatt cgttcaataa ctgcttgcgg ttgaaccaca cgctctttct tgtcatacga
    10921 acgaacacga ttcttgtctt tagtgacttt ctcaatccac ttttcagtat tgttgtgaac
    10981 tgttggttct gctagcaaca tttgcaaggc cttcttagca tctccaacta caggaatgtc
    11041 tgcactgata atcttgccaa tctcagctgg gtcaatatca atgtgggcaa ccttagcatt
    11101 cttagcgaaa gtcttaggat tccccgtcaa acggtcatcg aaacgagaac caatactaat
    11161 cataaagtcc gcttccgtca tggcaatatt tgctgcgaat gacccgtgca tgcctcccat
    11221 tccaagaaag agtgggtgac tcgttgcaat cgttccttgt cccaaaagac tggttaccac
    11281 tggaatttga tagcgttctg caaattcatt tagttccgta gcagcctcag cataactaat
    11341 tccaccacca gctaacaaga ctggcttttt agccttggac aattgcttca agattttctt
    11401 gatttgcata tcattcggct caagagtcgg ctgataactt ggtaaattca cttctggtga
    11461 ataaatgaag tctgtttcta aagcagatat gtcttttggt aggtcaatta caactggccc
    11521 tggacggcct gtagttgcga tatggacagc ttccgtaatg atacgcggaa tatcagctgt
    11581 ctcacgaact tggtaattgt acttagtgat tggcatggta attcctacga tgtctgcctc
    11641 ctgaaaggca tccttcccaa tccctgctcg cgccacctga cctgtaaaga ccaaaagggg
    11701 aacgctatcg ctcatagcat ccgcaatccc tgtaatggca tttgttgctc ctggtccact
    11761 agtgacgacg gcaacaccca actttccagt tgatttggca tagccttcag cttcatgcaa
    11821 acaaccttgc tcatggcgcc ctagaatgtg gcgaatgcct ttaaaattat atatcgcatc
    11881 ataaaaaggc aaaaccgcac caccaggata accaaagatg gtatcaactc ctaaatcacg
    11941 aagtgtttcc aaaactaggt ccgaccccgt cttaggagat tctaaactga ttttctccat
    12001 tattcccctt tctttcctct taaaaataac ttgttactat cataccattt tttcaaaatt
    12061 tttcaagata aaagaagaaa ttttctgaat tttctatttt aacgtttatt tatgaatgtt
    12121 atttttgttt ttattaaaaa gataccgatt tcatttacta aaaagaaaaa agaactgatt
    12181 tctcagtcct tcattaatct tattccacac taaataggta tgggtaaaca ggttgttgac
    12241 cttggtgaat ctcgacttca acgtcttcga attcttctac gatttcttga gcgatttcat
    12301 tggcaagttc ttcgcttccg tcttcaccga catagaaggt tacgatttca ctgtcttcat
    12361 ccaacatatg tttcaaggtt tcagtcaatg tttggtgcat atcagggttt gacacaagaa
    12421 tttttccatc caccatacct aaattatcgt tttcatggat ttctaagcca tcgatcgttg
    12481 tatcacgcac ggctgttgtg acgcttccgc taacgacatc gctaagagca gctgtcatac
    12541 gctcttggtt ttcttcaatg gacttgcttg gatcaaaggc aagaagactt gtcatacctt
    12601 gaggaagagt gcgagcctct accactaccg ctggttgctc caaaacttct gccgcagatt
    12661 gagctgccat gaagatgttc ttgttgtttg gcaagaagat gatgttacgg gcattaacct
    12721 gttcaacagc cttgataaag tcttctgttg aagggttcat ggtttgaccg ccttcgataa
    12781 cataatccac gccttgagaa cagaagatat ctgctagacc tttaccagcc accacagcaa
    12841 tcaaagcata ctctttttct tcagccgact tgataacttg agtagcttct ttctcaacct
    12901 gtgcttcgtg ttggttacgc atattgtcaa cttttacctt gaccaagcta ccatatttga
    12961 gaccttcttg cataacaagt cctggatctt ctgtatgaac atggactttg acaatttcat
    13021 catcgttaac aacgaggaga gaatctccaa gctcatccaa gtagttacgg aattcatcgt
    13081 agtcaaaatc tttagcatag gttggacctt gcttaagagc taccatgatt tcagtacagt
    13141 aaccaaacgt gatgtcctca gtcgctacgt gaccagctac agacttatga tgctctacat
    13201 tgatcatctc actcatgttg gcaggagtcg ctacaaagtc ctcagatgca atatattcgc
    13261 cagtaagggc tgaaaggaaa ccttcgtaga tgaagaccaa tccttgacca cctgagtcca
    13321 caacgccaac ttctttcaat actggaagca tgtctggtgt tttagctaga gctgttttag
    13381 caccttccaa ggctgcgcgc atgacttcaa cagtgtcatc tgtttgctca gcttttttct
    13441 tagcaccgat agcagctcca cgagaaactg tcaaaatcgt tccttcaaca ggtttcatca
    13501 ctgccttata ggcaacttcc acacctgatt ggaaggccag agccaagtct tgacctgtta
    13561 actcgtcttt atccttgata gcttgggaaa atccacggaa aagctgagac gtaatcactc
    13621 ctgagttccc acgcgcaccc atcaaaagcc ctttggcaag aatgctcgct acttctccaa
    13681 ctgtagaagc tggcttgtct gcaacttctt tagcaccatt ttcaatggtc attcccatat
    13741 ttgtcccagt atctccatct ggaactggaa agacgtttaa tgaattgaca tattcagctt
    13801 gcttattcaa gcgagttgat gcagcctgca ccatttcttg aaataagcta gtagtaattt
    13861 ttgacacggt tattctccta caactttgat attttgaatg tagacattta cagtctgagc
    13921 agtaattcca agctggtttt ccaagctaaa ggcaacacgc tcttgaatgt tttttgacac
    13981 ttcactaatc tttgttccgt agcttaacac ggtatataca tcaactgcaa tactgccatc
    14041 ttcggctgcc tttacgacga cacctttaga ataattttcc ttacctagca gggcttggaa
    14101 attatctttg agggcatttt tactagccat accgaccaca ccaaaaatct cagttgctgc
    14161 tccacctacg acggttgcaa tcacttcatc tgttagttcg atttgaccat cttttgtatt
    14221 aatttttaca gtcatccttt ttacctcaac tagttgatac tctattttat catatttcag
    14281 cccaagtgta aaagcagaat gatgtatcag cggatattta ctctattttt caaacgatgt
    14341 tatacccaca ataaaagaaa aaagacccta aggtctcctt tgcttttatt attaaacgcg
    14401 ttcaacttta cctgatttca aagcacgagc tgaagcccaa acttttttag gtttaccatc
    14461 gataagaaca gtaacttttt gaaggtttgg ttttacggca cgttttgttt ggttcatcgc
    14521 gtgtgaacgg ttgtttcctg atacagtctt acgacctgta aagtaacata ctttagccat
    14581 tgtgttttcc tcctattaga tctaatatag cggatgtgct agcaccacat accgtactat
    14641 gttatcacac tttcttgttt tttgcaaggg aattggaaga ttttttattt gtgtcttaaa
    14701 tcaggtcttg cgtgacattt tctgctctcc acatgccatt gttgattaac agaacaccag
    14761 aattaaaatt atgtgtataa aaatcatctc taactgcagc taagggtata gccgtcaagt
    14821 ccaaatccca cagctcatct atcgattttc ttacaacaat atctgaatcc aaatacagta
    14881 cacgagactc gcttacatac tttggaataa aatacctaaa aaaagccgca tatgaaagtc
    14941 cctcaaaggg gagacgataa cctttcagaa tactactgtc aatctgaaca ttcacaatct
    15001 cactattcaa agtctctagt cttttttcca tcaattggaa ccattctcgc ggaaggtcat
    15061 cattaaaaac ataaaactta agattataat gatgaacaca aagagatttt attgttgttt
    15121 caactttatc catataagca ttatctgcac ctaagacaat cgcttttttc tcttctttca
    15181 ctctttatct tatttctttt tattcccatc atattattcc catcatatgt ttctacgtaa
    15241 ccattatttt cgcctattcg ttcgtaaaac cataccagtg gagattttag atgaagtccc
    15301 attacggttt acaattttta cattacgaca cggagtttta caaatcgatt tcatttgcca
    15361 aacgtagtta gtgaggcagt tagctagttc gccaaatagc gactagcgtc caacaatttg
    15421 gaactttagc tccaattgtt ggtactgagt cacatcttct cctctaactc tacgtctgga
    15481 tacttgtccg caaaccagcg gagggcaaag tcattttcaa agagaaagac tggttggtca
    15541 aaacggtctt tggctaagat attgcgactt gacgacatcc gttcatccaa gtcctcaggc
    15601 ttgatccaac gaacggtctt tttacccatt gggctcatga ccacttccgc attgtattcg
    15661 ccttccatac ggtgtttaaa gacttcaaac tggagttgac caacagctcc cagcatgtac
    15721 tcacctgttt ggtaattctt ataaagctga acggctcctt cttgcaccaa ttgctcaatc
    15781 cccttgtgga aggatttttg cttcataaca ttcttggcag aaactttcat gaaaatttca
    15841 ggagtaaagg ttggcagtgg ttcaaattca aacttgtttt ttccaaccgt caaggtatcc
    15901 ccaacctgat aagtaccggt atcgtaaacc ccgataatat cacctgccac ggcattgatc
    15961 acattctcac gactttccgc cataaactgg gtaacattag atagtttagc ccccttacca
    16021 gtacgaggga gattgacact catgccgcgc tcaaattcgc ctgatacgat acggacaaag
    16081 gcaatacggt cacggtgacg aggatccatg ttggcttgga ttttaaagac aaagcctgag
    16141 aaatccttgt cataaggatc cacaatttca ccgtctgttt tcttgtgacc atgtggttct
    16201 ggagcaaact tgaggaagat ttcaaggaag gtctgcacac caaagtttgt cagggctgaa
    16261 ccgaaaaaga caggcgtcaa ttctccagcc agaatagctt cctctgaaaa ctcattccca
    16321 gcttcattta aaagctcaat gtcatccttg acttgctcgt agaaaggatt gctaccaaag
    16381 agtttgtccc cgtcttctag actggcaaaa cgctcatccc ctttgtaaag ctctaaacgt
    16441 tggttataga ggtcatacaa gccctcaaag gctttcccca tcccgatagg ccagttcata
    16501 gggtagctag caatgcccaa gatttcttcc aattcttgca agagatccaa aggctcacga
    16561 ccgtcacggt ccagcttgtt cataaaggta aaaactggaa tgccacgatg tttcacaacc
    16621 tcaaacaatt tcttggtttg agcctcgatc cccttggcag agtccacgac catgaccgca
    16681 gcatccaccg ccatcaaggt acgataggta tcttctgaga agtcctcgtg ccctggcgtg
    16741 tctaagatat tcacgcgctt gccgtcgtag tcaaattgca taacagatga agtaacagaa
    16801 atcccacgtt gcttctcgat atccatccag tcagatttag caaaagtccc tgttttcttc
    16861 ccttttaccg taccagcctc acgaatctca cccccaaagt agagtaactg ctcagtgatg
    16921 gttgttttcc ccgcgtccgg gtgggagata atggcaaagg tacgacgttt cttaatttct
    16981 tcttgaatat tcataagttc tctttctttg attctctatt tttcttgttt caatagctga
    17041 gaatgatttt tacattggat tttaccattc ctttcaatac tccattatat cggattttag
    17101 catttttttc aatttctatc tcttttcact tccccctccc ttatttatag gaaaatatgg
    17161 taaaatagaa cagactaaaa atcatcattt cacgaaagga tgcaagatga aaattacgca
    17221 agaagaggta acacacgttg ccaatctttc aaaattaaga ttctctgaag aagaaactgc
    17281 tgcctttgcg accaccttgt ctaagattgt tgacatggtt gaattgctgg gcgaagttga
    17341 cacaactggt gtcgcaccta ctacgactat ggctgaccgc aagactgtac tccgccctga
    17401 tgtggccgaa gaaggaacag accgtgatcg cttgtttaaa aacgtacctg aacaagacaa
    17461 ctactatatc aaggtgccag ctatcctaga cgatggagga gatgcctgat gacttttaac
    17521 aataaaacta ttgaagagtt gcacaatctc cttgtctcta aggaaatttc tgcaacagaa
    17581 ttgacccaag caacacttga aaatatcaag tctcgtgagg aagccctcaa ttcatttgtc
    17641 accatcgctg aggagcaagc tcttgttcaa gctaaagcca ttgatgaagc tggaattgat
    17701 gctgacaatg tcctttcagg aattccactt gctgttaagg ataacatctc tacagacggt
    17761 attctcacaa ctgctgcctc aaaaatgctc tacaactatg agccaatctt tgatgcgaca
    17821 gctgttgcca atgcaaaaac caagggcatg attgtcgttg gaaagaccaa catggacgaa
    17881 tttgctatgg gtggttccgg tgaaacttca cactacggag caactaaaaa cgcttgggac
    17941 cacagcaagg ttcctggtgg gtcatcaagt ggttctgccg cagctgtagc ctcaggacaa
    18001 gttcgcttgt cacttggttc tgatactggt ggttccatcc gccaacctgc tgccttcaac
    18061 ggaatcgttg gtctcaaacc aacctacgga acagtttcac gtttcggtct cattgccttt
    18121 ggtagctcat tagaccagat tggacctttt gctcctactg ttaaggaaaa tgccctcttg
    18181 ctcaacgcta ttgccagcga agatgctaaa gactctactt ctgctcctgt ccgcatcgcc
    18241 gactttactt caaaaatcgg ccaagacatt aagggcatga aaattgcttt gcctaaggaa
    18301 tacctaggcg aaggaattga tccagaggtt aaggaaacaa tcttaaacgc ggccaaacac
    18361 tttgaaaaat tgggtgctat cgtcgaagaa gtcagccttc ctcactctaa atacggtgtt
    18421 gccgtttatt acatcatcgc ttcatcagaa gcttcatcaa acttgcaacg ttttgacggt
    18481 atccgttacg gctaccgcgc agaagatgcg actaatcttg atgaaatcta tgtaaacagc
    18541 cgtagccaag gttttggtga agaagtgaag cgccgtatca tgctgggtac tttcagtctt
    18601 tcatcaggtt actacgatgc ctactacaag aaggctggac aggtccgtac acttatcatt
    18661 caagatttcg aaaaagtctt cgcggattac gatttgattt tgggtccaac tgctccaagt
    18721 gttgcctatg acttggattc tctcaaccat gacccagttg ccatgtactt agccgaccta
    18781 ttgaccatac ctgtaaactt ggcaggactg cctggaattt cgattcctgc tggattctct
    18841 caaggtctac ctgtcggtct gcaattgatt ggtcccaagc actctgagga aaccatttac
    18901 caagttgctg ctgcctttga agcaacaaca ggctaccaca aacaacaacc cgtgattttt
    18961 ggaggtgaca actaatgaac tttgaaacag tcatcggact tgaagtccac gtagagctca
    19021 acaccaattc aaaaatcttc tcacctactt ctgcccactt tggaaatgac caaaatgcca
    19081 acactaacgt gattgactgg tctttcccag gagttctacc agttctcaat aaaggggttg
    19141 ttgatgccgg tatcaaggct gctcttgccc tcaacatgga catccacaaa aagatgcact
    19201 ttgaccgcaa gaactacttc tatcctgata accccaaagc ctaccaaatt tctcagtttg
    19261 atgagccaat cggttataac ggctggattg aagtcgagct agaagacggt acgaccaaga
    19321 aaatcggtat cgaacgtgcc cacctagagg aagacgctgg taaaaacacc catggtacag
    19381 atggctactc ttatgttgac ctcaaccgcc aaggggttcc cttgattgag attgtatctg
    19441 aggcagatat gcgttctcct gaagaagcct atgcttatct gacagccctc aaggaagtta
    19501 tccagtacgc tggcatttct gacgttaaga tggaggaagg ttcgatgcgt gtggatgcca
    19561 acatctccct tcgtccttat ggtcaagaga aattcggtac caagactgaa ttgaagaacc
    19621 tcaactcctt ctcaaacgtt cgcaaggggc ttgaatacga agtccaacgt caagctgaaa
    19681 tacttcgctc aggtggtcaa atccgccaag aaacacgccg ttacgatgaa gctaacaaag
    19741 caaccatcct catgcgtgtc aaggaagggg ctgctgacta ccgctacttc ccagaaccag
    19801 acctacccct ctttgaaatt tctgacgagt ggattgagga aatgcggact gagttgccag
    19861 agtttccaaa agaacgtcgt gcgcgttatg tatctgacct tggtttatca gactacgatg
    19921 ctagtcagtt gactgctaat aaagtcactt ctaacttctt tgaaaaagct gttgccctag
    19981 gtggtgatgc caaacaagtc tctaactggc tccaagggga agtcgctcag ttcttgaatg
    20041 ctgaaggtaa aacactggaa caaatcgaat tgacaccaga aaacttggtt gaaatgatta
    20101 ccatcatcga agacggtact atttcatcta agattgccaa gaaagtcttt gtccatctag
    20161 ctaaaaatgg cggtggcgcg cgtgaatacg tggaaaaagc aggtatggtt caaatttcag
    20221 atccagctat cttgatccca atcatccacc aagtctttgc cgataacgaa gctgctgttg
    20281 ccgacttcaa gtcaggcaaa cgtaatgcag acaaggcctt cacaggattc cttatgaggg
    20341 caaccaaagg ccaagccaac ccacaagttg cccttaaact acttgcacag gaattggcga
    20401 agttgaaaga aaactagaca gaacaaaacc agccctaagg ttggtttttt cttctctacc
    20461 aactcccaat aactattttg gctttatttc cagagtattt tatggtaaaa tgaagagtaa
    20521 taatatttat taaagaggta aaaacatgat tgaagcaagt aaattaaaag ctggtatgac
    20581 ctttgaaaca gctgacggca aattgattcg cgttttggaa gctagtcacc acaaaccagg
    20641 taaaggaaac acgatcatgc gtatgaaatt gcgtgatgtc cgtactggtt ctacatttga
    20701 cacaagctac cgtccagagg aaaaatttga acaagctatt atcgagactg tcccagctca
    20761 atacttgtac aaaatggatg acacagcata cttcatgaat acagaaactt acgaccaata
    20821 cgaaatccct gtagtcaatg ttgaaaacga attgctttac atccttgaaa actctgatgt
    20881 gaaaatccaa ttctacggaa ctgaagtgat cggtgtcacc gttcctacta ctgttgagtt
    20941 gacagttgct gaaactcaac catctatcaa aggtgctact gttacaggtt ctggtaaacc
    21001 agcaacgatg gaaactggac ttgtcgtaaa cgttccagac ttcatcgaag caggacaaaa
    21061 actcgttatc aacactgcag aaggaactta cgtttctcgt gcctaatctc tagaaagagg
    21121 tcattctatg ggaattgaag aacaacttgg cgaaatcgtt atcgccccac gtgtacttga
    21181 aaaaatcatt gctatcgcta ctgcaaaggt agagggggtt cactcttttt caaacagatc
    21241 agtgtctgat accctttcaa aactttcact cggccgtggc atttatctta aaaacgtgga
    21301 cgaagaactc acagcagata tctatctcta ccttgagtac ggagtaaaag ttcctaaggt
    21361 agcggttgct atccagaaag ctgtcaaaga tgccgtccgt aatatggctg atgtagaact
    21421 cgctgctatc aatattcacg ttgcaggtat cgtcccagat aaaacaccaa aaccagaatt
    21481 gaaagatcta tttgacgagg acttcctcaa tgactagtcc actattagaa tctagacgcc
    21541 aactccgtaa atgcgctttt caagctctca tgagccttga gttcggtacg gatgtcgaaa
    21601 ctgcttgtcg tttcgcctat actcatgatc gtgaagatac ggatgtacaa cttccagcct
    21661 ttttgataga cctcgtttct ggtgttcaag ctaaaaagga agaactagat aagcaaatca
    21721 ctcagcattt aaaagcaggt tggaccattg aacgcttaac gctcgtggag agaaacctcc
    21781 ttcgcttggg agtctttgaa atcacttcat ttgacactcc tcagctggtt gctgttaatg
    21841 aagctatcga gcttgcaaag gacttctccg atcaaaaatc tgcccgtttt atcaatggac
    21901 tgctcagcca gtttgtaaca gaagaacaat aaaaagaaaa agtgtttgat atctatcaaa
    21961 cactttttct ggctcccact atctaaaaaa atgataatag atataattgt aaacaaaaat
    22021 ccagataggt tttgcatgat tgagaaagtt aaaaaaacta tggcagagaa tcgttaatct
    22081 cagattgtcg gtagaacgat aaacaagggc aaaaaagaaa ccaatcagac tataatataa
    22141 taaactaatt ggatctctgt gagatagtat caaatggcta atcccaaaga taaggcctga
    22201 taagatgaca tctaaatagt actttgactt aggaaagaag gtattcataa aataccctct
    22261 atcaagagtc tcctcaaaaa caggaccgat gattacaagc aggacaaaag ataagatagt
    22321 cgataaaaag gttggttgtc catttgaaag aaccacggta aaatactcat catgaatatt
    22381 cctatggtta atcaaatgag catagcgtgc ctaaaaatta ccgagaatct gataaaccac
    22441 ataagttgca aataagtaga agacaaatga ccagttccag ctcttttttt caaagataaa
    22501 gagcatcttt ttctttttta acctccaaat taatagaagg aaacttccca ctaataccat
    22561 tgttaaaata agagaataga catcagctcc taaccctaaa atgatcgtca catacaatcc
    22621 aattgtttgt ggtaaatagg tagatagtaa aataataagc aaaaatattc caaattgtct
    22681 tagttttttt gtgtttctca tcgtactttt ttgaaagatt accctgctcg gaagccgtac
    22741 ttccaagcat ctatataaga attaagtgcc ccttgcctca tatagggagc aaattctcta
    22801 taatataacc atctactata tccatcttcc caaacagcaa gaccacctga agtttgctcc
    22861 aagtcctcag ttgaaagaac tgtaaatgta tttgtacctg tcattgcaag taccttctta
    22921 aaatatagtg atttgaaata agatgtaaac aactctatca ggaaagtcaa attaatttat
    22981 agaaatattt tagcagtcaa ggtgtactgt tatagattca atacactata aatttttgta
    23041 agcttacatc tacagtatac atcttttttg tctattttat agtctatctc ctcaactgtc
    23101 aagttttcaa cctgaattgc atttttccat aaaaaatgag acctttctag tctcatttag
    23161 tcattcttag tattttctaa atcgttgata gcgttcttcc agcaactctt ctagcggttt
    23221 ttgtgaaagt ctagccagct ccgtttggag ttcttttttg acactcttaa tcagttcttt
    23281 actagaaagt cctacttcag aaatcacctt atccaccacg tccatttcta acagttcatg
    23341 cgaagtgatt ttcatcagtt ctgctgcttc catggcgcga gtaccgtcct tccataaaat
    23401 ggaagcaaag ccttctggac tgagaatggc atagatagaa ttttccagca tccagacacg
    23461 gtccgcgaca gctagagcca gagccccgcc tgaaccacct tcaccgataa taatggcgat
    23521 aataggaact ttcaggtcac tcatttccat gagattgcga gcgatagctt ccccttgacc
    23581 acgttcttct gctccgacac caggataagc acctgctgta ttgataaagg tcacaactgg
    23641 acggccaaat ttctcagcct gtttcatcaa ccgcagtgcc tttcggtagc cttctggatg
    23701 tggttggcca aaattccgtt tgaggttgtc ttgcaaactc ttgccttttt ggataccaac
    23761 cactgttaca gcttggtctc caagccaacc aataccacca acaactgcac catcatcacg
    23821 aaaagaacgg tcaccatgta attggataaa ttcatcaaaa atgcctgtcg caaagtccaa
    23881 ggttgtcaag cgactctgct cacgcgcttc tctgactatt tttgcaatat tcatctagga
    23941 ctccctccat gcaatctgac taggctagca atcgtatctg gtaagtctct tcttttgaca
    24001 atagcatcca caaagccatg ttctaatagg aattctgcct tttggaaatc ctcaggcaag
    24061 ctttcacgaa ccgtattttc aatcacacga cgcccagcaa aaccaaccaa gctctgtggt
    24121 tcagccagaa tgatatcgcc ttccatagcg aaagaagctg tcacaccacc agtcgttgga
    24181 tctgtcaaaa tagtcaggta aaagagacca gcatttgaat gacgtttaac cgccgcagag
    24241 atcttagcca tctgcatgag actcatgatt ccttcctgca tacgggctcc accagaggct
    24301 gtgaatagga caactggcaa tttttcgaca gtcgcatact caaacaaacg agtgattttt
    24361 tcacctacaa ccgtacccat agaagccatg ataaagttag aatccataat cccaagagcc
    24421 acagtctgac ctttaataag agcagttcct gtcacaacgg cttcatgcag acctgttttt
    24481 tcacgcatag atgccagttt cttttggtaa ccagggaaat gcaagggatc cttgctttca
    24541 atccctgtaa acaattcttt gaaggttccc atatcaatcg tcaaagccaa gcgttcttgg
    24601 gcagaaatac gaaaggtata gctacagtgc ggacagatac gttcacttcc cagatccttc
    24661 tgatagatgg tatgcttaca gcctggacac tgggaaaata attcatctgg aacctctggc
    24721 ttagcttgag gtttttccct aaccgaacga ttgggattga ttcgaatata cttatctttt
    24781 ttactaaata gagccattga ttcccctttt cggtttaaac tcttaaagtc attttattct
    24841 ttttcttgat atttaggtaa gaaggtttcc atcaagaagg aagtatcata atccccagca
    24901 atgacattgc gatctgaaat gaggtcaagc tggaaatctg cattggtctg cactccttca
    24961 atctctaatt catagagggc acgttgcatt ttcatcaagg cgtcaaaacg attttcgccg
    25021 tgtactatga ttttggcaat catactatca taataaggcg gaatggtata acctggataa
    25081 actgctgaat ccacgcgcaa gccaactcca ccacttggca gatagagatt agtaatctta
    25141 cctggacttg gagcaaagtt aaaggctggg ttttctgcat tgatacgaca ctcgatggca
    25201 tgaccgcgta ggacaatatc ttcttgctta acagacaaag gctgacctgc cgcaatgcaa
    25261 atctgttcct taacgatatc aacacctgaa acaaactctg ttactggatg ttctacctga
    25321 acacgagtat tcatctccat gaaatagaaa ttgctacttg cttcatcaag aagaaattca
    25381 atggttcctg cattctcata gccaacaaac tctgccgctc gaacagcagc agcacctatt
    25441 tcatgacgca gcgtttttcc gattgcaatc gagggacttt cttccaaaac cttttggtta
    25501 ttcctttgaa gagaacaatc ccgttcaccc aagtgaatca catgtccatg ctcatcacct
    25561 aggatttgaa cctcaatgtg ccgagctgga tagataaccc gttctatgta catggcacca
    25621 ttgccataat tggccttggc ctcactagag gcagtttcaa aggcagaaac gaggtcatct
    25681 ggtttttcaa ccttacgaat ccctttacca cctccacctg ctgaagcctt gagcataaca
    25741 ggatagccaa ttttttcagc aacaattaaa gcttcttcag agttatgcac ttctccatct
    25801 gaacctggta taacaggcac acctgcttta atcatctgag cacgcgcatt gatcttatcc
    25861 cccatcatat ccataacatg accagatgga ccgataaact tgatacctac ttcttcacac
    25921 atggtcgcaa atttggaatt ttcactgaga aatccaaaac cagggtgaat agcttctgcc
    25981 tcagtcaaga ctgcagctga tagaactgca ttaatattga gataagactc tgttgccttg
    26041 ccaggaccaa tacaaactgc ttcatctgcc aaaagcgtat gaagagcttc cttatcagca
    26101 gttgaataaa ccgctaccgt cgcaatcccc aattcacgtg ccgcacggat aatacgaacc
    26161 gcaatttcac cacgattggc aattaaaatt tttcgaaaca tggagaacct ccttagttcc
    26221 caattgcaaa agtaagggta ccactggctg caagcttgcc atccacttca gcctttgctt
    26281 caaccacagc tatggtgcca cgacgtttta caaaagtcgc tgtcataacc aattggtcgc
    26341 ctggtacaac ttgcttcttg aacttaacct tgtccatacc agcgtaaaag accagttttc
    26401 ctttattttc aggttttgat aactccaaca caccggcagt ttgcgccaag gcttccataa
    26461 tcagaacacc tggcataact gggtattgag gaaagtggcc gttaaagaaa ggttcgttaa
    26521 tggtcacatt tttgatagca acaatggtat cctcgctcac ttccaagaca cggtccacta
    26581 gaagcatagg ataacggtgg ggaagggctt ctttgattcc ttgaatatcg atcatttgat
    26641 acgtaccaat cctttaccaa actcaaccat ttcttcgtta gagacgagaa tttccgttac
    26701 cacaccatcc ttaggagctg ggatttcatt catgactttc atggcttcga taattaccaa
    26761 tgtttgacct tttttgacac tatcaccaac tgtaacgaag gcaggtttat ctggtccagc
    26821 agccaagtaa accactccaa caagtggact ctctacaaga tttccctcag tagccacact
    26881 tgcttcagct ggagctggaa cttcttctgc tacagtctct gctggagcag atgtaggagc
    26941 tactggactc ggtgttgcta gaacgggtgc tggagcgact tgagttgcaa cttcaggcac
    27001 aggtctcgct tcattcttgc taaactgcaa ctcatccgtc ccatttttat aagaaaattc
    27061 tctcaaactt gactggtcaa attgagtcat caagtcttta atatcgttta aattcatact
    27121 tatctattct cccaacgttt gaaagcaaga actgcattgt ggcctccaaa accaaaagta
    27181 tttgaaatag cgtatggaat ttctttctcc aagccttgtc cataaacgac attagcttcg
    27241 atataatctg atacttcact tgtcccagct gtcattggta caaagttatg acgcatagct
    27301 tcgatggtga cgatagcttc tactgcaccc gcagccccca gcaaatgtcc tgtaaaagac
    27361 ttggttgatg atacaggtac ttccttacca agaacagcta cgatagcacc actttctcct
    27421 ttttcattgg caggagttga cgttccgtga gcattgacat aggctacttg ctctggagaa
    27481 atctcagctt cttccaaggc tagtttgatg gccttgatag ctccctgacc ttctggatgt
    27541 ggagaagtca tgtggtaggc atcacaagta tttccgtaac caaccacttc agccaggata
    27601 gtagctccac gtttttcagc gtgttcaaga ctttctagaa ccaacatccc tgaaccttca
    27661 cccataacaa acccattgcg atccttatca aatgggatcg aagcacgagt tggatcctct
    27721 gtagtagaga gagctgttaa ggcttggaaa ccagcgatgg caaaaggtgt gatagaagct
    27781 tctgttcctc ccaccaacat cacatcttgg aaaccaaact taatggagcg gaaggcatcc
    27841 ccaatcgcat catttgatga agagcaggca gtattgatag atttacaaac accgtttgca
    27901 ccaaaacgca tggctacatt cccagaagcc atatttggta aagcttttgg aagagtcatt
    27961 ggtttgacac gtttgggtcc tttttcatga aggcgaagta cctgatcttc aatttccttg
    28021 attccaccaa taccagatgc aacgataaca ccaaaacgat ccctattaag agcctctaca
    28081 tcaagattgg catggtttac agcctcttgg gctgcataca aggcatataa agaatagtta
    28141 tcaaaacggt tggtatcttt ttttacaaag tatttatcga acggaaaatc ttggatttct
    28201 gccgcattat gcacatcaaa gtcactatga tcaaattttg taatgccacc aatgccgatt
    28261 ttcccagttg ctaaactatt ccaaaattct tctggtgtat ttccgattgg agatgttact
    28321 ccataacctg ttaccactac tcgatttagt ttcattcttt tcacctctag ctttcgctac
    28381 atacttaagc caccatcaat ggcaatcact tgaccagtta gataatcttg gcctgctaaa
    28441 aatactgtca aatctgcaac ctgctctgcc tgcccaaatt ctttcatcgg aatctgagct
    28501 agtgtagctt ccttaatctt atctgataag atagcggtca tatcagactc aatcattcct
    28561 ggagcaatca cattgactcg tatattccga ctagcgacct cgcgtgccac agacttggta
    28621 aagccaatca agccagcctt agaagcagca tagttagctt gaccaatatt ccccatcaaa
    28681 ccaacaacac tagacatatt aatgatagca ccttctctgg ctttcatcat cggtttcaag
    28741 actgattgtg tcatattaaa ggcaccagtc agattgacct tgagcacttt ttcaaaatct
    28801 gcttctgtca tcttaagcat aagagtatct tgggtgatcc ctgcattgtt gaccaaaaca
    28861 tctactgaac ccagttctgc aatagcttga tcaatcatac gcttagcgtc tgcaaaatct
    28921 gatacatctc ctgaaatggg aaccaccttg ataccatagt ttgaaaactc agcgagcaat
    28981 tcttctgaga ttgccccacg actgtttaag acaatgttgg ctcctgcttg agcaaacttg
    29041 tgggcgatgg caagaccaat tccacgactc gaacctgtaa taaagatatt tttatgttct
    29101 agtttcattt ttttcctttc aaaacttcta cttattttag tctatttttc taaaagtgct
    29161 actaaactcg cttgatcttc cacatgagct aagtgagcag ttcgatcaat ttttttaaca
    29221 aaacctgaca aaactttccc cggtccaatc tcgataaagt tgcttatgcc tgcttcttgc
    29281 atgaccccaa tactttcata gaaacgaacg ggttccttga cctgacgcgt caagagctga
    29341 gcaatgtcct ctttttgcat cacagcagct tctgtattgc cgactagggg acaagtaaaa
    29401 tctgaaaaac ttacctgagc tagagtttca gctagtttct ggctagcagg ttcaaggaga
    29461 gcggtgtgaa agggacctga caccttaaga ggaatcaagc gtttggcacc tgcttcttgc
    29521 aaaagttcaa ccgctcgatc aactgcaacc acttctccag caatgacgat ttgtgcaggt
    29581 gtgttatagt tggctggagt aaccactcca agttcagaag ctttttgaca ggcttcttca
    29641 atgacctcta ctggcgtatt gagaactgct accatcttgc cagagtcagc aggagccgct
    29701 tcttccatat aggctccacg cttagctacc aaggcaaccg catcttcaaa atccaaggcg
    29761 ccgcttgcca ccaaggcaga gtattctcca agagacaaac cagcaaccat atcaggctga
    29821 tagccctttt cttgcaataa acggtagata gcaaccgaag tcgctagaat ggctggttgc
    29881 gtatagcggg tctgattgag tttgtcctct tccgtatcga tgagataacg caaatcataa
    29941 cctagcacct gactcgctcg atcaatcgtt tctttgacaa tcggatactg atcatagaaa
    30001 tcccgtccca tccctagata ctgggcacct tgaccagcaa ataaaaaggc tgttttagtc
    30061 atttcttaca actcctgccc agcgagaggc ttcttcttga attttcttag cggctccgta
    30121 atacaaatct tttaggattt cttcagctgt ttcttcttta gaaacaagcc ctgcgatttg
    30181 acctgccatg acagagccac catccacatc accgtgaaca actgctttgg ctagggcacc
    30241 tgctcccatt tgttcaaaga tttctaaatc aggatcttcc tgcttaaagg catctttttc
    30301 agccagttca aaatctctag tcaactgatt tttaatagca cgaacagcat gaccaaagtg
    30361 ctgagctgaa atcgtagtat caatatccct tgcttttaaa attttctcct tgtagtttgg
    30421 atgggcattc gactcttttg caactacaaa ccgtgtcccc acctgtacag cctctgcacc
    30481 tagcataaag ccagccgcag caccttcacc atccgcaatt cctcctgcag caataacagg
    30541 aatagataca gctgtggcta cctgtcgcac caaggtcatg gttgttaatt taccgatatg
    30601 ccccccagct tccattcctt ctgcaataac agcgtctgca ccgatttttt ccatgcgttt
    30661 agctaaagcg acactaggaa cgacaggaat aacgattatc ccagcttcat ggaaacgttc
    30721 catatacttg cttggatttc ctgctcctgt tgtgacaact ttaacacctt cttcaataac
    30781 gagatccacg atatcttcca caaagggaga taagagcatg atgttgaccc caaagggttt
    30841 atcagtcaat gatttgattt tatcaatatt agccttgaca acttctttcg gggcatttcc
    30901 cccaccgata attcctaatc ctccagcctt ggaaacagcc cctgccaaat caccatcagc
    30961 aacccaggcc atccctcctt ggaaaatagg ataatcaatc ttcaataatt ctgtaatacg
    31021 cgttttcata gtgcctccaa ccttccttgc ttacgtaata gttcgatttc accataattt
    31081 gacagtcaaa ctattaccta aacaagaggg agtgggtttc tccctactcc ttctactaat
    31141 attctgctta ttttgcttgc tcttcaacgt aagcaaccaa gtcaccaact gttttcaagt
    31201 cattttctgc ttcgatttgg atatcaaaag catcttcgat ttctgagatt acttggaaca
    31261 agtccaatga atctgcgtcc aaatcatcaa aagttgattc aagtgttact tctgatgcgt
    31321 cttttccaag ttcttcaacg ataatttctt gtactttttc aaatactgcc atgataggac
    31381 tcctttaaaa taaatagttt ttttataaca atgtgttcac cacatgatta cctaaattgt
    31441 aagaatgagc gtgccccagg tcaagcctcc accgaagcct gatagaagaa cagtctggct
    31501 accatctaaa gggatgagac cttgttctac acactctgaa agtaaaatcg ggatactggc
    31561 tgcactggta ttgccatatt ccatcatatt ggctggaagt ttggctcggt caacaccaat
    31621 ttttctagcc atcttatcca aaatacggtc attggcttga tgaagtagca gataatccaa
    31681 gtctgtcacc tctataggag attcatcaat agtctgcttg atagacttgg ctacatctcg
    31741 aatggcaaaa tcaaagactg tgcgtccatc catcttcaaa aatgaatctg cactttcttg
    31801 atctgaaaat ggagaatgca aacctgaatg cccataagtt aaacactcgc tgcgacttcc
    31861 atcgctattg agactctcag ctaagaaatg ctcttgctcg ctagcttcta acaagacacc
    31921 accagcacca tctccaaaca acacagctgt tgatcgatcc gaccaatcga ctgccttaga
    31981 gagggtttca ctaccaatca ccaagccttt ttgaaagcga ccagaagcga taaacttttc
    32041 agcagttgaa agagcaaata caaatccact gcaagccgcg gttaagtcaa aagcaaaggc
    32101 tttattagcg ccaatattag cttgaacacg agcagctgta gagggcatca tcgaatttgg
    32161 agtaatggta gctaggatga taaaatccag ttcttctcct gttattccag cttttgccat
    32221 cagtttctta gcaacctctg tagccaaatc actggtagat tctgttcttg aaatatgcct
    32281 ttgtcgtatt cccgttcgac ttgaaatcca ctcatcattg gtatccataa tctgagccaa
    32341 gtcgtgattt gtaaccactt gctctggcac ataatgagca acctgactta tttttgcaaa
    32401 agccattatt tcaaatcctc caaaaattgg taaagattag tcaagccttt acccatgaca
    32461 gcaatttctt cctcgctcat gccatcaata attttttcta ccatggcctt gtggaagcgt
    32521 ttatgcagtc tatgaatcaa gcgacccttc tttgtcaaat gcagatgcac cacacgacga
    32581 tcctgttctg accgaactcg ctcaatgtag cccttacgct ctaaattgtt caaacttgtc
    32641 gtaacagttc caagagttac catcaactct tttgacactt gacttggagt cacatctgga
    32701 gccttaccga tgacatcaat cgtatgcatt tctttgatgg agatatcctt aaaacgacta
    32761 cctctcaagt tcacttcctc aattacaagg acattgttaa atatagatgt taaatattca
    32821 ttgattcgtt ggtagtccat ttttcatatc cctccttctt caaaaaactt ttacaatcaa
    32881 aacatttgac agaaagaatt atatcaaaat tcaaagaatg atgcaaggat tttttatttt
    32941 cctgtaaatt taggtcttct tctctccgaa tgagctcgca ctccttcttt gaaatcctct
    33001 gtttgagcta aggatttctg taggttcagt tctaaagtag cgtaaccctg ccagtcttta
    33061 aattggctct cccaaaccaa cttcttaatg gcagcatagg aattacttga agcacgtctt
    33121 aattttttaa gaagctgttc tctcgtcttt tcaagttttt cagcttcaga aacgcggtaa
    33181 accaaccccc attctagggc tttttctgcc gttaaagcct ctcctgtcat agctaattga
    33241 gcagcacgcg tcacaccgat actgcggctc aagagatgaa ttccccctgc atctggagcc
    33301 aaaccaacac caacaaaggc ttggataaac ttagccttat ccgtcgccaa acagaaatct
    33361 gccgcaacag ccatattcgc tgcggcacct gcaacagcac cgtcaacttc cattaaaaca
    33421 ggtttggcta tttgcttgat tttataagaa atcgtattga ccaactctgc gatttttgtc
    33481 aatgatggaa tatcatcctc atccactgcc cgcttcatct ctaccaaatc tcccccaact
    33541 gagaagacct ttccattggc attgattaag ataaaatgca cagctggatt ttcttctgcc
    33601 aaagtcagag cttctaaaat ctcctcacac atgggaatat gaaaaccatt tgcgacctca
    33661 ggacggttca aggtaaggat tgccaagtcc tcttcaagct gataaataat gtgttccatc
    33721 agggctcctt tttattttat aagcagttta tactcttcga aaatctcttc aaaccgcgtc
    33781 agcttccatc tgcaacctca aaacagtatt ttgagctgac ttcgtctagc ttcttagttt
    33841 gctctttgat ttttattgag tgttaaatta tttcactgtc aaagtatatc ttttttagga
    33901 gcagaaagca agaaaaaatc gactgaaagt gtctcagccg ataagaaagg ctcgctttag
    33961 gctagaaagc atcttatttt cttcattgaa aaaagccttt ctttctgcta taatcgtata
    34021 aaatacttac tttaggagtt cttatgaaag ttgttaaatt tggaggtagt tctcttgcct
    34081 ctgctagtca attagaaaaa gttttaaaca tcgtcaaaag cgattcagag cgtcgtttta
    34141 tagtcgtttc tgcgcctggt aaacgcaatg ctgaagatac taaggttacg gatgccctga
    34201 ttaaatacta ccgcgactat gttgcgggta acgatattag caagagccaa agctggatta
    34261 tcgaccgcta tgctgctatg gttagtgaat tgggactaaa accagctgtg ctagaaaaaa
    34321 tttctaaaag tattcacgcc ttggccgctc ttcctattga agaaaatgaa tttctctacg
    34381 atactttcct agcagccggt gaaaataaca atgccaaatt gattgctgcc tactttaacc
    34441 aaaatggtat cgatgcacgc tatatgcacc ctagagaagc tgggattgtg gtcacaagtg
    34501 aacctggtca cgctcgcatc attccatcaa gttatgacaa gattgaagaa ttgacaacca
    34561 ccaatgaagt ccttgtcatt cctggtttct ttggtgtcac taaggaaaat caaatctgta
    34621 ctttctcacg tggaggttct gatattacag gttctatcat tgctgctggt gtcaaagccg
    34681 acctctatga aaactttacg gacgttgatg gtatctttgc agcccaccct ggtattatcc
    34741 accaaccaca ctcgattcct gagttgacct accgtgaaat gcgcgagttg gcctatgcag
    34801 gcttctcagt ccttcatgac gaggctcttc ttcctgccta ccgtggaaaa attcctctgg
    34861 ttatcaagaa taccaacaac cctgaccatc caggtactcg tatcgttcta aaacacagta
    34921 atgatgaatt tccagttgtg ggaattgctg gtgactcagg ctttgtcagc attaacatgt
    34981 cgaaatacct catgaaccgt gaggttggat ttggccgcaa ggttctgcaa atcctggaag
    35041 aacttaacat cggttgggaa catatgccaa caggtatcga cgatctttct atcattctcc
    35101 gttctcgcca actaactccc atcaaggaag aagaaatcct gcgtcagttg gttcaaaagg
    35161 ctaaagtaga tcatgcagaa atcgaacacg acctttctat cattatgatt gttggtgaaa
    35221 aaatgaagag ccatatcgga gtgactgcta ctgcgacacg cgctctatct gaaaacaaaa
    35281 tcaacatcca gatgatgtct caaggttcta gtgaagtttc tattatgttt gttgtcaata
    35341 aagaccaaga gaaagcagca attaaagccc tctacaatgc cttttttgga gaaagtaagg
    35401 aagactaagc atggctcaat cacttaacaa aacagtactc ctcagtacga caggcacttc
    35461 ctacctctct atcgctggga aagttgggaa attccttgtc ggagatcagg ctttggaatt
    35521 ttacccagat gtcaatgtcg aacaatttat ccagattcct tggagccata tcaatcagat
    35581 tggagccaat gtcactggac gcaaaatcag ccgccacttc gaagtcttta cagacaaagg
    35641 aaaattcctc tttgcttcaa aagactcagg tgccattctc aaaattgcac gcaaaaaact
    35701 aggcaatgac aaggtcgtca aacttccgac cctgattcag acaattagcc aaaaatttaa
    35761 aaatctattt gcaaaaaagt agaaacttta gtataatcat agcaacggat aagtaggtta
    35821 tcttcttctt tcagaaagtc tgcgggtact gcgagcagat aggagggata ggtgaaattc
    35881 taccgttagt aacaattaca tacacaatca agtgcacacc tgtgaagttg gatggaaccg
    35941 tggccctgcc actccaacgt tttgtcaggc gtgctttttt cataaaggag ttcttatgtt
    36001 agatatcaaa cgtattcgta cagattttga agctgtcaca gaaaaattag ctacacgtgg
    36061 tgtagatgct gctgtcttga atgaaatgaa agaaatcgat gctaaacgtc gtaacatctt
    36121 ggtcaaggtt gaaactctca aagcagaacg taacacagtt tctgctgaga ttgcccaagc
    36181 taagcgcaac aaggaaaata cagatgacaa gattgctgcc atgcaaaatc tatctgctga
    36241 ggttaaagcc ttggatgctg aattggcaga aatcgatgct aaattgacag aatttacaac
    36301 gactcttcca aatatcccag ctgacagcgt tcctgttggg gctgatgaag acgacaatgt
    36361 ggaagttcgc cgttggggta ctccacgcga gtttgacttc gaacctaaag ctcactggga
    36421 tctcggtgaa gaccttggta tccttgactg ggaacgcggt ggtaaggtaa caggcgctcg
    36481 cttcctcttc tataaaggcc tcggtgctcg tttggaacgt gctatctaca actttatgtt
    36541 ggatgaacat ggaaaagaag gctatactga agtcatcaca ccttacatag tcaaccatga
    36601 ttctatgttt ggtactggtc agtatccaaa atttaaggaa gatacttttg aactcagcga
    36661 taccaacttt gtcttgattc caactgctga agttcctctg gcaaactact accgtgatga
    36721 aatcttagac ggcaaagatc ttccaatcta cttcactgct atgagtccgt cattccgttc
    36781 tgaggctggt tctgccggtc gtgatacgcg tggcttgatc cgtttgcacc aattccacaa
    36841 ggttgaaatg gtcaaatttg ccaaaccaga agaatcttac gaagaattgg aaaaaatgac
    36901 agccaacgct gaaaacattc ttcaaaaact caaccttcca taccgtgtcg ttgctctctc
    36961 tactggagat atgggcttct cagctgcgaa gacttacgac ttggaagtgt ggattccagc
    37021 acaaaacaat taccgtgaaa tctcaagctg ttcaaacaca gaagatttcc aagcccgtcg
    37081 tgcccaaatc cgttaccgtg atgaagcaga tggcaaggtg aaactccttc ataccttgaa
    37141 cggttctgga cttgcagttg gacgtacagt ggctgcaatt cttgaaaatt accaaaatga
    37201 agatggttct gtgaccatcc cagaagcact tcgtccatac atgggtggag ctgaagtcat
    37261 caaaccataa aaaataaggt ttagctattt ctagctagac cttttttcgt aaccaaatca
    37321 gataatcacc tagtacaaag aataaaatag ttaggcatat aatggtttca gccaatacca
    37381 ggtaatccag aaatggaagt ttcaaaattc cctgagccat cttgagcgag gtcgctgtga
    37441 taatggttgg gaaggtgagg gctgagaagg ctggttgaaa accttgtttt aaaatgttgg
    37501 gcagacgagt taaaacaaag aaaaagaagg attgagaagc caaaatcatg acaatcaaga
    37561 cccaagtcgg caggctggtt cctcctactc gaactagaga agccaagagt agagagaaag
    37621 gagcacagta gattccttct tgtccaagca aggctagtgg gagtggatgt ttctttaaat
    37681 cgctataaat aaggggatag agatagaagg tcaagagaaa accaaaactt aaggtcgcat
    37741 aggcaatttc gataatacct accagaggat aggtcaaggc agccactgct atccccacat
    37801 agagaaccgt ccagcttgga gtggcatgaa ccctccgccc tggacaagca aacttgatgg
    37861 taaaaccagc aatcaaggtc aaatccaaga gaaatgaaaa ccaccaaatc ccttgtgcta
    37921 ccaaaggaag ataagagaat acgcgaaaga cataggtcga taaaatcatc ccagccatag
    37981 gaaaggttgc cattcctgac aaaagagggg gcttggtcaa ttcttgcttg gtttctttcc
    38041 aattaaagag atgcagaatt agaaagtaaa tccataaaac caaaccagtc agactaaaaa
    38101 gatgggatag aaccggcaac gtatctaaaa taagatttcc agctcctgcc aaacctagca
    38161 aacaacctga aaatactaag gggagttttt tcatcctaac ctccaataat catgttagtt
    38221 tcagtataac ataaaagcga ttaaatgagg atttaaaaaa acgaagtccg cttatttcag
    38281 acttcatttt actcagatat gaattaggca taaggttgca attctggatt aattggtgta
    38341 ttagctaagt tgttggcata gttacagagg attgctaggc tgacaccaaa aaccacatcc
    38401 aaggcatttt gttgagtgta gccagcttct aaaaactcag acaaggcttc atctcctaca
    38461 cgacccttgg tattgataac tgccaaggta aacttagcta gggtatccaa tttaggatct
    38521 gtttcaattg gagtacgatt gcgaagagct tgaatcaagt catcattcat ctggatttgt
    38581 ttgatggaaa aggctgtgtg acctgcgaca cagaaggcac aaccattggt cacggctgcc
    38641 gtgatttgca ccacttcacg ctcaacgggt gtcaggctgt tgcgacggtg gatagatgag
    38701 acaatttggt aggcttctaa aacagtcggg gcattggcca agagaccgat taggttggga
    38761 atatagccat tgttgtcttt ttctactgtt tcaagaattt ctttcacttc tgctggtgct
    38821 gactctactg tatggatagt aaatgttgtc ataagatacc tcttttctta ttattgacac
    38881 taatattatt ggaaaatctt ataaaatcct gattcctaag tttatctaag ataaagcttt
    38941 attctctcat aagattttcg ttgttatatt agtttatcac acttccaatc acttgcataa
    39001 tatatattat atatcaggct gataaaaatt atttataggc aaaaaaatca cacgagctgt
    39061 gtgattccat tatttgttaa aatacttttt agtttcagca ataacgactg gcgacaagac
    39121 caagagggca atcaagtttg gcagagccat caaggcgtta acgatatctg cgataatcca
    39181 gaccatatcc aactcgataa atcctcctaa caagaccatg agcacaaaaa acacacggta
    39241 gagccagata aagcgagccc caaagaggaa ctcaaaacag cgttctccgt aatagttcca
    39301 acctagaatc gttgtaaagg caaaaagtac aaggaagatg gtcaagaggg caggcccaaa
    39361 gtgtgaaaag actgttgaga aagctgactg agtcaaggca accccattca agtcaccact
    39421 ccaaactcca gttaccaaga tggtcaaacc agttagagta caaatgatga gggtatcaat
    39481 aaaggttcct gtcatggaaa tcaaaccttg ctctactggt tcatttgtct tggcagctgc
    39541 agctgcaata ggagcagaac ccagaccaga ttcgtttgag aacacaccac gcgccacacc
    39601 attttgaata gccatccgaa cgctagcacc agcaaatcca cctaccgcag caaggggact
    39661 aaaagctgag gtaaagacta aagcgattgt gccagggatt tttccgatat taaagaaaat
    39721 aactgtaaga gttcctaaga tataaatgag ggccataaaa ggaacaacag tagttgaaac
    39781 cttagaaata gacttgagtc caccaaagac tgcaatcgct acaaagacag acaagacgag
    39841 agctgtgatg gctggcgaaa tcgtcgttgt attttggata gattctgtaa tcgagttgac
    39901 ttgggtgaag gttccgattc ccaagagagc aaccaatact cctgctactg caaacaaaac
    39961 agcaagtggt cgccactttt ctcccatccc tagaaggata tagtgcatgg gacctcccgc
    40021 tactgcacca tggtcgtcct tggtgcggta tttgatggcc aagagtcctt ccgcatactt
    40081 ggtagccatt ccaaagaaag ccgccatcca catccaaaat agagctcctg gtccaccaac
    40141 cttgatagcc gtcgcaactc ctatgatatt tcctgttcca acagttgatg ccaaggctgt
    40201 acacagagct gcaaaactgg atacatcacc atgtccctta tcctggataa aaataagctg
    40261 aaaggccttg ggcagacgca aaacctgcaa gagtcctagc cgcatggtta ggtaaatccc
    40321 tgttccgacc aataaaatca agaggggcgg tccccaagca aaagcatcga ttgatttaag
    40381 caattctaac atttccttct cctatcgttt caaccccaaa agaaagagca catgcaagat
    40441 acatgtactc tggaatgctt agataaatgc taaaaagcgg tctatcctag ctctgtcctt
    40501 ttacctgaga gtttgagcag ttgcctgcct tgccccttcg gtgcctttac ggtctctcca
    40561 gagttccgtc catttacagt catggaaaat caaacgattc cccacttcta ttaaacttca
    40621 ttcggtgttg gtatttaatt gattctaatt ttacaaaaaa tgttggcttt tgtcaatgtg
    40681 tttattagta aaaattagtt caacagtttt tactttataa agtccagaat actgctatcc
    40741 tttaaaagtg acaatagtcg caccactgcc tccagcattt tgtggggcat agccgaaact
    40801 cttgacatgt ttgtttcttt gcaagtattt ggtaactcct tcacggatga ctcctgttcc
    40861 gataccatgg atgatatcaa cttgagccat attgttaagc aaggcttggt cgatgaaggt
    40921 atctagctca ttcatggctt cttcatagcg cttgcctcga agatccagtc tagcttgagg
    40981 tcctcgccca gaagttcgtt tcacaacatt gacctgtttc ttcttgactg gtttttcttg
    41041 ctgggcttga acaagatcaa actctttctc ttccaaggtc atcttaatca agccaacttg
    41101 ggcttcccag cggccgtcct tgagttgact ggtcaaggta ccacgctgac cataactgag
    41161 aaccacgata tcatctccca cctttggagc tcgttttttc ttggcctttt gaaggacctt
    41221 gtttttagac aagtccactt tttcaggagc caattttttc aacttggcct tggcttcaat
    41281 gatttcgtgg ggcttgagtt gggatttact gtggagattt ttgagaatct ggtcactttc
    41341 acttagggcc atatccacaa tctcagcagc ctgttcacgc gccttgttaa gctcggtttc
    41401 cttttcacga ttaagctcgt tgtagagttt ttttagcgca cggttcatct tgagattttc
    41461 ttgctccacc tcacggatat tgtccaaacg tttgcggctt tccagcgtct gctcttctaa
    41521 ttgctcaatg atacgattga cgtcattgtc ctgatcgatc tgctgactgg catctcctac
    41581 gataacttca gataggccta gacgtttggc aatttcaaag gcattacttc ggccaggaac
    41641 accctgcata aagcgatagg tcgggcgaag agttgcagta tcaaactcca tactggcatt
    41701 ttgcacaaag gctgtctcaa taccgtaggc cttgagttct ggatagtggg tcgtcgccat
    41761 ggtcttgatt tgacgcaggc gaaggtcctc cagaatagcc atggcaaggg ctgctccctc
    41821 ttggggatca gtaccagccc ccaactcatc caaaagtaag agtgaatgtt ggttgacctt
    41881 gccaagaata tccacgatat tggtcatatg gctagagaag gtagacaagc tctgctcaat
    41941 agactgctca tctccaatat cagcaaagat ttcttcaaaa ataccaacac gacttccctt
    42001 gtctgctaaa atcggcaatc ctgactgggc catgacctgt gtcaagccca gagttttgag
    42061 catgatggtc ttcccacctg tattgggacc tgtaatgaca atagctgtta aatcttgacc
    42121 aaaatagaca tcatttgcga cggcattttt gaccaaagga tggcagacat ggagcagttg
    42181 aatctcttga ttttctgaca gctgaggcac gactgcttgc ctttcttgga taaatcgaac
    42241 cttggcacga atcaagtcca gatgaccgat aatccaagcg tcattagcaa tctcagccgc
    42301 atgagggcgg acacgctcag aaatttcttg gagaatgcga agcatttcat agcgctcatc
    42361 tgctcgcaga ctagcaattt cttcgctcag tttgactacc tcacgtggtt cgatatagac
    42421 ggtgtttcca ctagcagaaa tatcatgaac gacacctgca atcttattgc ggtaggtgtt
    42481 tttgactggt aaaacctgac ggccatttct gctagcaaca attccttccg tcaacatctg
    42541 cgctttttgc ttgagtaagt cttgtaaaac atcgcgtacc tgactctcgc tatcatgtat
    42601 ttttcgacgg attcgcgcca attcttcact ggcaaaattt tcaatgaaac ccgcatcatt
    42661 aaaggcctga agatttcctt gtaattgcgg aaaatcatgt aatttctcaa accaaagggc
    42721 taattcttcc aagctgacat tttccagatt ggcgtaaaaa ttttgaagtt ctcggctggc
    42781 aagaagcacg cgtttcaaga gtaggaactc ctcgatattg agatccgctc tcatctccaa
    42841 cctcttgcag actcctgcaa tttccttagt tgagagaata gtaaaatgcg gttgctcgac
    42901 gaaaagagcc tgcatttcct tcatctcagc aaaagcctgt ttgattttat ctgctttggc
    42961 agtcggagcc agctgtctca attgctccaa gccctgctcg gtcaacaaat gaggctcaaa
    43021 caaggccttg accttatcga actctaatgt ttctaatatt ttcttattca tctttatttc
    43081 cttgtctttg aatgtctagg tgtggtagct ttttacattc tgatagattc gagtcaaatc
    43141 tgtaaacaaa gggctaggaa aactcctgcc ctttttatcc gattaaattt gtcacccaga
    43201 tttgtttgag ccaactggtt gttatcggta tgctctggat gatgtgtttt gcgacgatac
    43261 tcttttcaag aggattttgt ataactgcca tggggatggt cgccaagatt gtcaaggcca
    43321 tttgcaagac aaataaggtc accaacatgg acaagatacc tgctgaaact tggaacaact
    43381 taccacccag ttttttgcta ggaatcaagt gtaagagaag accaagcaaa cgaccaatgc
    43441 tatagacaat cccaaataca agcaagtagc cgatacctgc ataaaagacc ttatccagct
    43501 gaaagagttg atccgatggg aaaaagaaag tcccctgacc ttcctgcgaa tttgcataag
    43561 ggagcaataa atggaattgc tctccaagcc ccttataaaa ctggccagcc ataaaagccg
    43621 atgccatggc tgaaatcagg taataaacct gtaagagcag gcctctccga tagccgatat
    43681 aaaatcccca aaccaagacc aatagaagaa ggaatgaaat cataaggaat cctcaatctt
    43741 gctctgttct tgcttacaag tcacaagctt gtgacggagt tcttcgagct cttgctcctt
    43801 atcgtcaaat tcaatctcac ggctgagctg agttgataaa cagttgactg ccaacaaaag
    43861 agcgattgtt tcatcatctg cgctaggcat ttgttcttta attgcttggt atttttctgt
    43921 cgcaacctta gcgatttcct ccataaaaag gttatcatgt tcgcttgtca aggttaacga
    43981 ttttttcccg aatgtaaatt tgaatcgatt tagatttgcc ataaaattca cctcacgata
    44041 ttataccaaa attcgctaat tttgtcagtt tttacaaatt ttactgcttt tgtggtacaa
    44101 tagaaactat ggcaagtatc acactcacac caagcgaaaa ggatattcag gcttttcttg
    44161 aacactatca aaccagtctg gctcctagca agaatcccta tatccgctac tttttgaaac
    44221 tacctcaagc aacggtttct atctatactt ctggaaaaat cttgcttcag ggtgaagggg
    44281 ctgaaaaata cgccagtttc tttggctatc aagctgtaga gcaaaccagc ggacaaaatc
    44341 ttcctttaat tgggacagat gaggtgggaa atggttccta ctttggtggg cttgcagttg
    44401 tggctgcctt tgtcacacct gaccagcacg actttttacg aaaactcggt gtgggggatt
    44461 ctaagactct gaccgaccaa aagatccgtc agattgctcc tattctcaag gaaaaaattc
    44521 agcaccaggc actccttctc tcacccagca agtacaacga ggtcatcgga gaccgctaca
    44581 atgctgtttc ggttaaggtt gccctccata atcaggctat ctatctcctc cttcaaaaag
    44641 gtgttcagcc tgagaaaatt gtgattgatg cctttaccag tgctaaaaat tatgacaagt
    44701 acttggcaca agagaccaat cgtttcagca atcctatcag cttagaagaa aaggctgagg
    44761 gcaaatactt ggctgtcgca gtttcttctg tcattgcgcg tgatctcttt ctggaaaatc
    44821 ttgaaaattt gggacgagaa ctgggttatc agcttccaag tggagctgga acggcttctg
    44881 acaaggtggc tagccagatt ttgcaagcct atggtatgca gggactcaac ttctgcgcca
    44941 aattgcactt taaaaatact gaaaaagcga aaaacgctta gaaaggtaag ttatgaattt
    45001 atttaaaaat ttcttaaaag agtggggatt attcctcctg attctgtcat tactagcttt
    45061 gagccgtatc tttttttgga gcaatgttcg cgtagaagga cattccatgg atccgaccct
    45121 agcggatggt gaaatcctct ttgttgttaa gcacctccct attgaccgtt ttgatatcgt
    45181 ggtggcccat gaggaagatg gcaataaaga cattgtcaaa cgtgtcatcg gaatgcctgg
    45241 cgataccatc cgttacgaaa atgataaact ttacatcaat gacaaagaaa cggacgagcc
    45301 ttatctagca gactatatca aacgcttcaa ggatgacaaa ctccaaagca cttactcagg
    45361 caagggcttt gaaggaaata aaggaacttt ctttagaagt atcgctcaaa aagcccaagc
    45421 cttcacagtt gatgtcaact acaacaccaa ctttagcttt actgttccag aaggagaata
    45481 ccttctcctc ggagatgacc gcttggtttc gagcgacagc cgccacgtgg gtaccttcaa
    45541 agcaaaagat atcacagggg aagctaaatt ccgcttctgg ccaatcaccc gtatcggaac
    45601 attttaagag acctaagagg ccgagaatca ccaatctcag cctcttcttc tatcgtgaga
    45661 agtgattgtt tattgacaaa tactcaatga aaatcaaaga acaaactagg aagctagccg
    45721 taggctgctt aaaacagtgt tttgaggttg tggatagaac tgacgaagtc agctcaaaat
    45781 actgttttga ggttgcagat ggaagctgac gtggtttgaa gatattttcg aagagtataa
    45841 aataaaaaca atcccaactc tcacctattc atgcaaagga attttatgga agtttatttt
    45901 tcaggaacca ttgaacggat tatttttgaa aatcccagca atttttatcg catcctcctc
    45961 ctagaaatcg acgatacgga cgcagaggat tttgatgatt ttgaaatcat tgtcacagga
    46021 accatggctg atgtaattga gggcgaagac tatacttttt gggggcaaat tgtccagcac
    46081 tccaagtatg gagaacaact gcaaatcagt cgttatgatc gcgcaaaacc aactagtaag
    46141 ggcttggtca agtacttttc aagtagccat ttcaagggga ttggtctcaa gacagctcag
    46201 aaaatcgtgg atacctatgg cgaaaatacc attgacgaaa ttttgcaaca cccagaaaag
    46261 ttagaaggca tcgcaggact ctctgccaaa aatcgcgagg ctttcgtctc cactctccgt
    46321 ctcaactacg gaacggagat ggttttgtcc aaactagcca actacggcat tcccaacaaa
    46381 ctagcctttc agattcaaga cttttacaag gaagaaaccc ttgatgtggt tgaaaattat
    46441 ccctaccagc tggttgagga tatcaagggt ttgggcttta ccattgctga ccaactagct
    46501 gaggaactag gcatcgaaag tcaggctcct gaacgcttcc gcgccggtct agttcacagt
    46561 ctttttcagg cctgtatgga aacaggggac acctatgttg aagcacggga tttgctggaa
    46621 caaaccctta ctctccttga gtcttcccgt cccgtggaac tagaccccag tcaagttgcc
    46681 caagagctct cctacctgat cgaagaagac aaggttcagc agattgatac caagatcttt
    46741 gacaacagcc tctttttcgc tgaggaaggc atccgcagtc acttggttcg tatccttgaa
    46801 aaaggagaac agaagagtca tcatttagaa accattcaaa aacatatcac tactatcgag
    46861 caagagctgg gaattgagta tgataacatt caaaaacagg ctatctgtga tgctatccag
    46921 aataaggtct ttatcctgac aggtggacct ggtactggta agacaactgt tatcaatggg
    46981 atcatcgctg tttacgccct gttagaggga cttgacctca ggaagaaaag caatctgccc
    47041 attcttcttg ctgctccaac tggacgagcc gctcgccgca tgaatgaatt gacaggtttg
    47101 cctagcgcga ccatacaccg ccacttggga atgacaggtg acgatgatac cagtcatctg
    47161 gaagattacc tagatgctga ctttatcatc gtggatgaat tctctatggt agatacttgg
    47221 ctgtccaatc aactcttctc caatatctct tctaacagta agatcctcat cgtaggtgac
    47281 agtgatcagc taccttctgt cagtcctgga caggttctag cggatctgct tcatattcct
    47341 ttgattcctc agactcgctt ggaaaaaatt tatcgacaaa gcaaagaatc aaccatcgtc
    47401 accctagcta gtcagattcg acagggcatc ttgccagctg atttcaccca aaaaaaagct
    47461 gaccgttcct actttgaaat tgctagtggc catattcctg ccaccattga aaaaatctta
    47521 ggtgctgccc tcagaaatgg tattcctgcc cgtgatatcc aagttctggc tcctatgtac
    47581 cgagggacgg cagggattga tgctatcaat cagctcatgc aagacctgct caatccccca
    47641 caaaaagatc aactcagttt tgaagctcct cagtgccact atcgtaaggg agacaaggtc
    47701 attcatttgg ttaacgatgc tgaaatcaat gtctttaatg gggatttagg agctatcaca
    47761 gacctgattc ctggtaaata caccgaatcg aaacaagacg agattgtcat tgattttgat
    47821 ggtaatgaag tctcttaccc ccgtaacgaa tggtacaaga ttcgcttggc ctatgccatg
    47881 agtattcata agtctcaggg aagtgagttc ccagttgtca tcctaccgat tactagtgct
    47941 agccgacgta tgctggagcg aaatctcatc tacacagcca ttacacgtgc caaaagcaaa
    48001 ctcatcttac taggcgaatt acaagccttc gaccatgcta tccaacacat cggaactgcc
    48061 cgaaaaacct atctgattga acgcttcagt gatctactgg agaatgttga agaaaagcaa
    48121 caagctgtct ctgaaacagt cacatcaagt gcctctgaac aatcctacat cctaaccgaa
    48181 gaaaactgga accgcatccc agccatgatt gggattacag acacagacct caaagagatt
    48241 tttggaaaat agtgcatcag aaaacccacc aattcaggtg ggttttctgt ttattaagat
    48301 tattttactg ttgctgtgct tgtaatcaat tcaacagctt ttttgattgt gatatcatgt
    48361 ttcaacatgt cagctgaaag caagctttgt acttgagcaa cttccatgtt gtagtctgct
    48421 gccaattgct caacttcttt ttggatttct tcttctgaag catcaaatcc ttcagctttg
    48481 gcaactgctt cgataacaag gttagtctta gtacgtgact cagcttctgc ttggtattgg
    48541 ttgtgaaggt cttcttgagt agttccagtg atttggaagt acatgtcagg gttgatccct
    48601 tgacgttgca agttcccaag gaattcattt actgaacggt gaacttcttc gtggatcatt
    48661 tcttctggaa gttctacgat ttcagcgttt tctacagctg tatcaattgc tgcaccttca
    48721 actgcatctt tgtaagcttc ttctttagca gcagccaatt ctttgcggta tttttctttc
    48781 aagtcagcaa gtgtttcaac ttcttcatca atgtcttttg caagttcatc gtcaagagct
    48841 ggaacttctt tagcttttac ttcgtggata gttgtcacga atttagcttc tttacctgca
    48901 aggtcttctg cttggtagtc ttctgggaat gttacgataa catcaacggt ttcgccagct
    48961 gagtgaccta ccaattggtc ttcgaaacca gggatgaatt gacctgaacc aagtccaagt
    49021 gagaagtttt caccttttcc gccgtcaaat tcaacaccgt cgatagaacc aacgaagtcg
    49081 atcacaacag tgtcgccgtt ttcagcagca gcttccttga taaccaattc agccaggttg
    49141 ttgcgttcgc gttcgatacg ctcttcaaca tcagcgtcag ttacttcttt ttctacatca
    49201 actgatactt caaggttttt gtagtcaccc aattttactt caggttttgt aacgacttca
    49261 gcagcgataa cccagtcttg acctttttcc attgaagtta cgtcaatttt tggttgggca
    49321 accacttcaa gaccagcttc ttttacagct gcttcataag cgtttggcaa aagagcgttc
    49381 ataacgtctt ggtaaagtga ttcttcacca aattttttat cgaagatagg acgtggaagg
    49441 tgacctttac ggaaacctgg aacattaaga gatttcttca ctgacttgaa gacacggtcc
    49501 aattctggtt tgatttggtc ttgagagata gtgaaagtca agacaccacg gtttgtttct
    49561 ttgttttcaa atgatacaga cattctgtca tttctcctta aaatttttta aatacagtct
    49621 attataacat tttctataaa taaaatctag actaatgcag acaattatag acaacaagcc
    49681 tttttcctaa ctaaaacact cataaagtat agacaatttt agactacttt ggatatcttt
    49741 tggttagtca ttttccaaaa ctaatttatc taatttttca gttatatagt atattgaaac
    49801 tagaatagta cacctctact tctaaaacat ttttagaaat cgatttgact gtcctgatcg
    49861 atttgtcctg ttcttgtttc attttactat atagatcgca ttcgaaagaa ttcgttccaa
    49921 aattgcttgg ttcgttcttc tcttggacga ctaaagaatt gatgggcatt atttttttca
    49981 acaattttcc caccgtccat aaaaataaca tgataggcta catctctagc aaaacctatc
    50041 tcataaagct gatcaaaaac tcaatctgag gagaaaatcc aataaggctt tccataataa
    50101 aggacatcct atcaagattt ttgaacaccc gataggctgc ctttttccga ttttgaagac
    50161 tttttgtcca gcttctttta ccttataaat aacaacaaaa atcaaagaca agctagaaag
    50221 attaccgcag ataactcaaa cagtgttttg aggttgcaga taagactgac gaagtcagct
    50281 caaagcactg ctttgaggtt gtagatagaa ctgacgaagt cagctcaaaa tactgttttg
    50341 aggttgcaga tggatgctaa cctgatttga agagattttc gaaaaatatt aaatatactc
    50401 tacaattcgc tcaatcaatt cttggtcgtc taaacctgta acttgtataa caacatcttt
    50461 gactgattgt ttagccaaca attcacctaa tcgaatactt tcttcatcat ttacatcgcg
    50521 atagtcaaag gcatagccaa ctgttttaag taggttttta tatgacaaac tgagttcttt
    50581 caattcacgt atcggccgga tgaatcgttc attatagcct aattttcgga ttggagtacg
    50641 agctacgcga ctaacctcgt ccactatgaa agggttttca aatcgttcta taatgacttt
    50701 gtgataattc tccaattctt ttttatcaaa gttccatttg gcaatcaaga gactccgaat
    50761 ttcagctaat acagattcaa tccgagattt gatattagga ttttgaagag cttccaaaat
    50821 tgtcttggca ccataatgcg caccaatgta agctgaagtt gcatgtccag aattgactga
    50881 aaaaagtttt cgctcaataa agggttctaa atcttcttca taatgcacat cttctagacg
    50941 taaatctgga tttttaagac gcttggtttc cacgacccat tcattaaagg gctcgaccat
    51001 aacaaaaagg gaatcttcgt gactttgtgt tggaacaatc ctgtctactg cagcatttgg
    51061 aaaacctatg tagttatcag caaatgtcaa accttccgga cttaaatatt tcttgacttc
    51121 ttgataaaga aattgagacc cgccaatcat attttcacag gccataacat ccaatgcctg
    51181 tgtatttcct gcaactcggc gagcttcgat tcctttggct agaagttcag cgataaaagg
    51241 gagtatatta ggtccgattg cagtagtaat aatatccgtc ttttgaatcg cttcaatgac
    51301 ttgctcagga tgttctttgc tattaatgcc agccacatta gttacttcta tacgagactg
    51361 tcctttctgt gcaatttcaa tttcatactt gcccttttca tttagagcat gaattatctg
    51421 attattgaca tccacaaaat caatatggaa accattttta aatagaattt cacctataaa
    51481 accacgaccg atattaccgg caccaaaatg aacagaatgt ttcattcaat ttctcctttt
    51541 cctatttgag ggacatatat actagatgac aaatgacgaa attcaattat tcaacagcat
    51601 caaataagcg caatacttcc tcttttgact gagcatctgc tagtttaaga acattatcta
    51661 catctgcaca gaagatagaa attttctgaa taatttctaa gtgttcatta ccaataccag
    51721 caataccaaa aagaaccgtt gccacttgag ggttagatac attcccaaaa tcaacccctc
    51781 tagggacttg aacgactgta ataccagact tgagtacatc cttttttgct gcatctgttc
    51841 catgcggtat ggcgataaag ttacccatgt aaacagatag ctctttatct cgctcaatca
    51901 tggcttcaat atagtcttca ttaacatatc caccctcata aagaacttgc ccacaataac
    51961 aaatagcttc ctccttgtta gaaaattgtt tattaagctt aatcaaatgt ttttcaagtt
    52021 tcatattagt tctccaattt cttaattttt tcgttaaaaa tagtatttag catctgataa
    52081 ataatggatt gatttcccgt cttgtaaatc tctgtataaa gatgattttc aataatcgac
    52141 tgactgatag ctgtcattaa atctctcgct tcctcgctag cttctttaga cattagcatt
    52201 agcagacacc ttttgacctc ttctttctct cgtttcattg acaatgcgga gataggtagt
    52261 ttgagttcaa acatagtaaa actatttgtt gttactttgc tagactgact atgtaaaagc
    52321 accagaccag tattaggaat agccatagga ctattctgga agtgagataa caattttctt
    52381 gttaggtaat ctctgtcact cacattcttc tgatattgga tgatttgttc taccgtgtgc
    52441 tcaaatgatt gattattctc caattgaacc aactcgaatt gactcaaaag ctgactacta
    52501 gatattaaat aatcttgcaa gtcataactt ttctctggag cgatagcatc acgcgcgaca
    52561 attgtacgat gtgcctgtac atactgaagt cgttcctgta attcaagcaa ttctttgacg
    52621 gttggaaaac tagaaattac atcgatttcc tgattagtca gcggcttggt agataaaata
    52681 taatcatact gactgagatc aatactgtgg taatctacta gagactgaat atctatcaac
    52741 tctacaaaag gagcaacact cttaatttta ctgactaata aatctctagt gacccgacgt
    52801 tcatccgtta aaagcaaaac acggactgga taaatctctg gactacggcc taagctagag
    52861 ataaaatgta gggcaatcat gccatactca tactctgtat gaagatattt cggaaaaata
    52921 tcattcacta aaagactgat gactgtataa agaaatttat tcctttcaac taaaatctgg
    52981 acagattctg gcaaattttc accctgaaaa aggataggga cgcctaaact gagccgaata
    53041 tgatggaaaa gaaaattgaa taaaaccttg tccttaaaaa agtcaatctt ggtatacatg
    53101 gaaaccgtat caatcagatt tgaaatattg tagaaaaatt caccatcaaa tttctccgta
    53161 aagagcggat tgtcctgacg tttaatgatt aattcatcca agatgctcgc aaaatagata
    53221 atttcctgaa tactataaaa ttgtgcagtc tgcttagagt aagcttgaaa aattttttga
    53281 gaaatttcca aagcctgctt actagtatta ggtgaatttt caatgttttg ctcctgacct
    53341 ataagagata acaagatcgc aaaaaacatc ttcatcctag catccatatc tggaaaacct
    53401 gacagttgct tattaacaat ctgactggcc agcctagttc tatctgcttc taaaatatca
    53461 aagctcccaa aattaccggt tgaaaaatct gctactgaga tacagtttgt cagtaaaata
    53521 gccaaaaatc ttctcttacc aactgaatca ccagaaatcc gataaccttt ttgtcgttca
    53581 attttcagat caaagtctaa aagacgctta tcaatatctg aaatatcctg aataatagtt
    53641 acattactga ctttcgtgca ctcttgcaat gcttcattgg tgacaaaacc actctcagtc
    53701 agaaggcgat aggtaatcaa ctcttgtctt tcttggggac tatactcaac taacacttca
    53761 agttctgtcg gcaaatcatc caactctcca gtcaaaatat agtatttccc atgctttgtt
    53821 atttcgattc catattgctc catgctatct gtcaaatctg ataaagttcg ataaattgtt
    53881 ctagatgaaa cctgtaagat ttcagtcata tcttgcattg aaagcttccc tacatgtagg
    53941 aaagccttca ataattgttc ttctcgtttg gttaatagca ttcgtaattt agaaacctct
    54001 agttctattt gtacattcta gcagccattt tgtcatattc tggtgttgtt actaaactat
    54061 ccacaataag aaattgagaa ttcggtgctg cttgctgcac ttctgcctgt aaagaaatag
    54121 ttgttacaat cattatgttt ttagaattaa attcacctaa ttctgaaatt ttggcagtag
    54181 aaactggaat acgaatattc ttgtttctaa agatagcccg aatcgtttca cagcccatag
    54241 ttgcagttcc ctgtgcttta ccataagcaa ctactacagc atcaatatgg ttgaggtcaa
    54301 tttcctgact atctactggt gctgaagttg gtatatctcc ttcaatttct gctattggag
    54361 aagctcctgt taatgaagct acaatttcat cataacgagg ggacgctaag aaattatcaa
    54421 cagaaacatg aatagcactt ggactcttgt ctttagctct tggtgtcagt tcttcctgag
    54481 taacaattaa tgtttttggt gtatcaagca aatttgagat tgcctgatta gatactggaa
    54541 tctctagacc tgctttttta accttatctc gaagaatact agctcccata gcagagcttc
    54601 ccataccagc atcgcaggcg aaaatgattt tttccactga gtctgtcgaa acaactgcat
    54661 caacagaagt tgatactaac tgacctttag actgagcctt agctgcttgg gtagccgcct
    54721 gagcagcttc gagcgaatcc tcagttgact tgtctgcatg aagaataagg gctgctacaa
    54781 ggaaagaaac aactgctgcc actaaaacac ctaaaagaac atttagatgg ggccaaacac
    54841 cttttggcgc cgtagccata atcgcaataa tagaacctgg tgaagctgga gatttaagac
    54901 cagcgtctaa gagttgaaaa gtaaaagttc cagagatacc tcctgccata gcagctaaaa
    54961 atagagtagg cttcatcata acataaggaa agtaaatttc atgaatccct ccgaagaaat
    55021 gaataaccat tgccccccaa gaagaagatt tagcagaacc tttaccgaat acagcataag
    55081 ctaatagaat tcccaggcct ggtccaggat tagcttccaa taggaagaga attgacttac
    55141 cagcttgagc tacctgttct actcccagag gagtaaaaat gccatgattg agggcattat
    55201 tgaggaaaag gactttagcc ggttcgatga taatattagc cataggaagg aggcgagcat
    55261 tgacaatagc ctcaacacca ttcccaacag ctccagtaag agtcgatacg actggaccga
    55321 ttgcgtagaa agccaaaagc aataatgcaa aaccaacgag accagctgag aagttattaa
    55381 ctaacatttc aaatccggga cgaatttttt cttggaactt ctcatcaaat ttcttgatag
    55441 tccatcctcc cagtgggccc attaccatag ctccgataaa cataggaaca ctagaacctg
    55501 tgattgcgcc aacagtagca atagatccta caacggcacc acgttggcca tggatcatat
    55561 atccacctgt gtaaccaatc aggattggca ataaatacgt taacatagga ccaacaacag
    55621 tagctaactg ttcatttggc agatagccat cagcgataaa gagggcagtc aatactcccc
    55681 aagcaataaa tgctccaata ttgggcataa ccatatttga aagcgatgtc cctagttttt
    55741 gaaccctgac tttcaatgat actttttctt ccattagatc atcctccttt tcttaaaact
    55801 agtatataca aagttaaaaa cctttaaaac taaagttttg tcacagattt tgtgtcaaaa
    55861 cattactttt gatgaggctg ggcaaaaagg cttaaaaatt ataaaacgca tcatatcagg
    55921 tgtacatgaa ctacacccca aaagttagac agaaaaaatc taacttttgg ggtgttttta
    55981 ttatgaaatt aacttatgat gataaagtcc agatctatga acttagaaaa caaggatata
    56041 gcttagagaa gctttcaaat aaatttggga taaacaattc taatattagg tacatgatta
    56101 aattgattga tcgttacgga atagagttca tcaaaaaagg aaaaaatcgt tactattctc
    56161 ctgatttaaa acaagaaatg attaataaag tctgacatga aggctggact aaagatagag
    56221 tttctcttga atacggcctc ccaagtcgta cgatacttct taactggcta gcacaataca
    56281 ggaaaaacgg gtatactatt gttgagaaaa caagagggag agtacctaaa atgagacgta
    56341 agccaaaaaa gagacctgaa gagaggacag aattagaacg tcttcaagca gaaaatgagt
    56401 acctgagagc ggagaaggcc atcctaaaaa agttaagaga actccgattg aaggaggaaa
    56461 aagagaaaga agaaagacag aaattgttta agaattaatg actgagtttt cgttagctct
    56521 tcttctaaaa tccattaaac tagctcgttg gacctactac tatcacttga aacagctaga
    56581 taaaccagat aaggaccaag agcttaaagc tgaaattcaa tccattttta tctaacacaa
    56641 gggaaattat gcttatcgtc ggatttattt agaactaaga aatcgtggtt atctggtaaa
    56701 tcataaaaga gttcaaggct tgat
//
LOCUS       DAVHTH010000007        55441 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.007, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000007 DAVHTH010000000
VERSION     DAVHTH010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 55441)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 55441)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..55441
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.007"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            complement(68..1003)
                     /locus_tag="VVR63_000423"
     CDS             complement(68..1003)
                     /locus_tag="VVR63_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     synthetase/biotin operon repressor"
                     /protein_id="HEU6128477.1"
                     /translation="MKSYQAVYQILSKETDYISGEKIAEKLSLSRTSIWKAIKRLEQE
                     GIEIDSIKNRGYKLMNGDLILPEILEENLPIKVSFKPETKSTQLDAKEAIDLGHEANT
                     LYLASYQTAGRGRFQRSFYSPQGGIYMTLHLKPNLPYDKLPSYTLLVAGAVYKAIKNL
                     TLIDVDIKWVNDIYLNNHKIGGILTEAMTSVETGLVTDIIIGVGINFTIKDFPQELKE
                     KAASLFKATAPITRNELIIEIWRAFFETPAEELLYLYKKQSFILGKEVTFTLQQKDYK
                     GLAKDISENGKLLVQCDNGKEIWLNSGEISLNSWK"
     gene            complement(1000..1860)
                     /locus_tag="VVR63_000424"
     CDS             complement(1000..1860)
                     /locus_tag="VVR63_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000959966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEU6128478.1"
                     /translation="MLVFSEYQTGTIDLALSFYGYEECTPNYSFGPAIRDTYVLHYIT
                     KGQGKFHYKGKIVDLKEGDFFLLKPEELTFYQADSKEPWAYYWLGITGGKAPDYFALS
                     QISDQSYLIQSETCHTQTTAKLISDIVRFAQITKSSELAQLHIMGQLHELMFHLGTIA
                     PNQKKKNISSTHQLYLECKRLIDSHYPQSLTIQDLAKELSVHRSYLSSVFKEFNTLSP
                     KEYLLYVRMHRARQLLENTQESIKVIAYSVGFSDPLHFSKAYKQYFNQTPSHTRKEYS
                     QYQLVRKATL"
     gene            1968..4130
                     /locus_tag="VVR63_000425"
     CDS             1968..4130
                     /locus_tag="VVR63_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000538915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HEU6128479.1"
                     /translation="MGVRIENNLFYVESKNLSLIIENRNGYLLLKHLGKTIKNYKGSN
                     SVYERDHAFSGNPTATNRTFSLDTQRQIFGQHGLGDFRKPTIQVQHNVTEVTDFRFVE
                     AKILKGQNGPQGLPSPHSMDDTETLVLMLEDSKAQLSLTLYYTTFNNDATIASYSKLD
                     NNSNQEVVIHKDFSFMADFPAADYEIATLQGAYAREKTVRRQQVEQGIFSISSNRGAS
                     GHAQTPALLLCEQGVTEDAGNVFAIQLMYSGNFEAFVQKNQLNEVRVAIGINPENFSW
                     KLAPEEYFETPVALVTHSDQGLTGISHESQNFVLKHIMLSEFSKKERPILINNWEATY
                     FDFQREKLLELADEAKKVGIELFVLDDGWFGNRFDDNRALGDWVVNEEKLGGSLESLI
                     SAIHERGLQFGLWLEPEMISVDSDLYRQHPDWAIQVPDYEHTYSRNQLVLNLANPQVV
                     EYLKSVLDQLLSYHEIDYIKWDMNRNITKLGNGLTYLETQMQSHQYMLGLYELVSYLT
                     EKHSHILFESCSGGGGRNDLGMIRYFPQVWASDNTDAIARLPIQYGSSYLYPTISMGA
                     HVSAVPNHQMGRMTPLETRGHVAMMGNLGYELDLTNLSDEEKATIANQVNLYKELRPV
                     VQLGQQYRLINPDTASNEAAVQFNYGNQTIVTYVRVLSVVETMETTLKLKDLDEEGLY
                     KLQENGEVYSGAELMYAGLTVILSQGDFLSRQYIFRKL"
     gene            4222..5481
                     /locus_tag="VVR63_000426"
     CDS             4222..5481
                     /locus_tag="VVR63_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEU6128480.1"
                     /translation="MEWYKKIGLLATTGLALVGLGACSNYGKSADGTVTIEYFNQKKE
                     MTKTLEEITRDFEKENPKIKVKVVNVPNAGEVLKTRVLAGDVPDVVNIYPQSIELQEW
                     AKAGVFEDLSNKDYLKRVKNGYAEKYAVNEKVYNVPFTANAYGIYYNKDKFEELGLKV
                     PETWDEFEQLVKDIVAKGQTPFGIAGADAWTLNGYNQLAFATATGGGKEANQYLRYSQ
                     PNAIKLSDPIMKDDIKVMDILRINGSKQKNWEGAGYTDVIGAFARGDVLMTPNGSWAI
                     TAINEQKPNFKIGTFMIPGKEKGQSLTVGAGDLAWSISATTKHPKEANAFVEYMTCPE
                     VMQKYHDVDGSPTAIEGVKQAGEDSPLAGMTEYAFTGRHLVWLQQYWTSEADFHTLTM
                     NYVLTGDKQGMVNDLNAFFNPMKADVD"
     gene            5495..6361
                     /locus_tag="VVR63_000427"
     CDS             5495..6361
                     /locus_tag="VVR63_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU6128481.1"
                     /translation="MKKVLQKYWAWAFVVIPLLLQAIFFYVPMFQGAFYSFTNWTGLT
                     YNYKFVGLNNFKLLFMDPKFMNAIGFTAIITIAMVVGEIALGIFIARVLNSKIKGQTF
                     FRAWFFFPAVLSGLTVALIFKQVFNYGLPAIGNALHIEFLQTSLLGTKWGAIFAAVFV
                     LLWQGVAMPIIIFLAGLQSIPTEITEAARIDGATSKQVFWNIELPYLLPSVSIVFILA
                     LKGGLTAFDQVFAMTGGGPNNATTSLGLLVYNYAFKNNQFGYANAIAVILFFLIVVIS
                     IIQLRVSKKFEI"
     gene            6375..7208
                     /locus_tag="VVR63_000428"
     CDS             6375..7208
                     /locus_tag="VVR63_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU6128482.1"
                     /translation="MKQDERKALIGKYILLILGSVLILVPLLATLFSSFKSTKDIVDN
                     FFGFPTNFTWDNFSRLLADGIGGYYWNSVVITVLSLLAVMIFIPMAAYSIARNMSKRK
                     AFTIMYTLLILGIFVPFQVIMIPITVMMSKLGLANTFGLILLYLTYAIPQTLFLYVGY
                     IKISIPESLDEAAEIDGANQFTTYFRIIFPMMKPMHATTMIINALWFWNDFMLPLLVL
                     NRDSKMWTLPLFQYNYAGQYFNDYGPSFASYVVGIISITIVYLFFQRHIISGMSNGAV
                     K"
     gene            7519..8961
                     /gene="gtfA"
                     /locus_tag="VVR63_000429"
     CDS             7519..8961
                     /gene="gtfA"
                     /locus_tag="VVR63_000429"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HEU6128483.1"
                     /translation="MPIQNKTMLITYSDSLGNNLKDLYDNLEEHFGDAIGGVHLLPFF
                     PSTGDRGFAPVDYDEVDSAFGDWEDVKRLGERYYLMFDFMINHISRQSKYYKDYQEKH
                     EASEFKDLFLNWDKFWPENRPTQSDVDLIYKRKDRAPKQEIVFEDGSVEHLWNTFGEE
                     QIDLDVTKEVTMEFIRKTIQHLASNGCDLIRLDAFAYAVKKLDTNDFFVEPDIWDLLD
                     KVRDIAAEYGTELLPEIHEHYSIQFKIADHDYYVYDFALPMVTLYTLYSSRTERLAKW
                     LKMSPMKQFTTLDTHDGIGVVDVKDILTDEEIDYASNELYKVGANVKRKYSSAEYNNL
                     DIYQINSTYYSALGDDDVKYFLARLIQAFAPGIPQVYYVGLLAGKNDLKLLEETKEGR
                     NINRHYYSNEEIAKEVQRSVVKALLNLFSFRNRSEAFDLEGTIEIETPTVHSIVIKRQ
                     NKDKSVTAVAEIDLQNQTYRVIENGVEVTF"
     gene            9099..10292
                     /locus_tag="VVR63_000430"
     CDS             9099..10292
                     /locus_tag="VVR63_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008293041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HEU6128484.1"
                     /translation="MKSIGFIEKLKGLSSKELILLGIILSIFLPFYLFVVVLCLYIIS
                     LIFTGDMKSILQKMGEHPMLLLFLSYSTVISILAQNWMGLVASVGMFLFTIFFLHYQS
                     ILSHKFFRLILQFVLFGSVLSAAFASLEHFQIVKKFNYAFLSPNMQVWHQNRAEVTFF
                     NPNYYGIICCFCIMIAFYLFTTTKLNWLKVFCVIAGFVNLFGLNFTQNRTAFPAIIAG
                     AIIYLFTTIKNWKAFWLSIGVFAIGLSFLFSSDLGVRMGTLDSSMEERISIWDAGMAL
                     FKQNPFWGEGPLTYMHSYPRIHAPYHEHAHSLYIDTILSYGIVGTILLVLSSVAPVRL
                     MMDMSQESGKRPIIGLYLSFLTVVAVHGIFDLALFWIQSGFIFLLVMCSIPLEHRMLV
                     SDMTD"
     gene            10979..12958
                     /locus_tag="VVR63_000431"
     CDS             10979..12958
                     /locus_tag="VVR63_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000742236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU6128485.1"
                     /translation="MKKNRVFATAGLVLLAAGVLAACSSSKSSDSSAPKAYGYVYTAD
                     PETLDYLISSKNSTTVVTSNGIDGLFTNDNYGNLAPAVAEDWEVSKDGLTYTYKIRKG
                     VKWFTSDGEEYAEVTAKDFVNGLKHAADKKSEAMYLAENSVKGLADYLSGTSTDFSTV
                     GVKAVDDYTLQYTLNQPEPFWNSKLTYSIFWPLNEEFETSKGSDFAKPTDPTSLLYNG
                     PFLLKGLTAKSSVEFVKNEQYWDKENVHLDTINLAYYDGSDQESLERNFTSGAYSYAR
                     LYPTSSNYSKVAEEYKDNIYYTQSGSGIAGLGVNIDRQSYNYTSKTTDSEKVATKKAL
                     LNKDFRQALNFALDRSAYSAQINGKDGAALAVRNLFVKPDFVSAGEKTFGDLVAAQLP
                     AYGDEWKGVNLADGQDGLFNADKAKAEFAKAKKALEADGVQFPIHLDVPVDQASKNYI
                     SRIQSFKQSVETVLGVENVVVDIQQMTSDEFLNITYYAANASSEDWDVSGGVSWGPDY
                     QDPSTYLDILKTTSSETTKTYLGFDNPNSPSVVQVGLKEYDKLVDEAARETSDLNVRY
                     EKYAAAQAWLTDSSLFIPAMASSGAAPVLSRIVPFTGASAQTGSKGSDVYFKYLKLQD
                     KVVTKEEYEKAREKWLKEKAESNEKAQKELASHVK"
     gene            13025..14521
                     /locus_tag="VVR63_000432"
     CDS             13025..14521
                     /locus_tag="VVR63_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6128486.1"
                     /translation="MKKYIFMRVLRSLVSIFLVTTLTYTIIYTLVPRKLIFKQDPNYN
                     KIATTADKRDNYENTVFERMGYIEYYDTKELQEKASSMDSSVTVEANATNKAIYEKYI
                     NQLGHGWTLGEFTESGQFYATREIPIFERVFHFYANLIDIDHTNKIQDPENPDLKRYL
                     RFENDPAIGWSLVGSGTKHKYLLYFNSQFPFVHQNFVNLNLGDSYPTYANTPVLQVIT
                     QGQGQTKTAQVQFPTGKKTSSVNIYSRTYKSPSQADSREVASYGKDDPYTATESNYQY
                     PSMIVSSAITGLIGLVLAYALAVPLGSAMARFKNTWIDSLSTGTLTFLLALPTIALVY
                     IVRLIGSSIALPDSFPILGAGDWRSYVLPAVILGLLGAPVTAIWIRRYMIDLQSQDFV
                     RFARAKGLSEKEISNKHIFKNAMVPLVSGIPGAIIGVIGGATLTETVFAFPGMGKMLI
                     DSVKASNNSMVVGLVFIFTCISIFSRLLGDIWMTIIDPRIKLTEKGGK"
     gene            14521..15447
                     /locus_tag="VVR63_000433"
     CDS             14521..15447
                     /locus_tag="VVR63_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6128487.1"
                     /translation="MSTIDKEKFQFVKRDDFASETIDAPAYSYWKSVFKQFMKKKSTV
                     VMLGILVAIILISFIYPMFSKFDFNDVSKVNDFSVRYIKPNAEHWFGTDSNGKSLFDG
                     VWFGARNSILISVIATVINLVIGVFVGGIWGISKSVDRVMMEVYNVISNIPPLLIVIV
                     LTYSIGAGFWNLIFAMSVTTWIGIAFMIRVQILRYRDLEYNLASRTLGTPTLKIVAKN
                     IMPQLVSVIVTTMTQMLPSFISYEAFLSFFGLGLPITVPSLGRLISDYSQNVTTNAYL
                     FWIPLTTLVLVSLSLFVVGQNLADASDPRTHR"
     gene            15456..16523
                     /locus_tag="VVR63_000434"
     CDS             15456..16523
                     /locus_tag="VVR63_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6128488.1"
                     /translation="MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALV
                     GESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDLTALSSHKDWEQIRGAKIATIFQ
                     DPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
                     SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITH
                     DLGVVASIADKVAVMYAGEIVEYGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSI
                     PGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAKTWLLHEDAPKVEKP
                     AVIANLHDKIREKMGFAHLAD"
     gene            16534..17460
                     /locus_tag="VVR63_000435"
     CDS             16534..17460
                     /locus_tag="VVR63_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6128489.1"
                     /translation="MSEKLVEIKDLEISFGEGSKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNDTSNGDIIFDGQKINGKKSREQAAELIRRIQMIFQDPAASLNE
                     RATVDYIISEGLYNHRLFKDEEERKEKVQSIIREVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMQPDFVIADEPISALDVSVRAQVLNLLKKFQKELGLTYLFIAHDLSVVRFIS
                     DRIAVIYKGVIVEVAETEELFNNPIHPYTQALLSAVPIPDPILERKKVLKVYDPSQHD
                     YETDKPSMVEIRPGHYVWANQAELARYQKGLN"
     gene            17951..18466
                     /locus_tag="VVR63_000436"
     CDS             17951..18466
                     /locus_tag="VVR63_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000512060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU6128490.1"
                     /translation="MGILLTSLISLHQLKADKKRDVFRIGISQFITHQSLDATREGFV
                     DELAKQGYVEGENIEIDLQNAQGEQRNLKTISQQLAESSDVVLAIARPSAQSLANTTQ
                     TTPVIFSAVTDPVSAKLVESREHPGGNVTGTSDQSSDAISTQINLIKKVLPKAKTIGI
                     LYTQSEPNSVV"
     gene            18488..18871
                     /locus_tag="VVR63_000437"
                     /pseudo
     CDS             18488..18871
                     /locus_tag="VVR63_000437"
                     /inference="COORDINATES: protein motif:HMM:NF016292.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
     gene            18902..19779
                     /locus_tag="VVR63_000438"
                     /pseudo
     CDS             18902..19779
                     /locus_tag="VVR63_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001012086.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
     gene            19792..20595
                     /locus_tag="VVR63_000439"
     CDS             19792..20595
                     /locus_tag="VVR63_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000157668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU6128491.1"
                     /translation="MASLLTLENIHKTFEAGTVNENHVLKGLDLEVEEGDFIYVIGGN
                     GAGKSTLMNILAGNLSVDEGDLLLAGKSIKNLSVRKRAKDIARVFQYPKMGTASRLTI
                     EENMAIALRRGQKRGLGWGVKEKDRIQFQEALKELNIGLENRLKVDTQYLSGGQRQAL
                     TLVMAALVKPKLLLLDEHTAALDPKTSQMVMDLTQKIVEHHQWTTLMITHDMNHAIEY
                     GNRLIMLYQGKIVVDVKGEEKKHLTVEDLMHLFQKNSGQSLVSDELVLG"
     gene            complement(20628..21338)
                     /gene="treR"
                     /locus_tag="VVR63_000440"
     CDS             complement(20628..21338)
                     /gene="treR"
                     /locus_tag="VVR63_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HEU6128492.1"
                     /translation="MKKYQQLFKQIQETIQNETYAVGDFLPSEHDLMEQYQVSRDTVR
                     KALSLLQEEGLIKKIRGQGSQVVKEETVNFPVSNLTSYQELVKELGLRSKTNVVSLDK
                     IIIDKKSSLITGFPEFRMVWKVVRQRVVDDLVSVLDTDYLDMELIPNLTRQIAEQSIY
                     SYIENGLKLLIDYAQKEITIDHSSDRDKILMDIGKDPYVVSIKSKVYLQDGRQFQFTE
                     SRHKLEKFRFVDFAKRKK"
     gene            21523..23490
                     /gene="treP"
                     /locus_tag="VVR63_000441"
     CDS             21523..23490
                     /gene="treP"
                     /locus_tag="VVR63_000441"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HEU6128493.1"
                     /translation="MGKFEQEAKDLLQAIGGKENVTAVTHCATRMRFVLGDDKKANVK
                     AIESIPAVKGTFTNAGQFQVIIGNDVPIFYNDFTAVSGIEGVSKEAAKSAAKSNQNVV
                     QRVMTTLAEIFTPIIPALIVGGLILGFRNVLEGVHWSMLDGKTITESSQFWAGVNHFL
                     WLPGEAIFQFLPVGITWSVSRKMGTSQILGIVLGICLVSPQLLNAYAVASTPAADIAA
                     NWVWNFGYFTVNRIGYQAQVIPALLAGLSLSYLEIFWRKHIPEVISMIFVPFLSLIPA
                     LILAHTVLGPIGWTIGQGLSSVVLAGLTGPVKGLFGAIFGALYAPFVITGLHHMTNAI
                     DTQLIADAGGTALWPMIALSNIAQGSAVFAYYFMHRHDEREAQVSLPATISAYLGVTE
                     PALFGVNVKYIYPFVAGMTGSALAGMLSVTFNVTAASIGIGGLPGILSIQPQYMLPFA
                     GTMLVAIVVPMLLTFFFRKAGLFTKIEGDTNLQAEFVAQEEAEFVNHEPVELTSVEII
                     SPLTGQVKELSQATDPVFASGVMGQGLVIEPSQGELTSPVNGTVTVLFPTKHAIGIVS
                     DEGVELLIHIGMDTVGLDGKGFESLVVQGDHVIVGQQLIRFDMDVIKAAGLVTETPVI
                     ITNQDAYTATITGTYPTTIQAGASLMVATRI"
     gene            23668..25293
                     /gene="treC"
                     /locus_tag="VVR63_000442"
     CDS             23668..25293
                     /gene="treC"
                     /locus_tag="VVR63_000442"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HEU6128494.1"
                     /translation="MTLDKGKVVYQIYPKSYKDTTENGIGDFRGIIEKIPYLAKLGVD
                     MVWLNPFYPSPQRDNGYDISDYMAVDPLFGDMADFEEMVCIGKEHKIDFMLDMVLNHC
                     STEHEWFQKALAGDKYYQDFFFIQDQPTDWQSKFGGSAWAPFGDTGKYYLHLFDETQA
                     DLNWRNPNVRKELFKVVNFWRDKGVKGFRFDVINLIGKDEVSVDCPENEGKPAYTDKP
                     IVHNYLRMMNQATFGSDDSFMTVGEMSSTTMENCVLYSSPDRQELSMTFNFHHLKVDY
                     KDGQKWTLAPFDFEELKSLYHSWGKEMSDKDGWSALFWNNHDQPRALNRFVDIQNFRK
                     EGATMLAASIHLSRGTPYIYMGEEIGMIDPDYDSMADYVDVESLNAYQMLLEEGKSQQ
                     EAFQIIQAKSRDNSRIPMQWDASENAGFSTGTPWLKAGKSYKYINVENEIQGPIFTFY
                     QDLIRLRKEMPIISEGSYKPAFEDSKQVYAFERQFEDQKLLVLNNFYAKEVEIDLPAV
                     YQNGQILISNYEDAEVSEKILLKPYQTLAIYVN"
     gene            25549..25797
                     /locus_tag="VVR63_000443"
     CDS             25549..25797
                     /locus_tag="VVR63_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HEU6128495.1"
                     /translation="MDLLLAIVLIVLAFLGGALGGMYLVRKQIEKEFADNPRLNAEAV
                     RTLLSANGQKPSEAKVQQVYHQIIRQQKAALANNKKKK"
     gene            26004..26798
                     /gene="racE"
                     /locus_tag="VVR63_000444"
     CDS             26004..26798
                     /gene="racE"
                     /locus_tag="VVR63_000444"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HEU6128496.1"
                     /translation="MDNRPIGFLDSGVGGLTVVRELMRQLPHEEIVYIGDSARAPYGP
                     RPAEQIREYTWQLVNFLLTKDVKMIVIACNTATAVVWEKIKAQLDIPVLGVILPGASA
                     AIKSSQGGKIGVIGTPMTVQSDIYRQKIHDLDPDLQVESLACPKFAPLVESGALSTSV
                     TKKVVYETLRPLVGKVDSLILGCTHYPLLRPIIQNVMGPKVQLIDSGAECVRDISVLL
                     NYFEINRGRDAGPLHHRFYTTASSQSFAQIGEEWLEKEIHVEHVEL"
     gene            26795..27766
                     /locus_tag="VVR63_000445"
     CDS             26795..27766
                     /locus_tag="VVR63_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000182414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HEU6128497.1"
                     /translation="MTNKIYEYKDDQDWYVGSYSIFGGVNSLSDYQTDFPLFEFSKIF
                     GDEEYGFPLSVTVLRYGSTYRLFSFVVDMLNQEMGRNLEVIQRHGALLLVENGQLLYV
                     ELPKEGVNVHDFFETSKVRETLLIATRNEGKTKEFRAIFDKLGYDVENLNDYPDLPEV
                     AETGMTFEENARLKAETISQLTGKMVLADDSGLKVDVLGGLPGVWSARFAGVGATDRE
                     NNAKLLHELAMVFELKDRSAQFHTTLVVASPNKESLVVEADWSGYINFEPKGENGFGY
                     DPLFLVGETGESSAELTLEEKNSQSHRALAVKKLLEVFPSWQSKPSL"
     gene            27742..28263
                     /locus_tag="VVR63_000446"
     CDS             27742..28263
                     /locus_tag="VVR63_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEU6128498.1"
                     /translation="MAKQTIIVMSDSHGDSLIVEEVRDRYVGKVDAVFHNGDSELRPD
                     SPLWEGIRVVKGNMDFYAGYPERLVTELGSTKIIQTHGHLFDINFNFQKLDYWAQEEE
                     AAICLYGHLHVPSAWLEGKILFLNPGSISQPRGTIRECLYARVEIDDSYFKVDFLTRD
                     HEVYPGLSKEFSR"
     gene            28260..28721
                     /locus_tag="VVR63_000447"
     CDS             28260..28721
                     /locus_tag="VVR63_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEU6128499.1"
                     /translation="MIAKEFETFLLGQEETFLTPAKNLAVLIDTHNADHATLLLSQMT
                     YTRVPVVTDEKQFVGTIGLRDIMAYQMEHDLSQEIMADTDIVHMTKTDVAVVSPDFTI
                     TEVLHKLVDESFLPVVDAEGIFQGIITRKSILKAVNALLHDFSKEYEIRCQ"
     gene            28712..29452
                     /gene="xerD"
                     /locus_tag="VVR63_000448"
     CDS             28712..29452
                     /gene="xerD"
                     /locus_tag="VVR63_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HEU6128500.1"
                     /translation="MPMRDRISAFLEEKQGLSVNSKQSYKYDLEQFLDMVGERISETS
                     LKIYQAQLANLKISAQKRKISACNQFLYFLYQKGEVDSFYRLELAKQAEKKTEKPEIL
                     YLDSFWQESDHPEGRLLALLILEMGLLPSEILAIKVADINLDFQVLRISKASQQRIVT
                     IPTALLSELEPLMGQTYLFERGEKPYSRQWAFRQLESFVKEKGFPSLSAQVLREQFIL
                     RQIENKVDLYEIAKKLGLKTVLTLEKYR"
     gene            29452..30180
                     /locus_tag="VVR63_000449"
     CDS             29452..30180
                     /locus_tag="VVR63_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000351912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HEU6128501.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSKYQMDIYDVPITEVIEQYLAYVST
                     LQAMRLEVTGEYMVMASQLMLIKSRKLLPKVAEVTDLGDDLEQDLLSQIEEYRKFKLL
                     GEHLEAKHQERAQYYSKAPTELIYEDAELVHDKTTIDLFLAFSNILAKKKEEFAQNHT
                     TILRDEYKIEDMMIIVKESLIGRDQLRLQDLFKEAQNVQEVITLFLATLELIKTQELI
                     LVQEESFGDIYLMEKKEESQVPQS"
     gene            30199..30768
                     /locus_tag="VVR63_000450"
     CDS             30199..30768
                     /locus_tag="VVR63_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein B"
                     /protein_id="HEU6128502.1"
                     /translation="MSTLAKIEALLFVAGEDGIRVRQLAELLSLPPTGIQQSLGKLAQ
                     KYEKDPDSSLALIETSGAYRLVTKPQFAEILKEYSKAPINQSLSRAALETLSIIAYKQ
                     PITRIEIDAIRGVNSSGALAKLQAFDLIKEDGKKEVLGRPNLYVTTDYFLDYMGINHL
                     EELPVIDELEIQAQESQLFGERIEEDENQ"
     gene            30755..31477
                     /locus_tag="VVR63_000451"
     CDS             30755..31477
                     /locus_tag="VVR63_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEU6128503.1"
                     /translation="MRINKYIAHAGVASRRKAEELIKQGLVTVNGQVVRELATTIKSG
                     DKVEVEGQPIYNEEKVYYLLNKPRGVISSVTDDKGRKTVVDLLPNVKERIYPVGRLDW
                     DTSGVLILTNDGDFTDEMIHPRNEIDKVYVARVKGVANKDNLRPLTRGLEIDGKKTKP
                     AVYEILKVDPVKNRSVVQLTIHEGRNHQVKKMFEAVGLQVDKLSRTRFGHLDLTGLRP
                     GESRRLNKKEISQLHTMAVTKK"
     gene            31477..31719
                     /gene="yidD"
                     /locus_tag="VVR63_000452"
     CDS             31477..31719
                     /gene="yidD"
                     /locus_tag="VVR63_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HEU6128504.1"
                     /translation="MKRILIAPVRFYQRFISPVFPPSCRFELTCSNYMIQAIEKHGFK
                     GVLMGLARILRCHPWSKTGKDPVPDHFSLKRNQEGE"
     gene            complement(31944..32909)
                     /locus_tag="VVR63_000453"
     CDS             complement(31944..32909)
                     /locus_tag="VVR63_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU6128505.1"
                     /translation="MKTSLKLYFTALVASFLLLLGACSTNSSTSQTETSSSAPTEVTI
                     KSSLAEVKLSKVPEKIVTFDLGAADTIRALGFEKNIVGMPTKTVPTYLKDLVGTVKNV
                     GSMKEPDLEAIAALEPDLIIASPRTQKFVDKFKEIAPTVLFQASKDDYWTSTKANIES
                     LASAFGETGTQKAKEELAKLDKSIQEVATKNESSDKKALAILLNEGKMAAFGAKSRFS
                     FLYQTLKFKPTDTKFEDSRHGQEVSFESVKEINPDILFVINRTLAIGGDNSSNDGVLE
                     NALIAETPAAKNGKIIQLTPDLWYLSGGGLESTKLMIEDIQKALK"
     gene            complement(33005..33757)
                     /locus_tag="VVR63_000454"
     CDS             complement(33005..33757)
                     /locus_tag="VVR63_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000764290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU6128506.1"
                     /translation="MKLENIDKSIQKQDILQGISLEVSPQKLTAFIGPNGAGKSTLLS
                     IMSRLTKKDQGVLSIKGREIESWNSQELAQELTILKQKINYQAKLTVEELVSFGRFPY
                     SRGRLRSEDWEKIRETLNYLELTNLKDRYINSLSGGQLQRVFIAMVLAQDTDFILLDE
                     PLNNLDIKQSVSMMQILRRLVEELGKTIIIVLHDINIASQYADEIVAFKDGQVFSKGR
                     TDQIMQADLLSQLYEIPITLADINDKKICIYS"
     gene            complement(33754..34710)
                     /locus_tag="VVR63_000455"
     CDS             complement(33754..34710)
                     /locus_tag="VVR63_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HEU6128507.1"
                     /translation="MQTKSKHTKLFWILIILAIGACLLYFWPITHLSAFAWKLRSQKI
                     IVYLLVAIATGISTISFQTLTENRFLTPSILGIESFYVLLQTLLLVFESKFLQLGKSP
                     ILEFLVLLLVQSLFFLALQGYLKTLMKQDLVFILLICLALRSLFRNISTFLQVLMDPN
                     EYDKLQNSLFASFQHLNTSILAIGSLIILALTIFFFRKAVVLDVLHLQRETAQILGLD
                     VEKEQKELLWGIVLLTSTATALVGPMAFFGFMLANLTYLIVKDYQHKLLFIVAILVGF
                     ISLTLGQALIERVFALEIRISMIIESVGGFLFFILLYRRARQ"
     gene            complement(34700..35659)
                     /locus_tag="VVR63_000456"
     CDS             complement(34700..35659)
                     /locus_tag="VVR63_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6128508.1"
                     /translation="MKLSHYLIGLLLLLVFLSISIGTSDFSWGKLFDFDQQTWLLFQE
                     SRLPRTISILLTASSMSMAGLLMQTITQNQFAAPSTVGTTEAAKLGMVLSLFVFPSAS
                     LTQKMLFAFVSSIVFTLFFLAFMTIFTVKERWMLPLIGIIYSGIIGSVTEVIAYRFNL
                     VQSMTAWTQGSFSMIQTHQYEWLFLGLIILITVWKLSQTFTIMNLGKETSESLGISYS
                     LLEKLALFLVALTTSVTMITVGGLPFLGVIVPNLVRKRYGDNLSQTKLMVALVGANLV
                     LACDILSRVLIRPYELSVSLLLGIIGSLVFILLLWRGGRKDAD"
     gene            complement(36082..36783)
                     /gene="galE"
                     /locus_tag="VVR63_000457"
     CDS             complement(36082..36783)
                     /gene="galE"
                     /locus_tag="VVR63_000457"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEU6128509.1"
                     /translation="MTKTILVTGGTSYIGSHTVKALLNAGYKVHVLDNLSTGNRAAVD
                     SRASFKELDVYDASALKAYLEENQIDAVLHCAGEIVVSESIENPSKYFTANVAGMNQV
                     LKVLSEVGIQKIMFSSTASLYGNNCIDKPVTEDTLLDPVNPYAETKLMGERMIYWMAN
                     RYDWKYVIFRYFNVAGAEMDASNGLRVKNPTHIIPNINKTALGQNDSLKIFGDDYDTR
                     DGSCIRDYIYVLDLA"
     gene            37184..38248
                     /gene="pepA"
                     /locus_tag="VVR63_000458"
     CDS             37184..38248
                     /gene="pepA"
                     /locus_tag="VVR63_000458"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HEU6128510.1"
                     /translation="MTTLFSKIKEVTELAAVSGHEAPVRAYLREKLTPHVDEVVTDGL
                     GGIFGIKHSEAVDAPRVLVASHMDEVGFMVSEIKPDGTFRVVEIGGWNPMVVSSQRFK
                     LLTRDGHEIPVISGSVPPHLTRGKGGPTMPAIADIVFDGGFADKAEAESFGIRPGDTI
                     VPDSSAILTANEKNIISKAWDNRYGVLMVSELAEALSGQKLGNELYLGSNVQEEVGLR
                     GAHTSTTKFDPEVFLAVDCSPAGDVYGGQGKIGDGTLIRFYDPGHLLLPGMKDFLLTT
                     AEEAGIKYQYYCGKGGTDAGAAHLKNGGVPSTTIGVCARYIHSHQTLYAMDDFLEAQA
                     FLQALVKKLDRSTVDLIKHY"
     gene            38270..38566
                     /locus_tag="VVR63_000459"
     CDS             38270..38566
                     /locus_tag="VVR63_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEU6128511.1"
                     /translation="MVEPNLESLIKDLYNHARHDLSEDLVAALLETTKKLPTTNEQLQ
                     AVRLSSLVNRELLLNPKHPAPELLNLARFVKREEAKYRGTATSALMYEELFKML"
     gene            39248..39691
                     /locus_tag="VVR63_000460"
     CDS             39248..39691
                     /locus_tag="VVR63_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEU6128512.1"
                     /translation="MKDGHLLAHHIRLLNGRIFQKLLSQDPEALYRGEQGKILAVLWN
                     SETGCATATDIALATGLANNTLTTMIKKLEEQKLVIVSPCGKDKRKKYLVLTELGKSQ
                     KEVGHRVSQKLDTIFYKGFSEEEIHQFEGFQERILANLKEKGNEV"
     gene            39695..40459
                     /locus_tag="VVR63_000461"
     CDS             39695..40459
                     /locus_tag="VVR63_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HEU6128513.1"
                     /translation="MSQQVKNAHNLYIHAIQDGRVAEAQAQSVGDTYIQHSTGVPDGK
                     EGFAAFFADFFERHPERQIKIVRTIEDGNLVFVHVHQYLNGGEAQWVTTDTFRADENG
                     RIVEHWDVIDYYRTPENDQLDQIFGDFEIKDLDKKAENKKLVRRFLTEIFQNGELEQW
                     SDYVADDLIQHNHEIGQGSAAYKNYVAEYSVTFDFVFQLLGQGNYVVSYGQTQIDGVA
                     YAQYDIFRLENGKIVEHWDNKEVMPKVEDLTNRGKF"
     gene            40474..41202
                     /locus_tag="VVR63_000462"
     CDS             40474..41202
                     /locus_tag="VVR63_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6128514.1"
                     /translation="MIEYKNVALRYTEKDVLRDVNLQIEDGEFMVLVGPSGSGKTTML
                     KMINRLLEPTDGNIYMDGKRIKDYDERELRLSTGYVLQAIALFPNLTVAENIALIPEM
                     KGWSKEEITKKTEELLAKVGLPVAEYGHRLPSELSGGEQQRVGIVRAMIGQPKIFLMD
                     EPFSALDAISRKQLQVLTKELHKEFGMTTIFVTHDTDEALKLADRIAVLQDGEIRQVA
                     NPETILKVPATDFVADLFGGSVHD"
     gene            41195..42715
                     /locus_tag="VVR63_000463"
     CDS             41195..42715
                     /locus_tag="VVR63_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HEU6128515.1"
                     /translation="MTNLIATFQDRFSDWLTALSQHLQLSLLTLLLAILLAIPLAVFL
                     RYHEKLADWVLQIAGIFQTIPSLALLGLFIPLMGIGTLPALTALVIYAIFPILQNTIT
                     GLKGIDPSLQEAGIAFGMTRWERLKKFEIPLAMPVIMSGIRTAAVLIIGTATLATLIG
                     AGGLGSFILLGIDRNNASLILIGALSSAVLAIAFNFLLKVMEKAKLRTIFSGFALVAL
                     LLGLSYSPALLAQKEKENLIIAGKIGPEPEILANMYKLLIEENTSMTATVKPNFGTTS
                     FLYEALKKGDIDIYPEFTGTVTESLLQPSPKVSHEPEQVYQVARDGIAKQDHLAYLKP
                     MSYQNTYAVAVPKKIAQEYGLKTISDLKKVEGQLKAGFTLEFNDREDGNKGLQSMYGL
                     NLNVATMQPALRYQAIQSGDIQITDAYSTDAELERYDLQVLEDDKQLFPPYQGAPLMK
                     EALLKKHPELERVLNTLAGKITESQMSQLNYQVGVEGKSAKQVAKEFLQEQGLLKK"
     gene            43060..43866
                     /locus_tag="VVR63_000464"
     CDS             43060..43866
                     /locus_tag="VVR63_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HEU6128516.1"
                     /translation="MHTYLQKKIENIKTTLGEMSGGYRRMVAAMADLGFSGTMKAIWD
                     DLFAHRSFAQWIYLLVLGSFPLWLELVYEHRIVDWIGMICSLTGIICVIFVSEGRASN
                     YLFGLINSVIYLILALQKGFYGEVLTTLYFTVMQPIGLLVWIYQAQFKKEKQEFVARK
                     LDGKGWTKYLSISVLWWLAFGFIYQSIGANRPYRDSITDATNGVGQILMTAVYREQWI
                     FWAATNVFSIYLWWGESLQIQGKYLIYLINSLVGWYQWSKAAKQNTDLLN"
     gene            complement(44033..44569)
                     /locus_tag="VVR63_000465"
     CDS             complement(44033..44569)
                     /locus_tag="VVR63_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEU6128517.1"
                     /translation="MTNIDRRISKTKKAIYQAFIQLLNAKGYEATTVQDIIDLADVGR
                     STFYCHYESKELLLDQLCRYLFHHLFEREQAISTEDYLAHLFLHFHKNQDHITSLLFS
                     KNDYFLRQLHKELEHHVYSVLADNLKEAHPNLPTSYLQHLVMSNFIETLTWWLKKGQD
                     FTDQEVVQFYLDLLIPKN"
     gene            44702..45592
                     /locus_tag="VVR63_000466"
     CDS             44702..45592
                     /locus_tag="VVR63_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HEU6128518.1"
                     /translation="MKAKYAVWVAFFLNLTYAIVEFIAGGVFGSSAVLADSVHDLGDA
                     IAIGISAFLETISNREEDNQYTLGYKRFSLLGALVTAVILVTGSVLVILENVTKILHP
                     QPVNDEGILWLGIIAITINLLASLVVGKGKTKNESILSLHFLEDTLGWVAVILMAIVL
                     RFTDWYILDPLLSLVISFFILSKALPRFWSTLKIFLDAVPEGLDIKQVKSGLERLDNV
                     ASLNQLNLWTMDALEKNAIVHVCLKEMEHMETCKESIRIFLKDCGFQNITIEIDADLE
                     THQTHKRKVCDLERSYEHQH"
     gene            45836..46189
                     /locus_tag="VVR63_000467"
     CDS             45836..46189
                     /locus_tag="VVR63_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEU6128519.1"
                     /translation="MNIKSASDLLGISADTIRYYERVGLVPPITRTATGIRDFQDQDI
                     EALEFIKCFRSAGVSVDSLVDYMSLYQKGDETREERLGILEEEKQKLEERLSQLQTAL
                     NRLNLKIKLYKEGKF"
     gene            46190..47227
                     /locus_tag="VVR63_000468"
     CDS             46190..47227
                     /locus_tag="VVR63_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HEU6128520.1"
                     /translation="MKSAVYTKAGQVGLASIERPQIIEADDVIIRVVRACVCGSDLWR
                     YRNPETKAGHKNSGHEAIGIVEEAGEAITTVKPGDFVIVPFTHGCGECDACLAGFDGS
                     CDNHIGNNLGGDFQAEYIRFHYANWALVKIPGQPSDYTEGMLKSLLTLADVMPTGYHA
                     ARVANVQKGDKVVVIGDGAVGQCAVIAAKMRGASQIILMSRHEDRQKMAMESGATAVV
                     AERGQEGITKVREILGGGADAALECVGTEAAIEQALGVLHNGGRMGFVGVPHYNNRAL
                     GSTFMQNISVAGGAASATTYDKQFLLKAVLDGDINPGRVFTSSYKLEDIDQAYKDMDE
                     RKTIKSMIVIE"
     gene            complement(47273..48280)
                     /gene="galR"
                     /locus_tag="VVR63_000469"
     CDS             complement(47273..48280)
                     /gene="galR"
                     /locus_tag="VVR63_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator GalR"
                     /protein_id="HEU6128521.1"
                     /translation="MATLKDIAQLASVSIATVSRVLNRDQSLSVTEETRHRILTVAEE
                     LGYTKHLKTGESHKPKQKIAIIQWVSEQGELDDLYYYQIRLGIEKRAQELDYDILRYF
                     NDHPFTLSEEVIGILCIGKFSRAQISAFEEYQKPLVFLDSDTLSLGHTCIITDFYTAM
                     KQVVDYFLSQGMDRIGILTGLEETTDQEEIIQDKRLENFKNYSQARGIYHDELVFQGR
                     FTAQSGYDLMKEAIQSLGDQLPPAFFAASDSLAIGALRALQEAGISLPDRVSLISFND
                     TSLTKQVYPPLSSITVYTEEMGRAGMDILNKEVLHGRKIPSLTMLGTRLTLRESTLNQ
                     E"
     gene            48445..49623
                     /locus_tag="VVR63_000470"
     CDS             48445..49623
                     /locus_tag="VVR63_000470"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HEU6128522.1"
                     /translation="MAQHLTTEVLRKDFLAVFGQEADQTFFSPGRINLIGEHTDYNGG
                     HVFPAAISLGTYGAARKRDDQVLRFYSANFEDKGIIEVPLADLKFEKEHNWTNYPKGV
                     LHFLQEAGHVIDKGFDFYVYGNIPNGAGLSSSASLELLTGVVAEHLFDLKLDRLDLVK
                     IGKQTENNFIGVNSGIMDQFAIGMGADQRAIYLDTNTLEYDLVPLDLKDNVVVIMNTN
                     KRRELADSKYNERRAECEKAVEELQVALDIQTLGELDEWAVDQYSYLIKDENRLKRAR
                     HAVLENQRTLKAQAALQAGDLETFGRLMNASHVSLEHDYEVTGLELDTLVHTAWAQEG
                     VLGARMTGAGFGGCAIALVQKDTVEAFKEAVGKHYEEVVGYAPSFYIAEVAGGTRVLD
                     "
     gene            49642..51123
                     /locus_tag="VVR63_000471"
     CDS             49642..51123
                     /locus_tag="VVR63_000471"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HEU6128523.1"
                     /translation="MILVDKFVTHVISESSFEEMDRIYLTNRVLARVGEGVLEVETNL
                     DKLIDLKDQLVEEAVRLEMIEDSQTAREILGTELMDLVTPYPSQVNRDFWEAYVHSPE
                     QAIEDFYQLSQKNDYIKLKAIAKNIAYRVPSDYGELEITINLSKPEKDPKEIAVAKLV
                     QASNYPQCQLCLENEGYHGRVNYPARSNHRIIRFEMVGQEWGFQYSPYAYFNEHCIFL
                     DGQHRPMAISRQSFERLLAIVEQFPGYFAGSNADLPIVGGSILTHDHYQGGRHVFPME
                     LAPLQKTFRFAGFEQVKAGIIKWPMSVLRLTSDSKEDLINLADKIFQEWRQYSDSSVQ
                     ILAETDGTPHHTITPIARKRDGQFELDLVLRDNQTSAEHPDGIYHPHKDVQHIKKENI
                     GLIEVMGLAILPPRLKEEVEQVASYLVGEAVTVADYHQEWADQLKSQHPDLTDKEKAL
                     AIVKDSVGAIFARVLEDAGVYKQTEQGQTAFMRFVEHVGILLD"
     gene            51193..51597
                     /locus_tag="VVR63_000472"
     CDS             51193..51597
                     /locus_tag="VVR63_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HEU6128524.1"
                     /translation="MKDFHFDAISAFENYEIEKMRDGHVVVTTKVVNSSLNYYGNAHG
                     GYLFTLCDQISGLVVISLGLDGVTLQSSINYLKAGKLDDVLTIKGECVHQGRTTCVMD
                     VDITNQEGRNVCKATFTMFVTGQRSEERQVRI"
     gene            complement(51643..52908)
                     /gene="dcm"
                     /locus_tag="VVR63_000473"
     CDS             complement(51643..52908)
                     /gene="dcm"
                     /locus_tag="VVR63_000473"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
                     /protein_id="HEU6128525.1"
                     /translation="MKVLELFAGVGGFRIGLENADKQLFKTKWANQWEPSRKSQDAFE
                     VYDYHFPNSKNINISISDITDEQFSKMDADMIVGGFPCQDYSVARSKKNEKGIEGKKG
                     VLFWEIIRATEIIKPKYLILENVDRLLKAPSKQRGRDFAIMLTAFNNLGYSVEWRVIN
                     AAEYGRSQRRRRVFFFVYRNDTVFAQKIDNLYEKNEEIFEDNRYDDYIFNQGLFAKQF
                     PIKPIAVKNRHVFYELPNDIVEVSDTFTGTVWNTGIMRRGKYYSIDTEPNYNGNPITL
                     GEILQDESEVPEKYFLTDQSKLEKFQYLRGPKKIERTSSDGHQYIYSEGGMSPYDDLN
                     LPGRTMLTSEGTVNRSTHLLFVNNKYRLITPIEAERLQDFPDDWTAKKKLSDDSIVEV
                     SDKMRMFFMGNALVTEIVKEIAKFIKEID"
     gene            53025..54515
                     /locus_tag="VVR63_000474"
     CDS             53025..54515
                     /locus_tag="VVR63_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000372610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutH"
                     /protein_id="HEU6128526.1"
                     /translation="MDQNLFNYNDEDIDSVIEYSHKLLNRKFSDVMEEYNRSLYKSYD
                     DYNDRVVSEVQDKAISMKSKGQYGNYIEKYFYGYQPNSDSEADFEKIGVELKVTPFKI
                     NKNGTLSAKERLVLTILNYMEENLEDFYSTHLWKKCAKILLLFYNGLIPNQTMKDYVI
                     EKIFLYEWFEEDMAVILEDYQKITDKIKNGKAHELSESDGNYLSTCTKGAGKGKDLRQ
                     QPFSHELAKQRAWELKSSYMTYLINHKIFNQSDQESVLANFRGEKKSFTEVIAEKILS
                     YKGFSEQELYDRFEVNSKAKGKNSTLIRKILGLTGDLDKTKEFQKANMNLRVIRVDKN
                     NLPKEDSPFKTYCFKELAATDSWESSHVYNEIYNKRFLFVIFKEIEPKLFVLDSIKFW
                     GFQDRQLEEIQRVWQETRQIISDGVKLTQNGNKVSTNFPQSKINKILFTKLHATNTYY
                     EIDKGKFVGKGSLSDTDELPDGRRITKHSFWMPKKFIKEILDGNWD"
     gene            complement(54570..>55441)
                     /locus_tag="VVR63_000475"
     CDS             complement(54570..>55441)
                     /locus_tag="VVR63_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001194492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="purine/pyrimidine permease"
                     /protein_id="HEU6128527.1"
                     /translation="ITTIGLTLIPVAIGNMGNNVPEPTGQSLLLAAITVLIILLINIF
                     TKGFIKSISILIGLVVGTAIAATMGLVDFSPVAVAPLVHVPIPLYFGMPTFEISSIVM
                     MCIIATVSMVESTGVYLALSDITKDPIDSTRLRNGYRAEGLAVLLGGIFNTFPYTGFS
                     QNVGLVKLSGIKKRLPIYYAAGFLVLLGLLPKFGALAQIIPSSVLGGAMLVMFGFVSI
                     QGMQILARVDFANNEHNFLIAAVSIAAGVGLNNSNLFVSMPTAFQMFFSNGIVVASLL
                     TIVLNAVLNHKKK"
BASE COUNT        16215 a        10117 c        12443 g        16666 t
ORIGIN      
        1 ccataatatc cataggggat ttacccacta caaatattat agagccttat attataattg
       61 tgttatttta cttccaacta ttgagagaaa tttcgccact atttagccag atttcttttc
      121 cgttatcaca ttgaactaaa agttttccat tttctgagat gtctttagca agtcccttgt
      181 agtctttttg ctgtagtgtg aaagtgactt cttttcctag aatgaatgac tgttttttgt
      241 ataggtataa tagctcttct gctggtgttt cgaagaaagc acgccagatt tctatgatca
      301 attcattcct tgttatagga gctgtagctt taaataagct ggcagctttt tcttttaatt
      361 cctgagggaa gtctttaata gtgaaattga tacctactcc aataatgata tctgtgacta
      421 agccagtttc tacagaggtc attgcttcag taaggattcc tccaatttta tgattgttta
      481 gatagatatc attgacccat tttatgtcga catctattaa agttaggttc ttaatagctt
      541 tgtagacagc tccagctaca agtagtgtgt aggatggtaa tttgtcatag gggagatttg
      601 gtttaagatg gagtgtcata taaataccac cttgtggtga gtagaaggaa cgttgaaaac
      661 gtcctcggcc tgctgtttga taggaagcta gatagagggt atttgcttca tggcctaaat
      721 caattgcttc ttttgcatct agttgtgttg attttgtttc gggtttaaag ctgactttaa
      781 ttggaagatt ttcttctaga atctctggaa gaataaggtc accattcatt agtttatatc
      841 ctctattttt gatactatca atttcaatgc cttcttgttc tagtcgcttg atagctttcc
      901 aaattgatgt tcggcttagg gatagttttt ctgcgatttt ttctccgctg atatagtcgg
      961 tttctttaga taggatttgg tagacagctt ggtaggattt cataatgttg cctttctcac
     1021 tagttggtat tgagagtatt cttttcttgt atgacttgga gtctgattaa agtattgttt
     1081 ataagctttc gaaaaatgga gtggatctga aaaacctacc gagtatgcaa ttaccttgat
     1141 ggactcttgg gtattttcga gaagttgtct agctcggtgc attcgaacgt agagtaggta
     1201 ttctttgggt gataaggtat taaattcttt gaatacgctt gataagtagc ttctgtgaac
     1261 ggatagttct tttgctaaat cttgaattgt aagtgattga ggatagtggc tatcaattaa
     1321 tcgtttgcat tcaagataga gttggtgggt tgatgaaata ttcttttttt tctgattggg
     1381 agcaatagtt cccagatgaa acatcagttc atgaagttgt cccatgatat ggagttgagc
     1441 taattcactt gattttgtaa tctgagcgaa gcggacaatg tctgagatga gttttgcagt
     1501 agtctgggta tgacaagttt cagattggat gagataggat tgatcagaaa tttgggaaag
     1561 agcaaaataa tcaggggctt tccctccagt gattcctaac cagtagtagg cccaaggttc
     1621 tttactatct gcttgataaa aggttagttc ctctggtttt aatagaaaga aatctccttc
     1681 ttttaaatca acaattttac ccttgtaatg aaattttcct tgtcctttag taatgtaatg
     1741 tagaacgtat gtatcacgaa tggctggacc aaaagagtaa ttaggtgtgc attcctcata
     1801 tccataaaag cttagggcaa ggtcgattgt tccagtctgg tattctgaaa aaactaacat
     1861 gtgctacctc ctacctaaca ttttaccata ttcttgagac atttttctat tttggaaagc
     1921 gatttcaggt gataaaatat aatcaataaa gtgatgaggt gaagtaaatg ggagttagga
     1981 tagagaataa tctattttat gttgagagta aaaatctaag tttgattatt gaaaatcgaa
     2041 atggctactt acttttgaaa catttaggaa agactattaa gaactataaa ggttccaata
     2101 gtgtttatga acgagaccat gccttttcag gaaatccaac ggctactaat cgaaccttta
     2161 gtttagatac tcaacgtcaa atttttggac aacatggctt aggagatttt aggaaaccaa
     2221 ccatacaggt tcagcataat gtaactgaag taacagactt tcgatttgta gaagcaaaga
     2281 ttttaaaagg tcagaatggt ccacagggct taccttctcc acatagcatg gacgatacag
     2341 agactcttgt cttaatgtta gaagattcta aggctcaact tagtctgact ttgtattata
     2401 ctacttttaa taatgatgcg actattgcta gctacagtaa attagataat aatagtaatc
     2461 aggaagttgt catccataaa gatttttctt ttatggctga ttttccagct gcagattatg
     2521 aaatagcaac tctgcagggt gcttatgctc gtgaaaagac tgttagacgt caacaggtag
     2581 aacaaggaat cttttcgatt agttcaaacc gaggtgcttc tggtcatgct caaacaccag
     2641 ctcttctact atgcgaacaa ggagtcacag aggatgctgg gaatgtgttt gctattcaac
     2701 taatgtatag tggcaacttt gaagcttttg ttcaaaaaaa tcaattgaat gaagttcggg
     2761 tggctattgg cattaatcca gaaaactttt cttggaagtt agcccctgag gaatactttg
     2821 aaacaccggt agctttagtg actcattcag atcagggatt aactggtatt agtcatgaaa
     2881 gtcagaattt tgtactgaag cacattatgc taagtgaatt ttctaaaaaa gaacgtccaa
     2941 ttctaatcaa taactgggaa gctacttact ttgactttca gagagaaaaa ctgttagagt
     3001 tagcagatga agctaagaaa gttggcattg aactttttgt attagatgat ggttggtttg
     3061 gcaatcgttt tgatgataat cgtgctttag gtgattgggt tgttaatgag gaaaaactgg
     3121 gtggaagtct agaaagtctg atttcagcta tccatgaaag aggtttgcag tttggacttt
     3181 ggttagaacc cgaaatgatt tctgtagata gtgatttgta tcgtcaacat cctgactggg
     3241 ctattcaggt tcctgattat gagcatactt attctcggaa tcaattagta cttaatcttg
     3301 ccaatcctca ggtagtagaa tacttgaaaa gtgtcttaga tcaactccta tcttatcatg
     3361 agattgatta cattaaatgg gatatgaacc gcaatatcac taagctaggg aatggattaa
     3421 cttatctaga gacacagatg caatctcatc agtacatgct ggggctttac gaactcgttt
     3481 cttatctgac agagaagcac agccatattc tctttgagtc ctgctctggt ggtggtggac
     3541 gaaatgatct tggtatgata cgctatttcc cacaagtctg ggctagtgat aatactgatg
     3601 ccattgcacg tttaccaatt caatacggtt catcctatct ctatccaacc atttctatgg
     3661 gggctcatgt gtcagcagta ccgaatcatc agatgggacg aatgacacca ttagaaacac
     3721 gtggccatgt agcaatgatg ggaaatttgg gctatgagct tgatttgaca aatttatcag
     3781 atgaagagaa agctacgatt gctaatcagg tgaacttgta taaagaatta cgaccagtag
     3841 ttcagttagg acagcagtat agactaatta atcctgatac tgcatccaat gaagcagctg
     3901 tacaatttaa ttacggaaat caaacgattg taacctacgt tcgcgtttta tctgttgtag
     3961 agaccatgga aacaacttta aaattaaaag atttggatga agagggacta tataaattac
     4021 aggaaaatgg cgaagtttac tcaggtgcag aactaatgta tgcgggctta actgttatct
     4081 tatcccaagg agattttttg agtagacagt atatttttag aaaactatga tatgtactga
     4141 ccccaaaagt tagatttatt ctgtctaact tttggggtgc agttcaataa gggtgtataa
     4201 atttataaag gaggctttct aatggaatgg tataaaaaaa tcggacttct tgcaactaca
     4261 ggtttagctt tggttgggct cggcgcttgc tccaactatg gtaaatctgc ggatggcaca
     4321 gtgaccatcg agtatttcaa ccagaaaaaa gaaatgacca aaaccttgga agaaatcact
     4381 cgtgattttg agaaggaaaa ccctaagatc aaggttaaag tcgtcaatgt accaaatgct
     4441 ggtgaagtat tgaagacacg cgttctcgca ggagatgtgc ctgatgtggt caatatttac
     4501 ccacagtcca tcgaactgca agaatgggca aaagcaggtg tctttgaaga tttgagcaac
     4561 aaagactacc tgaaacgcgt gaaaaatggc tacgctgaaa aatatgctgt aaacgaaaaa
     4621 gtttacaacg ttccttttac agctaatgct tatggaattt actacaacaa agataaattc
     4681 gaagaactgg gcttgaaggt tcctgaaacc tgggatgaat ttgaacagtt agtcaaagat
     4741 atcgttgcta aaggacaaac accatttgga attgcaggtg cagatgcttg gacactcaat
     4801 ggttacaatc aattagcctt tgcgacagca acaggtggag gaaaagaagc aaatcaatac
     4861 cttcgttatt ctcaaccaaa tgccattaaa ttgtcggatc cgattatgaa agatgatatc
     4921 aaggtcatgg acatccttcg catcaatggc tctaagcaaa agaactggga aggtgctggc
     4981 tataccgatg ttatcggagc cttcgcacgt ggggatgtcc tcatgacacc aaatgggtct
     5041 tgggcgatca cagcgattaa tgaacaaaaa ccgaacttta agattgggac cttcatgatt
     5101 ccaggaaaag aaaaaggaca aagcttaacc gttggtgcgg gagacttggc atggtctatc
     5161 tcagccacca ccaaacatcc aaaagaagcc aatgcctttg tggaatatat gacctgtcca
     5221 gaagtcatgc aaaaatacca cgatgtggac ggatctccaa cagcgatcga aggggtcaaa
     5281 caagcaggag aagattcacc gcttgctggt atgaccgaat atgcctttac gggtcgtcac
     5341 ttggtctggt tgcaacaata ctggaccagt gaagcagact tccatacctt gaccatgaac
     5401 tatgtcttga ccggtgataa acaaggcatg gtcaatgatt tgaatgcctt ctttaacccg
     5461 atgaaagcgg atgtggatta ggagtagaga gactatgaaa aaagtattac aaaaatattg
     5521 ggcatgggct tttgtggtca tccccctctt gttacaagca attttcttct atgtgccgat
     5581 gtttcaagga gccttttaca gttttaccaa ctggacagga ttgacttaca actacaaatt
     5641 tgtcggctta aacaacttta agctcctctt catggatcca aaattcatga atgcgattgg
     5701 ctttaccgca atcattacga ttgccatggt ggttggtgag attgcactcg ggatcttcat
     5761 tgcgcgtgtc ttgaactcta aaatcaaagg ccaaaccttc ttccgtgctt ggttcttctt
     5821 cccagctgtt ttatctggtt tgacagtggc tttgatcttc aagcaagtct tcaactacgg
     5881 tcttccagcg attgggaatg cccttcatat tgaatttctc caaaccagtc ttttagggac
     5941 taagtgggga gcaatctttg cggctgtctt tgtccttctt tggcaagggg tggctatgcc
     6001 catcatcatc ttcctagctg gtttgcaatc tattccaact gagattacag aggcagcaag
     6061 gattgatggt gcgactagca agcaagtttt ctggaacatt gaattgcctt acttgctacc
     6121 aagtgtctct atagtcttta tcctagccct aaaaggtggg ctgactgcct ttgaccaagt
     6181 ctttgccatg accggtggtg gtccaaacaa tgccacaacc tcacttgggc ttttggttta
     6241 taactatgcc tttaaaaaca accaattcgg ttatgccaat gccattgccg taatcttgtt
     6301 cttcttaatt gtagtgattt cgatcatcca attgagagta tctaagaaat ttgaaattta
     6361 agaggagaag catgatgaaa caagatgaaa gaaaagccct gattggcaaa tacattctat
     6421 tgattctagg atcggttctg attttagtgc cgctccttgc taccctcttt agttccttca
     6481 aatccactaa ggatattgta gataatttct ttggctttcc aaccaacttc acatgggaca
     6541 actttagccg tctcttagct gatgggattg gaggctatta ttggaactct gtcgtcatca
     6601 ctgtcttgtc tttacttgca gtaatgatct ttatccctat ggcagcctac tccatcgctc
     6661 gcaatatgag taaaagaaaa gcctttacca tcatgtatac cctcttaatc ctcggaatct
     6721 tcgtaccttt ccaagtcatc atgattccga ttacggttat gatgagtaaa ctcggtttgg
     6781 ctaatacctt tggtttgatc ttgctctact tgacctatgc gattccacag accctctttc
     6841 tctatgttgg ctatatcaaa atctcgattc cagaaagtct ggatgaagca gcagagatcg
     6901 atggggctaa tcaatttaca acctatttcc gcatcatctt cccaatgatg aaaccgatgc
     6961 atgcgacaac catgatcatc aatgcccttt ggttctggaa tgacttcatg ttgccactcc
     7021 ttgtcttgaa ccgggattcc aaaatgtgga ctctgccttt gttccaatac aactacgcag
     7081 gccaatattt caacgactac ggaccaagct ttgcctctta cgtggtcggc attatcagta
     7141 tcaccattgt ctatctcttc ttccaacgcc atatcatttc aggaatgagc aacggggcag
     7201 tgaagtaata ctcaatgaaa atcaaagagc aaactaggaa gctagccgca ggctgtactt
     7261 gagtacggta aggtgaagct gacgtggttt gaagagattt tcgaatagta taagaagagc
     7321 tcatggaatc tatagtcttt gacacagagg aagagttcag cttgttgata attctatgta
     7381 gaaaacaaga aagtagtact ttgtttatca cagtctatat tagtacgagt ttgatgataa
     7441 atagagattt aaaatgaatt ttatttatga aggcagatca tatgagactt ggcttcaatt
     7501 agaaaaagga gagtaatgat gccaattcaa aataaaacca tgttgattac ctattctgat
     7561 agccttggaa ataatcttaa agacttatat gataatttgg aagagcattt tggagatgct
     7621 attggaggag ttcacctttt accatttttc ccatcaacag gtgatcgtgg atttgcgcca
     7681 gttgactacg acgaagtgga ctcagctttt ggtgattggg aggatgttaa gcgtttaggt
     7741 gagagatatt atcttatgtt tgattttatg attaatcata tttctcgtca atccaagtat
     7801 tataaggact atcaagaaaa acatgaagcc agtgaattta aagatctctt tttaaactgg
     7861 gataagtttt ggccagaaaa ccgtccgaca cagtctgatg tagatttaat ttacaagcgt
     7921 aaggatcgtg caccaaagca agagattgtg tttgaagatg gttcagtgga acatttgtgg
     7981 aatacctttg gtgaggagca gattgatctt gatgtgacca aagaagtaac tatggaattt
     8041 atccgtaaga ccattcagca cttggcaagt aatgggtgtg atttgattcg tctagatgcc
     8101 tttgcttatg cagtgaagaa attggatact aatgatttct ttgtggaacc agatatttgg
     8161 gatttattgg acaaagttcg agatatcgct gctgagtatg ggacagagct tttacctgag
     8221 attcatgaac actattcgat tcagtttaaa atagcagacc atgattacta tgtttatgat
     8281 tttgctcttc caatggtgac actttatact ctttacagtt ccagaacaga gcgtttggct
     8341 aagtggttaa agatgagccc gatgaagcaa tttacgacgc tagataccca tgatgggatt
     8401 ggagtagtag atgtcaagga tatcctgacc gatgaggaga ttgactatgc ttcaaatgaa
     8461 ctctataagg ttggagccaa tgtcaaacgt aagtactcta gtgccgagta taacaactta
     8521 gatatctacc aaatcaattc aacctactat tcagcgcttg gagatgatga tgtcaagtat
     8581 tttctcgctc gtctaattca agcttttgcc ccaggtattc ctcaggttta ctatgtgggt
     8641 ctattagcag gcaagaatga cttgaaatta ttagaagaaa ctaaagaagg tcgaaatatt
     8701 aatcgtcatt actatagcaa cgaggaaata gcaaaagaag tgcaacgatc tgttgtgaag
     8761 gcccttctca atctattttc tttccgtaac cgttcagaag cctttgatct agaagggact
     8821 attgagatag agacaccaac agttcacagc attgtaatca aacgtcaaaa taaagataag
     8881 tccgtaacag cagtagcaga aattgatttg caaaatcaga cttatcgggt aattgagaat
     8941 ggagttgaag taacattttg aagccttgat atggtggata aaatagggtt tttattttgg
     9001 aaaacgtttc ctttgttttc aaattgctaa aaaagtggta caatatagga tagcttacta
     9061 ttatctgaat cagctgattt ggagagaaag gattcatttt gaaatcaata ggctttattg
     9121 aaaagctgaa ggggttgtct agtaaagagc tgattttatt gggaattatc ctgagtatct
     9181 ttttaccctt ttatcttttt gtagttgtac tctgtttata tattatcagt ttgattttta
     9241 caggagacat gaaaagtatt cttcagaaaa tgggggagca tccgatgctg cttctttttc
     9301 ttagctatag tactgttata tccattcttg cacaaaattg gatgggtctt gtggcttcag
     9361 taggaatgtt tctatttact attttctttt tgcactatca gtcgatttta tcccataaat
     9421 tctttcgatt gattttgcag ttcgtcttgt ttggtagtgt cttgtcagct gcttttgcca
     9481 gtttagaaca tttccaaatt gtgaagaaat ttaactatgc ttttctttca cccaatatgc
     9541 aggtgtggca tcagaaccgg gcagaagtga ccttctttaa tcctaattat tatggaatta
     9601 tttgttgttt ctgtattatg attgctttct atctgtttac aacgaccaag ttgaattggt
     9661 tgaaagtatt ctgtgtgatt gcaggctttg ttaatctctt tggtttgaac tttactcaaa
     9721 atcgaactgc ctttcctgct attatcgctg gagcaattat ctatctcttt acgactatta
     9781 aaaactggaa ggctttttgg cttagtattg gggtcttcgc gattggtttg agtttcctct
     9841 tttctagtga tttgggagtt cgaatgggta ctttagactc ttctatggaa gaacgcattt
     9901 ctatctggga tgctgggatg gccttgttta agcaaaatcc tttttggggt gaagggccat
     9961 tgacctatat gcactcttat cctcggatac atgctcctta tcatgaacat gcccacagtc
    10021 tttatattga tacgattctg agttacggaa ttgtgggtac cattttatta gttctgtctt
    10081 ctgttgctcc tgttcgtttg atgatggata tgagtcagga gtcggggaaa cgtccgatta
    10141 tcggccttta tctatctttc cttacagtgg ttgctgtgca cggaattttt gacttggctc
    10201 tcttctggat tcagtcaggc tttattttct tgctagttat gtgcagtatt ccattggagc
    10261 atcgaatgtt ggtatcggac atgacggatt aagttttata agtttgaaat cttctacctt
    10321 gggtaggaga tttttttata cgatgggcat gtcgtgcatc tgaggtgtaa gtcctctgta
    10381 gggatccact accggtgaat acaatagcgc tccccaagcc tgactatcgt gaggtagcgg
    10441 attaaaatgg tctggggata gatcgtttta agtctgacgc aggaaataag aattgtcaga
    10501 gaaagcaata gtgaaatcgt aggctatgaa tagaaacgtg atagcgagga gcatatagtg
    10561 gacaaggtag cgagaaattt taaagtataa aagatagtct taatctatat gtgtaaatca
    10621 cgaaagtaat tgaattcgga ataaggttgg tgtgaaaaga catagtaaac tgaatcttga
    10681 atactagaat gatacttcta caatattgtt ataatttaat ttgaattcca aaatcacatt
    10741 gttccgtccg tatttcattt tactgtatgt cttcctaagc tccaaaattt ctgtgtcaaa
    10801 tttcctattt tcactgtagt ctttgacact tcgaacgaca atttgaatca tatattcaaa
    10861 aaaaaatgaa aaatttgtgc caacaagcct aaatattctg aaaatttgtt tgatttttaa
    10921 tggataatgt gatataatgg ttgtcaatct ataattcaca taaacagagg agtagaaaat
    10981 gaaaaaaaat cgtgtatttg ctacagcagg tcttgtttta ttagcagcag gtgtacttgc
    11041 agcatgcagt tcttcaaaat catctgattc atcagcccct aaagcttatg gctatgttta
    11101 tacagcagac ccagaaacct tggactacct gatttcaagt aaaaatagta caacagtagt
    11161 gacttcaaat gggattgatg gtttattcac taacgataat tacggtaatc ttgctcctgc
    11221 agttgcagag gattgggaag tctctaagga tggtttgacc tacacttata agattcgtaa
    11281 aggggttaaa tggtttacct ctgatggaga agaatatgca gaggtgacgg ctaaagattt
    11341 cgtgaacggt ttaaaacacg cagcagataa aaaatcagaa gctatgtatt tagctgaaaa
    11401 ttcggttaaa ggcttggcag attatctatc aggaacttca acagattttt caacagttgg
    11461 tgtcaaggcg gttgatgatt atacgttaca atacactttg aaccagcctg aaccgttctg
    11521 gaactctaag ttgacctatt ctattttctg gcctctgaat gaagaattcg aaacatcaaa
    11581 aggaagcgat tttgctaaac caacagatcc gacatccttg ctttataatg gtccattctt
    11641 gttgaaaggg ttgactgcaa aatcttctgt agagtttgta aaaaatgagc aatattggga
    11701 taaagaaaat gtccacctag atactatcaa tctagcttac tatgatggat cagatcagga
    11761 gtcgctagag cgtaacttca ctagtggagc ttatagttat gcccgtcttt accctaccag
    11821 ctccaactat tctaaggttg cagaagaata caaggacaat atctattaca cacaatcagg
    11881 ctctgggatt gctggtctgg gtgtgaatat tgatcgccaa agttacaact atacttctaa
    11941 aactacagat tcagagaaag tagctactaa gaaggcattg cttaacaaag atttccgtca
    12001 agccttgaat tttgctcttg atcgctcagc ttactcagct caaatcaatg gtaaagatgg
    12061 agcagcttta gcagttcgta atttatttgt aaaaccagac tttgtttcag ctggtgagaa
    12121 gacctttggt gatttagtcg ctgctcaact tcctgcttat ggtgatgagt ggaaaggtgt
    12181 gaatttagct gatgggcagg atggtttatt caatgctgac aaggccaagg cagagtttgc
    12241 gaaagctaag aaagctttag aagcagacgg cgttcagttt cctattcatc tggacgttcc
    12301 agtagaccaa gcatcaaaaa actatatatc tcgtattcag tcctttaaac aatctgtaga
    12361 aacagttctt ggtgttgaaa atgtcgttgt tgatattcaa caaatgacaa gtgatgaatt
    12421 ccttaatatt acttactatg ctgccaatgc ttcatctgag gattgggatg tatcaggagg
    12481 agtttcatgg gggccagact atcaagaccc atctacttac ctggatattt taaaaacaac
    12541 tagcagtgaa actacaaaaa catatttagg atttgataat ccaaatagcc cttcagtagt
    12601 tcaagttggt ttgaaagaat acgataaatt agttgatgaa gctgccagag agacaagcga
    12661 cttgaatgtc cgttatgaaa aatatgcagc ggctcaagca tggttgacag atagttcact
    12721 ctttattcct gctatggctt cttctggtgc agcaccagtg ctttcacgaa ttgttccatt
    12781 tactggagct tctgcgcaaa caggctctaa ggggtcagat gtttacttca aatatttgaa
    12841 attacaagat aaagtggtga ctaaggaaga gtatgaaaaa gctcgtgaaa aatggttgaa
    12901 agaaaaagct gaatcaaatg agaaagctca aaaagaattg gcaagtcatg tgaagtaaat
    12961 aatttctaat agaactttct ctccatgagg agaaggttct tttgggattt ttaaaggaaa
    13021 taatatgaaa aaatatattt ttatgcgtgt tttgcggtca ttggtttcga ttttcttagt
    13081 aacgactttg acctacacga ttatctatac cttggttcct cgaaaattga ttttcaagca
    13141 ggatcctaac tataataaaa ttgcgacaac ggctgataaa cgtgataact atgaaaatac
    13201 tgtgtttgag cgtatgggct acattgagta ttacgatact aaagagttgc aagaaaaggc
    13261 aagtagcatg gattcttctg taacagtaga agcaaatgcg accaataaag ctatttatga
    13321 aaagtacatc aatcaattag gtcatggttg gactttggga gaatttactg aaagtggtca
    13381 attctatgct actcgtgaaa ttccaatttt tgaacgtgtt tttcacttct atgctaactt
    13441 gattgacatt gatcatacaa ataaaatcca agaccctgaa aatccagact tgaaacgcta
    13501 ccttcgtttt gaaaatgatc cagctatcgg atggtcattg gtcggttcag gaactaaaca
    13561 taaatatctc ttgtacttta acagtcagtt cccatttgtt catcaaaact ttgtgaactt
    13621 gaatttaggt gactcttacc caacctatgc taatacacca gttcttcagg ttattactca
    13681 aggtcaagga caaaccaaaa ctgcccaagt tcagttccca acaggtaaga aaacgtcttc
    13741 tgtaaatatt tactcaagaa cctacaagtc acctagtcag gctgactctc gtgaagtagc
    13801 tagctatggg aaagatgatc cttatacagc gactgaaagt aattaccaat atccatctat
    13861 gattgtcagc tctgctatta ctggtttgat tggtttggtt cttgcctatg ctcttgccgt
    13921 gccacttggt tcagccatgg ctcgtttcaa gaacacttgg attgatagcc tctcaacagg
    13981 gactttgacc ttcttgcttg ctcttccaac gattgccttg gtttacatcg ttcgattgat
    14041 tggatcatct attgcccttc cagattcatt ccctatcttg ggagctggag attggcgttc
    14101 ttacgtttta ccagcagtca tccttggttt gttgggtgct cctgttacag ccatttggat
    14161 tcgtcgttac atgattgact tgcaatctca agactttgtt cgtttcgctc gtgcaaaagg
    14221 tttgtctgaa aaagaaattt caaacaaaca catctttaaa aatgccatgg ttccgctggt
    14281 ttcaggaatt cctggtgcca ttattggggt tatcggtggt gcaaccctta ctgaaacagt
    14341 cttcgccttc ccaggtatgg gtaaaatgtt gattgactct gtaaaagcat ctaataactc
    14401 tatggtcgtt ggtcttgtct tcatctttac atgtatttct atcttctcac gtcttttggg
    14461 agatatttgg atgactatta ttgacccacg tattaaattg actgagaaag gaggcaaata
    14521 atgtctacaa tcgataaaga aaaatttcag tttgtaaaac gtgacgattt tgcctctgaa
    14581 actattgatg cgccagcata ttcttactgg aaatcagtgt ttaaacaatt tatgaagaaa
    14641 aaatcaactg tagtcatgtt gggaatcttg gtagccatca ttttgataag tttcatctac
    14701 ccaatgtttt ctaagtttga tttcaatgat gtcagcaagg taaacgactt tagtgttcgt
    14761 tatatcaagc caaatgcgga gcattggttc ggtactgaca gtaacggtaa atcgctcttt
    14821 gacggtgtct ggttcggagc tcgtaactcc atcctcattt ctgtgattgc gacagtgatt
    14881 aacttggtta tcggtgtttt tgtcggtggt atttggggta tttcaaaatc agttgaccgt
    14941 gtcatgatgg aagtttacaa cgtcatctca aacatcccac ctcttttgat tgttattgtc
    15001 ttgacttact caatcggagc tggattctgg aatctgattt ttgccatgag cgtaacaaca
    15061 tggattggta ttgccttcat gatccgtgtg caaatcttgc gctatcgtga cttggaatac
    15121 aacttggcgt cacgtacttt gggaacacca accttgaaga ttgttgccaa aaatatcatg
    15181 cctcaattgg tatctgttat tgtgacaacc atgactcaaa tgcttccaag ctttatctca
    15241 tacgaagcct tcttgtcttt cttcggtctt ggattaccga ttacagtgcc aagtttgggt
    15301 cgtttgattt cggattattc acaaaacgta acaaccaatg cttacttgtt ctggattcca
    15361 ttgacaaccc ttgtcttggt atccttgtcc cttttcgtag ttggtcaaaa cttagcggat
    15421 gctagtgatc cacgtacaca tagataggag tagaaatgac aaaagaaaaa aatgtaattt
    15481 tgactgctcg cgatattgtc gtggaatttg acgttcgtga caaagtattg acagccattc
    15541 gcggcgtttc ccttgaacta gtcgaaggag aagtattagc cttggtaggt gagtcaggat
    15601 caggtaaatc tgttttgaca aagaccttca caggtatgct cgaagaaaat ggtcgtattg
    15661 cccaaggtag tattgactac cgtggtcagg acttgacagc tttatcttct cacaaggatt
    15721 gggaacaaat tcgtggtgct aagattgcga ctatcttcca ggacccaatg actagtttgg
    15781 accccattaa aacaattggt agtcagatta cagaagttat tgtaaaacac caaggaaaaa
    15841 cagctaaaga agcgaaagaa ttggccattg actacatgaa taaggttggc attccagacg
    15901 cagatagacg ttttaatgaa tacccattcc aatattctgg aggaatgcgt caacgtatcg
    15961 ttattgcgat tgcccttgcc tgccgacctg atgtcttgat ctgtgatgag ccaacaactg
    16021 ccttggatgt aactattcaa gctcagatta ttgatttgct aaaatcttta caaaacgagt
    16081 atcatttcac aacaatcttt attacccacg accttggtgt ggtggcaagt attgcggata
    16141 aggtagcggt tatgtatgca ggagaaatcg ttgagtatgg aacggttgag gaagtcttct
    16201 atgaccctcg ccatccatat acatggagtc tcttgtctag cttgcctcag cttgctgatg
    16261 ataaagggga tctttactca atcccaggaa cacctccgtc actttatact gacctgaaag
    16321 gggatgcttt tgccttgcgt tctgactacg caatgcagat tgacttcgaa caaaaagctc
    16381 ctcaattctc agtatcagag acacattggg ctaaaacttg gcttcttcat gaggatgctc
    16441 caaaagtaga aaaaccagct gtgattgcaa atctccatga taagatccgt gaaaaaatgg
    16501 gatttgccca tctggctgac taggaggaag gaaatgtctg aaaaattagt agaaatcaaa
    16561 gatttagaaa tttccttcgg tgaaggaagt aagaagtttg tcgcggttaa aaatgctaac
    16621 ttctttatca acaagggaga aactttctcg cttgtaggtg agtccggtag tgggaaaaca
    16681 actattggtc gtgctatcat cggtctaaat gatacaagta atggagatat catttttgat
    16741 ggtcaaaaga ttaatggtaa gaaatcgcgt gaacaagctg cggaattgat tcgtcgaatc
    16801 cagatgattt tccaagaccc tgccgcaagt ttgaatgaac gtgcgactgt tgattatatt
    16861 atttctgaag gtctttacaa tcaccgttta tttaaggatg aagaagaacg taaagagaaa
    16921 gttcaaagta ttatccgtga agtaggtctt cttgctgagc acttgactcg ttaccctcat
    16981 gaattctcag gcggtcaacg tcaacgtatc ggtattgccc gtgccttggt catgcaacca
    17041 gactttgtta ttgcagatga gccaatttca gccttggacg tttctgtacg tgcccaagtc
    17101 ttgaacttgc tcaaaaaatt ccaaaaagag ctcggcttga cctatctctt catcgcccat
    17161 gacttgtcgg ttgttcgctt tatttcagat cgtatcgcag ttatttacaa gggtgttatt
    17221 gtagaggttg cagaaacaga agaattgttt aacaatccaa ttcacccata tactcaagcc
    17281 ttgctttcag cggtaccaat cccagatcca atcttggaac gtaagaaggt cttgaaggtt
    17341 tacgacccaa gtcaacacga ctatgagact gataagccat ctatggtaga aatccgtcca
    17401 ggtcactatg tttgggcgaa ccaagccgaa ttggcacgtt atcaaaaagg actaaactaa
    17461 taatggtttt ataatttcca tgtcaatttt tatgggaatt ataaaacttt ttttgttgga
    17521 ctgatttgaa aaactttgaa agcttcctga aagaattttc gaaaaatttt aaaaaatttt
    17581 gaaatattat tgacaggtga tgaaaaaggt ggtaggatag gaaggatcaa aaaagaaagc
    17641 agaaaaagaa atgaataaga gacaagccgt aactatgaat caaaactttt actttagcta
    17701 ctttagatag tgtttgtaga catgtcacca tggatgcaaa cagttcaagc aatttgtttg
    17761 tatctatgtg gctaagattt ttgattgtgg tccatataga tgaatatcta aatggactag
    17821 ctaagttgta acttgttagg ttatttcaag tacccgttta gatagtatct aggcggtttt
    17881 ttgttttatc ttttctgaga aggagtttca ttatgaaagt tgttcgaaaa tcactagccc
    17941 cctcttggta gtggggatcc tcttgacttc tctgatcagt ttgcatcagt tgaaggcaga
    18001 taagaaaaga gatgtctttc gtatcggtat ttcgcagttt attacccacc agtccttaga
    18061 cgctactaga gaaggatttg tggatgagct ggccaaacaa ggctatgttg agggggaaaa
    18121 tattgagatt gatttgcaaa atgcacaggg agaacaaaga aatctaaaaa cgatttccca
    18181 gcaactagca gaatccagcg atgtcgttct agccatcgca aggccttctg ctcagagctt
    18241 ggccaatacg acgcaaacga caccagttat cttttcagct gtaacagacc cagtcagtgc
    18301 caagttggtt gagtcaagag aacatcctgg gggcaatgta actgggacaa gcgatcagtc
    18361 atcagatgcc atttcaaccc aaatcaattt gataaagaaa gtgttgccaa aggctaaaac
    18421 gattggaatc ctctatactc agagcgagcc caattcggtt gtttaaaatg atgaagctaa
    18481 gcgacttctg aaagaaaaag gctttaccgt tgttgaaaaa acaatcttgg acagtaataa
    18541 cgtcaaggcg gcagcagaga gtttgatggc agaggtggat atggtttttg tcccaactga
    18601 taatatcatt tcgtcaacca tggaaacagt taagcaggtt tctattaaac acaaggttcc
    18661 agtattcggt ggttcaacag aaatgattgc tgttggtgac ttgtataact acggaaccaa
    18721 ttatgaagaa ttgggaagac agacagctcg catgctgatt cgtgttttaa aaggtgagaa
    18781 accagaaaat atagcagttg agttgcctga aaaactggaa ttgcatacca atcaagaaat
    18841 ggcagatgca ttgggaattg atattagtaa gtttagaagg caaggaataa ggaggattaa
    18901 gatgaatttt gtgttatcta gtttatcaga aggtttgttg tggtcgattg tggcgattgg
    18961 ggtctacttg actttccgta ttttggatat tgcggatata actgctgagg gagcctttcc
    19021 tctgggggca gcagtcgttg tatcacagat acaggcaggg gcaaatcctt ggcttgcgac
    19081 tttacttgct ttgctggcag gtatggtagc aggtcttgta tcaggaatgc tccacaccaa
    19141 gatgaaaatc ccagctctct tgacagggat tgtgaccttg acagggctct attcaatcaa
    19201 tattaaaatt atgggcagtg tacccaatct ttccttggga gattctgcaa ccgtctttaa
    19261 acagttggcg agcttgggtc tgacaaatga aggagctgtt ttctcactta gtttagtctg
    19321 tctcttactt gtttggtctt gacccttttg atgaaaacag agattggttt ggtcttgcgt
    19381 tcgactgggg ataatatccc gataagtgag gccaatggag tcaatgtaga caccatgaag
    19441 attgttggtt acatgatttc aaacggtttg attgccctat gtggttcctt gtttgcccaa
    19501 aatgatggat tttcagatgt gacttctggg acaggaacca ttgttgttgg tttgagctcg
    19561 gaagtcttga tacacgactt gaccattgga ggccgcttat tatccatcgg aatcggtgct
    19621 attgtttacc gtttgattat tttaaatatc tatgaaattc caaatctaga tcaaaacttg
    19681 gtacgtctct ttaatgcaat cttgctcgct ttggttttat ttgcaccaga attgcaaaag
    19741 agattaaaga ttcgtggtct gaaattgaga aatgaatagg aggagaaagt tatggcaagt
    19801 ttgttaacac ttgaaaatat tcacaagaca tttgaagcag ggacggtcaa tgagaaccat
    19861 gtcctcaaag gattagattt agaggttgaa gagggagatt ttatctatgt gattggtgga
    19921 aatggagcag gaaaatccac tttgatgaat atcttggctg gcaatctatc ggtggacgaa
    19981 ggggaccttc tactggcagg gaaatccatt aaaaatctga gtgtcagaaa gagagccaag
    20041 gatattgccc gtgtttttca atatcctaag atgggaacag cttctcgttt gacgattgag
    20101 gagaatatgg ctattgcctt gagacgtggg caaaagagag ggcttggttg gggtgtgaag
    20161 gagaaggata gaatccagtt ccaagaggcc ttgaaggagt tgaatattgg tcttgaaaac
    20221 cgcttaaaag tagatactca atatctctca ggaggacaaa gacaggcttt gaccctagtc
    20281 atggcagctc tggtgaaacc caaactttta cttttggatg aacatactgc ggcacttgac
    20341 ccgaaaacca gtcaaatggt gatggacttg acgcaaaaga ttgtggagca ccatcagtgg
    20401 acgactttga tgattaccca tgatatgaat catgcgattg agtacggcaa tcgtctcatt
    20461 atgctctatc aaggcaagat agtggtggat gtcaagggag aagagaaaaa gcatctgaca
    20521 gttgaagacc ttatgcatct cttccagaaa aatagtggcc aaagtctggt cagtgatgaa
    20581 ttagttttgg gataaagaaa aaggctgaga tctggtgtct cagtctttta tttcttgcgt
    20641 tttgcaaaat ctacaaatct aaatttttct aacttatggc gactttcggt aaactgaaat
    20701 tggcgtccgt cttggagata gacttttgat ttaatcgaaa cgacataagg gtctttgcca
    20761 atgtccatga gaatcttgtc tcggtcgctt gagtggtcaa tggtgatttc cttctgagca
    20821 taatcaataa ggagtttgag gccattttct atataagaat agatagactg ctcagcaatt
    20881 tggcgagtga gatttgggat gagttccata tccagatagt ccgtatccag aacggatacc
    20941 agatcatcca ccacacgctg gcggaccacc ttccaaacca tccgaaactc tgggaaaccg
    21001 gttatcagtg aggatttttt atcaataata atcttgtcca gactgaccac gttggtttta
    21061 gagcgcagtc caagttcttt aactagttct tggtagctgg ttaggttgga tacagggaaa
    21121 ttgacggttt cttctttgac gacttgagaa ccttgccctc ttatcttttt gatcaatcct
    21181 tcctcttgga ggagagacag ggcctttcgg acggtatcac gactcacttg atattgctcc
    21241 ataaggtcgt gctcgctagg aaggaaatct ccgacagcgt aagtctcgtt ttgaatggtt
    21301 tcttggattt gcttaaataa ttgttggtat ttcttcattt tgcctgcttt aataggtttt
    21361 tagtctagtt taatgaacac ctgtatctat tttaccatac aagtgctaga aaatttacaa
    21421 aaaaacaccc tttttatacc aaacaagttg cagacaagtt tggtatcgtt tacaatatac
    21481 ttatcaaatc aaacttgctt tgacaagtat aaggagaatc aaatgggaaa atttgaacaa
    21541 gaagccaaag atctgcttca ggcaattgga ggcaaagaaa atgtgactgc cgtaactcac
    21601 tgtgcgacac ggatgcgctt tgttttagga gatgataaga aggctaatgt taaagctatc
    21661 gagtcaattc cagctgttaa aggaactttt acaaatgcag gtcaatttca ggtaatcatt
    21721 ggaaatgacg tgcccatctt ttataatgat tttacagccg tttcaggtat tgagggtgtt
    21781 tccaaagaag cagccaagtc tgcagctaag agtaatcaaa acgtggtcca acgtgttatg
    21841 accactctgg cggagatttt tactccgatt attccagctt tgatagtcgg aggattgatc
    21901 ctcggtttcc gtaatgtctt ggaaggtgtc cattggtcga tgttggatgg caagaccatc
    21961 acagaatcct ctcagttttg ggcaggtgtc aatcacttcc tctggttgcc tggtgaagct
    22021 atcttccagt tcttaccagt agggattact tggtctgttt ctcgtaagat gggaaccagc
    22081 caaattttgg gaattgttct cggaatctgt ttggtatcgc ctcagttgct caatgcctat
    22141 gcggttgctt caacgccagc agctgatatc gcggcaaact gggtttggaa ttttggctat
    22201 tttactgtta atcgtatcgg ttaccaagcc caagttatcc cagccttgct tgcaggtttg
    22261 agtctgtctt atcttgaaat cttctggcgc aagcatatcc cagaagtcat ttctatgatt
    22321 tttgtacctt tcttgtcatt gattccagcc ttgattttgg ctcatactgt tttgggacca
    22381 atcggttgga caattggaca aggactttca tcagttgtct tggcaggttt aactggtcca
    22441 gttaaagggc tcttcggtgc aatttttggt gccctctacg ctccatttgt catcacaggt
    22501 ctgcaccata tgaccaatgc cattgataca caattgattg cggatgctgg tggcactgcc
    22561 ctatggccaa tgattgctct ttctaatatt gctcaaggct cagccgtgtt tgcctattat
    22621 ttcatgcatc gccatgatga gcgtgaggct caggtttcac ttcctgcaac catttcagcc
    22681 tatctcggtg ttacagaacc agctcttttt ggggttaacg taaaatatat ttatccattt
    22741 gttgctggga tgactggttc agcccttgca ggcatgttat ccgttacttt taatgtaact
    22801 gcggcttcta ttggtatcgg tggtttgcca ggtattctct ctattcaacc tcaatacatg
    22861 ctgccatttg caggaactat gctagttgcg attgttgttc caatgctctt gactttcttc
    22921 tttcgcaagg ctggtctctt cacaaaaata gagggcgata cgaacttgca ggcagaattc
    22981 gttgctcaag aagaagcaga atttgtgaac catgaaccag tagaacttac ttcggtagaa
    23041 attatcagcc cactaactgg ccaagtgaaa gaattgagtc aagcgacgga tcctgttttt
    23101 gcatcaggtg tcatggggca aggtctggtc attgaaccaa gccaaggtga gttgacctct
    23161 ccagttaatg gaacagtgac ggttcttttc cctaccaagc atgccatcgg cattgtctct
    23221 gacgagggag ttgaattgct catccacatc ggtatggata cagtaggtct tgatggcaaa
    23281 ggttttgaaa gtcttgtagt ccaaggagat cacgttatag ttggccagca actgattcgt
    23341 tttgatatgg atgtcattaa ggctgcaggt ctggtgacag aaactcctgt tatcatcacc
    23401 aaccaagatg cttatacagc gactattact ggaacttatc cgacaacgat ccaagctgga
    23461 gcatctctca tggtcgctac acgaatctaa tactcttcga aaatctcttc aaaccacgtc
    23521 agctctatct gcaacctcaa aatagtgttt tgagcaacct gtggctagct tcctagtttg
    23581 ttctttgatt ttcattgagt ataattgaaa tagcacaaat agggacggaa gactgcttcc
    23641 tcccttttat cagaaaagga gaaacagatg acacttgata aaggaaaagt agtctatcaa
    23701 atctatccaa aatcttacaa agacaccact gaaaacggta ttggggattt ccgtgggatt
    23761 atcgaaaaaa ttccctattt agccaaacta ggtgtggata tggtctggct caatccattc
    23821 tatccaagcc ctcaacggga taatggttac gatatttcag attatatggc agtggatcct
    23881 ctttttggtg atatggctga ttttgaggaa atggtgtgta tcggtaaaga gcacaagatt
    23941 gactttatgc tggacatggt acttaatcat tgttcgacag agcatgaatg gtttcagaaa
    24001 gccctagctg gtgataagta ttatcaagac tttttcttca tccaagacca accaacagat
    24061 tggcagtcta agtttggtgg ttctgcatgg gcgcctttcg gggatactgg gaaatactat
    24121 cttcacctat ttgatgagac ccaggctgac cttaactggc gcaatcccaa tgtccgtaag
    24181 gagcttttca aggttgttaa tttctggcgc gacaagggtg tcaaaggttt tcgatttgat
    24241 gtgatcaatt tgattggtaa ggacgaggtt tcagtggact gtcctgaaaa tgaagggaag
    24301 ccagcttata cagacaaacc catcgttcat aactatttgc gtatgatgaa ccaagccact
    24361 tttggatctg acgatagctt tatgacagtt ggggaaatgt cttctaccac catggaaaac
    24421 tgtgtcctct attcgtcgcc tgatcgtcag gaattatcca tgacctttaa ttttcatcac
    24481 ctcaaggtgg actataagga tggacaaaag tggaccttgg ctccctttga ttttgaagag
    24541 ttgaagagtc tttaccatag ttggggtaag gaaatgagtg ataaagacgg ttggagtgcc
    24601 ctcttttgga acaatcacga tcaaccacgt gccttgaacc gttttgtcga tattcaaaac
    24661 ttccgcaagg aaggagccac catgctagca gccagcattc acctgtcacg tgggacacct
    24721 tatatctaca tgggtgagga aatcgggatg attgacccag actatgattc tatggctgat
    24781 tatgtggatg tcgaatcgct taatgcctat cagatgctct tagaagaagg aaagagtcag
    24841 caagaagcct tccagattat tcaagctaag tcgcgtgata attcacgcat tcccatgcag
    24901 tgggatgctt cggaaaatgc aggattttca acaggcactc cttggttgaa agctggtaaa
    24961 tcctataaat acatcaatgt agaaaatgaa atccagggtc cgatttttac cttctatcaa
    25021 gacttgattc gactgcgtaa ggaaatgcca atcatttcag aaggaagtta caaaccagcc
    25081 tttgaagata gcaaacaagt ctacgctttt gaacgccagt ttgaggatca aaagttacta
    25141 gtgctcaata acttttatgc taaagaagtg gaaatcgact tgccagcagt ctaccaaaat
    25201 ggacagattt tgatatcaaa ctatgaagat gcagaagtgt ctgagaaaat tctactcaaa
    25261 ccctatcaaa cactggctat ttatgtaaat taatactctt cgaaaatctc ttcaaaccgt
    25321 gtcagtttta tctgcaacct caaagcggtg ctttgagcaa cctgtggcta gcttcctagt
    25381 ttgctctttg attttcattg agtataaact tagcaaggag acctcttttt cagaaaagca
    25441 gggttctttt tgctgtctat tccatccctg aaagtgtaga acaaactggt cagggtggct
    25501 agtttgtggt ataatgaaag ggactcaaaa agaaacagga gaaaaatgat ggatttactt
    25561 ttagcaattg tattgattgt gctagctttt ctaggaggag ctcttggagg aatgtacttg
    25621 gttcgtaagc aaatcgaaaa agaatttgct gacaacccac gtttgaatgc tgaagcagtt
    25681 cgtactcttt tgagtgcaaa tggtcaaaaa ccaagcgaag ctaaggtaca acaagtttac
    25741 caccaaatca tccgccaaca aaaggcagcc cttgctaaca ataaaaagaa aaaataaata
    25801 aggaaaagtc tgggatgaaa gttccagact tctcactatg ttggttatgg tttagggatg
    25861 agactttttc cttgcattct attgatattt gattatgatt aagagagagg tagttgacat
    25921 tctatcaagc tgtcggtcag ttcgttcagt acaaggaatc ataatgaacg atcaatcaga
    25981 aaaaagacta gaaagaagac tgtatggata atcgaccaat tggttttttg gattcgggtg
    26041 tcgggggctt gaccgttgtg cgcgagctca tgcgccagct tccccatgaa gaaatcgtct
    26101 atattggaga ttcggcgcgg gcgccctatg gcccccgtcc tgctgagcaa attcgtgaat
    26161 atacttggca gctggtcaac tttctcttga ctaaggatgt caaaatgatt gtcattgctt
    26221 gtaacactgc gactgcggtc gtctgggaaa aaatcaaggc tcaactagat attcctgtct
    26281 tgggtgtaat tttgccagga gcttcggcag ccatcaagtc cagtcaaggt gggaaaatcg
    26341 gagtgattgg aacgcccatg acggtacaat cagacatata ccgtcagaaa atccatgatc
    26401 tggatcccga cttacaggtg gagagcttgg cctgtcccaa gtttgctccc ttggttgagt
    26461 caggtgccct gtcaaccagt gttaccaaga aggtggtcta tgaaaccctg cgtcccttgg
    26521 ttggaaaggt ggatagcctg attttgggct gtactcatta tccactcctt cgccctatta
    26581 tccaaaatgt gatggggcca aaggttcagc tcatcgatag tggggcagag tgcgtacggg
    26641 atatctcagt cttactcaat tattttgaaa tcaatcgtgg tcgcgatgct ggaccactcc
    26701 atcaccgttt ttacacaaca gccagtagcc aaagttttgc acaaattggt gaagaatggc
    26761 tggaaaaaga gattcatgtg gagcatgtag aattatgaca aataaaattt atgaatataa
    26821 ggatgaccag gactggtatg ttgggtctta tagtattttt ggtggcgtta acagtttgag
    26881 cgactatcag acagattttc ctctgtttga attctccaaa atatttggag atgaagagta
    26941 tggtttcccg ctttcagtta ctgttttacg ctatggttct acctaccgtt tgttctcctt
    27001 tgtggtagat atgcttaatc aagaaatggg acgaaacttg gaagttattc aacgtcatgg
    27061 ggccctgctc ttggttgaaa atgggcaact cttgtatgta gaattgccta aagaaggggt
    27121 caatgttcat gatttctttg agacaagcaa ggtcagagaa accttgttga ttgcgactcg
    27181 taacgaaggc aaaaccaagg aattccgagc tatctttgat aagttaggct acgatgtgga
    27241 aaatcttaat gactaccctg acctgcctga agtagcagaa acaggtatga cctttgaaga
    27301 aaatgcccgc cttaaggcag aaaccatttc tcaattaacg ggtaagatgg ttttggcaga
    27361 tgattctggt ctcaaagtcg atgtccttgg tggcttacca ggcgtctggt cagctcgttt
    27421 cgcaggtgtg ggagcaactg accgtgaaaa taatgccaaa ctcttgcacg aattggccat
    27481 ggtctttgaa ctcaaggacc gctcggctca gttccacaca accctagtcg tagccagccc
    27541 aaataaggaa agtttagttg ttgaagcaga ctggtcaggt tatattaact ttgaacctaa
    27601 gggtgaaaat ggctttggct atgatcccct cttccttgta ggagagacag gtgagtcatc
    27661 agctgaatta accctagaag aaaaaaatag tcaatctcac cgtgccttag ccgttaagaa
    27721 acttttggag gtatttccat catggcaaag caaaccatca ttgtaatgag cgattcccat
    27781 ggcgatagct tgattgtgga agaagtccgt gatcgctatg tgggcaaagt cgatgccgtt
    27841 tttcataacg gcgattctga actacgtccg gattctccac tttgggaggg catccgcgtt
    27901 gttaaaggga acatggactt ctacgccggc tacccagaac gtctggtgac tgagcttggt
    27961 tcgaccaaga ttatccaaac tcatggtcac ttgtttgaca tcaatttcaa ctttcaaaag
    28021 ttggactact gggctcagga ggaagaggcc gctatctgcc tctatggtca cttgcatgtg
    28081 ccaagtgctt ggttggaagg caagatcctc tttctaaatc caggttctat cagtcaacca
    28141 cgaggtacca tcagagaatg tctctatgct cgtgtggaga ttgatgatag ttacttcaaa
    28201 gtggactttt tgacacgaga tcacgaggtg tatccaggtt tgtccaagga gtttagccga
    28261 tgattgccaa ggagtttgag actttcttgt tggggcagga ggaaactttt ttgacccctg
    28321 ctaaaaatct agctgtgttg attgataccc acaatgcgga tcatgcgacc ctcttgctca
    28381 gtcagatgac ctatacccgt gttcccgttg tgacagatga aaaacagttt gttgggacga
    28441 ttggactcag agatattatg gcttatcaga tggagcatga cttgagccaa gaaatcatgg
    28501 cggatacgga tatcgttcat atgacaaaaa cggacgtagc ggttgtttcg cctgatttca
    28561 ccattacgga ggtcttgcac aagctagtag atgagtcctt cttaccggtt gtggatgcag
    28621 agggtatttt ccaagggatt attacgcgca agtccatcct caaggccgtt aatgccctct
    28681 tgcatgactt tagtaaggaa tatgagattc gatgccaatg agagacagga tttcagcctt
    28741 tttagaggaa aagcagggct tgtctgtcaa ttccaaacag tcctataagt atgatttgga
    28801 gcaattttta gacatggtag gtgagcggat ttctgagacc agtctcaaga tttaccaagc
    28861 ccagctagcc aatctaaaaa tcagcgccca gaagcgaaag atttcggcct gtaaccaatt
    28921 tctatacttt ctctatcaaa aaggagaggt ggacagcttt taccgcttgg aattagccaa
    28981 acaagctgaa aagaagacgg aaaagccaga gattctatac ctagactctt tttggcagga
    29041 aagcgaccat ccagagggcc gcttgctagc gctcttaatc ctagaaatgg ggctcttgcc
    29101 cagtgagatt ttagccatca aggttgcgga catcaatctg gattttcagg tgttgcgaat
    29161 cagcaaggct tcccaacaga ggattgtcac cattcccacg gccttgcttt cagaattgga
    29221 acccttgatg gggcagacct atctttttga aagaggagag aaaccctatt ctcgtcagtg
    29281 ggcctttcgt cagttagaat cttttgtcaa ggagaaaggt tttccatcct tatcagctca
    29341 agtcttacgt gaacagttta ttctaagaca aatagaaaac aaggtcgatt tgtacgaaat
    29401 tgcaaaaaaa ttaggattaa aaacagtcct gaccttagaa aaatatagat aatggatatt
    29461 aaattaaaag attttgaagg acccctggac ttgctcttgc atctggtttc taagtaccag
    29521 atggatatct acgatgtgcc cattacggaa gtcatcgaac agtatctagc ctatgtctca
    29581 accctgcagg ccatgcgtct ggaagtgacg ggtgagtaca tggtcatggc tagtcagctc
    29641 atgctgatta agagtcgtaa actccttccg aaggtagcag aagtgacaga cttgggggat
    29701 gatctggagc aggacctcct ctctcaaatc gaagaatatc gcaagttcaa gctcttgggt
    29761 gagcacttgg aagccaagca ccaagaacgg gcccagtatt attccaaagc gccgacagag
    29821 ttgatttacg aagatgcgga gcttgtgcat gacaagacga ccattgacct ctttttggct
    29881 ttttcaaata tcctagccaa gaaaaaagag gagtttgcac aaaatcacac gactatcttg
    29941 cgggatgagt ataagattga ggacatgatg attattgtga aagaatcctt gattggacga
    30001 gatcaattgc gcttgcagga tttgttcaag gaagcccaga atgtccaaga ggtcatcacc
    30061 ctctttttgg caaccctaga gttaatcaaa acccaggagc tgatcctcgt gcaagaggag
    30121 agttttggag atatctatct catggaaaag aaggaagaaa gtcaagtgcc tcaaagctag
    30181 acttgataga gaggaaagat gagtacttta gcaaaaatag aagcgctctt gtttgtagcg
    30241 ggtgaagatg ggattcgggt ccgccagtta gctgaactcc tctctctgcc accgacaggc
    30301 atccagcaaa gtttaggaaa attagcccag aagtatgaaa aggacccaga ttccagtttg
    30361 gctttgattg agacaagtgg tgcttataga ttggtgacca agcctcaatt tgcagagatt
    30421 ttgaaggaat actctaaggc gcctatcaac cagagcttgt ctcgggctgc ccttgagacc
    30481 ttgtccatta ttgcctacaa acagccgatt acgcggatag aaattgatgc catccgtgga
    30541 gttaactcga gtggagcctt ggcaaagttg caggcttttg acctgataaa ggaagacggg
    30601 aaaaaggaag tattggggcg ccccaacctc tatgtgacta cggattattt cctagattac
    30661 atggggataa accatttaga agaattacca gtgattgatg agcttgagat tcaagcccaa
    30721 gaaagccaat tatttggtga aaggatagaa gaagatgaga atcaataagt atattgccca
    30781 cgcaggtgtg gccagtagga gaaaagcaga agagctgatc aagcaaggtt tggtgacggt
    30841 taacggccaa gtggtgcgtg aactagcaac cactatcaag tcaggtgaca aggtcgaagt
    30901 tgaaggtcaa cctatctaca acgaagaaaa ggtctattat ctgcttaaca aaccacgcgg
    30961 tgtcatttcc agtgtgacag atgataaggg tcgcaagacg gttgtcgacc tcttgcccaa
    31021 tgtcaaagag cgtatttacc ctgtgggtcg tttggactgg gatacatcag gagtcttgat
    31081 tttgaccaat gatggggact ttacagacga gatgattcac cctcgtaatg agattgacaa
    31141 ggtttatgtc gcgcgtgtta aaggtgtggc caataaggac aatcttcgcc ccttgacccg
    31201 tggtcttgag attgatggta agaaaaccaa gccagctgtt tatgaaattc tcaaagtgga
    31261 cccagtcaaa aatcgctctg tggtgcagtt gaccatccat gaagggcgta accatcaggt
    31321 taaaaagatg tttgaagctg ttggtctcca agtagataag ttgtctcgga ctcgtttcgg
    31381 acacctagac ttgacaggac tccgtccagg agaatcccgt cgtcttaata aaaaagaaat
    31441 cagccaacta cacaccatgg ctgtaactaa gaaataatga aacgaatttt aatagcgcct
    31501 gtgcgctttt accaacgttt tatctcacca gtctttccac cctcttgtcg ctttgagctg
    31561 acttgttcca actacatgat tcaggctatt gaaaaacatg gttttaaggg ggtattgatg
    31621 ggcttggctc ggattttacg ttgtcatccc tggtcgaaaa caggtaagga ccccgttcca
    31681 gaccactttt cccttaaacg aaatcaagaa ggggaatgag gtggggtaaa tagatttcaa
    31741 aatgataaaa acgcatccta tcaggtttga gtaaacttga taggatgcgt tttagaatgt
    31801 caaaatttta tactcttcga aaatctcttc aaaccgcgtc agctttcatc tgcaacctca
    31861 aaacagtgtt ttgagcaacc tgcggctagt ttcctagttt gctctttgat tttcattgag
    31921 tattaaattg agtttgaagt ggcttatttc aaagcttttt gtatgtcttc aatcatgagt
    31981 tttgttgatt caagtccgcc tccgcttaga taccagaggt ctggtgttag ttggataatc
    32041 ttaccatttt tagcagcagg tgtttcagcg ataagggcat tttctaggac accgtcgttg
    32101 ctagagttgt ccccaccgat ggcaagggta cggttgatga caaagaggat gtcagggttg
    32161 atttctttga cactttcaaa gctgacttct tgtccgtggc gtgagtcttc aaattttgta
    32221 tcagttggtt tgaatttcaa ggtttggtac aagaaagaga aacgagattt ggcaccaaag
    32281 gctgccattt ttccttcatt aaggaggatc gcaagggctt ttttgtcaga gctttcattt
    32341 ttagtagcga cttcttggat gctcttgtct agcttggcca attcttcctt ggctttctgt
    32401 gtaccagttt cgccgaaggc acttgctaag gattcgatat tagccttggt agaagtccag
    32461 tagtcgtcct tgcttgcttg gaagagaacg gttggggcga tttctttgaa tttgtctacg
    32521 aatttttgtg tacgtggtga agcgataatc aaatcaggct caagggcggc gatagcttct
    32581 aaatcaggtt ctttcataga accaacattt ttgacagttc ccactaggtc ttttagataa
    32641 gtcggaacag tttttgtagg cattccgacg atattttttt caaatcctaa agcgcgaata
    32701 gtatccgcag cgccgaggtc aaaggtcaca atcttttcag gaactttgga aagtttgacc
    32761 tcggccagtg aacttttaat ggttacctct gttggagcag agctactggt ctctgtctga
    32821 ctagtgcttg agtttgtact acatgcacca agtaggagca agaagctggc cactagggca
    32881 gtgaaataaa gtttaaggga tgttttcata atttctcctc tttaaaatgt gataacgatt
    32941 tagggagtct cttgatctta ttgactaaga gactgaaggt tctctaactt gagcttttat
    33001 gttactagct atagatacag atctttttgt cattgatatc agctagcgtg atgggaatct
    33061 cataaagttg actgagcagg tcagcctgca tgatttgatc ggttcttccc ttgctaaaga
    33121 cctggccgtc cttgaaggcg acaatttcat ctgcatactg actggctatg ttgatatcgt
    33181 ggaggacgat gataatggtc ttgccgagtt cctccaccag tcgtcgaaga atctgcatca
    33241 tgctgacgct ttgcttgata tcgagattgt tgagtggttc gtccagcaag ataaagtccg
    33301 tatcctgggc cagtaccata gcgataaaga cgcgctggag ttgcccccct gacaggctat
    33361 tgatgtagcg gtcttttaag ttggtcagtt ccaaatagtt cagagtttct cggatttttt
    33421 cccagtcttc tgatctaagt cgacctcggc tgtagggaaa acgtccaaaa ctgaccagtt
    33481 cttcaacagt caatttggct tggtaattga ttttctgttt taggatggtt agttcttggg
    33541 ccagttcttg cgaattccag ctctcgattt cacgtccttt gatactgaga actccctgat
    33601 ctttcttggt tagtctgctc atgatggaga ggagagtcga ttttccagca ccatttggac
    33661 caataaaggc tgtcagtttt tgaggactga cttcaagcga aatgccttgc aaaatatcct
    33721 gtttttgaat ggatttgtca atgttttcca gtttcactga cgagccctcc tatatagtaa
    33781 gataaagaat aagaagccac ccacactctc aatgatcata ctgatacgaa tttccagtgc
    33841 aaagactcgt tcaatcaagg cttgccccaa ggttaagcta ataaatccaa ccagaatggc
    33901 cactataaag agtaacttgt gctgatagtc tttgacaatc aggtaggtga ggttggccag
    33961 cataaagccg aagaaggcca taggtcctac caaggcagtg gccgttgagg tcaaaagcac
    34021 gattccccag aggagctctt tctgttcttt ttcaacatcg agtcccaata tctgagccgt
    34081 ttctctttgc aggtgcaaga catctagaac gactgctttt cgaaagaaaa agattgtcaa
    34141 agcgaggatg atcagagaac cgatggctag gatggaagtg ttgagatgtt gaaaggaggc
    34201 aaaaagacta ttttgcagtt tatcgtattc gtttggatcc attaggactt gaaggaaggt
    34261 gctgatattt cgaaagagac ttctgagcgc tagacagatc agcaggatga agaccaggtc
    34321 ttgcttcatc agtgtcttca agtaaccttg taaggcgaga aagaagaggg actggacaag
    34381 aagtaagact aggaattcta agatagggga tttgccaagt tgaagaaact tgctttcaaa
    34441 aaccagtagt agggtttgta gtaggacgta gaaggattca attcccaaaa tactaggcgt
    34501 caggaagcga ttttccgtca gggtttgaaa actaatggtc gaaatcccag tcgcgatggc
    34561 taccaagaga taaacgatga tcttttggga acgcaacttc caagcaaagg ctgacaagtg
    34621 agtgatgggc caaaagtaga gaagacaagc tccgatggca agaataatga gaatccagaa
    34681 gagcttggta tgtttgcttt tagtctgcat cttttcgtcc ccctctccag agaagtagga
    34741 taaagacgag actaccgatg attcctagca agagactgac agacaactca tagggcctaa
    34801 tcagaactcg ggataggata tcgcaagcca gaactagatt ggcaccaacc agtgcgacca
    34861 tgagtttggt ttgacttaga ttatctccat agcgcttgcg aacaagattg ggaacgataa
    34921 ctccgagaaa tggtaggcca cccacggtaa tcatggtgac gcttgtcgtt agcgccacca
    34981 gaaagagggc cagtttttca agtagggagt aggaaatccc caaactctcg ctggtttctt
    35041 tccctagatt catgatggtg aaggtttggg ataatttcca aacggttatc aggatgatga
    35101 ggcctaagaa gagccactca tactgatggg tctgaatcat ggagaaggag ccctgggtcc
    35161 aggcagtcat actctgaacc agattgaaac gataggcgat aacttctgtg actgagccga
    35221 taatcccgct atagatgatc ccaatcagag gcaacatcca cctttccttt acagtaaaaa
    35281 tggtcataaa ggctaggaag aagagggtga atacgatgga tgaaacaaaa gcgaagagca
    35341 tcttttgggt cagactagcc gatggaaaga caaaaaggct cagcaccatt cccagtttgg
    35401 cggcttcagt cgttccaact gtactcggtg cagcaaactg attttgggta atagtctgca
    35461 tgagaaggcc tgccatactc atactagagg cagtcaggag aatactgata gttcttggga
    35521 gacgggactc ttgaaagagg agccaggtct gctggtcgaa atcaaatagc tttccccatg
    35581 aaaaatcact ggtcccaatg ctaatagaga gaaagactag gagtagaagt aagccaatta
    35641 aataatgaga aagtttcata ccccgtcctt tcatgtagat ttggtatcga aagatatctg
    35701 cggatataaa tgtaacatta tttttctaat ctgtcaataa aatttctgac aatttaataa
    35761 atacaacaag gagagagcaa caagactttc tcctttgtta tcctattcta aaatgttttt
    35821 accttaatct gataaaataa tatcttcgag ggagtagcta gccgtccaat caagatattg
    35881 tttagctttt gaagcatctg ctaggacact ggctgggtca ctagcacgtc gagcaacaat
    35941 ctcgtgtggg attttttaat ttagtaattc ttcagcagtt ttaaagattt ctttgatagt
    36001 atagcctttt ttagttccta agttaaagat ttgagaagaa ctgtcttctt gaaataggta
    36061 gttcattcct ttaacatgag cctatgcaag gtccaagaca taaatgtaat ctcgaataca
    36121 tgaaccgtca cgtgtatcgt agtcatctcc aaatattttt aagctatcat tttgtcccaa
    36181 tgcggtcttg ttgatatttg gaatgatgtg agttggattt ttcacacgca gaccgtttga
    36241 agcatccatt tcagccccag caacattaaa gtaacggaaa ataacatatt tccagtcgta
    36301 gcgattggcc atccagtaaa tcattcgttc gcccatcagt tttgtctctg cataagggtt
    36361 gacagggtcg agcagggtat cttcagtcac cggcttgtca atacagttat ttccatagag
    36421 agaagcagtc gaagagaaca tgattttttg aatgccaact tcagataaga ctttgagaac
    36481 ttggttcata ccagcaacgt tggcagtgaa gtatttactt ggattttcaa tactttcgct
    36541 cacaacaatt tcacctgcac aatggaggac agcatcaatc tgattttctt ctaagtaagc
    36601 ctttaaggcg ctagcatcat aaacatccag ttctttaaag ctagcacgac tatccacagc
    36661 cgctcgattt cctgtggaga gattatcgag gacatgcacc ttatagccag catttaaaag
    36721 agctttaacg gtatgggagc caatgtagct agtcccacct gtaacaagaa ttgttttggt
    36781 catgattttt tccttttcta gttttgtact atagtaaatt gaaataagat atgaacaact
    36841 ctattaggaa agtcaaatta atttctagaa atgtttcagc agctacagcg tactattcca
    36901 aactcaacca actatatatt taaagaaaga agaaagggaa gtcaactatt ttctgtaaat
    36961 ttcatgaaaa atccaaacaa ctttgatggt gtattgtttt tttgtttgga aataaatatt
    37021 cgagttaatt ttggaatgtt tactagattt tgcactacat gcaagagaat actatccttt
    37081 tctaagatag agcaggacta agatactaac ttagaaatcc accttcccac tatccttctc
    37141 ctataaaaag tggtaaaatg gatgaaagaa agaaggaact gaaatgacaa cattattttc
    37201 aaaaattaaa gaagtaacag aacttgctgc agtctcaggt catgaagcgc ctgtccgtgc
    37261 ttatcttcgt gaaaagttga caccgcatgt ggatgaagtg gtgacagatg gcttgggtgg
    37321 tatttttggt atcaaacatt cagaagctgt ggatgcaccg cgcgtcttgg tcgcttctca
    37381 tatggacgaa gttggtttta tggtcagcga aatcaagcca gatggtacct tccgtgtcgt
    37441 agaaatcggt ggctggaacc ccatggtggt tagcagccaa cgtttcaaac tcttgactcg
    37501 tgatggtcat gaaattcctg tgatttcagg ttctgttcct ccgcatttga ctcgtggaaa
    37561 ggggggacca accatgccag ccattgccga tatcgttttt gatggtggtt ttgcggacaa
    37621 ggctgaggca gaaagttttg gcatccgtcc tggtgatacc atcgtaccag atagttctgc
    37681 aattttgaca gccaatgaaa aaaatatcat ctcaaaagct tgggataacc gctacggtgt
    37741 cctcatggta agcgagctag ctgaagcttt atcaggtcaa aaactcggca atgaactcta
    37801 tctgggttct aacgtccaag aagaagttgg tctgcgtggc gctcatacct ctacaaccaa
    37861 gtttgaccca gaagtcttcc tcgcagttga ttgctcacca gcaggtgatg tctacggtgg
    37921 tcaaggcaag attggagatg gaaccttgat tcgtttctat gatccaggtc acttgcttct
    37981 cccagggatg aaggatttcc ttttgacaac ggctgaagaa gctggtatca agtaccaata
    38041 ctactgtggt aaaggcggaa cagatgcagg tgcagctcat ctgaaaaatg gtggtgtccc
    38101 atcaacaact atcggtgtct gcgctcgtta tatccattct caccaaaccc tctatgcaat
    38161 ggatgacttc ctagaagcgc aagctttctt acaagccttg gtgaagaaat tggatcgttc
    38221 aacggttgat ttgattaaac attattaaac cataagggag gtggtaggga tggtagaacc
    38281 aaacctagaa agccttataa aagatcttta caatcatgct cgacatgatt tgagtgaaga
    38341 tttagttgct gctctcctag agactactaa aaaactgcct actacaaatg agcaattgca
    38401 ggcagttcgt ctctcaagcc tggtcaatcg tgaattgctc ctaaatccca aacatccagc
    38461 acctgagttg ctcaacttgg ctcgctttgt caaaagagaa gaagccaagt acagaggaac
    38521 tgcgacttct gcgcttatgt atgaggaact ttttaaaatg ctttgattcc attgtggatc
    38581 aaagcatttt ttataagacc tatctcgtga gcgttcaaat agtagtaaca aggaatcatg
    38641 agaagtcagc cgagaccata gtagtgaaga aacttctgta atggaagtgg agtgaagtga
    38701 ggaatcgtca aacggtaggg gataggctgt ttgaagggtg ctacgaaaaa gatagggtaa
    38761 ggtgaaatta tagcggaatg aaataagata tgaacaaatt gattagggaa atcaaatgaa
    38821 tttatagaaa tcttttagca gtcatggcgt cctattctag tttcaaaatg ctataaatac
    38881 gaacaaattg attgggaaat tcaaatcgct ttctatcaat gttttagaag atacagtgcc
    38941 ctagtccaac ttcaatatac tataaaagaa cagatggaag caattatgat ttacttctat
    39001 ctttaaaata aatgatctga taggaaaaat gtgtcccctc ataaaaaata ggatagtacg
    39061 gatggaaggc ttttgtagac tggaggacga aggagtttag aaactctcgt taaaagttag
    39121 ttgagccgga gtatggtggt gtggataatt atcaaaaatt atttctaaat cgaaatagtt
    39181 gacagttaga acgatgagtg ttacaattgt tttattcatt tcgatatcga aataaattgg
    39241 aggtgttatg aaagatggtc atttgctagc ccatcatatt cgtttgttga atgggcggat
    39301 ttttcaaaag ttactgagtc aagatcctga ggctctttat aggggtgaac agggcaagat
    39361 tttagcggtt ttatggaata gtgaaactgg ctgcgcaact gcgacagata tcgcgcttgc
    39421 gactgggctt gcgaataata cgctaacgac tatgataaaa aagctagagg aacaaaagct
    39481 tgtaattgtt agtccgtgtg gaaaagacaa gcgtaagaag tatttagttt taacggagtt
    39541 aggcaagtcc cagaaagaag tggggcatcg tgtcagtcag aaattggata ctatctttta
    39601 caaaggattt tcagaggaag aaattcacca atttgaaggt tttcaagaaa gaattttggc
    39661 gaatttgaaa gagaagggaa atgaggttta gaatatgtca caacaagtga aaaatgctca
    39721 caacctatac atccatgcca ttcaagacgg acgagttgct gaggctcaag cccagtctgt
    39781 aggggatacc tatatccaac attcgacagg tgttcctgac gggaaagaag gatttgcagc
    39841 cttctttgca gatttctttg agcgtcatcc agagcgtcag attaagattg tccgcaccat
    39901 tgaggatggc aatctggtct ttgttcatgt tcatcaatat ctgaatggtg gagaagctca
    39961 atgggtgacg acggatactt tccgtgcgga tgagaatggt cgtattgttg agcattggga
    40021 tgtcattgac tactatcgaa cacctgaaaa tgatcaacta gatcaaattt ttggagattt
    40081 tgaaatcaag gatttggaca agaaagcaga aaataaaaaa ctggttcgcc gtttcttgac
    40141 agaaattttc caaaatgggg agctagagca gtggagtgat tatgtggcag acgatttgat
    40201 tcagcataat catgagattg gacaaggaag tgctgcttat aaaaactatg tggctgaata
    40261 tagtgtcact tttgactttg ttttccaact cttaggacaa ggaaactatg tggttagcta
    40321 tggtcagact cagattgatg gcgttgctta tgcccagtac gatatcttcc gtttagagaa
    40381 cgggaaaatt gtggagcatt gggataataa ggaagtcatg cctaaggtag aagacttgac
    40441 taatcgaggg aagttttaaa ttgaggacaa agaatgattg aatacaaaaa tgtagcactg
    40501 cgctacacag aaaaggatgt cttgagagat gtcaacttac agattgagga tggggaattt
    40561 atggttttag tagggccttc tgggtcaggt aagacgacca tgctcaagat gattaaccgt
    40621 cttttggaac caactgatgg aaatatttat atggatggga agcgcatcaa agactatgat
    40681 gagcgtgaac ttcgtctttc tactggttat gttttacagg ctattgctct ttttccaaat
    40741 ctaacagttg cggaaaatat tgctctcatt cctgaaatga aggggtggag caaggaagaa
    40801 attacgaaga aaacagaaga gcttttggct aaggttggtt taccagtagc cgagtatggg
    40861 catcgcttac ctagtgaatt atctggtgga gaacagcaac gggtcggtat tgtccgagct
    40921 atgattggtc agcccaagat tttcctcatg gatgaaccct tttcggcctt ggatgctatt
    40981 tcgagaaaac agttgcaggt tctgacaaaa gaattgcata aagagtttgg gatgacaacg
    41041 atttttgtaa cccatgatac ggatgaagcc ttgaagttgg cggaccgtat tgctgtcttg
    41101 caggatggag aaattcgcca ggtagcgaat cccgagacaa ttttaaaagt gcctgcaaca
    41161 gactttgtag cagacttgtt tggaggtagt gttcatgact aatttaattg caacttttca
    41221 ggatcgtttt agtgattggt tgacagctct atctcaacat ttgcagttgt cacttttgac
    41281 cttgttacta gctattttgc ttgcgattcc cttggctgtt tttcttcgct atcatgagaa
    41341 gctggccgac tgggtcttgc agattgcagg tattttccag accatcccgt ctctggcctt
    41401 gttggggctc tttatccctt tgatgggaat tgggaccttg ccggctttga cagctctagt
    41461 gatttatgcg atttttccga ttttacaaaa tactattact gggctgaagg gaattgatcc
    41521 gagtcttcaa gaggctggga ttgcctttgg gatgaccaga tgggagcgtc tcaagaagtt
    41581 tgaaattcca cttgccatgc ctgttatcat gtctggaatt cggacggcag cggtcttgat
    41641 tatcggtacg gctaccttgg cgaccttgat tggggcaggg ggactgggtt cctttatcct
    41701 gttgggaatt gaccgtaata atgccagttt gattttgatt ggggcccttt cttctgcagt
    41761 gctagctatt gcctttaact tcctactaaa agtaatggaa aaagcgaaat tgcggacgat
    41821 tttctctggt tttgccttgg tggctttatt actgggtctg tcttatagtc cagccctttt
    41881 ggctcaaaaa gagaaggaaa acttgattat tgctgggaaa ataggcccag aaccagaaat
    41941 tttggctaat atgtataaat tgctgattga agaaaatacc agcatgactg cgactgttaa
    42001 accgaatttt gggacgacaa gtttccttta tgaagctctg aaaaaaggtg atattgacat
    42061 ttatcctgaa tttaccggta cggtgactga aagtttgctt caaccatcac ccaaggtgag
    42121 tcatgagcca gagcaggttt atcaagtggc gcgtgatggc attgccaagc aggatcatct
    42181 agcctatctc aaacctatgt cttatcaaaa tacctatgct gtagctgttc cgaaaaagat
    42241 tgctcaagaa tatggcttga agaccatttc ggatttgaaa aaagtggaag ggcagctgaa
    42301 ggcaggcttt acgcttgagt ttaacgaccg tgaagatgga aataagggct tgcaatcaat
    42361 gtatggtctc aatctcaatg tggcgactat gcagccagct cttcgttatc aggcaattca
    42421 gtcaggggat attcaaatca cggatgccta ttcgactgat gcggaattgg agcgttatga
    42481 tttacaggtc ttggaagatg acaagcaact cttcccacct tatcaagggg ctccactcat
    42541 gaaagaagct cttctcaaga aacacccaga gttggaaaga gttcttaata cattggctgg
    42601 taagattaca gaaagccaga tgagccagct caactaccaa gtcggtgttg aaggcaagtc
    42661 agcaaagcaa gtagccaagg agtttctcca agaacaaggt ttgttgaaga aatgatggga
    42721 cagagacttt aaacatactg aactcaactt ccttaaacga ctagataaaa gaatgctcag
    42781 acaatttcgt ctgggctttt ttgatgtgag aatgactgaa tgtcacttaa aatggaaaga
    42841 aagagaaaat tttcatgatt ttctaaaatt ttactgtaaa gacagttgac tattcataaa
    42901 ataggtgtat aatattttgt gaactactta acaaataaga ggtttcagct catgtcgact
    42961 aaggttagaa atcttgtgta taggcagttc attatctaat agagcgttgc gtccgaaagt
    43021 ctatccagac acggctcttt aaaaacaaaa ggagaaatga tgcatactta tttgcaaaag
    43081 aaaattgaaa atatcaaaac aaccctaggt gaaatgtcag gtggttaccg tcgtatggtt
    43141 gcggctatgg ctgatttagg attttcagga actatgaagg ctatctggga tgacctcttt
    43201 gcccatcgta gttttgccca gtggatttat ttgctggttt taggaagttt tcctctctgg
    43261 ctggagttgg tttacgaaca tcgtattgtt gactggattg ggatgatttg tagcttgaca
    43321 gggattatct gtgtaatctt tgtatcggaa ggtcgagcaa gtaattatct ttttggcttg
    43381 attaactctg ttatttacct tattttggcc ctacagaaag gcttttatgg tgaggtgctg
    43441 acgacacttt acttcacagt catgcagcca attggacttc tagtttggat ttatcaggca
    43501 cagtttaaga aggaaaagca ggagtttgtc gcgcgtaaac tggacggcaa gggctggaca
    43561 aagtatcttt ccattagtgt gctttggtgg ttggcctttg gcttcattta tcagtctatt
    43621 ggtgccaatc gtccctatcg tgattcaatc acagatgcaa ccaatggggt agggcaaatc
    43681 ctcatgacag ctgtttaccg tgaacagtgg atattctggg cggctaccaa tgtcttttca
    43741 atctatctct ggtggggaga aagcctgcaa attcaaggga aatatctaat ttatctcatt
    43801 aacagtctag ttggttggta tcaatggagc aaggcagcta agcagaatac tgatttactt
    43861 aactaggaaa agatgtttga aagtgctgtt ttgagatttc gattaaaaca gatatagttg
    43921 ataatcaagg atttatagta tgaaaaagag gatcggcggg tcctcttttg ttgttgaaaa
    43981 gataaaaaac tcagtaacct agaaataaga caactgaagc tttactctat attcaatttt
    44041 taggaatgag aaggtctaga taaaattgga caacttcctg gtctgtgaaa tcttgacctt
    44101 ttttgagcca ccaggtcaat gtctcgataa agttggacat gaccaagtgt tggaggtaag
    44161 aagtaggcag attagggtgg gcttctttta aattatcagc tagcacggaa tagacatggt
    44221 gttctagctc tttatggagt tgacggagga agtagtcatt tttggaaaat agcagactgg
    44281 tgatatggtc ttggttttta tgaaaatgga gaaagaggtg ggcgaggtag tcctcggttg
    44341 aaatggcttg ctctctttca aaaagatgat ggaagaggta gcggcagagc tggtccagaa
    44401 gaagctcctt actctcatag tgacagtaaa aggtggatcg tcccacatct gcgagatcaa
    44461 tgatatcctg aacagtagtg gcctcgtagc ccttagcatt caaaagttgt ataaaagctt
    44521 gatagatggc ttttttggtt ttgctgatac ggcggtcaat gttagtcata tggacactta
    44581 aggcaaattg ttcagaactg aataaagctg acgttttgct tctatccttt ctttgagttt
    44641 tagtggataa tgataatgaa caaggtgttc ataaatctat tataacaaag gaatgagaaa
    44701 tatgaaggca aaatatgctg tttgggtggc ttttttctta aatttgactt atgccattgt
    44761 tgagtttatt gcaggtggag tatttggttc tagcgctgtt cttgctgact ctgtgcatga
    44821 cttgggagat gcgattgcaa ttggaatatc agcttttcta gaaacaatct ccaatcgtga
    44881 agaagacaat cagtacacct tgggctataa gcggtttagc ctgctaggag ccttggtaac
    44941 agctgtgatt ctcgtaacgg gctctgttct agtcattttg gaaaatgtca cgaagatttt
    45001 gcatccgcaa ccagtcaatg atgaggggat tctctggtta ggaattattg cgattactat
    45061 caatctgtta gcgagtctgg tggttggtaa gggaaagaca aagaatgagt ctattctgag
    45121 tctgcatttt ctggaagata cgctagggtg ggtagctgtt atcctgatgg cgattgttct
    45181 tcgatttacg gactggtata tcctagatcc tcttttgtcc cttgtcattt ctttctttat
    45241 tctttcaaaa gcccttccac gtttttggtc tacactcaag attttcttgg atgctgtgcc
    45301 agaaggtctt gatatcaagc aagtaaagag tggcctggag cgattggaca atgtggccag
    45361 ccttaatcag cttaatctct ggactatgga tgctttggaa aaaaatgcca ttgtccatgt
    45421 ttgtctaaaa gaaatggaac atatggaaac ttgtaaagag tctattcgaa ttttcctaaa
    45481 agattgtggt tttcaaaata ttaccattga aattgatgct gacctagaaa ctcaccaaac
    45541 ccataagcga aaggtgtgtg acttggaacg gagttatgag catcaacatt agaaaaaagt
    45601 gaaaaatact tgggtactat cttatttgga atagagtaat ttctttatta tttaaatatt
    45661 tcaaaaattg gtaagagaag agcattgtat aaactccaga tatatgattg ttaatgataa
    45721 aaatttttcg attagataca aaatgcttga cttggagtca actcaaagtt atataataag
    45781 ataagtgagt tagaatagcg tgaattcagt gaatgaaatg agaggaggtt agcgtgtgaa
    45841 tattaaatct gccagtgatt tgttgggaat ttcagcggat acgattcggt attatgaacg
    45901 ggttggtctt gtgccaccga ttactcgtac tgctactggg attcgtgatt ttcaagatca
    45961 ggatatcgaa gcgctggaat ttattaagtg ttttcgttcg gcgggtgtct ctgtagatag
    46021 tttagttgac tatatgtcgc tctaccaaaa gggagatgaa acgagagagg agaggcttgg
    46081 tattttagaa gaggaaaagc aaaaattaga ggagcgcttg tctcagctac agacagcttt
    46141 aaatcgttta aatctcaaaa ttaaacttta taaggaagga aaattttaaa tgaaatcagc
    46201 agtatataca aaggcaggtc aggttggact tgctagcatt gaacgtccgc aaataataga
    46261 agcggatgat gtgattattc gtgtggttcg tgcgtgcgtt tgtggttcag atttatggag
    46321 gtaccgtaat ccagaaacga aagctggaca taaaaatagt ggacacgaag cgattgggat
    46381 tgttgaagaa gctggggaag ccattacgac ggtgaaacca ggtgattttg tgattgtccc
    46441 ttttacacat ggatgtggtg agtgtgatgc ctgtcttgct ggatttgacg gttcttgcga
    46501 caatcatatt ggtaataatt tggggggtga ttttcaggca gaatatattc gcttccacta
    46561 tgcaaactgg gcgctggtta aaatccctgg tcaaccttct gattatacag aagggatgct
    46621 caagtccctt ttgactcttg cagatgtcat gccgacaggc tatcatgcag cgcgtgttgc
    46681 aaatgttcaa aaaggggaca aggttgttgt tatcggtgat ggggctgttg gtcaatgtgc
    46741 tgtcatcgcg gctaagatgc gtggagcatc acaaattatc cttatgagcc gtcatgaaga
    46801 ccgtcaaaag atggctatgg agtcaggtgc gacagctgtt gttgcagaac gtggtcaaga
    46861 aggaattacc aaggtgcgtg aaatcctcgg cggaggagca gacgcagcac ttgaatgtgt
    46921 tggtacggag gctgctatag aacaggcgct aggtgttctt cataatggag ggcgtatggg
    46981 ttttgtagga gtcccacact ataataatcg tgctcttggt tcgacattta tgcaaaatat
    47041 ctctgtagca ggtggggcag cttctgctac aacatacgat aagcaatttt tactaaaagc
    47101 cgtccttgat ggtgatatca atccaggtcg cgtctttact tcaagttata aactggaaga
    47161 tatcgaccaa gcctataaag atatggatga acgtaagaca attaagtcta tgattgtaat
    47221 cgaataaaaa acgaatagga gttttagaac tctattcgtt ttttatgtta tcctattctt
    47281 gatttagggt actttctctt aatgtcagtc tggttcccag catggtcagg ctaggaattt
    47341 tgcgaccgtg gaggacttcc ttgttaagaa tatccatacc tgctcgcccc atttcttcag
    47401 tataaactgt aatactagag aggggaggat agacctgttt ggtcagactg gtgtcgttga
    47461 atgaaatgag gctgacgcga tctggcaggc tgattccagc ttcttggagg gcacggaggg
    47521 caccgatagc taaactatcg ctggctgcga aaaatgctgg cggaagttgg tctcccaagc
    47581 tctgaatggc ctccttcatt aagtcatagc cagactgggc agtaaatctt ccttgaaaga
    47641 ccagttcatc atgatagatt cccctcgctt gactgtagtt tttgaagttt tctagacgct
    47701 tgtcctgaat gatttcttct tggtctgttg tttcctcaag ccctgttaga atcccgatgc
    47761 ggtccatccc ttgactgagg aaataatcga caacctgttt catagcagtg taaaaatccg
    47821 tgataataca ggtatgtccc agggaaagtg tatcgctgtc tagaaataca agaggctttt
    47881 ggtattcttc aaaggcagaa atctgagctc ggctaaattt tccgatgcag agaatcccaa
    47941 tcacttcctc gcttagggta aaagggtggt cattaaaata gcgcaagata tcgtagtcca
    48001 actcttgggc tcttttttct attcctaggc gaatctggta gtagtagagg tcgtctagct
    48061 ccccttgttc gctgacccat tgaataatgg caatcttttg cttgggttta tgggactcgc
    48121 ctgtcttgag gtgcttggtg tagcccagct cttcagcaac ggttaaaata cggtgtctgg
    48181 tttcttctgt aacagatagg ctctggtcgc ggttgaggac acgggatacg gtcgcgatag
    48241 agacagaggc tagctgtgca atgtctttta aggtagccat aaatcctcct tgattaggtt
    48301 agtatatcat atttttcttc tttttactga tattttagta aaattttagt aaaaaggatt
    48361 gaccttggga aattccttgg atacaataga aagaaaacga ttacacgtta agatggctta
    48421 acggacagtc aaaggagaat tcatatggca caacatctta ctactgaagt ccttcgcaaa
    48481 gactttcttg ctgtttttgg tcaagaagca gaccaaacct tcttttcacc aggccgtatt
    48541 aatttgattg gtgaacacac agactacaac ggtgggcacg tttttcctgc tgctatttcc
    48601 ttgggaactt acggtgcagc tcgtaagcgt gacgaccaag tcttgcgttt ctactcagct
    48661 aactttgagg acaagggcat tatcgaagtg cctctcgctg acctcaagtt tgaaaaagag
    48721 cacaactgga ccaattatcc aaaaggggtt cttcatttct tgcaagaagc tgggcacgtg
    48781 attgacaaag gttttgattt ttatgtttat gggaatatcc caaatggtgc tggcttgtct
    48841 tcttcagcat ccttggagct cttgacagga gtcgtggcag agcatctctt tgatttaaaa
    48901 ctagaccgtt tggatttggt taaaatcgga aaacaaacag aaaacaactt tatcggagtc
    48961 aactctggta tcatggacca gtttgctatt ggtatggggg ctgaccaacg tgctatttac
    49021 ttagatacca atactttaga atacgacttg gtgccacttg atttgaagga caatgtcgtt
    49081 gttatcatga acaccaacaa acgccgtgaa ttggcggact ctaaatacaa tgaacgtcgt
    49141 gctgagtgtg aaaaagcagt ggaagaattg caagttgcct tggatattca gaccctgggt
    49201 gaattggacg agtgggccgt tgaccaatat agctatttga ttaaagatga aaatcgtttg
    49261 aaacgtgctc gccatgctgt gcttgaaaac caacgtaccc ttaaagctca agcagccctt
    49321 caagcaggtg atttggaaac atttggtcgt ttgatgaatg cgtcacacgt ttctctggag
    49381 catgattatg aagtaactgg tttggaattg gatactcttg ttcacacagc ttgggcacaa
    49441 gaaggagttc tcggtgctcg tatgacaggg gctggttttg gtggctgtgc cattgccttg
    49501 gttcaaaaag atactgttga ggcctttaag gaagctgtag gcaaacacta cgaggaagta
    49561 gttggatacg ctccaagctt ctatatcgct gaagttgcag gtggcactcg cgtccttgac
    49621 tagtcaaaag gaggctctat agtgatctta gtagataaat ttgtaacaca tgtcatttct
    49681 gaaagttcat ttgaggaaat ggatcgaatc tacctgacca accgtgtttt ggcacgagtg
    49741 ggagaaggtg ttttggaagt tgagaccaat ctggataaat tgattgacct caaggaccag
    49801 ctagttgagg aagccgttcg attagagatg attgaggata gtcagactgc gcgtgaaatc
    49861 cttggtactg aactgatgga cttggtgact ccttatccga gtcaggttaa tcgtgacttc
    49921 tgggaagcct atgtccactc tcctgagcaa gcgatagagg atttttatca actcagtcag
    49981 aaaaatgatt acatcaaact caaggccatt gctaaaaata tcgcttatcg tgttccatct
    50041 gattatggag aacttgaaat taccatcaat ctctctaagc ctgaaaagga tccgaaagag
    50101 attgcggtag ccaagttggt gcaagctagt aattatcctc agtgtcaact ttgtttagag
    50161 aatgagggtt accatggtcg ggtcaactac ccagctcgca gcaaccaccg gattatccgt
    50221 tttgaaatgg ttggtcagga atgggggttc cagtattcgc cctatgctta ctttaatgag
    50281 cattgtatct ttttagatgg ccagcatcgt cccatggcca ttagtcgtca gagttttgaa
    50341 cgtctgttgg ctatcgtaga gcagtttcca ggatattttg ctggatctaa tgccgacctg
    50401 ccgattgtgg ggggctctat tctaactcac gatcattatc agggaggccg tcacgtattt
    50461 cctatggaat tggctccctt gcaaaagacc ttccgatttg ctggttttga gcaggtcaag
    50521 gctggaatta tcaagtggcc aatgtctgtc ctacgcttga cttcggattc caaagaggat
    50581 ttgattaact tagctgataa gattttccag gaatggcgtc agtattcaga ttctagtgtg
    50641 cagattttag cagagacaga cgggacaccg catcacacca tcacaccaat agcgcgtaag
    50701 cgtgatggac agtttgagtt ggacttggtc ttgcgagaca atcagacttc agcagagcat
    50761 cctgatggca tctatcatcc ccacaaggat gtccaacata tcaagaagga aaatatcggc
    50821 ttgattgagg tcatgggctt ggcaatcttg ccaccacgtc tgaaagaaga agtggagcaa
    50881 gtcgcgagct atcttgtagg agaagctgtt acagttgccg attatcatca ggagtgggca
    50941 gaccaactca aatcccaaca tccagaccta acggataaag aaaaagccct tgcaatcgtc
    51001 aaggactctg tgggtgctat ctttgcgcgt gtacttgagg atgcaggagt ctacaagcag
    51061 acagaacaag ggcagacagc ctttatgcgc tttgtggaac atgtcggaat tttactagac
    51121 taggagcttt ctccttgcac agtcctataa aaagtagtat catagtgtcg tttgaaatat
    51181 caggaggaaa cgatgaaaga ctttcatttt gacgctatat ctgcctttga aaattacgaa
    51241 attgaaaaaa tgagagatgg tcacgttgtg gtgacgacca aagtagtgaa ctcgtcgctc
    51301 aactactatg gcaatgccca tggtggctat ctattcacgc tatgtgacca aatcagtggt
    51361 ttggtggtta tctcgctggg acttgatggg gtgacactcc aatcctctat caactacctt
    51421 aaggcaggaa aactcgacga tgtattgacc attaaaggag aatgtgtcca tcaaggccgt
    51481 acaacctgtg tgatggatgt ggatatcacc aatcaagagg gcagaaatgt ctgtaaagca
    51541 acctttacca tgtttgtcac aggccagcgg tcagaagaaa gacaggtaag gatatagata
    51601 aacaaaaaag aggcttacac ctctttttta gtttcagata aatcaatcaa tttctttaat
    51661 aaacttagca atttccttta caatctcagt aaccaaagca tttcccataa aaaacattct
    51721 cattttatca gatacctcta caatagaatc atcagataat ttctttttag ctgtccaatc
    51781 atctgggaaa tcctgaagtc gttcagcttc aatgggggta attaatctat atttattatt
    51841 tacaaataat aaatgtgtag aacgattaac cgttccttcg gatgtaagca ttgttcgtcc
    51901 aggaaggttt aaatcatcat aaggtgacat tcccccttct gaatagatgt attgatgtcc
    51961 gtcagaggat gttcgttcaa tttttttagg tcctctaaga tattgaaatt tttccaattt
    52021 tgactgatca gttaaaaaat atttttcagg tacttcagac tcatcttgaa gaatttctcc
    52081 tagagtgata ggattaccat tgtaattagg ttctgtatca atagaatagt actttccacg
    52141 cctcataatt cctgtattcc aaacagtacc agtaaaagta tctgaaactt caactatatc
    52201 atttggtaac tcataaaaca catgacgatt tttaactgct ataggtttaa taggaaattg
    52261 ttttgcaaat agaccttgat tgaaaatata gtcatcatac ctattatctt caaagatttc
    52321 ttcatttttt tcgtaaagat tgtcaatttt ttgggcaaag actgtatcat ttcgatatac
    52381 gaaaaagaat acacgacgtc ttcgttggct tcttccatac tcagcagcat taataactct
    52441 ccactcaaca gaatatccga gattattaaa agctgtgagc atgattgcaa aatcacgtcc
    52501 tctttgtttt gagggcgctt ttaaaagcct atctacattt tctagaatta agtatttggg
    52561 tttaatgatt tccgttgctc taatgatttc ccaaaataaa actccttttt ttccttcaat
    52621 acctttctca ttttttttac tacgagcaac agagtaatct tggcaaggaa aaccaccgac
    52681 aatcatatcg gcatccattt tggaaaattg ttcgtctgtt atatcagaga tactaatatt
    52741 gatgtttttg ctattgggga agtgataatc atagacctca aatgcgtctt gagatttacg
    52801 agatggttcc cattggtttg cccattttgt tttaaagagt tgcttatcgg cattttctaa
    52861 tcctatgcga aacccgccaa ctccagcaaa tagttcgaga actttcatct tttctccttc
    52921 atttttttac agtttaatcc attatatact attttcaatg attgatcaag tattaatgtt
    52981 tgctttagtt taatttgata taatataaaa gataggagaa gaaaatggat caaaacttat
    53041 ttaactataa cgatgaagat atcgatagtg ttattgaata ttctcataaa ctattaaata
    53101 gaaaattttc cgatgttatg gaggagtata atcgttcgct ttataaatca tatgacgatt
    53161 ataatgatag agtagtctct gaggtacaag ataaagcaat tagtatgaag tcaaaagggc
    53221 agtatggaaa ttatattgaa aaatatttct atggttatca gccaaatagt gactcggaag
    53281 ctgactttga aaaaataggt gtagaattaa aagttactcc ttttaagata aacaaaaatg
    53341 ggacacttag tgcaaaagaa cgacttgtat taacaatact aaactatatg gaggaaaatt
    53401 tagaggattt ttactccact catttatgga aaaaatgtgc aaagattttg ttattgtttt
    53461 acaatggctt aattcctaat caaacaatga aggactatgt cattgaaaaa atatttttat
    53521 atgaatggtt tgaggaagat atggcagtca tccttgaaga ctatcagaag attacagata
    53581 aaatcaaaaa tggaaaggca catgaattat cagaatcaga tggaaactat ttatcaactt
    53641 gtacaaaagg ggcaggtaaa ggaaaggatt taagacaaca accttttagt catgaattag
    53701 caaaacaaag agcttgggaa ttaaaatcaa gttatatgac ctatctgata aatcataaaa
    53761 tctttaatca atcagatcaa gaaagtgttc tggctaattt taggggtgag aaaaaatcat
    53821 ttactgaggt tattgcagag aagattcttt cctacaaagg tttttctgaa caagagttat
    53881 atgatagatt tgaagtgaat tccaaagcaa aaggtaagaa tagtactctg attagaaaaa
    53941 ttttaggctt aacaggggat ttagataaga caaaagaatt tcaaaaagca aacatgaatt
    54001 tgagagttat tcgagtagat aagaataatt tacctaagga agactctcca tttaaaactt
    54061 attgttttaa agaactagca gcaacagata gttgggaatc atcacatgtt tataatgaaa
    54121 tttataataa acgattcctt ttcgttattt ttaaggaaat tgaacctaag ctatttgtat
    54181 tagattctat caagttttgg ggatttcagg atagacaatt agaagaaatc caaagagtat
    54241 ggcaggaaac tagacaaatt atttctgacg gagttaaatt aactcaaaac ggtaataaag
    54301 tttcaactaa tttccctcaa agtaagataa acaaaattct atttacgaaa ctacatgcta
    54361 ccaatactta ttatgaaatt gacaaaggaa aatttgttgg gaaaggttca ttatctgata
    54421 cggatgaact tccagatgga cgtaggatta caaaacactc cttttggatg cctaagaaat
    54481 ttattaaaga aatattagat gggaattggg attgattgta tttataatca atttgtgata
    54541 aacaaaaaag aggctcgcac ctctttttct tatttctttt tatgatttaa tacggcattg
    54601 aggacaatag tgagtaggct ggctacgacg attccgtttg agaagaacat ttggaaggct
    54661 gtcggcatgc tgacaaagag attactgttg ttgagaccga cacctgcagc gattgaaaca
    54721 gctgcgataa ggaagttgtg ttcattgtta gcaaagtcaa ctcgggcgag gatttgcatc
    54781 ccttgaatag atacaaaacc aaacatcacc agcatggcac cgccgaggac ggagcttgga
    54841 atgatttggg caagggcacc aaacttagga agcagtccaa ggagaaccag gaaaccagct
    54901 gcgtagtaga ttggcaggcg ttttttgatg cctgacaatt taaccaaacc aacgttttgt
    54961 gaaaatccgg tgtaagggaa ggtgttaaag attcctccga gaagtacggc caaaccttct
    55021 gcgcggtaac cgttgcgaag gcgcgtgctg tcgattggat cttttgtgat atcagacaag
    55081 gctagataaa caccagttga ctcaaccata gacaccgttg cgatgataca catcatgaca
    55141 atagatgaga tttcaaaggt tggcatccca aagtagagtg gaattgggac atggacaagt
    55201 ggagctaccg caacaggaga gaagtccacc aagcccatag tagcagcaat ggcagttcca
    55261 acaaccagac caatcaaaat agagatagac ttgataaatc ctttggtaaa gatgttgatc
    55321 aagaggataa tcagaacagt aatagctgca agcaagagac tttgaccagt tggctctgga
    55381 acgttatttc ccatatttcc aatagcgaca gggatcaagg ttaaaccaat cgtggtaata
    55441 a
//
LOCUS       DAVHTH010000008        51060 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.008, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000008 DAVHTH010000000
VERSION     DAVHTH010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 51060)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51060)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51060
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.008"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            complement(29..112)
                     /locus_tag="VVR63_000476"
     CDS             complement(29..112)
                     /locus_tag="VVR63_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HEU6128528.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
     gene            complement(161..1579)
                     /locus_tag="VVR63_000477"
     CDS             complement(161..1579)
                     /locus_tag="VVR63_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HEU6128529.1"
                     /translation="MEGFLLNEQTWLQHLKEKRLAYGLSQNRLAVATGITRQYLSDIE
                     TGKVKPSEDLQQSLWEALERFNPDAPLEMLFDYVRIRFPTTDVQQVVENILQLKLSYF
                     LHEDYGFYSYSEHYALGDIFVLCSHELDKGVLVELKGRGCRQFESYLLAQQRSWYEFF
                     MDVLVAGGVMKRLDLAINDKTGILNIPVLTEKCQQEECISVFRSFKSYRSGELVRKEE
                     KECMGNTLYIGSLQSEVYFCIYEKDYEQYKKNDIPIEDAEVKNRFEIRLKNERAYYAV
                     RDLLVYDNPEHTAFKIINRYIRFVDKDDSKPRSDWKLNEEWAWFIGNNRERLKLTTKP
                     EPYSFQRTLNWLSHQVAPTLKVAIKLDEINQTQVVKDILDHAKLTDRHKQILKQQSVK
                     EQDVITTKKGYLSTIPVDRYPKKDIMGDKTVRVRADLHHIIKIETAKNGGNVKEVMEI
                     RLRSKLKSVLIVHYLKILYNRN"
     gene            complement(1602..1754)
                     /locus_tag="VVR63_000478"
     CDS             complement(1602..1754)
                     /locus_tag="VVR63_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000879507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEU6128530.1"
                     /translation="MLAGVAIATPALNPPYLTGGYKSTGNSQKNIRKSFGYKGFTKFQ
                     RMSNGL"
     gene            complement(1757..3142)
                     /locus_tag="VVR63_000479"
     CDS             complement(1757..3142)
                     /locus_tag="VVR63_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEU6128531.1"
                     /translation="MKQRGKRIRPSGKDLVFHFTIASLLPVFLLVVGLFHVKTIQQIN
                     WQDFNLSQADKIDIPYLIISFSVAILICLLVAFVFKRVRYDTVKQLYHRQKLAKMILE
                     NKWYESEQVKTEGFFKDSAGRTKEKITYFPKMYYRLKNGLIQIRVEITLGKYQDQLLH
                     LEKKLESGLYCELTDKELKDSYVEYTLLYDTIASRISIDEVEAKDGKLRLMKNVWWEY
                     DKLPHMLIAGGTGGGKTYFILTLIEALLHTDSKLYILDPKNADLADLGSVMANVYYRK
                     EDLLSCIETFYEEMMKRSEEMKQMKNYKTGKNYAYLGLPAHFLIFDEYVAFMEMLGTK
                     ENTAVMNKLKQIVMLGRQAGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSEMGYG
                     MMFGSDVQKDFFLKRIKGRGYVDVGTSVISEFYTPLVPKGYDFLEEIKKLSNSRQSTQ
                     ATCEAEVAGVD"
     gene            complement(3171..3557)
                     /locus_tag="VVR63_000480"
     CDS             complement(3171..3557)
                     /locus_tag="VVR63_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HEU6128532.1"
                     /translation="MMRLANGIVLDKDTTFGELKFSALRREVRIQNEDGSVSDEIKER
                     TYDLKSKGQGRMIQVSIPASVPLKEFDYNARVELINPIADTVATATYQGADVDWYIKA
                     DDIVLTKDSSSFKAQPQAKKEPTQDK"
     gene            complement(3573..3887)
                     /locus_tag="VVR63_000481"
     CDS             complement(3573..3887)
                     /locus_tag="VVR63_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HEU6128533.1"
                     /translation="MELKFVIPNMEKTFGNLEFAGEDKVVQRRINGRLTVLSRSYNLY
                     SDVQRADDIVVVLPAEAGEKHFGFEERVKLVNPRITAEGYKIGTRGFTNYLLHADDMI
                     KE"
     gene            4318..4908
                     /locus_tag="VVR63_000482"
     CDS             4318..4908
                     /locus_tag="VVR63_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HEU6128534.1"
                     /translation="MVDKREKLMNSFNQYGFLTFKQVIDENLHYKTLLKMVAEGKIDA
                     EEKGLYRLPDIYLDEWFVLQYRFPKGIFSLETALWLHGLSLTIPFNMTMSFPYGTNTK
                     NIKEADICPIILRSHYSEGIIEIERLPGQFIKVYEVERVLVECLRPVHQVDLQIIAPA
                     FKKYFQQNKIHLHKLFYYAQLFKVTDKLQSYTEVLS"
     gene            4908..5744
                     /locus_tag="VVR63_000483"
     CDS             4908..5744
                     /locus_tag="VVR63_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000492399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HEU6128535.1"
                     /translation="MFSNANSFKAKIKNISKDKGIPAQQVQQHYLIEQVLKLISTSSY
                     RDSFIVKGGYLIGQMIGLDKRTTMDLDVTLKGTEMSRENLIHIFEEILCSKTDGFSFS
                     VDKLEPIRQDDEYGGFSLKLNATFDTLKEVVFIDITTGDKITPREITYSMTSIFTNES
                     IKIWTYNLETVLAEKLETIISRGLASTRPRDRYDLFTLYKLRKEEINLEVLKNALENT
                     AEKRKSKDTIYNWEEQVRGIEISDYQKELWIRYQRQFKYAKDISFDNSVQVIREIMQQ
                     IF"
     gene            6027..6326
                     /locus_tag="VVR63_000484"
     CDS             6027..6326
                     /locus_tag="VVR63_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000869756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6128536.1"
                     /translation="MKVVNLYDLKQMGNKGGCTIQLIHHFPFGMGLGHLKKDYIEFKR
                     VGIVDGKAVEVTLREPYSRDLLQVVKSIKQRQKLIAYRYKEGKLLFVKEEASDVL"
     gene            6316..6804
                     /locus_tag="VVR63_000485"
     CDS             6316..6804
                     /locus_tag="VVR63_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6128537.1"
                     /translation="MSSEQQERMAVQYAERSLLFTVKSLLKILEWSRRQALAQDSAYK
                     IGVQKLEELLQSPYSIDTINLKKDFLDKPIDIEKFKAFLEKEEIPLAIAWQGDSLHFY
                     TKDRSILDNHLDQLLEKMVNDPEKLADFTMDKSLDDAIDEAKSQITFRQEGAVKQKEM
                     VR"
     gene            6804..8681
                     /locus_tag="VVR63_000486"
     CDS             6804..8681
                     /locus_tag="VVR63_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HEU6128538.1"
                     /translation="MYSGKKFLLFSLLGILLGYLFHRLTLLYDSYTGNSLDKWTHLLM
                     EGQDEVLQSPWNVSFTGKSSAFFLLGFVMMLLVYLYLETGKKQYREGIEYGSAHFGTL
                     KEKKLFYGKEFSHDTILAQDVRLTLLDKKPPQYDRNKNIAVIGGSGSGKTFRFVKPNL
                     IQMNSSNIVVDPKDHLAEKTGKLFLEHGYQVKVLDLVNMKNSDGFNPFRYIETENDLN
                     RMLTVYFNNTKGSGSRSDPFWDEASMTLVRALASYLVDFYNPPKTREQLIEESRLSQK
                     EHQNLLKRQKKEVEERKKRGRYPSFAEISKLIKHLSKGENQEKSVLEILFENYAKKYG
                     TENFTMRNWADFQNYKDKTLDSVIAVTTAKFALFNIQSVMDLTKRDTLDMKTWGKEKS
                     MVYLVIPDNDSTFRFLSALFFSTVFQTLTRQADIDFKGQLPLHVRVYLDEFANIGEIP
                     DFAEQTSTVRSRNMSLVPILQNIAQLQGLYKEKEAWKTILGNCDSLVYLGGNDEDTFK
                     FMSGLLGKQTIDVRNTSRSFGQTGSGSLSHQKIARDLMTPDEVGNMKRHECLVRIANM
                     PVFKSKKYNSTKHPNWKYLANQETDERWWDYQINPLNQSQENHLEGLRIRDLTFESSL
                     K"
     gene            8702..8944
                     /locus_tag="VVR63_000487"
     CDS             8702..8944
                     /locus_tag="VVR63_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6128539.1"
                     /translation="MITHFKGFVYGVDASAMFAQAMSLLQKGLIAVGAFLVVVGIVNL
                     ATNIKDGGPGVRNAILEIVGGVMVGAAGAFVTQISI"
     gene            8961..9815
                     /locus_tag="VVR63_000488"
     CDS             8961..9815
                     /locus_tag="VVR63_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TrbL"
                     /protein_id="HEU6128540.1"
                     /translation="MNLSLVSPFVYLASEKISAENLFEGFSVDLQSTVDLIKSLSSYN
                     PTVWTYMSSITKSVMQPLGVAILSVVLILEFSKMAKKIANSGGAMTFEALAPMLISYI
                     MVAVVITNTTVIVEAIIGIASHAIEQVASIVAHGGAKYDTISGLKGSGFIGRMIVGFF
                     ALLIWLVRIVSAAMVNLLVSIRFIQLYLMIPFAPLTIPTFLSDEWKSIGIGYLKNIMV
                     YAVQGVLIFLIVSLVPLFESAGKIAVSNGAGVLQSLAIMFGSLVQAILLIIALVGSQR
                     TARSILGM"
     gene            9869..10231
                     /locus_tag="VVR63_000489"
     CDS             9869..10231
                     /locus_tag="VVR63_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HEU6128541.1"
                     /translation="MNTRVFKDISKYQHRAWLGFTTRQIIFVLPAFIVTIIVLGLNLF
                     FWQFGDWFVYGFVFAFTIPLMLFGVYKPNDLYFEHYLKYRLHFELTVPLRTITGKKGH
                     EHEKKIKYIKETKSFNDL"
     gene            10179..12536
                     /locus_tag="VVR63_000490"
     CDS             10179..12536
                     /locus_tag="VVR63_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEU6128542.1"
                     /translation="MKRKSNTLKKQKASMTYKKEEVKGKKEEVLPSTANTISYQALYQ
                     NGLMQVKEDYFSQSYLLGDVNYQTVGLEDKGAIIEKYSDLINSLDDQTNFQLTIFNKR
                     LNLEKFRQSVLYEEKEDGYDTYRKELNRMMNQNLDSGENNFSAVKLISFGRKDSNPKQ
                     AYRSLSQIGEYFKSGFSEIDARFESLAGEERVNLLADMLRGEHHLPFSYCDLTRSGQT
                     TRHFIAPNLLDFKNKNYLQINDRLLQIVYVRDYGMELGDQFIRDLMQGDLELIVSLHA
                     QSSTKADAMKKLRTKKTLMESQKIGEQQKLARTGIYLEKVGHVLESNIDEAEELLKTM
                     TETGDKLFQTVFLIGVFGQDEEELKQALDTIQQVAGSNDLMIDKLPYMQEAAFNCLLP
                     FGCDFLEGVSRSLLTSNIAVNSPWTSVDLQDRSGKYYGINQISSNIITIDRSLLNTPS
                     GLILGTSGAGKGMATKHEIITTKIKESGENTEIIIVDPEAEYSVIGRAFGGEMIDIAP
                     DSQTYLNVLDLSEENMDEDPVKVKSEFLLSFIGKLLDRKMDGREKSIIDRVTRLTYQS
                     FKEPSLEEWVFVLSQQPEEEAQNLALDMELYVEGSLDIFSHKTNIQTGSNFLIYNVKK
                     LGDELKQIALMVVFDQIWNRVVRNQKLGKKTWIYFDEMQLLLLDKYASDFFFKLWSRV
                     RKYGASPTGITQNVETLLLDPNGRRIIANSEFMILLKQAKNDREELVQLLGLSKELEK
                     YLVNPEKGAGLIKAGSVVVPFKNKIPKGTQLFDIMSTDPDKMASN"
     gene            12548..15361
                     /locus_tag="VVR63_000491"
     CDS             12548..15361
                     /locus_tag="VVR63_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEU6128543.1"
                     /translation="MKDKREIIRARKAFRRSLKDEKKFLKKGKKEVKKQKKDSAVLDE
                     KAWKKEIKKKLEEMREASKARVKQANEDYNHILQNSPPSLLNRKELRDRRLPHARKRL
                     KIAKKQYREAKVEAKEERKESRKERKTNQKFLYGQESKAKSNFFFQGKSLEELKVKKE
                     VKTAKENLKSTKQAYKSKKVSRKAKTFLYVLGREGGELASENEDLDGYRTLQETIRKG
                     KRYSRLSYNLGKASVKTGQATCRFTKKRLTNTKERYHHFKDGKGWKLAKDKPSSFKNR
                     FRKLKKQGLTSVRNIYQKLKAAFSFFTFAAGNPVTWIVGGIVFLLLLIMSFFLGFSSA
                     SLIQQDEFELTKAYTHLTWEDAEHTRTNDKGITYYTKVDDVMGYMNFKFHDYELHKPV
                     HLFSSETYKDYLSTLWHDLNDGEDLKSMQDLYETPKYKLSKDDQEEMKELKEEGIYAS
                     MQELDNPFEGKSNEDSLTMTYRYGYYDLDGKPTLQEYILLEAKAHQTIVAPMDGVVSL
                     DGDNVILTNGKGENESRLTLYSIHNGRAIEGTRVLTGDIIGETPDDTGLKVSYQKYKN
                     KKEKLVYVNPQFYFPKVIQLQTTILPAIGQFGGDEFERAKHIYEFLKSQGASPQAIAA
                     ILGNWSVESSINPKRAEGDYLSPPVGATDSSWDNETWLAIGGPAIYSGAYPNILHRGL
                     GLGQWTDTADGSTRHTALLNYAHSKNKKWYDLDLQLDFMLHGDSPYYQSWLKDFFGNT
                     GSAANLAQLFLTYWEGNSGDKLLERQTRATEWYYQIEKGFSQTNGGQAKSDPQSLEGV
                     RGDLYDHSVPGGGDGMAYAYGQCTWGVAARMNQLGLKLKGRNGEKISIINTMGNGQDW
                     VATASSLGGETGSTPKAGAIVSFVGGTHGTPAIYGHVAFVEKVYDDGSFLVSETNYGG
                     NPNYTFRKISQADSAISFAYTTK"
     gene            complement(15392..15580)
                     /locus_tag="VVR63_000492"
     CDS             complement(15392..15580)
                     /locus_tag="VVR63_000492"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6128544.1"
                     /translation="MVYRVCKPPSQSVYSGVCHRLALTSKIAIGFRSGVRHRLALMSK
                     ITIRLTMSRLLIYTIYST"
     gene            15599..16165
                     /locus_tag="VVR63_000493"
     CDS             15599..16165
                     /locus_tag="VVR63_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6128545.1"
                     /translation="MANSRDYRNPNYTEKIKLQRFFTQLQIAASFFKEHFVGKIMYYE
                     TEIESVELHFSPTNFMHLCGVDYRKGAGSFFDDCLNRHVIIDELKIKKDGTTMQKLQV
                     LGSIEELLGKHVHLTGSGRYLYLEFDYALRTRKQILALTLKETSRKIVPQSLLDLKRK
                     TVFPKGQKVISIYSKHLQTSELFYYLKD"
     gene            16317..16727
                     /locus_tag="VVR63_000494"
     CDS             16317..16727
                     /locus_tag="VVR63_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell envelope biogenesis protein OmpA"
                     /protein_id="HEU6128546.1"
                     /translation="MEGIYQRDSDQDGLTDAQELALGTNPLSADSDGDGRSDLVEVEE
                     GTNPLEKDLQDIDQTSITEPSSVFMEMKQKISDMMESHYKEFIQALISIETGIENEQD
                     LEDLYTYYMRTDSISLLSSDLETSPQKVEMEIEL"
     gene            16775..22072
                     /locus_tag="VVR63_000495"
     CDS             16775..22072
                     /locus_tag="VVR63_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEU6128547.1"
                     /translation="MEVMKLLAMFRGTIPKDREKMDLFLRYQAQHFDEKWQDLVESFL
                     AEEGKIEEIPHVYSFHQDIISFLEASSENNDQDLESYTRNFGQAGLSKLSQLSNFEKN
                     LVLEVATYNLSTRFYIQSEKEKLEPLSELVCLQNQDVNLVNVYRVANNLSDRISRDIE
                     EFLLMVDSKELTKEVLEIHFEEKEGDVLAYLGSELMATLDTVTDLVHHEENYTQLPLT
                     QKLKIITHFDDVKARSEKSNQVEEVLSPSSDIEQETEETNSFSNVDKIVEEALREYPI
                     GSQVSYKGQVFQLVSIENAQLNDLIRLELFNDSNQLFEENPILYLNSLEEIEQVLSLV
                     ELEKEDSEIEIDSSSESQEIDLFSYLEEEKENEKDKETETLIVGIEETDVPVQDFVFP
                     DDLEDFYPKTNREKIETNIAAIELVKRLEKEGRQANPEEQELLAKYVGWGGLANEFFD
                     ELNPKYETERLTLKSLVSKSEYSTMKQSSLTAYYTDPMIIRQIWQKLLDDGFEGGRIL
                     DPSMGTGNFFAAMPRSIRDKSELYGVELDSVTGAIAKKLHPNTHIEVRGFEEVPYQNN
                     SFDLVLTNVPFGNFRIADKNYDKPYMIHDYFVKHSLDLVRDGGQVSIISSIGTMDKRT
                     DNVLQEIKTNTHFLGGVRLPDTAFKSIAGTRVTTDILFFQKDQAKNLNEEELVFSGSI
                     PFEEDKRVWINPYFDGKYNTQVLGEYEVRNFNGGTLNVKGVSETLSTDIMKALENVEA
                     PKQIDNFLKAPVFIQEEVDNSLPSRIREDLALYSFGYERNQIYYRDTHGIRKSSKVDE
                     ISYYVDEKGDFKAWDSSLSEHKIDRFVQLHLTDEEALDVYKSEEASKRGKYKGLFKKT
                     VFYESPLSDKDISRIKGMVDLRETYQSLIEIQRHQDYSRTDFQVLLSKLNHNYDRFVS
                     QFGYLNASVNRNLFDSDDKYSLLASLEDEYIDSKDQKVKYKKSLAFEKALVRPERVIA
                     RVSTALDALNSSLSDGRGVDLDYMVSIYPEHSQAAILDELGDQILIDPESYLRGERKY
                     LSKNQFLSGDILNKIEVVQLLVEENNQEYDWNHALDLLESVRPPRIHLADIEFKIGSR
                     WIPQSVYGKFAFECFTNREFELSSPDVEQVIEANPVDGQVHLRTSFAYRYPSAKDSSL
                     GVSGSRYDTGRKIFENLLNSNQPTITMTVTEGEKKKTITDLEKTSVLRAKEQHLQELF
                     QDFVSRYPEVQQVIEESYNRLYNRTVSREYDGSHLVIDGLAQNISLRPHQENAIQRIV
                     EEKRALLAHEVGSGKTLTMLGAGFKLKELGMVHKPLYVVPSSLSAQFGQEIMKFFPTK
                     KVFVTTKKDFVKARRKQFVSRIITGDYDAIVIGDSQFEKIPVSKERQMNYIEDKLNEL
                     REIKTHSENKYTVKEAEQSISGLEKQLEELQRFNRDSFIDFENLGIDFLFVDEAHHFK
                     NIRPITGLGNVAGITNTTSKKNVDMEMKVRQIQEEHDFKNIVFATGTPVSNSISELYT
                     MMNYIQPDILKRYQVDYFDSWVGAFGEIQNSMELAPTGDKYQPKKRFKKFVNLPELMK
                     IYKETADIQTQDMLDLPVPEAHIIPIESELTENQKLYLEELVMRSDMVKCGTVDPSQD
                     NMLKITGEARKLAIDMRLLDSSYSLADNHKLLQVVDNVERIYREGMENKATQMIFSDI
                     GTPKKKDNGFDVYSEIKALLVDRGIPSKEIAFVHDANSDEKKNSLSRKVNAGEVRILL
                     ASTEKGGTGLNVQSKMKAVHHLDVPWRPSDIQRASVKAV"
     gene            22636..24447
                     /gene="ltrA"
                     /locus_tag="VVR63_000496"
     CDS             22636..24447
                     /gene="ltrA"
                     /locus_tag="VVR63_000496"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006740542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HEU6128548.1"
                     /translation="MRNPQNVLNNLTKHSKDKNYQFERLYRLLYNKEMYLVAYQTIYA
                     NPGHLTPGVDELTIDGMSIARIDQLIDSLKDESYQPHPSRRTYIPKKNGKLRPLGIPS
                     FDDKLLQQVIKMILEAIYEGQFEPSSHGFRPNKSCHTALTQIQKTYTGTKWFIEGDIK
                     SFFDNINHDVMIHILRERITDERFLRLIRKFLNAGYVEDWKFYKTYSGTPQGGIISPI
                     LANIYLDKFDKYMTDYVKNFCQGKYRKRTPEYRQNEIALGKARRALECVSTENQRQEV
                     IQRIRQLEKERVLIPHSDPMDSSFKRLTYTRYADDFICGVIGSKEDAHRIKADIKDYL
                     EAVLKLELSVEKTLITNARDKAKFLGYHLYIRQSNLAKRDSAGRLVRNYTGRLVLEVS
                     IETIRDRLLSYGAMKMTYHRGYEVWKPTARYFMKDCDDLEILERYNAEIRGFYNYYCI
                     ANNSSILHRFKYIMEYSMYKTYATKYRTTKSHIIRKYKKDGQFSVQYIGRKGDTMTRY
                     LYNGGFKRQKKSFLENDNLPNTAKYFSRTNLIDRLKASRCEYCQATDSSLEIHHVRKL
                     KDLKGKTFWERLMISRQRKTIALCKDCHKKLHHGKLD"
     gene            24528..25499
                     /locus_tag="VVR63_000497"
     CDS             24528..25499
                     /locus_tag="VVR63_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase SNF2"
                     /protein_id="HEU6128549.1"
                     /translation="MVRRWVLSLQRNGRIIRQGNENKEVDIYHYITKGSFDNYLWATQ
                     ENKLRYIKQIMTSKEPIRAAEDIDEQTMTASDFKALATGNPYLKYKMELENDLTLLEN
                     QRRAFQRSKDHYRHTISYCEENMPILEKRLSKYEGDIQQSEISKDQAFSMRVGKQSFD
                     QRAEAGESLHRLIRHNQADSKEFRTLASYRGFDIKMLSLPTNQPLPETFSVKIVGENQ
                     YSVSLDLYSPLGTIQRLQHTIDHIKEDQVKTQNLLDELKDKWNTAKVEIEKNFPKEED
                     YQTKKAEYDVLAPLIETETDLDTIDQALRQFHEKGKEKQEQLSFELD"
     gene            25574..25858
                     /locus_tag="VVR63_000498"
     CDS             25574..25858
                     /locus_tag="VVR63_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6128550.1"
                     /translation="MMEDTYYQLEEALVQGFQTPEEYQAYKELKEHYEEVTGDYSFSK
                     RELTSQLEIALQNHRGVDFEEYEKKDYLELVQKLEEFDSSLATHYRQLID"
     gene            25872..26162
                     /locus_tag="VVR63_000499"
     CDS             25872..26162
                     /locus_tag="VVR63_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000998897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6128551.1"
                     /translation="MNDLLLIPVIFLAVGGILILLWRLFLIASGLFLIGFVSFLIFVE
                     VYGIYLLFTETELYTADLAQNGLFGFTTFFIIFNLVLLALACWAGYKWKRGY"
     gene            complement(26245..27105)
                     /locus_tag="VVR63_000500"
     CDS             complement(26245..27105)
                     /locus_tag="VVR63_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000025784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU6128552.1"
                     /translation="MTILSDKLKAKRKEKGFSQKTLSEGICEQSQISKIERGNYMPAA
                     DLLYKLANRLQVPLDYFFDEQIEMTSNITPFKKLAEKLLEDRNYEDLEYLLNLEKEKS
                     QYLSTEDEFYLLWIQSIILFYLHSSKDEAIASLENALPKLSVSSSVYLKLLNTLSNFY
                     FSVGRDAEYEENNSLLISLYQEKDLNHQEYLFGYIRVKHNFAYYLHSKGKELEAVQEA
                     LETIDFCKQKETSYQLAPLLTIVANAGKDFLKHDEILDYYLQARDICKIYEHKLMMAK
                     IDHFLKDKDR"
     gene            27296..27469
                     /locus_tag="VVR63_000501"
     CDS             27296..27469
                     /locus_tag="VVR63_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000025229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6128553.1"
                     /translation="MSILAKFRKIIFMLSFLGLFGSGFFFKEPVNQSQYTWESRIIQQ
                     AVTTNEVDLGLAD"
     gene            27647..28582
                     /locus_tag="VVR63_000502"
     CDS             27647..28582
                     /locus_tag="VVR63_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6128554.1"
                     /translation="MRNPVIQTFNLSKSYDGKIVLDRIDFTLRQGEIYGLLGRNGTGK
                     TTFIKAILGLTAMDSGEVNILSEKLLGEFSKDLLSQIGVVLDSASFYPNLTGPENLSI
                     FARLRGISLKQVEQALQVVGLDGENKKLFKQYSLGMKQRLAIANAIMHQPKILILDEP
                     TNGLDPIGILEMRRYLKELSTNHGISILISSHIISELEKLVDRVGILHDAHLMAEKTM
                     KELIDGADKRKIHLIVSDAPQAKEVLCRINLQEQISILSDIELELQGESPTFDIAVVS
                     NSLKDNGIVLKEYSYKNNESLEDYFKRITGGEGIA"
     gene            28575..29315
                     /locus_tag="VVR63_000503"
     CDS             28575..29315
                     /locus_tag="VVR63_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6128555.1"
                     /translation="MLDLVKIEFLKQRHQKLNFVVYGVVSLYLALICYYVNDARGLFD
                     SFPFVYKFSLSYLNFLILPLYCVSYTIQAFGLEYRYRIMNNLKLASANLMKTFWAKIL
                     YIEINALCIMLFTYISVSLFALLSRFSSTVSLSLLLRFFYLCMSSGILIPMGVFPLVA
                     LVMIKVRGKEIVGNLVGVMYVLVSFFLARTSPNISPVTSANSLIWEGNREGVVLQQPA
                     ILSIVVLGLSLLVLSFLSIKSWLRKVDE"
     gene            29316..30044
                     /locus_tag="VVR63_000504"
     CDS             29316..30044
                     /locus_tag="VVR63_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000928810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6128556.1"
                     /translation="MLMLEFTKLRRRKILYMIPFVAILLFLLEFMIGHQIYQGHSYGS
                     VNGWYVENGFFFLNYYFLLPFASMILVDLIRIEQVSKTISNLRLIPVDLKQLLQAKFM
                     LALLINLLVSEFTFLAMLVLELMDGDFAFSSLAMLSWGVVYGAIAFAYTLSAGIIVLF
                     LGKYRKELILALPLAFLLSFAGLFALTTVVGRYYLANLLLIIMEQFTALTVSVYAIWL
                     VTLVACLLYLLADKRMMNIIFAYK"
     gene            30189..30404
                     /locus_tag="VVR63_000505"
     CDS             30189..30404
                     /locus_tag="VVR63_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001286517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plantaricin C family lantibiotic"
                     /protein_id="HEU6128557.1"
                     /translation="MSDWKKPIYESLSTEGNPAGDILRELSDSEMDQAMAGGTARSYC
                     ACYSGEHSCGRGCTITTECPFLTFICC"
     gene            30487..33738
                     /locus_tag="VVR63_000506"
     CDS             30487..33738
                     /locus_tag="VVR63_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001080431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 lantipeptide synthetase LanM family
                     protein"
                     /protein_id="HEU6128558.1"
                     /translation="MNRKLNITDFKDASYFSERKISSHDLGDGLKSRKRKEYWDNFIG
                     EGSNEFWKYLQEKNDFSKHDLDIFLEEHTYDVKDIDSFSHMDEFIEFFFKRNDYTLPE
                     FYIVDSEGKRKPIFSNFVIPFLKFAAYKLEDNLSSQNLKVTRDVLNSLLIALFQQILN
                     ISYRTLILELQVLKEQNMLKGETGEKRFKYFSEIYLSDHFWDILKEYPVMFRLIIENI
                     QNWVTNNVEFLTNLKEDKALLQEHFSINGELTKIESGVSDFHNHGKSVYLLWFGTNKL
                     VYKPRDLILDVKFQNLLSWYNLKFNKNLYVTNILNRGNYGWVEYIEHLPCTYESDFIQ
                     FYTHLGYLLFLLFAMRGNDIHFENIIAKGNRPVLVDIETLFHNTTEYRKEYETADKLI
                     FSLLEKSVKRVGILPNIVWGKDGNSGVDISGLSSSAGEMIPIERASIMHSMTDEMKIG
                     YEQSALQSKDNQPFIQSGKDVDLNSYKNYVSAGFKEAYEIISKDPSSIEEFLVEIEKF
                     NNAYSRQIMRPTQFYSNLIQTSYHPSFLRSGLDREMLFSKVWKIVFEDKKVQRIASSE
                     FESLLLGDIPLFQTKISDRFLCSELTKYQNFFNISGMELAIQQIKDFCQKDMEFQLNL
                     IETTLNYDPSYNLVQDSFVPLKPSVKVIRNLNQKEIQETKSRIVPLTEKIADYLSKIS
                     YSGTSGDICWVDMNILGEKTNDWNMVPIGCDLYNGISGIMLFYLFLYLETKKKDYLIY
                     LKKCYRSLKYYLDSRKQFATHSQVLFGGFSGETPIIYVLLLLKTRMPEHFNSDELDVY
                     IYDIIDDLKKGYRYDENFDVLVGSAGAIIHLLNVFEVTRDEELLILAHDLFSHLEKNS
                     TKITVEGQDGRAWKGTMASNPLAGFAHGVSGIVWALSKLSRYFPEDKKLKTIIKQGII
                     FENSMFDTEKSNWSDYRETESGIKYKDIVENIPVSWCHGAPGILISRLELYKNNTLNV
                     EFRRTMKSDMDVAIDTTIKYGFGKSHCLCHGDLGNLNILFYVAKKMSSEHLYNVVYSY
                     LNTILDDLESENWKCGLPYKNSPSLMSGIAGIGLGLLTLNNLSIPSVINLEIW"
     gene            33745..35868
                     /locus_tag="VVR63_000507"
     CDS             33745..35868
                     /locus_tag="VVR63_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="HEU6128559.1"
                     /translation="MKKVKFIQQLSETSCGLACMAMILDYYGHEANLYELCCDFENSR
                     DGLSIREIKDIASYFGLDSKATEILNIKKFLGNKFVEPYIALTQNAHYIVVEKHNEHS
                     VVFIDPERGRITEDISNFANNISGIVIFFSPNRKFTKKKKHSNFFKILKIGKIDIKRL
                     CYISLISILVQSLTLLLPLLTRFIIDNVISKGEMYRLGMLFSIFSLITFYALFSFIRT
                     KLIITVEKRYIFTLKDKIVGKIFTLPMKFFDSRSSGEIVTRINNLDSLEKIISSGISS
                     LLIDLSTIIIAFIAMAMISLYFTLIITCFAIFLFIVLYFLLKKLEEKNSNFISSKELT
                     QGYLMEIFSNLLFLKVSAKGDVSYTKWKEMFSNELKFDVERENYLNIFQTFISIYRLV
                     PNLLILILGGLEVQQHMMSLGSLMSFLSLVSLLLSPITLIVQNCFQFQFCFTILDRVF
                     DIIYTPEEKNQFSISKLPPFEMMTFRNLSFAYSSACKVIYDISLTIKKGERIAIVGRT
                     GCGKTTLIKLLLRLYDVEKNTILYNGNDINLFDLNSYRKSFGVVLQNDVMFNDTVISN
                     IDLTHSHSMEDVISAASLAELDIEINNMPMGYYTSIGDNGNNLSGGQRQRLAIARAIL
                     QNPEIIIFDEGTGQLDTITEKKIMDNLKHKGITQIFITHRLSNAQEYDNIIVMDNGKI
                     IDSGKHDELCGKEGMYKRLFETSYN"
     gene            36089..36730
                     /locus_tag="VVR63_000508"
     CDS             36089..36730
                     /locus_tag="VVR63_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEU6128560.1"
                     /translation="MLNKVKTKALISVGAVAATSFILMVGYTIGQHSTAKQSRKEIEL
                     AATKLVEDKQAEDKASILSSDTVKEFLTQYYTKEKLGENNTRIQPYMTESAYSQELSS
                     QNDAMNQVYKDYILDYHFEKADIFVNQTTNQAIAMVSYNVTYVSDLKNANQSKTNQTE
                     TRTVKLSYSKLPGKLLVNQVQVWKSGLDDLDKVTPKTLEESSSIPSLPNTTTK"
     gene            36740..37825
                     /locus_tag="VVR63_000509"
     CDS             36740..37825
                     /locus_tag="VVR63_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HEU6128561.1"
                     /translation="MEIEECKKISILDVANRLGISFKQVSSSVYEHPEHDSFRIFSTT
                     NTFKWFSRDIQGDVIDFVRLVKGISFKEALAFLSEEPFQKEAVQEKRERPFYYPLKRI
                     EDSNCSLARYYLTECRGISEEIIQKMIQQGLMSQASWKTNETVEPVIVFKSFDHRHKL
                     QAASLQGIYKNHSLPRERLKTILKGSHGHVGISFDIGKPNRLVFCESFIDLMSYYELH
                     QQNLFDVRLVSMEGLKRSVVAYQTLRLIAEENQKLEFLDTVIPSKLLPLINTIRDTTS
                     YFDNHPDLLTLAVDCDDAGKDFSDKLSRSGFPVFLDLPDNESGKEKRDWNDILREKKS
                     DLQLMIENAKETLRNQPVRQTSQCLEL"
     gene            37876..38109
                     /locus_tag="VVR63_000510"
     CDS             37876..38109
                     /locus_tag="VVR63_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6128562.1"
                     /translation="MTIIERLEEKVTRQESKVARETEKLAAYKEQLETAMFATFKRRQ
                     SISHMSFEEALDHAFGKERQFDDSEFRKDEMSE"
     gene            38106..38489
                     /locus_tag="VVR63_000511"
     CDS             38106..38489
                     /locus_tag="VVR63_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000159213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein"
                     /protein_id="HEU6128563.1"
                     /translation="MTKDWNFNQPLESKSENQEDPDKIAALFGNHQGGNEVNYEAAFQ
                     KRKQAPVTESNSSSKPKVTEVRTGKETDITTSYQQHLKRLIADNNSDIQSSQKKIEEL
                     HTLIDTKNKDNKKLQSIYDAISELH"
     gene            38527..38799
                     /locus_tag="VVR63_000512"
     CDS             38527..38799
                     /locus_tag="VVR63_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6128564.1"
                     /translation="MFTKLFKKNQDNSDVFKKLIHRLSDMSIQDLKKIDRLLDIIFTP
                     DQGSEQLKTEATYREETLDDTLKEAKNQLHMEQLEKNLERFRKNSQ"
     gene            38869..39345
                     /locus_tag="VVR63_000513"
     CDS             38869..39345
                     /locus_tag="VVR63_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003042293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU6128565.1"
                     /translation="MIGKNIKSLRKTHDLTQLEFARIVGISRNSLSRYENGTSSVSTE
                     LIDIICQKFNVSYVDIVGEDKMLNPVEDYELTLKIEIVKERGANLLSRLYRYQDSQGI
                     SIDDESNPWILMSDDLSDLIHTNIYLVETFDEIERYSGYLDGIERMLEIFEKRMAA"
     gene            39345..40103
                     /locus_tag="VVR63_000514"
     CDS             39345..40103
                     /locus_tag="VVR63_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003042596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HEU6128566.1"
                     /translation="MGIQDYTDSQFKQALARNIRSLTRGKKSSKQPIAILLGGQSGAG
                     KTTIHRIKQKEFQGNIVIIDGDSFRSQHPHYLELQQEYGKDSVEYTKYFAGKMVESLV
                     RELSHLGYNLLIEGTLRTIDVPKKTAQLLKSRGYEIQLALIATKPKLSYLSTLIRYEE
                     LYAINPNQARATPKEHHDFIVNHLVDNTRQLEELAIFERIQIYQRDRGCVYDAKENTT
                     SAADVLQELLFGEWSQVEKDMLKSGEERLKDLTN"
     gene            40579..41367
                     /locus_tag="VVR63_000515"
     CDS             40579..41367
                     /locus_tag="VVR63_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000214003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6128567.1"
                     /translation="MTTTKNPWNQLSNVDINGEQAILATEDVELIKKYTSTKHYKNLK
                     DDIYRLQLGFCPQQFVGDIQNADIIVLSKNPGYTPEFKTLYDHDKNYQKTLLNNLQLK
                     GNLYFHAFDLDTNEFGYWAKKFKVWFDDVDNLQDLKEKLPWFSKHVALAEYFPYYSTK
                     YDDKLNDFISKEGYFPTQKFLFNLIRERVLDDNDPVIIIITRSYNKWYDAIPQLKEYK
                     NCYETSNPSNPSLKPENLLKVKRYSAKKEVEKVLEDSLKKLEHK"
     gene            41606..41854
                     /locus_tag="VVR63_000516"
     CDS             41606..41854
                     /locus_tag="VVR63_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6128568.1"
                     /translation="MNYQKLNDITGATKNEKDKYYVYGLYEEGKQLPFYIGKGEGTRL
                     ISHIDEALTEINQEENIQISKKIQIIRKHKGKIIPVII"
     gene            42025..42744
                     /gene="catA"
                     /locus_tag="VVR63_000517"
                     /pseudo
     CDS             42025..42744
                     /gene="catA"
                     /locus_tag="VVR63_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032488880.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type A chloramphenicol O-acetyltransferase"
     gene            complement(43540..44463)
                     /locus_tag="VVR63_000518"
     CDS             complement(43540..44463)
                     /locus_tag="VVR63_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002499696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /protein_id="HEU6128569.1"
                     /translation="MEKYTEKKQRNQVFQKFIKRHIGENQMDLVEDCNTFLSFVADKT
                     LEKQKLYKANSCKNRFCPVCAWRKARKDALGLSLMMQYIKQQEKKEFIFLTLTTPNVM
                     SDELENEIKRYNNSFRKLIKRKKVGSVIKGYVRKLEITYNKKRDDYNPHFHVLIAVNK
                     SYFTDKRYYISQQEWLDLWRDVTGISEITQVQVQKIRQNNNKELYEMAKYSGKDSDYL
                     INQKVFDAFYKSLKGKQVLVYSGLFKEAKKKLKNGDLDYLKEIDPTEYIYQIFYIWKQ
                     KEYLASELYDLTEQEKREINHKMIDEIEEEQ"
     gene            44792..45514
                     /locus_tag="VVR63_000519"
     CDS             44792..45514
                     /locus_tag="VVR63_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6128570.1"
                     /translation="MAESALINLINFSKENEELTNLVSGHASKREKATISKDGLIQAR
                     SIENFIDNYALSDFDFSTIKEKCVFIKINNSFQADDTTEDIYHNVRGVWNISESRKKD
                     LEYALALYRGVCVGVYKIQGWKKAYEHSSEYPFPTRKEGGKIETSEETIVKYSNIEDL
                     KKDYPELYKRSFSNSEFPQKSLDKWRNRSFFYGNWDGSDVPQHLAQCLNKRIINIPKF
                     TKSVKEFKSIDNQASVIYNDLK"
     gene            45836..46453
                     /locus_tag="VVR63_000520"
     CDS             45836..46453
                     /locus_tag="VVR63_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6128571.1"
                     /translation="MANSSEAHGRVYIKASNLKTIEDFLLIQEERNKYVYYPTDIIDS
                     QSNISDIVSSRTTQENGYYICNMWFTAEGRWCFENNIDDFFDCTLFQDTDDVLIRQMK
                     EYVCSQDIQIKFEYVDAEASQNFVKEQEATITYNSKTKDISIDVKTIKDLPYTAENLI
                     VYGYYECDEIVSVQFLLDYYDDYLRGNEFYLKHKDGIVPILERQQ"
     gene            46542..46766
                     /locus_tag="VVR63_000521"
     CDS             46542..46766
                     /locus_tag="VVR63_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000644601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6128572.1"
                     /translation="MKAIVKNPKRLFELLRLYFVPVKGRKVVHVPAYAYKEDENEKIY
                     LHNNELHLSKKMFEFLVNQGLDLVECLPEE"
     gene            46859..47425
                     /locus_tag="VVR63_000522"
     CDS             46859..47425
                     /locus_tag="VVR63_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000180154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HEU6128573.1"
                     /translation="MTNAKEFALTAHKNQTRKGKITPYSFHLFLVNNILETLTEDPHI
                     IATGWLHDTVEDTDVSLEDIKQEFNDEIYSYMSLESEDKSIKDWQTRKELQLAKFREA
                     AEDESLRKVLLVTFSDKLANLMELYQDYLIIGGLLWDRFNSKDPKKQRWYFNEFYKIF
                     KDNQDLFSKNKDILNNYKEILKLLFYNN"
     gene            47478..48182
                     /locus_tag="VVR63_000523"
     CDS             47478..48182
                     /locus_tag="VVR63_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001039670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family hydrolase"
                     /protein_id="HEU6128574.1"
                     /translation="MNKPIAAIFDIDGTIFRDSLLLKHMEKCVSYDVFPNSVNSEIKF
                     HKNAWENRELDYDDYLYIAATLYTKYIADKDILDIDFVAKKVIEKESKKLYRYTRDRI
                     KWHKEQGHQIIFISGSPDFLVSKMAEKLGADIWYASNYLQLDSKYTGEVIPMWDSTSK
                     LQVLKKLFIDFEKSYAYGDTTGDFTMLQSVGFPTAINPNKKLLDKITMEKLDCKIIIE
                     RKDVIYKLDEVTHGIY"
     gene            48169..48435
                     /locus_tag="VVR63_000524"
     CDS             48169..48435
                     /locus_tag="VVR63_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6128575.1"
                     /translation="MEFIRAANQFIENYYPREDLDRIESIEIGIRDSENYSRYFLEIQ
                     KQSEEFECDFFNFDNIDYYVVDDSVHFKQIINLENSSYVFWKDY"
     gene            48852..50648
                     /locus_tag="VVR63_000525"
     CDS             48852..50648
                     /locus_tag="VVR63_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NTPase"
                     /protein_id="HEU6128576.1"
                     /translation="MSGSFSDSPTHDDKFSIENYINGLSNFIIECETPLTVAIQGDWG
                     TGKTSIMYQVEKRLNPEKQDKKIQTIFFNTWQYSQFDMGNNLAVALITDLISELNVED
                     SKKKQFFKKAKGALSKGLEYVNLDFGILNGEKLTEKFQDLIIGFGERTDDIKHLKENL
                     QDIINDAIKENKSDRIVIFIDDLDRLVPEKAIELLEVLKLFLDCEHCVFVLAIDYNVV
                     VRGAKSKYGKDLDDEKGKAFFEKIIQVPFTVPVANYDLQNFIESSLKKLDFCFDKNNK
                     ERNQLETITQLIRYSIGNNPRSINRLFNSVSLLMYINNGDKVDHDEKLMILAMVCFQL
                     RFEEAYNYLLTAYNNSPEDSDDIESYLIDLLENSFELLDDEVYYNSLVSLLGKFTFKD
                     KKDRDDFTNFYRTLKELLGYNEQGLTMEQFNKLIEKMTFSNAVSIGNTDTITADKKKQ
                     NHAPNEDVQFVIRKLFNTLVGDENYFDLKKPELFGKETREKREAPLSEEFISIPNEFD
                     RIRLTRGKGQGLNIYSSHNKSNFIYISGDTHGRMLNDGMAIVVNNNLVEKIKDNILAS
                     DLRSEELYHEFEMNFRDNLNKLLSKASKILNN"
BASE COUNT        17603 a         7787 c         9484 g        16186 t
ORIGIN      
        1 gtcactggta ggaattaatc taacgtattt atttatctgc gtaatcactg tttttagtct
       61 gtttcaaaac agtagatgtt ttatctacat tacgcatttg gaataccaac atgacgaatc
      121 cctccttctt aattacaaat ttttagcatc taatttaact tcaattccta ttatacaaaa
      181 ttttaagata atgcactatc aacacactct taagtttgct tctaagtctt atttccataa
      241 cttcttttac gtttccgcca ttctttgctg tttcgatttt tatgatatgg tgcaagtcag
      301 cacgaacacg aaccgtctta tctcccatta tatctttttt tggatatctg tcaactggta
      361 tggttgacag atatcctttt tttgttgtta tcacgtcctg ttcttttact gactgttgct
      421 tcaaaatctg cttgtgtcgg tctgtcagtt tcgcatggtc gagaatgtct tttacaacct
      481 gcgtctggtt gatttcatca agtttaatcg caacctttaa ggtcggggca acttgatgag
      541 atagccagtt cagcgtcctt tggaaggagt aaggctctgg ttttgtggtt agttttaatc
      601 gttcacgatt gttcccaata aaccaagccc attcttcatt cagtttccaa tcagaacgag
      661 gtttggaatc gtctttatct acaaaacgga tataccgatt gataatttta aaggcggtat
      721 gctctggatt gtcatagacg agtaaatcac ggactgcata ataggcacgc tcatttttca
      781 atcgaatctc aaaacggttt tttacttctg cgtcttcaat gggaatatca tttttcttgt
      841 actgctcgta gtccttttca tagatacaga aataaacttc actttgtaat gaaccgatat
      901 agagggtgtt tcccatacat tccttttcct ctttgcgtac cagttcgcca ctgcgatagc
      961 ttttaaaact gcggaagacg gagatacatt cttcctgttg gcacttttca gtgagtacag
     1021 ggatattcaa aatccctgtc ttatcgttaa tggcaaggtc aaggcgtttc atcacaccgc
     1081 cagccaccaa aacgtccata aagaactcat accagcttct ttgttgtgcc agaagatagc
     1141 tttcaaattg tctgcaccca cgacctttca attccaccag aactcctttg tccagttcat
     1201 gggagcaaag gacgaatatg tcgcctaaag cataatgctc tgaataagaa tagaaaccat
     1261 agtcctcatg aagaaaatag gacagtttca gttgtaagat gttttcgacc acctgctgta
     1321 cgtctgttgt cggaaagcga atccttacat aatcaaacag catttcaagg ggagcgtcgg
     1381 gattgaagcg ttccagagct tcccaaaggg actgctgtaa atcctctgat ggcttgactt
     1441 ttcctgtttc aatatcgctt agatactgcc ttgtaatacc agtcgcaaca gctaaacggt
     1501 tttgagatag tccataagcc aagcgttttt cttttaaatg ctgtaaccaa gtttgttcat
     1561 tcagtaaaaa tccctccaat caaaaaggcg tatgtcaact tttaaagccc atttgacata
     1621 cgctgaaatt ttgtaaatcc cttgtaacca aaggattttc taatgttttt ttgactgttt
     1681 cctgtcgatt tgtacccccc tgttagatac ggggggttaa gtgctggcgt ggctattgcc
     1741 acaccagcca gcaagatcag tccacacctg cgacttccgc ttcgcacgtc gcctgcgtgg
     1801 actgtctgct gttggataac tttttaattt cctccaagaa atcatatcct tttggtacaa
     1861 ggggagtata aaactctgat atgacacttg ttcctacatc aacatagcca cgacctttga
     1921 ttcgctttaa gaagaaatcc ttttgtacgt cactgccaaa catcatgcca tagcccattt
     1981 cagacatacg acctaaagcc actctgaaat taaactgatc acggattccg tcgcctaaat
     2041 attttgcgtc tggacgttga caagccagta ttagaaagaa gccagcttga cgacctaaca
     2101 tgacaatctg tttcagctta ttcataactg cggtgttttc ttttgttccc agcatttcca
     2161 tgaaagcgac gtattcatca aagattaaga agtgtgccgg gagacctaag taagcataat
     2221 ttttgccagt cttatagttc ttcatctgct tcatttcctc actacgtttc atcatttctt
     2281 catagaatgt ttcaatgcaa gaaagcaagt cttcttttct atagtagaca tttgccatca
     2341 cagaacctaa gtccgcaaga tcagcatttt tcgggtcaag aatatacagt tttgaatctg
     2401 tatgaagcaa ggcttcaatc agtgtcagta taaagtaagt tttaccgcca cctgtaccac
     2461 cagcaatcaa catatgaggg agcttatcat attcccacca tacgtttttc attaagcgaa
     2521 gtttaccatc tttagcttct acttcatcaa tagaaatacg actggctatg gtgtcataga
     2581 gcaaagtata ttccacatag gaatccttta actctttatc cgtcagctca cagtacaagc
     2641 cactctctaa tttcttttcc aagtgtaaga gttggtcttg atattttccc agcgtgattt
     2701 ccacccgtat ctgtatcaag ccatttttaa gtcgataata cattttaggg aagtaggtta
     2761 tcttttcctt tgtacgacca gcactatctt taaagaaacc ctctgttttg acctgttcag
     2821 attcatacca cttgttttca agtatcatct ttgccagttt ttgacggtgg taaagttgtt
     2881 taaccgtatc atagcgaacc cgtttgaata caaacgctac cagcaagcag ataagaattg
     2941 cgacactgaa actgataatt aaatagggaa tgtcaatctt atctgcttgt gataggttaa
     3001 aatcctgcca gttgatctgc tggattgtct tcacatgaaa cagtccgaca accagcagga
     3061 aaacaggcag gagtgacgct atcgtaaaat gaaagactaa atctttacca gatgggcgaa
     3121 tccttttacc acgctgtttc atgcgaaaaa gtctcctttc tacctagcga ctatttgtct
     3181 tgtgtcggtt ctttctttgc ttgtggttga gctttgaatg aactagaatc ctttgtcagc
     3241 acaatatcgt ctgccttgat ataccagtca acatctgctc cttgataggt ggcagtagca
     3301 acggtgtccg caatgggatt gataagttcc acccgtgcgt tataatcaaa ctctttcaaa
     3361 ggcacgctgg caggaatact tacttgaatc atgcgtcctt gtcctttgga ttttaagtca
     3421 taggtacgtt ccttgatttc atctgaaacc gacccgtctt cattttggat tctcacttca
     3481 cgacgtagag cagagaattt caattctcca aaagtcgtgt ctttatctaa tacaatgcca
     3541 tttgctaatc tcatcatttt tcctctcttt ctttattctt ttatcatgtc gtcagcatgt
     3601 aaaaggtaat ttgtaaaacc acgagtgccg attttgtagc cctctgcggt aatacgtgga
     3661 ttgactaact tcacacgttc ctcaaagccg aaatgttttt cgccagcttc agcaggaagc
     3721 accaccacaa tatcatctgc tctttgaaca tcagaataga gattatagct tcttgataag
     3781 acagttagcc gtccgttgat tcttcgctga acgactttat cctcgccagc aaattctaaa
     3841 ttgccgaatg ttttttccat gttgggaatc acaaatttaa gttccatatt tttacctatc
     3901 ctttcttttt tattggctga atgaatgttt gatggtctta aagagtgggg aacgaccttt
     3961 tgattcttga ttttttgttt tcataagttc acttcctttc aaaatcgggt aaaaaaatag
     4021 acacctcatt ttttgaagtg tctacctatt aaatattcaa attttattgg aagtatcttt
     4081 atatcttcac ttttcaagga taaatcgtcg tatcaaagct cattcataag tagtaaatta
     4141 gtagtaaatt gagtggtttt gaccttgata aagtgtgata agtccagttt ttatgcggat
     4201 aactagattt ttatgctatt tttattttaa aaaaactaaa tgaattgatt ttaaagaaat
     4261 aaaatgctaa catatatagt aagtgttagc attttatttc taagaaagga gaatgatatg
     4321 gttgataaaa gagagaaact gatgaactct ttcaatcagt atggtttttt aacttttaaa
     4381 caagtaatag atgaaaattt acactacaaa accttattaa aaatggttgc agaaggaaaa
     4441 atcgatgctg aagaaaaagg gttatatcgc ttacctgata tttatttaga tgagtggttt
     4501 gtccttcagt atcgatttcc aaagggaatc ttttctttgg agacagcact ttggttacat
     4561 ggtttatctt tgactatccc ttttaatatg acgatgagtt ttccttatgg tacgaatacc
     4621 aaaaacatta aggaagcaga tatatgtcct attattttac gctctcacta tagtgaagga
     4681 attattgaaa ttgagcgcct tcctggtcaa tttattaaag tttatgaagt tgaacgagtt
     4741 ttggttgaat gtctaagacc agttcatcag gtggatcttc aaattattgc accagcgttt
     4801 aaaaaatatt ttcaacaaaa taaaattcat ttacacaaat tattttatta tgcccagcta
     4861 tttaaagtaa ctgataagtt acaatcttat acggaggtac tatcttaatg ttttcaaatg
     4921 cgaatagctt taaagcaaaa atcaaaaaca tttcaaaaga taagggaatt ccagctcaac
     4981 aagtacaaca acattattta attgagcaag tattaaagct gatttctact agttcttata
     5041 gagattcctt cattgtaaaa ggagggtatc taataggtca aatgattgga ctagataagc
     5101 gaaccacaat ggatttagat gtcactctga agggaaccga aatgagcaga gaaaatttga
     5161 ttcatatctt tgaagagatt ctttgttcta aaactgatgg attttcattt tcagtagata
     5221 agctagaacc tattcgccaa gatgatgaat atggaggatt ttcattaaaa ttaaatgcaa
     5281 cttttgatac attaaaggag gttgttttta ttgatattac tactggtgat aagattacac
     5341 caagagaaat tacttattca atgacttcta tctttactaa tgaaagtatc aagatatgga
     5401 catataatct agagactgta cttgctgaaa agttagaaac gattatcagt aggggattag
     5461 cttcgacacg cccacgtgat cgatatgatc ttttcacctt gtataaactt agaaaagaag
     5521 agattaatct agaagtatta aaaaatgcac ttgagaatac ggcagaaaaa cgtaaaagta
     5581 aagatactat ttataattgg gaagaacaag tgagaggaat tgaaatttct gattatcaga
     5641 aagagctatg gattcgttat caacgccaat ttaagtatgc taaagatatc tcatttgata
     5701 actctgttca ggtcattagg gaaattatgc aacaaatatt ttagtacaaa agcaactcat
     5761 tcgtaaagca gtgagttgct ttttttattc caacaacccc aaaaatgtga taaaaatttc
     5821 aactactctt atctataata aagctacctg ttctttgaaa attgaatcca ctccgtcttg
     5881 attagcgtgc ctgtgtaagt agggactgag agtatttccc tgtgaagggc aactggcaca
     5941 agacgtgtgt gagaattttc taacagacac ggagtttatc gttaccagac ttaaacgatg
     6001 cgacaaacta gataaaggag ttaatcatga aggtagtaaa cttgtatgat ttgaaacaaa
     6061 tgggaaataa aggtggttgt accatccaat tgattcatca ctttcctttt ggtatgggct
     6121 taggacatct caaaaaagac tacattgaat ttaaacgtgt tggtatcgtt gatgggaaag
     6181 cagtagaagt tactcttcga gaaccttatt cgagagatct actgcaggtt gtcaagtcga
     6241 ttaagcaacg tcagaaattg atagcttatc gttataaaga aggaaagctg ctatttgtta
     6301 aggaggaggc atcagatgtc ctctgaacaa caggaacgaa tggcggttca atatgcagag
     6361 cgtagtcttt tatttactgt aaaaagtctc ttaaagattc tagaatggtc tagacgtcag
     6421 gctttagcac aggattccgc ctataaaata ggggtacaga aattagaaga attgctacaa
     6481 tctccttatt cgattgatac gattaatctg aaaaaagatt ttttagacaa accaattgat
     6541 atagagaaat ttaaagcttt tttagaaaaa gaagagattc ctttagccat cgcttggcaa
     6601 ggggattctc tgcatttcta tacgaaagac cgttcgattc tggacaatca tttagaccaa
     6661 ctgttagaaa aaatggttaa tgatccagag aaattagctg attttaccat ggataagtca
     6721 ttagacgatg caattgatga ggctaaatcc caaattacct ttagacaaga aggagccgtc
     6781 aaacagaaag agatggtgag atgatgtaca gtggaaagaa attcctacta ttctcactgt
     6841 taggtatctt actaggttat ctttttcatc gtttgacgct tttgtatgat tcctatactg
     6901 gaaatagctt agataaatgg actcatcttc taatggaagg tcaagatgaa gttcttcagt
     6961 cgccatggaa tgtttccttt actggaaaat ccagtgcttt ttttctacta ggctttgtga
     7021 tgatgttgct ggtttatctt tatttagaga ctggcaaaaa acaataccga gaagggatag
     7081 aatacgggag cgcccatttt ggaactctaa aagaaaagaa gctcttttac ggcaaggaat
     7141 tttctcatga tacaatctta gcccaagatg ttcgtctgac attattagat aaaaaaccac
     7201 cccaatatga tagaaacaag aatattgcgg tgataggagg ttcaggaagt gggaagacat
     7261 ttcgctttgt gaaacccaat ctaattcaga tgaatagttc taatattgtg gtggatccta
     7321 aagatcactt ggccgagaaa acaggcaaac tctttttaga acatggctac caagtaaagg
     7381 tgttagattt agttaatatg aagaactcag atggcttcaa tccttttcgc tatatagaga
     7441 cagaaaatga tttgaatcgc atgctgacgg tttattttaa taacaccaaa ggctctggat
     7501 ctcgtagtga tccattttgg gatgaagctt ctatgacttt ggtacgagct ttagcctctt
     7561 acttggtcga tttctataat ccacctaaaa caagagaaca gctcattgaa gagagtcgtt
     7621 taagtcaaaa agaacaccaa aacttgttga aacgtcaaaa aaaagaagtg gaagagcgaa
     7681 aaaaacgagg gcgttatcca agttttgctg aaatctcaaa actcattaaa cacttatcca
     7741 agggtgaaaa ccaagaaaaa agtgtcttag aaattctatt tgaaaattat gctaaaaagt
     7801 atgggactga aaattttacc atgcgaaatt gggcagattt ccaaaattat aaggataaga
     7861 ctctggattc tgtcatagct gtaaccactg ctaaatttgc cctcttcaat attcaaagtg
     7921 tcatggattt gaccaaaaga gatacccttg atatgaagac atggggcaag gaaaaatcaa
     7981 tggtttactt agttatccca gataacgata gtacctttcg ctttctatca gccctctttt
     8041 tttcaaccgt atttcaaacc ctaacaagac aagcagatat tgattttaag ggtcaattgc
     8101 ctcttcatgt gagagtttac ttagatgagt tcgcaaatat cggagaaatt cccgattttg
     8161 ctgaacaaac ctcaacagtc cgttctcgga atatgagtct cgttcctatt ctacaaaata
     8221 ttgctcaact tcaaggactc tataaagaaa aagaagcttg gaaaactatt cttgggaact
     8281 gtgatagctt agtctactta ggtggtaatg atgaagatac ttttaaattt atgagtgggt
     8341 tactcggtaa acaaaccatt gatgttcgaa atactagtcg ttcctttggc caaacaggtt
     8401 caggatccct ttctcatcaa aagattgctc gtgatttaat gacacctgat gaagtcggaa
     8461 atatgaaacg gcatgaatgc ttagttcgaa ttgccaatat gcctgtcttt aaaagcaaaa
     8521 aatacaattc cactaagcat ccaaactgga agtacctagc caatcaagaa accgatgaaa
     8581 ggtggtggga ctatcagatc aatcctttga atcaaagtca ggaaaatcat cttgaaggcc
     8641 ttagaattcg tgatttgact tttgaatcta gtttaaaata aaaatagaaa agaggaaata
     8701 gatgattacg cattttaaag gttttgttta tggagtagac gcaagtgcta tgtttgcaca
     8761 agctatgtct ttgttacaga agggattgat tgcggttggt gcctttctcg ttgttgttgg
     8821 gattgtcaat cttgcaacca atattaaaga tggtggacca ggtgttcgga atgccattct
     8881 tgaaattgtc ggtggtgtta tggtcggggc tgctggagcc tttgtaactc aaatttcaat
     8941 ttaggaggat aaacaatgac atgaatctta gtttagtctc accctttgtt taccttgcat
     9001 ctgaaaaaat atcagctgaa aatttatttg aaggatttag tgtggattta caatctacgg
     9061 tagatctgat taaatctcta tctagctaca atccaacagt ttggacttat atgtctagta
     9121 ttactaaaag cgtcatgcag cctcttggag ttgcgatttt atcagttgtt ctcatcttag
     9181 aattttcgaa gatggcaaag aaaattgcta actcaggagg agcgatgacc tttgaagcat
     9241 tagcaccgat gttgattagt tatattatgg tcgcagttgt aattaccaac actaccgtga
     9301 ttgtagaagc catcatcggg attgcgagtc acgccattga gcaagtggcc tcgattgtgg
     9361 ctcacggtgg ggcaaagtat gataccatct ctggattaaa agggtcagga tttattggcc
     9421 ggatgattgt gggctttttc gccctcctca tttggcttgt tcggatagta agtgctgcca
     9481 tggttaatct tttggtatct attcgattta ttcaactcta ccttatgatt ccatttgccc
     9541 ctcttacgat tccaacattt ttaagtgatg aatggaagtc tattggtatt ggctatttaa
     9601 aaaatattat ggtctatgcg gtacaagggg ttcttatttt tctgattgtt tctcttgttc
     9661 ctttgtttga atctgctggg aaaatagctg tttcaaatgg tgcaggagtc ttgcaatcac
     9721 ttgcgattat gtttggtagt ttggtacaag ctatcttact gattattgcc ctcgttggtt
     9781 ctcaacgtac ggctcgctca atcttaggta tgtaattaga taaaggctag gaagtgattg
     9841 cttcttagcc tttttagaaa ggaaagtcat gaatacacgt gtctttaaag acatctcaaa
     9901 ataccaacac agggcttggt taggcttcac tacaaggcaa atcatctttg ttttaccagc
     9961 ctttattgtc acaattattg ttttgggctt gaatctcttt ttctggcaat ttggagattg
    10021 gtttgtttac ggttttgtgt ttgcctttac catccccctc atgctttttg gagtctataa
    10081 acccaatgat ttatattttg aacattattt gaaataccgt cttcattttg aattaacggt
    10141 tcccctacgc acaattacag gaaagaaagg acatgaacat gaaaagaaaa tcaaatacat
    10201 taaagaaaca aaaagcttca atgacttata aaaaggaaga agttaaaggg aaaaaagagg
    10261 aagtgttacc ctctacggcg aataccattt cctatcaagc cctgtatcaa aatggtctaa
    10321 tgcaggtaaa agaagattat ttctcacaaa gctacttact tggggatgtc aattaccaaa
    10381 ccgttggttt agaagataag ggggcaatca ttgagaagta ttctgatttg attaactccc
    10441 tagatgacca aaccaacttc caattgacca tctttaataa aagattgaat ttagaaaagt
    10501 ttagacaaag tgttttgtat gaggaaaaag aagatggata tgatacctat cgtaaagaat
    10561 tgaatcggat gatgaatcag aatttagaca gtggtgaaaa taatttttca gctgtgaaac
    10621 tgattagctt tggtagaaag gattctaatc ccaaacaagc ctatcgttcc ttgtctcaaa
    10681 taggagaata tttcaagagt ggtttttcag aaattgatgc acgttttgaa tccttggctg
    10741 gagaagaacg tgtcaacttg ttggcagata tgcttagagg agaacaccat cttccttttt
    10801 cttactgtga tttaacgaga tctggtcaga caactcgtca cttcatagca cctaatctct
    10861 tagattttaa aaacaagaat tacctacaga ttaatgaccg cttattgcag attgtctatg
    10921 tgagagacta cggcatggaa ttaggggatc agtttataag agacctcatg caaggagatt
    10981 tggaattgat tgtgagtctc catgctcaaa gttcgaccaa ggcagatgct atgaagaaac
    11041 tacgaacaaa gaagaccttg atggaatccc aaaagattgg ggaacaacaa aaactagctc
    11101 gtacaggtat ctatttggaa aaagtaggtc atgttttaga aagcaatatc gatgaagctg
    11161 aggaactctt aaaaaccatg acagagacag gagataaact gtttcaaaca gtcttcttga
    11221 ttggggtctt tggtcaggat gaagaagaac tcaaacaagc actagacact atccaacaag
    11281 tggccggatc aaatgaccta atgattgata aactaccata tatgcaagaa gcagccttta
    11341 attgtttgct gccatttggt tgtgattttt tagagggagt atcacggagt ttattaacgt
    11401 ccaatatagc agtgaactca ccttggactt cagtagactt acaagaccgt agtgggaaat
    11461 attatggtat caatcaaatc tcaagcaata ttattaccat tgatcgcagc ctattaaata
    11521 caccgtctgg tctgatttta ggaacatctg gagctgggaa agggatggca actaagcatg
    11581 aaattatcac gaccaaaatc aaggaatctg gtgaaaatac tgaaattatc atcgtggatc
    11641 cagaagcaga atacagtgtc attggacgag cttttggggg agaaatgatt gatattgcgc
    11701 ccgattccca aacttatctc aatgtccttg acttgtctga ggaaaatatg gatgaggatc
    11761 ctgtaaaggt aaaatcagaa tttcttttat cctttatcgg taagttattg gatagaaaaa
    11821 tggatgggag agaaaaatcg attatcgacc gagttacgag actcacttat cagtcattta
    11881 aagagccttc tttggaagaa tgggtctttg tcttgagcca acaaccagaa gaagaagcgc
    11941 agaatttggc acttgatatg gaactgtatg tcgaaggttc tcttgatatt ttttctcata
    12001 agaccaatat tcagacagga tctaacttct taatctataa cgttaaaaag ttaggagatg
    12061 agttgaaaca aatcgctctt atggtagtgt ttgatcagat atggaatcgt gttgttcgga
    12121 accaaaaatt agggaagaag acctggattt attttgatga aatgcaactt ctcttattag
    12181 ataaatatgc cagtgatttc ttctttaaat tgtggagtcg tgtcagaaaa tatggagcca
    12241 gtccgactgg gataacccaa aatgtcgaaa ccttattgtt agatccaaac ggtagacgga
    12301 ttattgcaaa tagtgaattt atgattctcc taaagcaagc aaaaaatgat cgagaagaat
    12361 tggttcaact cttaggattg tcaaaagaac ttgaaaaata cctagtcaat ccagaaaaag
    12421 gtgcaggact gataaaagct ggttccgttg tagttccctt taaaaataag attcctaaag
    12481 gcactcaatt gtttgatatc atgagtacag atcctgataa aatggcttct aattaagggg
    12541 aaggtaaatg aaggataaaa gagaaatcat acgtgcccga aaggcattta gaagaagtct
    12601 aaaagatgag aagaaattct tgaaaaaagg aaagaaggag gtgaagaaac agaaaaaaga
    12661 ttccgctgta ctggatgaaa aagcatggaa aaaagagata aagaaaaagc tagaggagat
    12721 gagagaagct tcaaaggcta gagtaaaaca agcaaatgaa gactacaatc atattcttca
    12781 aaatagtcct ccatctcttt taaatcgcaa agaattaaga gacagacgat tacctcatgc
    12841 taggaaacga ttgaaaatag caaagaagca atatagagaa gccaaggtag aagcaaaaga
    12901 agaaagaaaa gagagtcgta aagaaagaaa aaccaatcaa aaatttcttt atggtcagga
    12961 atcgaaagca aaatccaatt ttttctttca agggaagagt ttagaagaat taaaagttaa
    13021 gaaagaagtc aagaccgcaa aagagaatct aaaatctact aaacaagcct ataagtccaa
    13081 aaaagtcagt aggaaagcca aaacttttct ttatgtcctt ggacgtgaag gtggagagtt
    13141 agcttcagaa aatgaagatt tagatggtta tcgcacactt caagagacaa ttagaaaagg
    13201 gaaacgctac agtcgccttt cttataacct tggaaaagct agtgtcaaaa caggacaagc
    13261 aacatgtcgt tttaccaaga aaagactgac caacacaaaa gagcgatacc atcattttaa
    13321 ggatggaaaa ggatggaaac tagcgaaaga taagccaagt tcctttaaaa atcggtttcg
    13381 aaaattaaag aaacaaggtc ttacaagtgt ccgaaatatc tatcaaaaac taaaagcagc
    13441 cttttccttc tttacatttg cggctggaaa tcctgtaacc tggatagttg gaggaatagt
    13501 ctttcttctt ttacttataa tgagcttctt tttaggattt tcatctgcta gtttgattca
    13561 acaagatgaa tttgaattaa caaaagctta tacccaccta acttgggaag acgcagaaca
    13621 tactcgtaca aatgacaaag gaattaccta ttacacaaaa gttgatgatg tgatggggta
    13681 tatgaacttt aaattccatg actatgagtt acacaaacca gttcacttat ttagttcaga
    13741 aacttacaag gattatctat ctactttgtg gcatgattta aacgatgggg aagatttgaa
    13801 atccatgcaa gacctctatg aaactcctaa gtataaacta tcgaaagacg atcaagagga
    13861 aatgaaggaa ctaaaagaag aaggtatcta tgcttccatg caggaattgg acaatccatt
    13921 tgaagggaaa agtaacgaag atagtttgac catgacttat cgttacggat attatgatct
    13981 agacggaaaa cctacccttc aggagtacat tctactagaa gcaaaggctc accaaacaat
    14041 tgtcgcacca atggatggag ttgtatctct agatggagac aatgttattc tcactaacgg
    14101 aaaaggagag aatgagagtc gattgacctt gtattctatt cataatggcc gtgcgattga
    14161 gggaacaaga gtcctaacag gtgatattat tggtgaaaca ccagacgata caggtttgaa
    14221 agtttcctat caaaagtata agaacaagaa agaaaaattg gtgtatgtca atccgcaatt
    14281 ttattttcca aaagtcattc aacttcagac cactatctta ccagccattg gtcagtttgg
    14341 tggggatgag tttgaacgag caaaacatat ttatgagttt ttgaaatctc aaggggcaag
    14401 tccccaagcc attgcggcta ttttaggaaa ttggtcggta gagtcttcta tcaatcctaa
    14461 acgagctgag ggagattatt tatctcctcc agttggcgct accgattcct catgggataa
    14521 tgaaacctgg ttagcgatag gaggaccagc catttatagt ggtgcttatc ctaatattct
    14581 tcatagaggt ttaggtttag ggcaatggac ggatactgca gatggttcaa cacgtcatac
    14641 agctttattg aattatgcac atagcaaaaa taagaagtgg tatgatttag acctccaact
    14701 tgattttatg cttcatgggg atagtcctta ctatcaaagt tggttaaagg atttctttgg
    14761 aaatacaggc agtgcagcca atctggccca actcttcctc acctattggg agggaaattc
    14821 tggtgacaaa ctactggaaa gacaaaccag agcaacggaa tggtattacc aaattgaaaa
    14881 aggctttagt caaacaaatg gaggacaggc aaagagtgat ccacaatccc ttgaaggggt
    14941 tcgtggggac ttgtatgatc attctgttcc tggtggtgga gatggtatgg cctatgctta
    15001 tggacaatgt acatggggtg ttgcggctcg tatgaaccag ttaggcttaa aattaaaagg
    15061 tagaaatgga gaaaagattt caatcattaa taccatggga aatggtcagg actgggttgc
    15121 gacagcttca agtcttggtg gagaaacggg ttccacacca aaagcaggtg ctattgtctc
    15181 ttttgtagga ggtacacatg gtacaccagc tatatacggt catgtggctt ttgtagagaa
    15241 ggtctatgat gatggttctt tccttgtgtc tgaaaccaac tatggtggca atcctaacta
    15301 tacctttaga aaaatctcgc aagcagatag cgccattagt tttgcctata ctacgaaata
    15361 gaagagttta tacttgaaat tttaaccatt ttcaggtaga ataaatagtg tagatgagta
    15421 gtcggctcat ggtcaatctg atagtaatct tggacataag ggccaagcgg tggcggacac
    15481 cagaacgaaa tccgatagca atcttggacg taagggccaa gcggtggcag acaccagaat
    15541 aaaccgactg actaggtggc ttacagactc tgtaaaccac cttttttgtg aggaaaatat
    15601 ggcaaattct agagattatc gtaatccaaa ttacaccgaa aaaataaaac ttcagcgttt
    15661 ttttactcag ttacaaattg cagcttcttt ttttaaagaa cacttcgttg gcaaaatcat
    15721 gtattatgaa acagaaatag aaagtgttga acttcatttt tcacctacta atttcatgca
    15781 cctatgtggt gttgattacc gaaaaggtgc aggcagtttc tttgacgatt gtttaaatag
    15841 gcatgtcata attgatgagt tgaaaataaa aaaagatgga accacaatgc aaaagttaca
    15901 agttttagga tccattgagg agttattggg aaagcatgtt catctaactg gttcaggacg
    15961 ttatttgtat ttggagtttg attatgcttt acgtacaaga aaacagatac tagcattaac
    16021 attgaaagag acatcaagga aaattgttcc tcaatcttta ttagatttga agagaaagac
    16081 agtatttcca aaaggtcaaa aagtaatttc aatttactca aaacatttac aaacgtcgga
    16141 acttttttat tatttaaaag attagtttac atatcttttg tggcataaaa tatattttta
    16201 tcattttcag gagaacgcag ttttggctcg ttctcttttt ttgttgtgat acttctttca
    16261 aggaatattt ggtaggattg gagtgaaaaa agattaacta ggaaagaagg aagtatatgg
    16321 aaggcattta tcaacgtgat tcggatcaag atggattaac tgatgctcaa gaattggcgc
    16381 taggaaccaa tcctcttagc gcagattctg atggtgatgg acgttcagat ttagtggaag
    16441 tagaagaagg aaccaatccc ttagaaaagg atttacaaga catagaccaa acaagtataa
    16501 ctgaaccgtc ttcagtattt atggaaatga aacaaaagat ttcagatatg atggagagtc
    16561 actacaagga atttatacag gctcttatta gtattgaaac agggattgaa aacgaacaag
    16621 acctagaaga cttatatact tactacatga gaacagattc tatttctctt ttgtctagtg
    16681 atttagaaac cagtcctcaa aaggttgaaa tggagataga gttgtagggg aatcatgtga
    16741 ttctcctatt ttcgtataga tgaaaggagc gagtatggaa gtaatgaaat tattggctat
    16801 gtttcgtgga acaattccaa aagataggga gaaaatggac ctatttcttc gttatcaagc
    16861 gcaacatttt gatgagaaat ggcaggactt ggtagagagt tttttggctg aagagggcaa
    16921 gatagaagag atacctcatg tctattcgtt tcatcaagat attatttctt tcctagaggc
    16981 tagttctgaa aataatgacc aagatttaga aagttacaca agaaattttg gacaagcagg
    17041 tctaagtaaa ttatctcaat taagtaattt tgagaaaaac ttggtgctag aagtcgcaac
    17101 ctataatctt tccactcgat tttacatcca atctgaaaaa gagaagttag aaccattaag
    17161 tgaacttgta tgtcttcaga atcaggatgt caatttagtc aatgtctatc gggttgcgaa
    17221 taatctatct gaccgcatta gtagagatat agaggagttt cttctaatgg ttgattccaa
    17281 agaactaaca aaagaagttc ttgagattca ttttgaagaa aaagaaggag atgttctagc
    17341 ttatttgggt tcagaattga tggctacttt agatactgtg acggatcttg tccatcatga
    17401 agaaaactac acacaactcc cactgacaca aaagctgaag attattactc attttgatga
    17461 tgtaaaagct agaagcgaaa agtctaatca agtagaggaa gttttatctc cttcaagtga
    17521 tattgaacag gaaacggaag aaacgaactc tttttctaat gtcgataaaa ttgtagaaga
    17581 agctttgagg gaatatccaa tcggttcaca agtaagttat aaaggacaag tttttcagtt
    17641 ggtttcgatt gaaaatgcac agttaaatga cttaattcgc ctagaactat tcaatgattc
    17701 caaccagtta tttgaagaaa atcctatctt atacttgaac agtttggaag agattgaaca
    17761 agtattgtct cttgtagaac ttgaaaaaga agattcagag attgagattg attcatcaag
    17821 tgaaagtcag gaaatagatt tgttttccta cctggaagaa gaaaaagaaa atgaaaagga
    17881 taaggaaaca gaaacgctta ttgtaggcat agaagagacg gatgtccctg ttcaagattt
    17941 tgtttttcca gatgatttag aggactttta tcctaagaca aatcgagaaa agattgaaac
    18001 gaatatcgcc gcaattgaac ttgttaaaag attagaaaaa gagggacgac aagcgaatcc
    18061 agaagaacaa gaactactag ccaagtatgt cggatggggt ggccttgcca atgaattttt
    18121 cgatgaactc aatccaaagt atgaaacaga acgtttaact cttaagagct tagtaagtaa
    18181 atcagaatac tcgaccatga aacaaagttc tctcacagcc tattatacag acccaatgat
    18241 tattcgccag atttggcaaa aattactgga tgatggtttt gagggaggaa ggatattaga
    18301 tccttctatg gggactggga acttctttgc ggcgatgcct agaagtatac gagataaatc
    18361 agaactctat ggggttgaat tagacagtgt gacaggcgca atcgcaaaaa aactccaccc
    18421 caatacccat attgaagtgc gaggatttga agaagttccc tatcaaaata atagttttga
    18481 tttagtctta acgaatgttc catttggaaa ttttcgcatt gccgataaaa actatgataa
    18541 accttatatg attcatgatt actttgtcaa acactcactt gatttagtaa gagacggagg
    18601 acaagtttcg attatctcat ctatcgggac aatggataag cggacagata atgtcttaca
    18661 agagattaaa accaacactc attttttagg gggagttcgg ttgccagata cggcttttaa
    18721 aagcattgca ggtacccgag tgaccacaga tatcctcttc tttcaaaagg atcaagcaaa
    18781 gaatcttaat gaagaggaac ttgtttttag tggctctatt ccctttgagg aggataagcg
    18841 tgtctggatc aatccttatt ttgatgggaa atacaacaca caagttttgg gtgaatatga
    18901 ggtacgtaat tttaatggag gaactctcaa tgttaagggg gtatcagaaa cattatctac
    18961 tgatataatg aaagcattag agaatgtgga agcacctaaa caaattgaca attttttgaa
    19021 agcacctgtt tttatccaag aagaagtgga taattcgctc ccaagtcgta tacgtgagga
    19081 cttagcgctc tattcttttg gatatgagag aaatcaaatt tattaccgag atacgcatgg
    19141 cattcggaaa agttcaaaag tagacgaaat tagttattat gtagatgaaa agggagattt
    19201 taaagcttgg gacagttctt tgtctgaaca taaaatagac cgattcgtgc aacttcattt
    19261 gacagatgag gaagcactag atgtttacaa gtcagaagaa gcgagtaaaa gagggaaata
    19321 taagggactg ttcaaaaaaa ctgtctttta tgaaagtccc ttatcggata aggatattag
    19381 tcgcattaag ggcatggttg atttgagaga gacctatcaa tccttaattg aaattcaacg
    19441 ccatcaagat tatagtcgga cagattttca ggtgttactt agtaaactca atcataacta
    19501 tgaccgtttt gtaagtcaat ttggatactt gaatgcctca gtcaatcgga acttatttga
    19561 tagtgacgat aagtattctt tactggcaag tttagaagat gaatacattg attctaaaga
    19621 tcagaaagta aaatataaaa aatctttagc ctttgagaaa gcattggtta ggccagagag
    19681 agtgattgca agagtttcaa cggctctaga tgccttaaac tctagtttat cggatggtag
    19741 aggggttgat ttagactata tggtatccat ttatcccgaa catagccaag ctgctatttt
    19801 agatgagtta ggagaccaga ttttaataga tccagaaagc tatttaagag gggaaagaaa
    19861 atatctttct aagaaccagt ttttatcagg agacattctc aacaagatag aagtagttca
    19921 actattagtg gaggaaaaca accaagaata tgattggaac catgctttag atttgttaga
    19981 atctgttcgc cctccaagga ttcatctggc agatattgag tttaaaatag ggtcacgttg
    20041 gattcctcaa tccgtttatg gtaaatttgc ctttgaatgt tttaccaatc gtgaatttga
    20101 attatcttcg cctgatgttg aacaggtcat tgaagcgaat cctgtcgatg ggcaggttca
    20161 tttaaggaca tcatttgctt atcgctatcc aagtgccaaa gatagtagtc ttggagtcag
    20221 tggctcacgt tatgatacag gaagaaagat ttttgagaat ttacttaatt cgaaccaacc
    20281 gacgattact atgactgtta cggaaggaga aaagaaaaag accatcacag atttggaaaa
    20341 aacctctgtt ctaagagcaa aagaacagca tttacaagag ctctttcaag actttgtctc
    20401 acggtatcca gaagtccaac aagtcattga agaaagttac aatcgtcttt ataaccgaac
    20461 ggttagtcga gagtatgacg gtagccatct agtcattgat ggcttagcac aaaacatcag
    20521 tcttcgtcct caccaagaaa atgccattca aagaatcgta gaagaaaaaa gagccctatt
    20581 agctcatgag gtaggttcag gaaagacctt gaccatgctt ggtgctgggt ttaaattaaa
    20641 ggagttgggg atggttcata agccattata tgtggtgccc tctagtttgt ctgctcaatt
    20701 tggccaagaa atcatgaaat ttttccctac taaaaaagtc tttgtgacca ctaagaaaga
    20761 ttttgtgaag gcgagaagaa aacaatttgt atcacgtatt attacaggag attacgatgc
    20821 tattgtcatt ggggattctc aatttgaaaa aatccctgtc agtaaggaaa gacagatgaa
    20881 ctatatagag gataaactca atgaactacg agagattaaa acacattctg aaaataagta
    20941 taccgttaaa gaagcagaac aatcaataag tggtctagag aaacaattgg aagaactgca
    21001 acgctttaat cgtgatagtt ttattgattt tgagaactta ggaattgatt ttctctttgt
    21061 ggatgaagca catcacttta aaaatattcg tccaattact ggacttggga atgtagcagg
    21121 tattaccaat acaacctcta agaagaacgt ggatatggag atgaaggttc gacagattca
    21181 ggaagaacat gattttaaaa atattgtctt tgcgacagga acacctgttt ccaattctat
    21241 tagtgagttg tatactatga tgaactatat tcaaccagat atcttaaaac gctatcaagt
    21301 tgattatttt gactcttggg taggtgcttt tggagaaatt caaaactcta tggaattagc
    21361 tcctacaggg gataagtacc aacctaagaa acgatttaaa aagtttgtca atctacctga
    21421 gttgatgaaa atctataaag aaacagccga cattcaaaca caagatatgt tggatttacc
    21481 tgttccagaa gctcatatta tccctattga gagtgagtta actgaaaacc agaaactcta
    21541 tttagaagaa ttagttatga ggtcagatat ggtcaaatgt ggaacagttg atccgagcca
    21601 ggataacatg ttaaaaatta cgggtgaggc acgaaaacta gctattgata tgcgtttatt
    21661 ggactctagt tatagtctag cagacaatca taaactgctt caggtagtgg ataatgttga
    21721 aagaatttat cgtgagggaa tggaaaataa ggctactcag atgatttttt cagatattgg
    21781 cacacctaag aaaaaagata atggctttga tgtttattct gagattaagg ctttattagt
    21841 tgatagagga atccctagta aagaaattgc ctttgtacat gatgccaata gtgatgaaaa
    21901 gaagaatagt ttgtctcgaa aggtcaatgc aggagaggtg cggattctcc ttgcctcaac
    21961 tgaaaaagga ggaacaggtt taaatgttca gagcaagatg aaagcagttc atcatctgga
    22021 tgtaccgtgg agaccaagtg acattcagcg tgcgtccgta aaggcggtat agtaaatcta
    22081 ctcttggcaa agtagtaggc gtgaccttaa tgcctatcat cacccaactg acctgtgagg
    22141 gaaaccaagc atcagggaac aaagcacgtt gggaaactca taagttgatg agttatcaca
    22201 tcacgactga atgaggagat gataatgtaa cagatgttat tgagataatt ataaggataa
    22261 aatctaaact gattgaagga tagtctaaac ggtctgtgtc gggactgtga ggtaagataa
    22321 ctaaaatcct catactatgg aacttcatta tcactgttga agatagtgaa gcaaagggat
    22381 tccatagcgt attcatagta aatgaaaaca gatgaacgtc ctatccgatg aaattatcaa
    22441 gctatgttac tataccagct aaacggagat tacctaagtc aaaacgcttg taaaagctat
    22501 taaacataag gtttatgaat atttgataag gtaacggagt tcccatagta gtccgagcgt
    22561 gttaatggca cgtacatggc gaaggggaac agtttataac attaacatta tggaaaggaa
    22621 ggtgtgtgag acaccatgag aaatcctcaa aatgtgttaa acaatctaac aaaacacagt
    22681 aaagataaaa actatcaatt tgagcgactg tatcgtttgc tttataacaa agaaatgtac
    22741 ttagttgcct atcaaacgat ttacgctaac ccaggacact tgacacctgg agtagacgag
    22801 ttgacgattg atggtatgag tatagctaga attgaccaat tgattgattc cctgaaagat
    22861 gaatcctatc agccacaccc atcaagacga acctatattc ctaaaaagaa tgggaagcta
    22921 cgtccactag gtattccatc atttgatgat aagctcttac aacaggttat taaaatgatt
    22981 ttggaagcta tctacgaggg acaatttgaa ccctcttccc atggttttcg tccgaataaa
    23041 agttgccata cagcacttac tcagattcag aagacctaca ctggaacaaa atggtttatt
    23101 gaaggagata tcaagtcatt ctttgataat atcaatcatg atgtgatgat tcacattctc
    23161 cgagaaagaa ttactgatga gcggttctta cgcttgattc gtaaattcct caatgcggga
    23221 tacgtggaag attggaaatt ctacaaaacc tactcaggaa ctccacaagg agggataatc
    23281 agtcccattc tagccaatat ctatttggat aagtttgata aatatatgac ggattatgtg
    23341 aagaacttct gccaagggaa ataccggaaa cgtaccccag aatatcgcca aaatgagata
    23401 gcgttgggaa aagcaagaag agcattagaa tgtgtttcaa cggaaaatca acgacaagaa
    23461 gttatccagc gtattcgtca attggaaaag gaaagagtgt taattcctca tagtgatcct
    23521 atggatagta gttttaaacg tctaacctat acccgatacg cagatgattt tatctgcggt
    23581 gtgattggca gtaaagagga cgctcatcgc attaaagcag atattaagga ctatttggaa
    23641 gcggttctca aattggaact ctctgtggag aaaaccttga ttaccaatgc gagagataaa
    23701 gctaagtttc tgggatatca tctgtatatt cgccaatcga atttagctaa gcgtgattcg
    23761 gcaggacgat tggtaagaaa ttatacaggt agattagtcc tagaggtttc tattgaaacg
    23821 attcgagaca gattactgtc ttacggagct atgaaaatga cttatcatag aggctacgaa
    23881 gtttggaaac caacggcccg ttatttcatg aaagattgcg atgatttaga gattttagaa
    23941 cgctacaatg cagaaataag aggtttttat aactattatt gtatcgctaa taacagctct
    24001 atccttcatc gctttaagta catcatggaa tatagcatgt ataaaactta tgcgactaaa
    24061 tatcgtacga ctaaatccca catcatccgt aaatataaaa aggatggtca atttagtgta
    24121 cagtatattg gacgtaaagg ggatacaatg acccgttatt tatataacgg aggatttaaa
    24181 cgtcaaaaga aatctttcct tgaaaatgat aatttgccaa atacggcgaa atattttagt
    24241 cgaacaaatt taattgatag attaaaagca agccgttgtg agtattgtca agcgaccgac
    24301 agttccctag aaatccatca tgtgagaaaa ctaaaggatt taaagggaaa gactttttgg
    24361 gaacgtttga tgatttctag acaacggaaa acaatagcac tgtgtaaaga ttgccataag
    24421 aaattacatc atggcaagtt agattgagtt tataaacgga gagccgtata cattgaaagg
    24481 tgtacgtacg gttcgggggc gagtatttgg aaacctgacg tagtaatatg gtaaggcgct
    24541 gggtacttag cctacaacgc aatggacgta ttatccgaca gggaaatgaa aataaggaag
    24601 tggatattta ccactacatt accaaaggtt catttgataa ttatctatgg gcaactcagg
    24661 agaacaaact ccgttatatt aagcagatta tgacttctaa ggagccgatt cgtgctgcag
    24721 aagacattga tgaacagact atgacagctt ctgattttaa ggcactagca acaggtaatc
    24781 cttatctcaa atataagatg gaactagaga atgatctaac tctattagaa aatcaaagac
    24841 gcgcctttca acgcagcaag gatcactatc gtcatacaat ctcttactgt gaagaaaata
    24901 tgcccattct tgagaaacga ttaagcaagt atgaaggcga tattcaacag tctgaaatat
    24961 cgaaagacca ggcattttct atgagggtag gtaagcaatc ttttgatcaa cgagctgaag
    25021 caggggaatc cctacaccgt cttattcgtc ataatcaagc tgacagcaaa gaatttcgta
    25081 ccctagcaag ctatcgagga tttgacatta aaatgcttag tcttccaaca aatcaacctc
    25141 ttcctgaaac cttctctgtt aaaattgtag gagagaatca gtattctgtc agtttagatt
    25201 tatattctcc tttggggaca attcaaaggc ttcagcatac gattgatcac attaaagagg
    25261 accaagtgaa aactcagaac ttattggatg aattaaagga taaatggaat actgctaaag
    25321 ttgaaattga gaaaaatttt ccaaaggaag aggattatca aactaaaaag gccgaatacg
    25381 atgtactcgc gccattgatt gaaacagaaa cggatttaga tactattgat caggccttaa
    25441 gacaattcca cgaaaaagga aaagaaaagc aagaacaact ttcttttgaa ttagattaaa
    25501 aaatagatac aaatagcgga caagaaaaga aaagcgcggt aaaataaaga tagaaagaaa
    25561 cgaggtaacg attatgatgg aagataccta ttatcaatta gaagaggctt tggtacaggg
    25621 atttcaaaca cctgaagaat accaagccta caaggagtta aaggaacatt atgaggaagt
    25681 gacaggggat tacagctttt ccaaacgaga acttactagc caattggaaa tcgctcttca
    25741 gaatcatcga ggtgtggact ttgaagaata tgaaaaaaag gactatctgg aattggttca
    25801 aaaactagaa gagtttgatt cctctcttgc cacccattat cgtcaattga ttgactagaa
    25861 aggagaaagt catgaatgat ttactcctta tcccagtaat ttttttagca gtaggaggaa
    25921 ttctcattct tttatggaga ctctttctta ttgccagtgg acttttcttg attggttttg
    25981 tcagtttcct tattttcgtg gaggtctatg gaatttatct tctctttaca gaaactgaac
    26041 tttacacggc agatttagct caaaatggat tatttggttt tacgactttc tttatcatct
    26101 ttaatttagt tttacttgct ttagcatgct gggcaggata caagtggaag aggggatatt
    26161 aacaaaagtg gagaaaacga cattagtttc tctccacttt tatgtttcta attaattagt
    26221 aattataact tattacaatc gaagtcacct atccttatct ttcaaaaaat ggtcaatttt
    26281 agccatcatg agcttgtgtt cgtatatttt acagatatca cgagcctgta aataatagtc
    26341 aagaatttca tcgtgcttta aaaaatcttt tccggcattc gcaacgatag ttaaaagagg
    26401 agccagctga tagctggtct ctttttgttt acaaaagtca atggtttcta aggcttcttg
    26461 gacggcttct aattccttcc ctttagagtg taaataatag gcgaaattat gtttaactcg
    26521 aatataacca aataaatact cttggtggtt taaatctttt tcctgataca aactgataag
    26581 aagtgagtta ttttcttcgt attctgcatc acgccctaca gaaaaataaa aattagataa
    26641 agtattgagg agtttaagat acacagatga gctgaccgaa agctttggca aagcgttttc
    26701 tagactggcg atagcttcat ctttggaact atgtaagtag aaaaggataa tcgattgaat
    26761 ccatagaaga taaaattcat cctcagtaga tagatactga gacttttctt tttctaagtt
    26821 taagaggtat tctaaatcct cgtaattacg atcttcaagt aatttttctg ctaatttctt
    26881 aaacggtgtt atattggaag tcatttcaat ctgttcatcg aaaaaataat ctaagggaac
    26941 ttgaagccga tttgcaagtt tatagagtaa atcagcggca ggcatatagt tgccacgttc
    27001 tattttgctt atttggcttt gctcacaaat tccttcggaa agtgtttttt gtgagaatcc
    27061 tttttctttt ctcttggctt ttagtttatc agataatatg gtcatctcta accctcttta
    27121 aataaattta agattaatta tatactttta atctctattt ttcaactttc taatacaaaa
    27181 atagtcataa aaaaataaaa caaaaaaaaa atgaaaaaaa gaattatttt ttattgacaa
    27241 ataatattta aagtagtaca cttacaagtg taaagataag aaaaaggtgg ttaatatgag
    27301 tattttagca aagtttcgta aaatcatttt tatgttgtcc tttttaggat tgtttggaag
    27361 cggtttcttt ttcaaggaac ctgtaaatca atcacaatat acctgggaat cgagaattat
    27421 acaacaagct gtaacaacta atgaagttga tctgggactg gcggattgat ttgttaaact
    27481 ttttgtgaag taacatttat acaatggatc atgccacaga ttgaagggct taaagggagc
    27541 ttgtaagttt gatataccct attaccctct catataacta actagttata caggaactac
    27601 tttattatat ctcttatgtg ggtgtacgaa tgttcggagg agaaaaatga gaaatccagt
    27661 aatacagaca tttaatttat caaaatccta tgatgggaaa attgtcttag ataggataga
    27721 ttttacatta agacagggag aaatctatgg cttactagga agaaatggta ctggaaagac
    27781 aacctttatc aaggctattt taggcttgac agctatggat agtggtgaag tgaatattct
    27841 atctgaaaaa ctgttaggcg aattttctaa ggatttgcta tctcaaatcg gtgtggtatt
    27901 ggacagtgct tctttttatc ctaatttaac gggacctgaa aatctctcta tttttgcaag
    27961 attgagaggg atttcgctaa aacaggtgga gcaagcttta caagtagtag gattagatgg
    28021 ggaaaataaa aaactattca agcagtattc tctgggaatg aagcaaaggt tagcaattgc
    28081 taacgctatt atgcaccagc cgaaaattct gatattagat gaaccaacaa atggtttaga
    28141 tcctattggt atccttgaaa tgcgccgtta tctaaaggaa ctcagtacca atcatggcat
    28201 ttcgatttta atatccagcc acattatttc agaacttgaa aagcttgtag atagagttgg
    28261 gatactgcat gatgcccacc ttatggctga aaagactatg aaggaattaa tagatggtgc
    28321 agataaaagg aaaatccacc taattgtttc ggatgctcct caagctaagg aagtgctttg
    28381 caggataaat ctgcaagaac agattagtat tctttcggat atagaacttg aacttcaggg
    28441 agaatcacct acttttgaca ttgcagtcgt atctaactcc ttaaaagaca acggaatagt
    28501 tctaaaagaa tattcttata aaaacaatga aagtttagag gattacttta agcggataac
    28561 aggaggtgag ggaattgctt gatttagtga agattgaatt tctcaaacaa aggcatcaaa
    28621 aactgaattt tgtcgtatat ggtgttgttt ccctctacct agctctcatc tgttattatg
    28681 taaatgatgc gagaggcttg tttgactcct ttccctttgt ctataaattc tctttgtctt
    28741 atttaaactt tttgattctc cctttgtatt gtgtttccta tacaatacag gcatttggtt
    28801 tagaatatcg ctatcgcatc atgaacaact tgaaactcgc ttcagcaaat ctaatgaaga
    28861 cattctgggc taagattttg tatatagaaa tcaacgctct gtgtatcatg ttattcacct
    28921 atatttcggt ttccttattc gcactactat cccgcttttc ttcgacagtc agtttgtctt
    28981 tattattaag attcttctat ctttgtatga gtagtggtat cttaattccc atgggagtat
    29041 ttcctttagt tgctttggtc atgataaaag tcagaggcaa ggagatagtt gggaatttgg
    29101 tcggtgtcat gtatgtttta gtgtcatttt ttttagcaag gacgagtcca aatatcagtc
    29161 cagtaacaag tgctaacagt ttaatctggg aaggaaacag agaaggagtg gtgcttcaac
    29221 agccagctat cttatcgatt gttgtactag gtttatcttt acttgttttg tctttcttgt
    29281 ccattaaatc ttggttaaga aaggtggatg aataaatgtt gatgctagaa tttactaaac
    29341 taagaaggcg aaagatactg tatatgattc cctttgtagc catcctgctc tttttgttgg
    29401 agtttatgat tggtcatcag atttatcaag ggcattcgta cggtagtgtg aatggctggt
    29461 atgtagaaaa tggtttcttc tttttgaact actattttct cctccctttt gcgagcatga
    29521 ttttagtgga tttgataaga atagaacaag tgtctaaaac gatttcaaat ctcagactga
    29581 ttcctgtcga tttgaaacaa ttactccaag cgaaatttat gcttgctttg ttgattaatc
    29641 tactagtcag tgaattcact tttttggcta tgctggtcct agagttaatg gatggtgatt
    29701 ttgctttctc tagtcttgca atgttatctt ggggagttgt ttatggagca attgcttttg
    29761 cttatacact gtctgctggt attattgtcc tcttcttagg aaaatatcgg aaggaactta
    29821 tccttgccct accacttgcc tttttattgt catttgcagg tttgtttgct ttaacaacgg
    29881 ttgttgggcg gtattatctg gcaaatttac tactaatcat catggagcaa tttacggctt
    29941 taacagtttc tgtatatgcc atttggttgg ttaccttggt ggcatgtctc ctttatttgt
    30001 tggcagataa acgcatgatg aacattattt ttgcttataa atgactgtaa tcataacttt
    30061 cagagttata attacagcgg atttaaatat ttgctactgg tatctctttt gaatttttaa
    30121 tcccaaagat ttgaggtgtc actatattta ataagagaaa tcagtaacta gaaagggatt
    30181 caacaattat gtctgattgg aaaaaaccta tttacgaatc actaagtaca gaaggtaatc
    30241 cagctgggga tatcttgcgt gaacttagcg atagcgagat ggatcaagct atggctggcg
    30301 gaacagccag atcttattgc gcatgttatt caggagagca ttcttgtggt cgtggttgta
    30361 ctatcaccac agagtgtcct ttcttaacat tcatttgttg ttaatagatt aattctattg
    30421 aatctttggg ataggtgaca cctaaaagta ggatgtcacc tgttatttta tatttaggag
    30481 ttgaaaatga atcgaaaatt aaacataaca gattttaaag atgcttctta tttctctgaa
    30541 agaaaaattt ctagtcatga tttaggggat ggtttgaaat caagaaaaag aaaagagtat
    30601 tgggataatt ttattggaga aggttctaat gaattttgga aatatttaca agaaaaaaat
    30661 gatttttcta aacatgattt agatattttt ttggaagaac atacatatga tgtgaaagat
    30721 atagattcat tttcacatat ggacgaattt atagagttct tttttaagag aaatgattat
    30781 acattaccag agttttatat agttgacagt gagggaaaac gaaaacctat tttcagtaat
    30841 tttgtcatac catttttaaa atttgccgcc tataaacttg aagataattt gagtagtcag
    30901 aatttgaaag tcactagaga cgtcttgaat agtttattaa ttgcgttatt ccaacaaatt
    30961 ttgaatattt cttacagaac attgatatta gaattacaag ttctgaaaga acaaaatatg
    31021 ttaaaaggtg aaactggaga aaaaagattt aaatattttt cagaaatata cttatcagac
    31081 catttttggg atatattaaa agaatatcct gttatgtttc gattaattat tgaaaatatt
    31141 caaaattggg ttactaataa tgtagaattt ttaacaaacc taaaagaaga taaagcatta
    31201 ttacaggaac atttttctat caatggggag ttaacaaaga ttgaatctgg tgtgtcagat
    31261 tttcataatc atggaaaatc agtatatctc ctttggtttg gaacaaataa gttagtatat
    31321 aaaccaagag atttaatatt ggatgtgaag tttcaaaact tgcttagctg gtacaacctg
    31381 aaattcaata aaaatctata tgtaacaaat attttgaatc gtggaaatta tggatgggta
    31441 gagtacatag aacacttacc atgcacatat gaatctgatt ttattcagtt ttatacacat
    31501 ctaggatact tgttattctt attatttgct atgaggggaa acgatattca ttttgaaaat
    31561 atcatagcta agggtaatag accagttctt gtcgatattg aaacattatt tcataataca
    31621 acggaataca gaaaggaata cgaaacggca gataaactaa tattctcttt attagaaaaa
    31681 tctgtgaaaa gagtaggtat tttacctaat atagtttggg gtaaagatgg gaactctggg
    31741 gtggatatta gcggtctaag ttcaagcgca ggagagatga ttccgattga acgtgcaagt
    31801 atcatgcata gtatgacgga tgaaatgaaa attggttatg aacaatccgc attgcaaagt
    31861 aaagataatc agccttttat tcaatcgggc aaggatgttg atttgaattc atataaaaat
    31921 tacgtttctg ctggctttaa agaagcttat gaaattattt caaaagatcc ttcatcaata
    31981 gaagagtttc tggttgagat agaaaaattt aataatgcgt attctagaca aataatgagg
    32041 cccacacaat tttattctaa tttaatacaa acatcttatc atcctagttt tttaaggagt
    32101 ggtctagata gggaaatgtt attttcaaaa gtttggaaaa tagtttttga ggataaaaaa
    32161 gtacaaagaa tagctagttc agaattcgaa tcattattat tgggtgatat tccattattt
    32221 cagacaaaaa tatctgatag attcttatgt tctgaactaa cgaaatatca aaatttcttt
    32281 aatatttcag gaatggaatt agcaattcaa caaataaaag acttttgtca gaaggatatg
    32341 gaatttcaat taaatttgat tgaaacaact ttgaattacg atccttctta taatttagtt
    32401 caggattctt ttgtacctct aaaaccatct gtaaaagtga tacgtaattt aaatcagaaa
    32461 gaaatacaag aaactaaaag tagaattgta cctctaacag aaaaaattgc tgactattta
    32521 tctaaaattt catatagtgg tacttcagga gatatatgct gggtagacat gaacatactg
    32581 ggagagaaaa cgaatgattg gaatatggtt ccaatcggat gcgatctgta taatggtata
    32641 tcaggtatta tgttattcta tttattctta tatttggaga ccaagaaaaa agattatctc
    32701 atatacttga aaaaatgtta ccgatctctc aagtattatt tagattcaag aaagcaattt
    32761 gctactcact ctcaggtact gtttggaggt ttttctggag agacccctat tatatatgta
    32821 ttattgttac tgaagacaag gatgcctgaa cactttaatt ctgatgaact agatgtttat
    32881 atctatgata ttattgatga tttaaaaaaa gggtatagat atgatgaaaa ttttgatgtt
    32941 cttgtaggtt ctgctggtgc gattatacat ttgctaaatg tatttgaagt tactagagac
    33001 gaagaactct tgatattagc gcatgattta tttagtcatt tagaaaaaaa ttctacaaaa
    33061 attactgttg aagggcaaga tggaagagca tggaaaggaa cgatggcttc caatccttta
    33121 gcgggttttg cacacggagt ctcaggaatt gtgtgggcac tgtcaaaact tagtagatat
    33181 ttcccagaag ataaaaagct taaaactatt attaaacaag gtataatttt tgaaaattct
    33241 atgtttgata ctgaaaaatc taattggtcg gattatagag aaaccgaaag tggtatcaaa
    33301 tataaggata ttgttgaaaa tatccctgtt tcgtggtgcc atggtgctcc aggtatactt
    33361 ataagtagat tagaactgta taaaaataat acattgaatg tagagtttcg aagaacaatg
    33421 aaatctgata tggatgtagc aattgataca acaataaaat atggttttgg aaaaagccac
    33481 tgtctatgtc atggagactt aggaaatcta aacattctat tttatgttgc taagaaaatg
    33541 tcctctgagc atttatacaa tgtagtttac tcctatctta atacgattct tgatgattta
    33601 gaatcagaaa attggaaatg cggtcttccg tataagaatt ctccaagtct aatgagtggg
    33661 atagctggaa taggattagg cttactaact ttgaataatt tatcaattcc ttctgtaatt
    33721 aatctagaaa tttggtgatt caaattgaaa aaggtaaaat tcatacaaca attatctgag
    33781 accagttgtg gtttagcatg catggcaatg attttagatt attatgggca tgaggcaaac
    33841 ttatatgaat tatgctgtga ttttgagaat tcaagggatg gattatccat tagagagatt
    33901 aaagatatag cttcttattt tggattggat tcaaaggcga ctgagatctt aaatattaaa
    33961 aaatttttgg ggaacaaatt tgtagaacct tatatagctt taactcaaaa tgctcattat
    34021 attgtggtgg aaaaacataa tgagcatagt gtagtattca ttgatccaga acgaggtaga
    34081 attacagaag atatatcaaa ctttgcgaat aatatatctg gtattgtaat tttcttctca
    34141 ccaaatagga aattcactaa aaaaaagaag catagtaatt tttttaaaat attgaagata
    34201 ggtaaaattg atattaaaag gctatgttat atttctttaa tatcaatttt ggtacagagt
    34261 ctcaccttat tattaccttt gctaacaagg tttattattg ataatgtaat tagcaaagga
    34321 gaaatgtatc gtttagggat gcttttttca atcttttctt taataacatt ttatgcatta
    34381 tttagcttta tacgaactaa attaattatt acagttgaaa agagatacat atttacatta
    34441 aaagataaaa ttgttggcaa aattttcact ctacctatga aattttttga tagtagatct
    34501 tcaggtgaaa ttgtaactcg aatcaataat ttagattctt tagagaaaat aatttcaagt
    34561 ggaatatcaa gtttgttaat tgatctatct acaattatta tcgcttttat agctatggca
    34621 atgatttcat tatatttcac acttataatc acatgttttg ctatattttt gtttattgtt
    34681 ttatattttt tgttaaaaaa attggaagaa aagaactcaa actttatcag ttctaaagaa
    34741 ttgactcaag gttatttgat ggaaattttt tctaatttat tatttttgaa agtctcagca
    34801 aaaggagatg tttcatatac taagtggaaa gaaatgttta gtaatgagct taaatttgat
    34861 gtagagcgtg aaaattatct aaatattttt cagactttta tttctattta tagactcgta
    34921 ccaaacttac taattttaat tttgggagga ctagaagtac agcagcatat gatgtctctg
    34981 gggagtttaa tgtcattttt atcattggta tctttgcttc tttcacctat tactctaatc
    35041 gtacaaaact gttttcaatt tcaattttgt tttacaattt tagatagagt gtttgatatc
    35101 atttatactc cagaagaaaa aaatcaattt tctatttcta aactaccccc atttgaaatg
    35161 atgactttca gaaatttgag ttttgcttat agtagtgcct gtaaagttat ttatgatata
    35221 tcattaacta ttaagaaagg tgaacgtatt gctatagtgg ggaggacagg ttgcggaaaa
    35281 actacactta ttaaattatt gctacggctg tatgatgtag agaaaaatac gattttatat
    35341 aatggtaatg atattaattt atttgattta aatagttata ggaagagttt cggagttgtt
    35401 ttacaaaatg atgtaatgtt taacgacact gtgatttcca atatagattt aactcatagc
    35461 cattctatgg aggatgtcat ttctgcagca agtttagctg aattagatat agagattaat
    35521 aatatgccta tgggatacta tactagtatt ggggataatg gtaacaattt atcaggtggg
    35581 caaaggcaac gcttagcaat agctcgagcc attttgcaaa atccagagat tataattttt
    35641 gatgaaggta ctggtcaatt ggacactata acagagaaga aaataatgga taatttaaaa
    35701 cataaaggaa ttacccaaat ttttataact catagactat ctaacgctca ggaatacgat
    35761 aatattattg ttatggataa cggtaaaatc atagatagcg gaaaacatga tgagttatgt
    35821 ggtaaagaag gtatgtataa aaggcttttt gaaacctcat ataattaatt gtgattaggt
    35881 tttatgagtc tgtacaaaaa gtctcgaaaa gcagaacacg cataatatca agaatcacaa
    35941 aaaccttgat actatgcgtt ttattgtcgg aggattttct taattttctc ttgtaattga
    36001 gttttagtga ctatactttt tcttgtgata aaacttacaa gttctttttg ttattcttga
    36061 cctagttttt atagaaagaa ggtctaagat gttaaataaa gtcaaaacta aagccttaat
    36121 tagtgttgga gcagtagccg caactagctt tattctcatg gtgggatata ctattggtca
    36181 acattctact gctaaacaaa gtcgcaaaga aatcgaattg gctgcaacta aacttgtaga
    36241 ggacaaacaa gctgaagata aagccagcat tttgtcatcg gatactgtaa aagaattttt
    36301 gacgcagtac tatacgaaag aaaaactagg ggaaaataat acacgtattc aaccttatat
    36361 gactgaatcg gcttattctc aagaattgtc aagtcaaaat gatgccatga accaagtgta
    36421 taaggattat attttggatt atcattttga aaaagctgat atctttgtca atcagactac
    36481 gaatcaagct attgccatgg tctcttataa tgtaacctat gtatctgatt taaagaatgc
    36541 caaccaatca aagactaatc agacagaaac cagaacggtt aagttgtctt attcgaaact
    36601 accaggtaag ttattggtca atcaagtaca ggtttggaaa tctgggttag atgatttaga
    36661 taaggtaact cctaaaactt tagaagaatc atcatcaata ccatcactgc caaatactac
    36721 gacaaaatga tgatgttgca tggaaataga agaatgtaag aaaatttcaa ttcttgatgt
    36781 agccaatcgt ttggggatct cctttaaaca agtttcgagc agtgtctatg aacatcctga
    36841 acacgattca tttcggattt tttcaactac caatactttt aaatggtttt caagagatat
    36901 tcaaggtgat gtcattgatt ttgttcgact tgttaaggga atttccttta aagaagctct
    36961 agcctttctt tctgaagaac cttttcaaaa agaagctgtt caagaaaaaa gagagagacc
    37021 attttattac cctttaaaga gaatagaaga ttctaactgt agtctggcca gatattattt
    37081 aacagaatgt agaggaattt cagaagaaat catacaaaag atgattcaac aaggtttgat
    37141 gtcacaagcc agttggaaaa caaatgaaac tgttgaacct gttattgttt ttaaaagctt
    37201 tgatcatcga cacaaactgc aggcagcaag cttacaaggg atttataaga atcactctct
    37261 tcctagagag aggttaaaaa cgattctaaa aggaagccac ggacatgttg gaatatcctt
    37321 tgacattggt aaaccaaata gactggtctt ttgtgaatcg tttatcgact tgatgagcta
    37381 ttacgaactt catcaacaaa atctatttga tgttcgtttg gtatctatgg agggattaaa
    37441 aaggtctgtt gttgcttatc aaactttacg actgatagct gaagaaaatc agaagttgga
    37501 atttttagat acagtaatac cttcaaagtt attgcctttg atcaatacaa ttcgtgatac
    37561 caccagctat tttgataatc atcctgattt attgacactg gcagtagatt gtgatgatgc
    37621 aggtaaagat ttttctgata agttatctag atcaggattt cctgtttttc tggatttacc
    37681 tgataatgaa tctgggaaag aaaaacgaga ctggaacgat attcttcgag aaaagaaatc
    37741 agatttacaa ttgatgatcg agaatgcaaa agagacattg aggaatcaac cagtaagaca
    37801 aacatctcaa tgtttagaat tgtgataaca aaatcaagat gttttagcta atattagaat
    37861 gaaggaggat cgtatatgac cattattgaa cgcttagaag aaaaggtcac taggcaagaa
    37921 agcaaggtag caagagagac agaaaaacta gctgcttaca aagagcaact ggagacagcg
    37981 atgtttgcga cgttcaaaag gcgtcaaagc attagtcaca tgagttttga agaagctctt
    38041 gaccatgcat ttggcaaaga aagacaattc gatgattctg aatttagaaa ggatgaaatg
    38101 agtgaatgac aaaagattgg aattttaatc aaccattaga aagcaaatca gaaaatcaag
    38161 aagatccaga taaaattgcg gccttatttg gaaatcatca aggaggtaat gaggtaaatt
    38221 atgaagcagc ttttcaaaag cgtaaacaag cacctgtgac ggaatcaaat tctagttcta
    38281 aacctaaagt tacagaggtt agaacaggaa aagagacaga tatcactaca agttatcagc
    38341 aacatcttaa aagacttatt gcagataaca atagcgatat tcaaagtagt caaaagaaaa
    38401 ttgaagagct acatactttg attgacacaa agaataaaga caataagaaa ttgcagtcca
    38461 tttatgatgc gatttcggaa ttacactaag cagtcttaaa aggctgcttt ttttgagagg
    38521 ttatagatgt ttacaaaact ttttaagaaa aaccaagaca atagtgatgt atttaagaag
    38581 ctaattcata gactatctga tatgtctatc caagatctta aaaaaataga tcgactgtta
    38641 gatatcattt tcactccaga tcaaggatca gaacaactaa aaacagaagc aacttataga
    38701 gaagaaactt tggacgacac attaaaggaa gccaagaatc aacttcatat ggaacaattg
    38761 gagaagaatt tagagaggtt taggaaaaat agtcaataac acaccaaaat tggtgcattt
    38821 aatttttcta aatgttataa tggtggtatc aaatgaaagg agtttgccat gattggaaag
    38881 aacataaaat ccttgcgtaa aacacatgac ttaacacaac tcgaatttgc acggattgta
    38941 ggtatttcac gaaatagtct gagtcgttat gaaaatggaa cgagttcagt ctctaccgaa
    39001 ttaatagaca tcatttgtca gaagtttaat gtatcttatg tcgatattgt aggagaagat
    39061 aaaatgctca atcctgttga agattatgaa ttgactttaa aaattgaaat tgtgaaagaa
    39121 agaggtgcta atctattatc tcgactctat cgttatcaag atagtcaggg aattagcatt
    39181 gatgatgaat ctaatccttg gattttaatg agtgatgatc tatctgactt gattcatacg
    39241 aatatctatt tagtagaaac ttttgatgaa atagagagat atagtggcta tttggatgga
    39301 attgaacgta tgttagagat atttgaaaaa cggatggcag cctaatggga atccaagatt
    39361 ataccgatag tcaatttaaa caggctttag caaggaacat tcgctcactg acaagaggaa
    39421 aaaagtccag taagcaacct atagcgattt tgctcggagg gcaaagtggt gccggtaaga
    39481 ctacaattca tcgtattaaa cagaaagaat ttcaaggaaa tattgttatc atagatggag
    39541 atagttttcg ttctcagcat ccacactatt tagaacttca gcaagaatat ggcaaagaca
    39601 gtgttgaata caccaaatat tttgcaggta aaatggtaga gtctttagta agagaattga
    39661 gtcatttggg atacaatctt ttgatagagg gaactttacg aactattgat gttccaaaga
    39721 aaacagcaca actcttgaaa agtaggggat atgaaataca attagccttg attgcgacaa
    39781 agcctaagct gtcctatctg agcaccctta tccgatacga agaactgtac gctattaacc
    39841 caaatcaagc acgcgcaact ccaaaagaac atcatgattt cattgtaaat catctagttg
    39901 ataatacacg acaattggaa gaactagcta tctttgaaag aattcaaatt taccaacgag
    39961 atagaggttg tgtatatgat gcaaaagaaa atacaacttc agcggcagat gttcttcaag
    40021 agttactgtt tggggagtgg agtcaagtag agaaggatat gcttaaatct ggagaagaaa
    40081 gattgaaaga tttaactaat tgaaatggtt gttagatctt gagttttaaa ataaagccta
    40141 ttaaaaattg ctatctctta gattatggta aaaaaatggc ttttaattaa actaacaaag
    40201 tgagtataaa taaaagtaat aaatctcacc gtcattcttt tttaaattaa tcgttgttct
    40261 caaaatattt ccaatttatc ggactttttg tactagtctt atacttttta gttaattcta
    40321 tctggcctat agtattgaaa ataatttgta gacttggcaa tgagaattcg ttacagttta
    40381 gtagagccga cgtattccga acatcattta cggcggtgtg aaaggtgata taaataatat
    40441 tatatctatt gatattcaaa atcgtttcct cactcagatt cttttataat cgagaatata
    40501 ttaataaaat ctatttttgt atttaatatt aaaacatcgt aaaatatagt aattctacaa
    40561 aaagaaagga aaaataaaat gactacaact aaaaatccct ggaatcaatt atctaacgtc
    40621 gatataaatg gagagcaagc tattcttgct accgaagatg ttgaactaat caaaaaatac
    40681 acctctacaa aacactacaa aaatctaaaa gatgatatct accgtttaca attaggtttt
    40741 tgtccgcaac aatttgtggg ggatattcaa aatgctgata tcattgtttt atctaaaaat
    40801 cctggctaca cccctgaatt taaaacactt tatgaccacg ataaaaacta ccaaaagact
    40861 cttttaaata atctacagct aaaaggaaac ctctattttc atgcttttga cctagatacg
    40921 aatgaatttg gttactgggc taaaaagttt aaagtatggt ttgatgatgt agacaattta
    40981 caggatttaa aagaaaagct tccttggttt tcaaaacacg ttgctttagc tgaatatttt
    41041 ccatattact ctactaagta cgatgataaa ttaaatgatt ttataagcaa agaaggttat
    41101 ttcccaacac aaaagttttt attcaattta attagagaac gtgttttgga tgacaatgat
    41161 cctgtaatca ttatcatcac acgatcttac aataagtggt acgatgcaat tcctcaatta
    41221 aaagagtata aaaattgtta tgaaacgagt aatcctagta atccttcttt aaaacctgag
    41281 aatttattaa aagtcaaacg atattctgct aaaaaagagg ttgaaaaagt attagaagat
    41341 tcattgaaaa agctagagca taaataaaac agtctctttt taatgctatc gtaaatactg
    41401 tattgtgtag ttattagtaa acctatatat tgtccccaaa tttatttaga ttattctcta
    41461 ggattttact tgattttaaa gaaaatatag tttaacatat aaatagttca gaatcagaat
    41521 gaaggtagaa taagaggatt attttaatta atttttaata gtatggagca gaacttttat
    41581 aatatattta aataggagta aaaaaatgaa ttatcaaaaa ttaaatgata ttactggtgc
    41641 taccaaaaat gaaaaagata aatactatgt ttacggactc tatgaagaag gtaagcaact
    41701 acctttctat attggtaaag gagagggaac tcgcctaata tcacatatcg atgaagcgct
    41761 tacagagata aatcaagaag aaaacataca aattagtaaa aaaattcaaa ttattagaaa
    41821 acataagggc aaaattatac ctgtaatcat ttaaagcacc cattagttca acaaacgaaa
    41881 attggataaa gtgggatatt tttaaaatat atatatttat gttacagtaa tattgacttt
    41941 taaaaaagga ttgattctaa tgaagaaagc agacaagtaa gcctcctaaa ttcactttag
    42001 ataaaaattt aggaggcata tcaaatgaac tttaataaaa ttgatttaga caattggaag
    42061 agaaaagaga tatttaatca ttatttgaac caacaaacga cttttagtat aaccacagaa
    42121 attgatatta gtgttttata ccgaaacata aaacaagaag gatataaatt ttaccctgca
    42181 tttattttct tagtgacaag ggtgataaac tcaaatacag cttttagaac tggttacaat
    42241 agcgacggag agttaggtta ttgggataag ttagagccac tttatacaat ttttgatggt
    42301 gtatctaaaa cattctctgg tatttggact cctgtaaaga atgacttcaa agagttttat
    42361 gatttatacc tttctgatgt agagaaatat aatggttcgg ggaaattgtt tcccaaaaca
    42421 cctatacctg aaaatgcttt ttctctttct attattccat ggacttcatt tactgggttt
    42481 aacttaaata tcaataataa tagtaattac cttctaccca ttattacagc aggaaaattc
    42541 attaataaag gtaattcaat atatttaccg ctatctttac aggtacatca ttctgtttgt
    42601 gatggttatc atgcaggatt gtttatgaac tctattcagg aattgtcaga taggcctaat
    42661 gactggcttt tataatatga gataatgccg actgtacttt ttacagtcgg ttttctaatg
    42721 tcactaacct gccccgttag ttgaagaagg tttttatatt acagctccag atccatatcc
    42781 ttctttttct gaaccgactt ctcctttttc gcttctttat tccaattgct ttattgacgt
    42841 tgagcctcgg aacccttaac aatcccaaaa cttgtcgaat ggtcggctta atagctcacg
    42901 ctatgccgac attcgtctgc aagtttagtt aagggttctt ctcaacgcac aataaatttt
    42961 ctcggcataa atgcgtggtc taatttttat ttttaataac cttgatagca aaaaatgcca
    43021 ttccaataca aaaccacata cctataatcg ataaccacat aacagtcata aaaccactcc
    43081 tttttaacaa actttatcac aagaaatatt taaattttaa atgcctttat tttgaatttt
    43141 aaggggcatt ttaaagattt aggggtaaat catatagttt tatgcctaaa aacctacaga
    43201 agcttttaaa aagcaaatat gagccaaata aatatattct aattctacaa acaaaaattt
    43261 gagcaaattc agtgtcgatt ttttaagaca ctgcccagtt acatgcaaat taaaattttc
    43321 atgatttttt atagttccta acagggttaa aatttgtata acgaaagtat aatgtttata
    43381 taacgttagt ataataaagc attttaacat tatacttttg ataatcgttt atcgtcgtca
    43441 tcacaataac ttttaaaata ctcgtgcata attcaacagc tgacctccca ataactacat
    43501 ggtgttatcg ggaggtcagc tgttagcact tatattttgt tattgttctt cctcgatttc
    43561 gtctatcatt ttgtgattaa tttctctttt ttcttgttct gttaagtcat aaagttcact
    43621 agctaaatac tctttttgtt tccaaatata aaaaatttga tagatatatt cggttggatc
    43681 aatttctttt aagtaatcta aatccccatt ttttaatttc tttttagcct ctttaaataa
    43741 tcctgaataa actaatacct gtttaccttt aagtgattta taaaatgcat caaagacttt
    43801 ttgatttatt aaataatcac tatctttacc agaatactta gccatttcat ataattcttt
    43861 attattattt tgtcttattt tttgaacttg aacttgtgtt atttctgaaa tgcccgttac
    43921 atcacgccat aaatctaacc attcttgttg gctaatataa tatcttttat ctgtgaaata
    43981 cgatttattt actgcaatta acacatgaaa atgaggatta taatcatctc tttttttatt
    44041 atatgtaatc tctaacttac gaacatatcc ctttataaca ctacctactt tttttctctt
    44101 tataagtttt ctaaaagaat tattataacg ttttatttca ttttctaatt catcactcat
    44161 tacattaggt gtagtcaaag ttaaaaagat aaactccttt ttctcttgct gcttaatata
    44221 ttgcatcatc aaagataaac ccaatgcatc ttttctagct tttctccaag cacagacagg
    44281 acaaaatcga tttttacaag aattagcttt atataatttc tgtttttcta aagttttatc
    44341 agctacaaaa gacagaaatg tattgcaatc ttcaactaaa tccatttgat tctctccaat
    44401 atgacgttta ataaatttct gaaatacttg atttctttgt tttttctcag tatacttttc
    44461 catgttataa cacataaaaa caacttagtt ttcacaaact atgacaataa aaaaagttgc
    44521 tttttcccct ttctatgtat gttttttact agtcatttaa aacgatacat taataggtac
    44581 gaaaaagcaa ctttttttgc gcttaaaacc agtcatacca ataacttaag ggtaactagc
    44641 ctcgccggca atagttaccc ctattatcaa gataagaaag aaaaggattt ttcgctacgc
    44701 tcaaatcctt taaaaaaaca caaaagacca cattttttaa tgtggtcttt tattcttcaa
    44761 caaatttggt ttaacagagc acgaagcttt tatggctgaa tcggcattaa ttaatcttat
    44821 caatttttca aaagagaatg aagaattaac aaatttagtt agtggacatg cgtcaaaaag
    44881 agaaaaagca acaatctcca aagatggact gattcaggct agatcaattg agaactttat
    44941 tgataactat gccttatctg attttgattt ttcaacgatt aaagaaaaat gtgtattcat
    45001 taaaatcaat aatagctttc aagctgatga cactacagaa gatatttatc acaatgtacg
    45061 tggtgtttgg aatatttctg aatcacgtaa aaaagactta gagtatgctc ttgccttata
    45121 ccgtggtgtt tgtgttggtg tttataaaat tcaaggttgg aagaaagctt acgaacattc
    45181 ctcagagtat cctttcccaa caaggaaaga agggggtaaa atagaaacta gtgaagaaac
    45241 tattgtgaaa tattctaata tagaggattt aaaaaaagat tatccagaat tatataaacg
    45301 cagtttctct aattcagaat ttccccagaa atctttagat aaatggagaa atagaagttt
    45361 cttttatggc aactgggatg gatcagatgt acctcaacac cttgctcaat gtctaaataa
    45421 gcgaattatt aacatcccta aattcactaa atctgttaaa gaatttaaat ctattgataa
    45481 tcaagcatct gttatctata atgatcttaa atagctttaa atctagatct cgtaataact
    45541 tttttaatta attgtagtaa gtttaaagca atctatcttc ttaaaatatg attccattgt
    45601 ataaacgtca aaatattatt ttgttaacca tttcattttt aaacttctgt atagtttttt
    45661 attagaattt aattaaagtc aatattttta tgtcaagaca cgtagtatca atgcttttta
    45721 atgccttgta ttatgtgttt ttgatttgtt aaaaatttta taccatagac aaaatatgtc
    45781 taccttatga tgtataatac ttatatagac ataagagaaa gaaggtaaat gatatatggc
    45841 aaattcatca gaagcacatg gcagagttta cattaaagca tcaaatctta aaactattga
    45901 ggattttctg ttaattcaag aagaaagaaa taagtatgtt tattatccaa ctgatattat
    45961 agatagccaa tctaacatat cagatatagt ctcctcaaga acaactcaag aaaatggtta
    46021 ttatatatgc aacatgtggt ttactgctga gggtagatgg tgttttgaga ataatataga
    46081 tgactttttt gattgtactt tatttcaaga tacagatgat gttcttataa gacaaatgaa
    46141 ggaatatgtt tgtagtcaag atattcaaat caaatttgag tatgtagatg ctgaagctag
    46201 tcagaatttt gttaaggaac aagaagcaac aattacatat aattcaaaaa caaaagatat
    46261 aagtatagat gttaaaacca taaaggacct accttacaca gcagaaaacc taatagttta
    46321 tggatactat gaatgtgatg aaattgtttc cgttcaattt ttgcttgatt actatgatga
    46381 ttatttaaga ggaaatgaat tttatttaaa acataaagat ggaattgtcc ctattttaga
    46441 aaggcaacaa taaaaagaag aaatcttctt tttattagaa tcacttgaat catcaattcc
    46501 tgagttaaaa gaatatgtag aaaagaataa ggagtaataa attgaaagct attgtaaaaa
    46561 atccaaaaag actatttgaa cttttgagat tatattttgt tccagtaaaa ggtaggaaag
    46621 tagttcatgt accagcttat gcttataaag aagatgaaaa tgaaaagatt tatctccata
    46681 acaatgaact tcatttatct aaaaagatgt ttgaatttct agtaaatcaa ggtttagatt
    46741 tagtagaatg tcttccagaa gagtagtgta tgttgttgat taactttact aaatttttaa
    46801 atttaaaagt acaataaaaa atatatattc aacagagaca aaaggaggaa atagttttat
    46861 gacaaatgcc aaagaattcg cattaactgc tcacaaaaat caaacaagaa aagggaaaat
    46921 cacaccttat tcatttcact tatttttggt caataatata ttagaaaccc taacagaaga
    46981 tcctcatatt atagctaccg gatggttaca tgatactgtt gaagataccg atgtcagtct
    47041 tgaagatatt aaacaagaat ttaatgatga aatttattca tatatgtctt tggaatctga
    47101 agataaatca attaaagatt ggcaaactcg taaagagctt caattggcaa aatttcgaga
    47161 agcagcagaa gatgagtcgc taagaaaagt tttacttgta actttttctg ataaattagc
    47221 aaatttaatg gaactgtatc aagattactt aataattggt ggtttactat gggaccgttt
    47281 taattcaaag gatccgaaaa aacaacgatg gtactttaac gagttttata aaatctttaa
    47341 agataaccaa gatttatttt cgaaaaacaa agatatttta aataactata aagaaatttt
    47401 aaagctttta ttttataaca attaaaaata tgtttttaaa attatctttt aattaaatgt
    47461 aaatagaaag gatacaaatg aataaaccaa tagcagctat atttgatatc gacggaacaa
    47521 tttttagaga ttccttactt ttaaagcata tggaaaagtg tgtttcctat gatgtatttc
    47581 caaatagtgt caattctgaa attaaatttc acaaaaatgc ttgggaaaat agagaactag
    47641 actatgatga ctatctctat attgctgcaa cactttatac aaaatatatt gcggataaag
    47701 acatacttga tattgatttt gttgccaaaa aagttattga aaaagaaagt aaaaaacttt
    47761 atcgatacac tcgtgatcga atcaaatggc ataaggaaca ggggcaccaa attatattta
    47821 tttcggggtc tcctgatttc ttagtctcaa aaatggccga aaaattgggc gcagatatct
    47881 ggtatgcaag caattatctt caacttgata gtaagtatac tggagaagtg attcctatgt
    47941 gggattcaac ttcaaaatta caagttttaa aaaaattgtt tattgatttc gaaaaatcct
    48001 acgcttatgg agatacaact ggtgatttta caatgcttca atctgtagga tttccgacag
    48061 caataaatcc caataagaaa ttattggaca aaattacaat ggagaaacta gattgtaaaa
    48121 tcattattga gagaaaagat gtgatttata aactagatga ggtcacgcat ggaatttatt
    48181 agagctgcga atcaatttat agaaaattac tatccaagag aagatcttga ccgtattgaa
    48241 agtatagaga taggaataag ggattctgaa aattattctc gatatttttt agaaattcaa
    48301 aaacaatctg aagagtttga gtgtgacttc tttaattttg ataacataga ttattatgta
    48361 gtggatgatt ctgttcattt taaacagatt attaacttag agaatagttc ctatgtgttt
    48421 tggaaagatt attaatttta acaactaaga cattagattt cagctcttag aaaataaagt
    48481 ttaaaaattt gtgctggtaa gaaattaaat gagtataccg ataggtatta agtaggttat
    48541 aaattgctca tggttaatat ttatgataaa attaagtaca gatatgaaaa cacttacaat
    48601 atgttgcaca aattgaaaat gtaatcgtag tttataacgt agaatttaat ttagcttgta
    48661 agacttcatt caaaaataca tctgagatag gtgttacatt ttttatgtga gggggaagta
    48721 cagtttttta ataaatatgt tatcaaaaaa taatcgaatc ttgctaaaaa caaaaaagat
    48781 tcaatatata tgtttaatca ctctattacg gagtgatttg tcttattttt atatttatga
    48841 aaggattgct tatgagtggc tcattttctg atagtcctac ccatgatgac aaatttagca
    48901 ttgagaacta tattaatggt ttatcaaatt ttattattga gtgtgaaaca cccttaacgg
    48961 ttgccattca aggagactgg ggtactggaa aaaccagtat tatgtaccaa gttgaaaaaa
    49021 gattaaatcc tgaaaaacaa gataaaaaaa ttcaaactat ttttttcaac acttggcaat
    49081 actcacagtt tgatatggga aataatttag cagtagcatt aattacagat ttaattagtg
    49141 agttgaatgt agaagattca aaaaagaaac agttttttaa aaaagcaaaa ggtgcgctat
    49201 ctaaaggctt agaatatgta aatttagact ttggcatact aaatggagaa aaattaactg
    49261 aaaaatttca agatttaatc ataggttttg gcgagagaac tgatgatatt aagcatttaa
    49321 aagaaaactt acaagacatt attaatgatg ccattaagga aaataaaagt gatcgaatag
    49381 ttatttttat tgacgatctg gatcgattag ttcctgaaaa ggccatagaa ctcttagagg
    49441 ttttaaaatt atttttagac tgtgaacatt gcgtctttgt attggctata gattataatg
    49501 ttgttgttag aggtgcaaaa agtaaatatg gtaaagattt agatgatgaa aaggggaaag
    49561 ctttctttga aaaaattatt caagttccat ttacagtacc agtagcaaat tatgatttgc
    49621 agaattttat tgaatcctca cttaaaaaac ttgatttttg ttttgataaa aataataaag
    49681 aaagaaatca gttagaaaca attactcaat taattagata ttctatagga aataatcctc
    49741 gtagcattaa tagacttttt aattcagtca gcctcttaat gtatatcaat aatggagaca
    49801 aagtagatca tgatgaaaaa ttgatgatat tagcaatggt atgtttccaa ttaagattcg
    49861 aggaagcata caactattta ttgacagcat ataataatag tcccgaagat agcgatgata
    49921 tagaatctta cttgatagat ttattagaaa attcttttga attattagat gatgaagttt
    49981 attataattc attagtatcg cttcttggaa aatttacatt taaagataag aaggatagag
    50041 atgattttac caatttctat agaactttga aggaattact tggatataat gaacaaggat
    50101 taaccatgga acaatttaac aaactaattg aaaaaatgac attctcaaat gctgtttcaa
    50161 ttggaaatac agatacaatt acagcagata agaaaaaaca gaatcatgct ccaaacgaag
    50221 atgtgcagtt tgtaattcgt aaactattta atactttagt tggtgatgaa aattactttg
    50281 atcttaaaaa gccagagtta ttcggtaaag aaacacgaga aaaacgagaa gctcctttat
    50341 ctgaggaatt tatttcgatt ccaaatgaat ttgatagaat cagattaaca agaggaaaag
    50401 gacaaggttt aaatatatac tcttcacata ataaatcaaa ttttatttat atttcagggg
    50461 atacgcacgg tcgaatgctt aatgatggaa tggcaattgt tgttaataac aatttggtag
    50521 aaaagataaa agataatatt ttagctagtg acttgcgaag tgaagaactt tatcacgaat
    50581 ttgagatgaa ttttagagat aacttaaata aactattatc taaggcaagt aaaatattaa
    50641 ataattaaat aaatttaaaa ataactaaat tataaaactg taacttagta atcatgccca
    50701 aatagatact gatgaaaaga tgatttctgt tttaaattat cttttcctaa aaaattaaat
    50761 aacacgctat atgatttagt tttgtaattg atacagatta ataaaatctt gacgaaattt
    50821 tatatataga cattaattgt ctatggagtg ttgtaaaatg atattgttaa tgaaattaac
    50881 ataaaaataa taaaattgag gatagattta tgtcagtaca gaaaacaaaa aatacattaa
    50941 atgaaccttt aaaaacattg cttgatgaat atcatgataa agtgggaaaa attaacaact
    51001 cttcagaact attcgatata tatagcccgt ggaataattt taatatagaa aaaatgatag
//
LOCUS       DAVHTH010000009        48136 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.009, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000009 DAVHTH010000000
VERSION     DAVHTH010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 48136)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48136)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48136
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.009"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            9..89
                     /locus_tag="VVR63_000526"
     tRNA            9..89
                     /locus_tag="VVR63_000526"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:43..45,aa:Tyr,seq:gta)
     gene            94..164
                     /locus_tag="VVR63_000527"
     tRNA            94..164
                     /locus_tag="VVR63_000527"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:126..128,aa:Trp,seq:cca)
     gene            179..251
                     /locus_tag="VVR63_000528"
     tRNA            179..251
                     /locus_tag="VVR63_000528"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:212..214,aa:His,seq:gtg)
     gene            265..336
                     /locus_tag="VVR63_000529"
     tRNA            265..336
                     /locus_tag="VVR63_000529"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:297..299,aa:Gln,seq:ttg)
     gene            346..429
                     /locus_tag="VVR63_000530"
     tRNA            346..429
                     /locus_tag="VVR63_000530"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:380..382,aa:Leu,seq:caa)
     gene            536..1813
                     /locus_tag="VVR63_000531"
     CDS             536..1813
                     /locus_tag="VVR63_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylcysteine synthetase"
                     /protein_id="HEU6128577.1"
                     /translation="MSCSIDLLKHRYLKNIKENPELFVGIELEYPVASLEGDATDVEV
                     MKDLFHYLVSTLDLTVAKVDDFGNLIQLVDPISQDAILFEVSYTTIEFAFGKAETIQE
                     VENRFNNYMNVIQRKLAESNHAIVGCGIHPNWDKNENCPVAYPRYQMLMDYLNLSRNI
                     IKSDLHHFPEYGTFICGSQVQLDISKTNYLRVINAFTQIEAAKAYLFANSEFSGADWD
                     TKISRDIFWEESMHGIYPENVGVNARLLNDEADFFDYLNHSAIFTAERDGQTYYFYPI
                     QAGDYLATSEIQAFALNGDEVIIYPQEKDFETHRSYQYQDLTTRGTVEFRSVCTQPLD
                     RTFASAAFHLGLLVNLDKLEAYLETAPFFKVFGYDYKSLRRQFSKKNLTDEEETTIIE
                     FSKDLLLLAEEGLVVRNKEEMTYLQPLREELSL"
     gene            1889..3373
                     /locus_tag="VVR63_000532"
     CDS             1889..3373
                     /locus_tag="VVR63_000532"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HEU6128578.1"
                     /translation="MTLVYQSTRDANNTVTASQAILQGLATDGGLFTPDTYPKVDLNF
                     DKLKDASYQEVAKLVLSAFLDDFTVEELDYCINNAYDSKFDTPAIAPLVKLDGQYNLE
                     LFHGSTIAFKDMALSILPYFMTTAAKKHGLENKIVILTATSGDTGKAAMAGFANVPGT
                     EIIVFYPKDGVSKIQELQMTTQTGDNTHVIAIDGNFDDAQTNVKHMFNDVALREKLTT
                     NKLQFSSANSMNIGRLVPQIVYYVYAYAQLVKTGEIVAGEKVNFTVPTGNFGNILAAF
                     YAKQIGLPVGKLICASNDNNVLTDFFKTRVYDKKREFKVTTSPSMDILVSSNLERLIF
                     HLLGNNAEKTTELMNALNTQGQYKLTDFDAEILDLFAAEYATEEETAAEIKRVCELDS
                     YIEDPHTAVASAVYKKYQSATGDVTKTVIASTASPYKFPVVAVEAVTGKAGLTDFEAL
                     AQLHEISGVAVPPAVDGLEIAPIRHKTTVAAADMQAAVEAYLGL"
     gene            3434..4714
                     /locus_tag="VVR63_000533"
     CDS             3434..4714
                     /locus_tag="VVR63_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEU6128579.1"
                     /translation="MFKKNKDILNIALPAMGENFLQMLMGMVDSYLVAHLGLIAISGV
                     SVAGNIITIYQAIFIALGAAISSVISKSIGQKDQSKLAYHVTEALKITLLLSFLLGFL
                     SIFAGKEMIGLLGTERDVAESGGLYLSLVGGSIVLLGLMTSLGALIRATHNPRLPLYV
                     SFLSNALNILFSSLAIFVLDMGIAGVAWGTIVSRLVGLVILWSQLKLPYGKPTFGLDK
                     ELLTLALPAAGERLMMRAGDVVIIALVVSFGTEAVAGNAIGEVLTQFNYMPAFGVATA
                     TVMLLARAVGEDDWKRVASLSKQTFWLSLFLMLPLSFSIYVLGVPLTHLYTTDSLAVE
                     ASVLVTLFSLLGTPMTTGTVIYTAVWQGLGNARLPFYATSIGMWCIRIGTGYLMGIVL
                     GWGLPGIWAGSLLDNGFRWLFLRYRYQRYMSLKG"
     gene            4718..5338
                     /locus_tag="VVR63_000534"
     CDS             4718..5338
                     /locus_tag="VVR63_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEU6128580.1"
                     /translation="MQKTAFIWDLDGTLLDSYEAILSGIEETFAQFSIPYDKEKVREF
                     IFKYSVQDLLVRVAEDRNLDVEVLNQVRAQSLAEKNAQVVLMPGAREVLAWADESGIQ
                     QFIYTHKGNNAFTILKDLGVESYFTEILTSQSGFVRKPSPEAATYLLDKYQLNSDNTY
                     YIGDRTLDVEFAQNSGIQSINFLESTYEGNHRIQALADISRIFETK"
     gene            5504..6616
                     /locus_tag="VVR63_000535"
     CDS             5504..6616
                     /locus_tag="VVR63_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEU6128581.1"
                     /translation="MKKRMLLASTVALSFAPVLATQAEEVLWTARSVEQIQNDLTKTD
                     NKTSYTVQYGDTLSTIAEALGVDVTVLANLNKITNMDLIFPETVLTTTVNEAEEVTEV
                     EIQTPQADSSEEVTTATADLTTNQVTVDDQTVQVADLSQPIAEVTKTVIASEEVAPST
                     GTSVPEEQTTETTRPVEEATPQETTPAEKQETQASPQAASAVEVTTTSSEAKEVASSN
                     GATAAVSTYQPEETKIISTTYEAPAAPDYAGLAVAKSENAGLQPQTAAFKEEIANLFG
                     ITSFSGYRPGDSGDHGKGLAIDFMVPERSELGDKIAEYAIQNMASRGISYIIWKQRFY
                     APFDSKYGPANTWNPMPDRGSVTENHYDHVHVSMNG"
     gene            6936..7361
                     /locus_tag="VVR63_000536"
     CDS             6936..7361
                     /locus_tag="VVR63_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HEU6128582.1"
                     /translation="MIEIQDLLYQLRLSEQASTQLFEKRLGISLTRYQILLFLLEHSP
                     CNQMAVQERLKIDQAALTRHFKILETEGLVERHRNPENQREVLVEAAKYAKEQLVVNP
                     PLQHIRVKEEIESILTEFERTELSRLLNKLVLGIENIEI"
     gene            7372..7731
                     /locus_tag="VVR63_000537"
     CDS             7372..7731
                     /locus_tag="VVR63_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
                     /protein_id="HEU6128583.1"
                     /translation="MSIILTTIVALEHFYIFYLESIATQSDATSRVFNMEKEELAHPS
                     VSSLFKNQGIYKALLGVFLLYVIYFSQNLEIVTIFVLFVIGAATYGSLTADKKIILKQ
                     GGSAILALISILLFKYT"
     gene            7838..8482
                     /gene="pcp"
                     /locus_tag="VVR63_000538"
     CDS             7838..8482
                     /gene="pcp"
                     /locus_tag="VVR63_000538"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HEU6128584.1"
                     /translation="MKVLVTGFEPFGGEKGNPALEAIKGLPAEIHGAEVRWLEVPTVF
                     HKSAQVLEEEMNRYQPDFVLCIGQAGGRTSLTPERVTINQDDACISDNEDNQPIDRPI
                     RPDGASAYFSSLPIKAMVQAIKKEGLPASVSNTAGTFVCSHLMYQALYLVEKKSPYVK
                     AGFMHIPYMMEQVVNRPTTPAMSLVDIRRGIEAAIGAIIEHGDQELKLVGGETH"
     gene            complement(8510..9367)
                     /locus_tag="VVR63_000539"
     CDS             complement(8510..9367)
                     /locus_tag="VVR63_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HEU6128585.1"
                     /translation="MNYPKIDLKTIRQESKHFQADTPRLFLLYILPSMLVILSGFLNP
                     LSRIHGTVLEQPFFSILGQILQTYLFPLLVSFIGTILLTSSVYATLTLMKDSKTEPSV
                     KNSLALFDEERFSQTFLTLLLKRFYLFLWSIPNLLGIYLLFYSSFLAKKFVTLHPEFP
                     NLDLSSVETERFLMVFGLYFLASLILIIVGNILYIPQYYAYSQVEFLLCYSLDLGQVP
                     PRRILKTSRSFMKGYKFQHFVLDLQLLPWYFLNWITFGIASFSLLPYIQCTKIMFYRA
                     VLARKRPKA"
     gene            9497..10639
                     /gene="tgt"
                     /locus_tag="VVR63_000540"
     CDS             9497..10639
                     /gene="tgt"
                     /locus_tag="VVR63_000540"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HEU6128586.1"
                     /translation="MSDSPIKYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEMGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAHDLVSMDFSGYSI
                     GGLAVGETHEEMNAVLDFTTQLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAQFAEDFTPLDPECDCYTCNNYTRAYLRHLLKADETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREYFVEKYGYNKSGRNF"
     gene            10740..12557
                     /locus_tag="VVR63_000541"
     CDS             10740..12557
                     /locus_tag="VVR63_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HEU6128587.1"
                     /translation="MRIKWFSLIRITGLLLVLLYHFFQTIFPGGFFGVDVFFTFSGFL
                     ITALLIEEFSKNHEIDLIGFFRRRFYRIVPPVVLMVLVTMPFTFLVRQDYVAGIGGQI
                     AGVLGFMTNFYELLTGGNYESQFIPHLFVHNWSLAVEVHYYILWGLAVWFLSKQSRSN
                     GQLRGMVFLLSATAFLISFFSMFIGSFLVTSYSSVYFSSLTHVYPFFLGSILATIVGV
                     RQTTSLVKQLDKIWDLRKTLLVFAGGFGFLLILTFFVKFTYLFAYLIGFLLASLAALA
                     MILAARVLHEKTPNVQEPKMISFLADTSYAVYLFHWPFYIIFSQLTSNLLAVLLTLIC
                     SYGFASLSFYVLEPWIAGKNTPVLQTLRPLPYIHAILATSTGILVFIVFLVTLLAPQV
                     GAFETDLTVNGLKQAASNIAQTKVMAERAEADSLGIADGTMLIGDSVALRANTALQTA
                     LPGAQINAQVSRTTKTANEIMLNNSQNKFLPKMVVIATGVNNPENYKEDWDSIVKNLP
                     KGHHMILVTPYEGDKTKETYAIVEKAAAYMRELAEKTPYITVADWNQVAKEHPEIWAG
                     TDQVHFGSDTSTIEAGAKLYAETIATALQTAQDKPVKSK"
     gene            12710..13861
                     /gene="nagA"
                     /locus_tag="VVR63_000542"
     CDS             12710..13861
                     /gene="nagA"
                     /locus_tag="VVR63_000542"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HEU6128588.1"
                     /translation="MPNYIKADQFFYPHGVRRGGYLELVDGKFGKHVEQIPEGAEVID
                     YTGYSIAPGLVDTHIHGYAGVDVMDNNIEGTLHTMSEGLLSTGVTSFLPTTLTATYEQ
                     LLAVTENLGNHYKEATGAKIRGIYYEGPYFTETFKGAQNPTYMRDPGVEEFHSWQKAA
                     NGLLNKIALAPERDGVEDFVRTVTGEGVTVALGHSNATFDEAKKAVDAGASVWVHAYN
                     GMRGLTHRELGMVGAMYQLPHTYAELICDGHHVDPKACEILIKQKGTENIALITDCMT
                     AGGLEDGDYMLGEFPVVVANGTARLKSTGNLAGSILKLKDGLKNVVEWGIANPHEAVM
                     MASFNPAKSVHIDDVCGQIREGYDADFIVLDKDLELVATYLDGVKRYQA"
     gene            14024..15082
                     /locus_tag="VVR63_000543"
     CDS             14024..15082
                     /locus_tag="VVR63_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HEU6128589.1"
                     /translation="MKAYTYVKPGLASFVDVDKPVIRKPTDAIVRIVKTTICGTDLHI
                     IKGDVPTCQSGTILGHEGIGIVEEVGEGVSNFKKGDKVLISCVCACGKCYYCKKGIYA
                     HCEDEGGWIFGHLIDGMQAEYLRVPHADNTLYHTPEDLSDEALVMLSDILPTGYEIGV
                     LKGKVEPGCSVAIIGSGPVGLAALLTAQFYSPAKLIMVDLDDNRLETALSFGATHKVN
                     SSDPEKAIKEIYDLTDGRGVDVAIEAVGIPATFDFCQKIIGVDGTVANCGVHGKPVEF
                     DLDKLWIRNINVTTGLVSTNTTPQLLKALESHKIEPEKLVTHYFKLSEIEKAYEVFSK
                     AADHHAIKVIIENDISEA"
     gene            15233..15598
                     /locus_tag="VVR63_000544"
     CDS             15233..15598
                     /locus_tag="VVR63_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HEU6128590.1"
                     /translation="MYRVIEMYGDFEPWWFLEGWEEDIVASRKFDQYYDALKYYKTCW
                     FRLEQESPLYKSRSDLMTIFWDPEDQRWCDECDEYLQQYHSLALLQDEQVIPDEKLRS
                     GYEKQTSQERNRSCRMKLK"
     gene            15674..16615
                     /locus_tag="VVR63_000545"
     CDS             15674..16615
                     /locus_tag="VVR63_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000249584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HEU6128591.1"
                     /translation="MVQEIAQEIIRSARKKGTQDIYFVPKLDAYELHMRVGDERCKIG
                     SYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYAYDQKMASLRLSTVGDYRGHESL
                     VIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
                     VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDSETARAVV
                     RASLTGATVFSTIHAKSIRGVYERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFAS
                     RDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS"
     gene            16563..17579
                     /locus_tag="VVR63_000546"
     CDS             16563..17579
                     /locus_tag="VVR63_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HEU6128592.1"
                     /translation="MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLD
                     RSALLDKQCVIQMRAGLSQGKSFSEMMESLGCSSTIVTQLSLAEVHGNLHLSLGKIEE
                     YLDNLAKVKKKLIEVATYPLILLGFLLLIMLGLRNYLLPQLDSSNIATRIIGNLPQIF
                     LGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQ
                     GMELTQIFQMMQEQGSQLFKEIGQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGE
                     VKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIVLLYAAMLMPMYQNM
                     EVNF"
     gene            17581..17907
                     /locus_tag="VVR63_000547"
     CDS             17581..17907
                     /locus_tag="VVR63_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HEU6128593.1"
                     /translation="MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKE
                     AVNDKGKAAVVKVVESQAELYSLDKNEDATLSKLQGDGRITEEQVKAYNEYYTKNGGA
                     NRKVND"
     gene            17900..18304
                     /locus_tag="VVR63_000548"
     CDS             17900..18304
                     /locus_tag="VVR63_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HEU6128594.1"
                     /translation="MIKAFTMLESLLVLGLVSILALGLSSSVQSTFAAVEEQIFFMEF
                     EELYRETQKRSVASQQKTSLNLDGQTLSNGSQKLTVPKGIQAPSGQSITFDRAGGNSS
                     LAKVEFQTSKGAIRYQLYLGNGKIKRIKETKN"
     gene            18309..18569
                     /locus_tag="VVR63_000549"
     CDS             18309..18569
                     /locus_tag="VVR63_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6128595.1"
                     /translation="MILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVA
                     KMALQTGQNQVSINGVEIQVFSSEKGLEVYHGSEQLLAIKEP"
     gene            18532..18993
                     /locus_tag="VVR63_000550"
     CDS             18532..18993
                     /locus_tag="VVR63_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000250539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEU6128596.1"
                     /translation="MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQTMSQLLI
                     SEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVEGNRLYMKQDGKDIAIGKSKSDDFR
                     KTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEES"
     gene            18971..19417
                     /locus_tag="VVR63_000551"
     CDS             18971..19417
                     /locus_tag="VVR63_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001851880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEU6128597.1"
                     /translation="MWKKKKVKAGVLLYAVTIAAIFSLLLQFYLNRQIAHYQDYALNK
                     EKLVAFAMAKRTKDKAEQESGEQVFNLGQVSYQNKKTSLVTTVRTSKSQYEFLFPSVK
                     IKEEKRDKKEEVATDSSEKAEKKNQKRSLKRKRIPSQFNYNALNPE"
     gene            19520..20114
                     /locus_tag="VVR63_000552"
                     /pseudo
     CDS             19520..20114
                     /locus_tag="VVR63_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679792.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
     gene            20175..21128
                     /locus_tag="VVR63_000553"
     CDS             20175..21128
                     /locus_tag="VVR63_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEU6128598.1"
                     /translation="MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGET
                     ELNQVKDNNQTLKRLALRKEEWLKTYQFLLMKAGQTEPLQANHQFTPDAIALLLVFIV
                     EELFKEEEITILEMGSGMGILGATFLTSLDKKVDYLGMEVDDLLIDLAASMADVIGLQ
                     AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGF
                     KYLKSDGYAIFLAPSDLLTSPQSDLLKVWLKEEASLVAMISLPENLFANAKQSKTIFI
                     LQKKSEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI"
     gene            21179..22369
                     /locus_tag="VVR63_000554"
     CDS             21179..22369
                     /locus_tag="VVR63_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HEU6128599.1"
                     /translation="MTKTIAINAGSSSLKWQLYLMPEEKVLAKGLIERIGLKDSISTV
                     KFDGRSEQQILDIENHTQAVKILLDDLIRFDIIKAYDEITGVGHRVVAGGEYFKESTV
                     VEGDVLEKVEELSLLAPLHNPANAAGVRAFKELLPDITSVVVFDTSFHTSMPEKAYRY
                     PLPTKYYTENKVRKYGAHGTSHQFVAGEAAKLLGRPLEDLKLITCHIGNGGSITAVKA
                     GKSVDTSMGFTPLGGIMMGTRTGDIDPAIIPYLMQYTEDFNTPEDISRVLNRESGLLG
                     VSANSSDMRDIEAAVAEGNHEASLAYEMYVDRIQKHIGQYLAVLNGADAIVFTAGVGE
                     NAESFRRDVISGISWFGCDVDDEKNVFGVTGDISTEAAKIRVLVIPTDEELVIARDVE
                     RLKK"
     gene            22518..22889
                     /gene="rnpA"
                     /locus_tag="VVR63_000555"
     CDS             22518..22889
                     /gene="rnpA"
                     /locus_tag="VVR63_000555"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HEU6128600.1"
                     /translation="MKKNFRVKREKDFKAIFKEGTSFANRKFVVYQLENQKNHFRVGL
                     SVSKKLGNAVTRNQIKRRIRHIIQNAKGSLVEDVDFVVIARKGVETLGYAEMEKNLLH
                     VLKLSKIYREGNGSEKETKVD"
     gene            22864..23688
                     /locus_tag="VVR63_000556"
     CDS             22864..23688
                     /locus_tag="VVR63_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEU6128601.1"
                     /translation="MKKKLKLTSLLGLSLLIMTACATNGVTSDITAESADFWSKLVYF
                     FAEIIRFLSFDISIGVGIILFTVLIRTVLLPVFQVQMVASRKMQEAQPRIKALREQYP
                     GRDMESRTKLEQEMRKVFKEMGVRQSDSLWPILIQMPVILALFQALSRVDFLKTGHFL
                     WINLGSVDTTLVLPILAAVFTFLSTWLSNKALSERNGATTAMMYGIPVLIFIFAVYAP
                     GGVALYWTVSNAYQVLQTYFLNNPFKIIAEREAVVQAQKDLENRKRKAKKKAQKTK"
     gene            23707..24693
                     /locus_tag="VVR63_000557"
     CDS             23707..24693
                     /locus_tag="VVR63_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HEU6128602.1"
                     /translation="MVVFTGSTVEEAIQKGLKELDIPRMKAHIKVISREKKGFLGLFG
                     KKPAQVDIEAISETTVVKANQQVVKGVPKKINDLNEPVKTVSEETVDLGHVVDAIKKI
                     EEEGQGISDEVKAEILKHERHASTILEETGHIEILNELQIEEAMREEAGADDLETEQD
                     QTENQDLKEMGLKVEQSYDIAQVATDVTAYVQTIIDDMDVEATLSNDYNRRSINLQID
                     TNEPGRIIGYHGKVLKALQLLAQNYLYNCYSRTFYITINVNDYVEHRAEVLQTYAQKL
                     AIRVLEEGRSHQTDPMSNSERKIIHRIISRMDGVTSYSEGDEPNRYVVVDTE"
     gene            24744..25367
                     /locus_tag="VVR63_000558"
     CDS             24744..25367
                     /locus_tag="VVR63_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P"
                     /protein_id="HEU6128603.1"
                     /translation="MLNKIRDYLDFSGLQYRSPDKAGAEREKMLAFRHKGQEARKAFT
                     ELAKVFQANHPEWQLQQTSQWMNQAQRLRPHFWVYLQREGKVTEPMIALRLYGNPSDF
                     GISLEVSFIERKKDEQTLGKQAKVLDIPTVKGIYYLTYSNGQSQRWEANEEKRRTLRE
                     KVRSQEVRKVLVKVDVPMTENSSEEEIVEGLLKSYSKILPYYLATRK"
     gene            25498..26955
                     /locus_tag="VVR63_000559"
     CDS             25498..26955
                     /locus_tag="VVR63_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEU6128604.1"
                     /translation="MEVVSSVLNWFSSNILQNPAFFVGLLVLIGYALLKKPAHDVFSG
                     FVKATVGYMLLNVGAGGLVTTFRPILAALNYKFQIGAAVIDPYFGLAAANNKIAAEFP
                     DFVGTATTALLIGFGINILLVALRKITKVRTLFITGHIMVQQAATVSLMVLFLVPQLR
                     NAYGTAAIGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAGRFGK
                     KEESLDNLKLPKFLLIFHDTVVASATLMLVFFGAILLILGPDIMSNKEVITSGTLFNP
                     AKQDFFMYIIQTAFTFSVYLFVLMQGVRMFVSELTNAFQGISNKLLPGSFPAVDVAAS
                     YGFGSPNAVLSGFTFGLIGQLITIVLLIVFKNPILIITGFVPVFFDNAAIAVYADKRG
                     GWKAAVILSFISGVLQVALGALCVALLDLASYGGYHGNIDFEFPWLGFGYIFKYLGIV
                     GYVLVCLFLLVIPQLQFAKAKDKEKYYNGEVQEEA"
     gene            26978..27259
                     /locus_tag="VVR63_000560"
     CDS             26978..27259
                     /locus_tag="VVR63_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU6128605.1"
                     /translation="MVKVLAACGNGMGSSMVIKMKVENALRKLNQTDFTVNSCSVGEA
                     KGLAVGYDIVIASLHLIQELEGRTNGKLIGLDNLMDDKEITEKLSQALQ"
     gene            27336..27821
                     /locus_tag="VVR63_000561"
     CDS             27336..27821
                     /locus_tag="VVR63_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU6128606.1"
                     /translation="MNLKQALIDNDSIRLGLEANNWKEAVKVAVDPLIESGAILPEYY
                     DAIIESTEEYGPYYILMPGMAMPHARPEAGVQSDAFSLITLQNPVVFSDGKEVSVLLA
                     LAATSSKIHTSVAIPQIIALFELEDSIARLQACQTKEDVLAMIEESKDSPYLEGLDLE
                     S"
     gene            27838..28503
                     /locus_tag="VVR63_000562"
     CDS             27838..28503
                     /locus_tag="VVR63_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HEU6128607.1"
                     /translation="MTKRIPNLQVALDHSDLQGAIKAAVSVGQEVDIIEAGTVCLLQV
                     GSELAEVLRSLFPDKIIVADTKCADAGGTVAKNNAVRGADWMTCICCATIPTMEAALK
                     AIKTERGERGEIQIELYGDWTFEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNK
                     VKKLIDMGFRVSVTGGLDVDTLKLFEGVDVFTFIAGRGITEAADPAGAARAFKDEIKR
                     IWG"
     gene            28507..29365
                     /locus_tag="VVR63_000563"
                     /pseudo
     CDS             28507..29365
                     /locus_tag="VVR63_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252119.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
     gene            29367..30071
                     /locus_tag="VVR63_000564"
     CDS             29367..30071
                     /locus_tag="VVR63_000564"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HEU6128608.1"
                     /translation="MNQVINAMRKRVCDANQSLPKHGLVKFTWGNVSEVNRELGVIVI
                     KPSGVDYDELTPENMVVTDLDGKILEGDLRPSSDLPTHVQLYKAWSEIGSVVHTHSTE
                     AVGWAQAGRDIPFYGTTHADYFYGSIPCARSLTKDEVEVAYEKDTGLVIVEEFEHRGL
                     NPVEVPGIVVRNHGPFTWGKNPENAVYHSVVLEEVSKMNRFTEQINPRVGPAPQYILE
                     KHYQRKHGPNAYYGQK"
     gene            30250..31923
                     /locus_tag="VVR63_000565"
     CDS             30250..31923
                     /locus_tag="VVR63_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEU6128609.1"
                     /translation="MVLDKASCDLLQYLMDQETSKTIMAISKDLKESRRKIYYHIDKI
                     NAALVDEALHIISIPRIGIHLTEEQRDACCKLLSEVDSYDYIMSAHERMMIMLLWIGI
                     SKERITIEKLIELTEVSRNTVLNDLNSIRYQLTLEQYQVILQVSKSQGYHLHAHPLNK
                     IQYLQSLLYHIFMEENATFVSILEDKMKERLDDECLLSVEMNQFFKEQVPLVEQDLGK
                     KINHHEITFMLQVLPYLLLSCHNVEQYQERHQDIEKEFSLIRKRIEYQVSKKLGERLF
                     QKFEISLSGLEVSLVAVLLLSYRKDLDIHAESDDFRQLKLALEEFIWYFESQIRMEIE
                     NKDDLLRNLMIHCKALLFRKTYGIFSKNPLTKQIRSKYGELFLVTRKSAEILEGAWFI
                     RLTDDDIAYLTIHIGGFLKYTPSSQKNMKKVYLVCDEGVAVSRLLLKQCKLYFPNEQI
                     DTVFTTEQFKSVEDIAQVDVVITTNDDLDSRFPILRVNPILEAEDILKMLDYLKHNIF
                     RNKSKSFSENLSSLISSYIVDSKLASKFQEEVQTLINKEIVVQAFLEDI"
     gene            32035..33126
                     /gene="ulaG"
                     /locus_tag="VVR63_000566"
     CDS             32035..33126
                     /gene="ulaG"
                     /locus_tag="VVR63_000566"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HEU6128610.1"
                     /translation="MPNVKEITRESWILATFPEWGTWLNEEIEEEVVPEGNFAMWWLG
                     NCGTWIKTPAGANVVMDLWSNRGKSTKKVKDMVRGHQMANMAGVRKLQPNLRVQPMVI
                     DPFAINELDYYLVSHFHSDHIDPYTAAAILNNPKLEHVKFIGPYHCGRIWEGWGVPKE
                     RIIVVKPGDTIELKDMKIHAVESFDRTCLVTLPVNGADETGGELAGLAVTDEEMAQKA
                     VNYIFETPGGTIYHGADSHFSNYFAKHGKDFKIDVALNNYGENPVGIQDKMTSIDLLR
                     MAENLRTKVIIPVHYDIWSNFMASTNEILELWKMRKDRLQYDFHPFIWEVGGKYTYPQ
                     DQHLVEYHHPRGFDDCFEQDSNIQFKALL"
     gene            33240..35216
                     /gene="tkt"
                     /locus_tag="VVR63_000567"
     CDS             33240..35216
                     /gene="tkt"
                     /locus_tag="VVR63_000567"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEU6128611.1"
                     /translation="MSNLSVNAIRFLGIDAINKANSGHPGVVMGAAPMAYSLFTKQLH
                     INPAQPNWINRDRFILSAGHGSMLLYALLHLSGFEDVSMDEIKSFRQWGSKTPGHPEF
                     GHTAGIDATTGPLGQGISTATGFAQAERFLAAKYNREGYNIFDHYTYVICGDGDLMEG
                     VSSEAASYAGLQKLDKLVVLYDSNDINLDGETKDSFTESVRDRYNAYGWHTALVENGT
                     DLEAIHAAIETAKASGKPSLIEVKTVIGYGSPNKQGTNAVHGAPLGADETASTRQALG
                     WDYEPFEIPEQVYADFKEHVADRGASAYQAWTKLVADYKEAHPELAAEVEAIIDGRDP
                     VEVTPADFPALENGFSQATRNSSQDALNVVAAKLPTFLGGSADLAHSNMTYIKTDGLQ
                     DDTNRLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAVRLSALQGL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRAMPNLNVFRPADARETQAAWYLAVTSEK
                     TPTALVLTRQNLTVEDGTDFDKVAKGAYVVYENAADFDTILIATGSEVNLAVSAAKEL
                     ASQGEKIRVVSMPSTDVFDKQDAAYKEEILPNAVRRRVAVEMGASQNWYKYVGLDGAV
                     LGIDTFGASAPAPKVLAEYGFTVENLVKIVRNLK"
     gene            35333..35632
                     /gene="yajC"
                     /locus_tag="VVR63_000568"
     CDS             35333..35632
                     /gene="yajC"
                     /locus_tag="VVR63_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEU6128612.1"
                     /translation="MNPNITFLIMLVGMMALMFFMQRSQKKQAQKRMESLNKLQKGYE
                     VITIGGLYGTVDEVDTEKGTIVLDVDGVYLTFELAAIKTVLPLKETASLEGAIEK"
     gene            35679..36107
                     /locus_tag="VVR63_000569"
     CDS             35679..36107
                     /locus_tag="VVR63_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HEU6128613.1"
                     /translation="MKKLVFVCLGNICRSPMAEFVMKSMTDNYEIQSRATSSWEHGNP
                     IHKGTQGIFQEYEIPYDKNKTSLQISKEDFEAFDYIIGMDASNISDLCQMCPVDCQDK
                     IYSFSSESVPDPWYTGDFEETYRRVQEGCQAWLERLEKES"
     gene            36109..36519
                     /locus_tag="VVR63_000570"
     CDS             36109..36519
                     /locus_tag="VVR63_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6128614.1"
                     /translation="MENLTNFYEKYRVYLTRPRLELLAVVTIVFCAVLVFFLNIPGKG
                     VLKLDNGTIVYDGSLVRGKMNGQGTITFQNGDQYTGGFNNGAFNGKGTFQSKEGWTYE
                     GDFVNGQAEGKGKLTTEQEVVYEGTFKQGVFQQK"
     gene            36819..39470
                     /gene="adhE"
                     /locus_tag="VVR63_000571"
                     /gene_synonym="adhC"
     CDS             36819..39470
                     /gene="adhE"
                     /locus_tag="VVR63_000571"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HEU6128615.1"
                     /translation="MADKKTVTPEEKKLVAEKHVDELVQKALVALEEMRKLDQEQVDY
                     IVAKASVAALDAHGELALHAFEETGRGVFEDKATKNLFACEHVVNNMRHTKTVGVIEE
                     DDVTGLTLIAEPVGVVCGITPTTNPTSTAIFKSLISLKTRNPIVFAFHPSAQESSAHA
                     ARIVRDAAIAAGAPENCVQWITQPSMEATSALMNHEGVATILATGGNAMVKAAYSCGK
                     PALGVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVAE
                     FKSYHTYFVNKKEKALLEEFCFGVKANSKNCAGAKLNADIVGKPATWIAEQAGFTVPE
                     GTNILAAECKEVGENEPLTREKLSPVIAVLKSESREDGITKARQMVEFNGLGHSAAIH
                     TADEELTKEFGKAVKAIRVICNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSVGDNVS
                     AINLLNIKKVGRRRNNMQWMKLPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGF
                     LDRIIEQLDLRRNKVVYQIFADVEPDPDITTVNRGTEIMRAFKPDTIIALGGGSPMDA
                     AKVMWLFYEQPEVDFRDLVQKFMDIRKRAFKFPLLGKKTKFIAIPTTSGTGSEVTPFA
                     VISDKANNRKYPIADYSLIPTVAIVDPALVLTVPGFVAADTGMDVLTHATEAYVSQMA
                     SDYTDGLALQAIKLVFENLESSVKNADFHSREKMHNASTIAGMAFANAFLGISHSMAH
                     KIGAQFHTIHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIARMLGLPA
                     STPEEGVESYAKAVYELGERIGIQMNFRDQGIDEKEWKEHSRELAFLAYEDQCSPANP
                     RLPMVDHMQEIIEDAYYGYKERPGRRK"
     gene            complement(40337..40645)
                     /locus_tag="VVR63_000572"
     CDS             complement(40337..40645)
                     /locus_tag="VVR63_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEU6128616.1"
                     /translation="MTEEMEYICFQLIANSGAAKSSFIEAIQLAKAGNLKEAKIKVEE
                     AEDSLVEAHKIHSNLIQKEATGEKIGFSLLFMHAEDQMASTEIIQLLSKEFIDLYQNK
                     "
     gene            complement(40642..40950)
                     /locus_tag="VVR63_000573"
     CDS             complement(40642..40950)
                     /locus_tag="VVR63_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU6128617.1"
                     /translation="MKQILLVCNAGMSTSMLVKKMQQSATERGIEISIQAKSMTEAKK
                     NIHEADVILIGPQIRYELLAVKEIAGNIPVDTIDMRDYGMMNGAKVLEQALEWIGEIR
                     "
     gene            complement(40955..42250)
                     /locus_tag="VVR63_000574"
     CDS             complement(40955..42250)
                     /locus_tag="VVR63_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEU6128618.1"
                     /translation="MKNSKFIDQFATFAGKLGNQIHLKTLRDAFVTVMPLYILAGLIV
                     LLNNTVFKWIFQGDTLTRFQYWGITIANGTLSISGMIIAVMVGYFLAKNRDFENPLAA
                     SMLSLVSLIVMMPNTVSVVPDGAKDAVNISGVLSFNNTGTGAMFAGVIVAIIATELFI
                     ELSNVKALQMNLGENIPPAVSRSFSVLLPVMTVISLFGVVSALLFNITGMNLISIITI
                     FIQEPIRHIGTSLIGVIIIYSLGNMLWLFGIHQAVIYSAILEPLLLINITENITAANN
                     GQAIPHIINLSQIQTFALMGGSGSTLCLLIATFLVSRNAVSKNVAKLSFGPGIFNINE
                     PVLFGYPIVYNISLAIPFITVPVLGILISYLATVTGFMSPAFIQVPWTTPVFLNAWLA
                     TAGDVRAVLVQFIIFALGVLLYIPFIKVNDKVVEQEMEG"
     gene            complement(42268..43677)
                     /locus_tag="VVR63_000575"
     CDS             complement(42268..43677)
                     /locus_tag="VVR63_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEU6128619.1"
                     /translation="MKKKLVFPNLFWWGAASSGPQTEGQYGKVHENVMDYWFKTHPED
                     FFDNVGPLVASNFFHTYTEDFHLMKEIGVNSFRTSIQWSRLIKNLETGEPDPKGIAFY
                     NAIIEEAKKNQMDLVMNLHHFDLPVELLQKYGGWESKHVVELFVKFAKTAFTCFGDKV
                     HYWTTFNEPMVIPEAGYLYAFHYPNLKGKGKEAVQVIYNLNLASAKVIQLYRSLGLDG
                     KIGIILNLTPAYPRSNSPEDLEASRFTDDFFNKVFLNPAVKGTFPERLVKQLERDGVL
                     WSHTEKELQLMKSNTVDFLGVNYYHPKRVQAQANPEEYQTPWMPDQYFKEYEWPERRM
                     NPYRGWEIFPKAIYDIAMIVKKEYGNIPWFISENGMGVENEARFIGENGVIDDVYRIE
                     FYEEHLRWLHKAIEEGSHCFGYHAWTAFDCWSWNNAYKNRYGFISVDLETQKRTIKRS
                     GRWYRKVSDNNGFEVEIEE"
     gene            43835..44563
                     /locus_tag="VVR63_000576"
     CDS             43835..44563
                     /locus_tag="VVR63_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEU6128620.1"
                     /translation="MSTKYLFIYNEIREKILCNKYTMNEQLPDEMTLAKQFACSRMTI
                     KKALDLLVSEGLIFRKRGQGTFVLSRGSSKRKLIVPERDIRGLTKISEDAHSTIDSRI
                     IHFKLEFANEFLAEKLQVALQSPVYNIYRLRIIDGKPYVLEQTYMSTDVIPGITEDIL
                     QKSIYNYIEGKLGLHIASATKILRASSSSENEQHYLQLLPTEPVFEVEQVAYLDNGTP
                     FEYSISRHRYDLFEFNSFALRHSS"
     gene            45023..45217
                     /locus_tag="VVR63_000577"
     CDS             45023..45217
                     /locus_tag="VVR63_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU6128621.1"
                     /translation="MKGKEYENRTVSFAISSKGEKMKVENISYRVDHRKLFDNISFDT
                     SSSDVTLITGKNGTGKSTLL"
     gene            complement(45583..46893)
                     /locus_tag="VVR63_000578"
     CDS             complement(45583..46893)
                     /locus_tag="VVR63_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HEU6128622.1"
                     /translation="MIHLIMISAIALAIGIGYRTKINIGLLAIAFSYLIATTLMGLSP
                     KELLHFWPTSLFFTIFSVSLFYNVATTNGTLDVLAQHILYRTRTHPNALYMILYLMAT
                     LLSALGAGFFTTMAVCCPLAITLCQKADKHPLIGAQAVNWGASGGANLITSSSGIVFQ
                     GLFKQMGWEEQAFSLGNHIFIVSIIYPLIVLLLLSCYSHYSKGRTNSSLTIDQPPLLS
                     KVQRQTTLLMISSMVLVWLFPLLHLIFPNIAWIATYQKTFDIGFVSILMVCLALRLKL
                     GKQEAILAKVPWATIIMLCGMSLLMSLAVKSGLVTLIGHLMTTTIPHFWLPLFFCVIA
                     GVMSLFSSTLSVVAPALFPIIAIISAQNPQIDIHLLTTATVIGALSTNISPFSSAGSL
                     IQLSLPNIEERGLAFKKQIILGVPISLSLGLLTTWILILLASLS"
     gene            47130..48002
                     /locus_tag="VVR63_000579"
     CDS             47130..48002
                     /locus_tag="VVR63_000579"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HEU6128623.1"
                     /translation="MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKV
                     SLFAKEAGVLAGLTVFQRVFTLFDAEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRSLL
                     TCERVALNFLQHLSGIASMTAAYVEALGDDCIKVFDTRKTTPNLRLFEKYAVRVGGGY
                     NHRFNLSDAILLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGA
                     DIIMLDNMSLEQIEQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAK
                     SLDFSMKGLTYLDV"
BASE COUNT        14716 a         8562 c        10502 g        14356 t
ORIGIN      
        1 tatattttgg aagggtagcg aagaggctaa acgcggcgga ctgtaaatcc gctccttcgg
       61 gttcgggggt tcgaatccct ccccttccat tttacgggca tagtttaaag gtagaactaa
      121 ggtctccaaa accttcagtg tgggttcaat tcctactgcc cgtgttaata gaattatggc
      181 gggtgtggtg aagtggttaa cacaccagat tgtggctctg gcatgcgtgg gttcgatccc
      241 catcactcgc ctattttata ttattggggt atagccaagc ggtaaggcaa ggtactttga
      301 ctccctcatg cgttggttcg aatccagcta ccccagttac tatttgccgg cgtggcggaa
      361 ttggcagacg cgctggactc aaaatccagt gtccgcaagg acgtgccggt tcgaccccgg
      421 ccgccggtat agtatagtgt taggaacgtt gttattcttc gttccttttt tatattattt
      481 ttggtataat tatagttatt caaattttat ttagattaag aaagtgtagg ggagtatgtc
      541 ttgttctatc gatttattaa aacatcggta tttgaaaaat attaaagaaa atcctgaatt
      601 gtttgtcgga attgagttgg agtatcctgt tgcaagttta gaaggggatg ctacagatgt
      661 tgaagttatg aaggatctat ttcattattt agtttctact ttggatctca ccgtagcaaa
      721 ggtagatgat tttggcaatc tgatccagtt agtagatccg ataagtcagg atgctatttt
      781 atttgaagtt tcctatacaa cgattgagtt tgcatttggt aaggctgaaa cgattcaaga
      841 ggtcgaaaat cgtttcaata attatatgaa tgtaattcag agaaagttag ctgaatcaaa
      901 tcatgctatt gttggctgtg gtatccatcc caactgggat aaaaatgaga attgtccagt
      961 ggcttatcca cgctatcaga tgttgatgga ttatttgaat ttgagtagaa atattattaa
     1021 atcagattta catcatttcc ctgaatatgg tacttttatc tgtgggagcc aggttcagct
     1081 ggatatttca aaaaccaact acttacgggt gattaatgct tttactcaaa ttgaagcggc
     1141 taaggcttat ttatttgcaa actctgaatt ttcgggtgcg gattgggata cgaaaatttc
     1201 aagggatatt ttctgggaag aatctatgca tggtatctat ccagagaatg ttggggtcaa
     1261 tgctagactc cttaatgatg aagctgattt ttttgactat ctaaatcatt ctgcgatttt
     1321 tactgcggaa cgtgatgggc agacctatta tttttatcct attcaggctg gggactattt
     1381 ggctacgtcc gaaatccaag catttgctct gaatggggat gaggttatta tttaccccca
     1441 agagaaggat tttgaaactc atcgtagtta ccagtaccaa gatttaacga ctcgaggaac
     1501 agttgagttt cgtagtgtgt gtacacagcc acttgatagg acttttgctt ctgcagcttt
     1561 tcacttggga ttattggtta atttagacaa gttagaagct tacttagaaa cagcaccttt
     1621 ctttaaagta tttggttatg attacaagtc tttaaggaga caattttcta agaaaaatct
     1681 tacagatgag gaagaaacta cgattattga attttccaaa gacttactcc tactagctga
     1741 ggagggacta gtggtgagaa ataaggaaga aatgacctat ttacagcctt tgagagaaga
     1801 attgagccta taatttctct tataaaggga gaattttctg aaaaatcatg atataatgga
     1861 cgagactata gataaaggat agagagtaat gacattagtt tatcaatcaa cgcgtgatgc
     1921 caacaataca gtaactgcca gccaagcaat tttgcaaggt ttggcgacgg acggcggttt
     1981 gtttacaccg gatacttatc caaaggtaga tttgaacttt gacaaattga aagatgcttc
     2041 ttaccaggaa gttgctaagc tagttttgtc agcattttta gatgacttta cagttgagga
     2101 gttggactac tgtatcaaca atgcctacga tagcaaattt gatactccag ctattgcacc
     2161 attagtgaaa ttagatgggc aatacaattt ggaacttttc catggttcaa cgattgcctt
     2221 taaggatatg gccttgtcta ttttgccata ctttatgacg actgctgcta agaaacatgg
     2281 tttggagaac aagattgtta tcttgacagc gacatctggt gacacgggga aagctgctat
     2341 ggcggggttt gcgaatgtgc ctggtactga gattatcgtc ttttatccaa aggatggtgt
     2401 cagcaagatt caagagttac aaatgaccac tcagactggc gacaatactc atgttattgc
     2461 tattgatggt aactttgacg atgcgcaaac aaatgtgaag cacatgttta acgacgtggc
     2521 tcttcgtgaa aaattgacta ccaacaagtt gcaattttca tcagctaact ctatgaacat
     2581 tggtcgtctg gtgccacaaa ttgtttatta tgtttatgct tacgctcaat tggttaagac
     2641 tggtgaaatt gtagctggtg aaaaggttaa cttcacagta ccaacaggaa actttggaaa
     2701 tatcttggct gccttttatg ccaaacaaat tggtttgcca gttggtaaat taatctgtgc
     2761 ttcaaatgac aacaatgttt tgacagactt ctttaaaaca cgtgtctatg acaaaaaacg
     2821 tgagtttaag gtaacaacca gcccatctat ggatatcttg gtatcttcaa acttggagcg
     2881 cttgattttc catcttttgg gaaataatgc tgaaaagaca actgaactta tgaatgcctt
     2941 gaacacgcaa ggacaatata agttgacaga ctttgatgca gagattttgg acctctttgc
     3001 agctgaatat gcgactgagg aagaaacggc agcagagatc aagcgtgttt gtgagttaga
     3061 ttcttatatc gaggaccctc atacagctgt tgcttcagca gtttataaaa aataccaatc
     3121 ggccactgga gatgtaacta agacagtgat tgcttcaaca gctagtccat acaagttccc
     3181 agtagttgca gtagaagctg taactggaaa agcaggttta acagactttg aagccttggc
     3241 tcaattacat gaaatctcag gcgttgcagt gccaccagca gttgatgggc ttgaaatagc
     3301 tccaattcgt cacaagacaa cagtggcagc tgctgacatg caagcagcgg ttgaggctta
     3361 tttaggactt taagacagag ggagcaaact cggttgggaa accaactgag tttcttttca
     3421 tcaggaggag agattgttta agaaaaataa agacattctt aatattgcat tgccagctat
     3481 gggtgaaaac tttttgcaga tgctaatggg aatggtggac agttatttgg ttgctcattt
     3541 aggattgata gctatttcag gggtttcagt agctggtaat attatcacca tttatcaggc
     3601 gattttcatc gctctgggag ctgctatttc cagtgttatt tcaaaaagca tagggcagaa
     3661 agaccagtcg aagttggcct atcatgtgac tgaggcgttg aagattacct tactattaag
     3721 tttcctttta ggatttttgt ccatcttcgc tgggaaagag atgataggac ttttggggac
     3781 ggagagggat gtagctgaga gtggtggact gtatctatct ttggtaggcg gatcgattgt
     3841 tctcttaggt ttaatgacta gtctaggagc cttgattcgt gcaacgcata atccacgtct
     3901 gcctctctat gttagttttt tatccaatgc cttgaatatt cttttttcaa gtctagctat
     3961 ttttgttctg gatatgggga tagctggtgt tgcttggggg acaattgtgt ctcgtttggt
     4021 tggtcttgtg attttgtggt cacaattaaa actgccttat gggaagccaa cttttggttt
     4081 agataaggaa ctgttgacct tggctttacc agcagctgga gagcgactta tgatgagggc
     4141 tggagatgta gtgatcattg ccttggtcgt ttcttttggg acggaggcag ttgctgggaa
     4201 tgcaatcgga gaagtcttga cccagtttaa ctatatgcct gcctttggcg tcgctacggc
     4261 aacggtcatg ctgttggccc gagcagttgg agaggatgat tggaaaagag ttgctagttt
     4321 gagtaaacaa accttttggc tttctctgtt cctcatgttg cccctgtcct ttagtatata
     4381 tgtcttgggt gtaccattaa ctcatctcta tacgactgat tctctagcgg tggaggctag
     4441 tgttctagtg acactgtttt cactacttgg gacccctatg acgacaggaa cagtcatcta
     4501 tacggcagtc tggcagggat taggaaatgc acgcctccct ttttatgcga caagtatagg
     4561 aatgtggtgt atccgcattg ggacaggata tctgatgggg attgtgcttg gttggggctt
     4621 gcctggtatt tgggcagggt ctctcttgga taatggtttt cgctggttat ttctacgcta
     4681 tcgttaccag cgctatatga gcttgaaagg ataggaaatg caaaaaacag cttttatttg
     4741 ggatttagac gggactttat tggactctta cgaagcgatt ttatcaggga ttgaggagac
     4801 ttttgctcag ttttctattc cttatgataa ggagaaggtg agagagttta tcttcaagta
     4861 ttcggtgcaa gatttgcttg tgcgggtggc agaagataga aatctggatg ttgaggtgct
     4921 aaatcaggtg cgtgcccaga gtctggctga gaagaatgct caggtagttt tgatgccagg
     4981 tgcgcgtgag gtgctagctt gggcagacga atcaggaatt cagcagttta tatatactca
     5041 taaggggaac aacgctttta ccattctcaa ggacttgggg gtggaatcct attttacaga
     5101 gattttaacc agtcagagtg gctttgtgcg gaagccaagt ccagaagcgg ctacctatct
     5161 gctagataag tatcagttga attctgataa tacttattat ataggggatc ggactctgga
     5221 tgtggaattt gcccagaata gtgggattca aagcatcaac tttttagagt ctacttatga
     5281 agggaatcac aggattcaag cgttagcaga tatttcccgt atttttgaga ctaagtgata
     5341 aaaagattgt gtcagttttg tgacagagac ctaacaaact atttcaagta acctagtttg
     5401 ttacaaggaa tagacagttc tgttaaatag gcccgagagg gctttttttc tacatttttt
     5461 gtgttatgat agacaggtac tcatttgaaa ggaatttgaa agaatgaaga aaagaatgtt
     5521 attagcgtca acagtagcct tgtcatttgc cccagtattg gcaactcaag cagaagaagt
     5581 tctttggact gcacgtagtg ttgagcaaat ccaaaacgat ttgactaaaa cggacaacaa
     5641 aacaagttat accgtacagt atggtgatac tttgagcacc attgcagaag ccttgggtgt
     5701 agatgtaaca gtgcttgcga atctgaacaa aatcactaat atggacttga ttttcccaga
     5761 aactgttttg acaacgactg tcaatgaagc agaagaagta acagaagttg aaatccaaac
     5821 acctcaagca gactctagtg aagaagtgac aactgcgaca gcagatttga ccactaatca
     5881 agtgaccgtt gatgatcaaa ctgttcaggt tgcagacctt tctcaaccaa ttgcagaagt
     5941 tacaaagaca gtgattgctt ctgaagaagt ggcaccatct acgggcactt ctgtcccaga
     6001 ggagcaaacg accgaaacaa ctcgcccagt tgaagaagca actcctcagg aaacgactcc
     6061 agctgagaag caggaaacac aagcaagccc tcaagctgca tcagcagtgg aagtaactac
     6121 aacaagttca gaagcaaaag aagtagcatc atcaaatgga gctacagcag cagtttctac
     6181 ttatcaacca gaagagacga aaataatttc aacaacttac gaggctccag ctgcgcccga
     6241 ttatgctgga cttgcagtag caaaatctga aaatgcaggt cttcaaccac aaacagctgc
     6301 ctttaaagaa gaaattgcta acttgtttgg cattacatcc tttagtggtt atcgtccagg
     6361 agacagtgga gatcacggaa aaggtttggc tatcgacttt atggtaccag aacgttcaga
     6421 attaggggat aagattgcgg aatatgctat tcaaaatatg gccagccgtg gcattagtta
     6481 catcatctgg aaacaacgtt tctatgctcc attcgatagc aaatatgggc cagctaacac
     6541 ttggaaccca atgccagacc gtggtagtgt gacagaaaat cactatgatc acgttcacgt
     6601 ttcaatgaat ggataaaccc gacttgataa catcattttg acgaatgaga tctagctttc
     6661 gtgatggaaa gcgattctcg ttcgtttttt ctttgtcata ctcttcgaaa atctcttcaa
     6721 accacgtcag ttttatctga aacttcaaag ctgtgctttg agcaacctgc gactagcttc
     6781 ctagtttgct ttttgatttt cattgagtat caatttgaat ggaaaatgga aagttatcat
     6841 cttgtaatga gttaagcaac attcttgcaa tctattttac tttatatcac aattgattgg
     6901 tcaactattg ataagtcaat ggataggagg aagaaatgat agagattcaa gatttactgt
     6961 atcaactccg cttgtctgag caagcgagta cgcaattgtt tgaaaaaagg cttgggatta
     7021 gtttgacacg gtatcagatt ttactgtttt tgctggagca ttctccttgt aaccaaatgg
     7081 cggttcagga gcgtttgaaa attgatcagg ctgctttgac acggcatttc aaaattttgg
     7141 aaacggaagg tttggtggag cgtcatcgta atcctgaaaa tcagcgggaa gtgttggtag
     7201 aggctgcgaa gtatgccaag gagcagttag tggtgaatcc ccctctgcaa catatcaggg
     7261 ttaaggaaga gatagaaagt atcttaacag agtttgagag aacagaactc agccgtttat
     7321 taaataaatt ggttttgggt attgaaaata tagaaattta aggagaaata gatgtcaatt
     7381 attttaacaa cgatcgttgc tttggagcat ttttacattt tttatttgga aagtattgcc
     7441 acgcaatcag atgcgactag tcgtgtattt aatatggaaa aggaagaatt ggctcatccg
     7501 tcagtaagtt cattgttcaa aaatcaagga atttataagg ctctgctagg agtctttctc
     7561 ttgtatgtca tttatttctc acagaattta gaaattgtga ctatttttgt cttatttgtg
     7621 attggtgctg cgacttacgg ctctttaaca gcggataaaa aaattatttt gaaacaaggt
     7681 ggatcagcta ttttggcctt gattagtatt ttactcttta aatacacttg aaggtcgatt
     7741 ctaatctcgc taatcctttt taatccagaa taagggaaat atgttatact tgtttttaag
     7801 aaaaaagtct cattgaattg gttttgagga gttagaaatg aaagtattag tgacaggttt
     7861 tgagcccttt ggaggggaaa agggcaatcc agctttggag gccattaaag gtttaccagc
     7921 tgaaatccat ggtgctgagg tccgttggct agaggtgccg acagtttttc acaaatctgc
     7981 tcaagtattg gaagaagaga tgaatcgtta tcaacctgac tttgtccttt gtattgggca
     8041 agctggtgga agaactagtt tgacacctga acgagtgacc attaatcaag acgatgcatg
     8101 catttctgat aacgaagata atcaaccgat tgaccgtccc attcgcccag atggtgcttc
     8161 ggcctacttt agtagtttgc cgattaaagc gatggttcaa gctataaaaa aagagggctt
     8221 accggcctct gtttccaata cggcagggac ttttgtctgc agccatttga tgtatcaggc
     8281 tctctatttg gtagaaaaga aatctccata tgttaaggca ggttttatgc atattcctta
     8341 tatgatggaa caggtggtga acagaccgac tactccagct atgagtttag tggatattcg
     8401 gcgagggata gaagcagcaa tcggcgctat aatagaacat ggagatcagg aactcaagtt
     8461 ggtaggcgga gaaactcatt gatagaaaaa agcttgaggg gaaaaacctt caagcttttg
     8521 gacgttttcg ggccaatact gctcggtaaa acataatttt agtgcattgg atataaggta
     8581 ggagtgaaaa actagcaatg ccaaaggtaa tccaattgag gaagtaccaa ggaagaagct
     8641 gtaaatctag gacaaagtgc tggaacttgt agcccttcat aaaggaacgg ctagttttta
     8701 ggattcgtct tggtgggacc tgtcctaggt ctagactata acagagaaga aattccacct
     8761 gtgaataggc ataatactgt ggaatataga ggatatttcc tacaatgatc aagatgagac
     8821 ttgcaagaaa gtagagtcca aagaccatga ggaaacgctc ggtttcaact gatgagagat
     8881 ctagatttgg aaactcagga tgtagggtga cgaatttttt ggctaaaaag ctactataaa
     8941 agaggaggta aatcccaagt aaattaggga tactccataa aaagagatag aaacgtttga
     9001 gaagtagggt caaaaaggtt tgagaaaagc gctcctcatc aaagagagct aggctgtttt
     9061 ttacagatgg ctccgtttta gaatctttca tgagtgtcag tgttgcatag acggaactgg
     9121 tcaaaagaat agtcccgata aaggagacta gtagaggaaa gaggtaggtt tgaagtattt
     9181 ggccaagtat gctgaaaaat ggctgttcta aaacagtccc gtggatccga gataagggat
     9241 taagaaaacc agataagatg accagcatac tgggaaggat atagaggaga aagagacggg
     9301 gggtgtcagc ctgaaaatgt tttgactcct gacgaattgt ttttaaatca atttttggat
     9361 agttcattct cttattatac catagttctt atacatagtt cgtgacagtt cctacttttt
     9421 ttgataaaat catacagtgt gtccttgggc acactgtatg aactgggact gtctttccca
     9481 gcttcggagg taaaaaatgt cagattcacc aatcaaatat cgtttgatta agaaagaaaa
     9541 acacacagga gctcgtctgg gagaaatcat cactccccac ggtacctttc cgacacctat
     9601 gtttatgcca gttgggacac aagccactgt caaaactcag tcacctgaag aattgaagga
     9661 gatgggttcg ggaattatcc tatcaaacac ctatcatctc tggcttcgcc ctggagatga
     9721 actcattgca cgcgctggtg gtctccacaa gttcatgaat tgggaccagc ctatcttgac
     9781 agatagtggt ggttttcagg tttattcttt agcagatagc cgtaatatca cagaagaagg
     9841 agtaaccttt aaaaatcatc taaatggttc taagatgttc ctatccccag aaaaagccat
     9901 ctctattcag aataatctgg gttcagacat catgatgtcc tttgatgaat gtcctcagtt
     9961 ttatcaacct tatgactacg ttaagaaatc gatcgagcgt accagccgtt gggctgagcg
    10021 tggtttgaag gctcaccgtc gtccacatga ccaaggtttg tttggaattg tgcaaggtgc
    10081 aggatttgaa gaccttcgcc gccaatcagc tcatgatctt gtcagcatgg atttctcagg
    10141 ctactctatc ggtggtttgg cagtgggaga aacccatgaa gagatgaatg cggtcttgga
    10201 ctttacaact caactgctac ctgaaaataa acctcgttat ctgatgggtg tgggagcgcc
    10261 agatagcttg atcgatgggg tcattcgtgg ggtggatatg tttgactgtg tcttaccgac
    10321 tcgaattgct cgtaacggga cttgtatgac cagtcaagga cgtttggttg tgaaaaatgc
    10381 ccagtttgct gaggacttta cgccactgga tcctgagtgt gactgctaca catgtaataa
    10441 ctatacacgc gcttaccttc gtcacctgct caaggctgat gaaacctttg gtatccgctt
    10501 gactagctac cacaatcttt acttcttgct taacctgatg aagcaagtgc gacaagccat
    10561 catggatgac aatctcttgg aattccgtga gtattttgtg gaaaaatatg gctataataa
    10621 gtcaggacgc aatttctaaa acggaataga tataagctaa aaatcctaag ttttctcttg
    10681 ggatttttct tctttttttg atagaataaa gtgtataatg aaagggagaa taaactcgta
    10741 tgcgcattaa atggttttcc ttgattagga ttacaggttt actactggta ctcttgtatc
    10801 atttctttca gaccatcttt cctggaggat ttttcggggt agatgtcttt ttcacatttt
    10861 caggtttcct gattacggct ctactcatcg aagaattttc taaaaatcat gagattgact
    10921 tgataggatt ttttaggaga cgcttttatc ggattgtgcc acctgtggtt ttgatggtct
    10981 tggtgaccat gccctttacc tttctagttc ggcaagatta tgtggctgga attgggggtc
    11041 agattgcggg tgtcttaggc tttatgacca acttctatga acttctaaca ggtgggaatt
    11101 atgaatctca gttcattcca catttgtttg ttcataattg gagcttggct gttgaggttc
    11161 actactatat tctatgggga ttggcagttt ggttcttatc caagcagtct agatcaaatg
    11221 gtcagttgag agggatggtc tttctcttat ctgctactgc cttcttgatt agcttcttct
    11281 ccatgtttat cggtagtttt ctagtaacct cttattcttc tgtttatttc tccagtttaa
    11341 ctcatgtcta tccattcttt ttgggaagta tcctagcaac gattgtaggc gttcgtcaga
    11401 cgacttccct agttaagcaa ttggataaaa tctgggattt acgcaagacc cttttagttt
    11461 ttgcaggagg ttttggcttc ttactcattt tgaccttctt cgtcaaattt acctatctct
    11521 ttgcctatct tattggcttc ttgcttgcca gtcttgcagc ccttgctatg attctggcgg
    11581 cgcgtgtctt acatgaaaag acacctaacg tgcaggagcc aaagatgatt agctttttag
    11641 cagatactag ctatgcagtt tatctcttcc attggccttt ctatatcatt ttctcacagt
    11701 tgacatcaaa tcttcttgct gtattactga ctctgatttg ttcttatggc tttgccagtc
    11761 tttcatttta tgtgttggaa ccttggattg caggaaagaa cacacctgtt ttacaaactc
    11821 ttcgtcccct gccttatatt cacgcaattc ttgcaacaag tacaggaatc ttggttttca
    11881 ttgttttctt agtgacttta ttggcaccac aagtgggagc gtttgagaca gacttaactg
    11941 tcaatggctt gaagcaagct gctagtaata ttgcccaaac aaaagtgatg gcagaacgag
    12001 cagaagctga tagtttgggg attgctgatg gtactatgtt aattggtgat tcagtggctt
    12061 taagggcaaa tacagccctg cagacagctc ttcctggagc acaaattaac gcgcaggtca
    12121 gcagaacaac caagactgcc aatgaaatca tgctaaacaa tagccagaat aaatttttac
    12181 ctaagatggt ggtcattgcg actggggtaa ataatcctga aaattacaag gaagactggg
    12241 acagtattgt aaaaaatctt cctaagggac accatatgat tttagtcact ccttatgagg
    12301 gggataagac aaaagagacc tatgccatcg ttgagaaggc tgctgcctat atgagagaat
    12361 tggcagagaa gacaccttat atcacagttg ctgattggaa tcaagttgcg aaagagcatc
    12421 cagaaatttg ggcaggaaca gaccaagtcc atttcggaag tgacactagc actattgaag
    12481 caggagcaaa attgtatgca gagaccattg ccacagcctt gcaaacagct caagacaagc
    12541 cggttaaatc aaaataactt gtattaaaaa agagaagagt tggagaaatc cagctctttt
    12601 aaaatatctc caaaaaatag gtctatacca tttacaaata aaaaagaaag gtttataatg
    12661 taattgacat aataaattgt agaatcaatc ttttaaggag gttaacatta tgcctaacta
    12721 tattaaagcg gatcagtttt tctacccaca cggagttcgt cgaggtggtt acttggaact
    12781 tgtggacggc aagtttggga aacatgtaga gcagattcct gaaggggctg aggtgattga
    12841 ctatacaggt tatagcattg ccccaggtct tgtggatact catattcatg gatatgcagg
    12901 tgtagatgtg atggacaaca acattgaagg tacattgcat actatgagtg aaggacttct
    12961 tagtaccggt gttaccagtt tcttacccac aactttaaca gccacttatg agcaattgct
    13021 tgcagtcact gaaaatcttg gaaaccatta taaagaagca acaggtgcta agattcgtgg
    13081 gatttattat gaaggtccat atttcacaga aacttttaag ggggcacaaa atccaactta
    13141 tatgagagac ccgggtgttg aggagtttca ttcttggcaa aaagcggcaa atggcttgct
    13201 taataaaatt gcccttgcac cagaacgtga tggggtggaa gactttgttc gtacagttac
    13261 gggcgaaggt gtgacggttg ctcttggaca ttcaaacgcg acttttgatg aagccaaaaa
    13321 agcagtcgat gctggagcga gtgtttgggt gcatgcctac aatggaatgc gtgggttgac
    13381 tcaccgtgaa ttgggtatgg ttggagccat gtaccaattg ccacatacct atgcagagtt
    13441 gatctgtgat ggtcaccacg tagatccaaa ggcttgcgaa attcttatca aacaaaaagg
    13501 aacagaaaac atcgctctta tcacagactg tatgacagct gggggattgg aagacggaga
    13561 ttatatgttg ggagaattcc cagttgtcgt tgcaaatgga actgcacgcc tcaaatcgac
    13621 aggtaacttg gcaggttcta tcctcaaact caaagatggt ttgaagaatg tggtcgaatg
    13681 gggaattgcg aatccgcatg aagcagtcat gatggccagc ttcaacccag ctaaatccgt
    13741 tcacatcgat gacgtctgtg gccaaatccg tgaaggctac gacgctgact tcatcgtatt
    13801 agataaagat ttggaattgg tagcaaccta tctagatggc gtaaaacgtt atcaagcata
    13861 agagagaagg cagaagttag agactagctt ctgctttttt atacagggta ctttactggt
    13921 aaataaaaag ttaaaaaaat cacaaaaaaa gcttgaagaa acaaagaaaa aggcttacaa
    13981 ttgaactata aatattacaa ataaaaaaac ggaggagtgc tttatgaaag cctatactta
    14041 tgttaaacca ggacttgctt cttttgttga tgtagacaaa ccagttattc gcaagccaac
    14101 agacgctatt gtgcgtattg taaaaaccac tatttgtgga acagacctcc atattatcaa
    14161 aggggatgtt cctacttgcc aaagtggtac cattcttggc cacgaaggga ttgggattgt
    14221 tgaagaagtt ggggaaggag tttccaactt caaaaaaggc gacaaggtct tgatttcttg
    14281 cgtctgtgcc tgtggtaaat gctactactg taaaaaagga atttatgccc actgtgaaga
    14341 cgaagggggc tggattttcg gtcacttgat tgatggtatg caggctgaat atctacgtgt
    14401 ccctcatgca gataatactc tttaccatac tccagaagac ttgtcagatg aagctttggt
    14461 tatgctgtca gacattctgc ctactggata tgaaattggt gtcttaaaag ggaaagtaga
    14521 acctggttgc agcgtagcca ttattggttc aggtccagtt ggattggctg ctcttttaac
    14581 agcccaattc tattcaccag ctaaattgat tatggtagac ctagacgata accgcttgga
    14641 aactgcccta tcattcggtg cgactcataa ggttaattct tcagaccctg aaaaagccat
    14701 taaagaaatt tatgatttga cagatggtcg tggtgtggat gtcgctatcg aagctgttgg
    14761 tattcctgca acatttgatt tctgtcaaaa gattatcggt gtagacggaa cggttgccaa
    14821 ctgtggtgtg catggtaaac cagttgaatt cgatttagat aaactttgga ttcgcaacat
    14881 caatgtaaca actggtttgg tatctacaaa tacgactcca caattgttga aagcacttga
    14941 aagtcataag attgaaccag aaaaattggt aactcactat ttcaaactca gtgaaattga
    15001 aaaagcctat gaagtcttca gtaaggcagc agaccaccat gccattaagg tcattatcga
    15061 aaacgatatc tcagaagcct aagtagtaaa aatatttttg tacataagta aatagaaatt
    15121 cagtcatcca tcagatggct ggatttttta tcaaaaaatt aagaaatgag catatttctt
    15181 tccttgtctg gcggaattgg ttataatata cggtacaaag gaatgaatga atatgtatcg
    15241 tgttatagaa atgtacggag attttgaacc gtggtggttc ttagaaggtt gggaagaaga
    15301 tattgtagca agtagaaaat ttgaccagta ttatgatgct ctcaaatact acaaaacttg
    15361 ctggtttaga ttggaacaag aatcccctct ttataaaagt agaagcgact tgatgaccat
    15421 tttttgggac ccggaagacc aacgctggtg tgatgaatgt gatgagtatt tacaacaata
    15481 ccattctttg gctcttttgc aggatgagca ggttatccca gacgaaaaac tacgctcagg
    15541 ctatgaaaaa caaaccagtc aggaaaggaa tcgttcttgc cgtatgaaat taaaatagag
    15601 aaaagtaact tttttggagt tgcttttttt atttttctaa cgctttgcga atagtatagg
    15661 tgaggaggta agtatggttc aagaaattgc acaagaaatc attcgttcag ctcggaaaaa
    15721 agggacgcag gatatttatt ttgtccctaa gttagacgcc tatgagcttc atatgagggt
    15781 aggagacgag cgctgtaaaa ttggtagcta tgattttgaa aagtttgcag ccgttatcag
    15841 tcactttaag tttgtggcgg gtatgaatgt gggagaaaaa agacgtagtc aactgggttc
    15901 ctgtgattat gcctatgacc agaagatggc gtctctacgt ttatctactg taggcgatta
    15961 tcgggggcat gagagtttgg ttatccgttt gttgcacgat gaggagcagg acttgcattt
    16021 ttggtttcag gatattgaag aattaggcaa gcagtacagg caacggggac tctatctttt
    16081 tgctggtccg gttgggagtg gtaagacgac cttgatgcat gaattgtcca agtcactctt
    16141 taaaggacag caagttatgt ccatcgaaga tcctgtcgaa atcaagcagg acgacatgct
    16201 tcagttgcag ttgaacgaag caatcggcct aacctatgaa aatctaatca aactttcctt
    16261 gcgtcatcga ccagatctct tgattatcgg agaaattcgt gacagcgaga cggcgcgtgc
    16321 agtggtcaga gctagtttga caggtgcgac agtcttttca accattcacg ccaagagtat
    16381 ccgaggtgtt tatgagcgtc tgctggagtt gggtgtgagt gaagaagaat tggcagttgt
    16441 tctgcaagga gtctgctacc agagattaat cgggggagga ggaatcgttg actttgcaag
    16501 cagagattat caagaacacc aagcagccaa gtggaatgag caaattgacc agcttcttaa
    16561 agatggacat atcacaagtc ttcaggctga gacggaaaaa attagctaca gctaagcaaa
    16621 aaaatatcat caccctattt aacaatctct tttctagcgg ttttcatctg gtggagacta
    16681 tctccttttt agataggagt gctttgttgg acaagcagtg tgtgatccag atgcgtgcgg
    16741 gcttgtctca ggggaaatca ttctcagaaa tgatggaaag tttgggatgt tcaagtacca
    16801 ttgtcactca gttatctcta gctgaagttc atggcaatct tcacctgagt ttgggaaaga
    16861 tagaagaata tctagacaat ctggccaagg tcaagaaaaa gttaattgaa gtagcgacct
    16921 atcctttgat tttgctgggt tttcttctct taattatgct ggggctacgg aattacctgc
    16981 tcccacaact ggatagtagc aatattgcca cccgaattat cggtaatctg ccacaaattt
    17041 ttctaggcat ggtagggctt gtttccgtgc ttgccctttt agcactaact ttttataaaa
    17101 gaagttctaa gatgagtgtc ttttctatct tagcacgcct tccctttatt ggaatctttg
    17161 tgcagaccta cttgacagcc tattatgcac gtgaatgggg gaatatgatt tcacagggaa
    17221 tggagctgac gcagattttt caaatgatgc aggaacaagg ttcccagctc tttaaagaaa
    17281 tcggtcaaga tctggctcaa accctgaaaa atggccgtga attttctcag acgataggaa
    17341 cctatccttt ctttaggaag gaattgagtc tcatcataga gtatggggaa gttaagtcca
    17401 agctgggtag tgagttggaa atctatgctg aaaaaacttg ggaagccttt tttacccgag
    17461 tcaaccgcac catgaatttg gtgcagccac tggtttttat ctttgtggca ctgattatcg
    17521 ttttacttta tgcggcaatg ctcatgccca tgtatcaaaa tatggaggta aatttttaaa
    17581 atgaaaaaaa tgatgacatt cttgaaaaaa gctaaggtta aagcttttac attggtggag
    17641 atgttagtag tcttgctgat tatcagcgtg cttttcttgc tctttgtacc taatctgacc
    17701 aagcaaaaag aagcagtcaa tgacaaagga aaagcagctg ttgttaaggt ggtggaaagc
    17761 caggcagaac tttatagctt ggataaaaat gaagatgcta ctctgagcaa gttacaagga
    17821 gatgggcgca tcacggaaga acaggttaaa gcttataatg aatactatac taaaaatgga
    17881 ggggcaaatc gtaaagtcaa tgattaaggc ctttaccatg ctggaaagtc tcttggtttt
    17941 gggacttgtg agtatccttg ccttgggctt atccagctct gtccagtcca cttttgcagc
    18001 agtagaggag cagattttct ttatggagtt tgaagaactc tatcgggaaa cccaaaaacg
    18061 cagtgtagcc agtcagcaaa agactagtct aaatttagat gggcagacgc ttagcaatgg
    18121 cagtcaaaag ttgacagttc ctaaaggaat tcaggcacca tcaggccaaa gtattacatt
    18181 tgaccgagct gggggcaatt cgtccctggc taaggttgaa tttcagacca gtaaaggagc
    18241 gattcgctat caattatatc taggaaatgg aaaaattaaa cgcattaagg aaacaaaaaa
    18301 ttagggcagt gattttactg gaagcagtag tcgctctagc tatctttgcc agcattgcga
    18361 ccctcctttt gggacaaatt caaaaaaata ggcaagagga agcaaaaatc ttgcaaaagg
    18421 aagaagtctt gagggtagct aagatggccc tgcagacggg gcaaaatcag gtaagcatca
    18481 acggagttga gattcaggta ttttctagtg aaaaaggatt ggaggtctac catggttcag
    18541 aacagttgtt ggcaatcaaa gagccataag gtcaaggctt ttaccttgtt agaatccctg
    18601 cttgccctca ttgtcatcag tgggggatta ctcctttttc aaactatgag tcagctcctc
    18661 atttcagaag ttcgctacca gcaacaaagc gagcaaaagg agtggctctt gtttgtggac
    18721 caacttgagg cagaattaga ccgttcgcag ttcgaaaaag tagaaggcaa tcgcctatac
    18781 atgaagcaag atggcaagga catcgccatc ggtaagtcaa agtcagacga ttttcgtaaa
    18841 accgatgcta gtggacgggg gtatcagcct atggtttatg gcctcaaatc agctcagatt
    18901 acagaggaca atcaactggt tcattttcgt ttccagtttc aaaaaggctt agaaagggag
    18961 ttcatctatc gtgtggaaaa agaagaaagt taaggcaggt gttctcctct acgcagtcac
    19021 catagcagcc atctttagtc ttttgttgca attttatttg aaccgacaaa tcgcccacta
    19081 tcaagactat gctttaaata aagaaaaatt ggttgctttt gccatggcta aacgaaccaa
    19141 ggataaagcc gagcaagaaa gtggggaaca ggtttttaat ctaggtcagg taagctatca
    19201 aaacaagaaa acaagcttgg tgacgactgt tcgtacgtct aagagccaat atgagtttct
    19261 gtttccttca gtcaaaatca aagaagagaa aagagataaa aaggaagagg tagcgaccga
    19321 ttcaagcgaa aaagcggaga aaaaaaatca gaagagaagc ctgaaaagaa agagaattcc
    19381 tagtcaattc aactataatg cgttgaatcc agaatagtcc actgtagttt ctagaaaatt
    19441 gctggaaatg gatgttaagc tccaattcat ttgtttatat cttatttcag tttactatac
    19501 tttgtgctaa attaaagata tgaaacatga ttttaaccac aaagcagaaa ctttcgattc
    19561 ccctaaaaat atcttcctcg caaacttggt atgtcaagca gccgagaaac agattgatct
    19621 tctatcagac aaagaaattt tagatttcgg tggtggcacg ggtctattag ccttgcccct
    19681 aacccctagc caagcaggct aagtcagtca ctcttgtaga catttctgag aaaatgttgg
    19741 agcaagctcg tttgaaagtg gagcagcaag caatcaagaa tatccagttt ttggagcaag
    19801 atttaccgaa aaatcccttg gagaaagagt ttgattgcct tgctgttagt cgggttcttc
    19861 atcatatgcc tgatttggat gcggctctct cactgtttca tcaacatttg aaggaagatg
    19921 ggaaactcat cattgctgat tttaccagga cagaagctaa tcatcatgga tttgatttag
    19981 ctgaactgga aaacaagcta attgagcatg gtttttcatc tgtgcatagt cagattctct
    20041 atagtgctga agacctgttt caaggaaatc actcagaatt ctttttaata gtagcccaaa
    20101 aatcactcgc ctagtcaggg agtgattttt ctataaggat ggaaaaaaga agggaaattt
    20161 ggtaagatag gaatatggat tttgaaaaaa ttgaacaagc ttatacctat ttactagaga
    20221 atgtccaagt catccaaagt gatttggcga ccaactttta tgacgccttg gtggagcaaa
    20281 atagcatcta tctggatggt gaaactgagt taaaccaggt caaagacaac aatcaaaccc
    20341 ttaagcgttt agcactacgc aaagaagaat ggctcaagac ctaccagttt ctcttgatga
    20401 aggctgggca aacagaaccc ttgcaggcca atcaccagtt tacaccggat gctattgctt
    20461 tgcttttggt gtttattgtg gaagagttgt ttaaagagga ggaaattact atcctcgaaa
    20521 tgggttctgg gatgggaatt ctaggcgcta ctttcttgac ctcgcttgat aaaaaggtgg
    20581 attacttggg aatggaagtg gatgatttgc tgattgatct ggcagctagc atggcagatg
    20641 taattggttt gcaggctggc tttgtccaag gagatgccgt tcgcccacaa atgctcaaag
    20701 aaagcgatgt ggtcatcagt gacttgcctg tcggctatta tcctgatgat gccgttgcgt
    20761 cgcgtcatca agttgcttct agccaagaac atacttacgc tcatcacttg ctcatggaac
    20821 aagggtttaa gtaccttaag tcagatggat atgctatttt tctagctccg agtgatttgt
    20881 tgaccagtcc tcaaagtgat ttgttgaaag tctggttgaa agaggaggca agtctggttg
    20941 ctatgattag tttacctgaa aatctctttg ctaatgctaa acaatctaag actattttta
    21001 tcctacagaa gaaaagtgaa atagcagtgg agccttttgt ttatccactt gctagcttgc
    21061 aagatgcaag tgttttaatg aaatttaaag aaaattttca aaaatggact caaggtactg
    21121 aaatataaaa tagattttgt tataatagtt gaaaacgctt aaaaaggggt atcatgttat
    21181 gacaaaaaca attgcaatca atgcaggaag ttcaagtttg aaatggcaat tatacttaat
    21241 gccagaagaa aaagtattgg cgaaaggttt gattgaacgt atcggtttga aagattcaat
    21301 ttcaactgta aaatttgacg gccgttctga acaacaaatt ttggatattg aaaatcatac
    21361 acaagccgtt aaaattttat tggatgactt gattcgtttc gatattatca aggcttatga
    21421 cgagattaca ggtgttggac atcgtgttgt tgctggtgga gaatatttca aagaatcaac
    21481 agttgttgag ggagatgttt tagaaaaagt tgaagagttg agtttgttgg ctcctctaca
    21541 caacccggcc aatgcagcag gtgttcgtgc cttcaaggaa ttgttgccag acattaccag
    21601 tgtagttgtt tttgatactt ccttccacac aagtatgcca gagaaagctt atcgctaccc
    21661 tctaccaaca aaatattaca cagaaaacaa ggttcgtaaa tacggtgctc atggtacaag
    21721 tcaccagttt gtagcaggag aagctgcaaa actcttggga cgtccattag aagacttgaa
    21781 gttaattacc tgtcatattg gtaacggagg ctcaattaca gctgtgaaag ccggcaaatc
    21841 tgtagacact tctatggggt tcactcctct tggtggtatt atgatgggaa cgcgtacagg
    21901 ggatattgat ccagctatca ttccttattt aatgcaatat acagaggatt ttaacacacc
    21961 agaagatatc agtcgtgttc ttaaccgtga atcaggtctt ttgggagttt ctgctaattc
    22021 tagcgatatg cgcgatatag aagcagctgt agcagaaggg aatcacgagg ctagcttggc
    22081 ttatgaaatg tatgttgacc gtatccaaaa acatatcggt cagtaccttg cagtgctaaa
    22141 tggagcagat gccattgttt tcacagcagg tgtcggtgaa aatgcagaga gtttccgtcg
    22201 tgatgtaatc tcagggattt cgtggtttgg ttgtgatgtt gatgatgaaa agaatgtctt
    22261 tggcgttaca ggagacatct caacagaggc agctaaaatc cgtgtcttgg ttattccaac
    22321 agatgaagaa ttagtcattg cccgtgacgt tgaacgcttg aaaaaataag tgaaactaaa
    22381 aaaatattca atacaaggag ttgggaaagt tatttttcca gcttcttttt ctgatgaaat
    22441 tgtccaaaac cttgctatga ttggcttttt tgaaaaatat ggtataatag tagtaattta
    22501 atagatggag ttgagttttg aagaaaaact ttcgtgtaaa aagagagaaa gattttaagg
    22561 cgattttcaa ggaggggaca agttttgcta atcgcaaatt tgtggtctac caattagaaa
    22621 accagaaaaa ccattttcga gtaggtctat cagttagcaa aaaactgggg aatgccgtca
    22681 ctagaaatca aattaagcga cggattcggc atattatcca gaatgcaaaa gggagtctgg
    22741 tagaagatgt cgactttgtt gtcattgctc gaaaaggagt cgaaaccttg ggatacgcag
    22801 agatggagaa aaatctactc catgtattaa aattatcaaa gatttaccgg gaaggaaatg
    22861 ggagtgaaaa agaaactaaa gttgactagt ttgctaggac tgtctctgtt aatcatgaca
    22921 gcctgtgcga ctaatggggt aactagcgat attacagccg aatcggctga tttttggagt
    22981 aaattggttt acttctttgc ggaaatcatt cgctttttat cgtttgatat tagtatcgga
    23041 gtggggatta ttctctttac ggtcttgatt cgtacagtcc tcttgccagt ctttcaggtg
    23101 caaatggtgg cttctaggaa aatgcaggaa gctcagccac gcattaaggc gcttcgagaa
    23161 caatatccag gtcgagatat ggaaagcaga accaaactag agcaggaaat gcgtaaagta
    23221 tttaaagaaa tgggtgtcag acagtcagac tctctttggc cgattttgat tcagatgccg
    23281 gttattttgg ccctgttcca agccctatca agagttgact ttttaaagac aggtcatttc
    23341 ttatggatta accttggtag tgtggataca acccttgttc ttccgatttt agcagcagta
    23401 ttcacctttt taagtacttg gttgtccaac aaagctttgt ctgagcgaaa tggcgctacg
    23461 actgcgatga tgtatgggat tccagtcttg atttttatct ttgcagttta tgcgccaggt
    23521 ggagtcgccc tatactggac agtgtctaat gcttatcaag tcttgcaaac ctatttcttg
    23581 aataatccat tcaagattat cgcagagcgc gaggccgtag tacaggcaca aaaagatttg
    23641 gaaaatagaa aaagaaaagc caagaaaaag gctcagaaaa cgaaataaat aaggaggaat
    23701 ctggtaatgg tagtatttac aggttcaact gttgaagaag caatccagaa aggattgaaa
    23761 gaattagata ttccaagaat gaaggctcat atcaaagtca tttctaggga gaaaaaaggc
    23821 tttcttggtc tatttggtaa aaaaccagcc caagtggata ttgaagcgat tagtgaaacg
    23881 actgttgtta aagcaaatca acaggtagta aaaggcgttc cgaaaaaaat caatgatttg
    23941 aacgagcctg tgaagacggt tagtgaagaa accgttgacc ttggtcatgt ggttgatgct
    24001 attaaaaaaa tagaggaaga aggtcaaggt atttctgatg aagtcaaggc tgaaatctta
    24061 aaacatgaaa gacatgccag cactatctta gaagaaactg gtcacattga gattttaaat
    24121 gaacttcaaa tcgaggaagc gatgagggaa gaagcaggcg ctgatgacct tgaaactgag
    24181 caagatcaaa ctgaaaatca agacttgaaa gagatgggct tgaaggtcga gcaaagttat
    24241 gatattgccc aggtggctac ggatgtgact gcttatgttc aaacgattat tgatgacatg
    24301 gatgttgagg ctacactttc aaatgattat aaccgtcgta gcatcaattt gcaaattgat
    24361 actaacgaac caggtcgtat tatcggctac catggtaaag tcttgaaggc cttgcaactg
    24421 ttggctcaaa attatcttta caactgctat tcaagaacct tctatatcac tattaatgtc
    24481 aatgattatg ttgaacaccg tgcagaagtc ttgcagacct atgcgcaaaa attggcgatt
    24541 cgtgttttag aagaaggacg tagtcatcaa acagatccaa tgtcgaatag tgaacgcaag
    24601 attatccacc gtattatttc acgtatggat ggcgtgacca gttactctga aggtgatgag
    24661 ccaaatcgct atgtcgttgt agatacagaa taagtaaaat cagggttgac ctgatttttt
    24721 gctagctaga ggaggttaaa ctgatgttga ataagataag agactatcta gacttttctg
    24781 gtttgcagta ccgtagtcct gataaagcgg gagcagagcg agagaagatg ctggcattcc
    24841 gccacaaagg tcaagaggca cgaaaggctt ttacagaatt ggctaaagtc tttcaggcaa
    24901 atcatccaga atggcaactc caacagacta gccagtggat gaatcaggcc cagcgtttgc
    24961 gaccacattt ttgggtttat ctacaacgtg aggggaaagt gacagaacct atgatagcct
    25021 tgcgtttgta tggaaatcct tctgattttg gtatttcctt agaggtcagt ttcatcgaac
    25081 gtaagaagga tgagcaaaca ctgggcaagc aggccaaagt tttagacatt ccaaccgtta
    25141 aagggattta ttatctaacc tactctaatg gtcaaagtca acggtgggag gcgaatgaag
    25201 aaaagcgtcg tactttacgc gagaaggtga gaagtcaaga agttcgaaaa gttttagtga
    25261 aggtagatgt tcctatgaca gaaaattcgt ctgaagaaga aatcgtagaa ggcttattga
    25321 agtcttattc taaaattctt ccctattatc tagctacgag aaaataagat aatttgtaaa
    25381 acatcataaa tcatacagtc caagagtgaa cagtccgctg tgtaattctt ggtctttttg
    25441 tttgcgcttt cgcattatat aataaactta caaaaacaat tcaaaaggag aacaattatg
    25501 gaagtcgttt caagtgttct aaattggttt tctagcaata ttttgcagaa tcccgcattt
    25561 ttcgtaggtt tattggtgtt gataggatat gcacttttga aaaaacctgc ccatgacgtt
    25621 ttttcagggt ttgttaaagc aacagtaggg tatatgttgc ttaacgtggg tgctggtggt
    25681 ttggttacaa cctttcgtcc aatcttagca gctcttaact acaaattcca aattggtgca
    25741 gcggttatcg acccttactt tggacttgct gcagcaaaca acaaaattgc agcagagttt
    25801 ccagattttg ttggaactgc aactacagct ctattgattg gtttcggaat aaatatcttg
    25861 ctcgtagctc ttcgaaagat tacgaaggta agaaccctct ttattactgg tcacatcatg
    25921 gtacaacaag ctgcaacagt atctcttatg gttctattct tagtaccaca attgcgcaat
    25981 gcttacggta cagcagcgat tggtatcatc tgtggacttt actgggcagt tagttcaaat
    26041 atgactgttg aggcaactca acgcttgact ggtggtggcg gatttgcgat tggtcaccaa
    26101 cagcaatttg caatctggtt tgtagataaa gtagcaggac gctttggtaa gaaagaagaa
    26161 agtttagaca atcttaaatt acctaagttc ctcttaatct tccacgatac agttgttgca
    26221 tctgctacct tgatgctcgt attcttcggg gccattcttt taatcttggg tccagacatt
    26281 atgtctaata aagaagtcat cacttcagga actctattca atcctgctaa acaagatttc
    26341 tttatgtaca ttatccaaac agcctttacc ttctcagttt acttgttcgt tttgatgcaa
    26401 ggtgtccgaa tgttcgtatc tgagttgaca aacgccttcc aaggtatttc aaacaaattg
    26461 ttgccaggtt cattcccagc ggttgacgtt gcagcttctt atggatttgg ttctccaaat
    26521 gctgtcttgt caggatttac ctttggtttg attggtcaat tgattacaat tgttttgctc
    26581 atcgtcttta aaaatccgat tcttattatt acaggatttg taccagtgtt ctttgacaat
    26641 gcagccattg cggtctacgc tgataaacgc ggcggatgga aagcggctgt tatcctttcc
    26701 tttatatcag gtgtccttca agttgctcta ggagctcttt gtgtggccct tctcgatttg
    26761 gcatcttatg gtggctacca tggaaatatc gactttgaat tcccatggct tggatttgga
    26821 tatatcttca aataccttgg tattgttggt tatgtacttg tgtgtctctt cttgcttgtt
    26881 attcctcaac ttcaatttgc caaagcaaaa gataaagaga aatattacaa cggtgaagtt
    26941 caagaagaag cttagtatct agaaaaggag aaataaaatg gttaaagtat tagcagcgtg
    27001 cggaaatgga atgggttcat caatggttat caagatgaag gttgaaaatg ctctccgtaa
    27061 gcttaatcaa acagatttta cagtcaattc atgcagtgtc ggtgaagcta aaggtttagc
    27121 agtaggatat gacatcgtaa tcgcttctct tcatttgatt caagaattgg aagggcgaac
    27181 taatgggaag ttaattggac ttgataactt gatggatgat aaagaaatca ccgaaaaact
    27241 cagtcaagca ctacagtaaa aggttggagg gggctggaca gaaactgaga gttatcgttt
    27301 ctgtccttct ccctctttaa ataaaggagg cagatatgaa tttaaaacaa gctttaattg
    27361 acaatgactc gatccgacta ggtttagagg ctaacaattg gaaagaagca gtcaaggtag
    27421 cagtagatcc cttaattgaa agtggggcaa ttttgccaga gtattacgat gctatcattg
    27481 aatcgactga agagtatggg ccttactata tcttgatgcc aggtatggct atgccccacg
    27541 ctagacctga agctggtgtg caaagtgatg ccttttcatt gattacctta caaaatcctg
    27601 ttgtattttc agatgggaaa gaggtatctg ttttgttggc actagcagca acaagctcaa
    27661 aaattcacac aagtgtagcc attccacaaa ttattgccct gtttgaatta gaagattcta
    27721 ttgcacgttt acaggcttgc cagactaaag aagatgtctt ggctatgatt gaagaatcta
    27781 aggatagccc ttatctcgaa ggattggatt tggaaagtta gaaagaggaa taaagaaatg
    27841 acaaaaagaa tacctaattt acaagttgca ttagaccatt cagacttgca aggagcgatt
    27901 aaagcagctg tttctgttgg tcaggaagta gatattatcg aagctggaac tgtttgcttg
    27961 cttcaagttg gaagtgaact ggctgaagtc ttgcgtagcc ttttcccaga taagattatt
    28021 gtggcagaca caaaatgtgc tgatgctggt ggaacagttg ctaaaaataa tgcggttcgt
    28081 ggagcagact ggatgacttg tatctgttgt gcaaccatcc ctactatgga agcagctcta
    28141 aaggctatca agactgaacg aggagaacga ggcgaaatcc agatcgagct ttatggcgat
    28201 tggacttttg aacaagctca gctttggcta gatgcaggta tctcacaagc tatttatcac
    28261 caatctcgtg atgctcttct tgctggtgaa acttggggtg aaaaagacct taataaggtt
    28321 aaaaaactca ttgacatggg cttccgtgta tctgtaacag gtggtctaga tgtagatact
    28381 ctcaaactct ttgaaggtgt tgatgtcttt acctttatcg caggtcgtgg aattacagag
    28441 gctgcggatc cagcaggagc agcgcgtgcc ttcaaggatg aaatcaaacg aatttggggg
    28501 taaatcatgg tacgtccaat tggaatttat gaaaaggcaa ccccaacaca ctttacttgg
    28561 ctagaacgtt taaattttgc caaggagtta ggctttgatt ttgtcgagat gtctattgac
    28621 gaacgtgacg agcgtttagc aagacttgac tggagtaagg aagaacgctt ggaagttgtc
    28681 aaagcaatct atgaaactgg tgttcgtatt ccttctatct gtttttcagg ccatcgtcgc
    28741 tacccattgg gttcaaaaga tccagttcta gaggaaaaat ctctagaact catgaaaaaa
    28801 tgtatcgaat tagctcaaga cttgggagtt cgtacgatta gctggttacg atgtttacta
    28861 tgaggaaaag tcaccccaga cacgccaacg ttttatcaaa aatttgagaa aagcctgtga
    28921 ctgggctgaa gaagctcagg tggtacttgc tattgaaatt atggatgatc ctttcatcaa
    28981 tagcatcgaa aaatatttgg ctatagaaaa agagattgac tctcccttcc tctttgtata
    29041 tccagatatt ggtaatgtgt ctgcatggca taatgatatc tatagtgagt tttatcttgg
    29101 tcatcatgcc atcgcagctc tccatctcaa ggatacttat gcagtgacag aaagttcaaa
    29161 gggccagttc cgagatgtac ctttcgggca aggttgtgtc aaatgggaag aagctttcga
    29221 tattttaaag gaaaccaatt ataatggacc tttcctaatc gaaatgtggt ctgaaaattg
    29281 tgaaacagta gaagaaacac gcgcagccat tcaagaggcg caagcttttc tctatccact
    29341 cattaagaaa gcaggtttga tgtaagatga atcaagtaat caatgctatg cgtaaacgag
    29401 tctgtgatgc caatcaatca ttgccaaaac atggacttgt caaatttacc tgggggaatg
    29461 tatctgaagt taatcgcgaa ctcggtgtca ttgttatcaa accatcaggc gtggattatg
    29521 acgaattgac acctgaaaac atggtagtga ctgatctaga tggtaagatc ctagaagggg
    29581 atttaagacc atcttccgac ctcccaactc atgtgcaatt atataaggct tggtcagaaa
    29641 ttggtagtgt ggttcacacc cattcgacag aagctgttgg ttgggctcag gcaggtcgtg
    29701 atattccttt ctacggaaca acccatgcag attatttcta cggttcaatc ccttgcgccc
    29761 gtagtttgac caaggacgaa gtagaagtgg cctatgaaaa agatactggc ctggttatcg
    29821 tagaagagtt tgaacatcgc ggacttaacc cggttgaagt accaggaatt gttgtacgca
    29881 atcacggtcc attcacctgg ggcaaaaatc cagagaatgc tgtttatcac tctgtcgtac
    29941 tagaggaagt atcaaagatg aatcgcttta cagaacaaat caatccaaga gttggacctg
    30001 ctccccagta catactagaa aaacactacc aacgtaaaca tggaccaaat gcttattatg
    30061 gtcaaaagta agaacgatga aggaggagaa aaagataaat ttagctcctc tttttacatt
    30121 tgatttttat tgagagtaaa gttggaattg aagtaatttt aaaagatttt ttagaaatag
    30181 cgcttgatat atatatggta aaataaaaag aattgctgtg atatcaatag atttggggga
    30241 ttttttaata tggtactgga taaggcaagt tgtgatttgc ttcaatattt gatggatcaa
    30301 gaaacgtcca aaacgattat ggcgatttcg aaagatttga aagagtcaag aaggaaaatt
    30361 tattatcaca ttgacaaaat caatgctgct ctggttgacg aggcgcttca catcattagt
    30421 attccacgaa ttggtattca cttaacggaa gagcagagag atgcttgttg taaactatta
    30481 tcggaagtag attcgtacga ttatatcatg agtgcgcatg aacgtatgat gataatgtta
    30541 ctatggatag gtatttctaa agaacgtatt acgattgaaa aattgataga gttaacagag
    30601 gtatctagga atactgttct caatgatttg aatagtattc gttatcaact aactttggaa
    30661 caatatcagg tgatcttgca agtgagcaag tcacagggat accaccttca tgcccaccct
    30721 cttaataaaa ttcagtatct tcaatcgctt ctatatcata tttttatgga agaaaatgcc
    30781 acttttgtat ctattttaga agataagatg aaagagaggt tagatgatga gtgtttgctt
    30841 tctgttgaaa tgaaccaatt ttttaaggaa caggttcctt tagttgaaca agatttaggg
    30901 aagaaaataa accatcatga aataactttt atgttgcagg ttctacctta tttgctgtta
    30961 agctgtcata atgttgaaca gtatcaagaa agacatcagg atatagagaa agaattttct
    31021 ttgataagaa aaagaataga gtatcaggtg tctaagaaat taggagaacg gttgtttcaa
    31081 aagtttgaaa tttctttgtc aggacttgaa gtttctcttg tagctgttct cctcctctcc
    31141 tatcgtaagg atttggatat tcatgcagaa agtgatgatt ttcggcaatt aaaacttgct
    31201 ttagaagaat ttatctggta ttttgaatca caaatccgaa tggagattga gaacaaggat
    31261 gatttgttac gaaatttgat gatccactgt aaagccttgt tatttagaaa gacttacggt
    31321 attttttcta aaaatcctct aacaaaacaa attcgatcca agtatggaga attattttta
    31381 gtcactagaa aatctgcgga aattttagaa ggagcatggt ttattcggct aacagacgat
    31441 gatattgcct atttgacgat tcatattgga ggatttttaa agtatacacc atcgtctcaa
    31501 aaaaatatga aaaaagttta tctcgtttgt gatgaaggtg ttgcggtttc gagacttttg
    31561 ctgaaacaat gcaaacttta ttttccaaat gagcaaattg acactgtatt tacaacagaa
    31621 caatttaaga gtgtggaaga tattgcacaa gttgatgtag tgattactac taatgatgat
    31681 ttggatagca gatttccgat tttaagggtt aatcctatcc ttgaagcaga agatattttg
    31741 aaaatgctag actatcttaa acacaatata tttcgtaata agagcaaaag tttcagtgaa
    31801 aatctttcta gtcttatttc gtcttatatt gtagacagca agttggctag taagttccaa
    31861 gaagaggttc aaacacttat aaataaagaa atagtagttc aagctttttt ggaagatatt
    31921 tgaaggacag tccaatgatg aacacaaacc tgtgtttttc ttggtctttt ttagtgtttt
    31981 gaagggtggt atactaatct caaagataac aattatatcc aaaggaggca acatatgcca
    32041 aacgtcaaag aaattacaag agagtcatgg attttagcca ctttcccaga gtggggaaca
    32101 tggttgaacg aagaaatcga agaagaagtc gtacctgaag gcaactttgc catgtggtgg
    32161 ctaggcaact gtggtacttg gattaagaca ccagctggtg ctaacgttgt catggacctt
    32221 tggtcaaacc gtggaaaatc aaccaaaaaa gtgaaagata tggttcgtgg gcaccaaatg
    32281 gcaaatatgg caggtgttcg taagttgcaa ccaaacttgc gtgttcagcc aatggttatc
    32341 gatccatttg ctatcaacga actagactat tacttagttt cacacttcca cagtgatcat
    32401 atcgacccat acacagctgc agcaattctc aacaatccta agttagagca tgttaagttt
    32461 atcggtcctt accactgtgg acgaatctgg gaaggatggg gtgttccaaa agaacgtatc
    32521 atcgttgtta aaccaggtga cactatcgaa ttaaaagata tgaagattca tgcagtagaa
    32581 tcatttgacc gtacttgctt ggtaactctc ccagtgaacg gtgctgatga gacaggcggt
    32641 gaacttgctg gcttggctgt tacagatgaa gaaatggctc aaaaggctgt taactatatc
    32701 tttgaaacac caggtggaac catctatcat ggtgcagatt ctcacttctc aaactatttt
    32761 gcaaaacatg gtaaagactt taaaattgat gttgctttga ataactatgg tgaaaatccg
    32821 gtaggtatcc aagacaaaat gacatctatc gaccttcttc gtatggcaga aaatctgcgt
    32881 accaaagtca ttatcccagt tcactatgat atctggtcta acttcatggc ttctactaat
    32941 gagattctag aactttggaa aatgcgaaaa gatcgcttgc aatacgattt ccatccattt
    33001 atctgggaag ttggcggtaa gtacacttat cctcaagatc aacacttagt agaataccat
    33061 catccacgtg gttttgatga ttgttttgaa caagactcta acattcaatt taaagctttg
    33121 ctataatata aaaatattct ttggaggtta tccgtatgtt gcatgatacg gataattttc
    33181 atataatagt aaaatagaat gtgtgattca ataatcacct caaatagaaa ggaaattcta
    33241 tgtcaaatct atctgttaat gcaattcgtt ttctaggtat tgacgccatt aataaagcca
    33301 actcaggtca tccaggtgtg gttatgggag cggctccgat ggcttacagc ctctttacaa
    33361 aacaacttca tatcaatcca gctcaaccaa attggattaa ccgcgaccgc tttattcttt
    33421 cagcaggtca tggttcaatg ctcctttatg ctcttcttca cctttctggt tttgaagatg
    33481 tcagcatgga tgagattaag agtttccgtc aatggggttc aaaaacacca ggtcacccag
    33541 aatttggtca tacggcaggg attgatgcta cgacaggtcc tctagggcaa gggatttcaa
    33601 ctgctactgg ttttgcccaa gcagaacgtt tcttggcagc caaatataac cgtgaaggct
    33661 acaatatctt tgaccactat acttacgtta tctgtggaga cggagacttg atggaaggtg
    33721 tctcaagcga ggcagcttca tacgcaggtt tgcaaaaact tgataagttg gttgttcttt
    33781 atgattcaaa tgatatcaac ttggatggtg agacaaagga ttcctttaca gaaagtgttc
    33841 gtgaccgtta caatgcctac ggttggcata ctgccttggt tgaaaatgga acagacttgg
    33901 aagccatcca tgctgctatc gaaacagcaa aagcttcagg caagccatct ttaattgaag
    33961 tgaagacggt tattggatat ggttctccaa acaaacaagg aactaatgct gtacacggcg
    34021 cccctcttgg agcagatgaa accgcatcaa ctcgccaagc cctcggttgg gactacgaac
    34081 catttgaaat tccagaacaa gtatatgctg atttcaaaga acatgttgca gaccgtggcg
    34141 catcagctta tcaagcttgg actaaattag ttgcagatta taaagaagct catccagaac
    34201 tggctgcaga agtagaagcc atcatcgacg gacgtgatcc agtcgaagtg actccagcag
    34261 acttcccagc tttagaaaat ggtttttctc aagcaactcg taattcaagt caagatgcct
    34321 tgaatgttgt ggcagctaaa ttaccaacct tcctaggtgg atcagctgac cttgctcact
    34381 caaacatgac ttatatcaag acggatggac ttcaagacga taccaatcgc ttgaatcgta
    34441 acattcagtt tggtgttcgt gaatttgcaa tgggaacaat cttgaacggg atggcccttc
    34501 atggtggact tcgtgtatac ggtggaactt tcttcgtctt ctctgactat gtgaaggcag
    34561 ctgtccgctt gtcagcctta caaggacttc ctgtgactta tgtctttacc catgattcaa
    34621 tcgcagttgg ggaagatggt ccgactcacg aaccagttga gcatttagca ggtcttcgtg
    34681 ctatgccaaa tctaaatgtt ttccgtccag cagatgcgcg tgaaacgcaa gcagcttggt
    34741 accttgcagt gacaagtgag aaaacaccaa ctgcccttgt cttgacacgt caaaacttga
    34801 ctgttgaaga tggaacagac ttcgacaagg ttgctaaagg tgcttatgtt gtatatgaaa
    34861 atgcagccga ctttgatacc atcttgattg cgacaggttc agaggttaat cttgctgtct
    34921 cagctgctaa agaattggct agtcaaggcg aaaaaatccg cgtagtcagc atgccatcta
    34981 cagatgtctt tgataaacaa gatgcagctt acaaggaaga gattcttcca aatgcagtcc
    35041 gccgtcgtgt tgcagtcgaa atgggtgcaa gtcaaaactg gtacaaatat gttggtctcg
    35101 atggtgccgt tctaggtatt gataccttcg gagcctctgc cccagcacca aaagtattgg
    35161 cagaatatgg ctttactgta gaaaatcttg taaaaattgt tcgaaacttg aaataatcct
    35221 aaaaatcagg gcgtaagctc tggtttttct taccagaaaa gtaaggtaca atcttgtaaa
    35281 agtagctgaa atttgatata gtagtcctat gtaaaagaca aaggagaaaa caatgaatcc
    35341 aaatattact tttttaatca tgcttgtagg tatgatggcc ttgatgttct ttatgcaacg
    35401 ttctcaaaag aaacaagctc aaaagcgtat ggaaagctta aataaactac aaaaaggcta
    35461 tgaagtgatt acaatcggtg gactttatgg aacagtcgat gaagtagata cggagaaggg
    35521 aacaatagtt cttgacgtag atggagttta cttgactttt gaactagctg ctatcaagac
    35581 agtattaccg ctgaaagaaa cagcttcact agaaggcgca attgaaaaat aagacgggat
    35641 cacgaactcc cgtttttcta taaaagaaag gaaatgggat gaaaaaatta gtctttgtct
    35701 gtctgggaaa tatttgccgt agccctatgg ccgagtttgt tatgaaatca atgacagata
    35761 actacgaaat ccaaagtcga gcaacttcct cttgggaaca tggcaatccg attcataagg
    35821 ggactcaggg aatttttcaa gagtatgaga ttccttatga caagaacaag acatcgcttc
    35881 agattagtaa ggaagatttt gaagcctttg attatattat cggaatggac gcttcaaata
    35941 tttctgactt atgtcagatg tgtccagtag actgtcaaga taagatttac tcattttcat
    36001 ctgaaagtgt tccagaccct tggtatacag gagattttga agaaacctat cgacgtgttc
    36061 aagagggctg tcaagcttgg ttagaacgtt tagaaaagga gagttaaggt ggaaaatctt
    36121 acgaattttt acgaaaagta tcgtgtctat ctgactcgtc cacgtttaga gcttttggca
    36181 gtagttacca ttgttttttg tgctgtactc gtcttttttc taaatattcc aggaaaaggt
    36241 gtcttaaaac tcgataatgg aacgattgtt tatgatggca gtcttgtccg tggtaaaatg
    36301 aatggtcaag gtaccattac cttccaaaat ggagaccaat atacaggtgg cttcaacaat
    36361 ggagccttca acggaaaagg tacctttcaa tctaaagaag gctggaccta cgaaggtgat
    36421 tttgtaaatg gtcaggctga aggaaaaggg aaactaacaa cagaacaaga agtcgtttat
    36481 gaaggaactt ttaaacaagg cgtttttcaa caaaaataaa gcctccttat caaaggaggt
    36541 attattagaa ttacaaggta agcgcttacc tgtaaatctc tttctttcca aatccctctt
    36601 ccaagcaagt ttgtgaaata aaaaatattt gaaataaatt tcacaaactt caaagataaa
    36661 acctgataag aaaagaaaat gagaaaagtt tcacaagagt ttaaaaattc tttgtgaaat
    36721 gtttatgaaa ctgtttacaa agttgaaata atacgttata ataaacttgt gaaaaaatta
    36781 acaaaggata tcgatccttg aaagctgtgg aggaaaatat ggctgataaa aaaactgtga
    36841 caccagagga aaagaaactc gttgctgaaa aacacgtaga tgagttggtt caaaaagctc
    36901 tagttgccct tgaagaaatg cgtaaattgg atcaagagca agttgactac atcgttgcca
    36961 aagcatcagt agcagctttg gatgcccacg gagaattggc tttacatgcc tttgaagaaa
    37021 caggacgtgg tgtatttgaa gataaagcaa ctaagaactt gtttgcctgt gaacacgtag
    37081 taaacaacat gcgtcacact aagacagttg gcgttatcga agaagacgat gtaacaggat
    37141 tgactcttat tgctgaacca gttggtgttg tttgtggtat tactccaaca acaaacccaa
    37201 catcaacagc aatcttcaaa tcattgattt cattgaagac acgtaaccca atcgtctttg
    37261 ccttccatcc atcagcacaa gaatcatctg ctcatgcagc tcgtatcgtc cgcgatgcag
    37321 ctatcgcagc tggtgctcct gaaaactgtg tgcaatggat tactcaacca tctatggaag
    37381 caacaagtgc ccttatgaac cacgaaggtg ttgcaacaat ccttgcaaca ggtggtaatg
    37441 ccatggttaa agccgcatac tcatgtggta aaccagctct tggggtaggt gccggaaacg
    37501 ttccagctta tgttgaaaaa tcagcaaaca ttcgtcaagc agcacacgat atcgtcatgt
    37561 ctaaatcatt tgataacggt atggtctgtg catctgaaca agcagttatc attgataaag
    37621 aaatttacga tgaatttgta gcagagttca aatcttacca cacttacttt gtaaacaaaa
    37681 aagaaaaagc tcttcttgaa gagttctgct tcggcgtcaa agcaaacagc aaaaactgtg
    37741 ctggtgcaaa attgaacgct gacatcgttg gtaaaccagc aacttggatt gcagaacaag
    37801 caggatttac agttccagaa ggaacaaaca ttcttgctgc agaatgtaaa gaagttggcg
    37861 aaaatgagcc attgactcgt gaaaaattgt caccagttat tgcagttttg aaatctgaaa
    37921 gccgtgaaga tggtattact aaggctcgtc aaatggttga atttaacggt cttggacact
    37981 cagcagctat ccacacagct gacgaagaat tgactaaaga atttggtaaa gctgttaaag
    38041 ctattcgtgt tatctgtaac tcaccttcta cttttggtgg tatcggggac gtttacaatg
    38101 ccttcttgcc atcattgaca cttggatgtg gttcttacgg acgcaactca gttggggata
    38161 acgttagtgc cattaacctc ttgaatatca aaaaagtcgg aagacggaga aataacatgc
    38221 aatggatgaa acttccttca aaaacatact ttgaacgtga ttcaattcaa taccttcaaa
    38281 aatgtcgtga cgttgaacgt gtcatgatcg ttactgacca tgccatggta gagcttggtt
    38341 tccttgatcg tatcatcgaa caactggacc ttcgtcgcaa taaggttgtt taccaaatct
    38401 ttgcggatgt agaaccggat ccagatatca caactgtaaa ccgtggtact gagattatgc
    38461 gtgccttcaa accagatacc atcatcgcac tcggtggtgg gtctccaatg gatgctgcca
    38521 aagtaatgtg gctcttctac gagcaaccag aagtggactt ccgtgacctt gtccaaaaat
    38581 tcatggatat ccgtaaacgt gccttcaagt tcccattgct tggtaagaag actaaattca
    38641 tcgcgattcc aactacatct ggtacaggat ctgaagtaac accatttgcc gttatctctg
    38701 ataaagcaaa caaccgtaaa tacccaatcg ctgactactc attgatacca actgtggcaa
    38761 tcgtagatcc tgctttggta ttgacagttc caggatttgt tgctgctgat actggtatgg
    38821 acgtattgac tcacgcgaca gaagcatacg tatcacaaat ggctagtgac tacactgatg
    38881 gtttagcact tcaagccatt aaattggtct ttgaaaatct cgaaagctca gttaagaatg
    38941 cagacttcca ctcacgtgag aaaatgcata acgcttcaac aatcgctggt atggcctttg
    39001 ccaatgcctt cctaggtatt tctcactcaa tggcccataa gattggtgcg caattccaca
    39061 caatccacgg tcgtacaaat gctatcttgc ttccatacgt tatccgttac aacggtacac
    39121 gtccagctaa gacagcaaca tggcctaagt acaactacta ccgtgcagat gaaaaatacc
    39181 aagatatcgc acgcatgctt ggacttccag cttctactcc agaagaaggg gttgaatctt
    39241 acgcaaaagc tgtctacgaa ctcggtgaac gtattgggat ccaaatgaat tttagagacc
    39301 aaggaattga cgaaaaagaa tggaaagaac attctcgtga attagccttc ctggcttatg
    39361 aagaccaatg ttcaccagct aacccacgtc ttccaatggt agaccatatg caagaaatca
    39421 tcgaagatgc atactatggc tacaaagaaa gaccaggacg ccgtaaataa ttgtttatca
    39481 gtctagaagc aagacaaaaa ctcaatttga gggaaagatc cagtaatttt tctatgataa
    39541 aaggcatcct atcaaggttt ttgaatacct gataggatgc ctttttatga tgttgaggcc
    39601 tttttgccct ttttgaaaaa ctagaataga aacaaaatat atagcagatt gaaactagaa
    39661 tagtacacat ctgcttctaa aacatttata gaaattaatt ttagtttcct gatagagttg
    39721 tttacatctt atttcaattc actatagttt aatttaagag tagtatttac taaggcccaa
    39781 ttaaaatcaa agagcaaact agaaaacgag tgccattcag ctcaaaacac tgatttgaga
    39841 ttgcagataa gactagcccc ctcattaaca gatttacgat aaaacgatga caaggtgtgt
    39901 tactttttga tttctaaaga gtataatgat agatctctat aaaataagtg cgaaggaaat
    39961 gagcttttat agtcctttcg ttttaaaata ctatctcaga tattcttata tcgacaagaa
    40021 gtttttgagt cattccctca tcatacatat taaataaata gtggctcatt caatttttca
    40081 ctagaataat aagctagtat agtaaactga aataagatat aaacaaataa attggagctt
    40141 aacatctatt tccagcaatt ttttagaaac tgcagtggac tattctagat tcaacatatt
    40201 ataaaaacta gagtaaaaga aaaggattgg atcttgtgta atgcaggatc caatcctttc
    40261 aatcattttg tccaactttt ggaggttcct acaatgtagt cgtcattaat aaagacagat
    40321 gggaacgaca gtgttcctat ttattttgat agagatcgat gaattcttta gatagcaact
    40381 gaataatctc tgttgaagcc atttggtctt ctgcatgcat aaatagcaag gagaatccta
    40441 ttttttctcc agtagcttct ttttgtatga gattggagtg aatcttgtgc gcttctacta
    40501 aggagtcttc cgcttcttca actttaattt tcgcttcttt taaatttcct gccttagcta
    40561 gttggatggc ttcaataaag gatgatttgg ctgctccact attggcaatg agctgaaaac
    40621 agatatattc catttcttct gtcatcttat ttctcctatc cattcaagtg cttgttccag
    40681 aacttttgct ccattcatca ttccgtaatc ccgcatatca atggtatcta cagggatatt
    40741 tcctgcaatt tctttcacag caagtaactc ataacgaatt tgtggcccaa ttagaatgac
    40801 atctgcttca tggatatttt ttttagcttc tgtcattgat tttgcttgga tagaaatttc
    40861 aatcccacgt tcagtcgcac tttgttgcat ttttttaaca agcatacttg tcgacattcc
    40921 cgcattacat actaataaaa tttgtttcat aatcttaacc ttccatttct tgttcaacaa
    40981 ctttgtcatt aactttgata aatggaatgt atagaagaac tccaagtgca aagatgatga
    41041 attgaactag aactgctctc acgtcccctg ctgttgctaa ccatgcattt aagaatactg
    41101 gtgtagtcca aggaacttgt ataaatgcag gactcatgaa tcctgtaact gttgctaagt
    41161 agctgattaa aataccaagt actggaactg tgataaatgg aatagctaat gaaatgttat
    41221 aaacgattgg gtaaccgaat aatactggtt cattgatatt gaagatacca ggtccaaaag
    41281 ataatttagc cacgttttta gaaacagcat tgcgacttac taagaatgtt gctattaata
    41341 aacataatgt agatccacta ccacccatta aagcgaatgt ttgtatttgt gataagttga
    41401 tgatgtgtgg aatggcttgt ccattatttg ctgcagtgat gttttcagta atgttaatta
    41461 atagtaatgg ttctaggatg gcactgtaaa taactgcttg gtgaatacca aatagccata
    41521 acatatttcc taaagagtaa ataataatga ccccgattaa gcttgtacca atatgacgaa
    41581 ttggttcttg aataaagatt gtaatgattg agattaagtt cattccagtt atattgaata
    41641 ataatgctga aacaacccca aataaggaga tgacggtcat gactggaagt aatacgctaa
    41701 atgatctact aacagctggt ggaatatttt caccaaggtt catttgtaaa gctttaacgt
    41761 ttgataattc aatgaataat tctgttgcaa taatcgctac gataaccccg gcgaacattg
    41821 cgcctgtacc tgtgttgttg aatgaaagaa cacctgaaat gtttaccgca tcttttgctc
    41881 cgtcaggaac tacagaaact gtatttggca tcatcacaat taaagaaact aatgatagca
    41941 ttgatgctgc taacgggttt tcgaaatctc tgtttttagc taagaaataa ccaaccatta
    42001 cagcaataat catacctgaa atacttaaag taccgtttgc aattgttatt ccccaatatt
    42061 ggaatcttgt taatgtatcc ccttggaaaa tccacttaaa taccgtgttg ttcaaaagaa
    42121 cgattaaacc tgccaaaata tataatggca ttactgttac gaatgcatct cttagggttt
    42181 ttaaatgaat ttggttccct agtttaccag caaaggtggc aaattgatct ataaattttg
    42241 agtttttcat ctgaatatct cctctcttta ctcctcaatt tctacttcaa aaccgttatt
    42301 gtcacttact ttgcgatacc atcttcctga tctcttgatg gttctctttt gcgtttctaa
    42361 atcaacggag ataaatccgt aacgattctt atatgcatta ttccaagacc agcaatcaaa
    42421 tgcggtccaa gcgtggtatc caaaacagtg acttccctct tcaatggctt tatgtagcca
    42481 tcttaaatgt tcttcataaa attcaatacg atacacgtca tcgataactc cattttcacc
    42541 gataaaccgt gcttcgtttt caacacccat tccgttttca ctgataaacc atggaatatt
    42601 accatattct ttcttcacaa tcatagcaat atcataaatg gctttcggaa aaatttccca
    42661 accacgatat ggattcatgc gacgctccgg ccattcatac tctttgaagt attggtctgg
    42721 catccagggc gtctgatatt cctcaggatt tgcttgtgct tgaacacgtt ttggatggta
    42781 gtagtttact ccaagaaaat caaccgtatt tgatttcatc agttgaagct ctttttcggt
    42841 atgactccat aacacgccat ctctctctag ctgttttacc aatctttctg ggaaagttcc
    42901 tttaacagct ggattcaaga agactttgtt aaagaagtca tctgtaaatc gacttgcttc
    42961 taagtcttct ggagaattac ttcttggata agcaggtgtc aagtttaaaa taatcccaat
    43021 ctttccatca agtcctaatg agcgatatag ttgaatcact tttgcactag caaggtttag
    43081 attatagatg acttgtacgg cctcttttcc ctttcctttt agatttggat aatggaaagc
    43141 atataagtat cctgcttctg gaatgaccat tggctcattg aaagttgtcc agtaatgaac
    43201 cttatctcca aagcatgtga aagcagtctt ggcaaacttc acgaataact ccactacatg
    43261 tttgctttcc caaccaccgt atttttgaag aagttccact ggtaaatcaa aatgatgtaa
    43321 attcatcaca agatccatct ggttcttttt agcttcttca atgatggcat tgtagaaagc
    43381 aatacctttt ggatcaggct cacctgtctc taaattcttg atgagtcgac tccattggat
    43441 ggaagtgcgg aaagaattaa ctccaatttc cttcatcaag tggaaatctt cggtgtaagt
    43501 atgaaaaaag ttactggcta caagaggtcc gacattatcg aaaaaatctt ctggatgcgt
    43561 tttgaaccag tagtccatca cattttcatg tacttttcca tattgacctt ctgtctgagg
    43621 tccgctagaa gcagctcccc accaaaacag attaggaaat actaactttt ttttcatgct
    43681 caacctcctt tctattattc tatacataaa gtatagcata attttaaaat ttgtctagac
    43741 atttttaaaa attgttgata catatcttgt gtttgcctca tttcttgaac tttgttatac
    43801 tactattaga atattataga gagaaccaga ttaaatgagt acaaaatatt tatttattta
    43861 caatgagatt cgtgaaaaga ttctttgtaa taaatatacc atgaacgaac aattgcctga
    43921 tgaaatgaca ttagctaaac agtttgcctg tagtcgaatg acgatcaaaa aagctttaga
    43981 cttgttagtt tctgagggct taatttttag aaaacgtggg cagggaacct ttgttctctc
    44041 tcgtggcagc tcaaaaagaa aattaatcgt tccagaaaga gatatccggg gattgacaaa
    44101 aatatctgaa gatgctcatt ctacaattga ctcgaggatt attcacttca aattagaatt
    44161 tgcaaatgaa tttttagcag aaaaactaca ggtcgctttg cagagtccag tttataatat
    44221 ttaccgcctg cgtattattg acggtaaacc ttatgttctg gaacaaactt atatgagtac
    44281 cgatgttatt ccaggtatta ctgaagatat tttacaaaaa tcgatttaca attacattga
    44341 aggaaagtta ggattgcata ttgccagtgc tacaaaaatc ttgcgagctt cttctagttc
    44401 agaaaatgag caacattact tgcagctcct tccaacggaa ccggtatttg aagtagaaca
    44461 agtggcttat ttggataacg gaactccgtt tgagtactcg attagtcgtc atcgctatga
    44521 tttatttgaa tttaattctt ttgcattacg acattcctcc taggagaaaa tgtgaaaatg
    44581 aagccaatct tttacagact ctagtttaag aaaaatttaa aacagggcaa gaaggtccca
    44641 tctatgctta aatggtttct cttttctaaa taagatggct ttaaaagagt gatcgttgta
    44701 tccatcatgt tgaaaaatat cttcgtatag cttatagagt aggtactgaa attgttcacc
    44761 tgatctactt cttatagtta tttagtttta aatagtgttt caaacattct tacactgacg
    44821 agaagttttt gagtcttttc ttgtaacaca tatagtatac tgtggttaga atagtagact
    44881 gtgacttcta acaaattgct agaaatgaat ttcaatctcc caatttattt acttatatat
    44941 tattttaata tattaaacaa attctgaatc ataatcattt aaaaaaattt tattttttta
    45001 tttttcatta cgaataatat agatgaaggg gaaagagtat gaaaacagaa ctgtttcttt
    45061 tgctattagt tcaaaaggag aaaaaatgaa agtagaaaat atttcgtata gggtggatca
    45121 tcgtaaattg tttgataata tttcttttga tacttcgagt tcagacgtga cattaattac
    45181 tggtaaaaat ggtacaggaa agtcaacttt actatagtag attgaaacta gaatagtaca
    45241 cctctacttc taaaatattg ttagaaatcg atttgactgt cctgatctat ttgtcctggt
    45301 cttattttat tttactacat ctcaaattga gtatgacgaa gtgcgctccc atgtcctggg
    45361 aacgcacttt cttcatattt ttcatattct tgaatccatc gataaagact attgggatga
    45421 atttttaaag ttgaactaat catttttaca ggatgagatt tacagcagag agtttgaagg
    45481 ctttatcaaa ggtttttctt ggcataatga cttttcctcg tttccactta attttgtgtc
    45541 tactttatta taccaagtcc acccttaagt tagataataa atctaactta aggaagctag
    45601 aaggatgaga atccaggtgg tcaagagtcc caaacttaag ctgatgggga cacccagaat
    45661 aatttgcttt ttgaaggcaa ggccacgttc ctctatattg ggaagtgaga gttgaatgag
    45721 agaaccagct gatgaaaagg gtgagatatt agtagataga gcgccaataa cggtggctgt
    45781 tgtgagtaag tgaatatcaa tctgaggatt ttgagcactg atgatagcaa tgatgggaaa
    45841 gagggctgga gctacaacgg atagggtgga actaaagagt gacatcactc cggctatcac
    45901 acaaaagaac agaggtaacc agaaatgagg aatggttgtt gtcatgaggt gccctatcag
    45961 tgtgactaaa cctgacttga ccgctagaga cattagtaag ctcatgccgc agagcatgat
    46021 aattgtagcc cagggaacct tagctaaaat ggcttcttgc ttccctaatt tgagccttaa
    46081 ggcgaggcag accatgagta ttgagacaaa gccaatatca aatgtttttt gataagtagc
    46141 tatccaggcg atgtttggga aaatgagatg caacaaggga aaaagccaaa ccaaaaccat
    46201 gctgctgatc atgagcaagg tggtttgtct ttgaaccttg ctgaggagtg gtggttggtc
    46261 aatagtcaag gatgagtttg ttcttccctt actatagtga ctgtaacagg ataataaaag
    46321 caagacgatg agtgggtaga taatgctgac gataaagata tgattgccaa gtgaaaaagc
    46381 ttgctcttcc catcccattt gcttaaacag gccttgaaag acaatgcctg agctactggt
    46441 tatcaaatta gcccctcctg aagctcccca attgacggct tgagctccaa tcaaagggtg
    46501 tttgtccgct ttttgacaga gggtaatcgc tagaggacag caaacggcca tagtagtgaa
    46561 aaatccagca cctaaagcag acaaaagggt tgccatcagg tataaaatca tgtagagggc
    46621 gttagggtgg gtgcgtgtgc ggtagagaat gtgttgagcc aaaacatcaa gagtaccgtt
    46681 agttgttgca acgttataaa agagagagac gctaaaaatg gtaaaaaaga gtgaggttgg
    46741 ccaaaaatga agaagttctt tggggcttaa tcccatgaga gtggttgcga tgaggtaaga
    46801 aaaagcaata gccagcaggc caatattgat tttggtgcgg taaccaattc caatggctag
    46861 agcaatggcg ctaatcatta ttaaatgaat cattgaattg tcctttcagt tagaatatgg
    46921 aaataggttg gcaattttgg cgctcaaaag accacctgtt tcctattggt acttgactat
    46981 tatacacaaa aaaaatacaa ttgtcttgac aattgtattg acacttgtta gaattaaaaa
    47041 tgaggtattc aggcttgtga tttcctatgg aagttaatag tgattgcctc taatgcttac
    47101 aagtgatatt aaaaatagag gacctagtga tgtcaatcat ttcaactgat ttaacccctt
    47161 ttcaaataga tgatacattg aaagcagcct tgcgagaaga tgttcattcc gaagattaca
    47221 gtaccaatgc catttttgat catcatggcc aagccaaggt gtcgcttttt gccaaggaag
    47281 ctggtgtttt agcggggcta accgtttttc aaagggtttt taccctattt gatgccgagg
    47341 tgaccttcca gaatcctcat caatttaagg atggggatcg tttgactagt ggcgatttgg
    47401 ttttagaaat cataggctcg gtgagaagtc tcttaacatg tgaacgcgtt gccttgaatt
    47461 ttttacaaca tttatcaggg attgcttcga tgacagctgc ttatgtagaa gccttaggcg
    47521 atgattgcat taaggtattt gatactcgaa aaactactcc taatttacgt ctttttgaga
    47581 aatatgccgt gagagttggc ggtggctata atcatcgctt taatttatca gatgctatcc
    47641 tgctaaaaga caatcacatt gcggcagtag gtagtgttca aaaggcaatt gctcaagcgc
    47701 gtgcctatgc cccttttgtg aaaatggtcg aggtggaagt ggaaagcctt gctgctgccg
    47761 aagaagctgc ggcggcgggt gctgatatta tcatgttgga taatatgtca ttggaacaga
    47821 ttgaacaggc cattacccta attgcaggac gttctcggat tgaatgttct ggaaatattg
    47881 atatgaccac tattagccgt tttcgtggtt tagcgattga ttacgtctcc agtggtagtt
    47941 taacccatag tgctaagagt cttgattttt ccatgaaggg tttaacctac cttgatgtct
    48001 aagttgtaaa ataaactaac tttttaaagg atgtctttcc tctagaacga gttttatgtc
    48061 agatagttta aacgcctctt caaatatagt aaaatgaacc aaaaatagta cacaatgtgg
    48121 tataatcttc ttatgg
//
LOCUS       DAVHTH010000010        48054 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.010, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000010 DAVHTH010000000
VERSION     DAVHTH010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 48054)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48054)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48054
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.010"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            complement(26..199)
                     /locus_tag="VVR63_000580"
     CDS             complement(26..199)
                     /locus_tag="VVR63_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001022221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteinase"
                     /protein_id="HEU6128624.1"
                     /translation="MNIKKRVLSAGLTFASALLLAACGQSGSDTKTYSSTFSGNPTTF
                     NYLLDYYADNIVN"
     gene            complement(358..1965)
                     /locus_tag="VVR63_000581"
     CDS             complement(358..1965)
                     /locus_tag="VVR63_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HEU6128625.1"
                     /translation="MQEKWWHNAVVYQVYPKSFMDSNGDGVGDLPGITSKLDYLAKLG
                     ITAIWLSPVYDSPMDDNGYDIADYQAIAAIFGTMEDMDQLIAEAKKRDIRIIMDLVVN
                     HTSDEHAWFVEACENTDSPERDYYIWRDEPNDLDSIFSGSAWEYDEKSGQYYLHFFSK
                     KQPDLNWENEKLRQKIYEMMNFWIDKGIGGFRMDVIDMIGKIPDEKVVNNGPMLHPYL
                     KEMNQATFGDKDLLTVGETWGATPEIAKLYSDPKGQELSMVFQFEHIGLQYQEGQPKW
                     HYQKELNIAKLKEIFNKWQTELGVEDGWNSLFWNNHDLPRIVSIWGNDQEYREKSAKA
                     FAILLHLMRGTPYIYQGEEIGMTNYPFETLDQVEDIESLNYAHEALEKGVPIEEIMDS
                     IRVIGRDNARTPMQWDESKNAGFSTGQPWLAVNPNYEMINVQEALANPDSIFYTYQKL
                     VQIRKENSWLIRADFELLDTADKVFAYIRKDGDRRFLVVANLSNEEQDLTVEGKVKSV
                     LIENTLAQEVFEKQILVPWDAFCVELL"
     gene            2118..3602
                     /locus_tag="VVR63_000582"
     CDS             2118..3602
                     /locus_tag="VVR63_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HEU6128626.1"
                     /translation="MKKQAFSSEQYLNLQRDHILERINQFDGKLYLEFGGKMLEDFHA
                     ARVLPGYEPDNKIKLLQELKEQVEVVIAINASNIEHSKARGDLGISYDQEVLRLIDKF
                     NELGIFVGSVVITQYAGQPAADAFRNQLEKNGIDSYLHYPIKGYPTDMDHIISPEGMG
                     KNDYIKTSRNLIVVTAPGPGSGKLATCMSNMYHDQINGIKSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLQTYGETTVNYNRDIEIFPVLKRMLERILGKSPYA
                     SPTDMGVNMVGFAITDDEAAVEASKQEIIRRYYQTVLDFKAEKVSEAAVKKIELLMND
                     LGITPADRKVAVVARQKAEETGGPALAFELPNGEIVTGKNSELFGPTAAALINAIKKS
                     ADIAKEVKLIEPEVVKPIQGLKIDHLGSRNPRLHSNEILIALAITATENPDAARAMEE
                     LGNLKGSEAHSTIILTDEDKNVLRKLGINVTFDPYYQYDRLYRK"
     gene            3697..4179
                     /locus_tag="VVR63_000583"
     CDS             3697..4179
                     /locus_tag="VVR63_000583"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HEU6128627.1"
                     /translation="MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLV
                     QPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAKIAAV
                     IKDSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWARLILEQGISDDAFERHVI
                     "
     gene            complement(4246..4581)
                     /locus_tag="VVR63_000584"
                     /pseudo
     CDS             complement(4246..4581)
                     /locus_tag="VVR63_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
     gene            complement(5032..7137)
                     /locus_tag="VVR63_000585"
     CDS             complement(5032..7137)
                     /locus_tag="VVR63_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEU6128628.1"
                     /translation="MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTPEEF
                     AHYRATGQLPGNAETDVQMPQQASGMKQDGVLAKLGRNLTAEAREGKLDPVIGRNKEI
                     QETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
                     EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKP
                     ALSRGELTVIGATTQDEYRNTILKNAALARRFNEVKVNAPSAENTFKILQGIRDLYQQ
                     HHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAAQHPVTDVHAVEREI
                     ETEKDKQEKAVEAEDFEAALNYKTRIAELERKIENHTEDMKVTASVNDVAESVERMTG
                     IPVSQMGASDIERLKDMAHRLQNKVIGQDKAVEAVARAIRRNRAGFDEGNRPIGSFLF
                     VGSTGVGKTELAKQLALDMFGTQDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNSN
                     TLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVIIATS
                     NAGFGYEANLTEDADKPELMDRLKPFFRPEFLNRFNAVIEFSQLTKEDLSKIVDLMLA
                     EVNQTLAKKDIDLVVSQAAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLD
                     AKHLEADMKDGVLVIREKA"
     gene            complement(7746..8726)
                     /locus_tag="VVR63_000586"
     CDS             complement(7746..8726)
                     /locus_tag="VVR63_000586"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HEU6128629.1"
                     /translation="MFISISAGVVTFLITLVGIPAFIQFYRKAQITGQQMHEDVKQHQ
                     AKAGTPTMGGLVFLIAAVVVSFLLALFSKQLTNNVGMILFILVLYGLVGFLDDFLKVF
                     RKINEGLNPKQKLALQLLGGVIFYLFYERGGDMLSVFSYQVHLGIFYIIFALFWLVGF
                     SNAVNLTDGIDGLASISVVISLSAYGVIAYVQGQMDILLVILAMIGGLLGFFVFNHKP
                     AKVFMGDVGSLALGGMLAAISMALHQEWTLLIIGIVYVFETTSVMMQVSYFKLTGGKR
                     IFRMTPVHHHFELGGLSGKGNPWSEWKVDFFFWGVGLLASLLTLAILYLM"
     gene            complement(8728..10980)
                     /locus_tag="VVR63_000587"
     CDS             complement(8728..10980)
                     /locus_tag="VVR63_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PASTA domain-containing protein"
                     /protein_id="HEU6128630.1"
                     /translation="MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNF
                     AVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDE
                     NYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGSKGNGITY
                     ANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSG
                     MESSLNSILAGTDGIITYEKDRVGNIVPGTELVSQQTVDGKDVYTTLSSPLQSFMETQ
                     MDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEGITEDFVWRDILYQSNYE
                     PGSAMKVMTLASSIDNNTFPSGEYFNSSEFKIADATTRDWDVNDGLTTGGMMTFLQGF
                     AHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAGQLPADNIVSIAQSSF
                     GQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQKEIVGNPVSKEAA
                     STTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIADEKNGGYLVGST
                     NYIFSVVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMKESLNLQSPA
                     KNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVEEGTNLAP
                     NQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGSVVQKQDVRTNTAIKN
                     IKKIKLTLGD"
     gene            complement(10984..11301)
                     /gene="ftsL"
                     /locus_tag="VVR63_000588"
     CDS             complement(10984..11301)
                     /gene="ftsL"
                     /locus_tag="VVR63_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HEU6128631.1"
                     /translation="MAEKMEKTGQILQMQLKRFSRVEKAFYFSIAVTTLIVAISIIFM
                     QTKLLQVQNDLTKINAQIEEKKTELDDAKQEVNELLRAERLKEIANSHDLQLNNENIR
                     IAE"
     gene            complement(11313..12263)
                     /gene="rsmH"
                     /locus_tag="VVR63_000589"
     CDS             complement(11313..12263)
                     /gene="rsmH"
                     /locus_tag="VVR63_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HEU6128632.1"
                     /translation="MTKEFHHVTVLLHETIDMLDVKPDGIYVDATLGGAGHSEYLLSK
                     LSEKGHLYAFDQDQNAIDNAQKRLAPYIEKGMVTFIKDNFRHLQARLRETGVQEIDGI
                     CYDLGVSSPQLDQRERGFSYKKDAPLDMRMNQDASLTAYEVVNNYDYHDLVRIFFKYG
                     EDKFSKQIARKIEQAREVKPIETTTELAEIIKLVKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADESIQQAMDMLALDGRISVITFHSLEDRLTKQLFKEASTVEVPKGLPFIPD
                     DLKPKMELVSRKPILPSAEELEANNRSHSAKLRVVRKIHK"
     gene            12429..12623
                     /locus_tag="VVR63_000590"
     CDS             12429..12623
                     /locus_tag="VVR63_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU6128633.1"
                     /translation="MNRVKEFRKELGISQLELAKDIGVSRQTINMIENDKYNPTLELC
                     LNLARSLQTDLNSLFWKEDF"
     gene            12639..12881
                     /locus_tag="VVR63_000591"
     CDS             12639..12881
                     /locus_tag="VVR63_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6128634.1"
                     /translation="MKKEKKQLRYPGLKAGSIYGTVIFFIIPLIDTLTSENPNFISSL
                     LNTKHIFKTILGAFFFGVMIHIVDSLRIARAKKDQD"
     gene            12892..13227
                     /locus_tag="VVR63_000592"
     CDS             12892..13227
                     /locus_tag="VVR63_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6128635.1"
                     /translation="MKSLARLLIIHVFISIFLFFALISGAVSHTVLLLLLLFLPALNK
                     GLEKIQSKRIPVLNAALFFLLISFPQLLTNPVQWKFSIFLVVTIISSLAYFYNFYQVV
                     KEVDQKQLI"
     gene            complement(13337..14338)
                     /locus_tag="VVR63_000593"
     CDS             complement(13337..14338)
                     /locus_tag="VVR63_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU6128636.1"
                     /translation="MEKKLTIKDIAEMAQTSKTTVSFYLNGKYEKMSQETREKIEKVI
                     HETNYKPSIVARSLNSKRTKLIGVLIGDITNSFSNQIVKGIEDIASQNGYQVMIGNSN
                     YSQESEDRYIESMLLLGVDGFIIQPTSNFRKYSRIIDEKKKKMVFFDSQLYEHRTSWV
                     KTNNYDAVYDMTQSCIEKGYEHFLLITADTSRLSTRIERASGFVDALTDANMRHASLT
                     IEDKHTNLEQIKEFLQKEIDPDEKTLVFIPNCWALPLVFTVIKELNYNLPQVGLIGFD
                     NTEWTCFSSPSVSTLVQPSFEEGQQATKILIDQIEGRNQEERQQVLDCSVNWKESTF"
     gene            complement(14398..16299)
                     /locus_tag="VVR63_000594"
     CDS             complement(14398..16299)
                     /locus_tag="VVR63_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate lyase family protein"
                     /protein_id="HEU6128637.1"
                     /translation="MKEERRQFFERVDGNQCRDYILSHCSKDYEKVKSSLERLIDNRF
                     MFDSPWDMEPCSKIHQIQPMVWDQVFEDDPEWSYMLNRQEYLLQFMIGYLVEGDKGYI
                     QKCKFFLFDWIEQVREFSPQSLMTRTLDTGIRSFTWLKLLLLLLKFDLLEEKELEKIL
                     VSLEKQIDFMKSHYRAKYTLSNWGILQTIPMLAIYYFFSDKMDLEEAYHFASEELKQQ
                     IETQILGDGSQFEQSILYHVEVYKALLDLCLLLPDLQDSYRELLEKMATYIQMMTGLD
                     GRTLAFGDSDSTETTEILSLSAVVLNKEDLLNGLDVKVDLLSLLFLGREKVKRLQEFE
                     RRAWQPKSMIFEDSGHVCIKDEHRYLFFKNGPLGSAHSHSDENSFCLQYQGQPIFIDA
                     GRYSYREIYERYLLKSAWSHSTCIVDGKAPERITGSWEYEYYPHSLFCHHKEREGVHY
                     IEGAYWSAEPDLPYLHKRKILMLVEDVWLLVDDIRCQGQHEALTQFILDKDVTYQDGK
                     INQLRLWSEVDFDLEDTIISPKYNELERSSKLTKRQFFENQMLDYTIIAHESFEIIRH
                     SVYQTDDREVENALAFEVKNDETDKLILLLSEDIGVGEKLCLVDGTKMRGKCLVYDKI
                     NERMIRLQC"
     gene            complement(16321..16614)
                     /locus_tag="VVR63_000595"
     CDS             complement(16321..16614)
                     /locus_tag="VVR63_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000381741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEU6128638.1"
                     /translation="MDTTLFYGIVIVLAVSPLLLSSFHSIRQQKLLRKQMEQRQEYLA
                     SLTSGDEVLLLSGIHGKIISIQDDLVSLQIAKGVVIYVEKESVMGKTKELLFK"
     gene            complement(16614..17432)
                     /locus_tag="VVR63_000596"
     CDS             complement(16614..17432)
                     /locus_tag="VVR63_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEU6128639.1"
                     /translation="MTGSNKLTKRDYLKTSLRAFFCQNGFNYSNYQGLGYANVMYPAL
                     KKHYGEDQEGFYQALEENCEFYNTNPHFLPFITSLHLVMLENGRPAKETRSIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASFAQEGLVVGPILFFLAMNTILTAIKLSTGLYGYK
                     LGTTVIDKLSEQMATISRIANIIGVTVIAGLAATSVKIMVPITFAAGEVKADAKQSIV
                     SIQGMLDKVAPALLPALFTLLVYYLIKEKKWTTYKLVILTVIIGIIGSWLKIIA"
     gene            complement(17419..18198)
                     /locus_tag="VVR63_000597"
     CDS             complement(17419..18198)
                     /locus_tag="VVR63_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEU6128640.1"
                     /translation="MSINVFQAILIGLWTAFCFSGMLLGIYTNRCIVLSFGVGIILGD
                     LPTALAMGAIGELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVSPEAALALST
                     PIAVAIQFLQTFAYTVRAGAPETAMKHLKNHNLKKFKFTLNATIWLFAFIGFTLGCLG
                     ALSMDTLLKLVDYIPPVLLTGLTVAGKMLPAIGFAMILSVMAKKELIPFVLLGYVCAA
                     YLNIPTIGIAIVGTIFALIEFYNKPKTADHVVEEEAHDDWI"
     gene            complement(18213..18704)
                     /locus_tag="VVR63_000598"
     CDS             complement(18213..18704)
                     /locus_tag="VVR63_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000178618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEU6128641.1"
                     /translation="MTMPNIIMTRIDERLIHGQGQLWVKYLGCNTVIVANDEVSTDKM
                     QQTLMKTVVPDSVAMRFFPLQKVIDIIHKANPAQTIFIVVKDVKDALTLVEGGVPIKE
                     INIGNIHNATGKEQVTRSIFLGEEDKAALKELNQTHQVTFNTKTTPTGNDGAVQVNIM
                     DYI"
     gene            complement(18715..19905)
                     /locus_tag="VVR63_000599"
     CDS             complement(18715..19905)
                     /locus_tag="VVR63_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003074342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HEU6128642.1"
                     /translation="MIKKVTIEKIKSPERFLEVPLLTKEEVGQAIDKVIRQLELNLDY
                     FKEDFPTPATFDNVYPIMDNTEWTNGFWTGELWLAYEYSQQDAFKNIAHKNVLSFLDR
                     VNKRVELDHHDLGFLYTPSCMAEYKINGDGEAREAALKAADKLIERYQEKGGFIQAWG
                     DLGKKEHYRLIIDCLLNIQLLFFAYQETGDQKYYDIAESHFYASANNVIRDDASSFHT
                     FYFDPETGQPFKGVTRQGYSDDSCWARGQSWGVYGIPLTYRHLKDESCFDLFKGVTNY
                     FLNRLPKDHVSYWDLIFNDGSDQSRDSSATAIAVCGIHEMLKHLPEVDADKDIYKHAM
                     HAMLRSLIEHYANNQFTPGGTSLLHGVYSWHSGKGVDEGNIWGDYYYLEALIRFYKDW
                     NLYW"
     gene            complement(19917..20351)
                     /locus_tag="VVR63_000600"
     CDS             complement(19917..20351)
                     /locus_tag="VVR63_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU6128643.1"
                     /translation="MKIVLVGHGHFATGIYSSLQLIAGNQENVEAIDFVEGMSADELK
                     QKILLAISNEEEVLILSDLLGGSPFKVSSTIMGENPAKTMNVLSGLNLAMLMEAVFAR
                     MAHSFDEVVNKSVVAAQGGVVNGKELFSTDAEEEEEDFESGI"
     gene            20623..21438
                     /locus_tag="VVR63_000601"
     CDS             20623..21438
                     /locus_tag="VVR63_000601"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HEU6128644.1"
                     /translation="MTNTSFSIEQFSLKGKIALITGASYGIGFAIAKSYAEAGATIVF
                     NDINQDLVNKGIEAYREVGIEAHGYVCDVTDEDGIQAMVKQIEQEVGVIDILVNNAGI
                     IRRVPMCEMSAADFRKVIDIDLNAPFIVSKAVIPSMIKKGHGKIINICSMMSELGRET
                     VSAYAAAKGGLKMLTRNIASEYGGANIQCNGIGPGYIATPQTAPLRELQEDGSRHPFD
                     QFIIAKTPAARWGNPEDLMGPAVFLASDASNFVNGHILYVDGGILAYIGKQPE"
     gene            21457..22098
                     /locus_tag="VVR63_000602"
     CDS             21457..22098
                     /locus_tag="VVR63_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HEU6128645.1"
                     /translation="MKIALINENSQASKNHIIYDSLKEATDKKGYQLFNYGMRGEEGE
                     SQLTYVQNGLMAAILLNTKAVDFVVTGCGTGVGAMLALNSFPGVVCGLAVDPTDAYLY
                     SQINGGNALSIPYAKGFGWGAELTLKLMFERLFAEEMGGGYPRERVIPEQRNARILNE
                     VKQITHNDLMTILKTIDQDFLKDTISGKYFQEYFFENCQDDEVAAYLKEVLAK"
     gene            22129..23130
                     /locus_tag="VVR63_000603"
     CDS             22129..23130
                     /locus_tag="VVR63_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HEU6128646.1"
                     /translation="MTKILLFGEPLIRISPLDATSIGDHVASSTYFGGSEINIACNLQ
                     ALGISTKVFTALPANEIGDRFLTFLKQHQIDTSSICRLGDRIGLYYLENGFGCRQSEV
                     FYDRKHTSISQIRPNMLDMDSLFQGISHFHFSGITIAIGQEVRAILLLLLEEAKRRGI
                     VVSMDLNLRTKMISVLEAKYEFSKFARFTDYCFGIDPLMIDDQNLEMFPRDSASLEEV
                     ENRMRLLKEAYGFKAIFHTLRSSDEQDKNVYQAYALEERFEESVQLKTAVYQRIGSGD
                     AFISGALYQLLHHSSLKTTIDFAVASATLKCTLPGDHLSTSATSIENLLANAQDIIR"
     gene            23140..23769
                     /locus_tag="VVR63_000604"
     CDS             23140..23769
                     /locus_tag="VVR63_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HEU6128647.1"
                     /translation="MTKSDTIIELKKQKIVAVIRGNTKEEGLQASIACIKGGIKAIEI
                     AYTNQYAGQIIKELVDLYQDDQSVCIGAGTVLDAVTARDAILAGANYVVSPSFHAETA
                     KMCNLYSTPYIPGCITLTEITTALEAGSEIIKLFPGSTLSPAYISAVKAPIPQVSVMV
                     TGGVGLNNIPQWFAAGADAVGIGGELNKLASQGNFDRISEIAQQYVTLR"
     gene            complement(24148..24533)
                     /gene="tnpA"
                     /locus_tag="VVR63_000605"
                     /pseudo
     CDS             complement(24148..24533)
                     /gene="tnpA"
                     /locus_tag="VVR63_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596946.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(24913..28116)
                     /locus_tag="VVR63_000606"
     CDS             complement(24913..28116)
                     /locus_tag="VVR63_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored hyaluronate lyase"
                     /protein_id="HEU6128648.1"
                     /translation="MQTKTKKLIVSLSSLVLSGFLLNHYMTVGAEETTTNTIQQSQKE
                     VQYQQRDTKNLVENGDFGQTEDGSSPWTGSKAQGWSAWVDQKNSSADASTRVIEAKDG
                     AITISSPEKLRAAVHRMVPIEAKKKYKLRFKIKTDNKVGIAKVRIIEESGKDKRLWNS
                     ATTSGTKDWQTIEADYSPTLDVDKIKLELFYETGTGTVSFKDIELVEVAAQLSEDSQT
                     DKQLEEKIDLPIGKKHVFSLADYTYKVENPDVASVKNGILEPLKEGTTNVIVSKDGKE
                     VKKIPLKILASVKDAYTARLDDWNGIIAGNQYYDSKNEQMAKLNQELEGKVADSLSSI
                     SSQADRTYLWEKFSNYKMSANLTATYRKLEEMAKQVTNPSSRYYQDETVVRTVRDSME
                     WMHKHVYNREKSIVGNWWDYEIGTPRAINNTLSLMKEYFSDEEIKKYTDVIEKFVPDP
                     EHFRKTTDNPFKALGGNLVDMGRVKVIAGLLRKDDQEISSTIRSIEQVFKLVDQGEGF
                     YQDGSYIDHTNVAYTGAYGNVLIDGLSQLLPVIQKTKNPIDKDKMQTMYHWIDKSFAP
                     LLVNGELMDMSRGRSISRANSEGHVAAVEVLRGIHRIADMSEGETKQRLQSLVKTIVQ
                     SDSYYDVFKNLKTYKDISLMQSLLSDAGVASVPRTSYLSAFNKMDKTAMYNAEKGFGF
                     GLSLFSSRTLNYEHMNKENKRGWYTSDGMFYLYNGDLSHYSDGYWPTVNPYKMPGTTE
                     TDAKRADSDTGKVLPSAFVGTSKLDDANATATMDFTNWNQTLTAHKSWFMLKDKIAFL
                     GSNIQNTSTDTAATTIDQRKLESSNPYKVYVNDKEASLTEQEKDYPETQSVFLESSDS
                     KKNIGYFFFKKSSISMSKALQKGAWKDINEGQSDKEVENEFLTISQAHKQNGDSYGYM
                     LIPNVDRATFNQMIKELESSLIENNETLQSVYDAKQGVWGIVKYDDSVSTISNQFQVL
                     KRGVYTIRKEGDEYKIAYYNPETQESAPDQEVFKKLEQAAQPQVQNSKEKEKSEEEKN
                     HSDQKNLPQTGEGQSILASLGFLLLGAFYLFRRGKNN"
     gene            28339..28815
                     /locus_tag="VVR63_000607"
     CDS             28339..28815
                     /locus_tag="VVR63_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HEU6128649.1"
                     /translation="MTSLYDFSVLNQNNQATPLDSYRGKVLLIVNTATGCGLTPQYQG
                     LQELYERYQDQGFEILDFPCNQFMGQAPGSAEEINAFCSLHFQTTFPRFAKIKVNGKE
                     ADPLYVWLKDQKSGPLGKRVEWNFAKFLIGRDGQVFERFSSKTDPKQIEEAIQTLL"
     gene            complement(29037..31250)
                     /locus_tag="VVR63_000608"
     CDS             complement(29037..31250)
                     /locus_tag="VVR63_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000688702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 31 protein"
                     /protein_id="HEU6128650.1"
                     /translation="MKIFKGEFYRISVLTDKLVRLEYSRTGNFEDRTTQLIYNRDFGQ
                     NSLDYIETSNVLDIMTDYFHLHFNKGKFNAENLFIELKGNFAVYGSRWYFGESIETLK
                     GTARTLDKADGAISLEDGIISRNGIALLDDSQGFIWDEQSGYIERENQIDLYFFAYGH
                     DYRGAIRDFYHLTGSTPLLPRYALGNWWSRYWPYTSDEYLDLIDRFETEKIPLSIGVL
                     DMDWHITDIPARFGSGWTGYSWNKNLIPNPEQLLQQLHDRKLKLSLNVHPADGIRAYE
                     EAYPQVAKRLGLNVELEEPAIFDFFNPSFREAYFKDVHYELEKQGVDFWWIDWQQGTQ
                     GILDPLWLLNHYHYQDSCKNAEGGLILSRYAGPGSHRYPVGFSGDTIISWNSLRFQPY
                     FTATASNIGYSWWSHDIGGHMLGDYDEELQTRWLQFGVFSPITRLHSSRSPFNSKEPW
                     FFSETTSKIMKKYLRLRHQMIPYLYTMNVKTHEEGAPLISPIYYFYPENDESYNVPNQ
                     YFFGTELMVAPIVEKMDLTFQSAKVDVWFPEGEWYDFFSDKKYTGGVKLSVYRDISTT
                     PVFAKSGAIIPLVGSEIGMGVDLPEVVDWYVFPGKQHSFEMLEDQNGQRYKTRLSIDW
                     EMGMVELALQGDSSIVPSNRKHRIHFKGTNVSIIELPNKNDTAKFEWKDNKRTSLNDE
                     VFRLLKTASLPYELKDRLLNQFINAKNSHDLMNILHHQDKELRGRLLEMIFTSQN"
     gene            complement(31651..31827)
                     /locus_tag="VVR63_000609"
     CDS             complement(31651..31827)
                     /locus_tag="VVR63_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6128651.1"
                     /translation="MSLDIDKEKMTIMGIAFENRSVFKSVWYALSTNMIEGWRPTVSD
                     VEKLRDEALALGMT"
     gene            31974..32396
                     /locus_tag="VVR63_000610"
     CDS             31974..32396
                     /locus_tag="VVR63_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEU6128652.1"
                     /translation="MRFIVETFPIFSISNDLLQLLTSWKKQQKYELAKFGIISNPEQF
                     IFTYIDTKGNINKPLHSDYLNNKMKTIRKRHPELTHATPHKLRHTGATLAKQAGMSLE
                     AISEALIHSDTGTTQIYVNTSNVVPMAVGEFALQSLKQ"
     gene            complement(32657..33049)
                     /gene="rpsI"
                     /locus_tag="VVR63_000611"
     CDS             complement(32657..33049)
                     /gene="rpsI"
                     /locus_tag="VVR63_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HEU6128653.1"
                     /translation="MSQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTVGSYDVFVNVIGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDSRKVERKKPGLKKARKASQFSKR"
     gene            complement(33068..33514)
                     /gene="rplM"
                     /locus_tag="VVR63_000612"
     CDS             complement(33068..33514)
                     /gene="rplM"
                     /locus_tag="VVR63_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HEU6128654.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKIYYTHSNHPGGLKQISAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGAEHTHAAQQPEVLDISGLI"
     gene            33871..34188
                     /locus_tag="VVR63_000613"
     CDS             33871..34188
                     /locus_tag="VVR63_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HEU6128655.1"
                     /translation="MAFTNTHMRSASFGIVTSLPDDIIDSFWYIIDHFLKNVFELEEE
                     LEFQLLNNQGKITFHFSSQHLPTAIDFDFNHPFDPRYPPRVLVLDMDGRETILLPEEN
                     DLF"
     gene            complement(34233..35045)
                     /gene="folK"
                     /locus_tag="VVR63_000614"
     CDS             complement(34233..35045)
                     /gene="folK"
                     /locus_tag="VVR63_000614"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HEU6128656.1"
                     /translation="MDQLQIKDLEIFAYHGLFPSEKELGQKFVVSAILSYDMTKAATD
                     LDLTASVHYGELCQQWTTWFQETSEDLIETVAYKLVERTFESYPLVQEMKLELKKPWA
                     PVHLSLDTCSVTIHRRKQRAFIALGSNMGDKQANLKQAIDKLRARGIYILKESSVLAT
                     EPWGGVEQDSFANQVVEVETWLPAQDLLETLLAIESELGRVREVHWGPRLIDLDLLFV
                     EDQILYTDDLILPHPYIAERLFVLESLQEIAPHFIHPILKQPIRNLYDALKK"
     gene            complement(35204..35758)
                     /gene="folE"
                     /locus_tag="VVR63_000615"
     CDS             complement(35204..35758)
                     /gene="folE"
                     /locus_tag="VVR63_000615"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HEU6128657.1"
                     /translation="MDTQKIEAAVKMIIEAVGEDANREGLQETPARVARMYQEIFSGL
                     GQTAEEHLSKSFEIIDDNMVVEKDIFFHTMCEHHFLPFYGRAHIAYIPDGRVAGLSKL
                     ARTVEVYSKKPQIQERLNIEVADALMEYLGAKGAFVVIEAEHMCMSMRGVRKPGTATL
                     TTVARGLFETDKDLRDQAYRLMGL"
     gene            complement(35739..37061)
                     /locus_tag="VVR63_000616"
     CDS             complement(35739..37061)
                     /locus_tag="VVR63_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEU6128658.1"
                     /translation="MKEIQNNQWIANYRTDQPHFGLERMEELLALRGNPHLKLKVIHI
                     GGTNGKGSTIAFLKKMLEKLGLRVGVFSSPYLIHYTDQISINGESIPEARLEALMGDY
                     QSLLEGESATNLQGTTEFEIITAIAYDYFASEQIDVAIMEVGMGGLLDSTNVCQPILT
                     GITTIGLDHVALLGDTLEAIAEQKAGIIKQGIPLVTGRIAPEALAVIDRIAEGKDAPR
                     LAYGIDYQVSHQKSVVTGEVFDYTSVVRQGRFQTGLLGLHQIENAGMAIALLDTFCQE
                     DGRELASNHLLAQALEETSWPGRLEIVSRDPLMILDGAHNSHAIKALLATLQERFADY
                     RKEILFTCIKTKALEDMLDLLEQIPDTELTLTHFDDSRATDENVLKEAAKSRNLSYQG
                     WQDFLEQKLTDKKEEKQTVRIVTGSLYFLSQVRAYLMERNNENGYTKD"
     gene            complement(37063..38040)
                     /gene="folP"
                     /locus_tag="VVR63_000617"
     CDS             complement(37063..38040)
                     /gene="folP"
                     /locus_tag="VVR63_000617"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HEU6128659.1"
                     /translation="MVKSLEGVTDMSSKANHAKTAICGIINVTPDSFSDGGQFFALEQ
                     ALQQARKLIAEGASMLDIGGESTRPGSSSYVEIEEEIQRVVPVIKAIRKESDVLISID
                     TWKSQVAEAALAAGANLVNDITGLMGDEKMAHVVANAGAKVVIMFNPVMARPQHPSSL
                     IFPHFGFGQAFTEEELADFEKLPIEELMETFFERALARAEEAGIAQENILLDPGIGFG
                     LTKKENLLLLRDLDKLHQKGYPIFLGVSRKRFVINILEENGFEVNPETELGFRNRDTA
                     SAHVTSIAARQGVEVVRVHDVVSHRMAVEIASAIRLADEAEDLDLKQYK"
     gene            complement(38130..38837)
                     /locus_tag="VVR63_000618"
     CDS             complement(38130..38837)
                     /locus_tag="VVR63_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU6128660.1"
                     /translation="MKEKNMWKELLNRAGWLLIFFLATILYQIPIGVTAILTLNAVPL
                     LQSGLIVAGISIVVLALFIFGARKTQLASFNFSFFRAKDLARLGLSYLVIIGSNILGS
                     ILLQLSNETTTGNQSQINDMVQNSSLISSFFLLALLAPICEEILCRGIVPKKIFRGKE
                     NLGFVVGTIVFALLHQPSNLPSLLIYGGMSIVLSWTAYKTQRLEMSILLHMIVNGVAF
                     CLLALVVIMSRTLGISV"
     gene            complement(38890..40308)
                     /locus_tag="VVR63_000619"
     CDS             complement(38890..40308)
                     /locus_tag="VVR63_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HEU6128661.1"
                     /translation="MDKLFKLKENGTDVRTEVLAGLTTFFAMSYILFVNPQILSQTGM
                     PAQGVFLATIIGAVAGTLMMAFYANLPYAQAPGMGLNAFFTFTVVFGLGYSWQQALAM
                     VFICGLISLIITLTNVRKMIIESIPNALRSAISAGIGVFLAYVGIKNAGFLKFTIDPG
                     NYTVVGEGADKAKATIAANSSAVPGLVDFNNPAVLVALAGLAITIFFVIKGIKGGIIL
                     SILTTTVLAIAVGLVDLSSIDFANNHVGAAFEDLKTVFGAALGSEGLGALISDTARLP
                     ETLMAILAFSLTDIFDTIGTLIGTGEKVGIVATNGENHQSAKLDKALYSDLIGTSIGA
                     IAGTSNVTTYVESAAGIGAGGRTGLTALVVAICFAISSFFSPLLAIVPTAATAPILII
                     VGIMMLASLKNIHWDDISEAVPAFFTSIFMGFSYSITQGIAVGFLTYTLTKLVKGQAK
                     DVHVMIWILDALFILNYISMAL"
     gene            40498..41310
                     /locus_tag="VVR63_000620"
     CDS             40498..41310
                     /locus_tag="VVR63_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU6128662.1"
                     /translation="MTKKIIAVDLDGTLLNSDSQISDFTKKTIKKVAEKGHQVIITTG
                     RPYRMSKDFYRELGLDTPMINFNGSLTHLPDQVWDFEKCLTVDKKYLLDMVQRSEDIQ
                     ADFIAGEYRKKFYITNPNEEIANPKLFGVEAFQPEDQFQPELVTKDPNCILLQTRASD
                     KYALAKDMNAFYQHQLSINTWGGPLNILECTPKGVNKAFALDYLLKIMNRDKKDLIAF
                     GDEHNDTEMLAFAGKGYAMKNANPELLPYADEQISLTNDQDGVAKTLQDLFL"
     gene            41649..42668
                     /gene="adhP"
                     /locus_tag="VVR63_000621"
     CDS             41649..42668
                     /gene="adhP"
                     /locus_tag="VVR63_000621"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HEU6128663.1"
                     /translation="MKAVVVNPESTGVAIEEKVLRPLETGEALVEVEYCGVCHTDLHV
                     AHGDFGQVPGRVLGHEGIGIVKEIAPDVKSLKVGDRVSVAWFFEGCGTCEYCTTGRET
                     LCRTVKNAGYSVDGGMAEQCIVTADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAKV
                     EPGQWVVLYGAGGLGNLAVQYAKKVFNAHVIAVDINNDKLTLAKEVGADIVINGLEVE
                     DVAGLIKEKTDGGAHSAVVTAVSKVAFNQAVDSIRAGGRVVAVGLPSEMMELSIVKTV
                     LDGIQVIGSLVGTRKDLEEAFQFGAEGLVVPVVQKRPVEDAVAIFDEMEKGQIQGRMV
                     LDFTH"
     gene            42901..43890
                     /gene="manX"
                     /locus_tag="VVR63_000622"
     CDS             42901..43890
                     /gene="manX"
                     /locus_tag="VVR63_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HEU6128664.1"
                     /translation="MSIGIIIASHGEFAAGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYAKFNNAVAAFDAEDEVLVLADLWSGSPFNQASRVMGENPERKFAIITGLNLPMLIQ
                     AYTERLMDAAAGVEKVAANIIKEAKDGIKALPEELNPVEEVASAAAAPVAQTAIPEGT
                     VIGDGKLKINLARLDTRLLHGQVATAWTPDSKANRIIVASDNVAKDDLRKELIKQAAP
                     GNVKANVVPIQKLIEISKDPRFGETHALILFETPQDALRAIEGGVPIKTLNVGSMAHS
                     TGKTLVNTVLSMDKEDVATFEKMRDLGVEFDVRKVPNDSKKDLFDLINKANVK"
     gene            43918..44721
                     /locus_tag="VVR63_000623"
     CDS             43918..44721
                     /locus_tag="VVR63_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HEU6128665.1"
                     /translation="MSIISMVLVVVVAFFAGLEGILDQFQFHQPLVACTLIGLVTGHL
                     EAGIILGGSLQMIALGWSNIGAAIAPDAALASVAAAIIMVLGGDFTKTGIGVAQAVAI
                     PLAVAGLFLTMIVRTISVGLVHTADAAAKKGDFGAVERAHFIALLFQGLRIALPAALL
                     LMVPTETVQSILSAMPDWLKDGMAIGGGMVVAVGYAMVINMMATREVWPFFALGFVLA
                     AVSDITLIGFGAIGVAIALIYLHLSKTGGNGGGGAATSNDPIGDILEDY"
     gene            44745..45656
                     /locus_tag="VVR63_000624"
     CDS             44745..45656
                     /locus_tag="VVR63_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEU6128666.1"
                     /translation="MTEKLQLTKSDRKKVWWRSTFLQGSWNFERMQNLGWAYTLIPAI
                     KKLYTKKEDQIAALERHLEFFNTHPYVAAPVMGVTLALEEERANGVEIDDAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGSLGASLALTGNILGPLLFFVAWNLIRMSFLWYVQE
                     IGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVNIKFAFDVSKVQLDEKA
                     YIHWDKLPEGSKGIQEAFAQVGQGLSQTPEKVTTFQQNLDMLIPGLSGLLLTLLCMYL
                     LKKKVSPITIILALFAVGIVAHVLHIM"
     gene            complement(45712..47046)
                     /gene="pepC"
                     /locus_tag="VVR63_000625"
     CDS             complement(45712..47046)
                     /gene="pepC"
                     /locus_tag="VVR63_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000991632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HEU6128667.1"
                     /translation="MNAIQESFTDKLFANYEANVKYQAIENAASHNGIFAALERRQSH
                     VDNTPVFSLDLTKDKVTNQKASGRCWMFAALNTFRHKLISQYKLENFELSQAHTFFWD
                     KYEKSNWFLEQVIATSDQELTSRKVSFLLQTPQQDGGQWDMVVSLFEKYGVVPKSVYP
                     ESVSSSSSRELNAILNKLLRQDAQILRDLLVSGADQVTVQAKKEDLLQEIFNFLAMSL
                     GLPPRKFDFAYRDKDNNYKSEKGITPQEFYKKYVNLPLEDYVSVINAPTADKPYGKSY
                     TVEMLGNVVGSRAVRYINVPMERLKELAIAQMQAGETVWFGSDVGQLSNRKAGILATD
                     VYDFESSMDIKLTQDKAGRLDYSESLMTHAMVLTGVDLDENGKSTKWKVENSWGDKVG
                     TDGYFVASDAWMDEYTYQIVVRKELLTAEEQAAYGAEPIVLAPWDPMGALAK"
     gene            complement(47263..47985)
                     /locus_tag="VVR63_000626"
     CDS             complement(47263..47985)
                     /locus_tag="VVR63_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEU6128668.1"
                     /translation="MRLDKFLVACAVGSRTEVKNMLKSGRVTVNGKKEKSAKLQIDEE
                     RDEIRFDGQVLEYEEFVYYMMNKPKGVISATEDPKHRTVLDLLDDIARSKEVFPVGRL
                     DIDTHGLLLLTNDGKLAHALLSPKRHVDKTYLAQVKGIMTQEDAETFAKGIPLKDFTC
                     QPARLELVSVDTKKNQSQIRVTIAEGKFHQVKRMVGYCGKEVVDLQRLTMGTLVLDEN
                     LQRGEWRRLTKEELEILRANII"
BASE COUNT        14008 a        10698 c         8801 g        14547 t
ORIGIN      
        1 gaggctcttt tgtcttgttc ttgtttcaat tgactatatt atcagcgtaa tagtctaata
       61 gatagttaaa tgtagttgga tttccactaa aggttgatga gtaagttttt gtatctgaac
      121 ctgattggcc gcaagcagct aaaagcaaag cagatgcaaa agtcaggcct gcactaagga
      181 cacgcttctt tatgttcatc ttctttctcc ttaatagtgg gaatttgtaa agttaattga
      241 atttcgagaa tgaaagttta taaaccttgg ttataaaaaa caaaggattt ctgcttttta
      301 tacagtcctc ccttgttttt atatgatttc aattttaaat ttttctgcaa aaaatattta
      361 tagtaattcc acacagaaag catcccatgg aactaagatt tgtttttcaa agacttcttg
      421 agctagggtg ttttcaatca agacagattt gacttttcct tctactgtca agtcttgctc
      481 ttcattggac aagttagcca caactaggaa gcgacggtcg ccatccttac gtatataagc
      541 aaagacctta tcagccgtat caagcaattc aaagtcagct cgaattagcc agctattctc
      601 cttgcgaatt tggaccagtt tctgataggt atagaaaata gaatctggat ttgccagcgc
      661 ttcttggaca ttgatcatct cgtaatttgg attaaccgcc aaccaaggtt gacctgttga
      721 gaaaccagcg tttttgctct cgtcccattg cataggggta cgagcattgt cacgtccaat
      781 aacacggata ctgtccatga tttcttcaat cggaacacct ttttcaagag cctcatgcgc
      841 atagttgaga gattcaatat cttctacttg atccagtgtt tcaaacggat agttggtcat
      901 cccaatctcc tcaccttggt agatataagg agttcctctc ataagatgaa gcaagattgc
      961 aaaggctttg gcagattttt cgcggtattc ttggtcattt ccccagattg agacgatacg
     1021 agggaggtca tgattgttcc agaagaggga attccaaccg tcctcaactc ctaactctgt
     1081 ctgccatttg ttgaagattt cttttaactt agcgatattc agctcttttt gatagtgcca
     1141 tttaggctga ccttcctgat actgaagacc gatatgttca aactggaaga ccatagacaa
     1201 ttcttgcccc tttggatcag agtagagctt ggcaatctct ggcgttgctc cccaagtctc
     1261 ccctactgtc aagagatcct tatctccaaa ggtcgcctga ttcatttcct tgagataggg
     1321 atggagcata ggaccattat tgactacctt ctcgtcagga attttgccaa tcatgtcaat
     1381 aacatccata cggaaaccac caataccttt atcaatccag aagttcatca tctcataaat
     1441 tttctggcga agtttttcat tttcccagtt gagatccggc tgttttttgc tgaaaaagtg
     1501 gagatagtat tgacctgact tttcatcgta ttcccaagca gacccactaa agatagaatc
     1561 taggtcattg ggttcatcgc gccagatata gtagtctcgc tcagggctgt cagtattttc
     1621 acaggcttcg acaaaccaag catgttcatc tgaggtatga ttaaccacca agtccatgat
     1681 gatacgaatg tcacgcttct tagcttctgc aatcagctga tccatgtcct ccatggttcc
     1741 aaaaatagcc gcaatcgctt gataatcagc aatatcgtag ccattatcat ccatagggct
     1801 gtcataaacg ggagaaagcc aaatcgctgt gattcctaac ttagctagat agtccaactt
     1861 actggtaata cctggcaaat caccaactcc atctccatta ctatccataa aactctttgg
     1921 atagacttga tagactacgg cattatgcca ccatttttct tgcatcttct tacctcatta
     1981 ttttcataat ctatagtcta tgatagcact ttttaaaatt ttgtgcaagc gtttgcctaa
     2041 tctttttgat tcctttttta actccatagt ttcctaactt ccaatttttt attataatag
     2101 aggtcagagg taaaaaaatg aaaaaacaag cttttagttc tgaacaatat ttgaatttac
     2161 aacgcgacca tattttggag cgcattaacc aatttgacgg caagctctac ttagagtttg
     2221 gcggtaaaat gttagaagat ttccacgctg ctcgtgtcct tcctggttat gaacctgaca
     2281 acaaaatcaa gctcttgcaa gaattgaaag agcaggttga ggttgtgatt gccattaatg
     2341 ctagcaacat tgaacattcc aaagcacgtg gcgacttagg catttcttat gaccaagaag
     2401 ttcttcgttt gattgacaaa ttcaatgaat tagggatttt tgttggttcc gttgtcatta
     2461 cacaatacgc tggccaaccc gctgcagatg ccttccgcaa ccaacttgag aaaaacggaa
     2521 ttgattctta tcttcattat ccaatcaaag gatatccgac ggatatggat cacatcattt
     2581 ccccagaagg catgggcaaa aacgactaca tcaaaaccag tcgcaacttg attgtcgtaa
     2641 ccgctcctgg acccggttct ggaaaattgg caacgtgtat gtccaatatg taccacgacc
     2701 aaatcaatgg catcaaatct ggctacgcta aatttgaaac cttccctgtt tggaatcttc
     2761 cccttcatca tccagttaac ttggcttatg aagctgcaac agctgacctt gatgatgtca
     2821 acatgattga ccccttccat cttcaaacct atggagaaac cactgtcaac tacaaccgtg
     2881 atatcgaaat cttcccagtg ctcaagcgca tgttggaacg tattctcgga aaatcaccat
     2941 acgcttcacc gacagatatg ggtgtcaaca tggttggttt cgctattaca gatgacgaag
     3001 ctgctgtcga agcttctaaa caagaaatca tccgccgtta ctatcaaaca gttcttgact
     3061 tcaaagctga aaaagttagc gaagctgccg tcaagaaaat tgagttgctc atgaacgacc
     3121 tcggtatcac acctgcagac cgtaaggttg ctgtcgttgc gcgccaaaaa gcagaagaaa
     3181 ctggtggacc agccctagcc tttgaattgc caaatgggga aatcgtcact ggtaagaact
     3241 cagaactctt tgggcctaca gccgctgcct tgatcaacgc catcaaaaaa tcagctgaca
     3301 tcgctaaaga agtaaaacta atcgagcctg aagttgttaa gccaatccaa ggtcttaaaa
     3361 tcgatcatct cggtagccgc aatccacgcc ttcattcaaa tgaaatcctg attgcacttg
     3421 ctatcacagc tacagaaaat cctgatgctg cccgcgctat ggaagaactc ggcaacctca
     3481 aaggaagcga agcccactca accatcatct tgactgatga agacaagaat gtccttcgta
     3541 aactgggtat caacgtaacc tttgacccat actaccaata cgaccgctta tatcgtaagt
     3601 aaagatttca acctctccag cctcggagag gttttctctc tgtctcagga gcaaccttta
     3661 tgatataatg agagaagaaa actgaaagga tttaccatgt caaaagaagt tattgtcgaa
     3721 agttttgaac ttgaccacac cattgtcaaa gcaccctatg ttcgcttgat tggggaagaa
     3781 acaggaccaa aaggagacat catctccaat tatgatattc gcttggtgca accaaacgaa
     3841 gactctatcc ctactgccgg ccttcacact atcgagcacc tcttagccaa actcatccgt
     3901 acccgcattg acggcatgat tgactgttca ccatttggtt gtcgcacagg cttccacatg
     3961 attatgtggg gacgtcacac cagtgctaaa atcgcagctg ttatcaagga ttcgctcaag
     4021 gaaatcgctg aaactactac ttgggaagat gtcccaggga caaccatcga atcttgcgga
     4081 aactacaagg accacagcct cttctctgct aaagaatggg caagactcat cttggaacaa
     4141 gggatttcag atgatgcctt tgaacgtcat gtgatttaaa atcgagtagg ggataatctc
     4201 tagcccctct cacaccaccg tacgtgccgt tcggcatacg gcggttcaac taacttttaa
     4261 cgcatgtcgt tcaaggtaat aatccaaaca cgaaaccagt ccacgttttt caaggactgg
     4321 ttttgatata gcacgtttaa gtaccgactt ctgagctact aattgataat ggtcgcccca
     4381 gccagatacc ttatctgcta tccatttagg aactcctaac ttaagcaatc cccataatcg
     4441 tctcgatttc ttcttccatt gcttccagat aatcactcgt aggcgagtat gcaagcgctc
     4501 atctatgcta gtgactatac ttttcatatt tcccaatgag aaatagttta tccatcctcg
     4561 aacagacaaa ttcagttgct ctcgtgattt acacatatag gctacgacta cctttttgaa
     4621 ctttagagtt tgaggcccct tatccgctat atacgcctta ttatcacgtt cctattcgta
     4681 gagccacgat ttcgctatcc cttcctctga cgattcttat ttccagcgtc agacttaaaa
     4741 cggtctatcc ccagaccgtt ttaatccgct acctcacgat agtcaggctt gggaatcact
     4801 attgggagca ccggtagcag gtacccaccg aggacttaca cctcagatat atagtaaaat
     4861 gaaataagaa caggacaaat caatcaggac agtcaaatcg atttctaaca atattttaga
     4921 agtagatgtg tactattcta gtttcaacct actgtacgac atgcccgtcg tacctcaaaa
     4981 ggaaccagtt ttttcagctg gctccttctt ttttatcctc aaaattctgt cttaggcttt
     5041 ctcacgaata accaaaacgc catctttcat atctgcttcc agatgtttag catctaaatg
     5101 atccaagtgg aagtctgtca ccttatcacg aatttcttgt tcaaccacgc gacggagagg
     5161 acgaaccccc atgacttcgt cgtaaccttc ttctgtgata taatctttag ccgcttgact
     5221 gactaccaag tcaatgtctt tcttagccaa ggtttggtta acttcagcca acatcaaatc
     5281 tacaatctta gaaaggtctt ccttagtcaa ttgtgagaac tcgatgactg cattaaagcg
     5341 gttgaggaat tctggacgga agaagggttt caaacggtcc atcaattctg gtttatccgc
     5401 atcttctgtc aagttggctt catagccaaa tccagcattt gaggtcgcaa taatgacagt
     5461 gttcttgaag tttactgtat ttccttgacc atctgtcaaa cgaccatcat ctagaacttg
     5521 gaggagaagg gtaataactt gaggatcagc cttttcaatt tcatccaaga gaatgataga
     5581 gtatggattg cgacgaacac gttctgttaa ggtattgcta ttgtcatcat aacccacata
     5641 gcctgctgtt gtaccaatta gcttagaaac agctgtgcgg tcactgtatt cagacatatc
     5701 caaacggata atcgcatcct gggttccaaa catatcgagt gccaattgct tagcaagctc
     5761 cgtcttacca accccagtag accctacaaa gaggaagctg ccgattgggc gatttccttc
     5821 atcaaaacca gcacggttac gacggatagc acgagctaca gcttctacgg ccttatcttg
     5881 accaatcacc ttgttttgca agcgatgagc catatctttc aaacgttcga tatctgaagc
     5941 tcccatttgc gatactggga tacctgtcat tcgttccaca gattcagcca catcgttgac
     6001 acttgcagtc actttcatat cttctgtgtg gttttcgatt ttcctttcca attctgcaat
     6061 gcgtgtttta tagtttagag ctgcttcaaa atcttctgct tcaactgctt tttcttgctt
     6121 gtctttttcc gtttcgattt ctcgttcaac agcatgcaca tctgttactg gatgttgagc
     6181 cgccaagtga gcagccgtta catcgacaag gtcaatagcc ttatctggca agctacgttg
     6241 aggaatgtat tgaacagaat aatccaccgc tgctttcaag acttcgtctg gcaagatgac
     6301 attgtggtgt tgttgataga ggtcacgaat gccttgaaga attttaaaag tattctctgc
     6361 tgaaggagca ttgaccttca cttcgttgaa acgacgagca agagcagcat tcttcaagat
     6421 ggtgttacgg tattcgtctt gagttgttgc cccaatcact gtcaattctc cacgagagag
     6481 agctggcttg agaatatccg caagcccttt agaaccactg tctccaccag tgctaccagc
     6541 accaagaatt tggtgaattt catcaaagaa gaggataata ttccctgctt ctttcacttc
     6601 attgactaag ttttggacat tttcttcaaa gctaccacgg tattgagtac cagcctcaag
     6661 acctgagata tcaatagaaa taatttcctt gttcttgata gcagcaggaa catctccgtt
     6721 cacaatggct tgcgctagac cttcgacaac tgctgtctta ccaacacctg catctccgac
     6781 caaaacagga ttgttcttgg tgcggcgtga gaggatttca gatgtttctt gaatttcctt
     6841 gtttcgtccg ataacaggat ccaacttgcc ctcacgcgct tctgctgtca agtttcgacc
     6901 tagttttgca aggacaccgt cttgtttcat acctgatgcc tgttgtggca tttgcacatc
     6961 agtttctgca tttcctggta attgaccagt cgcacgatag tgagcaaatt cctcaggtgt
     7021 gacttcgcgt ccattaatta agtaacggcg attttcagaa ctatatcctc gcataccacc
     7081 catcaattgg ttaaataaat catccatgtt attaaaatta ttaaagttgt tattcatatt
     7141 ctttacctct ttttgtttac ttagttatga ttactgatat tgactatctt tgaccattgt
     7201 tttaaaaaat ttagactagt taaaccgcta ccctacgtac tatttctggt ttttcttttt
     7261 caagcaggag tagaccatct ttacttctga agatttctag atgaaacata gacccacctc
     7321 tttctatttt actttaaata agtgttctag taaggctttc atttacctta cgttcataat
     7381 atactacatt ggtcagaaaa ggtcaagagt tttggcttta actgaccaat atttttttac
     7441 actcttcgaa aacctcttca aaccacatca gcttctcctt atctacaacc tcaaaaccat
     7501 gttttgagct gacttcgtca gttctatcaa ccatctcaaa actatatatt aaaatgaaat
     7561 aagaacagga caaatcgatc aggacagtca aatcgatttc taacaatatt ttagaagtag
     7621 atgtgtacta ttctagtttc aatatactat attttgagca gcctaaagtt agctttctag
     7681 tttgttcttt gattttcatt gtgtatttaa atacaaaaac accctgaaac atcaggatgc
     7741 cattcttaca ttaaatacaa aattgctagg gtcaggagac ttgctagaag tcccactccc
     7801 caaaagaaga agtcaacctt ccactcgctc caaggatttc ctttaccaga caatccccca
     7861 agctcaaaat ggtgatggac aggcgtcata cggaaaatac gtttaccacc tgtcagtttg
     7921 aaataactga cttgcatcat gaccgaagtt gtttcaaaaa catacacaat tccgataatc
     7981 aagagagtcc attcttggtg gagagccata gaaatcgcgg ccagcattcc accgagagcc
     8041 aaacttccca catctcccat aaagacttta gcaggcttat ggttaaagac gaagaaaccg
     8101 agcaaaccac caatcatggc tagaatcacc agaagaatat ccatctgacc ttgcacatag
     8161 gcaataactc cataggcaga caagctaatc acaacggaaa tactagctag accgtcaata
     8221 ccgtctgtca agttgactgc atttgaaaaa ccgactagcc agaaaagagc gaagataata
     8281 tagaaaatcc ctagatgcac ttggtaacta aagacggaaa gcatatcacc tccacgctca
     8341 tagaaaagat agaagataac tccacctaga agctgaagag ctaatttttg cttgggatta
     8401 agcccctcat tgatcttacg aaagacctta aggaagtcat ctaaaaatcc gaccaagcca
     8461 tacaagacca agatgaacaa aatcattccc acattattgg tcaattgttt tgaaaaaaga
     8521 gcaagaagga aactcaccac aactgcagca atgaggaaaa caagtccccc catagttggc
     8581 gtcccagctt ttgcctgatg ctgtttgaca tcctcatgca tctgctggcc tgtaatttgc
     8641 gcctttctat aaaattggat aaaggccgga attcctacta aagttattaa aaatgtcaca
     8701 actccagcac tgatagaaat aaacatatta gtctcctaaa gttaatttaa tttttttaat
     8761 gtttttgata gctgtattag tccgaacatc ttgcttctga acaacggaac ctgaaccttc
     8821 aaattccagt tcaatatcca accatttagc aaaggtctcg gcagtctctt ttttccagcc
     8881 atacatgtct ggaatttctt ctaccttatc cgataaaagg agaacttgtt ggtttggtgc
     8941 aagattggtc ccttcttcta cagaagtctc tttaatcttt gttccagtac ctacaacgat
     9001 tggttgcaca atatttcggc gtaaggcttc cgccaactca ccaggtgaaa tatccttgat
     9061 gctaggcatt gcataagaag attctgtcgt aactttatct aaatttttgg ctggagattg
     9121 aagattgaga gattctttca tagctgaagc ccgctccaag attggggtgg caaattctcc
     9181 caactggata cctgaataat gctcaggctg ttgaaccgtt acatacaaga taaaatcagg
     9241 attttcagca ggattcatag tcacaactga gaaaatataa ttggtagaac caaccaagta
     9301 tcctccattt ttctcatcag cgatttgagc cgtaccggat ttaactgcta cattttgtcc
     9361 aggaactgtt ataattggct ttcctgtgta gtgattatac atagttccat atagagggtc
     9421 cgtcccaact aagatcatgt gatttcgagt tgtgcttgct gcctctttgg aaacaggatt
     9481 tcctactatt tctttttgtg acttacgtac agactgattg ttagtatcat aaatagcact
     9541 tataaatttt ggctccagca taactccatc attagcaata gctgtaaagg cacgaagcat
     9601 ttgtgtttgt gtcactgaaa ttccttgccc aaatgagctt tgagcaatac taacaatatt
     9661 atcagctgga agttgaccag cgtattcatc tgtcaagcca aagcgagttg gaaccccaaa
     9721 tttaaagcgt tttagataat ccaaccaagt agcatctccc attttttgtt caagtagact
     9781 cattccaaca ttactggagt gagcgaaacc ttgtaagaaa gtcatcatcc caccagtagt
     9841 caaaccatca ttaacatccc aatctcgagt cgtcgcatcc gctattttga attcactgct
     9901 attgaagtat tctccacttg ggaaggtatt attatcaata gaagaagcta acgtcataac
     9961 cttcatggct gatcctggtt catagttact ttgataaaga atatcacgcc aaacaaagtc
    10021 ctcagtgatt ccttctttag tatctgcatt aaaggtaggt cgttgggtgg tagcgaggat
    10081 ttcaccggtc tttgcactga ccaaggtcgc ggtcatatac ttacctttta ctttttctag
    10141 aaaggcatcc atctgagttt ccatgaaaga ttgtagcgga ctagacaatg ttgtataaac
    10201 atccttgcca tccacagttt gttgcgatac cagttctgta cctggtacga tatttcctac
    10261 acggtctttt tcataggtaa taataccgtc tgtccctgca agaatactgt tcaaggaact
    10321 ctccattcca gaggttccca gtaagctctt gctgccatct tcattttcat ggagctgagc
    10381 tagtccgata aaactagaag caaattgtcc gtttggataa ctacgattgg gactggttgt
    10441 aaaatcaatc cccttgacct ctgcagtttc caattctttt ttgatagaca tcatattggc
    10501 ataggtaatc ccattgccct tcgaaccaaa ggaaacttgc ttgagattag gttgcgagag
    10561 ttgctctctt acataggatt cttccatgtc cagatactta tgaaagacct ctgcaacctt
    10621 gttaaattgt gttttttcta cgtaaagaat cttacccgtt gctgacttat agttctcatc
    10681 aatgaccgca tagacattat aggaggttgc atcctcagca atcgggactc catttcggtc
    10741 ataaatagtc ccacgtttgg caggaactgt acgggtggtt tgatgaacct tcttagcttc
    10801 cttcgctaaa tctgttccaa agcgagtgcc tgtcccaata atgaccgcaa aattgactaa
    10861 aaaaatggca aaaacaaaga cagataataa actcagactt tttccaactc tgcgtctgtt
    10921 ttcagccggc gatttccgat ttttggtcgc ataacggatt actctttttg tccacttcat
    10981 atcttactcc gctattctaa tattttcatt gtttaattgc aaatcgtgtg aattggcaat
    11041 ttctttcaaa cgttctgcac gtaatagttc attgacctct tgcttggcat cgtccaattc
    11101 ggtcttcttt tcctctatct gcgcattgat ttttgtcaaa tcattctgca cttgcaagag
    11161 cttggtctgc ataaaaataa tactaatggc tacaataaga gtggttacag caatggaaaa
    11221 gtaaaaagct ttttccacac gcgaaaaccg tttaagttgc atctgtagta tttgacctgt
    11281 tttttccatt ttttctgcca tctttttccc tcttacttgt gaatttttct gaccacgcgc
    11341 aacttggctg agtgcgagcg gttattggct tctaactctt ccgcacttgg caagattggc
    11401 ttacgggaca ccaattccat cttgggcttg agatcatctg ggatgaaagg caagcctttt
    11461 ggaacttcaa ctgttgaagc ttccttgaac aattgcttgg tcaagcggtc ttctaaggaa
    11521 tgaaaggtaa tcactgaaat tctaccatcc agagccaaca tatccatagc ctgctggatg
    11581 gactcatctg ccgctcccag ttcatcattg acttcaattc gaatagcctg gaaaatctgc
    11641 ttagcaggat gacccttctt cttgagttcc ttggcaggtt tgaccaactt gataatctct
    11701 gctaactcag tcgttgtctc aatcggcttc acttcacgcg cttgctcaat cttacgcgca
    11761 atctgtttag agaatttgtc ctctccatac ttgaagaaaa tacgaaccaa gtcatgatag
    11821 tcataattgt tcaccacttc ataggctgtc agactagcat cctgattcat ccgcatgtcc
    11881 agtggcgcat cctttttata agaaaaacca cgctcacgct ggtctaattg aggactagac
    11941 actcccaagt cataacaaat tccatcaatt tcctgaacac cagtttcgcg caaacgtgcc
    12001 tgtaaatgac ggaagttgtc cttgataaag gtcaccattc ccttctcaat gtaaggtgcc
    12061 aagcgttttt gcgcattgtc aatggcattc tgatcctggt caaaggcata gagatggcct
    12121 ttttcactta atttacttaa taaatactcg ctatggcctg ctccacccaa agtcgcatca
    12181 acgtagatac cgtcaggttt tacgtcaagc atatcaatcg tttcgtggag taagaccgtt
    12241 acatgatgaa attcttttgt catatcttat ctattttacc acaaatccga ccagcttgca
    12301 cttgtcagac aaataggaca aggagactac tatttcttca aaaaatatgt caaaaatact
    12361 tgacacttta tgtttaaaag actataataa agtcaaatat atacgacaca aatcagaaag
    12421 gagaccagat gaatcgtgtg aaagaatttc gcaaggaact gggcatttcc cagctcgagc
    12481 tcgccaagga tatcggtgtc tcgagacaga ccatcaatat gattgaaaac gacaagtaca
    12541 atccaactct ggaactctgt ctcaatctcg ctcgcagcct ccaaactgac ctcaacagtc
    12601 tcttttggaa ggaagatttt taaaaaagga gcaaactcat gaaaaaagaa aagaaacagt
    12661 tacgttatcc tggtctgaaa gcaggttcga tttatggaac agtgatattt tttataattc
    12721 cactcattga taccctaaca agtgaaaatc caaattttat cagttctctt ctaaatacaa
    12781 aacatatttt taaaactata ctgggagctt tctttttcgg agtgatgata catattgtcg
    12841 actcacttcg tattgcaaga gctaaaaaag accaggatta ggaggtgcct tatgaaatca
    12901 ctagctagac tactgatcat tcatgttttt atcagtattt tccttttctt cgcccttatt
    12961 tcaggagctg tttctcatac agttttacta ctcctactcc tctttcttcc tgcgctcaat
    13021 aaaggacttg agaaaataca atcaaaacgg atacctgtcc tcaacgcagc cctcttcttt
    13081 ctcctcatat cctttccaca acttttaacc aaccctgtcc aatggaaatt ttcaatattc
    13141 ctagtcgtaa ccatcatttc aagtttggcc tacttctata acttttatca agtagttaaa
    13201 gaagtagatc aaaaacagtt gatttaggag cttgctccca taatttctca tttcataggc
    13261 aaataatccc acctagcttg ttctaggtgg gattatttta tttcttaaca gaaattgcaa
    13321 gtcattttcc ttcattttag aaagtcgact ctttccaatt cacactacaa tccaagactt
    13381 gttgcctttc ttcttgattg cggccttcaa tctgatcaat caaaatcttt gtagcctgtt
    13441 gtccttcctc aaaggagggc tgaaccagcg tcgaaacact tggagaagaa aagcaagtcc
    13501 actccgtatt gtcaaaacca atcaacccaa cttgtggcaa gttataattc aactctttga
    13561 taacggtaaa gactagaggt agggcccaac agttagggat aaataccaga gttttttcat
    13621 cgggatcgat ttctttttgt aaaaattcct taatttgttc caaattcgta tgcttatctt
    13681 caatggttag actggcgtga cgcatattag catctgttaa agcatccaca aaaccacttg
    13741 cccgctcaat ccgagtactc aaacgactcg tatccgctgt aatcaagaga aaatgttcat
    13801 aacctttttc gatacaggac tgggtcatgt cataaacggc atcatagtta ttggttttaa
    13861 cccagctagt ccggtgttca tagagctgac tatcaaaaaa gaccattttc ttctttttct
    13921 catcgatgat acgagaatat tttcggaaat tagaggtcgg ctgaataata aagccgtcta
    13981 ctcccaagag aagcatgctt tcaatatacc ggtcctcact ctcttggctg taattactat
    14041 ttcctatcat tacctggtag ccattctggc tggcgatatc ctcaattccc ttaacaattt
    14101 ggtttgagaa actgttggta atatcaccga tcaaaacacc gattaatttt gttcgtttgg
    14161 agtttaagct acgcgcaaca atgctcggtt tgtaatttgt ttcatgaata actttttcaa
    14221 tcttttcacg tgtctcttgg gacatttttt catatttccc gtttaggtaa aatgacacgg
    14281 ttgttttcga ggtctgagcc atttccgcaa tgtcttttat ggtcagtttc ttctccaatc
    14341 taaaacacct cctactaata cttattataa catattcact attcaaaatg cctatttcta
    14401 gcactgcaag cgaatcattc tctcatttat tttatcatat actagacatt ttccacgcat
    14461 ttttgttccg tcaacgaggc acaatttttc acctacacca atatcctcgc ttaataacag
    14521 aatcagcttg tctgtttcgt catttttcac ttcaaaagcc agagcatttt ccacttcacg
    14581 atcatctgtc tggtagacag aatgacggat aatttcaaaa ctctcatgcg caatgatggt
    14641 ataatccagc atctgattct caaagaattg gcgcttggtg agtttgctac ttctttcaag
    14701 ctcattgtat ttaggagaaa tgatggtatc ttccaaatca aaatcaactt cactccatag
    14761 tctcaactga ttgattttcc catcttgata ggtcacatcc ttgtcaagga taaactgagt
    14821 caacgcctca tgctgacctt gacacctgat gtcatctacc aagagccaga catcctctac
    14881 caacatgagg atttttctct tgtgaagata aggcaaatca ggttctgctg accaataagc
    14941 cccctcaata taatgcactc cctccctttc tttatggtga caaaacaggg agtgaggata
    15001 gtattcatat tcccaggatc ccgtgattct ttccggagct ttcccatcta caatgcaggt
    15061 cgaatgactc caagcactct ttaagagata acgttcatat atctcccgat aagaataacg
    15121 cccagcatct atgaaaatag gttggccttg atactgtaag caaaaactat tctcgtcact
    15181 atggctatgg gcacttccta gcggaccatt tttgaaaaat agataacgat gttcatcctt
    15241 aatgcagaca tgtccagagt cttcaaagat catggactta ggctgccaag ctctcctttc
    15301 aaattcctgc agtcgcttga ccttttctcg ccccaggaac aagaggctaa gcaaatcgac
    15361 tttaacatcc agaccgttaa gaaggtcttc cttgttcaaa accacagcag acaggctcaa
    15421 aatttctgtc gtttctgtag aatcgctatc accaaaagcc aaagttcgtc catctaagcc
    15481 tgtcatcatt tgaatatagg tcgccatctt ttccagcaac tctcggtaac tatcttgcaa
    15541 gtctggaagc aagagacaca aatccagcaa ggctttataa acctctacat gatagagaat
    15601 cgactgttca aactggcttc catctcctaa aatctgtgtc tcaatttgct gtttcaactc
    15661 ctctgaagca aaatggtaag cttcttctag gtccatctta tctgaaaaga aataatagat
    15721 agcaagcatc ggaattgttt gtaaaatccc ccagttacta agggtgtact tggcgcgata
    15781 gtggcttttc ataaagtcaa tctgcttttc tagactgacc aaaattttct ctagttcttt
    15841 ctcctctagc aagtcaaatt tcaagaggag caagagtagt ttcaaccaag taaaggaacg
    15901 aatacccgta tccaaggttc tagtcatcaa ggattgagga gaaaattctc tcacctgctc
    15961 aatccaatca aatagaaaga acttgcactt ttggatatag cccttatctc cttctaccag
    16021 ataccctatc ataaactgca agagatattc ttgtcgattg agcatataag accattctgg
    16081 atcatcttca aatacttgat cccataccat cggctggatt tgatggattt ttgaacaagg
    16141 ctccatatcc caaggactat caaacataaa acgattgtct atcaagcgtt caagggaact
    16201 cttgactttc tcatagtctt ttgaacagtg ggacaagata taatcacgac attggtttcc
    16261 atcgactctt tcaaaaaatt gtcttctttc ttctttcatt atctattacc agaaaaagaa
    16321 ctacttaaaa agcagttctt ttgtctttcc cattacactt tccttttcta catagatgac
    16381 cacacctttt gcaatctgca aggagaccaa gtcatcttgg atagaaatga tttttccatg
    16441 aattccagac aataacaaca cttcatcacc agatgttaaa gaagctaaat actcttgtcg
    16501 ttgctccatc tgtttgcgaa gcaacttttg ctgacgaata gaatgaaagc ttgacagtaa
    16561 aaggggactc actgccaaga caatcactat tccataaaac aatgttgtat ccattaagct
    16621 ataatcttaa gccagcttcc gataattccg atgataactg ttaaaataac gagtttatat
    16681 gttgtccatt tcttttcttt gatcaagtag taaactaaaa gtgtaaatag ggctggtaga
    16741 agagctggag caaccttatc aagcattccc tgaatactta cgatactttg tttagcgtct
    16801 gctttaactt cccctgcagc aaaggtaatc ggcaccataa tcttaacaga tgtcgctgcc
    16861 aaaccagcaa ttacggttac accgataata ttggcaatac gagaaatcgt tgccatctgt
    16921 tcgcttagtt tatcaatcac agttgttcct agtttgtatc catacagacc agttgacaat
    16981 ttaatcgctg ttaaaatcgt attcatcgca aggaagaaca agattggacc gacaaccaag
    17041 ccttcttgag caaacgaagc tgcgatggtt gagaacaatg gagctaaaca gaattgagaa
    17101 agagaatccc caatacctgc caatggtccc atcaaggcca tcttgatgct acgtgtttct
    17161 tttgccggac ggccattttc caacattaca agatgcaagc tggtaataaa aggcaggaag
    17221 tgtgggttgg tattatagaa ttcacagttt tcttccaagg cttggtagaa accttcctga
    17281 tcctctccat agtgtttttt caaagcagga tacatcacat tggcatatcc caacccttga
    17341 tagttactat agttaaatcc attttgacaa aagaatgccc gcaaagacgt tttaagataa
    17401 tcacgttttg ttaatttgtt agatccagtc atcgtgtgct tcctcctcta ccacatgatc
    17461 cgctgttttt ggcttgttat aaaattcaat caaagcaaag atagtaccta caattgcaat
    17521 accaattgtt gggatgttta gataagctgc acaaacatat cccaacaaga caaagggaat
    17581 caactctttc ttagccatca ctgacaagat catcgcaaaa ccgatagctg ggagcatttt
    17641 accagcaact gtcaaacctg taagcaatac cggtggaatg tagtctacga gtttcaacaa
    17701 ggtatccatt gaaagggcac ccaagcaacc caaggtaaat ccaataaagg caaacaacca
    17761 aattgttgca tttagagtga acttgaattt cttcaaatta tggtttttca agtgcttcat
    17821 cgctgtttca ggcgcaccag cacgtacagt gtaggcgaaa gtttgtaaga attgaatcgc
    17881 cacagcaatc ggagtagaga gggcaagagc cgcttctgga ctgactttac cagcactagt
    17941 gatagccatc aaggtaccaa agataccagg tccgattggg tttggtggaa cagtacctcc
    18001 agcaccaaca ccgaatccca tataagccaa ttcaccaata gctcccattg caagagcagt
    18061 aggcagatca cctagaataa ttccgacacc aaatgacaga acaatgcatc tattggtgta
    18121 aattcctaac agcattccac taaaacagaa agctgtccat aatccaatta aaatcgcttg
    18181 aaatacatta atcgacataa cgatctcctc ttttaaatat agtccataat gttgacttga
    18241 acagctccat catttcctgt tggagttgtt ttcgtattaa atgttacttg atgagtttgg
    18301 ttcaattcct tgagggccgc cttgtcctct tcacccagga agatggagcg tgtcacttgc
    18361 tctttaccag tagcattgtg aatgttccca atattgattt ctttgatagg gacaccacct
    18421 tctaccaagg ttaaagcgtc cttcacatcc tttacaacga taaagatcgt ttgagcagga
    18481 ttagccttgt gaatgatatc aatcaccttt tgcaaaggga agaaacgcat ggcaactgag
    18541 tctggcacaa ctgttttcat cagagtttgt tgcatcttgt ccgtgcttac ttcgtcattg
    18601 gcaacaatga ccgtattaca acctaggtat tttacccaaa gttgtccttg tccatgaatc
    18661 aaccgttcat cgatacgggt cataataata tttggcattg tcatatttct cctcctacca
    18721 atataggttc cagtctttgt agaaacggat aagggcttct aggtaatagt agtcacccca
    18781 gatattgcct tcatccactc ctttacctga atgccatgag tacacaccgt ggaggagact
    18841 tgtcccacca ggggtaaatt gattatttgc ataatgttcg atcaaggaac gaagcatggc
    18901 atgcatagca tgtttataaa tatctttgtc agcatccacc tctgggagat gttttagcat
    18961 ttcatgaatc ccacagacgg cgatagctgt tgctgaagaa tctcgtgatt gatcactacc
    19021 atcattaaaa atcaaatccc aataggacac atgatctttt ggtagacgat tcaagaaata
    19081 attggtcaca cccttaaaca agtcaaagca ggactcgtct tttaagtgac gataagtcaa
    19141 aggaatacca taaactcccc atgactgacc acgtgcccag catgaatcat cactataccc
    19201 ttgtctcgtt acacctttaa agggttgacc tgtctcagga tcaaaataga aggtgtggaa
    19261 ggacgaagcg tcatcacgga ttacattatt agctgaagca tagaaatggc tttctgcaat
    19321 atcgtagtat ttttgatcgc ctgtttcttg ataagcaaag aataagagtt ggatattgag
    19381 caagcaatcg ataatcaaac ggtaatgctc tttcttgccc aagtctcccc aagcttgaat
    19441 aaaaccacct ttttcttgat agcgttcaat caacttatct gcagctttca aggctgcttc
    19501 tctagcctct ccatctccat ttatcttata ttcagccata caagacggtg tgtacaagaa
    19561 gccgagatca tggtgatcca attctactct cttattgaca cgatccagga aagaaagaac
    19621 atttttatga gcgatgtttt taaatgcatc ctgttgactg tattcataag ccaaccacag
    19681 ttctcctgtc cagaaaccat tggtccattc cgtgttatcc atgattggat agacattatc
    19741 aaaggtagct ggcgtcggga aatcttcctt gaaatagtca aggttgagtt ctaactgccg
    19801 aataacctta tcgattgcct ggccgacttc ttctttcgtc agaagtggta cttctaagaa
    19861 gcgctcaggc gattttattt tttcaatcgt aacctttttt atcattcttt taccctttaa
    19921 atacccgatt cgaaatcttc ttcctcttcc tctgcatccg ttgaaaacaa ttctttacca
    19981 tttacgactc cgccctgggc cgccactact gatttattaa caacctcatc aaagctatga
    20041 gccattctag caaagactgc ttccattaac atggctaagt tcaaacccga aagaacattc
    20101 attgttttgg ctggattttc tcccattatg gtagaagaaa ccttgaatgg cgatcctccc
    20161 aagagatcac ttaggattaa aacttcttct tcatttgaaa ttgcaagtaa gattttttgc
    20221 ttgagttcat ctgctgacat tccttccaca aagtcaattg cctccacatt ttcttgattg
    20281 cctgcaatca attgtaaaga actataaatc cctgtagcaa aatgtccatg ccctacaagt
    20341 acaattttca tcttttctcc tttcttgttt aggtttaccg gtttacttta tattccccat
    20401 tgtaatcctt tatttttatc ttgtcaatag tttttttaaa aaaaatatta gcgctttcat
    20461 tatcttttta atcattttaa tagacagaaa tttcaaaata ttacattttt aaggaaaata
    20521 aatcttttta taaataaaaa tatttattta ttgacaaaac cggtttacta gaatataatt
    20581 tggttataga gaagtcttaa caaatttgaa aggaagtatc aaatgacaaa tacatcattc
    20641 tcaattgagc agttttcttt aaaaggaaaa attgctctca tcaccggcgc ttcttatgga
    20701 attggatttg ctattgccaa atcctacgct gaagccggcg ctactattgt ctttaacgat
    20761 atcaatcaag atctggtcaa taaagggatt gaagcttatc gtgaagttgg catcgaagcc
    20821 catggatatg tctgtgacgt gacagacgag gacggtatcc aagccatggt caagcaaatc
    20881 gaacaagagg ttggtgtcat tgacatcctc gttaataacg ctggtattat ccgccgagtt
    20941 ccaatgtgcg aaatgagcgc cgctgatttc cgtaaggtca tcgatattga cttaaacgca
    21001 ccatttatcg tttcaaaggc agttattcct tctatgataa agaaagggca tggaaagatt
    21061 atcaatattt gttcgatgat gagcgaactg ggacgtgaaa cagttagcgc ttatgctgct
    21121 gctaaagggg gcttgaaaat gttgacccgc aacattgcgt ctgaatacgg tggagccaat
    21181 atccaatgta acggaattgg accgggttat attgccactc ctcaaacagc acctcttcgt
    21241 gagttgcaag aagatggttc tcgccaccca tttgaccagt tcatcattgc aaaaacacct
    21301 gctgcacgtt ggggaaatcc tgaagatttg atgggccctg ctgtctttct cgctagtgat
    21361 gccagcaatt ttgtcaatgg ccacatccta tatgtagatg gcggtatctt agcctacatc
    21421 ggaaaacaac ctgagtaaaa atagaaagaa gatcttatga aaatcgcatt aatcaatgaa
    21481 aatagtcaag ctagcaagaa tcacattatt tacgatagtc taaaagaagc gacagataaa
    21541 aaaggctacc aattatttaa ctatggtatg cgtggagaag aaggagaaag tcaattaact
    21601 tatgtgcaga acggactaat ggctgccatc cttttaaata caaaggcagt tgactttgtt
    21661 gttaccggct gtggtacggg tgtaggggct atgcttgctt taaacagctt ccctggtgtt
    21721 gtctgtggtc tagcagtgga cccaactgac gcttaccttt attctcaaat caatggtggt
    21781 aacgccttgt ctatccctta tgccaaagga tttggctggg gggcagaact gaccctcaaa
    21841 ttgatgtttg aacgcttatt tgctgaagaa atgggcggtg gctacccaag agaacgtgta
    21901 atccctgaac aacgcaacgc tcgtatctta aacgaggtga aacaaatcac ccacaatgat
    21961 ttgatgacca tccttaaaac aatcgaccaa gacttcctca aagacaccat ctctggcaaa
    22021 tacttccaag aatacttctt tgaaaactgc caagatgatg aagtcgctgc ttatttgaaa
    22081 gaagtattag ccaagtaaag ctattctaaa ccagaaagga actaatggat gacgaaaata
    22141 ttactgtttg gcgaaccatt aattcgaatc tcaccattag atgccaccag tatcggcgat
    22201 catgttgcca gttcgactta ttttggcgga tcagaaatta acatcgcttg taatttgcaa
    22261 gccctgggta tctcaacgaa agtctttacc gcactccctg ccaacgagat tggagatcgt
    22321 tttctcacat tcttgaaaca gcaccaaatc gataccagtt caatctgtcg gcttggcgat
    22381 cgaatcggcc tctactattt ggagaacggc tttggttgtc gtcaaagtga agttttctac
    22441 gatcgtaagc atacgagtat cagccagatt cggccaaaca tgctagatat ggattctctc
    22501 tttcagggga ttagccattt tcattttagt ggaatcacca tagctatcgg tcaagaggtc
    22561 cgtgcgatcc ttctcctact cttggaagaa gccaagcgcc gaggaattgt cgtttcaatg
    22621 gatctcaatc tgagaacaaa gatgatttca gtcctagaag ccaagtatga attttctaag
    22681 tttgcacgtt ttactgacta ttgcttcggt attgatcctc tcatgattga tgaccaaaat
    22741 ctagagatgt ttccaagaga cagtgctagc ctagaagagg tggaaaatcg catgcgactt
    22801 ttaaaagaag cctatggttt caaggccatt ttccataccc tccgatctag tgatgagcaa
    22861 gacaaaaatg tctatcaagc ctatgctctg gaagaacgat ttgaagagtc tgtccaacta
    22921 aaaactgcag tctatcaacg aattggtagc ggggatgcct ttatatctgg tgccctttac
    22981 caactactcc atcattcctc cctaaaaact accattgact ttgcagttgc gagcgcaact
    23041 ctcaaatgca ctcttccagg agaccatctc tccacttccg caactagtat tgaaaattta
    23101 ctggcaaatg cacaagatat cattcgttag gagaattaca tgaccaaatc agatacgatt
    23161 attgaactaa aaaaacagaa aattgtcgct gtcattcgag gaaatacaaa ggaagaagga
    23221 ctacaagcct cgattgcttg tatcaagggc ggtatcaaag ctattgaaat cgcctatacc
    23281 aatcagtatg caggacaaat catcaaggaa cttgtagact tgtatcagga cgatcagagt
    23341 gtttgtatcg gtgcaggtac tgtgcttgat gccgtaactg ctagagatgc cattctagct
    23401 ggagcaaatt acgttgtttc tccatctttc catgctgaaa ctgcgaaaat gtgcaatctc
    23461 tacagcacac cgtacattcc aggctgtatt accctcacag agatcacgac tgcacttgaa
    23521 gccggtagtg aaatcatcaa actcttccca ggtagtactc tcagtccagc atatatctct
    23581 gcagtcaagg caccgatccc acaagtttcc gtaatggtaa ccggaggagt cggcctaaac
    23641 aacatccctc aatggttcgc tgctggtgca gatgccgttg gaattggtgg cgaactcaat
    23701 aaactcgctt cccaaggcaa ctttgaccgc atcagcgaga ttgcccaaca gtatgttaca
    23761 ctcagataaa atcataacca cccgtcaaac gggtggttta tcccagagct ataagcccaa
    23821 atcatcagcc aagcgcctaa agacgctggc tttcacgttg ttcaagcctt attgctcttg
    23881 actcgtcact tgcctcttta agagactttg gtattactta ccactatccc taaagggatc
    23941 ctcatattct tttacactca atttatctag tgctatagta gattgaaact ggaatagtac
    24001 acatctactt ctaaaacatt gttaaaaatc gatttgactg tcctgatcga tttgttctgt
    24061 tcttatttca ttttactata tatcatgctt tactcgttct caaattttca tactcgtgaa
    24121 gaaatcatcc actggataat ttctttaatc ttgactatat ttcttaattg tggctttatt
    24181 aagccctact ggacttacat aataaccttc cgcccagaaa tgccgattcc caaacttgta
    24241 cttgagattg gcgtgtttgt caaacatcat gagtgcactt ttgcctttta aataccccat
    24301 aaaacttgaa acacttagcc tcgacggaat actgactaac atgtgtacat ggtctggcat
    24361 taagtgaccc tcgatcattt caacaccttt ataactacac aagcgatgaa atatttcgcc
    24421 taaactactt ctatattgat tatagatgac ttttcgtcta tacttagggg tgaacacaat
    24481 gtgatagaac acctccactt tgtgtgagat aaactatgag ccttttgtgc catatttttt
    24541 ctcctttcgc tttacaagtg gattgaacac ctttattgta tcgcgtttgg agtttttttg
    24601 gtataacctt cgacgcgcac ccgtatagcg ggtggttgtt ttgtctcgca cctcacggag
    24661 cgagacggac taatatagtg gagtgaaata ggatacgaac aaattgatta ggaaaatcaa
    24721 atgaatttat agaaatcttt tagcagttat gatgtcctat tctagtttca aaacgctata
    24781 gtcacataat gaagtaaaaa ggataagtat caacttatcc ttttttaaaa gaaaaatccg
    24841 aagatatttg gccttcttcg gattttttct attttccaca gtttcatgta attcatctag
    24901 atgatgaaca aattagttgt tctttcctct acggaataga taaaacgccc caagtagcaa
    24961 gaaccctaga cttgccaaga ttgactgacc ttctcctgtc tgagggagat tcttttgatc
    25021 cgaatggttc ttttcctctt cagatttttc cttttctttt gaattctgta cttgtggctg
    25081 agctgcttgc tctagctttt taaagacttc ctgatctgga gctgattcct gggtttcagg
    25141 attatagtag gcaatcttat attcatcccc ttcttttcga atggtataga ctccacgttt
    25201 caaaacttgg aattggttgg aaatagtaga gacagaatca tcatatttca caatgcccca
    25261 aactccttgt ttggcatcat aaacagactg aagggtttcg ttattttcga tgaggctact
    25321 ttctaactct tttatcattt gattgaaggt ggcacgatcc acgttaggaa tgagcatata
    25381 gccataagaa tctccatttt gcttatgagc ctgactaatc gtaagaaatt cattttcaac
    25441 ttccttgtct gactgtcctt cattgatatc cttccaggct cccttttgca aagccttact
    25501 catgctgatt gaactcttct taaagaaaaa gtaaccaata ttctttttcg aatcggacga
    25561 ttctaaaaag acactttggg tttcaggata atccttttct tgttctgtaa gggaggcttc
    25621 tttatcattg acatagactt tatatggatt acttgattcc agttttctct ggtcgattgt
    25681 agttgcagca gtatctgttg aagtgttttg gatattgctt cctaaaaagg caatcttatc
    25741 ctttagcata aaccagctct tatgagcagt caatgtttga ttccagttgg tgaaatccat
    25801 ggttgctgtc gcattggcat catctagttt gctcgttcca acgaaagcag acggtaaaac
    25861 tttacctgta tcgctatccg ctctcttagc atccgtctct gttgtaccag gcatcttata
    25921 tggattaact gttggccagt agccatcgct atagtgactc aaatcgccat tgtaaagata
    25981 gaacatccca tcactcgtat accaaccacg tttattttcc ttgttcatgt gttcgtaatt
    26041 caaggtacga ctggaaaaga gtgacaagcc aaatccaaac cctttctctg cattgtacat
    26101 ggctgtttta tccatcttgt taaaggcaga taggtaactt gttcttggaa cacttgcgac
    26161 tcctgcatca cttaacaagg attgcatcaa actgatatcc ttataagtct tcaaattctt
    26221 aaagacatca taataactat ccgattgaac aatggtcttc acaagactct gcaaacgttg
    26281 tttggtttct ccttcagaca tatccgctat tcggtgaatc cctcttagta cttctactgc
    26341 ggccacgtgc ccctcgctat ttgcacgact gatcgagcgt ccacgactca tatccatcag
    26401 ctctccattc accagcaaag gagcaaacga tttatcaatc cagtggtaca tggtttgcat
    26461 tttatcttta tcgattggat tcttggtctt ttgaatgact ggcaacagtt gagacaggcc
    26521 atcaatcaaa acattcccat aagcacccgt ataggcaaca ttggtgtggt cgatatagga
    26581 tccatcttga taaaaacctt caccttggtc taccaacttg aacacttgct caatcgagcg
    26641 aatggtagaa gaaatttctt gatcatcctt acgcagtaaa ccagctatta cttttactct
    26701 tcccatatca actaagtttc cacctagagc cttaaatggg ttatcagtcg tctttcggaa
    26761 atgttcggga tctggtacaa atttttcaat cacatctgta tattttttaa tttcctcatc
    26821 agagaagtat tctttcatca gagacaaggt attgttgatg gcacgaggtg taccgatttc
    26881 ataatcccac cagttcccaa caatgctctt ttcacgattg tagacatgtt tatgcatcca
    26941 ttccatggaa tccctgactg ttcgaacgac agtttcatct tgataataac gagaagaagg
    27001 attggtcact tgcttggcca tctcctccaa tttccgataa gtggcagtca gatttgcaga
    27061 cattttataa tttgaaaatt tttcccacaa ataggtgcgg tccgcctgac ttgaaatact
    27121 agataggcta tcagctacct ttccttccaa ttcctggttt aatttggcca tctgttcatt
    27181 tttagaatca tagtattgat tcccagcgat gatgccattc cagtcatcca aacgggctgt
    27241 gtatgcatcc ttaacagagg ctagaatctt caaaggaatc tttttcactt ccttgccatc
    27301 tttactgaca atgacattgg ttgtcccttc cttaagaggt tctaaaattc catttttgac
    27361 tgaagcaacg tcaggatttt ctaccttata agtatagtcc gcaagagaaa aaacatgttt
    27421 ttttccaatt ggtaaatcaa tcttttcctc aagctgttta tctgtttgag aatcctcaga
    27481 aagctgggct gctacctcta ccagctcaat atccttaaag gaaacagtcc cagttcctgt
    27541 ttcatagaat aactccagct tgattttatc aacatctaaa gtcgggctat agtctgcttc
    27601 aatggtctgc cagtcctttg ttcctgacgt cgttgcagaa ttccacaatc gcttgtcctt
    27661 accactttcc tcaatgatac gaaccttggc aatcccgact ttattatctg ttttaatctt
    27721 gaaacgcagt ttatactttt tcttagcttc aataggaacc atacggtgaa ccgctgccct
    27781 taatttctca gggcttgaga tagtgatagc cccatcctta gcctcaatga ctcgagttga
    27841 ggcatctgca gaactattct tctggtctac ccaagctgac cacccctgag ctttgcttcc
    27901 tgtccacgga ctgcttccgt cctccgtctg accaaaatca ccattttcaa ctaaattttt
    27961 tgtatccctt tgctgatact gaacttcctt ctggctttgc tgaatggtat tcgtagtcgt
    28021 ttcttccgct ccaactgtca tataatggtt taataaaaat cctgataaaa caagtgaaga
    28081 caaactcaca atgagcttct ttgtttttgt ttgcatgtat acactccaat aaacatattg
    28141 taaaatcaat aggaactaaa tctcaaatta gagatttata gcaacaaagt aaaccggttt
    28201 aattaaatca taccattttt aaagttattt gtaaacggtt tctatcatat tgagggctta
    28261 ttcttcaaca atatcttcca tccgactcga cgaaaaaagt aaaaactgtt acaatgtaga
    28321 aaaagaaaag aggccctcat gacttcactt tatgattttt ccgttttgaa ccaaaacaac
    28381 caagcaactc ccttggatag ctatcgtggc aaagttctct tgattgtcaa cactgctact
    28441 ggatgtggtt taacgcccca gtaccaggga cttcaagaac tctatgaacg ctatcaagat
    28501 cagggcttcg aaatattgga tttcccttgc aatcagttta tgggacaagc acccggcagc
    28561 gcagaggaaa tcaacgcctt ctgtagccta cattttcaaa ccaccttccc acgttttgcc
    28621 aagattaagg tcaacggtaa ggaagcagac cctctctatg tctggttaaa agaccagaaa
    28681 tccggcccac taggaaaacg agtcgaatgg aatttcgcta agtttctcat cggtcgagat
    28741 gggcaagtct ttgaacgctt ttcttcaaaa acagacccaa aacaaattga agaggcgata
    28801 caaactctac tataattcac aatctcacta tgattaggtt tcctttaacc tgatgaatag
    28861 tgagattttt tgattggctt tgacttaaat agaaaaacac cccatgatat gaaacatgaa
    28921 gtgttgtaaa gtctatgttg taggtgctta tttcacattt tcaatgtgac cagtgataac
    28981 gaataccata cagaatcttc atatacacta aacaaatgac tttctaatta tatcaattag
    29041 ttttggctag taaatatcat ttccaacaaa cgccctctca attccttatc ctgatgatgc
    29101 aagatattca ttaagtcatg agagtttttc gcattgatga attgatttaa caatctatct
    29161 tttaattcat atggaagaga agctgtcttt agtagtctaa aaacttcgtc atttaaagat
    29221 gtccttttat tatctttcca ttcaaattta gctgtatcat tcttatttgg caattcaatt
    29281 atagacacat tcgttccttt aaaatgaatt ctatgttttc tattgcttgg aacgatacta
    29341 gaatctcctt gtaatgctaa ctctaccatt cccatttccc aatcgattga taatcttgtt
    29401 ttatatcttt gaccattttg atcttcaagc atttcaaaag aatgttgttt tcctgggaat
    29461 acataccaat ctacaacttc aggtaaatca acacccatac ctatctcaga accaaccaag
    29521 ggaatgattg caccactttt tgcaaacaca ggcgtagtcg agatgtccct ataaacactt
    29581 aacttcacac cacctgtgta ttttttatct gaaaaaaagt cataccattc accttcaggg
    29641 aaccatacat ctacttttgc agattggaat gtcaaatcca tcttttctac aatgggagcc
    29701 accatcagtt ctgttccaaa aaagtattgg tttggaacat tatagctctc atcattctct
    29761 ggatagaaat aatagattgg actgattaat ggggcacctt cctcatgtgt ctttacattc
    29821 atggtatata gatagggaat catctgatgt ctcaaacgaa ggtatttctt cataatctta
    29881 gatgttgttt ctgaaaaaaa ccaaggttct ttactattaa aaggacttct agaactatgt
    29941 aatcgagtaa tcggactaaa aacaccaaac tgtagccatc tagtttgtag ctcttcgtca
    30001 taatccccca gcatgtgccc accgatatca tggctccacc aactataacc gatattagat
    30061 gctgtcgctg taaaataagg ttgaaatctt aaggaattcc aactaataat agtgtcccct
    30121 gaaaaaccaa cagggtagcg gtggctacca ggacctgcat atcttgataa aatcaaacca
    30181 ccttctgcat ttttacaact atcctgataa tgataatggt ttaaaagcca tagtggatcc
    30241 aatatgcctt gagtcccttg ttgccagtca atccaccaaa aatctactcc ctgcttttct
    30301 agctcataat gaacatcttt aaagtaggct tccctaaaag agggattaaa aaaatcaaaa
    30361 atggcaggtt cttctagttc tacatttaac cctaatcgtt tggcgacttg aggataagct
    30421 tcttcataag cccgtatacc atcagcagga tggacattta aagagagttt taactttcta
    30481 tcatgaagtt gttgcaataa ctgttctgga ttaggtatta agtttttatt ccaactatat
    30541 cctgtccagc cacttccaaa acgagctgga atgtcagtta tatgccaatc catatctaac
    30601 acaccgatag ataatggaat tttctctgtt tcaaatctgt ctattaaatc caagtattca
    30661 tccgacgtat aaggccaata tctactccac caattcccta aagcatatct tggcaacaag
    30721 ggtgttgaac cagtcaaatg gtaaaagtct ctgattgctc ctctataatc atgcccatag
    30781 gcaaagaaat agaggtcaat ttgattttct ctctcaatat aaccagattg ttcatcccaa
    30841 ataaatcctt gagaatcatc caataaggct ataccatttc ggctaataat tccatcttct
    30901 aacgagattg ctccatctgc cttatccaga gtccgagctg ttccttttaa cgtttcaata
    30961 gattcaccaa aataccagcg actaccatat acggcaaaat ttccttttaa ttctataaat
    31021 aaattttcgg cgttaaattt tcctttatta aagtgcagat gaaaatagtc cgtcataata
    31081 tctagtacat ttgatgtctc gatataatct aacgaatttt ggccaaaatc tctattatag
    31141 ataagttgtg tcgttctatc ctcaaaattt ccagttcgag agtattctaa ccttactagc
    31201 ttgtctgtta atacagagat tcgataaaac tctcccttaa aaattttcaa tttgttttcc
    31261 tccttttatg gtagcataaa aacagaacgc accatttttg atgcgttttt cattattctg
    31321 aatgcaatgt tctatctgtt atatctatga caaataatag tcaattgaaa aaatgtagtg
    31381 gacaaaatat cttttaacaa accaagagtt tattaaagag ttatcacttt tcaacttttc
    31441 taagcttatg cagttgtgaa acaaactact tttaaactat taactaagat aggattgata
    31501 aataatttca aactcttact agcaatcata cgatattcaa gctcacgtgc ttttttcctt
    31561 cctgcttatt tcttagaact gaagaacccg gatcggtata taaattatcc ggatcaacat
    31621 agtcataaga ttcataacag ttgcgcttca ttaagtcatc cccagagcaa gagcttcatc
    31681 tcgtaatttt tcaacatcac taaccgtagg tcgccatcct tcaatcatat ttgtacttaa
    31741 agcataccaa acactcttaa aaacggatcg gttttcaaaa gctattccca tgattgtcat
    31801 cttttcttta tctatatcta aggacatatg ctacctcctt tagatacatt ataccatgtt
    31861 tctctgtagc ttttaaaaat tttattttgt ttgtcatatc taagttttca gcacgcttat
    31921 cctattttat aagcctcaaa cccaaatata aaacgcatta accatctgat aatatgcgtt
    31981 ttattgtgga aacatttccc attttctcta tttctaatga cttacttcaa cttctgactt
    32041 catggaaaaa acaacaaaaa tatgaactgg caaagtttgg tatcatcagt aatccagaac
    32101 aattcatctt tacttacata gataccaaag gcaatatcaa taaaccttta cattctgact
    32161 atctcaataa taagatgaaa actatcagaa aacgacaccc agagcttaca cacgctacgc
    32221 cacacaaact acgtcatacc ggagcaacgc tcgctaaaca agcaggaatg agcttagaag
    32281 ccatttctga agctctaata catagcgaca caggtacaac acagatttat gtcaatactt
    32341 ctaatgtagt ccctatggcc gtcggtgaat ttgccttaca gtctctaaaa caataaggtg
    32401 aaaataaggt aaactttgag gtgaactttt tcaaaaaaca taaaaaaagc acccatgagg
    32461 taaactcttg agtgctttga aacgttgata taatcgtatt gattaacgtt ttgaggcaac
    32521 tgaccttgtc aggttgcagc cacatttgta agcgactaaa gtcgcaacaa ctgtgtcaat
    32581 tgcaccaatt tagtaagaaa gtataaaaaa gaacaccccg aaaggtgctc tgtataagta
    32641 tagtaattct ttcgaattaa cgtttactaa attgtgatgc tttacgagct ttcttaagac
    32701 ctggtttctt acgttcaact ttacgtgagt cacgtgtaag aagtcctgcg cgtttcaatg
    32761 aatcgcggaa gtctgggtct acttgaagaa gggcacgagc gataccgtga cggatagctc
    32821 ctgattgacc agcgtatcca ccacctataa cgttaacgaa aacgtcgtat gaacctacag
    32881 ttgaagtaac tgcgaatggt tggttgatga caagacgaag gtcagcgtgt gggatgtact
    32941 cttcaacatc ttttttgtta acagtgattt taccagttcc tggaacaagg cgaacgcgtg
    33001 caacagcgtt tttacgacgt ccagtacctg catattgtgc ttgtgacata ctttattgtt
    33061 cctttcctta gataagtcct gaaatgtcaa gaacttctgg ttgttgtgca gcgtgagtgt
    33121 gctcagctcc aacaaatact ttcaacttca taccttgagc gcgtccaagt gtattgtgtg
    33181 gaagcatacc tttaactgat ttctcaatca aacgtactgc atttttagaa cgaagttcac
    33241 ctgcagagat ttgtttcaat ccacctgggt ggtttgagtg agtgtagtag attttatcag
    33301 ttgctttttt accagtcaat ttaacttttt cagcattgat aacaatcacg aagtcacctg
    33361 tatcagtgtg tggtgtaaat gttggtttgt tttttccgcg aagtacgcta gcaactactg
    33421 cagaaagacg tccaagtggt acatcagttg cgtcaactac gtaccattta cgttcaactt
    33481 ggcctggttt agccataaat gttgttttgt tcatgatttc tcctatatat agttcgattt
    33541 ttgtttacgg tgatgggtgt tccttcccat cgaaaagtat ttggaaggtt ccggggcctt
    33601 tcaaatgggg taaacaatac cgcctactat cataccaaat tttaccccta aaagtcaata
    33661 gatatgaaaa atatttttcg gtaacttctc aaagtaactg aaagttatat aatcaagtta
    33721 atttgggaat ttacctatta acttcggtag atttttggga atttttttcc ttctttttcc
    33781 ctgtagttaa aatccttttc aaaaaatcac cttttcttga tttttaatcc tatttgctgt
    33841 atgataaggg aaaagaaagg ggacagagat atggctttta ccaataccca catgcggtct
    33901 gctagttttg gcattgttac cagcttgccc gatgacatca ttgactcttt ttggtatatc
    33961 atcgatcatt tcttaaaaaa tgtctttgaa ttggaagaag aactcgagtt tcaattgctt
    34021 aataaccaag gaaagattac cttccacttt tcaagtcaac acctccctac agccattgat
    34081 tttgacttta accatccttt cgaccctcgt tatcccccaa gagtactggt tttagacatg
    34141 gacggtagag aaactatcct cctcccagaa gaaaatgacc tattttaaaa actctagcct
    34201 tcagttgcaa gtaactgaaa actagagttt ttctattttt tcaaagcatc atacaagtta
    34261 cggatcggtt gttttaatat cggatggata aaatgaggcg caatttcctg taaggactca
    34321 aggacaaaaa ggcgttccgc tatgtaagga tgaggcaata tgaggtcgtc tgtataaagg
    34381 atctggtcct ccacaaagag caagtccaaa tcaatcaaac gaggtcccca atgcacttct
    34441 ctcacccgtc ccagctctga ctcaatggct aacaaggttt ctaacaagtc ttgtgctggt
    34501 agccaggttt ccacctcaac cacttgattg gcaaagctat cctgctccac tccaccccaa
    34561 ggctccgtcg ctaagacact ggactctttg agaatataga tgccacgagc tcgcagtttg
    34621 tcaatggctt gcttcaagtt tgcttgttta tctcccatat tgcttcctag ggcgataaag
    34681 gctcgttgct tgcggcgatg aatggttacc gagcaagtat ctagtgacaa atgcaccggt
    34741 gcccaaggtt ttttcagttc caacttcatt tcttggacaa gaggataaga ctcaaaggta
    34801 cgttccacca gtttataggc taccgtttca atcaaatctt cactcgtttc ctgaaaccaa
    34861 gtcgtccact gctgacacaa ttctccgtaa tggacagagg ctgttaaatc caagtctgta
    34921 gctgccttgg tcatatcata ggataggatg gctgaaacga caaatttctg ccccaattcc
    34981 ttctcactag gaaaaagacc atgataggca aaaatttcca aatccttaat ctgcagttga
    35041 tccataatga ttcctttcta gaaaaatccg cccaaagcgg attcttttta tactcaatga
    35101 aaatcaaagt gcaaactagg aagctagccg caggctgctc aaaacactgt tttgaggttg
    35161 cagatggaag ctgacgtggt ttgaatttga ttttcaaaga gtattatagt cccattaaac
    35221 gataagcctg atctcggagg tccttatctg tttcaaatag accacgagct actgtcgtca
    35281 aggttgcagt gcctggtttt ctgacaccac gcatgctcat acacatatgt tccgcctcaa
    35341 tgacaacaaa ggctccttta gcacctagat actccatcaa ggcatcggcc acttcgatat
    35401 tcaaacgttc ttgaatttgt ggttttttcg aataaacttc aaccgtacgg gctagcttag
    35461 acaaacctgc cacacgacca tctggaatat aggcaatatg tgctctccca taaaatggca
    35521 gaaagtggtg ttcacacatg gtatggaaaa agatatcctt ttctaccacc atattatcgt
    35581 caataatctc aaaagatttt gacaaatgtt cctccgctgt ttgaccaagc cctgaaaaaa
    35641 tctcttggta catacgagcc acacgagcag gtgtttcctg caagccctcg cggttagcgt
    35701 cctctccgac ggcctcgata atcattttta cagctgcttc aatcttttgt gtatccattt
    35761 tcgttgttcc tctccatcag ataggctctc acttggctca agaaatacaa ggaacctgtg
    35821 acaatcctaa ctgtttgttt ctcttctttt ttatctgtca atttctgctc tagaaaatcc
    35881 tgccaaccct gatagctgag atttctagac ttggctgcct ctttcagcac gttttcatca
    35941 gtcgcccgac tatcgtcaaa atgtgtcagg gtaagctcgg tatctgggat ttgctccaac
    36001 aaatccaaca tatcctccaa ggccttggtt ttgatgcaag taaagaggat ttccttacga
    36061 taatccgcaa agcgttcttg caaggttgct aataaagcct tgatagcatg ggaattgtgg
    36121 gctccatcca aaatcatcaa gggatctctt gacacgattt ccaaacgccc tggccaactt
    36181 gtttcttcca aagcttgagc aagcaagtga ttgcttgcta gttctcgacc atcttcttga
    36241 caaaaagtat caagtaaagc tatggccatc ccagcattct ctatctggtg caaaccaagc
    36301 aggccagtct ggaagcgacc ttgtctgaca acacttgtat agtcaaagac ttcgcctgta
    36361 accacactct tttgatggct gacctgataa tctatcccgt aggcaagtct cggcgcatct
    36421 ttcccttccg caatgcggtc aatcacagcc aaggcttctg gagcgatacg acctgtcacc
    36481 aagggaattc cttgtttgat aataccagct ttctgctctg ctatggcttc caaggtgtca
    36541 ccaagtaggg ctacatggtc cagtccaata gtcgtaatgc ctgttaaaat gggctggcag
    36601 acattggtac tatccaagag tccacccata cccacttcca tgatagccac atctatttgc
    36661 tctgaggcaa agtaatcata ggctatagct gtaattattt caaactcagt tgtcccctgc
    36721 aaattggtag ccgattcccc ttccagcaaa gactgatagt ctcccatgag ggcttctagt
    36781 ctagcctctg ggatagattc cccattgatg ctaatctggt ctgtataatg aatgagatag
    36841 ggcgagctga acaccccaac tctcagccct agcttttcta gcatcttttt caaaaaagca
    36901 atggtcgaac ccttgccatt ggtccctccg atatggatga ccttgagttt gagatgggga
    36961 ttgccacgca aagctaatag ttcctccatt cgttccaagc caaaatgcgg ttggtccgtc
    37021 cggtagttag caatccactg attgttttga atttctttca tcttatttat attgttttaa
    37081 atctaaatct tccgcttcat cagccagacg aatggcggag gcaatttcaa ctgccatcct
    37141 gtgactaact acatcatgca cgcgcaccac ttccacaccc tgtctcgcag cgatactggt
    37201 tacatgagcc gaagccgtat ctcgattgcg gaaaccaagt tctgtctcag gattgacttc
    37261 aaaaccattt tcttcaagaa tattgatgac aaaccgcttg cgcgacactc cgagaaagat
    37321 tggatagcct ttctgatgta gtttatccag atcccgtaaa agaagcagat tttctttctt
    37381 ggtcagacca aagccaattc ctggatccag caggatgttt tcttgagcaa tcccagcttc
    37441 ctctgctctc gctagtgctc gttcaaaaaa agtctccatc aactcttcga ttggcaattt
    37501 ttcaaagtca gctaactctt cctctgtaaa agcttgtcca aaaccaaaat gaggaaatat
    37561 gagcgagcta ggatgctgag gtcgcgccat gactggatta aacataatga ctactttcgc
    37621 tccagcattt gcaaccacat gggccatttt ttcatcaccc atgagaccag tgatatcatt
    37681 gactagattg gcaccagcag ccaaagcagc ctctgctacc tgactcttcc aagtatcaat
    37741 agagatgagg acatcacttt ccttgcgaat cgctttaatc actggaacaa cacgctggat
    37801 ttcctcttct atctcaacat agctactact tcccggccga gtcgattctc cgccgatatc
    37861 gagcatacta gctccttctg ctatcaattt acgagcctgc tgaagtgcct gctcaagagc
    37921 aaaaaattga ccaccatccg aaaaggagtc tggggttaca ttgatgattc cgcaaatagc
    37981 tgtctttgca tgattggctt tacttgacat atcggtcact ccctcaaggc tttttaccat
    38041 attatctctc tattttacca taaaaagaaa aagatggaca cgattgcatt catctttttc
    38101 ccagtagaag caagcaattg tcaaaaatct taaacagaaa tccctaatgt ccgactcatg
    38161 atcaccacaa gtgccaataa acagaaggct accccattaa caatcatgtg aagcaagata
    38221 gacatttcca aacgttgtgt cttgtaagct gtccaagata gaacgattga catacctcca
    38281 taaatcaata aagaaggtaa attacttggt tgatgcaata aagcaaacac aatcgtacca
    38341 accacaaatc ccaagttctc ttttcctcgg aaaatctttt taggaacaat cccacggcac
    38401 aagatttcct cacaaattgg agcaagcaag gccaacaaga agaaactgga aatcagagaa
    38461 ctattctgaa ccatgtcgtt aatctgagac tgattccctg ttgtcgtctc atttgacagt
    38521 tgtaacaaga tagaaccaag tatatttgac ccgataataa ctaaataact caagcccaag
    38581 cgtgccaaat ccttagctct aaaaaaagaa aaattaaaac tagctaattg cgttttacga
    38641 gctccaaaaa taaatagtgc caaaactaca atagaaatgc ccgcaactat cagtcctgac
    38701 tgtaacagtg gtactgcatt taaagttaaa atagcagtaa cccctatagg aatctgatat
    38761 aaaattgtcg ccagaaaaaa gattaacagc caacctgcac gattcaataa ttctttccac
    38821 atatttttct ctttcatcac ctatctcctt tgtattaaaa aagggggaaa atccccctgg
    38881 gttatcctat tataaggcca tgctgatgta gttaaggata aacaaggcat ccaaaatcca
    38941 aatcatgaca tgaacatctt tagcttgacc tttaacaagc ttagtcaaag tgtaagtcaa
    39001 gaaaccaact gcaatccctt gagtgataga gtagctgaat cccataaaga tagatgtgaa
    39061 gaaagcagga accgcttcag atatatcatc ccaatggata tttttcaagc tagccaacat
    39121 cataatccca acgataatca agattggagc tgtagcggct gttggtacaa tcgctagaag
    39181 tgggctaaaa aagcttgaga tcgcaaaaca gattgccacg accaaggctg tcaaaccagt
    39241 acgtccacct gcaccgatac cagcagcaga ctcgacataa gtcgttacgt tcgaagtacc
    39301 agcgatggca ccaattgaag taccaatcaa gtcagagtaa agagccttat ccaacttagc
    39361 tgattggtga ttttcaccat ttgtcgctac gataccaact ttttcacctg taccaatcaa
    39421 ggtaccaatc gtgtcaaaaa tatctgtcaa tgagaaggca agaatggcca tcagagtttc
    39481 aggcaaacga gctgtatctg aaatcaaagc tcccaaacct tctgaaccaa gagctgcacc
    39541 aaagactgtc ttcaagtctt caaaggctgc accaacatgg ttattagcaa aatcgatact
    39601 agacaaatct accaaaccaa ctgcgatagc aagaacagtt gttgtcaaga tagagaggat
    39661 aattccccct ttaatccctt tgataacaaa gaagattgtg atagcaagtc ctgcaagtgc
    39721 caccaaaaca gctgggttat taaagtcaac caatcctgga actgctgaag agtttgctgc
    39781 aatcgttgct ttagctttgt cagccccttc tcctacaaca gtatagttac ctggatcaat
    39841 cgtaaatttc aaaaatccag cattcttaat tcctacgtag gcaagaaaga caccgatacc
    39901 ggctgaaata gctgagcgaa gggcatttgg aatcgattca atgatcattt tacgaacatt
    39961 tgtcaaggta ataatcaatg agataagccc acagatgaag accatagcta gggcttgttg
    40021 ccaagaataa ccgagtccaa atacaactgt aaaggtaaag aaggcattga gtcccatacc
    40081 tggcgcttga gcatatggca agttggcgta gaaggccatc atcagggtac cagcaactgc
    40141 accgataatc gtcgctagga agacgccctg agcaggcatt cctgtttgtg aaagtatttg
    40201 tgggtttaca aagagaatat agctcattgc aaagaaagtt gttaaaccag cgagaacctc
    40261 tgtacgaacg tctgtaccgt tctcttttag tttaaataat ttgtccatca tcaatctcct
    40321 tttaattttt acgaacaata atagaattat atcatttatc attcactttt tcaatgtctt
    40381 tgtttgattt gtttaagaaa ttaatccaat ttcatttttt gtttggaatc tgcttttctg
    40441 cctgctttct gttataatag aagacatctt atctgaaaac acactagaaa ggtccatatg
    40501 acgaaaaaaa ttattgcagt tgacctggat ggaaccctgc tcaactcaga cagtcaaatt
    40561 tctgacttta ccaaaaaaac catcaaaaaa gttgctgaaa aaggccatca ggttattatt
    40621 acgacaggtc gcccttaccg tatgtcaaaa gatttttacc gtgaactggg cttagacact
    40681 cctatgatta acttcaacgg atcccttact catttaccag accaagtttg ggattttgaa
    40741 aagtgtttga ctgtagacaa aaaatatctg ctagatatgg ttcaacgttc agaggacatt
    40801 caagccgatt ttatcgctgg agaatatcgt aaaaaattct acattacaaa tcccaatgaa
    40861 gagattgcca atcccaaact atttggtgta gaagctttcc agcctgaaga tcaattccag
    40921 cctgaattgg tgaccaagga ccctaactgt atcctcttgc agaccagagc cagtgacaaa
    40981 tatgccttgg caaaagacat gaacgccttc taccagcatc aactttctat caatacctgg
    41041 ggaggtccgc tcaatatcct tgaatgtacc ccaaaaggtg tcaacaaggc ctttgctttg
    41101 gactacttgc tcaagataat gaatcgtgac aaaaaagatt tgattgcctt tggagatgaa
    41161 cacaatgata ccgaaatgct cgcttttgct gggaaaggtt atgccatgaa aaatgccaat
    41221 ccagagctac tcccttatgc agatgagcaa atttccctta ccaacgacca agatggggtt
    41281 gccaaaaccc tacaagactt attcttatag cctacactga tactcaatga gaatcaaaga
    41341 gcaaactagg aagctagccg taggttgctc aaagcactgc tttgaggttg tagatgaagc
    41401 tgacgtggtt tgaagagatt ttcgaagagt atgaccagct tgcaagctgg tctttgtgct
    41461 cttttcacag tctcatcaac cagttaatcg attgttctac tttttgtctc caaaaccttg
    41521 gaaaaggctt tcttttgtga tatacttcac atataaatac aagagagctc gtcacactcg
    41581 actctgttga caaaaaatca atccagtccc gttgtccctg ttctcggtca atatcaagga
    41641 ggatagctat gaaagctgtt gttgtaaatc cagaaagcac tggtgttgct attgaagaaa
    41701 aagtactccg tccacttgaa actggggaag cacttgtaga agttgaatac tgtggcgttt
    41761 gccacaccga cctccacgtt gctcatggtg actttggtca agtcccagga cgtgttcttg
    41821 ggcacgaagg tatcggtatc gttaaagaga ttgctccaga tgtgaaaagc cttaaagtcg
    41881 gtgaccgcgt cagcgttgct tggttctttg aaggatgtgg cacttgcgaa tactgtacaa
    41941 ctggtcgcga aaccctttgc cgtacagtga aaaatgctgg ctactcagta gacggtggta
    42001 tggctgaaca atgtatcgta actgctgact atgctgtcaa agttcctgac ggacttgatc
    42061 cagcccaagc ttcttctatc acatgtgctg gagtaacaac ctataaagct atcaaagaag
    42121 caaaagttga accaggccaa tgggttgttc tttacggtgc tggtggactt ggtaacctcg
    42181 ctgttcaata cgctaaaaaa gtattcaatg ctcatgttat cgcagtcgat atcaacaatg
    42241 acaaacttac ccttgcaaaa gaagtaggcg ctgacattgt gattaacggc ctcgaagttg
    42301 aagatgtagc tggactcatt aaagaaaaaa ctgatggagg agctcattca gctgtcgtaa
    42361 ctgctgtgtc taaagttgcc ttcaaccagg ctgttgactc cattcgtgct ggtggtcgcg
    42421 tcgtcgctgt tggtcttcct tctgaaatga tggaactcag catcgttaaa acagtcctcg
    42481 atggaatcca agtcatcggt tctcttgtcg gaactcgtaa agacttagaa gaagccttcc
    42541 aatttggtgc agaaggtctg gtagtcccag ttgttcaaaa acgtccagta gaagatgctg
    42601 ttgccatttt cgacgaaatg gaaaaaggcc aaatccaagg acgtatggta ctcgacttca
    42661 cccactaatt taatagaaac ctattttaaa agttggaagc ttcttccaac ttttttatat
    42721 taaattttaa ataagaattc aagattactc ctcaaaaact caacatatca acatacaaaa
    42781 ataaaaattt tttaattttt tatgataaat agttgctttt tttatgaaaa cggtttatac
    42841 ttaaacagtc ttaaagtttt cttaaatgaa aactaaaaca aaaaaggagg aatgacaata
    42901 atgagtatcg gaatcattat tgcgagccac ggcgaatttg ctgcgggtat tcatcagtca
    42961 ggatctatga tctttggtga acaagaaaag gttcaagttg tgacctttat gccaaatgaa
    43021 ggtcctgatg atctatacgc taagtttaat aacgctgttg ctgcatttga cgcagaagat
    43081 gaggttctag ttttggctga cctttggagt ggttctccat ttaaccaagc tagtcgcgtg
    43141 atgggagaaa atcctgagcg taagtttgcc atcatcacag gacttaactt accgatgttg
    43201 attcaagcct acacagagcg cctcatggac gctgctgcag gtgtagaaaa agtcgctgct
    43261 aatatcatta aagaagccaa agatggcatc aaagctcttc cagaagagct aaatccagtt
    43321 gaagaagttg caagcgctgc agctgctcca gttgcccaaa ctgctatccc agaaggaact
    43381 gttatcggag acggtaaatt gaaaatcaat cttgcccgtc ttgacacacg tctacttcac
    43441 ggtcaggttg caactgcttg gactccagat tcaaaagcaa atcgtatcat cgttgcttca
    43501 gataacgtgg ctaaagacga ccttcgtaaa gaattgatta aacaagcagc tccaggtaat
    43561 gtcaaggcta acgtggttcc aattcaaaaa ctgattgaga tttcaaaaga cccacgtttt
    43621 ggagaaacac atgcccttat cttgtttgaa acacctcaag atgcccttcg tgccatcgaa
    43681 ggcggcgtgc caatcaagac tcttaacgtt ggttctatgg ctcactcaac aggtaaaaca
    43741 ttggtcaata ccgttttgtc tatggacaaa gaagatgttg ctacatttga aaaaatgcgt
    43801 gacttgggtg ttgaatttga tgtccgtaaa gtaccaaatg attctaaaaa agatttgttt
    43861 gacttgatta acaaagccaa tgtcaaataa gccattattt atgaaaggat tttaaacatg
    43921 tctattattt ctatggtttt agtagtcgtt gtagccttct ttgcaggtct tgaaggcatc
    43981 ctcgaccagt tccaatttca ccaaccactt gtagcctgta cccttattgg gcttgtaaca
    44041 ggtcacttgg aagcagggat tatcctcggt ggatcgcttc aaatgattgc ccttggttgg
    44101 tcaaatatcg gtgctgctat cgctcctgat gctgcacttg cttctgtcgc tgctgccatt
    44161 atcatggttc ttggtggtga ctttaccaag actggtatcg gtgttgccca agcggttgct
    44221 atccctcttg ccgtagctgg acttttcttg acaatgattg ttcgtacaat ttcagttggt
    44281 ttggttcata ctgcagatgc tgccgctaaa aaaggtgact tcggcgctgt ggagcgtgcg
    44341 catttcattg cgctactctt ccaagggctt cgtatcgcgc ttcctgcagc tcttctcctt
    44401 atggtaccaa ctgaaactgt acaaagtatc cttagtgcca tgccagactg gctcaaagat
    44461 ggtatggcta tcggtggtgg tatggtcgtt gccgttggtt acgccatggt tatcaacatg
    44521 atggcaactc gtgaagtatg gccattcttc gctcttggtt tcgttctcgc tgctgtgtca
    44581 gatattactc taatcggatt cggtgctatc ggtgttgcta tcgctcttat ctaccttcac
    44641 ctttctaaaa ctggtggaaa tggtggcgga ggagccgcaa cttctaacga cccaatcggc
    44701 gatatcctag aagactacta agataagaaa ggactgaaaa catcatgact gaaaaacttc
    44761 aattaactaa atcagatcgt aaaaaagttt ggtggcgttc aaccttctta caagggtctt
    44821 ggaactttga acggatgcaa aacttgggct gggcttatac actcattcca gctatcaaaa
    44881 aactctatac taaaaaagaa gatcaaatcg ctgctcttga gcgtcacctt gagttcttca
    44941 acactcatcc atacgtagct gctccagtca tgggggttac tcttgcgctt gaagaagaac
    45001 gtgctaacgg tgtggaaatc gatgacgctg ctatccaagg ggttaaaatc ggtatgatgg
    45061 gacctcttgc tggtatcggt gacccagtat tctggtttac agtacgccca atccttggat
    45121 ctctcggtgc ttcacttgcc cttactggca atatcttggg gccactcctc ttctttgttg
    45181 catggaactt gattcgtatg tcattcttgt ggtatgttca agagattgga tacaaggctg
    45241 gatcagaaat cactaaagat atgtctggtg gtatccttca agatatcact aaaggagctt
    45301 ctatccttgg gatgttcatt cttgctgtcc ttgttcaacg ctgggtaaat attaaatttg
    45361 ctttcgatgt ttctaaagtt caactagatg aaaaggctta tatccattgg gataaattgc
    45421 cagaagggtc taaaggtatc caagaagcat tcgcacaagt aggacaagga ttgtctcaaa
    45481 ctcctgaaaa agttactact ttccaacaaa acttggatat gttgattcct ggattatcag
    45541 gactactcct tactttactt tgcatgtact tacttaagaa aaaagtatct ccaatcacta
    45601 ttatccttgc cctcttcgca gtgggtattg tggcacatgt tcttcacatc atgtaatcaa
    45661 gcaactaaaa aggaaccagg ttctaaaatc tgattccttt tttctatgct tttatttagc
    45721 caaggctccc attggatccc atggtgcaag tacaattggt tctgctccat aggcagcttg
    45781 ttcttctgct gtcagcaatt ccttacgaac aacgatttgg tatgtgtatt cgtccatcca
    45841 agcgtctgag gcaacaaagt aaccatctgt accgaccttg tctccccatg agttttcaac
    45901 cttccacttg gttgatttac cattttcgtc caagtcaaca cctgtcaaga ccatggcgtg
    45961 ggtcatcaag ctttcgctat agtccaaacg tccagccttg tcttgagtaa gtttaatgtc
    46021 catgcttgat tcaaagtcat aaacatctgt cgcaaggatt ccagccttac ggttactgag
    46081 ctggccgaca tcagaaccaa accaaacagt ctcacctgct tgcatttggg caatcgccaa
    46141 ttctttcaag cgctccattg gaacgttgat gtaacgaact gcacggctac caaccacatt
    46201 ccccaacatc tcaactgtgt aagattttcc gtaaggttta tcagcagttg gagcattgat
    46261 aacagaaacg tagtcttcta aaggaagatt gacatatttc ttgtagaact cttgtggtgt
    46321 gattcctttt tcacttttgt agttgttatc tttatcgcga taagcaaagt caaacttgcg
    46381 tggtggaagt cctaatgaca tagcaagaaa gttaaagatt tcttgcaaga ggtcttcttt
    46441 cttagcttga acagtcactt gatctgcacc agaaacaagc aaatcacgca agatttgagc
    46501 atcttgacga agcaatttat taaggatcgc atttagctca cgactgctgc tagatgaaac
    46561 agactcagga taaactgact taggcacgac accgtatttt tcaaagaggg aaacgaccat
    46621 atcccattga ccaccatctt gttgaggtgt ttggagtaag aagctaacct tgcggctagt
    46681 caattcttgg tctgaagtcg caatgacttg ctccaagaac cagtttgatt tctcatactt
    46741 atcccagaag aaagtgtggg cttgtgacaa ctcaaagttc tccaatttgt attgcgagat
    46801 gagtttgtgg cggaaggtgt tgagagccgc aaacatccag caacgaccag acgctttctg
    46861 gttagtgacc ttgtccttgg ttaaatccaa tgagaaaaca ggtgtgttgt ctacatggct
    46921 ttggcgacgt tccagagctg caaaaattcc gttgtggctg gcagcatttt caatcgcttg
    46981 gtattttaca tttgcttcat agttggcaaa tagtttatca gtaaatgatt cttgaatcgc
    47041 gttcatagat tcctcctttt attctacagt ctattataac tcttttcaca aaggaagcaa
    47101 ctaaaaaaca taaaaggtaa ggacattctc cctcaccttt ttcgaattta tactcttcga
    47161 aaatctcttc aaaccacgtc aacgtcgcct tgccgtactc aagtacagcc tgcggctagt
    47221 ttcctagttt gctctttgat tttcattgag tattaaacta aattaaataa tattagcgcg
    47281 gagaatttct aactcttcct tggtcaagcg acgccattct cctcgctgca agttctcatc
    47341 caatactaaa gttcccatag tcaaacgttg caagtctact acttccttgc cgcaatagcc
    47401 caccatacgc ttgacctgat gaaacttccc ttctgcaatg gtcacacgga tttggctttg
    47461 attctttttt gtatctacag acacaagctc cagtctagca ggctgacaag taaagtcttt
    47521 aagaggaatt cccttggcaa atgtctccgc atcttcttgg gtcataattc ccttgacctg
    47581 agccagatac gtcttatcca catgacgctt gggtgaaaga agagcatggg caagcttgcc
    47641 gtcattggtc aagagtaaaa gaccatgcgt gtcaatatcc aagcgtccta ctgggaaaac
    47701 ttccttgctc cgagcaatat catccagcaa gtccagaacg gttctgtgct tgggatcctc
    47761 agtcgctgag ataactcctt tgggcttgtt catcatgtag tagacaaact cttcatactc
    47821 caacacttgc ccatcaaagc gaatctcatc tctttcttca tcaatctgca atttagctga
    47881 cttttctttt ttaccattta ccgtcacgcg cccagacttg agcatgtttt tgacctctgt
    47941 ccgactccct acagcgcagg caactaaaaa tttatccaat ctcatagaac tattatatca
    48001 cactcaaaag gaggctgtct caatgaccaa cctccttttc gtttcatact cttc
//
LOCUS       DAVHTH010000011        46412 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.011, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000011 DAVHTH010000000
VERSION     DAVHTH010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 46412)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46412)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46412
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.011"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            <1..318
                     /locus_tag="VVR63_000627"
     CDS             <1..318
                     /locus_tag="VVR63_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000842495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6128669.1"
                     /translation="LIGPFVLLGTAVNTVATTLNGGATAGAFSGVALLLNALKIANLV
                     LGIIAIVYYKGDNRVGAAPSVLMIVFGGVSLIPFLGWVGGILVIIGGSLFLATLKKFK
                     SEE"
     gene            512..802
                     /locus_tag="VVR63_000628"
     CDS             512..802
                     /locus_tag="VVR63_000628"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6128670.1"
                     /translation="MIESIRTYADYIDLYKNIFDDYFTKAEEGFKGTAMENNDSFTKL
                     KESTQKLFDAQKKRLNNEDRIETTKNNVIAKHCQTVLSFLVLTSFFVKNCVK"
     gene            853..1545
                     /locus_tag="VVR63_000629"
     CDS             853..1545
                     /locus_tag="VVR63_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006703946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HEU6128671.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIKFDQAYTSVLKRAIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERAL
                     PFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDE
                     KLNVVSEYYLGK"
     gene            1598..4009
                     /locus_tag="VVR63_000630"
     CDS             1598..4009
                     /locus_tag="VVR63_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HEU6128672.1"
                     /translation="MIRNKKQDYVLAYKQPVSTTYMGWEEEALPIGNGSLGAKVFGLI
                     GAERIQFNEKSLWSGGPLPDSSDYQGGNLQDQYVFLAEIRQALEKRDYNLAKELAEQH
                     LIGPKTSQYGTYLSFGDIHIEFSQQGTTLSQVTDYQRQLNISKALVTTSYVYKGTRFE
                     REAFASFPDDLLVQRFTKEGAETLDFTIELSLTCDLASDGKYEQEKSDYKECKLDITD
                     SHILMKGRVKDNDLRFASYLAWETDGDIRVWSDRVQISGASYANLFLAAKTDFAQNPA
                     SNYRKKLDLEQQVIDLVDTAKEKGYTQLKSRHIEDYQALFQRVQLDLEANVDAFTTDD
                     LLKNYKPQEGQALEELFFQYGRYLLISSSRDCPDALPANLQGVWNAVDNPPWNSDYHL
                     NVNLQMNYWPAYVTNLLEAVFPVINYVDDLRVYGRLAAVKYAGIVSQKGEENGWLVHT
                     QATPFGWTAPGWDYYWGWSPAANAWMMQTVYEAYSFYRDQDYLREKIYPMLRETVRFW
                     NAFLHKDQQAQRWVSSPSYSPEHGPISIGNTYDQSLIWQLFHDFIQAAQELGLDEDLL
                     TEVKEKSDLLNPLQITQSGRIREWYEEEEQYFQNEKVEAQHRHASHLVGLYPGNLFSY
                     KGQEYIEAARASLNDRGDGGTGWSKANKINLWARLGDGNRAHKLLAEQLKTSTLPNLW
                     CSHPPFQIDGNFGATSGMAEMLLQSHAAYLVPLAALPDAWSTGSVSGLMARGHFEVSM
                     SWEDKKLLQLTILSRSGGDLRVSYPDIEKSVIKMNQEKIKAKCMGKDCISVATAEGDL
                     VQFYF"
     gene            4259..4960
                     /locus_tag="VVR63_000631"
     CDS             4259..4960
                     /locus_tag="VVR63_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6128673.1"
                     /translation="MAYIEMKHCYKRYQVGDTEIVANRDVNFEIEKGELVIILGASGA
                     GKSTVLNLLGGMDTNDEGEIWIDGVNIADYSSHQRTNYRRNDVGFVFQFYNLVSNLTA
                     KENVELASEIVTDALNPDQVLTDVGLAHRLNNFPAQLSGGEQQRVSIARAVAKNPKIL
                     LCDEPTGALDYQTGKQVLKILQDMSRQKGATVIIVTHNGALAPIADRVIHMHDASVKD
                     VVLNQHPQDIDSLEY"
     gene            4962..7670
                     /locus_tag="VVR63_000632"
     CDS             4962..7670
                     /locus_tag="VVR63_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEU6128674.1"
                     /translation="MIKRKTYWKDLIQSFTDSKGRFLSILILMMLGSLALVGLKVTSP
                     NMEATANAYLTTAQTLDLAVMSNYGLDQADQEELKQTEGAEVEFGYLTDVTMDNGQDA
                     IRLYSKPERISTFQLRKGRLPQSDREIALATHLQGQYSVGQEISFKEKEEGHSSLKDH
                     TYTITGFVDSAEILSQRDMGYAGSGSGTLTAYGVILPSQFDQKVYNIARLKYQDLAGL
                     NAFSSAYEEKSKQHQEDLEQTLSDNGKVRLQLLKKEGQESLDKGQETLDKAQTNLQEG
                     KRRLAAAQARIQAQESQLALFPQAQREQASAQLTQAKQELGKEEDKLKQAEQNLAQEK
                     EKLEKHQQVLDDLAEPRYQVYNRQTMPGGQGYLMYSNASSSIRAVGNIFPVVLYAVAA
                     MVTFTTMTRFVDEERTHAGIFKALGYRSKDIIAKFLLYGLVAGTVGTALGSILGHYLL
                     ASVISSVITKGMVVGETQIQFYWTYSLLALVLSWLASVLPAYLVAWRELHDEAAQLLL
                     PKPPVKGAKILLERIGFIWRRLSFTHKVTARNIFRYKQRMLMTIFGVAGSVALLFAGL
                     GIQSSVAGVPSKQFQQIQQYQMLVSENPSATNQDKVELAEVLKGQEILAYQKIYSKTL
                     DKDFKGRAGLQNITLMMIEKEDLTPFIHLQHHQQELTLKDGIVITAKLAQLAGVKVGQ
                     TLEIEGKELKVAAITENYVGHFIYMSQASYEQLYGQLPQANTYLVSLRDTSATSIESQ
                     AGLLMNQSAVSSVVQNASAIRLFDSIASSLNQTMTILVIVSVLLAIVILYNLTNINVA
                     ERIRELSTIKVLGFHNNEVTLYIYRETIVLSLVGIVLGLVAGFYLHQFLIQMISPATI
                     LFYPQVGWEVYVIPVAAVSIILTLLGFFVNYYLRKVDMLEALKSVE"
     gene            complement(7766..8257)
                     /gene="tpx"
                     /locus_tag="VVR63_000633"
     CDS             complement(7766..8257)
                     /gene="tpx"
                     /locus_tag="VVR63_000633"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HEU6128675.1"
                     /translation="MVTFLGNPVSFTGKQLQVGDKALDFSLTTTDLSKKSLADFDGKK
                     KVLSVVPSIDTGICSTQTRRFNEELAGLDNTVVLTVSMDLPFAQKRWCGAEGLDNAIM
                     LSDYFDHSFGRDYALLINEWHLLARAVFVLDTDNTIRYVEYVDNINSEPNFEAAIAAA
                     KAL"
     gene            complement(8380..9309)
                     /gene="psaA"
                     /locus_tag="VVR63_000634"
     CDS             complement(8380..9309)
                     /gene="psaA"
                     /locus_tag="VVR63_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein/adhesin PsaA"
                     /protein_id="HEU6128676.1"
                     /translation="MKKLGTLLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIAD
                     ITKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTK
                     LVENAKKTENKDYFAVSDGVDVIYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSA
                     KDPNNKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVP
                     SAYIWEINTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQ
                     IFTDSIAEQGKEGDSYYSMMKYNLDKIAEGLAK"
     gene            complement(9341..10189)
                     /locus_tag="VVR63_000635"
     CDS             complement(9341..10189)
                     /locus_tag="VVR63_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEU6128677.1"
                     /translation="MIAEFIDGLQKFHFLQNALITAIVVGIVAGAVGCFIILRGMSLM
                     GDAISHAVLPGVALSFILGLDFFIGAIVFGLLAAIIITYIKGNSIIKSDTAIGITFSS
                     FLALGIILIGVAKSSTDLFHILFGNILAVQDTDMFITMGVGAAILLLIWIFFKQLLIT
                     SFDELLAKAMGMPVNFYHYLLMVLLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKSMIFLSSTFGATASVLGLFIGYSFNVAAGSSIVLTAASFFLISFFIAPKQRYLKLK
                     NKHLLK"
     gene            complement(10186..10908)
                     /locus_tag="VVR63_000636"
     CDS             complement(10186..10908)
                     /locus_tag="VVR63_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEU6128678.1"
                     /translation="MIRIENLSVSYKETLALKDISLVLHGPTITGIIGPNGAGKSTLL
                     KGMLGIIPHQGQAFLDDKEVKKSLHRIAYVEQKINIDYNFPIKVKECVSLGLFPSIPL
                     FRSLKAKHWKKVQEALEIVGLADYAERQISQLSGGQFQRVLIARCLVQEADYILLDEP
                     FAGIDSVSEEIIMNTLRDLKKAGKTVLIVHHDLSKIPHYFDQVLLVNREVIAFGPTKE
                     TFTETNLKEAYGNQLFFNGGDL"
     gene            11199..13091
                     /gene="pepO"
                     /locus_tag="VVR63_000637"
     CDS             11199..13091
                     /gene="pepO"
                     /locus_tag="VVR63_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase PepO"
                     /protein_id="HEU6128679.1"
                     /translation="MTRYQDDFYDAINGEWQQTAEIPADKSQTGGFVDLDQEIEDLML
                     ATTDKWLAGEEVPEDAILENFVKYHRLVRDFDKREADGITPVLPLLKEFQELETFADF
                     TAKLAEFELAGKPNFLPFGVSPDFMDARINVLWASAPSTILPDTTYYAEEHPQREELL
                     TLWKESSANLLKAYDFSDEEIEDLLEKRLELDRRVVAVVLSNEESSEYAKLYHPYSYE
                     DFKKFAPALPLDDFFKAVIGQLPDKVIVDEERFWQAAEQFYSEEAWSLLKATLILSVV
                     NLSTSYLTEDIRVLSGAYSRALSGVPEAKDKVKAAYHLAQEPFKQALGLWYAREKFSP
                     EAKADVEKKVATMIDVYKERLLKNDWLTPETCKQAIVKLNVIKPYIGYPEELPARYKD
                     KVVNETASLFENALAFARVEIKHSWSKWNQPVDYKEWGMPAHMVNAYYNPQKNLIVFP
                     AAILQAPFYDLHQSSSANYGGIGAVIAHEISHAFDTNGASFDENGSLKDWWTESDYAA
                     FKEKTQKVIDQFDGQDSYGATINGKLTVSENVADLGGIAAALEAAKREADFSAEEFFY
                     NFGRIWRMKGRPEFMKLLASVDVHAPAKLRVNVQVPNFDDFFTTYDVKEGDGMWRSPE
                     ERVIIW"
     gene            complement(13214..13843)
                     /locus_tag="VVR63_000638"
     CDS             complement(13214..13843)
                     /locus_tag="VVR63_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEU6128680.1"
                     /translation="MKIHKTVNPVAYENTYYLEGEKHLIVVDPGSHWEAIRQTIEKIN
                     KPICAILLTHAHYDHIMSLDLVRETFGNPPVYIAESEASWLYTPVDNLSGLPRHDDMA
                     DVVTKPAEHTFVFHEEYQLEEFRFKVLPTPGHSIGGVSLVFPDAHLVLTGDALFRETI
                     GRTDLPTGSMEQLLHSIQTQLFTLPNYDVYPGHGPATTIAHEKAFNPFF"
     gene            14839..17061
                     /locus_tag="VVR63_000639"
     CDS             14839..17061
                     /locus_tag="VVR63_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HEU6128681.1"
                     /translation="MPKEVNLTGEEVVALTKEYLTEEDVHFVHKALVYAVECHSGQYR
                     KSGEPYIIHPIQVAGILAKLKLDAVTVACGFLHDVVEDTDATLDDLEREFGPDVRVIV
                     DGVTKLGKVEYKSIEEQLAENHRKMLMAMSEDIRVILVKLSDRLHNMRTLKHLRKDKQ
                     ERISKETMEIYAPLAHRLGISSVKWELEDLSFRYLNPTEFYKITHMMKEKRREREALV
                     DEVVTKLEEYTTERHLKGKIYGRPKHIYSIFRKMQDKRKRFEEIYDLIAIRCILDTQS
                     DVYAMLGYVHEFWKPMPGRFKDYIANRKANGYQSIHTTVYGPKGPIEFQIRTKEMHEV
                     AEYGVAAHWAYKKGIKGQVNSKESAIGMNWIKEMMELQDQADDAKEFVDSVKENYLAE
                     EIYVFTPDGAVRSLPKDSGPIDFAYEIHTKVGEKATGAKVNGRMVPLTTKLKTGDQVE
                     IIANPNSFGPSRDWLNMVKTSKARNKIRQFFKNQDKELSVNKGREMLMAQFQENGYVA
                     NKFMDKRHMDQVLQKTSYKTEDSLFAAIGFGEIGAITVFNRLTEKERREEERAKAKAE
                     AEELVKGGEVKVENKETLKVKHEGGVVIEGASGLLVRIAKCCNPVPGDDIVGYITKGR
                     GVAIHRVDCMNLRAQENYEQRLLDVEWEDQYSSSNKEYMAHIDIYGLNRTGLLNDVLQ
                     VLSNTTKNISTVNAQPTKDMKFANIHVSFGIANLSTLTTVVDKIKSVPEVYSVKRTNG
                     "
     gene            17091..17534
                     /locus_tag="VVR63_000640"
     CDS             17091..17534
                     /locus_tag="VVR63_000640"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HEU6128682.1"
                     /translation="MKIIIQRVKKAQVSIEGQIQGKINQGLLLLVGVGPEDQEEDLDY
                     AVRKLVNMRIFSDAEGKMNLSVKDIEGEILSISQFTLFADTKKGNRPAFTGAAKPDMA
                     SDFYDAFNQKLAQEVPVQTGIFGADMQVELVNNGPVTIILDTKKR"
     gene            complement(17801..17986)
                     /locus_tag="VVR63_000641"
     CDS             complement(17801..17986)
                     /locus_tag="VVR63_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6128683.1"
                     /translation="MKKIIFIKTIQLLVIDGIMLAFLTFKRGLTWDWILIYSGWLIFF
                     HPVLLTYLSNQLCDHFS"
     gene            complement(18005..18418)
                     /locus_tag="VVR63_000642"
     CDS             complement(18005..18418)
                     /locus_tag="VVR63_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6128684.1"
                     /translation="MKKLYRIHFIAIAVIDLLLFAFFIIRLETSFEWLLLSGLIFFLA
                     QGLLLFLLIVRLKHQFAEIYPQINKKIRFYYLGVLTIDFLFFVLLAFISSQRFSSLMS
                     IITACHSTFYYMTADYLRENYPDFYDKHISLWECL"
     gene            complement(18549..19196)
                     /locus_tag="VVR63_000643"
     CDS             complement(18549..19196)
                     /locus_tag="VVR63_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HEU6128685.1"
                     /translation="MVVGIAIASGYLNSRLDKFVDWGPWTALVPFGLISVTNVGISML
                     STRFTGKLSKWGNYFSIVNTILSGAIDYILGNKAAIITYPVTFLIYTFAIKKWKASQE
                     GRPNQISQKQVKLAVIIISIIAFLFAFVTNYIGYEGKMNLLAYVTTIAFALSLIANAL
                     NALKLTTQWGFWLIYNFVQLTKAGIQGNFANIGKYIFYILNAIGALFVWNDEEVR"
     gene            complement(19393..20043)
                     /locus_tag="VVR63_000644"
     CDS             complement(19393..20043)
                     /locus_tag="VVR63_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000188500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HEU6128686.1"
                     /translation="MTPNKEDYLKCIYEIGIDLHKITNKEIAARMQVSPPAVTEMIKR
                     MKSENLILKDKECGYLLTDLGLKLVSELYRKHRLIEVFLVHHLDYTSDQIHEEAEVLE
                     HTVSDLFVERLDKLLGFPKTCPHGGTIPAKGELLVEINNLPLADIKEAGAYRLTRVHD
                     SFDILHYLDKHSLHIGDQLQVKQFDGFSNTFTILSNDEDLQVNMDIAKQLYVEKIN"
     gene            20155..20997
                     /locus_tag="VVR63_000645"
     CDS             20155..20997
                     /locus_tag="VVR63_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HEU6128687.1"
                     /translation="MTKIALLSDIHGNTTALEAVLADAQQLGVDEYWLLGDILMPGTG
                     RRRILDLLDQLPITARVLGNWEDSLWHGVRKELDSTRPSQRYLLRQCQYVLEEISLEE
                     IEVLHNQPLQIHRQFGDLTVGISHHLPDKNWGRELIHTGKQEEFDRLVTHPPCDIAVY
                     GHIHQQLLRYGTGGQLIVNPGSIGQPFFLDAQLRKDLRAQYMILEFDDKGLVDMDFRR
                     VDYDVAAELQLAKDLRLPYFEVYYESLVNGIHHTHHQEFLRELAQKEGCDRELDDWLK
                     SGND"
     gene            21073..21510
                     /locus_tag="VVR63_000646"
     CDS             21073..21510
                     /locus_tag="VVR63_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HEU6128688.1"
                     /translation="MQIPSRFTIATHMLIIIALEGKESKVTSDFLAASVGVNPVIIRK
                     ILSQLKKAELISVARGTGGTEIVKDLKDISLLDVYQAVECLGKTGQLFSFHDNPNPNC
                     PVGAHIHDVLDQKLERIQLTMEAELGQTSLEKVVADAESQMKD"
     gene            21578..21880
                     /locus_tag="VVR63_000647"
     CDS             21578..21880
                     /locus_tag="VVR63_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000281600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6128689.1"
                     /translation="MYLVIGIVLAFIVSFWKDNRSLWNPVLFLLSLISSYFYLSYLFY
                     KNGYENVQLAFYVFAFVLLPFLLFLSGIFLIYNGVILLKREGRSKPHYLSMLFDFY"
     gene            complement(21971..23044)
                     /locus_tag="VVR63_000648"
     CDS             complement(21971..23044)
                     /locus_tag="VVR63_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HEU6128690.1"
                     /translation="MANIFDYLKDVAYDSYYDLPLNELDILTLIEITYLSFDNLVSTL
                     PQRLLDLAPQVPRDPTMLTSKNRLQLLDELAQHKRFKNCKLSHFINDIDPELQKQFAA
                     MTYRVSLDTYLIVFRGTDDSIIGWKEVFHLTYMKEIPAQKHALRYLKNFFAHHPKQKV
                     ILAGHSKGGNLAIYAASQIEQSLQNQITAVYTFDAPGLHQELTQTAGYQRIMDRSKIF
                     IPQGSIIGMMLEIPAHQIIVQSTALGGIAQHDTFSWQIEDKHFVQLDKTNSDSQQVDT
                     TFKEWVATVPDEELQLYFDLFFGTILEAGISSINDLASLKALEYIHHLFVQAQSLTPE
                     ERETLGRLTQLLIDTRYQAWKNR"
     gene            23200..23877
                     /locus_tag="VVR63_000649"
     CDS             23200..23877
                     /locus_tag="VVR63_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU6128691.1"
                     /translation="MHKILLIEDDQVIRQQVGKMLSEWGFEVVLVEDFMEVLSLFVQS
                     EPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSSRDQAMDIVMAINMGADDFVTKP
                     FDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
                     RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGI
                     GYGLKHA"
     gene            23870..24844
                     /locus_tag="VVR63_000650"
     CDS             23870..24844
                     /locus_tag="VVR63_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEU6128692.1"
                     /translation="MLDWKQFFLAYLRSRSRLFIYLLSLAFLVLLFQFLFASLGIYFL
                     YFFFLCCFVTILFFTWDILVETQVYRQELLYGEREAKSPLEIALAEKLEAREMELYQQ
                     RSKAERKLTDLLDYYTLWVHQIKTPIAASQLLVAEVVDRQLKQQLEQEIFKIDSYTNL
                     VLQYLRLESFHDDLVLKQVQIEDLVKEIIRKYALFFIQKGLNVNLHDLDKEIVTDKKW
                     LLVVIEQIISNSLKYTKEGGLEIYMDDQELCIKDTGIGIKNSDVLRVFERGFSGYNGR
                     LTQQSSGLGLYLSKKISEELGHQIRIESEVGKGTTVRIQFAQVNLVLE"
     gene            complement(24893..26836)
                     /gene="thrS"
                     /locus_tag="VVR63_000651"
     CDS             complement(24893..26836)
                     /gene="thrS"
                     /locus_tag="VVR63_000651"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HEU6128693.1"
                     /translation="MINITFPDGAVREFESGVTTFEIAQSISNSLAKKALAGKFNGKL
                     IDTTRAITEDGSIEIVTPDHEDALPILRHSAAHLFAQAARRLFPDIHLGVGPAIEDGF
                     YYDTDNTAGQISNEDLPRIEEEMQKIVKENFPSIREEVTKDEAREIFKNDPYKLELIE
                     EHSEDEGGLTIYRQGEYVDLCRGPHVPSTGRIQIFHLLHVAGAYWRGNSDNAMMQRIY
                     GTAWFEKKDLKNYLQMREEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATIRRE
                     LERYIVNKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVFKHHVHSYRELPIRIAEIGMMHRYEKSGALTGLQRVREMSLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSLRDPQDTHKYFDNDEMWENAQTMLRAA
                     LDEMGVDYFEAEGEAAFYGPKLDIQIKTALGKEETLSTIQLDFLLPERFDLKYIGADG
                     EDHRPVMIHRGVISTMERFTAILIENYKGAFPTWLAPHQVTLIPVSNEKHVDYAWEVA
                     KKLRDRGVRADVDERNEKMQFKIRASQTSKIPYQLIVGDKEMEDETVNVRRYGQKETQ
                     TVSVDNFVQAILADIANKSRVEK"
     gene            complement(26894..27217)
                     /locus_tag="VVR63_000652"
     CDS             complement(26894..27217)
                     /locus_tag="VVR63_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HEU6128694.1"
                     /translation="MELQELVERSWAIRQAYHELEVKHHDSKWTVEEDPLALSNDIGN
                     FQRLVMTKQGRYYDETPYTLEQKLSENIWWLLELSQRLDIDILTEMENFLSDKEKQLN
                     VRTWK"
     gene            complement(27648..27848)
                     /locus_tag="VVR63_000653"
     CDS             complement(27648..27848)
                     /locus_tag="VVR63_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001826938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6128695.1"
                     /translation="MRRFYSHLPYYLVILFFYWPLYELFLLVVSDPLTLKELYINNLL
                     FFTPLVILIVSLLYSYRFRFSL"
     gene            28086..28715
                     /locus_tag="VVR63_000654"
     CDS             28086..28715
                     /locus_tag="VVR63_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HEU6128696.1"
                     /translation="MKLAVIAANGQAGKAIVEEVVKRGHEVTAIVRSENKSQSESIIK
                     KDLFELTKDDLTGFDAVISAFGAYTPDTLPLHSKSIELFNQLLAGTQTRFLVVGGAGS
                     LYIDETKTTRLLDTSDFPEEFKSLAKAQADELDLLRTKNNLNWTFVSPAVDFIPDGEK
                     TGNYILAGEIFTTNEKGISQISYADYAIGLVDELEKGHHIKERISLLEK"
     gene            28856..29125
                     /gene="rpsO"
                     /locus_tag="VVR63_000655"
     CDS             28856..29125
                     /gene="rpsO"
                     /locus_tag="VVR63_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HEU6128697.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNEHIK
                     QHKKDHATYRGLMKKIGRRRNLLAYLRKNDVNRYRELINSLGLRR"
     gene            29940..30554
                     /locus_tag="VVR63_000656"
     CDS             29940..30554
                     /locus_tag="VVR63_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000531723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HEU6128698.1"
                     /translation="MGQTIISAIGVYISTSIDYLIILIILFAQLSQNKQKWHIYAGQY
                     LGTGLLVGASLVAAYVVNFVPEEWMVGLLGLIPIYLGIRFAIVGEDAEEEEEEIIERL
                     EQSKANQLFWTVTLLTIASGGDNLGIYIPYFASLDWSQTLVALLVFVIGIIIFCEISR
                     VLSSIPLIFETIEKYERIIVPLVFILLGLYIMYENGTIETFLIV"
     gene            complement(30846..31595)
                     /locus_tag="VVR63_000657"
     CDS             complement(30846..31595)
                     /locus_tag="VVR63_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HEU6128699.1"
                     /translation="MFYTYLRGLVVLLLWSINGNAHYHNTDKIPNQDENYILVAPHRT
                     WWDPVYMAFATKPKQFIFMAKKELFTNRIFGWWIRMCGAFPIDRENPSASAIKYPINV
                     LKKSDRSLIMFPSGSRHSNDVKGGAALIAKMAKVRIMPVTYTGPMTLKGLISRERVDM
                     NFGNPIDISDIKKMNDEGIETVANRIQTEFQRLDEETKQWHNDKKPNPLWWFIRIPAL
                     ILAIILAILTIIFSFIASFIWNPDKKREELA"
     gene            31728..34064
                     /locus_tag="VVR63_000658"
     CDS             31728..34064
                     /locus_tag="VVR63_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HEU6128700.1"
                     /translation="MDKNKIMGLTQREVKERQAEGLVNDFTASASTSTWQIVKRNVFT
                     LFNALNFAIALALAFVQAWSNLVFFAVICFNAFSGIVTELRAKHMVDKLNLMTKEKVK
                     TIRDGQEVALNPEELVLGDVIRLSAGEQIPSDALVLEGFAEVNEAMLTGESDLVQKEV
                     DGLLLSGSFLASGSVLSQVHHVGADNYAAKLMLEAKTVKPINSRIMKSLDKLAGFTGK
                     IIIPFGLALLLEALLLKGLPLKSSVVNSSTALLGMLPKGIALLTITSLLTAVIKLGLK
                     KVLVQEMYSVETLARVDMLCLDKTGTITQGKMQVEAVLPLMETYGEEAIASILTSYMA
                     HSEDKNPTAQAIRQRFVGDVAYPMISNLPFSSDRKWGAMELEGLGTVFLGAPEMLLDS
                     EVPEAREALERGSRVLVLALSQEKLDHHKPQKPSDIQALALLEILDSIREGAAETLDY
                     LRSQEVGLKIISGDNPVTVSSIAQKAGFADYHNYVDCSKITDEELMAMAEETAIFGRV
                     SPHQKKLIIQTLKKAGHTTAMTGDGVNDILALREADCSIVMAEGDPATRQIANLVLLN
                     SDFNDVPEILFEGRRVVNNIAHIAPIFLIKTIYSFLLAVICIASALLGRSEWILIFPF
                     IPIQITMIDQFVEGFPPFVLTFERNIKPVEQNFLRKSMLRALPSALMVVFSVLFVKIF
                     GSSQGWSELEISTLLYYLLGSIGFLSVFRACMPFTLWRVLLIVWSVGGFLATALFPRI
                     QKLLEISTLTGQTLPVYGVMMLVFTVIFILTSRYQARK"
     gene            34166..34843
                     /locus_tag="VVR63_000659"
     CDS             34166..34843
                     /locus_tag="VVR63_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HEU6128701.1"
                     /translation="MISKRLELVASFVSQGAILLDVGSDHAYLPIELVERGQIKSAIA
                     GEVVEGPYQSAVKNVEAHGLKEKIQVRLANGLAAFEETDQVSVITIAGMGGRLIARIL
                     EEGLGKLANVERLILQPNNREDDLRIWLQDHGFQIVAESILEEAGKFYEILVVEAGQM
                     KLSASDVRFGPFLSKEVSPVFVQKWQKEAEKLEFALGQIPEKNLEERQVLVDKIQAIK
                     EVLHVSK"
     gene            34830..35627
                     /locus_tag="VVR63_000660"
     CDS             34830..35627
                     /locus_tag="VVR63_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000881127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HEU6128702.1"
                     /translation="MLASEVIQAYEAFCPQEFSMEGDSRGLQIGTLDKGIQRVMVALD
                     IREETVAEAIEKGVDLIIVKHAPIFRPIKDLLASRPQNQIYIDLIKHDIAVYVSHTNI
                     DIVENGLNDWFCQMLGIEETTYLQETGPERGIGRIGNIQPQTFWELAQQVKQVFDLDS
                     LRMVHYQENDLQKPISRVAICGGSGQSFYKDALAKGADVYITGDIYYHTAQDMLSDGL
                     LALDPGHYIEVLFVEKIAALLTQWKEKKGWELEILPSQASTNPFRHI"
     gene            35644..36747
                     /locus_tag="VVR63_000661"
     CDS             35644..36747
                     /locus_tag="VVR63_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HEU6128703.1"
                     /translation="MKKVAIIGAGIVGATAAYYLSRESDLEVTVFDHEQGQATKAAAG
                     IISPWFSKRRNKAWYKMARLGADFYVDLLADLEKSGQEIDFYQRSGVFLLKKDESKLE
                     ELYQLALQRREESPLIGQLAILDQASANELFPGLQGFDNLLYASGGARVDGQLLVTRL
                     LEASHVKLVKEKVTLTLLSSGYQIGEEVFDQVILATGAWLGDMLEPLGYEVDVRPQKG
                     QLRDYQLAQDMEDYPVVMPEGEWDLIPFAGGKLSLGATHENDMGFDLTVDEPLLQQME
                     EAALPHYPVLARVTSRAERVGIRAYTSDFSPFFGQVPELAGVYAASGLGSSGLTTGPI
                     IGYHLAQLIQDKELTLDPLNYPIENYVKRVKSE"
     gene            37048..38067
                     /gene="galE"
                     /locus_tag="VVR63_000662"
     CDS             37048..38067
                     /gene="galE"
                     /locus_tag="VVR63_000662"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEU6128704.1"
                     /translation="MQEKILVTGGAGFIGTHTVIELIQAGHQVVVVDNLVNSNRKSLE
                     VVERITGVEIPFYEADIRDTATLRDIFKQEEPTGVIHFAGLKAVGESTRIPLAYYDNN
                     IAGTVSLLKAMEENNCKNIIFSSSATVYGDPHTVPILEDFPLSVTNPYGRTKLMLEEI
                     LTDIYKADSEWNVVLLRYFNPIGAHESGDLGENPNGIPNNLLPYVTQVAVGKLEQVQV
                     FGDDYDTEDGTGVRDYIHVVDLAKGHVAALKKIQKGSGLNVYNLGTGKGYSVLEIIQN
                     MEKAVGRPIPYRIVERRPGDIAACYSDPAKAKAELGWEAELDITQMCEDAWRWQSKHP
                     NGFED"
     gene            38069..39022
                     /locus_tag="VVR63_000663"
     CDS             38069..39022
                     /locus_tag="VVR63_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU6128705.1"
                     /translation="MMISIIVPCLNEEEVLPLFYQALEALLPDLETEIEYVFVDDGSS
                     DGTLELLKAYREQNPAVHYISFSRNFGKEAALYAGLQYATGDLVVVMDADLQDPPSML
                     FEMKNVLDKNVDLDCVGTRRTSREGEPFFRSFCAVLFYRLMQKISPVALPSGVRDFRM
                     MRRSVVDAILSLTESNRFSKGLFAWVGFKTYYLDYPNVERQAGKTSWSFRQLFFYSIE
                     GIVNFSDFPLTIAFVAGLLSCFLSLLMTFFVVVRTLILGNPTSGWTSLMAVILFLGGI
                     QLLTIGILGKYISKIYLETKKRPLYLIKEKSDLPDFTEKIK"
     gene            complement(39084..39290)
                     /locus_tag="VVR63_000664"
     CDS             complement(39084..39290)
                     /locus_tag="VVR63_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HEU6128706.1"
                     /translation="MKITLIPERCIACGLCQTYSDLFDYHDNGIVRFYDDPDQLEKEI
                     SPSQDVLEAVKNCPTRALIGNQEA"
     gene            39342..39818
                     /locus_tag="VVR63_000665"
     CDS             39342..39818
                     /locus_tag="VVR63_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM domain-containing protein"
                     /protein_id="HEU6128707.1"
                     /translation="MAKEPWQEDIYDQEESRAGRRHRNHGGADRMANRILTILASIFF
                     VIVVVMVIVLIYLSSGGSNRTAALKDFHDSDASVVQISSSSSSQPEQSSEPESTSSSS
                     EEAANPEGTIKVLAGEGEAAIAARAGISIAQLEALNPGHMATGSWFANPGDVIKIK"
     gene            39827..40498
                     /locus_tag="VVR63_000666"
     CDS             39827..40498
                     /locus_tag="VVR63_000666"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HEU6128708.1"
                     /translation="MKTIQIAIDGPASSGKSTVAKIIAKDFGFTYLDTGAMYRAATYM
                     ALKNQLGVEEVEALLALLDQHPISFGRSETGDQLVFVGDVDITHPIRENEVTNHVSAI
                     AAIPEVREKLVSLQQEIAQQGGIVMDGRDIGTVVLPQAELKIFLVASVDERAERRYKE
                     NIAKGIETDLETLKKEIAARDYKDSHRETSPLKQAEDAVYLDTTGLNIQEVVEKIKAE
                     AEKRM"
     gene            40629..40967
                     /locus_tag="VVR63_000667"
     CDS             40629..40967
                     /locus_tag="VVR63_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HEU6128709.1"
                     /translation="MNNLPNCPKCNSEYVYEDGALLVCPECAHEWNPAEVAEVEEGLV
                     AIDANGNKLTDGDTVTLIKDLKVKGAPKDLKQGTRVKNIRIVEGDHNIDCKIDGFGAM
                     KLKSEFVRKI"
     gene            40970..41599
                     /locus_tag="VVR63_000668"
     CDS             40970..41599
                     /locus_tag="VVR63_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Pr6Pr family membrane protein"
                     /protein_id="HEU6128710.1"
                     /translation="MSKHYKLVFYSRIFLFLAAFTGVYLEITRHGGFGMLLYYTVLSN
                     LLVTIFTLYLLKVMSRVGENWQRPSLLRLKGGVTMSIMITCVIYHFLLAPIATNFYTL
                     ENFLCHYIVPIWFLADTLFFDKQGQYKIWDPAVWTILPFLYMMFALFNGLVLKLNIPN
                     AKDNPFPYFFLNVNKGWNVVFKWCLIIFVAYMVAGFIFYFIKQIKRKSS"
     gene            41839..42990
                     /locus_tag="VVR63_000669"
     CDS             41839..42990
                     /locus_tag="VVR63_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEU6128711.1"
                     /translation="MKQFLERASILALSLVLITSFSISSALPAMFDYYQGYSKEQIEL
                     LVSLPSFGIMMMLLLNGFLEKIFPERLQISLGLLILSLSGTAPFWYQAYPFVFGTRLL
                     FGLGLGMINAKAISIISERYQGKRRIQMLGLRASAEVVGASLITLAVGQLLAFGWTAI
                     FLAYSAGFLVMPLYLLFVPYGKSKKEVKKRAKEASRLTREMKGLIFTLAIEAAVVVCT
                     NTAITIRIPSLMVERGLGDAQLSSFVLSIMQLIGIVAGVSFSFLISIFKEKLLLWSGI
                     TFGLGQIVIALSSSLWVVVAGSVLAGFAYSVVLTTVFQLVSERIPAKLLNQATSFAVL
                     GCSFGAFTTPFVLGAIGLLTHNGMLVFSILGGWLIVISIFVMYLLQKRA"
     gene            43303..44052
                     /gene="truA"
                     /locus_tag="VVR63_000670"
     CDS             43303..44052
                     /gene="truA"
                     /locus_tag="VVR63_000670"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HEU6128712.1"
                     /translation="MTRYKATISYDGYAFAGFQRQSHARSVQEEIEKTLTRLNKGQTI
                     TVHGAGRTDSGVHALGQVIHFDLPYQMDEEKLRFALDTQSPEDIDVISIELVADDFHC
                     RYAKHSKTYEFIVDRGRPKNPMRRHYATHFPYPLDVERMQIAIKKLEGTHDFTGFTAS
                     GTSVEDKVRTITEASLIVDETGQFLTFTFSGNGFLYKQIRNMVGTLLKIGNNRMPVEQ
                     IDLILEKKDRQLAGPTAAPNGLYLKEIRYEE"
     gene            44042..44815
                     /locus_tag="VVR63_000671"
     CDS             44042..44815
                     /locus_tag="VVR63_000671"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEU6128713.1"
                     /translation="MKNNRILALSGNDIFSGGGLSADLATYTLNGLHGFVAVTCLTAL
                     TEKGFEVFPTDDTIFQHELDSLRDVEFGGIKIGLLPTVSVAEKALDFIKQRPGVPVVL
                     DPVLVCKETHDVAVSELCQELIRFFPYVSVITPNLPEAELLSGQEIKTLEDMKTAAQK
                     LHDLGAPAVIIKGGNRLSQDKAVDVFYDGQTFTILENPVIQGQNAGAGCTFASSIASH
                     LIKGDKLLPAVESSKAFVYRAIAQADQYGVRQYEANKNN"
     gene            44793..45254
                     /locus_tag="VVR63_000672"
     CDS             44793..45254
                     /locus_tag="VVR63_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEU6128714.1"
                     /translation="MKQTKTTKIALVSLLTALSVVLGYFLKIPTPTGILTLLDAGVFF
                     AAFYFGSREGAVVGGLASFLIDLLSGYPQWMFFSLVNHGLQGFFAGFKGKSQWLGLIL
                     ATIAMVGGYALGSTLMNGWAAALPEILPNFMQNMVGMIVGFILSQSIKKIK"
     gene            45481..46412
                     /locus_tag="VVR63_000673"
                     /pseudo
     CDS             45481..46412
                     /locus_tag="VVR63_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611514.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT        13501 a         8681 c        10622 g        13608 t
ORIGIN      
        1 cttattggtc cttttgtctt gttgggaaca gcggtaaaca cagttgctac aactcttaat
       61 ggaggagcta ctgcaggggc tttttcaggt gttgccttac tcttgaatgc cttgaagatt
      121 gcaaatcttg ttcttggtat cattgctatt gtttactata aaggagataa tcgtgtaggt
      181 gcagctccgt ctgtactaat gattgttttt ggtggagtta gtctcattcc attcttagga
      241 tgggttgggg ggattcttgt tattatcgga ggatctctat tccttgcaac attgaagaaa
      301 ttcaaatcag aagaataaaa ggtattttag catgaaaaga acaaaaaagt ttatcggtat
      361 aggagtagct ctattatctc tttttcttct agttgcatgt ggaacataaa gttcaaagga
      421 tacttcaaca agtaatgatg agaagacagt agcaacatcc aatagttcaa aagaaacaat
      481 cactttcgat acaccggttg taacagacga tgtgattgaa tcaatacgca cttatgcaga
      541 ttatatagat ctttataaaa atatttttga tgattatttt actaaagctg aggaaggttt
      601 caaaggcaca gctatggaaa ataatgactc gtttactaaa ctaaaagagt caactcaaaa
      661 attattcgat gcgcagaaaa aaaggttaaa taatgaagat agaatagaaa caactaaaaa
      721 caatgtgatt gccaaacatt gtcaaacagt cctttccttt ttggttttga ctagcttttt
      781 tgtgaaaaat tgtgtaaaat agaatagata aacgagggga aacctcggaa aatttaaagg
      841 agaatccatc taatggtaaa attggttttt gctcgccacg gtgagtctga atggaacaaa
      901 gctaaccttt tcactggttg ggctgatgtt gatttgtctg aaaaaggtac acaacaagcg
      961 attgacgctg gtaaattgat caaagaagct ggtatcaaat ttgaccaagc ttacacttca
     1021 gtattgaaac gtgctatcaa aacaactaac ttggctcttg aagcttctga ccaattgtgg
     1081 gttccagttg aaaaatcatg gcgcttgaac gaacgtcact acggtggttt gactggtaaa
     1141 aataaagctg aagctgctga acaatttggt gatgagcaag ttcacatctg gcgtcgttca
     1201 tacgatgtat tgcctccaaa tatggaccgt gatgatgagc actcagctca cacagaccgt
     1261 cgttatgctt cacttgacga ctcagtaatc ccagatgctg aaaacttgaa agtgactttg
     1321 gaacgtgctc ttccattctg ggaagataaa atcgctccag ctcttaaaga tggtaaaaac
     1381 gtattcgtag gagctcacgg taactcaatc cgtgcccttg taaaacacat caaaggtttg
     1441 tcagatgacg agatcatgga cgtggaaatc cctaacttcc caccattggt attcgaattc
     1501 gacgaaaaat tgaacgtcgt ttctgaatac taccttggaa aataaaaaat tgtaagtcta
     1561 gaattgattt ctaggctttt tatgttagta tggaagtatg ataaggaata aaaaacaaga
     1621 ttatgtactg gcctacaagc aaccagtttc aaccacttac atgggttggg aagaagaagc
     1681 tttaccgata ggcaatggtt ctttaggagc aaaagtattt ggccttatag gggctgaacg
     1741 gattcaattt aatgaaaaaa gtctctggtc tggaggtcca cttcctgata gttcagatta
     1801 tcagggtgga aatcttcagg atcagtatgt ttttttagct gagattcggc aggctttgga
     1861 gaagagagat tacaatctgg ctaaggaact ggctgagcag cacctaattg ggccaaaaac
     1921 gagtcaatat gggacctatc tgtcttttgg ggatattcac attgagttca gccagcaagg
     1981 tacgactttg tctcaggtga cggactatca gagacagctg aatattagta aggcacttgt
     2041 gacgacttct tatgtctata agggaacgcg atttgaacgt gaagcttttg cgagttttcc
     2101 agatgatctc ttggttcagc gttttactaa ggaaggggcg gaaactctag attttactat
     2161 agaactatcc ttgacctgtg atttggcttc tgatggaaag tatgagcagg aaaaatctga
     2221 ttacaaggag tgtaagttgg atattactga ttctcatatc ttgatgaagg gaagagttaa
     2281 ggataatgat ctgcggtttg ctagttatct agcttgggaa acggatggag atattagagt
     2341 ttggtcagat agggttcaga tatcaggagc cagttatgcc aatctcttct tggccgctaa
     2401 gacggatttt gcccaaaatc ctgctagcaa ttatcgcaag aaactagatt tagagcaaca
     2461 ggtgatagac ttggtggaca cagctaaaga aaagggctat acccaattga aatcaaggca
     2521 tatcgaggac taccaagcct tattccagcg tgttcaattg gatttggaag ctaatgttga
     2581 cgcattcact acagatgatt tgttaaaaaa ttataagcca caagaagggc aggctttgga
     2641 ggagctgttc ttccagtatg gacggtattt attgattagt tcgtccagag actgcccaga
     2701 tgctctacca gctaacctac agggagtctg gaatgcggtc gacaatcctc cttggaattc
     2761 ggactatcac ttaaatgtca atctgcagat gaattattgg ccagcctatg ttaccaatct
     2821 cctagaggcg gtctttccgg tcatcaacta tgtagatgat ttgcgtgtct atggtcgtct
     2881 agcggctgta aagtatgcag gaatcgtctc tcaaaaaggt gaggaaaatg gttggttggt
     2941 tcatactcaa gcgactccct ttggttggac ggcacctggt tgggattact attggggttg
     3001 gtcaccagct gccaatgcgt ggatgatgca aactgtttat gaagcctatt cattttatag
     3061 ggaccaagac tatctcaggg agaaaattta tcccatgttg agggaaacgg ttcgtttttg
     3121 gaatgccttt ttacataagg atcagcaggc gcagcgttgg gtgtcttctc cgtcttattc
     3181 cccagaacat gggccgattt cgattggcaa tacttatgac caatctctga tttggcagtt
     3241 atttcatgat tttattcagg ctgctcagga attgggactg gatgaggact tgttgactga
     3301 ggttaaggag aagtctgatt tactaaatcc tttgcaaatc actcaatctg gtcgaatcag
     3361 ggagtggtat gaggaggaag agcagtattt tcaaaatgag aaagtggagg cccagcatcg
     3421 gcacgcttcc catctagtgg gactctatcc tggcaatctc tttagctaca agggacaaga
     3481 gtatattgaa gcggcacgtg ctagcctcaa tgatcgtgga gatggcggca caggctggtc
     3541 caaggctaat aagatcaatc tctgggcgcg tttgggagat ggcaatcgag cccataaatt
     3601 attggcagag cagttaaaaa catccacctt gccaaatctt tggtgtagcc atcctccttt
     3661 tcagatagat ggtaattttg gtgctactag tggcatggca gaaatgttac tccagtctca
     3721 tgcagcttat ctggtacctc tagctgccct acctgatgct tggtcaacag gttctgtttc
     3781 aggcttaatg gcacgtggac attttgaagt gagcatgagc tgggaagata aaaaactctt
     3841 acagttgacc attttatcaa ggagtggagg agatttgcga gtttcttatc cagatattga
     3901 gaagagtgtg attaaaatga atcaagaaaa aataaaagcg aaatgcatgg ggaaagattg
     3961 tatttcggtg gcaacagcag aaggtgatct tgttcaattt tatttttaag aagatgttat
     4021 aaggcagtaa tttgaaactt ccttttaata aggatttaag aatataggca gtttccaact
     4081 agttgaaaaa gcgttataat gataatagga agtaatactc aatgaaaatc aaagagcaca
     4141 aactaggaag ctagccgcag gttgctcaaa acagtgtttt gaggttgtag atggaagctg
     4201 acgtggtttg aagagagatt ttcgaggagt ataatttgtt tgatagaggg tgggtctgat
     4261 ggcttatatt gagatgaaac actgttacaa gcgttatcag gttggggaca cggagattgt
     4321 ggccaatcgt gatgtgaatt ttgagattga aaagggggag ctggttatta tccttggtgc
     4381 ttcaggtgca ggcaagtcaa cagttcttaa ccttcttggg ggaatggata ccaatgatga
     4441 aggggaaatc tggattgatg gtgttaatat tgcggattat agttcccacc agcgcaccaa
     4501 ttaccgtaga aatgatgtgg ggtttgtttt tcagttttat aatctagttt ctaatctgac
     4561 agctaaggaa aatgtggaac tggcttctga aattgtgaca gatgccttga atcctgatca
     4621 ggtcttgaca gatgtaggtc tggctcatcg tctcaataac tttccagccc agctttctgg
     4681 aggggagcaa cagcgagtct ccattgcacg cgcggtagcc aaaaatccta aaattctcct
     4741 ttgtgatgaa ccgactggag ccttggatta tcagacgggc aagcaggttt tgaaaattct
     4801 ccaagacatg tctcgtcaaa agggagcgac ggtgatcatc gtgactcata atggagcttt
     4861 ggcgcccatt gctgatcgcg tgattcatat gcacgatgcc agtgtcaagg atgtggtgct
     4921 caaccagcat cctcaggata ttgacagttt ggagtactag catgatcaag cgaaaaactt
     4981 attggaagga cttaattcag tccttcacag actccaaggg gcgtttttta tccatcttga
     5041 tcctgatgat gttgggatct ctagccttag taggcctcaa agtaaccagt cccaacatgg
     5101 aggcgacagc taatgcttat ttaacaactg ctcaaacctt ggatttggca gtcatgtcta
     5161 actatggctt ggatcaagca gaccaagaag aactaaaaca gacggagggc gcagaggtcg
     5221 agtttggcta tttgacagat gtgactatgg ataatgggca ggatgccatt cgactgtact
     5281 ccaaaccaga gcgaatttca acctttcagc taagaaaggg acgacttcct cagtcagaca
     5341 gggaaatcgc tttggccact catttgcaag gccaatacag cgtgggacag gagattagtt
     5401 ttaaagaaaa agaagagggt cattcctctt taaaagacca tacttatacc attactggtt
     5461 ttgtggattc ggctgaaatc ctctcccagc gagatatggg ctacgcagga agtggaagtg
     5521 ggactctgac agcctatggg gtgattttac ctagtcaatt tgatcagaaa gtctacaata
     5581 tagctcgttt gaaatatcaa gatttagcag gtttaaatgc cttttcatca gcttatgaag
     5641 aaaaatccaa gcaacatcag gaagaccttg aacaaacttt atcagataat ggcaaggtac
     5701 gtctgcaact tttgaaaaaa gaaggacaag agtctctaga caaggggcaa gagactcttg
     5761 acaaggctca gactaatttg caggaaggca agcgtcgttt agcagctgct caagctcgta
     5821 tacaggctca agaaagtcaa ctagccttgt ttcctcaagc tcagagagag caggctagtg
     5881 ctcaacttac ccaagccaag caggaactgg gcaaggaaga ggacaaacta aagcaagctg
     5941 aacaaaatct agcccaagaa aaggaaaaat tagaaaaaca tcagcaagtc ttggatgatt
     6001 tggcggagcc aaggtatcag gtttataatc gtcagaccat gccaggtggt cagggctatc
     6061 ttatgtatag caatgcttca tccagtattc gagcagtggg caatatcttt cctgtggtac
     6121 tttatgccgt agcagccatg gtgaccttta cgaccatgac tcgctttgta gacgaagagc
     6181 gaactcatgc agggattttt aaggccttgg gttatcgtag taaggatatt atcgccaagt
     6241 ttctccttta tggactagta gctgggactg tcggaacggc tctaggtagt atacttggtc
     6301 attatttgct agccagtgta atttcaagtg tcattacaaa aggcatggtg gtgggagaaa
     6361 cccagattca gttctattgg acctatagct tactagctct tgtcttgagc tggttggcga
     6421 gtgtgttacc agcctatctg gtggcttgga gggaacttca tgacgaagca gcccagcttc
     6481 tacttcctaa acctcctgtc aaaggagcta aaatcttatt ggagcgtatc ggttttatct
     6541 ggcgtcgtct cagttttact cataaggtaa cagcccgcaa catctttcgt tataagcaga
     6601 gaatgttgat gacaatcttt ggtgtggcag gttctgtagc tctgctcttt gcaggtttgg
     6661 gaatccaatc ttctgtagca ggagttccgt ctaaacagtt tcaacaaatc caacagtatc
     6721 agatgcttgt ctctgaaaat cctagtgcga ccaatcagga caaggtagag ctagcagaag
     6781 tgttgaaagg gcaggagata ctagcctacc agaaaatcta ttctaaaacg ctagacaagg
     6841 atttcaaggg cagggctggt cttcaaaaca ttactcttat gatgatagag aaggaagatt
     6901 tgactccctt tatccatctt caacatcatc agcaggagct gacattaaaa gatggcatcg
     6961 ttattacagc taaactcgcc cagctggcag gtgtcaaggt tgggcagact ttagaaattg
     7021 aaggtaagga actaaaggtc gctgctatta ctgagaacta cgttggtcac tttatttata
     7081 tgagtcaggc tagctatgag caactttacg gacagctacc ccaagccaac acttatctgg
     7141 tctcattaag ggataccagt gcaactagta tcgaaagtca ggcgggcttg cttatgaatc
     7201 aatctgcggt gtccagtgtt gtccaaaatg cttcagccat tcgactcttc gactctatcg
     7261 ctagctcact caatcagacc atgaccatct tggtcatcgt atcggttcta ttagctattg
     7321 tcatccttta caatctgacc aatatcaacg tagctgagag aatccgtgaa ctctccacta
     7381 tcaaggttct cggttttcat aataatgaag tcaccctcta catttaccgt gagacgattg
     7441 tgctgtccct tgtgggaatc gtacttggtc tggtagctgg tttctattta caccaatttt
     7501 tgattcaaat gatttcgcct gcgactattc tcttttatcc gcaggtaggc tgggaagtct
     7561 atgtaatccc agtggcagca gtaagcatca ttttgacctt gcttggtttc ttcgtcaatt
     7621 attatctgag aaaggttgac atgttagaag ccctgaaatc tgtagagtaa ggtagttatt
     7681 tttagctgat tgaacttcta tttactaata ttcaaaaatc ctccgtttca aagagcaggg
     7741 aactctttgt gacagaggat tttttctata gggctttagc agctgcaatt gcggcttcga
     7801 agtttggctc agaattgata ttatccacgt attcaacgta gcgaatcgta ttgtcagtat
     7861 cgaggacaaa gactgcgcgt gctaataggt gccattcgtt gatcaagagg gcataatcgc
     7921 gtccgaaaga atggtcaaag tagtctgaaa gcataatggc attgtcaagg ccttcagcac
     7981 cgcaccaacg tttttgagca aaaggtaggt ccattgaaac agtcaatacg accgtgttgt
     8041 ccagtccagc caattcttca ttaaaacgac gtgtttgagt tgagcagatg cctgtatcga
     8101 tagaaggaac gacactcaag acttttttct tgccatcaaa atcagccaga gattttttag
     8161 aaagatctgt tgtagtaaga gaaaaatcaa gcgccttgtc gccgacttgt agttgtttac
     8221 ctgtaaagct cacaggattt ccgagaaaag ttaccatagg atactccaat cttttttctt
     8281 ccattgtatc tgaaacagtc agaattttcc aatgatttga ccggaaatgt gtgcatagaa
     8341 aaaacgccag ctcacatgag aatgacgttt ttcagaggct tattttgcca atccttcagc
     8401 aatcttgtca aggttgtatt tcatcatgct gtagtagctg tcgccttctt taccttgttc
     8461 tgcgatagag tcagtaaaga tttgtgcgta gattgggatg tttgtgtctt gagaaacagt
     8521 tttcattgga cggtcatcca cacttgattc tacaaagagt gatggaactt ttgtttggcg
     8581 aagtttttca accaaggtct tgatttgttc aggagttcct tcttcttcag tattgatttc
     8641 ccagatgtag gcacttggga caccataggc tttagagaag tatttgaatg ctccttcgct
     8701 ggttacaatg agtttctttt cagcagggat cttattaaat ttatccttac tttctttatc
     8761 aagtttgtct aacttatcag tatattcttt gagatttttt tcatagaatt ctttattgtt
     8821 agggtctttg gcgctcaatt gtttggcgat atttttagca aaaataatac cgttttcaag
     8881 gttaagccaa gcgtgtgggt cttcttttcc tttttcattt tgaccttcaa ggtagataac
     8941 atcaacgccg tcgctgactg cgaagtagtc tttgttttca gttttcttgg cattttctac
     9001 caattttgta aaccaagcat tgccacctgt ttcaaggttg ataccgttat agaaaatcaa
     9061 atcagcctca gaagttttct taacgtcttc aggaagtggt tcgtattcgt gtgggtcttg
     9121 cccaatcgga acgatactat gaaggtcaat tttgtcacca gcaatatttt tagtaatatc
     9181 agcgatgatt gagtttgtag caacaacttt tagtttttga ccagaagttg tatctttttt
     9241 tccgctagca catgctacaa gaatgattgc agaaagaaag agaacgagta atgtacctaa
     9301 ttttttcatt agatcctcca atttattagg gctttgcccc ttattttaac aaatgtttat
     9361 ttttcagttt caaatatcgt tgtttgggag cgataaagaa gctaatgaga aagaaactag
     9421 cagctgtaag cacgatacta gaacctgccg caacattaaa actatagcca ataaagagtc
     9481 ccaaaactga agcagtagct ccgaaggttg aggaaaggaa aatcatgctt ttcagactat
     9541 tagcatacag ataagcagtt gcagctgggg taatcagcat ggctacaatc aggatagttc
     9601 cgacactttg catggctgtc acagacacga gagtcaggag taccatgaga aggtagtgat
     9661 agaaattgac aggcattccc atggctttag ccaagagttc atcaaaggaa gttatcaaga
     9721 gttgcttgaa gaaaatccag attaacaaga ggatggctgc ccccacaccc atagtaataa
     9781 acatatccgt atcttggacg gccagaatat taccaaaaag gatatggaaa aggtcagttg
     9841 aacttttagc gacaccaatc aagatgatac cgagggctaa gaaagaagaa aaggtaatgc
     9901 cgatggcggt atcgcttttg ataatcgagt ttcctttgat gtaggtaatg atgatggcag
     9961 ctagcaatcc aaagacaatg gctccgataa agaagtcaag gcccaagatg aaggagaggg
    10021 ctacacctgg taagacagca tgtgaaatgg catctcccat gagtgacatc ccgcgtagaa
    10081 taatgaaaca tcccacggct ccagctacaa tcccgacgac aatagctgtt atcaaggcat
    10141 tttgtaggaa atggaatttt tgcaatccat cgataaattc tgcaatcata ggtcacctcc
    10201 attgaaaaag agttgattac cgtaagcttc ttttagattg gtttcggtaa aagtttcttt
    10261 tgttggacca aaggcaatca cttctcgatt gacaagtaag acttgatcga agtagtgggg
    10321 aatcttgctg aggtcgtggt gaacgatgag aaccgtcttc ccagcttttt tcaaatctct
    10381 cagcgtattc atgatgattt cctcactgac agagtcaatc ccagcaaagg gttcatccaa
    10441 gaggatatag tcggcttcct gcaccaaaca tctggcaatc aagacccgct ggaattgacc
    10501 tccagacagt tgactaattt gacgttcagc gtagtcagct aggccgacga tttcaagggc
    10561 ctcttgcact ttcttccaat gtttagcctt taaacttcga aagagaggaa tagagggaaa
    10621 tagtcctaac gagacgcatt ccttgacctt gatgggaaag ttgtagtcga tattgatttt
    10681 ttgttcgaca taggcaattc ggtgtaagga ttttttaact tccttgtcat cgagaaatgc
    10741 ctgaccttga tgtgggataa ttcccagcat accttttaat agtgttgatt tcccagcgcc
    10801 gtttggacca atgatgccgg taattgttgg tccatggagc actagtgaaa tatccttaag
    10861 tgccaacgtt tctttgtagg agacactgag gttttcgata cgtatcataa acttgtattc
    10921 ctcctgtctc ttaatataca ttaaaaaaaa aattaagtca agttaatttt tgaaaaaatt
    10981 aaaataataa ctgaaaaata gattctaaag ataactttca ggataaattt ctaaattata
    11041 aaacgcatag tatcaagtgt aaaaaacttg gaattatgcg ttttatcatg gaaagatttt
    11101 ttataatagc taaaaaataa tagttaaatg gttattaatt gcattcccta gtgatttttg
    11161 ttaagataaa tgcaaataca aatgaaagcg agaacaagat gacacgttat caagatgatt
    11221 tttatgatgc tatcaatgga gaatggcaac agacagctga aatcccagca gataagtctc
    11281 aaacaggagg ttttgttgat ttagaccagg aaattgaaga cctgatgctg gcgacaacag
    11341 acaagtggtt agcaggtgaa gaagtgcctg aggatgctat cttggaaaac tttgtcaaat
    11401 accaccgcct agttcgtgat tttgacaaga gagaagctga cggtatcaca cctgtcttac
    11461 cactccttaa agaattccaa gaattggaaa cttttgcgga ttttacagct aaactagcag
    11521 agtttgagct tgcaggaaaa ccaaacttcc ttccttttgg tgtatcgcca gactttatgg
    11581 atgctagaat caatgttcta tgggctagcg ctccaagcac aatcttgcca gatacgacct
    11641 actatgcaga agaacatcct cagcgcgaag agctcttgac tctttggaaa gaaagcagcg
    11701 caaatctcct caaggcttat gatttctctg atgaagaaat tgaagacttg ctagaaaaaa
    11761 gacttgaatt ggaccgccga gttgtggcag tggtgctctc taatgaagaa agttcagaat
    11821 atgctaaact ctatcatcca tattcttacg aagatttcaa gaaattcgcg cctgccctac
    11881 ctttggatga cttcttcaaa gcagttattg ggcaattacc agacaaggtt attgtagacg
    11941 aggaacgttt ctggcaagca gcagagcaat tttacagtga ggaagcctgg tctctcctta
    12001 aagcaacctt gattttgagt gttgtcaatc tttcaaccag ctatttaaca gaggatatcc
    12061 gtgttttgtc tggtgcctac agccgtgccc tttctggagt tccagaggca aaagataagg
    12121 tcaaagcagc ttatcatcta gcacaggaac ctttcaagca agccctgggg ctttggtacg
    12181 cccgtgagaa gttctctcca gaagccaagg cggatgtgga gaaaaaagtg gcaaccatga
    12241 ttgatgtcta taaggagcgt ctgcttaaga atgactggct cactccagaa acctgtaaac
    12301 aggctatcgt gaagctcaat gtgatcaaac cttatattgg ctatccagaa gaattgcctg
    12361 cacgttacaa ggataaggta gtgaatgaaa ctgccagtct ttttgagaat gctctagcct
    12421 ttgcgcgtgt ggaaatcaag cacagttgga gtaagtggaa ccagcctgta gactataagg
    12481 aatggggcat gcctgctcat atggtcaatg cctactacaa tcctcagaag aacctgattg
    12541 tctttccagc ggccatttta caggcgcctt tctatgactt gcatcagtca tcttctgcta
    12601 actacggtgg tattggggca gtgattgccc atgaaatttc ccacgccttt gatactaacg
    12661 gggcttcctt tgacgaaaat ggtagcctca aggattggtg gacagagagc gactatgctg
    12721 ccttcaagga gaaaacacaa aaagtcattg accaatttga tggacaggat tcttatggag
    12781 caaccattaa cggtaaattg actgtatcag aaaacgtggc tgacttggga ggaatcgcag
    12841 cagcgcttga agcagctaag agagaagcag acttctcagc agaagagttc ttctacaact
    12901 tcggtcgcat ctggcgcatg aaaggtcgac cagaatttat gaaacttttg gctagcgtcg
    12961 atgtgcacgc accagccaaa ctccgtgtca atgtgcaagt accaaacttc gacgatttct
    13021 ttacaaccta tgatgtcaaa gaaggagacg gaatgtggcg ttcaccagag gagcgcgtga
    13081 ttatttggta atacaaaaaa tctagtcatc agaaaaaagg catccaatca cgtgtgaaaa
    13141 ccttgatagg atgccttttg taatagaaag atttgctgga tagtttactt aaatttcgat
    13201 tgtcatcatc ttgctagaaa aagggattga aggccttttc gtgagcgata gtagtagctg
    13261 gaccatgtcc tggatagaca tcgtagtttg gtagggtgaa gagttgggtc tggatactat
    13321 gaaggagttg ctccatgcta ccagtcggaa ggtcggtccg tccgatagtt tcgcggaata
    13381 gagcatctcc cgtcaagact aggtgagcat caggaaagac tagggaaaca ccaccgatag
    13441 agtgccctgg ggtcggtaga accttaaaac gaaattcctc tagttggtat tcttcgtgaa
    13501 agacaaaggt gtgttctgca ggttttgtga ccacatctgc catatcatcg tggcgaggga
    13561 gaccggagag attatcgaca ggagtgtaga gccagctggc ttcgctctct gcgatataga
    13621 caggaggatt gccaaacgtc tcgcgaacca agtccagact catgatatgg tcataatggg
    13681 cgtgggtcaa gagaatagca cagatcggtt tgttgatctt ctcgattgtc tgacgaatgg
    13741 cttcccaatg actaccagga tcgacgacga tgaggtgctt ttcgccttct agataatagg
    13801 tattttcata ggcaacagga ttcacggttt tatggatttt catactagct ccaatctcaa
    13861 agaatgtact aatactcttc gaaaatctct tcaaactgcg tcaactttat ctgcaacctc
    13921 aaagcagtgc tttgaacagc ctgcggctag ctttctagtt tgctctttga ttttcattga
    13981 gtataaatta agtatagcac agttagggag aataggtaag gatttaaaat gaacttaaaa
    14041 accagcatga ctagatgaag acaggctggt tatcaattta tcaatattgg aaaggtgtca
    14101 attgcccttc ataggttgca taaactccgt cattagcttg tttgatagac gtgatgttta
    14161 gagtgctacc gtagttggct tctcgtttgt cgctatattc actataagtt atcctactgg
    14221 gcaggttctg gtcgttagca tagtattgaa cgactgtttt ttatagcttt gctggctgaa
    14281 taggaacagg cagcaaactc ctaacattag gagagcaaag atagaaatag cagttttttt
    14341 cataggtatt ctccttataa actaaaggat agaagaaagt atcttgagga tttttatact
    14401 cttcgaaaat ctcttcaaac cgcgtcaacg tcgccttgcc gtatatatgt gactgacttt
    14461 gtcagtctta tctacaacct caaagcagtg ctttgagcaa cctgcggcta gtttcctagt
    14521 ttgctctttg attttcattg agtattaatt ccaaaatcca gtcaaggtac cagtgtatgt
    14581 gatacgagtt ccaccgttta tctttcgtat cttcaatgga attggggaaa tcagaaagtc
    14641 tttgggttac aatatggttt ccgttcttct atctctcctt ctatcaccta agtttaaaat
    14701 ctaacttcgt agtatattat gggccgataa ttcagaatta tcaagcaatt ttgaattatt
    14761 tttttcttat tctgttccaa tctagttttc atattcttaa aaaagtgata aaatggtagg
    14821 aagaattgga gagtagagat gccgaaagaa gtgaatttaa caggcgaaga agttgtcgct
    14881 ttaaccaaag aatatttaac ggaagaggat gttcattttg tccataaggc cttggtctat
    14941 gctgttgaat gccacagtgg tcaatatcgc aaatcaggcg agccttatat cattcaccct
    15001 atccaagtgg caggtatttt agctaagcta aagctggatg ctgtaacagt agcttgtgga
    15061 ttcttgcatg atgtggtgga agatacagat gcgaccttgg acgatttgga aagagagttt
    15121 ggtcctgatg tgcgggtgat tgttgacgga gttaccaagc ttggcaaggt cgagtacaaa
    15181 tcaatcgagg agcaattagc ggaaaatcat cgcaagatgc tcatggccat gtctgaggac
    15241 atccgcgtta ttttggtcaa actgtctgac cgcttgcaca atatgcggac cctgaaacat
    15301 cttcgaaaag acaagcagga gcgtatttcc aaagaaacca tggaaatcta tgccccactt
    15361 gcccatcgtt tggggatttc cagtgtcaaa tgggaattag aagacttgtc tttccgttat
    15421 ctcaatccaa cggagtttta caagattacc catatgatga aggaaaagcg cagggagcgt
    15481 gaggccttgg tggatgaggt agtcacaaaa ttagaggagt atacgacaga acgtcacttg
    15541 aaagggaaga tttatggtcg tcccaagcat atttactcaa ttttccgcaa aatgcaggac
    15601 aagagaaaac ggtttgagga aatctatgat ctgattgcta ttcgttgtat tttagatacc
    15661 caaagtgatg tttatgccat gcttggttac gtgcatgaat tttggaaacc gatgccaggt
    15721 cgcttcaaag actatattgc caaccgcaag gccaatggtt atcagtctat ccatacgact
    15781 gtttatgggc caaaagggcc gattgaattc cagattcgaa ccaaggaaat gcacgaggtg
    15841 gctgagtacg gggttgcggc tcactgggct tataagaaag gtataaaggg gcaagttaac
    15901 agcaaggaat cagctattgg aatgaactgg atcaaggaga tgatggagct ccaagaccag
    15961 gctgatgatg ctaaggaatt tgtggactct gttaaggaaa actatctggc tgaggagatt
    16021 tacgttttta ccccagatgg agctgtccgt tcccttccca aagattcagg accgattgat
    16081 tttgcctacg aaatccatac caaggtcggt gaaaaagcaa ctggtgccaa ggtcaatggc
    16141 cgcatggttc cactgacaac caagttaaag acaggggatc aggttgaaat tatcgccaac
    16201 ccgaactcct ttggacctag ccgtgactgg ctcaatatgg tcaagactag caaggcgcgc
    16261 aataagattc gccagttctt taaaaaccaa gataaggaat tgtctgtcaa caagggtcgt
    16321 gagatgctga tggctcagtt ccaagaaaat ggctatgtgg caaataaatt tatggacaag
    16381 cgccacatgg atcaagttct gcaaaagacc agttacaaga cagaagactc cctctttgcg
    16441 gccattggtt ttggggaaat cggtgcgatt accgtcttta accgtctgac tgaaaaggaa
    16501 cgccgtgagg aagagcgtgc caaggccaag gctgaggcag aggagcttgt caaaggtggc
    16561 gaggtcaagg ttgaaaataa agaaactctc aaggtcaagc atgagggggg agtggttatt
    16621 gaaggtgctt ctggtctcct agtgcggatt gctaagtgtt gtaaccccgt gcctggtgac
    16681 gatattgttg gctacattac caagggtcgt ggtgtggcta ttcaccgtgt ggactgtatg
    16741 aatctgcgtg cccaagaaaa ctacgagcaa cgtctccttg atgtggaatg ggaagaccag
    16801 tactctagct caaataagga gtatatggcc catatcgata tctacggtct caaccgtaca
    16861 ggactgttga acgatgtact gcaagttctt tcaaatacaa ccaagaatat ttcaacggtc
    16921 aatgcccaac caaccaagga tatgaagttt gctaatatcc atgtgtcctt cggtattgcc
    16981 aacctctcta cactgaccac ggttgtcgat aaaattaaga gtgtgccaga agtttactct
    17041 gtcaaacgga ccaacggcta gttgtcctag ctcttactag aaaggctatt atgaaaatca
    17101 ttatccaacg ggttaaaaaa gcccaagtga gtatagaagg ccagattcag ggaaaaatca
    17161 atcagggact tttattgctg gttggtgttg gaccagagga ccaagaggaa gatttggact
    17221 atgctgtgag aaaactggtc aatatgcgga ttttttcaga cgcagaaggc aagatgaacc
    17281 tgtctgtcaa agatattgaa ggagaaatcc tctctatttc tcagtttacc ctctttgcgg
    17341 atactaagaa aggcaatcgt ccagccttta caggggcagc taaacctgat atggcatcag
    17401 acttctatga tgctttcaat caaaaattag cgcaagaagt gcccgttcag acaggtatct
    17461 ttggagcaga tatgcaggtt gagctggtta ataacggacc tgttaccatt atcctagata
    17521 ctaaaaagag ataagaaaga ccaagcccag tcggcttggt ctttctcatc tatcataaaa
    17581 tactccaaaa agaaatcggt tcttgatatg cttgggggaa gtctcttttc aggctttggc
    17641 agatgcgata ggaagggatg aggtgtccta ggatgaggag agttccctga aggaaaagtg
    17701 gaatatcact taaagacacc aaggagagaa tcatcaggct atcccatagg agaatttgta
    17761 aagcaaaacg ccagaatctc ggtctaatct gggaatagag ttaactaaag tggtcacaaa
    17821 gttggtttga aagataggtc aatagcacag gatgaaagaa aatgagccaa ccgctataaa
    17881 tcaaaatcca gtcccaagta agcccccttt taaatgtcaa aaatgccagc atgattccat
    17941 caatgacaag gagttgaatg gttttgatga agatgatttt tttcatgcta aaacctcctt
    18001 ttccttagag acactcccat aaagagatgt gtttgtcgta aaagtctgga tagttttctc
    18061 ttaggtagtc agctgtcata taataaaaag tagaatggca agcagtgata attgacataa
    18121 gagatgaaaa acgctgagaa ctaatgaagg ctaagagaac aaaaaataga aaatcaatgg
    18181 tgagaacccc taaatagtag aagcgaatct ttttattgat ttgaggataa atctcagcga
    18241 attgatgttt gagtcggacg atcaagagaa atagcaggag tccttgagca aggaagaaaa
    18301 ttaaaccaga gagcaagagc cactcaaaag atgtctcgag tctaatgata aaaaatgcaa
    18361 atagtagcaa atcaataact gcaattgcta taaaatggat tctatagagt tttttcatga
    18421 caagacctcc ctcttttatc taacttcatt ctactccaaa agaatgggag ttacaactaa
    18481 aatgataaaa atagcagaag ggagattctc ttaagttggc tagtattctt tatttgagtt
    18541 tccttctatt atctaacttc ttcatcattc cagacaaata aagctccgat tgcattgagg
    18601 atataaaaga tgtatttacc gatattggcg aagtttcctt gaataccagc ttttgtcagc
    18661 tgaacgaaat tgtaaatcaa ccaaaagccc cactgagttg ttagttttaa tgcattcaaa
    18721 gcattggcaa tgagggatag tgcaaaggca atagttgtta cgtaggcaag gagattcatc
    18781 ttgccctcat atccgatata gttggtcaca aaggcaaaga ggaaggcgat gatggaaatg
    18841 atgatgaccg ccaattttac ctgtttttgg cttatttggt tgggtctgcc ttcttgcgaa
    18901 gctttccatt tctttatagc aaaggtataa atgaggaagg tgacgggata ggtaatgatg
    18961 gccgccttat ttccaaggat ataatcaata gcaccggaca aaatggtatt aacaatacta
    19021 aagtaatttc cccatttgct taatttcccc gtgaaacgag tggacaacat ggaaatccca
    19081 acgttggtta cggaaatcaa tccaaagggt acaagagctg tccatggtcc ccagtctaca
    19141 aatttatcga ggcgtgagtt gaggtaacca gatgcaatcg caatcccaac gaccaaagca
    19201 accccgaaga ggtcaaacca ttgaagaggt caaaccattt agatgtagca aaaattttta
    19261 gtgatttttt cataggttaa actacctttc tttttttttt caaatattct accaccaaat
    19321 gaaagtaaaa taaaatgata gaaataaaac cctgaaaata aaactttcag ggttggtagg
    19381 ggacttgaga aattagttga ttttctcgac atagagttgt tttgcaatgt ccatattcac
    19441 ttgtaaatcc tcgtcgttac tgaggatagt gaaggtattg ctgaagccat caaactgctt
    19501 gacttggagc tggtcaccga tgtgaagtga gtgcttgtcc agataatgga gaatgtcaaa
    19561 actatcgtgc acccgagtca ggcggtaggc gccagcttcc ttgatatcag ctagtgggag
    19621 gttattgatt tcaacgagta gttctccctt ggcaggaata gttcctccgt gggggcaggt
    19681 tttagggaaa cctagcagtt tatctagtct ttccacgaac aggtcagaga cagtgtgttc
    19741 caagacctca gcttcctcgt gaatctggtc acttgtatag tctaaatgat gaactagaaa
    19801 aacttcaatc aagcggtgct tacgatagag ctcagagacc agtttgagac cgaggtcagt
    19861 cagtagatag ccacattcct tgtcctttag gatgagattt tcacttttca ttcgtttgat
    19921 catttcagtt acggcagggg gagagacttg catgcgagcc gcaatttcct tgttggtaat
    19981 cttatgcagg tctatgccaa tttcataaat acattttaga tagtcttctt tgtttggggt
    20041 cattcgtttc ctcttgtcta atatctttat ctagtatatc aaaaaaagct agatttctct
    20101 agctgtgact ttttatgtta tacttattgc aagagaaaaa acgaggagat ggatatgacg
    20161 aaaatagctc ttctttcaga tattcatgga aataccaccg ccttggaggc tgttttggca
    20221 gatgctcagc agctaggagt ggatgaatac tggcttttgg gagatattct catgccaggg
    20281 acaggacgta gaaggatttt ggacttgttg gatcaactac cgattacggc tagagttttg
    20341 ggaaactggg aagacagtct ttggcatggt gtccgtaagg aattggacag tactcgcccc
    20401 agtcaacgct atctcttgcg ccagtgccag tatgttttag aggaaatttc cctagaagaa
    20461 attgaagtgc tccacaatca acctcttcaa attcatcgtc agtttgggga tttgacggtg
    20521 ggaattagcc atcatctgcc tgataagaac tgggggcgag agttgattca tactggcaaa
    20581 caagaggagt ttgaccgctt ggtgactcat cctccctgtg atattgctgt ttatggacat
    20641 attcaccagc agttgcttcg ttacgggact ggtgggcaat tgattgtcaa tccgggttcg
    20701 attggccaac ctttcttttt ggacgctcag ctacggaagg acttgcgggc ccagtatatg
    20761 attttggagt ttgatgacaa aggcctggta gatatggact tccgacgggt agactacgat
    20821 gtggcagcgg aattgcagct ggctaaagac ctgagacttc cctattttga ggtttactat
    20881 gaaagtctgg tcaatgggat ccaccatact catcatcagg aatttttgag agaattggct
    20941 cagaaagagg gctgcgatcg ggagttagac gactggttga aaagtggtaa cgattgacat
    21001 tacaactaaa aagggtataa taatagaaaa agaagagtag aggcagggta gcctcgtaaa
    21061 aaggagaaga ggatgcaaat tccaagtaga tttaccattg cgactcatat gctgataatc
    21121 attgccctcg aggggaagga aagcaaggtg accagtgatt ttctggctgc tagtgtcggg
    21181 gtcaatcctg tcattatcag aaagatcttg tcccagttga agaaggcaga gctgatttca
    21241 gtagcgcgtg gaacgggcgg aacagagatt gtcaaggacc ttaaggatat tagtctttta
    21301 gatgtttatc aggcggtcga atgtcttggt aagacaggtc aactcttcag tttccatgac
    21361 aatccgaatc caaattgccc tgtaggagct catattcatg atgttttgga tcaaaaattg
    21421 gagagaattc agttgactat ggaggcagaa cttggtcaaa ccagtctaga aaaagtcgtg
    21481 gccgatgcag agagtcagat gaaggattaa gagggataaa tgccctcttt tttctttgga
    21541 taattatgat aaaatgtagc tattaaagga gtaagaaatg tatctcgtta taggaattgt
    21601 attagccttt atagtgtcat tttggaagga taatagaagt ttgtggaatc cagtattatt
    21661 tttattatcc ctcatttcaa gttattttta tctatcctac cttttttata aaaatggata
    21721 cgagaatgtt cagttagctt tttatgtatt tgcctttgtc ttacttcctt ttttgctttt
    21781 tctaagtggc atctttttaa tctataatgg ggtcattttg ttgaagcgag agggacgttc
    21841 caagccccat tatctctcaa tgctctttga tttttattga ctattagatt ctatttaaaa
    21901 agacttagaa tgcacatgaa agtatgtatt ctaggtcttt tgttttgtat acatttaatt
    21961 ttcaagagta ttatctattt ttccatgcct ggtaacgagt atcaatcaat aactgggtaa
    22021 ggcgacccaa ggtttctctt tcttctggag tgagggattg agcttggaca aagagatgat
    22081 gaatgtattc aagcgctttt aaggaagcca agtcattgat agagctaata ccagcctcaa
    22141 gaatagtgcc aaagaagagg tcgaagtaga gctgaagttc ttcgtcaggg actgtggcca
    22201 cccattcttt aaaggttgtg tctacttgct ggctatcact gttggtctta tccagttgga
    22261 cgaagtgctt gtcctcaatc tgccaactaa aggtatcgtg ctgggcgatg ccacccaggg
    22321 cagtactctg aacgatgatt tggtgagcag gaatttccag catcataccg ataatggaac
    22381 cttgtggaat gaatatcttg cttctatcca ttatcctttg ataacccgca gtctgtgtca
    22441 attcttgatg gagaccaggt gcatcaaatg tataaactgc tgtgatctga ttttgcaaac
    22501 tttgctcaat ttggctagca gcatagatag cgagatttcc tcccttggaa tgcccagcta
    22561 gaataacctt ttgcttagga tgatgggcaa aaaagttctt taaatagcga agggcgtgct
    22621 tttgagcagg aatttccttc atataggtca ggtggaaaac ttccttccag ccaatgatac
    22681 tgtcatctgt cccacgaaag acaatcagat aggtatcgag gctgacacga taagtcatag
    22741 ccgcaaattg cttttgcagt tcagggtcga tgtcgttgat aaaatgggag agtttgcaat
    22801 ttttgaagcg cttgtgttga gccaattcat ctaataattg aaggcgattt ttgctagtaa
    22861 gcatggtggg atctcttgga acctgaggtg ctagatctaa aagacgttga ggaagtgtgg
    22921 agaccagatt atcaaaggag aggtaggtga tttctattaa ggttagaatg tctaactcat
    22981 tcaagggaag gtcgtaataa gaatcatatg cgacatcttt cagatagtca aaaatattgg
    23041 ccataagagc tcctttcttt ttatttatct tagcaaattt ccctcaaatt agctagtagc
    23101 attgcctgtt tgtactggct aaaaacaggc tatttcaaat tcagtttcag accatctggc
    23161 atggaaaaat ctgttataat aatagaaaag gagaagcgca tgcacaagat tttattaata
    23221 gaagatgatc aggtcattcg tcaacaggtc gggaaaatgc tctctgaatg gggatttgaa
    23281 gtggtcctgg tagaagactt tatggaagtt ttgagtctat ttgttcagtc ggaacctcat
    23341 ctggtcctca tggatattgg tttgcccttg tttaatggtt atcactggtg tcaggaaatc
    23401 cgcaagattt ccaaggtacc tatcatgttt ctttcttcga gagaccaggc tatggatatt
    23461 gtcatggcaa tcaatatggg ggcggatgac tttgtgacca agccttttga ccagcaggtt
    23521 cttttagcta aggttcaggg cttgttgcgt cgttcctatg agtttgggcg tgatgagagt
    23581 ttgctggaat atgctggtgt tatcctcaat accaaatcca tggatttaca ttatcaaggg
    23641 caagtcttga atttgaccaa gaatgaattc cagattttac gcgtgttatt tgagcatgca
    23701 ggcaacatcg tagcacgtga cgacctgatg cgggaacttt ggaacagtga ctttttcatt
    23761 gatgataata ccctctctgt caatgtggct cgtttgcgta aaaagttgga ggagcaggga
    23821 ttggtaggat ttatcgagac caagaaagga atagggtacg gattgaagca tgcttgattg
    23881 gaaacaattt tttctagcct atctgcgctc ccgtagtcgt ctttttatct atctgctttc
    23941 tttggcattt cttgtcttac tctttcagtt tttatttgcc agtctaggaa tttacttcct
    24001 ctactttttc ttcttgtgtt gctttgtaac catcttattt ttcacttggg acatattggt
    24061 ggaaacgcag gtctatcgcc aggaacttct ctatggagag agggaagcca agtctccttt
    24121 ggaaatagct ttagcagaaa aattagaagc gcgtgagatg gaactctatc agcagaggtc
    24181 aaaagcagaa agaaaactga cggatttgct ggattactat accttgtggg tccatcagat
    24241 aaagaccccc attgcagcca gtcaactctt agttgcagaa gtggtcgacc gccaactgaa
    24301 gcagcagcta gaacaggaaa ttttcaaaat cgactcctat accaacctag ttttacagta
    24361 cctgcgttta gaaagtttcc atgatgattt ggtcttaaag caggttcaaa ttgaggactt
    24421 ggtcaaggaa ataattcgta aatatgctct tttctttatt caaaaaggct taaatgtcaa
    24481 tctacatgac cttgataaag aaatcgtgac ggataaaaag tggctgctag tggttattga
    24541 gcaaatcatc tcaaacagtc tcaagtacac caaggaaggt ggtctggaga tttatatgga
    24601 tgaccaagag ctttgtatca aagatacggg aatcgggata aaaaacagtg atgtcctccg
    24661 agtatttgaa cgtggctttt caggatacaa tggccgtttg acccagcagt cctctggact
    24721 tggcctttat ctatctaaga aaatttctga agaactgggg caccagattc gtatcgagtc
    24781 tgaggtcgga aaaggaacga cagtgcggat tcagtttgct caagtgaact tagtccttga
    24841 gtaaaaatag atgagaaaaa gcctccagat tggaggcttt tatgctagac tcttatttct
    24901 caacgcgtga tttgttggcg atatcagcta ggatagcttg aacaaaatta tcaactgaga
    24961 cagtttgtgt ttctttttgg ccgtagcgac gaacgttgac tgtttcgtct tccatttctt
    25021 tgtctccaac aattaattgg taaggaatct tgctggtttg tgaagcacgg atcttgaact
    25081 gcattttttc attgcgctca tctacgtctg cacggacacc gcggtcacgg agtttcttgg
    25141 ctacttccca agcgtagtcc acgtgttttt cgttagatac tgggataagg gttacttggt
    25201 gtggtgccag ccatgttggg aaggcaccct tgtagttctc aatcaagata gctgtgaagc
    25261 gttccatagt tgagataacc ccacggtgga tcatgactgg acggtgatct tcgccatcag
    25321 ctccgatgta tttgaggtcg aagcgttctg gcaacaagaa atcaagttgg atagtagaaa
    25381 gggtttcttc ttttccaagg gcagttttaa tctggatatc caattttggt ccgtagaagg
    25441 ccgcttcacc ttcggcttca aagtagtcca cgcccatttc atcaagagct gcacgaagca
    25501 tggtttgggc attttcccac atctcatcgt tatcaaagta cttatgagta tcttgagggt
    25561 cacgaagaga gaggcggaag cggtagtcag tcaagttgaa gtcttcataa acatcgataa
    25621 tcaactgaag ggcacgttgg aattcttctt ggatttgttc tggagtaacg aataggtgac
    25681 cgtcgttgag tgacatttca cgtacacgtt gaaggccagt gagggcacca gatttttcgt
    25741 aacggtgcat cataccgatt tcagcgatac ggattggcaa ttcacggtaa gagtgaacat
    25801 ggtgtttgaa aacttggatg tggtgcggac agttcattgg acgaaggaca aattcttccc
    25861 cgtcacccat gtccatggtt gggaacatgt cttcttggta atgatcccag tggccagaag
    25921 tcttgtaaag ctcaacagaa gcaagtggtg gagtgtagac gtgttggtag ccagaagcca
    25981 actctttgtt tacgatgtag cgttccaatt cacgacggat agtcgcacca tttggcaacc
    26041 agaatggcaa accttgtccc acttcttgtg aaatcataaa gaggtcaagc tctttaccaa
    26101 gtttacggtg gtcacgttcc ttagcttctt cacgcatttg aaggtagttt ttcaagtctt
    26161 tcttttcaaa ccaagctgta ccgtagatac gttgcatcat agcgttgtcg ctgtttccac
    26221 gccagtacgc accagctaca tggagaaggt ggaagatttg gatacgacct gttgatggaa
    26281 cgtgaggtcc acggcagagg tctacatatt caccctgacg atagatagtc aaaccgcctt
    26341 cgtcttctga gtgttcttca atcaattcca acttgtaagg gtcatttttg aagatttcac
    26401 gtgcctcgtc tttagtcact tcttcacgaa tagatgggaa gttttctttg acgatttttt
    26461 gcatttcttc ttcgatacga ggaaggtctt cgttagagat ttgaccagct gtgttgtcag
    26521 tatcgtagta gaaaccatct tcgatggctg gaccaactcc caagtgaatg tctgggaaaa
    26581 gacgacgagc tgcttgggcg aacaagtgag ctgctgagtg gcgcaagatt ggaagggcat
    26641 cttcgtgatc aggtgtcaca atttcgatgc ttccatcttc agtgatagcg cgagtagtgt
    26701 cgatgagttt gccgttgaat ttaccagcca aggctttttt agctagggaa ttgctgatag
    26761 attgggcaat ttcaaaagtt gttacgccag attcgaattc acgaacagcg ccatctggga
    26821 aagtaatgtt aatcatgatg ttctcctttt ttattatttc atagtttcta agcattgatt
    26881 ttttatcatc agactacttc caagtcctaa cgttcaattg cttttcttta tcagagagga
    26941 agttttccat ttccgtcaga atgtctatat ccaaacgttg agaaagttct aatagccacc
    27001 agatattttc tgaaagtttt tgttccagtg tgtagggtgt ttcatcatag tagcgtcctt
    27061 gctttgtcat caccagtcgt tggaaatttc caatatcatt agataaagcc aaggggtctt
    27121 cttctaccgt ccacttggaa tcatgatgct taacttccag ttcgtgataa gcttgtcgga
    27181 ttgcccaact gcgctccact aattcttgca actccataat tagtatccta ataaaaaaat
    27241 gcgacatcct cgaaaggacg tcgcaacgtg gttccacctt catttatgta cctcaaaaga
    27301 gagggacacc tctgattggc tctaacgtgg ccaccgtttt atgttttcat aaaaaactca
    27361 agagtagtat cagtttagac ttcctatgcg tttccagcaa ccacgcactc tctagtagaa
    27421 agggactaag tgacttgtct ctatggatta ttatagcatg attgtgagat ttttcaagga
    27481 ttttgtgaaa gttttttgtt tttcattttt tgtagaatat gcttgatgct aataccagaa
    27541 tccatgccca ccagagcaac tgtttcatag attagcaagt aaattagtat aaactcacca
    27601 aaggttatga tagtaaagta aaagagcagt ccgttaccaa ctaaccatca aagtgagaaa
    27661 cggaaacggt agctatagag taacgataca atcaagatta ccagaggtgt aaagaagaga
    27721 agattgttta tatagagttc cttgagtgta agggggtcag aaacaactag taagaacaac
    27781 tcataaagtg gccaataaaa gaataatatg accagatagt aggggagatg ggaatagaat
    27841 ctacgcatga taatcacctc gttttaaaaa aacagacaac ttagatctct tgctatgatt
    27901 attatagcat gtttaaaaca agaaagtaaa tttgttggca aagaagattt ttttttcact
    27961 agaatcatgg ttagttttct tggtagaaat attttgataa taattaagca aaactattga
    28021 cattgattat taagagtgtc acaattgttg taactaaaat aattacaata agagaggtat
    28081 aaaaaatgaa actagcagtt attgcagcaa atggacaagc ggggaaagca attgttgaag
    28141 aagtagtcaa acgaggacat gaagtaacgg ctattgttcg ttctgaaaac aaaagtcaat
    28201 ctgagtctat tattaaaaaa gatttatttg agttgacaaa agatgatctt actggatttg
    28261 atgctgttat ttcagcgttt ggtgcttata caccagatac gctaccgctc cacagcaaat
    28321 caatcgaact atttaatcag cttcttgctg gaacacagac acgttttcta gttgtagggg
    28381 gagcaggaag tctttatata gatgaaacaa aaacgacacg acttttagat acgtctgatt
    28441 ttcctgaaga atttaagtca ctagcaaaag ctcaagcgga tgaattggat cttcttcgta
    28501 caaaaaataa tctcaactgg acttttgtca gtcctgctgt agattttatt cccgatggtg
    28561 aaaaaacagg aaactacatt ctagcaggag aaatttttac tactaatgaa aaaggaataa
    28621 gccagattag ttatgcagat tatgctattg gattggtaga tgaacttgaa aaaggtcatc
    28681 atataaaaga acgtatctct ttacttgaaa aataataact atgagagtat taatgtttga
    28741 cagaaaattt aaatcttggt aaaataggga ttgtcgtaaa gacaaataac ttcttcttgg
    28801 ttacaggcat gccaacctgt cactcggatg aagccaaata aaaaggagaa acatcatggc
    28861 aatctcaaaa gagaaaaaaa atgaaatcat tgcacaatat gcacgtcacg aaggtgatac
    28921 aggttcagta gaggttcaag ttgctgtcct tacttgggaa atcaaccacc ttaacgaaca
    28981 catcaaacaa cacaaaaaag accacgctac ttaccgtgga ttgatgaaaa aaatcggtcg
    29041 ccgtcgtaac ttgcttgcat acttgcgtaa aaacgacgtt aaccgttacc gtgagttgat
    29101 caactctcta ggacttcgtc gctaattcaa gatacaaagg ccgtcaaaaa cacaaagcaa
    29161 aaataggaaa attgacgaag aaacttcagt ttctaggaga ttttatcttt tttgccaagt
    29221 gcttaggccg tgttcaattg agcatatctt gataataaag ctactctaaa ttgggtagct
    29281 ttgttgcgtt gtcaccttac ctcgctatac tcaagtataa tcttcggtta cggttcctag
    29341 cactgtaagg taaaataaac tagcttttct cccttcgggg agattttttt gtttcactga
    29401 aagtttcgta cgatcttcac ctcgtcccct agtctataaa cgatttatct agcaagaatc
    29461 atgatgctaa gggcgtcaaa aatccgtatg aaaataggga aatgacacag tgttcgatga
    29521 gcacaaggag tttcatcttt ttcactagga ttttagcccg ggctaaaatc agctctctga
    29581 cttcagaggg cttttttatt gaggttttat cggtaacaat tttggagact acaaaaacct
    29641 caaatggtat cagctaatta caccataaag gtgcgcagtt actcggcttt tcaagccgag
    29701 tagctgtatg caagccccct agaagagccc actctttaca aagtaaagta tagtatgtta
    29761 tactttacat ggaagtagtc actgaattcc agttagaaat tactttgtaa ctacgttttg
    29821 aggaggagta aaatgctttc ctacgttcga cattacccac tagcgatagc taaattaatg
    29881 tgtctgtgct ctcctaaaat ctgctgattt attactgact aatacaggag gtttttttta
    29941 tgggacagac aatcatatct gctattggtg tttatatttc caccagtatc gattatttaa
    30001 ttattttaat tattttattt gcacagctat cacagaataa acagaaatgg catatttatg
    30061 cggggcaata tctaggcaca ggcttacttg taggggcgag tttagttgct gcttatgtcg
    30121 ttaatttcgt gcctgaagaa tggatggttg gattgcttgg tttaatccct atctatttag
    30181 ggattcgctt tgcaattgtt ggagaagatg cggaagaaga agaggaagaa attattgaaa
    30241 gattagaaca aagcaaggca aatcaactgt tttggacagt tacattgctg acaattgcgt
    30301 ctggcggaga taatttaggt atctatatac cttattttgc ttcgttagat tggtcacaga
    30361 ccctcgtggc cttgcttgtg tttgtaatcg gcataattat cttttgcgag attagtcggg
    30421 tgttatcctc tattccgtta atattcgaga caattgaaaa atacgagcga atcattgtgc
    30481 ccttagtatt cattctactt ggactataca tcatgtatga aaatggcacg atagagactt
    30541 ttctgatcgt gtagattttt ttgtttcact aggattttag cccgagctca aatcagctct
    30601 ctgattttca gggggctttt tcattgagta taaatggaca atcttaaagt tactctattg
    30661 tagagtggct tttgatttga ttaggagatt cttataaata tagtaaaatg aaataagaat
    30721 aggacaaatc gatcaggaca gtcaaatcga tttctaaaaa tgttttagaa gtagaggtgt
    30781 actattctag ttccaatcta ctatataaat gaaaacctta gctgtttggc caaggttcat
    30841 ttcttctatg caagttcttc tcttttctta tctgggttcc agatgaagct tgcgataaag
    30901 ctaaagatga tggttaggat agcgaggata atagcaagga tgagggcagg gatgcggata
    30961 aaccaccaga gtggatttgg ttttttatca ttgtgccatt gtttcgtttc ttcgtccaga
    31021 cgttggaatt ctgtttgaat acgattggcg actgtttcaa tgccttcatc attcattttc
    31081 ttgatatctg agatatcgat tggatttcca aagttcatat cgacacgttc acggctaatc
    31141 aagcccttca aagtcatggg accggtgtag gtaaccggca tgatacggac cttggccatt
    31201 ttggcaatca gtgctgcgcc ccccttgaca tcgtttgagt ggcggctacc acttggaaac
    31261 atgatgagag agcggtcact ttttttgaga acgttgatag gatatttgat ggctgaggcg
    31321 ctgggatttt cacggtcgat gggaaaggcg ccacacatac gaatccacca accaaagata
    31381 cggttggtaa agagttcttt ttttgccata aagatgaact gttttggctt ggtcgcaaag
    31441 gccatataaa caggatccca ccaggtacgg tgaggcgcaa ctaaaatata attttcatct
    31501 tgattaggaa ttttatcagt attatgatag tgagcattgc cattgatgga ccataagagc
    31561 aatacaacta atccacgcaa ataagtataa aacatgcgat ctccttcgat tgttttcttg
    31621 ttattattat accttatcaa aggagggctg gcaaactttt cccttgacta gatacatatt
    31681 taggatgaaa ttagaattct gttaaaaaaa atgatataat agaatttatg gataaaaata
    31741 agattatggg attaacccaa agagaagtca aggaaagaca ggctgagggt ttggtcaatg
    31801 actttaccgc atcagccagt accagcactt ggcaaatcgt taaacgaaat gtctttaccc
    31861 tttttaacgc tttgaacttt gccattgctt tggctcttgc ctttgtgcag gcttggagca
    31921 atctggtctt ctttgctgtt atctgcttta acgctttttc tgggattgtg accgagctac
    31981 gagccaaaca catggtggac aagctcaatc tcatgaccaa ggaaaaggtc aaaaccatcc
    32041 gtgatggtca ggaagttgct cttaatcctg aagaattagt gctaggagat gtcattcgtt
    32101 tgtctgcagg agagcagatt cctagtgatg ccttggtttt ggaaggcttt gcggaagtca
    32161 atgaagccat gttaacggga gaaagtgatt tggtgcaaaa ggaagttgac ggcttacttt
    32221 tgtcaggaag tttcctagcc agtgggtcag ttttatctca agttcaccat gtcggtgcag
    32281 acaactatgc tgccaaactc atgcttgagg ctaagaccgt taaacccatc aactcccgta
    32341 tcatgaaatc gctggacaag ttggctggtt ttactgggaa gattatcatt ccctttggtc
    32401 tggctctctt gctggaagcc ttgcttttaa aaggcctgcc tctcaagtca tccgttgtaa
    32461 actcgtcgac agctcttttg ggaatgttgc ctaagggaat tgcccttttg accattactt
    32521 cgctcttgac tgcagtgatt aagttgggct tgaaaaaggt cttggtgcag gagatgtact
    32581 ctgttgagac cttggcgcgc gtggatatgc tctgtctgga caagacgggt accatcaccc
    32641 aaggaaagat gcaggtggag gctgttcttc cgttgatgga aacgtatggt gaagaggcta
    32701 ttgccagcat cttgactagc tacatggccc atagtgagga taagaatcca actgcccaag
    32761 ccattcgcca gcgttttgtg ggagatgttg cttatcctat gatttccaat cttcccttct
    32821 cgagcgaccg caagtggggg gctatggagt tagaaggctt ggggacagtt ttcttagggg
    32881 cgcctgagat gttgctggat tctgaagtcc cagaagccag ggaggccttg gagagaggat
    32941 cacgtgtctt ggtcttagct ctcagtcagg agaaattaga ccatcacaaa ccacagaaac
    33001 catctgatat tcaggctcta gccttgctgg aaatcttgga ctccattcga gagggagcag
    33061 cagagacgct ggactatctc cgttctcagg aggtaggact caagattatc tctggtgaca
    33121 atccagttac ggtgtccagc attgcccaga aggctggttt tgcggactat cacaactatg
    33181 tagattgctc aaaaatcacc gatgaggaat tgatggccat ggcggaggag acagctattt
    33241 tcggacgtgt ttcccctcat caaaagaaac tcatcatcca aacgttgaaa aaagcgggtc
    33301 atacaacggc tatgacaggg gacggggtta atgatatctt ggcccttcgt gaggcggatt
    33361 gttctatcgt gatggcggag ggggatccag caacccgtca gattgccaat ctggttctct
    33421 tgaactcaga ctttaatgat gttcctgaga ttctcttcga gggtcgtcgc gtggtcaata
    33481 acattgccca catcgccccg attttcttga taaagaccat ctattccttc ctgttagcag
    33541 tcatctgtat tgccagtgct ttactaggtc ggtcagagtg gattttgatt ttccccttca
    33601 ttccgatcca gattaccatg attgaccagt ttgtggaagg tttcccacca ttcgttctga
    33661 cttttgagcg aaatatcaaa cctgttgagc agaatttcct cagaaaatcc atgcttcgtg
    33721 ccctaccaag cgctctcatg gtcgtcttta gcgtcctgtt tgtgaaaata tttgggagta
    33781 gccaaggttg gtctgagtta gaaatctcaa ctctcctcta ttatctcttg gggtcaattg
    33841 gtttcttatc cgtatttaga gcctgcatgc catttaccct atggcgtgtc ctcttgattg
    33901 tttggtcagt aggaggtttc ctagccacag ctctcttccc aagaatccaa aaactgcttg
    33961 aaatttcaac cttaacagga caaacattac ctgtttatgg tgtcatgatg ttggtcttta
    34021 ccgtgatttt catcctgacc agtcgctatc aagccagaaa ataaagaaag gctgcaatct
    34081 gtggattgca gtttttttag gtacaagatt gccagtcgaa atgtggtata ataagaggta
    34141 atagagtttt ggaaagtgag agaagatgat ttcaaagaga ttagaattgg tagcttcctt
    34201 tgtgtcacag ggggctattt tactagatgt gggaagtgac catgcttatc tgcctatcga
    34261 gttggttgag agaggccaaa tcaaaagcgc tattgcaggt gaggtggtgg aaggtcccta
    34321 tcagtctgcg gttaaaaatg ttgaggctca cggcctaaag gagaaaatcc aagtccgttt
    34381 agccaatggc ttggcagctt ttgaagagac tgaccaagtg tctgtcatta ccattgctgg
    34441 catgggtggt cgtttgattg ctaggatttt agaagaaggt ttggggaagt tagctaatgt
    34501 agagcgtttg atcctccagc ccaataatcg tgaagacgac ttgcgtatct ggctacagga
    34561 tcatggattc cagattgtag cagaaagcat tttagaagaa gctggaaagt tttatgagat
    34621 tttggtggtg gaagcaggac aaatgaagct atcagccagt gatgttcgct ttggtccctt
    34681 cttgtccaaa gaagtcagtc cagtatttgt ccaaaaatgg caaaaagaag ctgagaagct
    34741 agagttcgcc ctcggacaaa tcccagaaaa aaatctggaa gaacgtcaag ttctagtaga
    34801 taagattcaa gctatcaagg aggtgctcca tgttagcaag tgaagtgatc caagcttatg
    34861 aagccttttg ccctcaggaa ttttctatgg agggagacag ccgtggtctg caaattggca
    34921 ctttagacaa gggtatccaa agggtcatgg ttgccctcga tattcgtgaa gagacggtgg
    34981 cagaggctat tgaaaagggt gtggacttga ttatcgtcaa gcacgcgcct atctttcgtc
    35041 ctatcaagga cttgcttgcc agccgtccgc aaaatcagat ttacatcgac ctgattaagc
    35101 atgatatcgc agtttatgtc agccatacca atattgatat cgttgaaaat gggctcaatg
    35161 actggttttg tcagatgcta ggaatcgagg agacgactta tctgcaggaa acaggtccag
    35221 aacgtggaat tggacgtatt gggaatattc agcctcagac attttgggaa ttggcccaac
    35281 aggtcaagca agtctttgac ctagatagcc ttcgaatggt gcattatcaa gagaatgatt
    35341 tgcagaagcc tatttcaaga gtagcaattt gtggtggaag cgggcagtct ttctataagg
    35401 atgctttggc aaagggggca gatgtctata tcactggtga tatctactac catactgctc
    35461 aggatatgct gtctgatggc ttgttagcat tggatccagg tcactatatc gaagtgcttt
    35521 ttgtggaaaa aatcgcagca ctccttactc aatggaaaga gaaaaaaggc tgggaactag
    35581 agattttacc tagtcaagca tcgaccaatc ctttccgtca tatctagtta gaaagtgaag
    35641 acaatgaaaa aagttgccat tattggagca ggaattgtgg gagcaacagc tgcctactac
    35701 ctctcgagag aaagtgacct agaggtgacc gtttttgacc atgagcaagg tcaagccacc
    35761 aaggccgcag caggaattat cagtccttgg ttttccaaac gccgtaataa agcctggtac
    35821 aagatggcgc gcttgggggc tgatttttat gtggatttat tagctgattt agagaaatca
    35881 ggacaagaaa tcgactttta ccagcgttcg ggagtctttc tcttgaaaaa ggatgaatcc
    35941 aagttggaag aactctatca actggctctc cagcgcagag aagaatctcc cctgataggc
    36001 cagttagcca ttctggatca agcatcagct aatgaattat tccctggctt gcagggattc
    36061 gacaacttgc tctatgcttc tggtggagcg agagtagatg gccaactctt ggtaactcgt
    36121 ctgctagaag ccagtcatgt caagttggtc aaagaaaaag tgactctgac actcttatca
    36181 tcaggctacc agattggcga agaggtgttt gatcaggtta ttttggcaac gggagcttgg
    36241 ttgggggaca tgttagaacc tttaggttat gaagtggatg tccgtcctca aaaaggacaa
    36301 ctacgagatt atcagcttgc ccaagacatg gaagattacc ctgttgtcat gccagaaggg
    36361 gagtgggatt tgattccctt tgcaggtggg aaattatcct tgggcgctac ccatgaaaat
    36421 gacatgggat ttgatttgac ggtagatgaa cccttgctcc aacaaatgga ggaggcggcc
    36481 ttgcctcatt acccagtttt agctagagtg acttcaaggg ctgagcgtgt gggaatccgt
    36541 gcctatacca gtgatttctc tcccttcttt gggcaggtgc cagaattggc aggtgtctat
    36601 gcagccagtg gactaggttc atcaggcctc acaactggtc ctatcattgg ttaccatcta
    36661 gcccaactga tccaagacaa ggagttgacc ttggaccctc taaattaccc aattgaaaac
    36721 tatgtcaaac gagtaaaaag cgaataatac tcaatgaaaa tcaaagaaca aactaggtaa
    36781 ctagccgcgg gttactcaaa gcactgcttt gaggttgtgg atagaactga cgaagtcagc
    36841 tcaaaacact gttttgaggt tgtggataga actgacgaag tcagtaacca tacccatggc
    36901 aaggcgacgt tgacgtggtt tgaattggat tttcgaagag tataagcatt ttactgaaat
    36961 tttatcaggt agtttaggat ggcaaatgac attccctgtc aaaaatggta aaataagaaa
    37021 aaataatctg agaatcgagg aaaaaagatg caagaaaaga ttttggtaac tggtggtgcc
    37081 ggttttattg gaacccacac tgttattgaa ttgatccaag caggccatca agttgttgtg
    37141 gtggataatc ttgtcaatag caatcgtaag agtttagaag ttgttgaaag aatcacagga
    37201 gttgagattc ctttctatga ggcagatatt cgtgacacag ctaccctcag agatattttc
    37261 aagcaggaag aaccgactgg tgtcattcac tttgctggtt tgaaggctgt tggcgaatca
    37321 acacgtatcc ctcttgccta ctatgacaac aatatcgctg gaactgtcag ccttttgaaa
    37381 gccatggaag aaaacaactg taaaaacatc atcttcagtt cttctgcgac agtttacggg
    37441 gatccgcaca cagtgcccat cttggaagat ttcccacttt cagtgaccaa cccatacggt
    37501 cgtactaagc tcatgctaga ggaaattttg actgatattt acaaagcaga ctcagaatgg
    37561 aatgttgtct tgcttcgtta ctttaaccca atcggagccc atgagagtgg tgatttggga
    37621 gaaaatccaa acggtattcc aaacaatctc ttgccatatg tgactcaagt agccgttgga
    37681 aaattagagc aagtgcaagt gtttggagac gattacgata cggaagatgg aacaggtgtt
    37741 cgtgactata tccacgttgt cgatttggct aagggtcacg ttgcagcttt gaaaaaaatc
    37801 caaaaaggtt caggactaaa cgtttataac cttggaactg gtaaaggtta ctcagttctt
    37861 gaaattatcc aaaacatgga aaaagcggtg ggccgtccta ttccttaccg catcgtagaa
    37921 cgtcgcccag gtgatatcgc tgcctgctac tcagacccgg caaaagctaa agcagaactc
    37981 ggttgggaag cagaactcga catcacccaa atgtgtgaag acgcatggcg ttggcaaagc
    38041 aagcatccaa atggatttga agactaagat gatgatttca atcatcgtcc cttgtttaaa
    38101 cgaagaggaa gtacttcctc ttttttatca ggctctggaa gctttacttc cagatttgga
    38161 aacagaaatc gagtatgtct ttgtcgatga tggatcaagt gatgggacct tggaactctt
    38221 aaaggcctat cgggagcaaa atccggcagt ccattatatt tctttctctc gaaattttgg
    38281 caaagaagca gccctttatg caggcttgca atatgcgaca ggagatttgg tggtggtgat
    38341 ggatgcagac ctccaagatc ctcctagtat gttgtttgag atgaaaaatg tactagacaa
    38401 aaatgtagac ttggactgcg ttgggacacg gagaactagt cgggagggag aacccttctt
    38461 tcgcagtttc tgtgctgttc tcttttatcg cctcatgcaa aaaatcagcc cagtagctct
    38521 gccgtcgggt gtccgtgatt ttcgtatgat gagaaggtct gtagtcgatg ccattttaag
    38581 cttgaccgag tccaatcgtt tttcaaaggg gctcttcgcc tgggtgggtt tcaaaaccta
    38641 ctatttggac tatccaaatg tcgaaaggca ggctggcaag accagttgga gttttaggca
    38701 actctttttt tactccattg aagggattgt taatttttca gatttccctt tgactatagc
    38761 ctttgtagct ggtctcctat cttgttttct ttctctgctg atgacctttt ttgttgtggt
    38821 tcggaccctc attttgggca atccgacatc tggttggacc tctctgatgg ctgttattct
    38881 ctttcttgga ggcattcaac tcttgaccat tgggattctc ggtaagtata tcagtaagat
    38941 ttatttagag actaaaaaaa gaccacttta tcttatcaaa gaaaaaagtg accttcctga
    39001 ttttacagaa aaaataaagt gaaaagacta taattttaca tggaaatgtg ctaaactaga
    39061 gggagtggat tatcgccatt gatttaggct tcctggtttc caatcagggc gcgagttggg
    39121 caatttttaa cagcctctaa gacatcctga ctaggagaaa tttctttttc cagttggtca
    39181 gggtcatcgt aaaaacgcac gattccatta tcgtggtaat caaataaatc agaataagtt
    39241 tggcaaagtc cacaggcgat acatcgttca ggtataagtg tgattttcat gttcatattt
    39301 atattgtaat aagaaaagta aaaaaaaaca aggagtaagg tatggcaaaa gaaccgtggc
    39361 aagaagatat ttatgatcaa gaagaatcaa gagcagggcg tcggcatcga aaccacggag
    39421 gggctgatag gatggctaat cgtattttga cgatcctagc tagtattttc tttgtaattg
    39481 tggtggtgat ggtcatcgtt ctcatctatc tatcatcggg ggggagtaat cgcacagcag
    39541 ccttaaaaga ctttcatgat tctgatgcaa gtgtagtaca aatctcatct tcaagcagtt
    39601 ctcagcctga gcagagttca gagccagaat ctacttctag tagttcagaa gaagctgcta
    39661 atcctgaagg aacgattaaa gttctcgcag gagaagggga agcagctatt gccgctcgtg
    39721 caggaatctc cattgctcag ttagaggcct tgaatcctgg gcacatggct acaggatctt
    39781 ggtttgctaa tccaggtgat gttataaaaa taaaatagga gccgatatga aaacaattca
    39841 aattgctatt gatggtcctg cttccagcgg taagagtacg gtcgcaaaga ttattgctaa
    39901 ggattttggg ttcacctacc ttgatacagg agctatgtat cgtgcagcga cctatatggc
    39961 tcttaagaac caattaggag ttgaagaagt cgaagccctt ctagccttgt tggaccagca
    40021 tccaatcagc tttggacgtt cagaaactgg agaccagctt gtttttgtag gagatgtgga
    40081 tattacccat cctatccgtg aaaatgaagt gaccaatcat gtttctgcta ttgcagcaat
    40141 tcctgaagtg cgtgagaaac tggtttctct ccaacaagaa attgcccagc aaggcgggat
    40201 tgtcatggat ggtcgcgata ttggaactgt tgtattgcca caagcagaat tgaaaatttt
    40261 cctagtagct tctgttgatg agagagcaga gcgtcgttac aaggaaaata ttgccaaggg
    40321 aattgaaaca gaccttgaaa ccctaaaaaa ggaaattgct gcgcgtgact acaaggatag
    40381 tcatcgtgag acttctcctc tcaaacaagc agaggatgct gtctaccttg atacaactgg
    40441 tttgaacatt caagaagtag ttgaaaaaat caaagcagaa gctgaaaaaa gaatgtaaat
    40501 gtagaaaagc cgatagattg atatcggttt ttttctaaat ttgtcaaaat gctgatttta
    40561 gggtataata gttgctgttc gagaaatttt gattttcaaa gaatagtgaa tgatgataag
    40621 gagaaaccat gaacaattta ccaaattgtc caaaatgtaa ctcagagtat gtctacgaag
    40681 acggtgccct actggtttgc ccagagtgtg ctcatgagtg gaatcctgct gaagttgcag
    40741 aagtagaaga aggtcttgtc gctatcgatg ccaacggaaa taaattgact gatggtgata
    40801 cagtaactct catcaaggac ttgaaagtaa aaggtgcgcc aaaagatttg aaacaaggga
    40861 cgcgcgtgaa aaatatccgc atcgtagaag gcgatcacaa tatcgactgt aagattgatg
    40921 gttttggtgc catgaaactt aaatcagagt ttgtgaggaa gatttaagca tgtcaaaaca
    40981 ctataaactt gtattttata gccgtatctt cttgtttcta gcggctttta cgggagttta
    41041 tcttgaaatt actaggcatg gtggttttgg gatgcttctc tattacacgg ttctgtccaa
    41101 cctcttggta actattttta ccctttatct tctaaaggtt atgagccgtg taggtgaaaa
    41161 ttggcaaagg ccaagtctct tgcgcttaaa aggtggggtc accatgagta tcatgattac
    41221 ctgtgtgatt taccatttcc tcttggcgcc cattgcgact aatttctata ccctagaaaa
    41281 tttcctttgc cactatatcg ttcccatctg gtttttagcg gataccctct tttttgacaa
    41341 acagggtcaa tacaagattt gggatccagc agtgtggacc attttaccct ttctgtatat
    41401 gatgtttgct ctttttaatg gcttggttct aaaactcaat attccaaatg ccaaggataa
    41461 tcctttccct tacttctttt tgaatgtgaa caagggttgg aatgttgtgt ttaagtggtg
    41521 tctgattatc tttgttgcct atatggtagc aggatttatt ttctacttta tcaagcaaat
    41581 caagagaaag tcatcctaat actcttcgaa aatctcttca aaccacgtta gtttccatct
    41641 gcaacctcaa aacactgttt tgaacaacct gcggctagct ttctagtttg ctctttgatt
    41701 ttcattgagt atgagataca agggattcat tttcgaattt aagaaggagt ctacaaacca
    41761 atgaggcttc ttcttttctt gcttatttga taactatcaa aaaagtagaa gattaagaga
    41821 aatatagaaa gagatttcat gaaacaattt ttagaacggg ccagcatttt ggctctctcc
    41881 ctcgttttga ttacctcctt ttccatttcg agtgccctac cagccatgtt tgactattat
    41941 cagggttatt ctaaggaaca aattgagctc ttggtgagct tgccttcctt tggaatcatg
    42001 atgatgttac tgctaaatgg tttcttagaa aaaatatttc ctgagcgctt acagattagt
    42061 ttgggcttgc tgattttatc attgagcggt acagctccct tctggtacca agcctatccc
    42121 tttgtctttg gaacacggct tctctttggt ttgggtcttg ggatgatcaa tgccaaggcc
    42181 atttctatta tcagtgaacg ctaccaagga aaaaggcgaa ttcagatgtt agggctacgc
    42241 gcttctgcag aggtcgttgg agcttctctc attaccttgg ccgtcggtca gttgttggcc
    42301 tttggttgga cagctatctt tctagcctat agtgctggat ttttggtgat gcccctttat
    42361 ctgctctttg tcccttatgg aaaatcaaag aaagaagtca agaaaagagc gaaggaagca
    42421 agtcgtttaa ctcgagaaat gaaaggcttg atttttacct tagctatcga agcggcagtt
    42481 gtagtttgta ccaatacagc tattaccatc cgtattccaa gtttgatggt ggaaagagga
    42541 ttgggggatg cccagttatc tagttttgtt cttagtatca tgcagttgat cgggattgtg
    42601 gctggggtga gtttttcttt cttgatttct atctttaaag agaaactgct cctctggtct
    42661 ggtattacct ttggcttggg gcaaatcgtg attgccttgt cttcatcctt gtgggtggta
    42721 gtagcaggaa gtgttctggc tggatttgcc tatagtgtag tcttgacgac ggtctttcaa
    42781 cttgtctctg aacgaattcc agctaaactc ctcaatcaag caacttcatt tgctgtatta
    42841 ggctgtagtt tcggagcctt tacgacccca tttgttctag gtgcaattgg cttactaact
    42901 cacaatggga tgttggtctt tagtatctta ggaggttggt tgattgtaat ctctatcttt
    42961 gtcatgtacc tacttcagaa gagagcttag gattgattcc taagtttttc ttttgatact
    43021 caatgaaaat caaagagcat agttgattga gtttggaata gtacgctgta gctgctaaaa
    43081 tatttctaga aattaatttg acttttctaa tagagttatt catatcttat ttcaatctac
    43141 tatagaaagc tagccgcagg ttgctcaaaa tagtgttttg aggttgcaga tggaaactga
    43201 cgtggtttga agagattttc gaagagtatg agatttttat acccatacaa tatttgtttt
    43261 aggtccttgt ttacagacta atttcttgat aaaatagagg ttatgacgag atataaagca
    43321 actatttcct atgatggtta tgcctttgct ggctttcagc gccagtctca tgcgcgtagc
    43381 gttcaggaag aaattgaaaa aaccttgacc agattaaata aagggcaaac cattactgtt
    43441 cacggtgctg gtaggacaga tagtggggtt catgccctgg gacaggtcat tcattttgac
    43501 ctgccttatc agatggatga ggagaaactc cgttttgcct tggataccca gtctcctgaa
    43561 gatattgatg tgatttcgat tgagcttgtg gcagatgatt ttcattgccg ttatgccaaa
    43621 catagcaaga cctatgagtt tattgtggat agaggacgtc ccaaaaatcc tatgcgccgt
    43681 cactatgcca cccactttcc ctacccactc gatgtggaac gaatgcagat tgcaatcaaa
    43741 aagctagagg gaacccatga ttttaccggt tttacagcct ctgggactag tgtagaggat
    43801 aaggttcgca ccatcacaga agctagttta atagtcgatg agacaggaca atttttgacc
    43861 tttacctttt caggaaatgg tttcttgtat aaacagattc gcaatatggt ggggactctt
    43921 ctcaaaatcg gtaacaaccg catgccagta gagcagattg atctcatctt ggagaagaag
    43981 gacaggcaac ttgcaggtcc cactgcagca ccaaatggtt tgtatttaaa ggagattcgt
    44041 tatgaagaat aatcgtattt tagcactttc tggaaatgat atttttagtg gtggtggact
    44101 gtcagctgat ttggctacct ataccttgaa cggcttgcat gggtttgtag cagtgacttg
    44161 tttgacagcc ttgacagaaa aaggatttga agtctttcca actgatgata ccatttttca
    44221 acatgaatta gatagcttac gtgatgtgga atttggggga attaagattg gtcttctccc
    44281 tactgtcagt gtggctgaga aggccttgga ctttatcaaa caacgcccag gagtacctgt
    44341 ggtgttggat cctgtcttgg tctgcaagga aacgcatgat gtagctgtca gtgagctctg
    44401 ccaagagttg attcgctttt tcccttatgt cagtgtgatt acgcctaatc tcccagaagc
    44461 agaattatta tccggtcagg aaattaaaac cttggaagac atgaaaactg cagcgcagaa
    44521 attgcatgat ttaggagcgc cagcagtcat tatcaaggga ggcaatcgtc ttagtcagga
    44581 caaggctgtg gatgtctttt atgatggaca gacctttact atcctagaaa atccagttat
    44641 ccaaggccaa aatgctggtg caggttgtac ctttgcctct agcattgcca gtcacttgat
    44701 taaaggtgat aaacttttgc cagcagtaga aagctctaag gctttcgttt atcgtgctat
    44761 tgcacaagca gatcagtatg gagtaagaca atatgaagca aacaaaaaca actaaaatcg
    44821 cccttgtatc cctattaacc gccctttctg tggttctagg ttatttctta aaaatcccaa
    44881 cacctacagg aattctaact cttttagatg ctggtgtctt ctttgcggcc ttttactttg
    44941 gtagtcgtga aggagcggta gtcggaggac tagcaagttt cttgattgac ctcttatcag
    45001 gctaccctca gtggatgttc tttagcttgg tcaaccatgg cttgcaggga tttttcgcag
    45061 gatttaaagg aaaaagtcag tggttaggcc ttattttagc aactattgcc atggtaggag
    45121 gctacgcctt gggttctact ttgatgaatg gctgggcagc agccctccca gaaattctac
    45181 caaatttcat gcaaaatatg gtagggatga ttgtaggatt tattcttagt caaagtatca
    45241 agaagattaa gtaatactct tcgaaaatct cttcaaacca cgtcagcttc catctgcaac
    45301 ctcaaaacac tgttttgagc agcctgaggc tagctttcta gtttgcactt tgattttcat
    45361 tgagtataaa gaggttgagt aaaaagtatt tcaaataaga aaaacgcata gtatcaggtg
    45421 ttgaatgaac tgccccccaa aagttagaca gaaaaaatct aacttttggg gtgttttatt
    45481 atgaaactaa cttatgatga taaagttcag atctatgaac ttagaaaaca aggatatagc
    45541 ttagagaagc tttcaaataa atttgggata aacaattcta atcttaggta catgattaaa
    45601 ttgattgatc gttacggaat agagttcgtc aaaaaaggga aaaatcgtta ctattctcct
    45661 gatttaaaac aagaaatgat tcataaagtc tgacatgaag gctagactaa agatagagtt
    45721 tctcttgaat acggtctccc aagtcgtacg atacttctta actggctagc acaatacagg
    45781 aaaaacgggt atactattgt tgagaaaaca agagggagag tacctaaaat gggacgtaag
    45841 ccaaaaaaga gacctgaaga gaggacagaa ttagaacgtc ttcaagcaga aaatgagtac
    45901 ctgagagcgg agaatgccat cctaaaaaag ttaagagaac tccgattgaa ggaggaaaaa
    45961 gagaaagaca gaaattgttt aagaattaat gactgagttt tcgttagatc ttcttctaaa
    46021 agccattaaa ctagctcgtt cgacctacta ctatcacttg aaacagctag acaaaacaga
    46081 taaggaccaa gagcttaaag ctgaaattca atccattttt atcgaacaca agggaaatta
    46141 tgcttatcgt cgaattcatt tagaactaag aaatcgtggt tatctggtaa atcataaaag
    46201 agttcaaggc ttgatgaaag tactcaattt acaagctaaa atgcgacaga aacgaaaata
    46261 ttcttctcat aaaggagacg ttggtaagaa agcagagaat ctcattcaag gccaatttga
    46321 aggctctaaa acaatggaac agtgctacac agatgtgact gaatttgcca ttccagcaag
    46381 tactcaaaag ctttacttat caccagtttt ag
//
LOCUS       DAVHTH010000012        45755 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.012, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000012 DAVHTH010000000
VERSION     DAVHTH010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 45755)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45755)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45755
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.012"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            complement(178..981)
                     /locus_tag="VVR63_000674"
     CDS             complement(178..981)
                     /locus_tag="VVR63_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic/DOC family protein"
                     /protein_id="HEU6128715.1"
                     /translation="MQSTYNIDNPNLSYEAKRDLWRIGFGLQKVDNLVPSAYMESLAE
                     KQSRGELTYEQVYEDATAYHHTIDASTEEADLVSLRIVELLSRRGFSFSPATLLAIHK
                     ELFQDIFEPSIPVGQFRQTNITKNEPVLNGESVVYSDYSMIQMTLDYDFNQEKQVAYA
                     TLTQADVVKQIQHFISGIWQIHPFREGNTRTVTVFLIQYLREFGFDIDNIPFQQHSKY
                     FRDALVLDNAKILQRRPEFLTAFFENLLLGGQNDLSSEKMYLDLDLDFS"
     gene            complement(1260..2015)
                     /locus_tag="VVR63_000675"
     CDS             complement(1260..2015)
                     /locus_tag="VVR63_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3883 domain-containing protein"
                     /protein_id="HEU6128716.1"
                     /translation="MSKHPHYELLNLIGYGLAKFDKLFIKEFQCSSKSEFYRYVVSLE
                     IAETTGVVKNRMDLFDPYFDNNRKGWWQKAEVYRFRKDLIDMMFGNEDVHSYAEIVKM
                     LLASEGKKTGITIVEKPIVRTKFKRLQETGMEAENYFILHFDKEEKFQGGQLTDARLY
                     GDGYDFQVDVQEYSYLAEVKGIRKSKGRVRLTAKEFEKVKEFQSDFILSLVTNLDDIP
                     KLVLIDNPLKHFEFKKNIIKNEIIEYRSVEDLY"
     gene            complement(2085..4736)
                     /locus_tag="VVR63_000676"
     CDS             complement(2085..4736)
                     /locus_tag="VVR63_000676"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HEU6128717.1"
                     /translation="MSKELSSKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLRGEG
                     ISRYDLGRESFLTKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVF
                     VDLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALEVAT
                     TRPETMFGDVAVAVNPEDPRYKDLIGKNVILPIANKLIPIVGDEHADPEFGTGVVKIT
                     PAHDPNDFLVGQRHNLPQVNVMNDDGTMNELAFEFSGMDRFEARKAVVAKLEEIGALV
                     KIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTEDKVEFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNADGEMYVGEEAPEGDGWTQDEDVLDTWFSS
                     ALWPFSTMGWPEVDSEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVL
                     IHGLIRDEQGRKMSKSLGNGIDPMDVIEKYGADALRWFLSNGSAPGQDVRFSYEKMDA
                     SWNFINKIWNISRYILMNNGGLTLDVAHDNVTKVATGEAGNVTDRWILHNLNETIAKV
                     TENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEDDKVITRSVLLYTLDKI
                     LRLLHSIMPFVTEEIFGQYAEGSIVTAAYPTVNPVFEDLAAHTGVESLKDLIRAVRNA
                     RAEVNVAPSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPEHLEIASTIPAPELAMSS
                     VITGAEIFLPLVDLLNVEEELARLEKELAKWQKELDMVGKKLSNERFVANAKPEVVQK
                     ERDKQADYQAKYDATVARIDEMKKLVK"
     gene            complement(4729..5307)
                     /locus_tag="VVR63_000677"
     CDS             complement(4729..5307)
                     /locus_tag="VVR63_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000550018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEU6128718.1"
                     /translation="MHLFIIGAPASGKMTIGQELSRLTDATLFYNHQAIDFALEIYQD
                     YTEEMWEFVRGITFSFLGASARNQRSVILTDVIDFSNQYHLIYLKQIQSLLDDYHQEI
                     LFVELETSLEECIRRNRTENRLKYKPLKRHIEVSEREIIETAETLQLNSQYQPNELHH
                     YFKINNTNLSAEEAAKQIQNKINKIEKGHTHV"
     gene            complement(5307..5867)
                     /locus_tag="VVR63_000678"
     CDS             complement(5307..5867)
                     /locus_tag="VVR63_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000124561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6128719.1"
                     /translation="MARTELPDKIETERLVLRVRTVADAEDIFDYASLPEVAYPAGFP
                     PVKTLEDEIYYLEHILPERNQKENLPAGYGIVVKGTDKIVGSIYFNHRHEDDVMEIGY
                     TLHSDYWGRGYVPEAARALIDLAFKDLGLHKIELTCFGYNLQSQRVAEKLGFTLEARI
                     RDRKDAQGNCCDDLRYALLKSEWEVI"
     gene            complement(5854..6303)
                     /locus_tag="VVR63_000679"
     CDS             complement(5854..6303)
                     /locus_tag="VVR63_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase"
                     /protein_id="HEU6128720.1"
                     /translation="MIGVVARENAAEQIKQYQKFTVNISDETSMLAMEQAGFISHQEK
                     LERLGVHYEISERTQIPILDACPLVLDCRVDRIVEEDGICHIFAKILERLVAPELLDE
                     KGHFKNQLFAPTYFMGDGYQRVYRYLDKRVDMKGSFIKKARKKDGKN"
     gene            complement(6715..7110)
                     /locus_tag="VVR63_000680"
     CDS             complement(6715..7110)
                     /locus_tag="VVR63_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEU6128721.1"
                     /translation="MSKKLNRKKQLRNGLRRAGAFSSTVTKVVDETKKVVKRAEQSAS
                     AAGKAVSKKVEQAVEATKEQAQKVANSVEDFAANLGGLPLDRAKTFYDEGIKSASDFK
                     NWTEKELLDLKGIGPATIKKLKENGIKFK"
     gene            complement(7206..7460)
                     /locus_tag="VVR63_000681"
     CDS             complement(7206..7460)
                     /locus_tag="VVR63_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HEU6128722.1"
                     /translation="MSYEQEFMKEFEAWVNTQIMINDMAHKESQKVYEEDQDERAKDA
                     MIRYESRLDAYQFLLGKFENFKAGKGFHDLPEGLFGERNY"
     gene            complement(7470..8804)
                     /locus_tag="VVR63_000682"
     CDS             complement(7470..8804)
                     /locus_tag="VVR63_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000752887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF438 domain-containing protein"
                     /protein_id="HEU6128723.1"
                     /translation="MTDERIHILRDILLELHNGASPESVQDRFDATFTGVSAIEISLM
                     EHELMNSDSGVTFEDVMELCDVHANLFKNAIKGVEVSDTEHPGHPVRVFKEENLALRA
                     ALIRIRRLLDTYESMEDEEMLAEMRKGLVRQMGLVGQFDIHYQRKEELFFPIMERYGH
                     DSPPKVMWGVDDQIRELFQTALTTAKSLPEVSISSVKEAFEAFATEFESMIFKEESIL
                     LMILLESFTQDDWLQIAEESDAYGYAIIRPSEKWVPERQSFIEEKIAEEPVQLDTAEG
                     QVQQVIDTPEGHFTITFTPKEKEAVLDRHSQQAFGNGYLSVEQANLILNHLPMEITFV
                     NKEDIFQYYNDNTPADEMIFKRTPSQVGRNVELCHPPKYLDKVKTIMKGLREGSKDKY
                     EMWFKSESRGKFVHITYAAVHDEDGEFQGVLEYVQDIQPYREIDTDYFRGLE"
     gene            complement(8804..9037)
                     /locus_tag="VVR63_000683"
     CDS             complement(8804..9037)
                     /locus_tag="VVR63_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006144975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1858 domain-containing protein"
                     /protein_id="HEU6128724.1"
                     /translation="MDNIIDVSIPVAEVVDKHPEVLEILVELGFKPLANPLMRNTVGR
                     KVSLKQGSKLAGTPMDKIVRTLEANGYEVIGLD"
     gene            complement(9497..9679)
                     /locus_tag="VVR63_000684"
     CDS             complement(9497..9679)
                     /locus_tag="VVR63_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6128725.1"
                     /translation="MNPIKAFAKIYGNYFLTVQGVKVMKTIKKADHVVVGLGKLFIAD
                     KLMDTARWLIKPEERE"
     gene            complement(9681..10460)
                     /locus_tag="VVR63_000685"
     CDS             complement(9681..10460)
                     /locus_tag="VVR63_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6128726.1"
                     /translation="MAEQDLAMQVLQQVVKLPVVKVDRSKFLVDKFSKELDPKDIPTL
                     LEQGTTTLLSQEILDRVANACIRDNVLLASGTSVLAGLAGWLAMAITIPADVAQFYAF
                     SLKLAQELGYIYGYEDLWASREELSEDAQNTLLLYLGVMLGVNGTAALLRAGGITIAK
                     QVMKTVPNKALTKTLWYPILKKVLRIFGVNLTKGGLAKGIGKFIPILGGIISGGLTFA
                     TMKPMGESLQKELSKLVNYSEVQYQEDVETIRKEAEIIKGE"
     gene            complement(10739..11089)
                     /gene="rbfA"
                     /locus_tag="VVR63_000686"
     CDS             complement(10739..11089)
                     /gene="rbfA"
                     /locus_tag="VVR63_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HEU6128727.1"
                     /translation="MANHFRTDRVGMEIKREVNEILQKKVRDPRVQGVTITDVQMLGD
                     LSVAKVYYTILSNLASDNQKVQIGLEKATGTIKRELGRNLKLYKIPDLTFVKDESIEY
                     GNKIDEMLRNLDKN"
     gene            complement(11340..14132)
                     /gene="infB"
                     /locus_tag="VVR63_000687"
     CDS             complement(11340..14132)
                     /gene="infB"
                     /locus_tag="VVR63_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HEU6128728.1"
                     /translation="MSKKRLYEIAKELGKESKEVVARAKELGLDVKSHSSSVEEAVAT
                     KIAASFKPAAAPKVEAKPAAPKVSAEKKAEKSEPAKPAVAKEEAKPAEPVAPKTEKVA
                     VKPQSRNFKAEREARAKEQAERRKQNKGNNRDQQQNGNRQKNDGRNGGKQGQSNRDNR
                     RFNDQAKKQQGQQKRRNERRQQEDKRSNQAAPRIDFKARAAALKAEQNAEYARSSEER
                     FKQYQAAKEALAQANKRKEPEEIFEEAAKLAEQAQQVQAVVEVVPEKKEPAVDTRRKK
                     QARPDKNRDDYDHEEDGPRKQQKNRSSQNQVRNQKNSNWNNNKKNKKGNNKNNRNQTP
                     KPVTERKFHELPTEFEYTDGMTVAEIAKRIKREPAEIVKKLFMMGVMATQNQSLDGET
                     IELLMVDYGIEAKQKVEVDNADIERFFVEDGYLNEDELVERPPVVTIMGHVDHGKTTL
                     LDTLRNSRVATGEAGGITQHIGAYQIVENGKKITFLDTPGHAAFTSMRARGASVTDIT
                     ILVVAADDGVMPQTIEAINHSKAANVPIIVAINKIDKPGANPERVIGELAEHGVMSTA
                     WGGDSEFVEISAKFNQNIEELLETVLLVAEIQELKADPTVRAIGTVIEARLDKGKGAV
                     ATLLVQQGTLNVQDPIVVGNTFGRVRAMTNDLGRRVKVAGPSTPVSITGLNEAPMAGD
                     HFAVYEDEKSARAAGEERAKRALMKQRQATQRVSLENLFDTLKAGELKSVNVIIKADV
                     QGSVEALSASLQKIDVEGVKVTIVHSAVGAINESDVTLAEASNAFIVGFNVRPTPQAR
                     QQAEADDVEIRLHSIIYKVIEEMEEAMKGMLDPEFEEKVIGEAVIRETFKVSKVGTIG
                     GFMVINGKVARDSKVRVIRDGVVIYDGELASLKHYKDDVKEVTNGREGGLMIDGYNDI
                     KMDDVIEAYVMEEIKR"
     gene            complement(14149..14448)
                     /locus_tag="VVR63_000688"
     CDS             complement(14149..14448)
                     /locus_tag="VVR63_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HEU6128729.1"
                     /translation="MNKQKISNLLGLAQRAGRIILGEELVVKAIQDGKAKLVFLAHDA
                     GPNLTKKIQDKSHYYQVEIVTVFSTLELSIAVGKSRKVLAVTDAGFTKKMRSLME"
     gene            complement(14441..14734)
                     /locus_tag="VVR63_000689"
     CDS             complement(14441..14734)
                     /locus_tag="VVR63_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HEU6128730.1"
                     /translation="MKTRKIPLRKSVVSNEVIDKRDLLRIVKNKEGQVFIDPTGKANG
                     RGAYIKLDNAEALEAKKKKVFNRSFSMEVEESFYDELIAYVDHKVKRRELGLE"
     gene            complement(14756..15892)
                     /gene="nusA"
                     /locus_tag="VVR63_000690"
     CDS             complement(14756..15892)
                     /gene="nusA"
                     /locus_tag="VVR63_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HEU6128731.1"
                     /translation="MSKEMLEAFRILEEDKGIKKEDIIDAVVESLRSAYRRRYGQSDS
                     VAIDFNEKTGDFTVYTVREVVDEVFDSRLEISLKDALAINSAYELGDKIKFEEAPAEF
                     GRVAAQSAKQTIMEKMRKQTRAITYNTYKEHEQEIMSGTVERFDNRFIYVNLGSIEAQ
                     LSKQDQIPGEVFASHDRIEVYVYKVEDNPRGVNVFVSRSHPEMIKRLMEQEIPEVYDG
                     TVEIMSVAREAGDRTKVAVRSHNPNVDAIGTIVGRGGANIKKITSKFHPARYDAKNDR
                     MVPIEENIDVIEWVADPAEFIYNAIAPAEVDQVIFDENDSKRALVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEFEAMEDAASVELEVENDTVEE"
     gene            complement(15936..16415)
                     /gene="rimP"
                     /locus_tag="VVR63_000691"
     CDS             complement(15936..16415)
                     /gene="rimP"
                     /locus_tag="VVR63_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HEU6128732.1"
                     /translation="MDAIATIVELVREVVEPVIEAPFELVDIEYGKIGSDMILSIFVD
                     KPEGITLNDTADLTEMISPVLDTIKPDPFPEQYFLEITSPGLERPLKTKDAVAGAVGK
                     YIHVGLYQAIDKQKVFEGTLLAFEEDELTMEYMDKTRKKTVQIPYSLVSKARLAVKL"
     gene            complement(16541..17176)
                     /gene="trmB"
                     /locus_tag="VVR63_000692"
     CDS             complement(16541..17176)
                     /gene="trmB"
                     /locus_tag="VVR63_000692"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001266107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HEU6128733.1"
                     /translation="MRVRNRKGATELLEANPQYVVLNPLEAKAKWRDLFGNDNPIHVE
                     VGSGKGAFVSGMAKQNPDINYIGIDIQKSVLSYALDKVLEVGVPNIKLLWVDGSDLTD
                     YFEDGEIDRLYLNFSDPWPKKRHEKRRLTYKTFLDTFKRILPENGEIHFKTDNRGLFE
                     YSLVSFSQYGMKLNGVWLDLHASDFEGNVMTEYEQKFSNKGQVIYRVEAEF"
     gene            complement(17173..17967)
                     /locus_tag="VVR63_000693"
     CDS             complement(17173..17967)
                     /locus_tag="VVR63_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000363010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HEU6128734.1"
                     /translation="MDLGDNELTLTPIPGKSGKAYMGSYPDGKRIFVKMNTSPILPGL
                     AREQIAPQLLWSRRLADGRDMCAQEWLTGKILTPYDMNRKQIVNILTRLHRSRPLMTQ
                     LSRLGYAMETPVDLLQSWQETAPDALRKNHFISEVMADLRQTIPGFREDHATIVHGDV
                     RHSNWIETDSGLIYLVDWDSVRLTDRMFDVAHMLCHYISEHQWKEWLTYYGYKYNQTV
                     LSKLYWYGQLSYLSQISKYYMNQDLENVNREIHGLRHFRDKYGKRR"
     gene            complement(18128..18739)
                     /locus_tag="VVR63_000694"
     CDS             complement(18128..18739)
                     /locus_tag="VVR63_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU6128735.1"
                     /translation="MEFFDKFHALCFGFLVLIIVITVPYTINHGGFFQNESALILVSL
                     LVTSLSVAYARKFEMISFGMLSKKQLLLFIAIFLLSVLETLVYIHFFAVSSGSGVQHL
                     AEVSRGISLSLILTTSVFGPIQEELIFRGLLQGAVFDNSWLGLVLTSSLFSFMHGPSN
                     VPSFIFYLLGGLLLGFAYKKSQNLWVSTLVHMFYNSWPLLYYL"
     gene            complement(18890..19123)
                     /locus_tag="VVR63_000695"
     CDS             complement(18890..19123)
                     /locus_tag="VVR63_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6128736.1"
                     /translation="MYKHLFFLDSKTLDRLTPYILVLASDTIAFNVFVLTFVSAVVFN
                     FLNSMLALMAIFIGAGYVVGFWLLILNENQRAN"
     gene            complement(19165..19854)
                     /locus_tag="VVR63_000696"
     CDS             complement(19165..19854)
                     /locus_tag="VVR63_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU6128737.1"
                     /translation="MKKYQLLFKISAVFSYLFFVFGLSQMTLIIQNYWQFSSQIGNFV
                     WIQNFLSLLFSGVMIWILVKTGHGYLFHIPRKKWLWYSILTVLVVVLQISFNVQTAKH
                     VQSTAEGWAVLIGYSGTNFAELGIYITLFFLTPLMEELIYRGLLQHAFFKHSRFGLDL
                     LLPSILFALPHFSSLPSLLDIFIFATSGIIFASLTRYTKSIYPSYAVHVINNIFATLP
                     FLLTFLHRVLG"
     gene            complement(19906..20289)
                     /locus_tag="VVR63_000697"
     CDS             complement(19906..20289)
                     /locus_tag="VVR63_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HEU6128738.1"
                     /translation="MKYRLFFVIFLSSVLDILLGTFLQISIVSIGWLVLYSGLFEAGV
                     FLLANKGVAVKIKEVDIRNRFKFIFGKTLWFQILLLIFLIIKLYLGLDARLILFYGHI
                     FIVFNALMYLLSSSQVSLKKNKLSS"
     gene            complement(20918..21289)
                     /locus_tag="VVR63_000698"
     CDS             complement(20918..21289)
                     /locus_tag="VVR63_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6128739.1"
                     /translation="MIKKNHILCEIVPGSVAFACFYLSISISSVFQFLLVVINLTSIL
                     VTVYLTREMRLREFEDDDLVSPRTNQLMFIGLTGFMSIICLYRGITAGESYQQLIAYI
                     GAILCLIIMLLLIWGLKYYKK"
     gene            complement(21757..21876)
                     /locus_tag="VVR63_000699"
     CDS             complement(21757..21876)
                     /locus_tag="VVR63_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000346296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HEU6128740.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDDLIRKIFSKSSKKDTDSTL"
     gene            complement(21980..22129)
                     /gene="blpO"
                     /locus_tag="VVR63_000700"
     CDS             complement(21980..22129)
                     /gene="blpO"
                     /locus_tag="VVR63_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpO"
                     /protein_id="HEU6128741.1"
                     /translation="MNTKMMSQFSVMDNEMLACVEGGDIDWGRKISCAAGVAYGAIDG
                     CATTV"
     gene            complement(22373..22621)
                     /gene="blpK"
                     /locus_tag="VVR63_000701"
     CDS             complement(22373..22621)
                     /gene="blpK"
                     /locus_tag="VVR63_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpK"
                     /protein_id="HEU6128742.1"
                     /translation="MDTKMMSQFSVMDTEMLACVEGGGCNWGDFAKAGVGGAAVVAAL
                     GCAAGGVKYGKILGPWGAAIGGIGGAVVCGYLAYTATS"
     gene            complement(22690..22959)
                     /gene="blpJ"
                     /locus_tag="VVR63_000702"
     CDS             complement(22690..22959)
                     /gene="blpJ"
                     /locus_tag="VVR63_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpJ"
                     /protein_id="HEU6128743.1"
                     /translation="MNTKMLSQLEVMDTEMLAKVEGGYSSTDCQNALITGVTTGIITG
                     GTGAGLATLGVAGLAGAFVGAHIGAIGGGLTCLGGMVGDKLGLSW"
     gene            complement(23426..23623)
                     /gene="blpI"
                     /locus_tag="VVR63_000703"
     CDS             complement(23426..23623)
                     /gene="blpI"
                     /locus_tag="VVR63_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpI"
                     /protein_id="HEU6128744.1"
                     /translation="MNTKMMEQFSVMDNEELEIVSGGRGNLGSAIGGCIGAVLLAAAT
                     GPITGGAATLICVGSGIMSSL"
     gene            23905..24492
                     /locus_tag="VVR63_000704"
     CDS             23905..24492
                     /locus_tag="VVR63_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C39"
                     /protein_id="HEU6128745.1"
                     /translation="MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKT
                     NKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDVPYPFIVHVNKEGKLQHYYVVYQ
                     TKKDYLIIGDPDPSVKITKMSKERFFYEWTGVAIFLATKPSYQPHKDKKNGLLSKLPS
                     SDFQTKISHCLHCSLKLIGHYYQYRWFLLSPRNLG"
     gene            24419..26062
                     /locus_tag="VVR63_000705"
     CDS             24419..26062
                     /locus_tag="VVR63_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HEU6128746.1"
                     /translation="MVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVI
                     TYILQQVMSFSRDYLLTVLSQRLSIDVILSYIRHIFELPMSFFATRRTGEIISRFTDA
                     NSIIDALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLISIPIYMFIIFSFMKPFE
                     KMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYS
                     ILQTSLKQGTKLVLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQT
                     KLQSAKVANNRLNEVYLVESEFQVQENPVHSHFLMGDIEFDDLSYKYGFGRDTLTDIN
                     LTIKQGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRHINY
                     LPQQAYIFNGSILENLTLGGNHMISQEDILRACELAEIRQDIERMPMGYQTQLSDGAG
                     LSGGQKQRIALARALLTKAPVLILDEATSGLDVLTEKKVIDNLMSLTDKTILFVAHRL
                     SIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK"
     gene            26073..27434
                     /locus_tag="VVR63_000706"
     CDS             26073..27434
                     /locus_tag="VVR63_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HEU6128747.1"
                     /translation="MNPNLFRSVEFYQRRYHNYATVFIIPLSLLFTFILIFSLVATKE
                     ITVTSQGEIAPTSVIASIQSTSDNPILANHLVANQVVEKGDLLIKYSETMEESQKTAL
                     ATQLQRLEKQKEGLGILKQSLEKATDLFSGEDEFGYHNTFMNFTKQSHDIELGITKTN
                     TEVSNQANLSNSSSSAIEQEITKVQQQIGEYQELRDAIINNRARLPTGNPHQSILNRY
                     LVASQGQTQGTAEEPFLSQINQSIAGLESSIASLKIQQAGIGSVATYDNSLATKIEVL
                     RTQFLQTASQQQLTVENQLTELKVQLDQATQRLENNTLTSPSKGIVHLNSEFEGKNRI
                     PTGTEIAQIFPVITDTREVLITYYVSSDYLPLLDKGQTVRLKLEKIGNHGTTIIGQLQ
                     TIDQTPTRTEQGNLFKLTALAKLSNEDSKLIQYGLQGRVTSVTTKKTYFDYFKDKILT
                     HSD"
     gene            27491..27619
                     /gene="blpC"
                     /locus_tag="VVR63_000707"
     CDS             27491..27619
                     /gene="blpC"
                     /locus_tag="VVR63_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system pheromone BlpC"
                     /protein_id="HEU6128748.1"
                     /translation="MDKKQNLTSFQELTTTELNQITGGGLWEDLLYNINRYAHYIT"
     gene            complement(27690..29030)
                     /locus_tag="VVR63_000708"
     CDS             complement(27690..29030)
                     /locus_tag="VVR63_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU6128749.1"
                     /translation="MNIAWILLYTLVTNGLEIVIFFKVDGIDLTFERIFKAFLFKILL
                     AFVFVMISYIVGNVYLSYFMEPLYGIGLSFLLLRGLPKKLLFFYGLFPMILVNLFYRG
                     VSYFVLPFLGQGQVYDGYSFTGLCIIIFNFFISLAFLKWLDYDFTSLRKEILDKAFQK
                     SLTQINWIMGGYYLVMESLSFFEYEQSIQSKTVRHLILVFYLLFFMGVIKKLDTYLKE
                     KLYERLEQEQALRYRDMERYSRHIEELYKEVRSFRHDYTNLLTSLRLGIEEEDMEQIK
                     EVYGSVLKDSSQKLQNNKYDLGRLVNIRDKALKSLLAGKFLKARDKNIVFNVEVPEEI
                     QVEGMSLLDFLTIVSILCDNAIEASVEASQPHVSIAFLKNGAQETFIIENSIKEEGID
                     ISEIFSFGASSKGEERGVGLYTVMKIVESHPNTSLNTTCQNQVFRQVLTVIHTE"
     gene            complement(29044..29781)
                     /locus_tag="VVR63_000709"
     CDS             complement(29044..29781)
                     /locus_tag="VVR63_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001219153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU6128750.1"
                     /translation="MRIFVLEDDFSQQTRIETTIEKLLKAHHIIPSSFEVFGKPDQLL
                     AEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIRDRDPYALIVFVTTHSEFMPLSFRYQ
                     VSALDYIDKALSAEEFESRIETALLYANSQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
                     LETSPRAHRVILYTKTDRLEFTASLEEVFKQEPRLLQCHRSFLINPANVVHLDKKEKL
                     LFFPNGGSCLIARYKVREVSEAINKLH"
     gene            complement(29786..30124)
                     /locus_tag="VVR63_000710"
     CDS             complement(29786..30124)
                     /locus_tag="VVR63_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU6128751.1"
                     /translation="MKYMIIQTQKTVYKVNIDDIYYIQTHPTKAHTVQIVTEEASFNM
                     LQNLSNLENQCGETLMRCHRNCLVNLDKLKSIDFQERILFLGEEGQYAVKYARRRYRE
                     IRQKWLKEGE"
     gene            30400..30729
                     /locus_tag="VVR63_000711"
     CDS             30400..30729
                     /locus_tag="VVR63_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HEU6128752.1"
                     /translation="MTDTDPIKRAHTLITDLNKAYQACKQASADDVRFQEQLNSILGF
                     LAKAETVDNRFLIELEKFYQTSSLLMGLSALDPDAPTRAAWRAYDRFHFDQVKTKLIL
                     NENQRAN"
     gene            complement(30897..31946)
                     /locus_tag="VVR63_000712"
     CDS             complement(30897..31946)
                     /locus_tag="VVR63_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6128753.1"
                     /translation="MKDLFLKRKQAFRKECLGYLRYVLNDHFVLFLLVLLGFLAYQYS
                     QLLQHFPENHWPILLFVGITSVLLLLWGGIATYMEAPDKLFLLVGEEEIKLHLKRQTG
                     ISLVFWLFVQTLFLLLFAPLFLAMGYGLPVFLLYVLLLGVGKYFHFRQKASKFFTETG
                     LDWDYVISQESKRKQVLLRFFALFTQVKGISNSVKRRAYLDFILKAVQKVSGKIWQNL
                     YLRSYLRNGDLFALSLRLLLLSVLAQVFIEQAWIATAVVVLFNYLLLFQLLALYHAFD
                     YQYLTQLFPLDKGQKEKGLQEVVRGLTSFVLLVELVVGLITFQEKLALLALLGAGLVL
                     LVLYLPYQVKRQMQD"
     gene            complement(31943..32674)
                     /locus_tag="VVR63_000713"
     CDS             complement(31943..32674)
                     /locus_tag="VVR63_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6128754.1"
                     /translation="MLEIKNLTGGYVHVPVLKDVSFTVESGQLVGLIGLNGAGKSTTI
                     NEIIGLLAPYSGSININGLTLQGDATSYRKQIGYIPETPSLYEELTLREHIETVAMAY
                     GIEQKVAFERVEPLLKMFRLEQKLDWFPVHFSKGMKQKVMIICAFVVDPSLFIVDEPF
                     LGLDPLAISDLIQLLEVEKQKGKSILMSTHVLDSAEKMCDAFVILHKGEVRAKGNLLQ
                     LREAFDMPEASLNDIYLALTKEEDL"
     gene            32742..33152
                     /locus_tag="VVR63_000714"
     CDS             32742..33152
                     /locus_tag="VVR63_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEU6128755.1"
                     /translation="MSDCIFCKIIAGEIPASKVYEDEQVLAFLDISQVTLGHTLVVPK
                     EHYRNLLEMDATSASQLFAQVPKVAQKVMKVTKAAGMNIISNCEEVAGQTVFHTHVHL
                     VPRYSADDDLKIDFIAHEPDFDKLAQVAETIKNA"
     gene            33162..33449
                     /locus_tag="VVR63_000715"
     CDS             33162..33449
                     /locus_tag="VVR63_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6128756.1"
                     /translation="MKLSNLLLFAGAAAGSYLVTKNRQTITDEVLNTTDRVQAIKDDV
                     DIIQNSLQIIDQQKELIKEYQEDLTYKFKVLEKDIQTRLAVIKEMQGTEDK"
     gene            33611..33895
                     /locus_tag="VVR63_000716"
     CDS             33611..33895
                     /locus_tag="VVR63_000716"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6128757.1"
                     /translation="MHHNLGNSYSIKIKKQTRKLGTDCSKHRFKVVDRTDEVSSKHCF
                     EVVDTTDEVSSKHCFEVVDRTDEVSNHTHDKPTLTWFEEIFEEYHSPFHN"
     gene            complement(34207..35343)
                     /gene="dnaJ"
                     /locus_tag="VVR63_000717"
     CDS             complement(34207..35343)
                     /gene="dnaJ"
                     /locus_tag="VVR63_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HEU6128758.1"
                     /translation="MNNTEFYDRLGVSKNASADEIKKAYRKLSKKYHPDINKEPGAED
                     KYKEVQEAYETLSDDQKRAAYDQYGAAGANGGFGGAGGFGGFNGAGGFGGFEDIFSSF
                     FGGGGSSRNPNAPRQGDDLQYRVNLTFEEAIFGTEKEVKYHREAGCRTCNGSGAKPGT
                     SPVTCGRCHGAGVINVDTQTPLGMMRRQVTCDVCHGRGKEIKYPCTTCHGTGHEKQAH
                     SVHVKIPAGVETGQQIRLAGQGEAGFNGGPYGDLYVVVSVEASDKFEREGTTIFYNLN
                     LNFVQAALGDTVDIPTVHGDVELVIPEGTQTGKKFRLRSKGAPSLRGGAVGDQYVTVN
                     VVTPTGLNDRQKVALKEFAAAGDLKVNPKKKGFFDHIKDAFDGE"
     gene            complement(35745..36101)
                     /locus_tag="VVR63_000718"
     CDS             complement(35745..36101)
                     /locus_tag="VVR63_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanine-N7)-methyltransferase"
                     /protein_id="HEU6128759.1"
                     /translation="MSVLDEEYLKNTRKVYNDFCNQADNYRTSKDFIDNIPIEYLARY
                     REIILAEHDSCIKNDEAVRNFVTSVLLSAFVSAMVPAMISLEIQTYKFVIPFIIGMIW
                     TVVVFLMINWNYIGKY"
     gene            complement(36103..37926)
                     /gene="dnaK"
                     /locus_tag="VVR63_000719"
     CDS             complement(36103..37926)
                     /gene="dnaK"
                     /locus_tag="VVR63_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HEU6128760.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNKLGGDDFDQKIIDHLVAEFKKEN
                     GIDLSTDKMAMQRLKDAAEKAKKDLSGVTSTQISLPFITAGEAGPLHLEMTLTRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQTIVIQSNSGLTDEEIDRMMKDAEANAEADKKRKEEVDLRNE
                     VDQAIFATEKTIKETEGKGFDAERDAAQAALDDLKKAQEDNNLDDMKTKLEALNEKAQ
                     GLAVKLYEQAAAAQQAQEGAEGAQATGNAGDDVVDGEFTEK"
     gene            complement(38406..38930)
                     /gene="grpE"
                     /locus_tag="VVR63_000720"
     CDS             complement(38406..38930)
                     /gene="grpE"
                     /locus_tag="VVR63_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HEU6128761.1"
                     /translation="MAQDIKNEEVEEVQEEEVVETAEETTPEKSELDLANERADEFEN
                     KYLRAHAEMQNIQRRANEERQNLQRYRSQDLAKAILPSLDNLERALAVEGLTDDVKKG
                     LGMVQESLIHALKEEGIEEIAADGEFDHNYHMAIQTLPADDEHPVDTIAQVFQKGYKL
                     HDRILRPAMVVVYN"
     gene            complement(38957..39991)
                     /gene="hrcA"
                     /locus_tag="VVR63_000721"
     CDS             complement(38957..39991)
                     /gene="hrcA"
                     /locus_tag="VVR63_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HEU6128762.1"
                     /translation="MVTERQQDILNLIIDIFTKTHEPVGSKALQESINSSSATIRNDM
                     AELEKQGLLEKAHTSSGRMPSVAGFQYYVKHSLDFDRLAENEVYEIVKAFDQEFFKLE
                     DILQEAANLLTDLSGCTVVALDVEPSRQRLTAFDIVVLGQHTALAVFTLDESRTVTSQ
                     FLIPRNFLQEDLLKLKSIIQERFLGHTVLDIHYKIRTEIPQIIQRYFTTTDNVIDLFE
                     HIFKEMFNENIVMAGKVNLLNFANLAAYQFFDQPQKVALEIREGLREDQMQNVRVADG
                     QESCLADLAVISSKFLIPYRGVGILAIIGPVNLDYQQLINQINVVNRVLTMKLTDFYR
                     YLSSNHYEVH"
     gene            complement(40155..40664)
                     /locus_tag="VVR63_000722"
     CDS             complement(40155..40664)
                     /locus_tag="VVR63_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001088691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HEU6128763.1"
                     /translation="MNSRVEFRIFTIVDLDKKEEYLHEMHLKGWRYRTSRFGLFYFEQ
                     GQPDDVIYRIYDSRFLKEHKRELQDFRDRGWELIGAGSCSILRKSSSDLLPEDQVYMS
                     KGLKWEVMRSRLRSCIATFLGGLVVCMSLFREDLSMSFFLIFVLYAFLISYLIHGYFR
                     LKRKYRVDE"
     gene            41272..43605
                     /locus_tag="VVR63_000723"
     CDS             41272..43605
                     /locus_tag="VVR63_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEU6128764.1"
                     /translation="MVEFIKSKKEMSEEDIKANFITPAIVSKGWKNGEHIAYEEYFTD
                     GRIEVRGDKARRKEGKKSDYSLYYQFGTRIAIVEAKDNKHSVRAGLQQAIEYGEILDV
                     PFVYSSNGDGFIEHDRITREERELELDEFPTREELFSRMTKEKGLTYEITEAISTPYY
                     TDAFSMKTPRYYQQIAINRTIETVARGQKRVMFVMATGTGKTFMAFQIIHRLRKAGLA
                     KRVLFLADRNILVDQTMAEDFKPFEKVMTKITPKLLTAPEKLNSFEIYLGLYQQLTGE
                     DGTETHYQKFDKDFFDLIVIDEAHRGSAKENSNWRKIIDYFSSATQIGMTATPKETKN
                     ASNTEYFGEPIYTYSLKQGIEDGFLAPYRVMRVNLDVDVDGYRPETGKVDTNGQLIED
                     RYYGRKDFDKTIVIDDRTQRVAKFVSDYMKQNNARFDKTIVFCVDIDHAERMRAALVK
                     ENLDLVQEDYRYVMQVTGDNAEGKAQLDNFMDVNSNFPAMVTTSKLLTTGVNAKTCRL
                     IVLDSNIQSMTEFKQIIGRGTRLYPQKGKEFFTIIDFRNVTNLFADPDFDGEPVKVLE
                     TGAKTVSGSTPGFVDEEGDPVEKYIVTDKQVTILNSTVQVLDENGKLITESLTDYTRK
                     NILGSYATLNDFITVWHTADKKKLILDELYKKGVYLDAIRESEGISEQEIDDFDLLLK
                     LAYGQKELTKTERINKLKQSGYLYKYSEEARAVLEILLNKYMDKGIGELESIETLKLP
                     EFQIYGGTFKIINTYFGDKKRYLQAIKELEQELFTVA"
     gene            43618..45081
                     /locus_tag="VVR63_000724"
     CDS             43618..45081
                     /locus_tag="VVR63_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEU6128765.1"
                     /translation="MSITSFVKRIQDITRNDAGVNGDAQRIEQMSWLLFLKIYDSREM
                     VWELEEDEYESIIPEELKWRNWAHAQNGERVLTGDELLDFVNNKLFKELKELEITSIM
                     PIRKTIVKSAFEDANNYMKNGVLLRQVINVIDEVDFNSPEDRHSFNDIYEKILKDIQN
                     AGNSGEFYTPRAATDFIAEVLNPKLGESMADLACGTGGFLTSTLNRLSSQRKTSEDTK
                     KYNTAVFGIEKKAFPHLLAVTNLFLHEIDDPKIVHGNTLEKNVREYTDDEKFDIIMMN
                     PPFGGSELETIKNNFPAELRSSETADLFMAVIMYRLKENGRVGVILPDGFLFGEGVKT
                     RLKQKLVDEFNLHTIIRLPHSVFAPYTGIHTNILFFDKTKKTEETWFYRLDMPDGYKN
                     FSKTKPMKSEHFNPVRDWWENREEILEGKFYKSKSFTPSELAELNYNLDQCGFPKEEE
                     EILNPFELIQNYQAERATLNHKIDNVLADILQLLEDK"
     gene            45081..>45755
                     /locus_tag="VVR63_000725"
     CDS             45081..>45755
                     /locus_tag="VVR63_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU6128766.1"
                     /translation="MTPEQLKASILQRAMEGKLVPQNPNDEPASELLKRIKAEKEKLI
                     SEGKIKRDKKETEIFRGDDGKHYGKFADGSTQEIDVPYDIPDTWEWVRIKSIYWNFGQ
                     NKPEKSFRYIDTSSIDRKKNIINYKNLQYLSPEQAPSRARKLVSQNSVLFSTVRPYLK
                     NIAVVRELKEYLIASTAFIVLDTLLNETYLKYYLLSDNFINRVNNKSTGTSYPAINDY
                     NFNLLLI"
BASE COUNT        14049 a         9730 c         8244 g        13732 t
ORIGIN      
        1 cggattttta tcgctctgaa catcaaaaaa gaaaggacga aatttgtcct ttctcgaact
       61 tagcttttct tcaacccact acaattgaca aagagccaaa ctttgatgat atacgttttc
      121 ttgtgagaat atttacttca ttttttccta aaattcaatg tttactcagt atttggatta
      181 tgaaaaatcg aggtctaaat ctagatacat tttttctgaa gacaaatcat tttgaccacc
      241 gagcaagaga ttttcaaaaa aagctgttaa aaactcagga cgtcgctgta aaatctttgc
      301 attatctaat accaaggcat cacgaaaata cttggaatgt tgctgaaatg gtatattatc
      361 aatatcaaaa ccaaactcac gaagatactg aatcaaaaag accgttactg tccgagtgtt
      421 tccttcgcga aatggatgaa tctgccagat tcctgaaata aaatgctgga tttgtttaac
      481 cacatccgcc tgagttagtg tcgcatatgc aacttgtttt tcctgattaa aatcataatc
      541 taaggtcatt tgaatcatgg agtaatcaga gtacacaaca ctttcaccat tcaaaacagg
      601 ttcattcttt gtgatattgg tctgacgaaa ttgccccacc ggaatagagg gttcaaatat
      661 atcttgaaac aactccttat gaatagcaag taaggtcgca ggactaaagc taaagcctct
      721 tcgagacaat agttctacaa tacgtagaga aaccaagtct gcctcttccg tacttgcatc
      781 aatagtatgg tgataagccg ttgcatcctc ataaacctgc tcataagtca gttctccccg
      841 ggactgtttc tcagccaaag attccatata cgctgatggc actagattgt caactttctg
      901 cagaccaaaa cctatccgcc ataaatcacg cttcgcttca taagacaagt ttggattgtc
      961 aatgttgtaa gttgattgca tagaaatatc ctttcaattg tttttcttca ttaccagtaa
     1021 atcacgaaat tggttggaaa ctggcttaaa ctataaaaag tcctcacaat aggttctatg
     1081 atatatatat atatacttca tgtaaataat aaaagagtta taatcagcac tactgataaa
     1141 ttcaataccg atttcgccat cttaaaactt agtcaaacga ataccgttga tttccagttc
     1201 attaagtcgt tgacctgtca agacttctcg ttccttcaac tggaaaagtt aagggggaac
     1261 taatacaaat cctctacgct tctatattca atgatttcat ttttgataat attcttttta
     1321 aactcaaaat gttttaaagg attatcgatt aacactaact ttggaatatc atctagattt
     1381 gtgaccaagg ataaaataaa atccgattga aactccttga ctttttcaaa ttcttttgca
     1441 gttaaacgca cacgcccctt agattttcgg atacctttta cttcggcaag gtaagaatac
     1501 tcttggacat ctacctgaaa gtcatatcca tcaccataaa gacgggcatc ggttaactgt
     1561 ccaccttgga atttttcttc tttatcaaaa tgaaggataa aataattctc agcctccatt
     1621 cccgtttcct gtagacgttt gaatttagtt cgaactattg gtttttcaac gatggttatg
     1681 cctgttttct tcccttcact ggcaagtaac attttaacta tttcagcata actatgaaca
     1741 tcttcatttc caaacatcat atcaattaaa tctttacgaa aacgataaac ttcagctttc
     1801 tgccaccaac cttttcgatt attgtcaaaa taaggatcaa ataagtccat tctatttttt
     1861 acaactccag ttgtttcagc aatttccaga gaaaccacat agcgataaaa ctccgacttg
     1921 ctagagcatt gaaattcttt tataaaaagc ttgtcaaact tggcaagacc gtagccaatt
     1981 aaatttaaca attcataatg agggtgtttg gacatcactt tctccatcaa tagatattga
     2041 tttcattata ccaaaaaaca cggctcatca ccgtgtttct gtgtttattt caccaacttc
     2101 ttcatctcat caatacgtgc tacggtcgca tcatacttag cttggtaatc tgcttgcttg
     2161 tcgcgttctt tttggacaac ttctggttta gcgttggcga cgaagcgttc gttgctgagt
     2221 tttttgccaa ccatgtcgag ttctttctgc catttggcaa gttctttttc cagacgtgcc
     2281 aattcttctt cgacattcaa gaggtctacc agtggcaaga agatttcggc tcctgtgatg
     2341 acgcttgaca tagccagttc aggtgcaggg atggttgatg cgatttccaa gtgttcagga
     2401 tttgtgaaac gtttgatgta gttgacattg ctgttaaaga aggcttccaa gtcgctatcg
     2461 cttgtcttaa caaggatagt gataggcttg cttggtgcta catttacttc cgcacgcgca
     2521 ttacgaacgg cacggatcaa gtctttgaga ctttccacac cagtgtgggc agcaaggtcc
     2581 tcaaagactg ggttgacagt tgggtatgct gctgtcacga tagagccttc agcgtactga
     2641 ccaaagattt cttctgtcac gaacggcatt attgagtgaa ggagacgaag gattttatcc
     2701 agcgtataga ggagaacaga tcgagtaatt accttatcgt cttcattgtc gctgtaaaga
     2761 acttccttgg tcaactcaac ataccagttg gcaaattctt cccaaatgaa gttgtaaagg
     2821 atatgaccag ccacaccaaa ctcgaactta tcaaagtttt cagtaacttt tgcaatggtt
     2881 tcgttgagat tgtggagaat ccagcggtcc gtcacattac cagcctcacc tgttgcaact
     2941 tttgtgacat tgtcatgcgc cacatccagc gtcaaacctc cattgttcat gaggatatag
     3001 cgagaaatgt tccaaatctt gttaataaag ttccatgaag catccatttt ctcataagag
     3061 aaacgcacgt cttgtcctgg cgcagaaccg tttgaaagga accatcgaag ggcatcggca
     3121 ccgtatttct cgataacatc cattgggtca atcccgttac cgagagactt agacatcttg
     3181 cgtccttgct cgtcacgaat aagaccgtgg ataaggacgt tttggaatgg ttgacggcct
     3241 gtgaattcca atgactggaa gatcatacga gacacccaga agaagatgat gtcgtaacct
     3301 gttaccaagg ttgaagttgg gaaataacgt ttaaagtctt ctgagtcgac ttcaggccag
     3361 cccatggttg aaaatggcca gagggcagaa ctgaaccaag tatccaagac gtcttcgtcc
     3421 tgagtccatc cgtcaccttc tggagcttct tcgccgacat acatttcacc atcagcattg
     3481 taccaggcag ggatttggtg accccaccaa agctgacgag agataaccca gtcgtggaca
     3541 ttttccatcc attgaaggaa ggtatcgttg aaacgaggtg ggtagaattc gaccttgtcc
     3601 tctgtgtctt ggttggcaat ggcgttctta gccaattggt ccatcttgac gaaccattga
     3661 gtagacaagc gtggctcaac tacgacacct gtacgttctg agtgaccaac actgtggaca
     3721 cgtttttcga ttttgacaag ggcaccgatt tcttccaact tagcaacgac tgccttacga
     3781 gcttcaaaac gatccatgcc tgaaaattca aaggcaagct cattcatagt tccgtcgtcg
     3841 ttcatgacgt tgacttgtgg caagttatga cgttggccaa ccaagaagtc atttggatcg
     3901 tgggcaggtg tgattttcac gacaccagta ccaaactcag gatctgcgtg ctcatctcca
     3961 acgattggga tgagtttatt agcgattgga aggatgacgt ttttaccaat caagtccttg
     4021 tagcgcgggt cttctggatt aaccgcaacc gcaacgtccc caaacatggt ctcaggacga
     4081 gttgtagcaa cttcaagggc gcgtgaacca tcttccagca tgtaattcat gtggtagaag
     4141 gcaccttcta catccttgtg aatcacctca atatcagaaa gggctgtgcg agctgctggg
     4201 tcccagttga tgataaactc accacggtag atccagcctt tcttgtaaag gtccacaaag
     4261 accttacgaa cagcttttga caaaccttcg tcaagagtga aacgctcacg agagtagtct
     4321 acagagagcc ccatcttgcc ccattgttcc ttgatagtag tggcatattc gtctttccat
     4381 tcccagactt tcgtcaagaa agactcacga ccaaggtcat agcgggaaat gccctcacca
     4441 cgcaagcgct cctctacctt agcctgagtg gcaatccctg cgtggtccat cccaggaagc
     4501 caaagggtat caaaaccttg catgcgtttt tgacggatga taatatcttg caaagttgta
     4561 tcccaagcgt gaccaaggtg aagtttacct gtaacgtttg gtggtggaat aacgattgaa
     4621 taaggcttag ccttttgatc gcctgaaggc ttgaaaacat cagcatcaag ccatttttgg
     4681 taacgaccag cctcaacctc ggctggattg tatttagatg aaagttcttt agacatgtgt
     4741 gtgtcctttc tctattttgt ttattttatt ttgaatttgc ttagcagctt cttctgcaga
     4801 caaattcgta ttatttattt taaagtagtg gtgcaactca ttcggttgat attgggaatt
     4861 taattgaagt gtttcagcgg tctctataat ttctctttca gatacctcaa tatgtcgttt
     4921 taagggtttg tactttaatc gattctccgt tcgatttcga cgtatgcact cttcaagact
     4981 tgtttccaac tcaacaaaaa gaatctcttg atgataatca tccaacaaac tctgaatttg
     5041 ctttaaatat atcagatgat actgatttga aaaatcaatt acatctgtta aaattactga
     5101 tcgctgattt cttgcactcg ctccaaggaa tgaaaaagtg attccacgaa caaattccca
     5161 catttcctct gtatagtcct gatagatttc tagtgcaaaa tcgatggctt gatggttata
     5221 aaatagggta gcatccgtca gtcgagataa ttcttgacca atggtcattt ttcctgatgc
     5281 tggagcacca atgatgaaaa gatgcatcaa atcacctccc attcactctt cagcaaggca
     5341 tatcttaaat catcacagca gttgccttga gcatctttgc ggtctcttat gcgagcttcg
     5401 agggtaaagc caagcttttc cgcgactcgt tgactttgaa ggttatatcc aaagcaagtt
     5461 agttcaatct tgtgaagacc caaatcttta aaggctaagt caatcaaggc acgcgcagct
     5521 tctggcacat aacctcgccc ccaatagtct gagtgtaagg tatagccgat ttccatcaca
     5581 tcatcttcat ggcgatggtt gaaatagata gagccaacga tcttatccgt tcctttgacg
     5641 acaatcccgt agcctgctgg gagattttcc ttttgattac gctccggaag aatgtgctcc
     5701 agataataaa tctcatcttc caaggtcttg actggaggaa aacctgctgg ataggcgacc
     5761 tctggcaaac tagcatagtc aaagatatcc tcagcatccg ccacagtacg gactcgtaaa
     5821 acgagacgtt ctgtttcgat tttatctggc agctcagttc ttgccatcct tcttcctcgc
     5881 ttttttgatg aaactgccct tcatatctac acgcttgtcc agatagcgat aaacgcgctg
     5941 atatccatct cccatgaaat aggttggggc aaacagttga tttttaaaat gtcccttttc
     6001 atccaggagt tctggggcaa caagtcgctc aagaatcttg gcaaagatgt ggcaaatacc
     6061 gtcttcctca acaatcctat ctacccgaca atctaaaaca agtggacagg cgtctaaaat
     6121 aggaatctga gttcgttcag aaatttcata atgcactccc aaacgttcca atttctcctg
     6181 atgactgata aaaccagcct gctccatcgc aagcatagaa gtttcatcag aaatattcac
     6241 agtaaatttt tgatactgtt tgatctgctc tgcggcattc tctctcgcaa cgactccaat
     6301 cacaacccaa tctcctagac tataagagga actacaggtc gtgatgttat agccaaaatt
     6361 ctaatcttga tatcctaaaa taaaaacagg aaaaccataa tatagtttac ttgtgttaaa
     6421 agattgcttc ataacaacct cctttgacta agacacaaaa gaaaagccct gccatctaca
     6481 tgacagggac gaatgtgttt atccgcggta ccacccaatt tcgggccaag cccgcatctt
     6541 tagtctttaa aataaaaaga cagaaatatt tcattttttc agtcattagc aaccagtttt
     6601 gacacatttg tggacttctc agcgccgcca ctttctgtaa aatgtgggat tcaaaacacc
     6661 tctaatggct ctattgtagc aagatttttt cggaaatgca aggctcaaga aaaattactt
     6721 gaacttgatg ccattttctt tcaatttctt gatggtagct ggaccgattc ctttcaagtc
     6781 aaggagttct ttttcagtcc agtttttgaa atctgaagca gacttgattc cttcatcata
     6841 gaaagtcttg gcacgatcaa gtggaagtcc acccaagttt gctgcaaaat cttctacaga
     6901 attagctact ttttgagctt gctctttggt agcttctact gcttgttcaa cttttttaga
     6961 aacagcctta ccagctgcgc ttgctgactg ttctgcacgc ttcacgactt tttttgtctc
     7021 atctacaacc ttagtcaccg tacttgaaaa ggcacctgcg cgacggaggc catttcgtaa
     7081 ttgtttttta cgattgagtt tctttgacat gataaaatcc tttcaataaa aaatccctgc
     7141 tctgacaagg atttaacata aacattctat caagatttta gtgaaaaatc aagaatcttt
     7201 ctcgtttaat aatttcgctc accaaacaag ccttctggca aatcatggaa tcccttgcct
     7261 gctttgaagt tttcaaactt accaagcaag aactgataag catccaagcg actctcgtag
     7321 cgaatcatgg catctttggc acgctcgtcc tggtcttctt cgtaaacttt ttgactttcc
     7381 ttgtgcgcca tatcgttaat catgatttgg gtattgaccc aagcttcaaa ttccttcata
     7441 aattcttgtt cgtaactcat tttttctcct tattctaatc cacgaaaata gtccgtatca
     7501 atctcacggt agggctggat atcctgaaca tactccaaca ctccttggaa ttctccgtct
     7561 tcatcgtgta ctgcagcata ggtgatgtgg acaaacttac ctcgcgactc agacttgaac
     7621 cacatttcat acttgtcttt gcttccctca cgaagcccct tcatgatagt tttgaccttg
     7681 tccaagtact taggcggatg gcagagttcg acattgcgcc cgacttggga cggcgtccgt
     7741 ttgaaaatca tctcatcagc tggcgtattg tcattgtaat actggaaaat atcttcttta
     7801 ttgacaaagg taatctccat agggagatga ttgaggatga gattggcctg ctcgactgaa
     7861 agatagccat taccaaaagc ctgttgacta tggcggtcca gcacagcttc cttttcctta
     7921 ggggtaaagg taatggtaaa atggccttct ggcgtatcta tgacttgttg aacttgacct
     7981 tctgccgtat ctagctgtac aggctcctct gcaatctttt cctcaataaa gctctgtcgt
     8041 tctggcaccc atttctctga cggacggatg atggcatagc cataggcatc gctctcctcc
     8101 gcaatctgaa gccagtcatc ctgagtaaaa gactcaagga gaatcatgag gaggatggac
     8161 tcttccttga aaatcatact ttcaaactct gtcgcaaaag cttcaaaagc ttcctttaca
     8221 ctgctaattg acacttctgg tagtgacttg gctgtcgtta gagctgtttg aaagagttcc
     8281 ctaatctgat catccactcc ccacataact ttgggaggtg aatcgtgtcc atagcgctcc
     8341 atgataggaa agaagagttc ttccttacgt tggtaatgga tgtcaaattg acccacaagt
     8401 cccatctgac gcaccaaacc cttacgcatc tccgccagca tttcctcgtc ttccatagac
     8461 tcataggtat ctaacaatct acgaatgcga atcaaggccg cacggagagc cagattttct
     8521 tctttgaaga cacgaactgg gtgacctgga tgctcagtat ctgaaacttc gacacctttg
     8581 atagcatttt taaaaagatt ggcatggaca tcacagagtt ccataacatc ttcaaaagtg
     8641 acgcccgaat ccgagttcat cagctcgtgc tccataaggg aaatctcgat ggctgacacg
     8701 cccgtaaagg tcgcatcaaa gcgatcttga accgactcag gagaggcgcc attgtgcaat
     8761 tctaacaaaa tatcccgtag gatatgaatc cgttcatctg tcattagtct aatccaatca
     8821 cttcgtagcc attcgcttcc agtgtgcgta caatcttgtc cataggagtt cctgctagct
     8881 tagaaccctg tttaagtgat actttacgac caactgtatt gcgcattaag ggattggcaa
     8941 ggggtttaaa acccaactcc actagaattt ccaagacttc tggatgcttg tccaccactt
     9001 ctgcaacagg aattgacaca tcgatgatat tgtccatgac gacctccatt gtatgttcta
     9061 atactcaatg aaaatcaaag agcaaactag gaagctagcc gcaggttgct caaaacagtg
     9121 ttttgaggtt gtagatagaa ctgacgaagt cagctcaaaa caccgttttg aggttgtgga
     9181 tagaactgac gaagtcagta acatatatac tgcaaggtga agctgacgtg gtttgaagag
     9241 attttcgaag agtataaaat gattttactg cttatattat accatatgga aagagaataa
     9301 aaaactagca gtggagttcc tgctagttct ctgcaacttg gattaccatc tagataagtt
     9361 taaagagcca atccaatatc ttaaacacta tcttgtaaaa cagcaattgg actgcaaaag
     9421 agatgatcat ccaaaagaat ttcacaatcc caataatcgg tttgataaaa agaatagcaa
     9481 gaagaccaaa aaaatttcat tctctctcct ctggcttaat gagccaccga gccgtatcca
     9541 ttaacttgtc ggcaataaaa agtttcccca gaccaacaac gacatggtca gctttcttta
     9601 tcgttttcat cacttttaca ccttgcacgg tcaaaaagta attaccataa attttagcaa
     9661 aagctttgat aggattcata ttactctcct ttgatgattt cagcctcttt tcggattgtt
     9721 tcaacatctt cttgatattg aacttcacta tagttgacta gcttggataa ttctttctgc
     9781 aagctttccc ccattggttt catagttgca aaggttaaac cacctgaaat gataccaccc
     9841 aagataggaa taaatttccc tattcctttg gccagccctc ccttggtaag attcacacca
     9901 aatattctta agactttttt caaaataggg taccaaagcg tctttgttaa agctttatta
     9961 ggcactgttt tcattacctg tttggcaatt gttataccac cagcacgtag caaagcagcg
    10021 gttccattca cccctaacat tacgcctaga taaagcaaga gggtattttg agcatcttca
    10081 ctcaactcct cgcgtgaagc ccaaagatcc tcataaccat aaatataacc taattcttga
    10141 gccaatttca gagagaaagc ataaaattga gccacatcag ctggaatggt aattgccata
    10201 gcaagccatc cagctaatcc tgccaaaaca gaagtcccac tcgctaataa tacattgtcc
    10261 cgaatacaag cattagctac acgatctaat atttcttgag atagaagagt cgttgtacct
    10321 tgttccaata aggtaggaat atcttttgga tccaattctt tggaaaactt atccactaaa
    10381 aatttcgaac gatcaacctt aacaacaggt agtttcacca cttgttgcaa tacttgcata
    10441 gctaagtctt gttcagccat atacaaactc cttatttctt ttttacacct tatcatatta
    10501 tatttcctac aaaaaaagca ttttctaatt agataacatt aaaaaataca gaatcccttt
    10561 tttatattaa aacgaaacaa gaacaggaca aatcgatcag gacagtcaaa tcgatttcta
    10621 acaatatttt agaagtagag gcgtactatt ctagtttcaa tctattataa aagaatattt
    10681 ttccatttca aattcaacct attttcctcc accaaaaaag aggggcaacc cctcttcttt
    10741 agttcttatc cagattgcgt agcatctcgt caatcttgtt tccatactcg atggactcgt
    10801 ctttgacgaa ggtcaaatct gggattttgt acaatttcaa attgcgacca agttcacgtt
    10861 tgatggtacc agttgctttt tcaagcccga tttggacttt ttggttatcc gaagcaaggt
    10921 tactcaaaat ggtgtaataa accttggcaa cagacaagtc acccagcatc tgaacatctg
    10981 tgatggtcac accttggaca cgtggatcac ggactttctt ttgcaaaatc tcattgactt
    11041 cacgcttgat ttccatgccc acacgatctg tacggaaatg atttgccatg atattccttt
    11101 ctctactttg aaccaaaagc taggccagca gacctagcta ttttaaactt cttgattttc
    11161 agtttaaatt gaaacgaagt tcaatttgaa gtcatctgct tctttcgccg tggtgaaagt
    11221 gatggaactg atttatcagt cccatcacag gggatttttg agaccctagg ctcaaaaata
    11281 agcaatgaaa ccatcggttt gcttgcgtcc ctcaccacct aagaaaggag caaaaaatct
    11341 tatctcttga tttcttccat gacatacgcc tcaatcacat catccatctt aatatcattg
    11401 tagccgtcga tcatcaatcc accttcacgg ccgtttgtaa cttccttaac gtcgtcttta
    11461 tagtgtttca agcttgcgag ttcaccatca tagataacga caccatcacg gataacacgg
    11521 actttagagt cacgggcaac cttaccgttg ataaccataa atccaccgat agttcccact
    11581 ttagacacct tgaaggtttc acggataacc gcttcaccaa taactttttc ttcaaattct
    11641 ggatcaagca tccctttcat agcttcttcc atctcttcga taaccttgta gataatgctg
    11701 tgaagacgga tttccacatc gtcagcttct gcttgttgac gagcttgtgg tgtagggcgt
    11761 acgttgaaac caacgataaa ggcatttgaa gcttcggcaa gggtcacgtc tgattcgttg
    11821 atagcaccga ccgctgagtg gacgatagtc actttgacac cttccacgtc aatcttttga
    11881 agtgaggcag aaagggcttc aacagaacct tgtacatcag ccttgatgat aacattaaca
    11941 gatttgagtt ccccagcttt aagggtatca aagaggtttt caaggctaac acgttgggta
    12001 gcttgacgtt gtttcatgag ggcacgtttg gcacgctctt cacctgctgc acgcgcagat
    12061 ttttcatcct cgtaaacggc aaagtggtca cccgccatcg gtgcttcgtt caaacctgtg
    12121 atagagactg gtgttgatgg tccagcaact ttaacacgac gaccaaggtc gttggtcata
    12181 gcacggacac gaccgaaggt atttccgaca acgattgggt cttgaacatt caaggtacct
    12241 tgttgtacaa gaagggttgc gaccgcacct tttcctttat ccaagcgcgc ttcgataacc
    12301 gtaccgattg cacgcactgt tgggtctgcc ttaagttctt ggatttcagc tacaagaagg
    12361 actgtttcca acaattcttc gatattttgg ttgaatttag ctgagatttc aacaaattca
    12421 gaatctccac cccaagcggt tgacatcaca ccatgctctg ccaattcacc gataacgcgt
    12481 tctgggttag cacctggttt atcaatcttg ttaatggcta cgatgattgg aacgttggcc
    12541 gcttttgagt ggttaatggc ttcgatagtc tgaggcataa ccccgtcatc tgccgctacg
    12601 accaagatcg taatatcggt aacagaagca ccacgcgcac gcattgatgt aaaggccgcg
    12661 tgtcctggtg tatcaaggaa ggtaatcttc ttaccatttt ccacgatttg gtaggcaccg
    12721 atatgctgag taataccacc tgcttcacct gtcgcaacac gtgagttacg aagagtatcc
    12781 aaaagggttg ttttaccgtg gtcaacgtgt cccatgatag taacaactgg tggacgctca
    12841 accaattcat cttcattgag ataaccatct tcgacaaaga aacgttcgat gtcagcatta
    12901 tccacttcaa ccttttgttt ggcttcgata ccgtaatcca ccatgaggag ttcaattgtt
    12961 tccccatcca aggattggtt ttgtgtggcc atgacaccca tcatgaaaag tttcttaaca
    13021 atttcagctg gttcacgttt gatacgtttt gcgatttccg caacggtcat accatctgta
    13081 tattcaaatt ctgttggcaa ttcatggaat ttacgctccg taacaggttt tggagtctga
    13141 ttacggttgt tcttgttatt gccttttttg ttctttttgt tgttattcca gttactattc
    13201 ttttgatttc tcacttgatt ttgactactt cgattctttt gttgttttct aggaccatct
    13261 tcttcatgat cataatcgtc acgatttttg tctggtcgag cttgtttttt acgacgtgta
    13321 tccactgcag gttctttttt ctcagggacg acttcaacca ctgcttgaac ttgctgtgct
    13381 tgttcagcta acttagccgc ttcttcaaag atttcctctg gttccttgcg tttgttagct
    13441 tgagccaagg cttctttagc agcctgatac tgcttgaagc gttcctcact tgaacgagcg
    13501 tactctgcat tttgctctgc ttttagggct gctgcacggg ctttaaagtc aatacgtgga
    13561 gccgcttgat ttgaacgttt atcctcttgc tgacggcgct catttctacg tttttgctga
    13621 ccttgctgct tcttagcttg gtcattaaag cgacgattgt cgcggttgct ttgaccttgt
    13681 tttccaccat tacggccgtc gtttttctga cggtttccgt tttgttgttg gtcacggtta
    13741 ttgcccttat tttgcttgcg tcgttctgcc tgctctttag cacgggcttc acgctcagcc
    13801 ttgaaattac gactttgcgg tttcactgct actttttctg ttttcggagc aactggctca
    13861 gccggttttg cctcttcctt agctacagct ggtttagctg gctcagattt ttcggctttc
    13921 ttttctgcac ttacttttgg tgctgcaggt tttgcttcta ctttcggagc agctgcaggc
    13981 ttaaagctgg cagcaatttt tgtagcgaca gcttcttcca cacttgatga gtggcttttc
    14041 acatccaagc ccaactcttt tgcacgcgct acaacttctt tactttcttt tccaagttct
    14101 tttgcgattt cgtacaatct tttcttagac aaatcatgtc ctcctcttct attccataag
    14161 agacctcatt ttctttgtaa atccagcatc tgttacagcc aaaacctttc tcgatttccc
    14221 gactgctatg cttaattcca gtgttgaaaa cacggttaca atttctactt gataataatg
    14281 acttttatct tgaatcttct tggtcagatt gggtccagca tcatgagcta gaaagaccaa
    14341 cttggccttg ccgtcttgaa tggccttgac caccaattct tcacccaata tgatgcgccc
    14401 tgctcgctga gcaagcccca agagattact tatcttttgc ttattcaagt cccaactctc
    14461 ttcttttcac tttgtgatcc acataagcga tcaactcgtc ataaaagctt tcttccactt
    14521 ccatgctaaa gctgcggtta aagaccttct tctttttcgc ctctagggct tctgcattgt
    14581 ctagtttgat ataagcgccg cggccattgg ccttgcccgt aggatcaata aagacttgtc
    14641 cttccttgtt cttgacaatg cggagcaaat cacgcttatc aatcacttcg ttagacacaa
    14701 cagacttgcg caaagggatt tttcttgttt tcatctttcc ctcctctagc agcttttatt
    14761 cttctacagt atcgttttct acttccaact ctactgaagc agcgtcttcc atggcttcaa
    14821 attcgctagc agacttgata tcgatacggt aaccagtcaa gtgagccgcc aagcgcacgt
    14881 tttgtccacg acgaccaatg gcaagagaaa gcttgttatc tggaacaacc accaaggcac
    14941 gtttgctgtc gttttcatca aagataactt ggtcaacctc agcaggagcg atggcattgt
    15001 agataaattc agctggatct gctacccact cgataacatc gatattttct tcgattggta
    15061 ccatgcgatc atttttagca tcgtaacgag ctgggtggaa tttgctagta atcttcttga
    15121 tattagcacc accacgtcca acgattgtac cgatagcatc cacgtttgga ttgtggctac
    15181 gaacagcaac cttcgtacgg tcacctgctt cacgagccac gctcatgatt tcaacagttc
    15241 catcataaac ttctggaatt tcttgctcca tcaaacgttt gatcatttct ggatggctac
    15301 ggctaacaaa gacgttcaca ccacgagggt tgtcttcaac cttgtaaaca taaacttcga
    15361 tacgatcatg agaagcaaaa acttctccag gaatttggtc ttgttttgac aattgggctt
    15421 cgatgctacc aaggttgaca tagataaagc ggttgtcaaa gcgttctact gtaccagaca
    15481 tgatttcttg ctcatgttct ttgtaagtat tgtaagtgat ggcacgtgtt tgcttgcgca
    15541 ttttttccat gatggtttgt ttggcagatt gggctgctac acgaccaaac tcagctggtg
    15601 cttcttcaaa cttgattttg tctccaagtt cataagctga attaatggca agagcatctt
    15661 tcaagctgat ttccaaacgg ctatcaaata cttcatcaac aacttcacgg acagtataaa
    15721 ctgtaaagtc acctgttttt tcgttgaagt caatagctac gctgtctgac tgaccatagc
    15781 gtctgcgata agcggaacga agcgactcta ctactgcgtc gatgatgtct tcttttttga
    15841 ttcccttgtc ttcttccaaa atgcggaagg cctctagcat ttctttactc atgttttctt
    15901 cacttttgaa tcctcaaaag ctatcctttc tttttctata atttaactgc taaacgtgct
    15961 tttgatacta aactatatgg aatttggaca gttttcttac gtgtcttgtc catatattcc
    16021 atagtcaact cgtcctcttc gaaggccaac aaggttcctt caaagacctt ttgcttatcg
    16081 atggcttggt agagcccgac atggatgtat ttcccaaccg ctccagcgac ggcatccttg
    16141 gttttcaaag gacgttccaa gcctggactg gtaatttcta ggaaatattg ttctgggaag
    16201 ggatctggct tgatggtgtc taggacagga ctgatcattt ctgtcaagtc tgccgtgtcg
    16261 ttcaaggtaa ttccttcagg tttatctaca aaaatactga gaatcatgtc actgccaatc
    16321 tttccatact cgatatccac gagttcaaaa ggagcttcta tgacaggttc tacaacttct
    16381 ctgactaatt ctacgattgt tgcgattgcg tccacctcct cataagcaag aggcgaagat
    16441 atttccccgc ctcacttttc atattcttac tatcagtata gcacgtttgc caacttatgt
    16501 aaagcaaaag cacttgtaca gcctaatttt aggctatctc ttaaaattct gcctcaactc
    16561 ggtagataac ttgccccttg tttgagaatt tttgctcgta ttctgtcatg acattgcctt
    16621 caaaatcact ggcatgcaaa tctaaccaga caccattgag tttcatgcca tattgagaaa
    16681 agctcactaa actgtactca aacaagccac ggttatccgt cttgaaatga atttctccat
    16741 tttcaggcaa gatacgtttg aaggtatcca agaaggtctt gtaggtcaaa cgacgctttt
    16801 catggcgttt tttcggccat ggatctgaaa agttcagata caagcgatca atctcaccgt
    16861 cttcaaaata gtcagttaag tcagaaccat ctacccacaa gagcttgatg ttaggcactc
    16921 caacttcaag caccttgtcc aaagcgtagc tcaaaacaga cttttgaata tcaatcccga
    16981 tatagttgat gtcagggttt tgcttggcca tacctgaaac aaaggcaccc tttccacttc
    17041 caacttccac atgaatggga ttatcattgc caaacaagtc ccgccatttt gccttggctt
    17101 ccaagggatt gaggaccaca tactggggat ttgcctctag taattctgtt gcccctttac
    17161 gatttctaac tctcatcttc tctttccata cttgtctcgg aaatgacgca aaccatgaat
    17221 ctcccgattg acattttcta aatcttggtt catataatac ttggaaatct gactcaaata
    17281 agacaattga ccataccaat acaatttact taataccgtt tgattgtact tgtaaccgta
    17341 gtaggtcaac cattccttcc actgatgttc tgaaatataa tggcagagca tatgggccac
    17401 atcaaacatg cgatcggtca agcgaaccga atcccaatct actaaataaa tcaagccact
    17461 atctgtctca atccaattac tatgtcgtac atctccatgg acaatggtcg catggtcctc
    17521 tctaaatcct ggaatagtct gacgtaaatc agccatcact tcactgataa aatgattttt
    17581 acgcaaagca tctggagccg tttcctgcca agactgtagt aaatctacag gtgtttccat
    17641 ggcatagccc aaacgactca attgtgtcat caacggacgt gagcgatgaa gacgggttaa
    17701 aatattgacg atttgcttac gattcatatc atagggggtc aatatcttgc ctgtcaacca
    17761 ttcttgagca cacatatcac gcccatctgc caaacgacga ctccataata attgtggagc
    17821 aatttgttct ctagctagac caggtaggat tggagaggtg ttcattttta caaagatgcg
    17881 cttcccgtca ggatagctac ccatataagc cttgccactt ttcccaggta tgggagtcag
    17941 tgttagctca ttatcaccca aatccatttc tttcctccgt ataaagtttc cttactattc
    18001 tactagtttt tggcctattc gtcaaccact ctaacccgat tctcaaagaa aagcctctgg
    18061 attggcttgg gtatcattat agcttgaaaa aggtaagcac catcttctgc ttaccttttc
    18121 ataattttta taaataatat aggagtggcc aactgttgta aaacatgtgg actagagtag
    18181 aaacccatag gttttgactc tttttataag caaagcccag caacaaaccc ccaagtagat
    18241 aaaaaataaa cgaagggaca ttagaaggtc catgcatgaa agaaaagaga gaggaagtta
    18301 gcacaagccc taaccaagaa ttgtcaaaaa ccgcaccttg aagaagtcct ctgaaaatga
    18361 gttcctcctg gatggggcca aaaactgagg tagtcaaaat caaagacagg gaaattcctc
    18421 tgctgacttc cgccaagtgt tggacccctg agccagaaga aacagcgaag aaatgaatat
    18481 aaaccagcgt ctcaagtaca cttagaagaa agattgcaat gaaaagcaaa agttgtttct
    18541 tgcttaacat cccaaaagaa atcatttcaa actttctagc ataagcaaca ctcagcgagg
    18601 ttacaagaag acttacaaga atcaatgcag attcattttg aaaaaaaccc ccatggttaa
    18661 tcgtataagg aactgtaatg acaattatta gtactaaaaa tccaaaacac aaggcatgaa
    18721 atttatcaaa aaactccata aaactatcct cctcaccaaa cagacttcct acgcgtcatt
    18781 ctttagttct agcctttcca aaacaaacca ttttatactc ttcgaaaatc aaattcaaac
    18841 cacgtcaacg tcgccttgcc gtactcaagt acagcctgcg gctagtttcc tagtttgctc
    18901 tttgattttc attgagtatt agtaaccaaa atccgaccac atagccagcc cctatgaata
    18961 tagccattaa agctagcatg gaatttagga aattaaaaac caccgcagat acaaaggtta
    19021 gcacaaaaac attaaaagca atggtgtcag aagccaagac tagaatatag ggtgtcaacc
    19081 gatctaaagt tttggaatct aggaaaaata agtgtttata catgataatc tcctctatgg
    19141 ctgaaaagca agccttttgt ttttttaccc caagacccta tgtaaaaaag tcagcaaaaa
    19201 tggtaatgtt gcgaaaatat tattgatcac atgcaccgca taggaaggat aaatgctctt
    19261 ggtatagcgg gtcaaactag caaagatgat gccagatgtt gcaaagatga agatatctaa
    19321 caaactaggc aggcttgaaa aatgaggaag agcaaataaa attgacggaa gaagcaaatc
    19381 aaggccaaat ctcgaatgct taaaaaaggc gtgttgcagt aatcctctat agattagctc
    19441 ttccataagt ggagtcagaa agaacaaagt tatatagata cctagctcag caaagttggt
    19501 cccactataa ccgatcaata cagcccaacc ttcagcagtt gactgaacat gtttagctgt
    19561 ctgaacgtta aaagagatct ggagcactac cactaatact gtcaaaatcg aataccaaag
    19621 ccattttttt cttggaatgt gaaagagata accatgacct gtcttaacca gaatccaaat
    19681 catgactccg ctaaatagca aactcaagaa attttgaatc cagacgaaat tgccaatctg
    19741 ggaagaaaat tgccaataat tttgaataat aagcgtcatc tgagaaagac caaatacgaa
    19801 aaataagtaa gagaaaactg cacttatttt gaatagaagt tgatactttt tcatagaaat
    19861 cctccctact atgacctcac cttgtcaggc tctactgctg taagattaag aagacagttt
    19921 gtttttttta aggctaacct gactactaga taatagatac attaaggcat taaagacaat
    19981 gaaaatatgt ccatagaata aaatcaacct cgcatccaaa ccaagataaa gtttgattat
    20041 caaaaagatg agcaaaagaa tttgaaacca taaggttttt ccaaaaataa atttaaagcg
    20101 atttcgaata tctacttcct tgatttttac cgccacccct ttattagcaa gaaggaaaac
    20161 tcctgcttca aacaaaccac tgtaaagaac aagccaccca atagatacga tagagatttg
    20221 taaaaatgtc cctaaaagaa tatccaacac actactcaag aaaataacaa aaaataatct
    20281 gtatttcata ttaaatacct ccattcattt atttcactaa caatttaata gagccttcta
    20341 ctcaaatatc ctgtcagaaa aggatagaaa gctacttttt ataatacttc aagccccaca
    20401 tgagcagaag cgtgataaac aagcagagaa tacacctata taagcgatta gttgttgata
    20461 gaattctgtt tctgaaatac ctctatacaa acaaatgaca aacataaaat ctgccaagcc
    20521 gataaacata agttgattgg ttctaggact aaccaaatca tcatttactt atatttaaga
    20581 gtatctcttt tatgttaatg tatgttagca ctgaaaagca agacaggcca ataatattta
    20641 aaatgaacag taacggggtt aagtctctaa aaaaattatc tactgacact acaagaaata
    20701 ctatacatat tatagtcgaa actatctttt tcttatccat aattatttac tcctttccta
    20761 acaaatccaa cttatcaatc aagagcgatt tttaacataa tgtagcagca cccgttgcaa
    20821 ctttgacaag tttagtatat cattgttttt taaaattttt catccaaatc ttgaattgtc
    20881 atcgaaacct cctaaattgc aaaaacttca ttagccccta ctttttataa tacttcaaac
    20941 cccaaatgag tagaagcatg atgatcaagc aaagaatagc accaatataa gcgattagtt
    21001 gttgataaga ttctcctgct gtgatacctc tatacaaaca aataatagac ataaagcctg
    21061 tcaagccgat aaacatgagt tgattggttc taggactaac caaatcatca tcttcaaact
    21121 ctcttaatct catttcccta gtaagataaa cagtaaccaa aatagaagtc aagttaataa
    21181 ctactaaaag aaattggaaa actgacgaaa tagaaataga taagtagaaa caagcaaagg
    21241 caactgaccc aggaacaatc tcacaaagaa tatgattctt tttaatcaag aaaatctttc
    21301 atttcttttc tttcttttta attaaagaaa aatagatcat aaccgcaatc atataggcta
    21361 tggtataaaa tagattatac caaatactct ccctaagcgg ataaagaaag atggacatga
    21421 tcagatacag aacgaaaata atcagtattt ttttcttcat aagttttcct cctaaatgtg
    21481 cgatttatct tagttgagca agaacattta cactgctagt atagcactta ttttgacctt
    21541 ggatcactca aatcataaat ggtcatcaaa acctcttgaa ttgtaaaaat taaaaaagca
    21601 agcatgaaaa acatactttc ctctttatat tgtattgata ccaacttgtt tgtagacttt
    21661 tcatcctgct atcacatatc attttgacag gcgaaacaat attaaagaaa ctcccctgta
    21721 aattaagcta gcaaatacag gggagaaatt tattttttag agagtactat ccgtatcctt
    21781 tttggaagat tttgaaaata tttttctaat taagtcatcc atataaggac caaatatacc
    21841 aactactaaa ccaataataa aacttttaaa atccataatt accaccaaca tgttgctgca
    21901 taggctacac ctccaagtat agctccacct gcagcaccag ttacacctat tcctatagca
    21961 aatggtccca atagaaatgt caaaccgttg ttgcacaccc atcaattgcg ccatatgcaa
    22021 cccctgctgc acaactaatt tttcttcccc aatcaatatc tccaccttca acgcaagcaa
    22081 gcatttcatt atccataaca gaaaattgtg acatcatttt tgtattcata tagtatgtca
    22141 cttttcagtt acggaacaag tttaatataa aaattatcaa aaaaacatag gcaataaaga
    22201 gaaaaattaa tttatcatag attagaaata atatgacaaa acaattcaat gatgttaatt
    22261 caatagtctt ttgtttttta tcagagatac ttatggatag ataaataaga taggtttgaa
    22321 aagcgaagag aataataaag aatatagcct tcataaaatt tagctttcat ttttatgatg
    22381 tagcggtata ggctaaatat ccacaaacca ctgctcctcc aattcctcct attgcagcgc
    22441 cccatggtcc tagaattttc ccatatttca ctccacccgc tgcacaacct aaagcagcaa
    22501 ctacagctgc tcctccaaca cctgctttgg caaaatctcc ccaattgcat ccgccacctt
    22561 caacgcaagc aagcatttca gtatccataa cagaaaattg tgacatcatt tttgtatcca
    22621 tgacaaatac tcctttttta aaaaactaaa ataaatcaga atagaatcct cataatttta
    22681 ctataagtct taccaactta gtcccaattt atcaccaacc atacctccta agcatgttaa
    22741 tccaccccca attgcaccaa tgtgtgctcc aacaaatgca ccagcaagtc cagctactcc
    22801 taaagtggcc aaacctgctc cagttccacc agttataatt cccgtagtga ctcctgtaat
    22861 cagtgcattt tgacaatcag tggagctata ccccccttca actttcgcaa gcatttcagt
    22921 atccataacc tctaactgtg acaacatttt tgtattcatg atgaatacct cctttttatt
    22981 ttcaatttgt taccaaagtc ttaaattcaa taaacaaata gatttttttt agtatctttt
    23041 tgattttctt aaaaaagtat atacgtctac tatcttctta aaggtagcag tacctatttt
    23101 ttagtctaag atttcaataa tcttgagtat ctaaaatatc ttaatttcgt tattctcctt
    23161 gcaataaaaa gttttactat actatttatt aacttgcaga aagcaaaaaa tattagtaaa
    23221 taatagttta tagttaagtt ttttattcct accaatccat caactaagta aagcatcaac
    23281 gattacataa acgattgata atataattaa aattttgcta actatcttat tctcatgatt
    23341 cttagataac tttgatattt tgtaagtaag taaataagac agtaaattaa tagcgataat
    23401 aatactatat ttaagaatca taatcttaca aagaggacat aattcctgaa cctacacaaa
    23461 taagtgttgc tgctccccca gttatcggac cagtcgcagc agctaatagt actgctccaa
    23521 tacaaccacc gattgcagat cctaaattgc ctcttcctcc actaactatt tcgagttctt
    23581 cattatccat aacagaaaat tgttccatca tttttgtatt catgacaaat actccttttt
    23641 tcttttttta tttttgtctt gttgtaactt tgataagttt agtatatcat cgttttttaa
    23701 aatttttcat ccagatcttg aattgtcatc gaaacgtctt gaattaggtt ttttatttca
    23761 agccacctct aaatgtttaa aaaaaataat ttctaatcac ttttttacca ttcaggaagt
    23821 tttaatgact attcaagatt tcataaaata tgaacttagt tttatgacat aatagaccta
    23881 tccactatat gaaaggaatt gccaatgact tcttataaac gtacatttgt tcctcaaata
    23941 gatgcgagag actgtggtgt cgctgcctta gcctcgattg ctaaattcta tggttcagat
    24001 ttttctctag ctcacttgag agaacttgca aagaccaata aagaagggac gactgctctt
    24061 ggcattgtaa aagccgctga tgaaatgggc tttgaaacaa gacctgttca agcagataaa
    24121 acgctctttg acatgagtga tgtcccctat ccatttatcg ttcacgttaa caaagaagga
    24181 aaactccaac attactatgt tgtctatcaa acaaagaaag actatctgat tattggtgat
    24241 cctgaccctt ctgtaaaaat cactaaaatg tcaaaagaac gctttttcta tgaatggact
    24301 ggagtagcta tttttctagc taccaaaccc agctatcaac cccataaaga taaaaagaat
    24361 ggtctactaa gcaagcttcc ttcctctgat tttcaaacaa aaatctctca ttgcttacat
    24421 tgttctctca agcttattgg tcactattat caatataggt ggttcttact atctccaagg
    24481 aatcttggat gaatacattc caaatcagat gaaatcaact ttaggaatca tctcagttgg
    24541 tctggttatc acctatatcc tccaacaagt catgagcttc tccagagatt atctcctaac
    24601 cgttctgagt cagagattaa gtattgatgt gattttatcc tatattcgcc atatttttga
    24661 acttcccatg tctttctttg cgacacgtcg tacaggagaa atcatttcac gattcacaga
    24721 tgctaactct attatagatg ccttggcttc taccattctt tctctttttc tggatgtttc
    24781 tattctgatt cttgtaggag gcgtcttact ggcacaaaac cctaatctct tccttctttc
    24841 tcttatttcc attcctatat acatgttcat catcttttct tttatgaaac ctttcgaaaa
    24901 aatgaaccat gatgtcatgc aaagtaattc tatggttagc tctgccatta tcgaagatat
    24961 caacgggatt gaaactataa agtcgctcac gagtgaagaa aatcgctatc aaaatataga
    25021 cagcgaattt gtagattatt tggaaaaatc ctttaagctc agtaaatatt ctattttaca
    25081 aacgagttta aagcagggaa caaaattagt tctgaatatc cttatcctat ggtttggcgc
    25141 tcaattagtc atgtcgagta aaatttctat cggtcagctg attaccttta acacactttt
    25201 ttcttacttt acaactccta tggaaaatat tatcaacctc caaaccaaac tccaatctgc
    25261 gaaggtcgct aataaccgtt tgaacgaagt ctatctagtc gaatctgaat ttcaagttca
    25321 agaaaaccct gtccattcac attttttgat gggcgatatt gaatttgatg acctttctta
    25381 taagtatggt tttggacgag ataccttaac agatattaat ctcacgatta aacaaggaga
    25441 taaggttagc ctagttggag ttagtggttc tggtaaaaca actttagcca aaatgattgt
    25501 caatttcttt gaaccctaca aaggacatat ttctatcaat catcaggata ttaaaaacat
    25561 tgataaaaaa gtcttgcgcc gtcatattaa ttacctacca caacaagcct atatctttaa
    25621 tggctctatc ttggaaaact taactttggg cggtaatcat atgattagcc aagaagatat
    25681 tctaagagct tgtgaattag ctgaaattcg tcaagacatt gaaagaatgc ctatgggcta
    25741 tcaaactcag ctctctgatg gagctggtct atcaggagga caaaagcaac gaatagccct
    25801 cgctcgtgct cttttaacta aagctcctgt tttaatacta gacgaagcta ctagcggtct
    25861 tgatgtcttg actgagaaaa aggttataga taatcttatg tctctaactg ataaaaccat
    25921 tctctttgta gcccatcgtc tcagtatagc cgaacgaacc aaccgtgtca ttgttcttga
    25981 ccaggggaaa atcattgaag ttggtagtca ccaagagtta atgcaggcgc aaggtttcta
    26041 ccatcatcta ttcaataaat aaggagaatg tcatgaatcc taatcttttt agaagcgtcg
    26101 agttttatca gagacgttac cataactatg cgacagtgtt cattatacct ctttcattac
    26161 tatttacttt catcttgatt ttctcccttg ttgccacaaa agaaattact gttacttccc
    26221 aaggagaaat cgcccctaca agtgtcattg cctccattca gtcaaccagt gataatccta
    26281 tcctagctaa tcatttagtg gcaaatcaag tagttgaaaa aggggactta ctcatcaaat
    26341 actctgaaac aatggaagaa agtcagaaaa ctgccttagc aactcaatta caaagacttg
    26401 agaagcaaaa agaaggactt ggaattttga aacaaagctt agaaaaagcg actgatcttt
    26461 tttctggcga ggatgaattt ggctaccata atacctttat gaattttact aaacaatccc
    26521 atgatattga actgggtatc acaaagacta acaccgaagt ttcaaatcaa gctaatcttt
    26581 ccaatagcag ttcatcagct attgaacaag aaattacaaa agttcaacaa caaattggag
    26641 aatatcaaga gttgagagat gctatcataa ataacagagc acgcttacca actggcaatc
    26701 cgcaccagtc aattttgaat cgttatcttg tagcctcaca aggacaaaca caaggaactg
    26761 cagaggagcc atttttatct caaattaatc aaagtattgc aggtcttgaa tcatctatcg
    26821 caagcctcaa aattcagcaa gctggtatcg gaagtgtagc aacttatgat aacagtttag
    26881 caaccaaaat tgaagtactc cgcactcagt ttttacagac agcctcacag caacaactaa
    26941 ctgtggagaa tcaattaaca gaattaaaag tacaactaga tcaagccaca cagcgtttgg
    27001 aaaacaatac cttaacctcc ccaagtaaag gtatcgttca tctgaacagc gaatttgaag
    27061 gtaaaaatag aattccaact ggtacagaaa ttgctcaaat attccctgtc atcacagata
    27121 caagagaagt actaatcact tactacgtat cttctgacta tctacctcta ctagataaag
    27181 gacaaactgt aagattaaaa ctggagaaga ttggaaatca cggcaccacc atcatcggcc
    27241 aacttcagac aattgatcaa actcctacca gaacagagca aggaaatctc tttaaattaa
    27301 ccgctcttgc aaaactatct aacgaggata gtaaactcat ccaatatggc ttacaaggtc
    27361 gcgtcactag tgtaactaca aagaaaacat attttgatta tttcaaagat aaaattttaa
    27421 cccattctga ttaattttca gataacactc tataactatt tattatctta tcaaaaagga
    27481 gaatcataac atggataaga aacaaaacct aacttcattt caagaactaa caactaccga
    27541 actcaaccaa attacaggtg gaggattgtg ggaagattta ttatataaca ttaatagata
    27601 tgctcattac atcacataag aacttcatca tccaatacaa ctataaaaaa ataagaccga
    27661 gaaacaagta ctctcggtct tatttttcat cattctgtat gtatcacagt aagtacctga
    27721 cgaaagactt gattttgaca ggtggtattt agactggtat taggatggct ttccacaatc
    27781 ttcatgacgg tatagagacc aactcctctc tcctcccctt tagaactggc tccaaaggag
    27841 aagatttcag aaatatcgat gccctcttct ttgatggagt tttcgatgat aaaggtctcc
    27901 tgtgctccat tttttaaaaa ggcgattgaa acatgaggtt gactagcttc cacactggct
    27961 tcaatagcat tgtcacaaag gatagacaca atggttagaa aatcaagtag actcatcccc
    28021 tcgacctgaa tctcctcagg aacttcgaca ttaaagacaa tgttcttatc tctggctttt
    28081 aaaaatttcc ctgctagaag acttttgagg gctttatcac gaatatttac caatctgccc
    28141 aggtcatatt tattgttctg caatttctga ctggaatcct ttaagacgga gccatagacc
    28201 tcttttatct gctccatatc ctcctcttca atgcccagac gtaagctagt caagaggttg
    28261 gtataatcat gacgaaagct ccgtacttcc ttgtaaagct cctctatatg ccgactatag
    28321 cgttccatat ctctatagcg cagggcctgc tcttgttcca atctctcata gagtttttcc
    28381 ttcaaatagg tatccaattt cttgataacc cccataaaaa agagtaggta aaagactagg
    28441 atgagatggc gaacagtctt tgattgaata ctttgttcat attcaaaaaa agacagactt
    28501 tccatgacta gatagtagcc acccattatc cagttaatct gagtcaggga cttttgaaag
    28561 gctttatcga gaatctcctt tctcaagcta gtaaaatcgt agtccaacca tttcaaaaaa
    28621 gctagagaaa tgaagaaatt gaaaattatt atacataacc cagtaaatga gtagccatca
    28681 tatacttgcc cttgtcccaa aaatggaagc acaaaatagg agactcctct ataaaagaga
    28741 ttcaccaata tcattggaaa gagaccataa aagaaaagga gttttttagg aagccctctc
    28801 aataataaga aagataagcc tatgccgtac aagggttcca taaaataaga taggtaaaca
    28861 tttcctacta tatagctaat catcacaaaa acaaaggcca acagtatctt aaaaagaaag
    28921 gccttaaaaa tcctctcgaa agtaagatca attccatcca ccttaaagaa gatgacaatt
    28981 tctagtccat tagtaacaag tgtatacaac aatatccaag caatgttcat aaattctcct
    29041 agctcagtgt aatttattga tggcctcaga cacttccctg accttataac gggcgattag
    29101 acaacttcca ccattgggaa agaaaagcag tttttctttc ttatccaaat gcaccacatt
    29161 tgcaggattg atgagaaaag agcggtggca ctgcaagaga cggggctcct gcttgaaaac
    29221 ctcctctaaa ctcgctgtaa attccagcct gtctgtcttg gtatagagaa taacacgatg
    29281 ggctctgggc gacgtttcga gatagtaaac ctctttaaaa ggatactgaa attgggcaaa
    29341 ttttgattta aagtaaaagc aatcttccgc cagactttta ctatcttgac tattggcata
    29401 gaggagggct gtctcgatcc gagattcaaa ctcctctgct gacaaggcct tatcaatgta
    29461 gtccaaagca gacacttggt agcgaaaaga caggggcata aactccgagt gagtcgtcac
    29521 aaagacaatc agggcataag gatcccgatc ccgaatcttt ctagccactt ccagtccctt
    29581 catctcttca tttcgaatct caatatccaa aaagaatagc tgatgggccc ccttctcatg
    29641 cacttcagcc agcagttggt ccggcttgcc aaatacctca aaagagctag gaatgatatg
    29701 atgtgctttc aaaagtttct caatcgtcgt ttcaattcta gtctgttggg aaaaatcatc
    29761 ctctaaaaca aatattctca tcttcttact ctccctcttt caaccatttt tgacgaattt
    29821 ctctatagcg acgtctggca tacttgacag cgtattgacc ttcttctccg agaaaaagga
    29881 ttctttcttg aaaatcaatc gattttaatt tatcaagatt aaccaaacaa tttcgatgac
    29941 atctcatcaa ggtttcccca cattggttct caagattact taaattttga agcatattaa
    30001 aactagcttc ttctgtaaca atctgtacgg tatgggcttt agttggatgt gtttggatat
    30061 agtagatatc gtcgatgttt actttataga ctgttttctg cgtctgaata atcatatatt
    30121 tcattggatt ctcctcctaa gaaaagaata acagaaaagg tctagcccaa gcacacccaa
    30181 tcctaaacag tctttgaaaa ctcctaaaag gattattttc tacaacatca tgatgagctt
    30241 acaactattt tatcataaaa ttcactcagc gcaattcaag acatttcaat gacaattaaa
    30301 gatttgaata aaaaaaaaga attaaaagtg ataaactaac agtatcaaaa cacagttgcc
    30361 agaagtaaga ctggcaccca gattaaagga ggcattccca tgacagatac agaccccatc
    30421 aaaagagctc atactttgat tactgactta aacaaagcct accaagcatg caaacaggca
    30481 agcgctgacg acgtccgctt tcaggagcaa ttaaactcta ttcttggttt tctagccaag
    30541 gctgaaacag tggataatcg attcttgatt gaactagaaa aattttacca gacttccagt
    30601 cttctcatgg gactcagcgc tcttgatcca gatgctccaa ctcgcgccgc ttggcgggcc
    30661 tatgaccgct tccactttga ccaagtcaag accaagttaa tactcaatga aaatcaaaga
    30721 gcaaactagg aagctagccg caagctgtac ttgagtacgg taagacgacg ctgacgtggt
    30781 ttgaagagat tttcgaagag tataagtctc tacggaccaa ccattatcct gtagtaacaa
    30841 aaaagaagtt gagacagact gaactcaact tcttttttag tgtcgtatca gcaatgttag
    30901 tcctgcatct gacgttttac ctgataaggc aaatacaaga ctagtaaaac caaaccagct
    30961 cctagtaagg ctagaagggc tagtttttct tggaaggtaa tcaacccaac aactaattcc
    31021 acaagtaaaa caaaactggt caatcctcga actacctcct gtaagccttt ttccttttgc
    31081 cccttgtcca gcggaaagag ttgggtcaaa tactggtagt caaaggcatg atagagggcc
    31141 agcaactgga agagcaagag gtagttaaag agaactacca ctgctgtcgc aatccaagct
    31201 tgctcgataa aaacctgcgc cagtacggaa agtaagagaa gacgaagact gagagcaaag
    31261 aggtcgccat ttcgcagata agaacgcaga tagagatttt gccaaatctt tccagacacc
    31321 ttctgaacag cctttaagat aaagtccaga taggcacgac gtttgacact gtttgaaatt
    31381 ccctttacct gcgtaaagag ggcaaagaaa cgaagcaaga cttgcttacg cttgctttct
    31441 tgggaaatga catagtccca gtccagccca gtttcagtga aaaatttgct ggccttttga
    31501 cgaaagtgga aatattttcc tacccccaat aaaagcacat agagcagaaa aactggcaag
    31561 ccataaccca ttgctaaaaa taaaggcgca aataacagca agaaaagggt ctgtacaaag
    31621 agccaaaaga ctagggaaat gccagtttga cgcttgagat ggagcttgat ttcctcttct
    31681 ccaactaaga gaaagagctt gtctggagcc tccatatagg tggcaattcc tccccaaagt
    31741 aaaagtaaaa cagacgtaat tcctacaaac aaaaggatag gccaatgatt ttcaggaaaa
    31801 tgttgtaaga gttgactgta ctggtaggct agaaagccca acaggacaag caggaacaag
    31861 acaaagtggt cattgagcac atagcgcaga taaccaaggc actccttacg aaaggcctgc
    31921 tttctcttta aaaacaagtc tttcatagat cctcctcttt ggtcagagcc aagtaaatat
    31981 cattcaaact agcctcaggc atatcaaagg cttcacgtag ttgcaggaga ttgcctttgg
    32041 cacgcacctc tcccttgtga agaatgacaa aggcatcaca catcttctcc gccgaatcca
    32101 gcacgtgggt actcatgaga atagacttgc ccttttgctt ctccacttcc aaaagctgaa
    32161 tcaaatcaga aatagccagc ggatcaagac caaggaaagg ctcatccacg atgaaaagac
    32221 ttggatccac cacaaaagca cagataatca tgaccttctg cttcatccct tttgaaaaat
    32281 gaacagggaa ccagtctaat ttctgttcca aacggaacat ttttaacaag ggctctactc
    32341 gttcgaaagc cactttttgc tcaataccgt aagccatagc aaccgtttcg atatgctctc
    32401 tgagggtcaa ttcctcatac agactaggcg tctcaggaat gtagccaatc tgcttgcggt
    32461 agctagtcgc atctccttgc agagtcaggc cattgatatt gatggagcca ctataaggtg
    32521 ccaacagacc gataatctca ttgatcgtcg ttgatttccc agcaccattg agaccaatca
    32581 aaccgaccaa ctgcccactt tcaacagtaa aggacacatc tttcaaaaca gggacatgaa
    32641 catagccacc tgtcaggttt ttaatttcta acatattttc tccaaatctg gtataatgta
    32701 gctatattat atcaaaattc agtacagtag aggtagattt tatgtcagat tgcatttttt
    32761 gtaaaatcat cgcaggggaa attcctgctt caaaagtata tgaagatgag caggtccttg
    32821 cctttcttga tatctctcaa gtaacactag gacacacctt ggtcgtgcca aaagaacact
    32881 atcgcaatct tttggagatg gatgctacga gcgccagcca actctttgcc caagtaccaa
    32941 aagtagctca aaaagtcatg aaagtcacta aggctgctgg tatgaatatc atttccaact
    33001 gtgaagaagt cgctggtcaa acagtttttc atactcacgt tcaccttgta cctcgctaca
    33061 gtgctgacga tgacctcaag attgatttta tcgcccacga accagacttt gacaaacttg
    33121 ctcaagtcgc tgaaaccatc aaaaacgctt aaggagttgc tatgaaatta tccaacctac
    33181 tgctatttgc aggagctgca gccggaagtt atctggtcac aaaaaatcgc caaaccatca
    33241 cagatgaagt cttgaatacc actgaccgcg ttcaagctat caaggacgat gtggatatta
    33301 tccaaaacag cctgcaaatc attgaccagc aaaaagaact tatcaaggaa taccaagaag
    33361 acttgactta caagtttaag gtcttggaaa aggatatcca gactagacta gctgtgataa
    33421 aagaaatgca gggaactgaa gataagtaaa aagagccccc cggctctttt ttaaaacgta
    33481 aacaagttat agtgaattga atttagaata gcacatcata gtttctaaag cattgttaga
    33541 gattacttta aaatcctctt atcaatttgt tcatattcta tttcaatcta ctatatatat
    33601 cccatcaact atgcatcata atttaggtaa ctcatactca ataaaaatca aaaagcaaac
    33661 tagaaagcta ggcacagact gctcaaaaca ccgttttaag gttgtggata gaactgacga
    33721 agtcagctca aaacactgtt ttgaggttgt agatacgact gacgaagtca gctcaaaaca
    33781 ctgttttgag gttgtggata gaactgacga agtcagtaac catacccatg acaagccgac
    33841 gctgacgtgg tttgaagaaa tttttgaaga gtatcattca ccatttcaca actaaatcga
    33901 agactttctg ccgtaatgaa aacacctgaa acagcttggt ttcggctgtc cggaaacttt
    33961 aagacttagg ttcaaagttt aggtatggaa cttcgaagga ggtcgctacc gtccgtcatt
    34021 acttaggaaa gtcttaaaaa atcggctcta taaagtaaaa agagcccgac agctcttttt
    34081 gtttatattc aatgaaaatc aaaaagcaaa ctaggaaact agccacgggc tgctcaaaac
    34141 actgttttga ggttgtagat acgacaagcc gacgctgacg tggtttgaag aaatttttga
    34201 agagtattat tctccatcaa aggcatcttt aatatggtca aagaagcctt ttttctttgg
    34261 atttactttc aagtcaccag cagccgcgaa ttctttcaag gctacttttt ggcggtcgtt
    34321 caagcctgtc ggtgttacga cattaacagt aacgtattgg tcaccaactg caccgccacg
    34381 aaggctcggt gcccccttac tacgtaggcg gaatttctta ccagtctgag ttccctctgg
    34441 aataaccaat tcaacatcac cgtgaacagt tggaatatct actgtatcac caagagccgc
    34501 ttggacaaag ttgaggttga gattgtagaa gatagtcgtt ccttcacgtt caaacttgtc
    34561 gctagcttct acagaaacta ctacatacaa gtcaccataa ggtccaccgt taaagcctgc
    34621 ttcaccttga ccagcgaggc gaatttgttg acctgtttcc acaccagcag ggattttcac
    34681 atgtacgcta tgagcttgtt tctcatgacc tgttccatga caggttgtac atggatattt
    34741 gatttctttt cctcgaccgt gacagacatc acaggttact tggcgacgca tcataccaag
    34801 aggagtctgc gtatcgacgt taatgacacc agcgccatga cagcgtccac aagtgactgg
    34861 acttgtccct ggcttagcac cagagccatt acatgtacga cagccagctt cacgatgata
    34921 cttaacttcc ttctcagttc cgaagatagc ttcttcaaag gtcaaattga cacgatactg
    34981 gagatcatct ccttggcgag gagcgtttgg attgcgcgaa gaaccgcctc cgccgaagaa
    35041 acttgagaaa atatcctcaa aaccaccgaa accacctgcc ccattgaaac cgccgaaacc
    35101 accagctcca ccaaaaccac cattggcgcc tgcagcacca tactggtcat aggcagcacg
    35161 tttttggtcg tcactcaaag tctcataggc ttcttgaact tccttgtact tgtcctcagc
    35221 accaggctcc ttgttgatat ctgggtgata ttttttggaa agcttacgat aagccttttt
    35281 gatttcgtct gccgaagcgt ttttggatac ccccagacga tcataaaatt cagtattgtt
    35341 cataattcaa gatacaaagg gcgtcaaacg gacacagcca tctaggagtt ttgacgacgg
    35401 acgcttacgt cctagaaaaa actatctttt gggcacagtc cgtagcccgt gttcagttac
    35461 gaacaccctt attcctttct attgatgttc tgaatcgaac caccatttag gtcgggttca
    35521 attcctttct tttatattta gtaagaaatt ctgaaacccg tgttcagtta cgaacactct
    35581 ttgttccctt ctattgatga gacaaaaccc aaacaaatga gattccgtcc ctttttatcg
    35641 aaaaacagag gctgggttgc aacctctgca aataagtaaa ttaactttat tttgatttta
    35701 aatatcctat aagtacagaa atatttatat atttttgtct cttcttagta tttgcctata
    35761 taattccaat tgatcataag aaatacaact actgtccaaa tcataccaat tatgaacggt
    35821 attacaaatt tatatgtttg tatttctaat gatatcatag ctggtaccat cgccgataca
    35881 aatgcagaca acaatactga ggtaacaaaa ttccttaccg cttcatcatt tttgatacaa
    35941 ctatcatgtt cagctaatat aatttctcta tatctagcta aatattctat tggaatatta
    36001 tcaataaaat cttttgatgt tctatagtta tcagcttgat tacaaaaatc attataaact
    36061 tttcgtgtat tttttagata ctcttcatcc aatacactca tcttactttt ccgtaaactc
    36121 tccgtctacg acgtcatcgc ctgcgttccc tgttgcttgt gcgccttctg ctccttcttg
    36181 agcttgttgc gctgctgcgg cttgttcgta gagtttaaca gcaagtcctt gagctttttc
    36241 gttcaatgct tcaagttttg ttttcatgtc gtccaagttg ttgtcttctt gagctttctt
    36301 aaggtcatca agggcagctt gggcagcgtc acgttctgcg tcgaagcctt taccttcagt
    36361 ttccttgatt gtcttttcag tcgcaaagat tgcttggtct acttcattac gaaggtctac
    36421 ttcttcttta cgtttcttat cggcttcagc gtttgcttct gcatctttca tcatgcggtc
    36481 gatttcttcg tcagtcaaac ctgagttcga ttggatgaca atagtttgtt ctttttgagt
    36541 tccaaggtct ttggccttaa cagacacgat accgttcttg tcgatgtcaa atgttacttc
    36601 gatttgagga attccacgag gtgcagctgg gatatcagtc aattggaaac gtccaagagt
    36661 cttgttatct gctgccattg ggcgttcacc ttgaagaaca tggatatcaa cggctggttg
    36721 gttgtctgct gctgttgaga aaacttgtga tttagatgtt gggattgtag tgttgcgatc
    36781 gataagtttt gtaaatactc cacccattgt ttcgatacca agtgacaatg gcgttacatc
    36841 aagaaggaca acgtccttga catcaccagt aatcacacca ccttggatag ccgcacccat
    36901 agcaactact tcatcagggt ttactgattt gtttggttct ttaccagttt cagctttaac
    36961 agcttcaaca acggcaggga tacgagttga accaccaaca aggataactt cgtcgatttc
    37021 tgacaagctc aaacctgcat ctgaaagggc ttgacgaact ggaacttttg tacgttcaac
    37081 aaggtcacga gtcaaatcat caaatttcgc acgagtcaaa gtcatttcca agtgaagagg
    37141 tccagcctca cctgcagtga taaatggcaa gctgatttgt gttgaagtta caccagaaag
    37201 gtctttcttc gctttttcag ccgcatcttt caaacgttgc attgccatct tgtcagtaga
    37261 caagtcgata ccgttttctt tcttgaattc tgctaccaag tggtcaatga ttttttggtc
    37321 aaagtcgtca ccaccaagtt tgttgtcccc tgcagttgac aatacgtcga agacaccgtc
    37381 acccaattca aggatagaga cgtcgaatgt accaccacca aggtcaaata ccaagatttt
    37441 ttcttctttg tcagtcttgt ccaaaccata agcaagagct gctgcagttg gttcgttaac
    37501 aatacgttct acttcaagac cagcaatttt accagcgtct tttgttgctt gacgttgagc
    37561 gtcgttgaag taagctggaa ctgtgataac agctttggtt actttctcac caaggtagtc
    37621 ttcagcgtag cctttcaagt attgaaggat catagctgag atttcttgtg gagtgtattc
    37681 ttttccattt gcagaaactt tttcagaagt tcccatctta gatttgatag agataactgt
    37741 atctgggttt gtgactgctt gacgttttgc agcatcacca acgatgattt ctccgttttt
    37801 gaatgagact acagatggag ttgtgcgatt cccttctggg tttgcgatga ttttgctttc
    37861 agttccttca agaactgcaa ctgctgagtt tgttgtacct aagtcaatac cgataatttt
    37921 agacatgtgt ttttctcctt gttagttaat tttctatttt tctttttgat actcttctta
    37981 agtggcgacg ccgtcagagc ttgacttcgt caatctcttt gactaaactt tgagcctaag
    38041 gtctcaaaat ttgcgcaaat agcaccacgg cgaagagtat cgtctttggt tcgcttcgct
    38101 cactattaca aagccaaaca tattttatct ttcttcatag tttattgtcg tttcggacaa
    38161 gttttctatt atgtaaattg cgacacgagg agtcgaaatc gattttattt cgacgacgag
    38221 ttagtaagga agctaggcaa acgtcatagc gattgccgtt ttctgacgag ttgctttagc
    38281 taccgtcaga attgccgaat cgaacacgcc ctaagctctg agtaaaaaag atagattttc
    38341 ttgtgttcat cgaacacttc gtcaatctcc tatttttact gcgagctttt tacgagcttt
    38401 gtatcttagt tatacaccac taccattgct gggcgtagga tgcggtcatg gagtttgtag
    38461 cctttttgaa agacttgggc gatggtatct actgggtgtt catcgtctgc tgggagagtt
    38521 tggatggcca tatggtagtt atggtcaaat tcgccatctg ctgcgatttc ttcaattcct
    38581 tcttctttca aagcgtgaat caagctttct tgcaccatcc ccaagccctt cttcacatca
    38641 tctgtcaaac cttcaactgc aagtgcacgc tcaaggttgt caagagatgg taagattgct
    38701 tttgccaagt cctggctacg ataacgttgc aagttttgac gttcttcatt ggcacggcgt
    38761 tggatatttt gcatttctgc atgagcgcga agatatttgt tttcgaactc atctgcacgt
    38821 tcatttgcca agtccaactc agacttttca ggagttgttt cttcagctgt ttccacaact
    38881 tcctcttctt gaacttcttc tacttcttca ttttttatat cttgggccat gttcgcctcc
    38941 tttaatgatt tcaatcttaa tgtacttcgt aatgattact gctgaggtag cggtaaaaat
    39001 ctgtcaactt catggtcaaa acacggttga ccacattgat ttgattgatt agctgttggt
    39061 aatccagatt aactggaccg ataatggcta gaattccaac tccccgataa ggaatgagga
    39121 acttactact aatcaccgct aggtcagcta aacaggactc ttgaccgtct gcaacacgaa
    39181 cattttgcat ctgatcctca cgcaacccct cacgaatctc caaggccacc ttttgcggtt
    39241 ggtcaaagaa ctgataggct gctagattgg caaaattcaa gagattgacc ttgcccgcca
    39301 tcacaatgtt ttcgttgaac atttccttaa agatgtgttc aaagagatcg atgacattat
    39361 ccgttgttgt aaagtaacgc tggataatct gcggaatctc cgtccgaatc ttgtagtgaa
    39421 tatctaaaac ggtgtgaccg aggaaacgtt cctgaatgat gctcttcagt ttcagcaaat
    39481 cctcctgcaa gaagttcctt ggaatcagaa actgactagt aaccgttcgc gactcgtcta
    39541 gggtaaatac cgccaaggct gtatgttgcc ccaaaacaac gatatcaaag gctgtcaaac
    39601 gttgcctgct cggctcaaca tccagtgcca ctaccgtaca gccactcagg tctgttagca
    39661 agttagcagc ctcttgcaga atatcctcca atttgaagaa ttcctgatca aaggctttga
    39721 caatctcata tacctcattt tcagccagtc ggtcaaaatc cagtgagtgt ttcacatagt
    39781 actgaaaacc agcaacactt ggcatccgac cgcttgaagt atgagccttc tcaagcaacc
    39841 cttgtttttc tagttccgcc atgtcattac gaatggttgc actgctagag ttaatagact
    39901 cttgcaaggc ttttgatccg acaggttcgt gcgttttggt aaagatgtca ataatcagat
    39961 ttaaaatatc ctgctgacgc tctgtaacca tctcatcact cctctctgtc tgatcaatta
    40021 gcactcaatg catccaagtg ctaacttatg attctattat acacccttag aagagaatgt
    40081 caagacaaaa actcaaaaaa ttagcactct tttataaaga gtgctaaaaa tcaatctgaa
    40141 gacctagaac cttgctattc atctactcgg tatttccttt ttagtctgaa ataaccatga
    40201 attagataag aaatcagaaa agcatataaa acaaaaataa gaaagaaaga catagaaaga
    40261 tcctctctaa acaaactcat acaaacaaca agaccaccta agaaagtagc tatacaggaa
    40321 cgaagtctag atcgcataac ttcccatttg agccccttac tcatatagac ttgatcctct
    40381 ggaagtaaat cagaagacga tttacgaaga atcgaacaag aacctgctcc tatcaattcc
    40441 caacctctat ctctaaaatc ttgcagttca cgcttatgct ctttaagaaa tctagaatca
    40501 tagatacgat agataacatc gtccggttga ccttgctcaa aatagaacaa accaaaacga
    40561 ctagttctat acctccaacc tttcaaatgc atctcatgta aatattcttc tttcttgtcc
    40621 aaatcaacaa tggtgaaaat ccgaaattct actctgctat tcattgtctt accccaaaat
    40681 tagaaaacat gcctagcgtt atttattaga taattctttc cacttttgac tcaatctcca
    40741 aaaaatataa gaaatctgaa tcgcaaaaac tatcaataaa acccaatcta ttatgaaaat
    40801 caaaaacact tcccaactga aagaactacc tccagtgaca aactttgaga aaaacggtag
    40861 tagagctaaa aagagaagca aaataggaag catccgcatt gttaaaatcc ttttggcata
    40921 aaaaaatctt tatttaaacg aaaatattat ggcaaaattt acgccagttt ttgaacggct
    40981 gatgtagata ttttatactt tcaaaatgtt taaatgtgat tatttatttt tgaaaaatag
    41041 ctcaccagcc cgactgaaag tgcttataga atgataataa gtcgcctgcc gaaaacagcg
    41101 aaaaatagca gtgttatgcg gagataatct gacgcgatgc gaaagtatat tgcatactta
    41161 ttttcaacaa tttagcagag tatttttata agtgtgatat aatagaagta taatttgttc
    41221 tgatagttta ttttatggag aagtagattt ttagaatgcg gaggattcaa tatggttgag
    41281 tttataaagt ctaagaaaga aatgagtgag gaggatatta aagcaaattt catcactcct
    41341 gctattgtat ccaaaggatg gaaaaatggt gagcatatcg cttacgaaga atacttcact
    41401 gatggtcgaa ttgaagttag aggagataag gctcgtcgta aagaaggaaa aaaatcagac
    41461 tattcactgt attaccaatt tggaactcga attgcaattg ttgaggcaaa ggataataaa
    41521 cacagcgttc gagcaggatt acaacaagct attgaatatg gagagatttt agatgttcca
    41581 tttgtttatt cttcgaatgg tgatggcttt attgaacacg accgtatcac gagagaagaa
    41641 cgtgagctgg agttagacga attccctact cgtgaagaat tattttctcg tatgacgaag
    41701 gaaaaaggat tgacgtacga aattacagaa gctatctcaa ctccatacta tacagacgcc
    41761 ttctcaatga aaacgccacg ctattatcag caaatagcta tcaaccgtac tattgaaaca
    41821 gttgccagag gacaaaaacg agtaatgttt gtgatggcaa caggaacggg gaaaacgttc
    41881 atggcttttc aaattattca tcgccttcga aaagctggtt tggctaaacg agttttattc
    41941 ttagcggata gaaacatctt agtagaccaa acgatggctg aagactttaa gccattcgaa
    42001 aaggtaatga cgaaaattac accaaaactt ttgactgctc ctgaaaaatt aaattctttt
    42061 gaaatttatc tagggcttta tcagcaacta actggtgaag atggaactga aacacattat
    42121 caaaaatttg ataaagactt ctttgattta atcgtaattg atgaagcgca ccgtggttca
    42181 gctaaggaaa acagtaactg gcgtaagata attgattatt tcagttctgc gacacagatt
    42241 gggatgaccg ctactcctaa agaaaccaag aatgcttcca atacggaata ctttggtgag
    42301 ccaatctata cttatagttt aaaacaggga atcgaggatg gttttttggc tccatatcgt
    42361 gttatgaggg ttaatttaga tgtggatgtg gatggttatc gtccagaaac tggaaaagtt
    42421 gatactaacg gacaattaat agaagatagg tactacggca ggaaagattt tgataaaacc
    42481 attgtcattg atgatagaac gcaaagagtt gccaagtttg tttctgatta tatgaagcaa
    42541 aacaatgcac gatttgataa aacaattgtt ttttgtgttg atattgacca tgccgagcga
    42601 atgcgtgctg cacttgtaaa agagaatcta gacttagtcc aagaagacta tcgttatgtc
    42661 atgcaagtaa ctggtgacaa cgctgaagga aaagctcaac tggataactt tatggatgtc
    42721 aattctaatt ttcccgctat ggtaacaacg tctaaattat taacgacagg agttaatgct
    42781 aaaacatgtc gtttgattgt tttagactct aatatccaat ccatgactga atttaaacaa
    42841 attattggtc gtggcacacg tctttatcct caaaagggga aagaattttt tacgattatt
    42901 gattttcgaa atgttaccaa tttgtttgct gaccctgatt ttgatggtga gccagtgaag
    42961 gtgctggaaa caggtgcgaa aacagtcagt ggttccacgc ccggtttcgt agatgaggaa
    43021 ggtgacccag tagaaaaata tatcgttaca gacaagcagg ttaccattct taattctact
    43081 gttcaagtat tggatgaaaa cgggaaactg attaccgaaa gcctgaccga ctacactcgg
    43141 aagaatatct taggtagcta cgccactttg aacgatttta tcacagtttg gcatacggcg
    43201 gataaaaaga agcttatctt agacgaactt tataaaaaag gagtttatct agatgctatt
    43261 cgagagtcgg agggaatatc agaacaagaa atcgatgatt ttgatttact cctaaaactt
    43321 gcctatggtc aaaaagaatt aaccaaaacg gaacgtatca ataagctcaa acaaagcgga
    43381 tatttatata aatatagtga ggaagcgcgt gctgttttgg aaattttact gaacaaatac
    43441 atggataaag gtattggaga actcgaaagc attgaaacat taaaacttcc agaatttcag
    43501 atatatggtg gaaccttcaa aatcatcaat acttattttg gagataaaaa acgatattta
    43561 caagcaatta aagaattgga gcaagagcta tttacagtag cttaatgaaa ggaaagtatg
    43621 tcaattacat catttgtaaa aagaattcaa gatatcactc gaaacgatgc tggtgttaat
    43681 ggtgatgctc aacgtattga gcaaatgtct tggttattat tcttaaaaat ttatgatagc
    43741 cgtgaaatgg tttgggaatt agaagaagac gagtatgagt caattatccc agaggaatta
    43801 aaatggcgaa attgggctca tgctcaaaat ggggaacggg tattgacagg cgatgaatta
    43861 cttgattttg tcaataacaa gttattcaaa gagttgaaag agcttgaaat aacttcaatt
    43921 atgcctattc gaaaaacgat tgttaaatca gcttttgaag atgcgaacaa ctatatgaaa
    43981 aatggcgtct tgttacgcca agtcatcaat gttattgatg aagttgattt caatagccct
    44041 gaagatcgtc attcgtttaa tgatatttac gaaaaaattc ttaaagatat tcaaaatgct
    44101 gggaactcag gagaatttta tacgccacgt gcagcgactg attttattgc cgaagttctt
    44161 aacccaaaac ttggagaatc aatggcagac cttgcttgcg gaacaggagg cttcttgact
    44221 tcgactctga accgtttaag tagtcaacgt aaaactagtg aagataccaa aaaatataat
    44281 acagctgttt ttggtattga aaagaaagca tttcctcatc ttttagcagt tacaaatctg
    44341 tttcttcacg aaattgatga ccctaaaatt gttcatggaa atactttgga gaaaaatgtt
    44401 cgtgaatata cggatgatga aaaatttgac attattatga tgaatccacc ttttggaggg
    44461 tcagaattag aaacaataaa aaataacttt ccagcagaat tacggagttc tgaaacagct
    44521 gatttattta tggctgtcat tatgtatcgt ttgaaagaaa atggtcgtgt tggagttatt
    44581 ttacctgatg gttttctatt tggtgaaggt gtaaaaactc gcttgaaaca aaaactggta
    44641 gatgagttca acttgcatac gattattagg ttgcctcata gtgtctttgc accgtataca
    44701 ggaatccata cgaacattct tttctttgat aaaacaaaga aaacagaaga aacttggttt
    44761 tatcgtttag atatgccaga tggttataaa aatttctcga aaactaagcc gatgaagtca
    44821 gaacacttca atcctgttcg tgactggtgg gaaaatcgtg aagagattct ggaaggtaag
    44881 ttctacaaat ctaaatcatt tacacctagt gaattggctg agttgaatta taatttagac
    44941 cagtgtggct ttccaaaaga ggaagaggaa atcttaaatc cctttgagtt gattcagaat
    45001 tatcaagcgg aaagagcaac tttaaatcat aagattgata atgtattagc tgatattttg
    45061 cagttgttgg aggacaaata atgacaccag aacaacttaa agcaagtatt ctccaaagag
    45121 cgatggaagg gaaattagtg ccgcaaaatc ccaatgacga acctgcaagt gaattattaa
    45181 agagaattaa agctgaaaaa gaaaaactta tcagtgaagg aaaaatcaaa cgagataaaa
    45241 aggaaactga gatatttcgt ggtgatgatg ggaaacatta tgggaagttt gctgatggaa
    45301 gtactcaaga aattgatgtt ccttatgata ttcctgatac ttgggagtgg gtgaggataa
    45361 aatcaattta ttggaatttt gggcaaaata agccagagaa atcctttagg tatatagata
    45421 cgtctagtat tgatagaaaa aagaacataa tcaactacaa aaatctacaa tatctttcac
    45481 ctgaacaagc gccttcccgt gctagaaaat tagtttcgca gaatagtgtc ttattttcaa
    45541 cagttagacc atatctaaaa aatattgctg tagttagaga acttaaagag tatttgatag
    45601 ctagtacagc atttattgtt ttggatactt tacttaacga aacatatttg aaatattatt
    45661 tattatcaga taattttatc aatcgtgtta ataataaatc tactggaaca agttatcctg
    45721 caatcaatga ttataatttt aatctattat taatt
//
LOCUS       DAVHTH010000013        44900 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.013, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000013 DAVHTH010000000
VERSION     DAVHTH010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 44900)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44900)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44900
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.013"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            195..692
                     /locus_tag="VVR63_000726"
     CDS             195..692
                     /locus_tag="VVR63_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HEU6128767.1"
                     /translation="MLKSEKQSRYQMLNEELSFLLEGETNVLANLSNASALIKSRFPN
                     TVFAGFYLFDGKELVLGPFQGGVSCIRIALGKGVCGEAAHFQETVIVGDVTTYLNYIS
                     CDSLAKSEIVVPMMKNGQLLGVLDLDSSEIEDYDAMDRDYLEQFVAILLEKTTWDFTM
                     FEEKS"
     gene            692..2347
                     /gene="dnaX"
                     /locus_tag="VVR63_000727"
     CDS             692..2347
                     /gene="dnaX"
                     /locus_tag="VVR63_000727"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HEU6128768.1"
                     /translation="MYQALYRKYRSQNFSQLVGQEVVAKTLKQAVEQEKISHAYLFSG
                     PRGTGKTSVAKIFAKAMNCPNQVGGEPCNNCYICQAVTDGSLEDVIEMDAASNNGVDE
                     IREIRDKSTYAPSLARYKVYIIDEVHMLSTGAFNALLKTLEEPTQNVVFILATTELHK
                     IPATILSRVQRFEFKSIKTQDIKEHIHYILEKENISSEPEAVEIIARRAEGGMRDALS
                     ILDQALSLTQGNELTTAISEEITGTISLSALDDYVAALSQQDVPKALSCLNLLFDNGK
                     SMTRFVTDLLHYLRDLLIVQTGGENTHHSSVFVENLALPQKNLFEMIRLATVSLADIK
                     SSLQPKIYAEMMTVRLAEIKPEPALSGAVENEIATLRQEVARLKQELSNVGAVPKQVA
                     PAPSRPATGKTVYRVDRNKVQSILQEAVENPDLARQNLIRLQNAWGEVIESLGGPDKA
                     LLVGSQPVAANEHHAILAFESNFNAGQTMKRDNLNTMFGNILSQAAGFSPEILAISME
                     EWKEVRAAFSAKAKSSQTEKEVEESLIPEGFEFLADKVKVEED"
     gene            2375..2569
                     /locus_tag="VVR63_000728"
     CDS             2375..2569
                     /locus_tag="VVR63_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HEU6128769.1"
                     /translation="MNKQQFIIMALFTAAETYFFNEAWMTGRYIMAAFWAILLFRNFR
                     VSYVMGKIVDVIDQHFNRKD"
     gene            2719..3489
                     /gene="sufC"
                     /locus_tag="VVR63_000729"
     CDS             2719..3489
                     /gene="sufC"
                     /locus_tag="VVR63_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HEU6128770.1"
                     /translation="MSVLEIKDLHVEIEGKEILKGVNLTLKTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYEVTKGEVLFDGVNILELEVDERARMGLFLAMQYPSEIPGITNAEFLR
                     AAMNAGKEGDEKISVREFITKLDEKMELLNMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFALLDEIDSGLDIDALKVVSKGVNAMRGEGFGAMIITHYQRLLNYITPDVVHV
                     MMEGRVVLSGGPELAARLEREGYAKLAEELGYDYKEEL"
     gene            3517..4779
                     /gene="sufD"
                     /locus_tag="VVR63_000730"
     CDS             3517..4779
                     /gene="sufD"
                     /locus_tag="VVR63_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HEU6128771.1"
                     /translation="MTRENIKLFSEMHAEPSWLADLRQKAFDKIETLELPVIERVKFH
                     RWNLGDGTITENEPSANVPDFTALDHHLKLVQVGTQTVFEQTPVELAEQGVVFTDFHS
                     ALEEIPELIEEFFMSSVKYDDDKLAAYHTAYFNSGAVLYIPDNVEITEPIEGIFYQDS
                     DSNVPFNKHIMIIAGKNSKISYLERLESRGEGSDKATANITVEVIARSGAQVKFAAID
                     RLGENVTAYISRRGKLGNDASIDWAIGVMNEGNVVADFDSDLIGNGSHADLKVVALSS
                     GRQVQGIDTRVTNYGCNSIGNILQHGVILEKATLTFNGIGHIIKGAKGADAQQESRVL
                     MLSDQARSDANPILLIDENDVTAGHAASIGQVDPEDMYYLMSRGLDKATAERLVVRGF
                     LGSVIVEIPVKEVRDEMIATIEEKLSKR"
     gene            4790..6016
                     /locus_tag="VVR63_000731"
     CDS             4790..6016
                     /locus_tag="VVR63_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEU6128772.1"
                     /translation="MLDVEAIRKDFPILDQIVNDEPLVYLDNAATTQKPLVVLKAINS
                     YYEQDNANVHRGVHTLAERATASYEAARETIRKFINAGSTKEVLFTRGTTTSLNWVAR
                     FAEEILTEGDQVLISVMEHHSNIIPWQEACRKTGAELVYVYLKDGALDMEDLRAKLTD
                     KVKFVSLAHASNVLGVVNPIKEITQLAHQVGAIMVVDGAQSTPHMKIDVQDLDLDFFA
                     FSGHKMAGPTGIGVLYGKEKYLEQMSPVEFGGEMIDFVYEQSASWKELPWKFEAGTPN
                     MAGAIGLATAVDYLEKIGMDAVEAHEQELIAYVYPKLQAIEGLTIYGSQDLAQRSGVI
                     AFNLGDLHPHDLATALDYEGVAVRAGHHCAQPLLQYLEVPATARASFYIYNTKADCDK
                     LVDALQKTKEFFNGTF"
     gene            6003..6443
                     /locus_tag="VVR63_000732"
     CDS             6003..6443
                     /locus_tag="VVR63_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HEU6128773.1"
                     /translation="MALSKLDSLYMAVVADHSKNPHHQGKLEDAEQISLNNPTCGDVI
                     NLSVKFDAEDRLEDIAFLNSGCTISTASASMMTDAVLGKTKQEILELATIFSEMVQGQ
                     KDERQDQLGDAAFLSGVAKFPQRIKCATLAWNALKKTIENQEKQ"
     gene            6497..7909
                     /gene="sufB"
                     /locus_tag="VVR63_000733"
     CDS             6497..7909
                     /gene="sufB"
                     /locus_tag="VVR63_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HEU6128774.1"
                     /translation="MAEERVEPKPIDLGEYKFGFHDDVEPVLSTGKGLNEGVIRELSA
                     AKGEPEWMLEFRLKSYETFKKMPMQTWGADLSEIDFDDLIYYQKPSDKPARSWDDVPE
                     KIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKEEFQKLGIIFTDTDSALKEYPD
                     LFNQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNENIGQFE
                     RTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVYNL
                     VTKRAKAQKDATVEWIDGNLGAKTTMKYPSVYLDGEGARGTMLSIAFANAGQHQDTGA
                     KMIHNAPHTSSSIVSKSIAKGGGKVDYRGQVTFNKNSKKSVSHIECDTIIMDDLSASD
                     TIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKELP
                     MEYAVELNRLISYEMEGSVG"
     gene            complement(8140..9381)
                     /locus_tag="VVR63_000734"
     CDS             complement(8140..9381)
                     /locus_tag="VVR63_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEU6128775.1"
                     /translation="MKKIFLTLLTVSLLGGASTAVAQDFTIAAKHAIAVEANTGKILY
                     EKDATQPVEIASITKLITVYLVYEALENGSITLSTPVDISDYPYQLTTNSEASNIPME
                     ARNYTVEELLEATLVSSANSAAIALAEKIAGSEKDFVDMMRAKLLEWGIQDATVVNTT
                     GLNNETLGDNIYPGSKKDEENKLSAYDVAIVARNLIKKYPQVLEITKKPSSTFAGMTI
                     TSTNYMLEGMPAYRGGFDGLKTGTTDKAGESFVGTTVEKGMRVITVVLNADHQDNNPY
                     ARFTATSSLMDYISSTFTLRKIVQQGDAYQDSKAPVQDGKEDTVTAVAPEDIYLIERV
                     GNQSSQSVQFTPDSKAIPAPLEAGTVVGHLTYEDKNLIGQGYITTERPSFEMVADKKI
                     EKAFFLKVWWNQFVRFVNEKL"
     gene            9484..10593
                     /locus_tag="VVR63_000735"
     CDS             9484..10593
                     /locus_tag="VVR63_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEU6128776.1"
                     /translation="MFRRNKLFFWTTEILLLTIIFYLWRQMGSLINPFVSVLNTIMIP
                     FLLGGFLYYLTNPIVTFLNKVCKLNRLLGILITLCTLVWGMVIGVVYLLPILINQLSS
                     LIISSQTIYSRVQDLIIDLSNYPALQNLDVEATIQQLNLSYVDILQNILNSVSNSVGS
                     VLSALISTVLILIMTPVFLVYFLLDGHKFLPMLERTILKRDRLHIAGLLKNLNATIAR
                     YISGVSIDAIIIGCLAYIGYSIIGLKYALVFAIFSGVANLIPYVGPSIGLIPMIIANI
                     FTDPHRLLIAVIYMLVVQQVDGNILYPRIVGSVMKVHPITILVLLLLSSNIYGVVGMI
                     VAVPTYSILKEISKFLSRLYENHKIMKERERELAK"
     gene            11239..11586
                     /gene="ssrA"
                     /locus_tag="VVR63_000736"
     tmRNA           11239..11586
                     /gene="ssrA"
                     /locus_tag="VVR63_000736"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(11768..11855)
                     /locus_tag="VVR63_000737"
     tRNA            complement(11768..11855)
                     /locus_tag="VVR63_000737"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11819..11821),aa:Ser,seq:gga)
     gene            12017..12757
                     /locus_tag="VVR63_000738"
     CDS             12017..12757
                     /locus_tag="VVR63_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEU6128777.1"
                     /translation="MLKTERKQLILEELNQHHVVSLEKLVSLLETSESTVRRDLDELE
                     AENKLRRVHGGAELPHSLQEEETIQEKSVKNLQEKKLLAQKAASLIKEKDVIFIDAGT
                     TTAFLIHELVNKNITVVTNSIHHAAQLVEKQIPTVMVGGNVKTATDASIGGVALNQIN
                     QLHFDRAFIGMNGVDDGYYTTPDMEEGAVKRAILENAKQTYVLVDSSKIGQTCFAKVA
                     PLKRAIVITSQGHELLQVIKEKTEVIEV"
     gene            12754..13665
                     /gene="pfkB"
                     /locus_tag="VVR63_000739"
     CDS             12754..13665
                     /gene="pfkB"
                     /locus_tag="VVR63_000739"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015605104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HEU6128778.1"
                     /translation="MIYTVTLNPSIDYIVRLDQVKVGSVNRMDSDDKFAGGKGINVSR
                     VLKRLNIPNTATGFIGGFTGKFITDTLAEEEIETRFVQVAEDTRINVKIKADQETEIN
                     GTGPTVEPVQLEELKAILSSLTAEDTVVFAGSSAKNLGNVIYKDLISLTRQTGAQVVC
                     DFEGQTLIDSLDYQPLLVKPNNHELGAIFGVKLESLDEIEKYARELLAKGAQNVIISM
                     AGDGALLVTSEGAYFAKPIKGTVKNSVGAGDSMVAGFTGEFVKSKDAVEAFKWGVACG
                     TATTFSDDLATAEFIKETYGKVEVEKR"
     gene            13662..15614
                     /locus_tag="VVR63_000740"
     CDS             13662..15614
                     /locus_tag="VVR63_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU6128779.1"
                     /translation="MKIQDLLRKDVMLLDLQATEKTAVIDEMIKNLTEHSYVTDFETF
                     KEGILAREALTSTGLGDGIAMPHSKNAAVKEATVLFAKSNKGVDYESLDGQATDLFFM
                     IAAPEGANDTHLAALAELSQYLMKDGFADKLRQATSADQVIELFDQASEKTEELVQVP
                     ANDSGDFIVAVTACTTGIAHTYMAQEALQKVAAEMGVGIKVETNGASGVGNQLTAEDI
                     RKAKAIIIAADKAVEMDRFDGKPLINRPVADGIRKTEELINLALSGDTEVYRAANGAK
                     AATASNEKQSLGGAFYKHLMSGVSQMLPFVIGGGIMIALAFLIDGALGVPNENLGNLG
                     SYHELASMFMKIGGAAFGLMLPVFAGYVAYSIAEKPGLVAGFVAGAIAKEGFAFGKIP
                     YAAGGEATSTLAGVSSGFLGALVGGFIAGALVLAIKKYVKVPRSLEGAKSILLLPLLG
                     TILTGFVMLAVNIPMAAINTAMNDFLGGLGGGSAVLLGIVLGGMMAVDMGGPVNKAAY
                     VFGTGTLAATVSSGGSVAMAAVMAGGMVPPLAIFVATLLFKDKFTKEERNSGLTNIIM
                     GLSFITEGAIPFGAADPARAIPSFILGSAVAGGLVGLTGIKLMAPHGGIFVIALTSNA
                     LLYLVSVLVGAIVSGVVYGYLRKPQA"
     gene            15778..18003
                     /locus_tag="VVR63_000741"
     CDS             15778..18003
                     /locus_tag="VVR63_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEU6128780.1"
                     /translation="MLISLGIAILLIFAAFKLGAAGITLYNLIRLLVGSLAYLAIFGL
                     LIYLFFFKWIRKQEGLLSGFFTIFAGLLLIFEAYLVWKYGLDKSVLKGTMAQVVTDLT
                     GFRTTSFAGGGLIGVALYIPTAFLFSNIGTYFIGSILILVGSLLVSPWSVYDIAEFFS
                     RGFAKWWEGHERRKEERFVKQEEKARQKAEKEARLEQEETEKALLDLPPVDMETGEIL
                     TEEAVQNLPPIPEEKWVEPEIILPQAELKFPEQEDDSDDEDVQVDFSAKEALEYKLPS
                     LQLFAPDKPKDQSKEKKIVRENIKILEATFASFGIKVTVERAEIGPSVTKYEVKPAVG
                     VRVNRISNLSDDLALALAAKDVRIEAPIPGKSLIGIEVPNSDIATVSFRELWEQSQTK
                     AENFLEIPLGKAVNGTARAFDLSKMPHLLVAGSTGSGKSVAVNGIIASILMKARPDQV
                     KFMMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFAKVGVRNI
                     AGFNAKVEEFNSQSEYKQIPLPFIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGI
                     HMILATQRPSVDVISGLIKANVPSRVAFAVSSGTDSRTILDENGAEKLLGRGDMLFKP
                     IDENHPVRLQGSFISDDDVERIVNFIKTQADADYDESFDPGEVSENEGEFSDGDAGGD
                     PLFEEAKSLVIETQKASASMIQRRLSVGFNRATRLMEELEMAGVIGPAEGTKPRKVLQ
                     Q"
     gene            complement(18154..18582)
                     /locus_tag="VVR63_000742"
     CDS             complement(18154..18582)
                     /locus_tag="VVR63_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6128781.1"
                     /translation="MSNYRRTSKPKTEHIKKGFTVFQKTITTIGSILGLITAGITIMN
                     ALDNNNKNTKKEPTTSQTTTFVKEIQKESPQENTTPNKENNTSQEKTQQEETPKSSVK
                     EEKKEDQKTATQDSTTPATSKPATENEKQPNTPTSENNTQ"
     gene            18720..19862
                     /locus_tag="VVR63_000743"
     CDS             18720..19862
                     /locus_tag="VVR63_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEU6128782.1"
                     /translation="MIYFDNSATTRPYPEALETYMQVASKILGNPSSLHRLGDQATRI
                     LDASRQQIADLIGKKSDEIFFTSGGTEGDNWIIKGVAFEKAQFGKHIIVSAIEHPAVK
                     ESALWLKAQGFEVDFAPVDNKGFVDVEALEDLIRPDTTLVSIMAVNNEIGSIQPIEAI
                     SEFLADKPTISFHVDAVQALAKIPTEKYLTERVDFATFSGHKFHGIRGVGFIYIKSGK
                     KITPLLTGGGQERDYRSTTENVAGIAATAKALRLSMEKLDIFRSKTGQMKAVIRQALL
                     DYPDIFVFSDEEDFAPHILTFGIKGVRGEVIVHAFEDYDIFISTTSACSSKAGKPAGT
                     LIAMGVDKDKAQSAVRLSLDLENDMSQVEQFLTKLKLIYNQTRKVR"
     gene            19871..21085
                     /gene="thiI"
                     /locus_tag="VVR63_000744"
     CDS             19871..21085
                     /gene="thiI"
                     /locus_tag="VVR63_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HEU6128783.1"
                     /translation="MQYSEIMIRYGELSTKGKNRMRFINKLRNNISDVLSIYPQVKVT
                     ADRDRAHAYLNGADYTAVAESLKQVFGIQNFSPVYKVEKSVEVLKSAVQEIMQDIYKE
                     GMTFKISSKRSDHTFELDSRELNQTLGGAVFEAIPNVQAQMKSPDINLQVEIREEAAY
                     LSYETVRGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGVDIEAVHFASPPYTSPG
                     ALKKAQDLTRKLTKFGGNIQFIEVPFTEIQEEIKAKAPEAYLMTLTRRFMMRITDRIR
                     EVRNGLVIINGESLGQVASQTLESMKAINAVTNTPIIRPVVTMDKLEIIDIAQEIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKIKNAEQYEARMDVEGLVERAVAGIMITEITPQAE
                     KDEVDDLIDNLL"
     gene            21220..22044
                     /locus_tag="VVR63_000745"
     CDS             21220..22044
                     /locus_tag="VVR63_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HEU6128784.1"
                     /translation="MNQSYFYLKMKEHKLKVPYTGKERRVRILLPKDYEKDTDRSYPV
                     VYFHDGQNVFNSKESFIGHSWKIIPAIKRNPDISRMIVVAIDNDGMGRMNEYAAWKFQ
                     ESPIPEQQFGGKGVEYAEFVMEVVKPFIKHKTGWFDGMMTTGCSMGAYHALNFFLQHP
                     DVFTKVIALSGVYDARFFVGDYYNDDAIYQNSPVDYIWNQNDGWFIDRYRQAEIVLCT
                     GLGAWEQDGLPSFYKLKEAFDKKQIPAWFAEWGHDVAHDWEWWRKQMPYFLGNLYL"
     gene            22057..23223
                     /locus_tag="VVR63_000746"
     CDS             22057..23223
                     /locus_tag="VVR63_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEU6128785.1"
                     /translation="MNYLVISPYYPQNFQQFTIELANKGITVLGIGQESYEQLDEPLR
                     NSLTEYFRVDNLENIDEVKRAVAFLFYKHGPIGRIESHNEYWLELDATLREQFNVFGA
                     KPEDLKKTKYKSEMKKLFKKAGVPVVPGAVIKTEADVDQAVKEIGLPMIAKPDNGVGA
                     AATFKLETEDDINHFKQEWDHSTLYFFEKFVTSSEICTFDGLVDKDGKIVFSTTFDYA
                     YTPLDLMIYKMDNSYYVLKDMDPKLRKYGEAIVKEFGMKERFFHIEFFREGDDYITIE
                     YNNRPAGGFTIDVYNFAHSLDLYRGYAAIVAGEEFPASDFETQYCLATSRRANAHYVY
                     SEEDLLAKYSQQFKVKKVMPAAFAELQGDYLYMLTTPSRQEMEQMIADFGQRQE"
     gene            23731..25224
                     /locus_tag="VVR63_000747"
     CDS             23731..25224
                     /locus_tag="VVR63_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEU6128786.1"
                     /translation="MITGELKNKIDQLWEILWTEGNANPLTNIEQLTYLLFMKDLDSV
                     ELGRESDAEFLGIPYEGVFPKDKPEYRWSTFKNIGDAQEVYRLMTQEIFPFIKNLKGD
                     TDDTAFSRYMREAIFQINKPATLQKAISILDVFPTRGLDVDFDNDKQSITDIGDIYEY
                     LLSKLSTAGKNGQFRTPRHIIDMMVELMQPTIKDIISDPAMGSAGFLVSASRYLKRKK
                     DEWETNTDNINHFHNQMFHGNDTDTTMLRLGAMNMMLHGVENPQISYLDSLSQDNEEA
                     DKYTLVLANPPFKGSLDYNSTSNDLLATVKTKKTELLFLSLFLRTLKPGGRAAVIVPD
                     GVLFGSSKAHKGIRQEIVENHKLDAVISMPSGVFKPYAGVSTAILIFTKTGNGGTDKV
                     WFYDMKADGLSLDDKRQPISDNDIPDIIERFHHLEKEAERQRTDQSFFVPVAEIKEND
                     YDLSINKYKEIEYEKVEYEPTEVILKKINDLEKEIQAGLAELEKLLK"
     gene            25237..25779
                     /locus_tag="VVR63_000748"
     CDS             25237..25779
                     /locus_tag="VVR63_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU6128787.1"
                     /translation="MKKVKLGEVLSLKKGKKATVLAEQTTLSQRYIQIDDLRNNNNLK
                     FTESLNMTEALPDDILIAWDGANAGTVGYGLSGAVGSTITVLKKNERYKEKIISDYLG
                     VFLESKSQYLREHSTGATIPHLNKNILLDLQLELLGIEEQENIICILNTIKRLITKRK
                     LQLDELNLLVKSRYSEEVVA"
     gene            25776..26894
                     /locus_tag="VVR63_000749"
     CDS             25776..26894
                     /locus_tag="VVR63_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU6128788.1"
                     /translation="MKKVKLGEVATFINGYAFKPQDWSSEGKEIIRIQNLTKTSTEIN
                     YYSGTIDKKYIVEAGDILISWSGTLGVFQWRGRSAVLNQHIFKVVFDKIDIDKSYFKY
                     VVEKGLQDAVKHTHGSTMKHLTKKYFDNIIVPYTNLGEQQRIASELDLLSKLILRRQE
                     QLEELNLLVKSRFNEMFGENKIFESIDNLFDIIDGDRGKNYPKSDELFSEEYCLFLNT
                     KNVTKNGFSFDTKQFITKTKDKLLRKGKLERYDIVLTTRGTVGNVAYYDELIKYKHLR
                     INSGMVILRPKTPNLNQKFIIHVLRNNNYSRVISGSAQPQLPITKLKKILLPLPPLAL
                     QNEFADFVALVDKSQLAIQKSLEELETLKKSLMQEYFG"
     gene            26954..27190
                     /locus_tag="VVR63_000750"
     CDS             26954..27190
                     /locus_tag="VVR63_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HEU6128789.1"
                     /translation="MVVKTRKQGNSITITIPSEFNIPSGVKYEAKLLPSGEIIFTPEE
                     LGQQVSYVSDDAFDLNLDKIFDEYDDVFKALVEK"
     gene            27187..27600
                     /locus_tag="VVR63_000751"
     CDS             27187..27600
                     /locus_tag="VVR63_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000158364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HEU6128790.1"
                     /translation="MTIYLTEKQIEKINALAIQRYSPNEKIQTVSSSALNMIVNLPEQ
                     FVFGKSLYPTIFDKATILFVQLIKKHVFANANKRTAFFVLVKFLQLNGYRFSVTVEEA
                     VKMCVTIAVEALTDEKMTSYSKWVSEHSVREKVKK"
     gene            27718..28683
                     /locus_tag="VVR63_000752"
     CDS             27718..28683
                     /locus_tag="VVR63_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEU6128791.1"
                     /translation="MESKVTIIMQEMLPLLNNEQLLALRESLEHHLVDGKKQQKYSNN
                     NLLQLFITAKQVEGCSSKTIRYYQRTIENLFNAIKESVTQLTTDDLRSYLANYQSEKD
                     CSKANLDNIRRILSSFFAWLEQEEYIIKNPIRRIKKIKTEQNVKETYTDEHLEIMRDN
                     CENLRDLAIIDLLASTGMRVGELVQLNRSDIDFENRECVVFGKGKKERPVYFDARTKI
                     HLRNYLNDRKDSHPALFVTLVGKAQRLGIAGVEIRLRKLGDKLGIQKVHPHKFRRTLA
                     TKAIDKGMPIEQVQKLLGHSKIDTTLAYAMVNQNNVKHSHQKFIS"
     gene            28649..29230
                     /locus_tag="VVR63_000753"
     CDS             28649..29230
                     /locus_tag="VVR63_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU6128792.1"
                     /translation="MSSIHTKNSSLKSKSRFNEMFGDPLNNNKKFAVKTGQQCFKFSS
                     GKFLDKHDRVFEGYPAYGGNGIAWKSRKYLIDNPTIIIGRVGAYCGNVRTTHGKVWIS
                     DNAIYIKEFKNSDFNLVFLLELMKVIDFSKFADFSGQPKITQKPLENQKYILPPLALQ
                     NEFADFVAQVDKSQFACEIAIKVWRNSLKFSII"
     gene            29260..32610
                     /locus_tag="VVR63_000754"
     CDS             29260..32610
                     /locus_tag="VVR63_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEU6128793.1"
                     /translation="MGNFSFLLKNDEYESFSKPCIEAENMIATSTVATAFMARRALEQ
                     AVHWIYSHDSYLEAPYRATLSSLVWDDDFRDIVDSELHKQIVLLIRWGNHAAHGGEIK
                     EREAILALHHLYQFVNFIDYCYSNEFVERYFDEKCLPLSANIKYRETPQSMINLQDSL
                     PELPDFHEQMAAQSVEVQETYTEKRETAAQRQDVPFHIDQLSEAETRKLFIDIDLRLA
                     GWIFEENCRVEIAVDGLKHGSGIGYCDYVLYGKNGKILAIVEAKKASVNPEVGEVQVK
                     EYAEALEKHIGYQPICFITNGLKHYILDGPNRRQIAGFYSQEELQLVMDRRHLQKPLE
                     DISSKIRDDISGRHYQKHAIASVCEAFSNHRRQALLVMATGAGKTRTAVSLVDILSRH
                     NWVKNVLFLADRTSLVKQAYDSFRKLLPDLSVCNFLEDKEGAQSSRMVFSTYPTMIGA
                     ISGQEEVNQRPFTVGHFDLIIIDESHRSIYQKYKSIFDYFDARIVGLTATPRQDLDKN
                     TYGFFNLENGVPTYAYDLEEAVKDGYLVAYHSIETKLKLPTDGLHYDDLSEEEKEHFD
                     SKFEDNSCEKDIDGSVFNSFIFNKSTVEIVLNELMTRGIQTASGDEIGKTIIFAKNHD
                     HAEYIRGIFNNRYPEKGSDYAQVIDYSIKHYQTLIDDFKIKEKYPQIAISVDMLDTGI
                     DVPEVVNLVFFKKVRSKTKFWQMIGRGTRLCKDLFGPEQDKENFLVFDYGDNFDYFRA
                     DPRDGEGRHIVSLTQRLFNIKVDLIRELQGLQYQEDQFARAYRQQLVSELQGRIESLN
                     ELDFRVRMVLDTVYSYRKLESWQNLTAVTSETIQKNLSPLLFDEDKEDEMARRFDLWL
                     LHIQLGQLTAKSSTVHISQVMKTARALSAIGNIPQVFEQAEIIRKVQEPEFWKEVNLS
                     DLEKIRLAIRDLLQFLDKTDRKPYYVNFEDRILSTVHETTAFLQVNDLRSYNEKVEHY
                     LKTHLDEESISKLYHNKKLTSDDMLALEKLLWEKLGSKADYQSHYENKAIPRLVREII
                     GLDRESANRIFSKFLSDENLNARQISFVKLIVDYIVENGFLETKVLTQEPFKSYGSVQ
                     LLFQHQLPVLRNIVQIIELINNRAGEAA"
     gene            complement(33116..33586)
                     /locus_tag="VVR63_000755"
     CDS             complement(33116..33586)
                     /locus_tag="VVR63_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEU6128794.1"
                     /translation="MNKSEHRHQLIRALITKNKIHTQAELQALLAENDIQVTQATLSR
                     DIKNMNLSKVREEDSAYYVLNNGSISKWEKRLELYMEDALVWMRPVQHQVLLKTLPGL
                     AQSFGSIIDTLSFPDAIATLCGNDVCLIICEDADTAQKCFEELKKFAPPFFFEE"
     gene            complement(33603..35876)
                     /locus_tag="VVR63_000756"
     CDS             complement(33603..35876)
                     /locus_tag="VVR63_000756"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HEU6128795.1"
                     /translation="MRFNQYSYINFPKENVLSELKKCGFDLQNTANHKDSLETFLRRF
                     FFTYQDTNYPLSILAADKKTDLLTFFQSEDELTADIFYTVAFQLLGFSYLVDFEDSDV
                     FRKETGFPIIYGDLIENLYQLLNTRTKKGNTLIDQLVSDGLIPEDNDYHYFNGKSLAT
                     FSNQDVIREVVYVESRVDTDQKGLSDLVKVSIIRPRFDGKIPAIMTASPYHQGTNDKA
                     SDKALYKMEGELEVKLPHKIELEKPQLNLVQPQGKAELIAEAEEKLTHINSSYTLNDY
                     FLPRGFANLYVSGVGTKDSTGFMTNGDYQQIEAYKNVIDWLNGRCRAFTDHTRQRQVK
                     ADWSNGKVATTGLSYLGTMSNGLATTGVDGLEVIIAEAGISSWYNYYRENGLVTSPGG
                     YPGEDFDSLAELTYSRNLLAGDYIRGNEAHQADLEKVKAQLDRKTGDYNQFWHDRNYL
                     LNAHKVKAEVVFTHGSQDWNVKPLHVYQMFHALPTHIHKHLFFHNGAHVYMNNWQSID
                     FRESINALLTKKLLGQETDFQLPTVIWQDNTAPQTWLSLDNFGGQENCETFSLGQEEQ
                     AIQNQYPDKDFERYGKTYQTFNTELYQGKANQITINLPVTKDLHLNGRAQLNLRIKSS
                     TNKGLLSAQLLEFGQKKYLQPYPAILSARTIDNGRYHMLENLCELPFRPEAQRVVTKG
                     YLNLQNRNDLLLVEDITADEWMDVQFELQPTIYKLKEGDTLRLVLYTTDFEITIRDNT
                     DYHLTVDLAQSMLTLPC"
     gene            36223..39324
                     /locus_tag="VVR63_000757"
     CDS             36223..39324
                     /locus_tag="VVR63_000757"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000561528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HEU6128796.1"
                     /translation="MIAQLDTKTVYSFMESVISIEKYVRAAKEYGYTHLAMMDIDNLY
                     GAFDFLDITKKYGIHPLLGLEMTVFVDDQEVNLRFLALSSVGYQQLMKLSTAKMQGEK
                     TWSVLSQYLEDIAVIVPYFDRVELLELGCDYYIGVYPETLASEFHHPILPLYRVNAFE
                     SRDREVLQVLTAIKENLPLREVPLRSRQDVFISASSLEKLFQECFPQALDNLEKLISG
                     ISYDLDTSLKLPRFNPARPAVEELRERAELGLVQKGLTSKEYQDRLDQELSVIHDMGF
                     DDYFLVVWDLLRFGRSNGYYMGMGRGSAVGSLVSYALDITGIDPVEKNLIFERFLNRE
                     RYTMPDIDIDIPDIYRPDFIRYVGNKYGSKHAAQIVTFSTFGAKQALRDVLKRFGVPE
                     YELSAITKKISFRDNLKSAYEGNLQFRQQINSKLEYQKAFEIACKIEGYPRQTSVHAA
                     GVVISDQDLTNYIPLKYGDEIPLTQYDAHGVEASGLLKMDFLGLRNLTFVQKMQELLA
                     ETEGIHLKIEEIDLEDKETLALFASGNTKGIFQFEQPGAIRLLKRVQPVCFEDVVATT
                     SLNRPGASDYINNFVARKHGQEEVTVLDPVLEDILAPTYGIMLYQEQVMQVAQRFAGF
                     SLGKADILRRAMGKKDASAMHEMRASFIQGSLEAGHTVEKAEQVFDVMEKFAGYGFNR
                     SHAYAYSALAFQLAYFKTHYPAIFYQIMLNSANSDYLIDALEAGFEVAPLSINTIPYH
                     DKIANKAIYLGLKSIKGVSNDLALWIIENRPYSNIEDFIAKLPENYLKLPLLEPLVKV
                     GLFDSFEKNRQKVFNNLANLFEFVKELGSLFGDAIYSWQESEDWTEQEKFYMEQELLG
                     IGVSKHPLQAIASKAIYPITPIGNLSENSYAIILVEVQKIKVIRTKKGENMAFLQADD
                     SKKKLDVTLFSDLYRQVGQEIKEGAFYYVKGKIQSRDGRLQMIAQEIREAVAERFWIQ
                     VKNHESDQEISRILEQFKGPIPVIIRYEEEQKTIVSPHHFVAKSNELEEKLNEIVMKT
                     IYR"
     gene            39407..40414
                     /gene="pfkA"
                     /locus_tag="VVR63_000758"
     CDS             39407..40414
                     /gene="pfkA"
                     /locus_tag="VVR63_000758"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HEU6128797.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRQAISEGMEVFGIYDGYAGM
                     VAGEIHPLDAASVGDIISRGGTFLHSARYPEFAQLEGQLKGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAIGLPGTIDNDIVGTDFTIGFDTAVTTAMDAIDKIRDTSSSH
                     RRTFVIEVMGRNAGDIALWAGIATGADEIIIPEAGFKMEDIVASIKAGYECGKKHNII
                     VLAEGVMSAAEFGQKLKEAGDTSDLRVTELGHIQRGGSPTARDRVLASRMGAHAVKLL
                     KEGIGGVAVGIRNEKMVENPILGTAEEGALFSLTAEGKIVVNNPHKADIELSSLNKSL
                     S"
     gene            40473..41978
                     /gene="pyk"
                     /locus_tag="VVR63_000759"
     CDS             40473..41978
                     /gene="pyk"
                     /locus_tag="VVR63_000759"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HEU6128798.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDVEASAKNIAK
                     LIEAGANTFRFNFSHGDHQEQGERMATVKLAEKIAGKKVGFLLDTKGPEIRTELFEGE
                     AKEYSYKTGEKIRVATKQGIKSTREVIALNVAGALDIYDDVEVGRQVLVDDGKLGLRV
                     VAKDDATREFEVEVENDGIIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIA
                     ISFVRTAKDVNEVRAICEETGNGHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVYQKMIIKKVNAAGKVVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPLESVTTMATIDKNAQALLNEYGRLDSDSFERNSKTEVMASAVK
                     DATSSMDIKLVVTLTKTGHTARLISKYRPNADILALTFDELTERGLMLNWGVIPMLTD
                     APSSTDDMFEIAERKAVEAGLVESGDDIVIVAGVPVGEAVRTNTMRIRTVR"
     gene            complement(42729..42954)
                     /locus_tag="VVR63_000760"
                     /pseudo
     CDS             complement(42729..42954)
                     /locus_tag="VVR63_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838792.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            43802..44674
                     /locus_tag="VVR63_000761"
     CDS             43802..44674
                     /locus_tag="VVR63_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HEU6128799.1"
                     /translation="MKKSRKLATLGICSALFLGLAACQQQHATSEGTNQRQSSSAKVP
                     WKASYTNLNNQVSTEEVKSLLSAHLDPNSVDAFFNLVNDYNTIVGSTGLSGDFTSFTH
                     TEYDVEKISHLWNQKKGDFVGTNCRINSYCLLKNSVTIPKLEKNDQLLFLDNDAIDKG
                     KVFNSQDKEEFDILFSRVPTEATTDVKVHAEKMETFFSQFQFNEKARMLSVVLHDNLD
                     GEYLFVGHVGVLVPADDGFLFVEKLTFEEPYQAIKFASKEDCYKYLGTKYADYTGEGL
                     AKPFIMDNDKWVKL"
     gene            44687..44851
                     /locus_tag="VVR63_000762"
     CDS             44687..44851
                     /locus_tag="VVR63_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001836122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6128800.1"
                     /translation="MTVILGFLFLFLMTWWVISIVNSQKPLKNETFIGYVQRYDIDGN
                     GYQSLPCPQN"
     gene            complement(44820..44900)
                     /locus_tag="VVR63_000763"
                     /pseudo
     CDS             complement(44820..44900)
                     /locus_tag="VVR63_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
BASE COUNT        13767 a         7924 c         9666 g        13543 t
ORIGIN      
        1 atatgattct ttctaatgag ttgttttgtt gcttttcatt ataggtcata tgggactttt
       61 tttctacaca aaataggctc cataatatcc ataggggatt tacccactac aaatattata
      121 gagcccaaaa tcctttgttt actaaacaag ggatttttct tttgtctctg ctcctttttt
      181 gatataatag ttctatgtta aaatcagaaa aacaatcacg ttatcaaatg ttaaatgaag
      241 aattgtcctt cctattggaa ggcgaaacca atgttttggc taatctttcc aacgccagtg
      301 ctctcataaa atcacgtttt cctaataccg tatttgcagg cttttatttg ttcgatggaa
      361 aggaattggt tttaggcccc ttccaaggag gtgtttcctg catccgtatt gcactaggca
      421 agggtgtttg tggtgaggca gctcactttc aggaaactgt tattgttgga gatgtgacga
      481 cctatctcaa ctatatttct tgtgatagtc tagctaaaag tgaaattgtg gtgccgatga
      541 tgaagaatgg tcagttactt ggagttctgg atctggattc ttcagagatt gaggattacg
      601 atgctatgga tcgagattat ttggaacaat ttgtcgctat tttgcttgaa aagacaacat
      661 gggactttac gatgtttgag gaaaaatctt aatgtatcaa gcactttatc gaaaatatag
      721 aagtcaaaac ttctcccagt tagttggtca agaagttgtg gctaagactc ttaaacaagc
      781 ggtggagcaa gagaaaataa gtcacgctta tcttttttct ggtcctcgtg gaacgggaaa
      841 aaccagtgtt gctaaaatct ttgccaaggc tatgaactgt cccaatcaag tgggtggcga
      901 accttgcaat aactgctata tttgtcaagc agtgacggac ggtagtttag aagatgtcat
      961 tgaaatggat gcagcttcta ataatggggt agatgaaatt cgcgaaattc gtgataaatc
     1021 tacctatgcg cctagccttg ctcgttataa ggtttatatc atagatgagg ttcacatgct
     1081 gtctacaggg gcttttaatg ccctcctaaa gacgctggaa gaaccaacac agaatgtagt
     1141 ctttattttg gccactactg aattgcacaa gattcctgct actattctat cccgtgtgca
     1201 acgttttgag tttaaatcaa ttaagacaca ggatattaag gaacatattc actatatctt
     1261 agaaaaagaa aatatcagtt ctgaaccaga ggctgtggaa atcattgcca ggcgggcgga
     1321 aggtggaatg cgggacgcct tgtctatttt ggatcaagcc ctgagtttga cacagggaaa
     1381 tgagctgacg actgctatct ctgaagaaat tactggcacc attagcctat cagccttgga
     1441 tgattatgtg gcggccttgt ctcaacagga tgttcccaaa gctttgtctt gcttgaatct
     1501 tctttttgac aatggtaaga gcatgactcg ttttgtgacc gatcttttgc actatttaag
     1561 agacttgtta attgttcaaa cagggggaga aaatactcat catagttcag tctttgtaga
     1621 aaatttggca cttcctcaaa aaaatctgtt tgaaatgatt cgcttagcaa cagtgagttt
     1681 agcagatatt aagtctagtt tgcagcccaa gatttatgct gaaatgatga ccgtccgttt
     1741 ggcggaaatc aagcccgaac cagctctatc aggagcggtt gaaaatgaaa ttgctacgct
     1801 gagacaggaa gttgcccgtc tcaaacaaga gctttctaat gtaggtgcgg ttcctaaaca
     1861 agttgcacca gctcctagtc gaccagctac gggcaaaaca gtctatcgtg tcgatcgcaa
     1921 taaagtgcaa tctatcttac aagaggccgt cgaaaatcct gatttagcac gtcaaaatct
     1981 aattcgtttg cagaatgcct ggggagaggt aattgaaagt ctaggtgggc cggacaaggc
     2041 tctgctagtt ggttctcaac cggttgctgc caatgaacac catgctattc ttgcttttga
     2101 gtctaacttc aatgctggtc aaactatgaa acgagacaat ctcaatacca tgtttggtaa
     2161 tatcctcagt caggcggcag gtttttcacc tgagatttta gctatttcca tggaggaatg
     2221 gaaagaagtt cgcgcagcct tttcagccaa agccaaatct tctcaaactg aaaaagaagt
     2281 agaagaaagc ctgattccag aaggatttga atttttggct gataaagtga aggtagagga
     2341 agactaaaga aagatttcat gatacaataa gtttatgaat aaacaacaat ttattattat
     2401 ggcgctgttt acagctgctg agacctattt tttcaatgaa gcctggatga ctggccgcta
     2461 tattatggca gccttttggg caattttact ctttagaaat ttccgagtca gttatgtgat
     2521 gggcaaaatc gttgatgtca tcgatcagca ttttaatagg aaagactagc cctcagcttc
     2581 cagacaaaat caaagccttt taggcttttt tttgttatac tagaaaagta tatttataga
     2641 atttttgctc tatttctggg gaaatcagac gtttttctag taagtactgt aaaagttttg
     2701 aaaaagaaag gaactatcat gtcagtatta gagattaaag atcttcacgt tgagattgaa
     2761 ggaaaagaaa ttttaaaagg ggttaacctg accctgaaaa caggagaaat tgccgctatc
     2821 atgggaccaa atggtacagg taaatcgact ctttctgccg ctatcatggg aaatccaaac
     2881 tatgaagtaa ctaaaggtga agttttgttt gatggcgtaa acatccttga gttggaagtg
     2941 gatgagcgtg cgcgtatggg acttttcctt gctatgcaat acccatcaga aatccctgga
     3001 attaccaatg ctgagtttct tcgtgccgct atgaatgcgg gtaaagaagg tgatgagaag
     3061 atttcagttc gtgagtttat tactaagcta gatgaaaaaa tggaattgct caacatgaaa
     3121 gaagaaatgg cagagcgtta cctcaacgaa ggcttctctg gtggtgagaa aaaacgcaat
     3181 gaaattcttc aacttttgat gttggagcca acatttgctc ttttggacga gattgactca
     3241 ggtcttgata ttgacgctct taaagttgtg tctaaaggtg tcaatgccat gcgtggtgaa
     3301 ggttttggtg ctatgatcat cactcactac caacgtcttt tgaactatat cacacctgat
     3361 gtggtacacg tgatgatgga aggtcgtgtt gtcctttctg gtggtccaga attggctgcg
     3421 cgtttggaac gtgaaggata cgcaaaatta gctgaagaac ttggctacga ctacaaggaa
     3481 gaattgtaat ttcctcgtat cttttaggag aagtaaatga ctagagaaaa tattaaactt
     3541 ttttcagaaa tgcacgctga accaagctgg ttggctgatc tccgtcaaaa agcttttgac
     3601 aagattgaga ctttggaatt accagttatt gagcgtgtca aattccaccg ttggaatctg
     3661 ggtgatggaa cgattacaga aaatgagcca tcagcaaatg ttccagattt cacagcttta
     3721 gatcatcact tgaagttggt gcaagtagga actcaaactg ttttcgaaca aactccagtt
     3781 gagttagctg aacagggtgt tgtcttcaca gactttcact cagctttaga agaaattcca
     3841 gagctgatcg aagaattctt catgtcatct gttaagtatg atgatgacaa gttggcggct
     3901 taccacacag cttactttaa cagtggtgct gtactctata ttccagataa cgtagaaatc
     3961 acagagccaa ttgaaggaat tttctaccaa gatagcgata gcaatgtgcc gtttaacaag
     4021 catattatga ttatcgctgg taaaaattct aagattagtt atctggagcg tttagagtca
     4081 cgcggtgaag gaagtgacaa agcaactgcc aatatcacag tggaagtgat tgcacgttct
     4141 ggtgcgcaag tcaagtttgc tgctattgac cgtctaggtg aaaacgtcac tgcctacatt
     4201 agccgtcgtg gtaaattagg caacgatgca agtattgact gggctatcgg tgtcatgaac
     4261 gaaggaaatg tcgttgctga ttttgatagt gacttgattg gtaatggtag ccatgctgac
     4321 ctcaaggttg tagctctttc aagtggtcgt caggtacaag ggattgatac tcgtgtaact
     4381 aactatggct gcaactctat cggaaatatc ctacaacatg gggttatcct tgaaaaagca
     4441 actttgactt tcaatggtat cggccacatc atcaagggtg ctaagggagc agatgcccaa
     4501 caagagagcc gtgttctcat gctttcagac caagcgcgtt cagatgctaa cccaattctt
     4561 ttgattgatg aaaatgacgt cactgcagga catgcagcct ctattggtca ggtagatcca
     4621 gaagatatgt actacctcat gagtcgtgga ttggataagg caactgcaga gcgtttggtt
     4681 gttcgtggtt tccttggatc tgttatcgtg gagattccag tcaaggaagt tcgtgatgaa
     4741 atgattgcaa ctatcgaaga gaaattgtca aaacgctaag gggaagccta tgttagatgt
     4801 agaagcgatt cgcaaggatt ttccaatttt agatcagatt gtcaatgatg aacctctggt
     4861 ctatctggac aatgctgcga cgacacaaaa accactagta gttctgaaag ctattaacag
     4921 ttactatgag caggacaatg ccaatgttca ccgtggtgtc cataccttag cggaacgagc
     4981 gacagcttct tatgaagctg ctcgtgaaac cattcgtaag tttattaatg caggctctac
     5041 aaaggaagtt ctctttacca gaggaacgac aaccagcctt aactgggtgg cacgctttgc
     5101 tgaggaaatt ctcactgagg gagaccaggt cttgatttca gtaatggaac accattctaa
     5161 tatcattcca tggcaggaag cttgtcgaaa gactggagca gagcttgtct atgtctatct
     5221 taaagacggt gccttggata tggaggattt gcgagctaaa ttgactgata aggttaaatt
     5281 tgtttcccta gctcatgcct ccaatgttct tggtgtggtc aatccgatca aggaaatcac
     5341 tcaattagcc caccaagttg gggcaatcat ggtagtggat ggtgctcaat ctacacctca
     5401 tatgaagatt gatgtccagg acttggatct ggactttttc gccttttcgg gtcacaagat
     5461 ggctggtccg actggtatcg gtgtccttta cggcaaagaa aagtatcttg agcaaatgtc
     5521 tccagtagaa tttggcggcg agatgattga ttttgtctac gagcaatctg ctagttggaa
     5581 ggaattgcct tggaaatttg aggctggaac gccaaatatg gcaggagcta ttggacttgc
     5641 gactgcagtt gattatctgg aaaagattgg tatggatgcc gttgaagctc atgaacagga
     5701 attgattgcg tacgtctatc caaaactgca ggcaattgag ggattgacca tttacggttc
     5761 tcaggatttg gctcaacgtt cgggtgttat tgcctttaac ctaggtgatc tccatcctca
     5821 cgatcttgcg acagctctgg attatgaagg agtggctgtt cgtgctggtc accattgtgc
     5881 gcaacccttg cttcagtatt tggaagtccc agcaacagct cgtgcaagtt tttatatcta
     5941 taataccaag gcagattgcg acaaactagt cgatgcccta caaaagacaa aggagttttt
     6001 caatggcact ttctaaacta gatagccttt atatggcagt ggtagcagac cattcgaaaa
     6061 atccacatca ccaagggaag ttagaagacg ctgagcaaat cagtctcaac aatccgactt
     6121 gtggagatgt catcaatctc tctgtcaagt ttgatgcaga ggaccgtttg gaagatattg
     6181 cttttctaaa ttcaggatgc acgatttcaa ctgcttctgc tagtatgatg acagatgccg
     6241 ttttaggaaa aaccaaacaa gaaattttag aactggcgac tattttttct gaaatggttc
     6301 aagggcaaaa agatgagcgt caagaccaac ttggagacgc ggcattcttg tcaggtgttg
     6361 ccaaattccc tcaaagaatc aagtgtgcaa ccctagcttg gaatgccctt aagaaaacaa
     6421 ttgaaaatca agaaaaacag taagacaagt ttcttttgtc ttatgaatta ttagaaatga
     6481 agaaagaaag gatattatgg ctgaagaaag agtagaacca aaaccaattg accttggtga
     6541 atataaattt ggtttccatg acgatgtaga gcctgtctta tcgacaggaa aaggactcaa
     6601 cgaaggtgtt attcgtgaat tatctgctgc taagggtgag cctgagtgga tgttggagtt
     6661 ccgtttgaag tcttatgaaa ccttcaaaaa aatgcccatg caaacttggg gagcagactt
     6721 gtcagagatt gactttgatg acttaatcta ctaccaaaaa ccatctgaca aaccagcccg
     6781 ttcttgggat gatgtacctg aaaagattaa agaaaccttt gaacgtatcg ggattccaga
     6841 agctgaacgt gcttatttag caggggcttc tgcccagtac gagtcagaag tggtttacca
     6901 caacatgaag gaagagttcc aaaaattagg tattatcttt acagatacag attccgcact
     6961 caaggaatac ccagacttat ttaatcaata ctttgcgaag ttggtaccgc cgacagataa
     7021 caagttggca gccctcaact cagcagtatg gtcgggtgga acttttatct acgtgccaaa
     7081 aggtgtcaag gtagatattc cacttcaaac ttatttccgt atcaataacg aaaatatagg
     7141 tcagttcgaa cgtaccttga ttatcgttga tgagggagca agcgtccact acgtagaagg
     7201 atgtacagca ccaacatatt caagcaatag cttacacgct gccattgtag aaatttttgc
     7261 tttggacgga gcttatatgc gttatacaac tatccaaaac tggtctgata acgtctataa
     7321 cttggtaaca aagcgtgcta aggctcaaaa ggatgccact gttgagtgga ttgatggaaa
     7381 cttgggtgcc aaaacgacta tgaaatatcc atctgtttac cttgatggag aaggagcgcg
     7441 tggtaccatg ctctctatcg cctttgctaa tgcagggcaa caccaagaca cgggtgctaa
     7501 gatgattcac aatgctccac ataccagctc gtctattgtg tctaaatcca tcgctaaagg
     7561 tggaggaaag gttgactacc gtggacaagt cacctttaac aagaactcta agaaatctgt
     7621 ttcccacatt gaatgtgata ccattatcat ggatgacttg tcagcatcag atactattcc
     7681 atttaatgaa attcacaact cgcaagtggc tttggaacac gaagccaaag tatctaagat
     7741 ttcagaagag caattgtatt atctcatgag ccgtggattg tcagaatctg aggcaactga
     7801 aatgattgtc atgggatttg tagaaccctt tacaaaagaa cttccaatgg aatacgcagt
     7861 tgagctgaac cgcttgatta gctatgaaat ggagggatca gttggataaa atttgatttt
     7921 atactcttcg aaaatctctt caaaccacgt cagcatcgcc ttaccgtatg tatggttact
     7981 gacttcgtca gtttcatcta caacctcaaa acagtgtttt gagcaacctg cggctagctt
     8041 cctagtttat tctttgattt tgagtattag atttactcaa aatcaaggat tttgaagatg
     8101 aacttgtatc aaaaaatcgc ggtttaaaat cgcgattttt tataatttct cgttaacaaa
     8161 gcggacaaac tgattccacc aaacttttaa gaagaaggct ttttcaattt tcttgtctgc
     8221 taccatttcg aaactagggc gctctgtggt gatgtaacct tgaccaatca agttcttgtc
     8281 ttcataagtc aaatggccaa ccactgttcc agcttcaagt ggtgctggga ttgctttgga
     8341 atcaggtgtg aattgaacag attgggaaga ttgattccca acacgttcta ttagatagat
     8401 atcctctgga gccactgcag ttactgtatc ttcttttcca tcttgtacag gggctttgct
     8461 atcttgatag gcatcgcctt gttgaacgat tttgcgaagt gtaaatgtag aagaaatata
     8521 atccattagg gaagatgtag ctgtaaatcg agcgtaagga ttattgtctt gatgatctgc
     8581 atttaaaaca actgtgatga ctctcatgcc tttttcgaca gtagtaccaa caaaagactc
     8641 tccagcctta tctgttgttc ctgtttttag cccatcaaaa ccaccacggt aagcaggcat
     8701 accttctaac atgtagttgg ttgaagtgat tgtcatccca gcaaaagtag aagaaggttt
     8761 tttggtgatt tctaagactt gtgggtattt tttgatgagg ttgcgagcaa cgatagcgac
     8821 atcataagca ctaagcttat tttcctcatc ttttttagaa cctgggtaaa tgttatcccc
     8881 tagagtttca ttgttaagac ctgtcgtatt gacaacagtg gcatcctgaa ttccccattc
     8941 caagagtttt gcccgcatca tatcgacgaa atctttttct gagccagcaa ttttctcagc
     9001 tagggcaata gcggcgctgt tggcactaga taccagagtt gcttcaagca actcttcgac
     9061 agtataatta cgggcctcca taggaatatt actggcttca gaatttgtcg tcaattgata
     9121 aggataatca gaaatatcta caggagtgga gagggtaata cttccgtttt ccaaagcttc
     9181 atagaccaga taaacagtaa tcaattttgt tatggaagca atttcgacag gttgcgttgc
     9241 atccttctca tagagaattt taccagtatt tgcctcaaca gcaatcgcat gtttagcggc
     9301 aatggtaaaa tcttgagcaa cagcagtaga agcaccccct aaaagagaga cagttaacaa
     9361 agttaaaaat atttttttca tagtagtttt attctatcat aaagaaaaaa aatattcttg
     9421 ctttaataat tcatctgtta agctttttga aaatatggta aaataaagtg agggaggtaa
     9481 ctcatgtttc gtagaaataa attatttttt tggaccacag aaattttact cttaaccatc
     9541 atcttttacc tatggagaca gatggggtct ttgattaacc cttttgttag cgtgcttaat
     9601 acaattatga ttccattttt attagggggc tttctttatt atttgacaaa ccctattgtt
     9661 actttcttaa ataaagtctg taaactcaat cgtttgcttg gtattttaat taccttgtgt
     9721 actttggtct ggggaatggt cataggtgtt gtctatctct tgcctatttt gattaatcag
     9781 ttatctagtt tgattatatc tagtcaaact atttatagtc gagtacaaga cttaatcata
     9841 gacttatcta attatcctgc gctccagaat ttggatgtag aagctacaat tcagcagtta
     9901 aacttatcct atgttgatat tcttcaaaat atcctaaata gcgtatcaaa tagtgtgggg
     9961 agcgtcttgt cagctcttat cagtactgtt ttgattttga ttatgactcc agtttttttg
    10021 gtttatttct tattagatgg acataaattc ttgcccatgc ttgaaagaac gattctaaag
    10081 agggatcgct tgcatattgc aggcttatta aagaatttaa atgcgacgat tgctcgctat
    10141 attagtggag tttcgattga cgcaatcatt ataggttgtt tggcttatat tggctatagt
    10201 attattggtt taaaatatgc tttagttttt gccatttttt ctggtgtagc caatttaatt
    10261 ccttatgtgg ggccaagtat tggtttgatt cctatgatca tcgcaaatat attcactgat
    10321 ccccatagac tgctgattgc agtgatttat atgcttgttg ttcagcaggt agatggcaat
    10381 atcttatatc ctcgaatcgt aggaagtgtt atgaaggttc atccaatcac gattttagtt
    10441 ttacttttgt tgtcaagcaa tatctatggt gtagttggaa tgattgtcgc agtgccaacc
    10501 tattctatct tgaaagaaat ttctaagttc ttatcccgtt tgtatgaaaa tcataaaata
    10561 atgaaagaac gagaaagaga attagctaag taaaagtcag gagaaccctg atttttcttt
    10621 actggaagtg gcctttagat tagaagactg aaaataagtt aaagtcttaa actaattttc
    10681 acagctaaga atagtagaag ttaatctgat aaaaatcgaa aaaaccagtg gaattccgtg
    10741 tcagggtaag ttccactggt tttcatagtc tattaaagtt cgaatgaaac ctatttatag
    10801 tatattgaaa ctagaatagt acacctctaa ttctaaaaca ttgttagaaa tcgatttgac
    10861 tgtcctaatc tattcgtcct attcttattt cattttacta tattttggtg caataagtga
    10921 aaagtagtcc gaataatata aggattgatt ttatagtttt taaactcaaa tgaattaaaa
    10981 taaagagagt acgaaaattc tcatctgaaa gtattttaga ataattctct tcgtgaattt
    11041 cttcaaaaca gatagcttca tcttaggtat gtgttaattg gatttcgtaa gctctattta
    11101 caatcgtaaa gttatgcact gagaaagttg tagttagtct tccagtttgc taaatttttc
    11161 gaatagtatc ttttttaggt atgtgatttc tttttgcatt tttgagttag ataaggtata
    11221 atggttttat tgtcttttgg ggtcgttacg gattcgacag gcattatgag gcatattttg
    11281 cgactcgtgt ggcgacgtaa acgctcagtt aaatataact gcaaaaaata acacttctta
    11341 cgctctagct gcttaaaaac cagcaggcgt gacccgattt ggattgctcg tgttcaatga
    11401 caggtcttat tattagcgag atacgattaa gccttgtcta gcggcttgat aagagattga
    11461 tagactcgca gtttctagac ttgagttatg tgtcgagggg ctgttaaaat aatacataac
    11521 ctatggttgt agacaaatat gttggcaggt gtttggacgt gggttcgact cccaccggct
    11581 ccattattcc tttgcattct tttgcattcc ttggtaaaac gttgttaaat caacgttttt
    11641 tatttttatc tttggtattc ctttgcattc ttttgctaaa aagggagtca caaacagacc
    11701 ctattttaaa aaaggataga aaaaaggata caacatttgt cgcatcctaa aaataatctt
    11761 ttttccacgg aagacatggg attcgaaccc acgcacgcta ttacacgcct accgcgtttc
    11821 caacacggcc tcttaagcct cttgagtaat cttccaatac ttactcaaat agtctaccat
    11881 aaaggctctt atcttgcaat aaaaattcta gaaataagaa aaatgataga ttttgaaaga
    11941 aaatgataaa aaatgcttga cttcaaaaga aagtatgata gaatgaatag tgtaaacgat
    12001 aacaggaggt gattcggtgt taaaaacaga gcggaagcaa ctgattttag aggagttaaa
    12061 tcaacatcat gtagtttctc tagaaaaatt agttagtttg ctagaaacgt cagaatcaac
    12121 ggttcgaaga gacttggatg agttggaagc ggaaaacaag cttcgtcgtg tgcatggtgg
    12181 agcagaactc ccccactcct tacaggaaga agaaaccatt caagaaaaat ctgtcaaaaa
    12241 ccttcaagaa aagaagttgc tggctcagaa agcagcctct ctcattaaag aaaaagatgt
    12301 catctttatc gatgctggaa caacaactgc ttttttgatt catgaattgg tcaataagaa
    12361 tattacagtt gtgaccaact ccattcacca tgccgctcag ttggttgaaa agcagattcc
    12421 aactgtcatg gttggaggaa acgtcaagac ggcgacagat gctagtatcg ggggcgttgc
    12481 tcttaaccag attaaccaat tgcactttga ccgtgccttt atcggaatga atggtgttga
    12541 cgatggctat tatacgactc ctgatatgga ggaaggagct gtgaaaagag ctattttgga
    12601 gaatgccaag cagacctacg tcttggtgga ttcgtcaaaa attggacaaa cttgctttgc
    12661 caaggtagca ccactcaaac gcgctatcgt tatcactagt caagggcatg agctcttgca
    12721 ggttattaag gagaaaacgg aggtaataga agtatgattt atacagtcac actcaatcca
    12781 tccattgact atatcgttcg tttggaccaa gtcaaagttg gtagtgtaaa tcgtatggac
    12841 agtgatgata agtttgctgg tgggaaagga atcaatgtca gccgtgtctt gaaacgtttg
    12901 aatataccaa atacagcgac gggatttatc ggtggcttta ctggtaaatt tatcacagat
    12961 actttagcag aggaagaaat cgagacacgt tttgtccagg tggcagaaga tactcgtatc
    13021 aatgttaaaa tcaaagcaga ccaagaaaca gaaatcaacg gaacgggtcc aactgttgaa
    13081 ccggttcagc tagaagaatt gaaagctatt ttatctagtc tgacagcaga agatacagtt
    13141 gtctttgcag gttcaagtgc taaaaatcta ggcaatgtta tctataagga tttgatttcc
    13201 ttgacgcgcc agactggtgc gcaagtggtc tgtgactttg aaggacagac cttaattgat
    13261 agtttggact accagcctct tcttgtaaaa ccaaacaatc atgaacttgg agcgattttt
    13321 ggggttaaac tcgaaagttt agatgaaatt gagaaatacg ctcgtgagtt actggctaag
    13381 ggtgctcaaa atgttattat ctctatggct ggtgatggcg cccttcttgt cacatctgag
    13441 ggagcttact tcgctaaacc aatcaaagga acagtcaaaa attcagttgg agctggtgat
    13501 tctatggttg ctggattcac aggtgaattt gtcaaatcaa aagacgcagt agaagccttc
    13561 aaatggggag tggcttgcgg aacggcaact accttctcag atgacttggc aacggcggaa
    13621 tttattaaag aaacatatgg aaaagttgag gtagaaaaaa gatgaaaatt caagacctat
    13681 tgagaaaaga tgtcatgttg ctagatttgc aggcaactga aaaaacagct gtcatcgacg
    13741 agatgattaa aaatttgaca gagcacagtt atgtaacaga ttttgaaaca tttaaagaag
    13801 gaattttggc gcgtgaagct ttgacttcta ctggtttggg tgatggaatc gcaatgcctc
    13861 acagcaaaaa cgctgctgtc aaagaagcga cagttctatt tgctaagtca aataagggtg
    13921 ttgactacga gagcttggat ggacaagcaa ctgacctctt cttcatgatt gcagctccag
    13981 aaggtgccaa tgatactcac ttggcagcct tggcagaatt gtctcaatac ttgatgaaag
    14041 acggttttgc agacaaactt cgtcaagcaa catctgcaga ccaagttatc gaactttttg
    14101 accaagcttc agaaaaaact gaggaacttg ttcaagtacc tgctaatgac tctggtgact
    14161 ttatcgtagc tgttacagct tgtacaacag gtattgccca cacttacatg gcccaagaag
    14221 cccttcaaaa agtagctgct gaaatggggg ttggtatcaa ggtcgaaacc aacggtgcta
    14281 gcggtgttgg aaatcaacta actgcagaag atatccgtaa ggctaaagct attatcattg
    14341 cagcagacaa ggccgttgaa atggatcgat ttgatggaaa accattgatc aatcgtccag
    14401 ttgctgacgg tatccgtaag acagaagagc taattaactt ggctctttca ggagatactg
    14461 aagtctaccg tgccgctaat ggtgcaaaag ctgcaacagc ctctaacgaa aaacaaagcc
    14521 ttggtggtgc cttctacaaa cacttgatga gtggtgtatc tcaaatgtta ccattcgtta
    14581 tcggtggtgg tatcatgatt gcccttgcct tcttgattga cggtgctttg ggtgttccaa
    14641 atgaaaacct tggcaatctt ggttcttacc atgagttagc ttctatgttc atgaaaattg
    14701 gtggagctgc ctttggtttg atgcttccag tctttgcggg ttatgttgcc tactctattg
    14761 ctgaaaaacc aggtttggta gcaggtttcg tggctggtgc tattgccaaa gaaggttttg
    14821 cctttggtaa aattccttat gccgcaggtg gtgaagcaac ttcaactctt gcaggtgtct
    14881 catctggttt cctaggtgcc cttgttggtg gatttatcgc aggtgccttg gttcttgcca
    14941 tcaagaaata cgttaaagtt cctcgttcac tcgaaggtgc taaatcaatc cttctattgc
    15001 cacttcttgg aacaatcttg acaggatttg ttatgctagc tgtgaatatc ccaatggcag
    15061 caatcaacac tgctatgaat gacttcctag gcggtcttgg aggaggttca gctgtccttc
    15121 ttggtatcgt ccttggtgga atgatggctg ttgacatggg tggaccagtt aataaagcag
    15181 cttatgtctt tggtacaggt acgcttgcag caactgtttc ttcaggtggt tctgtagcca
    15241 tggcagcagt tatggctgga ggaatggtgc caccacttgc aatctttgtc gcaactcttc
    15301 ttttcaaaga taaatttact aaggaagaac gtaactctgg tttgacaaac atcatcatgg
    15361 gcttgtcatt tatcactgag ggagcgattc catttggtgc cgctgaccca gctcgtgcga
    15421 ttccaagctt catccttggt tcagcagtag caggtggact cgttggtctt actggtatta
    15481 aactcatggc gccacacgga ggaatcttcg ttatcgccct tacttcaaat gctctccttt
    15541 acctcgtttc tgtcttggta ggagcaatcg taagtggtgt ggtttatggt tacctacgca
    15601 aaccacaagc ataaaaaata gaaaaatgaa aagattggac cgtttggtgc agtctttttc
    15661 tctttccgaa atgcctgtga aatatggtat aatagaagaa tggcaaacaa gaatacaagt
    15721 acaacaagac ggagaccgtc taaagcagaa ctggaaagaa aagaagcgat tcaacgaatg
    15781 ttgatttcgt taggaattgc gattttattg attttcgcag ccttcaaatt aggggctgca
    15841 ggtataaccc tttataattt aattcgcttg ctagtgggta gcctagctta tctggcgata
    15901 ttcggcctat taatctatct cttttttttc aagtggatac gaaaacagga aggactctta
    15961 tctggctttt tcaccatatt tgctggctta ctcttgattt ttgaagccta cttggtttgg
    16021 aaatatggtt tggacaagtc cgttctaaaa gggaccatgg ctcaggttgt gacagatctg
    16081 actggttttc gaacgactag ttttgctgga gggggcttga tcggggtcgc tctttatatt
    16141 ccaacagctt ttctcttttc aaatatcgga acttacttta ttggttctat cttgatttta
    16201 gtgggttctc tcctagtcag cccttggtct gtttacgata ttgctgaatt tttcagtaga
    16261 ggctttgcca aatggtggga agggcacgag cgtcgaaaag aggaacgctt tgtcaaacaa
    16321 gaagaaaaag ctcgccaaaa ggctgagaaa gaggctagat tagaacaaga agagactgaa
    16381 aaagccttac tcgatttgcc tcctgttgat atggaaacgg gtgaaattct gacagaggaa
    16441 gctgttcaaa atcttccacc tattccagaa gaaaagtggg tggaaccaga aatcatcctg
    16501 cctcaagctg aacttaaatt ccctgaacag gaagatgact cagatgacga agatgttcag
    16561 gtcgattttt cagccaaaga agcccttgaa tacaaacttc caagcttaca actctttgca
    16621 ccagataaac caaaagatca gtctaaagag aagaaaattg tcagagaaaa tatcaaaatc
    16681 ttagaagcaa cctttgctag ctttggtatt aaggtaacag ttgaacgggc cgaaattggg
    16741 ccatcagtga ccaagtatga agtcaagccg gctgttggtg taagggtcaa ccgcatttcc
    16801 aatctatcag atgacctcgc tctagccttg gctgccaaag atgtccggat tgaagcacca
    16861 atccctggga aatccctaat cggaattgaa gtgcccaact ccgatattgc cactgtatct
    16921 ttccgagaac tatgggaaca atcgcaaacg aaagcagaaa atttcttgga aattccttta
    16981 gggaaggctg ttaatggaac cgcaagagct tttgaccttt ctaaaatgcc ccacttgcta
    17041 gttgcaggtt caacgggttc agggaagtca gtagcagtta acggcattat tgctagcatt
    17101 ctcatgaagg cgagaccaga tcaagttaaa tttatgatgg tcgatcccaa gatggttgag
    17161 ttatctgttt acaatgatat tccccacctc ttgattccag tcgtgaccaa tccacgcaaa
    17221 gccagcaagg ctctgcaaaa ggttgtggat gaaatggaaa accgttatga actctttgcc
    17281 aaggtgggag ttcggaatat tgcaggtttt aatgccaagg tagaagagtt caattcccag
    17341 tctgagtaca agcaaattcc gctaccattc attgtcgtga ttgtggatga gttggctgac
    17401 ctcatgatgg tggccagcaa ggaagtggaa gatgctatca tccgtcttgg gcagaaggcg
    17461 cgtgctgcag gtatccacat gattcttgca actcagcgtc catctgttga tgtcatctct
    17521 ggtttgatta aggccaatgt tccatctcgt gtagcatttg cggtttcatc aggaacagac
    17581 tcccgtacga ttttggatga aaatggagca gaaaaacttc ttggtcgagg agacatgctc
    17641 tttaaaccga ttgatgaaaa tcatccagtt cgtctccaag gctcctttat ctcggatgac
    17701 gatgttgagc gcattgtgaa cttcatcaag actcaggcag atgcagacta cgatgagagt
    17761 tttgatccag gtgaggtttc tgaaaatgaa ggagaatttt cggatggaga tgctggtggt
    17821 gatccgcttt ttgaagaagc taagtctttg gttatcgaaa cacagaaagc cagtgcatcc
    17881 atgattcagc gtcgtttgtc agttggattt aaccgtgcga cccgtctcat ggaagagctt
    17941 gagatggcag gtgtcattgg tccagctgaa ggtaccaagc caagaaaagt attgcagcaa
    18001 taaaaaatag cttctttcca aggttggaag gagctatttt actggctatt gattactttt
    18061 atactcttcg caaatctctt caaaccacgt cagcttcgcc ttgccgtact caagtactgt
    18121 ctacggctag cttcctagtt tgctctttga ttttcattga gtattatttt ctgaagttgg
    18181 agtattgggc tgtttttcat tttcagtggc aggtttactt gtagcaggtg tagtagagtc
    18241 ctgagttgct gttttctgat cttctttttt ctcttccttg acgctagatt ttggcgtttc
    18301 ttcttgttgt gttttttctt gagaagtgtt attttcctta tttggagtag tattttcctg
    18361 aggggattct ttttgaattt ctttgacaaa ggttgtcgtc tggcttgtcg taggttcttt
    18421 tttagtattt ttattattat tatccaaggc gttcatgatc gtgatacccg cggtaatcaa
    18481 accaaggata ctaccgatag tagtaatggt tttttgaaaa acagtaaagc cttttttgat
    18541 atgttctgtt ttcggttttg aagttctacg atagttagac atacattctc tcctttgatt
    18601 atgatttatt atactctgtt tctttaaaaa aatcttaaaa aaagagaaat tgccctttct
    18661 tgtcgcaggc tccgtttcat gatacaatag aaggagtgat tttagaaagc gtgagaaaca
    18721 tgatttactt tgataattcg gcgacgacca ggccctatcc agaagccctt gaaacctata
    18781 tgcaggtggc ttcaaaaatt ttaggaaatc catctagtct ccatcgtttg ggagaccagg
    18841 caacacgaat tttagatgct tcccgtcaac agattgcaga tttaatcggt aagaaaagtg
    18901 atgaaatctt ctttacatct ggtgggacag aaggggataa ctggatcatc aagggagtag
    18961 catttgaaaa agcccagttt ggcaagcaca tcatcgtatc agccattgaa catccagcag
    19021 ttaaggaatc agccctctgg ttgaaagctc aaggttttga agtggatttt gctccagttg
    19081 ataacaaagg atttgtggat gttgaggcgc tagaagattt gataagacct gatacgaccc
    19141 tcgtttccat catggctgtg aacaatgaaa tcggctctat ccaacctatt gaggctattt
    19201 cagaattctt ggcagacaag ccaactattt ccttccacgt tgatgcggtt caggcgcttg
    19261 ccaagattcc gactgaaaag tatctgacag aacgagtgga tttcgcgact ttctctggtc
    19321 acaagttcca cggaatccgt ggtgttggtt ttatctatat caagtctggc aagaagatta
    19381 cgcctctttt aacaggtggt ggtcaggaac gtgattaccg ttcgacaact gaaaatgtgg
    19441 caggaattgc agcgaccgct aaggctctcc gtttatctat ggaaaagcta gatatcttta
    19501 ggagcaagac tgggcagatg aaggcagtga ttcgtcaagc acttctggac tatccggata
    19561 tatttgtctt ttcagatgag gaagacttcg cccctcatat tctgactttt ggaatcaagg
    19621 gtgttcgtgg tgaggtcatt gttcacgcct ttgaagacta tgatattttc atctcaacga
    19681 cctcggcttg ttcgtccaag gctgggaaac cagccggaac cctgattgct atgggagtgg
    19741 acaaggataa ggctcagtca gctgtgcgtc ttagtctaga ccttgaaaat gatatgagtc
    19801 aggtcgagca gttcttgacc aagctaaaat taatttacaa tcaaactaga aaagtaagat
    19861 aggagcattc atgcagtatt cagaaattat gattcgctac ggtgagctgt caaccaaggg
    19921 caaaaatcgt atgcgtttca tcaataaact tcgcaataat atttcagacg ttttgtctat
    19981 ctatccccaa gttaaggtaa cagcagatcg cgaccgtgcc cacgcttacc tcaatggagc
    20041 agattacaca gcagtagcag aatcgctcaa acaagtattt ggaattcaaa acttttcccc
    20101 tgtttataag gttgaaaaat ctgtagaagt tctgaagtct gctgtccaag agattatgca
    20161 ggacatctac aaggaaggca tgacctttaa aatctctagc aagcgtagcg accacacctt
    20221 tgaattggac agtcgtgaac tcaaccaaac gcttggaggg gctgtattcg aagccattcc
    20281 aaacgtacaa gctcaaatga aaagtcctga catcaatctt caggtggaga tacgtgaaga
    20341 agcagcctat ctttcttatg aaaccgttcg aggggcaggt ggattaccag tgggaacttc
    20401 tggtaagggc atgctcatgt tgtcaggggg aatcgattcc cctgtagctg gctatctagc
    20461 gcttaaacga ggggtagata tagaggcagt tcactttgcc agcccacctt acacgagtcc
    20521 tggtgctctt aaaaaagccc aagatttgac ccgtaaatta accaaatttg ggggaaatat
    20581 ccagtttatc gaagttcctt ttacagagat tcaagaggaa atcaaagcca aagcgccaga
    20641 agcctacctt atgaccttga cgcgtcgttt tatgatgcgt attactgacc gtattcgtga
    20701 ggtacgaaat ggtttagtta tcatcaatgg ggaaagtcta ggtcaagtag ccagccaaac
    20761 ccttgaaagt atgaaggcta tcaatgctgt taccaacact cccatcattc gtcctgtggt
    20821 taccatggac aagttggaaa tcattgacat cgcccaggaa atcgatacct ttgacatttc
    20881 aatccaaccg tttgaagact gttgtactat ttttgcacca gatcgtccaa aaacaaatcc
    20941 taaaattaag aatgcggagc agtacgaagc gcgtatggat gttgaaggct tggttgagcg
    21001 agcagtggct ggaatcatga ttactgaaat cacacctcaa gccgaaaaag atgaagttga
    21061 tgacttgatt gacaatctgc tctaattcag aaaatccaaa agaatagcga aaatcagtaa
    21121 aaaaagttag ttttttctct aaaaacaggt aaaaaactaa ctttttttat ttttatgata
    21181 taatgatata aaattttgaa tatagagagt tttctgacaa tgaatcaatc ctacttttat
    21241 ctaaaaatga aagaacacaa actcaaggtt ccttatacag gtaaggagcg ccgtgtacgt
    21301 attcttcttc ctaaagatta tgagaaagat acagaccgtt cctatcctgt tgtatacttt
    21361 catgacgggc aaaatgtttt taatagcaaa gagtctttca ttggacattc atggaagatt
    21421 atcccagcta tcaaacgaaa tccggatatc agtcgcatga ttgtcgttgc tattgacaat
    21481 gatggtatgg ggcggatgaa tgagtatgcg gcttggaagt tccaagaatc tcctatccca
    21541 gagcagcagt ttggtggtaa gggtgtggag tatgctgagt ttgtcatgga ggtggtcaag
    21601 ccttttatca agcacaagac aggttggttt gatggcatga tgacgacagg ttgctctatg
    21661 ggagcctatc atgcactcaa tttcttcctc cagcatccag atgtctttac caaagtgatt
    21721 gctctcagtg gtgtttacga cgcacgtttc tttgtcggtg attactacaa cgatgatgct
    21781 atttaccaaa actcgccagt agattatatt tggaaccaaa acgacggctg gtttattgac
    21841 cgttaccgtc aggcagagat tgtgctgtgt acggggcttg gagcctggga acaagatggt
    21901 ttgccatcct tttacaagct caaagaagcc tttgacaaga aacaaattcc agcctggttt
    21961 gctgaatggg gacatgatgt cgcccatgac tgggaatggt ggcgtaaaca aatgccttat
    22021 ttcctcggta atctctattt ataaaaggag ttacctatga attaccttgt tatttctccc
    22081 tactatccac aaaactttca acagtttacc atcgaactag ctaataaagg catcacagtc
    22141 ttgggaattg gtcaagagtc ttacgagcaa ttggatgagc ccttgcgcaa tagcttgacc
    22201 gagtattttc gtgttgataa tcttgagaac atagatgaag tcaaacgtgc agttgctttt
    22261 ctcttttata aacatggtcc aattggccgc atcgagtctc acaatgaata ctggcttgag
    22321 ctagacgcaa cactcagaga acaattcaat gtttttggtg ccaaaccaga ggatctcaaa
    22381 aagacgaaat ataagtctga aatgaagaaa cttttcaaaa aagcaggtgt tcctgtggta
    22441 cctggagctg ttatcaagac ggaagcagat gttgatcaag cagtgaaaga aatcggtctt
    22501 ccaatgattg ccaaacctga taatggagtg ggagcagccg caacctttaa acttgagaca
    22561 gaagacgata tcaatcactt caagcaagaa tgggaccatt caacccttta tttctttgaa
    22621 aaatttgtca cttccagcga aatctgtacc tttgacgggc tcgtggacaa ggatggaaag
    22681 attgtcttct caacaacctt tgactacgcc tatacaccgc ttgacctcat gatttataag
    22741 atggacaatt cttattatgt gctcaaggat atggatccta aactgcgcaa gtatggggaa
    22801 gcaattgtca aagaatttgg tatgaaagaa cggtttttcc atattgagtt cttccgtgag
    22861 ggggacgatt atattaccat cgagtacaat aaccgccctg caggtggttt taccattgat
    22921 gtttataact ttgctcattc cttggacctt tatcgtggct atgcagctat tgtcgcagga
    22981 gaagagttcc cagcgtcaga ctttgaaact cagtattgtt tggctacttc tcgccgtgca
    23041 aatgctcact atgtttattc agaagaggat ttgcttgcca aatatagcca gcagttcaag
    23101 gttaaaaaag tcatgccagc tgccttcgcg gaacttcaag gagattacct gtatatgctg
    23161 accactccga gtcgacaaga aatggagcag atgattgcag atttcggaca acgtcaagaa
    23221 taagaactat cggattaagg aaattaactc ccttaatcct tttgttttgt ctgataaaaa
    23281 ataagagcat cccaacaagg tagctatcat aaaacttgtt cgataactat ttgaagcagg
    23341 attaggtggt cagaaattaa attttaatat ttcaattgag tcatagtatt gtgtttgcgt
    23401 atccttaaat cagctaaaag gatccatgac gacacctata cgatatagtt ttcaagatac
    23461 caaacaagtc tattaatatt caatgaaaat caaagagcaa actaggaagc tagccgcagg
    23521 tttctcaaaa cactgttttg aggttgtgga tagaactgac agagtcagta tcatatacct
    23581 acggcaaggt gaagctgacg tggtttgaag agattttcga agagtataaa atattcaggt
    23641 gacgcataga tatagttaat tgaagctttg tttgaaatct gataaaataa tgatattact
    23701 aagttttaaa aactaaagaa aagggaagat atgattacag gcgaattaaa aaataaaatc
    23761 gatcagctgt gggaaattct ttggacagaa ggaaacgcaa atcctttaac aaatattgaa
    23821 cagttgactt atctcttatt tatgaaagat ttggatagtg tcgagcttgg acgtgaaagt
    23881 gatgctgaat ttctagggat tccttatgag ggagtttttc caaaagataa acctgaatac
    23941 cgttggtcaa cttttaaaaa tataggagat gctcaggaag tttatcgttt aatgactcag
    24001 gagatttttc cgtttattaa aaatctcaag ggggatacag atgatacagc cttttcacga
    24061 tatatgcgag aagctatttt tcaaataaat aaacctgcta cgcttcaaaa ggcaatttct
    24121 atcttagatg tttttccaac taggggatta gatgtagatt ttgataatga caaacaaagt
    24181 attactgata tcggagatat ctatgaatat ctgttatcaa aattgtcgac cgcaggtaaa
    24241 aatggacagt tccgtacacc tcgtcacatc atcgatatga tggttgagtt gatgcaaccg
    24301 actatcaaag atatcatctc agatcccgct atgggttctg ctggcttctt agtatctgct
    24361 agccgttact taaagcgtaa gaaagatgaa tgggaaacca atacagataa tatcaatcat
    24421 tttcataatc agatgtttca tggaaatgat acggatacga ctatgttgag acttggggcg
    24481 atgaacatga tgctacatgg agtagaaaat ccacaaatca gttaccttga ctcgctgtct
    24541 caagataatg aagaagccga taaatatact ttggttttag caaatcctcc ttttaagggc
    24601 tcacttgact acaattcaac ctctaatgac cttcttgcaa ccgtaaaaac caaaaaaaca
    24661 gaattactct ttctttctct tttcttgcga actttaaaac caggtggacg agcagcagtt
    24721 atcgtacctg atggtgtcct ttttggttcg tctaaagctc ataaaggaat tcgtcaggaa
    24781 attgtagaga atcataagct tgatgctgta atctcaatgc ctagtggtgt gttcaagcct
    24841 tatgctggag tttcaactgc cattctcatc tttacaaaaa ctggtaatgg tggtactgac
    24901 aaagtctggt tttacgatat gaaagcggat ggtttaagtt tggatgataa gcgacaaccg
    24961 attagcgaca atgatattcc agatattatc gaacgctttc atcatcttga aaaagaagca
    25021 gaacgtcaga gaacggatca atctttcttt gttccagttg ctgagataaa ggaaaatgat
    25081 tatgatttgt ctatcaataa atataaagag attgagtatg aaaaagttga gtatgaacca
    25141 acagaggtca tcttaaagaa aatcaatgat ttagaaaaag aaattcaagc tggcttggct
    25201 gaattagaaa aattactcaa gtagagaggt ggctgtatga aaaaagtgaa gttgggggaa
    25261 gtcttatctc taaaaaaagg caagaaagcc actgtacttg ctgaacaaac aactctaagc
    25321 caacgttata ttcaaataga tgatttaaga aataataata atttaaaatt cactgaaagt
    25381 ttaaatatga ctgaagcact cccagatgat attctgatag catgggatgg agctaatgca
    25441 ggaacagttg gttatggatt atcgggagct gttggtagta caattacggt cttaaaaaag
    25501 aatgagcgat acaaagaaaa aattatatca gattacttgg gagtcttttt ggaaagtaaa
    25561 tcgcagtatt tacgagaaca ttcaacaggt gcaacaattc ctcatttaaa caagaatata
    25621 ttacttgatt tacaattaga attgctaggt atcgaagaac aagagaacat tatctgtatt
    25681 cttaatacga ttaaaaggct tattactaaa agaaaattgc agttagatga actaaacttg
    25741 ctcgtcaaat cccgatattc cgaggaggtg gttgcatgaa gaaggtgaaa ttaggtgaag
    25801 tggctacttt tatcaatggc tatgctttta aacctcaaga ttggtcatct gaagggaaag
    25861 agattatcag aatacagaat ctgactaaaa cttcaacaga gataaattat tattcgggta
    25921 cgattgataa aaaatacatt gttgaagctg gtgatattct tatttcgtgg tcgggtacat
    25981 taggggtttt tcagtggcgt ggaagatccg cagtgttaaa tcagcacatt tttaaagtgg
    26041 tttttgataa gatagatata gataaatcgt attttaaata tgttgttgaa aaaggtttac
    26101 aagatgctgt aaaacatact catggttcca caatgaaaca tttaactaaa aaatattttg
    26161 ataatattat agttccatat acaaatttgg gagagcaaca aagaattgca agtgagctgg
    26221 atttgttaag caagctgatt ttaaggagac aagaacaact tgaagagctt aatctacttg
    26281 taaaatcccg atttaacgag atgtttgggg aaaataaaat atttgaaagc attgataact
    26341 tatttgatat tatagatggt gataggggca aaaattatcc taaatcagat gagttgttta
    26401 gtgaggagta ctgtttattt ttaaatacaa agaatgttac taaaaacgga ttttcattcg
    26461 atacaaagca atttatcact aaaacaaagg ataaattact tcgaaaaggc aaacttgagc
    26521 gttatgatat agtcttgaca acaagaggta ctgttggaaa tgtagcgtac tacgatgaat
    26581 taataaaata taaacattta cgtataaatt caggtatggt aatattacgt cccaagacac
    26641 caaatctaaa tcagaaattt attatccatg ttttaaggaa taataattat agtcgagtga
    26701 tatcaggaag tgctcagcct cagttaccaa ttacaaaatt aaaaaaaata cttctccccc
    26761 ttcccccact agccctccaa aatgagttcg cagactttgt agccctggtc gacaaatcac
    26821 aattggcaat ccaaaaatct ctggaagaac ttgaaacttt gaagaaatct ctgatgcagg
    26881 agtattttgg ctgatattct gccattgtaa ttacggtaat gatttgttat aatacttcaa
    26941 aggaggaaat cagatggtag taaaaacaag aaaacaagga aattcaatca ccattacgat
    27001 tccaagtgaa tttaatattc caagtggtgt taaatacgaa gcgaaattgt taccaagtgg
    27061 tgagattatc tttactcctg aagaattggg gcagcaggtt tcttatgtat ctgatgatgc
    27121 ctttgactta aatttagata aaatatttga cgaatacgac gatgttttca aagctttggt
    27181 ggaaaaatga caatctatct gacagaaaag caaattgaaa aaataaatgc tttagcaatt
    27241 caacggtatt ctccaaatga gaaaattcaa acagttagtt cttctgcctt aaatatgatt
    27301 gtgaacttac cagaacaatt tgtctttggg aagtctcttt atccaacaat ttttgataaa
    27361 gcaacgatac tatttgtcca attgataaag aagcatgttt ttgctaatgc taataaaaga
    27421 actgctttct tcgttttggt caaattttta caattaaacg gctatcgttt ttctgtaacg
    27481 gtagaagaag cagtaaaaat gtgtgtaacc atcgcagtag aagctttaac tgatgaaaaa
    27541 atgacaagct actccaaatg ggtttctgaa cattctgtta gagaaaaggt caaaaagtaa
    27601 cctagtatgc tggatttgaa tgagcacaag aaaataaatg aacagacaat attagaattc
    27661 tgtaatgcag aaactgatat tgtctctttt tattgatgaa taagaaagtg agaaattatg
    27721 gaatcaaaag ttacaattat catgcaagaa atgttacctc ttttaaataa tgaacaatta
    27781 ctagcgttga gagagagttt agaacatcat ctagtagacg gaaaaaagca gcagaagtat
    27841 tcgaataata acctgttgca actatttatt accgccaagc aggtagaggg ctgtagctca
    27901 aaaacaattc gttattacca gaggacgatt gaaaacttgt ttaatgctat taaagagtct
    27961 gtgacacaac tcacaacaga tgatttaagg agttatttag caaattacca gtctgaaaag
    28021 gattgtagta aggcaaattt agacaatatt aggcgtatat tgtcttcttt ttttgcttgg
    28081 cttgagcaag aggaatatat cattaaaaat cccattcgac ggataaagaa aattaagact
    28141 gagcaaaatg tgaaggaaac ttatactgat gaacatttgg aaattatgcg tgataactgt
    28201 gaaaatttga gagatttggc aataatagac ctactagcat cgacaggtat gcgtgtaggg
    28261 gagcttgtac agttgaatcg ttcagatatt gattttgaaa acagagagtg tgttgtcttt
    28321 ggtaaaggaa agaaggagag accagtatat tttgatgctc ggacgaaaat tcatttaaga
    28381 aattatctta acgacagaaa agatagtcac cctgctcttt ttgtaacgct agttggaaaa
    28441 gcccagagac ttggaattgc tggtgtagag attcgcttaa gaaagttagg agacaaactc
    28501 ggcatacaaa aggttcaccc acataagttc agaagaactt tagcgactaa ggcaattgat
    28561 aaaggtatgc ctatcgaaca agtccaaaaa ctgctaggtc atagcaagat tgacacaacc
    28621 ctggcctatg ccatggtcaa tcaaaataat gtcaagcatt cacaccaaaa attcatctct
    28681 taaaagcaaa tcccgattta acgagatgtt tggggatcct ttaaataata acaagaaatt
    28741 tgcagtaaaa acgggacaac agtgttttaa attttcaagt ggaaaatttc ttgataaaca
    28801 tgatagagtt tttgaaggtt atcctgccta tggtggaaat ggcattgctt ggaaaagtcg
    28861 aaaatattta attgataatc ctactatcat cattggtcgt gtaggtgcat attgtggtaa
    28921 tgtaagaact acccacggta aggtatggat aagtgacaat gctatatata taaaagaatt
    28981 taagaattcc gatttcaatc ttgtattttt attagaatta atgaaagtaa ttgattttag
    29041 taaatttgct gatttctcag gtcaaccaaa gataactcaa aaaccattag aaaatcagaa
    29101 atatatcctc cccccactag ccctccaaaa tgagttcgca gactttgtag cccaggtcga
    29161 caaatcacaa tttgcttgtg agatagctat aaaagtgtgg agaaatagct tgaaatttag
    29221 tataatatag ctaaactatt tgtttaaagt gagaaaaaaa tgggaaattt tagctttctt
    29281 ttaaaaaatg acgaatatga atctttttca aaaccttgca ttgaagctga aaatatgatt
    29341 gctacatcaa ctgtggctac tgcctttatg gcgcgtcgtg ctttggagca ggctgtccat
    29401 tggatatata gtcacgattc atatttagaa gctccctatc gtgctactct atcttcttta
    29461 gtatgggatg atgattttag ggatatcgta gattctgaac tccacaagca gatagttctg
    29521 ttgattcggt ggggaaacca tgctgctcat ggtggtgaaa ttaaggaacg agaagcgatt
    29581 ttagctttac atcatttgta tcagtttgtt aattttatcg attattgtta cagcaatgaa
    29641 tttgtggagc gttattttga tgagaagtgc ttaccacttt cagcaaacat caaataccga
    29701 gaaactccac aatctatgat aaacttacaa gacagtttac cagaactgcc tgattttcat
    29761 gaacagatgg ctgctcagtc cgtagaagtt caagagactt atactgaaaa acgtgagact
    29821 gcagcgcaac ggcaagatgt gcctttccat attgatcaat tatctgaggc agagacaaga
    29881 aagctcttta ttgatatcga tctccgttta gcaggatgga tatttgaaga aaactgtcgt
    29941 gttgagatag ccgttgatgg tctcaagcac ggttcaggaa ttggttactg tgactatgta
    30001 ctttatggta aaaatgggaa aattttagcg attgtggagg ctaaaaaagc ctctgtcaat
    30061 ccagaagtag gggaagtaca ggtcaaagaa tatgctgaag ctcttgagaa acatatcggc
    30121 tatcagccaa tttgctttat tacaaatggg ttgaagcact atatacttga tggtccgaac
    30181 cgccgccaga ttgcaggctt ttactctcaa gaagaattgc aattagtgat ggatagacgt
    30241 catcttcaaa aaccgcttga ggatatttct agtaaaatta gggacgatat ttccgggcgt
    30301 cactaccaaa aacatgccat tgcaagcgtt tgtgaagctt tctctaatca tcgtagacag
    30361 gcacttttgg ttatggcaac tggggcgggg aaaactcgta cagcagtttc tctagttgat
    30421 atcttatcac gtcataactg ggtaaaaaac gttctcttct tagccgatag aacttccttg
    30481 gttaagcaag cctatgattc gtttagaaaa ttactcccag atctttccgt ttgtaacttc
    30541 ttagaagata aagaaggagc tcaatcaagt cgtatggtct tttcaactta tccgaccatg
    30601 attggagcga ttagtggtca agaagaagta aatcaacgcc cttttactgt tgggcatttt
    30661 gaccttatca taattgacga atctcaccgt tctatttatc agaaatacaa gtccattttt
    30721 gattattttg atgcaagaat tgtaggctta acagctactc cgcgtcaaga tttagataaa
    30781 aacacctatg gattctttaa tttggagaat ggggttccaa catatgcata tgatttggaa
    30841 gaggctgtta aagacggata tttagtagcc tatcattcta tcgaaaccaa actgaaacta
    30901 cctacggatg gtctacatta tgatgatttg tccgaagaag aaaaggaaca ttttgatagc
    30961 aaatttgaag acaatagctg tgaaaaagat attgatggga gtgtatttaa ttcctttatt
    31021 ttcaataaaa gtacagtaga aattgtttta aatgaactca tgacaagagg aattcagaca
    31081 gcctcgggtg atgaaattgg taaaactatt atttttgcta aaaatcatga tcatgcggaa
    31141 tatatcagag gtatttttaa caaccgctat cctgaaaaag ggagcgacta tgctcaggtg
    31201 attgattata gtattaagca ttatcagacc ttgattgatg attttaaaat taaggagaag
    31261 tatcctcaaa ttgcgatttc tgtcgatatg ttagatacag gtattgatgt accagaggtt
    31321 gttaatttag tcttcttcaa gaaagtacgc tctaaaacta agttttggca gatgattggt
    31381 cgaggaaccc gtctatgtaa agatttattt ggacctgagc aggataagga aaacttcttg
    31441 gtatttgatt atggggacaa ttttgattat tttcgtgcag atccaagaga tggagagggt
    31501 cgtcacattg tttcgctgac tcagcgttta tttaatatca aagtggactt gattcgagaa
    31561 cttcagggac tccaatacca agaagatcag tttgcgagag cataccgtca gcagcttgtc
    31621 tcggaacttc aaggtcgtat agagagctta aatgagttgg acttcagggt tcgtatggtt
    31681 ttagatacag tttatagcta taggaaattg gaaagttggc agaatctaac tgctgttaca
    31741 agtgaaacca ttcaaaaaaa tctctctccg cttttatttg atgaagataa agaagatgag
    31801 atggccagga gatttgattt gtggttgctt catattcagt tggggcaact gacagctaaa
    31861 tcttccactg ttcatatttc ccaagtgatg aagacggcta gagctctttc tgctattggc
    31921 aatatcccgc aggtttttga gcaggctgaa attatcagga aagtacagga gcctgaattt
    31981 tggaaagaag ttaacttgtc tgatttggaa aaaattcgtc ttgctattcg agatttatta
    32041 cagtttttgg ataaaacaga ccgtaaaccc tactatgtta actttgaaga tcgtatactc
    32101 tccactgttc acgagaccac agcatttttg caggtcaacg atcttcggtc ttacaatgaa
    32161 aaagttgagc attatttgaa aactcatctg gatgaggagt ccatttctaa gctataccat
    32221 aataaaaagt tgacatctga tgatatgctt gcacttgaaa aattgctttg ggaaaaatta
    32281 ggtagtaaag cagactacca aagtcattat gaaaataagg caattccgag attggttcgt
    32341 gagattattg gcttagatag agagtctgcc aatcgtattt tttctaaatt tttgtcggat
    32401 gagaatctta atgccaggca gatttcattt gtaaaattga ttgtagacta cattgtagaa
    32461 aatggttttt tagagacgaa agtgttaacg caagagccgt ttaaatctta tggttctgtt
    32521 caactactct tccaacacca actaccagta cttcgtaata ttgttcaaat cattgaactt
    32581 atcaataatc gagctggaga agcggcttaa attctaaagt gattgccatg ctgagactca
    32641 tttaaaatta aaaagagtag aaatttatgc tatatatgag aagttttatt aggaagaatg
    32701 tcatcgtttt cctagaatac agtatcagtt gttaagtggt tgataaattt caaagtagat
    32761 acttgtacca cgatgtttgt tgatcgagtt attaacaaaa gagctacttt gattttaaag
    32821 aaatagaaaa caaaaagccg agcaagaatt caattgcagg agaaaatgaa ataatactca
    32881 atgaaaatca aagagcaaac taggaaacta gctgcaggct gctcaaaaca ctgttttgag
    32941 gttgcagatg gaagctgacg cggattgaag agattttcga agagtataaa tcttcctagg
    33001 ataaagcaaa acgcatagta tcaagggttt tcaacacttg atactatgcg ttttctgatg
    33061 ttaaagactt tctaccaggt tttttaaaag cataattgtt agttgtagtc atttattatt
    33121 cttcaaagaa aaatggtggg gcgaattttt tcagttcttc aaagcacttt tgagcagtat
    33181 ctgcatcttc acagatgata agacagacat cattaccaca aagggtagcg atagcgtcag
    33241 ggaagctcaa agtatcaatg atagaaccaa aggattgagc cagtccagga agggttttta
    33301 gtaggacttg gtgttgaact gggcgcatcc agacaagggc gtcttccatg tagagttcga
    33361 gacgtttttc ccattttgag atggaaccat tgttaagaac ataataagcg ctatcttctt
    33421 cgcggacttt tgataggttc atatttttga tgtcgcgtga gagggttgcc tgggttactt
    33481 gaatgtcgtt ctcagcaaga agggcttgca actcagcctg tgtatgaatc ttgttttttg
    33541 tgataagagc gcgtataagt tggtggcggt gttctgattt attcataata atgtaactcc
    33601 ttttagcaag gtaaggtaag catggactga gcgaggtcga cagtcaagtg gtagtctgta
    33661 ttgtcacgga tggtgatttc aaagtcagta gtatagagga ctaaacggag agtgtctcct
    33721 tcttttagct tgtaaatagt tggctgcagt tcaaattgaa cgtccatcca ttcatctgca
    33781 gtaatatcct ctactaacag taaatcattt ctattttgta aattaaggta accttttgtc
    33841 acgactcgtt gtgcctctgg tctaaatggc aattcacaga gattttccaa catgtgatag
    33901 cgaccgttgt caatggttct agcacttaaa atagctggat aaggttgtag gtatttcttt
    33961 tgcccaaatt ctagcagttg ggcagataag agccccttgt ttgtactgga tttgatacga
    34021 agattgagct gagcgcgacc gtttaggtgg agatctttag tcacaggaag gttaatagta
    34081 atctgattgg ctttcccttg atagagctct gtattgaagg tttggtatgt cttaccatag
    34141 cgctcaaaat ccttatctgg gtactggttt tgaatagctt gctcttcttg accaagtgag
    34201 aaggtttcac agttttcttg cccaccgaag ttatcaagtg ataaccaagt ctgtggagct
    34261 gtattgtcct gccagataac agtaggaagt tgaaagtctg tttcctgtcc tagtaatttc
    34321 ttggtcaata aggcatttat ggactcacgg aagtcaattg attgccaatt gttcatgtaa
    34381 acatgggcac cattatggaa aaagagatgc ttgtgtatat gagtaggaag agcatggaac
    34441 atctggtaaa catgaagtgg tttgacattc caatcctgag aaccatgagt aaagacaacc
    34501 tctgccttta ctttatgggc attgagcaga taattgcggt catgccaaaa ctgattgtag
    34561 tccccagttt ttcggtctag ctgagctttc actttttcta agtcagcttg gtgagcttca
    34621 ttgccacgga tatagtcgcc agctaagaga ttacgagaat aggttaactc agcaagggag
    34681 tcaaagtcct cacctggata accacctggg ctagtcacca gaccgttttc acggtagtag
    34741 ttgtaccatg atgaaattcc tgcctcggca atgataactt ctaaaccatc gactcctgta
    34801 gtcgcaagac cattggacat ggtacctaga taggaaagtc ctgttgtagc aacttttccg
    34861 tttgaccaat cagccttgac ttgacgctgg cgcgtgtgat cagtaaaggc acggcaacga
    34921 ccgttaagcc aatcgatgac atttttataa gcctcgattt gctggtagtc tccattagtc
    34981 atgaaacctg tcgagtcttt ggtaccaaca cctgagacat agagattggc aaagcctctc
    35041 ggaaggaagt agtcgtttag tgtatagcta gagttgatgt gagttagctt ttcctcagcc
    35101 tctgctataa gctcagcttt accttggggt tggacgagat ttagttgagg tttctctagc
    35161 tcaatcttgt gaggaagctt aacctcaagc tcgccctcca tcttgtagag agccttgtca
    35221 ctagccttgt cattggttcc ctgatgataa gggctggctg tcatgatggc agggattttt
    35281 ccatcaaaac gagggcgaat aatgctaacc tttactaggt ctgatagccc tttttggtca
    35341 gtatcgacac gagactcaac gtaaacgact tcacgaatga catcctggtt agaaaaagta
    35401 gccaaactct tgccgttaaa gtagtggtag tcattatcct ccggaataag accatcacta
    35461 acaagttggt cgataagagt atttcctttt ttggtgcgag tattgagtaa ctgatagaga
    35521 ttttcaatca agtcaccata tataatggga aatccagttt ctttacgaaa aacgtcacta
    35581 tcttcgaagt caaccaaata agaaaagcct aaaagttgaa aagcaacagt ataaaaaata
    35641 tctgctgtca gttcatcttc tgattgaaaa aatgtcagca ggtctgtttt tttatcagct
    35701 gctaggatag aaagtgggta gttggtgtct tgataagtga aaaagaaacg acgtaaaaag
    35761 gtttcaagtg agtctttgtg attggctgta ttttgtaaat caaagccaca tttttttagt
    35821 tcagataaga cattttcttt tggaaaattg atataactat attgattaaa acgcatagaa
    35881 cctccatata gaatgacagt taaggttatt atatcaaaaa aaaagcagaa agggaattgt
    35941 taaattcaaa aggaaataat ccaataaaaa tgaataaagt actaaattca atatagagaa
    36001 cagagtaaca ataagaataa atagataggg tataaaagtt ctaggagatt tatattatat
    36061 gctttctatt tttatataca atatagtata aatataaaaa tgatgacaaa aatacaaatg
    36121 aatagaaaat aaattagtaa gctgatgaaa tttttctcaa gagaagccat ttataggtga
    36181 aaatggtata atatagtgag aaggatagag gagaagtgta aattgatcgc acaactagat
    36241 acaaaaacag tctatagttt tatggaaagc gtcatttcga tcgaaaagta tgtgagagca
    36301 gctaaagaat acggctacac tcatttggct atgatggata ttgacaatct ttatggcgct
    36361 ttcgactttc tagatattac aaaaaaatac ggcattcatc ctttgctagg gcttgaaatg
    36421 acagtgtttg tagatgatca ggaagtgaat ttgcgctttt tagctctatc tagtgtgggc
    36481 tatcagcagt tgatgaagct ttcgacagcc aagatgcagg gggagaaaac ttggtcagtc
    36541 ctgtcccagt acctggagga tatcgcggtc attgtgcctt attttgatag agttgagttg
    36601 ttagaactag gctgtgatta ctatataggg gtttatccag aaacactagc aagcgaattt
    36661 catcatccta tcttacctct ttatcgggtc aacgcttttg aaagcaggga tagagaagtt
    36721 cttcaagttt taacagcgat taaagaaaat ctaccgctca gagaagttcc cttgcgttcg
    36781 agacaagatg tctttatatc agcaagttct ttagagaaac tattccaaga gtgttttccg
    36841 caagctttgg acaatttaga aaagcttatt tcaggcattt cttacgactt ggatactagt
    36901 ctgaaactgc ctcgttttaa tccagctaga ccagcagtag aggagttgag agagcgtgct
    36961 gaactggggc ttgttcagaa ggggttgact agtaaagaat atcaagatag actagaccaa
    37021 gaattgtctg ttattcatga tatgggcttt gatgattatt tcttggttgt ttgggatttg
    37081 ttgcgttttg gacgatcgaa tggctattat atgggaatgg gaaggggttc tgcagtaggc
    37141 agtttggttt cttatgcctt agacatcacg gggattgacc cagtagagaa aaatctgatt
    37201 tttgaacgct ttcttaatcg tgaacgctat accatgcctg atattgatat tgatatccca
    37261 gatatttatc gtccagattt tatcagatat gttggtaata aatatggtag taaacatgcg
    37321 gcacaaatcg ttactttttc aacctttgga gccaagcaag ctcttcgaga tgtcttgaaa
    37381 cgctttggtg tgccagagta tgaattatct gcaattacta agaaaatcag ttttcgtgac
    37441 aatcttaagt cggcctatga gggcaatctc cagtttcgtc agcaaatcaa tagtaagtta
    37501 gaataccaaa aagcttttga gattgcttgc aagatagagg gctatccaag gcaaacctct
    37561 gtccatgcgg ctggtgttgt aattagtgac caagatttaa ccaactacat tcctctaaag
    37621 tatggtgatg aaattccact gactcagtat gatgctcatg gagttgaggc tagcggactt
    37681 ttgaagatgg actttctggg actacgaaat ttgacctttg tccagaagat gcaagagttg
    37741 cttgctgaaa cagaaggtat tcatctgaaa attgaagaaa tcgatttaga agacaaagaa
    37801 acgttagctt tatttgcctc tggtaataca aaaggtatct ttcaatttga gcaaccaggt
    37861 gccattcgtc tgcttaagcg tgtgcaacca gtctgttttg aagatgtcgt cgcgactact
    37921 tctctaaatc gaccgggtgc tagtgactat atcaataatt ttgtggcaag aaagcatggg
    37981 caggaagaag tgactgttct ggatccagta ctggaggata ttttggctcc aacctacggc
    38041 ataatgctct atcaggagca ggttatgcag gttgcccagc gatttgccgg atttagtctt
    38101 gggaaagccg atattttgcg tcgggctatg gggaaaaagg atgcctctgc catgcatgag
    38161 atgagggctt cctttattca aggttcatta gaagctggtc atactgtgga aaaagcagag
    38221 caggtctttg atgttatgga gaagtttgca ggctatggtt ttaacaggtc acacgcctat
    38281 gcctactcag cattggcctt ccagttggct tattttaaaa cacattatcc agccatattt
    38341 tatcagatta tgttgaattc tgccaacagt gattacttaa tagatgcact tgaagcaggt
    38401 tttgaagtgg cgcctctgtc catcaacacg attccctatc acgataaaat tgccaacaag
    38461 gccatctatc taggtttgaa atccattaaa ggagtcagta atgatttagc tctctggatt
    38521 attgaaaata gaccttattc taacattgaa gattttatag ctaaattacc tgagaattat
    38581 ctgaaacttc ctctgctaga acctttggta aaagttggtc ttttcgattc atttgaaaaa
    38641 aatcgtcaaa aagtatttaa taacttagct aatctatttg aatttgtgaa agagttggga
    38701 agtttgtttg gagatgctat ttatagttgg caggaatcgg aagattggac ggaacaagaa
    38761 aaattttata tggaacaaga gcttttaggg ataggtgtca gcaaacatcc actacaagct
    38821 attgcaagta aggctattta cccgattacc ccaatcggaa atttgtcaga aaatagctat
    38881 gctattattt tggttgaagt tcagaaaata aaagtgattc gtaccaaaaa gggtgaaaat
    38941 atggccttct tacaggcaga tgatagtaag aaaaaattgg atgtcactct cttttcagac
    39001 ttatatcgtc aggttggaca ggaaataaaa gagggagcct tctactatgt aaaaggaaaa
    39061 atacaatcac gtgatggccg tctgcaaatg attgcacaag aaataagaga agcagttgct
    39121 gaacgctttt ggatacaggt gaaaaatcat gaatcggatc aagaaatttc acgtatttta
    39181 gaacaattta aaggcccaat cccagtcatc atccggtatg aagaggaaca gaaaaccatc
    39241 gtttctcccc atcattttgt agctaaatcc aatgaattag aggagaaatt gaatgaaatc
    39301 gttatgaaaa cgatttatcg ctaaaaatac ggaaaataga agaattttaa aatcaaatgt
    39361 gatataatca agaagaatgt taaaagaaaa aggagcataa accaatatga aacgtattgc
    39421 tgttttgact agtggcggag acgcacctgg tatgaacgct gctatccgtg cagttgttcg
    39481 tcaagcaatt tcagaaggaa tggaagtgtt tggtatctat gacggatatg ctggtatggt
    39541 tgccggtgaa attcatcccc tagatgcagc ttcagtagga gacatcattt ctcgtggtgg
    39601 tacttttctt cactcagctc gttatccaga gttcgctcaa cttgaagggc aacttaaagg
    39661 gattgagcaa ttgaaaaaac acggaattga aggtgtagtt gttatcggtg gtgacggatc
    39721 ttaccacggc gctatgcgtt tgactgaaca tggcttccca gctattggtc ttccaggtac
    39781 aatcgataac gatatcgttg gtactgactt tacaattggt tttgacacag cggttactac
    39841 tgccatggac gctatcgata agattcgtga tacatcatca agtcaccgtc gtacttttgt
    39901 aatcgaagtt atgggacgta acgctggtga tatcgctctt tgggctggta ttgcaactgg
    39961 tgctgatgaa atcatcatcc ctgaagcagg cttcaagatg gaagatatcg tagcaagcat
    40021 caaagctggt tatgaatgtg gtaaaaaaca caatatcatc gtcttagctg aaggtgtgat
    40081 gtcagcggct gaatttggtc aaaaacttaa agaagctgga gatacaagcg accttcgtgt
    40141 aacagaactt ggacatattc aacgtggtgg ttctccaact gcgcgtgacc gtgttttggc
    40201 gtcacgtatg ggtgcacatg ctgttaaact tcttaaagaa ggtatcggtg gtgttgcggt
    40261 tggtattcgt aacgaaaaaa tggttgaaaa tccaattctt ggtactgcag aagaaggggc
    40321 attgtttagc cttactgcag aaggtaagat tgtggttaac aacccacaca aagccgatat
    40381 tgagctatct agcttgaata agagcttgtc ataatttaca atttagttaa taagaccaaa
    40441 aaggtcatat atataaagga gtcacaaaaa tcatgaacaa acgtgtaaaa atcgttgcaa
    40501 ctttgggtcc tgcggtagaa atccgtggtg gtaaaaaatt cggtgaggac ggatactggg
    40561 gtgaaaaact tgatgttgaa gcttcagcta aaaacattgc taaattgatt gaagctggtg
    40621 ctaacacatt ccgattcaac ttctcacacg gcgaccacca agaacaaggt gagcgtatgg
    40681 caactgttaa acttgcggaa aaaattgcag gtaaaaaagt tggtttcctt cttgatacaa
    40741 aaggacctga aatccgtaca gaattgttcg aaggtgaagc taaagaatat tcatacaaaa
    40801 ctggtgaaaa aattcgtgtt gcaactaaac aaggaatcaa atcaactcgt gaagtgattg
    40861 cgttgaacgt tgctggtgct cttgatatct atgatgatgt tgaagttggt cgtcaagttt
    40921 tggttgacga tggtaaactt ggtcttcgtg tggttgctaa agatgatgca actcgtgaat
    40981 ttgaagttga agttgaaaac gatggtatca tcgctaaaca aaaaggtgtg aacatcccta
    41041 acactaaaat tcctttccca gctcttgctg aacgcgataa cgacgatatc cgtttcggtc
    41101 ttgaacaagg tatcaacttc atcgcaattt cattcgtacg tactgcaaaa gatgtgaacg
    41161 aagttcgtgc aatctgtgaa gaaactggaa acggacatgt tcaattgttc gctaaaatcg
    41221 aaaaccaaca aggtatcgat aacttagacg aaattatcga agcagctgat ggtattatga
    41281 ttgctcgtgg tgatatgggt atcgaagtac cgttcgaaat ggttccagtt tatcaaaaaa
    41341 tgattatcaa gaaagtcaat gctgcaggta aagttgttat cactgcaaca aacatgcttg
    41401 aaacaatgac tgaaaaacca cgtgcaactc gttcagaagt atcagacgta ttcaacgctg
    41461 ttatcgacgg aactgacgct acaatgctgt caggcgagtc tgcaaacggt aaatacccac
    41521 tcgagtcagt aactacaatg gctacaatcg acaagaacgc tcaagctctt cttaatgaat
    41581 acggacgtct tgattcagat tcatttgagc gtaactctaa gacagaagta atggcttctg
    41641 ctgttaaaga tgctactagc tcaatggata tcaaattggt tgtaactctt actaagacag
    41701 gtcatactgc acgtttgatt tctaaatacc gtccaaatgc tgacatctta gcattgacat
    41761 ttgacgaatt gacagaacgt ggcttgatgt tgaactgggg tgttatccca atgttgacag
    41821 atgctccatc ttcaactgac gatatgttcg aaatcgctga acgtaaagcg gtagaagcag
    41881 gtctcgttga gtcaggcgat gatatcgtta tcgttgctgg tgtgccagta ggagaagctg
    41941 ttcgcacaaa cacaatgcgt atccgcacag tacgttaaga aaaatataaa aacctatcat
    42001 atccagcttt ctagcctgta tgatgggctc tttttttgtc cagggggcaa aaaggggggc
    42061 aaaactttca taatggattg atactcttcg aaaatctctt caaaccacgt cagcgtcgcc
    42121 ttaccgtata tatgttactg acttcgtcag ttctatctac aacctcaaag cagtgctttg
    42181 agcaacctgc ggctagcttc ctagtttgct ctttgatttt cattgagtat gaaataagat
    42241 atgcacaaat tgattagaaa gtcaaatgaa tttctacaaa tgttttagca atcgtaatgt
    42301 acttgtctag attcgatctg atatattttc gatttaatga tatggtattt aaaacctcca
    42361 aagtagcttg ctccattctt ttacttacgt gagtgtagat gttatttact gttttagcgt
    42421 tttagcgttt tagcgttttt gtgttccact ctaaccatta tagcattctt ctcagctagt
    42481 gtactaagga gtgtgtgcct gaaaatatgg gaactaaggg gctggtttat cggtttctct
    42541 agtttagtat ttgccttttg caaagtgatc ttaaatgcct ttctctaaat ttacatatca
    42601 ctattgttta acaaaatcta atctatttta ggtcacttat tctttttttg aaatgtagaa
    42661 tgaacttttt caaagttttt cgaatctttt aaaatttgtt tgttttatat cgccattctc
    42721 cccctttttt aattctccct atatagcctg acaactttcc cgatggtacg aatatggttg
    42781 ctttcgtcta ggtggatgtc ggggtatttg ggattgagtt tttttaaggt agccttggcg
    42841 gagtttcttg acatagttag cgccgtctac ttggaagatg ccgatggtat tatagtcaat
    42901 ctgtggggta ttcttgataa ataggtagtc gctgtttctt atctttggct ccatggactt
    42961 gctgacgaca taagcgattg ggtcgtagtc gtctgggata atggaaactc catatctaaa
    43021 tcgttgtcct gcatcgagcg gctacctgca gagataaact acctaacacg agagtaagta
    43081 gtctgtctgt agtcgtccag tctgatgatt tttacgatac ttcgtttttc tgatcataca
    43141 gttgcctctc ggcataggtc agaactttac cttgtctggg tggtgcccgt tggtcgtaga
    43201 tagattggat atcgctagga gaatcctttt gaactggaga aaagagggca tcaatcaagc
    43261 tactgaatac tttaactaag tcaaatatag tatttttctt agtagaccta accctttttt
    43321 cataatttct aatggtgttt ttacttatac ctatcttagt acccaattct tattgagtcc
    43381 aaccattact agtctatatt gttttatagt tgattgagtt tggaatagta cgctgtagct
    43441 gctaaaacat ttctaggaat taatttgcct ttcctaatag agttgttcat atcttatttc
    43501 aatctactat atttttcgcc tctaacaatc gcaatctctt ctttatctac gaatgaaatc
    43561 gctttctatt tttgtaagta aagcatcaca cgaaatccac gaaaatgaaa acctttgttg
    43621 tgttttcgta aaaaatttgt tgacagagca cgaaacgcct actataatta aatcaagctt
    43681 aaggaaataa caaaaaaaca aatcggaggg aaagacgatg aacacattaa atgagaaagt
    43741 aatcaatatc tgtaaagcag tagttaaaga aactttaatc caagacattt aggagaaaga
    43801 aatgaagaaa tcaagaaaat tagccacatt aggaatctgt tcagccttgt ttttaggctt
    43861 ggctgcttgt caacaacaac atgctacttc tgaggggacg aatcaaaggc aaagcagttc
    43921 agcgaaagtt ccatggaaag cttcatacac caacctaaac aaccaggtaa gtacagaaga
    43981 ggtcaaatct ctcttatcag ctcacttgga tccaaatagt gttgatgcat tttttaatct
    44041 cgttaatgac tataatacca ttgtcggctc aactggctta tcaggagatt tcacttcctt
    44101 tactcacacc gaatacgatg ttgagaaaat cagtcatctc tggaatcaaa agaagggcga
    44161 tttcgttggg accaactgcc gtatcaatag ttattgtctt ttgaaaaatt cagtcaccat
    44221 tccaaagctt gaaaagaatg accaattgct tttcctagat aatgatgcga ttgataaagg
    44281 aaaggtcttt aattcacaag ataaggaaga gtttgatatt ctattttcga gagttccaac
    44341 tgaggcaact acagatgtca aggttcacgc tgaaaagatg gaaacattct tctcacaatt
    44401 tcaattcaat gaaaaagctc gaatgctgtc tgtagtcttg cacgacaatt tggatggcga
    44461 gtatctgttt gtaggccacg ttggggtctt agtacctgct gatgacggtt tcttatttgt
    44521 agagaaattg actttcgaag agccctacca agcgattaaa tttgctagta aggaagattg
    44581 ctacaagtat ttgggcacca agtatgcgga ttatacaggc gagggactgg ctaagccttt
    44641 tatcatggat aatgataagt gggttaaact ttaatagtgt tatgatatga cagtaatctt
    44701 aggattttta tttctatttt tgatgacttg gtgggttatt tcaatcgtta atagccagaa
    44761 accactcaaa aatgaaacat ttattggcta tgtccaaaga tacgatattg atgggaatgg
    44821 ctatcaatca ttaccgtgtc ctcagaactg agaggagttc ttgaaatcgt aaaaccactt
    44881 tgaacaagag ttacttcaac
//
LOCUS       DAVHTH010000014        42779 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.014, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000014 DAVHTH010000000
VERSION     DAVHTH010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 42779)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42779)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42779
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.014"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            complement(19..1977)
                     /gene="ftsH"
                     /locus_tag="VVR63_000764"
     CDS             complement(19..1977)
                     /gene="ftsH"
                     /locus_tag="VVR63_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HEU6128801.1"
                     /translation="MKKQNNGLIKNPFLWLLFIFFLVTGFQYFYSGNNSGGSQQINYT
                     ELVQEITDGNVKELTYQPNGSVIEVSGVYKNPKTSKEGTGIQFFTPSVTKVEKFTSTI
                     LPADTTVSELQKLATDHKAEVTVKHESSSGIWINLLVSIVPFGILFFFLFSMMGNMGG
                     GNGRNPMSFGRSKAKAANKEDIKVRFSDVAGAEEEKQELVEVVEFLKDPKRFTKLGAR
                     IPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAK
                     KAAPAIIFIDEIDAVGRQRGVGLGGGNDEREQTLNQLLIEMDGFEGNEGIIVIAATNR
                     SDVLDPALLRPGRFDRKVLVGRPDVKGREAILKVHAKNKPLAEDVDLKLVAQQTPGFV
                     GADLENVLNEAALVAARRNKSIIDASDIDEAEDRVIAGPSKKDKTVSQKERELVAHHE
                     AGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDMKEQLAGLMGGR
                     VAEEIIFNVQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMLGAQSPQKS
                     ISEQTAYEIDEEVRSLLNEARNKAAEIIQSNRETHKLIAEALLKYETLDSTQIKALYE
                     TGKMPEAVEEESHALSYDEVKSKMNDEK"
     gene            complement(1993..2535)
                     /gene="hpt"
                     /locus_tag="VVR63_000765"
     CDS             complement(1993..2535)
                     /gene="hpt"
                     /locus_tag="VVR63_000765"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HEU6128802.1"
                     /translation="MLENDIKKVLVSHDEITEAAKKLGAQLTKDYAGKNPILVGILKG
                     SIPFMAELVKHIDTHIEMDFMMVSSYHGGTASSGVINIKQDVTQDIKGRHVLFVEDII
                     DTGQTLKNLRDMFKEREAASVKIATLLDKPEGRVVEIEADYTCFTIPNEFVVGYGLDY
                     KENYRNLPYIGVLKEEVYSN"
     gene            complement(2539..3816)
                     /gene="tilS"
                     /locus_tag="VVR63_000766"
     CDS             complement(2539..3816)
                     /gene="tilS"
                     /locus_tag="VVR63_000766"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HEU6128803.1"
                     /translation="MREPDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQK
                     ELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDF
                     FQEVMKKTGATALVTAHHADDQVETILMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFL
                     HFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPELEKENPRFRDAILGIGNEILDYD
                     LAIAELSNNINVENLQQLFSYSESTQRVLLQTYLNRFPDLNLTKAQFAEVQQILKSKS
                     QYRHPIKNGYELIKEYQQFQICKISPQADEEEDELVLHYQNQVAYQGYLFSFGLPLEG
                     ELIQQIPVSRETSIHIRHRKTGDVLIQNGHRKKLRRLFIDLKIPMEKRNSALIIEQFG
                     EIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR"
     gene            complement(3813..5081)
                     /locus_tag="VVR63_000767"
     CDS             complement(3813..5081)
                     /locus_tag="VVR63_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A beta-lactamase-related serine hydrolase"
                     /protein_id="HEU6128804.1"
                     /translation="MRKFLIILLLPSFLTISKVVSTEKEVVYTSKEIYYLSQSDFSIY
                     FREKLSSPMVYGEVPVYANEDLVVESGKLTPKTSFQITEWRLNKQGIPVFKLSNHQFI
                     AADKRFLYDQSEVTPTIKKAWLESDFKLYNSPYDLKEVKSSLSAYSQVSIDKTMFVEG
                     REFLHIDQAGWVAKESTSEEDNRMSKVQEMLSEKYQKDSFSIYVKQLTTGKEAGINQD
                     EKMYAASVLKLSYLYYTQEKINEGLYQLDTTVKYVSAVNDFPGSYKPEGSGSLPKKED
                     NKEYSLKDLITKVSKESDNVAHNLLGYYISNQSDATFKSKMSAIMGDDWDPKEKLISS
                     KMAGKFMEAIYNQNGFVLESLTKTDFDSQRIAKGVSVKVAHKIGDADEFKHDTGVVYA
                     DSPFILSIFTKNSDYDTISKIAKDVYEVLK"
     gene            complement(5201..5569)
                     /locus_tag="VVR63_000768"
     CDS             complement(5201..5569)
                     /locus_tag="VVR63_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HEU6128805.1"
                     /translation="MSKNIVQLNNSFIQNEYQRRRYLMKERQKRNRFMGGVLILIMLL
                     FILPTFNLAQSYQQLLQRRQQLADLQTQYQTLSDEKDKETAFATKLKDEDYAAKYTRA
                     KYYYSKSREKVYTIPDLLQR"
     gene            complement(5562..5828)
                     /locus_tag="VVR63_000769"
     CDS             complement(5562..5828)
                     /locus_tag="VVR63_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HEU6128806.1"
                     /translation="MRLDKYLKVSRIIKRRTVAKEVADKGRIKVNGILAKSSTDLKVN
                     DQVEIRFGNKLLLVKVLEMKDSTKKEDAAGMYEIISETRVEENV"
     gene            complement(5886..9395)
                     /gene="mfd"
                     /locus_tag="VVR63_000770"
     CDS             complement(5886..9395)
                     /gene="mfd"
                     /locus_tag="VVR63_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000258090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HEU6128807.1"
                     /translation="MVTLLDLFSENDQIKKWHQNLTDKKRQLILGLSTSTKALAIASS
                     LEKEDRIVLLTSTYGEAEGLVSDLISILGEELVYPFLVDDAPMVEFLMSSQEKIISRV
                     EALRFLTDSSKKGILVCNIVASRLILPSPNAFKDSIVKISVGEEYDQHAFIHQLKENG
                     YRKVTQVQTQGEFSLRGDILDIFEISQLEPCRIEFFGDEIDGIRSFEVETQLSKENKT
                     ELTIFPASDMLLREKDYQRGQSALEKQISKTLSPILKSYLEEILSSFHQKQSHADSRK
                     FLSLCYDKTWTVFDYIEKDTPIFFDDYQKLMNQYEVFERDLAQYFTEELQNSKAFSDM
                     QYFSDIEQIYKKQSPVTFFSNLQKGLGNLKFDKIYQFNQYPMQEFFNQFSFLKEEIER
                     YKKMDYTIILQSSNSMGSKTLEDMLEEYQIKLDSRDKTNICKESVNLIEGNLRHGFHF
                     VDEKILLITEHEIFQKKLKRRFRRQHVSNAERLKDYNELEKGDYVVHHIHGIGQYLGI
                     ETIEIKGIHRDYVSVQYQNGDQISIPVEQIHLLSKYISSDGKAPKLNKLNDGHFKKAK
                     QKVKNQVEDIADDLIKLYSERSQLKGFAFSADDDDQDAFDDAFPYVETDDQLRSIEEI
                     KRDMQASQPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVVILVPTTVLAQQHYTNFK
                     ERFQNFAVNIDVLSRFRSKKEQTATLEKLKNGQVDILIGTHRVLSKDVVFADLGLMII
                     DEEQRFGVKHKETLKELKKQVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPV
                     QTYVLEKNDSVIRDAVLREMERGGQVYYLYNKVDTIVQKVSELQELIPEASIGYVHGR
                     MSEVQLENTLLDFIEGQYDILVTTTIIETGVDIPNANTLFIENADHMGLSTLYQLRGR
                     VGRSNRIAYAYLMYRPEKSISEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNLLG
                     KSQSGFIDSVGFELYSQLLEEAIAKRNGNANANTRTKGNAELILQIDAYLPDTYISDQ
                     RHKIEIYKKIRQIDNRVNYEELQEELIDRFGEYPDVVAYLLEIGLVKSYLDKVFVQRV
                     ERKDNKITIQFEKVTQRLFLAQDYFKALSVTNLKAGIAENKGLMELVFDVQNKKDYEI
                     LEGLLIFGESLLEIKEFKEENSI"
     gene            complement(9396..9965)
                     /locus_tag="VVR63_000771"
     CDS             complement(9396..9965)
                     /locus_tag="VVR63_000771"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HEU6128808.1"
                     /translation="MTKLLVGLGNPGDKYFETKHNVGFMLIDQLAKKQNVTFTHDKIF
                     QADLASFFLNGEKIYLVKPTTFMNESGKAVHALLTYYGLDIDDLLIIYDDLDMEVGKI
                     RLRAKGSAGGHNGIKSIIQHIGTQVFNRVKIGIGRPKNGMSVVHHVLSKFDRDDYIGI
                     LQSIDKVDDSVNYYLQEKNFEKTMQRYNG"
     gene            complement(10037..11152)
                     /gene="ychF"
                     /locus_tag="VVR63_000772"
     CDS             complement(10037..11152)
                     /gene="ychF"
                     /locus_tag="VVR63_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HEU6128809.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTEMITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESVNKRYARVEKMARTQKD
                     KESVAEFNVLQKIKPVLEDGKSARTIEFTDEEQKVVKGLFLLTTKPVLYVANVDEDVV
                     SEPDSIDYVKQIREFAATENAEVVVISARAEEEISELDDEDKKEFLEAIGLTESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGMKAPQAAGIIHSDFEKGFIRAVTMSYED
                     LVKYGSEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV"
     gene            complement(11236..11430)
                     /locus_tag="VVR63_000773"
     CDS             complement(11236..11430)
                     /locus_tag="VVR63_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HEU6128810.1"
                     /translation="MYQVGNFVEMKKSHACTIKSTGKKANRWEITRVGADIKIKCSNC
                     EHVVMMGRYDFERKMNKIID"
     gene            complement(11495..12631)
                     /gene="dnaN"
                     /locus_tag="VVR63_000774"
     CDS             complement(11495..12631)
                     /gene="dnaN"
                     /locus_tag="VVR63_000774"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HEU6128811.1"
                     /translation="MIHFSINKNLFLQALNTTKRAISSKNAIPILSTVKIDVTNEGIT
                     LIGSNGQISIENFISQKNEDAGLLITSLGSILLEASFFINVVSSLPDVTLDFKEIEQN
                     QIVLTSGKSEITLKGKDSEQYPRIQEISASTPLILETKLLKKIINETAFAASTQESRP
                     ILTGVHFVLSQHKELKTVATDSHRLSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDD
                     IETVEIFFANNQILFRSENISFYTRLLEGNYPDTDRLIPTDFNTTITFNVVNLRQSME
                     RARLLSSATQNGTVKLEIKDGVVSAHVHSPEVGKVNEEIDTDQVTGEDLTISFNPTYL
                     IDSLKALNSEKVTISFISAVRPFTLVPADTDEDFMQLITPVRTN"
     gene            complement(12790..14151)
                     /gene="dnaA"
                     /locus_tag="VVR63_000775"
     CDS             complement(12790..14151)
                     /gene="dnaA"
                     /locus_tag="VVR63_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HEU6128812.1"
                     /translation="MKEKQFWNRILEFAQERLTRSMYDFYAIQAELIKVEENVATIFL
                     PRSEMEMVWEKQLKDIIVVAGFEIYDAEITPHYIFTKPQDTTSSQVEEATNLTLYDYS
                     PKLVSIPYSDTGLKEKYTFDNFIQGDGNVWAVSAALAVSEDLALTYNPLFIYGGPGLG
                     KTHLLNAIGNEILKNIPNARVKYIPAESFINDFLDHLRLGEMEKFKKTYRSLDLLLID
                     DIQSLSGKKVATQEEFFNTFNALHDKQKQIVLTSDRSPKHLEGLEERLVTRFSWGLTQ
                     TITPPDFETRIAILQSKTEHLGYNFQSDTLEYLAGQFDSNVRDLEGAINDITLIARVK
                     KIKDITIDIAAEAIRARKQDVSQMLVIPIDKIQTEVGNFYGVSIKEMKGSRRLQNIVL
                     ARQVAMYLSRELTDNSLPKIGKEFGGKDHTTVIHAHAKIKSLIDQDDNLRLEIESIKK
                     KIK"
     gene            complement(14364..15122)
                     /locus_tag="VVR63_000776"
     CDS             complement(14364..15122)
                     /locus_tag="VVR63_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HEU6128813.1"
                     /translation="MEKFEMISITDIQKNPYQPRKEFDREKLDELAQSIKENGVIQPI
                     IVRQSPVIGYEILAGERRYRASLLAGLRSIPAVVKQISDQEMMVQSIIENLQRENLNP
                     IEEARAYESLVEKGFTHAEIADKMGKSRPYISNSIRLLSLPEQILSEVENGKLSQAHA
                     RSLVGLNKEQQDYFFQRIIEEDISVRKLETLLTEKKQKKQQKTNHFIQNEEKQLRKLL
                     GLDVEIKLSKKDSGKIIISFSNQEEYSRIINSLK"
     gene            complement(15180..16361)
                     /locus_tag="VVR63_000777"
     CDS             complement(15180..16361)
                     /locus_tag="VVR63_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HEU6128814.1"
                     /translation="MKHLKTFYKKWFQLLVVIVISFFSGALGSFSITQLTQKSSVNNS
                     NNNSTITQTAYKNENSTTQAVNKVKDAVVSVITYSANRQNSVFGNDDTDTDSQRISSE
                     GSGVIYKKNDKEAYIVTNNHVINGASKVDIRLSDGTKVPGEIVGADTFSDIAVVKISS
                     EKVTTVAEFGDSSKLTVGETAIAIGSPLGSEYANTVTQGIVSSLNRNVSLKSEDGQAI
                     STKAIQTDTAINPGNSGGPLINIQGQVIGITSSKIATNGGTSVEGLGFAIPANDAINI
                     IEQLEKNGKVTRPALGIQMVNLSNVSTSDIRRLNIPSNVTSGVVVRSVQSNMPANGHL
                     EKYDVITKVDDKEIASSTDLQSALYNHSIGDTIKITYYRNGKEETTSIKLNKSSGDLE
                     S"
     gene            16544..17023
                     /gene="rlmH"
                     /locus_tag="VVR63_000778"
     CDS             16544..17023
                     /gene="rlmH"
                     /locus_tag="VVR63_000778"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HEU6128815.1"
                     /translation="MKIKVVTVGKLKEKYLKDGIAEYSKRISRFAKFEMIELSDEKTP
                     DKASESENQKILEIEGQRILSKIADRDFVIVLAIEGKTFFSEEFSKQLEETSIKGFST
                     LTFIIGGSLGLSSSVKNRANLSVSFGRLTLPHQLMRLVLVEQIYRAFTIQQGFPYHK"
     gene            17067..17140
                     /locus_tag="VVR63_000779"
     tRNA            17067..17140
                     /locus_tag="VVR63_000779"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:17101..17103,aa:Arg,seq:tct)
     gene            17305..17430
                     /gene="comC"
                     /locus_tag="VVR63_000780"
     CDS             17305..17430
                     /gene="comC"
                     /locus_tag="VVR63_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence-stimulating peptide ComC"
                     /protein_id="HEU6128816.1"
                     /translation="MKNTVKLEQFVALKEKDLQNIKGGEMRISRIILDFLFLRKK"
     gene            17451..18776
                     /locus_tag="VVR63_000781"
     CDS             17451..18776
                     /locus_tag="VVR63_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000362880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU6128817.1"
                     /translation="MDLLGFGTVIVHFLIISHSYRLICKGRINRKELYIFGAYTLLTE
                     IVLEFSFYLLYLDKIGIERFLFPLGLYSYFRWMKQYERDRGLFLSLLLSLLYESTHNF
                     LSVTFSSITGDNFVLQYHFPFFFVVTVLTYFVTLKIIYYFHLELAYFDKDYLYPFLKK
                     VFFALLLLHIVSFVSDMVSTIKHLNSFGSILSSIVFISLLLTFFAMNSHKVQMEKEIA
                     LKQKKFEQKHLQNYTDEIVGLYNEIRGFRHDYAGMLVSMQMAIDSGNLQEIDRIYNEV
                     LVKANHKLRSDKYTYFDLNNIEDSALRSLVAQSIVYARNNGVEFTLEVKDTITKLPIE
                     LLDLVRIMSVLLNNAVEGSADSYKKQMEVAVIKMETETVMVIQNSCKMTMTPSGDLFA
                     LGFSTKGRNRGVGLNNVKELLDKYNNIILETEMEGSTFRQIIRFKREFE"
     gene            18773..19525
                     /locus_tag="VVR63_000782"
     CDS             18773..19525
                     /locus_tag="VVR63_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU6128818.1"
                     /translation="MKVLILEDVIEHQVRLERILDEISKESNIPISYKTTGKVREFEE
                     YIENDEVNQLYFLDIDIHGIEKKGFEVAQLIRHYNPYAIIVFITSRSEFATLTYKYQV
                     SALDFVDKDINDEMFKKRIEQNIFYTKSMLLENEDVVDYFDYNYKGNDLKIPYHDILY
                     IETTGVSHKLRIIGKNFAKEFYGTMTDIQEKDKHTQRFYSPHKSFLVNIGNIREIDRK
                     NLEIVFYEDHRCPISRLKIRKLKDILEKKSQK"
     gene            19577..19648
                     /locus_tag="VVR63_000783"
     tRNA            19577..19648
                     /locus_tag="VVR63_000783"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19610..19612,aa:Glu,seq:ttc)
     gene            19654..19727
                     /locus_tag="VVR63_000784"
     tRNA            19654..19727
                     /locus_tag="VVR63_000784"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19688..19690,aa:Asn,seq:gtt)
     gene            complement(19768..20310)
                     /locus_tag="VVR63_000785"
     CDS             complement(19768..20310)
                     /locus_tag="VVR63_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HEU6128819.1"
                     /translation="MQESNKRLKTKRTIENAMVQLLMEQPFDKISTVKLVEKAGISRS
                     SFYTHYKDKYDMIEHYQSKLFHTFEYIFQKHAHHKRDAILEVFEYLESEPLLAALLSE
                     NGTKEIQNFLRNKLHIMLSTDLQKRFMQLNLNTTELEYSSIYLTHALFGVCQTWIAHG
                     KKESSQEITDFLMKMLGDTN"
     gene            20489..21256
                     /locus_tag="VVR63_000786"
     CDS             20489..21256
                     /locus_tag="VVR63_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
                     /protein_id="HEU6128820.1"
                     /translation="MIGISLIPALYNIIFLSSMWDPYGQLSDLPVAVVNNDKEASYNG
                     NTMAIGKDMVSNLKENKTLDFHFVDEEEGKKGLEDGDYYMVVTLPSDLSEKTTTLSNL
                     QSTAAYQSLTSEQQTEISDSVSQNSTDSIQSAQSIVALVQGLQGSLENLQNQSSNLST
                     LKNQANQVLPITSTSLIGLSSGLTEIQGDVTSKLVPASQSIASGVNAYTTGVDKVSQG
                     ASQLSEKNATLTGSLDKLVSGSNTLTQKSSRLTAGVG"
     gene            21260..21616
                     /locus_tag="VVR63_000787"
                     /pseudo
     CDS             21260..21616
                     /locus_tag="VVR63_000787"
                     /inference="COORDINATES: protein motif:HMM:TIGR03057.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            21706..22020
                     /locus_tag="VVR63_000788"
     CDS             21706..22020
                     /locus_tag="VVR63_000788"
                     /inference="COORDINATES: protein motif:HMM:TIGR03062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
                     /protein_id="HEU6128821.1"
                     /translation="MAGILVYGGVQLIGLTANHEMRIFILIILTSLVFMSMVTTLATW
                     NSRIGAFFSLILLLLQLASSAGTYPLALTNDFFRSINPWLPMSYSVSGLRQTISINKS
                     FS"
     gene            complement(22121..24673)
                     /locus_tag="VVR63_000789"
     CDS             complement(22121..24673)
                     /locus_tag="VVR63_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HEU6128822.1"
                     /translation="MKSFLKTYRTYFISFIIPVVIMSGVYLSQGIYWNSDNSPLLGDG
                     FHQYVIFDVALRNILHGNSSLFYTFTSGLGLNFYALSSYYLGSFLAPLVYFFDLTNMP
                     DAVYLTTLLKFGLIGLSTFFSLNKLFQSIPQTLKLALSTSYALMSFTVSQLEIKTWLD
                     VFILIPLIITGLHLLITEKKLLLYFTSLSILFIQNYYFGYMTVLFLIFWYLCQISWDF
                     KTRKSSVLDFIVISFLAGMASLIMTIPTLFDLQTHGEKLTEVTKFQTESSWYLDLFAK
                     QFIGSFDTTKYGAIPMIFVGLFPFILTILFFTLKSIKFHVKLIYVIFFAFLIASFYIE
                     ALDLFWQGMHTPNMFLHRYAWIFSTLLIYTAAEVLKRLKELKVWNFLVSLFLVVAGFL
                     ATIYLKSHYSFLTDLNILLTLEFLVVYSLLLLAVIKKFIFVNLFAILISLFILVEMSL
                     NASSQMDGIAKEWGFASRSAYSRDILAMESFSTYIGNQFTRTEKLQTQTGNDSMKFNY
                     NGISQFSSVRNRSSSSTLDKLGFKSSGTNLNLRYANNSILADSLFGIQYNISDSPIDK
                     YGFKDIYQKDNLTLYENQYSLPIAVASQSVYNDVKFNEHTLDNQASFLNQLANVNFDY
                     FSPIPYEKTEKIENTNDLISVTSSSNEDAAIQYQIEVPENSQVYLSFINLHFSNDKQK
                     KVDILVNGEKKTFTTDNVFSFFNLGYTKEKKTFNINVSFPGNSQVSFESPTFYRLDTK
                     TFTEAIQKIKEQPVTVSTSKNKVFATYDVQQDTSIFFTIPYDKGWSAYQDGKKIEIKQ
                     AQTGFMKVDIPKGKGTITLSFIPNGFITGAICSFTSLLLFGIYNHRRKSSKA"
     gene            complement(24735..26357)
                     /locus_tag="VVR63_000790"
     CDS             complement(24735..26357)
                     /locus_tag="VVR63_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU6128823.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTEGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEDERAIDVVIMGNEKLYSIMKEKDAI
                     YMKEDFSDEDGVRAAELEGEFAELGGWEAESEASQLLQNLNIPEELHYQNMSELANGE
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSITWLEDFLIDFDNTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWKESSELAAKLLADRNAKAEEKIKQLQEFVARFSANA
                     SKSRQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREIGNDLLTVENLTVKIDGETI
                     LDNISFILRPDDKTALIGQNDIQTTALIRAIMGDIDYEGTVKWGVTTSQSYLPKDNSA
                     DFAGGESILDWLRQFASKEDDDNTFLRGFLGRMLFSGDEVNKPVNVLSGGEKVRVMLS
                     KLMLLKSNVLVLDDPTNHLDLESISSLNDGLKNFKESIIFASHDHEFIQTLANHIIVL
                     SKNGVIDRIDETYDEFLENAEVQAKVKELWKD"
     gene            26563..27588
                     /gene="trpS"
                     /locus_tag="VVR63_000791"
     CDS             26563..27588
                     /gene="trpS"
                     /locus_tag="VVR63_000791"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HEU6128824.1"
                     /translation="MTKPIILTGDRPTGKLHIGHYVGSLKNRVLLQEEDKYDMFVFLA
                     DQQALTDHAKDPQTIVESIGNVALDYLAVGLDPNKSTIFIQSQIPELAELSMYYMNLV
                     SLARLERNPTVKTEISQKGFGESIPTGFLVYPIAQAADITAFKANYVPVGTDQKPMIE
                     QTREIVRSFNNAYNCDVLVEPEGIYPENERAGRLPGLDGNAKMSKSLNNGIYLADDAD
                     TLRKKVMSMYTDPDHIRVEDPGKIEGNMVFHYLDVFGRPEDAQEIADMKERYQRGGLG
                     DVKTKRYLLEILERELGPIRERRIEFAKDMGEVYNMIQKGSERAREVAGQTLSEVKGA
                     MGLHYFN"
     gene            27740..29218
                     /gene="guaB"
                     /locus_tag="VVR63_000792"
     CDS             27740..29218
                     /gene="guaB"
                     /locus_tag="VVR63_000792"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HEU6128825.1"
                     /translation="MSNWDTKFLKKGFTFDDVLLIPAESHVLPNDADLTTKLADNLTL
                     NIPIITAAMDTVTESQMAIAIARAGGLGVIHKNMSIAQQADEVRKVKRSENGVIIDPF
                     FLTPEHTIAEADELMGRYRISGVPVVETLENRKLVGILTNRDLRFISDYNQPISNHMT
                     SENLVTAPVGTDLATAESILQEHRIEKLPLVDEEGSLSGLITIKDIEKVIEFPNAAKD
                     EFGRLLVAGAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDR
                     TLIAGNIATAEGARALYEAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIFQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAAADIVFQMIGGIRSGMGY
                     CGAANLKELHDNAQFIEMSGAGLKESHPHDVQITNEAPNYSM"
     gene            complement(29270..30367)
                     /gene="recF"
                     /locus_tag="VVR63_000793"
     CDS             complement(29270..30367)
                     /gene="recF"
                     /locus_tag="VVR63_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HEU6128826.1"
                     /translation="MWLQHLSLKTFRNYKETKIDFNPKLNVFLGRNAQGKTNMLEAIY
                     FLALTRSHRTRTDKNLIHFDEEQLHLSGLVQKKTGSIPLEIELTQKGRVTKVNHLKQA
                     RLSDYVGHMNVVLFAPEDLQLIKGAPSIRRKFIDMELGQIKPIYLSDLTNYNHILKQR
                     NTYLKSDQKIDETFLSVLDDQLVDYGCRVMNHRLDFIKKLESFGRKKHFELSNQIEEL
                     SISYQSSVNITDKQNLSESFKIALEKSRSRDLFKKNTGVGPHRDDISFYINGMDASFG
                     SQGQHRSLVLSIKLAEIELMESITTESPILLLDDVMSELDNTRQLKLLETISQSIQTF
                     ITTTSLDHLQNLPENLSIFTIQDGKASVNGN"
     gene            complement(30370..30738)
                     /gene="yaaA"
                     /locus_tag="VVR63_000794"
     CDS             complement(30370..30738)
                     /gene="yaaA"
                     /locus_tag="VVR63_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HEU6128827.1"
                     /translation="MEYKLFEEFITLQALLKELGITHSGGAIKSFLSEHSVYFNRELE
                     SRRGKKLRIGDKVDIPDMNIDILLTQPTSEEQDEYQADKVEKERIAKLVKKMNKGVKK
                     DKSKPASSPKSQQAPRFPGR"
     gene            30897..32147
                     /locus_tag="VVR63_000795"
     CDS             30897..32147
                     /locus_tag="VVR63_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEU6128828.1"
                     /translation="MELVHGISTHFIQSKKFKTNKITVRFTAPLSLDTIAGHMLSASM
                     LETANQMYPTSQDLRRHLASLYGTDMSTNCFRRGQSHIIELTFTYVRDEFLSRKNVLT
                     SQILELVKETLFSPVVVDNGFDPALFEIEKKQLLASLAADMDDSFYFAHKELDKLFFH
                     DERLQLEYSDLRNRILAETPQSSYSCFQEFLANDRIDFFFLGDFNEVEIQNVLESFGF
                     KGRKGDVKVQYCQPYSNILQEGMVRKNVGQSILELGYHYCSKYGDEQHLPMIVMNGLL
                     GGFAHSKLFTNVRENAGLAYTISSELDLFSGFLRMYAGINRENRNQARKMMNNQLLDL
                     KKGYFTEFELNQTKEMIRWSLLLSQDNQSSLIERAYQNALFGKSSADFKSWIAKLEQI
                     DKDAICRVANNVKLQAIYFMEGIE"
     gene            32144..33427
                     /locus_tag="VVR63_000796"
     CDS             32144..33427
                     /locus_tag="VVR63_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEU6128829.1"
                     /translation="MTKVVFEEKYYPAVKEKVYRTRLANGLTVALLPKKEFKEVYGSV
                     TVQFGSVDTFVTEVDGDVKQYPGGIAHFLEHKLFEREDSSDLMSAFTSLGADSNAFTS
                     FTKTNYLFSATDYFLENLDLLDELVTSAHFTEASILTEQDIIQQEREMYQDDPDSCLF
                     FSTLANLYPGTPLATDIVGSEESISQINLTNLQENFTKFYKPVNMSLFLVGNFDVERV
                     QDYFESKELKDSDFQEVAREKLFLQPVKPTDSMRMEVSSPKLAIGVRGKREVSEADCY
                     RHHILLKLLFAMMFGWTSDRFQKCYESGKIDASLSLEVEVTSRFHFVMLTMDTKEPVA
                     LSHQFRKAIRNFTKDLDITEEHLDIIKREMFGEFFSSMNSLEFIATQYDAFENGETIF
                     DLPKILQEITLEDVLDAGHHLIDDGDIVDFTIFPS"
     gene            33469..34290
                     /locus_tag="VVR63_000797"
     CDS             33469..34290
                     /locus_tag="VVR63_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU6128830.1"
                     /translation="MRKKTIGEVLRLARINQGLSLDELQKKTEIQLDMLEAMEADDFD
                     QLPSPFYTRSFLKKYAWAVELDDQIVLDAYDSGSMITYEEVDVDEDELTGRRRSSKKK
                     KKKTSFLPLFYFILFALSILIFVTYYVWNYIQTQPEEPSLSNYSVVQSTSSTSSVPHS
                     SSSSSSSIESAISVSGEGNHVEIAYKTSKETVKLQLAVSDVTSWVSVSESELEGGVTL
                     SPKKKSAEATVATKSPVTITLGVVKGVDLTVDNQTVDLSKLTAQTGQITVTFTKN"
     gene            34301..34846
                     /gene="pgsA"
                     /locus_tag="VVR63_000798"
     CDS             34301..34846
                     /gene="pgsA"
                     /locus_tag="VVR63_000798"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HEU6128831.1"
                     /translation="MKKEQIPNLLTIGRILFIPIFIFILTIGNSIESHIVAAIIFAVA
                     SITDYLDGYLARKWNVVSNFGKFADPMADKLLVMSAFIMLIELGMAPAWIVAVIICRE
                     LAVTGLRLLLVETGGTILAAAMPGKIKTFSQMFAIIFLLLHWTLLGQVLLYVALFFTI
                     YSGYDYFKGSAYVFKGTFGSK"
     gene            34843..35670
                     /locus_tag="VVR63_000799"
     CDS             34843..35670
                     /locus_tag="VVR63_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEU6128832.1"
                     /translation="MKSIIDVKNLSFRYKENQNYYDVKDITFHVKRGEWLSIVGHNGS
                     GKSTTVRLIDGLLEAESGEIVIDGQRLTEENVWNIRRQIGMVFQNPDNQFVGATVEDD
                     VAFGLENQGLSRQEMKKRVEEALALVGMLDFKKREPARLSGGQKQRVAIAGVVALRPA
                     ILILDEATSMLDPEGRRELIGTVKGIRKDYDMTVISITHDLEEVAMSDRVLVMKKGEI
                     ESTSSPRELFSRNDLDQIGLDDPFANQLKKSLSQNGYDLPENYLTESELEDKLWELL"
     gene            35655..36494
                     /locus_tag="VVR63_000800"
     CDS             35655..36494
                     /locus_tag="VVR63_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEU6128833.1"
                     /translation="MGIALENVNFTYQEGTPLASAALSDVSLTIEDGSYTALIGHTGS
                     GKSTILQLLNGLLVPSQGSVRVFDTLITSTSKNKDIRQIRKQVGLVFQFAENQIFEET
                     VLKDVAFGPQNFGVSEEDAVKTAREKLALVGIDESLFDRSPFELSGGQMRRVAIAGIL
                     AMEPAILVLDEPTAGLDPLGRKELMTLFKKLHQSGMTIVLVTHLMDDVAEYANQVYVM
                     EKGRLVKGGKPSDVFQDVVFMEEVQLGVPKITAFCKRLADRGVSFKRLPIKIEEFKES
                     LNG"
     gene            36487..37281
                     /locus_tag="VVR63_000801"
     CDS             36487..37281
                     /locus_tag="VVR63_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEU6128834.1"
                     /translation="MDSMILGRYIPGDSIVHRLDPRSKLLAMMLLILIVFWANNPLTN
                     LILFIATGIFIALSGVSLSFFIQGLKSMFFLIAFTTIFQLFFISNGNVLFEFSFVRIT
                     DYALQQAGIIFCRFVLIIFFSTLLTLTTMPLSLASAVEALLAPLKRVKVPVHEIGLML
                     SMSLRFVPTLMDDTTRIMNAQKARGVDFGEGSIVQKVKAMIPILIPLFATSLKRADSL
                     AIAMEARGYQGGKGRSQYRQLKWTLKDTLTILVILVLGCCLFFLKS"
     gene            37340..38158
                     /gene="mreC"
                     /locus_tag="VVR63_000802"
     CDS             37340..38158
                     /gene="mreC"
                     /locus_tag="VVR63_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HEU6128835.1"
                     /translation="MNRFKKSKYVIIVFVTVLLVSALLATTYSSTIVTKLGDGISLVD
                     RVVQKPFQWFDSVKSDLAHLTRTYNENESLKKQLYQLEVKSNEVESLKTENEQLRQLL
                     DMKSKLQATKTLAADVIMRSPVSWKQELTLDAGRSKGASENMLAIANGGLIGSVSKVE
                     ENSTIVNLLTNTENADKISVKIQHGSTTIYGIIIGYDKENDVLKISQLNSNSDISAGD
                     KVTTGGLGNFNVADIPVGEVVATTHSTDYLTREVTVKLSADTHNVDVIELVGNS"
     gene            38158..38652
                     /gene="mreD"
                     /locus_tag="VVR63_000803"
     CDS             38158..38652
                     /gene="mreD"
                     /locus_tag="VVR63_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HEU6128836.1"
                     /translation="MRQLKRVGVFLLLPFFVLIDAHISQLLGSFFPHVHLASHFLFLF
                     LLFETIEVSEYLYLVYCFVIGLVYDVYFFHLIGITTLLFILLGAFLHKLNSVILLNRW
                     TRMLAMIVLTFLFEMGSYLLAFMVGLTVDSMSIFIVYSLVPTMILNFLWITVFQFIFE
                     KYYL"
     gene            38746..39924
                     /locus_tag="VVR63_000804"
     CDS             38746..39924
                     /locus_tag="VVR63_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEU6128837.1"
                     /translation="MKKKILASLLLSTVMVSQVAVLTTAHAETTDDKIAAQDNKISNL
                     TAQQQEAQKQVDQIQEQVSAIQAEQSNLQAENDRLQAESKKLEGEITELSKNIVSRNQ
                     SLEKQARSAQTNGAVTSYINTIVNSKSITEAISRVAAMSEIVSANNKMLEQQKADKKA
                     ISEKQVANNDAINTVIANQQKLADDAQALTTKQAELKAAELSLAAEKATAEGEKASLL
                     EQKAAAEAEARAAAVAEAAYKEKRASQQQSVLASANTNLTAQVQAVSESAAAPVRAKV
                     RPTYSTNASSYPIGECTWGVKTLAPWAGDYWGNGAQWATSAAAAGFRTGSTPQVGAIA
                     CWNDGGYGHVAVVTAVESTTRIQVSESNYAGNRTIGNHRGWFNPTTTSEGFVTYIYAD
                     "
     gene            40148..40927
                     /gene="rpsB"
                     /locus_tag="VVR63_000805"
     CDS             40148..40927
                     /gene="rpsB"
                     /locus_tag="VVR63_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HEU6128838.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKYADQAYDFMRDAAANDAVVLFVGTKKQAADAVAEEAVRSGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEDGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNTDPDDIDVIIPANDDAIRAVKLITAKLA
                     DAIIEGRQGEDAVAVEAEFAASETQADSIEEIVEVVEGDNA"
     gene            41006..42046
                     /locus_tag="VVR63_000806"
     CDS             41006..42046
                     /locus_tag="VVR63_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HEU6128839.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDIEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVIEVNAETDFVAKNAQFVELVNTTAKVIAE
                     GKPANNEEALALIMPSGETLEAAYVSATATIGEKISFRRFALIEKTDAQHFGAYQHNG
                     GRIGVISVVEGGDEALAKQLSMHIAAMKPTVLSYKELDEQFVKDELAQLNHVIDQDNE
                     SRAMVNKPALPHLKYGSKAQLTDDVIAQAEADIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLESVNASVVEFARFEVGEGIEKAANDFEA
                     EVAATMAAALNN"
     gene            42292..42615
                     /gene="tnpB"
                     /locus_tag="VVR63_000807"
     CDS             42292..42615
                     /gene="tnpB"
                     /locus_tag="VVR63_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HEU6128840.1"
                     /translation="MMIQLSDLGQVHIVCGKTDMRQGIDSLAYVVKTHFELDSFSGQV
                     FLFCGERKDRFKALYWDGQGFWLLYKRFENGKLTWLSTEKDVKALAPEQVDWLMKGFS
                     ITPKI"
BASE COUNT        13391 a         7379 c         7888 g        14121 t
ORIGIN      
        1 ctccagcctc tctcagggtt atttttcgtc attcattttt gactttactt catcatagga
       61 tagtgcatga gattcctctt ctactgcttc aggcatcttt cctgtttcgt aaagagcttt
      121 aatttgtgta ctatccaatg tttcgtattt caataatgct tctgcaatta acttgtgagt
      181 ttcacgattt gactgaataa tttcagcagc tttatttcgt gcctcattta ataatgaacg
      241 aacctcttca tcaatttcat aagctgtttg ttctgaaatt gatttttgag gactctgtgc
      301 accaagcata gcatggtttc cttcatattg tactgggcca agtttttcac tcataccgta
      361 ctctgtaacc attgcacgtg ccatttgtgt cgcttgttca aagtcgtttg aagctcctgt
      421 agtttggaca ttaaagataa tttcttcagc tacacgtcca cccattaagc cagccaattg
      481 ctctttcata tcttctttag atagaagcat ttgatcctct ttaggaagtg caatcatgta
      541 tccgcctgca cggccgcgtg gtacaattgt aaccttatgg acaacgcgag cattcgacaa
      601 gactagacca acaatggtat gtcctgcctc atggtgagca accaattctc gttctttttg
      661 tgaaactgtc ttatctttct tagaaggtcc agcaataact ctatcttctg cttcatcaat
      721 atctgaagca tcaattatcg atttattgcg acgagcagca actaaagctg cttcattcaa
      781 gacattctct aaatcagcac caacaaagcc tggagtttgt tgagccacta atttcaaatc
      841 aacatcttct gctaaaggct tgttcttagc gtgaactttc aagattgctt cacgaccttt
      901 aacatcagga cggccaacca atacttttct atcaaaacgt cctggacgca aaagggcagg
      961 atcaagtaca tctgaacggt ttgtcgcagc gatgacgata atcccttcat ttccctcaaa
     1021 accatccatc tcaatcaaaa gttggttcaa ggtttgttca cgttcgtcat tacctccgcc
     1081 gagaccgact ccacgttgac gtccaacagc atcaatttca tcgataaaga tgatagctgg
     1141 tgctgctttt ttggcatcct caaaaagaga gcgaacacga ctagctccaa ctccgacaaa
     1201 catttctaca aagtcagaac ctgagatact aaagaatgga acacctgctt ctccagcgac
     1261 tgccttagca agcaaagtct tacctgtccc cggaggtccc tccaaaagaa cacctgctgg
     1321 aatacgggct ccaagttttg tgaatcgttt tggatctttt aagaactcaa caacttcaac
     1381 tagttcttgt ttttcttcct cagctccagc aacatctgaa aatcttactt taatatcttc
     1441 tttatttgct gctttagcct tactacgtcc aaaactcatt ggattacggc cattgcctcc
     1501 tcccatattt cccatcatag agaataggaa gaagaataga attccaaatg gcacaatgga
     1561 tacgagtaga ttaatccata taccacttga actttcatgc ttaacagtta cttctgcttt
     1621 atggtcagta gcaagttttt gcaattctga tacggtagta tctgcaggaa gaatagtgct
     1681 ggtaaatttc tctaccttag taacagatgg cgtgaaaaac tgaatacctg ttccttcttt
     1741 acttgtttta ggatttttat agacaccaga aacttcgata acactaccat ttggttggta
     1801 agttaattct tttacattac catcggtaat ttcttgtacc aactcagtat agttgatttg
     1861 ctgacttcct cctgagttat tcccagaata gaaatactgg aatcctgtca caaggaaaaa
     1921 gataaataat aaccatagaa aaggattttt aattaaacca ttattttgtt ttttcattaa
     1981 agattattct ttctaatttg aatacacttc ctctttcaat actccaatat aaggaagatt
     2041 acgataattt tctttgtagt ctaaaccata acctactaca aactcatttg ggatagtaaa
     2101 gcaggtatag tctgcctcaa tttctacaac acgtccttct ggtttatcca acaaggttgc
     2161 aattttaaca gaagctgctt ctctttcttt aaacatatct cgcaaattct tcaaagtttg
     2221 acctgtatca atgatatctt ctacaaatag aacatgtctt cctttgatat cttgagtcac
     2281 atcttgttta atattgataa caccactact tgctgttcca ccatggtagc tagaaaccat
     2341 catgaagtcc atttcaatat gtgtatcaat atgtttgacc aattcagcca taaaaggaat
     2401 agatcctttt aaaatcccaa ctaagattgg attttttcct gcatagtctt tagttaattg
     2461 agcacctagt tttttagctg cttctgtaat ttcatcgtgt gaaacgagga cttttttaat
     2521 atcgttttct aacatttttt acctatctat tttttctata taaagtacag tgttcattat
     2581 atcatttttc gtttttttac tcaaattatt ggtcgcaatt cccaaaattg agacaatttc
     2641 accaaattgc tcaataataa gagcagagtt tctcttttcc atagggattt tcaaatcaat
     2701 aaataaacgt ctgagttttt ttctatgccc attttgaatc aaaacatctc ctgtttttcg
     2761 atgacgaatg tgtatggatg tttcacgtga aacaggtatt tgttgaatta attcaccttc
     2821 taatggaagt ccaaaggaaa ataaatatcc ttgataagct acctgatttt gatagtgtaa
     2881 cacaagttca tcttcctctt catcagcctg cggactgatt ttacaaatct gaaactgttg
     2941 gtactctttt atcaattcat agccattttt aatcggatga cgatactggc ttttagattt
     3001 taaaatctgc tgaacttcag caaactgagc ttttgtaaga ttcaaatctg gaaaacgatt
     3061 cagataagtt tgaagtaaaa ctctttgtgt agactcagag taagaaaata actgctgtaa
     3121 attttccaca ttaatattgt tagataattc agctattgcc aaatcataat ctaaaatttc
     3181 attgccgatg cctaagattg catccctaaa tcgaggattt tctttttcca attctggtaa
     3241 gtaagaattt cgaatacgat ttcgaaaata atgattctcc tgatttgatg tatcttcaaa
     3301 gtgaaaaatt gatggaaagt cttttttctg aaaatgcaag aagggacgaa tgatttctat
     3361 ctctccgact acttgcttct ccttaattcc tgatagatag cgcaagcgag ttcctcgaat
     3421 caagcgcatc aaaatcgttt ccacctgatc atcagcatgg tgggcagtga ctaaagctgt
     3481 cgcacctgtc tttttcatga cctcttgaaa aaaatcataa cgaaaatttc gtgcacgcgc
     3541 ttctgaaaat tctcctgaaa aattgctgat ataaatagga agctctgctt cagcagccaa
     3601 cttccttaat tccttttctt cccaatctga ttcaattctc tgcttatgat tcacatgagc
     3661 tagaatcaat tcaatctcta actctttttg ataagtagac aataccttaa atagaaacat
     3721 ggaatctaat ccaccagaaa gagctagaac cgccttagca tgctttttga aatatccctt
     3781 cttgagaaaa tgatttaaaa aatctggttc cctcatttta gaacctcata aacatccttg
     3841 gctatcttag aaatcgtatc ataatcagaa ttcttagtga aaatagaaag aataaatgga
     3901 gaatctgcat agacaacacc cgtatcatgc ttaaattcat ccgcatctcc aattttatga
     3961 gctactttaa cagaaacacc tttggcaatt cgctgactat caaaatctgt tttagtcaaa
     4021 gactctagca caaatccatt ttgattataa atagcttcca taaacttccc ggccatctta
     4081 gaagaaatca atttttcttt tggatcccaa tcatctccca taatggcaga catcttggat
     4141 ttgaatgtgg catcagattg gtttgaaatg taatatccca atagattatg agctacatta
     4201 tcagattctt ttgatacttt cgtaattaaa tcctttaaag aatattcttt attatcttct
     4261 tttttaggaa gactaccact tccctctggt ttataagaac ctggaaaatc attgactgca
     4321 gatacgtatt ttacagtcgt atctaactga taaagaccct catttatttt ttcttgcgta
     4381 taatagagat aggagagttt caaaacgctg gctgcataca tcttttcatc ttgattgata
     4441 ccagcttctt ttccagtagt cagttgctta acataaatag agaaagaatc tttctgatat
     4501 ttttcagata acatttcttg aactttactc atccgattat cttcttcaga agttgattct
     4561 ttagctaccc atccagcctg atcaatatgt agaaattctc ttccttctac aaacatggtc
     4621 ttgtcgattg atacttgcga ataagctgat aaggatgatt tcacttcttt taaatcataa
     4681 ggactattgt acagtttaaa gtcagattct aaccatgctt tttttattgt tggagttacc
     4741 tctgattgat catataaaaa tcgtttgtcc gcagctataa attgatgatt tgatagctta
     4801 aatactggaa ttccttgttt atttaagcgc cactcggtta tttgaaaact tgttttggga
     4861 gtcaatttcc cagattccac tactaaatct tcattcgcat aaacaggaac ctctccataa
     4921 accatgggag aacttaattt ttctctaaaa taaatactaa agtcagattg tgaaaggtaa
     4981 taaatttctt tcgaagtata gacgacttct ttttctgtgc taacgacttt tgaaatggtc
     5041 aaaaaacttg gtagcaacaa aataattaag aatttacgca ttcttccttt ccttttcttc
     5101 ttgtaaacgc aataattgat ttttatcagc caattcttcc agcttttcat ctgacaaact
     5161 caaaaattgc tctattacgt ctaataaatt ttccatttta tcacctttga agcaagtcag
     5221 gaatcgtata aactttttcc ctcgacttag aataatagta cttcgctcgt gtatatttag
     5281 cagcataatc ttcatctttc aacttggtag caaatgctgt ctccttatcc ttttcatcac
     5341 tcaaagtttg atactgagtt tgcaagtctg ctaattgctg acgtctttgg agtaattgct
     5401 gataactctg cgctaaatta aaagttggca agataaataa tagcataatc aaaatcaata
     5461 cccctcccat aaaacgattc cgtttttgtc gttctttcat caggtagcga cgacgttggt
     5521 attcattttg aataaaagaa ttattcaatt gtacaatatt tttagacatt ttcttctacc
     5581 cgtgtttcac tgataatttc atacattcct gctgcatctt ctttttttgt actatctttc
     5641 atctctagta cttttacaag cagcaactta ttgccaaagc gaatttcaac ttggtcatta
     5701 actttcaagt ccgttgaact tttggccaag attccattaa ccttgattct acctttatct
     5761 gctacttcct ttgcgactgt acgacgcttg ataattcgcg atacttttaa atatttatct
     5821 aatctcatcc ttattacctc aatttattat tgtaccattt ttatctattt tatagaagaa
     5881 aaatatcaaa tggaattttc ttccttaaac tcttttatct ctaataaact ttctccaaaa
     5941 atcagcagac cttctaaaat ttcataatct ttcttatttt ggacatcaaa tacaagctcc
     6001 attaatccct tattctcagc gatgcctgct tttaagttcg ttacggataa agctttaaaa
     6061 taatcttgag ctaaaaacag ccgttgagtg actttttcaa attgaattgt aattttatta
     6121 tcttttcttt ccacacgttg aacaaagacc ttgtccaagt atgatttaac caaaccaatc
     6181 tctaaaagat aggctactac atctgggtat tctccaaaac ggtctatcaa ctcctcttgt
     6241 aactcttcat aattgacacg gttgtcaatt tgacgaattt tcttgtaaat ttcaatctta
     6301 tgtcgttgat cagaaatata agtatcagga agataggcat caatttgcaa aatcaactca
     6361 gcattccctt tggttcttgt gttagcgtta gcattaccgt ttcgtttagc aatagcttcc
     6421 tctaataact gcgaatacaa ttcaaaacca acagaatcaa tgaaaccaga ctgggatttt
     6481 cctaaaagat ttcctgctcc acgaatcgaa agatctcgca ttgcaatctt aaagccagag
     6541 cccaattctg taaatccttt aatcgcttct aatctctttt cagagacttc actgattgat
     6601 ttttctggac gatacatgag ataagcataa gcaatacgat tactacgacc gactcttcct
     6661 cttaactgat ataaggttga caagcccata tggtccgcat tttcaataaa taaagtatta
     6721 gcatttggaa tgtccacccc tgtctcaata atagtagtcg tcaccaagat atcgtattgt
     6781 ccctcaataa agtctaatag agtattttcc aactggactt cactcattcg accatgaaca
     6841 tatccaatcg aagcctccgg aatcaactcc tgtaattctg aaaccttctg aacaattgtg
     6901 tcaactttgt tgtaaagata ataaacttga cctccacgct ccatttcacg caagacagca
     6961 tcacgaatga cactatcatt cttttccaaa acataggtct gaacaggata gcgattagtc
     7021 ggcggagttt caataacaga taaatctctg attcccagca tagacatatg gagggtacga
     7081 gggattggcg tagcggtcaa ggttaggaca tccacttgtt tcttcagttc tttcaaagtt
     7141 tccttatgct tgacaccaaa tcgctgttcc tcatcaataa tcatcaagcc caaatcagca
     7201 aacacaacat cttttgacaa aacacgatgt gttccaatca aaatatcgac ttgaccgttt
     7261 ttcaattttt caagtgttgc agtctgctct tttttacttc taaagcgact caacacatca
     7321 atattaactg caaaattttg gaatcgttcc ttaaaattcg tatagtgctg ttgcgctaaa
     7381 accgtcgtcg gaactagaat gacaacctgt ttgtgatcat tgactgcttt aaaggctgca
     7441 cgcatagcaa cttcagtctt tccaaaacca acatccccaa ctaaaagtcg atccattggc
     7501 tgagaagcct gcatatccct cttgatttcc tcaatactac gaagttgatc atccgtttca
     7561 acataaggga aagcatcatc aaaggcatct tgatcatcat catcagctga gaaagcaaaa
     7621 cccttcaact gactacgttc agagtagagt ttgattaaat catcagctat atcctctacc
     7681 tggttcttaa ccttttgctt ggccttttta aaatgaccgt catttaattt attgagtttt
     7741 ggagctttac catcacttga aatatatttg gacagtagat gaatctgttc cacggggata
     7801 gaaatttgat caccattttg gtattggaca ctgacataat cgcgatgaat tcccttgatt
     7861 tcaatggttt caattcctag atattgacca atcccatgga tatgatggac aacatagtcc
     7921 cctttttcaa gttcattgta atcttttaat ctctctgcat ttgaaacatg ttgtcttcga
     7981 aaacgacgct ttaatttctt ttgaaaaatc tcatgttcag ttatcaataa aatcttttca
     8041 tctacaaaat gaaaaccatg tctgagatta ccctctatta agtttacaga ttctttacag
     8101 atatttgtct tatctctaga atccaattta atctgatatt cctctaacat atcctccaat
     8161 gttttacttc ccattgaatt gctagactgc agaataatgg tgtaatccat ttttttatat
     8221 cgttcaattt cttcttttag aaaagaaaac tgattgaaaa attcctgcat aggatattga
     8281 ttgaattgat aaattttgtc aaatttgaga tttcctaaac ccttttgaag attagagaaa
     8341 aaggtcactg gactttgttt tttatagatt tgttcaatat cagaaaaata ctgcatatca
     8401 gaaaatgctt tactattctg taattcttct gtaaagtact gcgctaagtc tctttcaaag
     8461 acttcatact gattcatcaa tttttgataa tcatcaaaga atattggggt atctttttca
     8521 atataatcaa agacagtcca tgtcttatca tagcacaaag ataaaaactt ccgagagtct
     8581 gcatgacttt gtttttggtg aaaacttgaa agaatttctt ctaggtatga tttcaaaata
     8641 ggtgataaag tttttgaaat ttgtttttct aaagctgact gtcctcgttg ataatccttt
     8701 tctctcaaaa gcatatcact agctggaaag atagtgagtt ctgtcttatt ttctttcgat
     8761 aattgtgttt ctacttcaaa tgacctgata ccatcaattt catcaccaaa aaactcaatt
     8821 cgacaaggtt ctaactggga tatttcaaaa atatctaaaa tatctcctcg aagactaaat
     8881 tcgccctgag tttgtacttg agtaactttt cgatagccat tttcctttaa ctgatggata
     8941 aacgcgtgtt gatcatattc ttcaccaact gagattttta caatactatc tttgaatgca
     9001 ttgggagacg gtaaaatcaa tcgacttgct acgatattac aaactaaaat ccctttctta
     9061 gatgaatcag tcaaaaaacg caaggcttca acccgtgaaa taattttttc ctgtgaagac
     9121 atcaaaaact ccaccatagg agcatcatct accaaaaatg gatagacgag ttcctcaccc
     9181 aagatagata taagatcact aacaagtcct tctgcttctc cataagttga cgtcaataac
     9241 acaatcctat cttctttttc taaactgctt gcaattgcaa gagccttagt agatgttgat
     9301 aaaccaagta ttagttgtct tttcttatct gttaaatttt gatgccattt tttaatctga
     9361 tcattttctg agaataaatc taataaggtc accatttatc cgttatacct ctgcattgtt
     9421 ttctcaaaat ttttctcttg taaatagtag tttacagaat cgtcaacttt gtcaatagac
     9481 tgtaaaatac cgatataatc atccctgtca aacttactca aaacatgatg aacaactgac
     9541 ataccatttt taggtcttcc aattccaatc ttaacacggt taaagacctg agttcctata
     9601 tgttgaataa tagacttgat accattatga ccacctgctg agccttttgc tcttaaacga
     9661 attttcccaa cttccatgtc aagatcatcg taaatgataa gtaaatcgtc aatatccaaa
     9721 ccatagtaag ttaataaagc atgaactgct tttccacttt cattcataaa ggtcgttggt
     9781 ttaaccagat aaattttttc tccatttagg aaaaaggatg ctaggtcagc ttgaaatatc
     9841 ttatcgtgtg taaaagtgac attctgtttc ttcgctagtt gatcaatcaa cataaaacca
     9901 acattgtgtt ttgtttcaaa atatttatcc cctggatttc ccaagcctac aagtaatttg
     9961 gtcatttatt tttcctttca aaagccaaaa gggttggaat tttttttcca acctaattga
    10021 caccatttat taatttttag acattaaagc ggaattccat gatatcgcca tcttgaacga
    10081 tatattcttt tccttcttca cgcaagcgtc cagcttcttt tacggccttt tcagatccgt
    10141 atttcactag atcttcatat gacatggtta ctgcacgaat aaagcctttt tcaaagtctg
    10201 agtggataat accagctgct tgaggagcct tcataccacg tttgaaagtc caagcgcgaa
    10261 cttctttttc accagctgtg aagtaagttc ccaatccaag caagtggtaa gctgcacgcg
    10321 tcaacttatc tacacctgat tctgtcaaac caatggcttc aagaaactct tttttatctt
    10381 catcatccaa ttcagaaatt tcttcctcag cacgcgcaga aataacgact acttcagcat
    10441 tttctgtcgc tgcaaattca cgaatttgtt tgacatagtc gatagagtca ggttctgaaa
    10501 ccacatcctc gtccacatta gctacataaa gaactggttt agtcgtcaaa aggaaaagac
    10561 ctttgacaac cttttgttcc tcatctgtaa attcaatggt acgagctgat ttcccgtctt
    10621 ctaggactgg tttaatcttt tgaagaacat tgaattctgc tactgattct ttatcttttt
    10681 gcgtacgtgc catcttttct acacgcgcat atcgtttgtt cactgattct aagtcagcaa
    10741 gaatcaattc cagattaatt gtatcaatat ctgcaagtgg atctacaaag gcgtcttcac
    10801 gtccttgctc gcgcatcaca ttttcatcat caaaagcacg aactacgtga acaatcgcat
    10861 ctacttcacg aatattggcc aagaatttat tccctagccc ttctcctttt gaagctcctt
    10921 ttacaatccc tgcaatatct gtaaattcaa atgttgtggg aactgtcttt ttaggagtta
    10981 tcatttcagt tagtttttgt aggcgttcat ctggaacttc caccattcca acatttggat
    11041 caatagtcgc aaatgggtag tttgctgcct ctgctcctgc ttttgtaatt gcattaaata
    11101 atgttgattt accaacgttt ggcaaaccaa cgatacctgc tgtcaaagcc atatttctca
    11161 ttctccgttt tcatttcaat ccctaatatt ataacacaaa aagggataaa gtgctaaccc
    11221 tctaactaag ggttctcagt caataatttt attcattttt cgctcaaaat catatcgccc
    11281 catcatgaca acatgctcac aattactgca ttttattttg atatctgctc ctacacgtgt
    11341 aatttcccaa cgattagcct ttttaccagt cgacttgatt gtacaagcgt gtgatttttt
    11401 catctcaaca aaatttccaa cttgatacat actactctcc ttttcttttt cgattatatc
    11461 ataaaagagg cgagccaggc tcaacctctt tcacttaatt tgtacgaact ggtgtaatga
    11521 gctgcatgaa gtcttcgtca gtatctgctg gcacaagagt aaatggacga acagctgaga
    11581 taaagctaat ggtcaccttt tcgctattta aagctttaag agaatcaatc aagtaagttg
    11641 ggttgaaact aatggtcaaa tcttcaccag taacctgatc agtatcgatt tcttcgttta
    11701 ctttaccaac ttctggagag tgaacatggg cgctaacaac cccatcctta atttcaagtt
    11761 tcacagtacc attttgagtc gcacttgata aaagacgggc acgctccatt gactggcgta
    11821 agtttaccac attaaaagta atagtagtgt taaagtctgt tggaatcaag cgatctgtat
    11881 caggatagtt tccttctagg agacgagtat agaagctaat attttcgctt ctaaagagga
    11941 tttggttatt ggcaaagaaa atctctacag tttcgatatc atctgtaaat accgctgaaa
    12001 attcgcgtag agaacggcta ggaattacga catcaaaatc atcactattt ttttcaagag
    12061 tcaatttttt ctggcttagg cgatgagagt ctgttgcaac tgtttttaac tctttgtgtt
    12121 gactcaatac gaagtggaca cctgttaaaa tcggacgact ctcttgtgta cttgcagcaa
    12181 aggctgtttc attaataatt ttcttgagta attttgtttc aagtattaaa ggagtgcttg
    12241 ctgaaatttc ttggattcgt ggatattgtt cgctatcttt tccttttagg gtaatttctg
    12301 atttgccact ggttaaaaca atttgatttt gttcaatttc tttaaaatca agagtcacat
    12361 caggtaaact agatactaca ttgataaaga aagaagcttc aagaaggatc gaacctaaag
    12421 aagtaattaa caaaccagca tcttcatttt tttgagaaat aaaattttca attgaaattt
    12481 gaccatttga accaattaaa gtaatacctt cattggtcac gtcaattttt actgttgata
    12541 aaataggaat ggcattttta gaactaatag ctctcttagt agtatttaat gcttgtagaa
    12601 ataaattttt attaattgaa aaatgaatca tggattctcc tttatttatt tttagtatta
    12661 gaaagataat agtaataata gagtctgtga aatctgtgga aaacagcctt taaacaagtc
    12721 atatcaagtt ttttagcttg tttaaaaaat gtggataaaa aagataaaaa actaaaagtt
    12781 atccacaaat tatttgattt tctttttgat tgattcaatt tctaaacgta aattatcgtc
    12841 ttgatcaatc aaagatttta ttttggcatg ggcatgaatg actgtggtat gatcttttcc
    12901 cccaaattcc ttcccaattt ttggaagact attatctgtt agttctctag ataaatacat
    12961 ggctacttga cgggccaaaa caatattttg aaggcgtcta cttcccttca tttctttgat
    13021 actaacacca taaaagttac caacttcagt ttggatttta tcaattggga tgacgagcat
    13081 ttggctaaca tcttgtttgc gggctctaat ggcttctgca gcaatatcaa tagtgatatc
    13141 cttgattttt tttactctgg caattaaagt gatgtcgttg atggctccct caagatctcg
    13201 aacatttgaa tcaaattgcc cagctaggta ttctagagta tcactttgga aattgtagcc
    13261 taaatgttcc gtcttacttt gtaaaatggc aatacgtgtt tcaaagtcag ggggtgtgat
    13321 agtttgtgtc aatccccaac taaaacgcgt gacaagcctc tcctcgagcc cttctagatg
    13381 ttttggacta cgatcactcg ttaggacaat ctgtttttgc ttgtcatgaa gggcgttaaa
    13441 ggtattgaaa aattcttcct gagttgcgac tttttttccg ctgagtgact gtatatcatc
    13501 gattaacaaa agatcaagac tacgataggt ctttttaaac ttttccattt ccccaagtct
    13561 taggtgatca agaaagtcat taataaagct ttcggcaggg atatatttaa cacgcgcatt
    13621 aggaatattt tttagaattt catttccaat agcgtttaat aagtgagtct taccaaggcc
    13681 tggtcctcca tagataaaaa gagggttata ggtcagagcc aaatcttcag agacagctaa
    13741 agcggctgat acagcccaaa catttccatc cccttgaata aagttatcaa aggtatactt
    13801 ttcttttaat cccgtatctg aataaggaat agatactaac tttggactat agtcataaag
    13861 agttaaattt gtagcttctt caacttgtga gctagtcgta tcttgaggtt tggtgaaaat
    13921 atagtgggga gttatttcag cgtcataaat ttcaaaacca gctactacaa taatatcttt
    13981 tagttgtttt tcccagacca tttccatttc agagcgaggt agaaatatag tggcaacatt
    14041 ttcctctacc ttgatgagtt cagcttgaat agcatagaaa tcatacatgg atcgagtcag
    14101 tctttcttgt gcaaattcta atatacgatt ccaaaattgt ttttctttca atcctttctc
    14161 ctcctttact atttaaaagt ttaatactag agatatttta ccatagatag caagaatttt
    14221 ccacaagctg tgaaaaataa tccacaatgt taccaaactt tatccacagg ttggggataa
    14281 aagaagaaat tattgattta ttaagctttt tatcgaaaaa catagtggat aaccttgtga
    14341 gataaaaaaa taaaagaaca gccttatttc aggctgttga taattctact atattcttct
    14401 tgatttgaaa aagaaataat gatttttcca ctgtcttttt tagatagttt aatttctaca
    14461 tctaatccga gtagttttct taactgtttt tcttcatttt gtatgaaatg attagttttt
    14521 tgctgtttct tttgtttttt ctctgtcaga agagtttcta acttccttac agaaatatct
    14581 tcttctataa tccgttgaaa gaaatagtct tgttgttcct tatttaaccc aactagggaa
    14641 cgcgcatggg cttgtgatag tttgccattt tctacttctg agagaatctg ttctggcaag
    14701 gaaagtaaac gaatggagtt gctgatatat ggacgagact tgcccatctt atctgcaatt
    14761 tcagcatggg tgaatccttt ctctacgaga gattcatagg cgcgtgcttc ttctattggg
    14821 tttaaatttt ctctctgtaa attttcaata atggactgga ccatcatctc ttggtctgaa
    14881 atctgtttaa caacagctgg gatagaccgt agaccagcta aaagtgaagc ccgatagcgt
    14941 ctctctcctg caaggatttc ataaccaata acaggagatt gacgaacaat aatcggttga
    15001 atgaccccat tttctttgat agactgtgct agttcatcta gcttttctct atcaaattct
    15061 tttcggggtt gatagggatt tttttgtata tctgtgatag aaatcatttc aaatttttcc
    15121 atgattctac actaacacat cttttctctt atgtaaagct ttctttacat agatgtcaat
    15181 taagattcta aatcacctga actcttgtta agtttgatag aggtagtttc ttctttcccg
    15241 ttacgatagt aggttatctt aatggtgtct ccgatagaat ggttgtaaag agcactttgt
    15301 aagtctgttg atgaagcaat ctctttgtca tctacttttg taattacatc gtatttttca
    15361 aggtgaccat tggcaggcat attactttgt accgaacgaa caactacacc agatgtaaca
    15421 ttacttggaa tattgagtct tctgatgtcg cttgtactca cattagataa attaaccatc
    15481 tggattccca aagctggacg cgtcactttt ccgttttttt ctaactgttc aataatattg
    15541 atagcatcat ttgcaggaat tgcgaaacca agaccttcta cagatgttcc tccatttgta
    15601 gcaattttac ttgaggtaat tccgataacc tgcccttgaa tattgatcag tgggccgcca
    15661 gagttacctg ggttaatagc agtatcagtt tggatggctt ttgtagaaat agcttgtcca
    15721 tcttccgatt ttaaggatac atttctattg agactggata cgataccttg agtgacagta
    15781 tttgcatatt cagaacctaa cgggctaccg atggcaatag cagtttctcc tacagttaac
    15841 ttactagaat caccaaactc agctactgtt gtcacttttt ctgaagagat ttttacgaca
    15901 gcaatatcag agaaagtgtc agctccgaca atttctccag gtactttagt cccatctgac
    15961 aatcgaatat ctactttgct ggcgccattt ataacgtgat tgttggtgac gatgtaagct
    16021 tctttatcat tctttttata aataactcca gatccttcac tagagattcg ctgagaatct
    16081 gtgtcagtat catcattgcc aaatacgcta ttttgtctgt ttgccgaata agtaataaca
    16141 gaaacaacag catcttttac tttgttaaca gcctgtgttg ttgaattttc gttcttatag
    16201 gcagtttgtg taatagtact attattgtta gagttgttta cactactttt ttgagttagt
    16261 tgagttattg aaaaactacc caaggctcca ctaaaaaagc taatgacgat aacgactaat
    16321 aattgaaacc attttttgta aaatgttttt agatgtttca tatttgcctc catatgtttg
    16381 aattactgaa agtataaact gactagctta attataactt aaacacaaaa gttttacaca
    16441 aactgtggat aactcttttg aaactgtgat tttcttaatt gaaatctatt ttttattttg
    16501 tgaataagat gtgaaaaaat agagaatatg ttagaataga gtcatgaaaa ttaaagttgt
    16561 aacagttggg aaactgaaag aaaagtattt aaaagatggt atcgcagagt attcaaaacg
    16621 aatttctaga tttgctaagt ttgaaatgat tgagttatca gatgaaaaaa caccagataa
    16681 ggccagtgaa tcagaaaatc aaaagatttt agaaatagaa ggtcagagaa ttttatcaaa
    16741 aattgctgac cgtgatttcg ttattgtgtt agccattgaa gggaaaactt tcttctcaga
    16801 agaatttagt aagcagttag aagaaacttc tataaaagga ttttctactc ttacttttat
    16861 tattggggga agtttaggat tgtcatcatc tgtaaaaaat agagccaatc tttctgtcag
    16921 ttttggtcgc ctaaccttgc ctcatcagtt aatgagacta gttcttgttg aacaaatcta
    16981 tcgcgctttt acgattcagc agggattccc ctaccataaa tagaaaattg acttttaatt
    17041 gaatttttgg tagaataatt gtgttaggtc tcatagctca gctggataga gcattcgcct
    17101 tctaagcgaa cggtcgcagg ttcgaatcct gctgggatca atataatagc aaagctggga
    17161 attttcccgg cttttttctt aaaaaagtac actttgggag aaaaaaatga cagttgagag
    17221 aattttatct aaagtgaaat tccattttgt ataatggttt ttgtaagtta gcttacaaga
    17281 aaaaacattt taggagattt tattatgaaa aacacagtta aattggaaca gtttgtagct
    17341 ttgaaggaaa aagacttaca aaatattaaa ggtggggaga tgaggatttc aagaatcatc
    17401 cttgattttc ttttcctacg aaaaaagtaa tgaaataagg agaaagagta atggatttac
    17461 ttggatttgg gacagttatt gttcattttt taattattag tcacagttac cgtttaattt
    17521 gtaaaggtcg aataaataga aaagaattat acatttttgg tgcttataca ttactaactg
    17581 aaatagtact tgaattttcc ttttatcttc tatatttaga taaaataggg attgaaagat
    17641 ttttatttcc tttgggctta tattcctatt ttcgatggat gaaacagtat gagagggata
    17701 gaggactatt cctaagttta ctactatctc ttttatatga gagcactcat aactttctgt
    17761 ccgtaacttt ctcctctata acaggagata attttgtttt acaatatcat ttcccattct
    17821 ttttcgttgt gacggtgtta acctattttg ttacattaaa aatcatttat tatttccatt
    17881 tggaactagc ctattttgac aaggactacc tttatccttt cttgaaaaaa gtattttttg
    17941 ctttactatt gctacatatt gtatctttcg tttcagatat ggtaagtacg attaaacatt
    18001 tgaatagttt tggaagtatt ttgtcatcta ttgtctttat ctctctcctt ttgaccttct
    18061 ttgcaatgaa ttctcataaa gttcaaatgg agaaagagat tgctttgaag cagaagaaat
    18121 ttgaacagaa acatttacag aattacacag atgaaattgt tggtctgtat aatgaaatcc
    18181 gtggttttcg acatgattat gctggaatgc ttgtcagcat gcagatggca attgacagtg
    18241 gtaatttaca ggaaattgac agaatttaca atgaagtttt agtcaaagca aatcataaat
    18301 tgcgttcaga taagtacact tactttgatt tgaacaacat agaagactca gctttacgaa
    18361 gtttggttgc tcagtcaatt gtctatgctc gaaataatgg tgtagagttt acactggaag
    18421 taaaagatac gattaccaag cttccaattg aactattgga tttggttcgt atcatgagcg
    18481 ttttattgaa taatgctgtc gaaggatcgg ctgatagcta taaaaagcag atggaagtag
    18541 cagttattaa gatggaaact gaaacagtta tggtgattca gaattcatgt aaaatgacga
    18601 tgactccttc aggagatcta tttgccttag gattctccac taagggaaga aatcgcggag
    18661 tcggattaaa taatgtgaaa gaactactag ataagtacaa caatattatt ttagaaacag
    18721 agatggaagg cagtacattt agacaaatca ttagatttaa gagggaattt gaatgaaagt
    18781 tttaatttta gaagatgtta ttgaacatca agtgagacta gagagaatat tggatgaaat
    18841 ttcgaaagaa tcgaatattc caatatcata caagacaacg ggaaaagtcc gtgaatttga
    18901 agaatacatt gaaaatgatg aagtaaatca gctttatttc ctagatatcg atattcatgg
    18961 aattgagaaa aagggatttg aagtggctca gctcattcgt cattacaatc cttacgctat
    19021 tattgtcttt atcactagtc gatcagagtt tgcgactcta acctataaat accaggtatc
    19081 agccctagat tttgttgata aggatatcaa tgatgagatg tttaagaaga gaattgagca
    19141 aaatatcttc tacacgaaga gtatgttact tgaaaatgaa gatgttgtag attatttcga
    19201 ctacaattac aagggaaatg atttaaaaat tccttaccat gatattttgt atattgaaac
    19261 aacaggggta tctcataaat tgcgcattat tggtaagaat tttgcaaaag agttttatgg
    19321 taccatgaca gatattcagg aaaaggacaa acatactcag cgattttatt ctcctcacaa
    19381 gtcatttttg gtaaatatag gcaatatcag agaaattgat cgaaaaaact tagaaattgt
    19441 tttctatgaa gaccatcgtt gtcctatttc aagattaaaa attagaaaat taaaagatat
    19501 tttagagaaa aaatctcaaa agtgattgac aattagcaag aaattgatat aatggttata
    19561 tctgctacag atagaaggtc cgttggtcaa ggggttaaga caccgccttt tcacggcggt
    19621 aacacgggtt cgaatcccgt acggactatt ttatccgcca tagctcagtt ggtagtagcg
    19681 catgactgtt aatcatgatg tcgtaggttc gagtcctact ggcggagtat agataaaagg
    19741 gaacacagct gtgttcctct ttttgtatca atttgtatca ccaagcattt tcataaggaa
    19801 gtctgttatt tcttgagaac tttctttttt tccatgtgca atccaagttt ggcagacacc
    19861 aaaaagtgca tgagttagat agatgctact atattctaat tcagtggtat ttagattcag
    19921 ttgcataaat cgcttttgta aatctgtact aagcatgata tgaagtttat ttcgtaagaa
    19981 attttggatt tctttagtcc cattttcaga aagaagggca gccagaagtg gttctgactc
    20041 tagatattca aaaacttcta aaatagcgtc tcttttgtga tgagcatgtt tttgaaaaat
    20101 atattcaaat gtatggaata gcttgctttg atagtgctca atcatatcat acttatcctt
    20161 atagtgagta tagaagctgg aacgactaat tccggctttt tctactaatt tgacagtaga
    20221 aattttatca aatggctgtt ccatcagtaa ttgtaccata gcattttcaa tagttcgctt
    20281 tgtttttaag cgtttgttac tttcttgcat atttcctcct tgtaaacaaa ttagactata
    20341 tgtctaaaaa tagatttttt atcttgtaat ttagattttt taatgtataa tctattatat
    20401 caaaatttta gacaatatgt ttaaaaaagg agaaactatg tttaaagaat ggaaagcaat
    20461 ttaaaaaaaa ccaaccttta ttattgtcat gatcgggatt tctcttattc cagctctgta
    20521 caatatcata tttttgtcat caatgtggga tccatatggg caattgtctg acttacctgt
    20581 ggcagttgta aataatgata aagaggcttc ctataatggt aatactatgg caataggaaa
    20641 agacatggtg tccaatttaa aagaaaataa aaccttggat tttcattttg tagatgaaga
    20701 ggaaggaaag aagggattgg aagatggcga ttactatatg gtagtgactt taccaagtga
    20761 tttatctgaa aaaacaacta cattatccaa tcttcaatcg acagcagctt atcaatcatt
    20821 gacaagtgag caacaaactg agataagtga ttctgtatct caaaattcaa ctgatagtat
    20881 tcaatcggct cagtcaattg tagctttagt acaaggttta cagggaagtt tagaaaactt
    20941 acaaaatcaa tcttctaatc tttcgacttt aaaaaatcaa gctaatcaag tattacctat
    21001 tacttctact tctttgatag gattgtcaag tggattaaca gagatacaag gagatgttac
    21061 tagcaaatta gttcctgcca gtcagtcgat tgcatcaggt gtaaacgcat atactacagg
    21121 tgttgataaa gtttctcagg gcgcaagtca actaagtgaa aaaaatgcca ccttgacagg
    21181 tagtttggat aaactagttt caggctcaaa caccttgaca caaaaatctt ctagattgac
    21241 agcaggagtt ggttaattac aatcaggatc tgggcaatta gcagacaaat ccagtcagtt
    21301 actttcaggt gcttctccat tagagaatag agctaataaa ttggcagatg gatctaggaa
    21361 actagcagaa ggtggaacaa agttaacttc tggattggaa gatttacaga caggacttgc
    21421 ttctttagga caaggactag gtaatgctag tgatcaactc aaatcagtat caacagaatc
    21481 taaaaatgca gagattttgt caaatccact caatctttca aaaacagaca atgatcaagt
    21541 tcctgtaaat ggaatcgcaa tagctcctta tatgatatca gttgctcttt ttttgcagca
    21601 atatcaacaa atatgatatt tgcgaaattg ccttcaggac gtcatccaga gagccgttgg
    21661 gcttggttga aatcttgagc tgaaataaat ggtattatag ctgttttggc aggaattttg
    21721 gtatatggag gagttcagct tattggttta actgctaatc atgagatgag aatatttatt
    21781 ctcatcatcc taacaagttt agtattcatg tctatggtga ccactttagc aacgtggaat
    21841 agccgtatag gagctttttt ctcacttatt ttgcttttac tacagttagc atcaagtgca
    21901 ggtacttatc cacttgcttt gacaaatgat ttctttagat ctattaatcc ctggttacca
    21961 atgagctatt cagtttcggg attacgacaa acaatctcta tcaacaagtc attttcctag
    22021 ctgtcatact agctctattt actggtttag gtatgctagc ctatcaacat aagaaaatgg
    22081 aagaagatta aaaaaatcga ccgattaact ggtcgatttt ttatgcctta gatgactttc
    22141 gtctgtgatt atagattcca aatagtaaga gagaagtaaa ggaacagatt gctccagtaa
    22201 taaaaccatt gggaatgaag gaaagtgtaa tagttccttt ccccttggga atgtcaactt
    22261 tcataaatcc agtttgagct tgtttaattt ctattttctt accatcttgg taggcagacc
    22321 aacctttgtc ataaggaatg gtgaagaaaa tagatgtatc ttgttggaca tcatatgtag
    22381 caaaaacctt gtttttagaa gttgatactg tgacaggttg ttctttaatt ttttgaattg
    22441 cctcggtgaa agttttggta tctaaacgat agaaggtagg agattcaaat gatacttgtg
    22501 aatttccagg gaaactaaca ttgatattga aagttttttt ctctttagta tatcctagat
    22561 taaagaagga gaagacatta tcagttgtaa aagtcttttt ttcaccattt acaaggatgt
    22621 caaccttctt ttgtttatcg ttagaaaagt gaaggtttat gaaagagaga taaacttggc
    22681 tgttttctgg aacttcaatt tgatactgga ttgctgcatc ttcatttgaa gaacttgtga
    22741 cactaatcaa atcattagta ttttctattt tttctgtttt ttcataaggt attggagaaa
    22801 aataatcaaa attgacgtta gcaagttgat ttaaaaatga ggcctgatta tccaaggtat
    22861 gttcattgaa cttgacatca ttgtaaacag attgactagc aactgcaatc ggaagagagt
    22921 attgattttc atatagggta agattatctt tttgatagat atctttaaag ccatacttat
    22981 caataggact gtctgagata ttgtactgga taccaaataa actatcagcc aaaatactat
    23041 tatttgcata tcggagattg agattagtcc cagaggattt aaaaccaagt ttatctaaag
    23101 tagagcttga tgaacgattt cgaacagatg aaaattgaga gattccattg tagttgaatt
    23161 tcatactgtc atttcctgtc tgagtttgta gtttttcagt acgagtaaat tgatttccaa
    23221 tatatgttga gaaagattcc atagctagga tatctcgact ataagcactt cgagaagcaa
    23281 atccccattc cttagcaatt ccgtccattt gagatgaagc atttaaactc atttcaacca
    23341 gtataaataa agagattaga atggcaaata gattcacaaa tataaacttt ttgataactg
    23401 caaggagtaa aagagaatag acaaccaaaa attcaagagt aagcagaata ttcaaatctg
    23461 ttaaaaaaga ataatgcgat tttagataga tggtagctaa aaatcctgct actacaagaa
    23521 aaagcgaaac taaaaaattc cagactttaa gttctttcag acgctttaag acttctgctg
    23581 ctgtgtaaat taacaaggta gagaaaatcc aagcatagcg atgtaaaaac atgtttggag
    23641 tatgcatgcc ttgccaaaat aagtcaagag cttctatgta aaagcttgca attagaaatg
    23701 caaagaatat tacatatatg agtttcacgt gaaacttaat agatttcagc gtaaaaaata
    23761 aaatggtcaa aataaaggga aatagtccaa caaaaatcat tgggatggcc ccatactttg
    23821 ttgtgtcaaa ggaaccaatg aattgcttag caaagagatc aagataccag ctactttcag
    23881 tttgaaactt tgtaacttca gtcaattttt ccccatgtgt ctgtaaatca aatagagtgg
    23941 gaatagtcat aatcaaacta gccataccag ctaaaaagga gataactatg aaatcaagaa
    24001 cagatgattt tcgagtctta aagtcccacg aaatttgaca gagataccag aaaataagaa
    24061 acaatactgt catatatcca aaataataat tttgaataaa taagattgac agacttgtaa
    24121 agtacaatag gagtttcttt tcagttatca gtagatgtaa accagttata attaaaggaa
    24181 tcaagataaa aacatctagc caggttttta tctctaattg actgacagtg aaactcatca
    24241 gagcatagga agtagataag gctagtttta aagtctgagg gatagattga aacaatttat
    24301 tcaaactaaa aaaggttgac agaccaatca atccaaattt taagagagtg gtcagataga
    24361 cagcatctgg catattcgtt agatcaaaaa agtaaactag aggcgcgaga aaactaccca
    24421 agtaataact agatagggca tagaagttta gccctagacc acttgtaaag gtgtaaaaca
    24481 gactactatt tccatgtagg atatttcgta aggctacatc aaaaataacg tattgatgaa
    24541 agccatctcc taatagagga gagttgtcgc tattccagta gataccttga gatagatata
    24601 ctccagacat aatcactaca ggaatgatga aagaaataaa ataggttcga tatgttttta
    24661 aaaatgattt catgttacct cgtagaatga tagaaaactc agttggttaa cccaactgag
    24721 ttttgaagtt ttatttagtc tttccaaagt tctttaactt ttgcttgtac ttctgcattt
    24781 tctaggaatt catcgtaggt ttcatcgata cggtcaatga cgccattttt agataagaca
    24841 atgatatggt tagccaaagt ttgaataaac tcgtggtcat ggctggcaaa gatgattgat
    24901 tctttaaagt ttttcaatcc atcattcaag cttgagatag attccaagtc caagtgattt
    24961 gttggatcat caagtacaag gacatttgat tttaagagca tgagttttga aagcatgaca
    25021 cgaacttttt ctccccctga caagacattt acaggtttgt taacttcatc tccagagaag
    25081 agcatacggc cgaggaaacc acgtaggaaa gtattgtcat catcttcttt acttgcgaat
    25141 tgacgcaacc agtcaagaat tgattctcct cctgcaaaat cagctgagtt atcttttggt
    25201 aggtaagatt gactagttgt aactccccac ttgacagttc cttcatagtc aatatctccc
    25261 atgattgcac gaattaatgc agtcgtttga atatcatttt gtccaataag tgctgtctta
    25321 tcatctggac gcaagatgaa actaatatta tccaagatag tttcaccatc aatctttaca
    25381 gttagatttt ctactgtcaa gagatcatta ccaatctcac gttccgcttt aaagttgata
    25441 aatggatatt tacgactaga tggtacaatc tcttctagct caatcttatc aagcattttc
    25501 ttacgtgatg ttgcctgcct tgacttagaa gcattggcag agaaacgagc aacgaattct
    25561 tgcaattgtt taattttttc ttctgcttta gcattacggt ctgctagcaa tttagcagca
    25621 agctcagaag attccttcca gaagtcgtag tttccgacat agagtttgat ttttccaaag
    25681 tcaaggtcgg ccatgtgagt acaaactttg tttaagaagt gacggtcgtg ggatactacg
    25741 ataactgtgt tatcaaagtc aattaagaag tcttctaacc aagtaatcga ttggatatcc
    25801 aaaccgttag taggctcgtc caagagaaga acatctggtt taccaaaaag tgctttggcg
    25861 aggagaacct ttactttttc accgttggcc aattcgctca tgttttggta gtgtaattct
    25921 tctggaatgt ttaggttttg aagtagttga gaggcttcac tctctgcttc ccaacctcca
    25981 agttcggcaa actctccttc gagttcggca gcacgaaccc cgtcctcgtc tgagaaatct
    26041 tccttcatgt agatagcatc tttctctttc atgatgctat aaagtttttc atttcccatg
    26101 ataacgacat caatggcacg ttcatcttcg tagtcaaagt gattttgacg aagaacagag
    26161 agacgttcat ctggaccaag agagatgtga ccagtagtag gttcgatatc tccagctaaa
    26221 atttttaaaa aggttgattt tccggcacca ttagcaccga ttaatccgta agtatttcct
    26281 tctgtaaatt tgatattgac atcatcaaaa agtttgcgat cactaaaacg tagtgaaaca
    26341 tcagatactg taagcaatat ttttctccta tatgtgtaat atatttattc tactagaaaa
    26401 tacagaaata ttcaaatttt tatttttcaa ttttgtgtaa attatattta cagtatcctt
    26461 tacacaaatc tgtaaaaagc aaggctgatt tattttgata aattacggtt atttcattaa
    26521 aaaaatgcta taattgaaag gactatatcg aaggagaaca aaatgactaa acccattatt
    26581 ttaacaggag accgtccaac aggaaaattg catattggac attatgttgg aagtctcaaa
    26641 aatcgagtat tattacagga agaggataag tatgatatgt ttgtgttctt ggctgaccaa
    26701 caagccttga cagatcatgc caaagatcct caaaccattg tagagtctat cggaaatgtg
    26761 gctttggatt atcttgcagt tggattggat ccaaataagt caactatttt tattcaaagc
    26821 cagattccag agttggctga gttgtctatg tattatatga atctagtttc gttagcacgt
    26881 ttggagcgaa atccaacagt caagacagag atttctcaga aaggatttgg agaaagcatt
    26941 ccgacaggat tcttggtcta tccaatcgct caagcagctg atatcacagc tttcaaggct
    27001 aattatgttc ctgttgggac agatcagaaa ccaatgattg agcaaactcg tgaaattgtt
    27061 cgttctttta acaatgcata taactgtgat gtcttggtag agccggaagg tatttatcca
    27121 gaaaatgaga gagcagggcg tttgcctggt ttagatggaa atgctaaaat gtctaaatca
    27181 ctaaataatg gtatttattt agctgatgat gcggatactt tgcgtaaaaa agtaatgagt
    27241 atgtatacag atccagatca tatccgcgtt gaggatccag gtaagattga gggaaatatg
    27301 gttttccatt atctagatgt ttttggtcgt ccagaagatg ctcaagaaat tgctgatatg
    27361 aaagaacgtt atcaacgagg tggtcttggt gatgtgaaga ccaagcgtta tctacttgaa
    27421 atattagaac gtgaactggg tcctattcgt gagcgccgta ttgaatttgc taaggatatg
    27481 ggagaagttt ataatatgat tcaaaaaggt agtgaaagag cgcgtgaagt tgcgggtcaa
    27541 accctatctg aggtaaaagg ggcaatggga cttcattact ttaactaagt ttattttaca
    27601 agaaactatc ttttctatct cgaagaaaag atagtttttt atttacccct gtaacatttg
    27661 acaaattttt atagaatggt atgatagata caatataaaa agagtcaagc tcaaaaagaa
    27721 agaaaagagg aaacttcgaa tgtctaattg ggacactaaa tttttgaaaa aaggttttac
    27781 ctttgatgat gtattgctta ttccagctga aagtcatgtg ttgcctaacg atgcagattt
    27841 aacaactaaa ttggcagata atttgacttt aaatatccca attattaccg ctgccatgga
    27901 cacagttaca gagagtcaaa tggccattgc tattgctcgt gcaggcggtc tcggagttat
    27961 ccataaaaac atgtcaattg ctcaacaagc agacgaggtt cgtaaggtaa aacgttctga
    28021 aaatggagtt attattgatc cgttcttctt gacgcctgaa catacaattg ctgaagcaga
    28081 tgagcttatg ggtcgttacc gcatcagtgg tgttccagtt gttgaaacac ttgaaaatcg
    28141 taaattggtt ggtattttga caaaccgaga tcttcgtttt atttcagatt ataatcaacc
    28201 aatttcaaac catatgacta gtgaaaatct tgttactgct cctgtgggta cggatcttgc
    28261 aacggctgag agtattcttc aagagcatcg tattgaaaaa cttccgttgg tcgatgaaga
    28321 aggcagtctt tctggtttga tcactatcaa agatattgaa aaagttattg agtttccaaa
    28381 tgcggctaaa gatgagtttg gtcgtcttct agttgcaggt gcagtaggtg ttacttcaga
    28441 tacatttgaa cgtgcagagg ctctttttga ggcaggagcg gatgcgattg ttattgatac
    28501 tgcacatggt cattctgcag gtgtcttgcg taaaattgcc gagattcgtg ctcatttccc
    28561 agatcggact ttgattgctg gaaatattgc tactgctgaa ggtgcacgtg ccctttatga
    28621 agcgggtgta gacgttgtta aggttggtat tggaccaggt tctatctgta ctactcgtgt
    28681 gattgctggt gttggtgttc cgcaagtaac agctatctac gatgctgcag ctgttgcgcg
    28741 cgaatatggt aaaacgatta ttgctgacgg tgggatcaag tattctggag atattgtaaa
    28801 agcacttgct gcaggtggaa atgctgttat gcttggatct atgtttgctg gaactgatga
    28861 agctccaggc gaaactgaaa tcttccaagg acgtaaattc aagacttacc gtggtatggg
    28921 atcaattgct gctatgaaga aaggttcaag cgaccgttat ttccaaggtt ctgtcaatga
    28981 agcaaacaag cttgttccag aaggaattga aggtcgtgtt gcttataaag gagcggcagc
    29041 tgatattgtt ttccaaatga ttggtggtat tcgctctggt atgggttact gtggtgcagc
    29101 taaccttaaa gaactacacg ataatgctca atttattgaa atgtctggtg ctggtttgaa
    29161 agaaagccat cctcatgatg tgcaaattac taatgaggca ccaaattatt ctatgtaaaa
    29221 aacattgtaa aagaactcca gtgaaaacag gagttctttt acaatgttgt caatttccat
    29281 ttacagaagc tttaccatcc tgaatagtga agatacttag attttctggc agattttgaa
    29341 gatggtctaa gcttgttgtt gtgataaagg tttggattga ttgagaaatc gtttctaata
    29401 attttaactg tctagtgttg tcaagttcac tcatcacatc gtcaagcagt aatatcggag
    29461 attctgtggt aatgctttcc attaattcga tttctgctaa ttttatcgag aggacgagac
    29521 tacgatgttg accttggctt ccgaaactag catccatccc atttatataa aaagaaatgt
    29581 catctcgatg aggaccgaca ccagtattct ttttaaataa atctctggat ctactttttt
    29641 ctaaagcaat tttgaaagat tcggataagt tttgtttgtc agttatattg acagaagatt
    29701 gataggatat tgacaactct tcgatctgat tagagagttc aaaatgtttc ttacgcccaa
    29761 atgattctag tttttttatg aaatctaagc ggtgattcat tacacgacat ccataatcaa
    29821 ctagctgatc atctaacaca gaaaggaatg tttcatctat tttttgatct gattttaggt
    29881 aagtgtttct ttgctttagg atgtggttat aattggttaa gtcagataag tagattggct
    29941 taatttgccc aagttccata tcaatgaatt ttcgtcgaat cgaaggtgct cctttaatta
    30001 gttgtaaatc ttcaggagca aataagacaa cattcatgtg tcctacataa tctgaaaggc
    30061 gtgcctgttt taagtgatta acttttgtta cacggccttt ttgtgttagt tcgatttcta
    30121 ggggaatgga tccagttttt ttctgaacga gacctgaaag atgaagttgt tcctcatcaa
    30181 aatgaatgag atttttatct gttcgagttc gatgactacg cgttaaggct aaaaaataga
    30241 tagcctctaa catgtttgtt tttccttgtg cattacgtcc caaaaagaca ttcaatttag
    30301 gattaaagtc tattttcgtt tctttgtaat tacgaaaagt cttgagagat agatgttgta
    30361 gccacatgat tatctaccag ggaatcgtgg agcttgttgg cttttaggtg atgaagcagg
    30421 tttcgatttg tcttttttaa ctcccttatt catctttttg acaagtttag cgatccgttc
    30481 tttttcaact ttatcagctt ggtattcatc ttgttcttca gaagtaggtt gtgtcaacaa
    30541 gatgtcaatg ttcatgtcag ggatgtcaac tttatcgcca atacgaagtt tttttccacg
    30601 acgactctct aattccctat taaagtaaac agaatgttca gagagaaatg atttaatagc
    30661 tcctccgcta tgtgtaattc caagttcttt gagtagtgct tggagggtaa taaattcttc
    30721 aaataatttg tattccataa ttcacctcaa tctttggtat tataccatat tttcctaaaa
    30781 atagtgagag agacagcgag aaatgtaagc gatttttatt tcaaaagtgt tacagggaac
    30841 aagaaaattt caggttttcg tgatataata gaagtctgta tataaggagg taaatcatgg
    30901 agttagtgca tggaatttca acacatttta tccaatcaaa aaagtttaaa acaaacaaaa
    30961 ttaccgtgcg ttttaccgct ccattatccc ttgatacgat tgcaggtcac atgttgagtg
    31021 caagtatgct agagactgct aatcagatgt accccacttc tcaagatttg aggagacact
    31081 tggccagtct atacggtaca gatatgtcaa ccaattgttt cagaagaggg caaagccaca
    31141 ttatagaatt gacatttacc tatgttcgtg atgagttttt aagtaggaaa aacgtgctaa
    31201 cctctcagat tttggaactt gtaaaagaaa ctcttttttc acccgtagta gttgataatg
    31261 ggtttgatcc ggccttattt gaaattgaga aaaaacaatt gctagcaagt ttagcagctg
    31321 atatggatga ttctttttat tttgcacata aagaattgga taaattgttt tttcatgatg
    31381 aacgtcttca attggaatat agtgatttac gaaatcgtat tttagctgaa actccacaaa
    31441 gttcttattc ttgtttccaa gaatttttag ccaatgatcg aatagatttc tttttcctag
    31501 gtgattttaa tgaggttgaa attcaaaatg tattagaatc atttggcttt aaaggtcgaa
    31561 aaggagatgt gaaggttcag tattgtcaac cttattctaa tatccttcag gaaggtatgg
    31621 ttcggaaaaa tgtgggacaa tccattttgg aattaggtta tcattactgt tctaaatatg
    31681 gtgatgagca acatttaccc atgattgtaa tgaatggttt acttggtgga tttgctcact
    31741 ctaagctctt tacaaatgtc cgtgaaaatg ctggattagc ttataccatt tcaagtgagc
    31801 ttgatttatt tagtggattc ttgaggatgt atgctggtat caatcgagaa aatcgtaacc
    31861 aggctcgtaa aatgatgaat aatcaactgc ttgatttaaa aaaaggttat tttacagagt
    31921 ttgagttaaa tcagaccaag gaaatgattc gttggtcgtt gttactttct caagataatc
    31981 aatcttcatt gattgaacgt gcttatcaaa atgccttatt tggaaaatct tcagcagact
    32041 ttaaaagttg gattgcaaag cttgaacaaa ttgacaaaga tgctatttgt agagtagcta
    32101 ataatgtgaa actacaagcg atttacttta tggaaggaat agaatgacaa aggttgtttt
    32161 tgaagaaaaa tactatccag ctgtaaaaga aaaggtttat cgaactcgtt tggccaacgg
    32221 attgacagtt gctcttttgc ctaaaaagga atttaaagag gtttacggga gtgtcactgt
    32281 acagtttggt tcggtagata cgtttgtcac agaagttgac ggagatgtaa aacaatatcc
    32341 tggaggaatt gctcattttc ttgaacataa attatttgag agagaagatt ctagtgattt
    32401 gatgtcggct tttacgagtc taggtgcaga tagtaatgcc tttacaagct ttacaaaaac
    32461 aaactatctt ttttcagcaa cggattattt tttagaaaat ttagatttac ttgatgaatt
    32521 ggtaacatca gcacacttta ctgaagcttc cattctgaca gagcaggata ttattcagca
    32581 agaacgagaa atgtaccaag atgatccaga ttcgtgttta ttcttttcaa ctttagcgaa
    32641 tttgtatcct ggtacacctt tagcaactga tatagttgga agtgaggagt ccatttccca
    32701 aatcaatcta actaatttgc aagaaaattt tacaaagttt tacaaacctg taaacatgtc
    32761 tctgttttta gttggtaatt ttgatgtgga gcgagtacag gactattttg aaagcaaaga
    32821 actgaaagat tcagattttc aggaagtagc aagagaaaag ttgtttttac agcctgtaaa
    32881 gccaacagat agtatgagaa tggaagtatc ttctcccaaa ctagcgattg gagttagagg
    32941 taagcgagaa gtttctgaag cggattgcta tcgacatcat attttattaa aattattgtt
    33001 tgcaatgatg tttggttgga cttcggatcg ttttcaaaaa tgttatgaat caggtaaaat
    33061 tgatgcatcc ttatctctgg aagttgaagt aacaagtcgc tttcattttg tcatgttgac
    33121 aatggatacg aaagagccag ttgctttgtc tcatcaattt aggaaggcta ttcgtaattt
    33181 tacaaaggat ttagatatta cagaggaaca tttagatatt atcaaaagag agatgtttgg
    33241 cgaatttttc agtagcatga actctcttga atttattgca acgcaatatg atgcttttga
    33301 aaatggtgag acaatttttg atttgccgaa aattttacag gaaattactt tagaggatgt
    33361 ccttgatgct ggacatcatt taatagatga tggtgacata gttgatttta caatattccc
    33421 atcgtagtaa cctattataa tagacactag aaagaaggga tgacaagtat gagaaaaaaa
    33481 acaattggag aggttttacg attagctaga atcaatcagg gattgagttt agatgaattg
    33541 cagaaaaaga cagaaatcca gttagatatg ttggaagcaa tggaagcaga cgatttcgat
    33601 caacttccaa gtccttttta cacgcgttct ttcttgaaaa aatatgcatg ggctgttgag
    33661 ttagatgacc aaattgtttt ggatgcttat gattctggga gtatgattac ttatgaggaa
    33721 gtagatgttg atgaagatga gttgacaggt cgtagacgtt caagtaagaa aaagaagaaa
    33781 aaaacatcat ttttaccttt attttatttt atcctttttg ctttatcgat tttaattttt
    33841 gtgacttatt atgtttggaa ctatattcaa actcaaccag aggagccttc tctttctaat
    33901 tacagtgtgg ttcaatcaac aagttcaact agctctgttc cccactcctc aagtagtagt
    33961 tcttctagta tagaatcagc tataagtgta tcaggcgaag gaaatcatgt agaaatcgct
    34021 tataagacaa gtaaggaaac agttaaattg caattggcag tttcagatgt tacaagttgg
    34081 gtcagtgttt cagaaagcga acttgagggc ggtgtaacct tatcgccaaa gaagaaaagt
    34141 gcagaagcaa cagttgcaac taaaagtcct gtaacaatta cgttaggtgt tgtaaaaggt
    34201 gttgatttga cagtagataa tcagactgtt gatttatcga aattaacagc tcagactgga
    34261 caaatcactg taacctttac taaaaattaa ggaaaaacga atgaaaaaag aacaaattcc
    34321 caatctctta acaataggtc gaattctctt tatacctatt tttatcttta ttttaacgat
    34381 aggaaattcg atagagagtc atatagttgc agctattatc tttgctgttg ccagtattac
    34441 cgactattta gatggatatt tagctcgtaa atggaatgtg gtcagtaatt ttggtaaatt
    34501 tgcagatcct atggcggata agttactagt tatgtcggct tttattatgt tgattgagtt
    34561 aggtatggct ccggcttgga ttgttgcagt gattatctgt cgtgagttag ctgtgacagg
    34621 tttaaggctt ttattggttg aaactggtgg aacaatttta gcagcagcaa tgcctggaaa
    34681 aattaaaact tttagtcaga tgtttgccat tattttcttg ctattacatt ggactttgct
    34741 tggtcaagtt ctactttatg tagccttatt tttcactatc tactctggct atgactattt
    34801 caagggtagt gcctatgtat ttaaagggac atttggttcg aaatgaaatc aataattgat
    34861 gtaaaaaatc tttcttttcg ctataaagaa aatcagaact actacgatgt gaaggatatt
    34921 acgtttcacg tgaaacgtgg agaatggctt tcgattgtag ggcataatgg tagtggtaaa
    34981 tcaacgacgg ttcgattaat tgatggctta ctggaagcag aatccggaga gattgtaatt
    35041 gatggccaac gtttgactga ggaaaatgtt tggaatatac gtcgtcaaat cggtatggtt
    35101 tttcaaaatc cagacaatca atttgttgga gcgactgttg aagatgatgt tgcttttggt
    35161 ttggaaaatc agggactttc tcgtcaagaa atgaaaaaga gagtggaaga agctctggct
    35221 ttagttggca tgttggactt taaaaagaga gagccagcgc gtctatcagg tggccaaaag
    35281 caacgtgtgg ccattgcagg tgttgtagcc ctaagaccag ctattttaat cttagatgaa
    35341 gcaacgagta tgttggatcc tgaggggcgt agagaactta ttgggacagt aaaaggaatt
    35401 cgaaaagact atgatatgac ggtcatttct attacccatg atttggaaga agtcgccatg
    35461 agtgatcgcg tattggtcat gaaaaaaggg gaaattgaat caactagtag tccaagggag
    35521 cttttctctc gaaatgattt agatcaaatt ggattagacg atccttttgc taatcaatta
    35581 aaaaaatctt tgagccagaa tggctatgat ttacctgaaa attatttgac agaaagtgag
    35641 ctagaggata agctatggga attgctctag aaaatgtgaa ttttacatat caagaaggta
    35701 ctcccttagc ttcagcagct ttgtcggatg tttctttgac gattgaagat ggctcttata
    35761 cagctttaat tgggcacaca ggtagtggta aatcaactat tttacaactc ttaaatggtt
    35821 tattggtgcc aagtcaaggg agtgtgaggg tttttgatac cttaatcacc tcgacttcta
    35881 aaaataaaga tattcgtcaa attagaaaac aggttggctt ggtatttcag tttgctgaaa
    35941 atcagatttt tgaagaaacg gttttgaagg acgttgcttt tggaccgcaa aattttggag
    36001 tttctgaaga agatgctgtg aagactgcgc gtgagaaact ggctctggtt ggaattgatg
    36061 aatcactttt tgatcgtagt ccgtttgagc tgtcaggggg acaaatgaga cgtgttgcca
    36121 ttgcaggcat acttgccatg gagccagcta tattagtctt agatgagcca acagctggtc
    36181 tagatcctct agggagaaaa gagttgatga ccctgttcaa aaaactccac cagtcaggga
    36241 tgaccatcgt cttggtaacg catttgatgg atgatgttgc tgaatatgcg aatcaagtct
    36301 atgtaatgga aaagggacgt ttagtaaagg ggggcaaacc aagtgatgtc tttcaagacg
    36361 ttgtttttat ggaagaagtt cagttgggag tacctaaaat tacggccttt tgtaaacgat
    36421 tggctgatag aggcgtgtca tttaaacgat taccgattaa gatagaggag ttcaaggagt
    36481 cgctaaatgg atagtatgat tttagggcgt tatatcccag gggattcgat tgttcaccga
    36541 ttggatccac gtagcaaatt gcttgctatg atgctactga ttttgattgt gttttgggct
    36601 aataacccct tgacgaatct gattcttttt atagcgacag ggatatttat tgccttgtca
    36661 ggagtatctc tttcattttt tattcagggc ttgaagtcta tgtttttctt gattgccttc
    36721 acaactattt ttcaactatt tttcatttct aatgggaatg ttttatttga gttttcgttt
    36781 gtgagaatca cggattatgc tttgcaacaa gctgggatta ttttttgtcg ctttgtattg
    36841 attattttct tttcaacttt gttaacctta acaaccatgc ctttaagttt ggcatcagct
    36901 gtcgaagctt tattagcacc tttaaagcgt gtgaaagttc cagttcatga aattggattg
    36961 atgctgtcta tgagtttgcg ttttgtccca accttgatgg atgatacgac tcggattatg
    37021 aatgcacaga aagctcgtgg agtggatttt ggagaaggaa gcatcgttca aaaagtaaag
    37081 gcgatgattc ccattttgat tcctcttttt gcgacaagtt taaaacgtgc agattccttg
    37141 gctatcgcta tggaagcgcg tggctatcag ggtggaaaag gcagaagtca ataccgacaa
    37201 ttgaaatgga ctctaaagga tacgctgacc attcttgtta ttctcgtact tggttgttgt
    37261 ttatttttct taaaatctta gtagctttca ggaattgata aaaagttact gtaacagttt
    37321 ttgatataaa ggtaggaata tgaaccgttt taaaaaatca aaatatgtca ttattgtttt
    37381 tgtcactgtt ctgcttgtgt cagctctctt agcgacgact tattcaagta caattgtgac
    37441 aaaattagga gatggaatct cattggttga tagagttgta caaaaacctt ttcagtggtt
    37501 tgattctgtc aaatcagatt tggctcattt gacacgaaca tataatgaaa atgaaagttt
    37561 gaagaaacag ctttaccaat tagaagttaa atcaaatgag gtggaaagtt taaagacaga
    37621 aaatgaacaa ctgcgccaat tgcttgatat gaagtctaaa ttgcaagcca caaagacttt
    37681 agcagcagat gttattatgc gttctccggt atcttggaag caggagttga ccttagatgc
    37741 aggtagatca aaaggtgctt ctgagaacat gttagctatt gcaaatggtg gcttgattgg
    37801 gagtgtttca aaagtagagg agaactctac tatagtcaac cttctgacaa atacggaaaa
    37861 tgctgataag atttctgtta aaattcaaca tggctctact acaatttatg gaattattat
    37921 tggctatgac aaggaaaatg acgttcttaa aattagccaa ttaaatagta atagcgatat
    37981 tagtgcggga gataaggtga ctactggtgg attaggaaac tttaacgttg ctgatattcc
    38041 tgttggtgaa gtggttgcca caacgcatag tacagactat ttgacacgag aagtaactgt
    38101 taaattgagt gcagatactc ataatgtaga tgtgatagaa ttagtgggga attcataatg
    38161 agacagttga agcgagttgg agtattttta ttgcttcctt tctttgttct aattgacgcc
    38221 catattagcc agcttctggg ctcatttttc ccccatgtac atttggctag tcattttctt
    38281 tttctatttc tcttatttga gacgatagaa gtatcagagt atctctacct agtctattgt
    38341 tttgttatag gcttggttta tgatgtttac tttttccatc taatagggat tacaactctc
    38401 ttatttatct tattgggagc cttccttcat aaattgaata gtgttatttt gttgaatcgt
    38461 tggacaagaa tgctagctat gattgtgctg acattcctgt ttgaaatggg tagttatctt
    38521 ttggctttta tggtagggtt gacagtagat agcatgtcga tttttatagt ctatagcttg
    38581 gtaccgacga tgattttaaa ttttttatgg attactgttt ttcaatttat ttttgaaaaa
    38641 tattatctat aagaacgaca tataaatgta acaaaggcgt aatatttatt aggccttttt
    38701 ttggtatact agtattgtct ttaaaagaag gagtatctac gtaatatgaa gaaaaaaatc
    38761 ttagcgtcac ttttattaag tacagtaatg gtttctcaag tagctgtttt aacaactgcg
    38821 catgcagaaa cgactgatga caaaattgct gctcaagata ataaaattag taacttaaca
    38881 gcacaacaac aagaagccca aaaacaagtt gaccaaattc aggagcaagt atcagctatt
    38941 caagctgagc agtctaactt gcaagctgaa aatgatagat tacaagcaga atctaagaaa
    39001 ctcgagggtg agattacaga actttctaaa aacattgttt ctcgtaacca atcgttggaa
    39061 aaacaagctc gtagtgctca aacaaatgga gccgtaacta gctatatcaa taccattgta
    39121 aactcaaaat caattacaga agctatttca cgtgttgctg caatgagtga aatcgtatct
    39181 gcaaacaaca aaatgttaga acaacaaaag gcagataaaa aagctatttc tgaaaaacaa
    39241 gtagcaaata atgatgctat caatactgta attgctaatc aacaaaaatt ggctgatgat
    39301 gctcaagcat tgactacgaa acaggcagaa ctaaaagctg ctgaattaag tcttgctgct
    39361 gagaaagcga cagctgaagg ggaaaaagca agtctattag agcaaaaagc agcagctgag
    39421 gcagaggctc gtgcagctgc ggtagcagaa gcagcttata aagaaaaacg agctagccaa
    39481 caacaatcag tacttgcttc agcaaacact aacttaacag ctcaagtgca agcagtatct
    39541 gaatctgcag cagcacctgt ccgtgcaaaa gttcgtccaa catacagtac aaacgcttca
    39601 agttatccaa ttggagaatg tacatgggga gtaaaaacat tggcaccttg ggctggagac
    39661 tactggggta atggagcaca gtgggctaca agtgcagcag cagcaggttt ccgtacaggt
    39721 tcaacacctc aagttggagc aattgcatgt tggaatgatg gtggatatgg tcacgtagcg
    39781 gttgttacag ctgttgaatc aacaacacgt atccaagtat cagaatcaaa ttatgcaggt
    39841 aatcgtacaa ttggaaatca ccgtggatgg ttcaatccaa caacaacttc tgaaggtttt
    39901 gttacatata tttatgcaga ttaatttaca gagggactcg aatagagccc tcttttcagg
    39961 ttttaccgtg acaatcccta ttaaaaatta tatcaaaata gcttgaaaat attggaaaag
    40021 tatggtagaa tgaaaattgt cgtgtgaacg ataatactca ttcttgatga attgtgaagc
    40081 agttgccctt gggtcgtttt gcgagttgaa gtcaagaaga ggaaaaaaac aaaaaggaga
    40141 aatactcatg gcagtaattt caatgaaaca acttcttgag gctggtgtac actttggtca
    40201 ccaaactcgt cgctggaatc ctaagatggc taagtacatc tttactgaac gtaacggaat
    40261 ccacgttatc gacttgcaac aaactgtaaa atacgctgac caagcatacg acttcatgcg
    40321 tgatgcagca gctaacgatg cagttgtatt gttcgttggt actaagaaac aagcagctga
    40381 tgcagttgct gaagaagcag tacgttcagg tcaatacttc atcaaccacc gttggttggg
    40441 tggaactctt acaaactggg gaacaatcca aaaacgtatc gctcgtttga aagaaattaa
    40501 acgtatggaa gaagatggaa ctttcgaagt tcttcctaag aaagaagttg cacttcttaa
    40561 caaacaacgt gcgcgtcttg aaaaattctt gggcggtatc gaagatatgc ctcgtatccc
    40621 agatgtgatg tacgtagttg acccacataa agagcaaatc gctgttaaag aagctaaaaa
    40681 attgggaatc ccagttgtag cgatggttga caccaatact gatccagatg atatcgatgt
    40741 aatcatccca gctaacgatg acgctatccg tgctgttaaa ttgatcacag ctaaattggc
    40801 tgacgctatt atcgaaggac gtcaaggtga ggatgcagta gcagttgaag cagaatttgc
    40861 agcttcagaa actcaagcag attcaattga agaaatcgtt gaagttgtag aaggtgacaa
    40921 cgcttaattt atacaaatag taattaccta ggagggcggg gcttagcccg gctctcctat
    40981 tttcaaaaaa tataggagaa ttaaaatggc agaaattaca gctaaacttg taaaagagtt
    41041 gcgtgaaaaa tctggtgccg gtgttatgga cgctaaaaaa gcgcttgtag aaacagacgg
    41101 tgacatcgaa aaagcgattg aattgcttcg tgaaaaaggt atggctaagg cagctaagaa
    41161 agctgaccgt gttgctgcag aaggtttgac tggtgtttat gttaacggta atgttgcagc
    41221 agttattgaa gtaaacgctg aaactgactt cgttgcaaaa aacgctcaat tcgttgaatt
    41281 ggtaaatact acagctaaag tcattgctga aggaaaacct gctaacaatg aagaagctct
    41341 tgctttgata atgccttcag gtgaaactct tgaagctgca tacgtatctg caacagcaac
    41401 tatcggagag aaaatctcat tccgtcgctt tgcattgatt gaaaaaacag acgcacaaca
    41461 ctttggagca taccaacata acggtggacg tatcggtgtt atttcagttg ttgaaggtgg
    41521 agacgaagca cttgctaaac aattgtcaat gcacatcgca gcgatgaaac caacagttct
    41581 ttcttacaaa gaattggatg agcaattcgt taaagatgag ttggcacaat tgaatcacgt
    41641 tatcgaccaa gacaacgaaa gccgtgcaat ggttaataaa ccagctcttc cacacttgaa
    41701 gtatggatca aaagctcaat taactgatga tgttattgct caagctgaag ctgacatcaa
    41761 agctgaattg gctgcagaag gcaaaccaga aaaaatctgg gacaaaatta ttccaggtaa
    41821 aatggatcgc ttcatgcttg ataacactaa agttgaccaa gcttacacac ttcttgcaca
    41881 agtttacatc atggatgaca gcaagacagt tgaagcatac cttgaatcag ttaacgcttc
    41941 ggtagttgag tttgctcgct ttgaagttgg tgaaggtatc gagaaagctg caaacgactt
    42001 cgaagctgaa gttgcagcta caatggcagc agccttgaat aactaataat agaaaggaag
    42061 caatttgctt ccttttttgt atagggctta tatttttcct gaaattgttt ttcccccagt
    42121 ctcactcgat tagaataatt aaaacaaaaa gccctataat aagggctaag tgcatttagg
    42181 agactatact tcaaattcat agtaagcgcg tcataacaag gtatctatcc taattcccca
    42241 acttccagta tactagataa aaaataatta tcggaggaaa ggtattgtac tatgatgatt
    42301 caactaagtg atttaggtca agttcacatt gtttgtggca agacagatat gaggcaggga
    42361 atagactcat tagcctatgt agttaaaacc cactttgaat tggattcttt ctccggtcaa
    42421 gtctttctct tttgtggtga acgtaaagac cgctttaaag ccctttactg ggatggtcaa
    42481 ggattttggc tactatataa acgctttgag aacggaaaac tgacttggct aagtacagaa
    42541 aaggatgtca aagctctcgc acctgaacaa gtagattggc ttatgaaggg cttttctatc
    42601 actccaaaaa tatagtagat tgaaactaga atagtacacc tctgcttcta aaacattgtt
    42661 agaaatcgat ttgattgtcc tgatcgattt gtcctgttct tatttcattt tactataaat
    42721 ccatcagaaa gtcgtgattt ctattgaaat gaggactttc tttttatact catctgctt
//
LOCUS       DAVHTH010000015        35888 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.015, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000015 DAVHTH010000000
VERSION     DAVHTH010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 35888)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35888)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35888
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.015"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            183..413
                     /gene="blpU"
                     /locus_tag="VVR63_000808"
     CDS             183..413
                     /gene="blpU"
                     /locus_tag="VVR63_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
                     /protein_id="HEU6128841.1"
                     /translation="MNTKKMSQFEIMDTEMLACVEGGGCNWGDFAKAGVGGGAVRGLQ
                     LGIKTRTWQGAATGAAGGAILGGVAYAATCWW"
     gene            1128..3281
                     /locus_tag="VVR63_000809"
     CDS             1128..3281
                     /locus_tag="VVR63_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HEU6128842.1"
                     /translation="MKFGKRHYRPQVDQMDCGVASLAMIFGYYGSYYFLAHLRELAKT
                     TMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDLTFPFVAHVLKEGKLLHYYVVTG
                     QDKDSIHIADPDPGVKLTKLPRERFEEEWTGVTLFMAPSPDYKPYKEQKNGLLSFIPI
                     LVKQRGLIANIVLATLLVIGINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYIL
                     QQILSYAQEYLLLVLGQRLSIDVILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSII
                     DALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTVIIFAFMKPFEKMNR
                     DTMEANAVLSSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQK
                     ALKKVAHLLLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQT
                     AQVANNRLNEVYLVASEFEEKKTVEDLSLMKGDMTFKQVHYKYGYGRDVLSDINLTVP
                     QGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGGVNLNQIDKKALRQYINYLPQQ
                     PYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISG
                     GQRQRIALARALLTDAPVLILDEATSSLDILTEKRIVDNLMALDKTLIFIAHRLTIAE
                     RTEKVVVLDQGKIVEEGKHADLLAQGGFYAHLVNS"
     gene            3294..4643
                     /locus_tag="VVR63_000810"
     CDS             3294..4643
                     /locus_tag="VVR63_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HEU6128843.1"
                     /translation="MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKE
                     MSLSTRATVEPSRILANIQSTSNNRILVNHLEENKLVKKGDLLVQYQEGAEGVQAESY
                     ASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
                     ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTAKSAIETGASLAGQNLAYSLYQSYK
                     SQGEENPQTKVQAVAQVEAQISQLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQ
                     HLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKVTASEDGVLHLNPETSDSSMVAEG
                     ALLAQLYPSLEREGKAKLTAYLSSKYVARIKVGDSVRYTTTHDAGNQLFLDSTITSID
                     ATATKTEKGNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE"
     gene            4813..5520
                     /locus_tag="VVR63_000811"
     CDS             4813..5520
                     /locus_tag="VVR63_000811"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HEU6128844.1"
                     /translation="MSKQLIYSGKAKDIYTTEDENLIISTYKDQATAFNGVKKEQIAG
                     KGVLNNQISSFIFEKLNVAGVATHFVEKLSDTEQLNKKVKIIPLEVVLRNYTAGSFSK
                     RFGVDEGIALETPIVEFYYKNDDLDDPFINDEHVKFLQIAGDQQIAYLKEETRRINEL
                     LKVWFAEIGLKLIDFKLEFGFDKDGKIILADEFSPDNCRLWDADGNHMDKDVFRRGLG
                     ELTDVYEIVWEKLQGLK"
     gene            5577..9302
                     /locus_tag="VVR63_000812"
     CDS             5577..9302
                     /locus_tag="VVR63_000812"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HEU6128845.1"
                     /translation="MDKRIFVEKKADFQVKSESLVRELQHNLGLSSLKSIRIVQVYDV
                     FDLVEDLFAPAEKHIFSEQVTDHVLDEVSVQADLANYAFFAIESLPGQFDQRAASSQE
                     ALLLLGSSSDVTVNTAQLYLVNKDIDATELKAVKNYLLNPVDSRFKDITTGIAKQEFS
                     ESDKTIPKLTFFESYTAEDFARYKAEQGMAMEVDDLLFIQDYFKSIGRVPTETELKVL
                     DTYWSDHCRHTTFETELKHIDFSASKFQKQLQSTYDKYIAMREELGRSEKPQTLMDMA
                     TIFGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRISGAGDITAPISETRAGKLPQQVISKTAAHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKGNVVREKPEAGDVIILLGGK
                     TGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRNGNVTRLIKKSNDF
                     GAGGVCVAIGELADGLEIDLNKVPLKYQGLNGTEIAISESQERMAVVVRPEDVDTFVA
                     ECNKENIDAVVVATVTEKPNLVMHWNGETIVDLERRFLDTNGVRVVVDAKVVDKDVKL
                     PEERQTSAETLESDTLTVLSDLNHASQKGLQTIFDCSVGRSTVNHPLGGRYQLTPTEA
                     SVQKLPVQHGVTHTASVIAQGFNPYVAEWSPYHGAAYAVIEATARLVAAGANWSKARF
                     SYQEYFERMDKQAERFGQPVAALLGSIEAQIQLGLPSIGGKDSMSGTFEELTVPPTLV
                     AFGVTTADSRKVLSPEFKAVGENIYYIPGQALSAEIDFDLIKKNFAQFEASQADHKVT
                     SASAVKYGGVVESLALATFGNYIGAEVTLPELKTALTAQLGGFVFTSPEEIAGVEKIG
                     QTKADFTLTVNGVKLDGHKLDSAFQGTLEEVYPTEFTQAKELEEVPAVVSDVVIKAKE
                     KVEKPVVYIPVFPGTNSEYDSAKAFEKEGAEVNLVPFVTLNEEAIVKSVETMVDNIDK
                     TNILFFAGGFSAADEPDGSAKFIVNILLNEKVRVAIDSFIARGGLIIGICNGFQALVK
                     SGLLPYGNFEDANSTSPTLFYNDANQHVAKMVETRIANTNSPWLAGVQVGDIHAIPVS
                     HGEGKFVVTAEEFAELRDNGQIFSQYVDFNGKPSMDSKYNPNGSVHAIEGITSKNGQI
                     IGKMGHSERYEDGLFQNIPGNKDQHLFASAVKHFTGK"
     gene            9395..10837
                     /locus_tag="VVR63_000813"
     CDS             9395..10837
                     /locus_tag="VVR63_000813"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HEU6128846.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPDAAKLTYFGLHSLQHRGQEGAGI
                     LSNDQGQLKRHRDMGLLSEVFRNPANLDKLTGAGAIGHVRYATAGEASVDNIQPFLFR
                     FHDMQFGLAHNGNLTNAASLKKELEQRGAIFSATSDSEILAHLIRRSHNPSLMGKIKE
                     ALSLVKGGFAYILLFEDKLIAALDPNGFRPLSIGKMANGAVVVSSETCAFEVIGAEWI
                     RDLKPGEIVIIDDEGIQYDSYTDDTQLAICSMEYIYFARPDSNIHGVNVHTARKRMGA
                     QLAREFKHEADIVVGVPNSSLSAAMGFAEESGLPNEMGLIKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVQLLKEAGATEVHVAIGSPALAY
                     PCFYGIDIQTRQELIAANHTVEETRQIIGADSLTYLSIDGLIESIGIETDAPNGGLCV
                     AYFDGDYPTPLYDYEEDYRRSLEEKTSFYK"
     gene            10874..11896
                     /locus_tag="VVR63_000814"
     CDS             10874..11896
                     /locus_tag="VVR63_000814"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HEU6128847.1"
                     /translation="MTNKNAYAQSGVDVEAGYEVVERIKKHVARTERAGVMGALGGFG
                     GMFDLSKTGVKEPVLISGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPL
                     YFLDYVATGKNEPAKLEQVVAGVAEGCVQAGAALIGGETAEMPGMYGEDDYDLAGFAV
                     SVAEKSQIIDGSKVVEGDVLLGLASSGIHSNGYSLVRRVFADYTGEEVLPELEGKKLK
                     EVLLEPTRIYVKAVLPLIKEELVNGIAHITGGGFIENVPRMFADDLAAEIDESKVPVL
                     PIFKALEKYGQIKHEEMFEIFNMGVGLMLAVSPENVERVKELLDEAVYEIGRIVKKEN
                     ESVIIK"
     gene            11893..12438
                     /gene="purN"
                     /locus_tag="VVR63_000815"
     CDS             11893..12438
                     /gene="purN"
                     /locus_tag="VVR63_000815"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HEU6128848.1"
                     /translation="MKKIAVFASGNGSNFQVIAEEFPVEFVFSDHRDAYVLERAKQLG
                     VLSYAFELKEFESKTDYEAALVELLEEHQIDLVCLAGYMKIVGPTLLSAYEGRIVNIH
                     PAYLPEFPGAHGIEDAWNAGVGQSGVTIHWVDSGVDTGQVIKQVRVPRLADDTIDRFE
                     ARIHEAEYRLYPEVVKALFTD"
     gene            12522..13031
                     /locus_tag="VVR63_000816"
     CDS             12522..13031
                     /locus_tag="VVR63_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000894002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEU6128849.1"
                     /translation="MLESKKTTRYVFYVYLMLLTWGILFKFETNPEFIAFFLAPRYIN
                     WIPFSEPLIVDGKIVFAEMLFNLISFIPLGVCFPLIKTNLSSLRIVGTGFLISLLFEC
                     LQYILAIGITDITDLTLNTLGVCVGLLIYQIFIRVFKSQTRKWINILGMLSLGFAYLV
                     LLLLHLIGV"
     gene            13056..14603
                     /gene="purH"
                     /locus_tag="VVR63_000817"
     CDS             13056..14603
                     /gene="purH"
                     /locus_tag="VVR63_000817"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HEU6128850.1"
                     /translation="MTKRVLISVSDKAGIVEFAQELKKLGWEIISTGGTKVALDNAGV
                     DTIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDLDSHLEAAKDNKIELIDLVVVNL
                     YPFKETILKPDVTYADAVENIDIGGPSMLRSAAKNHASVTVVVDPADYAVVLDELAAN
                     GETSYETRQRLAAKVFRHTAAYDALIAEYFTAQVGESKPEKLTLTYDLKQPMRYGENP
                     QQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDSPTVVALKHM
                     NPCGIGQADDIETAWDYAYESDPVSIFGGIVVLNREVDAATAEKMHGVFLEIIIAPSY
                     TDEALAILINKKKNLRILALPFNAQEASEVEAEYTGVVGGLLVQNQDVVKESPADWQV
                     VTKRQPTETEATALEFAWKAIKYVKSNGIIVTNDHMTLGVGPGQTNRVASVRLAIDQA
                     KDRLNGAVLASDAFFPFADNVEEIAKAGIKAIIQPGGSVRDQEFIEAADKYGLTMVFT
                     GVRHFRH"
     gene            14725..15987
                     /gene="purD"
                     /locus_tag="VVR63_000818"
     CDS             14725..15987
                     /gene="purD"
                     /locus_tag="VVR63_000818"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HEU6128851.1"
                     /translation="MKLLVVGSGGREHAIAKKLLESKDVEKVFVAPGNDGMTLDGLEL
                     VNISISEHYKLIDFAKANDIAWTFIGPDDALAAGIVDDFHAAGLKAFGPTRLAAELEW
                     SKDFAKEIMVKYGVSTAAYGTFSDFEEAKAYIEKHGAPIVVKADGLALGKGVVVAETV
                     EQAVEAAHEMLLDNKFGDSGARVVIEEFLEGEEFSLFAFVNGDKFYIMPTAQDHKRAY
                     DGDKGPNTGGMGAYAPVPHLPQSVVDTAVDTIVKPVLEGMIKEGRPYLGVLYAGLILT
                     ADGPKVIEFNARFGDPETQIILPRLTSDFAQNITDILDSKEPNIMWTDKGVTLGVVVA
                     SKGYPLDYERGVELPAKTEGDVITYYAGAKFAENSRALLSNGGRVYMLVTTADTVKEA
                     QASIYQELSQQKIEGLFYRTDIGSKAIK"
     gene            16390..16878
                     /gene="purE"
                     /locus_tag="VVR63_000819"
     CDS             16390..16878
                     /gene="purE"
                     /locus_tag="VVR63_000819"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000805607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HEU6128852.1"
                     /translation="MKPVISIIMGSKSDWATMQKTAEVLDRFGVAYEKKVVSAHRTPD
                     LMFKHAEEARSRGIKIIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGVDSLYSI
                     VQMPGGVPVATMAIGEAGATNAALFALRLLSVEDKSIADALANFAEEQGKIAEESSNE
                     LI"
     gene            16865..17938
                     /gene="purK"
                     /locus_tag="VVR63_000820"
     CDS             16865..17938
                     /gene="purK"
                     /locus_tag="VVR63_000820"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HEU6128853.1"
                     /translation="MSSSKTIGIIGGGQLGQMMAISAIYMGHKVIALDPAADCPASRV
                     AEIIVAPYNDVDALRQLADRCDVLTYEFENVDADGLDAVIKDGQLPQGTDLLRISQNR
                     IFEKDFLSNKAQVTVAPYKVVTSSLDLADIDLSKNYVLKTATGGYDGHGQKVIRSEAD
                     LEAAYALADSADCVLEEFVNFDLEISVIVSGNGKEVTFFPVQENIHRNNILSKTIVPA
                     RISESLVDKAKAMAVRIAEQLNLSGTLCVEMFATDDDVIVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGAPLPVIKLHAPAVMLNVLGQHVEAAEKYVTENSSAHLHMYGKIE
                     AKHNRKMGHVTLISNEPDSVGEF"
     gene            17961..20348
                     /locus_tag="VVR63_000821"
     CDS             17961..20348
                     /locus_tag="VVR63_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001839381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEU6128854.1"
                     /translation="MFEKIKGINIKSGIFEDETKLELFEGNFEGTNPVQNDRASLLFG
                     RNGSGKSTIARGINQLKNGEIGTDRVSFIDKNNNNIVLSDTERKSIFVFNEHYVDQKV
                     KIAQEGLDTIVILGEQVDIDEELDRLRTQLSESQIESQDYYAEYEEYLDEKNEKSPDF
                     WKKEMTDSLKGVGNWAERDREIKGNRAASPVHNNTFQNFVDLQPILDKNELEVEFNNK
                     KARYFSIRDSAVTINNELSLPDINFDSNELSTLLSEKIEEPELNSRDKYLLTLLSDST
                     KGERHLREVKDFFEDEHQKKCPFCTQSVSEDVKVELTNGITKLLSRAVEEHQSALRGK
                     KIDEINQDFSGYEQIDPILIQSYQNSINALNAKFNEINSIIDKKIDNPYNIVELPNIS
                     FSQELSQAEHDIEKINQAIIKHNSEISGIQKLKVDLLQINNELAFYEIQDAYKKFQEK
                     TNKKAICENNYNNSSKRVKDYEKQISDLEDKKLNIDIAVDEINKSLNYIFFSKNRLAI
                     QNQNGKYYLLSRGKSVVPSRVSVGERNALALCYFFTEIIQQRELADAYSHEYFIVIDD
                     PISSFDMENKVGITSYLKYCLTRFFKGNSNTRVLLMTHDKQTIYDFDIFLKEIMESCK
                     EEEGGQKSKYKKLELVSGKLQEFKTSTHDYTELLEIVFGYALGNSTPTSESFVGNAMR
                     KILEAYGSFNYKKGIAELTTDPLIVEKIDKEYRTYFENLMYRLVLNGESHFKDPVKTL
                     SIDFFDTISDEERKKTARDLLVLLYLLDDLHVLKHLEGVSNAENRLEQWKCEILE"
     gene            20521..21819
                     /gene="purB"
                     /locus_tag="VVR63_000822"
     CDS             20521..21819
                     /gene="purB"
                     /locus_tag="VVR63_000822"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HEU6128855.1"
                     /translation="MINRYSRPEMANIWSEENKYRAWLEVEILSDEAWAELGEIPKED
                     VALIRKKADFDIDRILEIEQETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIIADKAKEHKFTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCDKLGIRAQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMITAYENVALWHERDISHSSAERIITPDTTILIDYMLNRFGNIVKNL
                     TVFPENMIRNMNSTFGLIFSQRAMLTLIEKGMTREQAYDLVQPKTAYSWDNQVDFKPL
                     LEADSEVTSRLTQEEINEIFNPIYYTKRVDDIFERLGLGD"
     gene            complement(21874..25812)
                     /gene="strH"
                     /locus_tag="VVR63_000823"
     CDS             complement(21874..25812)
                     /gene="strH"
                     /locus_tag="VVR63_000823"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HEU6128856.1"
                     /translation="MKHEKQQRFSIRKYAVGAASVLIGFAFQAQTVAADGVTPTTTEN
                     QPTIHTVSDSPQSSENRTEETPKAELQPEAPKTVETETPATDKVASLPKTEEKPQEEV
                     SSTPSDKAEVVTPTSAEKETANKKEEEASPKKEEAKEVDSKESNTDKTDKDKPAKKDE
                     AKAEADKPETETGKERAATVNEKLAKKKIVSIDAGRKYFSPEQLKEIIDKAKHYGYTD
                     LHLLVGNDGLRFMLDDMSITANGKTYASDDVKRAIEKGTNDYYNDPNGNHLTESQMTD
                     LINYAKDKGIGLIPTVNSPGHMDAILNAMKELGIQNPNFSYFGKKSARTVDLDNEQAV
                     AFTKALIDKYAAYFAKKTEIFNIGLDEYANDATDAKGWSVLQADKYYPNEGYPVKGYE
                     KFIAYANDLARIVKSHGLKPMAFNDGIYYNSDTSFGSFDKDIIVSMWTGGWGGYDVAS
                     SKLLAEKGHQILNTNDAWYYVLGRNADGQGWYNLDQGLNGIKNTPITSVPKTEGADIP
                     IIGGMVAAWADTPSARYSPSHLFKLMRHFANANAEYFAADYESAEQALNEVPKDLNRY
                     TAESVAAVKEAEKAIRSLDSNLSRAQQDTIDQAIAKLQETVNNLTLTPEAQKEEEAKR
                     EVEKLAKNKVISIDAGRKYFTLDQLKRIVDKASELGYSDVHLLLGNDGLRFLLNDMTI
                     TANGKTYASDDVKKAIIEGTKAYYDDPNGTALTQAEVTELIEYAKSKDIGLIPAINSP
                     GHMDAMLVAMEKLGIKNPQAHFDKVSKTTMDLKNEEAMNFVKALIGKYMDFFAGKTKI
                     FNFGTDEYANDATSAQGWYYLKWYQLYGKFAEYANTLAAMAKERGLQPMAFNDGFYYE
                     DKDDVQFDKDVLISYWSKGWWGYNLASPQYLASKGYKFLNTNGDWYYVIGNHKQDEAY
                     PLSKAVENSGKVPFNQLASTKYPEVDLPTVGSMLSIWADRPSAEYKEEEIFELMTAFA
                     DHNKDYFRANYNALREELAKIPTNLEGYSKESLEALDAAKTALNYNLNRNKQAELDTL
                     VANLKAALQGLKPAATHSGSLDENEVAANVETRPELITRTEEIPFEVIKKENPNLPAG
                     QENIITAGVKGERTHYISVLTENGKTTETVLDSQVTKEVINQVVEVGAPVTHKGDESG
                     LAPTTEVKPRLDIQKEEIPFTTVTRENPLLLKGKTQVITKGVNGHRSNFYSVSTSADG
                     KEVKTLVNSVVAQEAVTQIVEVGTMVTHVGDENGQAAIAEEKPRLEIPSQPAPSTAPA
                     EESKALPQDPAPVVTEKKLPETGTHDSAGLVVAGLMSTLAAYGLTKRKED"
     gene            complement(26127..26843)
                     /locus_tag="VVR63_000824"
     CDS             complement(26127..26843)
                     /locus_tag="VVR63_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001007200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEU6128857.1"
                     /translation="MAIPKYQYIKDELKNKIISGQFSSGDKFYTEAELISMYDVSSIT
                     VVRALNDLAKDGYIVRQQGKGTFISRARKHKLVEFSDIELFNAKDDKVTVLSIERGNK
                     LVYLEKLGLRGDQFYYKIERIRESNGVVYIYHTSYIPEQYINANYPNLEYYSSIYNRF
                     KLDYHIHMNDEHFEEINEIVFPTPEHAASVLGVDEQFPTVLQTKITKLESTGQVLEYS
                     ETYKRSDYYKIKFISCDRDH"
     gene            27191..28978
                     /locus_tag="VVR63_000825"
     CDS             27191..28978
                     /locus_tag="VVR63_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HEU6128858.1"
                     /translation="MTRFEIRDDFYLDGKSFKILSGAIHYFRVPPEDWYHSLYNLKAL
                     GFNTVETYVAWNLHEPREGEFHFEGDLDLEKFLQIAQDLGLYAIVRPSPFICAEWEFG
                     GLPAWLLTKNMRIRSSDPAYIEAVGRYYDQLLPRLVPRLLDNGGNILMMQVENEYGSY
                     GEDKAYLRAIRQLMEECGVTCPLFTSDGPWRATLKAGTLIEEDLFVTGNFGSKAPYNF
                     SQMQEFFDEHGKKWPLMCMEFWDGWFNRWKEPIITRDPKELADAVREVLEQGSINLYM
                     FHGGTNFGFMNGCSARGTLDLPQVTSYDYDALLDEEGNPTAKYLAVKKMMATHFSEYP
                     QLEPLYKESMELDAIPLVEKVSLFETLDSLSSPVESLYPQKMEELGQSYGYLLYRTET
                     NWDAEEERLRIIDGRDRAQLYVDGQWVKTQYQTEIGEDIFYQGKKKGLSRLDILIENM
                     GRVNYGHKFLADTQRKGIRTGVCKDLHFLLNWKHYPLPLDNPEKIDFSKGWTQGQPAF
                     YAYDFTVEEPKDTYLDLSEFGKGVAFVNGQNLGRFWNVGPTLSLYIPHSYLKEGANRI
                     IIFETEGQYKEEIHLTRKPTLKHIKGENL"
     gene            28975..29451
                     /locus_tag="VVR63_000826"
     CDS             28975..29451
                     /locus_tag="VVR63_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEU6128859.1"
                     /translation="MTIVGCRIDGRLIHGQVANLWAGKLNVSRIMVVDDEVVNNDIEK
                     SGLKLATPPGVKLSILPVEKAAANILAGKYDSQRLFIVARKPDRFLGLVEAGVPLETL
                     NVGNMSQTPETRSITRSINVVDKDVEDFHKLAEKGVKLTAQMVPNDPISDFLSLLK"
     gene            29479..30384
                     /locus_tag="VVR63_000827"
     CDS             29479..30384
                     /locus_tag="VVR63_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEU6128860.1"
                     /translation="MIQWWQILLLTLYSAYQICDELTIVSSAGSPVFAGFITGLIMGD
                     VTTGLLIGGNLQLFVLGVGTFGGASRIDATSGAVLATAFSVSQGIDAPLAITTIAVPV
                     AALLTYFDVLGRMTTTFFAHRVDAAIERFDYKGIERNYLLGAIPWALSRALPVFFALA
                     FGGAFVQSVVDFVEAYKWVADGLTLAGRMLPGLGFAILLRYLPVKRNLHYLAMGFGLT
                     AMLTVLYSYVTGLGGAVAGIVGTLPAEVAEKIGFVNNFKGLSMIGISIVGIFLAVLHF
                     KNSQKVAVAAPSTPSESGEIEDDEF"
     gene            30371..31186
                     /locus_tag="VVR63_000828"
     CDS             30371..31186
                     /locus_tag="VVR63_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEU6128861.1"
                     /translation="MTNSNYKLTKEDFNQINKRSLFTFQLGWNYERMQASGYLYMILP
                     QLRKMYGDGTPELKEMMKVHTQFFNTSPFFHTIIAGFDLAMEEKDGVGSKDAVNGIKT
                     GLMGPFAPLGDTIFGSLVPAIMGSVAATMAIAGQPWGIFLWIAVAVAYDIFRWKQLEF
                     AYKEGVNLINNMQSTLTALIDAASVLGVFMMGALVATVINFEISYKLPIGEKMIDFQD
                     ILNQIFPRLLPAIFTAFIFWLLGKKGMNSTKAIGIIIVLALALSALGHFALGM"
     gene            31193..31597
                     /locus_tag="VVR63_000829"
     CDS             31193..31597
                     /locus_tag="VVR63_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU6128862.1"
                     /translation="MTKSLILVSHGRFCEELRGSTEMIMGPQDNIYTVALLPEDGPEE
                     FTAKFEAVIEGLDDFLVFADLLGGTPCNVVSRLIMEGRDIDLYAGMNLPMVIEFINAS
                     LTGADADYKSRAAESIVKVNDLLAGFDDDEDE"
     gene            31850..33016
                     /locus_tag="VVR63_000830"
     CDS             31850..33016
                     /locus_tag="VVR63_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEU6128863.1"
                     /translation="MLHYTKEDLLELGAEITTREIYQQPDVWREAFEFYQAKREEIAA
                     FLQEIADKHDYIKVILTGAGTSAYVGDTLLPYFKEVYDERKWNFNAIATTDIVANPAT
                     YLKKDVATVLVSFARSGNSPESLATVDLAKSLVDELYQVTITCAADGKLALQAHGDDR
                     NLLLLQPAVSNDAGFAMTSSFTSMMLTTLLVFDPTEFAVKSERFEVVSSLARKVLDKA
                     EDVKELVDLDFNRVIYLGAGPFFGLAHEAQLKILELTAGQVATMYESPVGFRHGPKSL
                     INDNTVVLVFGTTTDYTRKYDLDLVREVAGDQIARRVVLLSDQAFGLENVKEVALGCG
                     GVLNDIYRVFPYIVYAQLFALLTSLKVENKPDTPSPTGTVNRVVQGVIIHEYQK"
     gene            33132..34169
                     /locus_tag="VVR63_000831"
     CDS             33132..34169
                     /locus_tag="VVR63_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HEU6128864.1"
                     /translation="MKAYTERVFGNVEGEDVLAYRFETDGGYQLEVMTYGATILRYVA
                     PDKAGNFANVILGFDDFDSYVGNSPKHGASVGPVAGRIAGATFELNGKTYDLEVNNAS
                     NCNHSGSTGWDSSLFEVEEVSDHGLTLYTERTDGTGGFPGNLKIWISYHLEETGAYEI
                     SYKVTTDQDTLVNPTNHSYFNLSGDFTQTIDRHVFQLNTEGIYSIAPDGVPAKTPEAN
                     RDVVKHVYNGTLLKDIFAEEDEQIQLASGLDHPFALPAGHDNAGFLYDQNSGRFLLFK
                     TEAPCFVVYTANFVDESVIIGGQPMLQHNGIALEAQALPDAIHSDLKGQVILKAGQTF
                     TSKTRYELVVK"
     gene            34377..35231
                     /locus_tag="VVR63_000832"
     CDS             34377..35231
                     /locus_tag="VVR63_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEU6128865.1"
                     /translation="MTYEYKSHIYLAETALNVKDLASQTAFYQQVIGLEILSQTETES
                     ILGLGGKVLVQLIQAQESGEVREYYGLYHLAILLPTRKALADVLKHLTDLQIPLVGGA
                     DHGYSEAIYLEDLEGNGIELYRDKPVSTWDIREDGRIIGVTEALAAQDIYELGERVEP
                     FILAEGTRMGHIHLSVKDSRKSSQFYQKVLGLENKFSVPGASWIAAGDYHHHLAVNEW
                     GGKGLASRKQGLPGLAYYVIEVAHKKELLTIAQRAQEVDAPIKWMTSIQLEITDSDGI
                     VTRIRLAR"
     gene            35368..35625
                     /locus_tag="VVR63_000833"
     CDS             35368..35625
                     /locus_tag="VVR63_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HEU6128866.1"
                     /translation="MTNSKYITCLKRSEGQLCGIQKMIEGDRDCADIVTQLTAVKSSV
                     ERVIEMIITENLTECINQPLDDSEAQKERLEKAIRYLIKRK"
BASE COUNT        10259 a         6760 c         8275 g        10594 t
ORIGIN      
        1 gtaaaaagtg attagaaaac atctttttta aaaatagaga tgattttgaa acaaaaaagc
       61 taattcaaga cgtttcgatt ccaattcaag atttggatga aaaaaattaa tagatactgt
      121 tatactaaac ttgtcaagtt tgtaacaaga caaatattaa aaataaaaaa gaggtattcg
      181 ttatgaatac aaaaaagatg tcacaatttg aaattatgga tactgagatg cttgcttgcg
      241 ttgaaggtgg cggatgcaat tggggagatt ttgccaaagc aggtgttgga ggaggagcag
      301 tacgaggtct tcagctagga attaaaacaa gaacatggca aggtgcagca actggtgctg
      361 cgggaggagc tatacttgga ggtgtggcct atgcagcgac atgttggtgg taattatgga
      421 ttttaaaagt tttattattg gtttagtagt tggtatattt ggtccttata tggatgattt
      481 aattagaaaa aaatttttaa agtcttcgga gaagaaaaca gaaaaatctg ttaaaaaata
      541 atcaaaacta taaatgatga atctgaatca aaattatttt gcgcatgtaa agaggagtct
      601 tatagtaacg agtcaaaaaa ggagtaacta tgaatcgtaa tttagaacgg tgttatctat
      661 tctgactagg aatagatcat accagaggta gcttagaaat agcagggaca ttagaaattg
      721 aagtaataaa taggatgtcg taagtgttac tatcaatgat ttatttgttt caagcttgcc
      781 tagggtgaca gtaaaaaatc aatttccttt caatagcata tttttagtgg gcaggactct
      841 tgttctgcct atttttttat ccaaaaagtg cagttgggag ggagataggc tcatttggga
      901 aggaagtcca gtttttgttt agtgattggg gtaagatagt tgttatcaga tgagtttata
      961 ctcttcgaaa atcaaattca aaccacgtca acgtcgcctt gccgtatata tgtgactgac
     1021 ttcgtcagtc ctatctacaa cctcaaaaca gtgttttgag cagcctgcgg ctagtttcct
     1081 agtttgctct ttgattttca ttgagtatta gggaaaagga gatgaatatg aaatttggga
     1141 aacgtcacta tcgtccgcaa gtggatcaga tggactgcgg tgtagcttca ttagccatga
     1201 tttttggcta ctatggtagt tattattttt tggctcactt gcgagaattg gctaagacga
     1261 ccatggatgg gacgacggct ttgggcttgg tcaaggtggc agaggagatt ggttttgaga
     1321 cgcgagccat taaggcggat atgacgcttt ttgacttgcc ggatttgact tttccttttg
     1381 ttgcccatgt gcttaaggaa gggaaattgc tccactacta tgtggtgact gggcaggata
     1441 aggatagcat tcatattgcc gatccagatc ccggggtgaa gttgactaaa ctgccacgtg
     1501 agcgttttga ggaagaatgg acaggagtga ctctttttat ggcacctagt ccagactata
     1561 agccttataa ggaacaaaaa aatggtctgc tctcttttat ccctatatta gtgaagcagc
     1621 gtggcttgat tgctaatatc gttttggcaa cactcttggt aatcgggatt aacattgtgg
     1681 gttcttatta tctgcagtct atcattgata cctatgtgcc agatcagatg cgttcgacac
     1741 tagggattat ttctattggg ctagtcatcg tctacatcct ccagcaaatc ttgtcttacg
     1801 ctcaggagta tctcttgctt gttttggggc aacgcttgtc gattgacgtg attttgtcct
     1861 atatcaagca tgtttttcac ctccctatgt ccttctttgc gacacgcagg acaggggaga
     1921 tcgtgtctcg ttttacagat gctaacagta tcatcgatgc gctggcttcg accatccttt
     1981 cgattttcct agatgtgtca acggttgtca ttatttccct tgttctattt tcacaaaata
     2041 ccaatctctt tttcatgact ttattggcgc ttcctatcta cacagtgatt atctttgcct
     2101 ttatgaagcc gtttgaaaag atgaatcggg ataccatgga agccaatgcg gttctgtctt
     2161 cttctatcat tgaggacatc aacggtattg agactatcaa gtccttgacc agtgaaagtc
     2221 agcgttacca aaaaattgac aaggaatttg tggattatct gaagaaatcc tttacctata
     2281 gtcgagcaga gagtcagcaa aaggctctga aaaaggttgc ccatctcttg cttaatgtcg
     2341 gcattctctg gatgggggct gttctggtca tggatggcaa gatgagtttg gggcagttga
     2401 ttacctataa taccttgctg gtttacttta ccaatccttt ggaaaatatc atcaatctgc
     2461 aaaccaagct tcagacagcg caggttgcca ataaccgtct aaatgaagtg tatctagtag
     2521 cttctgagtt tgaggagaag aaaacagttg aggatttgag cttgatgaag ggagatatga
     2581 ccttcaagca ggttcattac aagtatggct atggtcgaga cgtcttgtcg gatatcaatt
     2641 taaccgttcc ccaagggtct aaggtggctt ttgtggggat ttcagggtca ggtaagacga
     2701 ctttggccaa gatgatggtt aatttttacg acccaagtca aggggagatt agtctgggtg
     2761 gtgtcaatct caatcagatt gataaaaaag ccctgcgcca gtacatcaac tatctgcctc
     2821 aacagcccta tgtctttaac ggaacgattt tggagaatct tcttttggga gccaaggagg
     2881 ggacgacaca ggaagatatc ttacgggcgg tcgaattggc agagattcga gaggatatcg
     2941 agcgcatgcc actgaattac cagacagaat tgacttcgga tggggcaggg atttcaggtg
     3001 gtcaacgtca gagaatcgct ttggcgcgtg ctctcttgac agatgcgccg gtcttgattt
     3061 tggatgaggc gactagcagt ttggatattt tgacagagaa gcggattgtc gataatctca
     3121 tggctttgga caagaccttg attttcattg ctcaccgctt gactattgct gagcggacag
     3181 agaaggtagt tgtcttggat cagggcaaga ttgtcgaaga aggaaagcat gctgatttgc
     3241 ttgcacaggg tggcttttac gcccatttgg tcaatagcta gaaagaggag aggatgaaac
     3301 cagaattttt agaaagtgcg gagttttata atcgtcgtta ccataatttt tccagtagtg
     3361 tgattgtacc catggccctt ctgcttgtgt ttttacttgg ctttgcaact gttgcagaga
     3421 aggagatgag tttgtccact agagctactg tcgaacctag tcgtatcctt gcaaatatcc
     3481 agtcaactag caacaatcgt attcttgtca atcatttgga agaaaataag ctggttaaga
     3541 agggggatct tttggttcaa taccaagaag gggcagaggg tgtccaagcg gagtcctatg
     3601 ccagtcagtt ggacatgcta aaggatcaaa aaaagcaatt ggagtatctg caaaagagcc
     3661 tgcaagaagg ggagaaccac tttccagagg aggataagtt tggctaccaa gccacctttc
     3721 gcgactacat cagtcaagca ggcagtctta gggctagtac atcgcaacaa aatgagacca
     3781 tcgcgtccca gaatgcagca gctagccaaa cccaagccga aatcggcaac ctcatcagtc
     3841 aaacagaggc taaaattcgc gattaccaga cagctaagtc agctattgaa acaggtgctt
     3901 ccttggccgg tcagaatcta gcctactctc tttaccagtc ctacaagtct cagggcgagg
     3961 aaaatcccca aactaaggtt caggcagttg cacaggttga agcacagatt tctcagttag
     4021 aatctagtct tgctacttac cgtgtccagt atgcaggttc aggtacccag caagcctatg
     4081 cgtcagggtt aagcagtcaa ttggaatccc ttaaatccca acacttggca aaggttggtc
     4141 aggaattgac ccttctagcc cagaaaattt tggaggcaga gtcaggtaag aaggtacagg
     4201 gaaatctttt agacaagggg aaagttacgg cgagtgagga tggggtgctt catcttaatc
     4261 ctgagaccag tgattctagc atggttgcag aaggtgccct actagcccaa ctttatccat
     4321 ctttggaaag agaagggaaa gccaaactca cagcttatct aagttcaaaa tatgtagcaa
     4381 gaatcaaggt cggtgattct gttcgctata ctacgactca tgatgccggg aatcaacttt
     4441 tcctagattc tactattaca agtattgatg cgacagctac taagactgag aaagggaatt
     4501 tctttaaaat cgaggcggag actaatctaa cttcggagca ggctgaaaaa cttaggtacg
     4561 gggtggaagg ccgcttgcag atgattacgg gcaagaaaag ttacctacgt tattatttgg
     4621 atcaattttt gaacaaagag taatgttcgt gtttttagag ttaaataatt tttaaactgt
     4681 gagaaagatt cttcttgcag ttttttcttt acaatttttg aaaaacatct actatttatt
     4741 cggttaaatt cttgtgtttt ttggtttttt gtggtaaaat gtgctcaagt aatacgaaag
     4801 gcgaacttta aaatgtcaaa acaattgatc tattcgggaa aagctaaaga tatctataca
     4861 actgaggatg aaaatcttat tatttcaact tacaaggacc aggcgactgc tttcaacggt
     4921 gtcaagaagg agcagattgc aggtaaggga gtcttgaata atcagatctc atcttttatt
     4981 tttgagaaat taaatgtggc tggtgtggcg actcactttg tggagaaact ttcagacacg
     5041 gaacaactca ataaaaaggt taagattatt cctttggaag tcgtgctccg caactatact
     5101 gctggttcct tttcaaaacg ttttggtgtg gatgagggaa tcgccttgga gactccgatt
     5161 gtcgaatttt actacaaaaa tgatgatttg gatgatccat ttatcaatga tgagcatgtg
     5221 aaattcctac agattgcggg tgaccagcag attgcctact tgaaggaaga aacgcgtcgt
     5281 atcaatgaac tattgaaagt ctggtttgct gagattgggc ttaaattgat tgactttaag
     5341 ctagagttcg gttttgacaa ggatggcaag attatcttgg cagacgaatt ttcaccagat
     5401 aactgccgct tgtgggacgc tgatggcaac cacatggata aggatgtttt ccgtagagga
     5461 ttgggagaac taaccgacgt ttatgagatt gtttgggaaa agttgcaggg tttaaaataa
     5521 caacctcaag gctgtttggg aatattgcaa gagctgaaat aaaggaataa gaattgatgg
     5581 ataaacgtat ttttgttgaa aaaaaggctg attttcaggt caagtcagag agtttggtta
     5641 gagagctcca gcacaacttg ggactgtcaa gcttgaaaag tattcgtatt gtgcaagtat
     5701 atgatgtatt tgacttggtt gaggacttgt ttgcacctgc agagaagcac attttctctg
     5761 agcaggtaac cgaccatgtt ttagatgaag tatctgtgca ggcggatctt gctaactatg
     5821 ctttctttgc cattgaaagt ctaccagggc agtttgacca gcgtgcagct tcgtcacagg
     5881 aagccttgct tttgttggga agttcgagtg acgtgacagt caacacagcc caactttact
     5941 tggtgaataa agatattgat gcgactgagt tgaaagctgt caaaaactac ctgctcaatc
     6001 cagttgattc tcgtttcaag gatatcacga cagggattgc caagcaggag ttttcagagt
     6061 cagacaagac cattccaaaa ttgactttct ttgaaagcta tacagcagaa gattttgctc
     6121 gctacaaggc cgaacaaggg atggccatgg aagtggatga tttgctcttt atccaagact
     6181 actttaagtc aatcgggcgc gtgccaactg agactgaact taaggttttg gacacttact
     6241 ggtctgacca ctgccgtcat acgacttttg agacagagtt gaaacacatc gacttttcag
     6301 cttctaaatt tcaaaagcaa ttgcagtcaa cctatgacaa gtatattgcc atgcgcgagg
     6361 aattaggtcg gtctgaaaaa ccacaaacct tgatggatat ggcgactatt ttcggtcgtt
     6421 atgagcgtgc taatggacga ttggatgata tggaagtctc tgacgaaatc aatgcctgct
     6481 cagttgaaat tgaagtggac gttgatggtg tcaaggaacc ttggctcctc atgtttaaaa
     6541 acgaaaccca caaccatcca acagaaattg agccatttgg tggagcggct acctgtattg
     6601 gtggagctat tcgtgatccg ttgtcaggcc gttcctatgt ttaccaagcc atgcgtattt
     6661 caggtgctgg tgatattaca gcaccgattt cggaaactcg cgctgggaaa ttgccacaac
     6721 aagtcatttc taaaacagca gctcatggtt attcttcata tggtaaccag attgggcttg
     6781 ccacaaccta cgttcgtgaa tacttccacc caggctttgt agctaaacgt atggaacttg
     6841 gtgccgttgt tggtgcggct cccaagggca atgttgtccg tgaaaaacct gaagcaggtg
     6901 atgtgatcat ccttctcgga ggtaaaacag gtcgtgatgg tgtcggtggt gcgacgggct
     6961 cttctaaggt tcaaacagtt gagtctgtag agactgctgg tgctgaggtt caaaaaggaa
     7021 atgccatcga agaacgcaag attcagcgcc tcttccgtaa tggcaatgtc actcgtctga
     7081 tcaagaagtc caatgacttt ggggcaggcg gtgtctgtgt ggctatcggt gaattggcag
     7141 acggtcttga aatcgacctc aacaaggtgc ctcttaaata ccagggcttg aatggtacag
     7201 aaattgccat ctctgaatca caagaacgga tggcggtcgt ggttcgtcct gaagatgtgg
     7261 ataccttcgt tgccgaatgt aacaaagaaa atattgatgc tgttgtggtg gcgacagtaa
     7321 ctgaaaaacc aaatcttgtc atgcactgga atggtgagac aatcgttgac ttggagcgtc
     7381 gtttccttga caccaatggt gtgcgcgtgg ttgtcgatgc caaagttgtg gacaaggatg
     7441 tcaaactccc agaagagcgt caaacatctg ctgaaacact ggaatcagat acccttacgg
     7501 ttctatctga cctcaaccat gcaagtcaaa aaggattaca gactatcttt gactgctctg
     7561 ttggacgctc aacggttaat cacccacttg gtggtcgtta ccaactcaca ccaactgagg
     7621 catctgtgca gaaattgcca gttcaacacg gtgtgactca tactgcgtcg gtcattgctc
     7681 aaggtttcaa cccatatgta gctgaatggt ctccatacca cggtgctgct tatgcggtta
     7741 tcgaagcaac tgctcgtttg gtggctgctg gtgccaactg gtctaaggct cgtttctctt
     7801 accaagaata tttcgagcgg atggacaagc aagcagagcg ttttggtcag ccagtagccg
     7861 cccttctagg ctctattgaa gcacaaattc agcttggctt gccatctatc ggtggtaagg
     7921 actccatgtc tggtaccttt gaagaattga ccgttccgcc aaccttggtt gcctttgggg
     7981 tgacgacggc agatagccgt aaggtgctct ctccagaatt taaagctgtt ggggaaaata
     8041 tctactacat cccaggtcaa gccctctctg cagagattga ttttgacttg attaagaaaa
     8101 attttgctca gtttgaagca agccaagctg accataaagt gacatctgca tcagctgtca
     8161 aatacggtgg tgtagttgaa agtttggctc ttgctacctt tggaaactat attggtgcag
     8221 aggtgacctt gcctgaactt aaaacagctt tgacagctca attaggcggc tttgtcttca
     8281 catctcctga agaaattgct ggagtagaga agattggaca aacgaaagca gactttacac
     8341 tgactgtcaa cggtgtgaag ctagatggac acaagcttga cagtgcattt caagggacat
     8401 tggaagaagt ttacccaaca gaatttaccc aagcgaaaga actagaagaa gtaccagctg
     8461 tggtatcaga tgttgtgatt aaagccaaag aaaaggttga aaaacctgtg gtttacatcc
     8521 cagtctttcc aggaaccaac tcagaatatg attcagctaa ggccttcgaa aaagaaggtg
     8581 cagaggtcaa tttggtgcca ttcgtgacct tgaatgaaga agctattgtc aagtcagttg
     8641 aaactatggt tgacaatatc gacaagacta atattctctt ctttgccggt ggattctcgg
     8701 ctgcggatga accagatggt tcagctaagt ttatcgtcaa tatcctgctt aatgaaaaag
     8761 tgcgtgtggc tattgatagc tttatcgccc gtggtggctt gattatcggt atttgtaatg
     8821 gattccaagc cttagtcaaa tcgggtctcc taccatacgg aaactttgaa gatgctaaca
     8881 gtactagtcc aaccctcttc tacaatgatg ccaaccaaca cgtggccaag atggtggaaa
     8941 ctcgtattgc caataccaac tcaccatggt tggctggtgt gcaagtgggc gatatccacg
     9001 ctattcctgt ttcgcacggt gaagggaagt ttgtcgtgac ggctgaggaa tttgcagagc
     9061 tccgtgacaa tggacaaatt ttcagccaat acgttgactt taacggtaaa ccaagtatgg
     9121 attctaagta caatccgaat ggttctgtcc atgccatcga aggaattacc agcaagaatg
     9181 gtcaaatcat cggtaagatg ggccactcag aacgttatga ggatggtctt ttccaaaata
     9241 tcccaggcaa taaagaccaa cacctgttcg catcagcggt taaacatttc actggaaaat
     9301 aagacttaca gattttctaa tagatagtat cagtaatgta aaagtcatgt aaatctagct
     9361 cttgatgatt acaaatgaaa attaggtata aaaaatgaca tacgaagtaa aatctcttaa
     9421 tgaagaatgt ggtgttttcg gtatttgggg acatccagat gctgctaagt tgacctattt
     9481 tggactccac agtcttcaac accgtggtca ggagggggca ggaatcctct ccaatgatca
     9541 aggacaactg aagcgccatc gtgacatggg gcttttatca gaagttttca gaaatccagc
     9601 caatttggat aaattgacag gagctggtgc gattgggcat gtgcgttatg cgactgctgg
     9661 cgaagcttct gttgataaca tccagccctt cctcttccgt tttcacgata tgcagtttgg
     9721 cttggctcat aatggaaatc tgaccaatgc agcctctctc aagaaagaac tggaacaaag
     9781 aggagcaatt ttcagcgcga cttcggactc tgaaatcttg gctcacctca ttcgtcgcag
     9841 tcataatcct agcctgatgg gtaaaatcaa ggaagcgctc agccttgtca aaggtggttt
     9901 tgcctatatc ttgctgtttg aggacaagtt gattgcggct cttgacccta atggctttcg
     9961 tccgctttct atcgggaaaa tggccaacgg agcggtggtt gtttcctctg aaacctgtgc
    10021 ttttgaggtc attggtgccg agtggattcg tgatttgaag ccaggtgaga ttgtgatcat
    10081 tgatgacgag ggcattcagt atgacagcta tacagatgat actcagttgg cgatttgttc
    10141 tatggagtat atctactttg ctcgccctga ttctaatatc cacggtgtca atgtccatac
    10201 ggcacgtaag agaatgggag cgcaattggc gcgagaattt aagcatgagg cagatattgt
    10261 agttggtgtg cccaattctt ccctaagcgc ggctatggga tttgcggaag aatcaggctt
    10321 accaaatgaa atgggtctga tcaaaaacca atacacccag cgaactttta tccaaccgac
    10381 tcaagaattg cgggagcaag gagtgcggat gaaactgtct gctgtttcgg gtgttgtcaa
    10441 aggcaaacgt gtggtcatgg tggatgattc cattgtacgt ggaacaacct ctcgtcgtat
    10501 cgttcagctc ttgaaagaag cgggtgcgac tgaggttcac gttgccattg gaagtcctgc
    10561 actagcgtat ccatgtttct acgggattga tatccagacc cgtcaggagc tgattgcagc
    10621 caatcatacg gtcgaagaaa ctcgccaaat cattggtgcg gacagtctga cttatctttc
    10681 aattgatggc ttgattgagt cgattggtat cgaaacagat gcgccgaacg gtggtctctg
    10741 tgtcgcttac tttgacggtg actacccaac gcctctctat gactacgaag aagactatcg
    10801 tagaagtttg gaagaaaaga ccagttttta caagtaggcg acagattctc cattaaagaa
    10861 aaggaaaaaa caaatgacaa ataaaaatgc atatgcccag tcgggtgtgg atgttgaagc
    10921 gggttatgaa gttgttgaac ggattaaaaa gcacgtggcc cgtacggagc gtgcaggtgt
    10981 catgggagct cttggtggct ttggtggtat gtttgacctt tccaagactg gggttaaaga
    11041 acccgtcttg atttcaggga ctgacggtgt cggaaccaag ctcatgttgg ctatcaagta
    11101 cgacaagcac gataccatcg ggcaggactg tgtggccatg tgtgtcaacg acatcattgc
    11161 tgcaggtgcg gaacccctct attttctcga ctacgtagcg acagggaaga atgaaccagc
    11221 taagctagaa caagtggttg ctggtgtggc agaaggttgt gtgcaggctg gtgctgccct
    11281 catcggtggg gaaacggctg aaatgccggg catgtacggc gaagacgact atgacttggc
    11341 tggttttgcg gtcagtgtgg ctgaaaaatc tcaaatcatt gacggttcaa aggtggtaga
    11401 gggagatgtt cttctcggac ttgcttcaag tgggattcac tcaaatggtt actctttggt
    11461 tcgtcgtgtc tttgcggatt acacaggtga ggaagtccta ccagaattgg aaggcaagaa
    11521 acttaaggaa gttctacttg agccgactcg tatctatgtc aaggctgtct tgccgctcat
    11581 caaagaagag ttggtcaacg gcattgccca catcacaggt ggtggcttta tcgaaaatgt
    11641 ccctcgtatg tttgcagatg acctagctgc tgaaattgat gaaagcaaag ttccagtgct
    11701 tccaattttc aaagcccttg aaaaatatgg tcagattaaa cacgaagaaa tgtttgaaat
    11761 cttcaatatg ggtgtgggac ttatgttggc ggtcagccct gaaaatgtag agcgtgtaaa
    11821 agaattgttg gatgaagcag tctatgaaat tggtcgcatc gtcaagaaag aaaacgaaag
    11881 tgtcattatc aaatgaaaaa aatagcggtt tttgcctctg gtaatggctc aaattttcag
    11941 gtgattgccg aagaatttcc agtggagttt gtcttttcag accatcgtga tgcctatgtg
    12001 cttgagcgtg caaagcagct cggcgttctg tcctatgctt ttgaactcaa ggagtttgag
    12061 agcaagacag actacgaagc agcccttgtc gaactcttgg aagaacacca gattgacttg
    12121 gtttgcctag caggctacat gaaaatcgtt ggaccaacct tattgtcggc ttatgaaggt
    12181 cggattgtca acattcatcc agcctacttg ccagaatttc caggagctca tgggattgag
    12241 gatgcttgga atgctggcgt gggtcagtct ggtgtgacca ttcactgggt ggattcgggt
    12301 gtggatacag gccaggtcat caaacaggtt cgtgtgccac gactagctga tgataccatt
    12361 gacagatttg aagctcgcat ccatgaagca gagtacaggt tgtatccgga agtagtgaag
    12421 gctctattta cagattgact ttttgatgat tcatatgata tctttgattt taaattggag
    12481 tcagtgtttg ttgaagacgg cttcaaacgg aggtatttgt aatgttagaa tctaaaaaaa
    12541 caactcgata tgtattttat gtctatctga tgttattaac ttggggaatc ttatttaagt
    12601 ttgaaacaaa tcctgaattt atagcatttt tcttagctcc aaggtatatc aattggattc
    12661 cattttcaga accactaata gtcgatggaa aaattgtttt tgctgaaatg ttatttaatc
    12721 tgatttcctt tattccatta ggtgtttgtt tccctttgat aaaaactaat ttatctagtt
    12781 taagaatagt cgggacaggt ttcttgatta gtttattgtt tgagtgctta cagtatattt
    12841 tagcaatagg tataacagat ataacggatt tgactttaaa tacgctaggt gtctgtgtag
    12901 gcttactgat ttatcaaatt tttataagag tgttcaaatc acagactaga aaatggatca
    12961 atatcttagg tatgcttagc cttggttttg cttatcttgt tttactgtta ctgcatttaa
    13021 ttggtgttta actaatgatt aaaaaggaga atataatgac taaacgcgtc ttaatcagcg
    13081 tctcagacaa agcgggcatt gttgaatttg cccaagaact caaaaaactt ggttgggaga
    13141 ttatctcaac aggtggaact aaggttgccc ttgataatgc tggggtggat accattgcta
    13201 tcgatgatgt gactggtttc ccagaaatga tggacggtcg tgtgaagacc ctccacccaa
    13261 atatccacgg agggcttctc gctcgtcgtg acttggatag ccacttggaa gcggctaagg
    13321 acaacaagat tgagctcatt gaccttgtgg tggtcaacct ttacccattt aaggaaacta
    13381 tccttaaacc agatgtgact tatgctgatg cagttgaaaa tatcgatatt ggtgggccgt
    13441 ctatgcttcg ttcagcagcg aaaaatcatg ccagtgttac agttgtggta gatcctgctg
    13501 actacgctgt ggttttggac gaattggcag caaacggcga aacctcttat gaaactcgcc
    13561 aacgtttagc agccaaagta tttcgtcaca cagcggctta tgacgccttg attgcagaat
    13621 acttcacagc tcaagtgggt gaaagcaagc ctgaaaaact cactttgact tatgacctca
    13681 agcaaccaat gcgttacggt gagaatcctc aacaagacgc ggacttttac cagaaagctt
    13741 tgcctacaga ttactctatt gcttcagcca aacagctcaa cgggaaagaa ttgtcattta
    13801 ataatatccg tgatgcagat gctgctatcc gtatcatccg tgacttcaaa gatagtccaa
    13861 ccgttgtggc tctcaaacac atgaatccat gtggaattgg tcaagctgat gacatcgaga
    13921 ctgcttggga ctacgcttat gagtctgacc cagtatctat ctttggtggg attgtcgtcc
    13981 tcaaccgtga ggtggatgct gcgacagctg agaagatgca cggcgttttc ctcgaaatca
    14041 tcattgcacc aagctatacg gatgaagcgc tagctatttt gatcaataaa aagaaaaact
    14101 tgcgtatcct tgccttgcca tttaatgctc aagaggctag cgaagtggaa gcagaataca
    14161 caggtgtagt cggtggactt ctcgtgcaaa atcaagacgt ggtcaaggaa agcccagctg
    14221 actggcaagt ggtgaccaaa cgtcagccaa ctgagacaga agcgactgct cttgagttcg
    14281 cttggaaggc tatcaagtac gtcaaatcaa atggtattat cgtgaccaac gaccacatga
    14341 cacttggtgt tggtccaggt caaaccaacc gtgtggcttc tgttcgcctt gccattgacc
    14401 aagccaaaga tcgtctgaac ggggcggtcc ttgcttcaga tgccttcttc ccatttgcgg
    14461 ataacgtgga agaaatcgcc aaagcaggaa ttaaggccat catccagccc ggtggctctg
    14521 tccgtgacca agaattcatc gaagcagcgg ataaatacgg cttgactatg gtctttacag
    14581 gtgtgagaca ttttagacat taagaagata aaagggaaga aaacagtttc tttccttttt
    14641 tggcttaaaa tgctaactga aacaagatta aaacgaactt ttttgatata atgttggtaa
    14701 ataattcgca aaagaggttg aggaatgaaa ctgcttgttg tcggttctgg tggtcgtgag
    14761 catgcgattg ctaaaaagtt acttgaatca aaagacgtgg aaaaagtctt tgtagctcct
    14821 gggaatgacg gtatgactct ggatggtctg gaattggtaa atatatctat ttccgaacat
    14881 tataaattga ttgacttcgc aaaggccaac gatattgctt ggacctttat cggtccagat
    14941 gacgcccttg cggctggtat cgtggatgat ttccatgcag ctggtctcaa agcctttggt
    15001 ccgacaagat tggcagcgga gctggagtgg tccaaggatt tcgccaagga aatcatggtc
    15061 aaatatggtg tttcgacagc agcctatggc acattttcag atttcgagga agcaaaggcc
    15121 tatatcgaaa agcatggtgc gcctatcgta gtcaaggcgg atggcttggc gcttgggaag
    15181 ggtgtcgtcg ttgctgagac ggttgagcaa gcggtcgaag ccgctcatga gatgcttttg
    15241 gacaataaat ttggtgactc aggtgcgcgc gtggttattg aggaattcct tgaaggagag
    15301 gaattttcac tctttgcctt tgtcaatggt gataagttct acatcatgcc aacggctcag
    15361 gaccacaaac gtgcctacga tggcgacaaa gggcctaaca cgggtggtat gggtgcctat
    15421 gcgccagttc cacacttacc acagagtgta gttgatacag cggttgacac cattgtcaag
    15481 ccagttctag aagggatgat taaagaaggt cgcccttatc tgggagttct ttacgcaggg
    15541 cttatcctga cagctgatgg accgaaagtc attgagttca acgctcggtt cggagatcca
    15601 gaaactcaga ttatcttgcc tcgcttgacc tctgactttg ctcaaaatat cacagatatc
    15661 ctggatagca aggagccaaa tatcatgtgg acggacaagg gtgtgactct gggtgtggtt
    15721 gtcgcatcca agggctaccc gctagactat gaaaggggcg ttgagttgcc agccaagaca
    15781 gaaggcgatg tcatcaccta ctatgcaggg gctaagtttg cggaaaatag cagagcactg
    15841 ctctcaaacg gcggacgagt ttatatgctc gttaccacag cagataccgt caaagaagcc
    15901 caagccagca tctaccaaga actatcccaa caaaaaatag aaggactctt ctaccgaaca
    15961 gatatcggaa gcaaggcaat taagtaaaga tataagaata acgcgccgta gtcgccaaac
    16021 acgataatgg tcgtcgtggt gaaaagacca gaacagtgaa tgttctggtc agggggaaac
    16081 ttggagaccg taggctcaaa gtttaggaat gaaaccgaag gtttgcttcc gcctccatca
    16141 cctaagacca ttatcaaaaa gaaaaataaa aattcacaaa atacgttaat gatcgtatgg
    16201 tttgcgagcg ttagcgagct aatatagaac aatcaccgcc gttgtgaaag aacgattgga
    16261 tgataatcca atcgttcagg gaaattggaa gaccttgggt ttccaattta ggcatgagac
    16321 acctttggtg gctgctgccg tccctcacaa gctaaggtga ttgttgaaaa agaggaaaaa
    16381 ggagaagaaa tgaaaccagt aatttccatc atcatgggct caaaatccga ctgggcaacc
    16441 atgcaaaaaa cagcagaagt cctagaccgc ttcggtgtag cctacgaaaa gaaagttgtt
    16501 tccgcacacc gtacaccaga cctcatgttc aaacatgcag aagaagcccg tagtcgtggc
    16561 atcaagatca tcatcgcagg tgctggtggc gcagcgcatt tgccaggcat ggtagctgcc
    16621 aaaacaaccc ttccagtcat tggtgtgcca gtcaagtctc gtgctcttag tggagtggat
    16681 tcactctatt ctatcgttca gatgccgggt ggggtgcctg ttgcgaccat ggctatcggt
    16741 gaagctggag cgactaacgc agctctcttt gccctccgtc tcctctctgt agaagataag
    16801 tccattgcgg atgcacttgc caactttgct gaagaacaag gaaaaatcgc agaggagtcg
    16861 tcaaatgagc tcatctaaaa caatcggaat tatcggtggc ggtcaactgg gtcagatgat
    16921 ggccatttct gctatctaca tgggccacaa ggttatcgcg ctggatcctg cggcggattg
    16981 cccggcctct cgcgtggcgg aaatcattgt ggcaccttat aacgatgtgg acgccctccg
    17041 tcagttggca gaccgttgcg atgtcctcac ttatgagttt gaaaatgtcg acgctgacgg
    17101 tttggatgcc gttatcaagg atggacaact ccctcaagga acagatctgc tccgcatttc
    17161 gcaaaatcgt atttttgaaa aggacttttt gtcaaacaag gctcaagtca ctgtggcacc
    17221 ctacaaggtc gtgacttcta gcctagactt ggcagatatc gacttgtcga aaaactatgt
    17281 cctcaagact gcgactggtg gctacgatgg tcatggacaa aaggttattc gttcagaagc
    17341 agacttggaa gcagcctatg cgctagcaga ctcagcagac tgcgtcttgg aagaatttgt
    17401 caactttgac cttgagattt ctgtcatcgt gtcaggaaat ggcaaggagg tgacgttttt
    17461 cccagttcag gaaaatatcc accgcaacaa tatcctgtct aagaccatcg taccagcccg
    17521 catttctgaa agtctagtag acaaggctaa agctatggca gtgcgaatcg cagaacaact
    17581 caacttgtct ggaactctct gtgtggaaat gtttgcgact gatgatgacg ttattgtcaa
    17641 tgaaatcgcc ccacgaccac ataactctgg gcactattct attgaagcct gtgatttctc
    17701 tcagtttgac acccatattc tcggtgttct cggagcacca ttaccagtca tcaaactcca
    17761 tgcgcctgcc gtcatgctta acgttctcgg ccagcatgtt gaggccgctg aaaaatatgt
    17821 cacagaaaat tcaagcgccc acctccacat gtatggtaaa atagaagcga agcacaaccg
    17881 caagatggga catgtgactt tgattagtaa tgaaccagat agtgtgggag agttttaggg
    17941 gagaggggtc taaagaaaaa atgtttgaaa aaattaaagg aattaatata aaatcaggta
    18001 tttttgaaga tgaaacaaaa ttagaactct ttgaaggaaa ttttgaggga acaaatccag
    18061 tacaaaacga tagggcaagt ttattgtttg gaaggaatgg ttcagggaaa agtaccattg
    18121 ctcgaggaat aaatcaatta aaaaatggtg agattggaac agatagagta tcatttattg
    18181 ataaaaataa taataatatt gtacttagtg atactgaacg aaaatcgata tttgttttca
    18241 atgaacacta tgttgatcag aaagtcaaaa ttgctcaaga agggttagat acaattgtaa
    18301 ttttaggtga acaggttgat atcgatgagg aactggatag attaagaacg cagttatcag
    18361 aatcacaaat tgaatctcaa gattattatg ctgaatatga agaatattta gatgaaaaaa
    18421 atgaaaaatc tccagatttt tggaaaaagg aaatgacaga ttctttgaaa ggagtaggca
    18481 actgggccga aagagatagg gagataaaag gaaatcgagc tgcatctccc gttcataata
    18541 atacctttca aaattttgtt gatttacaac caatcttaga taaaaatgag ttagaggttg
    18601 aattcaacaa taaaaaagct agatattttt caataagaga ttccgcagtt actataaata
    18661 atgaactatc tttacctgat attaattttg atagcaatga attatcaact ttattgtctg
    18721 aaaaaatcga agaacctgag ttgaattcta gggataagta tttactgaca ttattatctg
    18781 attccacaaa aggtgaacgt catttgagag aagttaaaga tttctttgaa gatgaacatc
    18841 aaaaaaaatg tcctttctgt actcaatcag tatcagaaga tgttaaagtt gaactcacga
    18901 atggcataac taaactacta tcaagagcag tcgaagaaca ccaatccgca ttgagaggta
    18961 aaaaaattga tgagattaat caagattttt ctggttatga acagatagat ccaatattaa
    19021 ttcagtctta tcaaaatagt attaatgctt tgaatgctaa atttaacgaa attaactcaa
    19081 taatcgataa gaagattgat aatccatata atatagttga gttacctaat ataagctttt
    19141 ctcaagaatt aagtcaagca gagcatgata ttgaaaaaat taaccaagca attatcaaac
    19201 ataattcaga aatctcgggt attcaaaagt taaaagtaga tctccttcaa ataaataatg
    19261 aattagcttt ttatgaaatt caagatgcat acaaaaagtt tcaagagaaa acaaataaaa
    19321 aagcaatttg tgaaaataat tataataaca gtagtaaacg agtaaaggat tatgagaagc
    19381 agatttctga tttagaagac aagaaactta atatagatat tgcagttgat gaaattaata
    19441 aaagtttaaa ttacatattt ttttcaaaaa atcggttagc tatacagaat caaaacggaa
    19501 aatactatct gttatcaaga ggtaagtctg tggtccccag tagggtttcc gtaggggaac
    19561 gaaatgcgct ggcattatgt tatttcttta ctgagataat tcaacagaga gagttagcag
    19621 atgcttatag tcatgaatat tttattgtta ttgacgatcc aatttctagt tttgatatgg
    19681 aaaataaagt tggaataacc tcgtatttaa aatattgttt aactagattt tttaagggga
    19741 atagtaatac tagagtttta ctaatgaccc atgataaaca aacaatatat gactttgata
    19801 tctttttgaa agagataatg gaatcctgta aagaagagga aggtggacaa aaatctaaat
    19861 acaagaagtt agaattggtt tctggtaaat tacaagaatt caaaactagt actcacgatt
    19921 atacagaact acttgaaata gtcttcggtt atgcattggg aaatagtaca cctacttcgg
    19981 aaagttttgt tgggaatgca atgagaaaaa ttttagaagc ctatggtagt tttaattata
    20041 agaagggaat tgccgagcta acaacagatc ctttaattgt tgaaaaaatt gataaagaat
    20101 acagaactta ttttgagaat cttatgtata gactggtttt aaacggtgaa agtcatttta
    20161 aggatccggt taaaactttg agtattgatt tctttgatac catttctgat gaagaacgaa
    20221 aaaaaacagc tagagattta ctagttttgc tttatctttt agatgattta catgttttaa
    20281 aacatttaga gggtgtatca aatgcggaaa atagacttga acaatggaag tgtgagattt
    20341 tagaataaga gaatcatacc atttgactta ttgcaatggt tgaagtttgc atgatagctg
    20401 attagagtaa tcaaaggatt attacttcct aattttattt tctacaaacc ctaatttagc
    20461 atctaataat gcaaagtttc ctgagcctca tagataaaaa agatttttaa ggagaaaaac
    20521 atgatcaacc gttactctcg ccctgagatg gcgaatattt ggagtgaaga aaataaatac
    20581 cgtgcttggc ttgaggtgga aatcctctct gacgaggcat gggctgagtt gggggaaatc
    20641 cctaaggaag atgtggcttt gattcgcaag aaggcggact ttgacatcga ccgtattttg
    20701 gaaattgagc aggagacgcg ccacgatgtg gtggctttca cgcgtgcggt ttctgagact
    20761 cttggtgaag agcgcaagtg ggttcactat gggttaactt ctaccgacgt ggtggatact
    20821 gcctatggtt acctctacaa gcaggccaac gacatcatcc gtcgtgacct tgaaaacttc
    20881 actaatatca tcgctgacaa ggccaaggag cacaagttca ccatcatgat ggggcgtact
    20941 catggtgtgc acgctgagcc gacaactttt ggtcttaaat tggcaacttg gtatagcgaa
    21001 atgaaacgca atatcgagcg cttcgagcat gcggctgctg gtgtagaagc tggtaagatt
    21061 tctggtgcgg ttgggaactt tgccaatatc ccaccatttg tagaggagta tgtctgcgat
    21121 aaacttggca tccgtgccca agaaatctct acacaagtcc ttcctcgtga ccttcacgct
    21181 gagtactttg cggttcttgc cagcattgcg acttcaatcg aacgtatggc gactgagatt
    21241 cgtggtctac aaaaatctga gcaacgcgaa gtagaagagt tctttgctaa agggcaaaaa
    21301 gggtcttcag caatgcctca caaacgcaac ccaatcggtt ctgaaaatat gactggtctg
    21361 gcgcgtgtca ttcgtggtca catgattacg gcttatgaaa acgtcgctct ctggcacgaa
    21421 cgcgatattt ctcactcatc agctgagcgt atcatcacac cagatacgac cattttgatt
    21481 gactacatgc tcaaccgttt tggaaatatc gtcaagaact tgacagtctt cccagaaaat
    21541 atgatccgaa acatgaactc gacttttggt cttatcttta gccaacgggc tatgttgaca
    21601 ttgattgaaa aaggcatgac ccgtgagcaa gcctatgact tggtgcaacc aaaaacagcc
    21661 tactcttggg acaaccaagt agactttaaa ccacttcttg aggcagattc agaagtaaca
    21721 tcacgtctca cacaagaaga aatcaatgaa atcttcaacc caatttatta caccaaacga
    21781 gtggatgata tctttgaacg tcttggacta ggtgattaat taaaaaataa acagcgagct
    21841 tcaatctcgc tgtttatttt ttatcgaaaa gacttagtct tcttttcttt tagtgagtcc
    21901 ataggctgct agtgtggaca tgagtcctgc gactactagt cctgcagaat cgtgagttcc
    21961 tgtttcagga agttttttct ctgttaccac aggagctgga tcttgaggaa gagctttgct
    22021 ttcctcagca ggagcagttg atggagctgg ttggcttggg atttctagtc ttggtttttc
    22081 ttcagcaata gcggcttgtc cgttttcatc gcctacatgt gttaccatag ttccgacttc
    22141 gactatttga gtaacggctt cctgtgctac gacactattt acaagtgttt tcacttcctt
    22201 accatcggca gaagtgctca cagagtagaa gttgctacga tgtccattga cgcccttagt
    22261 aatgacttgt gtttttcctt tgagtaagag tggattttca cgagtcactg tggtaaatgg
    22321 aatttcttct ttttggatat ccagtctagg ttttacctca gtagttggtg caagaccact
    22381 ttcatcaccc ttgtgagtta caggagcgcc aacttcaacc acttggttta taacttcttt
    22441 ggttacctgg ctatcaagga ctgtttctgt tgtttttcca ttttcagtga gtacagagat
    22501 gtaatgagtt cgttcacctt tgactcctgc tgtgataata ttttcctgac cagctgggag
    22561 gttaggattt tctttcttga taacttcaaa tggaatttct tcagttcttg tgatgagttc
    22621 tggtctggtt tcaacattgg cagccacttc attttcatcc aggcttcctg aatgagttgc
    22681 agctggtttg aggccttgaa gagcggcttt taggttggct acaagtgtgt caagctcagc
    22741 ttgtttatta cggttgaggt tgtaatttag agctgtttta gctgcgtcaa gggcctcaag
    22801 actttcttta ctatatcctt ctaagtttgt aggaatttta gctaattctt cgcggagagc
    22861 attataatta gcacggaagt agtctttgtt gtggtctgca aaggcagtca tgagttcaaa
    22921 gatttcctct tccttgtact cagcgcttgg tctatctgcc cagattgaaa gcatacttcc
    22981 gactgttgga agatctactt caggatattt ggtagaagct agttgattga atggaacttt
    23041 accagaattt tcaactgctt ttgaaagagg gtaagcttca tcttgtttgt gattgcctat
    23101 aacataatac cagtcaccgt tggtattcaa gaatttatag cctttgcttg ctaggtattg
    23161 aggtgatgcg aggttatatc cccaccagcc tttagaccag taagaaatca agacatcttt
    23221 gtcaaactga acatcgtcct tgtcttcata gtagaagcca tcgttgaagg ccattggttg
    23281 aagccctctt tctttggcca tagctgcgag ggtgttggca tattcggcaa atttgccata
    23341 gagttgatac cacttgaggt agtaccagcc ttgggcacta gtcgcatcgt tggcgtattc
    23401 gtcagtacca aagttgaaaa tctttgtttt acctgcaaag aagtccatgt atttaccgat
    23461 gagggctttt acaaagttca tcgcttcttc gtttttcaag tccatagttg tttttgaaac
    23521 tttatcaaag tgggcttgag gatttttaat acctaatttt tccatggcaa ccagcatagc
    23581 atccatgtga cctggactgt taatagctgg gatgagacca atgtccttag atttagcgta
    23641 ttcaattagc tctgtcactt ctgcctgtgt tagtgcagta ccgtttggat cgtcgtagta
    23701 agctttagtt ccttcgataa tagctttttt aacgtcatca ctagcatagg tttttccgtt
    23761 ggcagtaatg gtcatatcat tgagtagaaa gcgaagtccg tcatttccta gaaggagatg
    23821 gacatcagaa tatccgagct cactggcctt gtctacgatg cgtttgagct ggtccagagt
    23881 aaagtatttg cgtccagcat cgattgagat taccttgttt ttggcaagtt tttcaacctc
    23941 acgtttagct tcttcttctt tttgagcttc aggcgtgagg gtcaagttgt tgacagtttc
    24001 ttgaagttta gcaatggctt gatcaatcgt atcttgttgg gcacggctaa ggttgctatc
    24061 gagagagcga atagcttttt cagcttcttt tacggccgcg acgctttctg cagtataacg
    24121 gttcaggtct tttggtacct cgttaagtgc ttgctctgca gattcataat cagctgcgaa
    24181 gtattcagcg ttggcatttg caaaatgacg catgagtttg aagaggtgtg atggtgaata
    24241 acgtgcagat ggagtgtcag cccaagcagc taccatacca ccgatgattg ggatatcagc
    24301 tccttctgtt tttggtacag aagtgattgg tgtgttttta ataccattga gcccctgatc
    24361 gagattgtac cagccttggc catcagcgtt tcgtccaaga acgtagtacc aagcatcatt
    24421 ggtattaagg atttggtgac ctttttcagc tagtagttta gaagaagcga catcgtagcc
    24481 tccccaacca ccagtccaca tagaaacgat gatgtctttg tcaaaactac caaagcttgt
    24541 gtcgctattg tagtagatac cgtcgttaaa ggccattggt ttgagaccgt gcgattttac
    24601 aatacgagcg aggtcattgg cgtaggcaat aaatttttca tagcctttta cagggtagcc
    24661 ttcgtttgga tagtatttat cagcttgaag cacactccaa cctttagcat ctgtcgcatc
    24721 attggcatat tcatcaagtc cgatgttgaa gatttcagtc tttttcgcga aataagcagc
    24781 atacttgtcg ataagggctt ttgtaaaagc gacagcttgt tcgttgtcaa gatcgacagt
    24841 acgggctgat ttcttcccaa aatagctaaa gttagggttt tggattccca attctttcat
    24901 ggcattgaga atcgcatcca tgtgtccagg actatttact gtcggaatga gaccgatacc
    24961 tttatctttg gcatagttaa tcagatctgt catttgactt tctgttaagt gattgccgtt
    25021 tggatcgttg taataatcat ttgtaccttt ttcaatggcg cgtttgacat cgtcactggc
    25081 ataggtcttg ccgttagctg tgatgctcat atcgtccaac atgaaacgga gtccatcatt
    25141 tccgactaat aggtgtaaat cagtgtagcc ataatgtttc gctttatcga tgatttcctt
    25201 gagctgttct ggtgagaaat atttacgtcc agcatcaata gaaacaattt tctttttcgc
    25261 tagtttttca tttacagttg cagcacgttc ctttcctgtc tctgtttccg gtttgtcagc
    25321 ctctgctttc gcttcatctt ttttagctgg tttatccttg tcagtcttgt ctgtatttga
    25381 ctctttagaa tcaacctctt tcgcttcttc ctttttaggg ctagcttctt cttccttttt
    25441 attagcagtt tctttttcag cagaagttgg agttaccacc tctgctttat cactaggagt
    25501 tgaactaact tcctcttgtg gtttttcttc tgtttttgga agactagcta ccttatcagt
    25561 agctggagtt tctgtttcta cagtttttgg agcttctggt tgaagctctg ctttaggtgt
    25621 ttcctcagtc cgattttcgg atgattgagg ggaatcagaa accgtatgga tggtcggttg
    25681 gttttctgta gtagtaggag taactccatc ggctgcaaca gtctgtgctt ggaaggcaaa
    25741 tccaattaga acagaagctg ctcctacagc gtatttacga atagaaaaac gctgttgttt
    25801 ttcatgtttc attgcaaaac ctcctgattg cattgttata ttgatagcga ttatataaat
    25861 caacgccttt attttatttc ttatattaac gagagtcaag aggagatgac aaaaaactat
    25921 aataagtata aaaaaatata aaatttaaac ttaagatttc agattggtcg aaaaaataca
    25981 tatatatatc tagtataatt tttggttcta tttctataaa atattccaca aattatagaa
    26041 tcttccaaaa ataggtaagc gctacctttt tggtgtggta taataagcat agaaaaagcc
    26101 cgagcgatta ggctcaggct ttcttcttag tgatcacggt cacatgagat gaatttaatc
    26161 ttgtagtaat cagatcgttt gtaagtttca ctgtattcta aaacttggcc agttgattcg
    26221 agtttggtga ttttagtttg taggacagta gggaattgtt catcgactcc gaggactgaa
    26281 gccgcatgtt ctggagttgg aaagactatt tcgttgattt cttcaaagtg ttcatcattc
    26341 atgtgaatgt ggtagtctaa cttgaaacga ttatagatag aactatagta ttcaagattt
    26401 ggataatttg cgttgatata ttgttctggg atgtaggatg tatggtagat ataaacgaca
    26461 ccgtttgatt cgcggatacg ttcaatcttg tagtagaatt gatcgccgcg tagacccaat
    26521 ttttccaagt aaacaagctt gtttccgcgt tcaattgaaa gaacagttac cttatcatct
    26581 ttagcattga agagttcaat atctgaaaac tctacaagct tgtgtttgcg tgcacgtgaa
    26641 atgaaggttc cttttccttg ttggcggaca atatagccat ctttggcaag gtcgtttaag
    26701 gcgcgaacaa ctgtgataga gctgacatcg tacattgaaa tgagttctgc ttcagtgtaa
    26761 aatttatctc cactgctaaa ctgcccagag atgattttat tttttaattc gtcttttatg
    26821 tattgatatt tgggaattgc catattttta cctctatttt ccttctccat agaaaatttt
    26881 accataaaag cgaaaaaaat agtagtcttt tgaataaaaa attagaataa tagtttgaaa
    26941 aattaagcga tatagggatt gctcatattt tataaatgca ttctatacaa aattatttta
    27001 ggtactatat tccaaattta aagagcgttt gaaatgggtc taaaaatgtt tgaaactaat
    27061 tgaatgtgtg tataatagta aaaatgcagt aaatatcccg acaatttcta ttgacaattc
    27121 aaacagattg gtttataatt aatataacaa caaatgaaag cgcaaacttt cgcggtcgga
    27181 aggtagtttt atgacacgat ttgagatacg agatgatttc tatctcgatg gaaaatcatt
    27241 taagatttta tctggtgcca ttcattattt tagggttcct ccagaggatt ggtatcattc
    27301 gctctataac ttgaaggctc ttggttttaa tacggtagag acttatgttg cttggaattt
    27361 acacgagcct cgtgaaggtg agtttcattt tgaaggtgat ctggatttag agaaatttct
    27421 ccaaatagcg caggatttgg gtctctacgc aattgtgcgt ccgtctccat ttatctgtgc
    27481 ggaatgggaa ttcggtggct taccagcttg gctcttgacc aagaacatgc gaattcgctc
    27541 atccgaccca gcatatatcg aggcagttgg tcgctactat gatcagttat tgccaagact
    27601 ggtgcctcgt ttgttggaca atggtggcaa tattctcatg atgcaggttg aaaatgagta
    27661 tggttcttac ggagaagata aggcttacct gagagcgatt cgacagctaa tggaagagtg
    27721 tggcgtaacc tgtcctctct ttacatcaga tggtccatgg cgagctactc tgaaagctgg
    27781 aaccttaatt gaagaggacc tctttgtaac aggaaacttt ggttctaagg caccttacaa
    27841 cttttcgcag atgcaggaat tctttgatga acatggtaag aaatggccac tcatgtgtat
    27901 ggagttctgg gatggttggt tcaatcgctg gaaagaaccg attatcacac gggatcctaa
    27961 ggaattggca gatgcagttc gagaggtttt ggaacaagga tctatcaatc tttacatgtt
    28021 ccacggtggt acaaactttg gtttcatgaa tggttgctcg gctcgaggaa ctttggacct
    28081 gccacaagtt acgtcttatg attacgatgc ccttctggat gaagaaggaa atccaactgc
    28141 taaatatctt gcagtcaaga agatgatggc aacacatttt tcagagtatc cgcagttgga
    28201 accactctac aaagagagta tggagttgga tgctattcca ctagttgaaa aagtttcttt
    28261 gtttgaaacc ttagatagct tgtcaagtcc tgtagaaagt ctctatcctc aaaagatgga
    28321 ggagctggga caaagttatg gctacctact ttatcgaaca gaaacaaact gggatgcaga
    28381 agaagaaaga cttcgtatca ttgatggtcg agatagggcc cagctgtatg tcgatggtca
    28441 gtgggttaaa actcaatatc agacagagat tggggaagat attttttatc aaggtaaaaa
    28501 gaaagggcta tctaggttag atatcttgat agaaaatatg gggcgtgtca actatgggca
    28561 taagttctta gcggatacgc aacgtaaggg aattcggaca ggggtctgta aggatctgca
    28621 tttcttacta aactggaaac actatccact cccactagac aatcctgaga aaattgattt
    28681 ttcaaaagga tggactcaag gacaaccagc cttttacgct tatgacttta cagtcgaaga
    28741 gccaaaagat acttacctag acttgtctga gtttggtaag ggggttgcct ttgtcaatgg
    28801 gcagaatcta ggacgttttt ggaacgttgg cccaactctc tcactttata tccctcatag
    28861 ctatctcaag gaaggtgcca accgcatcat tatctttgaa acagaaggtc aatataaaga
    28921 agagattcat ttaactcgta aacctacact aaaacatata aagggggaaa acttatgaca
    28981 attgtaggat gccgtattga tggacgtttg atccacggac aagtagccaa tctttgggct
    29041 ggaaaactaa atgtttcacg cattatggtt gtagacgacg aagttgtcaa caacgatatt
    29101 gaaaagagtg gtttgaaact tgcgacacca ccaggtgtga aattgagtat tttgccagtt
    29161 gagaaagctg cagccaatat tcttgctggc aaatacgata gccaacgtct ctttatcgtg
    29221 gctcgtaaac cagaccgctt ccttggtttg gtagaagcag gtgtaccact tgaaaccctt
    29281 aatgttggga atatgtctca aacaccagaa actcgttcta ttacacgttc tatcaacgta
    29341 gtagacaagg atgtggaaga cttccacaaa ctggcagaaa aaggtgttaa acttactgct
    29401 cagatggttc caaatgatcc aatttcagac tttttgagct tattaaaata ggaaaaaaat
    29461 ttttaggagg tcattgttat gatacaatgg tggcaaattt tacttctcac tttgtactca
    29521 gcttatcaaa tctgtgatga gttgacgatc gtttcatctg caggttcccc tgtatttgct
    29581 ggtttcatta ctggtttaat catgggagat gtgactactg gtttacttat cggtggtaac
    29641 ttgcaactgt tcgttcttgg ggttggtacc ttcggtggtg cttctcgtat cgacgcaact
    29701 tctggtgcgg ttcttgcgac agccttctct gtttcacaag gaattgatgc accgcttgcc
    29761 attactacaa tcgctgtacc agtagcagct ctcttgactt acttcgacgt tcttggtcgt
    29821 atgactacta ccttcttcgc tcaccgtgtg gatgctgcaa tcgaacgctt tgactataaa
    29881 ggtattgaac gcaactactt gcttggtgcg attccgtggg ctctatctcg tgcccttcca
    29941 gtcttctttg cccttgcttt tggtggtgcc tttgtacaat cagtagtaga cttcgttgaa
    30001 gcctacaaat gggttgcaga tggcttgaca cttgcaggac gtatgcttcc aggtcttgga
    30061 tttgcaatct tgcttcgtta ccttccagtt aaacgtaacc ttcactacct tgctatggga
    30121 tttggtttga cagctatgtt gactgttctt tactcatatg taacaggtct tggtggcgct
    30181 gttgctggta tcgtaggtac tcttcctgct gaagttgctg aaaaaattgg tttcgtgaac
    30241 aacttcaaag gtttgtctat gattggtatt tctatcgtag gtattttcct tgcagtgctt
    30301 cacttcaaaa atagccaaaa agtagctgta gcagcacctt ctacaccatc agaaagtggg
    30361 gaaatcgaag atgacgaatt ctaattacaa acttacaaaa gaagatttta atcaaatcaa
    30421 caaacgtagc ttgtttactt tccaattagg ttggaactac gaacgtatgc aagcttctgg
    30481 ttacctttac atgatcttgc ctcagttgcg taaaatgtat ggtgatggaa ctcctgaatt
    30541 gaaagaaatg atgaaagttc atactcaatt cttcaatact tcaccattct tccataccat
    30601 tatcgctggt tttgaccttg ccatggaaga aaaagatggt gtaggttcaa aagacgccgt
    30661 taacggtatc aagacaggtt tgatgggacc attcgctcct cttggggata caatctttgg
    30721 ttcacttgta cctgctatca tggggtcagt cgcagcaact atggctatcg ctggccaacc
    30781 ttgggggatc ttcctttgga ttgcagttgc agtagcgtat gacatcttcc gttggaaaca
    30841 gttggaattt gcttacaaag aaggggttaa ccttatcaac aacatgcaaa gtaccttgac
    30901 agctttgatt gacgctgcat ctgtacttgg tgtcttcatg atgggtgctc ttgtagcaac
    30961 agtgattaac tttgaaattt cttacaagtt gccaatcggt gaaaagatga ttgatttcca
    31021 agacatcttg aaccaaatct tcccacgttt gcttccagca atctttactg cctttatctt
    31081 ctggttgctt ggtaagaaag gtatgaactc tactaaagct atcggtatta ttatcgtact
    31141 tgctttggct ctttctgccc ttggtcactt tgcacttgga atgtaattcc ttatgactaa
    31201 atcattaatt ttggtgagcc atggtcgctt ctgtgaggag cttagaggta gcacagaaat
    31261 gattatgggc ccacaagaca acatttacac agtagctctt cttccagaag atggcccaga
    31321 agaatttact gctaaatttg aagctgttat tgaaggattg gatgatttcc tagtctttgc
    31381 ggatcttctc ggtgggacac cttgtaatgt ggtgagtcgc ttgatcatgg aaggtcgtga
    31441 tattgacctt tacgcaggga tgaatcttcc aatggtgatt gaatttatca atgcgagcct
    31501 tacaggcgca gatgcggact acaagagccg tgctgcagaa agcattgtga aagttaatga
    31561 cctgttagcg ggcttcgatg atgacgaaga tgaataatac tcttcgaaaa tctcttcaaa
    31621 ctacgtcaac gtcgccttgc cgtaggtata tgttactgac ttcgtcagtc ttatccggca
    31681 acctcaaagc agtgctttga gcagcctgcg gctagtttcc tacagatttt agttggaact
    31741 cgattcaatt catgtgacaa cgtgaaaatc gttagagcat tttatataga atatacatgg
    31801 gaatgtagct tactcccatt cccatattta atagaaaaag aggaactcaa tgctacatta
    31861 tacaaaagaa gacttgctcg aattgggtgc agaaatcact acgcgtgaaa tctaccaaca
    31921 gcctgatgta tggagagaag cttttgaatt ttatcaagca aaacgtgaag aaattgcagc
    31981 cttcctacaa gaaatcgctg ataaacatga ctatattaag gttatcttga caggtgctgg
    32041 gacttctgct tatgtgggag ataccttgct accttatttt aaggaagtct atgacgaacg
    32101 caaatggaat ttcaatgcta ttgcgacaac agatatcgtt gccaatccag caacctattt
    32161 gaaaaaagat gtggcaactg tccttgtgtc ttttgctcgt agtgggaatt cgcctgaaag
    32221 tttggcgact gttgatttgg ccaaatcctt ggtggatgag ctttatcaag tgacgattac
    32281 ttgtgcagca gatggtaaat tggctcttca agctcacggt gatgatcgta atctcttgct
    32341 cttgcaacca gctgtctcta atgatgctgg atttgccatg acttctagct ttacgtctat
    32401 gatgttgaca actctcttgg tctttgatcc tacagaattt gctgttaagt ctgaacgttt
    32461 tgaagttgta tctagtcttg cccgtaaagt tttagacaag gcagaagatg tcaaagagct
    32521 cgttgattta gactttaacc gtgtcatcta tctaggcgct ggtcctttct ttggacttgc
    32581 tcatgaagct cagctcaaga ttttggaatt aactgctggt caagttgcga ccatgtatga
    32641 aagcccagtt ggcttccgtc acggtccaaa atctcttatc aacgacaata cagttgtttt
    32701 ggtctttggt acaacgacag actacactcg taagtacgac ttggacttgg ttcgtgaagt
    32761 tgctggtgac cagattgctc gtcgtgttgt gcttttgagt gatcaagctt ttggtcttga
    32821 aaatgtcaaa gaagtggccc ttggttgtgg cggtgtcttg aatgatattt accgtgtctt
    32881 cccttacatc gtttatgccc aactctttgc tttattgact tcactcaagg tagaaaataa
    32941 accagataca ccgtctccta caggtacagt aaaccgtgta gtacaaggtg tcataattca
    33001 cgaatatcaa aagtaagaca gtgtttatga attcttgaca agaggatttg taaattatca
    33061 gataaaccat agattgtcag tacgctttct atggtttgtt tgcttgagag aaatagtaaa
    33121 aggagaacag aatgaaagca tacacagagc gtgtatttgg aaatgttgag ggtgaggatg
    33181 tcttggccta tcgatttgag acagacggtg gctaccaact tgaggttatg acttatggtg
    33241 cgactatctt gcgctatgtc gcacctgaca aggctggaaa ttttgccaat gttatcttgg
    33301 gatttgatga ctttgatagt tatgtaggca atagtcccaa gcatggagca agtgtaggtc
    33361 ctgtagcggg tcgtattgca ggtgcgacct ttgagctcaa tggtaagacc tatgaccttg
    33421 aggttaataa tgctagcaac tgtaatcaca gtggttcaac tggttgggat tccagcttgt
    33481 ttgaagttga agaagtaagc gatcatggct tgactctcta cacagagcgt acagatggga
    33541 caggagggtt ccctggaaat ctcaagattt ggatcagtta tcacttggaa gaaactggtg
    33601 cctatgaaat cagctacaag gtaacgaccg atcaggatac gctggtcaat ccaaccaacc
    33661 acagctattt caacttgtct ggtgatttca cgcagacgat tgaccgtcat gtcttccaac
    33721 taaacacaga gggcatttac tcaatcgctc ctgacggtgt tcctgccaaa actccagaag
    33781 ccaaccgtga tgtggtcaaa cacgtctaca atggtacctt gttgaaggat atctttgcag
    33841 aagaagatga gcaaatccag ctggcatcag gtttggatca tccatttgcc cttcctgcag
    33901 gccatgacaa tgctggattc ctttatgacc aaaattcagg tcgcttcctg cttttcaaga
    33961 cagaagctcc ttgctttgtg gtctacacag caaactttgt ggatgaaagt gtcatcatag
    34021 gaggtcagcc aatgctacag cacaatggga ttgctcttga agcgcaagct ttaccagatg
    34081 ccattcacag tgaccttaaa ggccaagtca ttcttaaagc tggtcaaacc ttcaccagta
    34141 agacacgtta tgaacttgtt gtgaaataaa aaaagctggt caaaaagtct ttaaaattaa
    34201 aataacgcat attgtcaggt gatgaaaagt ttgataatat gcgttttatt atgaaatgat
    34261 ttactttata ttatcctgaa atggtgttat ttttgagtta tctggcttga ctttcttgat
    34321 ggaaattata taatagttgt aacaataata attacaacta gaaaagagga ccatttatga
    34381 cctatgaata caagagtcac atttatttgg cagagacagc tttaaatgta aaggatttgg
    34441 ccagtcaaac agccttttat cagcaagtta ttggtttaga aatcttatct caaactgaga
    34501 cagagtccat tctaggcctt ggtggaaaag tcttggtaca gctgattcaa gcacaagaga
    34561 gcggagaagt gagggaatat tatggtcttt accatttggc cattctcttg cccacacgca
    34621 aggctttagc tgatgtcttg aaacacctga cagatttaca aattcctctt gtcggcggtg
    34681 cagaccatgg ttacagtgaa gctatttact tggaagattt ggagggaaat ggcattgaac
    34741 tctatcgaga taagccagtt tccacatggg atattcgaga agatggacgc attatcggag
    34801 tgacggaggc tcttgcggcg caggacattt atgagttggg ggaaagagta gagcccttta
    34861 tcctggcaga aggtacaaga atggggcata ttcatctttc cgtcaaggat agtcgaaagt
    34921 ccagccagtt ttatcaaaag gtgttagggc tagagaataa attcagtgtg cctggcgcta
    34981 gttggattgc ggctggagat taccatcatc atttagcagt taacgaatgg ggaggaaaag
    35041 gtctggcttc gcgtaagcaa ggcttaccag gtttagccta ctatgtcatc gaagtcgcac
    35101 ataaaaaaga actgttaacg attgcccaac gagcacaaga agttgacgca ccaatcaaat
    35161 ggatgacatc gatccaattg gaaatcacag actcagatgg catcgtgacc cgtattcgtt
    35221 tagcaaggta aaattaggaa tttttaataa gttataagta ttgctagttt gctttttgaa
    35281 cggtctttgg taacagaact gcgtgagaat tttgacaaag aagctgatta gagatataat
    35341 gaagaaaaat cgagcaagga aaaagaactg acaaattcaa agtatattac ttgtttgaaa
    35401 cgttcagagg gccagttgtg tgggattcaa aagatgattg aaggagatcg tgactgtgct
    35461 gatattgtga cgcaactgac agcagtgaaa tctagtgtag agcgcgtgat tgagatgata
    35521 attaccgaaa atcttactga atgtatcaat cagcccctag atgattctga agctcaaaag
    35581 gaacgcctag aaaaggctat ccgatacttg attaaacgga aataaatgaa tgttttgaga
    35641 cgatatgtgc aaaggtctat taactattag aatagtttaa tgtgagtcaa aagaagttgt
    35701 aaaaaatctc taaaattaaa aaaacgcata gtatcaggtg ttgaatgtac tgacccccaa
    35761 aagttagatt ttttctgtct aacttttggg gtgcagttca taagaacctt ggtactatgc
    35821 gttttattat gtagagactt atactcttcg aaaatctctt caaaccacgt cagcttcacc
    35881 ttgccgta
//
LOCUS       DAVHTH010000016        35013 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.016, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000016 DAVHTH010000000
VERSION     DAVHTH010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 35013)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35013)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35013
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.016"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            complement(371..1351)
                     /locus_tag="VVR63_000834"
     CDS             complement(371..1351)
                     /locus_tag="VVR63_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylxylan esterase"
                     /protein_id="HEU6128867.1"
                     /translation="MKNPALLEEIKTYRGRDEVPEDFDAFWDGEVKNVSTLPSYHLEE
                     RDFHIPQVKCYELTFEGSKEGKVYARIVLPKSEEKVPLIFHFHGYMGRGWDWADMLGF
                     TVAGYGVVSMDVRGQSGYSQDGLRSPLGNTVKGHIIRGAMEGRDHLFYKDVYLDIYQL
                     VEIVASLSQVDEKRLSSYGASQGGALALVAAALNPRIQKTVAIYPFLSDFRRVIEIGN
                     TSEAYDELFRYFKFHDPFHETEEEIMATLAYIDVKNLAHRIQGEVKMITGLDDDVCYP
                     ITQFAIYNRLTCDKTYRIMPEYAHEAMNVFVNDQVYNWLCGSEIPFKYLK"
     gene            complement(1668..3683)
                     /gene="recG"
                     /locus_tag="VVR63_000835"
     CDS             complement(1668..3683)
                     /gene="recG"
                     /locus_tag="VVR63_000835"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HEU6128868.1"
                     /translation="MNLHQPLHVLPGVGPKSAEKYAKLGIENLQDLLLYFPFRYEDFK
                     TKQVLELEDGEKAVLSGQVVTPASVQYYGFKRNRLRFSLKQGEVVFAVNFFNQPYLAD
                     KIELGATLAVFGKWDRAKASLTGMKVLAQVEDDLQPVYRLAQGISQASLVKVIKTAFD
                     QGLDLLIEENLPQSLLDKYKLMSRCQAVRAMHFPKDLAEYKQALRRIKFEELFYFQMQ
                     LQMLKSENRVQGSGLVLNWSQEKVTAVKVSLPFALTQAQEKSLQEILTDMKSDHHMNR
                     LLQGDVGSGKTVVAGLAMFAAVTAGYQAALMVPTEILAEQHFESLQNLFPNLKLALLI
                     GSLKAAEKREVLETIAKGEADLIIGTHALIQDGVEYARLALIIIDEQHRFGVGQRRIL
                     REKGDNPDVLMMTATPIPRTLAITAFGDMDVSIIDQMPAGRKPIVTRWIKHEQLPQVL
                     TWLEGEIQKGSQAYVISPLIEESEALDLKNAIALSEELTTHFAGKAEVALLHGRMKSD
                     EKDQIMQDFKERKTDILVSTTVIEVGVNVPNATVMIIMDADRFGLSQLHQLRGRVGRG
                     DKQSYAVLVANPKTDSGKDRMRIMTETTNGFVLAEEDLKMRGSGEIFGTRQSGLPEFQ
                     VADIIEDFPILEEARKVASYISSIEAWQEDPEWRMIALHLEKKEHLD"
     gene            complement(3702..4805)
                     /locus_tag="VVR63_000836"
     CDS             complement(3702..4805)
                     /locus_tag="VVR63_000836"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000648075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HEU6128869.1"
                     /translation="MKASPHRPTKALIHLGAIRQNIQQMGAHIPQGTLKLAVVKANAY
                     GHGAVAVAKAIQDDVDGFCVSNIDEAIELRQAGLSKPILILGVSEIEAVALAKEYDFT
                     LTVAGLEWIQALLDKEVDLTGLTVHLKIDSGMGRIGFREASEVEQAQDLLQQHGVCVE
                     GIFTHFATADEESDDYFNAQLERFKTILASMKEVPELVHASNSATTLWHVETIFNAVR
                     MGDAMYGLNPSGAVLDLPYDLIPALTLESALVHVKTVPAGACMGYGATYQADSEQVIA
                     TVPIGYADGWTRDMQNFSVLVDGQACPIVGRVSMDQITIRLPKLYPLGTKVTLIGSNG
                     DKEITATQVATYRVTINYEVVCLLSDRIPREYY"
     gene            complement(4795..5163)
                     /locus_tag="VVR63_000837"
     CDS             complement(4795..5163)
                     /locus_tag="VVR63_000837"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HEU6128870.1"
                     /translation="MRMIVGHGIDIEELASIESAVTRHEGFAKRVLTAQEMERFTSLK
                     GRRQIEYLAGRWSAKEAFSKAMGTGISKLGFQDLEVLNNERGAPYFSQAPFSGKIWLS
                     ISHTDQFVTASVILEENHES"
     gene            complement(5202..6233)
                     /locus_tag="VVR63_000838"
     CDS             complement(5202..6233)
                     /locus_tag="VVR63_000838"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEU6128871.1"
                     /translation="MAFIEKGQEIDMEVIKAETQLSAEALRLKESRDRELADIISGED
                     DRILLVIGPCSSDNEEAVLEYARRLSALQKKVADKIFMVMRVYTAKPRTNGDGYKGLV
                     HQPDTSKAPSLINGLQAVRQLHYRVITETGLTTADEMLYPSNLILVDDLVSYHAVGAR
                     SVEDQEHRFVASGIDAPVGMKNPTSGNLGVMFNAIYAAQNKQTFLYHGQEVETSGNPL
                     AHVILRGAVNEYGNYMPNYYYENLLQAIERYETMGLENPFILIDTNHDNSGKQYMEQI
                     RIVRQTLQNRDWNEKIKKTVRGFMIESYLADGRQNQPEIFGCSITDPCLGWENTEALV
                     EEIYVTLTK"
     gene            complement(6235..7266)
                     /locus_tag="VVR63_000839"
     CDS             complement(6235..7266)
                     /locus_tag="VVR63_000839"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000232189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEU6128872.1"
                     /translation="MVFTAKSSKINIEEVRALSKLEGQALERKSQRDQELEAIIRGED
                     QRILLVIGPCSSDNEEAVLEYAKRLAVLQEEVADRIFMVMRVYTAKPRTNGDGYKGLI
                     HQPNATEAPSLINGIKAVRHLHYRVITETGMTTADEMLYPENLPLVDDLISYMAVGAR
                     SVEDQQHRFVASGAGFSTGFKNPTSGNLNVMFNGIYAAQNKQSFLFLGKEVETTGNPL
                     SHAILRGALNEYGKNIPNYYYDNLIDTIAQYEKMGLENPFIIIDTNHDNSGKQYIEQI
                     RIVRQTLINRAWNEKIKQFVRGFMIESYLEDGRQNEPEVFGKSITDPCLGWDNTEALV
                     REIYKTLGE"
     gene            complement(7347..9860)
                     /gene="secA"
                     /locus_tag="VVR63_000840"
     CDS             complement(7347..9860)
                     /gene="secA"
                     /locus_tag="VVR63_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HEU6128873.1"
                     /translation="MANILKTIIENDKGEIRRLEKMADKVFKYEDQMAALTDDQLKAK
                     TVEFKERYQNGESLDSLLYEAFAVVREGAKRVLGLFPYKVQVMGGIVLHHGDVPEMRT
                     GEGKTLTATMPVYLNALSGKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLATKS
                     PMEKKEAYECDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEAR
                     TPLIVSGANAVETSQLYHMADHYVKSLNKDDYIIDVQSKTIGLSDSGIDRAESYFKLE
                     NLYDIENVALTHFIDNALRANYIMLLDIDYVVSEEQEILIVDQFTGRTMEGRRYSDGL
                     HQAIEAKEGVPIQDETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIP
                     IPTNRPVQRIDHSDLLYASIESKFKAVVEDVKARYQKGQPVLVGTVAVETSDYISKKL
                     VAAGVPHEVLNAKNHYREAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERLKGIFERLNMSE
                     EAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYAQRYDVITADRDL
                     APEIQSMIKRTIERVVDGHARAKQDEKLEAILNFAKYNLLPEDSITMEDLSGLSDKAI
                     KEELFQRSLKVYDSQVSKLRDEEAVKEFQKVLILRVVDNKWTDHIDALDQLRNAVGLR
                     GYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIHEQERPQAERHISTTATRN
                     IAAHQASMPEDLDLSQIGRNELCPCGSGKKFKNCHGKRQ"
     gene            complement(10006..10293)
                     /locus_tag="VVR63_000841"
     CDS             complement(10006..10293)
                     /locus_tag="VVR63_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000940707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6128874.1"
                     /translation="MAHLKSFITRYSKVYIGLVLLIWLSFFFIPWDRAILGVRIDIFI
                     IQKILLAFGILSILMALLSKKVSLFVFGLICCLSLWINLFITFAILPIFGN"
     gene            complement(10321..10953)
                     /locus_tag="VVR63_000842"
     CDS             complement(10321..10953)
                     /locus_tag="VVR63_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU6128875.1"
                     /translation="MRLEIINGQKIYGKRPILNQLNLVFQSGKIYGLKGDNGSGKTVL
                     LKVLAGYIKLDKGKVLQDGKVYGIKNHYIQDAGILIEKVEFLSHLSLRENLELLRYFS
                     SKVTEKRIAYWIQYYDLQEFEDVEYRHLSLGTKQKMALIQAFISSPSILFLDEPMNAL
                     DEKSVRLTKQVILSYLKKENGLVILTSHISEDISDLCTDVLVVENGHIQM"
     gene            complement(10957..11598)
                     /locus_tag="VVR63_000843"
     CDS             complement(10957..11598)
                     /locus_tag="VVR63_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6128876.1"
                     /translation="MFKNFNNILLKRKIVLLLRIVLMMILINHLLSTAVQKQDAVIFF
                     KRELISIFSYNDYSEANLEIPKLLLNLSLFMVGWLSVILLESDLADHYHHLIRYQSSS
                     FFDYTRKRLVVISKFFTQDLFVWFLGLLPLGIHFKTVALFFLLAQLMMLYLLLSYLIA
                     LISAGAGFSFFLYFLVFVGQEWMMDHIVTVYLLLLSLLVMLIVSRLEEKFKKG"
     gene            complement(11591..12382)
                     /locus_tag="VVR63_000844"
     CDS             complement(11591..12382)
                     /locus_tag="VVR63_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6128877.1"
                     /translation="MKIPLLTLARHKFVYVLLTLLFLALVYRDVLMTYFFFDIHAPDL
                     AKFDGQAIKNDLLKSALDFRILQFNLGFYQSFIIPIIIVLLGFQYIELKNKVLRLSIG
                     REVSYPGLKRKLTLQVASIPCLIYLVTVLTIAIITYFLGTFSPLGWNSLFSDGSGLQR
                     LLDGEIKSYLFFTCVLLIGIFINAIYFLQIVDYVGNVTRSAITYLMFLWLGSMLLYSA
                     LPYYMVPMTSLMQASYGDVSLMKLFTPYILYIVPYMVLEKYEDNV"
     gene            complement(12404..12796)
                     /locus_tag="VVR63_000845"
     CDS             complement(12404..12796)
                     /locus_tag="VVR63_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6128878.1"
                     /translation="MKIKKLLKMVIPVLMISAVGTTFVEANQIGAFSNFVITTSYKRT
                     GYLTKENEGAEYIMNLNPCRNLHPMTVKHRIVNSNGEARSGESLTTCGTRSTHGNWAT
                     VGYVYAADMARQNWWDLSAAISGSWSPN"
     gene            13123..13974
                     /locus_tag="VVR63_000846"
     CDS             13123..13974
                     /locus_tag="VVR63_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU6128879.1"
                     /translation="MRWDYGQIFKEIRKSKGLTQQDVCGQVIHRTTLTNIEHGKVIPS
                     FENMVFLLEQIDMSLAEFKYICNEYHPSKRRDIIVESQNPSTFQDTRKMVELTEKCQK
                     YLKTHHDVPIQNIYRHTKIVTELRTKGFKNNHVLKDLYEEIWDYLEPMDTWYISDLKL
                     LGTILFFFPSENLPLLIDRIMKTIEKYKYFRETKAFLSSFLANLSTVYFQHHLFKECE
                     TITLQLLVLAEELKIYDILGFSQVRLGILQHNSDLIDKGITLLRLTKEEALVKILEKE
                     INDFSNL"
     gene            complement(14206..14556)
                     /locus_tag="VVR63_000847"
     CDS             complement(14206..14556)
                     /locus_tag="VVR63_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6128880.1"
                     /translation="MEHLFKMIILLPCFYFFSWIDKDNRESKFFPIFYYFYWIYITLY
                     ALFSLAWTVFSVLFFNIVLRNLTDIKLWGIWLLLLLIAFASDWLAYVFFKKMIRLRRE
                     LGKSKGVHKGRCRN"
     gene            complement(14696..15031)
                     /locus_tag="VVR63_000848"
     CDS             complement(14696..15031)
                     /locus_tag="VVR63_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6128881.1"
                     /translation="MEHLFKFLLLAPYFYFDNWIEKANRNSKFFPIFYYFYWFYIPFY
                     SLFSLAWTVVSVLFFNTVLRNVTDIKLWGIWFLFILLAIGMNWLTYSCFKEMFRLRQE
                     LGKSKGGRH"
     gene            complement(15119..16429)
                     /gene="der"
                     /locus_tag="VVR63_000849"
     CDS             complement(15119..16429)
                     /gene="der"
                     /locus_tag="VVR63_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HEU6128882.1"
                     /translation="MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEY
                     VARKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIV
                     ENLPNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFT
                     DTDGQEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYLPYAPIIFVSALTKQ
                     RLHKLPEMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKP
                     PTFVIFVNEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK"
     gene            complement(16443..17156)
                     /locus_tag="VVR63_000850"
     CDS             complement(16443..17156)
                     /locus_tag="VVR63_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent oxidoreductase"
                     /protein_id="HEU6128883.1"
                     /translation="MTETIKLMKAHTSVRRFKEQEIPQVDLNEILTAAQMASSWKNFQ
                     SYSVIVVRSQEKKDALYELVPQEAIRQSAVFLLFVGDLNRAEKGARLHTDTFQPQGVE
                     GLLISSVDAALAGQNALLAAESLGYGGVIIGLVRYKSEEVAELFNLPDYTYSVFGMAL
                     GVPNQHHDMKPRLPLENVVFEEEYQEQSTEAIQAYDRVQADYAGARATTSWSQRLAEQ
                     FGQAEPSSTRKNLEQKKLL"
     gene            complement(17153..18049)
                     /gene="dnaI"
                     /locus_tag="VVR63_000851"
     CDS             complement(17153..18049)
                     /gene="dnaI"
                     /locus_tag="VVR63_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HEU6128884.1"
                     /translation="MESVGDVLKRQPSRFYYQDLVQKIMKDPDVAAFIQQESLTPEEL
                     NRSISKFNQYITERDKFLRGDTDYIAKGYKPILVKNHGYADVSYEETPELIAAEKEAA
                     IKNRLKLINLPASLKKASLAQVDLDDLGRLPVFEKLLAFVEQYPAIRKGLYLYGDFGV
                     GKSFMVAALAHDLSEKRGVSSTLLHYPSFVIDVKNAISDGNVKTLVDEIKLSEVLILD
                     DIGAEQSTAWVRDEILQVILQYRMQENLPTFFTSNFNFEDLEKHFAKVKHGNDETWEA
                     RRVMERIRYLAEETRLEGVNRR"
     gene            complement(18050..19219)
                     /locus_tag="VVR63_000852"
     CDS             complement(18050..19219)
                     /locus_tag="VVR63_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation and membrane attachment
                     family protein"
                     /protein_id="HEU6128885.1"
                     /translation="MKPIDRFSYLKNNRVSQDTSSLVQCYLPIIGQEALSLYLYTISF
                     WDNGRKEYLFSSILNHLNFGMDRLIKSLKILSAFNLLTLYQKGDVYQLALHAPLSSQD
                     FLEHPVYRRLLEKKIGDSAVEDLKVESADGEEIPVSLNQVFPELAELGSQEDLGLKKK
                     VANDFDLEHFRRLMARDGLRFADEQSDVLNLFAIAEEKKWTWFETYQLAKSTAVSQVI
                     STKRMREKIAQKPVSSDFSLKETTIIKEAKSKTALQFLAEIKQTRKGTITQTERELLQ
                     QMAGLGLLDEVINIILLLTFNKVDSANINEKYAMKVANDYAYQKIHSAEKAVLRIRER
                     GQKAKTQKQNQTAPVKTNVPKWSNPEYKNETSEETRLELERKKQELLARLEKGGD"
     gene            complement(19220..19693)
                     /gene="nrdR"
                     /locus_tag="VVR63_000853"
     CDS             complement(19220..19693)
                     /gene="nrdR"
                     /locus_tag="VVR63_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HEU6128886.1"
                     /translation="MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERV
                     EERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENE
                     IQSEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER"
     gene            19833..20198
                     /locus_tag="VVR63_000854"
     CDS             19833..20198
                     /locus_tag="VVR63_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEU6128887.1"
                     /translation="MSWTFDNKKPIYLQIMEKIKLQIVSHTLEPNQQLPTVRELASEA
                     GVNPNTIQRALSDLEREGFVYSKRTTGRFVTKDKELIAQSRKQLSEEELEHFVSSMTH
                     FGYEKEELPGVVSDYIKGV"
     gene            20203..20898
                     /locus_tag="VVR63_000855"
     CDS             20203..20898
                     /locus_tag="VVR63_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6128888.1"
                     /translation="MSLLVFENVSKSYGATPALENVSLDIPAGKIVGLLGPNGSGKTT
                     LIKLINGLLQPDQGRVLINDMDPSPATKAVVAYLPDTTYLNEQMKVKEALTYFKTFYK
                     DFNLERAHHLLADLGIDENSRLKKLSKGNKEKVQLILVMSRDARLYVLDEPIGGVDPA
                     ARAYILNTIINNYSPTSTVLISTHLISDIEPILDEIVFLKDGKVVRQGNVDDIRYESG
                     ESIDQLFRQEFKA"
     gene            20915..21682
                     /locus_tag="VVR63_000856"
     CDS             20915..21682
                     /locus_tag="VVR63_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000498762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6128889.1"
                     /translation="MFWNLVRYEFKNVNKWYLALYAAVLVLSALIGIQTQGFKNLPYQ
                     ESQATMLLFLATVFGGLMLTLGISTIFLIIKRFKGSVYDRQGYLTLTLPVSEHHIITA
                     KLIGAFIWSLISTAVLALSAVIILALTAPEWIPLSYVITFVETHLPQIFLTGISFLLN
                     TISGILCIYLAISIGQLFNEYRTALAVAVYIGIQIVIGFIELFFNLSSNFYVNSLVGL
                     NDHFYMGAGIAIVEELIFIAIFYLGTYYILRNKVNLL"
     gene            complement(22035..23234)
                     /locus_tag="VVR63_000857"
     CDS             complement(22035..23234)
                     /locus_tag="VVR63_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6128890.1"
                     /translation="MRNMWVVIKETYLRHVESWSFFFMVISPFLFLGISVGIGHLQGS
                     SMAKNNKVAVVTTVPSVAEGLKNVNGVNFDYKDEASAKEAIKEEKLKGYLTIDQEDSV
                     LKAVYHGETSLENGIKFEVTGTLNELQNQLNRSTASLSQEQEKRLAQTIQFTEKIDEA
                     KENKKFIQTIAAGALGFFLYMILITYAGVTAQEVASEKGTKIMEVVFSSIRASHYFYA
                     RMMALFLVILTHIGIYVVGGLAAVLLFKDLPFLAQSGILDHLGDAISLNTLLFILISL
                     FMYVVLAAFLGSMVSRPEDSGKALSPLMILIMGGFFGVTALGAAGDNLLLKIGSYIPF
                     ISTFFMPFRTINGYAEGAEAWISLAITVIFAVVATGFIGRMYASLVLQTDDLGIWKTF
                     KRALSYK"
     gene            complement(23231..24124)
                     /locus_tag="VVR63_000858"
     CDS             complement(23231..24124)
                     /locus_tag="VVR63_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6128891.1"
                     /translation="MLEVRSLEKSFGSKQVLFGIDFQARPGRILGLVGKNGAGKTTIF
                     HSILKFLEYQGEIGLDGQDIRQEIYARIGYLPEERSLMPKLTVLEQVRYLATLKGMDA
                     KEVKEKLPQWMKRLEVKGKLTDKIKSLSKGNQQKIQLIITLIHEPDLIILDEPFSGLD
                     PVNTELLKQVIFQEKERGATIIFSDHVMTNVEELCDDILMIRDGRVVLHGPVQDVRNQ
                     YGKTRLFVSSERSKEELENLPHVKQVSLTKQGSWKLILEDESAGRELFPILTQGQYIA
                     TFDQQAPTIDEIFKLESGVEV"
     gene            24241..24321
                     /locus_tag="VVR63_000859"
                     /pseudo
     CDS             24241..24321
                     /locus_tag="VVR63_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            24831..25019
                     /locus_tag="VVR63_000860"
                     /pseudo
     CDS             24831..25019
                     /locus_tag="VVR63_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            25434..26051
                     /locus_tag="VVR63_000861"
     CDS             25434..26051
                     /locus_tag="VVR63_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEU6128892.1"
                     /translation="MSQDKQMKAVSPLLQRVINISSIVGGVGSLIFCIWAYQAGILQS
                     KETLSAFIQQAGIWGPPLFIFLQILQTVVPIIPGALTSVAGVFIYGHIIGTIYNYIGI
                     VIGCAIIFYLVRLYGAAFVQSVVSKRTYDKYIGWLDKGNRFDRFFIFMMIWPISPADF
                     LCMLAALTKMSFKRYMTIIILTKPFTLVVYTYGLTYIIDFFWQML"
     gene            complement(26371..27258)
                     /locus_tag="VVR63_000862"
     CDS             complement(26371..27258)
                     /locus_tag="VVR63_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEU6128893.1"
                     /translation="MTKLYGSLEAGGTKFVCAVGDENFNVVEKTQFPTTTPIETIDKT
                     IEFFSKFDNLAGLAVGSFGPIDIDKNSKTYGFITTTPKPNWANVDLLGALRRALNVPM
                     YFTTDVNSSAYGEVVARNNAGGRIENLVYYTIGTGIGAGVIQRGEFIGGVGHPEMGHY
                     YVARHPMDIEKEFKGVCPFHKGCLEGYAAGPSLEARTGVRGETIELNNPVWDVQAYYI
                     AQAAVNATVTFRPDVIVFGGGVMAQQHMLDRVREKFTSLLNGYLPVPDVRDYIVTPAV
                     AGNGSATLGNFVLAKEVSK"
     gene            complement(27407..29290)
                     /locus_tag="VVR63_000863"
     CDS             complement(27407..29290)
                     /locus_tag="VVR63_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEU6128894.1"
                     /translation="MNNQEIAKKVIDALGGRENVNSVAHCATRLRVMVKDEEKINKEV
                     IENLEKVQGAFFNSGQYQIIFGTGTVNKMYDEVVVLGLPTSSKDDMKAEVAKQGNWFQ
                     RAIRTFGDVFVPIIPVIVATGLFMGVRGLFNALEMPLPGDFATYTQILTDTAFIILPG
                     LVVWSTFRVFGGNPAVGIVLGMMLVSGSLPNAWAVAQGGEVTAMNFFGFIPVVGLQGS
                     VLPAFIIGVVGAKFEKAVRKVVPDVIDLLVTPFVTLLVMSILGLFVIGPVFHVVENYI
                     LIATKAILSMPFGLGGFLIGGVHQLIVVSGVHHIFNLLEVQLLAADHANPFNAIITAA
                     MTAQGAATVAVGVKTKNPKLKTLAFPAALSAFLGITEPAIFGVNLRFRKPFFLSLIAG
                     AIGGGLASILGLAGTGNGITIIPGTMLYVGNGQLPQYLLMVAVSFALGFALTYMFGYE
                     DEVDATAAAKQAEVAEEKEEVAPAALQNETLVTPIVGDVVALADVNDPVFSSGAMGQG
                     IAVKPSQGVVYAPADAEVSIAFPTGHAFGLKTRNGAEVLIHVGIDTVSMNGDGFEAKV
                     AQGDKVKVGDVLGTFDSNKIATAGLDDTTMVIVTNTADYASVAPVATGSVAKGDAVIE
                     VKI"
     gene            29667..31121
                     /locus_tag="VVR63_000864"
     CDS             29667..31121
                     /locus_tag="VVR63_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEU6128895.1"
                     /translation="MEWTTERRYRLYQDWTQEEIQHIKENMAQSPWHTHYHVEPKTGL
                     LNDPNGFSYFDGKWILFYQNFPFGAAHGLKSWAQLESDDLVHFRETGVKVLPDTPLDS
                     HGAYSGSAMQFGDNLFLFYTGNVRDENWIRHPYQIGALMDKEGKITKIDKILIDQPAD
                     STDHFRDPQIFNFKGQYYAVVGGQDLEKKGFVRLYKAVNNDYTNWQAVGDLDFANDRT
                     AYMMECPNLVFVEEQPVLLYCPQGLDKKVLDYDNIFPNMYKIGASFDPKNAKMVDVSQ
                     LQNMDYGFEAYATQAFNAPDGRALAVSWLGLPDVSYPSDRFDHQGTFSLVKELTIKDD
                     KLYQYPVAAIKDLRTSEEAFSNRSQTKNTYELELNLEANSQSEIVLLADKEGKGLSIN
                     FDLVNGQVTVDRSQAGEQYAQEFGITRSCPIENQATTATIFIDNSVFEIFINKGEKVF
                     SGRVFPHADQNGILIKSGNPTGTYYELDYGRKTN"
     gene            31102..32067
                     /locus_tag="VVR63_000865"
     CDS             31102..32067
                     /locus_tag="VVR63_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU6128896.1"
                     /translation="MVAKLTDVAKLAGVSPTTVSRVINKKGYLSEKTIQKVNEAMREL
                     GYKPNNLARSLQGKPAKLIGLIFPNISNVFYAELIDKLEHQLFKNGYKTIICNSEHDS
                     EKEREYIEMLEANQVDGIISGSHNLGIEDYNRVTAPIISFDRNLSPDIPVVSSDNYAG
                     GVLAAQTLVKTGAQSIIMITGNDNSNSPTGLRHAGFASVLPKAPIINVSSDFSPVRKE
                     MEIKNILTREKPDAIFASDDLTAILVIKIAQELGISVPKELKVIGYDGTYFIENYYPQ
                     LATIKQPLEEIACLTIDLLLQKIEGKEVATTGYFLPVTLLPGKSI"
     gene            complement(32102..33376)
                     /locus_tag="VVR63_000866"
     CDS             complement(32102..33376)
                     /locus_tag="VVR63_000866"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HEU6128897.1"
                     /translation="MKISWNGFSKKSYQERLELLKAQALLSPERQASLEKDEQMSVTV
                     ADQLSENVVGTFSLPYSLVPEVLVNGQEYTVPYVTEEPSVVAAASYASKIIKRAGGFT
                     AQVHQRQMIGQVALYQVANPKLAQEKIASKKAELLELANQAYPSIVKRGGGARDLHVE
                     QIKGEPDFLVVYIHVDTQEAMGANMLNTMLEALKPVLEELSQGQSLMGILSNYATDSL
                     VTASCRIAFRYLSRQKDQGREIAEKIALASQFAQADPYRAATHNKGIFNGIDAILIAT
                     GNDWRAIEAGAHAFASRDGRYQGLSCWTLDLEREELVGEMTLPMPVATKGGSIGLNPR
                     VALSHDLLGNPSARELAQIIVSIGLAQNFAALKALVSTGIQQGHMKLQAKSLALLAGA
                     SESEVAPLVERLISDKTFNLETAQRYLENLRS"
     gene            complement(33376..34548)
                     /locus_tag="VVR63_000867"
     CDS             complement(33376..34548)
                     /locus_tag="VVR63_000867"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004181031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HEU6128898.1"
                     /translation="MTIGIDKIGFATSQYVLKLQDLAEARGIDPEKLSKGLLLKELSI
                     APLTEDIVTLAASASDSILTEQERQEVDMVIVATESGIDQSKAAAVFVHGLLGIQPFA
                     RSFEIKEACYGATAALHYAKLHVENSPESKVLVIASDIAKYGIETPGEPTQGAGSVAM
                     LITQNPRMMAFNNDNVAQTRDIMDFWRPNYSTTPYVNGVYSTQQYLDSLKTTWLEYQK
                     RYQLTLDDFAAVCFHLPYPKLALKGLKKIMDKNLPQEKKDLLQKHFDQSILYSQKVGN
                     IYTGSLFLGLLSLLENTDSLKAGDKIALYSYGSGAVAEFFSGELVEGYEAYLDKDRLN
                     KLNQRTALSVADYEKVFFEEVNLDETNSAQFAGYENQDFALVEILDHQRRYSKVEK"
     gene            complement(34679..34927)
                     /locus_tag="VVR63_000868"
     CDS             complement(34679..34927)
                     /locus_tag="VVR63_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6128899.1"
                     /translation="MVSSSGSEFQSGWQEHQLIAEKVSKTLDKTFDKDVREIPISQFY
                     QKFVDEMGRIYSGNLILQELITVNGAYKATYIGELSSN"
BASE COUNT        10351 a         7757 c         6526 g        10379 t
ORIGIN      
        1 cggcaaggcg aagctgacgt ggtttaaaga gatttttgaa aagtattaac acctacagac
       61 aagcctgacg atagcaagaa ctaccctact cgataggtat cggcttttgc tttctgaaaa
      121 aaattatttt aagcaatttg acaaatctag caacaaaaaa ttctataaat ataatagatt
      181 gaaactagaa tagtacacat ttgcttctaa aacattgtta gaaatcgatt tgactgtcct
      241 gatcgttttg tcctattctt gtttcatttt actatatttc catgataaaa cgcatagtat
      301 caagtttttt taatcccctg atactatgcg tgtttgtaat ttttaagatt ttgtgcttag
      361 agtcgactcc ttattttaga tatttaaaag gaatctcact tccacagagc cagttgtaga
      421 cttggtcatt gacaaataca ttcatggctt cgtgagcata ctcaggcatg atgcgatagg
      481 ttttatcgca ggtcagacga ttataaatcg caaactgggt aatgggatag caaacatcgt
      541 cgtccaagcc cgtaatcatc ttaacctcac cttggatacg atgggcaaga tttttgacat
      601 cgatataggc aagggtcgcc atgatttcct cctctgtttc atggaagggg tcgtgaaact
      661 tgaaataacg gaaaagttcg tcgtaagcct cgctagtatt accaatctca atcacccgtc
      721 tgaagtctga caagaaggga taaatggcaa ctgttttctg aattcgagga ttgagcgctg
      781 ctgcaactag agctagagcc cctccttgtg aggcaccata gctagaaaga cgcttctcat
      841 caacctgaga cagactagca acaatttcga ccaactggta aatatccaga taaacatcct
      901 tataaaagag gtggtcccga ccttccatag caccacggat aatatgcccc ttcacggtat
      961 ttcctaaagg agaacgcaag ccgtcttgtg agtaacctga ctggccccgc acatccatgg
     1021 aaacaacacc gtaaccagct acggtgaagc ccagcatgtc ggcccagtcc cagccacgtc
     1081 ccatataacc atgaaaatgg aagattaatg gaaccttctc ctcactcttt ggaagaacaa
     1141 tgcgtgcata gacctttcct tccttgcttc cttcaaatgt taactcatag cacttgactt
     1201 gaggaatgtg gaaatctctt tcctccaagt ggtaggatgg aagtgtggaa acatttttca
     1261 cttccccatc ccagaaagca tcaaagtctt ccggaacctc atcccttcct ctataggtct
     1321 taatttcttc tagcaaagct ggatttttca tagcatgctc cttttatttt gtaatcgtta
     1381 ccacaactgt agcatatcta tgtaatcaat gcaagaaaga agggtaaata gaaagtgaat
     1441 ttagattctt tacttttagg atgatgggct gaaagtagtt ttagaaacga aaaaagagca
     1501 tttcgctctc tcttctgttt atactagttt tttgcttcct tcttttggaa agtggtttgg
     1561 taatttactt taatcgttac tgtcatatga gagtcctcgt ttctttttga tgactttagt
     1621 ataagagcca aacctaaaaa ctagcttaag ttttccttag agaaagctta atccagatgt
     1681 tctttctttt ccagatgaag ggcaatcatg cgccactctg gatcttcttg ccaagcttct
     1741 atagaactaa tgtagctagc aacctttctt gcttcttcta aaatcggaaa atcttcgata
     1801 atatcagcca cttggaactc tggaagtcct gactgtctgg ttccaaaaat ctcaccagaa
     1861 ccacgcattt tcaaatcttc ctccgcaagg acaaatccat tggtcgtttc tgtcatgata
     1921 cgcatgcggt ctttcccaga atccgtcttg ggattagcaa cgagaacagc gtaggactgc
     1981 ttgtcccccc gaccgacacg acctctaagc tggtgaagtt gactgagacc gaagcgatcg
     2041 gcatccatga taatcatgac agtcgcattg ggaacgttga ccccaacctc aataaccgtc
     2101 gtcgaaacca gaatatccgt ctttctctcc ttgaaatcct gcatgatctg gtctttttcg
     2161 tcactcttca tcctaccatg tagaagagcc acctctgcct tgcctgcaaa atgagtcgtc
     2221 aactcctctg ataaggcaat ggcatttttc aaatctagag cttctgattc ttcaatcaaa
     2281 ggagagatga cataggcttg ggaacctttt tgaatttccc cctctaacca agtcaagacc
     2341 tgaggtagtt gctcatgttt gatccagcgc gtcacaatag gcttccgacc tgctggcatc
     2401 tggtcgataa tggaaacatc catatctcca aaggctgtga tggcaagcgt ccgtggaatg
     2461 ggagtcgccg tcatcatgag gacatctgga ttgtcacctt tttcccgtaa aatacgcctt
     2521 tgccctacac caaaacggtg ctgctcatcg ataataatca aagcaagacg agcatactcc
     2581 accccatctt gtatcagagc gtgagttccg ataatcaaat cagcctcacc cttggcaatg
     2641 gtctccaaga cctctctctt ttctgcagct ttcaaggaac ctatcaagag agccagtttc
     2701 aaattgggaa aaaggttctg taaactctca aagtgttgct ctgcgaggat ttctgttggt
     2761 accattaggg cagcctgata acctgctgtc actgccgcaa acatggccaa gccagcgact
     2821 accgtttttc cactccccac atccccttgt aggagacgat tcatgtggtg gtcggacttc
     2881 atatcagtta aaatttcctg caaactcttt tcctgagctt gggtcagggc aaaaggaaga
     2941 cttactttaa ctgctgtcac tttttcctga gaccaattca gaaccagacc acttccctga
     3001 actctatttt cagacttgag catctgcagc tgcatttgga aataaaagag ttcctcaaac
     3061 tttatacggc gaagagcctg cttgtattct gccaaatcct ttggaaaatg catagctcgg
     3121 actgcctgac aacgggacat gagtttgtat ttgtctagta aagactgggg cagattttct
     3181 tctatcaaga ggtccagtcc ctgatcaaaa gccgtcttga tgaccttgac cagactggcc
     3241 tgactgattc cctgagccag acgatagaca ggctggaggt catcttctac ctgagccaga
     3301 accttcatcc cagtcagact agccttagcg cggtcccatt ttccaaagac agcaagggtt
     3361 gctcccaact ctattttatc agccagatag ggctggttaa agaaattcac cgcaaaaacg
     3421 acctctccct gcttgagact aaaacgcagg cgattgcgct tgaaaccata atactggaca
     3481 ctagcaggag tcactacctg accagaaaga actgccttct caccgtcttc cagctccagc
     3541 acctgcttgg ttttgaagtc ttcataacgg aaaggaaagt agagcaagag atcttgcaag
     3601 ttttcaattc ctagtttggc gtatttttct gctgactttg gtcccacacc aggcaagaca
     3661 tgcaagggtt gatgtagatt catgctccac tcctttcttt tctaataata ttctctcgga
     3721 atacggtcgc tgaggaggca aaccacctca tagttaatgg ttacgcggta ggtcgctacc
     3781 tgagttgcag tgatttcctt atccccattg gagccaatca aggttacctt ggttcctagc
     3841 ggataaagct taggcaatcg aatagtgatt tggtccatcg aaaccctgcc gacaattggg
     3901 caagcttggc catctaccaa gacagagaaa ttttgcatgt ctcttgtcca tccatctgca
     3961 tacccgattg gcacggtcgc gatgacttgc tcgctatccg cttgataagt tgctccatag
     4021 cccatgcaag ctccagctgg aactgtcttg acatgaacca gagcagactc caaggtcaag
     4081 gccggtatca aatcataagg caaatccaag accgctccac ttggattgag gccatacatg
     4141 gcatctccca tacgaaccgc attgaaaata gtctctacat gccaaagagt cgttgcagaa
     4201 ttgctagcat gaaccagctc tggaacttcc ttcatactag ctaaaatagt tttaaaccgt
     4261 tctaactggg cattaaaata gtcatctgat tcctcatcag cagtagcaaa gtgggtaaag
     4321 attccttcaa cacaaacacc gtgttgttgg agcaaatctt gagcctgctc aacctcactt
     4381 gcctctctaa aaccaatccg tcccatccct gaatcaatct tgaggtggac tgtcaatcca
     4441 gttaggtcca cttccttatc taagagtgct tgaatccact ccagtccagc cactgtcaag
     4501 gtgaagtcat attctttagc tagagcaaca gcttcgattt cagaaactcc taaaatgagg
     4561 attggcttgc tgagtccagc ttgtctgagt tcaatggctt catcgatatt ggaaacgcaa
     4621 aagccatcaa catcatcttg aattgccttg gcaacggcaa cagctccatg accataagca
     4681 ttggccttaa ccacagccaa cttgagcgtt ccttgaggga tatgagcccc catttgctga
     4741 atattttgtc gaatagctcc cagatgaatc agagccttgg ttggtctatg tggactagct
     4801 ttcatgattt tcctccaaaa tgacactggc tgtcacaaac tgatcggtgt ggctgataga
     4861 cagccaaatc tttcctgaaa atggtgcctg actaaaataa ggcgccccac gttcattgtt
     4921 caagacttcc aaatcctgaa aaccgagctt gctaatgccc gttcccatag ccttggaaaa
     4981 ggcctcctta gccgaccagc gaccagctaa atattctatt tgcctgcgtc ctttgagact
     5041 ggtgaagcgc tccatttcct gagcggtcag tacacgctta gcaaatcctt catgtcgtgt
     5101 aactgcgctt tctatcgaag ccaattcttc gatgtcaatt ccgtgtccaa ctatcattct
     5161 catcaaaagg agttgagatt ccccaactcc atccttttca cttattttgt caaggtaaca
     5221 taaatctctt ctaccaaggc ctctgtattt tcccaaccta ggcaagggtc agtaatagag
     5281 caaccaaaga tctctggttg gttttgacga ccatctgcta ggtaagattc aatcataaat
     5341 cctcgaaccg tctttttaat tttctcattc caatcacgat tctgcaaggt ctggcgaaca
     5401 attcgaatct gctccatata ttgcttgcct gagttatcat ggttggtgtc aatgaggata
     5461 aaaggatttt caagtcccat ggtttcatag cgttcaatgg cttggagtag attttcatag
     5521 tagtaattcg gcatataatt gccatactcg ttgactgctc cacggaggat aacatgggcc
     5581 aaaggattac ctgatgtctc aacttcctgc ccatgataaa ggaaggtttg cttgttttga
     5641 gcagcataga tggcgttaaa cataacaccc aaatttcctg aggttggatt tttcatccct
     5701 actggtgcat caatcccaga agccacaaag cggtgctctt ggtcttccac agaacgagct
     5761 ccaacggcat ggtagctgac caagtcatcc accaagatca gatttgacgg ataaagcatc
     5821 tcatctgccg ttgtcaaacc agtctctgta atcacgcggt agtgcaactg gcgcacagcc
     5881 tgcaagccat taatcaggct tggagcctta gaagtatctg gctggtgaac taatccttta
     5941 tagccgtctc cattggtacg aggcttagca gtatacacgc gcatgaccat gaaaatctta
     6001 tccgctacct tcttttgcaa ggcagataaa cggcgagcat attccaagac cgcctcttca
     6061 ttatcagaag agcaaggacc aatcaccaag agaatacggt catcttcccc tgaaataata
     6121 tctgccaatt ccctgtcacg gctttccttg agtctcaagg cttccgcaga caattgggtt
     6181 tcagccttga tgacttccat atcgatttct tgaccttttt caataaatgc catcttattc
     6241 tcctaacgtt ttgtaaattt ctctgacaag agcttctgtg ttatcccaac ccaggcaagg
     6301 gtctgtgata gacttaccaa atacttctgg ctcattttgt cgaccatctt ccagataaga
     6361 ctcaatcata aaaccacgaa cgaactgctt aattttttca ttccaagcac ggttaatcaa
     6421 ggtctggcgg acaattcgga tctgttcaat atactgctta ccagaattgt catgattggt
     6481 atcaatgatg ataaaaggat tttccaagcc cattttctca tactgggcaa tggtatcaat
     6541 taaattgtca taatagtagt tgggaatatt ttttccatac tcattaagag caccacgaag
     6601 aatagcgtgt gaaagcgggt tcccagttgt ttctacttct tttcctaaga aaaggaaact
     6661 ttgtttgttt tgagcagcat aaatcccatt aaacatgaca ttgagatttc cagaggttgg
     6721 atttttaaaa ccagtagaaa atcctgcccc acttgccaca aagcggtgtt gctggtcttc
     6781 aactgagcgg gcaccaactg ccatgtaaga aatcaaatca tctacaagcg gaaggttttc
     6841 aggataaagc atttcatcag cagttgtcat ccctgtttct gtgatgacac gatagtgaag
     6901 atggcgaacg gctttgattc cattgataag actaggcgct tctgtcgcgt taggctggtg
     6961 aatcaagccc ttatagccat ctccgttggt acggggtttg gcagtataaa cacgcataac
     7021 cataaagata cgatctgcca cttcttcttg taggactgcc aaacgcttag cgtattcaag
     7081 gacagcttct tcgttgtcag atgagcatgg cccgattacc aagagaattc gctggtcttc
     7141 tccacgtata atggcttcta gctcttgatc tcgctgtgat ttcctctcca aagcctgacc
     7201 ttctaatttt gacaaggcac gaacttcttc tatatttatt ttagagcttt ttgctgtaaa
     7261 taccataact catctcctta taaagcaaac ggatacccag taaaaattta cttttcacaa
     7321 gatatccgcc tctaaactat ctcattttat tgtcttttac cgtgacagtt tttaaatttc
     7381 ttaccagaac cacatgggca aagttcattg cgtccaatct ggctcaaatc caaatcttct
     7441 ggcatacttg cttggtgagc agcgatattg cgagtcgctg ttgtactgat atgacgttct
     7501 gcctgtggtc tttcttgttc atgaatttgt gctttcatca tcaagcgtgt cacatcaaac
     7561 tcaatcgaac caatcatatc attaaacata cggaaacctt ctgcctgata ctcaacaaca
     7621 gggttgttct gagcatagcc acgaagtcca accgcgttac gcaattgatc aagggcatcg
     7681 atatgatctg tccacttgtt atccaccact cgtagaatca aaactttttg gaattcttta
     7741 actgcttctt catcgcgtag ttttgaaacc tgactatcgt aaaccttcaa ggaacgttgg
     7801 aaaagctctt ccttgatggc cttatcagac aagcctgaca agtcttccat cgtaatagaa
     7861 tcttcaggaa gcaagttgta cttagcaaag ttcaaaattg cctctagttt ttcatcttgt
     7921 ttggcacgcg catgaccatc aacgacacgt tcaatcgtgc gtttgatcat agactgaatt
     7981 tcaggtgcca agtcacgatc tgcagtgatg acatcgtaac gttgagcata gataatctca
     8041 cgttgttcac gcatgacatc atcgtattga aggacttgtt tacgggtatc gtagttattt
     8101 ccttcgacac gtttctgagc tgcttcaacc tgacgcgtca acatgcgaga ctcaatggcc
     8161 tcttcagaca tgttgagacg ttcaaagatt cccttcaagc gttcagaacc aaaacgtttc
     8221 atcaaatcat cttcaagaga taggtagaat tgtgactcac ctggatctcc ttgacgacct
     8281 gaacgtccac gaagctggtt atcgatacga cgactttcat gacgttctgt accaataaca
     8341 caaagtcctc caagttcacg aacaccttca ccaagcttga tgtcggtacc acgacccgcc
     8401 atgttggttg cgatggtaac ggcaccacgt tgaccagcat tcatgatgat ttgggcttct
     8461 ctatagtggt ttttggcatt caagacttcg tgaggaacac cagctgcaac caatttctta
     8521 gaaatgtagt cactagtttc aaccgctact gtaccaacca agacaggttg acccttttgg
     8581 taacgagcct taacgtcttc gacaaccgct ttaaacttag attcgatact tgcataaaga
     8641 aggtctgagt ggtcaatacg ttgaacagga cggtttgttg ggattggaat aacacgaatg
     8701 ttgtagattt cacgaaattc ttcttcctca gtcttacctg tacccgtcat accagacaat
     8761 tttttgtaca tacggaaaag gttttggtac gtgattgagg cagatgtctt ggtttcatcc
     8821 tggattggca caccttcttt ggcttcaata gcttggtgca atccatcaga ataacgacga
     8881 ccttccatgg tacgacctgt aaattggtcg acaatcaaga tttcttgctc ttcgctcacc
     8941 acatagtcaa tatcgagaag catgatgtag ttggcacgaa gggcgttatc gataaagtgg
     9001 gtcaaagcca cgttttcgat gtcatagagg ttttcaagtt tgaagtagct ttcagccctg
     9061 tcaatccctg aatcagacaa accaatagtc ttagactgca catcgatgat gtagtcatct
     9121 ttgttcaaag attttacata gtggtctgcc atgtgataca actgactggt ttcaaccgca
     9181 ttggcacctg atacaatcaa aggtgtacga gcctcgtcaa tcaagataga gtcaacctca
     9241 tcgaccaagg catagttaag cggacgttgt accatgtttt cagcgcgaac gaccatgttg
     9301 tcacgaaggt agtcaaatcc gatttctgag ttagttgagt aagtaatatc acactcatag
     9361 gcttcttttt tctccattgg agatttggta gccaagttaa tccctactga caaaccaagc
     9421 caagagtaca attcacccat ctcagtcgcg tcacgttctg acaggtattc attaaccgta
     9481 actacgtgaa cccctttacc tgaaagggca ttgaggtata ccggcatggt cgcagttaag
     9541 gttttccctt cccctgtacg catctctggc acgtcaccat ggtgaagaac aatccccccc
     9601 atgacctgaa ccttataagg gaagagacct aggacacgtt tggcaccttc acggacaacc
     9661 gcaaatgctt cgtaaagcaa tgaatccagt gattctccat tttgataacg ttccttaaat
     9721 tcaactgttt ttgcttttag ttggtcgtca gtcaaagcag ccatttggtc ttcgtatttg
     9781 aaaaccttgt cagccatctt ttccagacga cggatttctc ctttatcatt ttcgataatt
     9841 gtttttaaaa tattagccat gtttttcctt actttaaatt ccgaatattt tagaatgttc
     9901 ctttaatttt agcacaatta ctgattattt tcaaggaaga atccccattt tgaaaaggaa
     9961 aaagaggtta gttttcaagc taacctctcc gacttttatg actgtttaat tgccaaaaat
    10021 cggcaaaatg gcaaatgtga taaataagtt aatccaaaga gaaagacagc aaatcagtcc
    10081 aaaaacaaag agactgactt tcttggacag caaggccatg agaatggaca gaattccaaa
    10141 agctagcaag attttctgta tgatgaagat gtcaatcctt acccccagaa tcgctctatc
    10201 ccaagggata aagaagaaag acagccagat cagcagaact aaaccaatat aaaccttgga
    10261 atagcgtgta ataaatgatt ttagatgtgc cataagccat ctcctaggat tgtatatcct
    10321 ttacatttgt atatgtccat tttcgacaac taatacatct gtacaaaggt ctgaaatatc
    10381 ttccgatatg tgcgacgtca ggataaccag accattttct tttttcaggt aagataaaat
    10441 gacctgtttg gttaacctca cactcttctc atccaaagca ttcataggtt catcgagaaa
    10501 gagtatagaa ggagaggaaa taaaggcttg aatcaaggcc attttttgct ttgttcccaa
    10561 ggataaatga cggtattcaa cgtcttcaaa ttcctgtaaa tcatagtatt gaatccaata
    10621 ggcaattctt ttttccgtaa ctttagatga aaaatacctt aacagttcca aattttctct
    10681 cagggataaa tgagataaaa actcgacttt ttcaattaaa attcctgcat cctgaatata
    10741 atgatttttt atcccgtaga ctttcccgtc ttgaagaact tttcctttgt caagcttaat
    10801 atagccagca agtaccttta aaagaaccgt cttgccagat ccattatcac ctttaagtcc
    10861 ataaattttt cctgattgaa acaccaaatt caactgattt aaaataggtc ttttcccata
    10921 aattttctgt ccatttataa tttcaagtct catcgtttat cctttcttaa atttctcttc
    10981 caagcgacta acaatcaaca taactaataa acttaagagt agtaaataca ctgttacaat
    11041 atgatccatc atccattctt gtcccacaaa tactaaaaaa tagagaaaaa aggaaaaacc
    11101 agcgcccgca ctaatcagtg ctatcagata agacagtagt aagtacaaca tcattaactg
    11161 agcaagtaaa aagaaaagtg cgactgtttt gaaatgaatt cctagcggaa gtaaaccaag
    11221 gaaccagaca aacaaatctt gagtaaaaaa tttagaaatg acaaccaatc gtttccttgt
    11281 ataatcgaaa aaggagcttg attgatagcg aatcaagtga tggtaatggt ctgccaaatc
    11341 actttcaagt aaaatgacag agagccatcc taccatgaaa agcgaaaggt ttaacaagag
    11401 tttggggatt tctaaattcg cttcagaata gtcattatag gaaaaaattg aaatcaattc
    11461 tctcttgaaa aagataacag catcctgctt ttgaaccgct gttgacaata gatggtttat
    11521 caaaatcatc atcagaacta tacgaagtag taaaacaatc tttctcttta gcaaaatatt
    11581 gttaaaattc ttaaacatta tcttcatatt tttcaagcac catgtaaggg acaatataaa
    11641 ggatataagg agtaaagagt ttcatcaaac ttacatcccc atagctagct tgcatcaaac
    11701 tcgtcatagg aaccatatag taaggcaagg cactatagag cagcatagaa ccaagccaaa
    11761 gaaacatcaa ataggtgatt gccgaacgag tcacattccc cacataatca actatttgta
    11821 aaaaatagat tgcattgatg aaaataccga ttagcaggac acaagtaaag aacaaatagc
    11881 tttttatctc tccatctagg agtctttgta aaccacttcc atcagaaaat agagaattcc
    11941 atccaagagg agaaaaagtc ccaaggaaat aggttataat tgcaattgtc agcacagtca
    12001 ctaaatatat caaacaaggg atacttgcaa cttgcaaagt caactttctt tttaaccctg
    12061 gatagctcac ttctcttcca atactcaatc gtaaaacttt atttttcagc tcaatatatt
    12121 gaaaacctag caaaacaatg atgattggaa taataaatga ttgataaaaa cctagattga
    12181 actggagaat acgaaaatct aatgctgatt ttaataagtc atttttaatt gcttgtccat
    12241 cgaatttagc tagatcgggc gcatgaatat caaaaaagaa ataagtcatc aaaacgtcac
    12301 gataaaccaa agcaagaaaa agcaaagtaa gcaagacata aacaaattta tgccttgcca
    12361 aagttaagag aggaatcttc ataaattata cctactttac gaattaattt ggtgaccaac
    12421 tacctgaaat ggcagctgat aaatcccacc aattttgtct tgccatatct gctgcataaa
    12481 catagccaac cgttgcccaa ttaccatgag ttgaacgagt accacaggtt gttaacgatt
    12541 ctccactacg agcttctcca ttagaattta ctatacgatg cttaacagtc atgggatgta
    12601 aatttctaca aggatttaag ttcatgatat attccgcacc ttcattttct ttagtcaaat
    12661 aacctgttct cttataactg gtagtaataa caaaattact aaaagcacct atctgatttg
    12721 cttctacgaa agtagttcca acagcactta tcattaaaac aggaataacc attttcaata
    12781 atttcttaat tttcattttt tctgtttcct ttcatttttt attcaagaag attccttata
    12841 acttctattt taaatataga cttattctaa acgatggtat atcatacaaa ttcctccttt
    12901 acttattata tatagactct aatttcttta tccccaaaac catgtttcaa accagataag
    12961 ttgaatccaa ctccaaatca aaaatccaga gtttttcggt aaattcttca aatatttttt
    13021 aaagcccatg actttttccc tcctttttga tataataata ccaccttttt ctacgttttt
    13081 tataaatgta gaaaatattc acatttacct aggaggaaca atatgagatg ggattatgga
    13141 caaattttta aagaaattcg aaagtcaaaa ggattgaccc aacaagatgt atgtggacaa
    13201 gtcatacatc gaacaactct aacaaatatt gaacacggta aagttattcc cagttttgaa
    13261 aacatggtat ttcttcttga acaaattgat atgagcttgg cagaattcaa gtatatatgc
    13321 aacgaatacc atcctagtaa aaggcgagat attattgtag agagccaaaa tccgtctact
    13381 tttcaagata ctagaaaaat ggttgaactc actgagaaat gtcaaaaata tcttaagaca
    13441 catcacgatg ttcctattca aaatatctat cgtcatacaa aaattgtcac agagttacga
    13501 actaaaggat tcaaaaacaa ccacgtcttg aaagatttgt atgaagaaat ttgggactat
    13561 cttgaaccta tggatacatg gtacattagt gatttgaaat tgcttggaac cattctcttt
    13621 ttctttcctt ctgaaaatct tccccttctt attgatagaa ttatgaaaac catcgagaaa
    13681 tataaatact tccgagaaac aaaagcattt ttatcatctt ttttagccaa tctctccact
    13741 gtatattttc aacatcattt attcaaagaa tgtgaaacaa tcaccctaca acttttggta
    13801 ttagcagaag aattaaaaat atacgatatt cttggattct ctcaagtacg cttgggaata
    13861 ctacaacata actccgattt gattgataaa ggaataactt tattacgact aaccaaagaa
    13921 gaggcattag ttaaaatact cgaaaaagaa attaatgatt tttcaaacct ataatttgta
    13981 ataactctca tcattttatt atagtagatt gtaatagaat gtaatagaat gtgaacgaat
    14041 caattagggg atctaaagca ttttatacca atgttttata agttgtattg tattattcca
    14101 tattcaatcc actatacaag atgaatattt ctctcaagtt tcataatcaa aataaaaatg
    14161 actgtatcta tagctccata aacaaatcat agatacagtc attttttagt tcctacacct
    14221 tcctttatgc acacctttag atttccctag ttcccgcctc aagcgaatca tttttttgaa
    14281 aaagacatag gctaaccaat cactagcaaa agcgataagt agtaataata gccaaatacc
    14341 ccataacttg atatctgtca aatttctcaa gacgatattg aaaaacagaa ctgaaaaaac
    14401 tgtccaagca aggctaaaaa gagcatagag ggtgatgtaa atccagtaaa aatagtaaaa
    14461 aattgggaaa aatttacttt ctctattatc cttgtcaatc cagctgaaaa agtaaaaaca
    14521 gggtaataag attatcattt taaacaagtg ttccatcaca agcctccttt tttaaattgt
    14581 tttctttagt ttcgttctat taaatgttat taccaatata aaccttggaa tagcgtgtaa
    14641 taaatgattt tagaggtacc ataagccacc tcctacaaat agaaaccgat ataaatcaat
    14701 gccttccacc cttagacttc cctagttcct gtctcaagcg aaacatttct ttgaaacagg
    14761 aataagttaa ccaattcata ccaatagcta gcagaataaa aagaaaccaa atgccccata
    14821 acttgatatc tgtcacattt ctcaagacgg tattgaaaaa cagaactgaa acaactgtcc
    14881 aagcaaggct aaaaagagaa tagaagggga tgtaaaacca gtaaaaataa taaaaaattg
    14941 gaaaaaactt actatttctg ttggcctttt caatccagtt atcaaaataa aagtacggtg
    15001 ctaaaagtaa gaatttaaac aaatgttcca tcaccgacat cccccttctt ttgatagcgt
    15061 tttctattat tttattatat caaaaaaatc cggaactgtc attccagatt ctactttttt
    15121 atttgcgttt tcttgcgatg agatgaatcg gtgttccctc aaaaacaaag gccttgcgga
    15181 tttgattttc caagaaacgc aggtaagaaa agtgcatgag ttcttcttca ttgacaaaga
    15241 tgacaaaggt tggtggtttg gttgccactt gggtcgcata gaaaatcttg agacgttttc
    15301 ctttgtctgt cggtgttggg ttgatggcaa tggcatccat gatgacatcg ttcaagacag
    15361 ctgatggaat acgtgtattt tgactttcgc tgatttgctt aatcatctca ggaagtttgt
    15421 ggagacgttg cttggttaaa gctgatacaa agataatcgg tgcgtaaggc aggtattgga
    15481 actgctcacg gatatcttct tcccagtttt tcatagtgtg gttatctttt tcaagcgtat
    15541 cccacttgtt gaccacgata atcatccctt taccagcttc atgagcaaat ccagcgatac
    15601 gcttgtcgta ttcacgaatc ccctcttccg cattgatgac cattaagacc acatctgaac
    15661 ggtcaatagc acgcatggca cgcatgacag agtacttctc agtattttca taaaccttac
    15721 cagacttacg cataccagcc gtatcaatca tggtaaactc ttgaccatct gtatctgtaa
    15781 agtgggtatc aatagcgtca cgagttgttc cagcaacagg actggcaatg acacggtctt
    15841 ctcccaagat agcattaatc aagcttgatt ttccaacgtt aggacgacca atcaagctaa
    15901 acttaatgac atctggattt tcttcttcat attcatttgg aaggttttcc acaatcgcat
    15961 ctagtacatc ccctgtaccg ataccatgga cagatgagat aggcagtggt tcacccaaac
    16021 cgagagcata gaaatcatag atatcatttc tcatctcagg gttgtccacc ttgttgactg
    16081 cgaggataac tggtttgtgg gtcttataaa gcttacgagc tacgtattcg tctgcatcag
    16141 taattccttc cttaccagac acgacaaaaa cgataacatc tgcttcttcc atggcaattt
    16201 ctgcctggtg cttgatttgt tccatgaaag gagcatcgac atcatcaatt cctcctgtat
    16261 caatcatgct aaaagaacga ttgagccact cacccgttgc ataaatacgg tcacgtgtca
    16321 ctccttcgac atcttctaca atggagattc gctcaccagc gatccgatta aatagggttg
    16381 atttcccaac attgggacgt cctacaatgg caatagttgg tagggccata atttctcact
    16441 ttctacaata atttcttctg ttcaagattt tttctagttg agcttggttc agcttgacca
    16501 aactgttctg ctaggcgctg actccagctt gtggtcgcac gcgccccagc atagtcagcc
    16561 tgaacacggt cataagcttg gattgcctca gttgactgtt cttggtattc ttcctcaaag
    16621 acaacattct ctagtggcag tctcggtttc atatcatgat gttgatttgg cacacccagt
    16681 gccatcccaa agacagaata ggtgtagtca ggtaggttaa agagctctgc cacttcttca
    16741 gacttgtatc gaaccaaacc gataatcaca ccaccatagc ccaagctttc agctgccaac
    16801 aaggcgtttt gtccagcaag agctgcatcg accgaactaa tcaagagacc ttccacacct
    16861 tggggttgga aggtgtcggt atgaagtctg gctccctttt ctgctcggtt caaatctccg
    16921 acaaagagaa ggaaaacagc agactggcga atggcttctt gaggtaccaa ttcatacaag
    16981 gcatctttct tctcttgact tcgtaccaca atcacagagt aggattggaa attcttccaa
    17041 gatgatgcca tctgggctgc tgtcaaaatc tcatttaagt ctacttgggg aatttcttgc
    17101 tctttaaacc tgcgcactga agtatgagcc ttcatcaatt taatggtttc tgtcatcgac
    17161 ggtttactcc ttctaaacga gtctcctcag ccaaataacg gatgcgttcc atgacccgtc
    17221 tggcttccca ggtttcgtca tttccatgtt tcactttcgc aaaatgcttc tccaaatctt
    17281 caaagttgaa gttggatgtg aaaaaggtcg gtaaattttc ctgcatccga tattggagaa
    17341 tgacctgcag gatttcatca cgcacccaag cggtggattg ctcggcgcca atatcatcta
    17401 aaatcaggac ctcagacagc ttaatctcat ccaccaaggt cttaacattg ccatcactga
    17461 tagcattttt gacatcaatg acaaagctag gatagtggag gagagttgat gaaacaccac
    17521 gtttttctga taaatcatga gctaaggccg ccaccatgaa acttttaccc acaccaaagt
    17581 ctccatataa gtaaagacct tttcgaatag ctggatattg ctccacgaag gctagtagct
    17641 tttcaaaaac tggtaagcgc cccaaatcat ccaagtcaac ttgagccaaa ctagctttct
    17701 tgagactggc tggtagattg attaacttga gacggttctt aatagccgct tctttttcag
    17761 ccgcgattag ctcaggagtt tcttcatatg aaacatctgc atagccatga ttcttaacca
    17821 aaatcggctt gtagcctttg gcaatataat ccgtatcccc acggagaaac ttgtcacgct
    17881 cggtgatgta ctgattaaac ttggagatac tgcgatttaa ttcctctgga gtcaaggatt
    17941 cttgctggat aaaagccgca acatcagggt ccttcatgat tttctggacc aaatcttgat
    18001 aataaaaacg gctgggttga cgtttgagta cgtctccgac actttccatc taatctcctc
    18061 ctttttctaa tcgagctaat agttcttgct tcttacgttc tagttccaga cgagtttcct
    18121 cgctggtttc attcttatat tcaggattac tccatttagg aacattggtt tttactgggg
    18181 cagtctgatt ctgtttttgt gtttttgctt tctgtcctcg ctcacggatg cgcaagactg
    18241 ccttttctgc cgaatgaatc ttttgatagg catagtcatt ggctaccttc atggcatatt
    18301 tctcattgat atttgccgaa tcgaccttat taaaggtcaa taaaagaatg atattgatga
    18361 cttcgtccag caagcccaag ccagccatct gttgcaagag ttctctttct gtttgggtaa
    18421 tggttccctt gcgtgtttgc ttgatttctg ccaagaactg cagggcagtt ttacttttgg
    18481 cttctttgat aatggttgtt tccttaagac taaagtcaga ggaaactggt ttttgagcaa
    18541 ttttttcacg catgcgtttg gttgaaataa cctgagaaac agctgttgac ttggccaatt
    18601 gataggtttc aaaccaagtc catttcttct cctcggcaat agcaaagagg tttaagacat
    18661 cggactgctc atccgcaaaa cgaagtccat ctcgagccat cagccggcga aaatgttcca
    18721 agtcaaaatc attggccact ttcttcttga gaccaaggtc ttcttgactg cctagttctg
    18781 ccaattctgg aaagacttga ttgagtgaga caggtatttc ttcaccatca gcactttcaa
    18841 ctttcaaatc ctccacagca gagtcgccaa tctttttctc taagagtctg cgataaacag
    18901 gatgctccaa gaagtcttga ctagatagag gagcatggag ggctagctga taaacatccc
    18961 ccttttgata gagggtcaag agattaaaag cagataagat tttcaatgat tttatcagtc
    19021 tatccatccc aaagttgaga tgattgagga tacttgaaaa aagatattcc tttctaccat
    19081 tatcccaaaa actgattgta taaagataaa ggctcagtgc ctcctgaccg ataatcggga
    19141 ggtagcactg taccagagat gaggtatctt gcgacacccg attattcttt agataagaaa
    19201 aacggtcaat tggcttcatt tatctttcct ttttcttttt agaggactgg gtgatttgtt
    19261 ggagcaagct ctctaactca ctgacatcct taaaactacg atagacacta gcaaaacgta
    19321 cataggtaat ctcgtccaat tcagccaact cctccatgac gagtgaacca atgtcctcac
    19381 tttgaatttc attttcattt cgaccacgga gtttctgttc gatacgattg actaccatgt
    19441 tgatttcatc acttgacaca ggacgtttct gggctgagcg gataatccca ttaaagattt
    19501 tatctctgga gaattgttcc cgtgtaccat cttttttaac aaccactaag gttctttctt
    19561 ctactcgttc gtaggttgta aaacggtgtt ggcattcgtc gcactcacgt cttctacgaa
    19621 tggtgttccc ttcttctgct tggcgactat cgataacact tgacttggta gccccacatt
    19681 ttggacaacg catcctttcc ctccttatcg ttttcttttc attataccat tttttaagcg
    19741 attcccaaaa caattcttct ttttgcttga caagtttttt gttttgttgt attatttaat
    19801 taagacaaaa ggataagaga aaggagacta agatgtcctg gacatttgac aacaaaaaac
    19861 ccatctattt acagattatg gagaaaatca agcttcagat tgtttcccat acactggaac
    19921 ccaatcaaca acttccaacc gtgagggagc tagctagcga ggctggtgtc aatcccaata
    19981 ccatccaaag agccttatca gaccttgaac gagaaggatt tgtctacagc aagcgaacaa
    20041 ctggacgatt tgtgactaag gataaggagc taatcgccca gtcacgcaaa caattatcag
    20101 aagaagaatt ggaacacttc gtttcctcca tgacccattt tggctatgaa aaagaagaac
    20161 taccaggcgt agtcagtgat tatattaaag gagtttaagc ctatgtcatt actagtattt
    20221 gaaaatgtat ccaaatcata tggagcaaca ccagcccttg aaaatgtttc tcttgacatt
    20281 ccagctggaa aaattgtcgg ccttcttggg ccaaacggct caggaaaaac aaccctgatt
    20341 aaactaatta atggcctctt acaaccagat caaggacgtg tcctcatcaa cgacatggac
    20401 ccaagcccag caaccaaggc cgttgtagct tatttgcctg atacgaccta tctcaatgag
    20461 caaatgaagg tcaaagaagc cctaacctac ttcaagacct tctataaaga tttcaatctt
    20521 gaacgcgccc atcatctact tgcagacctg ggcattgatg aaaatagtcg tctcaagaaa
    20581 ctatcaaaag gaaacaaaga aaaggttcaa ctgattttgg ttatgagccg tgatgctcgt
    20641 ctctatgttt tggacgaacc cattggtggg gtggatccag cagcccgtgc ttatatcctc
    20701 aataccatta tcaacaacta ctcaccaact tctaccgttt tgatttctac ccacttgatt
    20761 tctgatatcg agccaatctt ggatgaaatt gtcttcctaa aagacggaaa agtcgtccgt
    20821 caaggaaatg tagatgatat tcgctacgag tcaggtgaat ccattgacca actcttccgt
    20881 caggaattta aggcctaagc aaaggagatt atttatgttt tggaatttag ttcgctacga
    20941 atttaaaaat gttaacaagt ggtatttagc cctctacgca gccgtgctag tcctttctgc
    21001 cctcatcgga atacagacac aaggctttaa aaatctacct taccaagaaa gtcaggctac
    21061 tatgctactt tttctagcta cagtctttgg tggcttgatg cttacacttg ggatttcaac
    21121 cattttcttg attattaaac gcttcaaagg tagtgtctac gaccgacaag gctatctgac
    21181 tttgaccttg ccagtttctg aacaccatat catcacagcc aaactaatcg gtgcctttat
    21241 ctggtcattg attagcaccg ctgtattggc tctaagtgct gttattattc tggctttaac
    21301 agctccagaa tggattcctc tttcttatgt gattacattt gtagaaacac atctccctca
    21361 gatctttctt acaggtatat ccttcctact aaatactatt tcaggaatcc tctgcatcta
    21421 cctggctatt tccattggac agcttttcaa tgaataccgt acagcactcg ctgttgcagt
    21481 ctacattggt atccaaatcg tcattggatt tattgaactt ttcttcaatc ttagttctaa
    21541 tttctatgtc aattcactgg taggactcaa tgaccatttc tatatgggag caggtatagc
    21601 cattgttgaa gaactcatat tcatagctat cttttatctc ggaacctact acatcttgag
    21661 aaataaggtt aatttgcttt aaataatttt tacctagata tgtaacatac tcatagaaca
    21721 aaagagacca ggcaaaaagt ctttacaatt agaaaacgca tagtatcaag tgttaaaaat
    21781 ccttgatatt atgcgttttt tgtgagctga cttatttcct ttcactatat cgcaaaatga
    21841 aataagaacg gaacgatggg attttggaat tcaaatcaat ttataagaat gttttagaag
    21901 taatattatc ctattccaga ttcagttcac tatacaattg agttttcaag caacctgttt
    21961 acataatgtg tacataatta ggttcgtgat tccacccttt tcacctttaa aaacctcgct
    22021 ttcgcaaggc tcttctattt ataagataag gcacgtttaa aggttttcca aatccctaaa
    22081 tcatccgttt gaagaacgag actagcatac atgcgtccga taaatcctgt tgctaccacc
    22141 gcaaaaatca ctgtaatagc aagtgaaatc catgcttccg ctccctccgc atagccatta
    22201 atcgttcgaa acggcataaa gaaggtcgaa ataaagggaa tataagaacc aatcttcaag
    22261 aggagattgt caccagctgc acctagagct gtcactccaa aaaaaccacc cataatcaaa
    22321 atcatcaaag gcgacaaggc tttccctgag tcttcaggac gagaaaccat agatcctagg
    22381 aaggctgcca agactacgta catgaaaaga ctgatcaaaa taaagagcaa ggtattcagt
    22441 gagatagcat ctcccaagtg atccaaaata ccagactgag ccaagaatgg caaatcttta
    22501 aagagcaaaa cggcagccag accacctaca acatagatcc caatatgcgt taaaatcact
    22561 agaaacagag ccatcatccg cgcatagaaa tagtgacttg cccttatgct agaaaagacg
    22621 acttccataa ttttggtgcc tttttcactg gcaacttcct gagctgttac acccgcatag
    22681 gtaatcagaa tcatataaag aaagaatcct aaggcacctg ctgcaattgt ttgaataaac
    22741 tttttatttt ccttggcttc atcaatcttt tctgtgaatt gaattgtctg cgctaagcgt
    22801 ttttcctgct cttgagacaa ggaagcagtt gaacgattaa gctgattttg cagttcattg
    22861 agtgtacctg taacctcaaa tttaattcca ttttcaagcg atgtttcgcc atgataaact
    22921 gcctttagaa cactatcttc ttgatcaatg gtcaaataac cttttaattt ttcttcttta
    22981 attgcttctt tggcacttgc ttcgtcttta tagtcgaagt taacaccatt tacattcttc
    23041 agtccttctg ctacagatgg cactgttgtc actactgcca ctttattatt tttagccata
    23101 gaagaacctt ggagatgccc aattcctaca gagattccta aaaagaggaa cggcgaaatc
    23161 accataaaga agaaactcca tgactcgaca tgtcgaagat aggtttcctt gattacaacc
    23221 cacatatttc tcatacttcc actcctgatt ctagtttaaa gatttcatcg atagttggcg
    23281 cttgttggtc aaatgttgcg atatattgac cttgagtcaa gattgggaag agttcccttc
    23341 cagcgctctc atcctccaaa atcaatttcc aactgccttg tttggtcaag ctcacctgtt
    23401 tgacatgagg aagattttcc aattcttcct tgcttcgttc acttgaaaca aagagacgcg
    23461 ttttcccgta ttgattgcgg acatcctgaa ctggtccgtg caagaccaca cggccatctc
    23521 gaatcatcag aatatcgtca caaagttcct caacattggt catgacatgg tcagaaaaga
    23581 taatggttgc tccgcgctct ttttcctgaa aaatgacttg tttgagcaat tctgtattaa
    23641 ctgggtccaa tccactaaaa ggctcatcca agataatcag gtctggttca tgaatcagag
    23701 taataatgag ctgaatcttc tgctgatttc cttttgacag actcttgatt ttatctgtca
    23761 gctttccttt tacttccaac ctcttcatcc attgagggag tttttctttg acttctttgg
    23821 catccatgcc ttttagagtc gccaagtagc gaacttgttc aagaactgtc aatttaggca
    23881 tgagactgcg ttcttcaggc agataaccaa tccgagcata gatctcctga cgaatatcct
    23941 gaccatccag accgatttct ccctgatatt ctaggaattt taaaatacta tggaaaatcg
    24001 ttgtttttcc agcaccattt tttccgacta gtcccaaaat acgacctggt cgcgcttgaa
    24061 agtcaatacc aaacaaaact tgcttggatc caaaactttt ctctagactt cttacttcta
    24121 gcatctttca cctccgaaat ttcttgcact cattatactc ctttttgata gcctttacaa
    24181 tgttttttgt ccatttttag aagactattg ctgtgtaaaa tatggcctgg agcactttta
    24241 tactcaatga aaatcaaaga gcaaactagg aagctagccg tagactgctc aaagtacagc
    24301 tttgaggttg cagataaaac tgacgaagtc agctcaaaac actgttttga ggttgtggat
    24361 agaactgacg aagtcagtaa ctatacgtac ggcaaggcga agctgacgtg gtttgaagag
    24421 attttcgaag agtattagtg ataaatccat tatacagcag caaacttaat ttataccttc
    24481 cgctcctcaa ctgtctattt ttaatcctga attgttattt gagtaactcc tttttcctcg
    24541 taaagttttc ttcctctaaa acttctggaa aaaggctaat agtttcagac aacattttta
    24601 taagaaacaa gttcatctgt catttcaaga aggagtaatc ctttatctac taatggacgg
    24661 aacagaattc aaccgcttgt ccgatatgtt ttctaaggat tatatagtaa aatgaaataa
    24721 gaacaggaca aattgatcag gacagtcaaa ttgatttcta acaatgtttt agaagtagat
    24781 gtatactatt ctagtttcaa tctgctatat ctattatgca cacccctata ggatctaatg
    24841 aaaatcacaa caggctcatt catagatagt tacctcagga aactaagaaa acgactacaa
    24901 aggaagtcgc attcatcgaa aagtggatta acaactatcc taaaaaatgc ttgaactaca
    24961 agtcccccag agaagacttc tggatgacta acttgaactt gaaatttagc aataattaat
    25021 tcaccatcta actatattta gtaattattt cagaactgat taatattaaa attaactaac
    25081 aattcaaagg attcatacta gccataaatt acgtccatca gagagagact cttactactt
    25141 ttagatttta gtctttctag cttcagaata catctaaact ttagggaaaa tgactattcg
    25201 aaagcgcgaa tgcctcaaaa ttatctcaga taagctattc gaaacttaga atgcttttaa
    25261 atttatggaa ttgcgattat tcgaaaccta gaatgcatat aacctttagt tgacagacct
    25321 attctaagtc tcgaagggct atttactttc tattccttat caaaaaagac tcattccccc
    25381 tttctcctcc aaaatatggt atagtagaaa tatactatct atgaggagtt tacatgtcac
    25441 aggataaaca aatgaaagct gtttctcccc ttttgcagcg agttatcaat atctcatcga
    25501 ttgtcggtgg ggttgggagt ttgattttct gtatttgggc ttatcaggct gggattttac
    25561 aatccaagga aaccctctct gcctttatcc agcaggcagg catctggggt ccacctctct
    25621 ttatcttttt acagatttta cagactgtcg tccctatcat tccaggggcc ttgacctcgg
    25681 tggctggggt ctttatctac gggcacatca tcgggactat ctacaactat atcggcatcg
    25741 tgattggctg tgccattatc ttttatctag tgcgcctata cggagctgcc tttgtccagt
    25801 ctgtcgtcag caagcgcacc tacgacaagt acatcggctg gctagataag ggcaatcgtt
    25861 ttgaccgctt ctttattttt atgatgattt ggcccattag cccagctgac tttctctgta
    25921 tgctggctgc cctgaccaag atgagtttca agcgctacat gaccatcatc attctgacca
    25981 aaccctttac cctcgtggtt tatacctacg gtctgaccta tattattgac tttttctggc
    26041 aaatgctttg acacgtaaaa aatccgtttg gtttcccaag tggattttta aagcgtagat
    26101 taactatagc ttgatactaa atatactttg gtatggaaat catgcatatt tttcgatagt
    26161 gaagcgagga cttacctagc ctttccaccg tgatagaaac acctgaaatc taatggtttc
    26221 aggtgttcgg aaactttgag cctagtgtct caaagtttag gtatggaatt tcgaagaaag
    26281 tcgctaccgt ccgtaatcac ttaaggaaag gctcaaaaat attgttttca accacaaaat
    26341 ccgtttggtt tcccaagcgg attttgtgct ttattttgaa acttcttttg caagaacaaa
    26401 gttcccaagt gtggcagaac catttcctgc gactgctggc gtcacgatat agtcacgcac
    26461 atctggtact ggtaggtaac cattaagaag agatgtaaat ttctcacgga cacggtccag
    26521 catatgttgt tgagccatga cccctccacc aaagacaatc acgtctgggc ggaaagtcac
    26581 tgtcgcatta accgcagctt gagcgatata gtaggcttga acatcccaaa cagggttgtt
    26641 gagttcaata gtttccccac gtacacctgt acgagcttcc aaacttggac cagctgcata
    26701 gccttccaga catcccttat ggaaaggaca aacaccctta aactcttttt caatatccat
    26761 tgggtgtcta gcaacataat aatgacccat ttcagggtga cccacaccac cgataaactc
    26821 accacgttgg atgacgcctg caccgatacc tgtaccgatt gtgtagtaaa ccaagttttc
    26881 gatacgacca ccagcattgt tacgggcaac cacttcaccg taagcagagc tgtttacgtc
    26941 tgttgtgaag tacattggca cgtttagggc gcgacgaagg gcaccaagca agtccacatt
    27001 tgcccagttt ggttttggag tcgtcgtgat aaagccataa gtttttgagt ttttgtcaat
    27061 atcaatcggc ccaaatgaac caactgcaag accagcaagg ttatcgaatt ttgagaagaa
    27121 ctcaatggtt ttatcgattg tttcgattgg agttgttgtt ggaaattgtg ttttttctac
    27181 aacgttaaag ttttcatcac cgacagcaca gacaaacttt gtaccgccag cttccaagct
    27241 tccatataat tttgtcatga taaacctctt gtttttattt tctttattat agcatacttc
    27301 gaaagtctaa atgtctctat tttttagatt ttcctctgta aatcttacta tctaataaaa
    27361 acgaacaaac atgtcatttg ttcgttttca cattagagag gattgattag attttcactt
    27421 cgatcacagc atcccccttc gcaactgaac ctgttgcgac tggagctact gaagcgtagt
    27481 cagctgtatt tgtaacgata accattgttg tatcatcaag tccagctgta gcgattttat
    27541 ttgagtcaaa tgttccaaga acatcgccaa ctttcacctt atcaccttga gcaacttttg
    27601 cttcaaaacc gtcaccgttc atagatacag tgtcaatacc aacatgaatc aaaacttcag
    27661 caccatttct tgttttcaaa ccaaaagcgt gccctgttgg aaaggcaatt gaaacttcag
    27721 catcagctgg tgcatagacc acgccttggc ttggtttcac agcgatacct tgtcccatag
    27781 ctccacttga gaagactggg tcattgacat cagcaagagc gacaacatca ccgacgatag
    27841 gagttacaag tgtttcattt tgaagagctg ctggcgcaac ttcttctttt tcttcagcca
    27901 cttcagcttg ttttgcagct gcagttgcgt ctacttcatc ttcgtaacca aacatgtaag
    27961 taagagcaaa accaagggca aatgatacag ctaccataag aaggtattgt ggaagttgtc
    28021 cgttaccaac ataaagcatt gtaccaggga tgatggtgat accattacca gtaccagcaa
    28081 gtccaaggat agaagccaat ccaccaccga ttgcaccagc aatcaatgaa aggaagaatg
    28141 gtttacggaa gcgcaagttc accccgaaga tagcaggctc tgtaatacct aggaaggcag
    28201 aaagagcagc cgggaaagca agtgttttca gttttggatt ttttgtttta acaccaaccg
    28261 caacagtagc agcaccttga gctgtcatag cagctgtgat gatagcgttg aatgggttag
    28321 catggtcagc agcaagtaat tgcacttcaa gcaagttgaa gatgtggtgc acacctgaca
    28381 cgacgatcaa ttggtgaacc ccaccaatca agaaaccacc aagaccaaat ggcatgctaa
    28441 gaatcgcttt tgtagcaata aggatgtagt tttcaacaac gtggaaaact ggtccaatga
    28501 caaagagtcc aaggatagac atgaccaaaa gtgtcacgaa tggtgttacc aagaggtcaa
    28561 tgacatctgg aacaaccttg cggacagctt tttcaaattt agctccgaca accccgatga
    28621 tgaaggctgg aagaacggaa ccttgcaaac caacaacagg gatgaaacca aagaagttca
    28681 tcgctgttac ttcaccacct tgagcaactg cccaagcgtt tggaagtgag ccagagacaa
    28741 gcatcatacc aagaacgata ccaacggcag gatttccacc aaatacacgg aaggttgacc
    28801 acacaaccaa acctggcaag atgatgaagg ctgtatctgt caagatttgt gtgtaagttg
    28861 caaagtcacc tggaagtggc atttcaagag cgttgaaaag accacgcaca cccatgaaga
    28921 gacctgtcgc tacgataact gggatgattg gaacgaaaac atcaccaaaa gtacggatag
    28981 cacgttggaa ccagttccct tgtttagcaa cttctgcttt catgtcatcc ttagatgatg
    29041 ttggtaatcc aagtacaaca acttcatcgt acattttgtt aactgtacct gtaccaaaga
    29101 taatttggta ttgccctgag ttaaagaaag caccttgaac tttttccaag ttctcaatca
    29161 cttctttatt gattttctct tcatctttga ccatgacacg tagacgtgtc gcacagtggg
    29221 caacactatt gacattttca cgtccgccca aggcatcgat gacttttttt gcaatttcct
    29281 gattgttcat ttgcaaaaat ctccttatat aacattttgt tcttgtttga aagcgatttt
    29341 attcgccctt acgactatta ttttatcatg ttttaaaaat atgtcaagcg ttttgcagaa
    29401 aaaatattct atctacttag tgggcaagct ttagattgat tgtttttgac tgtttcatca
    29461 ggaatttctt gaaaaataag tttgaaacct tggttaaaaa gtcttttatt tcattatctt
    29521 tcacattttc gtaaaaattt gattgatttc ctgtatttat tttatgataa tcgtttgaca
    29581 gttttttctc ttttttaaca taaagggctt gcatttttta tcgaaaacag ttactattaa
    29641 aagtgataag atttttggag gaatgaatgg aatggacaac tgagcgtcgt tacagacttt
    29701 atcaagattg gacgcaagaa gaaattcaac atataaagga aaatatggca caatctccat
    29761 ggcatactca ttaccatgtt gagccaaaaa caggacttct caacgaccca aatggctttt
    29821 cttactttga tggcaagtgg atcctctttt accagaattt tccttttggt gcagcccacg
    29881 gtttaaaatc ttgggcacag ctagaaagtg atgatttggt tcactttaga gaaactggag
    29941 tcaaagtttt gccagatact ccattagata gtcacggtgc ctactctggt tctgccatgc
    30001 aatttggcga taacttattc ctattttata caggaaatgt tcgcgatgaa aactggatcc
    30061 gtcacccata ccagatcggt gctttgatgg acaaggaggg taagattaca aagattgaca
    30121 agatcttgat tgaccagcca gcagactcta ctgaccactt ccgcgatcca caaattttta
    30181 actttaaagg tcaatactat gctgtcgtcg gtggacagga cttggagaaa aaaggcttcg
    30241 tccgtctcta caaggctgtc aataacgact acacaaactg gcaagcagtt ggcgaccttg
    30301 actttgctaa cgaccgtact gcctacatga tggaatgtcc taatctggtc tttgtagagg
    30361 aacagcctgt ccttctctac tgtccacaag gattggataa gaaagttcta gactacgata
    30421 atatctttcc aaatatgtat aagattgggg cttcctttga ccctaaaaat gccaaaatgg
    30481 tagatgtgtc tcaacttcaa aacatggatt acggtttcga agcctatgca actcaagcct
    30541 tcaacgctcc tgatgggcgt gctctagcag ttagctggct tggtttgcca gatgtttctt
    30601 acccatctga ccgttttgac caccaaggaa ccttctcttt ggtcaaggaa ctcactatca
    30661 aagacgacaa gctctaccag tatccagtcg ctgctattaa ggaccttcgt acttctgaag
    30721 aagccttctc aaaccgttcc caaaccaaga acacttacga acttgaactc aacttggaag
    30781 ctaatagcca gagcgagatt gtcttacttg ctgataaaga aggtaaggga ctttcaatca
    30841 actttgacct tgtaaacggt caagtgacag tggatcgtag ccaggctgga gagcagtatg
    30901 cccaagaatt tgggataact cgttcttgcc ctatcgagaa tcaggctact actgctacaa
    30961 tcttcatcga taactctgtc tttgaaattt tcatcaataa aggagaaaaa gtattttctg
    31021 gtcgtgtctt cccacatgcg gaccaaaatg gtatcctgat caaatctgga aacccaactg
    31081 gaacttacta tgaattagat tatggtcgca aaactaactg atgtcgccaa acttgcaggc
    31141 gtcagtccta ctaccgtttc tcgggttatc aataaaaaag gatatctatc tgagaaaacc
    31201 atccaaaaag tcaatgaagc catgcgagaa ttgggctata aacccaacaa cctggctcgt
    31261 agtctgcaag gaaaaccagc taagttaatc ggcttgattt tccccaatat ttccaatgtt
    31321 ttctatgcag aattgattga taaattggaa caccaactct tcaaaaatgg ttacaagacc
    31381 atcatctgca acagtgaaca tgattctgag aaggaacgtg aatacatcga aatgttggaa
    31441 gccaatcagg tggacggcat catttctggt agtcacaacc taggaatcga agactacaat
    31501 cgtgtgacag cgccgattat ttcctttgac cgaaacctat cgccagacat ccctgtcgtc
    31561 tcctctgaca actatgctgg tggggttctt gctgcccaaa ccttggtcaa gacaggtgcc
    31621 cagtctatca tcatgattac agggaatgac aattccaatt cgccaaccgg actgcgccac
    31681 gctggttttg catccgtact cccaaaagct cctattatca atgtttccag tgacttttct
    31741 cccgtcagaa aagaaatgga aatcaagaat atcttgaccc gggaaaaacc agatgccatt
    31801 tttgcttcgg atgatttgac agctattctg gtcattaaaa tcgctcaaga attgggcatt
    31861 tctgtcccaa aagagctcaa ggtcatcggc tatgatggga cctactttat cgaaaattac
    31921 taccctcaat tggctactat caagcaacct ttggaagaga ttgcttgtct cactattgat
    31981 cttctcttgc aaaagattga aggcaaggaa gtcgccacaa ctggttactt cttaccagtt
    32041 acgctattac caggaaaaag tatttaaaca caagaaaact cagaccgatt cgtctgagtt
    32101 tttatgatct taaattttcg agatagcgct gggctgtctc taggttaaag gttttatctg
    32161 agatgaggcg ctctactagg ggagcaactt cagattcact agccccagct aggagagcta
    32221 gggatttggc ctgtagtttc atgtggcctt gctggatgcc cgtacttacc aaggctttga
    32281 gggctgcaaa attttgagca agcccgatag acacgataat ctgggctaat tctctggcag
    32341 aaggatttcc tagtagatca tgactgagag ctacacgtgg gttgaggccg atagagccac
    32401 ccttagtcgc tacaggcatg ggcagggtca tctcaccgac caattcttct ctttcaaggt
    32461 ccagcgtcca gcagctaaga ccttgatagc gtccatctcg actggcaaag gcatgggccc
    32521 cagcttcgat ggcacgccag tcattaccag tggcaatcaa aatcgcatca ataccattaa
    32581 aaattccttt attatgagta gcagctcggt aaggatcagc ctgcgcaaac tgactagcca
    32641 acgcaatttt ctccgcaatc tctcgtcctt gatccttttg gcggctcaag tagcgaaagg
    32701 cgatgcgaca gcttgcagtc accagagaat cagtcgcgta gttggacagg attcccatga
    32761 gactctgtcc ctgactgagt tcttctaaga ctggtttcaa ggcttccagc atggtgttga
    32821 gcatattggc acccatggct tcctgggtat cgacatgaat ataaacaacg agaaagtctg
    32881 gttcgccttt tatctgctcg acatgcagat cacgcgcccc acccccacgt ttaacgatag
    32941 aaggataggc ttgattggca agctccaaga gctccgcttt cttgctggca atcttctctt
    33001 gcgctagttt aggattagca acttgataaa gggctacctg cccaatcatc tggcgctgat
    33061 ggacttgtgc agtaaaacca cctgcacgct tgatgatttt gctggcatag ctggccgccg
    33121 caaccacaga gggttcttct gtcacatagg gaacggtgta ttcctgaccg ttgacaagta
    33181 cctccggaac cagcgaataa ggcagagaaa aagttcccac cacattctca ctcagctggt
    33241 ctgccacagt cacactcatc tgttcatcct tctccagact agcttgtctc tcaggactaa
    33301 ggagcgcctg agcttttagc agctcgaggc gctcttggta tgatttttta gaaaatccat
    33361 tccaacttat cttcattatt tttcaacctt gctataacgg cgttggtggt caagaatttc
    33421 aaccaaggca aaatcttgat tttcatagcc agcaaactgg gcagagtttg tttcatccaa
    33481 gtttacttcc tcaaaaaaga ccttttcata gtctgcaacg gatagggcag ttcgttggtt
    33541 gagcttgttc aagcggtctt tatccaaata agcttcatat ccttcaacca attcaccact
    33601 gaagaactca gccacagctc cacttccgta actataaagg gcgattttat ccccagcttt
    33661 caagctatct gtattttcca agagagacaa aagtccaagg aaaagtgaac ctgtgtagat
    33721 attccccacc ttttgactgt agagaataga ctggtcaaaa tgcttttgca agaggtcttt
    33781 tttctcttga ggcaagttct tatccatgat ttttttcaag ccttttagcg ctaatttagg
    33841 ataaggcaag tggaaacaaa cagccgcaaa atcatccaaa gtaagctggt agcgtttttg
    33901 atattcaagc caagtcgttt tcaaactatc caagtattgt tgggtagaat agacaccatt
    33961 tacataagga gttgtcgagt aatttggtcg ccagaaatcc atgatgtcac gggtctgagc
    34021 tacattgtca ttattaaagg ccatcatgcg tggattttgt gtaatcaaca tagctacact
    34081 tccagcacct tgagttggtt ctcctggagt ttcaataccg tatttggcaa tatcactggc
    34141 aatgaccaag accttggact ccggagaatt ttccacatgc aatttggcat aatggagggc
    34201 agcagtcgct ccgtagcagg cttctttaat ctcgaaacta cgagcaaagg gctggatgcc
    34261 cagcaagcca tgcacaaaga cggccgcagc cttactctgg tcaattcctg actcggtagc
    34321 cacaatgacc atgtcaactt cttgtctttc ttgctcagtt aaaatagagt cactagcact
    34381 ggccgccaag gtcacgatgt cctcagttag gggcgcaata ctcaattcct tgagtaagag
    34441 tcctttactt aatttttcag ggtcaattcc cctcgcttct gctaagtctt gtaatttcaa
    34501 gacatattga ctggtcgcaa aaccaatctt atcaataccg attgtcatat ttacctctgt
    34561 tttatcattc atgtaaaaaa tcgttctata ctattttatc acaaatggca gtaaaagaga
    34621 gaaaaaagac ttgattcacc aaatcaagcc tcttattggt catcatttta aagaatgatt
    34681 agttgctaga gagttcaccg atataagtag ctttataagc tccattcaca gttatcagct
    34741 cctggaggat caaatttcct gagtaaatcc ttcccatctc atctacaaat ttttgataaa
    34801 actgactgat cggaatttct ctgacatcct tatcaaatgt cttatcaagt gttttactaa
    34861 ccttctcagc aatcaattga tgctcttgcc atccactttg aaactctgag cccgaactag
    34921 aaaccatgac tgggataaac aacaaggtca gtagatttac agacaataag gaaagtagta
    34981 gacttcctgc aaaactagaa tcctagttca tga
//
LOCUS       DAVHTH010000017        34464 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.017, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000017 DAVHTH010000000
VERSION     DAVHTH010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34464)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34464)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34464
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.017"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            complement(150..1136)
                     /locus_tag="VVR63_000869"
     CDS             complement(150..1136)
                     /locus_tag="VVR63_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU6128900.1"
                     /translation="MPVTIKDVAKAAGVSPSTVTRVIQNKSTISDETKKRVRKAMKEL
                     NYHPNLNARSLVSSYTQVIGLVLPDDSDAFYQNPFFPSVLRGISQVASENHYAIQIAT
                     GKDEKERLNAISQMVYGKRVDGLIFLYAQEEDPLVKLVAEEQFPFLILGKSLSPFIPL
                     VDNDNVQAGFDATEYFIKKGCKRIAFIGGSKKLFVTKDRLTGYEQALKHYKLTTDNNR
                     IYFADEFLEEKGYKFSKRLFKHDPQIDAIITTDSLLAEGVCNYIAKHQLDVPVLSFDS
                     VNPKLNLAAYVDINSLELGRVSLETILQIINDNKNNKQICYRQLIAHKIIEK"
     gene            complement(1146..1946)
                     /locus_tag="VVR63_000870"
     CDS             complement(1146..1946)
                     /locus_tag="VVR63_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HEU6128901.1"
                     /translation="MLPYPFSFFSSILGFRKPLSKRFGLNWFQLLFTSIFLISLSMVP
                     IAIQNSSQETYPLETFIDNVYEPLTNEVVQDLSEHATIVDGTLTYTGTVSQASSVVIG
                     PSQIKELPKNLQLHFDTNELVISKESKELTRISYRAIQTESFKSKDSLTQAISKDWYQ
                     QNRVYISLFLVLGASFLFGLNFFIVSLGASLLLYITKKSRLFSFRTFKECYHFILNCL
                     GLPTLITLILGLFGQNMTTLITVQNILFVLYLVTIFYKTHFRDPNYHK"
     gene            complement(2199..3041)
                     /locus_tag="VVR63_000871"
     CDS             complement(2199..3041)
                     /locus_tag="VVR63_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001065636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU6128902.1"
                     /translation="MNNSIKLKRRLTQSLTYLYLIGLSIVIIYPLLITIMSAFKAGNV
                     SAFKLDTNIDLNFDNFKGLFTETLYGTWYLNTLIIALITMAVQTSIIVLAGYAYSRYN
                     FLARKQSLVFFLIIQMVPTMAALTAFFVMALMLNALNHNWFLIFLYVGGGIPMNAWLM
                     KGYFDTVPMSLDESAKLDGAGHFRRFWQIVLPLVRPMVAVQALWAFMGPFGDYILSSF
                     LLREKEYFTVAVGLQTFVNNAKNLKIAYFSAGAILIALPICILFFFLQKNFVSGLTSG
                     GDKG"
     gene            complement(3043..4335)
                     /locus_tag="VVR63_000872"
     CDS             complement(3043..4335)
                     /locus_tag="VVR63_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000414940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU6128903.1"
                     /translation="MEKQQPSKAALLSIIPGLGQIYNKQKAKGFIFLGVTIVFVLYFL
                     ALATPELSNLITLGDKPGRDNSLFMLIRGAFHLIFVIVYVLFYFSNIKDAHTIAKRIN
                     NGIPVPRTLKDMIKGIYENGFPYLLIIPSYVAMTFAIIFPVIVTLMIAFTNYDFQHLP
                     PNKLLDWVGLTNFTNIWSLSTFRSAFGSVLSWTIIWALAASTLQIVIGIFTAIIANQP
                     FIKGKRIFGVIFLLPWAVPAFITILTFSNMFNDSVGAINTQVLPILAKFLPFLDGALI
                     PWKTDPTWTKIALIMMQGWLGFPYIYVLTLGILQSIPNDLYEAAYIDGANAWQKFRNI
                     TFPMILAVAAPTLISQYTFNFNNFSIMYLFNGGGPGSVGGGAGSTDILISWIYRLTTG
                     TSPQYSMAAAVTLIISIIVISISMIAFKKLHAFDMEDV"
     gene            complement(4446..5717)
                     /locus_tag="VVR63_000873"
     CDS             complement(4446..5717)
                     /locus_tag="VVR63_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000095461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEU6128904.1"
                     /translation="MSSKFMKSTAVLGTVTLASLLLVACGSKTADKPADSGSSEVKEL
                     TVYVDEGYKSYIEEVAKAYEKEAGVKVTLKTGDALGGLDKLSLDNQSGNVPDVMMAPY
                     DRVGSLGSDGQLSEVKLSDGAKTDDTTKSLVTAANGKVYGAPAVIESLVMYYNKDLVK
                     DAPKTFADLENLAKDSKYAFAGEDGKTTAFLADWTNFYYTYGLLAGNGAYVFGQNGKD
                     AKDIGLANDGSIVGINYAKSWYEKWPKGMQDTEGAGNLIQTQFQEGKTAAIIDGPWKA
                     QAFKDAKVNYGVATIPTLPNGKEYAAFGGGKAWVIPQAVKNLEASQKFVDFLVATEQQ
                     KVLYDKTNEIPANTEARSYAEGKNDELTTAVIKQFKNTQPLPNISQMSAVWDPAKNML
                     FDAVSGQKDAKTAANDAVTLIKETIKQKFGE"
     gene            6267..7784
                     /gene="malQ"
                     /locus_tag="VVR63_000874"
     CDS             6267..7784
                     /gene="malQ"
                     /locus_tag="VVR63_000874"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HEU6128905.1"
                     /translation="MKKRQSGVLMHISSLPGAYGIGSFGQSAYDFVDFLVRTKQRYWQ
                     ILPLGATSYGDSPYQSFSAFAGNTHFIDLDILVEQGLLEASDLEGVDFGSDASEVDYA
                     KIYYARRPLLEKAVKRFFEVGDVKDFEKFAQDNQSWLELFAEYMAIKEYFDNLAWTEW
                     PDADARARKASALESYREQLADKLVYHRVTQYFFFQQWLKLKAYANDNHIEIVGDMPI
                     YVAEDSSDMWANPHLFKTDVNGKATCIAGCPPDEFSVTGQLWGNPIYDWEAMDKDGYK
                     WWIERLRESFKIYDIVRIDHFRGFESYWEIPAGSDTAAPGEWVKGPGYKLFAAVKEEL
                     GELNIIAEDLGFMTDEVIELRERTGFPGMKILQFAFNPEDESIDSPHLAPANSVMYTG
                     THDNNTVLGWYRNEIDDATREYMARYTNRKEYETVVHAMLRTVFSSVSFMAIATMQDL
                     LELDEAARMNFPSTLGGNWSWRMTEDQLTPAVEEGLLDLTTIYRRINENLVDLKK"
     gene            7810..10068
                     /locus_tag="VVR63_000875"
     CDS             7810..10068
                     /locus_tag="VVR63_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000950172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan phosphorylase"
                     /protein_id="HEU6128906.1"
                     /translation="MLSLQEFVQNRYNKTIAECSNEELYLALLNYSKLASSQKPVNTG
                     KKKVYYISAEFLIGKLLSNNLINLGLYDDVKKELAAAGKDLIEVEEVELEPSLGNGGL
                     GRLAACFIDSIATLGLNGDGVGLNYHFGLFQQVLKNNQQETIPNAWLTEQNWLVRSSR
                     SYQVPFADFTLTSTLYDIDVTGYETATKNRLRLFDLDSVDSSIIKDGINFDKTDIARN
                     LTLFLYPDDSDRQGELLRIFQQYFMVSNGAQLIIDEAIEKGSNLHDLADYAVVQINDT
                     HPSMVIPELIRLLTARGIDLDEAISIVRSMTAYTNHTILAEALEKWPLEFLQEVVPHL
                     VPIIEELDRRVKAEYKDPAVQIIDESGRVHMAHMDIHYGYSVNGVAALHTEILKNSEL
                     KAFYDLYPEKFNNKTNGITFRRWLMHANPRLSHYLDEILGDGWHHEADELEKLLSYED
                     KAAVKEKLESIKAHNKRKLARHLKEHQGVEINPNSIFDIQIKRLHEYKRQQMNALYVI
                     HKYLDIKAGNIPARPITIFFGGKAAPAYTIAQDIIHLILCMSEVIANDPAVAPHLQVV
                     MVENYNVTAASFLIPACDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIAE
                     LVGEENIYIFGEDSETVIDLYAKAAYKSSEFYAREAIKPLVDFIVSDAVLAAGNKERL
                     ERLYNELINKDWFMTLLDLEDYIKVKEQMLADYEDRDAWLDKVIVNISKAGFFSSDRT
                     IAQYNEDIWHLN"
     gene            complement(11112..11684)
                     /locus_tag="VVR63_000876"
     CDS             complement(11112..11684)
                     /locus_tag="VVR63_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6128907.1"
                     /translation="MNKLMKFISVFLTSIVLIVSAIPSVSAVYASEQVSQIETNMELQ
                     PVTSLTEEQINTLANEIQSFHPDVSQQWIKEVINRQLQGDYTIPPTYSPFRAAWQGIT
                     VNQMGALLDTAIALALGGTTAGLANLIKVKGKHAAKSAIRSAISRYLGSWFVNDVALE
                     FAMNLLSPGTYLAQLWDKNDAIPNNGRINF"
     gene            complement(12306..13154)
                     /locus_tag="VVR63_000877"
     CDS             complement(12306..13154)
                     /locus_tag="VVR63_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEU6128908.1"
                     /translation="MNTNLKPKLQRFASATAFACPICQENLTLLETNFKCCNRHSFDL
                     AKFGYVNLAPQIKQSANYNKENFQNRQQILEAGFYQAILDAVSDLLASSKTTTTILDI
                     GCGEGFYSRKLQESHSEKTFYAFDISKDSVQIAAKSEPNWAVNWFVGDLARLPIKDAN
                     MDILLDIFSPANYGEFRRVLSKDGILIKVIPTENHLKEIRQRVQDQLTNKEYSNQDIK
                     EHFQEHFTILSSQTASLTKTITAEQLQALLSMTPLLFHVDQSKIDWSQLTEITIEAEI
                     LVGKAF"
     gene            13306..13584
                     /locus_tag="VVR63_000878"
     CDS             13306..13584
                     /locus_tag="VVR63_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003075836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6128909.1"
                     /translation="MLKEVLTVAKVAKKSSLFLGGVAFGTLGLKILASKEAKKGYSKA
                     LAKAYKLKDELDASVSVVKQHGDDVLQDAKYLYEQEKKEEQLDSLIGE"
     gene            13586..15649
                     /locus_tag="VVR63_000879"
     CDS             13586..15649
                     /locus_tag="VVR63_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEU6128910.1"
                     /translation="MSFKVLHRGYQHIRLSSSFSLTLDIQDYLRSLARDEKGIESIQF
                     YMDQQHFTLRIKEGFSVLDNAEAFLKRIDKGKVSELMTLPIRREESAYSIVSGAAVKR
                     VLFRSFVPYPIRYIWTCYQALGYIREAYQTLARKELTMEVLDCSAILLSLFMNQSKTA
                     SNIMFMLDLGNHLDQWSLKKTATDLEQSLLAKESDVFLVQGDTVVSIKSSDVQIGDVL
                     ILSQGNEILFDGQVVSGLGMVNESSLTGESFPVEKRESDLVCANTVLETGELRIRVTD
                     NQMNSRILQLIELMKKSEENKKTKQRYFIKMADKVVKYNFLGAGLTYLLTGSFSKAIS
                     FLLVDFSCALKISTPVAYLTVIKEGLNREMVIKDGDVLEKYLEVDTFLFDKTGTITTS
                     YPIVEKVLPFGDYSEEDILRISACLEEHIYHPIANAIVKQAEIEGIEHEEMHGKLQYI
                     ASKGIKSHIDGQPVLIGNYVLMQDEQIHISSEQNALIEEYKSHYNLLFLAYQNELIGM
                     FCIHTPLRKEAKTALDKLKAQGKKLILATGDTLVRTKELVKDLPFDQVYTDLKPDGKF
                     ELVEKLQKAGHTILMVGDGLNDSAALTLSDIGVVMNESADISKQMSDILLLDNRLDFF
                     QELDSLSSSLQTLIKKNIQDTVVVNSSLIGFGLFNWLSPSNLSILHNLTTLRIVLRSL
                     SIKNR"
     gene            complement(15727..16983)
                     /locus_tag="VVR63_000880"
     CDS             complement(15727..16983)
                     /locus_tag="VVR63_000880"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HEU6128911.1"
                     /translation="MHIFDELKERGLIFQTTDEEALRKALEEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKDTVDGWVKSIQ
                     GQLSRFLDFENGENKAVMVNNYDWFGSISFIDFLRDIGKYFTVNYMMSKESVKKRIET
                     GISYTEFAYQIMQGYDFFVLNQDHNVTLQIGGSDQWGNMTAGTELLRRKADKTGHVIT
                     VPLITDATGKKFGKSEGNAVWLNPEKTSPYEMYQFWMNVMDADAVRFLKIFTFLSLDE
                     IEDIRKQFEAAPHERLAQKVLAREVVTLVHGEEAYKEALNITEQLFAGNIKNLSVKEL
                     KQGLRGVPNYQVQADENNNIVELLVSSGIVNSKRQAREDVQNGAIYVNGDRIQELDYV
                     LSDADKLENELTVIRRGKKKYFVLTY"
     gene            17125..19590
                     /locus_tag="VVR63_000881"
     CDS             17125..19590
                     /locus_tag="VVR63_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEU6128912.1"
                     /translation="MQNQLNELKRKMLEFFQQKQKNKKSARPGKKGSSTKKSKTLDKS
                     AIFPAILLSIKALFNLLFVLGFLGGMLGAGIALGYGVALFDKVRVPQTEELVNQVKDI
                     SSISEITYSDGTVIASIESDLLRTSISSEQISENLKKAIIATEDEHFKEHKGVVPKAV
                     IRATLGKFVGLGSSSGGSTLTQQLIKQQVVGDAPTLARKAAEIVDALALERAMNKDEI
                     LTTYLNVAPFGRNNKGQNIAGARQAAEGIFGVDASQLTVPQAAFLAGLPQSPITYSPY
                     ENTGELKSDEDLEIGLRRAKAVLYSMYRTGALSKDEYSQYKDYDLKQDFLPSGTVTGI
                     SRDYLYFTTLAEAQERMYDYLAQRDNVSAKELKNEATQKFYRDLAAKEIENGGYKITT
                     TIDQKIHSAMQSAVADYGYLLDDGTGRVEVGNVLMDNQTGAILGFVGGRNYQENQNNH
                     AFDTKRSPASTTKPLLAYGIAIDQGLMGSETILSNYPTNFANGNPIMYANSKGTGMMT
                     LGEALNYSWNIPAYWTYRMLREKGVDVKGYMEKMGYEIPEYGIESLPMGGGIEVTVAQ
                     HTNGYQTLANNGVYHQKHVISKIEAADGRVVYEYQDKPVQVYSKATATIMQGLLREVL
                     SSRVTTTFKSNLTSLNPTLANADWIGKTGTTNQDENMWLMLSTPRLTLGGWIGHDDNH
                     SLSRRAGYSNNSNYMAHLVNAIQQASPSIWGNERFALDPSVVKSEVLKSTGQKPGKVS
                     VEGKEVEVTGSTVTSYWANKSGAPATSYRFAIGGSDADYQNAWSSIVGSLPTPSSSSS
                     SSSSSSDSSNSSTTRPSSSRARR"
     gene            19655..20566
                     /locus_tag="VVR63_000882"
     CDS             19655..20566
                     /locus_tag="VVR63_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEU6128913.1"
                     /translation="MNQYQKKIVNGKIYSLLSGLIWGICGILGEYFFTHYQVSSGWIT
                     SMRLTLAGSLVLIWSAIQLKSQVLDIWRDKKNYLPFLAYAILGIFSVQYFFYLCVEYS
                     NATTATILQFISPVFILFYNRLVYQKRASKSAVFYVLVAMLGVCLMATKGDLSQLSMT
                     PLALITGLLSAMGVMFNVILPQPFAKRYGFVPTVGWGMILAGLFSNVLSPVYQLSFTL
                     DIWSILICLIIAFFGTAFAFFISMKAVSLVSPLVVAVISASEPLSSALLSVLFLGLVV
                     DWSLLLAIALIILPMIFLSIEEAKESR"
     gene            20796..21494
                     /gene="dapD"
                     /locus_tag="VVR63_000883"
     CDS             20796..21494
                     /gene="dapD"
                     /locus_tag="VVR63_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HEU6128914.1"
                     /translation="MTATKMNAQEIIQFIANAEKKTSVKVTFEGQLATAVPSSVVKLG
                     NVLFGDWKDVAPLLEGLVENQDYVVEQDARNSAVPLLDKRAINARIEPGAIIRDQVEI
                     GDNAVIMMGAVINIGAEIGAGTMIDMGAILGGRAIVGKNSHVGAGAVLAGVIEPASAE
                     PVRVGDNVLIGANAVVIEGVQIGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDAQ
                     TQQKTALEDALRTL"
     gene            21562..22692
                     /locus_tag="VVR63_000884"
     CDS             21562..22692
                     /locus_tag="VVR63_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HEU6128915.1"
                     /translation="MLDLIQTRRDLHQIPEIGLEEFKTQAYLLDVIEKLTTGKDFVQI
                     RTWRTGILVYLQGSQPERTIGWRTDIDGLPIVEQTGLPFASQHQGRMHACGHDFHMTI
                     ALGCLERALEEQPKNNLLFLFQPAEENEAGGMLMYEDDAFGDWLPDQFYGLHVRPDLK
                     VGQIATNTHTLFAGTCEVKIRFKGKGGHAAFPHEANDALVAASYFVTQVQSVVSRNVN
                     PIEGAVVTFGVFQAGTTNNVITDTAFLHGTIRALTQDMSLLVQKRVKTVAEGVAAAFD
                     MEVEVELKQGGYLPVENNPALARELMDFFDEKDGIELIDIEPAMTGEDFGYLLSKVDG
                     VMFWLGIDSPYALHHPQMSPKEEVLAIGVAAVSSFLKKKAAE"
     gene            22704..23243
                     /locus_tag="VVR63_000885"
     CDS             22704..23243
                     /locus_tag="VVR63_000885"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HEU6128916.1"
                     /translation="MKSELRKQVLHEMKAISQEQKQAIDQALTERILQHPFYQEAKVI
                     ATYLSFSHEFQTRELIEQALKDGKKVLIPKTYPKGRMDFVVYDPQQLVKTAFALLEPQ
                     GDLEVVDASQIDLIHVPGLAFTTDGYRIGYGGGYYDRYLEHFSGHTLSTVHPCQIQDF
                     IPENHDIPVQEVLIDEGNL"
     gene            23227..23904
                     /locus_tag="VVR63_000886"
     CDS             23227..23904
                     /locus_tag="VVR63_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HEU6128917.1"
                     /translation="MKEIFDRRYPVTSFFLLVTALVFLLMLVTAGGNFDRADTLFRFG
                     AMYGPAIRLFPEQVWRLLSAIFVHIGWEHFIVNMLSLYYLGRQVEEIFGSKQFFFLYL
                     LSGMMGNLFVFVFSPKSLAAGASTSLYGLFAAIIVLRYATRNPYIQQLGQSYLTLFVV
                     NIIGSVLIPGISLAGHIGGAVGGAFLAVIFPVRGEKRMYNTSQRLGAVVLFVGLAILL
                     FYKGMGM"
     gene            complement(23976..24875)
                     /gene="galU"
                     /locus_tag="VVR63_000887"
     CDS             complement(23976..24875)
                     /gene="galU"
                     /locus_tag="VVR63_000887"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HEU6128918.1"
                     /translation="MTSKVRKAVIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVE
                     EALKSGIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDKTTDMRLHFI
                     RQTHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITDEKAVPLTKQLMDDYERTHAST
                     IAVMPVPHDEVSAYGVIAPQGEGKDGLYSVETFVEKPAPEDAPSDLAIIGRYLLTPEI
                     FQILENQAPGAGNEIQLTDAIDTLNKTQRVFAREFNGARYDVGDKFGFMKTSIDYALK
                     HPQVKDDLKNYLIQLGKELTEKE"
     gene            complement(24897..25913)
                     /locus_tag="VVR63_000888"
     CDS             complement(24897..25913)
                     /locus_tag="VVR63_000888"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HEU6128919.1"
                     /translation="MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINT
                     HHTNKHYFKDVVLDENIIAYTDLAETLKNVDAILFVVPTKVTRLVAQQVAQTLDHKVI
                     IMHASKGLEPDSHKRLSTILEEEIPEHLRSDIVVVSGPSHAEETIVRDLTLITAASKD
                     LQTAQYVQELFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAII
                     ARGLAEITRLGVALGASPLTYSGLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIE
                     ANMGMVIEGISTTRAAYELAQELGVYMPITQAIYQVIYHGTNIKDAIYDIMNNEFKAE
                     NEWS"
     gene            26125..26565
                     /locus_tag="VVR63_000889"
     CDS             26125..26565
                     /locus_tag="VVR63_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU6128920.1"
                     /translation="MREFGEKIKRLRLAKKISRSEFCGDESELSIRQLIRIENGESRP
                     TLTKLKYIAERLEVEDYKLMPSYIELDKEYLELKYFLMRTPTYEDETIAQKKESVFDK
                     IFEEYYDRLPEEERFIIPNYSYLALANYTVQKLPEKLVEILSFW"
     gene            complement(26688..27104)
                     /locus_tag="VVR63_000890"
     CDS             complement(26688..27104)
                     /locus_tag="VVR63_000890"
                     /inference="COORDINATES: protein motif:HMM:NF025080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU6128921.1"
                     /translation="MTNLSSVDSEELFQFYRERGNAENFIKERKAGFFGDKTDSSTMI
                     KNEVRMMMGCLAYNLYLFLKQLAGDEVKALTIKRFRRLFLHIAGKYVSTARRHILKFS
                     SLYAYSKQFQALFDTICQINLILPVPYRARGQGKTA"
     gene            complement(27172..27822)
                     /gene="phoU"
                     /locus_tag="VVR63_000891"
     CDS             complement(27172..27822)
                     /gene="phoU"
                     /locus_tag="VVR63_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEU6128922.1"
                     /translation="MRNQFDLELHELEQSFLGLGQLVLETASKALLALASKDKEMAEL
                     IINKDHAINQGQSAIELTCARLLALQQPQVSDLRFVISIMSSCSDLERMGDHMAGIAK
                     AVLQLKENQLAPDEEQLHQMGKLSLSMLADLLVAFPLHQASKAISIAQKDEQIDQYYY
                     ALSKEIIGLMKDQETSIPNGTQYLYIIGHLERFADYIANICERLVYLETGELVDLN"
     gene            complement(27837..28589)
                     /gene="pstB"
                     /locus_tag="VVR63_000892"
     CDS             complement(27837..28589)
                     /gene="pstB"
                     /locus_tag="VVR63_000892"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEU6128923.1"
                     /translation="MGTFSVRHLDLFYGDFQALKNISIQLPERQITALIGPSGCGKST
                     FLKTLNRMNDLVPSCHIEGQVLLDEQDIYSSKFNLNQLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGIRDKKQLDALVEKSLKGAAIWEEVKDDLKKSAMSLSGGQQQRLCIARA
                     LAVEPDILLMDEPTSALDPISTLKIEDLIQQLKKDYTIIIVTHNMQQASRISDKTAFF
                     LTGEICEFGDTVDVFTNPKDQRTEDYISGRFG"
     gene            complement(28591..29406)
                     /gene="pstA"
                     /locus_tag="VVR63_000893"
     CDS             complement(28591..29406)
                     /gene="pstA"
                     /locus_tag="VVR63_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEU6128924.1"
                     /translation="MSKYLLKLLVYCFSALTFGSLFLIIGFILIKGLPHLSLSLFSWT
                     YTSENISLMPAIISTVILVFGALLLALPIGIFAGFYLVEYTKKDSLCVKIMRLASDTL
                     SGIPSIVFGLFGMLFFVVFLGFQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDSMRQ
                     ASYGLGAGKLRTVFRIVLPVAMPGILAGVILAIGRIVGETAALMYTLGTSTNTPSSLM
                     SSGRSLALHMYMLSSEGLHVNEAYATGVILIITVLMINTLSSLLSRKLVKGAS"
     gene            complement(29399..30262)
                     /gene="pstC"
                     /locus_tag="VVR63_000894"
     CDS             complement(29399..30262)
                     /gene="pstC"
                     /locus_tag="VVR63_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEU6128925.1"
                     /translation="MIKQAFKEAVFRAIFFMSATVAVVAILLICFFIFSNGLPFMANY
                     GFARFLLGSDWSPTNIPASYGILPMIVGSLLITLGAIVIGVPTGILTSVFMVYYCPKP
                     VYGFLKSAINLMAAIPSIVYGFFGLQLLVPWIRSFLGNGMSVLTASLLLGIMILPTII
                     SLSESAIRTVPKTYYSGSLALGASHERSIFSVILPAARSGILSAVILGIGRAVGETMA
                     VILVAGNQPIIPSGLFSGTRTLTTNIVLEMAYASGQHREALIATSAVLFFLILLINAY
                     FAYLKGKSSYE"
     gene            complement(30380..31255)
                     /locus_tag="VVR63_000895"
     CDS             complement(30380..31255)
                     /locus_tag="VVR63_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate-binding protein"
                     /protein_id="HEU6128926.1"
                     /translation="MKFKKMLTLAAIGLSGFGLVACGNQSAASKQSASGTIEVISREN
                     GSGTRGAFTEITGILKKDGDKKIDNTAKTAVIQNSTEGVLSAVQGNANAIGYISLGSL
                     TKSVKALEIDGVKASRDTVLDGEYPLQRPFNIVWSSNLSKLGQDFISFIHSKQGQQVV
                     TDNKFIEAKTETTEYTSQHLSGKLSVVGSTSVSSLMEKLAEAYKKENPEVTIDITSNG
                     SSAGITAVKEKTADIGMVSRELTPEEGKSLTHDAIALDGIAVVVNNDNKASQVSMAEL
                     ADVFSGKLTTWDKIK"
     gene            complement(31422..32753)
                     /locus_tag="VVR63_000896"
     CDS             complement(31422..32753)
                     /locus_tag="VVR63_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HEU6128927.1"
                     /translation="MKRYLQFWLVNLSVSLILIAGMALTWISKGIGLFLLALSLGQGG
                     YWLFCLWKWEVAFETLHQPLLTSSEYFLEKGQEDLKSLAQYVSGLKTKVSQQDQQYKD
                     LAETMEVLLSHLTMGTFLVSAQGQMLLSSRSLPHYFPDVDGDISSLDDLKRMDIRNLV
                     HQAFDQKTRLKQEVSGFHEGDLILEVTAVPVFSPTQSVEAVLVLLYDLTTIRTYEKLN
                     LAFVSNASHELRTPVTSIKGFAETIKGMSAEEEALKDDFLDIIYKESLRLEHIVEHLL
                     TLSKAQQMPIQWTTLSLAEFVQDLTQSLQPQLKKKDLQLKVQVPDDVTLVSDSQLLSQ
                     ILLNLLSNAIRYTEQGGKIEVKTQKVNEGIKISVSDTGIGISQLEQDRIFERFYRVNK
                     GRSRQTGGTGLGLAIVKELSQLLGGQVTVTSQLGRGSCFTIFLPNQSFAQD"
     gene            complement(32754..33461)
                     /locus_tag="VVR63_000897"
     CDS             complement(32754..33461)
                     /locus_tag="VVR63_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU6128928.1"
                     /translation="MTKQVLLVDDEEHILKLLDYHLSKEGFSTQLVTNGRKALALAET
                     EPFDFILLDIMLPQLDGMEVCKRLRAKGVKTPIMMVSAKSDEFDKVLALELGADDYLT
                     KPFSPRELLARVKAVLRRTKGEQEGDDSDNIADDSWLFGTLKVYPERHEVYKANKLLS
                     LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKA
                     PQFIRTIRGYGYKFKEL"
     gene            complement(33545..34021)
                     /locus_tag="VVR63_000898"
     CDS             complement(33545..34021)
                     /locus_tag="VVR63_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000356607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEU6128929.1"
                     /translation="MDKEDLIRTLELAPHVEGGYFRQTKKASDTINLAGKGRALYTSI
                     YFLLEETNPSHFHRLTADEIWYFHAGSPLTVHMITADGHYEAVTLGLDISKGQQLHYC
                     VPKGTIWGSTVDKDYALVSCLVAPGFEFEDFELFERVDLLATYPEHKEMIERLTRY"
     gene            34028..34464
                     /locus_tag="VVR63_000899"
                     /pseudo
     CDS             34028..34464
                     /locus_tag="VVR63_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT        10194 a         6510 c         7370 g        10390 t
ORIGIN      
        1 attttcattg agtataaaaa gatcttggga aaagactcaa tttcagtaga aaaggaagta
       61 aatcttccca caataaaacg catagtatca agttttttca atacctgata gtatgcgttt
      121 ttgcttttaa cgactctttg cccagtctct tatttttcga taattttgtg ggcgatcaat
      181 tgacggtaac aaatttgttt attgttttta ttatcattaa taatctggag aatagtttca
      241 agggaaacac gaccaagctc taaactattg atatcgacat aggctgccaa gttgagcttg
      301 ggattaaccg agtcaaagct gagaacaggg acatccagct ggtgtttggc aatatagtta
      361 caaacacctt cagctaggag gctatcggtt gtgatgatag catcaatttg tggatcgtgc
      421 ttgaataatc gcttgctaaa tttatagccc ttttcttcca gaaactcgtc ggcaaagtag
      481 atgcgattgt tgtcagtggt aagtttgtaa tgtttaagcg cctgttcata gcctgttaaa
      541 cggtctttgg tcacgaagag ctttttactt cctccgataa aggcaatgcg tttgcagcct
      601 tttttgatga aatattcagt cgcatcaaaa ccagcttgaa cattgtcgtt gtcgacaagt
      661 gggatgaaag gagatagaga tttacctagg ataaggaagg ggaactgttc ttctgcgacg
      721 agttttacga gagggtcttc ttcttgggca tagagaaaga ttagcccatc tacacgcttg
      781 ccgtagacca tttgtgaaat agcgttgaga cgctccttct catctttccc tgttgctatc
      841 tgaatggcat agtggttttc agatgcgact tgagagatgc cacgtagaac cgatggaaag
      901 aaaggattct ggtagaaggc gtctgagtca tcaggaagaa ctaatccgat aacctgagta
      961 tagctgctta ccaagctacg agcgttgagg tttgggtggt agttgagttc cttcatagcc
     1021 ttgcgaacgc gtttttttgt ttcgtcgcta atggttgatt tattttgaat aacacgggtt
     1081 acggttgaag gcgaaacacc agcagccttg gccacgtctt taatcgtaac gggcataaaa
     1141 atctcctatt tatggtaatt tggatcacgg aaatgtgttt tataaaagat agtgaccaga
     1201 tacagaacaa aaagaatatt ttgtacagta atcagggttg tcatattttg gccaaataat
     1261 cccaaaataa gtgtaatcag agtcggcaat cctaaacagt tcaagataaa gtgatagcac
     1321 tctttaaagg ttctaaatga aaagaggcgt gatttcttag tgatataaag gagaagacta
     1381 gctcctagag agacgataaa gaaattcaaa ccaaagagga agctcgcacc gagaactagg
     1441 aagaggctga tatagacacg attttgttgg taccagtctt tagaaattgc ttgggtcaag
     1501 ctgtctttgc ttttgaaact ctcagtctga atggctcggt aagagatgcg ggtcagttcc
     1561 ttgctttcct tgctgatgac tagctcattt gtatcgaaat gcagttgcaa gttcttaggt
     1621 aattccttga tttgacttgg accaatcaca acagaagagg cttgactaac tgttccagta
     1681 taagttaatg tgccatcgac aattgtagca tgttcagaga gatcctggac aacctcattt
     1741 gtcagaggtt catagacatt atcgataaaa gtttctagcg gataggtctc ctgggagctg
     1801 ttttggatag caatgggtac catagacaag ctgataagga agatactggt aaagagaagt
     1861 tgaaaccagt tgagcccgaa acgtttggac aggggcttac gaaaccccaa aatacttgaa
     1921 aaaaaggaaa atggatatgg aagcataggt atctttctaa aaggtgtttt ctatataagt
     1981 attattatat agagaaatgc gctttatttc aagtctagga gaaaaattgc ttgctacaag
     2041 gatattattt acagtgacaa ttgctaataa tcaatgaaaa tcaaagtgca aactagccac
     2101 aggttgctca aagcacaact ttgaggttgg agataaagct gacgtggttt gaagagattt
     2161 tcgaagagta taaaatgaaa aagggtggcg gggataaatt atcccttgtc gccaccactt
     2221 gtaagtcctg aaacaaagtt cttttgtagg aagaagaaga gaatacagat tggaagggcg
     2281 atgaggatag cacctgctga gaagtaggca atcttcaagt ttttcgcatt gttaacgaag
     2341 gtttggagac ctacggcaac agtaaagtat tctttctcac gaagcaagaa actagagagg
     2401 atgtagtccc cgaaaggtcc catgaaggcc cagagagctt gtacggcaac cattgggcga
     2461 acaagtggaa gaacaatttg ccagaagcgg cggaagtgtc ctgcaccgtc tagttttgca
     2521 gattcgtcta aagacattgg cactgtatcg aagtagcctt tcatgagcca agcattcatc
     2581 gggataccac caccaacgta gaggaagatg aggaaccagt tgtggttaag ggcgttcaac
     2641 ataagcgcca taacgaagaa ggctgtcaaa gcggccatag ttggcaccat ttggatgatc
     2701 aagaagaaga ccaaactttg tttacgagcc aagaagttgt aacggctgta agcataacca
     2761 gcaagtacga tgatacttgt ttgaacagcc atggtaatta aggcgataat caaagtgttg
     2821 aggtaccaag taccgtacaa ggtttcagtg aagaggcctt taaagttatc aaaattgagg
     2881 tcgatattag tatctagttt aaaggctgag acgttacctg ctttaaaggc tgacataatg
     2941 gtaatcaaca gtggatagat aattacaatt gatagaccaa tcaggtaaag gtaagtaagg
     3001 ctttgagtca gtctacgttt gagtttaatt gagttattca tcttagacgt cctccatatc
     3061 aaatgcgtgt agtttcttga atgcgatcat agagattgag atgacaatga tagagataat
     3121 caaggtaaca gctgccgcca ttgagtattg aggagatgta cctgttgtca aacggtagat
     3181 ccatgagatc aagatatcgg ttgaaccagc tccacctccg acactaccag gtcctccacc
     3241 attgaagagg tacatgatag agaagttgtt aaagttgaag gtgtattggc taatcaaagt
     3301 aggtgccgca acagccaaaa tcattgggaa agtgatgttg cggaattttt gccaagcgtt
     3361 ggcaccgtca atataagctg cttcgtaaag gtcgttagga atagattgca agatacccaa
     3421 ggtcagaacg tagatgtatg ggaatccgag ccaaccttgc atcataatca aggcaatctt
     3481 agtccaagtt gggtctgttt tccaaggaat aagagctcca tcaaggaaag gaaggaattt
     3541 agccaagatt ggcaatactt gagtgttgat agcaccgaca ctatcgttaa acatgtttga
     3601 gaatgtcaag atagtgatga aggctgggac agcccaagga agaaggaaaa taacaccaaa
     3661 gatacgtttt cctttgataa atggttggtt ggcaatgata gctgtgaaga taccaattac
     3721 gatttgtaaa gtagaagctg ccaaagccca aatgatagtc caagaaagaa cagaaccaaa
     3781 ggcagaacgg aaggtactca agctccaaat gtttgtaaag ttggtcaaac caacccagtc
     3841 caacaacttg tttggtggca agtgttggaa gtcgtagttg gtaaaggcga tcatcaaggt
     3901 tacgataact gggaagataa tcgcgaaggt catggcaaca taagatggaa tgatcaagag
     3961 gtaagggaag ccattttcat aaatcccttt gatcatgtct ttgagtgtgc gtggaactgg
     4021 aattccattg ttaatgcgtt ttgcaatcgt atgtgcatct ttgatatttg agaaataaaa
     4081 gagtacataa acgattacaa agattagatg gaaggcacca cgaatcagca taaagaggga
     4141 attatcacga cctggtttgt caccaagagt gatgaggttg ctcaattcag gggttgcaag
     4201 tgctaggaag taaaggacaa atacgatggt tacaccaagg aagataaaac ctttggcttt
     4261 ttgtttattg taaatctgtc ctaacccagg aatgatagac agcagggctg ctttactagg
     4321 ttgttgcttt tccatattaa ctcctttcat aggatactac ttttttataa gaaagctaaa
     4381 ttatttgtgt ctctattgat aaattcaaag ggggatttga tttccacccc ccttgaacaa
     4441 attttttatt caccaaattt ttgtttgatt gtttctttga tcaatgttac agcatcgtta
     4501 gcagctgttt tagcatcttt ttgaccactt acagcatcaa agagcatatt tttcgctgga
     4561 tcccaaactg cagacatttg agagatgttt ggcagtggtt gagtgttctt gaactgtttg
     4621 ataacagctg ttgtcaactc atcgttttta ccttcagcgt atgaacgagc ctcagtatta
     4681 gctgggattt cgttagtctt atcatataat actttttgtt gttcagttgc aacaaggaag
     4741 tctacaaatt tttgagaagc ttcaaggttc ttaacggctt gaggaatgac ccaagcttta
     4801 ccaccaccga atgcagcata ttcttttcca tttggaagag ttgggatagt tgcaactccg
     4861 tagtttactt tagcatcttt aaaggcttga gctttccaag gtccgtcgat gatagcagct
     4921 gttttacctt cttggaattg agtttggatt aagtttccag caccttctgt atcttgcata
     4981 cctttaggcc atttttcgta ccaagattta gcgtagttga tacctacgat agaaccgtcg
     5041 tttgcaagac cgatgtcttt agcgtcttta ccgttttggc caaagacgta agcaccgtta
     5101 ccggcaagaa gtccatatgt atagtagaag tttgtccagt cagctaggaa ggcagtagtt
     5161 ttaccatctt caccagcgaa tgcgtatttg ctatctttag caaggttttc caagtcagca
     5221 aatgtttttg gagcatcttt caccaagtct ttgttgtagt acataacaag tgactcgata
     5281 acggcaggag caccgtaaac tttaccatta gcagctgtta caagagattt agttgtgtcg
     5341 tctgttttag caccatcgct caatttcact tctgaaagtt gtccgtcaga accaaggcta
     5401 cctacacggt cgtatggagc catcataaca tcagggacat taccagattg gttgtcaaga
     5461 gaaagtttat caagacctcc tagagcatca ccagttttaa gagtgacttt tactccagct
     5521 tctttttcat aagctttagc aacctcttca atatagctct tatatccctc gtctacatat
     5581 acagtgagtt ctttgacttc agatgaacca gaatcagcag gcttatcagc agttttgctt
     5641 ccgcaagcta ccaaaagcaa gctagcaagt gtaacagttc caagcaccgc agtgctcttc
     5701 ataaatttag atgacatagt gtattcctcc caaagaatag caagttttat tgataaggaa
     5761 acgcaaacgt tttcttttat gagcttagta tagcacaaat agaaaacggt tgcaagtatt
     5821 ttttgtaaaa attttaaaaa atttttaagc ttgatttgat agcataattt tgcattttaa
     5881 tagaagaaaa gtatgaaata gataagaata cagtattttt aataaaaata tatggaatct
     5941 gtctaaagag ggaaaccagg aggggctacc tccctggttc taatccctat ctattttcta
     6001 tggacgtttg tgctttgtta catataaatt caagctccct aaggaggttt tgtactttgt
     6061 agactgtctc gtgagagtca aaccttagga ttagatagtt ttaagttatc tttgctaaaa
     6121 tgagttagtc tccttaaaaa taatcaaaaa agttttttaa aaacgcttgc aattatgctt
     6181 gaaaaggagt atacttataa gtaacgcaaa cgtttgcgtc tgcaaaatac gcaacgttcc
     6241 attattttaa cacacgaggt gctattatga aaaaacgtca aagtggtgtg ttgatgcaca
     6301 tctcttctct tccaggagct tacggaatcg gatcatttgg tcaaagtgct tacgacttcg
     6361 ttgatttctt ggtccgtaca aaacaacgtt actggcaaat ccttccatta ggagcaacta
     6421 gttacgggga ttctccttac caatctttct cagccttcgc aggaaacact cattttatcg
     6481 atttagatat cttggtggag caaggtttgt tggaagcaag tgatcttgaa ggagttgact
     6541 ttggtagcga tgcgtctgaa gttgactatg ctaaaatcta ctatgcacgt cgtcctcttt
     6601 tagaaaaagc ggtgaaacgt ttctttgaag tcggagatgt taaagatttt gagaaatttg
     6661 ctcaagacaa ccaatcatgg cttgagctct ttgctgagta tatggctatc aaagagtatt
     6721 ttgacaatct tgcttggact gaatggccag atgcagatgc tcgtgctcgt aaagcttcag
     6781 cacttgaaag ctatcgtgag caattggcag acaagttggt ttaccaccgt gtgactcaat
     6841 acttcttctt ccaacaatgg ttgaaattga aagcttacgc taacgacaac cacatcgaaa
     6901 tcgttgggga catgccaatc tacgtagcgg aagattcaag tgatatgtgg gcaaatccac
     6961 atctcttcaa aacagatgtc aatggtaagg ctacttgtat cgcaggatgc ccaccagatg
     7021 agttttctgt aactggtcag ctttggggta acccaatcta tgactgggaa gcaatggaca
     7081 aagacggcta caaatggtgg attgaacgct tgcgtgaaag cttcaaaatc tacgatatcg
     7141 ttcgtatcga ccacttccgt ggcttcgaat cttactggga aatccctgct ggttccgata
     7201 cagcagcacc tggtgagtgg gtgaaaggtc caggctacaa gctttttgca gccgttaagg
     7261 aagaacttgg tgagctaaac atcatcgcag aagaccttgg cttcatgaca gatgaagtga
     7321 tcgaattgcg tgaacgtact ggcttcccag gaatgaagat tcttcaattt gccttcaacc
     7381 cagaagacga aagcattgat agcccacact tggcacctgc taactcagtt atgtacacag
     7441 gaacacacga taacaatacg gttcttggtt ggtaccgtaa tgagattgat gatgcgactc
     7501 gtgagtacat ggctcgttac acgaaccgta aagaatacga aacagtggta cacgctatgc
     7561 ttcgtacagt attttcatca gttagcttta tggcaattgc aactatgcaa gatttactag
     7621 aattggatga ggcagctcgt atgaacttcc catctaccct tggtggaaac tggtcttggc
     7681 gtatgactga agatcaattg acaccagctg tcgaggaagg tttgcttgac ttgacaacaa
     7741 tttatcgccg aattaatgaa aatttggtag atttaaagaa ataagacaat aatcaggaga
     7801 caactaaaca tgttatcact acaagaattt gtacaaaatc gttacaataa aaccattgca
     7861 gaatgtagca atgaagagct ttaccttgct cttcttaact acagcaagct tgcaagcagc
     7921 caaaaaccag tcaacactgg taagaaaaaa gtttactaca tctcagctga gttcttgatt
     7981 ggtaaactct tgtcaaacaa cttgattaac cttggtcttt acgacgatgt taaaaaagaa
     8041 cttgcagctg caggtaaaga cttgatcgaa gttgaagaag ttgaattgga accatctctt
     8101 ggtaatggtg gtttgggacg tttggctgcc tgctttatcg actcaattgc tactcttggt
     8161 ttgaatggtg acggtgttgg tcttaactac cactttggtc ttttccaaca agttcttaaa
     8221 aacaaccaac aagaaacaat tccaaatgca tggttgacag agcaaaactg gttggttcgc
     8281 tcaagccgta gctaccaagt accatttgca gactttactt tgacatcaac tctttacgat
     8341 attgatgtta ctggttatga aacagcgact aaaaaccgct tgcgtttgtt tgacttggat
     8401 tcagttgatt cttctattat taaagatggt atcaactttg acaagacaga tatcgctcgc
     8461 aacttaactc tcttccttta cccagatgat agtgaccgtc aaggtgaatt gctccgtatc
     8521 ttccaacaat acttcatggt ttcaaacggt gcgcaattga tcatcgacga agcaatcgaa
     8581 aaaggaagca acttgcatga ccttgctgac tacgcagttg tccaaatcaa cgatactcac
     8641 ccatcaatgg tgattcctga attgattcgt cttttgactg cacgtggtat cgatcttgac
     8701 gaagcaatct caattgttcg tagcatgact gcctacacta accacacaat ccttgctgaa
     8761 gcgcttgaaa aatggcctct tgaattcttg caagaagtgg ttcctcactt ggtaccaatc
     8821 atcgaagaat tggaccgtcg tgtgaaggca gagtacaaag atccagctgt tcaaatcatc
     8881 gatgagagcg gacgtgttca catggctcac atggatatcc actacggata cagtgttaac
     8941 ggggttgcag cactccatac tgaaatcttg aaaaattctg agttgaaagc cttctacgac
     9001 ctttacccag aaaagttcaa caacaaaaca aacggtatca ctttccgtcg ttggcttatg
     9061 catgctaacc caagattgtc tcactacttg gatgagattc ttggagatgg ttggcaccat
     9121 gaagcagatg agcttgaaaa actgttgtct tatgaagaca aagcagctgt caaagaaaaa
     9181 ttggaaagca tcaaggctca caacaaacgt aaattggctc gtcacttgaa agaacaccaa
     9241 ggtgtggaaa tcaatccaaa ttctatcttt gatatccaaa tcaaacgtct tcacgagtac
     9301 aaacgccaac aaatgaacgc tttgtacgtg atccacaaat accttgacat caaagctggt
     9361 aacatccctg ctcgtccaat cacaatcttc tttggtggta aagcagctcc agcctacaca
     9421 atcgctcaag acattatcca tttaatcctt tgcatgtcag aagttattgc taacgatcca
     9481 gcagtagctc cacacttgca agtagttatg gttgaaaact acaacgttac tgcagcaagt
     9541 ttccttatcc cagcatgtga tatctcagaa caaatttcac ttgcttctaa agaagcttca
     9601 ggtactggta acatgaaatt catgttgaac ggagctttga cacttggtac tatggacggt
     9661 gctaacgtgg aaatcgctga gttggttgga gaagaaaaca tctacatctt cggtgaagat
     9721 tcagaaactg ttatcgacct ttacgcaaaa gcagcttaca aatcaagcga attctacgct
     9781 cgtgaagcta tcaaaccatt ggttgacttc atcgttagtg atgcagttct tgcagctgga
     9841 aacaaagagc gcttggaacg tctttacaat gaattgatca acaaagactg gttcatgact
     9901 cttcttgact tggaagacta catcaaagtc aaagagcaaa tgcttgctga ctacgaagac
     9961 cgtgacgcat ggttggataa agtcatcgtt aacatttcta aagcaggatt cttctcatct
    10021 gaccgtacaa tcgctcagta taatgaagac atctggcact tgaactaata ctcttcgaaa
    10081 atctcttcaa accacgtcag ctttatctgc aacctcaaag cggtgctttg agcaacctgc
    10141 ggctagcttc ctagtttgct ctttgatttt cattgagtat aagatacaaa tttatactaa
    10201 tacattttgt aaaaaagcga gtttcgattg aaattcgctt ttttaaatgc tgtggatttg
    10261 ggtcaatctt gtctaaaaat agggaaatcc tagatacagt gaaggcttta aatgctggtt
    10321 tttactgtct tcagccttat attttttcgt agttggttac ctcatatctc ttgtattcgc
    10381 ttacataaag tattataata taattgtagg aaagaaggtg tttttatgat atacacactt
    10441 aaattggtgt tgtttattac ctttcttgta ataagcttgt tacctgataa gatttttgga
    10501 aaaaataaaa aaatttggaa aatagttttt gcaatattga cggcagtggc agcattgtca
    10561 tttatgtact aagttatttt aagaatgtag ggaaataaac cctacatttt tttagttttt
    10621 tctgttttct aaattctatt tatccaagag cttcaacatt tcttgcttct tcgcttcaag
    10681 ttctgcacgc ttttcttcga tttcggcatg ttttttctcg agttcagaac aacttgcatc
    10741 attgctaaat tcttttcgcc atcaggagat agggtgagtc tacatgtcta ttactcaccc
    10801 aaagcagtcc tacaaagcag gaattttctg ttactttttt ggaaatagta acgtttatac
    10861 agctttgaca cttcgtatca aagcgccaaa cacactccga gggatttaca gaaagcagaa
    10921 aaggaatgat ctggtataag atcattcctt ttctctcttt ttctttaagt aattatatac
    10981 aatgtacgac gaagtcgtca ttgcaatgct gatccaccac ctaaagggaa ctttaaacaa
    11041 cattgataag ataaagaata taaacaacga aaatacgtta tacccaatta attttattgt
    11101 atatctcatg attaaaagtt aatccttccg ttgttaggaa tggcatcatt tttatcccat
    11161 aattgtgcta aataagtccc cggtgataat aaattcatag cgaattctaa agcaacatca
    11221 tttacaaacc aactacctag atatctagaa attgctgaac gaatagcact ttttgctgca
    11281 tgttttcctt ttactttaat tagatttgca aggcctgcag tagttcctcc taatgctaaa
    11341 gctattgcag tatctaatag agcacccatt tgattaactg taataccttg ccaagctgct
    11401 ctaaatggag agtatgtagg tgggattgta taatcgcctt gtaattgtcg gttaattact
    11461 tctttgatcc attgttgtga gacgtctgga tgaaaagatt ggatttcgtt tgcaagtgta
    11521 ttgatttgtt cttctgttag agaagtgaca ggttgaagtt ccatatttgt ttcaatttgt
    11581 gatacttgtt cagaagcgta tacagctgaa acacttggaa tcgctgatac aattaacaca
    11641 attgacgtca aaaaaaccga aataaatttc attaatttgt tcatgagctt ttctcctttt
    11701 tatttgtatc tgcttacatt ttatcatata ctgttattat agtcaaaaaa atatgctatt
    11761 atgttaaaaa aatatttttc aaaatataaa tggacggatt tattttggat tttatttgtt
    11821 attttgacct gcctctatat tggtaaccat gatttgttta ctctcaatca tcaagaattc
    11881 tcttttcgtg gtagcgtttg gggtctggta ctggccttat atcacttatt gttcattgat
    11941 aagtttgtaa tttcgaatcg aaaataaaga ttagaactat gattgactgg ctacttttaa
    12001 tattgatttt ggaggaagat tttgtctcta ttatttatta ttttaaattt atctattttg
    12061 tacaagattt attctttgag acgggagaaa tcgaaatact tgatttatac ggcctatatc
    12121 atatttgggg taaatgtagt atatggtatt caatggttat taagagaact gatttcaact
    12181 atttcccctt aatgtgtatg gaaactataa caaaacgcat aagattaagg tttgtgtacc
    12241 tgttcttatg cgtttttata atattgaaga ttttcggtaa gttttatacc tttgggaagt
    12301 ctagtttaga atgctttccc aaccaaaatc tctgcttcga tggtaatctc tgtcagttgg
    12361 ctccagtcaa tcttgctctg gtcaacgtga aagaggagag gagtcatact gagtagggct
    12421 tggagttgtt ctgctgtgat agtcttagtc agagaggcag tttgactaga taggatggta
    12481 aagtgttcct ggaaatgctc cttgatatct tggttagaat actccttgtt tgtcagctgg
    12541 tcctgtactc tttgacggat ttctttgagg tgattttcag ttgggataac ctttatcaag
    12601 ataccgtctt tggataaaac gcgacgaaat tctccatagt tggcaggtga gaagatatca
    12661 agcagaatat ccatgttagc gtcttttata ggaagtcgtg ccaagtcgcc aacaaaccaa
    12721 ttgactgccc agttgggttc acttttagca gcgatttgga ctgaatcttt ggagatgtca
    12781 aaggcataga aagttttttc agagtgactt tcttgtagtt tgcgagaata gaatccttca
    12841 ccacaaccga tatccaaaat tgttgtggta gtttttgagc ttgcaagcaa gtcagataca
    12901 gcatctaaga tagcttggta aaagccggct tctaggattt gttgacggtt ttgaaaattt
    12961 tccttgttat agttagcaga ttgcttgatt tgaggtgcta gattgacata gccaaatttc
    13021 gccaagtcaa aagaatgacg gttgcagcac ttgaaattag tctctaacag agtcagattt
    13081 tcttgacaga taggacaggc aaaggcagtc gcagaagcaa aacgctgaag tttgggcttg
    13141 agatttgtat tcatagttta agtgtatcaa aagaggcaaa tgaaagcaac tttaggaata
    13201 agtagatggg agattcagta gaaataaaac taattctcca atttatagaa tgaaattgct
    13261 tttatatcta aattgctata taataatgat aaggaggaaa taagtatgtt aaaagaagta
    13321 ttaaccgttg caaaagttgc gaaaaaatct tcattatttt tgggtggtgt cgcatttggt
    13381 acccttggtt tgaaaatctt agcaagtaag gaagctaaaa aaggttattc taaagctttg
    13441 gctaaggctt acaagttgaa agacgagcta gatgcatctg tttctgttgt gaagcaacat
    13501 ggagacgatg tcttgcaaga tgccaaatat ttgtacgagc aagagaaaaa agaagagcaa
    13561 ttagatagcc ttataggtga ataatatgtc ttttaaagtg ctacatagag gataccaaca
    13621 tatccgacta tcatcttctt tttcacttac cttggatatt caagactatc ttcgttcctt
    13681 ggcgagagat gaaaagggga ttgagtctat ccagttttac atggatcaac agcactttac
    13741 tctacgcata aaagaaggct tttctgtatt agataatgca gaagcctttt taaaaagaat
    13801 tgataaaggg aaagtttctg agttgatgac tcttcccatt cgtagagaag agagtgctta
    13861 ttctattgtt tcaggtgcag cggttaagcg tgtacttttt cgtagttttg tgccgtatcc
    13921 tattcgctat atatggactt gttatcaggc tttgggttat attagagaag cctatcaaac
    13981 actagcgcgt aaggaactaa cgatggaagt cttggactgt tcggctattt tattgtcttt
    14041 gtttatgaac caatccaaga cagctagcaa tatcatgttt atgcttgatt tggggaatca
    14101 tttagatcag tggtccttga aaaaaactgc aacagattta gaacagagtc ttcttgcaaa
    14161 agagagcgat gtattcctag tacagggcga tacggttgtt agtatcaaga gttccgatgt
    14221 tcaaatagga gatgtcttga tcttatctca aggaaatgaa attctgtttg atggacaagt
    14281 agtttcaggt ttaggtatgg tcaacgaaag ttccttgaca ggagagagtt ttccagttga
    14341 aaaaagagag tctgatttgg tttgtgcaaa tacagtatta gaaactggag agttacgcat
    14401 tcgtgtaaca gataatcaga tgaacagccg tattttacag ctgattgagt tgatgaagaa
    14461 atctgaagaa aacaagaaaa cgaaacaacg ctatttcatc aagatggcgg ataaagtcgt
    14521 caaatataat ttcttggggg ctgggctgac ttacctattg acaggttctt tttctaaggc
    14581 tatttctttc ctattggtcg atttctcctg cgctttgaaa atctctactc ctgtagctta
    14641 tttgacagtt atcaaggaag ggttgaaccg tgaaatggtg attaaggatg gagatgttct
    14701 ggagaaatat ctggaagttg atactttctt gtttgataag acaggaacaa tcacaactag
    14761 ttatcctata gttgaaaagg tgttaccttt tggagactat agtgaggaag atattctcag
    14821 aatcagtgcc tgtcttgagg aacacattta tcatcctatt gctaatgcca tcgtcaagca
    14881 agctgagata gagggaattg aacatgagga aatgcatggg aaactccaat atatcgcaag
    14941 caaggggatc aaatctcata tagatggcca accagttctt attgggaatt atgtcttgat
    15001 gcaggatgag cagattcata tcagttcaga acaaaatgct ttaattgaag agtacaagag
    15061 tcactacaat ctcttattct tggcttatca aaatgaattg attggaatgt tctgcattca
    15121 tactcctttg agaaaagaag caaaaacagc cttggataaa cttaaggcac aggggaaaaa
    15181 attgattctg gcaacagggg acaccttggt taggacaaag gaattagtca aagatttgcc
    15241 ctttgatcag gtctatacag acttgaaacc tgatgggaaa tttgagttag tagagaaact
    15301 gcagaaagca ggtcacacta ttttgatggt tggagatgga ttgaatgact cagcggcttt
    15361 aactctatca gatatcggtg tggtgatgaa tgagagtgca gatatttcta agcagatgag
    15421 tgatatctta ttgttagata atcgtttgga tttcttccaa gagttggatt cgttatcatc
    15481 atctttgcaa acactcatca agaaaaatat tcaagatacc gttgtcgtaa atagtagttt
    15541 gattggcttc ggcttattta attggctcag tccttcaaat ctctctatct tacataatct
    15601 aacaaccttg cgcattgtcc tgcgtagcct gtctattaaa aatagataga tgagagttat
    15661 taacagcaaa aaggagttac ctttctcgag gttaactcct ttgtttatag ataaatgttg
    15721 aatagtttag taagtcaata caaagtattt tttcttccca cgacggataa cagtcagttc
    15781 attctctaac ttatcagcgt cactcaagac atagtcaagc tcttggatgc ggtcgccgtt
    15841 tacgtagatg gctccgtttt ggacgtcttc acgggcttgg cgttttgagt taactatacc
    15901 agatgagacg agcagttcca cgatattgtt gttttcgtct gcctgtactt ggtagtttgg
    15961 cacaccacga agtccttgtt tgagctcttt gacagaaagg tttttgatgt ttcctgcaaa
    16021 gagttgctca gtgatgttaa gtgcttcttt gtaggcttct tctccgtgaa caagtgtaac
    16081 aacttcacga gccaagactt tttgagccaa gcgttcgtgt ggcgctgctt caaattgttt
    16141 acgaatatct tcaatctcat caagtgacaa gaaagtaaag attttcaaga agcgaacagc
    16201 gtcagcgtcc atcacgttca tccagaattg gtacatttcg tatggagaag tcttttcggg
    16261 attgagccag acggcatttc cttctgattt accaaatttc ttaccagttg catctgtgat
    16321 tagtggaaca gtgataacgt gaccagtctt gtccgcctta cgacgaagca attcggtacc
    16381 agctgtcata tttccccact ggtcagaacc accgatttga agagtgacat tatggtcttg
    16441 gttaaggacg aagaagtcat acccttgcat gatttggtaa gcgaactcag tgtaagaaat
    16501 tcctgtttcg atccgttttt taacagattc cttactcatc atgtagttga ccgtgaagta
    16561 ttttccaata tcacggagga agtcaatgaa gctgatgctg ccaaaccagt cgtagttgtt
    16621 gaccatgaca gccttgtttt cgccattttc aaagtcaaga aaacgagaaa gttgtccttg
    16681 gatagacttg acccagccat ctactgtgtc ttttgtttgg agactacgtt cagcatcttt
    16741 gaaggacgga tctccgatga gacctgtagc accgccaacg agcgcataag gtttgtgacc
    16801 tgctagttgc aagcgacgac ttgtcaagat tgcgacaagg tggcctaggt gaaggctgtc
    16861 agcagttgga tcgtagccag tataataaga aacttgacct tcttctaggg ctttacgcaa
    16921 agcttcttca tcagtcgttt gaaatatcaa accacgctct tttagctcat caaaaatgtg
    16981 catgtgtttt ttctcctttt taaaattatt gtttctacct attgtatcac aaacttgggc
    17041 aatagcctag cagaataggg aagaaagtgg ctattttatt gaaaatttcc cttttgtggt
    17101 ataatagata aagtgaggaa atccatgcaa aatcaattaa atgaattaaa acgaaaaatg
    17161 ctggaatttt tccagcaaaa acaaaaaaat aaaaaatcag ctagacctgg caagaaaggt
    17221 tcaagtacca aaaaatctaa aaccttagat aagtcagcca ttttcccagc tattttactg
    17281 agtataaaag ccttatttaa cttactcttt gtactcggtt ttctaggagg aatgttggga
    17341 gctgggattg ctttggggta cggagtggcc ttatttgaca aggttcgggt gcctcagaca
    17401 gaagaattgg tgaatcaggt caaggacatc tcttctattt cagagattac ctattcggac
    17461 gggacggtga ttgcttccat agagagtgat ttgttgcgca cttctatctc atctgagcaa
    17521 atttcggaaa atctgaagaa ggctatcatt gcgacagaag atgaacactt taaagaacat
    17581 aagggtgtag tacccaaggc ggtgattcgt gcgaccttgg ggaaatttgt aggtttgggt
    17641 tcctctagtg ggggttcaac cttgacccag caactaatta aacagcaggt ggttggggat
    17701 gcgccgacct tggctcgtaa ggcggcagag attgtggatg ctcttgcctt ggaacgcgcc
    17761 atgaataaag atgagatttt aacgacctat ctcaatgtgg ctccctttgg ccgaaataat
    17821 aagggacaga atattgcagg ggctcggcaa gcagctgagg gaattttcgg tgtagatgcc
    17881 agtcagttga ctgttcctca agcagcattt ttagcaggac ttccacagag tcccattact
    17941 tactctcctt atgaaaatac tggggagttg aagagtgatg aagacctaga aattggctta
    18001 agacgggcta aggcagttct ttacagtatg tatcgtacag gtgcattaag caaagacgag
    18061 tattctcagt acaaggatta tgaccttaaa caggactttt taccatcggg cacggttaca
    18121 ggaatttcac gagactattt atactttaca actttggcag aagctcaaga acgtatgtat
    18181 gactatctag ctcagagaga caatgtctcc gctaaggagt tgaaaaatga ggcaactcag
    18241 aagttttatc gagatttggc agccaaggaa attgaaaatg gtggttataa gattactact
    18301 accatagatc agaaaattca ttctgccatg caaagtgcgg ttgctgatta tggctatctt
    18361 ttagacgatg gaacaggtcg tgtagaagta gggaatgtct tgatggacaa ccaaacaggt
    18421 gctattctag gctttgtagg tggtcgtaat tatcaagaaa atcaaaataa tcatgccttt
    18481 gataccaaac gttcgccagc ttctactacc aagcccttgc tggcctacgg tattgctatt
    18541 gaccagggct tgatgggaag tgaaacgatt ctatctaact atccaacaaa ctttgctaat
    18601 ggcaatccga ttatgtatgc taatagcaag ggaacaggaa tgatgacctt gggagaagct
    18661 ctgaactatt catggaatat ccctgcttac tggacctatc gtatgctccg tgaaaagggt
    18721 gttgatgtca agggttatat ggaaaagatg ggttacgaga ttcctgagta cggtattgag
    18781 agcttgccaa tgggtggtgg tattgaagtc acagttgccc agcataccaa tggctatcag
    18841 accttagcta ataatggagt ttatcatcag aagcatgtga tttcaaagat tgaagcagca
    18901 gatggtagag tggtgtatga gtatcaggat aaaccggttc aagtctattc aaaagctact
    18961 gcgacgatta tgcagggatt gctacgagaa gttctatcct ctcgtgtgac aacaaccttc
    19021 aagtctaacc tgacttcttt aaatcctact ctggctaatg cagattggat tgggaagact
    19081 ggtacaacca accaagacga aaatatgtgg ctcatgcttt cgacacctag attaacccta
    19141 ggtggctgga ttgggcatga tgataatcat tcattgtcac gtagagcagg ttattctaat
    19201 aactctaatt acatggctca tctggtaaat gcgattcagc aagcttcccc aagcatttgg
    19261 gggaacgagc gctttgcttt agatcctagt gtagtgaaat cggaagtctt gaaatcaaca
    19321 ggtcaaaaac cagggaaggt ttctgttgaa ggaaaagagg tagaagtcac aggttcgact
    19381 gttaccagct attgggctaa taagtcagga gcgccagcga caagttatcg ctttgctatt
    19441 ggcggaagtg atgcggatta tcagaatgct tggtctagta ttgtggggag tctaccaact
    19501 ccatccagct ccagcagttc aagtagtagt tctagcgata gcagtaactc aagtactaca
    19561 cgaccttctt cttcaagggc gagacgataa ttctctaaat gaagtggcca atcaatggat
    19621 tgccactttt ttcttttcgt gttacaataa gggtatgaat cagtatcaga aaaagattgt
    19681 taacggaaaa atttattcgc tcctatccgg cttaatatgg ggaatctgtg gaattttagg
    19741 agagtacttc tttactcatt atcaggtgtc ttcgggctgg attacctcta tgcgtttgac
    19801 actggcaggg agtcttgtac tcatttggtc tgcaatacaa ttaaaatcgc aagtgctaga
    19861 tatttggcga gacaagaaaa attacctgcc ctttttagcc tatgctattt tggggatttt
    19921 ttcagttcag tattttttct atctctgtgt agaatactca aatgctacga cagcaactat
    19981 tttacagttt attagccctg tctttatcct cttttacaat cgcttggttt atcaaaaacg
    20041 agcgtcaaaa agcgctgttt tctatgtttt ggttgccatg ctgggtgttt gcttgatggc
    20101 gacaaaggga gacctctctc agttatccat gacgccgcta gctcttataa caggtttgct
    20161 gagtgccatg ggtgttatgt ttaatgttat cttgccccaa ccttttgcta agcgttatgg
    20221 ttttgttcct acggttgggt gggggatgat tttggcaggt ttgtttagca atgtcctctc
    20281 gccggtttat cagctttcct ttactcttga tatttggagt atcttgattt gcctcattat
    20341 cgctttcttt ggaacggctt ttgctttttt catttccatg aaggctgtgt ccttggtttc
    20401 tcctttggtg gttgccgtta tcagtgccag tgaacctctc tcttctgctc tcttgagtgt
    20461 tttgttctta ggattagtag tggattggtc cctccttcta gctatagcct tgattatttt
    20521 acccatgata tttttgtcta tagaagaagc gaaagaaagt agataaaaag tcttttctta
    20581 attctaaaag tgtgctatac tagaatagtc aataaaacac ggggagatag ttgtgaagag
    20641 tgtttttagg ttgtatcggt aggggcttgc ttttaccgac agcacgtttt atctcacatc
    20701 cctaaaaaat catacctaaa aacagacaaa aaggtttcaa atttgaggcc ttttttggta
    20761 gaataggtat cattataacg aaccaggagg cacctatgac tgctacaaaa atgaacgctc
    20821 aagaaattat ccaatttatc gccaatgctg aaaagaaaac cagtgtcaaa gtaacctttg
    20881 aggggcaact cgcaactgct gtgcctagct ctgttgtcaa actaggaaat gtcctattcg
    20941 gagactggaa ggacgtggct ccgcttcttg aaggtttggt agaaaatcaa gattatgttg
    21001 tcgagcaaga tgctcgtaat tctgcagttc ctttgctaga taagcgtgct atcaacgctc
    21061 gtatcgagcc aggtgctatt atccgtgacc aggtggaaat tggtgacaat gctgttatca
    21121 tgatgggagc tgttatcaat atcggtgctg aaatcggtgc tggaaccatg attgacatgg
    21181 gtgccatcct tggtggccgt gccatcgttg gaaaaaatag ccacgttggt gcaggtgcag
    21241 ttttggcagg tgtgattgag ccagctagtg ctgaaccagt ccgtgtcgga gacaatgttc
    21301 tcatcggggc taatgcagtg gttatcgaag gagtccaaat cggtagtggt tcagttgtcg
    21361 cagcaggagc tattgttacc caagatgtcc cagaaaacgt ggtagtagca ggtgttccag
    21421 ctcgtattat caaagaaatt gatgcccaaa ctcaacaaaa aacagcgcta gaggatgcgc
    21481 ttcgtacctt gtaattgtaa aagtaaaaaa gaggcggaac cctttttcca gcctctttct
    21541 gctatatcgg aggacagata gatgttagat ttgattcaga ctagacgaga tttacaccag
    21601 attccagaga ttggcttgga ggagttcaag actcaggctt atttgctgga tgtgattgag
    21661 aaattgacta cgggcaagga ttttgttcaa attcgtactt ggcggacagg gattttggtc
    21721 tacctgcagg gaagtcagcc ggagcgaacc attggttggc ggacagatat tgatggcctg
    21781 cctatcgtcg aacaaacagg tctacctttt gcttctcaac accaaggtcg catgcatgcc
    21841 tgtggccatg attttcatat gaccattgcc ttaggctgtc ttgagcgcgc ccttgaggag
    21901 caacccaaga ataatctgct ctttctattt cagcctgctg aagaaaatga agctggtggt
    21961 atgctcatgt atgaggacga tgcttttgga gattggttgc cagatcaatt ttatggcctc
    22021 catgtccgtc cagatttgaa agtcggccag attgcgacta atactcatac actctttgca
    22081 ggaacttgcg aggtgaagat ccgtttcaaa ggcaaaggtg gccacgcagc ttttcctcat
    22141 gaagccaatg acgccttggt ggcggctagt tactttgtga cccaagtgca gtcagttgtt
    22201 agccgcaatg tcaacccaat cgagggagca gtggtgacct tcggcgtttt tcaagctgga
    22261 accaccaaca atgtcatcac agacacagct tttttacatg gaactattcg tgccttgaca
    22321 caggacatga gtctcttggt gcaaaagagg gtaaaaacag ttgcagaagg ggttgcagct
    22381 gcctttgata tggaagtcga agtggaactc aaacaaggtg gatacctacc tgttgagaac
    22441 aatccagcct tggcgcgtga actgatggac ttctttgacg aaaaagacgg aatcgagttg
    22501 attgatatcg aacctgctat gacaggcgag gactttggtt atctcctttc aaaggttgat
    22561 ggcgtgatgt tttggctagg tatcgatagt ccctacgctc ttcatcaccc tcaaatgagt
    22621 cctaaggaag aagtcttagc tattggggtg gctgcggtgt ctagtttcct gaaaaagaag
    22681 gcagcagaat agagggcttg tctatgaaat cggaattacg caagcaagtc ttgcatgaaa
    22741 tgaaggctat atctcaagag caaaaacagg ctatagacca agctttaacc gagcgaattt
    22801 tacaacaccc cttttatcaa gaagccaagg tcatcgcaac ctacctctct ttttctcatg
    22861 agtttcaaac gcgggaactg attgagcagg cgctgaagga cggcaagaag gttttaatac
    22921 ccaaaactta tcccaagggg cgcatggact ttgtagtcta tgatccgcag cagttggtaa
    22981 aaactgcctt tgccttactg gagccacagg gagatttgga agtggtggat gcatctcaga
    23041 ttgatttgat tcatgttcct ggcctggctt ttacgacgga tggatatcgg attggatatg
    23101 gtggaggtta ttatgaccgc tatctggaac atttttctgg tcatactttg agtacggttc
    23161 atccttgtca aattcaggac tttatacctg aaaaccatga tattcctgtt caggaggtat
    23221 taattgatga aggaaatctt tgatagacgt taccctgtga cgagtttctt cctcttagtg
    23281 acggccttgg tatttttact aatgttggtc actgcaggcg gaaactttga cagggcagat
    23341 acattatttc gatttggagc catgtatggg ccagctattc gcctctttcc cgagcaggtt
    23401 tggcgtctct tgtctgccat ttttgttcat attgggtggg aacatttcat tgttaatatg
    23461 ctttcacttt attatcttgg aaggcaggta gaggagattt tcggttctaa gcagtttttc
    23521 tttctctatc ttttatcagg aatgatgggc aatctctttg tttttgtatt tagtcctaaa
    23581 tccttagcag caggcgcctc tacctctctt tatgggctat ttgccgcgat tattgttctt
    23641 cgctatgcaa ctcgcaatcc ttatatccaa cagctagggc aatcctatct gacacttttt
    23701 gtggttaaca ttattggaag tgttctgatt ccaggaatca gcctagcagg ccatatcggt
    23761 ggtgcagttg gtggcgcatt tctagcagtt atctttccag ttagaggaga aaaacggatg
    23821 tataacacca gccagagatt aggagcggta gtcttgttcg taggactcgc cattttgctt
    23881 ttctacaagg gaatgggaat gtgacgaagt tgaaagaaaa tttgtgtaat gaaaaaagat
    23941 aaggcatttt ttgaacctta tctttttatt ttattttatt ccttctcagt caattctttt
    24001 ccaagttgga tgaggtaatt cttcaaatca tctttgactt gtgggtgttt gagggcgtag
    24061 tcgatggatg ttttcatgaa gccaaacttg tctccgacat cgtaacgagc cccattgaac
    24121 tcacgagcaa atacacgttg tgttttattg agggtgtcga ttgcatctgt cagctgaatt
    24181 tcatttcctg cacctggagc ttggttttcg aggatttgga aaatttcagg cgtgaggagg
    24241 tagcgtccga taatagcaag gtcgctagga gcgtcctctg gagctggttt ttcaacaaag
    24301 gtttcaacac tgtaaagacc atcttttcct tcgccttgcg gagcaataac cccgtaagca
    24361 gatacttcgt catgagggac tggcatgaca gcgatagtag acgcgtgggt acgctcgtag
    24421 tcatccatga gttgtttggt aagtggaaca gccttttcgt ctgtgatatc catcaagtca
    24481 tcaccaagca taacgacaaa aggttcattt ccgacgaaag ccttggcttg caaaacagca
    24541 tctccgagac cgcgtggatg agtttggcgg ataaaatgca gccgcatgtc agttgtttta
    24601 tcaactagct tcaaaagatc tgttttccct ttttctttga ggttatattc caattcgaag
    24661 tttgaatcga agtggtcctc aatagaacgt tttgatttac cagtgacaac tagaatatct
    24721 tcaatacctg atttgagagc ctcttccacg ataaactgga tagttggttt gtctacgatt
    24781 ggcaacattt ctttggcaag ggccttggtt gctggtaaaa atcgagttcc tagtccagca
    24841 gcagggataa ctgcctttct aacttttgat gtcataaaaa tcctttctat agagggttaa
    24901 gaccactcat tttctgcttt aaattcattg ttcatgatgt cataaatggc atctttgata
    24961 ttggttccgt gataaataac ttggtaaata gcctgtgtaa tgggcatata gactccaagt
    25021 tcttgggcta gttcataggc tgctcgagtc gttgaaattc cttcgattac catgcccata
    25081 ttagcttcta tatcagctag ggattctcct cgtccgagag catctccagc tctccagtta
    25141 cgagagtgga tggaagttcc cgttacgatc aaatctccca caccagataa gccgctatag
    25201 gtcaatggac tggccccgag tgctacccct aggcgggtga tttctgctaa acctcgagcg
    25261 atgatggctg ccttagcatt atcaccaaat ccaagaccat gtaaagctcc agcaccgaca
    25321 gcaataatat ttttaagagc accagcagtt tcaaccccga taacatccgt attggtataa
    25381 agtcggaagt agtgattact aaatagctcc tgaacgtatt gagctgtttg taaatcttta
    25441 gaagcagcag ttattaaagt taggtcacgc acaatggtct cttctgcatg actaggccct
    25501 gaaacaacga cgatatcact acggagatgt tcaggaattt cttcttcaag aatggttgat
    25561 aatcgtttat ggctatcagg ttctaatccc tttgatgcgt gcatgatgat aaccttatgg
    25621 tccaaggttt gtgcaacttg ctgggcaaca agtcgtgtca cttttgttgg gacaacaaac
    25681 aaaatcgcat ccacattttt caatgtttct gctaagtcgg tgtaggcaat gatattttcg
    25741 tctagaacga catctttaaa gtagtgctta ttagtatggt gtgtattaat ttcattgatt
    25801 tgctcgggaa gatttcccca aatacgtacc tcgtgtccat tgtcatttaa gacttgtgaa
    25861 agggcggttc cccaagaacc aggccccaag acggcgacgg tttgtttttc catgatttcc
    25921 tccttgatag atttctttct cttattctat catattctag gggattttgc acttgcatta
    25981 ctggggtatg gtggaaaaat acacaaagac cgagatgaag ggataaactc ttagtcttta
    26041 gttaaagtga gaagaaatct gatagatagt ttgattcagt atatgcttat aatagaggta
    26101 aacaactcag gaagttcttg taggttgcga gagtttggcg aaaaaattaa aagattacgt
    26161 ttggctaaaa aaatcagtcg ttcagaattt tgtggtgatg agtctgaatt aagtatccgt
    26221 caattaatta gaattgaaaa tggagaatcc agaccaacac taacaaagtt aaaatatatt
    26281 gctgaacgtt tggaggttga agattacaag ttgatgccaa gttatataga gttggataag
    26341 gaatacctag aattgaagta tttcttgatg aggactccta catacgaaga tgaaactatc
    26401 gcccaaaaga aagagagtgt ttttgataag atttttgaag agtattatga taggctacct
    26461 gaggaagaaa gatttatcat cccaaattat tcatatctag cactagcgaa ctacacagtt
    26521 caaaaattac cagaaaagct agttgaaata ctgtccttct ggtgattttg cttaatttct
    26581 gatgttcgag acatgattga ggagatttgt cttgattttt tcctaaaaaa gggcagactc
    26641 ctcccttggt ttgatgctcg atttttaaaa taaggtgact tattctgtta ggcagttttc
    26701 ccctgccctc tagctctata tggaacaggg agtatcagat ttatctggca gattgtatca
    26761 aataaggctt gaaactgttt tgaataggcg tatagacttg agaatttgag aatatgtcgt
    26821 ctagcagtag agacatattt tccggcaata tgaaggaaga gacgtcgaaa acgcttgata
    26881 gtcaaggcct ttacttcatc accagctagc tgctttaaaa agaggtagag attataagcc
    26941 agacagccca tcatcatacg tacttcattc ttaatcatgg tcgaactatc tgtcttatcc
    27001 ccaaagaatc ctgctttcct ttctttgata aagttttcag cattccctcg ttcacgatag
    27061 aattgaaaca gctcctcact atctacactg cttaaattgg tcaaatgaac ttttttacaa
    27121 ccataaaaaa gagcacttaa tcgtactctt ctcttttaag gattagttga attaattcaa
    27181 atccactagt tctcctgttt ctaggtagac taggcgttca caaatgttag caatgtaatc
    27241 agcgaagcgt tccagatgcc ctatgatata aaggtattga gttccattgg gaattgaggt
    27301 ttcttggtct ttcataagtc caatgatttc ctttgataag gcataataat attggtcaat
    27361 ctgttcatct ttttgagcaa tactaatagc ttttgaggct tggtgcaaag gaaaggcaac
    27421 caataaatcg gctagcatgc tgagggataa tttacccatt tggtgtaact gttcttcgtc
    27481 aggggctagt tgattttctt ttagttgcaa aacagctttg gcaatgcctg ccatatggtc
    27541 tcccatacgt tcaaggtctg aacaagaaga catgatgcta atcacaaatc gaaggtcaga
    27601 cacttgtggc tgctgcaagg ccaacaaacg ggcacaggtc aattcgatag cgctttgacc
    27661 ttggtttata gcatgatcct tattgataat tagctctgcc atctccttgt ctttggaggc
    27721 taaggccagt aaggcttttg aagctgtttc aaggacaagt tgccctagtc ctaaaaagga
    27781 ttgttctaat tcatgcaatt ctaagtcaaa ttgatttctc ataggttttt ccttccttat
    27841 ccgaaccgtc ctgaaatata gtcttctgtg cgctgatctt ttggattggt aaacacgtca
    27901 acggtatctc caaattcgca aatttctcct gttaagaaaa aagcagtttt atctgaaata
    27961 cgtgaagctt gttgcatgtt atgggtaaca atgataatcg tataatcctt ttttagttgc
    28021 tgaatgaggt cttcaatttt taaagtggag atagggtcta aggctgaagt cggctcatcc
    28081 attaacagaa tatcaggttc tactgctaaa gctcgcgcaa tgcaaaggcg ttgctgctga
    28141 ccgccagata aggacatggc actcttttta agatcatctt tgacttcttc ccaaatggct
    28201 gcccctttta aagatttctc cactaaggca tctaattgtt ttttgtctcg aataccatgt
    28261 gtccttgggc cataagccac gttatcatag atagacatgg caaagggatt aggctgttga
    28321 aaaaccatcc ctacacgctt acgtagctga ttaaggttga atttgctact ataaatatct
    28381 tgctcatcta agaggacttg gccttcaata tggcaagaag gaaccaaatc gttcatccgg
    28441 ttaagggttt ttagaaaagt tgatttgcca caaccagatg ggcctatcaa ggcagtaatc
    28501 tgtctttctg gtaattgaat cgaaatattt tttaaggctt gaaaatcccc gtaaaataag
    28561 tctaggtgtc tgactgaaaa tgttcccata ctaggaagct cctttcacaa gttttcgaga
    28621 taataagctt gatagagtat ttatcattaa aacagtaata atcaaaatca caccggtagc
    28681 ataggcttca ttgacatgta gcccctcact tgacagcata tacatatgca gggctagaga
    28741 acgacctgaa gacatgagac tacttggcgt attggtagag gtacctaatg tatacatgag
    28801 ggcagctgtc tcaccaacga tacggccaat agctagtatc actccagcta aaatacctgg
    28861 catggcaact ggtagaacaa ttctaaaaac agtccgtaac ttacctgccc caagtccata
    28921 acttgcttga cgcatgctat cactaacaga taaaagggct tcttctgttg agcgaataat
    28981 gactggcaac accatgatga ctgaggttaa gattcctgat aacagagagt attgaaaacc
    29041 taagaagact acaaagaaga gcatgccaaa cagaccaaaa acaatggaag gaatcccaga
    29101 caaggtatct gaggccaatc gcatgatttt aacacaaagg gaatcttttt ttgtatattc
    29161 cacaagataa aaaccagcaa aaatccctat gggcaaggct aaaagaagag caccaaagac
    29221 cagaataacg gtggaaataa tcgctggcat aagggaaatg ttctcagaag tataagtcca
    29281 agaaaagagg gatagactta gatgaggtaa acctttgatg aggataaaac caatgattaa
    29341 aaagagagag ccaaaggtta aagctgaaaa acaataaacg agaagtttta gcaggtattt
    29401 actcataaga tgattttcct ttcaagtagg caaagtaggc attaatcaag agaataagga
    29461 aaaagagaac tgctgaggtt gcaataaggg cttccctatg ctgacctgat gcgtaagcca
    29521 tttccagaac aatattggtt gttaaggttc tggttcctga aaagagtcca cttggaataa
    29581 tcggctggtt gcctgccacc aaaataactg ccatggtttc acctactgcg cgaccgatgc
    29641 ctaaaataac tgctgataaa ataccagatc tcgcagctgg caagatgaca ctaaaaatac
    29701 tccgttcatg actagctcct agagccaagc taccagaata atacgttttg ggaactgttc
    29761 ggatagcaga ttctgacaaa ctgataatgg ttggcaaaat cattattcct aatagtaacg
    29821 aagcggttag gacactcatg ccatttccta aaaagcttct aatccaaggc accaataatt
    29881 gtaggccgaa aaaaccataa acaatagatg gaatggccgc catcaagttg atagctgatt
    29941 ttaagaagcc atagacgggc tttggacaat aataaaccat aaacaccgat gtcaagatgc
    30001 ctgttggcac cccaatcaca atcgctccta aggtaattaa taaggaacca acgatcattg
    30061 gtaaaatacc atagcttgcc ggaatgttcg ttggcgacca atcactgcct aataaaaaac
    30121 gggcaaagcc gtagttagcc atgaaaggta agccattact aaaaataaag aaacagatta
    30181 gcaaaatagc tacaacagct actgttgcac tcatgaaaaa aattgcccta aaaactgctt
    30241 ctttgaaggc ttgttttatc acatcttgtc ctttctagtg aagaaagtaa gggagatacg
    30301 acacctccct acttgccttc tttatcttat tgtacgatga aacgtctgca tctctttaga
    30361 gatttatgga gcaaacattt tatttaatct tgtcccaggt ggttaatttg ccactaaaaa
    30421 cgtctgcaag ttcagccata ctgacttggc ttgccttatt gtcattattg accacaacag
    30481 caataccgtc taaagcaata gcatcatggg tgagactctt accttcttca ggagttaatt
    30541 ccctagaaac cataccaata tcagcggttt tctccttaac agcggtaata cctgctgaag
    30601 acccattaga ggtaatatca atcgtaactt ctggattttc ttttttataa gcttctgcta
    30661 atttttccat taaagaagat actgaagtgg aacctacaac agacaacttg cctgataagt
    30721 gttggcttgt atattctgtg gtttcagttt tagcttcaat aaatttatta tctgtgacca
    30781 cttgttgacc ttgtttggag tggataaagc tgataaaatc ttgacctagc ttggaaagat
    30841 tagaagacca aacaatgttg aagggacgtt gaagagggta ttcaccatct aaaactgtgt
    30901 ctcgactagc cttgacacca tcaatctcta aagccttgac agatttcgtt aaagatccca
    30961 aggagatgta gccgatagca ttagcattcc cttgaactgc tgagagaaca ccttctgtac
    31021 tattttgaat cacagctgtt ttggcagtgt tgtcaatttt tttatcaccg tcttttttga
    31081 gaatccctgt gatttctgtg aaggcacccc gtgttccaga gccattttct cgtgaaatca
    31141 cctcaatcgt tcctgaagct gactgtttgg aagcagctga ctgattgcca caggcaacaa
    31201 gcccaaatcc tgataagcca atggctgcaa gagtaagcat ttttttgaat ttcataataa
    31261 tcacctttat ctctatgtat ttttcttgtg taggcttact acatttatag tctaacaagt
    31321 ctttgtaaag gtttatccct gattcatgta aagattgtgt aaagaatcaa aaaaagccac
    31381 ttttgaaaaa tggctgctcc taaaaatagc tttaaaaatt attagtcctg tgcgaaagat
    31441 tggttaggaa gaaaaatcgt gaagcaactg cctctgccaa gctgactcgt caccgtgact
    31501 tggccaccta ataattgact gagttctttg acaatggcaa ggccaagacc agtgccacca
    31561 gtttgtctgc ttcgaccttt attaactcgg taaaaacgtt caaaaatacg atcctgctct
    31621 aattgactaa taccaatccc tgtatctgat acagaaatct taatgccttc gttcaccttt
    31681 tgggtcttga cctcaatttt tcccccttgt tcagtgtaac ggatggcatt ggataaaaga
    31741 ttgagtaaga tttgggaaag taattgacta tctgatacga gggtgacatc atctggcacc
    31801 tgcaccttta gctgtaaatc cttcttcttg agctgaggtt gcaagctttg agtcaaatcc
    31861 tgtacaaatt cagccaaaga aagggtcgtc cattgtatag gcatttgttg agccttagat
    31921 aaggtaagaa gatgctcaac aatatgctca agacgcaaac tttctttgta aataatgtct
    31981 agaaagtcat ccttgagcgc ttcttcttca gctgacatcc ccttaatggt ttcagcaaag
    32041 cccttaattg aagtaactgg tgtcctcaat tcatgggagg catttgagac aaaggctaaa
    32101 tttaactttt cataagttct aatcgttgtt aaatcatata gcaagacgag cacagcttcc
    32161 acagattggg tggggctaaa aacgggaact gctgtcactt ctaaaatcaa gtcaccctca
    32221 tgaaacccac ttacttcttg ttttaacctt gttttttgat caaaggcttg gtgaactaaa
    32281 ttccgaatat ccatccgttt gaggtcatca agtgaactta tgtcgccgtc cacatcggga
    32341 aaataatgag gcagagagcg actggataat aacatctgac cttgagcgga aactaaaaac
    32401 gtccccatgg ttaggtgcga cagaagaacc tccattgttt cggctaggtc cttgtattgc
    32461 tgatcctgtt gggagacttt ggtttttagg ccagacacat actgagccaa agactttaag
    32521 tcttcttgcc ctttttctaa aaagtattca ctactggtca agagaggttg gtgcaaggtc
    32581 tcaaaagcaa cttcccattt ccaaaggcaa aagagccagt agccaccttg tcccaaagaa
    32641 agggctagaa gaaagagacc gatgccttta ctgatccaag ttaatgccat ccctgcaatc
    32701 agaatgaggc taacacttag attgactagc caaaattgaa ggtagcgttt catctataac
    32761 tccttgaact tataaccata accccgaatg gttcgaataa attgaggggc tttaggattg
    32821 tcttcaattt tttccctcaa cttaccaata tgaacgtcca ccaaacgtgt ttcctgccca
    32881 aagtcatacc cccagatacg ttccaaaaga cgctctctag tcagtgtcat gttgggatgt
    32941 ttcataagat agagcaagag ttcaaattct tttggggtca aactcagtaa cttattcgcc
    33001 ttgtagactt catgacgctc agggtatact ttcaaggtcc caaatagcca agaatcgtca
    33061 gcgatattat ctgaatcatc tccttcttgt tctcctttag ttcgcctgag gacagccttg
    33121 acacgcgcca gcaattctct agggctaaaa ggcttggtca ggtagtcatc agcccctaat
    33181 tccaaggcca aaaccttatc aaattcatca cttttcgcag aaaccatcat aattggagtt
    33241 ttgacgcctt tggctctcag ccgcttacaa acttccatgc catctaattg tggtaacatg
    33301 atatcaagca agataaaatc aaagggttct gtttctgcca aagctaaggc cttccgtcca
    33361 tttgttacca attgagtaga aaagccttcc ttacttaaat ggtagtcaag caatttcaga
    33421 atgtgttctt catcatccac taataagact tgttttgtca tctattatct cctattggta
    33481 acattataac acaattatca gaaatcctaa cattgctaaa tcagattaaa tttgcttatc
    33541 aagactagta tctggtcaaa cgctcaatca tctccttgtg ctctggatag gtcgccagta
    33601 gatctaccct ttcaaataat tcaaaatcct caaattcaaa accaggagca acaagacaag
    33661 aaaccagagc ataatcctta tcaactgttg atccccaaat agtgccctta ggaacacagt
    33721 agtgaagttg ttgccctttg gatatgtcca ggcctaaagt gactgcttcg tagtgaccat
    33781 ctgctgtaat catgtgaaca gtaagtgggg atcctgcatg aaaataccag atttcatctg
    33841 ctgtcaatcg gtgaaaatgt gaaggattcg tttcttctaa taagaaataa atactggtat
    33901 aaagcgccct tcccttacca gcaaggttta tagtgtctga agcttttttt gtttgtctaa
    33961 aatagccacc ttcaacatgg ggagctaact ctagagttct tatcaagtct tctttatcca
    34021 tcggggccaa tgggttgaag taactcttgt tcaaagtggt tttacgattt caagaactcc
    34081 tctcagttct gaggacacgg taatgattga tgcgacggaa gtacaaatca atcgccctaa
    34141 aaaaagaatt agcgaatgat tctggtaaaa agaaatttca cgctatgaag gctcaagcga
    34201 ttgtcacaag tcaagggaga attgtttcta ttgccatgat atgaagttgt tcaaaatgag
    34261 ttgcagaaat atcggacaag ctggtaaaat cttggctgac agtgattatc aagggctcat
    34321 gaagatatat cctcaagcac aaactccacg taaatccagc aaactcaagc cgctaacagc
    34381 tgaagataaa gcctataacc atgcgctatc taaggaaaga agcaaggttg agaacatctt
    34441 tgccaaagta aaaacgttta aaat
//
LOCUS       DAVHTH010000018        33903 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.018, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000018 DAVHTH010000000
VERSION     DAVHTH010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33903)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33903)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33903
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.018"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            <1..96
                     /locus_tag="VVR63_000900"
     CDS             <1..96
                     /locus_tag="VVR63_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEU6128930.1"
                     /translation="IVDYIDYYNNKRIKVKLKGLSPVQYRTKSFG"
     gene            complement(224..427)
                     /locus_tag="VVR63_000901"
     CDS             complement(224..427)
                     /locus_tag="VVR63_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6128931.1"
                     /translation="MIKLYSPYAFLSKYLGAILLSFFCYYAKEIGCNNLTLSVWNDNE
                     GALRFYQRQGMKPQETTMEMIID"
     gene            complement(420..1502)
                     /locus_tag="VVR63_000902"
     CDS             complement(420..1502)
                     /locus_tag="VVR63_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEU6128932.1"
                     /translation="MSKLQQILTYLESEKLDVAVVSDPVTINYLTGFYSDPHERQMFL
                     FVLADQEPLLFVPALEVERASSTVSFPVVGYVDSENPWQKIKHALPQLDFKRVAVEFD
                     NLILTKYHGLKTVFETAEFDNLTPRIQRMRLIKSADEVQKMMVAGLYADKAVHVGFDN
                     ISLDKTETDIIAQIDFAMKREGYEMSFDTMVLTGDNAANPHGIPAANKVENDALLLFD
                     LGVLVNGYASDMTRTVAVGKPDQFKKDIYNLTLEAQQAALDFIKPGVTAHEVDRAARE
                     VIEKAGYGEYFNHRLGHGIGMDVHEFPSIMEGNDMVIEEGMCFSVEPGIYIPGKVGVR
                     IEDCGVVTKDGFDLFTSTSKDLLYFD"
     gene            complement(1628..2410)
                     /locus_tag="VVR63_000903"
     CDS             complement(1628..2410)
                     /locus_tag="VVR63_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HEU6128933.1"
                     /translation="MVYTSLSSKDSNYPYQLNIAHLYGNLMNTYGDNGNILMLKYVAE
                     KLGAHVTVDIVSLHDDFDENHYDIAFFGGGQDFEQSIIADDLPAKKESIDNYIQNDGV
                     VLAICGGFQLLGQYYVEASGKRIEGLGVMGHYTLNQTNNRFIGDIKIHNEDFDETYYG
                     FENHQGRTFLSDDQKPLGQVVYGNGNNEEKVGEGVHYKNVFGSYFHGPILSRNANLAY
                     RLVTTALKKKYGQDIQLPAYEDILSQEIAEEYSDVKSKADFS"
     gene            complement(2410..3753)
                     /locus_tag="VVR63_000904"
     CDS             complement(2410..3753)
                     /locus_tag="VVR63_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HEU6128934.1"
                     /translation="MNLKTTLGLLAGRSSHFVLSRLGRGSTLPGKVALQFDKDILQSL
                     AKNYEIVVVTGTNGKTLTTALTVGILKEVYGQVLTNPSGANMITGIATTFLTAKSSKT
                     GKNIAVLEIDEASLSRICDYIQPSLFVITNIFRDQMDRFGEIYTTYNMILDAIRKVPT
                     ATVLLNGDSPLFYKPTIPNPIEYFGFDLEKGPAQLAHYNTEGILCPDCQGILKYEHNT
                     YANLGAYICEGCGCKRPDLDYRLTKLVELTNNRSRFVIDGQEYGIQIGGLYNIYNALA
                     AVAIARFLGADSQLIKQGFDKSRAVFGRQETFHIGDKECTLVLIKNPVGATQAIEMIK
                     LAPYPFSLSVLLNANYADGIDTSWIWDADFEQITDMDIPEINAGGVRHSEIARRLRVT
                     GYPAEKITETSNLEQVLKTIENQDCKHAYILATYTAMLEFRELLASRQIVRKEMN"
     gene            complement(3852..5168)
                     /locus_tag="VVR63_000905"
     CDS             complement(3852..5168)
                     /locus_tag="VVR63_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000958936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HEU6128935.1"
                     /translation="MLTYDLIVIGFGKAGKTLAGKLASAGKKVALVERSKAMYGGTCI
                     NIGCIPTKTLLVAAEKDLSFEEVIATKNTITGRLNGKNYATVAGTGVDIFDAEAHFLS
                     NKVIEIQAGDEKKELTAETIVINTGAVSNVLPIPGLATSKNIFDSTGIQSLDKLPEKL
                     GILGGGNIGLEFAGLYNKLGSKVTVLDALDTFLPRAEPSIAALAKQYMEEDGIELLQN
                     IHTTEIKNDGDQVLVVTEDETYRFDALLYATGRKPNVEPLQLENTDIELTERGAIKVD
                     KHCQTNVPGVFAVGDVNGGLQFTYISLDDFRVVYSYLAGDGSYTLEDRLNVPNTMFIT
                     PALSQVGLTESQAADLKLPYAVKEIPVAAMPRGHVNGDLRGAFKAVVNTETKEILGAS
                     IFSEGSQEIINIITVAMDNKIPYTYFTKQIFTHPTLAENLNDLFAI"
     gene            5361..6587
                     /locus_tag="VVR63_000906"
     CDS             5361..6587
                     /locus_tag="VVR63_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
                     /protein_id="HEU6128936.1"
                     /translation="MKSNRYIIAFAGVILHLMLGSTYAWSVYRNPIIEKTGWDQASVA
                     FAFSLAIFCLGLSAAFMGRLVEKFGPKVMGSLSAFLYAGGNILTGFAIDRQELWLLYL
                     AYGILGGLGLGAGYITPVSTIIKWFPDKRGLATGLAIMGFGFASLLTSPIAQHLIAGV
                     GIVETFYILGASYFIIMLLASQFIKRPNEQELAILSSSGKEKTASLTQGMAANQALKS
                     NRFYMLWIIFFINIACGLGLISAASPMAQEMAGLSTSHAAVMVGVLGIFNGFGRLLWA
                     SLSDYIGRPLTFSILLLVNLFFSLSLWLFTDSVLFVVAMSILMTCYGAGFSLIPAYLS
                     DIFGTKELAALHGYILTAWAMAGLAGPILLAETYKMAHSYTQTLFVFLILYSIALALS
                     YYLGRSIKKESQKPLT"
     gene            6786..8360
                     /locus_tag="VVR63_000907"
     CDS             6786..8360
                     /locus_tag="VVR63_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU6128937.1"
                     /translation="MKFNELNLSADLLAEIEKAGFVEASPIQEQTIPLALEGKDVIGQ
                     AQTGTGKTAAFGLPTLEKIRIEEATIQALVIAPTRELAVQSQEELFRFGRSKGVKVRS
                     VYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALKLQDIETLILDEADEMLNMGF
                     LEDIEAIISRVPENRQTLLFSATMPDAIKRIGVQFMKAPEHVKIAAKELTTELVDQYY
                     IRVKEQEKFDTMTRLMDVAQPELAIVFGRTKRRVDELTRGLKIRGFRAEGIHGDLDQN
                     KRLRVLRDFKNGNLDVLVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KSGQSITFVAPNEMGYLQIIENLTKKRMKGLKPASVEESFQSKKQVALKKIERDFADE
                     TIRANFEKFGKDARKLAAEFTPEELAMYILSLTVQDPDSLPEVEIAREKPLPFKPSGN
                     GFGGKAKGGRGGRRGDDRRERDRRGNGRRDEFKKGSRGNDRFDKEKRYRKDNKKPRNT
                     LSEKQTGFVIRNKGDK"
     gene            8625..9413
                     /gene="codY"
                     /locus_tag="VVR63_000908"
     CDS             8625..9413
                     /gene="codY"
                     /locus_tag="VVR63_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HEU6128938.1"
                     /translation="MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNAC
                     IINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYVQGANMIYETEANLPVEHDMSIF
                     PVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLN
                     FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGKLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVLISDIFEEVKKRDY"
     gene            9413..9988
                     /locus_tag="VVR63_000909"
     CDS             9413..9988
                     /locus_tag="VVR63_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEU6128939.1"
                     /translation="MTKALISIDYTEDFVADSGKLTAGAPAQAISDAISKVTRLAFER
                     GDYIFFTIDAHEENDCFHPESKLFPPHNLIGTSGRNLYGDLGIFYQEHGSDSRVFWMD
                     KRHYSAFSGTDLDIRLRERRVSTVILTGVLTDICVLHTAIDAYNLGYDIEIVKPAVAS
                     IWPENHQFALGHFKNTLGAKLVDENLNELSE"
     gene            10070..10155
                     /locus_tag="VVR63_000910"
     tRNA            10070..10155
                     /locus_tag="VVR63_000910"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10104..10106,aa:Leu,seq:aag)
     gene            10438..11568
                     /gene="ugpC"
                     /locus_tag="VVR63_000911"
     CDS             10438..11568
                     /gene="ugpC"
                     /locus_tag="VVR63_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HEU6128940.1"
                     /translation="MVELNLKNIYKKYPNSEHYSVEDFNLNIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDITEGTASIDGVVVNDVAPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYSKEDINKRVQEAAEILGLKEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGATTIYVTHDQTEAMTLADRIVIMSATKNPAGT
                     GTIGRVEQIGTPQEVYKNPVNKFVAGFIGSPAMNFINVKLVGSEIVSDGFRLKVPEGA
                     LKVLREKGYEGKELIFGIRPEDVNAEPAFLETFPDCVVKATISVSELLGSESHLYCQV
                     GKDEFVAKVDARDYLQTGATVELGFDLNKAHFFDVETEKTIY"
     gene            12069..12827
                     /locus_tag="VVR63_000912"
     CDS             12069..12827
                     /locus_tag="VVR63_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEU6128941.1"
                     /translation="MSEAGHKFLAKLGKKRLRPGGKRATDWLIAEGGFSKEKRILEVA
                     CNRGTTAIELAQRFGCKITAVDMDAQALEVAKKSAGTAGVAHLISFERANAMKLPYQD
                     ASFDIVINEAMLTMQADQAKKKCVMEYLRVLKPGGLLLTHDVLLKEAKESIRQELSQA
                     IHVNVGPLTQDGWEQVMIESGYCDVKALTGEMTLMKLSGMIYDEGLLGTLKICVNACK
                     KENRKQFLTMYKMFAKNKQKLGFIAMASYKSSKR"
     gene            12915..13427
                     /locus_tag="VVR63_000913"
     CDS             12915..13427
                     /locus_tag="VVR63_000913"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HEU6128942.1"
                     /translation="MNLKDYIATIENYPKEGITFRDISPLMADGNAYSYAVREIVQYA
                     TDKKVDMIVGPEARGFIVGCPVAFELGIGFAPVRKPGKLPREVISADYEKEYGVDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGVMAGCAFLVELDELNGREKIG
                     DYDYKVLMHY"
     gene            13609..14553
                     /locus_tag="VVR63_000914"
     CDS             13609..14553
                     /locus_tag="VVR63_000914"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HEU6128943.1"
                     /translation="MPIRIDKKLPAVEILRTENIFVMDDQRAAHQDIRPLKILILNLM
                     PQKMVTETQLLRHLANTPLQLDIDFLYMESHRSKTTRSEHMETFYKTFPEVKDEYFDG
                     MIITGAPVEHLPFEEVDYWEEFRQMLEWSKTHVYSTLHICWGAQAGLYLRYGVEKYQM
                     DSKLSGIYPQDTLKEGHLLFRGFDDSYVSPHSRHTEISKEEVLNKTNLEILSEGPQVG
                     VSILASRDLREIYSFGHLEYDRDTLAKEYFRDRDAGFDPHIPENYFKDDDVNQVPCLC
                     WSSSAALFFSNWVNHAVYQETPFDWRKIEDDASAYGYL"
     gene            14562..15239
                     /locus_tag="VVR63_000915"
     CDS             14562..15239
                     /locus_tag="VVR63_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HEU6128944.1"
                     /translation="MTYLDAFKSGTLVLPSALLLHFKELFPSSDDFLVWQFFYLQNTT
                     GLEEMSPSQIAERIGKEISDVNQSISNLTERGLLQYRTIELNGEIELLFDASLALERL
                     DDLFGAVHSSSDQLTPQNQLKDLVETFQQELGRLLTPFEIEDLTKTLKEDGTSADLIK
                     EALREAVLNGKPNWKYIQAILRNWRHEGIKSVAQIEAKRAEREASNPQLTQVSADFRN
                     AMDLWKD"
     gene            15337..16095
                     /locus_tag="VVR63_000916"
     CDS             15337..16095
                     /locus_tag="VVR63_000916"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HEU6128945.1"
                     /translation="MSRKPFIAGNWKMNKNPEEAKAFVEAVASKLPSSDLVEAGIAAP
                     ALDLTTVLAVAKGSNLKVAAQNCYFENAGAFTGETSPQVLKEIGTDYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGMLPIICCGESLETYEAGKAAEFVGAQVSAALAGLTAEQV
                     AASVIAYEPIWAIGTGKSASQDDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NVASYMACPDVDGALVGGASLEAESFLALLDFVK"
     gene            16133..17638
                     /gene="lytC"
                     /locus_tag="VVR63_000917"
     CDS             16133..17638
                     /gene="lytC"
                     /locus_tag="VVR63_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078138769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase LytC"
                     /protein_id="HEU6128946.1"
                     /translation="MSVTFFIGEQRLKTKIGLASICLLGLATSHVAANETEVAKTSQD
                     TTTASSSSEQNQSSNKTQTSAEVQTNAAAHWDGDYYVKDDGSKAQSEWIFDNYYKAWF
                     YINSDGRYSQNEWHGNYYLKSGGYMAQNEWIYDSNYKSWFYLKSDGAYAHQEWQLIGN
                     KWYYFKKWGYMAKSQWQGSYFLNGQGAMMQNEWLYDPAYSAYFYLKSDGTYANQEWQK
                     VGGKWYYFKKWGYMARNEWQGNYYLTGSGAMATDEVIMDGARYIFAASGELKEKKDLN
                     VGWVHRDGKRYFFNNREEQVGTEHAKKIIDISEHNGRINDWKKVIDENEVDGVIVRLG
                     YSGKEDKELAHNIKELNRLGIPYGVYLYTYAENETDAENDAKQTIELIKKYNMNLSYP
                     IYYDVENWEYVNKSKRAPSDTDTWVKIINKYMDTMKQAGYQNVYVYSYRSLLQTRLKH
                     PDILKHVNWVAAYTNALEWENPYYSGEKGWQYTSSEYMKGIQGRVDVSVWY"
     gene            18136..18654
                     /locus_tag="VVR63_000918"
     CDS             18136..18654
                     /locus_tag="VVR63_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HEU6128947.1"
                     /translation="MVELKKEAAKDVATLTKAAPVALAKTKEVLNQAVADLYVAHVAL
                     HQVHWYMHGRGFLVWHPKMDEYMEALDGHLDEISERLITLGGSPFSTLTEFLQNSEIE
                     EEAGEYRNVEESLERVLAIYRYLITLFQKALDVTDEEGDDVTNDIFVGAKAELEKTVW
                     MLAAELGQAPGL"
     gene            18784..19290
                     /locus_tag="VVR63_000919"
     CDS             18784..19290
                     /locus_tag="VVR63_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HEU6128948.1"
                     /translation="MTKKIVAIWAQDEDGVIGKDNRLPWHLPAELQHFKETTLNHAIL
                     MGRVTFDGMGRRLLPKRETLILTRNSEEKLDGVATFHDVQSVLDWYHAQDKNLYILGG
                     KQIFQAFEPYLDEVIVTHIHARVEGDTYFPEEFDLSLFETVSSKSYTKDEKNPYDFTI
                     QYRKRKEV"
     gene            19290..19460
                     /locus_tag="VVR63_000920"
     CDS             19290..19460
                     /locus_tag="VVR63_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000442275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6128949.1"
                     /translation="MERSLFGLFTAFLCFICLLAGAQAFRKKRYGLSILLWLNAFTNL
                     VNSIHAFYMTLF"
     gene            19492..20724
                     /gene="clpX"
                     /locus_tag="VVR63_000921"
     CDS             19492..20724
                     /gene="clpX"
                     /locus_tag="VVR63_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002874765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HEU6128950.1"
                     /translation="MSTNRKNDMMVYCSFCGKSQEEVQKIIAGNNAFICNECVELAQE
                     IIREELVEEVLADLSEVPKPIELLHILNHYVIGQDRAKRALAVAVYNHYKRINFHDTR
                     EESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
                     ILLKLLQAADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGT
                     VASVPPQGGRKHPQQEMIQVDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAI
                     DENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRILKEPRNALVKQYQ
                     TLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLV
                     RITKEAVDGTDKPILETA"
     gene            20733..21320
                     /locus_tag="VVR63_000922"
     CDS             20733..21320
                     /locus_tag="VVR63_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002915299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HEU6128951.1"
                     /translation="MELNTHNAEILLSAANKSHYPQDELPEIALAGRSNVGKSSFINT
                     MLNRKNLARTSGKPGKTQLLNFFNIDDKMRFVDVPGYGYARVSKKEREKWGRMIEEYL
                     TTRENLRAVVSLVDLRHDPSADDVQMYEFLKYYEIPVIIVATKADKIPRGKWNKHESA
                     IKKKLNFDPSDDFILFSSVSKAGMDEAWDAILEKL"
     gene            21331..21711
                     /locus_tag="VVR63_000923"
     CDS             21331..21711
                     /locus_tag="VVR63_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HEU6128952.1"
                     /translation="MAKTIHTDKAPKAIGPYVQGKIVGNLLFASGQVPLSPETGEIVG
                     ENIQEQTEQVLKNIGAILAEAGTDFDHVVKTTCFLSDMNDFVPFNEVYQTAFKEEFPA
                     RSAVEVARLPRDVKVEIEVIAEIG"
     gene            21763..22653
                     /gene="rapZ"
                     /locus_tag="VVR63_000924"
     CDS             21763..22653
                     /gene="rapZ"
                     /locus_tag="VVR63_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HEU6128953.1"
                     /translation="MTKKQLHLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALLPK
                     FLQLVEIKEDNPKLALVVDMRSRSFFSEIQAVLDELENQDGLDFKILFLDAADKELVA
                     RYKETRRSHPLAADGRILDGIKLERELLAPLKNMSQNVVDTTELTPRELRKTLAEQFS
                     DQEQAQSFRIEVMSFGFKYGIPIDADLVFDVRFLPNPYYLPELRNQTGVDEPVYDYVM
                     NHPESEDFYQHLLALIEPILPSYQKEGKSVLTIAMGCTGGQHRSVAFAKRLVQDLSKN
                     WSVNEGHRDKDRRKETVNRS"
     gene            22650..23627
                     /locus_tag="VVR63_000925"
     CDS             22650..23627
                     /locus_tag="VVR63_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HEU6128954.1"
                     /translation="MRKPKITVIGGGTGIPVILKSLREKDVEIAAIVTVADDGGSSGE
                     LRKNMQQLTPPGDLRNVLVAMSDMPKFYEKVFQYRFSEDAGAFAGHPLGNLIIAGLSE
                     MQGSTYNAMQLLSKFFHTTGKIYPSSDHPLTLHAVFQDGTEVAGESHIVDHRGIIDNV
                     YVTNALNDDTPLASRRVVQTILESDMIVLGPGSLFTSILPNIVIKEIGRALLETKAEI
                     AYVCNIMTQRGETEHFTDSDHVEVLHRHLGRPFIDTVLVNIEKVPQEYMNSNRFDEYL
                     VQVEHDFVGLCKQVSRVISSNFLRLENGGAFHDGDLIVDELMRIIQVKK"
     gene            23624..24535
                     /gene="whiA"
                     /locus_tag="VVR63_000926"
     CDS             23624..24535
                     /gene="whiA"
                     /locus_tag="VVR63_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HEU6128955.1"
                     /translation="MSFTVAVKEEILGQHHLSRHELSAIIKMSGSIGLSTSGLTLSVV
                     TENAKLARHLYESFLHFYEIKSEIRHHQRSNLRKNRVYTVFTDEKVQDLLSDLHLADS
                     FFGLETGIDEAILSDEEAGRAYLCGAFLANGSIRDPESGKYQLEISSVYLDHAQGIAS
                     LLQQFLLDAKVLERKKGAVTYLQRAEDIMDFLIVIGAMQARDDFERVKILRETRNDLN
                     RANNAETANIARTVSASMKTINNISKIKDIMGLENLPVDLQEVAQLRIQHPDYSIQQL
                     ADSLSTPLTKSGVNHRLRKINKIADEL"
     gene            complement(24569..25537)
                     /locus_tag="VVR63_000927"
     CDS             complement(24569..25537)
                     /locus_tag="VVR63_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000081018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEU6128956.1"
                     /translation="MSQLYDITIVGGGPVGLFAAFYAHLRQAKVQIIDSLPQLGGQPA
                     ILYPEKEILDVPGFPNLTGEELTNRLIEQLNGFDTPIHLNETVLEIDKQEEEFAITTS
                     KGSHLTKTVIIAMGGGAFKPRPLELEGVEDYENIHYHVSNIQQYAGKKVTILGGGDSA
                     VDWALAFEKIAPTTLVHRRDNFRALEHSVQTLQESSVTIKTPFAPSQLLGNGKTLDKL
                     EITKVKSDETETIDLDHLFVNYGFKSSVGNLKNWGLDLNRHKIIVNSKQESSQAGIYA
                     IGDCCYYDGKIDLIATGLGEAPTAVNNAINYIDPEQKVQPKHSTSL"
     gene            25673..26530
                     /locus_tag="VVR63_000928"
     CDS             25673..26530
                     /locus_tag="VVR63_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001867651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HEU6128957.1"
                     /translation="MNFQQLSNLQYWTSLFASPWTIAINLIDILIVAYILYHFTKAIA
                     GTKIMILVRGVLVFILAQILANMIGLTTISWLINQIITYGVIAAVVIFSPEIRTGLER
                     LGRATDFFSNAPISAEEQMIRAFVKSVEYMSPRKIGALVAIQRVRTLQEYMSTGIPLD
                     AKISAELLINIFIPNTPLHDGAVIIKEERIAVTSAYLPLTKNTGISKEFGTRHRAAIG
                     LSEVSDALTFVVSEETGGISITYNGRFKHNLTLDEFETELREILLPKEEVGLSFKERL
                     LGGWKHEKK"
     gene            26517..27296
                     /locus_tag="VVR63_000929"
     CDS             26517..27296
                     /locus_tag="VVR63_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbbR-like domain-containing protein"
                     /protein_id="HEU6128958.1"
                     /translation="MKKNSLYIISSLFFACVLFVYATATNFQNSTSARQVKTETYTNT
                     VTNVPIDIRYNSDKYFISGFASEVSVVLTGANRLSLASEMQESTRKFKVTADLTDAGV
                     GTIEVPLSIEDLPNGLTAVATPQKITVKIGKKAQKDKVKIVPEIDPSQIDSRVQIENV
                     MVSDKEVSITSDQETLDRIDKIIAVLPTSERITGNYSGSVPLQAIDRNGVVLPAVITP
                     FDTIMKVTTKPVAPSSSTSNSSTSSSSETSSSTKATSSKTN"
     gene            27320..28672
                     /locus_tag="VVR63_000930"
     CDS             27320..28672
                     /locus_tag="VVR63_000930"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HEU6128959.1"
                     /translation="MGKYFGTDGVRGEANLELTPELAFKLGRFGGYVLSQHETEAPKV
                     FVGRDTRISGEMLESALVAGLLSVGIHVYKLGVLATPAVAYLVETEGASAGVMISASH
                     NPALDNGIKFFGGDGFKLDDEKEAEIEALLDAEEDTLPRPSAEGLGILVDYPEGLRKY
                     EGYLVSTGTPLDGMKVALDTANGAASTSARQIFADLGAQLTVIGETPDGLNINLNVGS
                     THPEALQEMVKESGSAIGLAFDGDSDRLIAVDENGDIVDGDKIMYIIGKYLSEKGQLA
                     QNTIVTTVMSNLGFHKALNREGINKAVTAVGDRYVVEEMRKSGYNLGGEQSGHVILMD
                     YNTTGDGQLSAVQLTKIMKETGKSLSELAAEVTIYPQKLVNIRVENAMKEKAMEVPAI
                     KAIIEKMEEEMAGNGRILVRPSGTEPLLRVMAEAPTTEEVDYYVDTITDVVRAEIGID
                     "
     gene            28746..29120
                     /locus_tag="VVR63_000931"
     CDS             28746..29120
                     /locus_tag="VVR63_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HEU6128960.1"
                     /translation="MNLKREQEFVSQYHFDARNFEWENENGAPETKVDVNFQLLQHDQ
                     ENQVTSLIVILSFMIVFDKFVISGTISQVNHIDGRIVNEPSELNQEEVETLARPCLNM
                     LNRLTYEVTEIALDLPGINLEF"
     gene            29122..29970
                     /locus_tag="VVR63_000932"
     CDS             29122..29970
                     /locus_tag="VVR63_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEU6128961.1"
                     /translation="MKLAVFTDSSAYLSEETLQREDLFVLDIPVNIDGEEYVEGINLS
                     AEEFYQKMAQASELPKTSQPSIAKLDEILTSLKEQGYTHALGLFLSSGISGFYQNIQY
                     MVDDYEGLTIAFPDTLITSAPLGIMVESVFNWRDQGDDFASIQDKLAIQISRTSAFIM
                     VDDLDHLVKGGRLSNGAAILGNLLSIKPILYFNDQGVIEVYEKVRTEKKATKRLIEII
                     KETTASGQYRVIVIHGNAPEKAEELRQHLLDFGLGSDVSLATFGSVIGTHLGAGSIAL
                     GYIPVI"
     gene            30236..31003
                     /locus_tag="VVR63_000933"
     CDS             30236..31003
                     /locus_tag="VVR63_000933"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HEU6128962.1"
                     /translation="MSIRVIIAGFKGKMGQAACQMVLTDPDLDLVAVLDPFESESEWQ
                     GIPVFKDKADLAGFEADVWVDFTTPAVAYENTRFALENGFAPVVGTTGFTSEEIAELK
                     EFSRAQDLGGLIAPNFALGAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKT
                     AELMAEVRESIQQGAADEEELIAGARGADFDGMRIHSVRLPGLVAHQEVIFGNQGEGL
                     TLRHDSYDRISFMTGVNLGIKEVVKRHELVYGLEHLL"
     gene            31015..32199
                     /locus_tag="VVR63_000934"
     CDS             31015..32199
                     /locus_tag="VVR63_000934"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HEU6128963.1"
                     /translation="MPSEFQKALPVLEKIKEAGFEAYFVGGSVRDALLHSPIHDVDIA
                     TSSYPEETKQIFPRTADIGIEHGTVLVLDGDEEYEVTTFRTEDVYVDYRRPSAVSFVR
                     SLEEDLKRRDFTVNAFALDETGEIVDLFHGLEDLEKQVLRAVGVASERFNEDALRIMR
                     GFRFQASLGFALEPETFKAMKTLTPLLEKISVERTFVEFDKLLLAPFWRRGLASMIES
                     QAYDYLPDMASSQDKLNRLFDLETDFTFESSEQAWAALLWALEIENAQSFLKSWKTSR
                     QFAKQVQDLLIILALRENGELSKRDCYRFDLDLLLQAENLRQAQGKEVNPQVIKETYQ
                     SLTIHDKKEIQINGGILIKEYGYQPGPDLGEILTEIEFAIVDGELENNREAIHAYLRE
                     KK"
     gene            32196..>33903
                     /locus_tag="VVR63_000935"
     CDS             32196..>33903
                     /locus_tag="VVR63_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEU6128964.1"
                     /translation="MSDFIVEKLSKSVGDKTVFRDISFIIHDLDRIGLIGVNGTGKTT
                     LLDVLSGVSGFDGDVSPFSAKNDYQIGYLTQDPDFDDRKTVLDTVLSSELKEIQLIRE
                     YELIMLDYSEDKQARLERVMAEMDSLQAWEIESQVKTVLSKLGIQDLSTPVGELSGGL
                     RRRVQLAQVLLGNHDLLLLDEPTNHLDIAIIEWLTLFLKNSKKTVLFITHDRYFLDAL
                     STRIFELERAGLTEYQGNYQDYVRLKAEQDERDAALLHKKEQLYKQELAWMRRQPQAR
                     ATKQQARINRFHDLKKEVSGSSAETDLTMNFETSRIGKKVIEFQDVSFAYENKPILQN
                     FNLLVQAQDRIGIVGDNGVGKSTLLNLIAGSLEPTAGQVVIGETVRIAYFSQQIEGLD
                     ESKRVINYLQEVAEEVKTSGGSTTSIAELLEQFLFPRSTHGTLIEKLSGGEKKRLYLL
                     KLLLEKPNVLLLDEPTNDLDIATLTVLENFLQGFAGPVLTVSHDRYFLDKVATKILAF
                     EDGKIRPFFGHYTDYLDEKAFETDMANQVQKAEKEKVVKVREDKKRMTYQEKQEWASI
                     EGD"
BASE COUNT         9965 a         6265 c         7777 g         9896 t
ORIGIN      
        1 attgtagact atattgatta ctacaacaat aaacgaatta aggtaaaact aaaaggactt
       61 agtcctgtgc aatacagaac taaatccttc ggataaatta tttgtctaac tgtttggggg
      121 cagtacattt taacacttga tactatgcgt tttattgtgg gaagattttc ctcattttct
      181 agtgaaattg aactttttct aacatctttt gatagatgac ttcttaatca attatcattt
      241 ccattgttgt ttcttggggt ttcatccctt gtctttgata aaagcggaga gcaccctcgt
      301 tatcattcca gacacttagg gttagattat tgcagccaat ttctttagca taatagcaga
      361 aaaatgacaa taaaatagcc cctagatatt ttgaaaggaa agcatagggg ctatatagtt
      421 taatcaaaat aaagcaaatc tttgctggtg cttgtaaaga ggtcgaagcc atccttggta
      481 acaacaccgc agtcttcaat acgaacaccg actttaccag ggatatagat acctggttca
      541 acagagaagc acatgccttc ttcgatgacc atgtcgtttc cttccatgat agatgggaat
      601 tcatggacat ccataccgat accatgcccg agacggtggt tgaagtactc accataacca
      661 gctttttcga tgacctcacg ggcagcgcgg tccacttcat gagcagtcac acctggcttg
      721 ataaagtcaa gagcagcttg ttgggcttca agagtcaagt tgtaaatatc tttcttgaat
      781 tggtctggtt tgccgacagc gactgtacga gtcatatctg acgcatagcc attgaccaga
      841 acacccaggt caaagaggag aagagcatca ttttcaacct tattagctgc tggaatgccg
      901 tgtggattcg cagcattatc accagtcaag accatggtat caaagctcat ttcataacct
      961 tcacgtttca tggcaaagtc gatttgtgcg atgatatctg tctcagtctt atcaagagaa
     1021 atattgtcaa aaccaacatg aacagccttg tcagcataaa gacctgcaac catcattttt
     1081 tgcacttcat cagctgattt gatgaggcgc atgcgttgga tacgaggagt gaggttgtca
     1141 aactcagcag tctcaaaaac tgttttcaaa ccatggtatt tggtcaagat gagattgtca
     1201 aactcaacag cgacacgttt gaagtcaagt tgtggaagag catgtttgat tttttgccat
     1261 ggattttcag aatcgacata gcccactact gggaaggaaa cggtgctact tgcacgttct
     1321 acttcaagag ctgggacaaa gaggagaggt tcctgatccg ctaggacaaa gaggaacatt
     1381 tggcgttcat ggggatcact gtaaaaacca gtgaggtaat tgattgtgac ggggtcagat
     1441 acgacagcga cgtctagttt ttctgattca agatatgtta ggatttgttg taatttagac
     1501 atatgctacc ttctttctac ccctctattt tggcaaaaaa tgagagaaaa tgcaagggag
     1561 aagggtaaaa gaaaagacaa aaaactccga caagataacg gagttctttg atatcatttt
     1621 cctttgttta agaaaagtca gccttgcttt tgacgtcact gtactcttca gcgatttctt
     1681 ggctgagaat gtcctcatag gcagggagtt ggatgtcctg accatatttc ttcttgaggg
     1741 cagtagtaac taggcgataa gccagattgg cattacgaga gaggataggc ccgtggaagt
     1801 aggaaccaaa gacattctta taatgaaccc cttcaccgac cttttcttcg ttgtttccat
     1861 ttccatagac aacctgtccc agcggttttt ggtcatcaga gaggaaggta cgaccttggt
     1921 gattttcaaa tccatagtag gtttcatcga aatcttcatt gtgaatcttg atgtcaccga
     1981 taaaacggtt attggtctgg ttgagcgtgt agtgtcccat gacccctagc ccttcgatac
     2041 gttttcctga agcttcaaca taatattgac ccaatagttg gaaaccaccg cagatagcca
     2101 gaactacacc gtcgttttgg atgtagttgt caatgctctc ttttttagca ggtaggtcgt
     2161 ctgcaatgat actttgttca aagtcttgac caccaccgaa aaaggcgatg tcgtagtgat
     2221 tttcatcaaa gtcatcatgg agagaaacga tgtcaacggt cacatgggct cccagttttt
     2281 cagccacata cttgagcatg aggatgtttc cattgtcccc gtaggtattc atgagatttc
     2341 cgtagaggtg ggcaatgttg agctgatagg ggtaattgct atcttttgag gaaagtgaag
     2401 tataaaccat tagttcatct cctttctaac aatctgacga ctagccagca gttcacgaaa
     2461 ttccagcatg gcagtataag ttgccagaat ataggcatgc ttgcagtctt gattctcaat
     2521 ggtcttgaga acttgctcca gattactcgt ttcagtgatt ttctcagctg gatagccagt
     2581 cactcggagg cgacgagcga tttcagaatg acgaacaccg ccagcgttga tttcaggaat
     2641 gtccatgtca gtgatttgct caaagtctgc atcccagatc cagctagtgt caattccatc
     2701 tgcatagttg gcattaagga ggacagatag gctaaatgga taaggtgcta gtttgatcat
     2761 ttcgatagct tgggttgcac cgactggatt tttaatcaag acaagggtac attccttgtc
     2821 accgatatga aaggtttctt ggcgtccaaa gacagcacgg ctcttgtcaa atccctgttt
     2881 gatgagttgg gaatctgcgc cgaggaaacg ggcgatggcc acagcagcta gggcgttata
     2941 gatattatag agcccgccga tttggatacc gtattcttgg ccgtctatga caaagcgaga
     3001 gcgattgttg gtcaactcaa ccagttttgt caaacgatag tcgagatcag gacgtttaca
     3061 tccacaacct tcacagatat aggcacccaa gtttgcatag gtattatgct catatttgag
     3121 gatgccttgg cagtcaggac agagaatccc ttcggtattg tagtgagcaa gttgggctgg
     3181 tcctttttcc aagtcaaaac caaaatactc tatagggttt ggaatagttg gcttgtagaa
     3241 aagtggactg tctccgttaa ggagaacagt agcagttgga acttttcgaa tggcatccaa
     3301 tatcatgtta taggtagtat agatttcacc gaaacggtcc atctggtcac ggaagatatt
     3361 agtaatgaca aaaagactag gctggatata gtcacagata cgagatagac tggcttcgtc
     3421 aatttcgagg acggcaatat ttttcccagt ttttgaagat ttggctgtta ggaaggttgt
     3481 tgcaatccct gtaatcatgt tggcaccgct tgggttggtt agaacttgac cataaacctc
     3541 ttttaaaatg ccgacagtga gggcagttgt cagggttttt ccatttgttc cagtgacaac
     3601 gacaatctcg tagttcttag ctaggctttg taaaatatct ttatcaaatt gaagggcgac
     3661 tttccctggg agcgtacttc cacgtccaag acggcttaaa acgaagtggg aagaacgccc
     3721 agcaagaagg cccaaagtag tttttaagtt catgtttcta ttatatcaca aaagagggaa
     3781 aagacagatt tggtgtttcg tagaagtaaa aacagcccaa agagggctgt cagttaagat
     3841 gagatttcaa cttaaatcgc aaacaagtca ttcaagttct cagccaaggt tgggtgagtg
     3901 aagatttgtt ttgtgaagta agtgtaagga atcttgttgt ccatagcaac agtaatgatg
     3961 ttgatgattt cttgagaacc ttctgagaag atgcttgcac caagaatttc ttttgtttca
     4021 gtattaacaa cagctttgaa agctccgcga aggtctccat ttacgtgacc acgaggcatg
     4081 gctgcaacag ggatttcttt cactgcgtat ggaagtttca aatcagctgc ttggctttca
     4141 gtcaaaccaa cttgtgaaag tgcaggtgtg atgaacatag tatttggcac attgagacgg
     4201 tcctcaagtg tgtagctgcc atctccagca aggtagctgt aaacaacacg gaagtcatca
     4261 agtgaaatgt aagtaaattg aaggccaccg ttgacatctc caactgcaaa gacaccagga
     4321 acgtttgttt gacagtgttt gtctacttta atagcaccac gttcagttag ttcaatatct
     4381 gtattttcaa gttgaagtgg ttctacattt ggtttgcgtc cagttgcgta gagaagggcg
     4441 tcgaaacggt aagtttcgtc ttcagttacg acaagcactt ggtcaccatc gtttttgatt
     4501 tcagtagtat ggatattttg aagcaattca atgccatctt cttccatgta ttgtttagca
     4561 agagctgcga tggaaggttc tgcacgaggt aggaatgtat ccaaggcatc taggactgtg
     4621 accttgcttc caagtttgtt gtaaaggccg gcaaattcaa gaccgatatt tccgccacca
     4681 aggattccaa gtttttcagg taatttgtcc aagctttgga tacctgttga gtcaaagatg
     4741 tttttgcttg tagcaagtcc aggaattggc aagacgtttg aaacagcacc agtgttgatg
     4801 acgattgttt cagcagtcag ttctttcttt tcatcaccag cttggatttc gatgacttta
     4861 tttgaaagga agtgagcttc cgcatcaaag atatctacgc ctgtaccagc aacagtcgca
     4921 tagtttttac cgttgaggcg accagtgatc gtgtttttag tagcaatcac ttcttcaaaa
     4981 gacaagtcct tttcagcagc aactagcaag gttttagttg ggatacaacc aatgttgata
     5041 caagttccac cgtacatagc cttgctgcgt tcaacgaggg caactttttt gccagctgaa
     5101 gccaatttac ctgctagtgt tttaccagct ttaccaaatc caataacaat taaatcgtat
     5161 gttaacattt atcttcctcc tattcgaatt tcattctagc acaagaaaaa aacttttgca
     5221 caattctgct acggaaaaga cagaaaaaga taaaaacgct ttccagacaa aaaactagta
     5281 attttttgac aagcttgata aactaaaatc ctatctattt ttatataaga aagaataaat
     5341 gttcgaaaat aggaggtttt atgaaatcga atcgttatat tattgccttt gctggggtca
     5401 ttttacactt aatgctgggt tcgacttatg cttggagtgt ttatcgtaac cctattattg
     5461 aaaaaacggg atgggatcag gcttctgttg ccttcgcctt tagtctagca atcttttgtt
     5521 tgggcttatc ggctgcattt atggggcgtt tggtagaaaa atttggtccg aaagtcatgg
     5581 ggagtctatc tgcttttcta tacgcaggtg gaaatatctt aacaggattt gcaatagacc
     5641 gtcaggaact gtggttgttg tatctagctt atggcatttt aggtgggctt ggtttgggag
     5701 caggctatat tacccctgtg tcaacgatta taaaatggtt tcctgataaa cgtggtctcg
     5761 caacaggttt agcgattatg gggtttggtt ttgcttcttt attgactagt cccatagcgc
     5821 aacacctcat cgcaggggta gggattgtag aaacttttta tattttagga gcaagttact
     5881 ttattatcat gctcctagct tcacaattca ttaagcgtcc aaatgagcaa gagcttgcaa
     5941 ttttatcttc ttcagggaaa gaaaaaacag cctctttgac gcaaggaatg gctgcaaatc
     6001 aggctctaaa aagcaatcgg ttttatatgc tttggattat tttctttatc aacatagctt
     6061 gtggtttagg cttaatttca gcggcatcgc caatggcaca ggagatggct ggcttgtcta
     6121 caagtcatgc agcagtaatg gtgggtgttt tggggatttt caatggattt ggtcgcttgc
     6181 tctgggcgag tttgtctgac tatatcggtc gccctctaac ctttagtata ttactgcttg
     6241 tcaatctttt cttttctctc tcactttggc tctttacaga ttccgtttta tttgtagttg
     6301 ctatgtctat tttgatgact tgctatggag ctggtttttc tttgattcca gcttatctca
     6361 gtgatatttt tggaaccaag gaattggccg ctctgcatgg ttatatttta acagcttggg
     6421 caatggctgg tttagcggga cctattttat tagcagagac ttataaaatg gctcattcgt
     6481 acacacaaac cttgttcgtt tttctcattt tatacagtat cgccttggct ttgtcttatt
     6541 atctaggtcg ttcaatcaaa aaagaaagtc aaaaaccgct tacatgattt tctgtagaaa
     6601 tggggctatc ttttgctctg gtcttgtgtt atactagata ggttgcaaag aaaacagtac
     6661 ttttcttttg tggaaaagaa gcaacacgat tttatatcta gttatatgaa aatacgtcat
     6721 aaaaagaaaa gtataaacta agccctatag ggtggcttcg caccaccttt agaaagaaga
     6781 ataacgtgaa atttaatgaa ttaaacttgt ctgctgattt gctagcagaa attgaaaaag
     6841 ctggttttgt agaagctagt cctatccaag aacaaactat tcctttggcc cttgaaggca
     6901 aggatgttat cggtcaagct cagactggta caggaaaaac tgcagccttt ggcttgccta
     6961 cccttgaaaa aatccgtata gaagaagcga ctattcaagc cttggtcatc gctccaactc
     7021 gtgaactagc tgtccaaagt caagaagaac tcttccgctt tggtcgtagt aagggagtca
     7081 aagtccgttc agtatatggc ggatcaagca ttgaaaaaca aattaaggct cttaaatctg
     7141 gtgcccatat cgtggtggga actccaggtc gcctcttgga cttgattaaa cgcaaggcct
     7201 tgaaattaca agacattgaa acccttatcc ttgacgaagc ggatgaaatg cttaacatgg
     7261 gcttccttga agacatcgaa gccattattt cccgtgtacc tgagaaccgt caaactttgc
     7321 ttttctcagc aactatgcca gatgccatca aacgtatcgg tgttcagttt atgaaagccc
     7381 ctgaacatgt caagattgcg gctaaggaat tgacaacaga attggttgac cagtactata
     7441 tccgtgttaa ggaacaagaa aaatttgaca ccatgactcg tctcatggat gtggcacaac
     7501 cagaactcgc tattgtattt ggtcgtacca aacgccgtgt ggatgaattg actcgtggtt
     7561 tgaaaattcg tggcttccgt gcagaaggaa ttcatggcga cctagaccaa aacaaacgtc
     7621 ttcgtgtcct tcgtgacttt aaaaatggca atcttgatgt tttggttgcg acagacgttg
     7681 cagcgcgtgg tttggatatt tcaggtgtga cccatgtcta caactacgat attccacaag
     7741 atcctgagag ttatgttcac cgtatcggtc gtacaggtcg tgctggtaag tcaggtcaat
     7801 ctattacttt tgttgctcca aacgaaatgg gttaccttca aatcattgaa aacttgacta
     7861 agaaacgcat gaaaggtctc aaacctgcaa gtgtagaaga atccttccaa tcaaaaaaac
     7921 aggtagctct caagaaaatc gaacgtgatt ttgcagatga aaccattcgt gccaactttg
     7981 agaaatttgg taaggatgct cgcaaattgg ctgctgagtt tactccagaa gaattggcaa
     8041 tgtatatctt gagtctgaca gtccaagacc cagatagcct tccagaagtg gagattgcac
     8101 gtgaaaaacc actaccgttt aaaccatcag gtaatggttt cggtggtaaa gctaagggag
     8161 gtcgtggagg ccgtcgtggg gacgaccgtc gagagcgtga tcgtcgtggc aatggtcgcc
     8221 gtgatgagtt caaaaaagga agtcgtggca acgatcgttt tgataaggaa aaacgttacc
     8281 gtaaggataa taaaaaacca cgcaatactt taagcgaaaa gcaaacaggc tttgttattc
     8341 gtaacaaagg tgataaataa gaaaaagcgg ttcaaaatga atcgcttttt tatataagga
     8401 gaccgaatgt gaaaaagaca aataaaatta ttatattatc ttttataata ttatgataca
     8461 caaaaatagg cgacttgtca atagaaaagg aacaatttaa ttaaaaatat tctggttttt
     8521 aattaaattg taagtcaatg caagtcaata aggaattttc agataattat tgaaaaagag
     8581 acgtttttat gttataatga tagcgattaa attcgaggtg aaaaatggca catttattag
     8641 aaaaaactag aaaaattaca tcaattttga aacgctcaga ggagcagttg caggatgagc
     8701 tcccttacaa cgctattacg cgtcagttag cggatattat tcattgcaat gcctgcatta
     8761 tcaatagtaa gggacgtctg cttggctatt ttatgcgtta taaaacaaat acagatcgcg
     8821 tagagcaatt cttccaaact aagattttcc cagatgacta cgttcaaggg gctaatatga
     8881 tttacgaaac agaagcaaac ttgcctgttg agcatgatat gagtattttc cctgttgaga
     8941 gtagagatga ttttccagat ggcttgacga ctattgcacc gattcatgta tcggggattc
     9001 gccttggttc tttgattatt tggcgtaatg ataaaaaatt cgaagatgag gacttggttc
     9061 ttgttgagat tgccagtacc gttgttggga ttcagcttct taacttccaa cgtgaagaag
     9121 atgagaaaaa tattcgtcgt cgtactgctg tcaccatggc ggtcaatacc ctttcttact
     9181 ccgaactccg tgctgtttca gcaattttag gggaattaaa tggaaatgaa gggaagttga
     9241 ctgcgtcagt gattgcagat cgtatcggaa tcactcgctc tgtgattgtc aatgctcttc
     9301 gtaaacttga gtctgcgggg attattgaaa gtcgctcact tggaatgaag ggaacctatc
     9361 ttaaggtctt gatttcagat atttttgaag aagtgaagaa aagagattac taatgacaaa
     9421 ggctttaatt tcgattgatt atacagaaga ttttgttgct gatagtggga agctgacagc
     9481 aggtgctcca gctcaggcga tttcggatgc catcagcaag gtaactcgat tagcttttga
     9541 acgaggagat tatatcttct ttactattga tgctcatgaa gaaaacgatt gtttccatcc
     9601 ggaaagtaag ttatttcctc ctcataatct gattgggacg agtggacgga atttatatgg
     9661 agatttgggg atcttttatc aagagcatgg ttcagacagt cgtgtctttt ggatggataa
     9721 acgccattac tcagcttttt cagggactga cctagatatt cgtttgagag agcgtagagt
     9781 gtctaccgtt atcttaacag gtgtcttgac ggatatctgt gtcctacata cagctataga
     9841 tgcctataat ctaggatatg acatcgagat tgttaaacca gctgttgctt ccatctggcc
     9901 tgaaaatcat caatttgccc taggtcattt caaaaataca ctcggagcta agttagtaga
     9961 tgaaaatcta aatgaacttt ctgagtaacc tggttggtga aaatgaaaaa atttgaaaaa
    10021 aagtgttgac aagcatccca aaagttgata tactagtaaa gtaatcgatg cggggatggc
    10081 ggaattggca gacgcgcagg actaaggatc ctgtgaccgc tttaggtcgt gagggttcaa
    10141 gtccctctct ccgcatagga aaagagttag ctaaagctag ctcttttgta tttctctaaa
    10201 aaattagaat ccagtcaaat gtagtggaga atcagcgaaa atatgggaaa actgatcctt
    10261 gtttctgctt ttgtcataga agaataataa agattatctt cttcaaattc tccgatattc
    10321 tctaaagttt tgtgcaagtt gcacagaact tttttatttt tttggtcatc ttgccataga
    10381 aatataaagc gttttcatct ataatataat tatcaaaaga caaaaggagt tcacctcatg
    10441 gtagaattga atcttaaaaa tatttacaaa aaatatccaa acagcgaaca ctattcagtt
    10501 gaagatttca acttgaacat caaagataaa gaatttatcg ttttcgtagg accttcagga
    10561 tgtggtaaat caactacact ccgtatgatt gctggtcttg aagacatcac agaaggtact
    10621 gcatctatcg atggcgtggt tgtcaacgac gtagctccaa aagaccgtga tatcgccatg
    10681 gtattccaaa actacgctct ttacccacac atgactgttt atgacaacat ggctttcggt
    10741 ttgaaattgc gtaaatacag caaagaagac attaacaaac gtgttcaaga agcagctgaa
    10801 atacttggat tgaaagaatt cttggaacgt aaaccggctg acctttcagg tggtcaacgt
    10861 caacgtgttg ccatggggcg tgcgattgtc cgtgatgcga aagtattctt gatggacgaa
    10921 cctttgtcaa acttggatgc caaacttcgt gtatcaatgc gtgctgaaat cgctaaaatt
    10981 caccgtcgta tcggagctac aactatctat gtaactcacg accaaacaga agcgatgaca
    11041 cttgcagacc gtatcgttat tatgtcagct actaagaacc ctgctggtac aggtactatc
    11101 ggacgtgtag aacaaatcgg tactcctcaa gaagtttaca aaaatccagt taacaaattc
    11161 gttgcaggat tcatcggaag cccagctatg aacttcatca acgtgaaatt ggttggtagc
    11221 gaaattgttt ctgacggttt ccgtttgaaa gtgccagaag gagcattgaa agttcttcgt
    11281 gaaaaaggct acgaaggaaa agaattgatc tttggtatcc gtccagaaga cgtgaatgca
    11341 gaacctgctt tccttgaaac attcccagac tgtgttgtaa aagcgactat ctctgtatca
    11401 gaactgcttg gttcagaatc tcacctttac tgccaagttg gtaaagacga gtttgttgca
    11461 aaagttgatg ctcgtgacta cttgcaaaca ggtgcaacag ttgagcttgg atttgacttg
    11521 aacaaagcac acttcttcga tgtagaaact gaaaaaacaa tctactaaga ataaataaaa
    11581 ttcaaagcac tacaagaaaa gatatctctt tatcaattgt agtggagaga tatcagttaa
    11641 tctagggaga gaaacaaaat gcttctctcc tttttgctag ggaagtcata ttatacatct
    11701 atattgtgat gctctttata ctcttcgaaa atctcttcaa accacgtcaa cgtcgccttg
    11761 ccgtacgtat gattactgac ttcgtcagtt ttatctgcaa cctcaaagct gtactttgag
    11821 tagcttacgg ctagtttcct agtttgctct ttgatttcca ttgagtatta tttgtgggta
    11881 ccatctacaa gtgaagctat atgcgtaaac tacgtgagca attgaattcg aactagagag
    11941 gtaataataa atttatgcta tagttatggt gacttgtatg cttttgattc tagtttatca
    12001 aataatagat tagaattgtc agataatatc attttgtgtt ataatgaaga aaaaacagag
    12061 gtgttcaaat gtcagaagca ggtcataagt ttttagcaaa attggggaaa aaacgcttac
    12121 gtccaggtgg aaagcgtgcc acagattggt taattgcaga aggaggattt tcaaaagaaa
    12181 agagaatact agaggttgcg tgtaataggg gaactacagc aattgagttg gcacagcgtt
    12241 ttggttgcaa gataactgct gttgatatgg atgctcaagc tttagaagtg gctaaaaaat
    12301 ctgctggaac ggcaggtgtt gctcatttaa tcagttttga aagagcaaat gcaatgaaac
    12361 ttccttatca agatgctagt tttgatattg ttataaatga agctatgctg actatgcaag
    12421 ccgatcaagc taagaaaaaa tgtgtaatgg aatatctaag ggtattaaaa cctggaggtc
    12481 ttctcttgac acatgatgtg cttcttaagg aagctaaaga gtctatcaga caggaattat
    12541 cacaagcaat tcatgtaaat gtaggtcctt taactcaaga tggttgggaa caggtgatga
    12601 tagaatcagg ttattgtgat gtgaaagcat tgactggtga aatgacatta atgaaattat
    12661 cgggtatgat ttatgacgaa ggtttgctag gaactttgaa aatttgtgta aatgcttgta
    12721 aaaaggagaa tagaaagcag tttttaacta tgtataaaat gtttgctaag aataaacaga
    12781 aattgggctt tattgcgatg gctagttata aatcgtcaaa acgttagata attattgaag
    12841 ttaacttttc cttttttctt tcttaaaaaa tatgctataa tagagagtaa aaaactttga
    12901 aagaaagaaa aaagatgaat ttaaaagatt acattgcaac aattgaaaat tatccaaagg
    12961 aaggcattac cttccgtgat attagtcctt tgatggctga tggaaatgct tatagctacg
    13021 ctgttcgtga aatcgttcag tatgctactg acaagaaagt cgacatgatc gtgggacctg
    13081 aagctcgtgg atttatcgtg ggttgtccag ttgcctttga gttgggaatt ggttttgcgc
    13141 ctgttcgtaa gccaggtaaa ttgccacgcg aagttatttc tgctgactat gaaaaagagt
    13201 acggtgtcga taccttgact atgcacgcgg atgccattaa gccaggtcaa cgtgttctta
    13261 ttgtagatga ccttttggcg acaggtggaa ctgttaaggc aactatcgag atgattgaaa
    13321 aacttggtgg tgttatggca ggttgtgcct tccttgttga attggatgaa ttgaacggcc
    13381 gtgaaaaaat cggtgactac gactacaaag ttcttatgca ttattaatga aaacagtccc
    13441 tagggctgtt ttctctacac taggatataa aaatagacta taactagtta gagaaaaact
    13501 ataattgaaa actatatctt cttgcagtat aataaaagga ctaagtgttt gagatttgtc
    13561 ttcaaacaca tgcaattatt cctgagagag tacagttagg agagggttat gccgattcga
    13621 attgataaaa aattgccagc tgttgagatt ttacggacag agaatatctt tgtcatggat
    13681 gatcaacgtg ctgcccacca agatatccgt cctttgaaga ttttaatttt aaatctcatg
    13741 ccacagaaaa tggtcacaga gacccagttg ttgcgccact tggctaatac acccctacaa
    13801 ctggatattg attttctcta tatggagagc caccgttcta aaacaactcg ttcagagcac
    13861 atggagacct tctataaaac ttttcctgaa gtcaaggatg agtattttga tgggatgatc
    13921 atcacgggtg ctccagttga gcatttacca tttgaggaag tggactattg ggaggaattt
    13981 agacagatgc ttgagtggtc taagactcat gtctattcga cccttcatat ctgttgggga
    14041 gctcaggctg ggctttatct gcgctatggt gtagaaaaat accagatgga cagtaagcta
    14101 tcaggtattt atcctcagga caccctaaaa gagggtcacc ttctatttag aggctttgat
    14161 gatagctatg tatcccctca ttcacggcac acggagattt ctaaggaaga ggtcttaaac
    14221 aagactaatc tcgagatttt atcagaagga cctcaggttg gggtttctat tttggccagt
    14281 cgtgatttac gagaaattta tagttttggt catttggagt atgaccgtga taccttggca
    14341 aaagagtatt ttcgagatcg tgatgcaggt ttcgacccac atattccaga aaattacttt
    14401 aaagatgatg atgttaatca ggtaccttgt ctttgttggt cttcatctgc agccctcttt
    14461 ttcagtaatt gggtaaacca tgcggtctat caggagacgc cttttgactg gagaaagata
    14521 gaagatgatg catctgcata tgggtattta taagaggaat tatgacatat ttagacgctt
    14581 ttaaatcagg taccttggtt ttaccgagtg ccctgctctt gcattttaag gaactctttc
    14641 cttctagcga cgattttctg gtttggcaat ttttctattt gcaaaatacg acaggcttag
    14701 aagaaatgtc gccaagccag attgctgaaa ggattggcaa ggaaatttcg gatgtcaacc
    14761 agtccatttc taatctgacg gaaaggggac tgctccagta tcgtactatc gaattaaatg
    14821 gcgaaattga attgctcttt gatgctagtt tggccttgga acgtttggat gacctgtttg
    14881 gagcagttca ttcaagttca gaccagctaa caccacaaaa ccagctcaag gatttggtgg
    14941 aaaccttcca gcaggagttg ggacgattgt tgacgccttt tgagattgag gatttgacca
    15001 agacactaaa ggaagatgga accagtgctg acttgattaa ggaggctctt cgtgaagctg
    15061 ttttgaatgg aaaaccaaac tggaagtaca ttcaggcgat tttgagaaac tggcgccatg
    15121 aaggaatcaa gagtgtggct caaattgagg ccaagagagc agaaagagaa gcaagcaatc
    15181 ctcagttgac acaggtatct gcagatttca gaaatgccat ggatctctgg aaggattaat
    15241 ccatgcaagt aggcttgaaa tccgagtaag atttgcaagc tgtgtataat tgtgatagaa
    15301 taaatagaaa ataaattgaa aaaagaggta tgtgaaatgt cacgtaaacc atttatcgct
    15361 ggtaactgga aaatgaacaa aaatccagaa gaagctaaag cattcgttga agcagttgca
    15421 tcaaaacttc cttcatcaga tcttgttgaa gcaggtatcg ctgctccagc tcttgatttg
    15481 acaactgttc ttgctgttgc aaaaggctca aaccttaaag ttgctgctca aaactgctac
    15541 tttgaaaatg caggtgcttt cactggtgaa actagcccac aagttttgaa agaaatcggt
    15601 actgactacg ttgttatcgg tcactcagaa cgccgtgact acttccatga aactgacgaa
    15661 gatatcaaca aaaaagcaaa agcaatcttt gcgaacggta tgcttccaat catctgttgt
    15721 ggtgaatcac ttgaaactta cgaagctggt aaagctgctg aattcgtagg tgctcaagta
    15781 tctgctgcat tggctggatt gactgctgaa caagttgctg cctcagttat cgcttatgag
    15841 ccaatctggg ctatcggtac tggtaaatca gcttcacaag acgatgcaca aaaaatgtgt
    15901 aaagttgttc gtgacgttgt agctgctgac tttggtcaag aagtcgcaga caaagttcgt
    15961 gttcaatacg gtggttctgt taaacctgaa aatgttgctt catacatggc ttgcccagac
    16021 gttgacggtg cccttgtagg tggtgcgtca cttgaagctg aaagcttctt agctttgctt
    16081 gactttgtaa aataatcagt aagtagcaaa agctaggtgg aacagcattc agatgtctgt
    16141 tacatttttt ataggagagc aaagattgaa aacaaaaatt ggattagcaa gtatctgttt
    16201 actaggcttg gcaactagtc atgtcgctgc aaatgaaact gaagtagcaa aaacttcgca
    16261 ggatacaacg acagcttcaa gtagttcaga gcaaaatcag tcttctaata aaacgcaaac
    16321 gagcgcagaa gtacagacta atgctgctgc ccactgggat ggggattatt atgtaaagga
    16381 tgatggttct aaagctcaaa gtgaatggat ttttgacaac tactataagg cttggtttta
    16441 tattaattca gatggtcgtt actcgcagaa tgaatggcat ggaaattact acctgaaatc
    16501 aggtggatat atggcccaaa acgagtggat ctatgacagt aattacaaga gttggtttta
    16561 tctcaagtca gatggggctt atgctcatca agaatggcaa ttgattggaa ataagtggta
    16621 ctacttcaag aagtggggtt acatggctaa aagccaatgg caaggaagtt atttcttgaa
    16681 tggtcaagga gctatgatgc aaaatgaatg gctctatgat ccagcctatt ctgcttattt
    16741 ttatctaaaa tccgatggaa cttatgctaa ccaagagtgg caaaaagtgg gcggcaaatg
    16801 gtactatttc aagaagtggg gctatatggc tcggaatgag tggcaaggca actactattt
    16861 gactggaagt ggtgctatgg cgactgacga agtgattatg gatggtgctc gctatatctt
    16921 tgcggcctct ggtgagctca aagaaaagaa agatttgaat gtcggctggg ttcacagaga
    16981 tggtaaacgc tatttcttta ataatagaga agaacaagtg ggaaccgaac atgctaagaa
    17041 aatcattgat attagtgagc acaatggtcg tatcaatgat tggaaaaagg ttattgatga
    17101 gaacgaggtg gatggtgtca ttgttcgtct aggttatagc ggtaaagaag acaaggaatt
    17161 ggcgcataac attaaggagt taaaccgtct gggaattcct tatggtgtct atctctatac
    17221 ctatgctgaa aatgagaccg atgctgagaa tgacgctaaa cagaccattg aacttataaa
    17281 gaaatacaat atgaacctgt cttaccctat ctattatgat gttgagaact gggaatatgt
    17341 aaataagagc aagagagctc caagtgatac agacacttgg gttaaaatca tcaacaagta
    17401 catggacacg atgaagcagg cgggttatca aaatgtgtat gtctatagct atcgtagttt
    17461 attacagacg cgtttaaaac acccagatat tttaaaacat gtaaactggg tagcggctta
    17521 tacgaatgct ttagaatggg aaaaccctta ttattcagga gaaaaaggtt ggcaatatac
    17581 ctcttctgaa tacatgaaag gaatccaagg gcgcgtagat gtcagcgttt ggtattaagc
    17641 gatgatttga aagagggatg tgatagtagc accctctttt tctttgtttt atgatagttc
    17701 atcctcgagt aaattcaaga tcttgctcgg aaatgaagct tatatagtag attgaatata
    17761 gacaaatacc ttgtgattgg taaaacattt tagaaattca tttacctttc ctaatcgact
    17821 tggtttcatc ttatttcaat ctattatagt attggggaat ttcttcaaac cacatcagct
    17881 tggtcagttc tacctgcgac ctcaaaactt gtgctttggt caagctgggt ttagtttcct
    17941 agtttgctga tggatttcca ttgactataa gcatccaacc ctctttttgt cttctaaaga
    18001 attcttaaat tatcagtcta ttgcaacttt tctcatgtgg gtcatttggc ttgcaattgt
    18061 ctttccttag tagtatactg aggtagtaat cattaagaag tggttacata aaaataatga
    18121 atgaggtaaa ataaaatggt agaattgaaa aaagaagcag caaaagatgt cgcaacatta
    18181 acaaaagcag cgccagtagc attggcaaaa acaaaggaag ttttgaatca agcagttgct
    18241 gatttgtatg tagctcacgt tgctttgcac caagtgcact ggtatatgca tggtcgtggt
    18301 ttccttgtat ggcatccaaa aatggatgag tacatggaag ctcttgatgg tcatttagat
    18361 gaaatcagcg aacgcttgat cacacttggt ggaagcccat tctctacttt gacagagttc
    18421 cttcaaaaca gtgaaatcga agaagaagct ggtgaatacc gtaatgttga agaaagcttg
    18481 gaacgtgttc tagctattta tcgctacctc atcactcttt tccaaaaagc gttggatgtg
    18541 actgacgaag aaggcgatga tgttacaaac gatatttttg ttggtgctaa ggctgaactt
    18601 gagaaaacag tttggatgct tgccgcagaa cttggacaag cacctggttt gtaagaaaca
    18661 agacaacata gataaatctg taggaaattt cttacagatt ttttctattt tgtaagctat
    18721 tccaaaccag tctttttttg agttttttga taaaatagta ctatcagtaa aaaggatgga
    18781 agcatgacta agaaaatcgt agctatttgg gcccaggatg aagatggtgt gattggtaag
    18841 gacaatcgtc tgccttggca tttaccagca gaattgcaac actttaaaga aacaactctg
    18901 aatcatgcta tcttgatggg gcgtgtgacc tttgatggaa tgggacgtcg tctgcttcca
    18961 aaacgggaga ccttgatttt gacacgtaat tcggaagaaa agctagacgg agttgctact
    19021 tttcatgatg tccagtctgt cttggactgg tatcatgctc aagacaagaa tctctatatt
    19081 cttggtggga agcaaatttt tcaggctttt gaaccctacc ttgatgaagt gattgtgact
    19141 cacattcatg ctcgggtgga gggagatacc tatttccctg aagagtttga cttgtccctt
    19201 tttgagacgg tttcaagcaa atcttatacc aaagatgaga aaaatcctta tgattttacc
    19261 atccaatacc gcaagagaaa ggaagtctaa tggaacggag tttatttggt ttattcacgg
    19321 cttttctgtg tttcatctgc cttttggcag gagcacaggc ttttcgtaaa aagcgttacg
    19381 ggctttctat cctcctttgg ttaaatgcct ttaccaatct ggtcaatagt attcatgctt
    19441 tttacatgac cttattttag atagaatgac agtatagaat ggaaggaaat catgtctaca
    19501 aatagaaaaa atgatatgat ggtttattgc tcattttgtg gcaaaagcca agaagaagta
    19561 caaaaaataa tcgctggcaa caatgccttt atttgtaatg aatgcgtgga gctagctcaa
    19621 gaaattattc gagaagaatt ggttgaggaa gtcttggcag acttgtctga ggtaccaaaa
    19681 ccaatcgaac tcctccatat cttgaaccac tatgtaatcg gtcaagatcg tgccaagcgt
    19741 gccttggcag tggcggttta taatcattac aaacgcatca atttccacga tacacgcgaa
    19801 gagtcagaag atgtggattt gcagaagtca aacatcttga tgattggccc aactggttca
    19861 gggaaaactt tccttgctca gaccttggct aagagcttga atgtaccttt tgcgattgcg
    19921 gatgcgacag ctctgacgga ggctggttat gtaggtgagg atgtggaaaa tatcctcctc
    19981 aaactcttgc aggctgctga ctttaacatt gagcgtgcag aacgtgggat tatctacgtg
    20041 gatgaaattg acaagattgc taaaaagagc gagaatgtat cgatcacacg tgatgtttct
    20101 ggtgaagggg tgcaacaagc cctcctcaag attatcgagg gaaccgtcgc aagcgtacct
    20161 cctcaaggtg gtcgcaagca tccacaacaa gagatgattc aagtggatac taaaaatatc
    20221 ctctttatcg tgggtggtgc ctttgatggc attgaagaaa tcgtcaaaca acgtcttgga
    20281 gaaaaagtca tcggatttgg tcaaaataac aaggcgattg atgaaaacag ctcttacatg
    20341 caagaaatca tcgcagagga tattcaaaaa tttggtatta tccctgagtt aattggacgc
    20401 ttgcctgttt ttgctgctct tgagcaattg acggtcgatg acttggttcg catcttgaaa
    20461 gagccaagaa atgccttggt caaacagtac caaaccttgc tttcttatga tgatgtcgag
    20521 ttggaatttg acgacgaagc cctacaagag attgctaata aagccatcga acggaagaca
    20581 ggggcgcgtg gacttcgctc tattatcgaa gaaacaatgc tagatgtcat gtttgaagta
    20641 ccgagtcagg aaaatgtgaa attggtccgc atcactaaag aagctgttga tggaacggat
    20701 aaaccaatcc tagaaacagc ctagaggtga ctatggaact gaatacacac aatgctgaaa
    20761 tcttgctcag tgcggctaat aagtcccact atccgcagga tgaactgcca gagatcgctc
    20821 ttgcagggcg ttcaaatgtt ggcaagtcta gctttatcaa taccatgctg aaccgtaaga
    20881 atctggctcg tacgtcaggg aaacccggga aaacccagct tctcaacttc tttaacattg
    20941 acgacaagat gcgctttgta gatgtgcctg gttatggtta tgcccgtgtt tccaaaaagg
    21001 aacgtgaaaa gtgggggcgc atgattgagg agtacctaac gactcgggaa aatctccgtg
    21061 cggtagtcag tttagttgac cttcgtcatg acccgtcagc agatgatgta cagatgtacg
    21121 aatttctcaa gtattatgag attccggtta ttatcgttgc gaccaaggcg gacaagattc
    21181 ctcgtggtaa atggaacaag cacgaatcag caatcaaaaa gaaattaaac tttgacccaa
    21241 gtgacgactt tatcctcttt tcatctgtca gcaaggcagg gatggatgag gcttgggatg
    21301 caatcttaga aaaattgtga ggaaaagaaa atggcaaaaa caattcatac agacaaggcc
    21361 ccaaaggcta tcggacccta tgttcaagga aaaatcgttg gcaacctttt gtttgctagc
    21421 ggtcaagttc ccctatcccc tgaaactggg gaaattgtag gagagaatat ccaagaacag
    21481 acagagcaag tcttgaaaaa catcggtgct attttggcag aagcaggaac agactttgac
    21541 catgttgtca aaacaacttg cttcttgagc gatatgaacg actttgttcc ttttaatgag
    21601 gtttaccaaa cggccttcaa agaggaattc ccagctcgtt cagctgtgga ggtagctcgt
    21661 cttcctcgtg atgtaaaagt cgaaattgaa gtcatcgcag agattggata agctagttga
    21721 agtttggtgt tgccaaactt cttttgatat aaggagaaaa agatgacaaa gaaacaactt
    21781 cacttggtga ttgtgacagg gatgagtggc gcagggaaaa ctgtagccat tcagtccttc
    21841 gaggatctag gttatttcac cattgataat atgccgccag ctctcttgcc taagtttttg
    21901 cagctggttg aaattaagga agacaatcct aagttggcct tggtagtgga tatgcgtagc
    21961 cgttctttct tttcagagat tcaagctgtt ttggatgagt tggaaaatca agatggtttg
    22021 gatttcaaaa tcctcttttt ggatgcggct gataaggaat tggtcgctcg ttacaaggaa
    22081 accagacgga gtcacccact agcagcagac ggtcgtattt tagatggaat caagttggaa
    22141 cgtgaactct tggcaccttt gaaaaatatg agccaaaatg tggtggatac gactgaactc
    22201 actccacgtg agctgcgtaa aacccttgca gagcagtttt cagaccaaga acaagcccag
    22261 tctttccgta tcgaagtcat gtctttcgga tttaaatatg gaatcccgat tgatgcggac
    22321 ttggtctttg atgtccgttt cttgccaaat ccctattatc taccagaact gagaaaccaa
    22381 acgggtgtgg atgaacctgt ttatgattat gtcatgaacc atcctgagtc agaagacttt
    22441 tatcaacatt tattggcctt gattgagccg attctgccaa gttaccaaaa ggaaggtaag
    22501 tccgttttga ccattgctat gggatgtacg ggtggacaac accgtagtgt ggcatttgct
    22561 aaacgcttgg tgcaggactt atccaagaat tggtctgtta atgaagggca tcgcgacaaa
    22621 gaccgcagaa aggaaacggt aaaccgttca tgagaaaacc aaagataacg gtgattggtg
    22681 gagggactgg aattcccgtc attctaaaaa gtctgcggga aaaagatgtg gaaatcgcag
    22741 ctatcgtgac ggtggcagat gatggtggtt cttcaggtga actccgaaaa aatatgcaac
    22801 agttgacacc gccaggtgat cttcgtaatg tccttgtggc catgtcggat atgcctaagt
    22861 tttatgagaa ggtctttcag tatcggttct ctgaggatgc cggagccttt gctggccatc
    22921 cattgggaaa tctcatcatt gctggcttgt cagaaatgca gggttcaacc tataatgcca
    22981 tgcagttatt gagcaaattt ttccatacaa cagggaaaat ttatccttcc agtgaccatc
    23041 ctttgaccct tcatgcagtc tttcaggatg ggacagaagt ggctggagag agtcatattg
    23101 tagaccatcg aggcataatt gacaatgtct atgtgaccaa tgccctaaac gatgatacgc
    23161 ctctggccag ccgtcgagta gtgcagacca tccttgaaag tgacatgatt gtcctagggc
    23221 caggttccct ctttacctct attttgccca atatcgtgat taaggaaatt gggcgggctc
    23281 ttttggaaac taaggcagaa attgcctatg tctgcaatat catgacccaa cgtggggaga
    23341 cggaacactt tacagatagc gaccacgtgg aagtcttgca tcgtcacctt ggtcgccctt
    23401 ttatcgacac tgtcttggtg aatattgaaa aagtgcctca ggaatacatg aattccaacc
    23461 gttttgatga atacttagtg caagtggaac acgattttgt aggtctttgt aagcaagttt
    23521 cgcgcgtgat ttcatctaac ttccttcgtc tggaaaatgg cggtgccttc cacgatggag
    23581 atttgattgt ggacgagttg atgcgcatta tacaggtgaa aaaatgagtt tcacagtagc
    23641 agtaaaagaa gaaatcctgg gccaacacca tctgagccgg catgaattat ctgccattat
    23701 caaaatgtct ggtagcatcg gtctctcgac ttcgggcttg actttgtcag ttgtgacaga
    23761 aaatgccaaa ctggcccgtc acctctatga gtcctttctc catttctatg aaatcaaatc
    23821 tgaaattcgt caccaccaac ggagcaatct tcgcaagaat cgcgtctata ccgtttttac
    23881 agatgaaaag gtgcaggatt tgttaagtga tttgcacttg gcagactctt tctttggcct
    23941 ggaaacaggt attgatgagg cgattttatc ggacgaggaa gcaggtcgtg cctatctctg
    24001 tggcgctttc ttggcaaatg ggagcattcg tgaccctgag tcaggcaagt accagttgga
    24061 aatcagttct gtttatctgg accacgcgca aggaattgcc tcccttctcc aacagttttt
    24121 actggatgcc aaggtgcttg agcgcaagaa gggggctgtg acctatctcc agcgagcaga
    24181 agacattatg gacttcttga tagtaatagg agccatgcag gcacgtgatg attttgagcg
    24241 ggttaagatt ttgcgagaaa cccgtaacga cctcaatcgg gctaataatg ccgagacagc
    24301 taatatcgct cggacagttt ctgccagcat gaagaccatt aacaatatca gtaaaatcaa
    24361 agatatcatg ggcttagaaa atttgccagt agatttgcag gaagtggcgc aactgaggat
    24421 tcagcaccca gactactcta tccagcagtt agcagatagt ctcagcaccc ctctgaccaa
    24481 aagtggtgtc aatcacagac tcagaaaaat caataagata gcggatgaat tataaaacca
    24541 cgaatcctat gtgactcgtg gttctttttt ataaactggt agagtgtttt ggttgtactt
    24601 tttgttcagg gtcaatgtag ttgatagcgt tgttgacagc agttggagct tctccgaggc
    24661 ctgtcgcaat cagatcaatt tttccgtcat agtagcagca gtcaccgata gcatagatac
    24721 ctgcttggct ggattcctgt ttgctgttga cgataatctt gtgacggttg aggtcgagcc
    24781 cccagttttt aaggttaccg acagaagatt tgaaaccata gttgacaaag aggtggtcta
    24841 ggtcaatggt ttcagtttca tcagatttga cttttgtgat ttcaagttta tcaagtgttt
    24901 ttccatttcc aaggagttgg ctaggggcga atggtgtctt gatggttaca gatgattctt
    24961 gcaaggtttg aacactgtgt tccaaggcac ggaaattatc tctgcggtga acaagggtag
    25021 ttggtgcgat tttttcaaaa gccaaagccc aatccacagc cgagtctccc ccaccaagaa
    25081 tcgtcacttt cttaccagcg tattgctgaa tgttagaaac gtggtagtgg atattttcat
    25141 agtcctcaac cccttcaagt tccagcggac gtggtttgaa ggcaccgcca cccatagcga
    25201 tgataactgt tttagtcagg tgacttcctt tggaagttgt gatggcaaat tcttcttctt
    25261 gtttgtcaat ctcaagaacc gtttcattga gatgaatagg ggtatcaaat ccatttagct
    25321 gttcaatcaa gcggttagtc aactcttctc cagtcaggtt tgggaagcct ggtacgtcta
    25381 ggatttcctt ttcagggtag agaatagcag gttgtccacc tagctgggga agagagtcga
    25441 tgatttgaac cttggcttgg cgtaggtggg cataaaaggc tgcaaaaagc ccgacaggac
    25501 caccacccac aatggtaata tcatagagtt gagacatagt ttctcctttg ttttttctag
    25561 tcagtttatt ttatcatatt tttgttcaat gtaaaatgga ctaggatagg gaaaaaaatg
    25621 ccagaaaatg gtataatagg acgaaagtgt tttgataggg aggatatcag ggatgaattt
    25681 tcaacaatta tccaatctgc aatattggac cagtttgttt gcaagtccat ggacgatagc
    25741 tatcaatctg attgatattt tgattgttgc ttatatttta taccatttta caaaagctat
    25801 tgcaggaacc aagattatga ttttggtacg tggagttttg gtgtttattt tagctcaaat
    25861 ccttgcaaat atgattggtt tgactacgat ttcttggtta atcaatcaaa ttattactta
    25921 tggggttatt gcggcggttg ttatcttctc tccagagatt cggactggtt tggaacgttt
    25981 gggaagagcg acagatttct tttccaatgc ccctattagt gctgaggaac agatgattcg
    26041 tgcctttgtt aagtctgttg aatacatgag tcctcgtaaa atcggggcct tggttgctat
    26101 tcagcgtgta cgtaccttgc aggagtatat gtcgacagga attcccttgg atgctaagat
    26161 ttctgcagaa cttctcatta acatttttat tcccaacact cccctacatg acggtgcggt
    26221 gattatcaaa gaagaacgta tcgctgtgac gtctgcctat ctgcccttga caaaaaacac
    26281 agggatttcc aaggaatttg ggaccagaca ccgggcggct atcggtttat cagaagtctc
    26341 agatgccttg acttttgtcg tatcagagga aacgggagga atttcgataa cctataatgg
    26401 aaggtttaag cacaacctaa cacttgatga atttgaaaca gaattacgtg aaatcttact
    26461 tccaaaagag gaagtgggtc ttagttttaa agaacgattg ctaggaggat ggaaacatga
    26521 aaaaaaatag tttatatatc atatcctcac tcttttttgc ttgtgtctta tttgtctatg
    26581 ctacggcgac gaattttcaa aacagtacca gtgctaggca ggtaaaaacg gaaacctata
    26641 ctaatacagt aaccaatgtc cctattgaca tacgctataa tagtgataag tattttatta
    26701 gcggttttgc ttcagaagta tcagtggtct tgactggtgc aaatcgccta tcgctagcta
    26761 gtgaaatgca agaaagtaca cgtaaattca aggttactgc tgacctaaca gatgccggtg
    26821 ttggaacgat tgaagttcct ttgagcattg aagatttacc caatgggctg accgctgtgg
    26881 cgactccgca aaaaattaca gtcaagattg gtaagaaggc tcagaaggat aaggtaaaga
    26941 ttgtaccaga gattgaccct agtcaaattg atagtcgggt acaaattgaa aatgtcatgg
    27001 tgtcagataa agaagtgtcg attacgagtg accaagagac attggataga attgataaga
    27061 ttatcgctgt cttgccaact agcgaacgca taacaggtaa ttacagtggt tcagtacctt
    27121 tgcaggcaat cgatcgcaat ggtgttgtct taccggcagt tatcactccg tttgatacaa
    27181 taatgaaggt gactacaaaa ccagtagcac caagttcaag cacatcaaat tcaagtacaa
    27241 gcagttcatc ggagacatct tcgtcaacga aagcaactag ttcaaaaacg aattaaaaat
    27301 agaaaaggat tttataacaa tgggtaaata ttttgggact gatggagtcc gtggagaagc
    27361 taacctagag ctaacaccag aattagcctt taaactagga cgttttggag gctatgttct
    27421 tagtcaacat gaaacggaag cgccgaaagt ctttgtagga cgtgacacac gtatttcagg
    27481 ggaaatgctg gaatcggcct tggtggcagg tctcctttca gtagggattc acgtatacaa
    27541 acttggtgtc cttgcaacac cagcagtagc ttacttggtt gaaactgaag gagcaagtgc
    27601 cggtgtcatg atttctgcta gccacaaccc agcccttgat aacggaatca agttctttgg
    27661 cggtgatggc ttcaaactag atgatgaaaa agaagcagaa attgaagcct tgctagatgc
    27721 tgaggaagac actcttcctc gtccaagtgc agaaggctta ggaattttgg tagattatcc
    27781 agaaggcttg cgtaagtatg aaggatacct tgtttcaact ggaactcctc ttgatggaat
    27841 gaaggttgcc ttggatacag ctaatggagc agcttctacc agtgcccgtc aaatctttgc
    27901 agaccttggt gcccaattga cggttatcgg ggaaacacca gacggtctta acatcaacct
    27961 taatgttggt tcaacacatc cagaagccct tcaagaaatg gtcaaagaaa gtgggtcagc
    28021 tattggtttg gcctttgatg gagacagtga ccgcttgatt gctgttgatg agaatggtga
    28081 catcgtcgat ggtgacaaga ttatgtacat catcggaaaa tacctttctg aaaaaggaca
    28141 attggctcaa aatacaattg tgacaactgt tatgtctaac cttggtttcc acaaggcctt
    28201 gaatcgcgaa ggtattaaca aggcagttac tgcagttggt gaccgctacg ttgttgaaga
    28261 aatgagaaaa tcaggctaca accttggtgg tgaacagtct ggtcacgtta tcttgatgga
    28321 ttacaatacc acaggtgatg gtcaattatc agcagttcaa ttgactaaaa ttatgaagga
    28381 aactggtaag agcttatcag agttggcggc agaagtaacg atttatccac aaaaattagt
    28441 taatatccga gtggaaaacg ccatgaagga aaaggccatg gaagtgccag ctatcaaggc
    28501 catcatcgag aagatggaag aagaaatggc ggggaacggc cgtatccttg ttcgtccaag
    28561 tggaacagag cccctcttgc gtgttatggc agaagcgcct acaacagaag aagtggacta
    28621 ctatgttgat actatcacag atgtagttcg tgctgaaatt gggattgact aaatcctaga
    28681 aaactagatg aaaataaaaa attatggtac aatagcttat aatattgtag ccgatggaga
    28741 aagacatgaa tcttaaacgt gaacaagaat ttgttagtca gtatcatttt gatgcgcgta
    28801 attttgaatg ggaaaatgaa aatggagctc ctgaaaccaa ggtggatgtg aatttccaat
    28861 tgctccaaca tgaccaagaa aatcaagtga cttccttgat tgtcatcttg agctttatga
    28921 ttgtatttga taagtttgtc attagtggaa caatctcaca agtaaaccat atcgatggcc
    28981 gtattgtcaa tgaaccaagt gaattgaacc aagaagaggt ggaaaccttg gctcgtccat
    29041 gtttgaacat gctcaatcgt ttgacttacg aagtgactga aattgcatta gacttaccag
    29101 gaattaattt ggagttctaa tatgaaatta gctgttttca cagattcctc tgcttatctc
    29161 agtgaagaga ccttgcaaag agaagacttg tttgtcttgg atattcctgt caatattgat
    29221 ggtgaggaat atgtcgaagg catcaatctg tctgctgagg aattttacca aaaaatggct
    29281 caggcttctg aattgcctaa gaccagtcaa ccaagtattg ccaagttaga tgaaatctta
    29341 acttcgctca aagaacaagg ctatacacat gccttggggc ttttcctatc ttctggaatt
    29401 tcaggttttt accaaaatat ccagtatatg gtcgatgact atgagggctt aaccattgct
    29461 ttcccagaca ctttgattac aagtgctccc ctaggcatca tggttgaaag cgtctttaat
    29521 tggcgtgatc agggcgatga ttttgccagc attcaggata agctagccat tcaaatcagc
    29581 cgtacgtcag cctttatcat ggtagatgac ttggatcatt tggtaaaagg tggacgcctt
    29641 tcaaatgggg ctgccatttt gggcaatttg cttagcatta agccaatcct ttattttaac
    29701 gatcaaggtg tgattgaagt ttacgaaaaa gttcgtactg aaaagaaggc caccaaacgc
    29761 ttaattgaaa ttatcaagga aacaacggct tcaggtcaat accgggtcat tgtcattcat
    29821 gggaatgctc ctgaaaaggc tgaagaattg cgtcagcatt tgcttgattt tggcttgggt
    29881 tcggatgttt cacttgctac atttggtagt gtcattggaa cgcacctagg agcaggaagt
    29941 attgctctgg gttatattcc agtgatttag ttggcacttc taggctagtt aatcttagaa
    30001 attgaacacg gactacctgc ctcttgaaaa aagatgcctg tcttgccttt cgtggaaagt
    30061 cagtgccatt ccctattttt caggggcagc taaggtcctt tgtatcttga taattgaaca
    30121 cgcctggaac cctgtgtgaa aaagatagtt cttccaagaa gtagacactt cttgattgga
    30181 attcctattt tcactttgtg ttcttacgga ctttgtatct tagacaggag tagagatgag
    30241 tattcgagta attattgccg gttttaaggg aaagatgggc caggctgctt gtcagatggt
    30301 attgactgat ccagacttgg acttggtggc agttttggat ccttttgagt ctgagtcaga
    30361 atggcagggt attcctgttt tcaaggataa ggctgattta gctggttttg aagcggatgt
    30421 ctgggtagat tttactactc cagctgttgc ctacgaaaat acacgttttg ctcttgaaaa
    30481 tggctttgct ccagtagttg gaacgactgg tttcacgagt gaagaaattg cagagctaaa
    30541 agaattttct cgtgcccaag acttgggtgg cctgattgcc cctaactttg ccttgggtgc
    30601 tgtcttactc atgcaatttg cgacgcaggc tgccaaatat ttcccaaatg tggagattat
    30661 tgagctccat catgacaaga aaaaggatgc tccgagtgga acagccatta aaacagctga
    30721 gttgatggca gaggttcgag agtccattca gcaaggtgca gcagatgagg aagagctgat
    30781 tgctggtgct cgtggtgctg actttgatgg tatgcgcatc cactcagttc gtttgccagg
    30841 cttggtagct catcaggaag tcatctttgg caatcaggga gaagggttga ccctccgtca
    30901 tgactcctat gatcgcatct ccttcatgac aggagtcaat ttgggaatta aagaagttgt
    30961 caagcgtcat gagcttgtct atggattaga acacttatta tgagattaat gcaaatgcct
    31021 tctgaatttc agaaggcttt accagtatta gaaaaaatta aagaagcagg ctttgaggct
    31081 tattttgttg ggggctctgt tcgagatgcc cttctccata gccctatcca cgatgtggat
    31141 attgcgacgt cttcttatcc agaagagacc aagcagattt ttccgcgaac agccgatatc
    31201 ggaatcgagc atggaaccgt cttggtctta gatggggatg aggagtatga ggtaacaacc
    31261 tttcggacag aggatgtcta tgtggactat cgcagaccca gtgcggtttc ctttgtgcgc
    31321 tcgctagaag aagacctcaa acgccgtgat ttcacagtca acgcctttgc cttggatgag
    31381 acaggagaaa tcgttgactt gttccatggt ttagaagatt tggaaaagca agtcttgcga
    31441 gcagttggag tggctagtga gcgtttcaac gaagatgctt tacggattat gcgtggtttc
    31501 cgttttcagg ctagtcttgg ttttgcactt gagccagaaa catttaaagc tatgaagacc
    31561 ttgacgccgc ttttggagaa aatttctgta gagcgtacct tcgtcgagtt tgataaactc
    31621 ttgctggctc cattttggag aaggggcttg gcttccatga ttgagagtca agcttatgac
    31681 tatctccctg atatggcatc tagccaggac aagctcaaca gactgtttga tttggagact
    31741 gattttactt ttgaatcctc tgaacaagcc tgggcggctt tactatgggc tttggagatt
    31801 gaaaatgcgc agtcattttt gaaatcttgg aagacctcac gccagtttgc caagcaagtt
    31861 caggatttgc tgattatttt ggctctgcgt gaaaatggag aattgagtaa gcgtgattgt
    31921 tatcgctttg acttggattt acttttacag gctgaaaatc ttcgtcaagc tcagggaaaa
    31981 gaagtcaacc cacaagtcat taaagaaacc taccagagct tgactattca tgataagaaa
    32041 gaaatccaaa tcaacggcgg tattttgatc aaggaatatg gctatcagcc aggcccagac
    32101 ttgggagaga ttttaacaga gattgagttt gccattgtcg atggagaatt ggagaataat
    32161 cgtgaagcca tccatgctta cctgagggag aaaaaatgag tgattttatc gttgaaaaac
    32221 taagtaaatc cgttggtgac aagaccgttt ttagggatat ttcctttatt atccatgact
    32281 tagacagaat tggtttaatc ggtgtcaatg ggactggcaa gaccaccctt ttggacgtcc
    32341 tttctggtgt ttctggattt gatggggatg tcagtccttt ttcagctaaa aatgattacc
    32401 agattggtta cttgactcag gatcctgatt ttgatgatag aaagacagtt ttggatacgg
    32461 ttctatctag tgaactcaag gaaatccagc tcattcgtga gtatgaattg attatgctcg
    32521 actatagtga ggacaagcag gcgcgtttgg aacgtgtcat ggcagagatg gactctctcc
    32581 aagcttggga aattgagagt caggtcaaga ccgttcttag caaattgggc attcaagact
    32641 tatctactcc tgttggggaa ttgtcaggtg gtctgagaag acgggtacag ttggcacaag
    32701 tcttacttgg caaccacgac cttttgcttt tggatgagcc gaccaaccat ctggatattg
    32761 cgattattga gtggctgacc ctctttttga aaaattctaa gaagaccgtc ctttttatca
    32821 ctcacgatcg ttatttctta gacgctttgt caacacggat tttcgagttg gagcgagcag
    32881 gcttgacaga atatcagggc aattaccagg actatgttcg ccttaaggca gaacaggacg
    32941 agcgcgatgc agctctactt cataaaaaag aacaactcta caaacaagaa ctggcctgga
    33001 tgcgcagaca accgcaggca cgtgcgacca agcaacaagc tcgtatcaat cgtttccatg
    33061 atctgaaaaa ggaagtttca ggcagtagtg ctgagacaga cttgactatg aactttgaaa
    33121 ccagtcggat tgggaagaaa gtcatcgagt ttcaggatgt ttcctttgcc tatgaaaata
    33181 agcccatttt gcaaaatttt aatctcttag ttcaggctca agaccgtatt ggaattgttg
    33241 gggacaatgg tgttggaaaa tcaaccctac ttaacctgat tgcaggaagt cttgagccga
    33301 cagcaggaca agttgtgatt ggggaaactg ttcgcatcgc ctatttctct caacaaattg
    33361 agggtttgga tgaaagcaag cgtgtgatca attacctgca ggaagtggca gaggaggtca
    33421 agaccagtgg tggttctacg acttccatcg ctgagttgct ggagcaattc ctcttcccac
    33481 gttcgacgca tgggactttg attgagaaat tgtcaggggg tgagaaaaaa cgtctttatc
    33541 tcctcaaact gcttttggaa aaaccaaatg ttcttctttt agacgagcca accaatgacc
    33601 tagatattgc aactttgaca gtcttagaga atttcttgca aggttttgca ggtcccgttt
    33661 taacagtcag tcacgaccgc tatttcttgg ataaggtagc gaccaagatt ctcgcttttg
    33721 aggatggcaa gattcgtcct ttctttggtc attacaccga ctatcttgat gaaaaagctt
    33781 ttgaaacaga tatggccaat caagtgcaaa aggccgaaaa ggaaaaagtg gtcaaggttc
    33841 gagaagacaa gaaacgcatg acctaccaag aaaagcagga gtgggcaagt attgaaggtg
    33901 ata
//
LOCUS       DAVHTH010000019        33168 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.019, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000019 DAVHTH010000000
VERSION     DAVHTH010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33168)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33168)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33168
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.019"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            complement(<1..155)
                     /locus_tag="VVR63_000936"
     CDS             complement(<1..155)
                     /locus_tag="VVR63_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU6128965.1"
                     /translation="MIQPLLHADETSYRVLENDSHLTYYWTFLSGKAENQAITLYHHD
                     QRRSGSVV"
     gene            complement(164..469)
                     /locus_tag="VVR63_000937"
     CDS             complement(164..469)
                     /locus_tag="VVR63_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000484483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase zinc-finger binding
                     domain-containing protein"
                     /protein_id="HEU6128966.1"
                     /translation="MFPVETEEITYKRKKSKGKRQAILAQFDSEEVHHQVEESICPDC
                     QDDLKEIGASLQRQELVFIPAQLKRVDHIQHAYKCQTCSKNNPSDKIVKAPIPKAPL"
     gene            complement(456..650)
                     /locus_tag="VVR63_000938"
     CDS             complement(456..650)
                     /locus_tag="VVR63_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU6128967.1"
                     /translation="MKIIQQQSAIIDSLTNELSLLCEQVAYLTQKLSGKSSEKSVCPF
                     GQLNLFEEESPSEKDGDVPS"
     gene            complement(820..1170)
                     /gene="tnpB"
                     /locus_tag="VVR63_000939"
     CDS             complement(820..1170)
                     /gene="tnpB"
                     /locus_tag="VVR63_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HEU6128968.1"
                     /translation="MTIHLSSLGQVYLVCGKTDMRQGIDSLAYLVKTHFELDPFSGQV
                     FLFCGGRKDRFKALYWDGQGFWLLYKRFENGRLTWPSTEKDVKALTPEQVDWLMKGFS
                     ITPKINLSESRDFY"
     gene            complement(1151..1336)
                     /locus_tag="VVR63_000940"
     CDS             complement(1151..1336)
                     /locus_tag="VVR63_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6128969.1"
                     /translation="MPQPIVPVEIPQSRPFDSKKRNDILLKIRIGKLEVSFFQSLNLE
                     MVEQLLDKVLLYDNSSI"
     gene            complement(1640..3202)
                     /gene="guaA"
                     /locus_tag="VVR63_000941"
     CDS             complement(1640..3202)
                     /gene="guaA"
                     /locus_tag="VVR63_000941"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HEU6128970.1"
                     /translation="MSNISTDLQDVEKIIVLDYGSQYNQLISRRIREIGVFSELKSHK
                     ISAAEVREVNPVGIILSGGPNSVYEDGSFDIDPEIFELGIPILGICYGMQLLTHKLGG
                     KVVPAGDAGNREYGQSTLTHTPSALFESTPDEQTVLMSHGDAVTEIPADFVRTGTSAD
                     CLYAAIENPDKHIYGIQFHPEVRHSVYGNDILRNFALNICKAKGDWSMDNFIDMQIKK
                     IRETVGDKRVLLGLSGGVDSSVVGVLLQKAIGDQLICIFVDHGLLRKGEADQVMDMLG
                     GKFGLNIVKADAAKRFLDKLAGVSDPEQKRKIIGNEFVYVFDDEASKLKDVKFLAQGT
                     LYTDVIESGTDTAQTIKSHHNVGGLPEDMQFELIEPLNTLYKDEVRALGTELGMPDHI
                     VWRQPFPGPGLAIRVMGEITEEKLETVRESDAILREEIAKAGLDRDIWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAKIPWEVLQKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            3344..4042
                     /locus_tag="VVR63_000942"
     CDS             3344..4042
                     /locus_tag="VVR63_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEU6128971.1"
                     /translation="MLPAYMKIHDQIKKDIDEHRWAIGERLPSERDLAEQFAVSRMTL
                     RQAVSLLVEEGVLERRVGSGTFVSSTRVQEKMRGTTSFTEIVKSQGKVPSSQLISYKK
                     TIPNEQEVAKLGIFPTDNIIRMERVRYADQVPLVYEVASIPEKFIKDFKKEEITSHFF
                     QTLQKHGYRIGKSQQTIYARLAKEKIAHYLEVEKGHAILGLTQVSYLEDGTAFEYVKS
                     QYVGERFEFYLENN"
     gene            complement(4085..4981)
                     /locus_tag="VVR63_000943"
     CDS             complement(4085..4981)
                     /locus_tag="VVR63_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEU6128972.1"
                     /translation="MSNSLKGTLLTVVAGIAWGLSGTSGQYLMAHGISALVLTNLRLL
                     IAGGILMLLAYATAKDKILVFLKDRKSLLSLLIFALIGLFLNQFAYLSAIQETNAGTA
                     TVLQYVCPVGILIYSCIKDRVAPTLGEIVSIIFAIGGTFLIATHGQLDQLSMTPAGLF
                     WGLFSALTYALYIILPIALIKKWGSSLVIGVGMVIAGLVALPFTGVLQADIPTSLDFL
                     LAFAGIILIGTVFAYTAFLKGASLIGPVKSSLLASIEPISAVFFAFLIMNEQFYPIDF
                     IGMAMILFAVTLISLKDLFLEK"
     gene            complement(4990..5925)
                     /locus_tag="VVR63_000944"
     CDS             complement(4990..5925)
                     /locus_tag="VVR63_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HEU6128973.1"
                     /translation="MKWTKIIKKIEEQIEAGIYPGASFAYFKDNQWTEFYLGQSDPEH
                     GLQTEAGLVYDLASVSKVVGVGTVCTFLWEIGQLDIDRLVIDFLPESDYPDITIRQLL
                     THATDLDPFIPNRDLLTAPELKEAMFHLNRRSQPAFLYSDVHFLLLGFILERIFNQDL
                     DVILKDQVWKPWGMTETKFGPVELAVPTVRGVEAGIVHDPKARLLGRHAGSAGLFSTI
                     KDLQIFLEHYLADDFARDLNQNFSPLDDKERSLAWNLEGDWLDHTGYTGTFIMWNRQK
                     QEATIFLSNRTYEKDERAQWILDRNQVMNLIRKEE"
     gene            complement(5922..6647)
                     /locus_tag="VVR63_000945"
     CDS             complement(5922..6647)
                     /locus_tag="VVR63_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HEU6128974.1"
                     /translation="MNVNQIVRIIPTLKANNRKLNETFYIETLGMKALLEESAFLSLG
                     DQTGLEKLVLEEAPSMRTRKVEGRKKLARLIVKVENPLEIEGILSKTDSIHRLYKGQN
                     GYAFEIFSPEDDLILIHAEDDIASLVEVGEKPEFQTDLASISLSKFEISMELHLPTDI
                     ESFLESSEIGASLDFIPAQGQDLTVDNTVTWDLSMLKFLVNELDIASLRQKFESTEYF
                     IPKSEKFFLCKDRNNVELWFEEV"
     gene            complement(6731..7366)
                     /locus_tag="VVR63_000946"
     CDS             complement(6731..7366)
                     /locus_tag="VVR63_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-alkyl-2-acetylglycerophosphocholine esterase"
                     /protein_id="HEU6128975.1"
                     /translation="MAVQLLENWLLKEQEKIQTKYRHLNHISVVEPNILFIGDSIVEY
                     YPLQELFGTSKTIVNRGIRGYQTGLLLENLDAHLYGGAVDKIFLLIGTNDIGKDVPVN
                     EALNNLEAIIQSVARDYPLTEIKLLSILPVNEREEYQQAVYIRSNEKIQNWNQAYQEL
                     ASAYMQVEFVPVFDCLTDQAGQLKKEYTTDGLHLSIAGYQALSKSLKDYLY"
     gene            complement(7368..8195)
                     /locus_tag="VVR63_000947"
     CDS             complement(7368..8195)
                     /locus_tag="VVR63_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU6128976.1"
                     /translation="MMIKVIATDMDGTLLDARGQLDLPRLEKILDQLDQRGIRFVIAT
                     GNEIHRMRQLLSPLVDRVVLVVANGARIFENNELIQAQTWDDAIVNKALTHFKGRACQ
                     DQFVVTGMKGDFVKEGTIFTDLESFMTPEMIEKFYQRMQFVDELTSDLFGGVLKMSMV
                     VGEERLSSVLEEINALFDGRVRAVSSGYGCIDILQAGIHKAWGLEELLKRWDLKSQEI
                     MAFGDSENDVEMLEMAGIAYAMENADEKAKAVATALAPANSQGGVYQVLENWLEKGE"
     gene            complement(8217..8552)
                     /locus_tag="VVR63_000948"
     CDS             complement(8217..8552)
                     /locus_tag="VVR63_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="poly-gamma-glutamate biosynthesis protein"
                     /protein_id="HEU6128977.1"
                     /translation="MGNFISNQRIESMGDEENAKWTERGVLMDVTIKKKDGKTTIGTA
                     KAHPTWVNRTPKGTFSPEGYPLYHYQTYILEDFIEDGSHRDQLDEATKERIDTAYKEM
                     NEHVGLKWY"
     gene            complement(8553..9269)
                     /locus_tag="VVR63_000949"
     CDS             complement(8553..9269)
                     /locus_tag="VVR63_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HEU6128978.1"
                     /translation="MAHGDLLYHDGLFFSAKKEDGTYDFHENFEYVTPWLKQADLAIG
                     DFEGTINKDHYLAGYLLFNAPVEVMDAIKEAGYHVLDLAHNHILDSQIEGVISMADII
                     EKAGITPIGVYTHEPRAQAPLVIKEVNAIKVALLAYSYGFNGIEQYISQEDYNRYLSD
                     LNEDKIKAEVERAEKEADITIIMPQMGVEYRLEPTEEQKALYHKMIDWGADIIFGGHP
                     HVVEPSETVEKDGDKKLIVY"
     gene            9782..10393
                     /locus_tag="VVR63_000950"
     CDS             9782..10393
                     /locus_tag="VVR63_000950"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEU6128979.1"
                     /translation="MSAIERITKAAHLIDMNDIIREGNPTLRTVAEEVTFPLSDQEII
                     LGEKMMQFLKHSQDPVMAEKMGLRGGVGLAAPQLDISKRIIAVLVPNIVEEGETPQEA
                     YDLEAIMYNPKIVSHSVQDAALGEGEGCLSVDRNVPGYVVRHARVTVDYFDKDGEKHR
                     IKLKGYNSIVVQHEIDHINGIMFYDRINEKDPFAVKDGLLILE"
     gene            10438..11166
                     /gene="rlmB"
                     /locus_tag="VVR63_000951"
     CDS             10438..11166
                     /gene="rlmB"
                     /locus_tag="VVR63_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HEU6128980.1"
                     /translation="MKTNDIVYGVHAVTEALLANTGNKLYLQEDLRGKNVEKVKELAT
                     EKKVSISWTSKKSLSEITEGAVHQGFVLRVSEFAYSELDYILAKTRQEENPLLLILDG
                     LTDPHNLGSILRTADATNVSGVIIPKHRTVGVTPVVAKTATGAIEHVPIARVTNLSQT
                     LDKLKDEGFWTFGTDMNGTPCHKWNTKGKIALIIGNEGKGISSNIKKQVDEMITIPMN
                     GHVQSLNASVAAAILMYEVFRNRL"
     gene            complement(11205..12116)
                     /gene="trxB"
                     /locus_tag="VVR63_000952"
     CDS             complement(11205..12116)
                     /gene="trxB"
                     /locus_tag="VVR63_000952"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HEU6128981.1"
                     /translation="MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLPGGQMNNTSD
                     IENYPGYANISGPELAEKMFEPLENLGVEHIYGYVKNVEDHGDFKKVMTDDQTYETRT
                     VIVATGSKHRPLGVPGEEELNSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEALFLT
                     RFAKTVTIVHRRDQLRAQKVLQDRAFANEKISFIWDSVVREIKGENRVESVVFENVKT
                     GQVTEQAFGGVFIYVGLDPLSDFVKELNIQDQAGWIVTDNHMKTAVDGIFAVGDVRLK
                     DLRQVTTAVGDGAIAGQEAYKFITEHS"
     gene            complement(12182..12406)
                     /locus_tag="VVR63_000953"
     CDS             complement(12182..12406)
                     /locus_tag="VVR63_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HEU6128982.1"
                     /translation="MLLQLFSLYFESLILTTILVLIFLGIWIGLRAMSGVDKTARARQ
                     AHLYDMIMIGVLVVPVLSFAVMSLILVFKA"
     gene            complement(12484..13227)
                     /locus_tag="VVR63_000954"
     CDS             complement(12484..13227)
                     /locus_tag="VVR63_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU6128983.1"
                     /translation="MIKISNLSKSFSGQTVLDHLNLDIQKGEVVALIGSSGAGKSTFL
                     RSLNYLETPDSGSIQIDGFSVDFSKITQEEILALRRKLSMVFQQFNLFERRTALDNVK
                     EGLVVVKKLSDQEATKIAKEELAKVGLSDRENHYPRHLSGGQKQRVALARALAMKPDV
                     LLLDEPTSALDPELVGEVEKSIADAAKSGQTMILVSHDMSFVAQVADKILFLDKGKII
                     ESGTPDEIIHTPKEERTKEFFASYKRTYI"
     gene            complement(13227..14027)
                     /locus_tag="VVR63_000955"
     CDS             complement(13227..14027)
                     /locus_tag="VVR63_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001103446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU6128984.1"
                     /translation="MNVTTILASDWYQNLMQLIPDGKLFSLRSVFDGIPRIVQQLPTT
                     IMLTIGGALFGLVLALLFAIVKINRVKILYPLQAFFVSFLKGTPILVQLMLTYYGIPL
                     ALKALNQQWGTGLNINAIPAAAFAIVAFAFNEAAYASETIRAAILSVNPGEIEAARSL
                     GMTRAQVYRRVIIPNAAVVATPTLINSLIGLTKGTSLAFSAGVVEVFAQAQILGGADY
                     RYFERFISVALVYWVVNIGIESLGRFIERKMAISAPDTVQTDVKGDLR"
     gene            complement(14185..14541)
                     /locus_tag="VVR63_000956"
     CDS             complement(14185..14541)
                     /locus_tag="VVR63_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEU6128985.1"
                     /translation="MLEFIEYPKCSTCKKAKQELNQLGVDYKAVHIVEETPSQEVILN
                     WLETSGFELKQFFNTSGIKYRELGLKDKVGSLSNQEAAELLASDGMLLKRPILVENGT
                     VKQIGYRKSYEELGLK"
     gene            complement(14554..15066)
                     /locus_tag="VVR63_000957"
     CDS             complement(14554..15066)
                     /locus_tag="VVR63_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001170346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HEU6128986.1"
                     /translation="MQKKYVKILYSSPIGILSLVADDHYLYGIWVQEQKHFERGLGDE
                     TIEEVVSHPILDPVIACLDDYFKGKPQDLSNLLLAPIGTNFEKRVWDYLQGIPYGQTV
                     TYGQIAQDLQVASAQAIGGAVGRNPWSILVPCHRVLGAGKRLTGYAAGVEKKAWLLEH
                     EGVDFKDINK"
     gene            complement(15066..15560)
                     /locus_tag="VVR63_000958"
     CDS             complement(15066..15560)
                     /locus_tag="VVR63_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6128987.1"
                     /translation="MEIRLAFPNEVDAIMQVMEDAKKCLADAGSDQWQNGYPNADVII
                     DDIISGQAYVALEEGELLAYAAVTKSPEEAYEAIYEGNWQAGESEYLVFHRIAVAADV
                     QGKGVAQTFLEGLIEGFDYLDFRSDTHAENKVMQHIFEKLDFKQVGKVPVDGERLAYQ
                     KLKK"
     gene            15695..16141
                     /locus_tag="VVR63_000959"
     CDS             15695..16141
                     /locus_tag="VVR63_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HEU6128988.1"
                     /translation="MKTTFSYPKWAEIPNIDLYLDQVLLYVNQVCAPISPNKDKGLTA
                     SMVNNYVKNGYLTKPDKKKYQRQQIARLIAITTLKSVFSIQEIAQTLNTLQTQASSDQ
                     LYDAFVDYMNQGIDPANPIIQTSCQTIKLYHQTLDLIDHTQEEVIQ"
     gene            16138..16785
                     /locus_tag="VVR63_000960"
     CDS             16138..16785
                     /locus_tag="VVR63_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HEU6128989.1"
                     /translation="MNTSLKLSKQLSFGEEIANSVTHAVGAVIMLILLPISSIYSYEA
                     HGFLSSIGVSIFVISLFLMFLSSTIYHSMAYGSTHKYVLRIIDHSMIYVAIAGSYTPV
                     VLTLMNNWFGYLIIVIQWGTTIFGILYKIFAKKVNEKFSLALYLIMGWLVLAIIPAII
                     SQTTPVFWSLMVTGGLCYTVGAGFYAKKKPYFHMIWHLFILAASVLQYIAIVYYM"
     gene            complement(16806..17387)
                     /gene="pdxT"
                     /locus_tag="VVR63_000961"
     CDS             complement(16806..17387)
                     /gene="pdxT"
                     /locus_tag="VVR63_000961"
                     /EC_number="3.5.1.2"
                     /EC_number="4.3.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase glutaminase
                     subunit PdxT"
                     /protein_id="HEU6128990.1"
                     /translation="MKIGILALQGAFAEHAKVLDQLGVESVELRNLDDFQQDQSDLSG
                     LILPGGESTTMGKLLRDQNMLLPIREAILSGLPVFGTCAGLILLAKEITSQKESHLGT
                     MDMVVERNAYGRQLGSFYTEAECKGVGKIPMTFIRGPIISSVGEGVEILATVNNQIVA
                     AQEKNMLVSSFHPELTDDVRLHQYFINMCKEKS"
     gene            complement(17388..18263)
                     /gene="pdxS"
                     /locus_tag="VVR63_000962"
     CDS             complement(17388..18263)
                     /gene="pdxS"
                     /locus_tag="VVR63_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012054698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase lyase subunit
                     PdxS"
                     /protein_id="HEU6128991.1"
                     /translation="MTENRYELNKNLAQMLKGGVIMDVQNPEQARIAEAAGAAAVMAL
                     ERIPADIRAAGGVSRMSDPKMIKEIQEAVSIPVMAKVRIGHFVEAQILEAIEIDYIDE
                     SEVLSPADDRFHVDKKEFQVPFVCGAKDLGEALRRIAEGASMIRTKGEPGTGDIVQAV
                     RHMRMMNQEIRRIQNLREDELYVAAKDLQVPVELVQYVHEHGKLPVVNFAAGGVATPA
                     DAALMMQLGAEGVFVGSGIFKSGDPVKRASAIVKAVTNFRNPQILAQISEDLGEAMVG
                     INENEIQILMAERGK"
     gene            complement(18415..19794)
                     /locus_tag="VVR63_000963"
     CDS             complement(18415..19794)
                     /locus_tag="VVR63_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEU6128992.1"
                     /translation="MSKIVVVGANHAGTACINTMLDNFGNENEIVVFDQNSNISFLGC
                     GMALWIGEQIDGAEGLFYSDKEKLEAKGAKVYMNSPVLSIDYDNKVVTAEVEGKEHKE
                     SYEKLIFATGSTPILPPIEGVEIVKGNREFKATLENVQFVKLYQNAEEVINKLSDKSQ
                     HLDRIAVVGGGYIGVELAEAFERLGKEVVLVDIVDIVLNGYYDKDFTQMMAKNLEDHN
                     IRLALGQTVKAIEGDGKVERLITDKESFDVDMVILAVGFRPNTALADGKIELFRNGAF
                     LVDKKQETSIPGVYAVGDCATVYDNARKDTSYIALASNAVRTGIVGAYNACGHELEGI
                     GVQGSNGISIYGLHMVSTGLTLEKAKAAGYNATETGFNDLQKPEFMKHDNHEVAIKIV
                     FDKDSREILGAQMVSHDIAISMGIHMFSLAIQEHVTIDKLALTDLFFLPHFNKPYNYI
                     TMAALTAEK"
     gene            20089..21012
                     /locus_tag="VVR63_000964"
     CDS             20089..21012
                     /locus_tag="VVR63_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HEU6128993.1"
                     /translation="MTLRSHSERLMGTTITISLVDEQADIFLQKSFDLLKELEYRFNA
                     NSQESELMEINYQAGIAPVTVHPDLFELISLGLEHSLALSSHLNISIGPLIQTWRIGF
                     SDAKVAQPQEIESVLPLINPHGIKLDSSTSTVFLKQKGMKIDLGCLAKGYSADKVAQF
                     LRKEGVTSALINLGGNILTIGKNQARGDNPWQIGIQDPANPRGNHLMTIPVVNKSVVT
                     SGIYERHLTVDGQDYHHIFDSQTGYPVETELASLTIISDKSVDGEIWTTRLFGERPAS
                     ILWQVESLEGIEVILIDKEGHLSCSSGIPTL"
     gene            21072..21677
                     /locus_tag="VVR63_000965"
     CDS             21072..21677
                     /locus_tag="VVR63_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEU6128994.1"
                     /translation="MLKLIAIVGTNSKCSTNRQLLQYMQKHFTDKAEIELVEIKAIPV
                     FNKPADKQVPAEILEIAAKIEEADGVIIGTPEYDHSIPAVLMSALAWLSYGIYPLLNK
                     PIMITGASYGTLGSSRAQLQLRQILNAPEIKANVLPDEFLLSHSLQAFNPSGDLVDLD
                     VIKKLDAIFDDFRIFVKITEKLRNAQELLRKDAEDFDWENL"
     gene            21696..22940
                     /locus_tag="VVR63_000966"
     CDS             21696..22940
                     /locus_tag="VVR63_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEU6128995.1"
                     /translation="MKFVGLVGSNYDQSYNRKLLEFIRRYFKLKFELEVLEIDEVPMF
                     NQDEKWDESFQLRFLYNKITRADGVIIATPEHNHTISASLKSVLEWLSYEVHPFENKP
                     VMIVGASYYDQGTSRAQVHLRKILDAPGVNAYTLPGNEFLLGKAKEAFDNNGNITNEG
                     TVKFLETCLDNFVKYVGVVSKLKKPKPIESEDLDCGKPIATTITEVDPDDPEWVEKVA
                     AITGAVSGDTYVKLDHGILTVNQIDMFLKAMPFELTYADDNNQFLYYNNAHQDPDTMF
                     AKRVPPQSGSRMSTVHGSLPPARMKNVEWVIGTLRNGNQEYVRTIVPGSPAGVINTHN
                     YQAMYYPDGSYAGINEIVFNFQPWLDWYLKETGQRLVGGSGPFAPAAGDHGDADATSG
                     ASDSGDAGGHGGDADATAGASY"
     gene            complement(23163..23420)
                     /locus_tag="VVR63_000967"
     CDS             complement(23163..23420)
                     /locus_tag="VVR63_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002901318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HEU6128996.1"
                     /translation="MDPKKIARINELAKKKKTEGLTPEEKVEQAKLREEYIEGYRRAV
                     RHHIEGIKIVDEEGNDVTPEKLRQVQREKGLHGRSLDDPNS"
     gene            complement(23462..25498)
                     /locus_tag="VVR63_000968"
     CDS             complement(23462..25498)
                     /locus_tag="VVR63_000968"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HEU6128997.1"
                     /translation="MTKNLLVELGLEELPAYVVTPSEKQLGEKMAAFLKGKRLSFEAI
                     QTFSTPRRLAVRVTGLADKQSDLTEDFKGPAKKIALDSDGNFTKAAQGFVRGKGLTVE
                     DIEFREIKGEEYVYVTKEEIGQAVEAIVPGIVDVLKSLTFPVSMHWAGNSFEYIRPVH
                     TLTVLLDEQEFDLDFLDIKGSRVSRGHRFLGKETKIQSALSYEEDLRKQFVIADPCER
                     EQMIVDQIKEIEAKHGVRIEIDADLLNEVLNLVEYPTAFMGSFDAKYLEVPEEVLVTS
                     MKEHQRYFVVRDQDGKLLPNFISVRNGNAERLKNVIKGNEKVLVARLEDGEFFWREDQ
                     KLVISDLVEKLNNVTFHEKIGSLREHMIRTGQITVLLAEKAGLSVDETVDLARAAAIY
                     KFDLLTGMVGEFDELQGIMGEKYTLLAGETPAVAAAIREHYMPTSAEGELPESKVGAV
                     LAIADKLDTILSFFSVGLIPSGSNDPYALRRATQGVVRILDAFGWHIAMDELIDSLYA
                     LKFDSLTYENKAEVMDFIKARVDKMMGSTPKDIKEAVLAGSNFVVADMLEAASALVEV
                     SKEEDFKPSVESLSRAFNLAEKAEGVATVDSALFENDQEKALAEEVETLVLSGPASQQ
                     LKQLFALSPVIDAFFENTMVMAEDQAVRQNRLAILSQLTKKAAKFACFNQINTK"
     gene            complement(25758..26675)
                     /gene="glyQ"
                     /locus_tag="VVR63_000969"
     CDS             complement(25758..26675)
                     /gene="glyQ"
                     /locus_tag="VVR63_000969"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HEU6128998.1"
                     /translation="MSKKLTFQEIILTLQQFWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLESLEK
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATSPVTAE
                     VTYGLERLASYIQEVDSVYDIEWADGVKYGEIFIQPEYEHSKYSFEISDQEMLLENFD
                     KFEKEAGRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKRLGYPLLDEETRVKLLAEDSE"
     gene            complement(26694..27455)
                     /locus_tag="VVR63_000970"
     CDS             complement(26694..27455)
                     /locus_tag="VVR63_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEU6128999.1"
                     /translation="MDNLYLVKDDSQLATFRDFVVRNTEKLKDYQSFLKNELAVCDLP
                     QAVIWSDFNAATQIIRESAVPAYTNNRRMVMAPDLAVWKELYLYQLMDYECSEQTQAI
                     ESHYHSLSENFLLQIVGHELAHWSEHFLDDFDGYDSYIWFEEGMVEYISRKYFLTEEE
                     FQAEKICNQSLVELFQKKYGWHSLNDFGSSTYDKNYASIFYEYWRSFLTVDKLVENLG
                     SVQAVLDSYHLWANTEKTFPLLDWFVQQKLIEKEI"
     gene            complement(27728..28570)
                     /locus_tag="VVR63_000971"
     CDS             complement(27728..28570)
                     /locus_tag="VVR63_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HEU6129000.1"
                     /translation="MNTYQLNNGVKIPVLGFGTFKAKDGEEAYRAVLEALKAGYRHID
                     TAAIYQNEESVGQAIKDSGVPREDLFVTTKLWNSQQTYEQARQAFAESLEKLGLDYLD
                     LYLIHWPNPKPLRENDQWKIRNAEVWRAMEDLYQEGKIRAIGVSNFLPHHLDALLATA
                     TIVPAVNQVRLAPGVYQEEVVAYCREKGILLEAWGPFGQGELFDSKEVQEIAANHGKS
                     VAQIALAWSLAEGFLPLPKSVTASRIQANLDCFGIELSHEEHETLKTIAVHSGAPRAD
                     DMDF"
     gene            complement(28684..30075)
                     /locus_tag="VVR63_000972"
     CDS             complement(28684..30075)
                     /locus_tag="VVR63_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEU6129001.1"
                     /translation="MNKSRLGRGRHGKTRHVLLALIGILAISICLLGGFIAFKIYQQK
                     SFEQKIESLKKEKDDQLSEGNQKEHFRQGQAEVIAYYPLQGEKVISSVRELINQDVKD
                     KLESKDNLVFYYTEQEESGLKGVVNRNVTKQIYDLVAFKVEETEKTSLGKVHLTEDGQ
                     PFTLDQLFSDASKAKEQLIKELTSFIEDKKIEQDQSEQIVKNFSDQDLSAWNFDYKDS
                     QIILYPSPVVENLEEIALPVSAFFDVIQSSYLLEKDAALYQSYFDKKYQKVVALTFDD
                     GPNPATTPQVLETLAKYDIKATFFVLGKNVSGNEDLVKRIKSEGHVVGNHSWSHPILS
                     QLSLDEAKKQITDTEDVLTKVLGSSSKLMRPPYGAITDDIRNSLDLSFIMWDVDSLDW
                     KSKNEASILTEIQHQVANGSIVLMHDIHSPTVNALPRVIEYLKNQGYTFVTIPEMLNT
                     RLKPHELYYSRDE"
     gene            complement(30310..30687)
                     /locus_tag="VVR63_000973"
     CDS             complement(30310..30687)
                     /locus_tag="VVR63_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HEU6129002.1"
                     /translation="MICQFIRDMLDLPAKNVTILEGSNIHVLPSMPYSAQDFYTSIDV
                     LAELDNGIQVIIEIQVHHQNFFINRLWAYLCSQVNQNLEKIRQREGDTHQSYKQIAPV
                     YAIAIVDSNYFSDDLAFHSFIVK"
     gene            30902..31879
                     /locus_tag="VVR63_000974"
     CDS             30902..31879
                     /locus_tag="VVR63_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEU6129003.1"
                     /translation="MLKLGVIGTGAISHHFIEAAHTSGEYQLVAIYSRKLETAATFAS
                     RYQNIQLFDQLEVFFKSSFDLVYIASPNSLHFAQAKAALSAGKHVILEKPAVTQPQEW
                     FDLIQTAEKNNCFIFEAARNYHEKAFTTIKNFLADKQVLGADFNYAKYSSKMPDLLTG
                     QTPNVFSNRFAGGALMDLGIYPLYAAVRLFGKANDATYHAQQLDNSIDLNGDGILFYP
                     DYQVHIKAGKNITSNLPCEIYTTDGTLTLNTIEHIRSAIFTDHQGNQVQLPIQQTPHT
                     MTEEVAAFAHMIQQPDLNLYQTWLYDAGSVHELLYTMRQTAGIRFEAEK"
     gene            31876..32958
                     /locus_tag="VVR63_000975"
     CDS             31876..32958
                     /locus_tag="VVR63_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU6129004.1"
                     /translation="MKTKLPTEWQELSDQLGFQEFTPIQTQLFEPLLAGENLLGVSQT
                     GTGKTLAYLLPSLLRLQKKKAQQLLILAPNTELAGQIFDVCKTWAEAIGLTAQLFLSG
                     SSQKRQIERLKKGPEILIGTPGRIFELIKLKKIKMMNVETIILDEFDQLLDDSQIHFV
                     EKITHYAPRDHQLVYMSATTKFDQEKIVPNTRTIDLSDQKLDNIQHFYMQVDQRHRVD
                     ILRKLAHVEDFRGLVFFNSLSDLGNAEEKLQYRDILAVSLASDVNVKFRKVILEKFKD
                     NQLTLLLATDLLARGIDIDSLECVVNFDIPRDSETYTHRAGRTGRMGKEGYVITLVTH
                     PEEIKKLKKFASIREIVLKNQELYIK"
     gene            complement(33022..>33168)
                     /locus_tag="VVR63_000976"
     CDS             complement(33022..>33168)
                     /locus_tag="VVR63_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HEU6129005.1"
                     /translation="RKRGFKNKAFRTLEDVMNQLQDVIQGLEKEVIKSIVNRRWNRML
                     FESR"
BASE COUNT         9847 a         7419 c         5938 g         9964 t
ORIGIN      
        1 actaccgaac cactccgacg ctgatcatgg tggtacagcg tgattgcttg attctcagct
       61 ttcccagaca aaaaggtcca atagtaggtc agatggctat cattctctag aacccgatag
      121 gaggtttcat ctgcatgaag taagggctga atcaatagtc tcgttataaa ggggctttag
      181 gaataggagc ttttacaatt ttatcacttg gattattctt actgcatgtt tggcatttgt
      241 aagcgtgttg gatatgatcc actcttttta attgcgcagg aataaagacc aattcttgtc
      301 gttgaaggct cgctccaatc tcttttaaat cgtcctgaca atcagggcaa atgctctctt
      361 ctacttgatg atgaacttct tctgaatcaa attgggcaag aatagcttga cgtttccctt
      421 tagatttctt acgtttgtag gtaatttcct ctgtttcaac tgggaacatc tccatctttc
      481 tcagatggag actcttcctc aaaaaggttg agttgtccaa aagggcaaac acttttctca
      541 gaggattttc cagagagctt ttgcgttaga taagccactt gttcacacag aagggaaagt
      601 tcattagtga gactatcaat tatagcactc tgttgttgaa tgattttcaa tcttctccca
      661 tagactttcc tccttatttc ctaactttat tatatagtgt attgaatcta taacagtaca
      721 ccttgactgc taaaatattt ctataaatta atttgacttt cctgatagag atgttcatat
      781 cttatttcaa ttcactatac taaaaagaaa gtcctcattt caatagaaat cacgactttc
      841 tgataaattt attttgggag tgatagaaaa gcccttcata agccaatcta cttgttcagg
      901 tgtgagagct ttgacatcct tttctgtact gggccaagtc agtctgccgt tctcaaagcg
      961 tttatatagt agccaaaatc cttgaccatc ccagtaaagg gctttaaagc ggtctttacg
     1021 tccaccacaa aagagaaaaa cttgaccgga gaaaggatcc aattcaaagt gggttttaac
     1081 cagataagcc agtgaatcga ttccttgtct catatcagtc ttcccacaca cgagatagac
     1141 ctgccctagg ctagatagat gaattgtcat agagcaacac cttatccaaa agctgttcta
     1201 ccatttcgag attgagagat tgaaaaaaac ttacttcaag cttgccaata cgaattttaa
     1261 gcagaatatc atttctcttt ttagaatcaa aaggacgaga ttgtggaatc tctacaggaa
     1321 caataggttg tggcattaaa atatcctcca atagttttac tttactaata gtatacagga
     1381 ggaactccat gaatgataga taccttgtta tgacgcgctt actatattag aaagttggct
     1441 ctctaattaa attaattctc attatatata tcaaaagacc gcagtttgaa aactacggtc
     1501 taattttttg tccaaatgta aatcacttgg aactattatt caatttattc tttttagtaa
     1561 atgttcccgt tttaatccca gttacagttt ttaatcctct gtaaccgttg attttacaaa
     1621 gcttttaatt tttttgcgat tactcccact caactgttgc aggtggttta cttgtaatat
     1681 cgtagacgat acggttaaca tgatccactt catttacgat acgtactgag attttttgaa
     1741 gtacttccca tggaattttg gcaaaatcag cagtcatacc atcgatagaa gtgatagcac
     1801 ggattgcaat cgtgtagtca tacgtacgac cgtcacccat aacaccgact gaacgaacgc
     1861 ctgtgttaac agtgaagtat tgccaaatat cgcggtcaag tccagcttta gcgatttctt
     1921 cacgaagaat agcgtctgat tcacgaacgg tttcaagttt ctcttcagtg atttcaccca
     1981 tgacacggat agcaagtcct ggtcctggga atggttggcg ccatacgata tggtctggca
     2041 taccaagctc tgtaccaaga gcacgaactt catccttgta aagagtattg agtggttcaa
     2101 tcaattcaaa ctgcatatct tctggaagac cacctacgtt gtggtgtgac ttgatagttt
     2161 gagctgtatc cgtaccagac tcgataacat ctgtatataa agtaccttga gcaaggaatt
     2221 tcacatcttt gagcttgctt gcttcgtcat cgaatacata gacaaactcg ttaccgatga
     2281 ttttacgttt ttgttcagga tcagaaacgc cagcaagttt gtcaaggaaa cgtttagcag
     2341 cgtctgcttt gacgatattc aaaccaaact taccaccgag catgtccata acttgatcag
     2401 cttcgccttt acgaagaaga ccgtggtcta cgaagataca gatcaattga tcgccaatcg
     2461 ctttttggag aagaacccca acgacagatg agtcaacacc acctgataga ccaagaagga
     2521 cacgtttatc accgacggtt tcacgaattt ttttgatctg catgtcaatg aaattatcca
     2581 ttgaccagtc acctttagcc ttacaaatgt taagggcaaa gttacgaagg atatcatttc
     2641 cgtatacaga atgacgaact tctgggtgga attggatacc gtaaatgtgt ttatctgggt
     2701 tttcgatggc tgcgtatagg cagtcagctg atgtacctgt acgaacaaag tcagcaggaa
     2761 tctcagtaac cgcatcacca tggctcatca aaacagtctg ttcatcaggt gttgattcaa
     2821 aaagcgctga tggtgtgtga gttagggttg attgaccgta ttcacgattt ccagcatcac
     2881 ctgcaggaac aacttttcct ccaagtttat gggtcaataa ctgcatacca taacagattc
     2941 ccaaaattgg aattccgagt tcgaagattt ctgggtcaat atcaaatgaa ccatcttcat
     3001 atacagaatt tggaccacct gatagaataa ttcctacagg attgacttca cgaacttcag
     3061 cagctgaaat tttatggctt tttagttctg aaaaaacacc aatctcacgg atacggcgtg
     3121 aaatcagctg gttgtactgg ctaccatagt ccaatacgat gattttttct acatcttgca
     3181 aatcagttga aatgttgctc atctttttcc tttctcaaaa gaaatatctt ttctcaatat
     3241 tctatcacaa ataagggcga attaccaact aaacaaggcg aagtttgact ttttctagtt
     3301 tattggggta caatagagaa aagatagaaa tgaagtgaaa aatatgctac ctgcttatat
     3361 gaaaatccat gatcagataa aaaaggatat tgacgagcac cgttgggcta ttggtgagag
     3421 gcttcccagt gaaagagatt tagctgagca gtttgcggtc agtcgcatga ccctccgcca
     3481 agccgtatct ctattagtcg aagaaggcgt cttagagcgc cgtgtaggaa gcggcacctt
     3541 tgtttccagt actcgagtac aagaaaagat gcgagggaca accagtttta ctgaaattgt
     3601 caaatcccaa ggtaaagttc cctctagcca gctcatttcc tacaaaaaaa ccattcccaa
     3661 tgagcaagaa gttgccaagc taggaatttt tccaacggac aatattatcc gaatggagcg
     3721 ggtccgctat gccgaccaag ttcccctagt ttatgaagtt gcttctattc ctgaaaaatt
     3781 cattaaggac tttaaaaaag aagaaatcac cagtcatttc ttccaaacct tgcaaaaaca
     3841 tggctatcgt atcggcaaat ctcaacagac catctatgct cgccttgcta aagaaaagat
     3901 tgcccactat ttggaagttg aaaaaggaca tgctattctt ggattgaccc aggtttccta
     3961 cctagaagat ggtactgctt ttgaatacgt aaaaagtcaa tatgtaggcg aacgctttga
     4021 attttatctt gaaaataatt agattaccac gcaaaaactc tctgtcacgg acaaagagtc
     4081 ttttttattt ttctaagaat aaatctttca aagaaatcaa agttacagca aacaatatca
     4141 ttgccatacc aataaaatca atgggataaa attgttcatt cattattaag aaggcaaaga
     4201 aaaccgccga tattggctca attgaagcca acaagcttga cttgaccggt cctatcagac
     4261 tggctccttt aaggaaagct gtataggcaa agacagtccc gataaggata atgcctgcaa
     4321 acgcaaggag aaaatcaaga ctagtcggga tatcggcctg tagaacccct gtaaaaggaa
     4381 gggcgaccaa acctgctatg accatcccca caccaatgac caagctgctc ccccactttt
     4441 taatcaaggc tatgggtaaa atgatataca aagcataagt caaggcagaa aagagacccc
     4501 agaacaggcc agcaggtgtc atggataact ggtccaactg cccatgtgtt gcgatcagga
     4561 aggttcctcc gatggcgaat atgatggaaa ctatctctcc cagtgtcggt gccaccctat
     4621 ccttgataca gctataaatt aaaattccga caggacaaac atactgaagc accgtcgctg
     4681 ttcccgcatt ggtctcctga atagcagaca gataggcgaa ttggttgaga aaaagaccaa
     4741 tcagagcaaa aataagaaga gacagcaaac tctttctatc ctttaaaaag accagtattt
     4801 tatcctttgc agtagcataa gccaagagca tgagaattcc accagcgatt aaaagacgca
     4861 agttggtcaa gaccagagcc gaaattccgt gtgccattag gtattggcca ctcgttcctg
     4921 acaaccccca agcaatacca gccacaactg ttagtaaagt cccttttaaa ctatttgaca
     4981 tgtctctcct tactcttctt tgcgaatcaa gttcatcact tgattgcggt ctaatatcca
     5041 ttgagctctc tcgtcctttt cataggtacg attcgatagg aaaatagtgg cttcttgctt
     5101 ctgacgattc cacatgataa aggtacctgt atagcccgta tggtctagcc aatctccttc
     5161 caaattccat gctaaagaac gttccttgtc atccaaagga gaaaaatttt gatttaagtc
     5221 tcttgcaaaa tcatctgcta aatagtgttc taaaaagatt tgtaaatcct ttatagtcga
     5281 aaataaacca gcactcccag catgtctacc caggagacga gccttgggat catgcactat
     5341 gcctgcctct acacctctaa ctgttggaac agcaagctca actggcccaa acttggtttc
     5401 cgtcattccc caaggtttcc agacttgatc ctttaaaatc acatccaaat cttgattaaa
     5461 aattctttcc aaaataaagc ccaacagcaa aaaatggaca tccgaataaa gaaaggctgg
     5521 ctgacttcgt ctgttgagat gaaacatcgc ttcctttaat tcaggggctg ttaaaagatc
     5581 acgattagga ataaaaggat caaggtctgt tgcatgagtc aagagctggc gaatagtgat
     5641 gtctggataa tcactctcag gtaaaaaatc tattaccagt ctatcaatat ctaattgacc
     5701 tatttcccac aagaaggtac aaactgtgcc aaccccaaca accttgctga cactagctag
     5761 gtcataaact agtcctgcct cagtctgcaa gccatgctct gggtcactct ggcctaaata
     5821 gaactctgtc cattgattgt ccttaaaata cgcaaaagag gctccgggat aaattcctgc
     5881 ctcgatttgt tcttctattt ttttaataat cttggtccac ttcatacttc ttcaaaccac
     5941 aattcaacat tatttctatc tttacaaagg aagaattttt cagacttagg aataaaatat
     6001 tcagtagact caaacttctg gcgaagactt gctatgtcta attcattgac caagaacttg
     6061 agcatagata agtcccaggt aaccgtattg tccacagtca aatcctgccc ctgagctgga
     6121 ataaaatcaa gggatgcccc aatttcagat gattccaaga aactttcgat atcagttggg
     6181 agatgtaatt ccatagaaat ctcaaattta cttaaagaaa ttgatgccaa atctgtttga
     6241 aattcaggct tttctcctac ttctactaga cttgctatgt catcttccgc atgaatcaaa
     6301 atcaaatcat cttctggtga gaaaatttca aaagcgtagc cattttgacc tttatataat
     6361 cgatgaatcg aatctgtttt agataagatt ccttcaattt ctaagggatt ttccaccttg
     6421 acaatcaatc tagctagttt ttttcttccc tctaccttac gagtacgcat actgggagct
     6481 tcttctaaaa ccagcttttc aagacccgtt tggtcaccta gtgacagaaa ggccgattct
     6541 tctaacaagg ccttcattcc aagggtttca atataaaatg tttcatttaa ttttctatta
     6601 ttagctttta aagtaggaat aatccgtaca atctgattta cattcataaa ttcctccgtc
     6661 actttttatt ttaaaggatt ttagaatttt ttacaagata ttatgctcaa atttaacatt
     6721 atttagctat ttagtaaaga tagtctttca aggattttga caaagcctga taaccagcaa
     6781 tactgaggtg cagtccatca gttgtatatt cttttttgag ttggcctgct tggtctgtca
     6841 aacaatcaaa tactggcaca aattccacct gcatataggc agatgcaagc tcttgatagg
     6901 cttgattcca gttctgaatt ttttcattcg agcggatata gactgcctgc tggtactcct
     6961 ctctctcatt gacaggcaaa atggaaagca atttaatctc tgtcaatgga taatcgcgag
     7021 caacggattg aatgatagct tcgagattat tgagagcctc attcacagga acatcctttc
     7081 cgatatcatt tgtcccaatc agaagaaaaa ttttatctac tgctccacca tatagatgag
     7141 catcaaggtt ctctagtaac agtcctgtct gatagccacg aattcctcga ttgacaatcg
     7201 tctttgaagt cccaaatagc tcctgtagag gataatactc gacaatggaa tccccaataa
     7261 aaagaatgtt tggttctaca acagaaatgt gatttaggtg acgatactta gtttgaattt
     7321 tttcttgttc ctttaggagc caattttcta ataactgtac tgccacttca ttctcctttt
     7381 tctaaccagt tttccaagac ttgataaact cctccttggc tgttggctgg tgctagagca
     7441 gtcgccacag ctttggcttt ctcatcagca ttttccatcg cataggcaat tccagccatt
     7501 tcaagcattt caacatcatt ttcactatca ccaaaagcca tgatttcttg ggatttcaag
     7561 tcccagcgct tgagtaattc ctccaagccc catgctttat gaatcccagc ttggaggata
     7621 tcaatgcaac catagccact ggatacagct cggacacggc catcaaagag agcattgatt
     7681 tcttccaaaa ccgaactcaa acgttcctca ccaacaacca tgctcatctt gagcacacca
     7741 ccaaagaggt cagatgttaa ttcatccaca aattgcatcc gttggtagaa tttttcaatc
     7801 atttctggag tcataaaact ttcaagatct gtaaaaatcg taccttcctt gacaaaatca
     7861 cccttcatcc ccgttacaac aaactggtcc tgacacgctc gacccttgaa atgagtcaaa
     7921 gccttgttga caatggcgtc atcccatgtc tgagcctgaa tcaattcatt gttttcaaaa
     7981 atacgagcgc cattagcaac aaccagaacc acccgatcca ccaagggact cagtagttgt
     8041 ctcatgcggt gaatttcatt gcccgtcgca atgacaaaac gaatgcccct ttgatccaac
     8101 tgatctaaaa tcttttccaa tcgtgggaga tcaagctgac ctctagcatc cagcaaggtc
     8161 ccatccatat ctgtcgcaat taccttaatc atcatttact ttcctctgga ttcaagctaa
     8221 taccacttca atcccacatg ttcattcatt tctttatagg ctgtatcaat tcgttcctta
     8281 gtcgcttcat ctaactggtc acgatgactg ccatcctcta taaaatcttc caaaatataa
     8341 gtttggtaat gatacaaggg atatccttct ggtgaaaagg ttccctttgg tgttcgattg
     8401 acccaagtag gatgagcttt agctgttccg atagttgttt ttccatcctt cttcttgatg
     8461 gtgacatcca tgagaacacc acgttcagtc cacttagcat tctcttcatc tcccatagat
     8521 tcaattcgtt gattggaaat gaagttcccc atttaataga caatgagctt cttatctcca
     8581 tctttttcca ccgtttcaga tggttcaaca acgtgaggat gccctccaaa gataatatcc
     8641 gctccccaat caatcatctt gtgataaaga gctttttgtt cttcagttgg ttccaatcga
     8701 tactcaacac ccatctgagg catgataatg gtgatatctg cttccttctc tgcccgttca
     8761 acttcagcct ttatcttatc ttcgtttaaa tctgaaagat aacgattata gtcttcctga
     8821 gaaatatact gctcaattcc attgaaacca taggaatagg ctaacaatgc aaccttgata
     8881 gcattcactt ccttaatgac cagcggagcc tgagcacgtg gttcgtgcgt ataaactccg
     8941 attggagtga ttccagcttt ctcaataata tcggccattg aaataactcc ctcaatttgc
     9001 gaatccaaaa tatgattatg agctaaatcc agcacatgat aacctgcctc cttaatagca
     9061 tccataactt caacaggagc attaaagaga agataacccg ctaaataatg atccttatta
     9121 atggttcctt caaaatcacc aatagctaaa tctgcttgct tgagccaagg agtcacatac
     9181 tcaaaatttt catgaaagtc ataggtaccg tcttcttttt tagctgaaaa gaaaagtcca
     9241 tcgtggtaga gcaaatcccc gtgggccata attctggcag ttttttcctc ttcctactcc
     9301 tgagactttt gcttagtccc ctcttgagaa atagtatctc gtttttgact agtcaaggga
     9361 ttccttggaa gctttcaaac aacaagacca agcccattga taaaccaact gctagcaaga
     9421 gtatcgccac aaatccctta ttgctccact tgcgataact cctaaaaagt ttaccaagcc
     9481 cttcataaaa cgaaaagcta aaccaccctg atttcgattt tgtcttcttt gtatcttcgt
     9541 tctccctact ttcttatgca agccttttct ttttattata tcacagataa gtatttcttt
     9601 cacaattgaa ttgaacttcc tatctatttt ctataaatcc taaatgccat aatgctttca
     9661 attcttgtca ttttgtgata tcatgtagag gaaatgaact aatccacagt ggcttattcc
     9721 aagtatacca cttgggcttt ggcagtagct aactgcacta aacataatat aaggagagaa
     9781 aatgtctgca atagaacgta ttacaaaagc tgctcactta attgatatga acgatattat
     9841 ccgtgaaggg aatcctactc tacgcacggt tgctgaggaa gtcactttcc ccctatctga
     9901 ccaggaaatc atcctaggcg aaaagatgat gcaattcctt aaacattccc aagatcctgt
     9961 catggctgaa aaaatgggac tccgcggtgg tgttggactg gctgctcccc agttagatat
    10021 ctcaaaacgc attatcgctg ttttggtacc taatattgtt gaagaaggcg aaactccaca
    10081 ggaagcctac gatttggaag ccattatgta caatccaaaa atcgtctctc actctgttca
    10141 agatgctgct cttggcgaag gagaaggttg cctgtctgtt gaccgtaacg tgcctggcta
    10201 tgttgttcgc catgcccgcg ttactgttga ctactttgac aaagatggag aaaaacaccg
    10261 tatcaaactc aaaggctaca actccattgt tgttcagcat gaaattgacc acattaacgg
    10321 tatcatgttt tacgatcgca tcaatgaaaa agacccattt gcagttaaag atggtttact
    10381 gattcttgaa taaagaaaat cccgttgcaa gacggggttt tgtgttataa tagaggcatg
    10441 aaaacaaatg atattgtcta tggtgtccac gctgttaccg aagccctcct tgcaaataca
    10501 ggaaacaaac tctacctcca agaagatctc cgaggtaaga atgttgagaa agtcaaggaa
    10561 ctagctacag aaaagaaggt gtccatttct tggacatcaa aaaaatctct ctctgagatt
    10621 actgaaggtg ctgttcatca aggttttgtt ctacgagtgt ctgaatttgc ctatagcgag
    10681 ctagattaca tccttgcaaa aacacgccaa gaagaaaatc cacttctatt gattctagat
    10741 ggtctaaccg atccccataa tctgggttct atcttgcgaa cagccgatgc gaccaatgtt
    10801 tcaggtgtca tcattcccaa gcaccgtact gtcggagtaa ctcctgtcgt tgccaaaaca
    10861 gccacaggtg ctattgaaca cgttccaatt gcccgagtga ccaacctcag tcaaacctta
    10921 gataaactta aggatgaagg tttctggacc tttggaacgg atatgaacgg tactccttgc
    10981 cacaagtgga atacaaaagg gaaaatcgcc ctcatcattg gaaatgaagg aaaaggtatc
    11041 tctagcaaca tcaaaaaaca ggtcgatgaa atgattacca ttccgatgaa tggacatgtt
    11101 caaagcctta atgccagtgt tgctgcggcc attctcatgt acgaagtttt ccgaaataga
    11161 ctataaaaaa gtttccagtc atctgattgg aaactttttt atgattaact atgttctgta
    11221 atgaatttat aggcttcttg accagcgata gctccatctc caaccgctgt tgttacttgg
    11281 cgaaggtctt tcaagcgaac atctccaact gcaaagatac cgtcgactgc agttttcatg
    11341 tggttatctg tcacaatcca tcctgcctga tcttggatat tcaattcttt aacaaaatcg
    11401 ctaagagggt ccaaaccaac atagataaag acaccaccga aggcttgttc tgtcacttga
    11461 cctgttttca cattttcaaa tacgactgat tctactcggt tttcaccctt gatttccctt
    11521 actacagaat cccagataaa gctgattttt tcattcgcaa aggcgcgatc ttgtaaaacc
    11581 ttttgggcac gaagttggtc acgacggtga acaatggtaa cagtcttagc aaaacgagtc
    11641 aagaagaggg cttcttcaac agctgaatct ccaccaccaa ctaccaataa atcttggtca
    11701 cggaagaaag caccatcaca cacagcacag taagaaacac cacgactgtt cagttcttct
    11761 tctccaggca ctcccaaagg acggtgttta gaaccagttg ctacgataac tgtacgtgtt
    11821 tcatatgttt ggtcatcagt catcactttc ttaaaatcac catggtcttc gacattttta
    11881 acataaccat aaatgtgctc aacaccaaga ttttcaagtg gttcaaacat cttttcagcc
    11941 aattcaggtc cactaatatt agcgtatcct gggtaatttt cgatatcaga tgtattattc
    12001 atctgaccac ctggcagacc accttcaatc aaagctactt ttagattgct tcgagcagca
    12061 tacaaggccg cagtcatccc tgcaggtcca gcaccgataa taatagtatc gtacatatag
    12121 attccttctt tcttgttgta actatcttta ttctaactct ttcttgtcaa tcacgcaagg
    12181 attatgcctt gaaaacaaga attaaactca taaccgcaaa ggataatact gggacaacca
    12241 agactccaat cataatcata tcatagagat gggcttggcg agccctggct gtcttatcaa
    12301 ctcccgacat ggctctcaga ccaatccaaa tccctaaaaa aatcagaaca aggatggtgg
    12361 tcaagatcaa actctcgaaa tataaagaaa atagttgcag tagcatgatt tctctcattt
    12421 ctatcttttt taaagagtaa actcagctag tccaactaac tgagttttcc tttatctatt
    12481 atatcaaata taagtccgtt tgtaactagc gaagaattct tttgtccgct cttctttagg
    12541 ggtgtggata atctcatccg gagttccaga ctcgatgatt ttccccttat ctaagaagag
    12601 aattttatcc gcaacttggg ctacaaagga catgtcatga ctgaccaaaa tcatggtctg
    12661 acctgactta gcagcatctg caatagactt ttctacttca ccgaccaatt ctgggtcaag
    12721 ggctgaagtt ggttcgtcta agagcaaaac atctggtttc atagcaagcg cacgcgctag
    12781 ggcaacccgt tgcttctgtc cacctgataa atggcgagga taatggtttt cacggtccga
    12841 aagcccaacc ttagccaact cttccttggc aatcttagtc gcttcttggt cagataattt
    12901 cttgacaaca accaagcctt ctttcacatt atcaagtgct gttcggcgtt caaataaatt
    12961 aaactgttgg aaaaccatag acaacttacg gcgtagggca aggatttctt cttgagtgat
    13021 tttagaaaaa tcaactgaaa aaccatcaat ctgaatagag ccactgtcag gtgtttcaag
    13081 ataattgaga ctgcgaagaa aggttgattt tccagctcct gaagaaccaa tcaaggctac
    13141 gacttctcct ttttgaatat ccaagttcag atgatccaag acagtctgtc ctgaaaagga
    13201 tttgcttaaa ttcgaaatct taatcattaa cgaaggtctc ctttcacatc tgtttgcact
    13261 gtatcaggtg cagaaatagc catttttctc tcgatgaaac gaccgaggct ttcaattccg
    13321 atattgacta cccaataaac aagggcaacg gagatgaagc gttcaaaata gcgataatca
    13381 gctccaccta gaatctgagc ttgggcaaag acttccacaa cacccgcact aaaagctaga
    13441 gatgttccct tggtcaaacc gatgagggaa ttaatcaagg ttggagtagc taccaccgct
    13501 gcattaggaa taatcactcg tcgataaact tgcgctcggg tcatacccag actgcgtgcc
    13561 gcctcaatct caccaggatt aactgagaga atggctgcac gaatggtttc actagcataa
    13621 gctgcctcat taaaggcaaa agcgacaatc gcaaaagctg cagctggaat cgcattgata
    13681 ttgagaccag ttccccattg ctgattgagg gctttcaaag ccaaagggat tccgtagtag
    13741 gtcaacatga gttgcaccaa aatcggtgtc ccttttaaga aactaacaaa gaaggcctgc
    13801 aagggatata aaatcttgac acgattgatc ttcacaatgg caaaaagaag cgccaaaacc
    13861 aagccaaaaa gggcaccacc aattgtcaac ataattgttg ttggaagttg ttggacaatt
    13921 ctagggattc catcaaagac cgaacgtagg ctaaacagct tgccatccgg aatcaattgc
    13981 atcaagtttt ggtaccaatc tgatgctaaa atcgttgtaa cattcataaa aacatcctct
    14041 tctgataatg attcattcta ccatgcttct gccgtcaatg aaattatttg ctacggtcag
    14101 atacagactt tgtctaccta ctagtttatc atactttgaa acagggaagt tatatatttt
    14161 atctatcaaa gagatagata aaaactattt cagtcccagt tcttcataag attttcgata
    14221 accgatttgc ttaacagttc cattttctac taaaatgggc cgttttaaca acataccgtc
    14281 acttgctagc aactcagccg cttcttggtt tgacaaactt cctaccttat cttttagccc
    14341 taattcacgg tatttgatac cactggtgtt gaaaaattgc ttcaattcaa atcctgaggt
    14401 ttctagccaa ttcaaaatga cttcttggct aggtgtttct tccacgatat ggacggcttt
    14461 atagtccaca cctaattgat ttaattcttg ttttgctttt ttacaagttg aacatttggg
    14521 gtattcgata aattctaaca tgtgcttctc cttctatttg tttatatctt taaaatctac
    14581 gccttcatgc tccaagagcc aagctttctt ttccactcct gcagcatagc ctgtcagacg
    14641 cttgcctgct cccaacacac gatgacaagg tactaggata gaccaaggat tgcgtcccac
    14701 tgctccacca attgcttgag cagaagccac ttgcaggtct tgagcaattt gtccataggt
    14761 cactgtctga ccataaggaa tgccctgtaa atagtcccaa actctctttt caaaattcgt
    14821 tccgattggc gccaagagca agttggataa atcctgaggc ttgcctttaa agtaatcatc
    14881 taagcaagca ataactgggt ctaaaatagg atgactaaca acttcttcta tcgtttcatc
    14941 tcctagtccc ctctcaaaat gcttctgctc ctgaacccaa attccataca aataatggtc
    15001 atcagctaca agtgatagaa taccaattgg tgaggagtag agtattttta catacttctt
    15061 ttgcattatt tctttaattt ttgataggcc aagcgttcgc catctactgg caccttacca
    15121 acttgtttaa aatcaagttt ttcaaaaata tgttgcataa ccttgttttc agcatgcgta
    15181 tctgagcgaa aatcaagata atcaaaacct tcaatcaagc cctctaagaa ggtttgagca
    15241 actccttttc cctgcacatc tgctgccaca gcaatacggt gaaagactag atactctgac
    15301 tctccagctt gccagtttcc ctcataaata gcttcatagg cctcctctgg actcttggtc
    15361 acagcagcat aggctagcag ttctccctct tccaaggcta cgtaggcttg ccctgagatg
    15421 atatcatcga taataacatc tgcatttgga tagccatttt gccactggtc actaccagca
    15481 tctgctaaac attttttggc atcctccatc acctgcatga tggcatctac ttcatttgga
    15541 aaagctaaac gaatttccat cttttttcct catttctgac tagtttctcc catcatagca
    15601 taatttaagt atttctacaa gcagttaaaa cttgactttg tgtttttgtt attttataat
    15661 ctagttatca aaactatata aaaaggagtt gaaaatgaaa actacctttt cctacccaaa
    15721 atgggcagaa attccaaaca ttgacctcta tctggaccag gttttgctct atgtcaatca
    15781 ggtctgcgcc cctatctctc ctaataaaga caagggccta acagcatcta tggtcaacaa
    15841 ttatgtgaaa aatggttacc tgacaaagcc tgacaaaaaa aaataccaac gccaacagat
    15901 tgcccgtttg attgctatca caaccctcaa gtctgtattt tctattcaag aaatagccca
    15961 gacacttaat actctacaaa ctcaagcaag ttcagaccaa ctctacgatg cttttgtgga
    16021 ctacatgaac caaggaattg acccagctaa ccctattatc caaaccagct gccaaaccat
    16081 taaactctat catcaaactc tagacttaat cgatcatact caagaggagg taatccaatg
    16141 aacactagtc ttaaactcag caaacaactc agttttggag aggagattgc taatagcgtg
    16201 acccatgctg tgggtgcagt catcatgctt atcttgctgc ctatttcatc catctatagt
    16261 tatgaagcac acggattttt atcctctatc ggcgtttcca ttttcgtcat cagtctcttt
    16321 ctcatgttcc tatcatccac catttatcac tctatggcct atggttcgac ccacaaatat
    16381 gttttgcgaa tcattgacca ttctatgatt tacgttgcca ttgccggctc atacacgccc
    16441 gttgtcttga ccttgatgaa taactggttt ggctatctga ttattgtcat ccaatgggga
    16501 acgaccatct ttggtattct ctataaaatc tttgctaaaa aggtcaatga gaaatttagc
    16561 cttgctcttt acctgattat gggctggttg gttctggcta tcattcctgc cattatcagt
    16621 caaacgacac ccgttttttg gagtctcatg gtaactggcg gactctgtta tacagttgga
    16681 gctggatttt atgccaagaa aaaaccttat ttccacatga tttggcatct ctttatccta
    16741 gctgcgtccg tactccaata catcgctatt gtttattaca tgtaaaaaag ttgagaaatt
    16801 caatctcaac ttttttcttt acacatattg ataaagtact ggtgcaagcg cacatcatca
    16861 gtcaattctg gatgaaaaga acttaccaac atattttttt cttgggctgc aacaatttga
    16921 ttgttcactg ttgctaaaat ttctacaccc tcaccaacac tactgataat cggaccacgg
    16981 ataaaggtca ttggaatctt gccaactccc ttacattctg cttccgtgta gaaacttcct
    17041 aattggcgcc cataagcatt acgctcgacc accatatcca tagttcctag atgactctct
    17101 ttctgagaag tgatttcctt agccagcaaa attaagcccg cacaggtccc aaacactggt
    17161 aagccagata gaatggcttc tcggatggga agtagcatgt tctggtcacg taagagcttg
    17221 cccatggttg tagactcacc accaggcaaa atcaaacccg acaagtcact ctgatcttgc
    17281 tgaaaatcat ctagatttct gagttctaca ctctcgacac ctaattgatc tagcactttt
    17341 gcatgttctg caaaggcccc ttgcaaggcc aatattccga ttttcatcta ttttcctcgt
    17401 tcagccatga gaatttggat ttcattttca ttaataccaa ccatggcttc tcctaaatct
    17461 tcagagattt gagctaggat ttgaggatta cggaagttag tcacagcctt aacaatggca
    17521 ctcgctcgtt taacaggatc tcctgacttg aaaatacctg aaccgacaaa gaccccctct
    17581 gcccctaatt gcatcattaa cgcagcatct gctggcgttg caacacctcc agcagcgaaa
    17641 tttacaactg gcaattttcc atgttcatga acatattgga ccaattctac agggacttgc
    17701 aaatccttgg cagcaacata aagctcgtcc tcacgtaagt tttgaatgcg gcgaatttcc
    17761 tgattcatca tacgcatatg acgaacagct tggactatat cccctgtccc tggttctcct
    17821 ttggtacgaa tcatggaagc accttcagcg atacgacgca aggcttcacc caaatcctta
    17881 gcaccacaga caaaaggaac ttggaattct ttcttgtcca catggaaacg gtcatcagct
    17941 ggagatagaa cttcactctc gtcgatataa tcaatttcaa tagcctctaa aatctgagct
    18001 tcaacaaaat gcccgattct gaccttagcc attactggaa tactaaccgc ttcttggatt
    18061 tccttaatca tctttgggtc gctcatgcgg gaaactcctc cagctgcacg aatatcagcc
    18121 ggaattcgtt ccaaggccat cacagctgcc gcaccagcag cttctgcgat acgagcctgt
    18181 tcaggattct gcacatccat aataacacca cccttgagca tctgtgccaa atttttattt
    18241 agttcataac gattttcagt catttgtttt atcctcatca tttgtattgg tagctacctt
    18301 ttcattttaa gtcagaacag aatgaagcac aagataaaaa aactataatt gtatggggac
    18361 aaattagcta aaaactatct gaccttaact taaggccaga tagctcattc atttttattt
    18421 ttcagccgta agggcagcca ttgtgatgta gttgtatggt ttgttgaagt gtggcaagaa
    18481 gaagaggtct gtcaatgcca atttatcaat tgtcacatgc tcttggatag caagtgagaa
    18541 catgtggatt cccatgctaa ttgcaatatc atgtgaaacc atttgggcac caagaatttc
    18601 acggctatct ttgtcaaaga caatcttaat tgctacttca tggttgtcat gtttcatgaa
    18661 ttctggtttt tgaagatcgt taaagcctgt ttcagttgcg ttgtaaccag cagctttcgc
    18721 tttttcaaga gtcaaaccag ttgaaaccat gtgaagaccg tagattgaga taccatttga
    18781 accttgaaca ccgattcctt ccaattcatg tccacaagcg ttgtaggcac caacgatacc
    18841 agtgcgaaca gcatttgaag caagagcgat atagcttgta tctttacgag cattgtcata
    18901 aacagtcgca cagtcaccaa cagcgtaaac gcctgggata gatgtttctt gtttcttgtc
    18961 tacaaggaag gcaccgttgc ggaagagttc gatcttacca tctgcaaggg ctgtgtttgg
    19021 acggaaacca actgcaagga taaccatatc cacgtcaaag ctttctttgt cagtaatcaa
    19081 gcgttcaact ttaccgtcac cttcgattgc tttaacagtt tgacctagag ccaagcggat
    19141 gttgtgatct tccaagttct tcgccatcat ttgtgtgaag tctttgtcat agtaaccgtt
    19201 caagacaata tcaacgatat caacaaggac aacttctttt ccaagacgtt caaaggcctc
    19261 agcaagttca acaccgatgt aaccaccacc aacaacggcg atacggtcga ggtgttggct
    19321 cttgtcagaa agtttattga taacttcttc agcattttgg tacaatttca cgaattgtac
    19381 gttttcaaga gttgctttaa attcgcggtt tcctttaaca atttcaacac cttcgattgg
    19441 tggcaagatt ggtgtagaac ctgtagcgaa aatcaatttt tcgtatgatt ctttgtgctc
    19501 ttttccttca acttccgctg taactacttt gttatcatag tcgattgaaa gaacaggtga
    19561 gttcatgtaa actttagcac ctttagcttc caatttttct ttatcagaat agaacaagcc
    19621 ttcagcaccg tcaatttgtt caccaatcca aagagccatt ccacatccta ggaaagagat
    19681 gttagagttt tggtcaaata caacaatttc gttctcattt ccaaaattat ccaacatggt
    19741 attgatacat gctgtaccag cgtggttagc accgactaca acgattttac tcataaaaaa
    19801 tttcctgcct tcattctaaa tttaccttac tagtatacca tttaccgtta gcgtttacaa
    19861 ggggggtact atcatttcag cattttttat caaaaataat tccccattta tcctgttttc
    19921 aagcctgatg aattttatga gcatatttct tgactttttc caaattttgt ttgtgaaaat
    19981 tctaacttta tggtattata ataacatgaa aatgaaatgt aagggcttca atttagatga
    20041 ttatttgata ttacaactta ttttctataa gagaaaggag ttggtagctt gactcttcgt
    20101 tcacattctg aacggctaat ggggactact atcactattt cattagtgga tgagcaagcc
    20161 gatatctttc tccaaaaatc ctttgacttg ctcaaagaac ttgaataccg cttcaacgcc
    20221 aatagtcaag aatctgagtt gatggaaatc aattatcaag caggaatagc ccccgtcacg
    20281 gttcatccag acctgtttga gctgatttca cttgggttag agcatagcct agcgctctct
    20341 agccacctca atatcagcat tggtccctta attcaaacct ggcgtatcgg tttttcagat
    20401 gccaaggtcg cccagcctca agaaattgaa tcggtgctgc ctctaatcaa tcctcatggt
    20461 atcaagttag attcttctac ttctactgtg tttttaaaac agaaaggaat gaagatcgat
    20521 ctaggttgtt tagccaaagg atacagtgcg gataaggttg cccaatttct taggaaagag
    20581 ggggtgactt ctgccttgat caatctggga gggaatatcc tgaccattgg aaaaaatcag
    20641 gcaagagggg ataacccatg gcaaatcggg attcaagacc cagccaatcc taggggaaat
    20701 catttaatga ccatccctgt tgtcaataaa tctgtcgtga cttcaggcat ttatgaacgt
    20761 cacctgaccg tcgatggaca agattaccat cacatttttg acagtcaaac aggatatcct
    20821 gttgaaacgg aactagcgag tctaacaatc atctctgata aatcagtcga tggcgaaatc
    20881 tggacgactc gactctttgg agaaagacct gcttctatcc tctggcaagt cgaaagtttg
    20941 gagggcatcg aagtcatcct catcgataaa gaaggccacc taagctgttc ttcaggaatt
    21001 cctactctat agagacaact gtttcaatgg aattttaaaa ttgtattatg taaaaagaga
    21061 aaggaaatct catgttaaaa cttattgcta ttgttggaac aaattcaaaa tgttctacaa
    21121 accgtcaatt gcttcaatac atgcaaaaac actttactga caaagctgaa attgagcttg
    21181 ttgaaatcaa ggccattcct gtcttcaaca aaccagctga caagcaagta cctgctgaaa
    21241 tattggaaat tgctgctaaa atcgaagagg ctgatggcgt tattatcggt actcctgagt
    21301 atgatcactc tattccagct gttttgatga gcgctcttgc ttggttgtct tatggtattt
    21361 acccactttt gaacaaacca atcatgatta caggtgcttc ttacggtacg cttggttcat
    21421 ctcgtgccca attgcaactt cgtcaaatct tgaatgctcc tgaaatcaag gcaaatgttc
    21481 ttccagatga attcttgctc tcacactctc ttcaagcatt taacccaagt ggcgacttgg
    21541 ttgaccttga tgttatcaag aaattggatg ccatctttga tgacttccgt atctttgtaa
    21601 aaatcacaga aaaattacgt aatgcacaag aattacttcg caaagatgct gaagactttg
    21661 actgggaaaa tttgtaagat aggagaccaa aaagaatgaa atttgttgga cttgttggat
    21721 caaactacga tcaatcatat aaccgtaagc tcttggaatt tatccgtcgc tacttcaaac
    21781 tcaaatttga attagaagtt cttgaaattg acgaagttcc aatgtttaac caagatgaaa
    21841 aatgggatga aagtttccaa ttacgtttct tgtataacaa gattacacgt gctgatggtg
    21901 tcattatcgc cactcctgag cacaaccaca ctatctcagc ttcactcaaa tctgtacttg
    21961 aatggctttc atacgaagtt catccatttg aaaacaagcc tgttatgatt gtgggtgcat
    22021 catactatga ccaaggaaca tcacgtgctc aagttcacct tcgtaaaatc cttgatgctc
    22081 caggtgttaa tgcctacacg cttccaggta acgaattcct tcttggtaaa gctaaggaag
    22141 cttttgataa caacggaaat atcaccaacg aaggcactgt taaattcctt gaaacttgct
    22201 tagataactt tgttaaatac gtaggagtcg tttcgaaatt gaaaaaacca aaaccaatcg
    22261 aatcagaaga cttagattgt ggaaaaccaa tcgctacaac catcacagaa gttgaccctg
    22321 acgatccaga atgggtagaa aaagttgcag caatcactgg tgctgtttct ggtgatacct
    22381 atgtcaaatt ggaccacggt atcctaacag ttaaccaaat tgatatgttc ttgaaagcta
    22441 tgccatttga attgacatac gctgacgaca acaaccaatt cctctactac aacaacgctc
    22501 accaagatcc agacactatg ttcgctaaac gtgtaccacc tcaatcaggt agccgtatgt
    22561 cgactgttca tggttctctt ccaccagcac gtatgaagaa cgtagagtgg gttatcggaa
    22621 cacttcgcaa cggaaaccaa gaatacgtcc gtacgatcgt tccaggttct cctgcaggtg
    22681 ttatcaacac tcacaactac caagcaatgt actatcctga tggatcatac gctggtatca
    22741 atgaaatcgt ctttaacttc caaccatggc ttgactggta cctaaaagag actggtcaac
    22801 gtttggtggg tggtagcgga ccatttgctc ctgctgccgg agatcatgga gacgccgatg
    22861 ctacttctgg cgcttctgat tcaggggatg ctggaggcca cggtggtgac gcagacgcta
    22921 cagccggtgc aagttactaa tgatagtttt taggaaccat tatggttcct tttttagcga
    22981 aaaaagacta acaaacacaa actgctagtc tctttgttat cgtttcatct atccttgtca
    23041 aaagaaagaa tacttatact caatgaaaat caaagagcaa actaggaagc tagccgcagg
    23101 ctgtacttaa gtacggcaag gtgaagctga cgtggtttga atttgatttt cgaagagtat
    23161 tattatgaat ttgggtcatc aagactacgg ccatgtaatc ctttttcacg ttgtacttgg
    23221 cgtagttttt ctggtgtaac atcgtttcct tcttcgtcca caattttgat tccttcaatg
    23281 tggtgacgaa cagcgcggcg ataaccttcg atgtactcct cacgtagttt ggcttgttcc
    23341 actttttctt ctggtgttaa gccttctgtt tttttctttt tagcaagctc attgatacga
    23401 gcaatttttt tcggatccat ttcttctcct ttgtaataag ataaagtccg tttatcaaat
    23461 tttatttagt gttaatttgg ttaaaacaag caaacttagc tgctttcttg gttagttgtg
    23521 acaagattgc caaacgattt tgacggacag cctgatcttc agccattacc atagtatttt
    23581 caaagaaagc atcaatgact gggctaagcg caaagagttg tttcaattgc tgacttgcag
    23641 gtcctgataa aacgagtgtt tctacttctt ctgccaaagc tttttcttgg tcattctcaa
    23701 atagtgctga atcaactgta gcaacccctt ctgccttctc agccaggtta aaggcacgag
    23761 aaagtgattc aacagatggt ttaaaatctt cttccttgct tacttctacg agagcacttg
    23821 ctgcttccaa catatctgcc acaacaaagt ttgaacctgc aagaactgct tccttgatat
    23881 cttttggagt agagcccatc atcttatcaa cacgagcctt gataaagtcc ataacctctg
    23941 ctttattttc ataagtcaaa ctgtcaaatt tcaatgcata aaggctatca atcagctcat
    24001 ccatagcaat gtgccaacca aaggcatcca agatacgaac cacaccttga gttgcacgac
    24061 gaagggcata agggtcatta gaacctgatg gaatcaatcc tactgagaag aaactcaaaa
    24121 tcgtatccaa tttgtctgca atggctagaa ctgcgccgac cttgctctct ggaagttctc
    24181 cttcagctga tgtaggcatg tagtgttcac gaatagcagc tgccaccgct ggagtttcac
    24241 cagcaagaag ggtgtatttt tcacccataa ttccttggag ttcgtcaaat tcaccaacca
    24301 tacctgtcaa caagtcaaac ttgtaaatgg ctgctgcacg agcaaggtca actgtttcat
    24361 ccactgacaa accagctttt tctgccaaaa gtacagtgat ttgacccgta cgaatcatgt
    24421 gttcacgaag ggaaccaatc ttctcatgga aggtgacatt gtttaatttt tcaacaagat
    24481 ctgaaatcac caatttttgg tcttcacgcc agaagaattc tccgtcttcc aagcgggcta
    24541 ccaagacttt ttcatttcct ttaatgacat ttttcaaacg ctctgcgttt ccgttacgaa
    24601 cagaaatgaa gtttggcaag agttttccat cttgatcacg aacaacaaag taacgctggt
    24661 gttccttcat agaagtcacc aagacttctt ctggaacttc aaggtattta gcatcaaaac
    24721 ttcccatgaa ggcagttggg tattcaacca aattcaagac ttcattcagc aaatccgcat
    24781 caatttcgat acgtacacca tgttttgcct caatttcctt gatttggtca acaatcattt
    24841 gctcacgttc acatggatct gcgattacaa actgcttacg aaggtcttct tcatagctca
    24901 atgctgactg aattttggtt tctttcccca agaaacgatg gccacggctc acacgacttc
    24961 ccttgatatc aaggaaatcc aagtcaaact cttgctcatc caagagaaca gttaaagtgt
    25021 gaacagggcg gatgtattca aagctatttc ccgcccagtg catgctgaca gggaaagtca
    25081 gtgacttcaa gacatccaca atgcctggaa caatggcttc aactgcttga ccaatttctt
    25141 ccttagtgac atagacatat tcttcaccct tgatttcacg gaattcgata tcttcaacag
    25201 tcaaaccttt cccacggaca aatccttgag ctgctttggt gaagtttcca tcactatcta
    25261 aggcaatttt ctttgctgga cccttgaaat cttctgttaa atcagactgt ttgtctgcaa
    25321 gaccagttac acgaacagcc aaacgacgtg gtgttgagaa agtttgaatg gcttcaaaag
    25381 acaggcgttt tcccttgagg aaggctgcca ttttttcgcc tagttgtttt tcacttggcg
    25441 taacaacata ggctggtaat tcttcaagac cgagttctac taataagttt tttgtcatgt
    25501 tttttccttt acattttctt caatcttttt tgatatgcac cttaggtact ggggacgtcg
    25561 ctaactaact ctgtgagtct gtatggaaat ccaatgctaa atttatcaag atttccaaca
    25621 atctcatcaa agtggattta gctgactgat ttttgaacct aaggtttcaa aaatccccac
    25681 ataacagtac agcggtgcat atccctctag caagtcttcg acttgcctct aacgatttta
    25741 gagtacagta ttactcacta ttctgagtct tctgctaaaa gtttaactcg tgtttcttca
    25801 tccaaaagtg ggtaacctag gcgtttgcgt tctgcaacaa aggttttggc tacaacacgg
    25861 gccaagttac ggatacgagc gatatagcct gcacgctctg ttacagatac ggcaccacgc
    25921 gcgtcaagca gattaaaggt atgtgaacat ttgagaacat agtcataggc agggtgtacc
    25981 aagccttctt ctaatgcacg accagcttct ttttcaaact tatcaaaatt ttcaagcaac
    26041 atttcttggt ccgaaatttc aaatgaatat tttgagtgct catactcagg ctggataaag
    26101 atttctccgt attttacacc atcagcccac tcgatatcat agacagagtc tacttcttga
    26161 atgtaagaag ccaagcgctc caaaccatag gtaacttccg cagtcacagg gctagttgcc
    26221 aatccaccga cttgttggaa ataagtgaac tgagtgattt ccattccgtc aagccaaact
    26281 tcccaaccaa gaccagctga accagttgat gggttttccc agttgtcctc aacaaaacga
    26341 atatcgtgct ccaaaggatt gattcccaat ttttccaaag actcaaggta aagttcttgg
    26401 atatttgatg gagaaggctt catgaccacc tggaattggt ggtgttggta gagacggtta
    26461 gggttttccc cataacgacc gtcagcagga cgacgtgatg gctctacata agctgcattc
    26521 catggctcag gtccgatagc acgaaggaaa gtgtaaggac tcattgttcc cgcacctttt
    26581 tcattatcat aagcctgcat aagcatacaa ccttggtcat tccaaaattg ttgcaaagta
    26641 aggatgattt cctggaaagt caatttctta gacattgttt actcctttag tttttatatt
    26701 tctttttcaa ttaatttctg ctgaacaaac caatctaaca agggaaaagt tttttctgta
    26761 tttgcccata aatgataaga atctaagacc gcttgtacac tacctaaatt ttctaccaac
    26821 ttatctactg tcaaaaagct gcgccagtat tcataaaaaa tacttgcata gttcttatca
    26881 taagtcgaag aaccaaaatc attcaatgaa tgccaaccat acttcttctg aaaaagttct
    26941 acgagagatt gattacaaat tttttccgct tgaaattcct cttctgtcaa gaaatacttg
    27001 cgactaatat attcaaccat cccctcttcg aaccagatat aagagtcata accatcaaaa
    27061 tcatctaaaa aatgctccga ccaatgagct aactcatgtc ctacaatctg taagaggaaa
    27121 ttttcagata aagaatgata gtgactttct attgcttgag tttgctcaga acactcgtag
    27181 tccatcaatt gatacaaata caactctttc caaacagcta aatcaggcgc cataaccatt
    27241 cgtctattat ttgtataggc tggaacagcg ctttccctaa taatctgtgt agcagcatta
    27301 aaatctgacc aaataacggc ttgcggtaaa tcacagactg caagttcatt ctttaaaaaa
    27361 gattgataat ctttcaactt ttcagtattt cttactacaa aatcacgaaa tgtagctagt
    27421 tgactatcgt cttttacaag ataaaggttg tccacggctc tcctttcttt cacacaatag
    27481 actgaataag caaaagaacc acatctgaca atcctaggtt gatttaacct aggggcgtca
    27541 gaaacgcggt tccaccctaa tttattactt cattgttttt gaaaatacta cagaaagcgc
    27601 cagctcatta ttttgcccta cttggctccc actgtcccaa gctcgcttga agaacgccat
    27661 aagactttct ttcctgctga ctattatatc aaaaattaga ataatgtaca attcttttta
    27721 tgattttcta aaaatccata tcatcagctc gtggagcacc agaatgaaca gctatcgttt
    27781 ttaaggtttc atgttcctca tggctcaatt caattccaaa gcaatcaaga ttagcctgaa
    27841 tacgagatgc tgtaacagat ttcggaagtg gtaaaaatcc ttctgccaag ctccaggcca
    27901 aggctatctg agcaacagac tttccatgat ttgctgcgat ttcttggact tccttactat
    27961 caaatagttc tccctgacca aaaggtcccc aagcttccaa taaaattcct ttttctctac
    28021 agtaagctac gacttcctct tgatacacac ctggtgccaa gcgaacctga ttgaccgcag
    28081 gaacgatagt tgcagttgca agcaaggcat ccaaatgatg gggaagaaaa ttgctaacac
    28141 cgatagcacg gattttccct tcttgataga ggtcttccat cgctctccaa acttccgcat
    28201 ttcggatttt ccattggtca ttttctctaa gcggttttgg gttcggccaa tgaatcaaat
    28261 acaaatccaa ataatccaaa cccagcttct ctaaagactc tgcaaaagcc tgacgagctt
    28321 gctcataggt ttgctgacta ttccaaagct tggtagttac gaacaaatcc tctcgtggaa
    28381 ctccgctatc tttgattgct tggccaacac tttcttcatt ctgataaatc gctgccgtat
    28441 caatatgacg ataaccagcc ttcaaggctt ctaacactgc acgataggct tcttctccat
    28501 ccttagcctt aaaagttcca aatcccaata ctggaatttt tactccatta tttaattgat
    28561 aggtattcat atgcttctcc ttctctttta tttatcattt atagcataaa acatttttta
    28621 agtagtacta tcttctgtaa aaaataagtc tatcacatat ctgacagacc tattttttct
    28681 tgcttattca tcacgactat aatacagttc atgaggtttt aggcgagtat tgagcatctc
    28741 tggtatggtc acaaaggtat aaccttgatt tttcaaatac tcaatgaccc ttggcaaggc
    28801 attgactgtc ggactgtgaa tatcatgcat caaaacgata gaaccattag ctacttgatg
    28861 ctgaatttcc gtcaaaatag atgcttcatt tttactcttc cagtccagac tatccacatc
    28921 ccacatgata aagctcaaat ccaagctatt gcgaatatca tctgtaatgg ctccataagg
    28981 cgggcgcatg agttttgaac tagaacccag cactttagtt agcacatcct cagtatcagt
    29041 aatctgcttt ttagcttcat caagagaaag ttgcgagaga atcggatggc tccaactatg
    29101 gtttccaaca acatgacctt cagattttat cctcttcacc aagtcctcat tcccagaaac
    29161 atttttccca agcacaaaga aagtcgcttt aatatcatat ttagctaggg tctctaatac
    29221 ctgcggggtc gttgctggat ttggaccatc atcaaaggtt agagcgacaa ctttttgata
    29281 tttcttatca aagtaagatt ggtacaaggc cgcatctttt tcgagtaagt acgaagattg
    29341 gataacatca aagaaagcag atactggcaa ggctatctct tctaaatttt caaccacagg
    29401 acttggataa aggataatct gactatcctt gtaatcaaaa ttccatgcag acaagtcttg
    29461 gtcggagaag ttttttacaa tctgctcact ctggtcttgc tctatttttt tatcctctat
    29521 gaaggaggtc aactctttta tcagctgttc cttagcctta ctagcatctg aaaacagttg
    29581 gtcaagtgta aaaggttgcc catcttctgt taagtgaacc tttcctagac tggtcttttc
    29641 agtctcttca accttaaaag caactaaatc atagatttgt ttggtcacat tacgattaac
    29701 gactcccttt aaacctgact cttcttgctc tgtatagtag aaaacaagat tgtccttact
    29761 ttctagcttg tccttaacat cttgatttat caactcccta acagaggaaa tcactttctc
    29821 cccttggaga ggataatagg caatcacttc ggcttgcccc tgacgaaaat gctccttctg
    29881 atttccctca ctcaattgat catctttctc ttttttgagc gattcaatct tttgctcaaa
    29941 acttttttgc tggtagatct taaaagcaat aaatccgcct aataggcaaa tagaaattgc
    30001 taaaatacca atcaaagcca ataatacatg tctcgttttc ccgtgtctgc cacgtcctag
    30061 tctactttta ttcatattta tatcataaca aatttgagca ataatttcaa tgatacaatt
    30121 tggcaatcca caattcctct agcaagccaa agcatcttac atcaactcca acatccgtat
    30181 ctgtagagat tatgtagttt tctatctatg gaatttctag tagattgaag ctagaatagt
    30241 agacctatac ttctaaaaca ttgttagaaa tcgatttgat tgtcctgatc gatttgtcct
    30301 gttctcattt cattttacta taaaactatg aaaagctagg tcatctgaga agtaattact
    30361 atcgacaatt gcgatagcgt atactggtgc gatttgtttg tagctctggt gggtatcacc
    30421 ttcacgttgg cgaatttttt ctaggttttg attaacctga ctgcacagat aagcccatag
    30481 gcgattgatg aaaaaattct gatgatgaac ctgaatttcg atgataactt ggattccatt
    30541 atctaactcc gccaagacgt ctatactagt atagaaatcc tgcgctgagt agggcatgga
    30601 aggcaagacg tgaatgttac ttccctccaa aatcgtcaca ttttttgctg gcaagtccag
    30661 catatcgcgg ataaattgac aaatcattag ttgggctgat acccggatgt ctgagaatcc
    30721 tccttttcct ccttctatta tagcacattt ttaaatctag gtttgctaga ttctatgctt
    30781 ctatctattt attcggaaaa gaaagctaat agcttatttg aaattttctc ctctctgttg
    30841 gatagtcccg tctatctatg ttataatgaa agaaggattt aaaatcggaa aaggagtatt
    30901 tatgctaaaa ttaggtgtca tcggaactgg cgctatcagc catcatttca tagaagcagc
    30961 ccataccagt ggagaatacc aactggtcgc aatctattct agaaaactag aaactgcagc
    31021 aacctttgct tctcgctatc agaatatcca actattcgat caattagaag tcttcttcaa
    31081 atcttctttt gatttagtct atatcgccag tccaaactcc ttacattttg ctcaggcaaa
    31141 agctgccttg tctgctggta aacatgttat tctcgaaaag ccagctgtca ctcaaccaca
    31201 agaatggttt gatttgattc aaacagctga aaaaaataac tgttttatct ttgaagcagc
    31261 tcgtaattac cacgagaaag cctttactac tatcaaaaac tttttagcag ataagcaagt
    31321 gttaggagca gatttcaact atgccaaata ctcttccaag atgcctgact tgttgactgg
    31381 acaaacacca aatgtctttt caaaccgttt tgctggtgga gccctcatgg atttggggat
    31441 ttatcccctc tatgctgctg ttcgtctttt tggaaaagcc aatgacgcga cttaccatgc
    31501 tcaacagctt gacaatagca ttgacctaaa tggagatggt atcctcttct acccagacta
    31561 tcaagttcac atcaaggctg gaaaaaacat cacttccaat cttccttgcg agatttatac
    31621 aacagatgga accttgactc tcaacacgat tgagcatatt cgctcagcta tttttaccga
    31681 ccaccaagga aatcaagtcc agcttcctat ccaacagact cctcatacga tgactgagga
    31741 agtcgctgca tttgcacaca tgatccagca accagatctg aatctctacc aaacttggct
    31801 gtatgatgca ggctctgttc atgagctact atataccatg cgccagactg ctggcattag
    31861 atttgaggca gaaaaatgaa aaccaaacta ccgactgaat ggcaagaact gagtgaccaa
    31921 ctcggtttcc aagaattcac ccccattcaa actcaactat ttgagcccct tcttgctgga
    31981 gaaaacctcc taggagtgag ccaaaccgga actggtaaga ccctagcgta tctcctacca
    32041 agtcttctca gactacaaaa gaaaaaagcc caacaactct tgattctagc accaaacacg
    32101 gaacttgctg gacagatttt tgatgtatgt aaaacgtggg cagaagctat cggattgact
    32161 gctcaactct tcctttcagg ttcaagtcag aaacgacaaa ttgaacgcct taaaaagggg
    32221 ccagaaattc tgattggaac tcctggccgt atctttgaac tcattaaact taaaaaaatc
    32281 aagatgatga atgtggaaac catcatcctg gatgaatttg accaattact agatgattct
    32341 cagattcact ttgtagaaaa aatcactcac tacgcacctc gtgaccacca actggtctac
    32401 atgagtgcca cgaccaagtt tgatcaagaa aagattgtgc cgaatacacg cactattgat
    32461 ctctctgatc aaaaattgga caatatccag catttctaca tgcaggtaga ccaacgtcat
    32521 cgagtggata tactacgaaa actggctcat gtagaggatt tccgtggtct agtcttcttc
    32581 aatagcctgt cagaccttgg gaatgccgag gaaaaactac agtatcgtga tatattggct
    32641 gtttccctcg ctagtgatgt taatgttaaa tttagaaaag tcatcttaga aaagtttaaa
    32701 gataaccaac taaccctgct tcttgcaact gaccttttgg ctcgtggaat tgatatcgat
    32761 agcctagaat gtgtcgtaaa ctttgatatt cctagagata gcgaaaccta cacacaccgt
    32821 gctggccgta ctggccgtat gggcaaggaa ggatatgtta ttactctcgt cactcatcca
    32881 gaagaaatca aaaaacttaa aaagtttgca agtatccgag aaattgtcct aaaaaaccaa
    32941 gaactctata tcaaataaag ccccattgct ctatacacat ccagtgtatg gagctttttt
    33001 ataagcaatt caattttata ctcatctgct ttcaaaaagc attctattcc atctccgatt
    33061 aacgatggac tttatcacct ccttctccag tccttgtatg acatcttgga gttgattcat
    33121 gacatcttcc aaagttcgaa aggctttatt cttaaatcca cgtttacg
//
LOCUS       DAVHTH010000020        33005 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.020, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000020 DAVHTH010000000
VERSION     DAVHTH010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33005)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33005)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33005
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.020"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            complement(43..840)
                     /gene="psrA"
                     /locus_tag="VVR63_000977"
     CDS             complement(43..840)
                     /gene="psrA"
                     /locus_tag="VVR63_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type DNA invertase PsrA"
                     /protein_id="HEU6129006.1"
                     /translation="MKDFELHLKKAGLAENTVRSYLYGVRFFLENYELKMEDLFEYKG
                     YLLDNFKPKTVNLRLQGVNKYLAFIGHDDLKLKFVKVQQKPFLEDVISHADYLFLKRS
                     LKKDGILKWHFVVWFLGATGARVSELIKLKVEHVEIGYFDIYSKGGKIRRLYIPKKLR
                     NSCLSWLESENRRSGYLFLNKFNEPITARGVAQQLKNYADKYKMNPKVIYPHSFRHLF
                     AKNFLAKYNDIALLADLMGHESIETTRIYLRKTATEQQNIVDKIVNW"
     gene            complement(897..2216)
                     /locus_tag="VVR63_000978"
     CDS             complement(897..2216)
                     /locus_tag="VVR63_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU6129007.1"
                     /translation="MPDTWEWVRFSTLVEIVRGGSPRPIKDYLTSEVDGINWIKIGDT
                     EKGEKYINNVKEKIKKSGLNKTRFVKKGTFLLTNSMSFGRPYILNVDGAIHDGWLAIS
                     NYENSLNKDYLFYILSSNVVYSQFLSLISGAVVKNLNSDKVASILIPLPPLSEQQRII
                     EAIESALEKVDEYAESYNRLEQLDKEFPDKLKKSILQYAMQGKLVEQDPNDESVEVLL
                     EKIRAEKQKLFEEGKIKKKDLDISIVSQGDDNSYYEEVPCEIPESWEWVRLNDITSYI
                     QRGKSPKYSNIPIYPVIAQKCNQWSGFSIDLARFIDPETVHSYQKERLLRDGDLMWNS
                     TGLGTLGRLAIYHENKNPYGWAVADSHVTVIRVLSGVINCHFIYNFLSSPIVQSVIEE
                     KASGSTKQKELLTKTIKEYLIPLPPLPEQSRIVDKIEQFFAHIDALI"
     gene            2761..2880
                     /locus_tag="VVR63_000979"
     CDS             2761..2880
                     /locus_tag="VVR63_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HEU6129008.1"
                     /translation="MPDIVFEIEFFHSDSLIFFYTSDDKSNSQKSQEDFSKNK"
     gene            complement(2976..4322)
                     /gene="glnA"
                     /locus_tag="VVR63_000980"
     CDS             complement(2976..4322)
                     /gene="glnA"
                     /locus_tag="VVR63_000980"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HEU6129009.1"
                     /translation="MPITAADIRREVKEKNVTFIRLMFSDILGTMKNVEIPATDEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWTVFPWGDENGSVAGLICDVYTTEG
                     EPFAGDPRGNLKRALRHMEEVGFKSFNLGPEPEFFLFKLDENGDPTLEVNDKGGYFDL
                     APTDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYDEVLRACDKIQIFKLV
                     VKTIARKHGLYATFMAKPKFGIAGSGMHCNMSLFDAEGNNAFFDPNDPKGMQLSETAY
                     HFLGGLIKHAYNYTAIMNPTVNSYKRLVPGYEAPVYIAWAGRNRSPLVRVPASRGMGT
                     RLELRSVDPMANPYVAMAVLLEVGLYGIENKIEAPAPIEENIYIMTAEERKEAGITDL
                     PSTLHNALKALTEDEVVKAALGDHIYTSFLEAKRIEWASYATFVSQWEIDNYLDLY"
     gene            complement(4359..4715)
                     /gene="glnR"
                     /locus_tag="VVR63_000981"
     CDS             complement(4359..4715)
                     /gene="glnR"
                     /locus_tag="VVR63_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000659547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor GlnR"
                     /protein_id="HEU6129010.1"
                     /translation="MKEKEFRRNMAVFPIGSVMKLTDLSARQIRYYENQELIKPDRNE
                     GNRRMYSLNDMDRLLEIKDYISEGYNIAAIKKKYAEREAKSKKAVSQTEVRRALHNEL
                     LQQGRFASVQSPFGRG"
     gene            complement(4792..5319)
                     /locus_tag="VVR63_000982"
     CDS             complement(4792..5319)
                     /locus_tag="VVR63_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEU6129011.1"
                     /translation="MSYFKKYKFDKSQFKLGMRTFKTGIAVFLVLLIFGFFGWKGLQI
                     GALTAVFSLRESFDESVHFGTSRILGNSIGGLYALVFFLLNTFFHEAFWVTLVVVPIC
                     TMLTIMTNVAMNNKAGVIGGVAAMLIITLSIPSGETILYVFVRVLETFMGVFVAIIVN
                     YDIDRIRLFLEKKEK"
     gene            complement(5455..6651)
                     /locus_tag="VVR63_000983"
     CDS             complement(5455..6651)
                     /locus_tag="VVR63_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HEU6129012.1"
                     /translation="MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYIIEQGGRAILFSHLGRVKEEADKAGKSLAPVAADLAAKLGQDVVFPGVTRGAELEA
                     AINALEDGQVLLVENTRYEDVDGKKESKNDPELGKYWASLGDGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKALLEKANGKLILPVDSKEANAF
                     AGYTEVRDTEGEAVSEGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQAG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGL
                     AALTEK"
     gene            complement(6741..11651)
                     /locus_tag="VVR63_000984"
     CDS             complement(6741..11651)
                     /locus_tag="VVR63_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HEU6129013.1"
                     /translation="MKNPFFERRCRYSIRKLSVGACSLMIGAVLFAGPALAEETAVPE
                     NSGANTELVSGESEHSTNEADKQNEGEHARENKLEKAEAASAAKPEEKAGEVVAETPS
                     AEAKPKSDKETEAKPEATNQGDESKPAAEANKTEKEVQPDVPKNTEKTLKPKEIKFNS
                     WEELLKWEPGAREDDAINRGSVVLASRRTGHLVNEKASKEAKVQALSNTNSKAKDHAS
                     VGGEEFKAYAFDYWQYLDSMVFWEGLVPTPDVIDAGHRNGVPVYGTLFFNWSNSIADQ
                     ERFAEALKQDADGSFPIARKLVDMAKYYGYDGYFINQETTGDLVKPLGEKMRQFMLYS
                     KEYAAKVNHPIKYSWYDAMTYNYGRYHQDGLGEYNYQFMQPEGDKVPADNFFANFNWD
                     KAKNDYTIATANWIGRNPYDVFAGLELQQGGSYKTKVKWNDILDENGKLRLSLGLFAP
                     DTITSLGKTGEDYHKNEDIFFTGYQGDPTGQKPGDKDWYGIANLVADRTPAVGNTFTT
                     SFNTGHGKKWFVDGKVSKDSEWNYRSVSGVLPTWRWWQTSTGEKLRAEYDFTDAYNGG
                     NSLKFSGDVAGKTDQDVRLYSTKLEVTEKTKLRVAHKGGKGSKVYMAFSTTPDYKFDD
                     ADAWKELTLSDNWTNEEFDLSSLAGKTIYAVKLFFEHEGAVKDYQFNLGQLTISDNHQ
                     EPQSPTSFSVVKQSLKNAQEAEAVVQFKGNKDADFYEVYEKDGDSWKLLTGSSSTTIY
                     LPKVSRSASAQGTTQELKVVAVGKNGVRSEAATTTFEWGMTVQDTSLPRPLAENIVPG
                     ATVIGSTFPDTEGGEGIEGMLNGTITSLSDKWSSAQLSGSVDIRLTKPRTVVRWVMDH
                     AGAGGESVNDGLMNTKDFDLYYKDADGEWKLAKEVRGNKAHVTDITLDKPITAQDWRL
                     NVVTSDNGTPWKAIRIYNWKMYEKLDTESVNIPMAKAAARSLGNNKVQVGFADVPAGA
                     TITVYDNPNSQTPLATLKSEVGGDLASAPLDLTNQSGLLYYRTQLPGKEISNVLAVSV
                     PKDDRRIKSVSLETGPKKTSYAEGEDLDLRGGVLRVQYEGGTEDELIRLTHAGVSVSG
                     FDTHHKGEQNLTLQYLGQPVNANLSVTVTGQDEASPKTILGIEVSQEPKKDYLVGDSL
                     DLSEGRFAVAYSNDTMEEHSFTDEGVEISGYDAQKTGRQTLTLRYQGHEVNFDVLVSP
                     KAALNDEYLKQKLAEVEAAKNKVVYNFASPEVKEAFLKAIEAAEQVLKDHETSTQDQV
                     NDRLNKLTEAHKALNGQEKFKEEKTELDRLTGEVQELLAAKPNHPSGSALAPLLEKNK
                     ALVEKVDLSPEELATAKQSLKDLVALLKEDKPAVFSDSKTGVEVHFSNKEKTVIKGLK
                     VERVQASAEEKKYFAGEDAHVFEIEGLDEKGQDVDLSYASIVKIPIEKDKKVKKVFFL
                     PEGKEAVELAFEQTDSHVIFTAPHFTHYAFVYESAEKPQPAKPAPQNTVLPKPTYQPA
                     SDQQKAPKLEVQEEKVAFHRQEHENAEMLVGEQRVIIQGRDGLLRHVFEVDENGQRRL
                     RSTEVIQEAIPEIVEIGTKVKTVPAVVATQEKPAQNTAVKSEEASKQLPNTGTADANE
                     ALIAGLASLGLASLALTLRRKREDKD"
     gene            11944..13575
                     /locus_tag="VVR63_000985"
     CDS             11944..13575
                     /locus_tag="VVR63_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HEU6129014.1"
                     /translation="MSINWQEILFHFLGGLGLFLYSIKTMGDGLQQAAGDRLRFYIDK
                     YTSNPFFGVLVGIGMTALIQSSSGVTVITVGLVSAGLLTLRQAIGIVMGANIGTTVTS
                     FLIGFKLGNYALPMLFIGAVCLFFTKNRTVNNIGRILFGVGGIFFALNLMSGAMAPLK
                     DLQVFKDYMIELSKNPVLGVFVGTGLTLLIQASSATIGILQNLYAGNLIDLQGALPVL
                     FGDNIGTTITAIIASLGANIAAKRVAGAHVAFNVIGTVVCVIFLVPFTVLIHWFEATL
                     NLAPEMTIAFAHGTFNITNTIVQFPFIGALAYFVTKIIPGEDEVVKYEPLYLDEHFIK
                     QAPSIALGNAKKELLHLGNYAAKAFDLSYKYIIDLDEKVAEKGHKTEEAINTIDEQLT
                     RYLIALSSEALSQKESEVLTNILDSSRDLERIGDHTEALLNLTDYLQRKNVEFSDAAL
                     KELEEVYRQTSDFIKDALDSVENNDIEKARSLVERHEAINKIERVLRKTHIKRLNKGE
                     CSTQAGVNFIDIISHYTRVSDHAMNLAEKVFAEQI"
     gene            complement(14134..15741)
                     /locus_tag="VVR63_000986"
     CDS             complement(14134..15741)
                     /locus_tag="VVR63_000986"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HEU6129015.1"
                     /translation="MSTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPY
                     INIDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRK
                     ERRGEYLGATVQVIPHITDALKEKIKRAALTTDSDVIITEVGGTVGDIESLPFLEALR
                     QMKADVGADNVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPA
                     GQGIKNKLAQFCDVAPEAVIESLDVEHLYQIPLNLQAQGMDQIVCDHLKLDAPAAAMT
                     EWSAMVDKVMNLKKQVKISLVGKYVELQDAYISVVEALKHSGYVNDTEVKINWVNAND
                     VTAENVAELLSDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGVCLGMQLTCIEF
                     ARHVLGLEGANSAELAPETKYPIIDIMRDQIDIEDMGGTLRLGLYPSKLKRGSKAAAA
                     YHNQEVVQRRHRHRYEFNNAFREQFEAAGFVFSGVSPDNRLVEIVEIPENKFFVACQY
                     HPELSSRPNRPEELYTAFVTAAVENSN"
     gene            complement(16131..16718)
                     /locus_tag="VVR63_000987"
     CDS             complement(16131..16718)
                     /locus_tag="VVR63_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HEU6129016.1"
                     /translation="MELEVFAGQEKSELSMIEVARAILELRGRDHEMHFSDLVNEIQN
                     YLGTSNSDIREALPLFYTELNFDGSFISLGDNKWGLRSWYGVDEIDEEIIALEENDDD
                     EVAPKAKKKRVNAFMDGDSDAIDYNADDPEDEDAYEADPALSYDDENPDDEKNEVEAY
                     DAEINEIAPDDLGEDVDLNEDDDEFSDDDAETSEE"
     gene            complement(16846..17295)
                     /locus_tag="VVR63_000988"
     CDS             complement(16846..17295)
                     /locus_tag="VVR63_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6129017.1"
                     /translation="MCFVPYYKVNHCEEAFAWYQDVNLVYLVDGVKLPYSQATLEAMY
                     SYLDRHGELFWIEVKEKGEWFPIGDITLSQDNLPIVIGNSAYQHRGLGKKILSALIEL
                     ARVKGWKELRVKEIYTYNHASRRCFKSLGFVENGATEKGRSFILELV"
     gene            complement(17300..17689)
                     /locus_tag="VVR63_000989"
     CDS             complement(17300..17689)
                     /locus_tag="VVR63_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partitioning protein ParB"
                     /protein_id="HEU6129018.1"
                     /translation="MKVNIADLHPTQLYLSEKKLQDIQMLYQSAETIQVDPISILAFG
                     DCLLITDGHHRAYQTLLADRDTISAEWDRDGGDELYHLYAQACEERKIYSVFDLEDRI
                     LAQDGYEAKWYNWCDGFNQAATLLLKR"
     gene            complement(17717..18343)
                     /locus_tag="VVR63_000990"
     CDS             complement(17717..18343)
                     /locus_tag="VVR63_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEU6129019.1"
                     /translation="MKGSFALLLFVILGYMVKFYPETLVNFDQSIQTAIRGDLPDYLT
                     ILFRALTRLIDIPVIITWVVITAFVFYRKRWKIESFFMLGNLALAGLLIVTFKNIYQR
                     PRPDILHLVEEKGFSFPSGHSLAVTLMVGTLIVILSQRIKDPVWRKIVQIVLGLYLVS
                     VLVSRVYLGVHYPSDVLASLCVGLGVLFIEFPFYDKLRFQWRFKGKQK"
     gene            complement(18357..18920)
                     /locus_tag="VVR63_000991"
     CDS             complement(18357..18920)
                     /locus_tag="VVR63_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEU6129020.1"
                     /translation="MTNTRRLSTIAILSAISFVLMYFDFPLLPAASFLKIEFSILPVL
                     VGLVVMDLPAALGVLLLRSLLKLLLNSQGVNTYIGLPMNIVALGVFVIVFALIWKKER
                     TTLRFLLGSLAGTIGLTLAMLVLNYVYAVPLYAKFANFDIGKILGLSNYLMTMVLPFN
                     LIEGVIFSVSFWLLYVLLKPTLKHYER"
     regulatory      complement(19085..19319)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(19373..19876)
                     /locus_tag="VVR63_000992"
     CDS             complement(19373..19876)
                     /locus_tag="VVR63_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HEU6129021.1"
                     /translation="MTNHIVLFEPQIPQNTGNIARTCAATNSPLHIIKPMGFPIDDRK
                     MKRAGLDYWDKLEIYFYESLEDFISQMKGKLYLISKFAEKIYSEVDLSTDEDHYFLFG
                     REDKGLPEDFMREHPEKALRIPMNDEHVRSLNVSNTVCMIVYEALRQQNFAGLELVHT
                     YEVDKLK"
     gene            complement(20069..20899)
                     /locus_tag="VVR63_000993"
     CDS             complement(20069..20899)
                     /locus_tag="VVR63_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEU6129022.1"
                     /translation="MQAKLIGYQHRDTVIHRLSGAGKLLFFILVSLAAMISYDTRMLL
                     LIAIFSVFLLYLSEIRFKDVSFVAVFATVFAVLNVLMVYLFSPEYGVGLYGERSVIWQ
                     GIGVYTLTSQELFYLLNLAIKYLCTIPLAIIFLMTTHPSQFASSLNQIGVPYKIAYSV
                     SLTLRYIPDLQEEFFTIKMSQEARGMELSKKASLMQRIKGNLLIITPLIFSSLERIDT
                     IATAMELRRFGKEKKRTWYSYQALKKGDYITLLLATLFLVVSLLLILQNQGRFYNPWK
                     "
     gene            complement(20884..22566)
                     /locus_tag="VVR63_000994"
     CDS             complement(20884..22566)
                     /locus_tag="VVR63_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6129023.1"
                     /translation="MKEAIIEWKDFSFRYETQQEPTLQGIDLTIYKGEKVLIVGPSGS
                     GKSTLGQCLNGIIPNIYKGQTYGEFLIKGQVAFDMSIYDKSHLVSTVLQDTDGQFIGL
                     SVAEDLAFALENDVTALDEMKGRVYKWAEKLDLLPLLDQRPQDLSGGQKQRVSLAGVL
                     IDESPILLFDEPLANLDPKSGQDIIELIDQIHKEEGTTTLIIEHRLEDVLHRPVDRIV
                     LISDGRILFNGSPDQLLATDLLTQNGIREPLYLTTLRQLGVDLVKEEQLANLDNMSIS
                     KGQVQLQNELAKETPELQSLFKLEDVSFSYDDRPILKSLHLDIKKGEKIAIVGKNGAG
                     KSTLAKAISSFIQTEGRYLWEKQDIKGDSVAERAERVGYVLQNPNQMISTNMIFDEVA
                     LGLRLRGVDEKEIETRVYETLKICGLYEFRNWPISALSFGQKKRVTIASILVLGAEII
                     LLDEPTAGQDQKNYTEIMEFLEELHQKGHTIVMITHDMQLMLDYSDRVLVMVDGELIA
                     DTVPASLLSDPELLVKANLKETSIFNLAKKLDVDPLDLTAFYKERREGCKLN"
     gene            complement(22668..22925)
                     /locus_tag="VVR63_000995"
     CDS             complement(22668..22925)
                     /locus_tag="VVR63_000995"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6129024.1"
                     /translation="MKIKEQTRKLAAGCSKQCFEIVDRTDEVSSKHGFEVVDETDEVS
                     NHTYGKAKLTWFEEIFEEYKMMGKAGQLVFFDVYRLVRQVS"
     gene            complement(22932..23480)
                     /locus_tag="VVR63_000996"
     CDS             complement(22932..23480)
                     /locus_tag="VVR63_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF-type riboflavin transporter
                     substrate-binding protein"
                     /protein_id="HEU6129025.1"
                     /translation="MEIKFTIKQVVAVGIGAALFVVIGMINIPTPVPNTSIQLQYAVQ
                     ALLSIIFGPIIGLLVGLIGHAIKDSLAGYGLWWTWIIASGLFGLVVGLFRKYVRVING
                     VFDWKDILIFNLIQLLANALVWGVLAPLGDVVIYQEAAEKVFAQGIVAGIANGVSVAI
                     AGTLLLLAYAGTQTRAGSLKKD"
     gene            complement(23495..24343)
                     /locus_tag="VVR63_000997"
     CDS             complement(23495..24343)
                     /locus_tag="VVR63_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosyl-l-methionine hydroxide
                     adenosyltransferase family protein"
                     /protein_id="HEU6129026.1"
                     /translation="MNNNLLVLQSDFGLVDGAVSAMIGVALEESPTLKIHHLTHDITP
                     YNIFEGSYRLFQTVDYWPEGTTFVSVVDPGVGSKRKSVVAKTAKNQYIVTPDNGTLSF
                     IKKHVGIVAIREISEVANRRQNTEHSYTFHGRDVYAYTGAKLASGHITFEEVGPELSV
                     EQIVELPVVATIIEDHLVKGAIDILDVRFGSLWTSITREEFYKLEPEFGDRFEVTIYH
                     ADMLVYQNQVVYGKSFADVRIGQPILYINSLYRLGLAINQGSFAKAYNVGVGSSWTIE
                     IKKIEG"
     gene            24531..25880
                     /gene="trkA"
                     /locus_tag="VVR63_000998"
     CDS             24531..25880
                     /gene="trkA"
                     /locus_tag="VVR63_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HEU6129027.1"
                     /translation="MKIILVGGGKVGFALCRSLVAEKHDVLLIEQDEAVLNHIVSRFD
                     IIGILGNGADFAILEQASVQDCDIFIALTEHDEVNMIAAVLAKKMGAKETIVRVRNPE
                     YSNSYFKEKNILGFSLIVNPELLAARAIANIIDFPNALSVERFAGGRVSLMEFVVKST
                     SGLCQMPISDFRKKFGNVIVCAIERDHQIIIPSGDMTVQDKDRIFVTGNRVDMILFHN
                     YFKSRAVKSLLIVGAGRIAYYLLGILKDSRIDTKVIEINPEIASFFSEKFPNLYIVQG
                     DGTAKDILLEESAQHYDAVATLTGVDEENLITSMFLDRVGVQKNITKVNRTSLLEIIN
                     APDFSSIITPKSIAVDTIMHFIRGRVNAQYSDLQAMHHLANGQIETLQFHIKEANKMT
                     AKPLSQLKLKKGVLIAAIIRKGKTIFPTGEDMLEVGDKLLVTTLLPNITKIYDLIAR"
     gene            25884..27323
                     /locus_tag="VVR63_000999"
     CDS             25884..27323
                     /locus_tag="VVR63_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEU6129028.1"
                     /translation="MNKSMIRYLLSKLLLIEAVLLLVPVAIAVYYRESSQVFTALFST
                     IGILVLLGGSGSLQKPKNQRIYAKEGVLIVALCWILWSFFGGLPFVFSGQIPSLIDAF
                     FEISSGFTTTGASILNDISVLSRSLLFWRSFTHLIGGMGVLVFALAIMDNAKNSHLEV
                     MKAEVPGPVFGKVVSKLKNTAQILYLLYIALFSLFVIIYYLAGMPLYDSFVIAMGTAG
                     TGGFTVYNDGIAHYGSSLITYLVSIGVLVFGVNFNLYYYLMLRRVKAFFGDEELRAYL
                     VIVLVSTGLISLNTLYLYPGFSKSFEMTFFQVSNIITTTGFGYGDITNWPLFSQFILL
                     FLMAIGGSAGSTAGGLKIIRGLILSKIAKNQILSILSPHRVLTLHVNKMVIDKDTQHK
                     ILKYFVIYAMILLALIFIVSLDSNDFLVVTSAVFSCFNNIGPILGTTSSFSIFSPISK
                     ILLSFAMIAGRLEIYPILLLFMKRTWSKR"
     gene            complement(27448..27705)
                     /locus_tag="VVR63_001000"
     CDS             complement(27448..27705)
                     /locus_tag="VVR63_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HEU6129029.1"
                     /translation="MNEGAQLAEVRVIANSGAYGAHYDIMGVYDLIILAPQVRSYYRE
                     MKVDAERLGIQIVATRGMEYIHLTKNPSKALQFVLEHYQAV"
     gene            28465..28635
                     /locus_tag="VVR63_001001"
     CDS             28465..28635
                     /locus_tag="VVR63_001001"
                     /inference="COORDINATES: protein motif:HMM:NF024172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU6129030.1"
                     /translation="MTKQVPKFTKDTAQLYTCKWLLYNKVTKMYDHTVVNHSVREYIT
                     DSISTNTIEETG"
     gene            29247..29531
                     /locus_tag="VVR63_001002"
     CDS             29247..29531
                     /locus_tag="VVR63_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6129031.1"
                     /translation="MDWYDYMIQASKQSQFNASHWFRYLRKVIFEDYSYLTNQDVEKL
                     LDSKELTRFQKISLKYAFQEHTPTHKYVISLNKPAKLTNVQKLMEKYKHG"
     gene            29524..29762
                     /locus_tag="VVR63_001003"
                     /pseudo
     CDS             29524..29762
                     /locus_tag="VVR63_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397100.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            29858..30076
                     /locus_tag="VVR63_001004"
     CDS             29858..30076
                     /locus_tag="VVR63_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6129032.1"
                     /translation="MMSIREQDLKDIGAIIKYKNFHSPFDTFKYLKDMGFDTIDLSVL
                     LEGFSYAYGMDWLEKFFKENQDKLREFY"
     gene            complement(30443..32767)
                     /gene="pflB"
                     /locus_tag="VVR63_001005"
     CDS             complement(30443..32767)
                     /gene="pflB"
                     /locus_tag="VVR63_001005"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HEU6129033.1"
                     /translation="MVVKTVVEAQDIFDKAWEGFKGVDWKEKASVSRFVQANYTPYDG
                     DESFLAGPTERSLHIKKIVEETKAHYEETRFPMDTRPTSIADIPAGFIDKENEVIFGI
                     QNDELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKYVTTVNDGIFRAYTSNIR
                     RARHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAIKEIDEETIRLRE
                     EVNLQYQALQQVVRLGDLYGVDVRKPAMNVKEAIQWVNIAFMAVCRVINGAATSLGRV
                     PIVLDIFAERDLARGTFTESEIQEFVDDFVMKLRTVKFARTKAYDQLYSGDPTFITTS
                     MAGMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYNFRRYCMHMSHKHS
                     SIQYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNG
                     GYDDVHKDYKVFDIEPIRDEVLEFESVKANFEKSLDWLTDTYVDALNIIHYMTDRYNY
                     EAVQMAFLPTKQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYP
                     RWGEDDPRSNELAEWLIEAYTTRLRSHKLYKDAEATVSLLTITSNVAYSKQTGNSPVH
                     KGVYLNEDGSVNLSKLEFFSPGANPSNKAKGGWLQNLNSLSSLDFSYAADGISLTTQV
                     SPRALGKTRDEQVDNLVTILDGYFENGGQHVNLNVMDLNDVYKKIMSGEDVIVRISGY
                     CVNTKYLTPEQKTELTQRVFHEVLSMDDALDALS"
BASE COUNT         9752 a         7044 c         5948 g        10261 t
ORIGIN      
        1 tcacaaaaat agcaggtagt cagtttgacc acctgttatt ttttaccaat taacaatttt
       61 atctacaata ttttgttgtt cagtagctgt tttccttaga taaattcgag tagtttctat
      121 actttcgtgt cccatcaaat ctgcaagcaa ggcaatatca ttatacttcg ctaaaaaatt
      181 cttagcaaat aaatgcctaa aagaatgagg gtaaattact ttaggattca ttttgtattt
      241 atcagcataa ttttttaact gttgagcaac tcctcttgct gtaattggtt cgttaaattt
      301 attcaaaaat aaataaccac ttcggcgatt ttctgattct aaccaactaa gacaactatt
      361 tcttaatttt ttaggaatgt acagtctacg aattttacca ccttttgagt aaatgtcaaa
      421 ataaccgatt tctacatgct ctacttttag tttaataagt tcacttacac gagccccagt
      481 tgcacctaaa aaccaaacga caaaatgcca ttttaaaata ccatcttttt tcaaactacg
      541 tttaagaaaa aggtaatcag catggctaat gacatcttct aaaaatggtt tttgctgtac
      601 tttgacaaat tttaatttca aatcatcatg accaataaaa gccagatatt tatttactcc
      661 ttgtagtcgc aaattgacag ttttaggttt aaaattgtct aataaatatc ctttgtattc
      721 aaataaatct tccattttga gttcgtaatt ctccaagaaa aatcgaacac cataaaggta
      781 cgaacgcaca gtattttcag ctaaaccagc tttcttcaaa tgtaattcaa aatctttcaa
      841 cgtaaaactc ctatcttatg tttgatagaa attccaccgc acgtaaaact attatactaa
      901 attagtgcgt caatatgggc gaaaaattgt tcgattttat caacgattct ggattgttca
      961 ggaaggggtg ggagggggat taaatattct tttatagttt tcgttaataa ttctttttgt
     1021 tttgtactac ccgacgcttt ttcttcaata actgactgaa caataggaga ggaaagaaaa
     1081 ttatagatga aatggcaatt aataactccc gataagactc ttataactgt aacatggcta
     1141 tctgcaacag cccagccata aggattttta ttttcatggt aaatagctaa tcgtcctaac
     1201 gtacctagac ctgttgaatt ccacattaaa tcaccatctc ttagtaatct ttctttctgg
     1261 taactatgaa ctgtttcggg atcaataaat cttgctaagt caatagaaaa gccagaccat
     1321 tgattacatt tctgagcaat cacagggtat ataggaatat ttgaatattt tggagacttc
     1381 cctctttgaa tgtaggaggt tatatcgttt aacctcaccc attcccaact ttctggtatt
     1441 tcacaaggta cttcctcata ataagagtta tcatctcctt gggaaacaat agaaatgtcc
     1501 aaatctttct ttttaatctt gccttcttca aagagttttt gtttttctgc tcgtattttt
     1561 tcaagtaaaa cttcgactga ttcatcattt gggtcttgtt caactaattt tccttgcata
     1621 gcatattgaa gaatagattt ttttagttta tctggaaatt ctttatctag ctgttctagt
     1681 ctattataac tttcagcata ttcatctact ttttctaaag ctgattcgat tgcttctatt
     1741 atgcgttgtt gttcggatag tggggggaga gggataagaa tagaagcaac tttatcacta
     1801 ttcaagtttt tcacaacagc tccactaatt agagatagaa attgagaata aactacattt
     1861 gatgaaagaa tatagaatag gtaatcttta tttaatgagt tttcatagtt cgaaatagcc
     1921 aaccatccat cgtgtattgc accatcaaca ttcaaaatat aaggtctacc aaaactcata
     1981 gaattagtta acaaaaatgt accttttttt acaaatctag ttttgttaag ccctgatttt
     2041 ttgatttttt ctttaacatt atttatatac ttttcaccct tttcagtatc acctattttt
     2101 atccaattta ttccatctac ttcagaagta agataatctt tgattggtcg tggagagcca
     2161 cctctgacaa tttcaaccaa tgtagaaaac ctcacccact cccaagtatc aggaatatca
     2221 taaggaacat caatttcttg agtgcttcca tcagcaaact tcccataatg tttcttatgt
     2281 gcttcaagta tataaaaagg cgtaaaaata cgcctataga taatggggtt gaaataggtt
     2341 tattgttgat gagattgtag ataattcaat tttttacttc caatcgaata ttcaaaacct
     2401 ccaccttttc tgcctgtaat tgttcatcat aaaattcaat atcttcagga ttttcccctt
     2461 ggcaacctcg gcagaaatat tcttccgctc gatcaggatt caaaaatcga caagcacaaa
     2521 caaaacagtc gccatcatca tttattgaga taatatagta gattgaaata agatgtaaac
     2581 aaatcgatta ggaaagttaa attagtttct agaaattttt agcagatgta gtgtactatt
     2641 ctagtctcaa tttactatgg cttcaaatat atctttcgaa aaaatattta cagatgtgta
     2701 attttgaagc ttgcaaaagt tagtaaactt gtagatttcg atttgaagta acttgttttc
     2761 ttgcccgata ttgtttttga aattgaattt ttccatagtg actccttaat tttcttctac
     2821 acgtctgatg ataaatctaa ttcgcaaaag agtcaagagg atttttcgaa aaataaatag
     2881 cgaccgaaat cgctatttta agggttatag gtatttgatg gcttagactg ctgtgtgact
     2941 gtttacccac aggcaatctt tcttctatat tagtattagt aaaggtctaa ataattatca
     3001 atttcccatt gtgaaacgaa ggttgcataa cttgcccatt cgattcgttt ggcttcaagg
     3061 aagctagtat agatgtgatc tccgagagca gctttaacca cttcatcttc tgtcaaagct
     3121 ttcaaagcgt tgtgaagagt tgatggaagg tctgtaatac cagcttcctt gcgctcttct
     3181 gctgtcatga tgtagatatt ttcttcgata ggagctggtg cttcgatttt attttcaata
     3241 ccatacaaac caacttccaa aagaacagcc atagcaacgt aagggttcgc cattggatcc
     3301 actgaacgca actcaagacg agttcccata ccacgtgaag caggtacgcg cacaagtggc
     3361 gaacggttac gaccagccca agcaatgtaa acaggcgctt cataacctgg aaccaaacgt
     3421 ttgtatgagt taactgttgg gttcatgatg gcagtatagt tgtaagcatg cttgatcaaa
     3481 ccgcctagga aatggtaagc tgtttctgac aactgcattc cttttggatc atttggatca
     3541 aagaaggcgt tatttccttc tgcatcaaac aaggacatat tacagtgcat acctgagcca
     3601 gcaataccaa attttggctt cgccataaat gttgcgtaaa gtccgtgttt gcgagcaatg
     3661 gttttaacaa caagtttaaa gatttgaatc ttatcacaag cacggagaac ttcatcgtac
     3721 ttaaagtcaa tctcatgctg tccaaccgca acctcgtggt gactcgcttc tacttcaaat
     3781 cccattttgg tcaagacatt cacaatctca cgacgtgtgt tgtccgcaag gtcagtaggt
     3841 gccaaatcaa agtagccacc cttgtcattc acttcaagtg ttgggtcccc attttcatcc
     3901 aacttaaata ggaagaattc tggctctgga ccaaggttga aggatttgaa tccaacttct
     3961 tccatgtgac gaagagctcg tttcaaatta ccacgagggt cacccgcaaa tggttcacct
     4021 tctgttgtat aaacatcaca gatcagacct gcaacacttc cattttcatc tccccaaggg
     4081 aagactgtcc atgtatccaa gtccgggtac aagtacatat ccgactcatt gatacgtaca
     4141 aaaccttcaa tagaagatcc atcaaacata accttgttcg acaagacctt atctaactgt
     4201 tcatctgtag caggaatttc gacgtttttc atggttccca aaatatctga gaacataaga
     4261 cgaataaagg taacattttt ttccttgact tcacgacgaa tatctgcagc tgtgattggc
     4321 ataagttttc tccttaatct atgactactt gcggttgcct aaccgcgacc aaaaggtgac
     4381 tgtactgaag caaaacgccc ctgttggagg agttcattgt gaagtgcacg acgtacttca
     4441 gtctgactaa ccgctttctt ggatttcgct tcacgttcag catatttttt cttaatggca
     4501 gcgatattat aaccttcaga gatataatct ttgatttcaa gcagacgatc catgtcattc
     4561 aaggaataca tgcgacgatt tccttcgttt cgatcgggct tgatcaactc ttgattttca
     4621 taataacgaa tctgacgcgc cgatagatcg gtcaacttca taacactgcc gataggaaaa
     4681 acagccatat ttcggcgaaa ttctttttcc ttcatttaca atttccttct ttctgtctat
     4741 tatagtctaa aaaaagacaa acgtcaatta ataatgttat aaaatgtaac attatttttc
     4801 ttttttctct aaaaagagac gaatacgatc aatatcgtaa tttacgataa ttgcgacaaa
     4861 aactcccata aatgtttcta atacacgcac aaacacgtac aaaattgtct caccacttgg
     4921 aattgatagg gtaataatta acatagctgc tacaccacca ataacccctg ctttgttatt
     4981 catggctaca tttgtcataa tggttaacat ggtgcagatt ggaacaacta ccaaggtcac
     5041 ccaaaaggct tcgtggaaaa aggtatttaa taagaagaag accaaggcat agagtccacc
     5101 gatactattt cctagaatac gcgaagtccc aaaatgaaca ctctcatcaa aactctccct
     5161 caggctaaaa acggctgtca aagcaccaat ttgaagacct ttccagccaa aaaagccaaa
     5221 aatcaagaga actagaaaaa cagcaatacc tgttttaaag gttcgcatac caagtttgaa
     5281 ctgggattta tcgaatttat attttttaaa ataactcata atctcaactt tctatttcca
     5341 ttttatcata aatcggtgat ttttatgagt aatagttgag aggaagcgtt tttattttaa
     5401 gcaaaagaaa agaggaactt tcatccctct cttctttgat ttgtttataa aatcttattt
     5461 ttctgtcaag gctgcaagtc ctggaagaac cttaccttca agaagttcca ttgatgctcc
     5521 accacccgta ctaatccatg agaacttgtc tgcacggcca aggttaatcg ctgcggcagc
     5581 tgagtcacca ccaccgatga ttgatttaac tcctggttgt ttcacgatag cgtccatcac
     5641 accgattgta ccagcttgga aatctgggtt ttcaaataca cccataggtc cgttccatac
     5701 aactgttttg gcaccagtca aagcttcgtc aaatttggcg atagattttg gaccgatgtc
     5761 aagaccaagg aagccttcag aaactgcttc accttcagtg tcacgcactt cagtgtaacc
     5821 agcaaatgcg ttagcttctt ttgagtcaac tggcaagatc aatttaccat ttgctttttc
     5881 aagaagagct ttcgcaacat ccaatttgtc ttcttctaca agtgagttac cgatttcgat
     5941 accttgtgct ttgtagaatg tgtaagtcat cccaccaccg ataaggactt tatcagcttt
     6001 ttcaagcaag ttttcgataa caccgatctt gtctgaaact tttgaaccac caaggatagc
     6061 cacgaatgga cgttctggag tttcaactgc ttcttggatg taggcaattt cgttttcaag
     6121 aaggaaacca gcaactgctt tttcaacgtt tgctgagata ccaacgttag atgcgtgtgc
     6181 acggtgagct gtaccgaatg catcgtttac gaagatacca tctccaagtg atgcccagta
     6241 tttaccaagt tcaggatcgt ttttagattc tttcttgccg tcaacatctt cgtaacgagt
     6301 gttttcaacc aagagaactt gtccatcttc aagagcgttg attgccgctt ccaattcagc
     6361 accacgagtg acacctggga aaacaacatc ttgaccaagt tttgctgcca agtcagctgc
     6421 tacaggagca agtgatttac cagctttatc agcttcttct ttcacacgtc caaggtgaga
     6481 gaaaagaatt gcacgtccac cttgttcgat gatgtactta atagttggaa gagctgctgt
     6541 gatacggtta tcgttagtga ttacgccatc tttcaatggt acgttgaagt caacacgaac
     6601 gaggactttt ttacctttca agtcaacgtc tttaacagta agttttgcca tgttacaaaa
     6661 actcctttat ttattttatt cgaaactatt atatcacact ttagaaatat aaggaaagat
     6721 ttcacaagat ttttcgatat ttaatcttta tcttctcttt tccgtctcaa ggtcaaggct
     6781 aaactagcaa gaccaaggct ggctaagcct gctattaggg cttcattagc atcagctgtt
     6841 cctgtatttg gcaattgttt gcttgcttct tctgatttaa ctgctgtatt ttgagctggt
     6901 ttttcctgtg tagctactac tgctggtact gtttttactt ttgttccaat ttcaacaatt
     6961 tctggaatcg cttcttggat gacttctgtt gaacgaagac gacgctgacc gttttcatca
     7021 acttcaaaga catgtcttaa cagtccatct cgtccctgta tgatgactcg ttgttcccca
     7081 actagcatct cagcattttc atgctcttga cgatgaaagg caaccttttc ctcttgaact
     7141 tccaatttag gagccttttg ttgatcagaa gccggttgat aagtaggttt tggaaggact
     7201 gtgttttgtg gtgctggttt agcaggttgt ggtttttcag cagattcata aacaaaggca
     7261 taatgagtaa agtgaggtgc tgtaaagata acatgactat ccgtttgttc aaaagccaat
     7321 tctactgcct ctttgccttc aggtaagaaa aatactttct taactttctt atctttttca
     7381 attgggattt tcacaataga agcataagag agatcaacat cttgaccttt ttcatccaaa
     7441 ccttctattt caaagacatg agcatcttct ccagcaaagt atttcttctc ttcagcactt
     7501 gcttgaacac gctctacttt caaacccttg atgacagtct tctctttatt tgagaagtgt
     7561 acttcaacac ctgttttact atcagaaaag actgctggct tgtcttcttt caataaagca
     7621 accagatctt ttagactctg tttcgctgtt gcaagctctt ctggactcaa atctactttt
     7681 tcaaccaagg ccttgttttt ctcaagaagc ggagctaggg cagaacctga aggatggttt
     7741 ggtttggcag ccaagagttc ttgaacctca cctgttaaac gatcaagctc tgtcttttct
     7801 tccttaaatt tctcttgacc attcagagct ttatgagctt ctgtcaattt attaagtcgg
     7861 tcattgactt gatcttgggt gctagtttca tggtctttca acacttgttc ggccgcttca
     7921 attgctttca agaaagcttc ttttacttct ggtgaagcaa agttatagac caccttgttc
     7981 ttagcagctt caacttctgc taatttttgt ttgaggtact catcgttcaa tgctgctttt
     8041 ggagatacca aaacatcaaa gttgacttca tgaccttggt aacgaagcgt caaggtttga
     8101 cgaccagtct tttgagcatc gtaaccagaa atttcaactc cctcatcagt aaaggaatgt
     8161 tcttccatgg tgtcattgct ataagccact gcaaagcgtc cttcagacaa gtctaagcta
     8221 tcaccaacta ggtaatcttt tttcggttcc tgacttactt caattcccaa aatagttttc
     8281 ggacttgctt cgtcttggcc agtgacagtc actgacaaat tagcatttac tggttgtccc
     8341 aaatattgga gagtaagatt ctgttctccc ttatgatgcg tatcaaaacc tgatactgat
     8401 acacctgcgt gagttaggcg aatgagttcg tcctcagttc ctccttcata ctgaactcga
     8461 agaacaccac ctctaaggtc caaatcctcc ccttcggcgt agcttgtttt cttaggtcct
     8521 gtttctaggc tgactgactt gattcttctg tcatcttttg gaacggaaac tgctaggaca
     8581 ttactaattt ccttgcctgg caactgggta cgataataaa gaagaccaga ttgatttgtc
     8641 aaatccaatg gtgcacttgc taggtctcct ccaacttcgc tcttcaaggt tgcgagtgga
     8701 gtttgagaat ttggattatc ataaacggta atagttgctc cagccggtac atctgcaaag
     8761 ccaacttgta ccttgttatt gcctagagaa cgggctgcag ccttggccat cggaatattg
     8821 acactctcag tatcaagctt ttcatacatt ttccagttat agatacgaat agccttccat
     8881 ggagttccat tgtcagaagt gacaacattc aagcgccagt cttgagcagt gattggttta
     8941 tcaagagtga tatctgtcac gtgtgctttg ttgccacgga cttccttagc tagcttccac
     9001 tcaccatctg catctttata ataaaggtca aagtctttgg tgttcatcaa gccatcgtta
     9061 acagactcac caccagcccc tgcatgatcc atgacccatc taacaacggt acgtggcttg
     9121 gtcaaacgaa tatccacact accactcaac tgagctgaag accatttatc tgacaagcta
     9181 gtaatggtac cgttcaacat accttcaata ccttctccac cttctgtatc tgggaaggta
     9241 cttccgataa cagtagcccc tggaacgatg ttttctgcta gaggtcttgg aagacttgtg
     9301 tcttggacag tcatccccca ctcaaaggtt gtggttgcag cttctgaacg aactccattt
     9361 ttaccgactg ctacaacctt cagttcttga gttgtaccct gagcacttgc tgagcggcta
     9421 acttttggta gataaatagt tgtagaagat gagccagtta gtaatttcca gctgtctcca
     9481 tctttttcat aaacttcata gaaatctgca tccttgttgc ctttaaattg cacaactgct
     9541 tccgcttctt gggcattttt aagagattgt ttcactacag aaaagcttgt cggcgattgt
     9601 ggctcttggt gattgtccga gatagttaat tgtcctaggt tgaactgata atcttttaca
     9661 gcaccttcat gctcgaaaaa tagtttgact gcatagatgg ttttacctgc tagtgagctg
     9721 agatcaaatt cttcatttgt ccagttgtca gaaagggtta gctctttcca tgcatctgca
     9781 tcatcgaatt tgtagtctgg agttgtagag aatgccatat aaactttaga accttttcct
     9841 cccttgtggg caacacgaag tttggtcttc tcagttactt ctaacttagt agaataaagt
     9901 ctcacatcct gatctgtctt accggctaca tcaccagaga atttaaggga atttccgcca
     9961 ttataggcat ctgtaaaatc atattctgca cgaagttttt cccctgttga agtctgccac
    10021 cagcgccatg ttggaagaac acctgatact gaacgataat tccactcaga atccttagaa
    10081 accttaccat ctacgaacca ttttttacca tgacctgtat taaaagaagt agtaaaagta
    10141 ttacctaccg ctggcgtacg gtccgcaact aggttagcaa taccatacca atctttgtca
    10201 cctggttttt gaccagtagg gtctccttga taacctgtaa agaagatatc ttcattttta
    10261 tgataatctt caccagtttt tcctaaactt gtaatggtat ctggggcaaa taaaccaaga
    10321 gaaaggcgca atttcccatt ttcgtctaaa atgtcattcc acttaacctt tgtcttgtag
    10381 gaaccaccct gttgcaattc caaacctgca aatacatcat aaggattacg accaatccag
    10441 ttggcagttg caatagtgta atcattttta gccttatccc agttaaagtt agcaaagaag
    10501 ttatctgccg gaaccttatc tccttctggt tgcatgaatt ggtagttgta ttctcccaaa
    10561 ccatcttgat ggtaacgtcc atagttatag gtcatggcat cataccaaga atacttgatt
    10621 ggatggttta ccttagcagc atattccttg ctatagagca taaactggcg catcttttct
    10681 ccaagaggtt taaccaaatc tccagttgtt tcttggttga tgaaatagcc atcatagcca
    10741 taatacttgg ccatgtctac caatttacgg gcaattggga agctaccatc tgcgtcttgc
    10801 ttcaaagctt cagcaaatct ttcttgatct gcaatactat tagaccagtt gaagaagagt
    10861 gtaccgtata caggaacccc gttacggtga cctgcatcaa taacgtcagg agttggtacg
    10921 agaccttccc agaagaccat tgaatctaga tattgccaat agtcaaaagc ataggccttg
    10981 aactcttctc caccaacaga agcatggtct tttgctttag aattggtgtt tgataaggct
    11041 tgaacttttg cttccttgct agctttttca ttgactaaat gacctgtccg acgtgaagcg
    11101 aggacaacag atccgcggtt aatagcatca tcttcacgag cacctggttc ccattttaac
    11161 aattcttccc aagaattaaa tttgatttcc tttggtttta atgttttttc tgtattttta
    11221 gggacatctg gctggacttc tttttcagtc ttattagctt ctgctgctgg cttagactca
    11281 tccccttggt tagttgcttc gggctttgct tctgtttcct tgtcagactt aggttttgct
    11341 tctgcagatg gtgtttctgc aaccacctca cctgcttttt cctctggttt agctgcgcta
    11401 gctgcttctg ccttttctag cttgttttct ctagcatgtt ccccttcatt ctgcttatca
    11461 gcttcattgg tcgaatgctc actctctcct gaaacaagct ctgtattagc tccgctattt
    11521 tcaggaactg cagtttcttc agccaaggct ggaccagcaa ataaaacagc accaatcatc
    11581 agcgagcagg ctcctactga taacttacga atactgtaac gacaacgtct ttcaaaaaat
    11641 ggattcttca ttttctcctc ctaaaagatt gattttgttg ttttaaagaa agcgctttat
    11701 attctgtagt tttttatcaa actctagaac catgataatc acatttttat cctaaaacat
    11761 ttttagacaa aaaacaataa ctgtttgcac aaatctaaaa taaggttaaa aactcttaaa
    11821 aataatacac ttatcaatta taattttctt ttacaaactt gacattaaca cttgttagat
    11881 ttacttttat cctttaaaat agaataggag atattccgcg attatttttc ggaggaaaaa
    11941 gaaatgtcca ttaattggca ggaaatttta tttcactttt taggtggtct ggggctattc
    12001 ttatatagca tcaagaccat gggagacggt ttgcaacaag ctgctggaga tcgccttcgt
    12061 ttttacattg acaaatatac tagtaatcct ttctttggag ttctggttgg tattgggatg
    12121 actgctctaa ttcagtctag ttctggtgta acagttatta cagtcggcct ggtcagtgcc
    12181 ggtctcttaa ccttacgtca ggctatcggg attgtcatgg gtgctaatat tgggacaact
    12241 gtcacatcct ttctcatcgg ttttaaatta ggtaactatg ccctacctat gctctttatc
    12301 ggtgccgtct gtctcttttt tacgaaaaat cggacagtca ataatatcgg acgcatcctc
    12361 tttggtgtcg gtggtatctt ttttgccctc aatctcatga gcggcgcaat ggctccactc
    12421 aaggatttac aggtctttaa ggactatatg attgagctaa gtaagaatcc tgttttgggt
    12481 gtctttgtcg gtaccggctt gaccttgcta attcaagctt cttcggctac cattgggatt
    12541 ttacaaaacc tctacgccgg caatctaatt gacctacagg gagctttgcc agttctattt
    12601 ggtgacaata tcgggacaac cattacagcc atcattgcct ctttaggggc taatattgca
    12661 gctaaacggg tagcaggagc tcatgttgcc ttcaacgtta tcggaacagt cgtctgcgtt
    12721 atttttctag ttccttttac tgtcctgatt cattggtttg aagctacgct aaatctagca
    12781 ccggaaatga ccatcgcctt tgctcacgga acctttaata ttaccaacac cattgtccaa
    12841 tttccattta tcggagctct ggcttacttt gtaaccaaga ttattcctgg agaggacgag
    12901 gttgtcaaat acgaaccctt atatcttgat gaacatttca tcaaacaagc cccatctatc
    12961 gctctaggaa atgctaaaaa agagctcttg cacttaggaa actacgctgc taaagccttt
    13021 gacctttcct ataagtacat cattgacttg gatgaaaaag ttgctgaaaa agggcataaa
    13081 accgaagaag caattaacac catcgatgag caattaacac gttatctcat tgccctttca
    13141 agcgaagctc tcagccaaaa agaaagtgaa gtgctcacca atatccttga ttcctcccgt
    13201 gatttggaac ggattggaga ccacacggag gctctactca atctgactga ctatcttcaa
    13261 cggaaaaatg ttgaattttc tgatgccgcc ttgaaagaat tagaggaagt ttaccgccaa
    13321 actagtgact ttatcaaaga tgctctggat agtgtggaaa acaatgatat tgaaaaagca
    13381 cgcagtcttg tagaacgtca tgaagcaatc aataagatag aacgtgttct cagaaaaacc
    13441 cacatcaaac gcctcaacaa aggcgaatgt tcaacacaag ctggggtcaa ctttatcgac
    13501 atcatctcac actacactcg tgtatcagac cacgctatga accttgctga aaaggttttt
    13561 gcagaacaaa tctaataacc aagaagctat ccatcataat tggatggctt cttacttttt
    13621 cctaagcaag actaggctga atgaaactga aagagtattc tgcagatata tagtatattg
    13681 aaactagaat agtacacctc tatttctaaa acattgttag aaatcgattt gactgtcctg
    13741 atcgatttgt cctgttatta tttcatttta ctatagtgga ttaaattaaa aaagtataat
    13801 gtattgaatc tataacagta catcttgact gctaaaatat ttctataaat taatttgact
    13861 ttccttatag agatgttcac atcttatttc aattcatgat acaatccagt tcctaaaact
    13921 ttgctagaaa ttaatttggc tttccgaatt aatttgttca gattttattt catttcaata
    13981 tactgataaa tccattcact agcacagggc aagagggagt cgctattgat ttcaacggta
    14041 gcaggtacat acagaggact cctacctcag atatactgca atatcatcgt atgcaaaaaa
    14101 cctctgagat ttttctcaaa ggttctgatt ttgctaattg ctgttctcaa ccgctgcagt
    14161 aacaaaggca gtgtagagtt cttctggtcg gtttggacgg cttgacagtt cagggtgata
    14221 ctgacaagct acaaagaatt tattttcagg aatttccacg atttctacca aacgattgtc
    14281 tggagaaact cctgaaaaga caaaacctgc tgcctcaaac tgctcacgga aggcattatt
    14341 aaactcataa cggtgacggt gacggcgttg caccacttct tgattgtgat aagcagcagc
    14401 agccttagag ccacgtttca acttagacgg ataaagtccc aaacgaaggg ttccacccat
    14461 atcctcaata tcaatctgat cacgcatgat atcaatgata gggtattttg tttctggtgc
    14521 aagctctgca gaattggcac cttcaagacc taaaacgtga cgagcaaact cgatacatgt
    14581 caactgcatt cccaagcaga ctcccaacat tggaacatca ttttcacgcg catagcggat
    14641 ggcttggatt ttcccttctg taccacgttg accaaaacca cctggtacga tgatcccgtc
    14701 cgcatcagac aagagttctg ctacattctc tgctgtcaca tcattggcat tgacccaatt
    14761 gattttaact tctgtatcat tgacatagcc agagtgtttc aaggcttcga ccactgagat
    14821 ataggcatct tgcaactcca catacttacc aacaagggaa atcttaactt gtttcttgag
    14881 gttcatgacc ttgtccacca tggctgacca ttctgtcata gccgctgctg gtgcgtctaa
    14941 tttcaaatga tcacaaacaa tttggtccat cccttgtgcc tgcaagttca gtggaatttg
    15001 gtaaaggtgt tcaacatcca acgattcgat aacggcttct ggtgccacat cacagaactg
    15061 ggccagttta tttttaattc cttgaccagc tggctcttct gtacgaataa ccaacatatt
    15121 tggttggatt cccaagccac gcaattcttt gacagagtgt tgggttggtt tggttttcat
    15181 ttcaccagca gccttgaggt aaggaagcaa ggttgtatgg atatacatga cattatccgc
    15241 acccacatct gccttcatct gacgaagagc ctctaggaat ggcaaggact cgatatctcc
    15301 tactgttcca ccaacctctg tgataatgac atcagagtcg gtcgttagag cggcacgctt
    15361 gattttttct ttcaaagcat ctgtgatatg aggaatgact tgaacagttg ccccaaggta
    15421 ttctccacgg cgttctttac gaagaacttc actgtaaatt ttcccagttg tcacgttgga
    15481 atatttgttg agattgatat cgataaaacg ttcatagtga cccaagtcca aatctgtctc
    15541 agctccgtca tctgtcacaa aaacttcccc gtgctggtaa ggactcatgg ttcccggatc
    15601 aatattgata taagggtcaa acttttgaat ggttactttg agaccacgat ttttcaagag
    15661 acggcctaga ctcgctgcca caatcccttt cccaatagac gataccacac caccagttac
    15721 aaaaatatat ttcgtagaca tagattcctc tttctaaaat gctcaaggtc ttgttaacta
    15781 cgaggggata tagaaaacaa gaccctacta ataagaataa tctgggacga ctgcaccaga
    15841 ttcacaacta atactcttcg aaaatctctt caaaccgcgt caacgtcgcc ttgccgtaga
    15901 tatgtgttcc tgactttgtc agtcttatct acaacctcaa aacagtgttt tgagcagcct
    15961 acggctagtt tcctagcttg ctctttgatt ttcattgagt ataaaataca agaagataac
    16021 ttcttgaaaa aacaaaaata gctccctaag aactagggag ccccgacctc taaaagaggt
    16081 gcccaaacaa tatgatacct aaaaatagga taattgtcaa tagctaactc ttattcctcg
    16141 ctggtttcag cgtcgtcatc tgaaaactcg tcgtcgtctt cgttgagatc cacatcttct
    16201 cccaagtcat ctggagcgat ttcgttgatt tctgcatcat aagcttccac ttcatttttt
    16261 tcatcatctg gattttcatc atcgtatgaa agagctggat ctgcttcgta tgcatcttcg
    16321 tcttctggat catctgcatt gtagtcaatg gcatctgaat caccatccat aaaggcattg
    16381 acacgttttt tcttagcttt tggtgctact tcatcgtcgt cattttcttc aagagcgatg
    16441 atttcttcgt cgatttcgtc cacaccatac catgaacgaa gaccccattt gttgtcccca
    16501 agtgagatga agctaccgtc aaagttcaac tctgtgtaga acagaggcaa agcttcgcgg
    16561 atatcgctgt ttgatgttcc aaggtagttt tgaatttcgt ttacaagatc gctaaaatgc
    16621 atctcatgat cgcgaccacg aagttctaat atagcacgcg ctacctcaat catagatagt
    16681 tcactttttt cttgcccagc aaatacttct aattccaaag cgtttctcct catttatact
    16741 actatcgcca gagcgaacag actctgacct cattttatca tttactcttt attttacgat
    16801 aattttgcgg aatagtcaaa ggttaagggg gagaaagtgg caggattaga ctaattccaa
    16861 tataaaactc cttccttttt ctgttgctcc attttccaca aatccaagcg acttgaaaca
    16921 cctcctagaa gcatgattgt aggtgtagat ttccttgact ctcaattctt tccatccttt
    16981 tactcgagcc aattcaatca aagcacttag aatctttttt ccaagtcctc gatgttggta
    17041 agcggaattc ccaatcacaa tggggagatt atcctgagat agtgtaatat ccccaattgg
    17101 aaaccattct cccttctcct tgacttcaat ccaaaaaagc tcaccatgcc gatccaaata
    17161 ggaatacatg gcttccaagg tcgcttgact gtaaggaagc ttcaccccat ctacgaggta
    17221 aaccaagttc acatcctgat accaagcaaa agcttcctca caatgattga ccttataata
    17281 aggaacaaaa cacaatgcac taccttttca acaaaagagt tgctgcttga ttaaaaccat
    17341 cacaccagtt ataccatttt gcttcatacc catcttgagc taggatacga tcttctaaat
    17401 caaaaacaga gtaaatcttt ctttcctcgc aagcttgcgc atagagatga tatagttcat
    17461 caccaccatc tctatcccac tcagcagaaa tcgtatcccg atctgccaat aaagtctgat
    17521 aagccctgtg atgcccatct gtaatcagca aacaatctcc aaaggcaaga atactgattg
    17581 gatcgacttg gattgtttct gccgactggt aaagcatctg aatatcttgc aacttctttt
    17641 ctgataaata tagttgagtc ggatgaagat ctgctatgtt gactttcatt tctttctcct
    17701 caagggaatt cgatactcac ttctgtttgc ctttaaatcg ccattggaag cggagcttgt
    17761 catagaaggg aaactcgata aacaggactc ccaagcccac acagagactg gcaaggacgt
    17821 ctgatgggta atgaactccc agatagactc ttgataccag cacactgact aggtagaggc
    17881 caaggacgat ttgtacgatt tttctccaga ctggatcttt aatccgctga ctaagaataa
    17941 caatcaaagt acctaccatc aaggttacag ccagagaatg cccacttggg aaggaaaatc
    18001 ccttctcctc caccagatgt aagatatctg gccgtgggcg ctggtagata tttttaaagg
    18061 tcacgattaa aagacctgcc aaagccagat ttcccagcat gaagaaactt tctatcttcc
    18121 atcgcttacg ataaaagaca aaagctgtaa tgacaaccca agtgataatc actgggatat
    18181 caatcagacg tgtgagggct cgaaaaagaa tagtcaaata atctggtaag tctcctcgaa
    18241 tggcagtctg aatcgattgg tcaaaattga ccagcgtttc agggtaaaat ttgaccatgt
    18301 agccaagaat aacgaaaagt aaaagggcaa aactgccctt cattaaaaat gtttgtttat
    18361 ctctcataat gttttaaggt tggtttcaag agaacataca acaaccagaa tgaaacggaa
    18421 aagataacac cttcaatcaa gttaaaaggt aataccatgg tcattaggta gttggaaagt
    18481 cccaaaattt ttccaatatc aaagttagca aacttagcgt acaaaggaac agcataaaca
    18541 tagttgagaa ccaacatggc caaggttaaa ccaatagttc cagctagaga gcctagtagg
    18601 aaacgaaggg ttgtccgttc ctttttccaa atcaaagcaa atacgatgac aaaaactccc
    18661 aaagctacga tattcatcgg caaaccaatg taagtattca ctccttggct gttaagaagc
    18721 aacttcaaga gtgagcgaag caagagcact cctagagcag caggcaaatc catgaccacc
    18781 agacccacaa ggactggcaa gatactaaat tcgatcttga ggaaagatgc cgctggtaaa
    18841 agcggaaaat caaagtacat cagcacaaat gagatggctg atagaattgc aatggtcgaa
    18901 agtcgacgtg tgtttgtcat aacaggttcc tccaattttc tataaaatca gaagaagttg
    18961 gaaaggattc ctctatctat tctcactttt tatatcccaa aagttccctc ttactctatt
    19021 aaagaaaaac aaagcaagtg gttacaatcc ggctataaat ctatcaaaac agacaaagct
    19081 attctttcgt cttctcccat ccagactata ctgtcggttg tggaatctca ccacatcagc
    19141 ttgcgctcgc ggacttcttt aaagggaaag aaatagagat ttttctttta gactaggcga
    19201 caagctgtag gcataacttc tggttaggca aagcttgtca acaaagtata aaaggaaaag
    19261 atcatttcct agttaaagtc accgccggtc gggaatcaca ccctgccctg aagactcttt
    19321 tatcataaca aaaaacgctt gcaagcgcaa gcattttgtt cattttcatt ttttatttca
    19381 atttatccac ttcataggta tggacgagct caagacctgc aaagttctgc tggcgaagag
    19441 cctcatagac aatcatgcag acggtattag acacattgag actgcggaca tgttcatcat
    19501 tcatgggaat acggagagcc ttctcaggat gttctcgcat aaaatcttca ggtaagccct
    19561 tgtcttcacg tccaaagaga aaataatggt cctcgtcagt cgataaatcc acctcagaat
    19621 agattttttc cgcgaatttc gaaatcagat agagttttcc cttcatctga gatatgaaat
    19681 cttctaaact ctcgtaaaaa taaatctcta gcttatccca gtaatccaat ccagcccgct
    19741 tcatcttgcg gtcatcaata ggaaagccca taggcttgat gatgtggagg ggagaattgg
    19801 tcgcagcgca agtacgcgcg atattgcctg tattttgtgg aatttgaggt tcaaataata
    19861 caatgtgatt tgtcatgact tgcttccttt caccattgca aaaaaatagc cacactgccc
    19921 ggagtcaagc tcagcaaaca gcgtggttaa ggcatcgtta acttacctca caacaggttt
    19981 gaagtaaatc agcgaaacta ctttcttagt ataacacttt cagaatcatt gtcaatagaa
    20041 atgacttgat tttttcaatt ttttcaagct atttccaagg gttgtaaaat cgtccctgat
    20101 tctgcaagat aagtagtaaa ctaactacta aaaacaaggt tgccaagagc aaggtaatat
    20161 agtctccttt tttcaaggcc tgataactat accatgtgcg ttttttctct ttcccaaagc
    20221 ggcgaagctc catggcagtc gcaatggtat caatgcgttc tagcgagcta aaaatcaagg
    20281 gcgtaataat gagcagattg cctttgattc gttgcataag agaagctttc ttggataatt
    20341 ccatcccacg cgcctcctga gacatcttga tagtaaagaa ttcttcctgc aaatctggaa
    20401 tatagcgcaa ggtcaggctg acagaataag caatcttata gggcacacca atttgattta
    20461 aactggaagc aaactgacta ggatgggttg tcatcaaaaa gataatagcc agaggaatgg
    20521 tgcaaagata cttaatggcc aaatttagca gataaaagag ctcctggctg gttagagtgt
    20581 agacaccgat tccctgccaa atcacacttc tctctccata aagtccaacc ccatactcgg
    20641 gagaaaagag atagaccatc aaaacgttta aaacggcaaa taccgtcgca aaaacggcta
    20701 caaaggaaac atctttaaag cgaatttctg ataaatagag gagaaagact gaaaagatgg
    20761 caatcagcaa gagcattctg gtatcatagc taatcatggc cgccaatgat accagaatga
    20821 aaaagagaag tttcccagct cctgacaagc gatgaatcac agtatctcta tgctggtaac
    20881 cgattaattt agcttgcatc cctctctcct ttctttgtaa aatgccgtta aatccagtgg
    20941 atccacatct agtttcttag ccaagttaaa gatggaggtt tcttttagat tggcttttac
    21001 taacagctca ggatcgctca acagactggc tggaacagta tcggcaatca attctccatc
    21061 caccatgaca aggacccggt ctgaataatc cagcatcaat tgcatatcat gggtaatcat
    21121 gacaatggta tgcccttttt gatgtaactc ttcgagaaat tccataatct cagtatagtt
    21181 cttctgatct tgacctgcag tcggttcatc taggagaata atttcagctc ctaagaccaa
    21241 aattgaagca atggtgacac gttttttctg accaaatgac agggcagaaa taggccaatt
    21301 acggaattca taaagtccac agattttcaa ggtttcatag actctcgttt caatttcctt
    21361 ctcatccaca cctcgcaaac ggagccctag agccacctca tcaaaaatca tattggttga
    21421 aatcatttga ttaggatttt gtagcacata gcctactcgt tccgcccgct ctgcaacaga
    21481 atcgcctttt atatcctgtt tttcccaaag atagcgtcct tccgtctgaa taaagctact
    21541 tatagccttg gctagagttg atttccctgc tccatttttt ccgacaatag caatcttttc
    21601 acccttttta atatctaaat gtagggattt taaaatcggt ctatcatcat aagagaaaga
    21661 cacgtcctct aatttaaaga gtgactgcaa ttctggagtt tcttttgcca gttcattctg
    21721 cagctgaacc tgaccttttg agatagacat gttatccaga ttcgctaact gttcttcctt
    21781 gactaagtcc acacctaatt gacggagagt cgttagataa aggggttctc gaattccatt
    21841 ttgagtcaat aaatcagtcg caagcaactg gtcagggctc ccattaaaaa ggatacgacc
    21901 atcgcttatc aagacaatcc gatccacagg gcgatgcaga acatcctcca aacggtgctc
    21961 gataatcaga gtcgtcgtcc cctcttcctt atgaatctgg tcaatcaatt cgataatatc
    22021 ctgacctgac ttgggatcta gattggcgag tggctcatca aacaagagaa tcggactttc
    22081 atcaatcaag acaccagcca gactgactcg ctgcttttgt ccacctgaca aatcctgagg
    22141 acgctgatcc agtaaaggaa gaaggtccag cttttcagcc catttataaa cacgaccttt
    22201 catctcatct agggctgtca catcattttc cagagcaaac gccaaatctt ctgccacaga
    22261 caagccaata aactgcccat ctgtatcctg caaaactgtg ctaaccagat gagacttatc
    22321 atagatgctc atatcaaagg ctacttgacc ctttatcaaa aattctccat atgtctgacc
    22381 cttgtaaata ttgggaataa tcccattcaa acactgaccc aaggtagatt tacctgaccc
    22441 agatggtcca acaattaaga ctttctctcc cttgtaaatg gtcaagtcta tcccttgcaa
    22501 ggtcggttct tgttgtgttt cataccggaa agagaaatcc ttccactcaa ttatagcttc
    22561 tttcatctta ctctcttcat tcgcttctta gacttctatt ttatcataaa tcaagccctt
    22621 cttgcagtct cttctcttaa aatcttagcg ccaaaaagat tcctatccta gcttacttgc
    22681 ctaactaatc tataaacatc gaaaaagact agttgcccag ccttccccat cattttatac
    22741 tcttcgaaaa tctcttcaaa ccacgtcagc ttcgccttgc cgtaggtatg gttactgact
    22801 tcgtcagttt catctacaac ctcaaaacca tgttttgagc tgacttcgtc agttctatcc
    22861 acaatctcaa aacactgttt tgagcaacct gcggctaact tcctagtttg ctctttgatt
    22921 ttcattgagt attagtcctt tttcaaactt cctgcacgag tttgggttcc tgcataggca
    22981 agtaagagaa gagttcctgc aatagctaca gatacaccat tggcaattcc cgcaacaatc
    23041 ccttgtgcaa atactttttc tgccgcttct tgataaatca caacatctcc aagtggtgcc
    23101 aagacacccc aaacaagggc atttgcaagt agttgaatga ggttaaaaat aagaatatct
    23161 ttccagtcaa aaacaccatt gatcactcga acgtactttc taaaaagtcc cacaactaga
    23221 ccaaagagtc cgctagcgat aatccaagtc caccatagac cataaccagc aagagagtcc
    23281 ttgattgcat gaccaatcaa cccgacaagc aaaccgataa tcggtccaaa aataatagaa
    23341 agtagcgctt gtaccgcata ctgaagctgg atgcttgtat ttggaacagg ggttggaatg
    23401 ttgatcatcc cgatgacgac aaagagggca gcgccaattc cgacagcaac aacttgttta
    23461 attgtaaatt tgatttccat actattctcc tattttatcc ttctattttc tttatttcaa
    23521 tggtccaaga tgaaccgaca cctacattat aggccttggc aaaggaacct tggttgatag
    23581 ccaaacctaa acgatagaga gagttgatgt aaaggatggg ttgcccaatt ctcacatctg
    23641 caaatgattt gccatagaca acctgatttt gatagaccag catatcagca tgatagatgg
    23701 tcacttcaaa acgatcacca aattctggtt ccagcttgta aaattcttcc cgtgtgatag
    23761 aggtccaaag cgaaccgaaa cgcacatcca gaatatcaat ggctcccttc accagatgat
    23821 cttctatgat ggtcgctacg actggaagct ctacaatctg ttccacactg agctctggcc
    23881 ctacttcctc aaaagtaatg tgaccactgg ccagtttagc accagtatag gcatagacat
    23941 cacgaccgtg gaaggtataa gaatgctctg tgttttgacg cctattggcc acctcagaaa
    24001 tctcacgaat ggctacaatg ccaacgtgtt tcttgataaa ggaaagcgtc ccattatctg
    24061 gcgtgacaat gtattgattt tttgcagtct tggcaactac actcttacgt ttcgaaccga
    24121 cacctggatc gacaaccgat acaaacgtcg ttccctcagg ccagtaatcc accgtctgaa
    24181 agagacgata gctcccctca aaaatattat aaggcgtgat atcgtgcgtc aagtgatgga
    24241 tttttaaggt tggagactct tctaaagcca ctccaatcat agccgacacc gcaccatcaa
    24301 ccagaccaaa gtctgattgt aataccagta aattattgtt cattttatct ccttgtatat
    24361 cctttatcat accatatttc agagaaagtc gctaatagct atttcaattg gttagggtat
    24421 agttttacct tatagcgaat tttcactaaa agctcttgtt attagctagt aggtgcattt
    24481 tttcttgaaa aagggtatga tagttacatc atgaaaaagt aggttttatt atgaaaatta
    24541 tccttgtcgg agggggaaaa gttggttttg ccctctgtcg ctccttggtt gcagaaaagc
    24601 atgatgtttt gctgattgag caagacgaag ctgttctcaa tcatattgtc agtcgctttg
    24661 atatcattgg tatccttggt aacggggccg attttgccat tcttgagcaa gccagcgtcc
    24721 aagattgtga tatctttatc gccctgactg agcacgatga agtcaacatg attgcagcag
    24781 ttctagccaa gaaaatggga gctaaagaaa ctatcgttcg ggtgcggaac cctgaatatt
    24841 ctaactctta tttcaaggaa aagaatattc tcggtttttc tcttatcgtt aatcctgagc
    24901 tcttggctgc ccgcgctatc gcgaatatca ttgacttccc caacgccctg tctgtcgaac
    24961 gctttgctgg tggacgcgtt agcctcatgg aatttgtcgt caagtccacc agcggtcttt
    25021 gccaaatgcc catttctgat tttcgtaaaa aatttggtaa tgtcattgtc tgtgcgatag
    25081 agagggatca tcaaattatc attccaagcg gtgacatgac tgtacaggat aaagatagaa
    25141 tctttgtcac tggtaaccgt gtcgatatga tactcttcca taattatttt aaatcacgcg
    25201 ccgtgaagag ccttctcatc gttggagcag gtagaattgc ctattatcta cttggtattc
    25261 tcaaagatag tcgtatcgat acaaaagtca ttgaaatcaa tcctgaaatc gccagcttct
    25321 ttagcgagaa attcccaaat ctctacatcg ttcaaggaga tggaaccgca aaagatatcc
    25381 tgctggaaga aagtgctcaa cactatgatg ccgttgcgac tctaacagga gtcgatgagg
    25441 aaaatctgat tacatctatg ttccttgaca gggtaggtgt acagaaaaat attactaagg
    25501 tcaatcgtac cagtctcctc gagattatca atgcgcctga tttttcaagt atcatcacac
    25561 ctaaaagcat cgctgtagat acgattatgc actttattcg tggtcgagtt aatgcccagt
    25621 attcagacct tcaagccatg caccatctag ccaatggcca aatcgaaacc ctgcaattcc
    25681 atatcaagga agccaataaa atgactgcca aacctctttc tcaactgaaa ttgaaaaaag
    25741 gggttcttat tgcagccatt attcgaaagg gcaagactat tttcccaact ggggaggata
    25801 tgttggaagt tggagacaag ctcctagtaa caaccttgtt gccaaacatc accaagattt
    25861 atgacttgat tgcgaggtaa gaaatgaata aaagtatgat tcgttacctc ctttcaaagt
    25921 tacttttgat tgaagctgtt ctcctcttgg ttcctgtggc tatcgctgtc tattaccgtg
    25981 aatcgagcca agtctttaca gccctctttt cgaccatagg gattctcgta ttgttaggcg
    26041 gttcagggag tttacagaag ccaaaaaatc aacggattta tgccaaggag ggagtcttga
    26101 tcgttgccct ctgttggatc ctttggtctt tctttggtgg tctccccttt gtcttttctg
    26161 ggcaaatccc tagccttatt gatgcctttt ttgaaattag ttctgggttt acaactactg
    26221 gagcaagtat tttgaacgac atttcggttc tcagccgttc cctcctcttc tggcgaagtt
    26281 ttacccactt gattggaggg atgggagtgc ttgtttttgc acttgctatt atggacaatg
    26341 ccaaaaatag tcacctagaa gtaatgaagg ctgaggttcc tggtcctgtc tttggtaagg
    26401 ttgtatccaa attaaaaaac actgcccaga tcctctatct cctttacata gccctctttt
    26461 ccctctttgt catcatctat tatctagccg gtatgcctct ctacgatagt tttgtcattg
    26521 ctatggggac agcgggaact ggaggattta ccgtctataa cgatggaatt gcccactatg
    26581 gtagctcact gattacctat ctggttagta taggagtttt ggtttttggg gtaaatttca
    26641 atctctacta ctaccttatg ctccgtcggg ttaaggcctt ctttggagat gaagagcttc
    26701 gggcttactt ggtcatcgtg ctggtttcta caggcttgat tagcctcaat actctctacc
    26761 tctacccagg gttttcaaag agctttgaaa tgaccttctt ccaggtttcc aacatcatta
    26821 caacaactgg ttttggatat ggagatatta ccaactggcc cctcttctcc cagtttatcc
    26881 tccttttcct catggcaatc ggtggctctg ctggatcaac tgcaggtgga ctcaagatta
    26941 ttcgaggcct catcctttca aaaattgcca aaaaccaaat tttgtcaatc ctatcgcccc
    27001 accgtgtttt gaccctccat gttaataaaa tggtgattga caaagatacc cagcataaga
    27061 ttctcaagta ctttgtcatc tatgctatga ttttgctagc gcttatcttt attgtcagcc
    27121 tagatagcaa tgattttctg gtcgtgacca gcgctgtctt tagctgtttc aataatatcg
    27181 ggcctattct aggaaccact tctagtttct caatctttag tcccatctca aaaattctcc
    27241 tctcctttgc aatgattgca gggcgcttgg agatttaccc aatcctcctt ctctttatga
    27301 aaagaacttg gtctaagaga taaaatacaa aatccctctt tttacaattg tgaaagaggg
    27361 atttttatat taaaaagggg gaacgttttt aaatccaagc ctgtctgtaa gcaaagttct
    27421 tactcaaata aaagatggaa aaacttacta cacagcttgg taatgctcca atacaaattg
    27481 taaggcttta cttggattct ttgttaaatg aatatattcc attcctctgg tagcaactat
    27541 ctgaatacct aatctttctg catccacctt catctctcta taataactcc gaacttgtgg
    27601 agccagaata attaaatcat aaacacccat aatatcataa tgagctccgt acgctcctga
    27661 attcgcaatc actctaactt ctgctaattg agcgccctcg ttaattgcat tggctaatta
    27721 cgcacttgtt ccagaccctg cacaaagaac cagtactttc aactccttac tttttattac
    27781 atctatctca ccaggcatta tttcacttgt atcctcctct aaaataatat catttgagct
    27841 tgcaatatct acaacctgta gtagatatct cgtatttaga caatatgaaa acaagacgac
    27901 ttccatatag gaaaccgcct tctctctatg ttgagtgatt tatattaaaa taacttttct
    27961 tctagctgca ttttattatt ataaaaacat tcatcataac cctgaactta aataacgatt
    28021 tttattcaag atacatactc ctagaataaa ctttatatga aattctcatt tttgttttta
    28081 caattctcct tagttaaatc ttgtttaata tatgttttac atatagtatt tagcgccaca
    28141 tagtactgaa ctctctccaa aaacggttat tcctctttga atagggcgtt atcacaagaa
    28201 aagcatctcc acgtttcaac ttcatatggc tcaaaaacaa tcaattgatg ctaaaacctg
    28261 tacctagatg tttcggttca taaaaccatg aaactgtaaa agtggatgaa attgatagcg
    28321 atagtcaaat caagaggcat cataactcta aaaagtcaca atatataagt tcatcctcgg
    28381 aaaaatatca ttctaattgt tgaaatgcct acatgaaaag aaacgtcaaa tgctcatgaa
    28441 acaacgaata caggtatcaa aactatgaca aaacaagtcc ctaaatttac taaagacact
    28501 gctcaacttt acacctgtaa atggttgttg tataataaag ttacaaagat gtacgaccac
    28561 actgttgtaa atcatagtgt tcgcgaatat attactgata gcatttctac aaatacaatt
    28621 gaagagactg gatagacttt aaacgaaata tgtcagtgtt ttggcattcc tagccttcat
    28681 atcatttaaa gaattctata gacaaaattt ttcccaatac agacactcgt aacaactgct
    28741 tcatttttct accaacatat ttaggaacag gataagatac aagaggatta atccatagat
    28801 cagttctata ccaatctaag acaaataagc taaaaaaacg attgataata agcaaataga
    28861 ttccaaattt tctctatctg ctcattttaa taaacaatac tagtgtaact atccttccag
    28921 tcagaagctt gtcaaatcac accgaaaatt cttctaaaat ttatctcgtt aggcaatcaa
    28981 gcaaaaactc gacgatagta caaacattat catacagaat tgacttccta aattatatac
    29041 tttagtaagg ttttcggata agaaaaaagg ttcattttac atttctaaac attcttttct
    29101 aagatgaaaa acagaatttt tcgattgtaa tttaaagcaa caagaagatt ttcagtatca
    29161 tcctatagat acgagctaat taagaaaaac tacatttttg aatataaact acaataatat
    29221 aaactaaatt ttataggagg aagacaatgg attggtacga ttatatgata caggcatcca
    29281 aacaatcaca attcaacgca agccattggt ttcgctattt gcgaaaagtt atttttgaag
    29341 actattctta tttaacaaac caagatgtag aaaagttgct agactccaaa gaactaaccc
    29401 gttttcaaaa aattagcttg aagtatgcct ttcaagagca tactccaact cataaatatg
    29461 tgatttcatt aaataaacct gctaagttaa ccaatgttca aaaattgatg gagaaataca
    29521 aacatggata aaatgaaacc ggtcttccaa gccctaaata agaaattaat tcaggaaaat
    29581 ctgactttaa caattatggt tatgtcttag aatatcatgg tttacgtgcc acacaagatg
    29641 ttgatgcttt ttatgaccaa aatcagaaaa tcaatgaaat tattgctcgt gtaggaaaac
    29701 agtttaatct taacatccac gaagagttat ggctcaacaa tcatgttgca aagcaaatat
    29761 gaacaaacaa cctcccttaa gtttatgcga atccttgtac tcatttgaga atctgaccgt
    29821 tttagtagtc cctattgagt atgtgttagg aatgaagatg atgagtatca gagagcagga
    29881 tttgaaagat attggtgcaa ttattaaata caaaaacttt cattcaccat tcgatacctt
    29941 taaatattta aaagacatgg gatttgatac tattgacctc tctgttctat tagaaggttt
    30001 tagttatgct tatggtatgg attggttaga aaaatttttt aaagaaaatc aagataaact
    30061 tcgcgaattt tattaacagt atcaaacaag atgattgtca attagccagt cgtcttattt
    30121 ttatgatgga atgaaataaa atcggaacaa atcacttaga gaattccagt caatttctag
    30181 cactgtttga gacgtttcag cggactatag taaaatgaaa taagaatagg acaaatcgat
    30241 caggacagtc aaatcgattt ctaagaatgt tttagaagta aaggtgtact attctagttt
    30301 caatctatta tatttcagat tcggtccact attccttccc aaaaacattg catattgcgc
    30361 cgaaggaatt gctcacacta tcccaagcac aaaaccctca gtcgattgac cgagggttcc
    30421 tttttattat tcaagaactt gattagctca atgcatccaa ggcatcatcc attgaaagaa
    30481 cttcgtggaa gacacgttgt gtcaattcag ttttttgctc tggagtgagg tatttagtgt
    30541 ttacacagta tccagagata cgtacgataa cgtcttcgcc tgacatgatc tttttgtaaa
    30601 catcgttcaa gtccataacg ttcaagttaa cgtgttgtcc accgttttca aagtaaccat
    30661 caaggattgt taccaagtta tcaacttgtt catcacgagt cttaccaaga gcgcgaggtg
    30721 atacttgtgt agtcaatgag ataccgtcag ctgcataact aaagtcaagg ctagaaagtg
    30781 agttcaagtt ttgcaaccaa ccacctttag ctttgttaga tgggttagca cctggtgaga
    30841 agaattcaag tttagacaag ttcacagaac catcttcgtt gaggtataca cctttgtgaa
    30901 ctggtgagtt accagtttgt ttagagtaag caacgttaga tgtgattgtc aaaagtgata
    30961 ctgtagcttc tgcgtctttg tatagtttgt ggctacgtag acgagttgtg taagcttcga
    31021 tcaaccattc tgccaattcg tttgaacgtg ggtcatcttc accccagcgt gggtagtcac
    31081 cgattgtttc gtaatcgtag atgtagccat cttcatcacg gattggttta actgtagcgt
    31141 atttgatagc tgacaatgta tcaacagtgt tagcaaatcc acagataccg aatcccatgt
    31201 tggcacgttg tttagttggc aagaaggcca tttgaacagc ttcgtagttg tacctatcag
    31261 tcatgtagtg gatgatgttc aaggcatcta cgtaagtgtc agtcaaccag tcaagagatt
    31321 tttcaaagtt cgctttaact gattcgaatt caagaacttc gtcacggatt ggttcgatat
    31381 caaatacttt gtagtctttg tgaacatcgt cgtaaccacc attcaaacca gtaagaaggg
    31441 ctttaagaac gtttacacga gcaccgaagt actggatgtt gtggcgttgt tcttcatttt
    31501 ctggatcaag tggagacaca cagcatgaga tacagctcat ttcaccatat ccgtctttag
    31561 ccattgttgt tacaccttcg tattggatag aagagtgttt gtggctcatg tgcatacagt
    31621 agcgacggaa gttgtatggc aatttgtcag tccaaagaac tgtcaagttt ggttctggtg
    31681 agttaccgat gttgtcaaga gtgttcaaga aacggtagtc catcttagta acacggtgac
    31741 gaccgtcgtt acccatacca gccatagaag ttgtgataaa ggttgggtca cctgagtaca
    31801 attggtcata agcttttgta cgagcaaatt taactgtacg aagtttcata acgaaatcat
    31861 caacgaattc ttggatttct gattcagtaa atgtaccacg agcaaggtca cgttctgcaa
    31921 agatgtccaa tacgattggt acacgaccta gagatgtagc agcaccgtta atcacacggc
    31981 agacagccat gaaagcaatg ttaacccatt ggattgcttc tttcacgttc atcgctggtt
    32041 tgcgaacatc aaccccgtaa aggtcaccca ggcgaacaac ttgttgcaat gcttggtatt
    32101 gaaggtttac ttcttcacga agacggattg tttcttcatc gatttctttg attgcattcc
    32161 agtcatttac tttttcttgc atcaagtagt ctgcaccgta aagagcaaga cgtgcgtaaa
    32221 caccgatgat acgtccgcgt gagtatgcat ctggaagacc agttacagtg tgtgcgtgac
    32281 gagcgcgacg aatatttgaa gtgtaggcac ggaaaatacc gtcgttaact gttgttacat
    32341 atttagtgaa gatttcgtga acagctgggt ctggttcgta tccattttct ttcaaagtag
    32401 tttcagccat acggatacca ccttttggca tgaagttcaa tttgaagagt tcatcgtttt
    32461 ggataccgaa gataacttca ttttctttgt cgataaatcc agcagggata tcagcgatag
    32521 atgttggacg agtgtccatt gggaaacgag tttcttcgta gtgtgcttta gtttcttcta
    32581 caattttctt gatgtgaagt gaacgctctg ttggtcctgc aaggaagctt tcgtctccat
    32641 cataaggtgt gtagttagct tgtacaaatc gtgatacact tgctttttct ttccaatcta
    32701 cgcctttgaa gccttcccaa gctttgtcaa aaatatcttg tgcttcaaca actgtcttaa
    32761 caaccatatt aatgtcctct tttttctagt aacagtcatc tgttacattc ataagacaag
    32821 tataccatat agtaaccgat ttcaacaagt gaaaattccc tatttttaca ctttcttttc
    32881 taaaacagtc tatattttat ttcaaactgt attatatttt tgaaaaaata aagtcctttt
    32941 ttcttttttt cagaaaaaag ggtataataa aagaaaataa gcagtaacac tcaatggaaa
    33001 tcgaa
//
LOCUS       DAVHTH010000021        32695 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.021, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000021 DAVHTH010000000
VERSION     DAVHTH010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 32695)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32695)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32695
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.021"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            complement(384..1073)
                     /gene="rplA"
                     /locus_tag="VVR63_001006"
     CDS             complement(384..1073)
                     /gene="rplA"
                     /locus_tag="VVR63_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HEU6129034.1"
                     /translation="MAKKSKQLRAALEKIDSTKAYSVEEAVALAKETNFAKFDATVEV
                     AYNLNIDVKKADQQIRGAMVLPNGTGKTSRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINDGWLDFDVVIATPDMMALVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADRAGNVQAIIGKVSFEAEKLVENFKAFNETIQKVKPATAKGTYVTNLTITTTQ
                     GVGIKVDVNSL"
     gene            complement(1281..1706)
                     /gene="rplK"
                     /locus_tag="VVR63_001007"
     CDS             complement(1281..1706)
                     /gene="rplK"
                     /locus_tag="VVR63_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HEU6129035.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFTFVTKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTR
                     AQVQEIAETKMPDLNAANVESAMRMIEGTARSMGFTVVD"
     gene            complement(1829..2545)
                     /locus_tag="VVR63_001008"
     CDS             complement(1829..2545)
                     /locus_tag="VVR63_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HEU6129036.1"
                     /translation="MKKRYVILSGLLALTLAACSQEKTKVEENTQKTEQSSQPEGTVG
                     SKSQASSQKKAEVSNKGSYYSIQGKYDEIILANKRYPLSKDYNPGENPTAKAELLKLI
                     AAMQAEGYPISDQYSGFRSYETQAKLYQDYVNQDGKEAADRYSARPGYSEHQTGLAFD
                     LIGTDGDLVTEEKAAQWLLDHAADYGFVVRYLKGKEKETGYMAEEWHLRYVGKEAKEI
                     AASGLSLEEYYGFEGGDYVD"
     gene            complement(2563..3024)
                     /locus_tag="VVR63_001009"
     CDS             complement(2563..3024)
                     /locus_tag="VVR63_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000335612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEU6129037.1"
                     /translation="MCLICQRIELIKAGQNPYFVKELETGYVVIGDYQYFKGYTLFLA
                     KDHVTELHHMETSVKLRFLEEMSLVQEAVAKAFEAEKMNIELLGNGDAHAHWHLFPRR
                     AGDMKSHGLNGRGPVWWVPWEEMAAEDCQVQSPELEEMIKILSHELEKYLA"
     gene            complement(3026..4063)
                     /locus_tag="VVR63_001010"
     CDS             complement(3026..4063)
                     /locus_tag="VVR63_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HEU6129038.1"
                     /translation="MNQTVEYIKELTAIASPTGFTREISNYLVKTLEGFGYQPVRTAK
                     GGVNVTIKGQNDEQHRYVTAHVDTLGAIVRAVKPDGRLKLDRIGGFPWNMIEGENCTV
                     HVASTGQKVSGTILIHQTSCHVYKDAGTAERTQDNMEVRLDVKVSNEKETRALGIEVG
                     DFISFDTRTVVTDTGFIKSRHLDDKVSAAILLNLLRIYKKEKIELPVTTHFAFSVFEE
                     VGHGANSNIPAQVVEYLAVDMGAMGDDQQTDEYTVSICVKDASGPYHYDFRQHLVALA
                     KEQDIPFKLDIYPFYGSDASAAMSAGAEVKHALLGAGIESSHSYERTHIDSVIATERM
                     VDAYLKSEAVS"
     gene            complement(4161..5486)
                     /gene="brnQ"
                     /locus_tag="VVR63_001011"
     CDS             complement(4161..5486)
                     /gene="brnQ"
                     /locus_tag="VVR63_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HEU6129039.1"
                     /translation="MAKKGTLTGLLLFGIFFGAGNLIFPPSLGALSGEHFLPAIAGFV
                     FSGVGIAVLTLIIGTLNPKGYIYEISTKIAPWFATLYLSVLYLSIGPFFATPRTATTA
                     YEVGISPLLSDANKGLGLIVFTVLYFAAAYLISLNPSKILDRIGRVLTPVFAILIVIL
                     VVLGAIKYGGTSPQAASAAYQASAFGTGFLEGYNTLDALASVAFSVIAVQTLKQLGFS
                     SKKEYISTIWVVGIVVALAFSALYIGLGFLGNHFPVPAEAMKGGTPGVYILSQATQEI
                     FGSTAQLFLAAMVTVTCFTTTVGLIVSTAEFFNERFPQISYKVYATAFTLIGFAIANL
                     GLDAIIKYSIPVLVILYPITIAIVMIVIVNKFVALSKPGMQLTIAVVTVIAIASVLGS
                     SFKVEFLANLVSVLPFAKASLPWLVPAIVGILLSLVLPNKQESDVFEME"
     gene            complement(5657..5749)
                     /locus_tag="VVR63_001012"
     CDS             complement(5657..5749)
                     /locus_tag="VVR63_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEU6129040.1"
                     /translation="MRSARACQFLLEQGYNVINVQGGMLAFEEL"
     gene            complement(5792..5944)
                     /locus_tag="VVR63_001013"
     CDS             complement(5792..5944)
                     /locus_tag="VVR63_001013"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEU6129041.1"
                     /translation="MKEIAFDAFYQLYQNDQLSLVDVREVDEFAALHLECAHNLPLSQ
                     LADSYD"
     gene            complement(6104..6682)
                     /locus_tag="VVR63_001014"
     CDS             complement(6104..6682)
                     /locus_tag="VVR63_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HEU6129042.1"
                     /translation="MSQIERIKQAIMADSQNASYTERGIEPLFAAPKTARINIIGQAP
                     GLKTQEAGLYWKDKSGDRLRDWLGVDEDTFYNSGYFAVLPMDFYFPGHGKSGDLPPRT
                     GFAEKWHPQLLQELPDIQLTLLIGQYAQAYYLQEKISGKVTERVKHYKDYLPAYFPLV
                     HPSPRNQIWMAKNPWFEAEVVPDLKKRIKTIL"
     gene            complement(6736..8136)
                     /gene="pepV"
                     /locus_tag="VVR63_001015"
     CDS             complement(6736..8136)
                     /gene="pepV"
                     /locus_tag="VVR63_001015"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HEU6129043.1"
                     /translation="MTAIDFTAEVEKRKEDLLADLFSLLEINSERDDSKADAQHPFGP
                     GPVKALEKFLEIADRDGYPTKNVDNYAGHFEFGDGEEVLGIFAHMDVVPAGSGWDTDP
                     YTPTIKDGRLYARGASDDKGPTTACYYGLKIIKELGLPTSKKVRFIVGTDEESGWADM
                     DYYFEHVGLAKPDFGFSPDAEFPIINGEKGNITEYLHFAGENTGVARLHSFTGGLREN
                     MVPESATAVVSGDLADLQAKLDAFVAEHKLRGELQEEAGKYKVTIIGKSAHGAMPASG
                     VNGATYLALFLSQFGFAGPAKDYLDIAGKILLNDHEGENLKIAHVDEKMGALSMNAGV
                     FRFDETSADNTIALNIRYPKGTSPEQIKSILENLPVVSVSLSEHGHTPHYVPMEDPLV
                     QTLLNIYEKQTGFKGHEQVIGGGTFGRLLERGVAYGAMFPDSIDTMHQANEFIALDDL
                     FRAAAIYAEAIYELIK"
     gene            complement(8149..8754)
                     /locus_tag="VVR63_001016"
     CDS             complement(8149..8754)
                     /locus_tag="VVR63_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HEU6129044.1"
                     /translation="MKFLELNKKRHATKHFTDKPVDPKDVRTAIEIATLAPSAHNSQP
                     WKFVVVREKNAELAKLAYGSNFEQVSSAPVTIALFTDTDLAKRARKIARVGGANNFSE
                     EQLQYFMKNLPAEFARYNEQQVSDYLALNAGLVAMNLVLALTDQGIGSNIILGFDKSK
                     VNEVLEIEDRFRPELLITVGYTDEKLEPSYRLPVDEIIEKR"
     gene            8925..9725
                     /locus_tag="VVR63_001017"
     CDS             8925..9725
                     /locus_tag="VVR63_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU6129045.1"
                     /translation="MKKFSLLLAILPFLVACGNQATPKETSAQKTIVLATAGDVPPFD
                     YEDKGNLTGFDIEVLKAVDEKLSDYEIQFQRTAWESIFPGLDSGHYQAAANNLSYTKE
                     RAEKYLYSLPISNNPLVLVSNKKNPLTSLDQIAGKTTQEDTGTSNAQFINNWNQKHTD
                     NPATINFSGEDIGKRILDLANGEFDFLVFDKVSVQKIIKDRGLDLSVVDLPSADSPSN
                     YIIFSSDQKEFKEQFDKALKELYQDGTLEKLSNTYLGGSYLPDQSQLQ"
     gene            complement(9909..10742)
                     /locus_tag="VVR63_001018"
                     /pseudo
     CDS             complement(9909..10742)
                     /locus_tag="VVR63_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001015777.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
     gene            complement(10732..12579)
                     /gene="uvrC"
                     /locus_tag="VVR63_001019"
     CDS             complement(10732..12579)
                     /gene="uvrC"
                     /locus_tag="VVR63_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HEU6129046.1"
                     /translation="MNNLIKSKLELLPTSPGCYIHKDKNGTIIYVGKAKNLRNRVRSY
                     FRGSHDTKTEALVSEIVDFEFIVTESNIEALLLEINLIKENKPKYNIMLKDDKSYPFI
                     KITNERYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
                     YYHIGQCMAHTICKKDEIYFKSMAQEVSDFLKGQDNKIIDELKGKMAAAAQTMEFERA
                     AEYRDLIQAIGTLRTKQRVMAKDLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNL
                     FPYFNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKALVDSKILKPQRGEKK
                     QLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGT
                     SPVSAMVVFVNGKPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREALTPPDLI
                     VIDGGQGQVNIAKQVIQEELGLDIPIAGLQKNDKHQTHELLFGDPLEVVDLSRNSQEF
                     FLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMRHFKSLTKIKEA
                     SVDEIVEVGVPRAVAEAVQTKLNPQETEILLQVAEERVDYQTEGNHNKP"
     gene            complement(12619..13320)
                     /locus_tag="VVR63_001020"
     CDS             complement(12619..13320)
                     /locus_tag="VVR63_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="matrixin family metalloprotease"
                     /protein_id="HEU6129047.1"
                     /translation="MRWLFRLIGAFFSFVWRLFWRLVWIVVLLCVLAFGLLWYLNGDF
                     QGALKQAERSVKIGQQSIDQWEKTGQLPKLSQTDSHQHSEGRWAQASARIYLDPQMDS
                     RFQEAYLEAIQNWNQTGAFNFELVTESSKADITATEMNDGGTPVAGEAESQTNLLTGQ
                     FLSVTVRLNHYYLSNPYYGYSYERLVHTAEHELGHAIGLDHTDEKSVMQPAGSFYGIQ
                     EEDVANLRKIYETSE"
     gene            complement(13399..14631)
                     /gene="murN"
                     /locus_tag="VVR63_001021"
     CDS             complement(13399..14631)
                     /gene="murN"
                     /locus_tag="VVR63_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurN"
                     /protein_id="HEU6129048.1"
                     /translation="MALTTLTKEEFQTYSDQVSSRSFMQSVQMGDLLEKRGARIVYLA
                     LKQEGEIQVAALVYSLPMLGGLHMELNSGPIYTQQDALPVFYAELKEYAKQNGVLELL
                     VKPYETYQTFDSQGNPIDAEKKSIIQGLTDLGYQFDGLTTGYPGGEPDWLYYKDLTEL
                     TEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSLEY
                     YEHFYDTFGEQAEFLIASLNFSDYMSKLQGEQSKLEENLDKLRLDLSKNPHSEKKQNQ
                     LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKF
                     YAPALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYH
                     PSPLKYKAIQLLKKIVGR"
     gene            complement(14636..15856)
                     /gene="murM"
                     /locus_tag="VVR63_001022"
     CDS             complement(14636..15856)
                     /gene="murM"
                     /locus_tag="VVR63_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurM"
                     /protein_id="HEU6129049.1"
                     /translation="MYRYQIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFG
                     VYREEKLLATASILIRTLPLGYKMFYIPRGPILDYGDKELLNFAIQSIKSYARSKRAV
                     FVTFDPSICLSQSLINQEKTEFPENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKI
                     YKENFEEDKLSKSTKQAIRTARNKGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEA
                     YYKKLLDNFKDKAYITLATLDVSKRSQELEEQLAKNRALEETFTESTRTSKVEAQKKE
                     KERLLEELTFLQEYIDVGQARVPLAATLSLEFGTTSVNIYAGMDDDFKRYNAPILTWY
                     ETARYAFERGMVWQNLGGVENSLNGGLYHFKEKFNPTIEEYLGEFTMPTHPLYPLLRL
                     ALDFRKTLRKKHRK"
     gene            complement(15968..16747)
                     /locus_tag="VVR63_001023"
     CDS             complement(15968..16747)
                     /locus_tag="VVR63_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HEU6129050.1"
                     /translation="MAVMKIEYYSQVLDMEWGVNVLYPDANRVEEPECEDIPVLYLLH
                     GMSGNHNSWLKRTNVERLLRGTNLIVVMPNTSNGWYTDTQYGFDYYMALAEELPQVLK
                     RFFPNMTSKREKTFIAGLSMGGYGCFKLALTTNRFSHAASFSGALSFQNFSPESQNLG
                     SPAYWRGVFGEIRDWTTSPYSLESLAKKSDKKTKLWAWCGEQDFLYEANNLAVKNLKK
                     LGFDVTYSHSAGTHEWYYWEKQLEVFLTTLPIDFKLEERLT"
     gene            complement(16816..18477)
                     /locus_tag="VVR63_001024"
     CDS             complement(16816..18477)
                     /locus_tag="VVR63_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEU6129051.1"
                     /translation="MSNISLTTLGGVRENGKNMYIAEIGESIFVLNVGLKYPENEQLG
                     VDVVIPNMDYLFENSDRIAGVFLTHGHADAIGALPYLLAEAKVPVFGSELTIELAKLF
                     VKGNDAVKKFNDFHVIDENTEIDFGGTVVSFFPTTYSVPESLGIVLKTSEGSIVYTGD
                     FKFDQTASESYATDFARLAEIGRDGVLALLSDSANADSNIQVASESEVRDEITQTIAD
                     WEGRIIVAAVSSNLSRIQQIFDAADKTGRRIVLTGFDIENIVRTAIRLKKLSLANEIL
                     LIKPKDMSRFEDHELIILETGRMGEPINGLRKMSIGRHRYVEIKDGDLVYIATAPSIA
                     KEAFVARVENMIYQAGGVVKLITQSLHVSGHGNVRDLQLMINLLQPKYLFPVQGEYRE
                     LDAHAKAAMAVGMLPERIFIPKKGTTMAYENGDFVPAGSVSAGDILIDGNAIGDVGNV
                     VLRDRKVLSEDGIFIVAITVNRREKKIVARARVHTRGFVYLKKSRDILRESSELINQT
                     VEEYLQGDDFDWADLKGKVRDNLTKYLFDQTKRRPAILPVVMEAK"
     gene            complement(18652..20874)
                     /gene="recJ"
                     /locus_tag="VVR63_001025"
     CDS             complement(18652..20874)
                     /gene="recJ"
                     /locus_tag="VVR63_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001832038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HEU6129052.1"
                     /translation="MITPTYEWQFALQVEDADFTKIAKKAGLGPEVARLLFERGIQDQ
                     ESLKKFLEPSLEDLHDAYLLHDMDKAVERIRQAIEERENILVYGDYDADGMTSASIVK
                     ESLEQLGAECRVYLPNRFTDGYGPNASVYKYFIEQEGISLIVTVDNGVAGHEAIALAQ
                     SMGVDVIVTDHHSMPETLPDAYAIVHPEHPDADYPFKYLAGCGVAFKLACALLEEVQV
                     ELLDLVAIGTIADMVSLTDENRILVQYGLEMLGHTQRIGLQEMLDMAGIAANEVTEET
                     VGFQIAPRLNALGRLDDPNPAIDLLTGFDDEEAHEIALMIHQKNEERKEIVQSIYEEA
                     KTMVDPEKKVQVLAKEGWNPGVLGIVAGRLLEELGQTVIVLNIEDGRAKGSARSVEAV
                     DIFEALDPHRDLFIAFGGHAGAAGMTLEVEQLSDLSQVLEDYVREKGADAGGKNKLNL
                     DEELDLEALSLETVKSFERLAPFGMDNQKPIFYIKNFQVESARTMGAGNAHLKLKISK
                     GEASFEVVAFGQGRWATEFSQTKNLELAVKLSVNQWNGQTALQLMMVDARVEGVQLFN
                     IRGKNAVLPEGVPVLDFPGELPNLAASEAVVVKNIPEDITQLKTIFQEQHFSAVYFKN
                     DIDKTYYLTGYGTRDQFAKLYKTIYQFPEFDIRYKLKDLAAYLNIQQILLVKMIQVFE
                     ELGFVTIKDGVMTVNKEAPKREIGESQIYQNLKQTVKDQEMMALGTVQEIYDFLMEKE
                     "
     gene            21151..21909
                     /locus_tag="VVR63_001026"
     CDS             21151..21909
                     /locus_tag="VVR63_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU6129053.1"
                     /translation="MALVEFKNVEKYYGDYHALRNINLRFEKGQVVVLLGPSGSGKST
                     LIRTINGLEAVDKGSLLVNGHQVAGASQKDLVPLRKEVGMVFQHFNLYPHKTVLENVT
                     LAPIKVLGIDKKEAEKTAKKYLEFVNMWDKKDSYPAMLSGGQKQRIAIARGLAMHPEL
                     LLFDEPTSALDPETIGDVLAVMQKLARDGMNMIIVTHEMGFAREVADRIIFMADGEVL
                     VDTTDVDNFFDNPSEPRAQQFLSKIINHESDKVK"
     gene            21949..22713
                     /locus_tag="VVR63_001027"
     CDS             21949..22713
                     /locus_tag="VVR63_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEU6129054.1"
                     /translation="MISLFGLAAAKPVQADTSIADIQKRGELVVGVKQDVPNFGYKDP
                     KTGTYSGIETDLAKMVADELKVKIRYVPVTAQTRGPLLDNEQVDMDIATFTITDERKK
                     LYNFTSPYYTDASGFLVNKSAKIKKIEDLNSKTIGVAQGSITQCLITELGKKKGLTFK
                     FVELGSYPELITSLHAHRIDAFSVDRSILSGYTSKRTELLDDSFKPSDYGIVTKKSNT
                     ELNDYLDNLVTKWSKDGSLQKLYDRYKLKPSSHTAD"
     gene            22726..23403
                     /locus_tag="VVR63_001028"
     CDS             22726..23403
                     /locus_tag="VVR63_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU6129055.1"
                     /translation="MTDLSSWTAYFQDFGQFFNGFLFTLALAIGFFILAMVLGIFFGA
                     MSTSKRPILRILAHIFVEFYQNTPLLVQFVIVFYGLPLISDHTIMIPIYWTAVLCVGL
                     YHGAYIAEVIRSGIQSIPSGQMEAALSQGFTYISAMRLITLPQAFRIILPPLTNQIVN
                     LIKNTSTVAIISGVDLMFVTKSWSALNGNYIPAFLGAALLYFALCFPVAQFGRKMEQA
                     NKKAYSL"
     gene            23413..24072
                     /locus_tag="VVR63_001029"
     CDS             23413..24072
                     /locus_tag="VVR63_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU6129056.1"
                     /translation="MESILEILTPDNLVFIFKGFGLTLYISLIAIILSTIIGTVLAVM
                     RNGKNPILRIISSIYIEFVHNVPNLLWIFTIFLVFKMKSTPAGITAFTLFTSAALAEI
                     IRGGLNAVDKGQYKAGMSQGFTSAQILYYIILPQASRKMLPAIISQFVTVIKDTSLLY
                     SVIALQELFGASQILMGRYFEPEQVFSLYILIALIYFSFNLAISSLSHMLAKRWQQAA
                     E"
     gene            24367..25557
                     /locus_tag="VVR63_001030"
     CDS             24367..25557
                     /locus_tag="VVR63_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="HEU6129057.1"
                     /translation="MKSVKGLLFIIASFILTLLTWMNTSPQFMIPGLALTSLSLTFIL
                     ATRLPLLESWFHGLEKVYTVHKFTAFLSIILLIFHNFSMGGLWGSRLAAQFGNLAIYI
                     FASIILVAYLGKYIQYEAWRWIHRLVYLAYILGLFHIYMIMGNRLLTFNLLSFLVGSY
                     ALLGLLAGFYIIFLYQKISFPYLGKITHLKRLNHDTREIQIHLCRPFNYQSGQFAFLK
                     IFQEGFESAPHPFSISGGHGQTLYFTVKNSGDHTNNIYDNLQAGSKVTLDRAYGHMII
                     EEGRENQVWIAGGIGITPFISYIREHPILDKQVHFYYSFRGDENAVYLDLLRNYAQKN
                     PNFELHLIDSTKDGYLNFEQKEVPEHATVYMCGPISMMKALAKQIKKQNPKTELIYEG
                     FKFK"
     gene            complement(25878..26759)
                     /locus_tag="VVR63_001031"
     CDS             complement(25878..26759)
                     /locus_tag="VVR63_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HEU6129058.1"
                     /translation="MAIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAP
                     VLIQTSMGAAKYMGGYKVARNLIANLVESMGITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGEEDGIIGKGELAPIEDAK
                     AMVETGIDFLAAGIGNIHGPYPVNWEGLDLDHLQKLTEALPGFPIVLHGGSGIPDEQI
                     QAAIKLGVAKVNVNTECQIAFANATRKFARDYEANEAEYDKKKLFDPRKFLADGVKAI
                     QASVEERIDVFGSEGKA"
     gene            complement(26900..28228)
                     /gene="vncS"
                     /locus_tag="VVR63_001032"
     CDS             complement(26900..28228)
                     /gene="vncS"
                     /locus_tag="VVR63_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase VncS"
                     /protein_id="HEU6129059.1"
                     /translation="MKRTGLFTKIFIYTFSIFSVLVICLHLAIYFLFPSTYLSHRQET
                     IGQKATAIAQSLEGKDRQSIEQVLDLYSQTSDIKGTVKGEMTEDKLEVKDSLPLDTDR
                     QTTSLFIEEREVKTQDGATMILQFLASMDLQKEAEQISLQFLPYTLLASFLISLLVAY
                     IYARTIVAPILEIKRVTRRMMDLDSQVRLRVDSKDEIGNLKEQINSLYQHLLTVIADL
                     HEKNEAILQLEKMKVEFLRGASHELKTPLASLKILIENMRENIGRYKDRDQYLGVALG
                     IVDELNHHVLQILSLSSVQELRDDRETIDLLQMTKNLVKDYALLAKERELQIDNSLTH
                     QQAYLNPSVMKLILSNLISNAIKHSVPGGLVRIGEREGELFIENSCSSEEQEKLAQSF
                     SDNASRKVKGSGMGLFVVKSLLEHEKLAYRFEMEENRLTFFIDFPKVVQD"
     gene            complement(28225..28881)
                     /gene="vncR"
                     /locus_tag="VVR63_001033"
     CDS             complement(28225..28881)
                     /gene="vncR"
                     /locus_tag="VVR63_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor VncR"
                     /protein_id="HEU6129060.1"
                     /translation="MKILIVEDEEMIREGVSDYLTDCGYETIEAADGQEALEQFSSYE
                     VALVLLDIQMPKLNGLEVLAEIRKTSQVPVLMLTAFQDEEYKMSAFASLADGYLEKPF
                     SLSLLKVRVDAIFKRYYDTGRIFSYKDTKVDFESYSASLAGQEVPINAKELEILDYLV
                     KNEGRALTRSQIIDAVWKATDEVPFDRVIDVYIKELRKKLDLDCILTVRNVGYKLERK
                     "
     gene            complement(28930..29013)
                     /gene="pep27"
                     /locus_tag="VVR63_001034"
     CDS             complement(28930..29013)
                     /gene="pep27"
                     /locus_tag="VVR63_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_198523890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative autolysis signal peptide Pep27"
                     /protein_id="HEU6129061.1"
                     /translation="MRKEFHNVLSSDQLLTDKRPARDYNRK"
     gene            complement(29193..30572)
                     /gene="vex3"
                     /locus_tag="VVR63_001035"
     CDS             complement(29193..30572)
                     /gene="vex3"
                     /locus_tag="VVR63_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit Vex3"
                     /protein_id="HEU6129062.1"
                     /translation="MLHNAFAYVTRKFFKSIVIFLIIFLMASLSLVGLSIKGATAKAS
                     QETFKNITNSFSMQINRRVNQGTPRGAGNIKGEDIKKITENKAIESYVKRINAIGDLT
                     GYDLIETPETKKNLTADRAKRFGSSLMITGVNDSSKEDKFVSGSYKLVEGEHLTNDDK
                     DKILLHKDLAAKHGWKVGDKVKLDSNIYDADNEKGAKETVEVTIKGLFDGHNKSAVTY
                     SQELYENTAITDIHTAAKLYGYTEDTAIYGDATFFVTADKNLDDVMKELNGISGINWK
                     SYTLVKSSSNYPALEQSISGMYKMANLLFWGSLSFSVLLLALLLSLWINARRKEVGIL
                     LSIGLKQASILGQFITESILIAIPALVSAYFLANYTARAIGNTVLANVTSGVAKQASK
                     AAQASNLGGGAEVDGFSKTLSSLDISIQTSDFIIIFVLALVLVVLVMALASSNLLRKQ
                     PKELLLDGE"
     gene            complement(30624..31271)
                     /gene="vex2"
                     /locus_tag="VVR63_001036"
     CDS             complement(30624..31271)
                     /gene="vex2"
                     /locus_tag="VVR63_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding subunit Vex2"
                     /protein_id="HEU6129063.1"
                     /translation="MTLLQLQDVTYRYKNTAEAVLYQIDYNFEPGKFYSIIGESGAGK
                     STLLSLLAGLDSPVEGSILFQGEDIRKKGYSYHRMHHISLVFQNYNLIDYLSPLENIR
                     LVNKKASKNTLLELGLDESQIKRNVLQLSGGQQQRVAIARSLVSEAPVILADEPTGNL
                     DPKTAGDIVELLKSLAQKTGKCVIVVTHSKEVAQASDITLELKDKKLTETRNTSK"
     gene            complement(31284..32561)
                     /locus_tag="VVR63_001037"
     CDS             complement(31284..32561)
                     /locus_tag="VVR63_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6129064.1"
                     /translation="MNPIQRSWAYVSRKRLRSFILFLILLVLLAGISACLTLMKSNKT
                     VESNLYKSLNTSFSIKKIENGQTFKLSDLASVSKIKGLENVSPELETVAKLKDKEAVT
                     GEQSVERDDLSAADNNLVSLTALEDSSKDVTFTSSAFNLKEGRHLQKGDSKKILIHEE
                     LAKKNGLSLHDKIGLDAGQSESGKGQTVEFEIIGIFSGKKQEKFTGLSSDFSENQVFT
                     DYESSQTLLGNSEAQVSAARFYVENPKEMDGLMKQVENLALENQGYQVEKENKAFEQI
                     KDSVATFQTFLTIFLYGMLIAGAGALILVLSLWLRERVYEVGILLALGKGKSSIFLQF
                     CLEVVLVSLGALLPAFVAGNGITTYLLQTLLASGDQASLQDTLAKASSLSTSILSFAE
                     SYVFLVLLSCLSVALCFLFLFRKSPKEILSSIS"
BASE COUNT         9238 a         7496 c         6078 g         9883 t
ORIGIN      
        1 cgacttctga gctactatag tagattgaaa ctagaatagt acacctctac ttctaaaaca
       61 ttgttagaaa tcgatttgac tgtcctgaac gattcgtcct attcttattt cattttatta
      121 taattgatag tggtcgcccc agccagatac cttatccgct atataggcct tattatcacg
      181 ttcctgttcg tagagccacg atttcgctat cccttcctct gacgattctt atttccagcg
      241 tcagacttgg gaatcgctat tgggttcacc ggtagtaggt gcccaccgag gacttacacc
      301 tcagatatac gacatgcccg tcgtacatca aaaaaagttg agacatagtg tcttcaactt
      361 ttttacatta ctttaactac tgattaaagt gagtttacgt caactttgat accaacacct
      421 tgagtagttg tgatagtcaa gtttgttacg taagttcctt tagctgtagc tggttttact
      481 ttttggattg tttcgttgaa agctttaaag ttttcaacca atttttcagc ttcaaatgat
      541 actttaccga tgattgcttg aacgttacct gcacggtcag cacggtaagt gattttacca
      601 cctttagact cttcaactgc tttagcaaca tccattgtta cagtaccagt tttagggttt
      661 ggcatcaagt tacgtggtcc aaggacacgt ccaagacgtc caacaagagc catcatatca
      721 ggtgtagcga taactacgtc gaagtccaac caaccgtcgt tgattttagc aacaaggtca
      781 tcttcaccaa caaagtctgc accagcagct tttgcttctt cagcttttgc accacgtgcg
      841 aaaacaagaa cacgtgaagt tttaccagta ccgtttggca ataccattgc tccacggatt
      901 tgttggtcag cttttttaac gtcgatgttc aagttgtaag caacttctac agttgcatca
      961 aattttgcaa agttagtttc ttttgcaagt gctacagctt cttctacact gtatgctttt
     1021 gtgctgtcga ttttctcaag agcagcacga agttgtttgc tttttttagc cattttctat
     1081 tctccttgta agtggttcaa tcgattttca tctcccacgt cacttctcga aatgatgaag
     1141 tcttgcgggt tttcagtcta ctatttttct cttcctacgg ccttaagctc ccttgctgta
     1201 tccaagtaca agcctcagtc acttgcctag tatgaaaagc aactaataga ctgctgtgag
     1261 attttctact gtgttattga ttagtcaaca acagtgaatc ccatagaacg agcagtacct
     1321 tcgatcatac gcattgcaga ctctacgttt gctgcgttca aatctggcat cttagtttct
     1381 gcaatttctt gtacttgtgc acgagtaact gtagcaactt tagttttatt aggtgtacct
     1441 gatccttttt caacacctgc agcttttttc aaaagaacag cagctggtgg tgttttcgta
     1501 acgaaagtaa atgatttatc ttcgtaaact gagataacaa ctggaatgat cataccagct
     1561 tggtcagctg tacgagcgtt gaactctttt gtgaatccca tgatgttgat accagcttga
     1621 ccaagagcag gtccaaccgg tggagctggt gtagctttac cagcagggat ttgcaatttt
     1681 acaagttttt cgactttttt agccattttt aaatcctcct ttgtggtttt ggcggtaatt
     1741 agagattttt acctcccaca agtatgcttt acacatacct ttccattata cactatttat
     1801 ctaaaaatgc aagagaaaac tttcattttt aatcgacata atcgccgcct tcaaagccat
     1861 agtactcttc caaactgaga ccacttgcag caatttcttt ggcttctttt ccaacgtagc
     1921 ggagatgcca ttcttctgcc atgtagccag tctccttttc cttgccttta agatagcgaa
     1981 caacaaagcc atagtcagcc gcatggtcca agagccactg ggctgccttt tcttcagtaa
     2041 ctaaatcccc atctgtccca atcaaatcaa aagcaagacc cgtctggtgt tcactgtaac
     2101 ctgggcgtgc tgagtagcga tctgctgctt ccttaccatc ttgattgaca tagtcttggt
     2161 agagcttagc ctgagtttca taactcctaa acccactgta ttggtcactg attggatagc
     2221 cctcagcctg catagctgcg attagtttga gcaactctgc cttggctgtt ggattttctc
     2281 ctggattgta atcttttgac aaaggataac gtttattagc taggataatc tcatcgtatt
     2341 tcccttggat actataatag ctccctttat tgctaacttc tgcctttttc tgactagaag
     2401 cttgagattt gctacctaca gttccttccg gttgactgct ttgctccgtt ttttgagtgt
     2461 tttcttcaac tttggttttt tcttgcgaac aagctgcaag ggtcaatgct agtaaaccag
     2521 ataaaatgac atatcttttt ttcatttctt tcttcctctc tcttaggcca aatacttctc
     2581 caattcatga gataagattt taatcatctc ttccagctct ggcgattgta cttggcaatc
     2641 ttctgccgcc atttcttccc agggcaccca ccagactggg ccacggccat tcaaaccgtg
     2701 actcttcata tcacctgctc ttcggggaaa aagatgccaa tgagcgtggg catcgccatt
     2761 tcctaggagt tcaatattca tcttttcagc ctcaaatgct ttggcgactg cttcttggac
     2821 taaactcatt tcctctaaaa agcgaagttt tacagaagtt tccatatgat ggagttctgt
     2881 gacatgatct tttgctaaaa ataaggtata gcccttaaag tattggtagt caccaataac
     2941 aacatagcct gtttctagtt cttttacaaa gtagggattt tgcccagctt taatgagttc
     3001 gattctctga cagattaagc acattctatg ataccgcctc gctcttaaga taagcatcaa
     3061 ccatacgctc agtcgctatt actgaatcga tgtgggtgcg ctcataagag tgactggact
     3121 caataccagc tccaagaagt gcatgcttga cctctgcacc tgctgacatc gctgctgaag
     3181 cgtccgatcc gtaaaatgga tagatgtcga gcttaaatgg aatatcttgc tctttagcca
     3241 aggcaaccaa gtgttgacgg aagtcatagt gataaggacc tgaagcatcc ttgacacaga
     3301 tagatactgt gtactcatct gtctgctggt catctcccat agctcccata tccacagcca
     3361 gatattctac tacctgagca ggaatgttag aattagcacc atgtcctact tcttcaaaaa
     3421 ctgaaaaagc aaaatgagtt gttactggca attcaatctt ctctttctta taaatacgaa
     3481 gcaggttgag caaaatcgct gcgctgacct tatcatccaa atgacgagac ttgataaaac
     3541 ctgtatcagt cacaacagtt cgtgtatcga agctgataaa atcaccgacc tcaatcccaa
     3601 gagcacgagt ttctttttca ttgcttactt ttacatccaa acgcacttcc atattgtcct
     3661 gcgtgcgttc tgcagttcct gcatccttgt agacatggca agaagtttgg tggatgagga
     3721 tggttcctga taccttttga cctgtgctag ccacatgaac ggtacagttt tcaccttcaa
     3781 tcatgttcca aggaaaacca ccgatacggt ccaatttaag acgaccatct ggtttgacag
     3841 cacgaacaat agcacccagc gtatccacat gggcagtcac atagcgatgt tgctcatcat
     3901 tttgaccttt gatggtcaca ttgacaccac ccttagctgt gcgaactggc tggtaaccaa
     3961 aaccttctag agtcttgact aaataattcg aaatttcacg agtgaagccc gttggcgatg
     4021 cgatggctgt cagttctttg atatattcta ctgtttgatt catttcttca cctctttcgc
     4081 tacctattat aacacattta tcatcggata aaaaaagaaa atcactcctg tagacttggc
     4141 tacaaaagtg atttaagtga ttattccatt tcaaaaacat cgctttcttg cttgtttggt
     4201 agaaccaatg agagcaagat tccaacaatg gctggcacca accatgggag agatgccttg
     4261 gcaaaaggaa gaacgctaac aagatttgca agaaactcaa ccttaaacga gcttcctagt
     4321 acgcttgcaa tggcaataac tgtaaccaca gcaattgtca actgcatacc tggttttgaa
     4381 agggcaacaa atttgttgac aatgacaatc ataacgatag caatcgtgat tgggtacaag
     4441 ataaccagta ctggaattga gtacttgata atcgcatcaa gacccaaatt ggcaatagca
     4501 aatccaatca aggtaaaggc tgtcgcataa accttgtagc tgatttgtgg gaagcgctca
     4561 ttaaagaact cagctgttga cacaatcaaa ccaacagtcg ttgtgaagca ggttacggta
     4621 accatagctg caaggaagag ttgagctgtt gagccaaaga tttcttgagt ggcttgtgac
     4681 aagatgtaaa cacctggtgt tccacccttc atcgcttcag ctggtactgg gaaatgattt
     4741 ccaagaaaac ctaaaccgat gtaaagagcg ctgaaggcaa gggcaacaac gataccaaca
     4801 acccaaatag ttgaaatgta ttctttctta cttgaaaatc caagttgttt caaggtttga
     4861 actgcgatta cgctaaaggc cactgaagca agggcgtcca aggtattgta accttctagg
     4921 aaacctgtac caaaggcaga agcttgataa gcagctgaag cagcttgagg acttgttcca
     4981 ccatatttga tagctcccag aacgaccaag ataacaatca aaattgcaaa gactggcgtt
     5041 aaaacacgtc caatgcggtc taagattttt gatggattaa gcgaaatcaa ataggctgcc
     5101 gcaaaataca gaaccgtaaa tacaatcaag ccaagtcctt tatttgcatc cgacaaaagg
     5161 gggctaatcc ctacttcgta agctgttgta gcagtacgtg gggtagcaaa gaatggaccg
     5221 attgacaagt aaagaactga gaggtaaaga gtcgcaaacc aaggcgctat cttcgttgaa
     5281 atctcgtaga tatatccttt aggatttagc gttccaataa taagggtcaa gacggcgata
     5341 ccaacgcctg aaaagacaaa acctgcgatg gcaggaagaa aatgttctcc agatagagca
     5401 cctagagaag gcggaaaaat caagttcccc gcaccaaaaa atattccaaa caggagcaaa
     5461 cctgttaggg tacctttttt agccataaaa atctccttca tatttataaa atactgacct
     5521 agtataccac gattaggagt ctgaaaaaag catcacgagg caaatattaa atgttttcaa
     5581 ttttcttaaa aataagaatt atctaaaaat aaaactctcc tacccagtcc acaccaagta
     5641 ggagaaatgc aaaattttaa agttcttcaa aggctaacat gccaccctgg acattgataa
     5701 cattataacc ttgttctaac aggaattggc aagcacgcgc cgatctcatt ccagatttgc
     5761 aaataatata atgcaagcga tctttgtcca attaatcata actatcagcc aattgactaa
     5821 gcggtaggtt gtgggcacat tctaaatgaa gagctgcaaa ctcatccact tctctcacat
     5881 ccactagaga aagctggtcg ttttggtaaa gctggtaaaa tgcgtcaaag gctatttctt
     5941 tcattctttt tcttctaata ctcttcgaaa atctcttcaa accacgtcag cgtcgcctta
     6001 ccgtgcgtat gttaccgact tcgtcagttt tatctgcaac ctcaaagctg tactttgagc
     6061 agcctacgac tagcttccta gtttgctctt tgattttcat tgactataaa atggttttaa
     6121 ttcttttttt caaatctggc actacttctg cctcaaacca aggatttttg gccatccaga
     6181 tttgatttcg tggtgatggg tgaactagcg gaaaataggc tggcagatag tctttatagt
     6241 gtttcaccct ctccgttacc ttcccactga ttttctcctg taaatagtag gcttgggcat
     6301 attgcccaat caagagggtt aactgaatat caggcaattc ctgtaagagc tgcggatgcc
     6361 atttttctgc aaaacctgta cgaggcggaa gatcacccga cttgccatgt cctggaaagt
     6421 agaaatccat aggcaaaaca gcaaaataac ctgaattgta aaaggtatct tcatccacac
     6481 ctagccagtc ccgcaagcgg tcaccacttt tatctttcca gtaaaggcct gcttcttgag
     6541 ttttaagtcc cggagcctga ccgatgatat tgatgcgagc agtttttggc gctgcaaaga
     6601 gaggctcaat gccacgctct gtatagctgg cattctgtga atccgccatg atagcctgtt
     6661 tgattctttc gatttgagac atctactttc cctccaaaaa gaagtccaag cataagatct
     6721 cagacttcta tcgttttatt tgatcaattc gtaaatagct tcggcataga ttgctgctgc
     6781 tcggaagaga tcgtccaagg cgataaattc attggcttgg tgcatggtat caattgagtc
     6841 tgggaacata gcaccatagg caactccgcg ctctaacaag cgaccaaagg ttccaccacc
     6901 gatgacttgt tcatgacctt taaagccagt ttgtttttca tagatattca acaaggtttg
     6961 cacaagtgga tcttccattg gcacatagtg aggcgtgtga ccgtgttcag acaggctaac
     7021 agaaacaact ggcaagtttt caaggattga cttgatttgt tctggacttg ttccttttgg
     7081 atagcggatg ttgagggcaa tggtattatc agcacttgtt tcatcgaagc ggaagacgcc
     7141 ggcattcata gaaagagcac ccatcttttc atccacatga gcaatcttaa gattttcacc
     7201 ctcatgatcg ttcaagagaa ttttacctgc gatgtcaagg tagtctttgg ctggaccagc
     7261 aaagccaaac tgactgagga agagggcaag gtaagttgcg ccattgacac ctgaagcagg
     7321 catagcaccg tgggctgatt taccaatgat cgtcaccttg tatttgccag cttcttcttg
     7381 gagttctcct ctaagtttgt gttctgcaac aaaggcatct agtttagctt gcaagtcagc
     7441 caagtcacct gaaacgactg ctgttgctga ttctggtacc atattttcac gtaaaccacc
     7501 tgtaaagctg tgaagacggg caacacctgt attttctcct gcaaagtgga ggtattccgt
     7561 gatatttcct ttttcaccat tgatgattgg aaattcagca tctggtgaga aaccgaaatc
     7621 tggtttggca agtcctacgt gctcaaagta gtagtccatg tctgcccagc ctgattcttc
     7681 gtctgttcca acgatgaagc gaactttctt agaagttgga agacccaatt ctttgatgat
     7741 tttcaaacca tagtaacaag ctgttgtagg acccttatcg tccgaagccc cgcgcgcata
     7801 aaggcgacca tctttgatag ttggtgtgta agggtctgtg tcccaaccgc taccagcagg
     7861 caccacatcc atatgggcaa agattccgag aacttcttct ccatcaccaa actcaaaatg
     7921 tcctgcatag ttatcaacat tcttagttgg gtagccatcg cggtctgcga tttcaaggaa
     7981 tttctccaag gcttttactg gaccaggccc aaatggatgc tgggcatcag ccttgctgtc
     8041 atcacgttct gaattgattt ccaaaaggct aaacaagtca gccaagaggt cttctttgcg
     8101 tttttctact tctgctgtaa aatcaattgc tgtcattttt tcttctttct atcttttctc
     8161 gatgatttca tctactggca agcggtagct tggttccaat ttttcgtctg tataacccac
     8221 tgtgatcaag agttctgggc ggaaacggtc ttcgatttcc aaaacttcat taacttttga
     8281 tttgtcaaaa ccaagaataa tgttagaacc aattccttgg tctgtcaatg caagaaccaa
     8341 gttcatggca accaaacctg cattgagagc taggtagtcg ctgacttgtt gttcattgta
     8401 gcgtgcaaat tcagctggca aatttttcat gaagtattga agttgttctt ctgagaaatt
     8461 gttagcacca ccaactcggg caatcttacg agcgcgtttg gcaaggtctg tatctgtaaa
     8521 tagggcaatg gttacaggtg ctgatgatac ctgctcaaag tttgaaccat aagccaactt
     8581 tgccagttca gcatttttct cacgaacaac tacaaatttc caaggctggc tgttgtgggc
     8641 gcttggcgcc aaggttgcaa tttcgatagc cgtacgcaca tcttttggat caacaggctt
     8701 atcagtgaaa tgcttggtcg catgacgttt tttatttaat tcaagaaatt tcataatcga
     8761 tttccttttc taattctact gcttccattc taccataatt tgaaagagct tgcagggatt
     8821 tttcatgatt aagtttttct atcacagaca taaaagatat atattggttt atcaggaaag
     8881 tttctgataa actagcaagt actttacatt tgaatggaga cagtatgaaa aaatttagcc
     8941 tattactagc tatcctacca tttttggttg cctgtgggaa tcaagctaca cccaaagaga
     9001 ctagcgctca aaagacaatc gtccttgcta cagctggcga cgtgccacca tttgactacg
     9061 aagataaagg caatctgaca ggcttcgata tcgaagttct aaaggcagta gatgaaaaac
     9121 tcagcgacta cgagattcaa tttcaaagaa ccgcctggga aagtatcttc ccaggacttg
     9181 attctggtca ctatcaggct gcggccaata atttgagtta cacaaaagag cgtgctgaaa
     9241 aataccttta ctcgcttccg atttccaaca atcccctcgt ccttgtcagc aacaagaaaa
     9301 atcctttgac ttctcttgac cagatcgctg gtaaaacaac acaagaggat accggaactt
     9361 ctaacgctca attcatcaat aactggaatc agaaacacac tgataatccc gctacaatta
     9421 atttttctgg tgaggatatt ggtaaacgaa tcctagacct tgctaacgga gagtttgatt
     9481 tcctagtttt tgacaaggta tccgttcaaa agattatcaa ggaccgtggt ttagacctct
     9541 cagtcgttga tttaccttct gcagatagcc ccagcaatta tatcattttc tcaagcgacc
     9601 aaaaagagtt taaagagcaa tttgataaag cgctcaaaga actctatcaa gacggaaccc
     9661 ttgaaaaact cagcaatacc tatctaggtg gttcttacct cccagatcaa tctcagttac
     9721 aataacactc ttcgaaaatc tcttcaaacc acgtcagctt tatctgcaac ctcaaagctg
     9781 tgctttgagc aacctacggc tagcttccta gtttgctctt tgattttcat attgagtata
     9841 agatatatta aaagcgatgg gatcagccaa tcgctttttt agtttgcatt ggttatttta
     9901 ggaaactctt acaaaaaatc aaaaaaattc ttcacatcct ctacatacct atgcttttct
     9961 attaagcttg ctaatagttc cagattgtgc ctctgatagt tatcttcacg acgtagttct
    10021 tcatacattt cgataaaggg aaaacccttg gatttggcaa attctaactc agcctcgtaa
    10081 tcataagcga ctttacgaaa taggatattt accaattccc catcttcaac ctctatcacg
    10141 gcatactggg cacggtgatt ttttaacgcc tcccaattaa aatagggcat gccaatcgac
    10201 cctggattga tgatttgttg cccttgacta ccataacgaa gcaactactt gtgaacatga
    10261 ccataaactg ccacgtccgt ttccgcatct agcagttggt caaatttctc tgtatcattc
    10321 tcaactagca agtcaccacc atagtttttg tcaggtaaat tatgagagat agaaaagcgc
    10381 aatccgtcaa tttctttctt ttccagcaaa ggcaagcttc gtagccagac aatcgttgca
    10441 ggatccattc gctccatcaa atactgtgtc atacgcaaga gctgaacttc ctgtgggtct
    10501 tctaagccat attgcccatc taaagcctca aggacacaat catcccaatt gcctcgaaca
    10561 cttgccgtga taggaagttc ctttaacaga gcgaccaagt catttgcacc tggaccaggg
    10621 aggaaaatgt ctcccatgag ccaatattca ctggctcctt gagttttagc atctgcaatc
    10681 actgcttcta gcgccgtcgc attgccatga acatctgata aaattgcgat tttatggttt
    10741 attgtggttt ccttccgttt ggtaatctac tctttcttcc gccacttgaa gcaagatttc
    10801 tgtttcctgc gggttcaact tggtttgcac agcctctgct actgctcttg gtactccaac
    10861 ttcgacaatc tcatccacac tggcttcctt gattttggtc agagacttga agtgcctcat
    10921 gagattttgc ttgcgtttag gtcccagacc atcaatccca tccaattgag atgagaaaga
    10981 atttttggag cgcagttggc ggtggaaggt aatggcaaag cggtggacct catcttgaat
    11041 gcgttggagg aggaaaaatt cctgagaatt gcgagacaag tccaccactt ccagcggatc
    11101 tccaaagagc aattcatggg tttggtgctt atcattcttt tgcagacctg caattggaat
    11161 atccaagccc agttcttctt ggatgacttg cttagcaata ttgacttgac cttgcccccc
    11221 atcaatcaca atcaaatctg gaggagtcaa agcctcacgc tgtactcgac catagcgtct
    11281 gcgaatgacc tctcgcatac tggcatagtc gtctggcccg actacggtct tgattttata
    11341 cttacggtaa tccttcttac taggcttgcc gttgacaaag accaccatgg ctgaaacagg
    11401 actagttccc atgatgttgg agttatcgaa ggactcgatg cgaactgggg ttgggatttg
    11461 aagcaagcgt cctagatttt caatagctcc ttgggtcttc tcgacagatt tctctagcag
    11521 gttgaacttc tgctctaggc taacacgggc attttttata gctaaattga ccagctgctt
    11581 tttctctcca cgttgaggct taagaatctt ggaatccacc aaggccttga cagcctcttc
    11641 gtcaatatct tgcggaatca gtacctcatt gggaactaga tgggattttt cttgatagaa
    11701 ttgtcctaca taggtcaaaa aatcctcatc tggatcattg aagtagggga agagattgac
    11761 atcgcgctcg atgagcttac cctgacggac aaagaaaacc tgcacacaca tccagccctt
    11821 atccacatag tagccaaaga catcgcgatt ttggagatcc ttagccatga cccgttgctt
    11881 ggttcgaagc gttccaatag cctgaatcag gtcacggtat tccgccgcac gttcaaactc
    11941 catagtctgg gctgccgctg ccattttgcc ctttagctca tcaatgattt tgttatcctg
    12001 ccctttcaga aaatcagaaa cctcctgggc catagacttg aaataaatct catccttctt
    12061 acagatggtg tgggccatgc attgaccgat atggtaataa aaacagacct tagagggcgg
    12121 gttggtacac ttacgaaaag ggaatatccg atccagcaac cgcttgattt cattggctgc
    12181 ccccacatcg ggatagggtc caaaataaag acctccgtcc tttttgacct gacgagtgat
    12241 aatcaagcgt ggatagcgct cattggtgat tttgatgaaa ggataggact tgtcatcctt
    12301 gagcatgata ttgtacttgg gcttgttttc cttgatcagg ttgatttcta ggagaagtgc
    12361 ctcaatatta gactccgtaa caataaattc aaaatccaca atttcagaca ccagagcctc
    12421 tgtcttggta tcatgacttc cacgaaaata ggaccgtact cgattacgca gatttttagc
    12481 ctttcctaca tagataatgg tgccattttt atccttatga atgtagcaac cagggctggt
    12541 cggcaagagc tctagttttg atttaatcaa gttgttcata gttccattat agcaaaaaaa
    12601 gtagggaaag atagtaccct actcactagt ctcatatatt tttcggaggt ttgcaacatc
    12661 ctcttcctgg ataccataaa aggaacctgc tggttgcatg acagacttct catctgtatg
    12721 gtccaagcca atcgcatgac ctaactcatg ttctgccgta tggacaaggc gttcatagga
    12781 gtagccatag tatggattgg acaaataata atgattcaac cgcaccgtta cggacaagaa
    12841 ttgccctgtt aagagattag tttgactttc cgcctctcct gccacaggag tgcctccgtc
    12901 gttcatctcc gtagccgtaa tatccgcctt actagactca gtcacgagtt caaagttaaa
    12961 agcaccagtt tgattccagt tctggattgc ttctaaataa gcctcttgaa agcgtgaatc
    13021 catctgcgga tccaggtaaa tacgagcaga ggcctgtgcc caccttcctt cagaatgctg
    13081 gtgactatct gtctggctta acttaggcag ttgccctgtt ttctcccatt ggtcaatact
    13141 ttgttgacca atttttactg accgttctgc ttgctttagc gctccttgaa aatctccgtt
    13201 cagataccag agaagtccga aagcaagcac acataagagc acaactatcc aaaccagacg
    13261 ccaaaacaaa cgccacacaa aagaaaagaa agcccctatc aaacgaaaaa gccagcgcat
    13321 gtctctccac ctttctagca aataagaatt attttactaa aagaagctaa aagaaatcta
    13381 aatactgact ttttcatctt aacgtcctac tatttttttg agtaactgga tagctttgta
    13441 ttttaaagga gatggatggt aacggaaagt acctgctttg cgtacaatat agccattaaa
    13501 attctgttta aaacgcaaaa caccatcact tccatcaaaa atcccttgaa tgcctaggaa
    13561 gttgtattta ggtattccac gttttatgct ttccaacata acatattttt gaagcagggc
    13621 aggggcatag aacttattaa actcagtgta ggaaccacta aagagataag tcgtttcctg
    13681 aggcatataa acaaataaac tcccagctaa aacaatatct tcttctccat atttttcaat
    13741 caagtctcgc gcttctgctt ttcgaacttc aaacgtttca aattgactag aatattctct
    13801 cagttgattt tgttttttct cagaatgagg atttttactc aaatcaagtc gcaacttgtc
    13861 caagttttct tctagtttac tttgttcacc ttgcaatttg ctcatatagt ccgaaaaatt
    13921 taagcttgct atgagaaact ccgcttgttc tccaaaagta tcataaaaat gctcataata
    13981 ttctaaactt ttatcactat attctctacg ttcagaggtt tcttttgtta tattcttaaa
    14041 aatcgatagt tcttcacgtt ttaacttttt caaccgaatg ccaaaggttt cagccttttt
    14101 caccaagggt ttaccctttt tgctaaaact tttaagcaaa ctcttttcag ttaattcagt
    14161 taaatcttta tagtataacc aatctggttc tccacctggg taacctgttg ttaagccatc
    14221 aaattgataa cctaaatcag tcaaaccttg aataatactt tttttctcag catctattgg
    14281 attaccttgg ctatcaaaag tttgataagt ttcataaggt tttacaagca actctaatac
    14341 accattttgc ttggcatatt cttttaactc tgcataaaaa actggaagag catcttgttg
    14401 ggtataaatt ggccccgaat tgagttccat atgcagacca cccagcatgg gcaagctata
    14461 aaccagagct gcaacttgaa tttctccttc ttgtttcaaa gcaagataaa caattcgagc
    14521 ccctcttttt tctagcaaat cccccatctg gacagattgc ataaaggaac gagaagaaac
    14581 ctgatcagaa taagtctgaa actcttcttt cgtgagtgtt gttagtgcca tatacttact
    14641 ttctatgttt ttttcttaat gttttacgga aatcaagagc aagtcttaac agaggataga
    14701 gaggatgagt gggcattgta aattcaccca agtattcttc aatcgttgga ttaaattttt
    14761 ccttaaaatg ataaagtcca ccattgagag agttttcaac accacctaaa ttttgccaga
    14821 ccatacctcg ctcaaaggca tagcgagccg tttcatacca tgttaaaatt ggtgcattgt
    14881 aacgtttaaa atcatcatcc ataccagcat atatattaac agaggtagta ccaaattcca
    14941 aactcaaagt agccgctaaa ggaactctcg cttgacctac atctatatat tcctgcaaga
    15001 aggtcaattc ctctaacaaa cgttcttttt ccttcttctg cgcttctact tttgaagttc
    15061 gagtcgactc agtaaacgtc tcttccaagg ctctattttt cgctaactgt tcttctaatt
    15121 cttgcgaacg tttagaaaca tccaaggtgg ccaaggtgat ataggccttg tccttaaaat
    15181 tatctaacaa ttttttataa taggcttcat tcctcaaatg aatctctttt cgcttctcag
    15241 tttttttcat caactccgaa aatgaatcta atagttccag tccaccatat tgaatctcaa
    15301 gccctttgtt tcgtgctgtt cgaatagcct gttttgttga cttggaaagt ttatcttctt
    15361 caaaattttc cttgtatatt ttcgcctgaa tacgaggttg aatggtgtct cccatttcct
    15421 ccgtttttcc tgaccacctt actcccattt gttgcaaact atcaataata gccagatttt
    15481 caggaaattc tgtcttttcc tgattgatta aactttgaga taggcaaata cttgggtcaa
    15541 aagtcacaaa aaccgctctc ttactgcgag cataggactt aatagactga atggcaaaat
    15601 tcaagagttc tttatcccca taatccaata taggtcctct tgggatgtaa aacattttat
    15661 agcctagcgg aagagttcta atcaaaatac tagctgtcgc cagtaatttt tcttccctgt
    15721 aaacaccaaa cttctcatgt tgccaattag acttaacttc ctcccaagca ctactttgta
    15781 atacattggc taattcatgt tctttgacaa actgatcata ttctaatgtg ggaatgccaa
    15841 tttgataacg gtacatttcc tactctcttt cctccagtat tttattacta ttctactact
    15901 ttcttttgaa aagtctagtg aaaacatatt ttattttagt tctactcccc ctatgctgaa
    15961 gttcaaacta agtcagtctc tcttctaatt tgaaatcaat tggtagggtt gttaaaaaaa
    16021 cttccaattg tttttcccag tagtaccact cgtgagttcc agcactatgg ctataggtca
    16081 catcaaaacc tagttttttg agatttttca ctgcgagatt attggcttcg tacaagaaat
    16141 cctgttcgcc acaccacgcc caaagtttgg tctttttatc cgatttttta gccagacttt
    16201 caagagaata gggactagtt gtccagtctc taatctctcc aaaaacacct ctccagtagg
    16261 ctggacttcc cagattttga ctttcaggag aaaagttttg aaagctgagg gcacctgaaa
    16321 aactagctgc atgagaaaaa cgatttgtcg taagagccag tttgaagcag ccgtagcctc
    16381 ccatagaaag accagcgata aaggtctttt cacgcttgct agtcatatta gggaagaagc
    16441 gtttcagaac ctgtggcaat tcctctgcta gagccatgta gtagtcaaaa ccatactggg
    16501 tatcggtgta ccaaccattg ctggtattgg gcataacaac gatgagatta gttcctcgaa
    16561 gcaagcgttc tacattggtc cgcttaagcc aactattatg atttccagac atcccgtgca
    16621 aaaggtacaa gacgggaata tcttcacact ctggttcttc cactcgattg gcatcagggt
    16681 agaggacatt caccccccac tccatatcca atacttgtga gtaatactcg attttcatta
    16741 ctgccatgat tttctccttc tatttttcta taagaaaaag ccgaaactcg actttctctc
    16801 tgtttatttc aacgattatt ttgcttccat gactactggt aaaatagctg gacgacgctt
    16861 ggtttggtca aagagatact tggtcaaatt atctcgaacc ttccctttaa gatctgccca
    16921 gtcaaagtca tctccttgaa gatactcttc taccgtttgg ttaatcaatt ctgaactttc
    16981 acggagaata tcgcgactct tcttgagata aacaaatccg cgcgtatgaa cacgagccct
    17041 agccacaatt ttcttctcac gacggttgac tgtaatagcc acgatgaaaa ttccatcctc
    17101 tgacaagacc ttacggtcac gaagaacaac atttccaaca tcaccaatgg cattcccatc
    17161 aatcaagata tctcctgctg aaaccgatcc agctggaaca aagtctccat tctcgtaagc
    17221 catggtcgtc ccctttttag gaatgaagat gcgttctggc aacatcccaa ctgccatggc
    17281 agccttagcg tgagcatcca actcacgata ctccccttgg acagggaaga ggtacttagg
    17341 ttgcaaaaga ttgatcatca gctgcaaatc acgcacattt ccgtgccctg atacatgtaa
    17401 actttgggta atcaatttga caaccccacc tgcctgataa atcatatttt ccacacgcgc
    17461 aacaaaggct tctttagcaa tagacggagc cgtagcaata tagaccaggt ccccatcctt
    17521 gatttctaca taacgatggc gaccaatcga catcttacga agtccattga taggttcacc
    17581 catacgacct gtctcaagaa taatcaactc atggtcttca aagcgagaca tatctttagg
    17641 cttaatcaag agaatttcgt tggctaaaga caacttctta agacgaatcg ctgtgcggac
    17701 gatattttca atatcaaatc ctgtcaagac gatacgtcga cctgttttat ccgcagcgtc
    17761 aaaaatctgc tgaatacgag aaagattact ggaaacagct gcaacgatga tacgaccttc
    17821 ccagtcagca atagtttggg taatttcatc cctaacttca ctttcactag ccacctgaat
    17881 attgctgtct gcattggccg aatcactgag gagagccagg acgccgtcac gaccaatctc
    17941 tgccaaacga gcaaaatcag ttgcataaga ttcactagcc gtttggtcaa atttgaagtc
    18001 acctgtataa acgatgcttc cttccgatgt cttcaagaca attcccagac tctctggaac
    18061 ggagtaagtc gtagggaaga aggaaaccac tgtcccacca aaatcaatct ccgtattctc
    18121 atcaatgaca tggaaatcat taaatttctt aacggcatca tttcctttga caaagagctt
    18181 tgccaactca atggtcaact cagacccaaa tacaggaact ttagcctctg ccaagagata
    18241 aggtagagca ccaatggcat ccgcatgccc gtgggtcaag aaaaccccag caatacggtc
    18301 gctattttca aaaaggtaat ccatgtttgg aatcaccaca tcgaccccta attgttcatt
    18361 ttcaggatat tttaacccta cattcaaaac aaaaatggac tctccaattt cagcaatgta
    18421 catatttttt ccattctcac gcacaccacc aagtgttgtt aaactgatat tactcatttt
    18481 tcctccaaaa tcttagttta tcttgattat agggcaactc taccctctta ttctaaaagt
    18541 tctgatactt tcagccgaat cttttcctac cattatacca tttttttgat gattttcaaa
    18601 atgaaggtct gttttcaaaa aagagttgat ttcccaactc tttcctaact tctactcttt
    18661 ttccatcaaa aaatcataaa tttcttgcac cgtacccagc gccatcattt cttggtcttt
    18721 aacggtttgt ttgagatttt ggtaaatttg actttctcct atctcccgct ttggcgcctc
    18781 tttattgact gtcatcacac catcttttat cgtcacaaag cctagttctt caaatacttg
    18841 aatcatcttg accagcaaga tttgttgaat attaagatat gcagccaaat ctttcagctt
    18901 gtagcgaata tcaaactctg ggaactggta aatagtcttg tacaatttag caaactgatc
    18961 tctagtccca taacctgtca gataataggt cttgtcaata tcatttttga aatagacagc
    19021 agagaaatgc tgttcctgaa aaatggtctt cagctgagta atatcctctg gaatgttttt
    19081 tacgacaaca gcttcactag ccgcaagatt tggcagttct ccaggaaaat ccaagactgg
    19141 aacaccttct ggcaagactg cattttttcc acgaatgtta aaaagttgaa caccttccac
    19201 tcgcgcatcc accatcatca actggagggc agtttggcca ttccattggt tgacagacaa
    19261 tttaaccgct aactctagat tcttggtttg agaaaactct gtcgcccatc tgccttgacc
    19321 aaaggctacc acttcaaaac tcgcctcacc cttggaaatt ttcagcttta gatgggcatt
    19381 acctgccccc atagtacgag cactttcgac ctgaaaattc ttgatataaa aaataggttt
    19441 ctgattatcc attccaaaag gagctaaacg ttcaaaactt ttgaccgttt ccaagctaag
    19501 tgcctccaaa tccaactctt catctaggtt taacttattc ttgccaccag catctgcacc
    19561 tttttcacga acataatctt ccaaaacctg agataaatct gagagttgct caacttccag
    19621 cgtcataccc gctgcacctg catgacctcc aaaggcgatg aagaggtctc gatggggatc
    19681 cagagcttca aaaatatcga ccgcttccac actacgagca ctgcccttgg cacgaccgtc
    19741 ttctatatta agaacaatga ctgtctgtcc caattcttcc aataaacgac cagccacgat
    19801 tcctagaacc ccaggattcc agccttcctt ggccaagacc tgaaccttct tctcaggatc
    19861 caccatggtc ttggcttctt catagataga ctgaacgatt tccttgcgct cttcgttttt
    19921 ctggtgaatc ataagggcaa tctcatgcgc ttcctcatca tcaaatccag tcaacaaatc
    19981 aatggcagga ttgggatcat ccaagcggcc caaggcattc aaacgaggag caatctggaa
    20041 accaaccgtt tcttctgtta cttcgttggc agcaatccca gccatgtcca gcatttcttg
    20101 cagaccaatg cgctgggtat gacccaacat ttccagacca tattgaacta agatacgatt
    20161 ttcatccgtc agactcacca tatctgcaat agttccaata gcgaccaaat caagcaattc
    20221 cacttgcact tcttctaaca gggcacaagc caacttgaaa gcaactccac aaccagccaa
    20281 atatttaaaa ggataatccg catctggatg ttcaggatgg acaatagcat aagcatctgg
    20341 cagggtttca ggcatggaat gatggtctgt cacaatgaca tctactccca tagactgagc
    20401 caatgcaata gcctcatgac cagcaacccc attgtccacc gtcacaatca aggaaatccc
    20461 ttcttgctcg ataaagtatt tataaacact agcattaggg ccatagccat cggtaaaacg
    20521 atttggcagg taaactcggc actcagcacc aagttgttcc aaactttcct tcacaataga
    20581 agccgaagtc atgccatccg catcgtagtc tccataaacg agaatatttt ccctttcttc
    20641 aatagcctga cgaatccgct ccactgcctt gtccatatca tggagcagat aagcatcatg
    20701 taagtcctcc aaggaaggtt ctaaaaactt cttcagactt tcttggtcct gaatccctct
    20761 ctcaaacaat aaccgagcca cctcaggacc cagtccagcc ttcttggcta tctttgtaaa
    20821 atccgcatct tctacctgca gggcaaactg ccattcataa gtaggtgtta tcaaaaagac
    20881 atccactctt tctaagaatt ctattgcttc attataacat gatttagacg ttttctctat
    20941 ccagattgct tttttataac attttatagt atattgaaac tagaatagta cacctctact
    21001 tctaaaatat tgttagaaat cgatttgact gtcccgatcg atttttcctg ttcttatttc
    21061 actatagtga attttttcag atacgatttg acaagaacat tcttttattg cagaatcgtg
    21121 ttataaaatc taacataaag gagttctctc atggctttag tagaatttaa aaacgtcgaa
    21181 aaatattacg gagactacca cgcactccgc aacatcaatc tccgttttga aaaaggacaa
    21241 gttgttgtcc tgcttggacc ttctggctct gggaagtcca ctcttatccg tacgatcaat
    21301 ggtttagagg ctgttgacaa aggaagtctc ctagtcaatg ggcaccaagt tgctggtgcc
    21361 agccagaaag atttggtacc tcttcgcaag gaagtcggca tggtttttca acattttaac
    21421 ctttatccac acaaaacagt gttagaaaac gtgacacttg cacctattaa agttctagga
    21481 attgataaaa aagaagctga aaaaaccgcc aaaaaatatc tggaatttgt aaatatgtgg
    21541 gacaagaaag attcctatcc cgccatgcta tctggtggac aaaaacagcg gatcgccatc
    21601 gctcgtggtc ttgctatgca tccggaactc ctcctctttg atgaaccaac atctgctctt
    21661 gatcctgaga ctatcggaga tgttctagca gttatgcaga aactggcgcg tgatgggatg
    21721 aacatgatca tcgttaccca cgaaatgggc tttgctcgag aggttgcgga ccgcattatc
    21781 tttatggccg acggagaagt tttagtagat acgacagatg tcgataactt ttttgacaat
    21841 ccaagcgaac ctcgtgccca acaattcctc agcaaaatta tcaaccacga aagtgacaaa
    21901 gtcaaataag gaggcgccta tgaaaaaaaa ttctttttat cagcattatt gattagcctt
    21961 ttcggccttg ctgctgccaa accagtccag gctgatacaa gtatcgcaga cattcaaaaa
    22021 agaggcgaac tggttgtcgg tgtcaaacaa gacgttccca attttggtta caaagatccc
    22081 aagaccggta cttattctgg tatcgaaacc gacttggcca agatggtagc tgatgaactc
    22141 aaggtcaaga ttcgctatgt gccggttaca gcacaaaccc gcggccccct tctagacaat
    22201 gaacaggtcg atatggatat cgcgaccttt accatcacgg acgaacgcaa aaaactctac
    22261 aactttacca gtccctacta cacagacgct tctggatttt tggtcaataa atctgccaaa
    22321 atcaaaaaga ttgaggacct aaacagcaaa accatcggag tcgcccaagg ctccatcacc
    22381 caatgcctga ttactgaact gggcaaaaag aaaggtctaa cctttaaatt tgtcgaactt
    22441 ggttcctacc cagaattgat tacttccctt cacgctcatc gtatcgatgc cttttccgtt
    22501 gaccgctcta ttctgtctgg ctacactagt aaacgcacag aactactaga tgatagtttc
    22561 aagccatctg actacggtat tgttaccaag aaatcaaata cagagctcaa cgactatctt
    22621 gataacttgg ttactaaatg gagcaaggat ggtagtttgc agaaacttta tgaccgttac
    22681 aagctcaaac catctagcca tactgcagat taaggaggac accccatgac agatttatca
    22741 tcttggacag cctattttca ggattttgga caatttttca atggtttcct ctttactctt
    22801 gccctagcga ttggattctt tatcctcgcc atggtcttag gaatcttctt tggtgccatg
    22861 tcaaccagta aacgtccaat tttacgcatt ttagctcaca tctttgtgga attttaccaa
    22921 aacactcccc tcttggtgca gtttgttatt gttttttatg gcctacctct tatcagtgac
    22981 catactatca tgattccaat ttattggaca gctgttctct gcgtgggact ctatcacggc
    23041 gcttatatcg ctgaggttat tcgttcaggg attcagtcta ttcctagtgg tcagatggag
    23101 gccgccttgt cgcaaggttt tacctatatc agtgccatgc gcttgattac cttgcctcag
    23161 gccttccgca tcattctccc tccattgacc aaccaaattg ttaacctcat caagaacaca
    23221 tctactgtag ctatcatctc tggagtagac ttgatgtttg tgactaagtc ttggtcggct
    23281 ctcaacggaa actatatccc agccttttta ggtgctgctc ttctctactt tgccctatgc
    23341 ttccctgttg cccagtttgg tcgcaagatg gagcaagcca ataaaaaagc ctattcactt
    23401 taggaggtta ctatggaatc tattttagaa attttaaccc cagataacct agtctttatc
    23461 tttaaaggat ttggcttgac cctctatatt tctctgattg ccatcatcct ctctactatc
    23521 atcggtaccg tgcttgccgt catgcgaaat ggaaaaaatc ctatcttacg cattatttcc
    23581 agtatttata tcgagtttgt gcacaacgtt cccaaccttc tctggatttt tactatcttt
    23641 ttggtgttca aaatgaagtc cacaccagca ggtattacag cctttactct ctttacatca
    23701 gcagccttgg ctgagattat tcgaggcggt ctcaatgccg tagacaaggg acaatacaaa
    23761 gcaggaatgt cacaaggctt cacctcagcc caaatcctct actacatcat tctcccacaa
    23821 gccagccgca aaatgctacc agccatcatt tctcagtttg ttaccgtgat taaggatacc
    23881 agtctcctct actctgttat cgccctacaa gaactctttg gagccagcca aattctcatg
    23941 ggccgttatt tcgaaccaga gcaggtcttc agtctttaca tcctgattgc cctcatctac
    24001 ttcagcttta acctagcaat ttctagcctg tctcatatgc tagccaaacg ttggcaacaa
    24061 gctgcagaat aatactcttc gaaaatctct tcaaaccacg tcagcttcac cttgccgtat
    24121 atatgttact gacttcgtca gttctatcca caacctcaaa acggtgtttt gagcagcctg
    24181 cggctagctt cctagtttgc tctttgattt tcattgagta taaacagcca ctctccagtt
    24241 caattggaga gttttttgat gagagtagat atttatagac ctcaatttga caccatacat
    24301 tttctatgat aaaatgtaac aaattcattt acaacaaatc gaaatctaaa tgaaatggaa
    24361 ttttctatga aatcagtcaa aggactactc tttatcatag ctagttttat cttgactctt
    24421 ttgacttgga tgaacacttc tccccaattc atgattccag gactagcttt aacaagccta
    24481 tctctgactt ttatcctagc cactcgtctc ccactactag aaagctggtt tcacggtttg
    24541 gagaaggtct acaccgtcca caaattcaca gcctttctct ccatcatcct actaatcttt
    24601 cataacttta gtatgggcgg tttgtggggc tctcgcttag ctgctcagtt tggcaatctt
    24661 gccatctata tctttgccag catcatcctt gtcgcctatt taggcaaata catccaatac
    24721 gaagcttggc gatggattca ccgcttggtt tacctagcct atattttagg actctttcac
    24781 atctacatga taatgggcaa tcgtctcctt acatttaatc ttctaagttt tcttgttggt
    24841 agctatgccc ttttaggctt actagctggt ttttatatca tttttctata tcaaaagatt
    24901 tccttcccct atctagggaa aattacccat ctcaaacgct taaatcacga tactagagaa
    24961 attcaaatcc atctttgcag acctttcaac tatcaatcag gacaatttgc ctttctaaag
    25021 attttccaag aaggctttga aagtgctccg catccctttt ctatctcagg aggtcatggt
    25081 caaactcttt actttactgt taaaaattca ggcgaccata ccaataatat ctatgataat
    25141 cttcaagccg gcagcaaagt aaccctagac agagcttacg gacacatgat catagaagaa
    25201 ggacgagaaa atcaggtttg gattgctgga ggtattggga tcaccccctt catctcttac
    25261 atccgtgaac atcctatttt agataaacag gttcacttct actatagctt ccgtggagat
    25321 gaaaatgcag tctacctaga tttactccgt aactatgctc agaaaaatcc taattttgaa
    25381 ctccatctaa tcgacagtac gaaagacggc tatcttaatt ttgaacaaaa agaagtgccc
    25441 gaacatgcaa ccgtctatat gtgtggtcct atttctatga tgaaggcact tgccaaacag
    25501 attaagaaac aaaatccaaa aacagagctt atttacgaag gattcaagtt caaataagta
    25561 atcatactct cctggaattt cccaggagag ttttttatag ccaaatgaaa taagacagga
    25621 acgatggaat tttggcattc aaatcaattg ataagaatgt tttatagtgg agtgaaatag
    25681 gatacgaaca aattgattag gaaaatcaaa tgaatttata gaaatctttt agcagttatg
    25741 ttatcctatt ctagtttcaa aacgctatag aagcagcatt gtgctagtct agattcagtt
    25801 tactatacta aaacgagtag cttgaaatca aaaaacccac cctcacaggc aggttttatc
    25861 tgtattattc agctagatta tgctttacct tctgaaccga atacgtcgat acgttcttca
    25921 accgatgctt ggatagcttt tacaccgtca gccaagaatt tacgtgggtc gaagagtttt
    25981 ttcttgtcgt attctgcttc gtttgcttcg tagtcacgag caaatttacg agttgcgtta
    26041 gcgaatgcga tttggcattc tgtgttaacg ttaactttgg caacaccaag tttgatagct
    26101 gcttggattt gctcatcagg aatacctgat ccaccgtgca atacgattgg gaatcctgga
    26161 agagcttctg tcaatttttg caagtggtca aggtcaagac cttcccagtt tactgggtaa
    26221 gggccgtgga tgttaccgat accagctgcc aagaagtcga taccagtttc aaccattgct
    26281 ttagcgtctt cgattggagc caattcacct ttaccgatga ttccgtcttc ttcaccaccg
    26341 atagtaccaa cttcagcttc tactgagata cctttagcgt gtgctttttc aacaacttct
    26401 ttagccaatt taaggttttc ttcaactgga aggtgtgaac cgtcaaacat gattgaagta
    26461 taaccaactt cgatacactc aagtgcatct tcgtagtgac cgtggtcaag gtggatagct
    26521 actggtacag tgatacccat tgattcaaca aggttagcga tcaagttgcg agcaactttg
    26581 taaccaccca tgtatttagc agcacccatt gaagtttgga tcaaaactgg agctttttta
    26641 gcttctgctg cgcgcaagat agcttgagtc cactcaaggt tgtttgtgtt aaatccacca
    26701 actgcataac cgttgtcacg ggctgcttgg acaaattttt ctgctgaaac gattgccatt
    26761 ttatcaggcc tcctgtatat ttttatgggt catcccattt acattgttca ttttatcact
    26821 ttttgccaaa aaaatctagt ttttcccgca gtttcgattg attttcttct aactccatct
    26881 atgtaaaccc tttctctccc tagtcttgga cgacttttgg aaaatctata aagaaggtta
    26941 aacgattctc ctccatctcg aaacgataag ctaatttttc atgttctaat agactcttaa
    27001 ccacaaagag ccccatacca gaccccttga ccttgcgact agcattgtca gaaaaagact
    27061 gggctagttt ttcttgttcc tctgagctac agctattttc gataaaaagt tctccttctc
    27121 tttctccaat tcgaactaag ccacctggaa cagagtgctt aatggcattg ctgatgagat
    27181 tagaaagaat caacttcata actgatgggt ttagataagc ctgctgatgg gtcaaactat
    27241 tgtctatctg gagctctctt tccttggcta acaaggcata atctttgacc agatttttcg
    27301 tcatctggag gaggtcaatt gtttccctat catctcgcaa ttcctgcaca gaagaaaggg
    27361 aaagtatctg cagaacatgg tgattgagtt catccacaat ccccaaggca actcccagat
    27421 actggtctct atccttataa cgaccgatat tctctctcat attttcgatt aggattttca
    27481 aactagccag cggtgttttc aattcatgag aagctcctcg taggaattcg accttcatct
    27541 tctccagctg gagaatggct tcattctttt catgcaagtc cgcaataaca gtcaagagat
    27601 gctggtagag gctattgatt tgttccttga gattacctat ctcatcctta gaatccacgc
    27661 gcaatcgcac ttgggaatcc aggtccatca tccgacgggt cacccgcttg atttccaaaa
    27721 tcggtgcaac aatagtccga gcgtagatgt aggccaccaa gagggaaatc agaaaggagg
    27781 ccagcaaggt atagggaaga aactggagac tgatttgctc cgcttccttt tgtaaatcca
    27841 tggaagctag aaactggaga atcatagtag caccgtcttg cgttttcacc tcgcgctcct
    27901 caataaagag agaggttgtc tggcggtctg tgtccagagg aagactgtcc ttgacttcta
    27961 acttgtcctc ggtcatctca cctttgacgg tccccttgat atcactagtc tgggaataca
    28021 agtctaacac ttgctcgata ctctgcctat ctttcccttc tagggactgg gcaatggctg
    28081 ttgccttttg accaatggtt tcctgacgat gactcagata agtcgaagga aaaagaaaat
    28141 aaatagctaa atgaaggcag ataaccagaa cactaaatat cgagaaggta tagataaata
    28201 tctttgtaaa taaacctgtt cgtttcattt tcgctccaat ttataaccaa cattgcgcac
    28261 agtgaggata caatccaagt ctagcttttt ccgcaattcc ttgatataaa catcaataac
    28321 acggtcaaag ggaacctcat ctgtcgcttt ccagacggca tcgataatct gagaccgagt
    28381 caaggcccgg ccttcatttt tcactagata gtccagaatt tccaactctt tggcattgat
    28441 aggcacttct tgacctgcga ggcttgcact gtagctttca aagtccacct tggtatcctt
    28501 gtaagaaaag attcgtcctg tatcgtagta gcgcttgaaa atcgcgtcca ccctcacttt
    28561 taagagggag agagagaaag gtttttccag atagccatct gccaaagagg caaaggcact
    28621 catcttgtat tcctcatcct gaaaagctgt caacatcaag acaggaacct gactggtttt
    28681 acgaatctca gctaggactt ctaagccgtt aagcttgggc atctggatat ccagtaaaac
    28741 cagggccacc tcatagctag aaaattgctc cagagcttcc tgaccgtccg ctgcctcaat
    28801 agtttcatag ccacaatccg tcaaataatc actgaccccc tcacggatca tctcttcatc
    28861 ttctacaatt aaaattttca tactttaact gctctctatt ttttattttt cttagaataa
    28921 atacctactc tattttctat tatagtctct tgctggcctt ttgtctgtaa gcaactgatc
    28981 actagataaa acgttgtgaa attcctttct cataaattcc ataactttag tatattatat
    29041 ttaagcacta aagtacaaag aaagcaactg aaagcaatga ttttcaccac tgctttcaga
    29101 tttattttga attgttaaat agctattcct atccactatt cttgaataga aacacaagat
    29161 gcaatcttta ttccagactc attttttcaa atttattcac catccagcaa gagctctttt
    29221 ggttgttttc taaggagatt gcttgaagca agcgccataa cgagaaccac tagaaccaag
    29281 gcaaggacaa aaatgatgat aaagtctgat gtctgaatgg aaatgtctag gctcgacaag
    29341 gtcttgctaa agccatctac ttctgcaccg ccaccaaggt tagaggcttg agccgcctta
    29401 ctagcctgtt tggcaacacc tgaagtcaca ttggcaagga cagtgtttcc aattgcacgg
    29461 gcagtgtaat tagctaggaa gtaagcagaa actagagcag ggatagcaat caagatagat
    29521 tcggtgatga attgacccaa gatacttgcc tgcttgaggc cgatagagag gagaattccc
    29581 acttccttgc gacgggcgtt gatccaaagg ctgagcaaga gggcaaggag gagaactgag
    29641 aagctcaagc taccccagaa gaggaggttg gccatcttgt acataccaga gatagattgc
    29701 tcaagagctg ggtagttaga ggagctcttg acgagtgtgt agctcttcca gttgatacca
    29761 ctgatgccat tcaactcttt cataacatca tccaagttct tgtctgctgt tacaaagaag
    29821 gttgcgtccc cataaatggc tgtgtcttct gtgtatccat aaagttttgc agcagtgtga
    29881 atgtctgtaa tagctgtgtt ttcgtaaagt tcttgtgagt aggttactgc tgacttatta
    29941 tgaccatcaa agagtccctt gattgtcact tcaactgttt ccttggctcc tttttcatta
    30001 tctgcatcgt agatattaga gtccagttta accttgtccc ctactttcca gccgtgtttg
    30061 gctgccaagt ccttgtgcaa gaggatttta tccttgtcgt cgttggttaa gtgctctcct
    30121 tcgactagtt tataagaacc agagacaaac ttatcttctt tagaggagtc attgacacct
    30181 gtaatcatca agctacttcc aaaacgcttg gcacgatcag cagtgagatt cttcttggtt
    30241 tctggcgttt caatcaggtc atatccagtc aaatctccga tagcgttgat acgtttgaca
    30301 taagactcga tggccttgtt ttcggtgatt tttttgatgt cttcaccctt gatattccca
    30361 gcaccacgag gcgttccttg gttgacgcga cgattgattt gcatggagaa gctattggtg
    30421 atatttttaa aggtctcctg agaagccttg gcagtagctc ccttgattga caagccgacc
    30481 aaactcaagc tcgccatgag gaaaataatc aggaagatga caatcgattt gaaaaacttc
    30541 cttgtaacat aggcaaatgc gttgtgtaac atagattccc tttctagatt ttgttttaat
    30601 cattctatca aaataagctc aaattattta ctagtattgc gcgtttcagt cagtttctta
    30661 tcctttaatt caagtgtaat atctgacgct tgtgccactt ctttactgtg agttacgaca
    30721 atcacacatt tacctgtttt ctgggcaagt gatttgagta gttcgacaat atctccagca
    30781 gttttaggat ccagatttcc tgttggctca tcagctagaa taactggagc ttctgagacc
    30841 aaactgcgag caatggcaac acgttgctgt tgaccacctg ataactggag aacattccgc
    30901 ttgatctggc tttcatccaa accaagctca agaagtgtat tcttgcttgc ctttttgttg
    30961 accaatcgga tattttccag cggagaaaga taatctatca agttataatt ttgaaagacc
    31021 agggaaatat ggtgcatgcg atggtaagaa tagcccttct tacgaatatc ctctccttga
    31081 aaaaggatag aaccttcaac aggactatct agaccagcaa gtagggacaa gagtgtggat
    31141 tttcctgctc ctgactcccc aataatactg taaaattttc cgggttcaaa attataatcg
    31201 atctgatata ggactgcttc agcagtattc ttataacggt aggtaacatc ttgtaattgt
    31261 aataaagtca tgatttctcc ttcttaacta atagatgata aaatttcttt cggtgatttt
    31321 ctaaataaga ataggaaaca aagggctaca gataagcaac taagcagaac tagaaaaaca
    31381 taggattctg caaaagataa gatactagtt gataaactgc ttgctttggc tagtgtatct
    31441 tgtaagcttg cctgatctcc acttgctagt agagtttgga gtaggtaagt tgtgattccg
    31501 tttcctgcaa caaatgctgg aagcaaagct ccaagagata ccaaaactac ctctaaacag
    31561 aattgtagga agatcgagct cttgcctttt ccaagtgcaa gtaaaatccc cacttcatag
    31621 acccgttctc tcaaccagag agacaaaacc agaattaagg ctccagctcc tgctatcaac
    31681 atcccataaa ggaagatggt caggaaggtt tggaaagttg caactgagtc tttgatttgt
    31741 tcaaaagcct tgttttcctt ttcgacttgg tagccttgat tttccaaggc caagttttct
    31801 acctgcttca tgagtccgtc catttcctta ggattttcta catagaagcg tgctgcactg
    31861 acttgagctt cactattgcc caaaagggtt tggctacttt catagtctgt aaagacttga
    31921 ttttcactga agtcagaaga caagcctgtg aatttctctt gttttttacc agaaaagatg
    31981 ccgataatct caaactctac tgtttgtcct tttccagatt cagactgacc agcatccaag
    32041 ccaatcttgt catgaagtga aagaccgttc ttcttagcca attcttcgtg gataaggatt
    32101 ttcttggaat cccctttttg aaggtgtcgc ccttctttta gattgaaagc cgaactggta
    32161 aaggttacat ccttggatga atcctcaaga gccgttaagc taaccaagtt attgtctgca
    32221 gctgataaat catcacgctc cacgctctgc tcgccagtca ctgcttcctt gtcttttagt
    32281 tttgcgaccg tctcaagttc aggagagaca ttttccagcc ccttaatctt gcttacagat
    32341 gctaggtctg acaacttgaa tgtctgacca ttctctatct tcttaataga aaaagatgta
    32401 ttgagtgatt tataaagatt gctttctact gttttgttgg acttcatcag agtcaaacag
    32461 gctgaaattc cggccaataa gaccaataaa atcagaaata aaataaaact tctcagtcgc
    32521 tttctgctga cataagccca agatctttgg attggattca tttgtcacct ccatatttgt
    32581 aagactatta taaaacccaa atatgaaatg tttatgaaat acgaaaaaaa aatatcgagt
    32641 aggggataat ctctagcccc tctcacacca ccgtacgtgc cgttcggcat acggc
//
LOCUS       DAVHTH010000022        30493 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.022, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000022 DAVHTH010000000
VERSION     DAVHTH010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 30493)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30493)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30493
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.022"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            <1..690
                     /gene="yaaA"
                     /locus_tag="VVR63_001038"
     CDS             <1..690
                     /gene="yaaA"
                     /locus_tag="VVR63_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HEU6129065.1"
                     /translation="DLPSIETTLLRSESQAVLDALALYSASQLESFYKVSAEKAAEEC
                     QNIQALKRQTAQHYPALKLFDGLMYRHIKRDKLTEVEQAYLENHVFITSALYGVVPAL
                     SPMAPHRLDFLMKLKVAGKTLKSHWKAAYDEAVKQEEVIFSLLSSEFETVFSKEIRAK
                     MVTFKFMEDRGGQLKIHSTISKKARGAFLTALIENQVQTVGEARRLNFAGFVYREDLS
                     QPQGLVFVKEV"
     gene            complement(741..2225)
                     /locus_tag="VVR63_001039"
     CDS             complement(741..2225)
                     /locus_tag="VVR63_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003096885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU6129066.1"
                     /translation="MRNLLSTKVQRQLRLMETLIQNRNWMKLHELAEKLGCTERILKS
                     DLNELRIAFPSINIQSSVNGIMIDLEVNTSVEDIYQYFLANSQSFQLLEYMFFNEGLP
                     IYRTIENLYFSSANLYRLGRNITKVLSSQFQIELSFTPSEIRGNEIDIRYFFAQYFSE
                     RYYFLDWPFPDLPEEDLTEFADFFYKITNYPMRFSIYRMYKLMIAISIHRVKNGHFID
                     LPNHFYKEYYPLLKSIPNFQETLAYFSKHFGLEMTPDTIAQIFISFLQNDIFLDPQEF
                     FNSLEDNSQARYSYQLLSQILERLSKQYKITFTNHDELIWHLHNTAFFERQEIFSTPI
                     LFEQKALTIKKFEVYFPDFMGSARQELAQYRQAIGQHDHPEQLEHLMYTILTHAENLS
                     TQLLENRPPIKVLIISNFDHAISLTFVDMLSYYCNNRFTFDIWDELKTSPEILNQTDY
                     DIIVSNFYISGITKKFICRNHLSIMNLVNHLNTLSNEIHLSNTL"
     gene            2441..7711
                     /locus_tag="VVR63_001040"
     CDS             2441..7711
                     /locus_tag="VVR63_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEU6129067.1"
                     /translation="MKHSHKKSFDWYSMQQRYSIRKYYFGAVSVLLGTALVLGAAASV
                     QTVQAEENKQETTNSISVGRGEAATKPAEVSASNKEKTYAAPTVANPVETTPVKTGEV
                     TKPAEKVEEAKDKKEEVTHQDAIDKSKLLTALSRAKKLESKLYTEASAANLQTSIQAG
                     QSLLGKADASEAELSAAESSIQSSIIGLELRSNSNKGTVSETPVAKKANIVEAKEETK
                     PAVTTTERSAVDSAILPISTAAKVETTSAPASTNEILKPSLSLSDARQNPAIRKEDVD
                     RGYSGFRTAGSGFRAAGSGFRAAGPENKPILNPNNTIAFSDISQGLHSFRGIGHSRGG
                     REIHYDVTTVRRGNRLNFTIKYSGPGEFVNNNFILDKGDGFGNPSNATITSSNPRVRE
                     QSKSISQGANYVSHSGYSMTSATSTNTEQTIRFSLPIINPNGDLSVRLKPVTFNVDQG
                     GGGAATSNDPYSNSNYYHRANPLLLDANPYGGTNNKTVSEDIDFQTVYLPTSKLPEGQ
                     TRLVREGEKGQRQITYKVHRFGNETLLGLPISNRVTKEAKPRIMQIGVAKELIDTVKP
                     RVDQNKVGDTNNLTFYLDNDGNGVYTEGVDELVQKIAIKDGAKGEKGDQGERGLTGAQ
                     GAKGEKGEQGLQGRDGEQGPKGEDGKTPTVKVTDGQDGTHTITINDGKGGITTTVVRD
                     GFDGASPLVSTHRNEADKTTTVIFYYDLNDNNQFDEGDTKLKEVVIADGKQGPKGDKG
                     DNGKDGFTPEVTVTDNNNGTHTITITQPDNRPSLTTIVKNGEDGKTPKVKAERDDAKK
                     QTTLTFYIDKDGDGSYTAGKDELVQTTVVKDGQDGAAGASGRDGKEVLNGKADPTTEG
                     KDGDTFVNTQTGDVFVKKGNTWEPAGNIKGPKGDKGADGAKGEKGDRGERGLTGAQGT
                     KGEKGDQGERGLTGAQGTKGEKGDRGERGLTGAQGQAGRDAVTPTVTVKDNKNDGTHT
                     ITINDGRGNVASTVVRDGFDGASPLVATQRNEADKTTTVIFYYDQNGNNELDASDKKL
                     KEVIIADGAKGEQGLQGRDGQDGAQGQAGRDGKDVLNGKANPEVNQGKDGDKYVNTET
                     GDVFVKNNGNWDKEGNIKGPKGDKGERGEDGKTPEVTVTPGKDGHSTDITFTVPGKDP
                     VTFTVKDGKNGKDGRAPKIKVEDITSPSRIRRDTDAAATPTRNGIRVTVYDDVNDNGV
                     YDEGVDKVLNSKDIYNGIDGRDGSAPTITTKDNGDGTHTITVQNPDSSESTTVVKDGK
                     DGKTANITTTENPDGSHTITVTNPDGSTKETVVKNGKDGKTPKVEVTDNNDGTHTVKV
                     TDGDGNVTNAIIKDGKDGKAATATTTENPDGSHTVTITNPDGTKNEFVVKNGRDGVDG
                     RTPTASVRDNGDGSHTIVITNPEGVTTETTVRDGKSPKVTITDEQNGTHKISVLNGDG
                     TTTETIIKDGKSPVATVRDNQDGTYTIRVENGNGTVSETTVRDGKSPTAKVVDNGDGT
                     HTITVVNSDGTTTTTTVRDGREPKLEVIDNNDGSHTIKVTGADGKGTTTTIFDGKSPK
                     ANIVDNGDGTHTLTIVDSDGREYKSIIKDGKDGKDSVSPTVTVKNNNDGTHVVTITNP
                     DGSKTEMVIKDGKDGKCGCQDKPVTPSNDKPVPPTPNVPTPEVPVKPVPAQPTPNVPT
                     PEVPVQPTPAVPTPEVPVKPVPAVPEQPVVPTPAQPATPVNANPVAPTTGKENRGDKL
                     PETGSQSDYISVLLGSGILLSLYVGRRKED"
     gene            complement(7948..8496)
                     /locus_tag="VVR63_001041"
     CDS             complement(7948..8496)
                     /locus_tag="VVR63_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEU6129068.1"
                     /translation="MSKKVLFIVGSLRQGSFNHQMALEAEKALAGKAEVSYLDYSALP
                     LFSQDLEVPTHPAVAAAREAVLVADAIWIFSPVYNFSIPGTVKNLLDWLSRALDLSDT
                     RGVSALQDKFVTVSSVANAGHDQLFAIYKDLLPFIRTQGVGDFTAARVNDSAWADGKL
                     VLEETVLNSLEKQAQDLVEAIQ"
     gene            8817..9305
                     /locus_tag="VVR63_001042"
     CDS             8817..9305
                     /locus_tag="VVR63_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HEU6129069.1"
                     /translation="MKKRQNKAKNNLLWQYGLGMTILFVVISGSFLYMVSLSMKPYQT
                     AKSEGEKLAQQYAGLEQVDQVDLYNGLESYYSVLGRNKQQEALAVLIGKDDHKIYVYQ
                     LNQGVSQEKAETVSKEKGAGEIDKITFGRYQDKPIWEVKSGSDFYLVDFETGALVNKE
                     GL"
     gene            9302..10489
                     /locus_tag="VVR63_001043"
     CDS             9302..10489
                     /locus_tag="VVR63_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEU6129070.1"
                     /translation="MKLSNRVLEMEESVTLAAGARAKALKAEGRDILSLTLGEPDFTT
                     PKNIQDAAIASIRDGRASFYTVTSGLPELKAAVNSYFERFYGYSVASNQVTVAAGAKY
                     SLYTFFMAVVNPGDEVIIPTPYWVSYGDQVKMAEGVPVFVSTKEDNHFKVTVDQLEAA
                     RTDKTKVLVLNSPSNPTGMIYTREELLAIGNWAVENDILILADDIYGRLVYNGHEFTP
                     ISSLSEAIRKQTVVINGVSKTYAMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQ
                     YAAVEALSGEQDTVESMRQAFEERLNTIYPLLAEVPGFEVVKPQGAFYLFPNVKKAME
                     MKGYTDVTDFTTAILEEAEVALVTGAGFGAPENVRLSYATDLDTLKEAVERLKAFMGS
                     END"
     gene            10482..10847
                     /locus_tag="VVR63_001044"
     CDS             10482..10847
                     /locus_tag="VVR63_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEU6129071.1"
                     /translation="MIDHFEIKVKDLQISEGFYRSFLAPLDYKLAFKTSSLISFLSPN
                     SPHPGGDFWLTQGTQDPVHFAFLAENKEEVQACYEAGLEAGGRDNGAPGYRSEHPIYY
                     AAFMIDLDGNNIEVVCHKE"
     gene            10863..12209
                     /gene="asnS"
                     /locus_tag="VVR63_001045"
     CDS             10863..12209
                     /gene="asnS"
                     /locus_tag="VVR63_001045"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HEU6129072.1"
                     /translation="MMTKRVTIIDVKDYVGQEVTIGAWVANKSGKGKIAFLQLRDGTA
                     FFQGVAFKPNFVEKFGEEVGLEKFDVIKRLSQETSVYVTGIVKEDERSKFGYELDITD
                     IEVIGESQDYPITPKEHGTDFLMDNRHLWLRSRKQVAVLQIRNAIIYATYEFFDKNGF
                     MKFDSPILSGNAAEDSTELFETDYFGTPAYLSQSGQLYLEAGAMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYSYLTHDESLDLQEAYVKALLQGVLDRAPQALETLERDTE
                     LLKRYIAEPFKRITYDQAIDLLQEHENDEDADYEHLEHGDDFGSPHETWISNHFGVPT
                     FVMNYPAAIKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREEDYDALVAKMDEL
                     GMDRTEYEFYLDLRKYGTVPHGGFGIGIERMVTFAAGTKHIREAIPFPRMLHRIKP"
     gene            12362..12652
                     /locus_tag="VVR63_001046"
     CDS             12362..12652
                     /locus_tag="VVR63_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HEU6129073.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKTWE
                     KRRLAYEIQDFREGLYHIVNVEANDDAALKEFDRLSKINADILRHMIVKIDA"
     gene            12664..13134
                     /gene="ssbA"
                     /locus_tag="VVR63_001047"
     CDS             12664..13134
                     /gene="ssbA"
                     /locus_tag="VVR63_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein SsbA"
                     /protein_id="HEU6129074.1"
                     /translation="MINNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGER
                     EADFINVVMWRQQAENLANWAKKGSLIGVTGRIQTRSYDNQQGQRVYVTEVVAENFQM
                     LESRSVREGHTGGAYSAPTANYSAPTNSVPDFSRNENPFGATNPLDISDDDLPF"
     gene            13166..13405
                     /locus_tag="VVR63_001048"
     CDS             13166..13405
                     /locus_tag="VVR63_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HEU6129075.1"
                     /translation="MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPFVNED"
     gene            13700..15100
                     /locus_tag="VVR63_001049"
     CDS             13700..15100
                     /locus_tag="VVR63_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional Cof-type HAD-IIB family
                     hydrolase/peptidylprolyl isomerase"
                     /protein_id="HEU6129076.1"
                     /translation="MDAKLRYKAKKIKIVFFDIDDTLRNSKTGFIPTTIPTVFKQLRE
                     KGILTGIASGRGIFGVVPEIRDLKPDFFVTLNGAYIEDKKGQVIYQHQIEKSDVEEYI
                     SWAKQEGIEYGLVGSHDAKLSTRTDMMSEAINPIYPDLDVDPDFHEKEDIYQMWTFED
                     KGDDLHLPDSLSDKLRMVRWHQHSSDIVPISGSKATGVEKVVEHLGLKPEKVMVFGDG
                     LNDLELFDYAGISVAMGISHDKIKEKADYITKTLEEDGIFDALEVFGMVEKELHFPQV
                     DIETVEGPLATIKTNHGDLRIKLFPEHAPKTVANFVSLSKDGYYDGVIFHRIIKDFMI
                     QGGDPTGTGMGGESIYGESFEDEFSEELYNIRGALSMANAGPNTNGSQFFIVQNQHLP
                     YSKKEITRGGWPEPIAEIYANQGGTPHLDRRHTVFGQLADEASYAVLDAIAAVETGAM
                     DKPVEDVVIETIEIED"
     gene            15102..15461
                     /locus_tag="VVR63_001050"
     CDS             15102..15461
                     /locus_tag="VVR63_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HEU6129077.1"
                     /translation="MKIGDKLKGRITGIQPYGAFVELETGDTGLIHISEIRTGFIENI
                     HETLKVDEEVQVQVVDLDEFTGKASLSIRTLEEEKYQFPRRRRFSSDRFNYGFAPFRR
                     MLPIWTGEALHHLKKKK"
     gene            15515..16264
                     /locus_tag="VVR63_001051"
     CDS             15515..16264
                     /locus_tag="VVR63_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HEU6129078.1"
                     /translation="MEEEQLLKSGERINQLFSTDIKIIQNREVFSYSVDSVLLSRFPR
                     FPKKGLIVDFCAGNGAVGLFASTRTQAQILSVEIQERLADMAERSVRLNGLEEQMQVI
                     CDDLKNMPAHIQGSKVDMILCNPPYFKVNPYSNLNESEHYLLARHEITTNLEEICRSA
                     QSILKSNGRLAMVHRPDRLLDILDTLKRHNLAPKRLQFVYPKREKEANMLLIEAIKDG
                     STSGFKVLPPLIVHNDDGSYTPEIEEIYYGS"
     gene            16254..16553
                     /locus_tag="VVR63_001052"
     CDS             16254..16553
                     /locus_tag="VVR63_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HEU6129079.1"
                     /translation="MDHKAYMYVLECRDGSYYIGYTTDMRRCLAIHNSGKGAKYTRAR
                     LPVKLIYAQGFASKEEAMSAEALLKRKKRPQKEEFLSENQDRNLLSYFEESWGVL"
     gene            16624..17559
                     /locus_tag="VVR63_001053"
     CDS             16624..17559
                     /locus_tag="VVR63_001053"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HEU6129080.1"
                     /translation="MSKILVFGHQNPDSDAIGSSVAFAYLAKEAYGLDTEAVALGTPN
                     EETAFVLNYFGVEAPRVITSAKAEGAEQVILTDHNEFQQSVSDIAEVEVYGVVDHHRV
                     ANFETASPLYMRLEPVGSASSIVYRMFKEHGVAVPKEIAGLMLSGLISDTLLLKSPTT
                     HPTDKIIAPELAELAGVNLEEYGLAMLKAGTNLASKSAEELIDIDAKTFELNGNNVRV
                     AQVNTVDIAEVLERQAEIEAAMQAANESNGYSDFVLMITDIVNSNSEILALGANMDKV
                     EAAFNFKLENNHAFLAGAVSRKKQVVPQLTESFNA"
     gene            17645..18157
                     /locus_tag="VVR63_001054"
     CDS             17645..18157
                     /locus_tag="VVR63_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000892254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoylalanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HEU6129081.1"
                     /translation="MLENGDLIFVRDGSDMGQAIQTSTGNYSHVAIYLDGMIYHASGQ
                     AGVVCQEPADFFESNHLYDLYVYPEMDIQSVKERACKHLGAPYNASFYPDAPGFYCSQ
                     YIAEILPIFETIPMKFGDGEQEISDFWREYYIELGLPVPLNQAGTNPSQLAASPLLQC
                     KERNLHDSDF"
     gene            18182..18790
                     /locus_tag="VVR63_001055"
     CDS             18182..18790
                     /locus_tag="VVR63_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HEU6129082.1"
                     /translation="MFGELIRYLDQYEDVILREIKAQFPDVAVDKLMEEYIKAGLILR
                     ENKRYYLNFPTLESLDSLELDQEIFVREASPVYQALLEQSFETELRNQINAAILVEKT
                     DFARIKMTLSNYFYKVKQQYPLTEKQQELYDILGDVNPEYALKYMTAFLLKFLKKDQL
                     MQKCRDIFVDSLVVLGYIVQNEDGKYELAIDFDKERLTFYLA"
     gene            18891..19100
                     /locus_tag="VVR63_001056"
     CDS             18891..19100
                     /locus_tag="VVR63_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEU6129083.1"
                     /translation="MSLENKLEQATGAVKEGFGKVTGDSKTELEGAVEKTVAKAKDVV
                     EDAKGAVEGAVEGAVEGLKNVFTKE"
     gene            complement(19143..20588)
                     /locus_tag="VVR63_001057"
     CDS             complement(19143..20588)
                     /locus_tag="VVR63_001057"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HEU6129084.1"
                     /translation="MIKIETVLDILKKDGLFREIIDQGHYHYNYSKVVFDSISYDSRK
                     VTEDTLFFAKGAAFKKEYLLSAITQGLAWYVAEKDYEVGIPVIIVNDIKKAMSLIAME
                     FYGNPQEKLKLLAFTGTKGKTTAAYFAYNILSQGHRPAMLSTMNTTLDGETFFKSALT
                     TPESIDLFDMMNQAVQNDRTHLIMEVSSQSYLVRRVYGLTFDVGVFLNISPDHIGPIE
                     HPSFEDYFYHKRLLMENSRAVIINSDMDHFSVLKEQVKDQDHDFYGSQFDNQIENSKA
                     FSFSATGKLAGDYDIQLIGNFNQENAVAAGLACLRLGASLEDIKKGIAATRVPGRMEV
                     LTQKNGAKVFIDYAHNGDSLKKLINVVETHQTGKIALVLGSTGNKGESRRKDFGLLLN
                     QHPEIQVFLTADDPNYEDPMAIADEISSYINHPVEKIADRQEAIKAAMAITNHELDAV
                     IIAGKGADCYQIIQGKKESYPGDTAVAENYL"
     gene            20694..22316
                     /locus_tag="VVR63_001058"
     CDS             20694..22316
                     /locus_tag="VVR63_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEU6129085.1"
                     /translation="MSHENNHQQAQMLRGTAWLTASNFISRLLGAVYIIPWYIWMGAY
                     AAKANGLFTMGYNIYAWFLLVSTAGIPVAVAKQVAKYNTMREEEHSFALIRSFLGFMT
                     GLGLVFALVLYVFAPWLADLSGVGKDLIPIMQSLAWGVLIFPSMSVIRGFFQGMNNLK
                     PYAMSQIAEQVIRVIWMLLATFIIMKLGSGDYLAAVTQSTFAAFVGMVASFAVLIYFL
                     AQEGSLKRVFETEDKINSKRLLVDTIKEAIPFILTGSAIQLFQILDQLTFINSMSWFT
                     NYSNEDLVVMFSYFSANPNKITMILISVGVSIGSVGLPLLTENYVKGDLKAASRLVQD
                     SLTLLFMFLLPATVGVVMVGEPLYTVFYGKPDSLALGLFVFAVLQSIILGLYMVLSPM
                     LQAMFRNRKAVLYFIYGSIAKLVLQLPTIALFHSYGPLISTTIALIIPNVLMYRDICK
                     VTGVKRKVILKRTILISLLTLVMFLLIGTIQWLLGFFFQPSGRLWSFFYVALVGAMGG
                     GLYMVMSLRTYLLDKVIGKAQADRLRAKFKLS"
     gene            22520..24478
                     /locus_tag="VVR63_001059"
     CDS             22520..24478
                     /locus_tag="VVR63_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU6129086.1"
                     /translation="MKKSKSKYLTLAGLVLGTGVLLSACGNSSTASKTYNYVYSSDPS
                     SLNYLAENRAATSDIVANLVDGLLENDQYGNIIPSLAEDWTVSQDGLTYTYKLRKDAK
                     WFTSEGEEYAPVTAQDFVTGLQYAADKKSEALYLVQDSVAGLDDYITGKTSDFSTVGV
                     KALDDQTVQYTLVKPELYWNSKTLATILFPVNADFLKSKGDDFGKADPSSILYNGPFL
                     MKALVSKSAIEYKKNPNYWDAKNVFVDDVKLTYYDGSDQESLERNFTAGAYTTARLFP
                     NSSSYEGIKEKYKNNIIYSMQNSTSYFFNFNLDRKSYNYTSKTSDIEKKSTQEAVLNK
                     NFRQAINFAFDRTSYGAQSEGKEGATKILRNLVVPPNFVSIKGKDFGEVVASKMVNYG
                     KEWQGINFADGQDPYYNPEKAKAKFAEAKKELEAKGVQFPIHLDKTVEVTDKVGIQGV
                     SSIKQSIESVLGSDNVVIDIQQLTSDEFDSSGYFAQTAAQKDYDLYHGGWGPDYQDPS
                     TYLDIFNTNSGGVLQNLGLEPGEANDKAKAVGLDVYTQMLEEANKEQDPAKRYEKYAD
                     IQAWLIDSSLVLPSVSRGGTPSLRRTVPFAAAYGLTGTKGVESYKYLKVQDKIVTTDE
                     YAKAREKWLKEKEESNKKAQEELAKHVK"
     gene            24650..26332
                     /locus_tag="VVR63_001060"
     CDS             24650..26332
                     /locus_tag="VVR63_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6129087.1"
                     /translation="MKLKLLRVDTKVIMGSFLLVLSSLLALLLPLILKGLIDGSSIEN
                     IGSKVFQSFLIFIGQALFSSIGYYLFSQSGEKKIAKIRKKVIEGLIYAEKSFFDKSQS
                     GELTSAIVNDMSVIREFLITTFPNIILSLVMVLGSIVVLFSLDWNLSLLLFITLPCMM
                     FIILPLSNISEKYSRRLQEEIGFLTGQLTEKIQEHELIKTNQAEKSVQDVLDNCIERV
                     QNNSLKSDRVTSFETPFALLFIFATIVVMLTYGGYRVSAGYISVGTLVSFLIYLFQLL
                     NPISNIANFVTIYSSSKGSSVALENLLAVPKEKFEGGKSVSGQGLNFNHVYFGYDENR
                     PVLKDITCSIFKGQKIAFVGPSGSGKSTIVRLLERFYKPLSGDILMEQSSIYDFNLKE
                     WRSKIAWVSQNNAVLSGSIRDNLCLGLNRLVTDDELMKVLDLVSLGDEIRSMKEGLDT
                     EVGERGRLLSGGRSQRLQIARAYLKDAEILIFDEATANLDADSEYAIISSLYSVLKEK
                     TVVIIAHRLSTVKDVDCIFFLEEGKITGSGTHKELLENHERYARFVQEQMIE"
     gene            26490..27584
                     /locus_tag="VVR63_001061"
     CDS             26490..27584
                     /locus_tag="VVR63_001061"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HEU6129088.1"
                     /translation="MSKELHINTILAQAGIKSDEATGALVTPLHFSTTYQHPEFGRST
                     GFDYTRTKNPTRSKAEEVLAAIESADYALATSSGMSAIVLAFSVFPVGSKVLAVRDLY
                     GGSFRWFNQVEQEGHFHFTYANTEEELIAELEKDVDVLYIETPTNPLMLEFDIEKLAK
                     LAHAKGAKVVVDNTFYSPIYQRPIEDGADIVLHSATKYLAGHNDVLAGVVVTNSLELY
                     EKLFYNLNTTGAVLSPFDSYQLLRGLKTLSLRMERSTANAQEVVAFLKDSPAVKEVLY
                     TGRGGMISFKVADETRIPHILNSLKVFSFAESLGGVESLITYPTTQTHADIPAEVRHS
                     YGLTDDLLRLSIGIEDARDLIADLRQALEG"
     gene            27592..28758
                     /locus_tag="VVR63_001062"
     CDS             27592..28758
                     /locus_tag="VVR63_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEU6129089.1"
                     /translation="MGKYDFTSLPNRLGHHTYKWKETETDSEVLPAWIADMDFVVLPE
                     IHQAVQTYADQLVYGYTYASEDLIKEVQKWEATQYGYNFDKEALVFIEGVVPAISTAI
                     QTFTKEGEAVLINTPVYPPFARSVKLNNRRLITNSLVEKDSLFEIDFDQLEKDLVEEE
                     VKLYVLCNPHNPGGRVWEKEVLEKIGQLCQKHGVLLVSDEIHQDLTLFGHKHQSFNTI
                     NPAFKNFAIVLSSATKTFNIAGTKNSYAVIENPKLRLAFQKRLLANNQHEISGLGYLA
                     TEAAYRYGKDWLEELKQVFEDHINYVVDLFGKETKIKVMKPQGTYLIWLDFSAYDLTD
                     ETLQELLRNEAKVILNRGLDFGEEGSLHARINIAMPKSLLQEVCQRIVATFAKC"
     gene            28851..>30493
                     /locus_tag="VVR63_001063"
     CDS             28851..>30493
                     /locus_tag="VVR63_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SNF2 helicase associated domain-containing
                     protein"
                     /protein_id="HEU6129090.1"
                     /translation="MAKLIPGKIRIEGVALYETGKVDIIKEKNNRLYARVAEEELRYS
                     LEDDLIFCACDFFQKRGYCVHLAALEHFLKNDERGQEILWSLEEGHEEKEAVETKVTL
                     GGKFLDRILSPKSECAYELSAVGQVEAGTNHILWTLRIGQINSQKYYVIRDIPLFLRI
                     VEQRKSYMIGKIYEESLSWEAFDDASQELLTFLHGLTEEGLVPDLFFQNQGRHLFFPL
                     TFFEQGVNLLMALPHFQFDHQVDSYQTLLFQDMHADANLFAFTVTEYSDYFEMEISES
                     PRVNVFYQGAVLFHKGQVYFLTDQQMRLLKEIKALPVDRQGKKYLQFDSSDRDKLASC
                     LTLFIQMGTVSAPERLQIKTFAPSFYFDREEDNRIRLEIQFDYGNRQVSSRQELEELP
                     FSSDADLEERIFQVCLAAGFEADFQSWRQALKAESVYHFFHDIIPVFEKLGHVDLSDK
                     LEELYSLASPQVQIASKGGLLEIQFDFQDIAQEEIDQAIQALVANQDFYIDSSNQVYF
                     FDEETKKIRQNLQELGQFELKDGTLQARKSLAYSLAHLF"
BASE COUNT         9520 a         5533 c         6772 g         8668 t
ORIGIN      
        1 gacttgccga gtatcgagac aactctttta agatcagaaa gtcaggctgt acttgatgcc
       61 ttggctctct attctgccag tcaattggaa agtttctaca aggtatcagc tgagaaggct
      121 gcggaagaat gtcaaaatat ccaagctttg aaaaggcaaa ctgctcaaca ctacccagcc
      181 ttgaagcttt ttgatgggct tatgtaccgt catatcaaga gagacaaact gaccgaggta
      241 gaacaagcct atcttgaaaa tcatgtcttc attacctcgg ctttgtacgg agtcgttcca
      301 gccttgtcgc ctatggcacc tcaccgtttg gattttttga tgaaattaaa agtcgctggt
      361 aagactttga agagccattg gaaggcagcc tatgatgaag ctgtgaagca ggaagaagtg
      421 attttctctc tcttgtcatc agagtttgag actgtatttt ctaaggaaat cagagcaaag
      481 atggtgacct tcaaattcat ggaggataga ggcggtcagc tgaagattca ctcaactatc
      541 tccaagaaag cgcgcggggc ctttctaaca gctttaatag aaaatcaagt acaaactgtg
      601 ggggaagcac gtcgcttgaa ctttgctgga tttgtttacc gagaagattt gtcacaacca
      661 cagggattgg tttttgtaaa ggaagtatag aaatcagata agagaaaagt cagcacgatt
      721 atgctgactt ttttgataac ttataaagta ttggacaaat gaatctcatt tgataaggtg
      781 ttaagatgat taaccaaatt catgattgac agatgatttc ggcaaataaa cttcttggta
      841 atccctgaaa tatagaaatt agacacgatg atatcgtaat ctgtctgatt taaaatctca
      901 ggacttgttt ttaattcatc ccaaatatcg aaggtaaagc ggttattaca gtaataggaa
      961 agcatatcaa caaaggtaag ggatatagca tggtcaaagt tactgataat caaaaccttg
     1021 ataggtggtc gattttctaa caactgagta gagaggtttt cagcatgggt taagatggtg
     1081 tacatcaagt gttccaactg ttcaggatgg tcatgctgtc caattgcctg acggtattga
     1141 gccagttctt gacgcgcact tcccataaag tctgggaagt aaacttcaaa ttttttaatc
     1201 gtcaatgctt tttgttcaaa taagattggg gtagaaaaga tttcctgtct ttcaaagaaa
     1261 gcagtgttgt gtaaatgcca aatcagctca tcgtggttag taaaagtaat cttatattgt
     1321 tttgataggc gttctaatat ttgactaagt aattggtaag agtatcttgc ttgactgtta
     1381 tcttctaaag agttgaagaa ttcttgagga tctaggaaaa tatcattctg aagaaaagaa
     1441 ataaaaattt gagcgattgt atctggagtc atttcaagcc caaaatgttt agagaaataa
     1501 gcaagtgtct cctggaaatt tggaatgctc tttaaaagag gataatattc tttgtaaaag
     1561 tggttgggga ggtcaatgaa gtgaccattt ttaaccctgt ggatactgat agctatcatc
     1621 agtttgtaca ttctataaat tgaaaatcgc attggataat tcgtgatttt atagaagaag
     1681 tcagcaaact ctgttaaatc ttcctcagga aggtcaggaa aaggccaatc taggaaataa
     1741 tagcgctcag aaaagtattg ggcaaaaaag taacgaatat cgatctcatt tccacgtatc
     1801 tcggatggag taaaagataa ttcaatttga aactgagatg aaagaacctt tgtaatattt
     1861 ctgcccagtc gatagaggtt ggcactacta aagtaaagat tttctattgt tcgataaata
     1921 ggtagcccct cattgaagaa catatactct agtaattgaa aagattgaga attagcaaga
     1981 aaatattgat aaatatcttc tacactagtg ttaacttcta aatctatcat gattccgtta
     2041 acagaagatt ggatgttaat agatggaaag gcaatacgta attcatttaa atcacttttt
     2101 aagattcgtt ctgtacatcc taatttttcg gctagttcat gtaatttcat ccaattacga
     2161 ttctgaatta gggtttccat taagcgtaat tgtctttgaa cttttgtgga taaaaggttt
     2221 ctcatacggg tatttcctcc ataattcatt atatcttttt ttgtctaagt agtataaaaa
     2281 aattagagca agaaaattgt cgttagtaat cggaaaaatt agaataatat aagtggcttt
     2341 taagtgcaaa aacagaatat attaattgtt cagaaaatat tgattaatgc ctcaaatagt
     2401 tgtacattgt aaactataaa atactatcta ggagtttaaa atgaaacatt cacataaaaa
     2461 atcatttgac tggtatagca tgcaacaacg ttattctatt cgtaagtatt actttggtgc
     2521 agttagtgtc ttgctcggta ccgctttggt attaggtgca gcagctagtg tccaaacagt
     2581 acaagcggaa gaaaacaaac aagaaactac caatagtatt tctgttggta ggggagaagc
     2641 agctactaaa ccagcagagg tttctgcgtc taataaagag aaaacctatg cagctccaac
     2701 tgtagctaat ccagtagaaa cgactccagt taaaactgga gaagttacta aaccagcaga
     2761 aaaagttgaa gaagcaaaag acaaaaaaga ggaagtaacg catcaagatg ctattgacaa
     2821 gtcaaaattg ttaacggctc tttcgcgtgc taaaaagtta gaaagcaagt tatatacaga
     2881 agcaagtgct gctaacttgc aaacaagtat ccaagctggt caaagcttgc ttgggaaagc
     2941 agatgcatct gaagctgaat tatcagcagc agagtcatct attcaatcat ctattattgg
     3001 tctagaactt cgttctaact ctaacaaagg aactgtatca gaaacgcctg tagcaaagaa
     3061 agctaatata gttgaagcga aggaagagac taaaccagct gtaacaacga ctgaacgttc
     3121 agctgttgat agcgctattt tgccaattag cacagctgct aaagtagaaa caacttcagc
     3181 tccagcatct actaatgaaa tcttgaaacc aagtttgagc ctttctgatg ctcgccaaaa
     3241 tccagctatc cgtaaggaag atgttgatag agggtatagt ggttttagaa cagcaggaag
     3301 tggctttaga gcggctggaa gtggttttag agcagctgga ccagaaaata aaccaatctt
     3361 aaatccaaat aatactattg cattttctga catcagtcag ggcttacatt catttcgtgg
     3421 tataggacat tcacgtggtg gtcgtgaaat ccattatgat gtaacgacag tacgtagagg
     3481 taatagattg aatttcacaa ttaaatactc tggtccaggt gaatttgtta ataataattt
     3541 tatcttggat aaaggggatg gatttggaaa tccttcaaat gcaacgatca caagttcaaa
     3601 tccaagagta agggagcaat caaaatctat tagtcagggt gccaactacg tatctcactc
     3661 aggatacagt atgacctctg ctacttcaac aaatacggaa caaactatca gatttagttt
     3721 gcctatcatt aatccaaatg gtgatttgtc tgttcgtttg aaaccagtta cttttaacgt
     3781 ggaccaaggt ggtggtggtg ccgctactag caatgaccca tacagtaact ccaactatta
     3841 tcatagagca aatccactcc tcttggatgc aaacccttat ggtggtacta ataataagac
     3901 tgtttcagaa gacattgact tccaaactgt ctatcttcca actagtaagt taccagaagg
     3961 tcaaactaga ttagttcgag aaggtgaaaa aggacaacgt caaattacct ataaagtaca
     4021 tcgatttggt aacgaaacac ttttaggatt gccaattagt aatagagtta ctaaagaagc
     4081 taagccacgt attatgcaaa ttggtgtggc taaagagtta atcgatacag taaaaccacg
     4141 tgttgatcaa aataaagttg gtgatacaaa taacctcact ttctatcttg ataacgatgg
     4201 aaacggtgtt tatactgagg gcgtagacga acttgttcaa aaaattgcta ttaaagatgg
     4261 agccaagggt gaaaaagggg accaaggtga acgcggtcta accggagccc aaggagctaa
     4321 aggtgaaaaa ggtgaacaag gtcttcaagg gcgtgatggt gaacaaggac caaaaggaga
     4381 agatgggaaa accccaacag ttaaagtaac tgatggtcaa gatggaacgc atacaattac
     4441 aattaacgat ggtaaaggtg gtataactac tacagtagta agagatggat ttgatggtgc
     4501 aagccctctt gtttctactc atagaaatga agcagataaa acaacaactg ttattttcta
     4561 ttatgatcta aatgataata atcaatttga tgaaggagat acaaaactta aagaagttgt
     4621 tatcgcagat ggaaaacaag gaccaaaagg tgacaaaggt gataacggaa aagatggatt
     4681 cacaccagaa gtaacagtta cagataacaa taacggaaca cacaccatca caatcacaca
     4741 accagacaac agaccatcat taacaacaat cgttaaaaac ggtgaagatg gaaaaacacc
     4801 aaaagtcaaa gcagaacgag atgatgcgaa gaaacaaaca acattaacat tctacattga
     4861 caaagatgga gatggaagtt acacagcagg aaaagacgag ttagttcaaa caacagtagt
     4921 taaagacgga caagacggag ctgcaggagc atctggacgt gatggaaaag aagtattaaa
     4981 cggaaaagca gacccaacaa cagaaggtaa agatggagac acattcgtaa atacacaaac
     5041 aggagatgta ttcgttaaga aaggtaacac ttgggaacca gcaggaaaca tcaaaggacc
     5101 gaaaggtgac aaaggtgcag atggtgctaa aggcgaaaaa ggagaccgag gcgaacgcgg
     5161 tctaaccgga gcgcaaggta ctaaaggtga aaagggagat cagggtgaac gcggtctaac
     5221 cggagcgcaa ggtactaaag gtgaaaaagg agaccgaggc gaacgcggtc taactggagc
     5281 gcaaggtcag gcaggtcgtg acgctgtaac tccaaccgta accgttaaag ataataaaaa
     5341 tgacggcact catactatca ctattaacga cggtagaggt aatgttgcaa gtactgttgt
     5401 aagagatggt ttcgatggcg caagtccatt agttgcgact caacgaaatg aagcagataa
     5461 gacaacaact gttatcttct attatgatca aaatggaaat aatgaattag atgcttctga
     5521 taagaaatta aaagaagtta ttattgcaga tggtgccaaa ggtgaacaag gtcttcaagg
     5581 tcgtgatggt caagacggag ctcagggaca agcaggacgc gacggtaaag acgtgttgaa
     5641 cggcaaagct aatccagaag taaatcaagg taaagatggt gataaatacg tcaatacaga
     5701 aacaggcgac gtcttcgtta agaataacgg caactgggat aaagagggca acatcaaggg
     5761 acctaaaggg gacaaaggtg aacgcggaga agatggtaag actccagaag taactgtaac
     5821 tccaggtaaa gatggccata gtactgacat tacattcact gttccaggta aagatccagt
     5881 aaccttcact gtaaaagatg gtaagaatgg taaagatggc cgtgcaccga aaatcaaagt
     5941 agaagatatt acttcacctt caagaattag acgcgataca gatgctgctg caactccaac
     6001 gcgtaacggt atccgtgtta cagtttatga tgatgttaat gacaatgggg tatacgacga
     6061 aggtgtcgat aaagtattaa atagtaaaga tatttataac ggtatagatg gacgtgatgg
     6121 ttcagctcca actattacta caaaagataa tggagatgga actcacacta tcacagttca
     6181 aaacccagat agttctgaat caacaacagt tgttaaagat ggtaaagacg gtaaaactgc
     6241 gaatatcact acaacagaaa acccagatgg aagccacaca attacggtga caaatccaga
     6301 tggttcaact aaagaaactg ttgttaaaaa cggtaaagac ggtaagactc ctaaagttga
     6361 agtaacggat aacaacgatg gaactcatac tgttaaagtt acagatggag acggcaatgt
     6421 taccaacgct atcatcaaag atggtaaaga cggtaaagct gcaacagcaa caactactga
     6481 aaatccagat ggaagccaca cagtaacaat cactaaccca gacggaacta agaatgagtt
     6541 tgttgttaag aatggacgtg acggtgttga cggacgtact ccaaccgcat ctgttcgtga
     6601 taatggagac ggaagtcata caatcgttat tacaaatcca gaaggtgtga caactgaaac
     6661 cacagttcgt gatggtaaat caccaaaagt gactataact gatgaacaaa atggaactca
     6721 taagatctct gttctaaatg gtgacggaac aactactgaa acaatcatta aagatggtaa
     6781 atcaccagta gcaacagtta gagataacca agatggtact tacactattc gtgtggaaaa
     6841 cggtaatggt actgtttctg aaaccacagt tcgtgacggt aaatcaccaa ctgctaaggt
     6901 tgtggataat ggagatggaa ctcacactat cacagttgtg aactcagacg gaacaactac
     6961 aacaactaca gttcgtgatg gtagagaacc aaaacttgaa gttattgata acaacgatgg
     7021 ttcacacact attaaagtga caggtgctga tggtaaagga acgacaacta caatctttga
     7081 tggtaaatca ccaaaagcga acatcgttga taacggagat ggaactcata cattaacaat
     7141 cgtagattct gatggtcgtg aatacaaatc tattatcaaa gatggtaaag acggcaaaga
     7201 tagcgtttca ccaactgtaa ctgttaaaaa taataacgat ggaactcacg ttgttacaat
     7261 cactaatcca gatggaagta agacagaaat ggtgattaaa gacggtaaag atggaaaatg
     7321 tggatgccaa gacaaaccag taacaccatc aaatgacaaa ccagttcctc caacaccaaa
     7381 tgtgccgaca ccagaagtac cggttaaacc tgtgccagcg caaccaacac caaatgtacc
     7441 gacaccagaa gtgccagtac aaccaactcc agctgttcca acaccagaag taccggttaa
     7501 accagtacca gcggttccag aacaaccagt agtaccaaca ccggctcaac cagcaactcc
     7561 agtaaatgct aatccagtag caccaactac aggtaaagaa aaccgtgggg acaaattacc
     7621 tgaaactgga agccaatctg attatatctc tgttctttta ggtagcggta ttctattgag
     7681 cctatatgta ggacgaagaa aagaagatta atcagccaaa agcagtcact aatttctcga
     7741 aagaagatga taagtgatag atctcgaatg aaagaatatt cttagaatga ttttcctatg
     7801 atggaaaaga ctgctaaaaa ccttgagtgg taacgctcaa ggtttttttg gatggctgat
     7861 gtttgtctga aaatcttgat tgagaaataa aaagccaccc tattaggtgg ctataattga
     7921 tttagacttt ctaaaatttt ctatttttta ctgaatcgct tcgaccaagt cttgagcttg
     7981 tttttcaagt gagtttagga ctgtttcttc aagaaccaat tttccgtctg cccaggcaga
     8041 gtcattaaca cgtgcagcag tgaaatcacc aacgccttgt gtacggataa atggcaagag
     8101 gtctttgtag atagcgaaaa gttgatcgtg ccctgcattg gctacagatg atactgtgac
     8161 aaacttgtct tgaagggcag aaacgccacg tgtatcagac aagtcaaggg cacgagatag
     8221 ccagtcaagc aagtttttca ctgtaccagg gatagagaag ttgtagactg gagagaaaat
     8281 ccagatagca tccgcaacga gaactgcttc acgagcagca gctacagctg gatgtgttgg
     8341 aacttccaaa tcttggctga agagaggaag ggctgaataa tcaaggtagc taacttccgc
     8401 tttaccagca agtgctttct cagcttcgag cgccatttgg tggttgaaag aaccttgacg
     8461 tagtgatccg acgataaata atactttttt agacatgatg tgtctccttt ttcttaaaat
     8521 ttcgagaact ctctcgttgt tataaaatat attacaacaa aacaaaagaa cttgcaagaa
     8581 atttgctcag agtttatttg aaaattgtaa aatttcggaa actctaatca tttgtgactg
     8641 aaaaagtaag aactgtttca ctttcaaaat cggttttgtt tgaagggaga aatagaattg
     8701 gttgctcaaa gcacagcttt gaggttgcag ataaagctga cgtggtttga agagattttc
     8761 gaagagtatt cttatattca cttgtaataa agcttaatag atggtaaaat agacgagtga
     8821 aaaaaagaca aaacaaagca aaaaataatc tactgtggca gtatggtcta gggatgacga
     8881 ttttgtttgt ggttatcagt ggttcctttc tgtatatggt ttctcttagc atgaaaccct
     8941 atcaaacagc taaaagtgaa ggagaaaaat tagctcagca gtatgcagga ttagagcagg
     9001 tcgatcaggt tgatttatac aatggcttgg aatcttatta cagcgttctt ggtcgtaata
     9061 aacagcaaga agcgcttgct gtcctgattg gtaaagatga ccataagatt tacgtttatc
     9121 agctaaatca gggtgtttca caagaaaaag cagaaacggt ttctaaggaa aagggagctg
     9181 gcgagattga caagataacc tttggccgtt atcaagataa gccaatctgg gaagttaagt
     9241 caggatctga tttttatcta gtagattttg aaacaggagc attggtcaac aaggagggcc
     9301 tatgaaacta tccaaccgtg ttttagaaat ggaagaaagt gtgactttgg ctgctggagc
     9361 ccgtgccaaa gcactgaagg ctgagggtag agatattttg tctctaacct tgggtgagcc
     9421 agatttcact actcccaaaa atatccaaga tgccgccatt gcatcgattc gagatgggcg
     9481 tgcttctttt tatacagtaa cctcaggtct gccagagctt aaggcggcgg tcaatagcta
     9541 ctttgagcgc ttttacggct attctgtagc gtcaaatcaa gtgacagtcg ctgcgggagc
     9601 caaatattct ctctatacct tctttatggc tgtggtcaat ccaggtgatg aagtcatcat
     9661 cccaacccca tactgggtta gctatggaga tcaggtcaag atggcagaag gcgttcccgt
     9721 ctttgtttct actaaggaag acaatcactt taaggtgacc gtagatcagt tagaagcagc
     9781 tcgcactgac aagaccaagg ttttggtgct gaattcgcca tctaatccca caggtatgat
     9841 ttacacccgt gaggaactct tggcaattgg aaactgggct gtagaaaatg atattctcat
     9901 cctagcagat gatatctatg gccgcttggt ttataatggt catgagttca caccgatttc
     9961 tagcctatcg gaagcgattc gcaagcaaac agtggtcatc aatggtgtgt ctaaaaccta
    10021 tgccatgact ggttggcgga ttggttatgc cgttggagaa gcagatatta tcgctgccat
    10081 gtccaagatt gcaggtcaaa caacttcgaa tccgtcagca gtagcccaat atgcagcagt
    10141 tgaggctcta tcaggtgagc aagatactgt agaaagcatg cgtcaggcct ttgaggaacg
    10201 tcttaatacc atctatcccc tccttgcaga ggtaccagga tttgaagtgg tcaaaccgca
    10261 aggggccttc tatctcttcc caaatgtcaa aaaggccatg gagatgaaag gctacacgga
    10321 tgtgacagac tttacaactg ctatcttaga agaagccgaa gtggccttgg taacaggagc
    10381 tggatttgga gcaccagaaa atgtccgcct cagctatgcg acagacctag acacgcttaa
    10441 agaagcagtc gaacgcttga aagcatttat gggtagtgag aatgattgat cattttgaga
    10501 ttaaggtaaa ggatttacaa atttcagaag gattttatag gagttttctc gctcctttgg
    10561 actataaatt ggcttttaag actagttctc taattagttt tctatccccg aacagccctc
    10621 atcctggtgg tgatttttgg ctgactcagg gaacacaaga tcctgttcat tttgcttttt
    10681 tagcagaaaa taaggaagaa gttcaggctt gttatgaggc tggcttagag gcaggtgggc
    10741 gagacaatgg ggctcctggt tatcgaagtg agcatccgat ttactatgct gcttttatga
    10801 ttgacctgga tgggaacaat atagaggtgg tttgccataa agaataaaaa agaaaaggaa
    10861 aaataatgac aaaacgtgta acgattattg acgtaaaaga ctatgttggt caggaagtga
    10921 cgattggcgc ttgggttgcc aacaaatcag gaaaaggaaa aatcgctttc ttacaattgc
    10981 gtgatggaac agccttcttt caaggtgtgg cttttaaacc aaactttgtc gaaaaatttg
    11041 gtgaagaagt gggacttgag aagtttgatg ttatcaaacg cttgagccaa gaaacgtctg
    11101 tttatgtgac aggtattgtc aaagaggacg aacgttctaa atttggctat gagttggaca
    11161 tcacagacat cgaagtgatc ggtgaatctc aagactaccc aatcacacca aaagaacacg
    11221 gaacagactt tttgatggat aaccgtcact tgtggctacg ctctcgtaag caagtagctg
    11281 tgttgcaaat ccgtaacgct attatctatg caacttatga gttctttgac aagaacggtt
    11341 ttatgaagtt tgacagccca attctttcag gaaatgcggc agaagattct acagaactct
    11401 ttgaaactga ctacttcgga acgccagcct acttgagcca atcaggtcag ctttacctag
    11461 aagcaggggc tatggctctt ggtcgtgtct ttgactttgg tccagttttc cgtgctgaaa
    11521 aatcaaaaac acgccgtcac ttgactgagt tctggatgat ggatgctgag tactcatact
    11581 tgacacatga tgagtcgctt gacttgcaag aagcttatgt gaaagctctt ctacaaggtg
    11641 ttcttgaccg cgcgcctcaa gccttggaaa ccttggaacg tgatacagaa ctcttgaaac
    11701 gctacattgc agagccattc aaacgtatca cttacgatca agccattgac ctcttgcaag
    11761 agcatgaaaa tgatgaagat gctgactacg agcatcttga gcatggtgat gactttgggt
    11821 caccacacga aacttggatt tcaaaccact ttggtgtgcc aacatttgtc atgaactatc
    11881 cagcagccat caaggccttc tacatgaaac cagttcctgg aaatccagag cgcgtgcttt
    11941 gtgcagactt gcttgctcca gaaggctatg gagaaattat cggtgggtct atgcgtgagg
    12001 aagattacga tgcccttgtc gctaagatgg atgaacttgg catggatcgt acagaatatg
    12061 aattctacct tgaccttcgt aaatacggta cagttccaca cggaggattt ggtatcggta
    12121 tcgaacgtat ggtaaccttc gcagcaggaa caaaacatat ccgtgaagct attccattcc
    12181 cacgtatgtt gcaccgtatc aaaccataag aacaggaaaa cgcccatgtg gcgttttttc
    12241 gaattctagt gtttttactt gcgtaaaaaa attttttcta gtataatagt ttattgtgag
    12301 cgaacctcac ttaccccttg caaagtcttg gggtcattag accaaaagga ggaacatatc
    12361 aatggctaaa tacgaaattc tttatatcat tcgtccaaac attgaagaag aagctaaaaa
    12421 cgctttggta gcacgttttg actctatttt gactgacaac ggtgcaactg ttgttgaatc
    12481 aaaaacttgg gaaaaacgtc gtcttgcata cgaaatccaa gatttccgtg aaggacttta
    12541 ccacatcgtt aacgttgaag caaatgacga tgcagctctt aaagagtttg accgtctttc
    12601 aaaaatcaac gctgacattc ttcgtcacat gatcgtcaaa attgacgcgt aagaaggtaa
    12661 actatgatta acaatgttgt acttgtaggg cgtatgacac gtgacgctga gttgcgttat
    12721 accccatcaa atgtagcagt tgcgactttt actcttgcag taaaccgtac atttaagagt
    12781 caaaatggtg aacgtgaggc tgattttatc aatgtcgtta tgtggcgcca acaggctgaa
    12841 aatcttgcta actgggctaa aaaaggctca cttatcgggg tgacaggtcg tatccagact
    12901 cgtagttacg ataaccagca aggacaacgt gtctacgtga cagaggtcgt ggctgagaat
    12961 ttccaaatgt tggaaagccg tagtgtgcgt gagggccaca caggtggagc ttactctgca
    13021 ccaactgcaa actattcagc acctacaaat tcagtaccag acttttcacg taatgaaaat
    13081 ccatttggag caacaaaccc attggatatt tcagatgatg atttaccatt ctaatggaca
    13141 actaaactta taaaggagaa aaaacatggc tcaacaacgt cgtggcggat tcaaacgccg
    13201 taaaaaagtt gattacatcg cagcaaacaa aattgaatat gttgattaca aagatactga
    13261 gcttcttagc cgtttcgttt cagaacgtgg gaaaatcctt cctcgtcgtg taacaggaac
    13321 ttcagctaaa aaccaacgta aagtaacaac agctatcaaa cgcgctcgcg taatggcttt
    13381 gatgcctttc gtaaacgaag attaaagaaa agacccggtt gggtctcttt ttcatgagct
    13441 tgaaaacaag aaagcgaatt aagaccccaa cgggtctttt ttcacaagct ttgaaatgag
    13501 agagcgagtt aggctcagtg gctccctttt tacgagtttg aaaacaagag aacacattaa
    13561 aagcacgatg gagctttttc ataaatatgt cttttttctc atccaagaaa ttaaaataaa
    13621 aatgataaac tttttgaaaa taggggattt gcctacttta tgatataatg gaaagagtta
    13681 gattgaaaga ggtagtgaga tggacgcgaa attaagatac aaggcaaaga agatcaagat
    13741 tgtctttttt gatattgatg atacattgcg gaattcaaag acagggttta ttccaactac
    13801 aattcccact gtttttaaac agttgcgtga aaaaggaatt ttaacaggaa tcgcctctgg
    13861 acgtggcatt tttggtgttg ttccagagat tcgtgatctc aagcctgact tttttgtaac
    13921 tttgaatgga gcttatatcg aagataaaaa aggtcaggtc atttatcagc atcagattga
    13981 aaagtcagat gttgaggagt atatctcttg ggctaagcaa gaaggaattg agtatggctt
    14041 ggttgggagt catgatgcca agttgtcgac tcgcaccgat atgatgagtg aagctatcaa
    14101 tccaatttat cccgacttag atgtagatcc cgatttccat gaaaaagaag atatctatca
    14161 gatgtggact tttgaagata agggagatga cttgcacttg cctgacagtc tctcagacaa
    14221 acttcgcatg gttcgttggc atcaacattc gtctgatatt gtgccgattt caggctccaa
    14281 agcgacgggg gtggaaaagg ttgtggaaca ccttggcttg aaaccagaga aggtcatggt
    14341 ttttggagat ggtctcaacg acttggaact ctttgattat gctggaatca gcgttgccat
    14401 gggaatttct catgataaaa tcaaagaaaa agcagattat attacaaaaa cattagaaga
    14461 agatggcatt tttgatgcct tagaagtatt tggtatggta gaaaaagaat tgcattttcc
    14521 acaagtagac attgaaacag tagaaggtcc tcttgcgact attaagacca atcacggaga
    14581 cttacgtatc aagcttttcc ctgaacatgc tcctaaaaca gtggctaact ttgtatctct
    14641 ttcaaaagat ggctactatg atggtgtcat tttccaccgt attatcaagg actttatgat
    14701 ccaaggtgga gacccaactg gaactggtat gggtggcgag tcaatctacg gcgaatcttt
    14761 tgaggatgaa ttctcagaag agctttacaa tatccgtggt gctctttcca tggcaaatgc
    14821 tggtccaaat accaacggca gccagttctt tatcgtgcaa aaccaacacc taccttattc
    14881 gaagaaagaa attactcgtg gtggttggcc agaaccgatt gcagaaatct atgccaatca
    14941 aggtgggaca cctcacctag accgccgtca cacggttttt ggtcagttag ctgatgaagc
    15001 atcttacgct gtcttggatg ccattgctgc tgttgagaca ggagctatgg acaagccagt
    15061 tgaagatgtt gtaattgaaa ctattgaaat cgaggactaa gatgaaaatc ggtgataagc
    15121 taaaggggcg tattacaggg attcagccct acggtgcctt tgttgagtta gagacgggtg
    15181 atacggggct gattcacatt tcagaaattc ggacaggatt tattgaaaat attcatgaaa
    15241 ccttgaaagt cgatgaagag gttcaagttc aggtagtgga tttagatgaa tttacgggga
    15301 aagccagtct ttctatccgc actttggagg aagaaaagta ccagtttcct agacggagac
    15361 gcttttcaag cgaccgcttt aactacggtt ttgctccctt tcgacgaatg ctaccaatct
    15421 ggactggaga agccctgcac catttaaaaa agaagaagta gtttagagtt ttatattttt
    15481 tgtaatgtta atatgaattt gctataatag gaccatggaa gaagaacaat tattaaaatc
    15541 aggagagcgc attaaccagc tcttttcgac agatatcaaa atcattcaaa atagagaggt
    15601 ttttagctat tcggtggata gtgttctctt atcacgattt ccacgttttc ctaagaaggg
    15661 gttgattgtg gatttctgtg ctgggaatgg agcagtgggg ctttttgcta gcactcgtac
    15721 tcaagcacag atattgtctg ttgagattca ggagcgtttg gcggatatgg ctgaacgctc
    15781 tgtccgtttg aatggattag aggagcaaat gcaggtcatc tgcgatgatt tgaaaaatat
    15841 gcctgctcac attcagggga gtaaggtgga tatgattttg tgtaatccac cctatttcaa
    15901 ggtgaatcct tattctaatc tgaacgagag tgaacattat ctcttggctc gacacgaaat
    15961 cacgactaat ttggaagaaa tctgtcgtag tgcccagagt attctcaagt ctaatgggcg
    16021 tttggccatg gttcatcgtc ctgatcgact tctggatatt ttggatacgt taaaacgaca
    16081 taatctagcc cctaagcgcc tgcagtttgt ttatccaaaa agagaaaagg aagccaatat
    16141 gcttttgatt gaggcgatca aggatggctc aacaagtggc tttaaggtct tacctccttt
    16201 gattgtccac aatgatgatg gctcttatac gcccgaaatc gaagagattt attatggatc
    16261 ataaggctta tatgtacgtt ctggagtgtc gtgatggatc ctactatata ggctatacga
    16321 ctgatatgag aagatgcctc gctatccaca atagtgggaa gggagccaaa tatacacgag
    16381 cacgcttgcc agtcaaactt atctatgctc aaggttttgc cagtaaggaa gaagccatgt
    16441 cggctgaagc tcttctcaag cgtaagaaga ggccacagaa ggaagaattt ttatctgaaa
    16501 atcaagatag aaatttactc agttattttg aagaatcgtg gggagtcctt tgactcctct
    16561 tacctttgtc aaaaagcgaa aaaaatgcta caataaagaa aataaacaaa atgaggtatt
    16621 atcatgtcca agattctagt atttggtcac caaaatccag actcagatgc catcggatca
    16681 tctgtagctt ttgcctacct tgcaaaagaa gcttacggtt tggatacgga agctgttgcc
    16741 cttggaactc caaatgaaga aacagccttt gtcttgaact attttggtgt ggaagcacca
    16801 cgtgttatca cttctgccaa agcagagggg gcagagcaag ttatcttgac tgaccacaat
    16861 gaattccaac aatctgtatc agatatcgct gaagtagaag tttacggtgt tgtagaccac
    16921 caccgtgtgg ctaactttga aactgcaagc ccactttaca tgcgtttgga gccagttgga
    16981 tcagcgtctt caatcgttta ccgtatgttc aaagaacatg gtgtagctgt gcctaaagag
    17041 attgcaggtt tgatgctttc aggtttgatt tcagataccc ttcttttgaa atcaccaaca
    17101 acacacccaa cagataaaat cattgctcct gaattggctg aattggctgg tgtgaacttg
    17161 gaagaatatg gtttggcaat gttgaaagct ggtaccaact tggctagcaa atctgctgaa
    17221 gaattgattg atatcgatgc taagactttt gaactcaacg gaaataatgt ccgtgttgcc
    17281 caagtgaaca cagttgacat cgctgaagtt ttggaacgcc aagcagaaat tgaagctgca
    17341 atgcaagctg ccaacgaatc aaacggctac tctgactttg tcttgatgat tacagatatc
    17401 gtcaactcaa actcagaaat cttggctctt ggtgccaata tggacaaggt cgaagcggct
    17461 ttcaacttca aacttgaaaa caatcatgcc ttccttgctg gtgccgtttc acgtaagaaa
    17521 caagtggtac ctcaattgac tgaaagcttt aatgcgtaag attttgggtg tcagctcaaa
    17581 atcggaaagt ctagtttgcc ttatatcgaa aggagtttcg gctccttttt tctaggagtg
    17641 aagtatgtta gaaaatggcg atttgatttt tgtgagagat gggtcagaca tgggacaggc
    17701 catccagact tccacaggta actatagcca tgttgccatt tatttggatg ggatgattta
    17761 tcatgctagt ggacaggctg gtgttgtctg tcaagaaccg gcagacttct ttgagtccaa
    17821 tcatttatac gacctctatg tttacccaga aatggatatc cagtcggtga aggaaagagc
    17881 ttgcaaacat cttggagcac cctacaatgc ttctttctat ccagatgcac ctggtttcta
    17941 ctgctcccag tatatagcag aaatcctacc tatttttgaa actattccta tgaaatttgg
    18001 agatggggag caggagatta gtgatttttg gagggagtat tacatagaac taggtctgcc
    18061 tgttcctctg aaccaagctg gtaccaatcc tagtcagttg gcagcatcgc ctctgttaca
    18121 atgtaaagaa aggaatcttc atgattcaga tttttaatcc atctcgtttg acgagacagc
    18181 catttttgga gaattgatcc gctatctgga ccagtatgag gatgtgattc tacgggaaat
    18241 taaggctcaa tttccagatg ttgcagttga taaactcatg gaagagtata taaaggcagg
    18301 cttgattcta cgtgaaaata agcgctatta cctcaatttt cctacgcttg aatcacttga
    18361 tagtcttgaa ctggatcaag agatttttgt cagagaagct agtccggtct atcaagcctt
    18421 gttggagcag agttttgaga cggaattgcg caatcaaatc aatgcagcta ttttagttga
    18481 aaagacggac tttgcgcgca ttaaaatgac tctgtccaat tatttttaca aggtcaaaca
    18541 gcagtatcct ttgacagaaa aacagcagga gctctatgac attttaggag atgttaatcc
    18601 tgagtatgca ctcaagtata tgacggcttt tttgttgaaa tttctcaaaa aagaccagct
    18661 tatgcagaaa tgccgtgata tctttgtgga cagtttggtt gtcttaggct atattgtgca
    18721 aaatgaagat ggaaagtatg agttggctat cgattttgat aaggagagat taactttcta
    18781 cttagcgtga tttcttgttt ctgagtacat tgtttgactt tccttagtat tcggtataaa
    18841 ctatatgtaa ccggtaacac atatcggaat aaactaaagg agacaatcat atgtcacttg
    18901 aaaacaaatt ggaacaagca acaggcgctg tcaaagaagg ttttggtaaa gttactggag
    18961 acagcaagac agaacttgaa ggagctgttg aaaaaacagt tgctaaggca aaagacgttg
    19021 tagaagacgc aaaaggtgct gtagaaggtg ctgtagaagg tgccgttgaa ggtttgaaaa
    19081 acgtttttac taaagaatag gaaaaaatca agggtttcat tttcccttga ttttttctat
    19141 tcttataaat aattttctgc gacggctgta tctcctgggt aggattcttt cttgccctgg
    19201 atgatttggt aacaatcggc tcccttaccc gcaataataa ctgcatctaa ttcgtgattt
    19261 gtgatagcca ttgccgcctt gatggcttct tggcgatccg caatcttctc aacaggatga
    19321 ttgatgtagc tactaatttc atctgcaatg gccattgggt cttcatagtt agggtcatca
    19381 gcagtcagaa agacttgaat ctcagggtgt tgattgagga ggaggccaaa gtccttacga
    19441 cgactttctc ccttgtttcc tgttgatccc agaaccagag caatctttcc ggtttgatga
    19501 gtttcaacca cattgatgag ttttttcaga ctatccccat tgtgggcata gtcgatgaag
    19561 accttggctc catttttctg agtgaggact tccatacgac caggaacgcg ggttgcagcg
    19621 atgccttttt tgatgtcctc aagacttgct ccgagacgga gacaagcaag tccagcagca
    19681 actgcatttt cttggttgaa gttgccaatg agttggatat cataatctcc agcgagttta
    19741 cccgtagctg aaaagctaaa ggctttggaa ttctcgattt ggttatcaaa ttggctacca
    19801 tagaaatcat ggtcttgatc tttaacctgt tctttcaaga ctgagaagtg gtccatgtca
    19861 ctgttaatga tgactgctcg gctattttcc atcaagagac gcttgtggta gaaatagtct
    19921 tcaaagctag ggtgttcaat cgggccgata tggtctgggc tgatattgag gaaaactccc
    19981 acatcaaagg ttagaccata gacacgtctg accagatagg attgactgga gacttccatg
    20041 atgaggtggg tacggtcatt ttgcacagcc tgattcatca tgtcaaagag gtcaatactc
    20101 tcaggggttg tcaacgctga cttaaagaaa gtctcgccat caagagttgt gttcatggtc
    20161 gacaacatag caggtcgatg cccttgagat aagatgttat aggcgaaata ggctgctgtt
    20221 gtcttaccct tagtaccagt aaaggcaagg agtttgagtt tttcctgtgg attaccatag
    20281 aactccatgg caatcaaact catggctttc tttatatcgt tcacaatgat gacagggata
    20341 ccgacttcgt agtccttttc agctacatac caagctaagc cttgtgttat agcagaaaga
    20401 aggtattctt ttttaaaggc agcgcctttt gcaaaaaaaa gagtgtcttc tgttactttt
    20461 cggctgtcgt agctgatgct atcaaaaaca actttgctgt agttgtagtg gtaatgacct
    20521 tggtcaataa tttcgcgaaa aaggccatct ttctttaaaa tatctaatac agtttcaatt
    20581 tttatcatac tttctattgt aaaccgaaag tcgcaaattt acaagtaaca aggaaaagtt
    20641 tataatggaa gataaggagt ttttcctagt tatcaaaatt gaatgaggaa tctatgtcgc
    20701 acgaaaacaa tcaccagcag gcccagatgt tacgggggac tgcttggcta acggctagta
    20761 actttatcag tcgcctactc ggggctgttt acattatccc ttggtacatc tggatggggg
    20821 cttatgcagc taaggcaaat ggtctcttta ccatgggtta caatatctat gcttggttct
    20881 tgttggtttc aacagcgggg attccagttg cggtggccaa gcaagttgcc aagtataata
    20941 ccatgcgaga agaagagcat agctttgccc tgattcggag cttcttaggc tttatgacag
    21001 gactaggcct ggtttttgct ttagtcttgt atgtctttgc tccttggcta gcagacttgt
    21061 ctggcgtggg caaagacttg atcccaatca tgcaaagctt ggcttgggga gtcttgattt
    21121 tcccgtctat gagtgttatc cgaggatttt tccaagggat gaataacctc aaaccctatg
    21181 ccatgagcca aattgctgag caggtcattc gtgttatctg gatgctccta gcaaccttta
    21241 tcattatgaa gctcggttca ggagattatc tagcagccgt tacccaatca acctttgctg
    21301 cctttgtcgg tatggtagcc agttttgcag tcttgattta tttccttgcc caagaaggtt
    21361 cactcaaaag agtctttgaa acagaagata agattaacag taagcgtctc ttggttgata
    21421 ccattaagga agccattcct tttatcctga cagggtctgc catccagctc ttccagattt
    21481 tggatcagct gacctttatc aatagtatga gctggtttac caactacagc aatgaggact
    21541 tggttgtcat gttttcttat ttctcagcca atcctaataa aatcacgatg attttgattt
    21601 ctgtaggggt ttcgattggg agtgttggtt tgccactttt gacggaaaac tatgtcaagg
    21661 gggacttgaa agcagcttct cgtctggttc aggacagtct caccctactc tttatgttct
    21721 tgctaccagc aacggttgga gtggttatgg taggagaacc tctatataca gtcttctatg
    21781 gtaagccaga tagtttggct ctgggcttat ttgtctttgc agttttgcag tctattattt
    21841 taggcttgta catggtcttg tctccaatgc ttcaggccat gttccgcaac cgcaaggccg
    21901 ttctctattt tatctatggt tctattgcca agctagtctt gcaactacct accatcgccc
    21961 tcttccacag ttatggtcct ttgatttcaa caaccattgc tctcatcatt cctaacgtct
    22021 tgatgtatcg ggatatttgt aaagtaactg gtgtcaagcg caaggtgatt ttgaagcgaa
    22081 ccattttaat cagtttgctg accctagtca tgtttctgtt aataggaacc atccagtggc
    22141 tgttaggatt tttcttccaa ccaagtggac gtttgtggag cttcttttat gtagctcttg
    22201 tcggtgccat ggggggtgga ctttatatgg ttatgagtct gcgtacctat ttattagata
    22261 aggtaatagg aaaagcccaa gcagatcgcc tgcgagcaaa atttaagctt tcgtaaggta
    22321 gcatttataa ataaaaggaa taagttgaac aatcttttag gagaacttga agcttattcc
    22381 ttttttagcg taaaaatagc taaaattata tttcaaaaat agaaaatgag gcttttttcg
    22441 attttttgga aaaaatcatt gactaaacaa actaaacgtt gtataataaa acaaatattt
    22501 aaagcaggag gttccggaaa tgaaaaagtc taagagcaaa tatctaacct tggcaggtct
    22561 tgtcctgggt acaggagttt tattgagcgc gtgtggaaat tctagcacgg cgtcaaaaac
    22621 atacaactat gtttattcaa gtgatccatc tagcttgaac tatctagcag aaaaccgcgc
    22681 agcaacatcc gatattgttg caaatttggt agacgggtta ttagaaaatg accaatatgg
    22741 gaatattatt ccatcattag cagaggattg gactgtttct caggacggtt tgacctatac
    22801 ctacaaactt cgtaaggatg ccaagtggtt tacttctgag ggagaagaat atgcgcctgt
    22861 aactgcccag gattttgtga caggtttgca atatgcagct gataaaaaat cagaagcctt
    22921 gtatctagtg caggactctg ttgctggttt ggatgactat atcactggta aaacaagcga
    22981 cttttcaact gtcggtgtca aggcacttga tgaccaaacg gttcaatata ctttggttaa
    23041 accagaactt tactggaatt caaaaacact tgcaacgata ctttttcctg ttaatgcaga
    23101 tttcctgaaa tcaaaagggg atgattttgg gaaggcggat ccatctagta ttttgtacaa
    23161 tggacctttc ttgatgaaag cacttgtctc aaaatctgct attgaatata agaaaaaccc
    23221 taattactgg gatgctaaga atgtctttgt agacgatgtg aaattgacct actatgatgg
    23281 tagcgaccaa gaatcactgg aacgtaattt tacagctggt gcttatacta cggctcgtct
    23341 ttttcctaac agctccagct atgaagggat taaagaaaaa tacaaaaaca atatcatcta
    23401 tagtatgcaa aattcaactt catatttctt taattttaac ctagatagga agtcttacaa
    23461 ttatacttct aaaacaagtg acattgaaaa gaaatcgacc caggaagcag ttctcaataa
    23521 aaacttccgt caggctatca attttgcttt tgacagaaca tcttatgggg ctcagtctga
    23581 agggaaagaa ggtgcaacaa agattttgcg taacctagtg gttcctccaa actttgtcag
    23641 tatcaaggga aaagactttg gtgaagttgt agcctctaag atggtcaact atggtaagga
    23701 atggcaaggt atcaactttg cggatggtca agacccttac tacaatcctg agaaagccaa
    23761 ggctaagttt gcggaagcta agaaagaact cgaagcaaag ggtgttcaat tcccaatcca
    23821 cttggataag actgtggaag taacagataa agtaggcata caaggagtta gttctatcaa
    23881 acaatcaatt gaatctgttt taggttctga taatgtagtg attgacattc agcaattaac
    23941 atcagatgag tttgacagtt caggctactt tgctcaaaca gctgctcaga aagactatga
    24001 tttatatcat ggcggttggg gacctgatta tcaagacccg tcaacctatc tcgatatttt
    24061 taatactaat agtggaggag ttctacaaaa tcttggacta gagcctggag aagccaatga
    24121 caaggctaag gcagttggac tggatgtcta tactcaaatg ttggaagaag ctaataaaga
    24181 gcaagatcca gccaaacgtt atgagaaata tgctgatatt caagcttggt tgattgatag
    24241 ttctttagtt cttccaagtg tttcgcgtgg gggaacacca tcattgagaa gaaccgtacc
    24301 atttgctgct gcctatggtt taaccggtac aaaaggggtt gaatcatata aatacctcaa
    24361 agtacaagat aagattgtca caacagacga atatgcaaaa gccagagaaa aatggttgaa
    24421 agaaaaagaa gaatccaata aaaaagccca agaagaattg gcaaaacatg tcaaataaaa
    24481 tctaattgta gataagtttg tgtaagaagt ctttgtgctt aaaaacgcat aatatcaggt
    24541 atataaaatc ctagatgtta tgcgttttgt tataggaaga tttattagat tttatcctca
    24601 aattgagtta ttcccgactt tatccgttga aatattataa ggagtattta tgaaattaaa
    24661 attattaaga gtagatacta aggtgattat ggggagtttc ttacttgttc tgtctagtct
    24721 acttgctttg ttgcttcccc ttatcttaaa gggtttaata gatgggagtt ctattgaaaa
    24781 tataggttcc aaagtatttc aatcgttttt gatttttatt ggtcaagcct tgttttcttc
    24841 tattggttac tatctgttta gtcaatcggg tgaaaaaaag atagcaaaaa tcaggaaaaa
    24901 agtgatagag gggttgattt atgcagagaa atccttcttt gataagagcc aaagtgggga
    24961 gttgacttct gccattgtca atgacatgag tgtcattcgt gagtttttaa ttacgacttt
    25021 cccaaatatt attctgagtt tagttatggt acttggttcc attgtagtct tatttagtct
    25081 tgattggaat ctttctctac ttttattcat cactcttcct tgtatgatgt ttattatctt
    25141 gcccctttcc aatatcagtg aaaagtatag tcgtcgttta caggaggaaa tcggattttt
    25201 aacagggcaa ttgactgaaa agattcaaga acatgaatta attaagacta accaagcaga
    25261 gaaaagtgta caggatgttt tggataattg tattgaaagg gtacaaaaca attcactgaa
    25321 atcagatagg gttacttctt ttgagacccc gtttgctctc ttatttatct ttgcgactat
    25381 agttgtgatg ctaacctatg ggggttatcg ggtcagcgca ggatatatat ctgtgggaac
    25441 cttggtttcg tttttgattt acctctttca attacttaat cctattagta atatagctaa
    25501 ttttgtaact atttattcta gtagcaaggg atcttcagtt gcactggaga acttgcttgc
    25561 agttcctaaa gaaaaatttg agggaggaaa atcggtatca ggacaagggt tgaattttaa
    25621 ccatgtctat tttggttatg atgaaaatcg acctgtctta aaggatatta cttgttcaat
    25681 tttcaagggg caaaaaattg cttttgttgg gccatctgga tcaggaaaat caacgattgt
    25741 gcgtttgtta gagcggtttt ataaaccgct ttcaggagat attctaatgg agcaatcaag
    25801 tatatatgat tttaacttaa aagaatggag aagtaaaatc gcttgggttt cacaaaataa
    25861 tgcagtctta tctggcagta ttcgtgacaa tctttgtctc ggtttgaatc gcttagtaac
    25921 tgatgatgaa ttgatgaaag tgctagactt agtatcacta ggtgatgaga ttcgctccat
    25981 gaaagaggga ctagatactg aagttggtga acgcggacga ctcttgtcag gggggcgaag
    26041 ccaaagactt caaatagcta gagcctactt aaaagatgct gaaattctta tatttgatga
    26101 agccactgct aatcttgatg cggattctga gtatgcgatt atcagtagcc tctattctgt
    26161 actaaaggag aagacggttg tgattatagc gcatcgcttg tcaacggtaa aagatgtgga
    26221 ttgtattttc ttcttagagg aggggaaaat cactggctca ggaactcata aggaactact
    26281 ggaaaatcat gagcgttatg ctcgttttgt gcaggagcaa atgatagagt gaaggtgtct
    26341 tttgagattc accattttat agtctattaa agggagcagg aaaaactccc tttttatata
    26401 gtttgaaact ataactagct cttgaaaaga agaaaatgag ttgatgaaaa taagtggtac
    26461 aatagttact atagatttgg aggaattgta tgagcaagga attacacatt aacacaattt
    26521 tagcacaagc agggatcaag tctgatgagg caacaggtgc tttggtgaca ccacttcatt
    26581 tttcaacgac ctatcagcat ccagagtttg gtcgatctac tgggtttgac tatacgcgca
    26641 ctaaaaatcc aactcgtagt aaggctgagg aagtcttggc ggctattgag tcagcagact
    26701 atgccctagc gactagctca gggatgtcag ctattgtact ggcctttagc gtctttccag
    26761 taggaagtaa ggtcttggca gtgcgtgatc tttacggtgg ttcttttcgc tggtttaacc
    26821 aagtggagca ggaaggtcat ttccatttta cctatgccaa tacagaagaa gagttgattg
    26881 ccgagttaga aaaggatgtg gatgttctct atatcgaaac cccaaccaat cccttgatgt
    26941 tggaatttga tatcgaaaaa ctagcaaaat tggctcatgc taagggtgcc aaagtggtgg
    27001 tggacaatac cttctatagc cctatctacc aacgtccgat tgaagatgga gcagatatcg
    27061 ttctccattc agcaaccaag tatctagcag gccacaatga tgtcttggct ggagtggttg
    27121 tgaccaatag tttagaacta tacgagaagc ttttttacaa tcttaataca acaggggcag
    27181 tcttgtctcc atttgacagc taccagttgc ttcgtggtct caagaccttg tctcttcgta
    27241 tggagcgctc aacagctaac gcccaagaag tggttgcctt tttgaaggat tctccagcag
    27301 ttaaggaagt tctctacact ggtcgtggag gcatgatttc ctttaaagta gccgatgaaa
    27361 cacgcattcc tcatattttg aacagtctca aggtcttctc ttttgcggaa agtttgggtg
    27421 gagtggaaag tcttattact tatccaacga ctcaaactca tgctgatatt ccagcagaag
    27481 tacgccattc ttatggtttg acagatgacc tcttgcgttt gtctattggg attgaggatg
    27541 ctagagattt gattgcagat ttgcgccaag ccttagaagg ataagacaaa gatgggaaaa
    27601 tatgatttta caagcctgcc caaccgttta gggcaccata cctataaatg gaaagaaaca
    27661 gaaacggata gtgaagttct accagcttgg atagcggata tggactttgt agtcttgcct
    27721 gaaatccacc aagccgtgca aacttacgca gaccaactgg tttatggtta tacctatgcc
    27781 agtgaagact taattaagga agttcaaaag tgggaagcta cacaatacgg ttacaacttt
    27841 gacaaagagg ctcttgtctt tatcgagggt gtggtaccag ccatctcaac agctattcaa
    27901 acctttacaa aagaaggcga ggcggtttta attaacacgc ctgtctaccc gccctttgct
    27961 cgcagtgtca agttgaataa tcgtagattg attactaatt ccttagtgga aaaggatagt
    28021 ctgtttgaga ttgactttga ccaacttgaa aaggatttgg tggaagagga ggttaaactc
    28081 tatgttcttt gcaaccctca caatcctggt ggacgtgttt gggaaaaaga agtgttggag
    28141 aagattggcc aactctgcca aaaacacggt gttttgttag tttcggatga gattcaccaa
    28201 gatttgaccc tctttggtca caaacaccag tctttcaata ccatcaatcc tgccttcaaa
    28261 aattttgcta tcgtcttgag cagtgccact aaaacattta atattgctgg aacaaaaaat
    28321 tcctatgcag tcattgaaaa tcctaagttg agactggctt tccagaaacg cctgttggcc
    28381 aataatcagc atgaaatttc aggcttgggt tatttggcga cagaagctgc ctatcgatac
    28441 ggtaaagatt ggctagagga actcaagcaa gtctttgaag accacatcaa ttatgtggtg
    28501 gatctatttg gaaaagagac taaaatcaag gtcatgaaac cgcaaggtac ctacttgatt
    28561 tggcttgact tttcagctta tgacctgact gatgaaacat tgcaagagtt gttgagaaat
    28621 gaagccaagg ttatcctcaa ccgtggtttg gattttggag aggaaggaag tctccatgcc
    28681 cgcatcaata tagctatgcc caaatctctg ttgcaagaag tctgtcagcg gattgtggct
    28741 acttttgcca aatgttaaaa atccagcctt ctaggagaaa agtcttccta gaaggctatt
    28801 ttcataggcg aaaatatggt ataataaaaa gataaggtaa aggtgaaaat atggctaaat
    28861 tgattccggg gaaaattcgt atcgaaggtg ttgcccttta tgaaactggt aaggttgata
    28921 tcatcaagga aaagaacaat cggctctacg ctcgcgttgc agaagaagaa ctgcgctata
    28981 gtttagagga tgatttgatt ttttgtgcct gtgatttttt tcaaaagagg ggctactgtg
    29041 tgcatttggc agcgctagag cattttctga aaaatgatga gcgtggtcag gaaatcttgt
    29101 ggagtctgga agaaggtcat gaagaaaaag aggccgttga aaccaaggtg accttgggtg
    29161 gcaagttttt ggatcgaatt ttatctccaa aatcagaatg cgcctatgag ttatcagctg
    29221 tgggtcaggt ggaagcagga accaatcata tcttgtggac tctgagaatc ggccaaatca
    29281 atagccaaaa atactatgtc attcgggata ttccactttt tttaaggatt gtcgagcaga
    29341 gaaagtcgta tatgattggc aagatttatg aggagtctct ttcttgggaa gcctttgatg
    29401 atgccagcca agaacttttg actttcttgc acggactaac ggaggaaggg ctggttccag
    29461 acctcttttt ccaaaaccaa ggtcggcacc tctttttccc tctgaccttt tttgagcagg
    29521 gtgtgaattt actgatggcc ttgccccatt ttcaatttga ccatcaagtg gatagctacc
    29581 aaaccctgct ttttcaggat atgcatgctg atgccaatct atttgccttt acagtaacag
    29641 aatattcgga ctattttgaa atggaaatca gtgagagtcc tagggtcaat gtcttttatc
    29701 aaggagcagt acttttccat aaaggtcagg tttatttttt aacagaccag cagatgcgtc
    29761 ttctcaagga aattaaagcg ttacctgtgg atcgacaagg aaagaaatac ctgcaatttg
    29821 atagcagtga tcgagacaaa ttggcctcct gtctgactct ttttatccag atgggcaccg
    29881 tttcagctcc agaacgtcta caaatcaaaa cttttgcgcc ctctttttac tttgacaggg
    29941 aagaagataa tcggattcgt ttagaaattc agtttgatta tggaaataga caggtatcta
    30001 gccgacaaga gctagaagaa ttaccatttt caagtgacgc ggacttagaa gaaagaattt
    30061 tccaagtctg tttggctgcg ggctttgaag ccgattttca atcttggcgt caggccttaa
    30121 aagcggagtc tgtctatcat ttttttcatg atatcattcc agtctttgaa aaactcgggc
    30181 atgttgacct atcagataaa ctagaagagc tttatagcct agcgagtcct caggtgcaga
    30241 ttgcctccaa gggaggtctc ttggaaatcc agtttgattt tcaagatatt gcccaggagg
    30301 aaatcgacca agccatacag gccttggttg ccaatcagga tttttatatt gattcgtcta
    30361 atcaagttta ctttttcgat gaagaaacca agaaaattcg ccaaaatcta caggaactgg
    30421 ggcaatttga attaaaagat gggaccttgc aggctcggaa atccttggcc tacagtttag
    30481 ctcatctctt tga
//
LOCUS       DAVHTH010000023        29963 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.023, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000023 DAVHTH010000000
VERSION     DAVHTH010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 29963)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29963)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29963
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.023"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            <1..1627
                     /gene="nanB"
                     /locus_tag="VVR63_001064"
     CDS             <1..1627
                     /gene="nanB"
                     /locus_tag="VVR63_001064"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="neuraminidase NanB"
                     /protein_id="HEU6129091.1"
                     /translation="YTMYVNGIEVFSETVDTFLPISNINGIDKATLGAVNREGKEHYL
                     AKGSIGEISLFNKAISDQEVSTIPLSNPFQLIFQSGDSTQANYFRIPTLYTLSSGRVL
                     SSIDARYGGTHDSKSKINIATSYSDDNGKTWSEPIFAMKFNDYEEQLVYWPRDNKLKN
                     SQISGSASFIDSSIVEDKKSGKTILLADVMPAGIGNNNANKADSGFKEINGHYYLKLK
                     KNGDNDFRYTVRENGVVYDETTNKPTNYTINDKYEVLEGGKSLTVEQYSVDFDSGSLR
                     EKHNGKQVPMNVFYKDSLFKVTPTNYIAMTTSQNRGESWEQFKLLPPFLGEKHNGTYL
                     CPGQGLALKSSNRLIFATYTSGELTYLISDDSGQTWKKSSASIPFKNATAEAQMVELR
                     DGVIRTFFRTTTGKIAYMTSRDSGETWSEVSYIDGIQQTSYGTQVSAIKYSQLIDGKE
                     AVILSTPNSRSGRKGGQLVVGLVNKEDDSIDWKYHYDIDLPSYGYAYSAITELPNHHI
                     GVLFEKYDSWSRNELHLSNVVQYIDLEINDLTK"
     gene            1639..2742
                     /locus_tag="VVR63_001065"
     CDS             1639..2742
                     /locus_tag="VVR63_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEU6129092.1"
                     /translation="MVKYGVVGAGYFGAELARYMQKNDGAEITLLYDPDNAEAIAEEL
                     GAKVASSLDELVSSDEVDCVIVATPNNLHKEPVIKAAQHGKNVFCEKPIALSYQDCRE
                     MVDACKENNVTFMAGHIMNFFNGVHHAKELINQGVIGDVLYCHTARNGWEEQQPSVSW
                     KKIREKSGGHLYHHIHELDCVQFLMGGMPETVTMTGGNVAHEGEHFGDEDDMIFVNME
                     FSNKRFALLEWGSAYRWGEHYVLIQGSKGAIRLDLFNCKGTLKLDGQESYFLIHESQE
                     EDDDRTRIYHSTEMDGAIAYGKPGKRTPLWLSSVIDKEMRYLHEIMEGAPVSEEFAKL
                     LTGEAALEAIATADACTQSMFEDRKVKLSEIVK"
     gene            2916..3614
                     /locus_tag="VVR63_001066"
     CDS             2916..3614
                     /locus_tag="VVR63_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEU6129093.1"
                     /translation="MPQISKEALIEQIKDGIIVSCQALPHEPLYTEAGGVIPLLVKAA
                     EQGGAVGIRANSVRDIKEIKEVTKLPIIGIIKRDYPPQEPFITATMKEVDELAELDIE
                     VIALDCTKRERYDGLEIQEFIRQVKEKYPNQLLMADTSIFEEGLAAVEAGIDFVGTTL
                     SGYTSYSPKVDGPDFELIKKLCDAGVDVIAEGKIHTPEQAKQILEYGVRGIVVGGAIT
                     RPKEITERFVASLK"
     gene            3633..5150
                     /locus_tag="VVR63_001067"
     CDS             3633..5150
                     /locus_tag="VVR63_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEU6129094.1"
                     /translation="MFKVLQKVGKAFMLPIAILPAAGLLLGIGGALSNPTTIATYPIL
                     DNSIFQSIFQVMSSAGEVVFSNLSLLLCVGLCIGLAKRDKGTAALAGVTGYLVMTATI
                     KALVKLFMAEGSAIDTGVIGALAVGIVAVYLHNRYNNIQLPSALGFFGGSRFVPIVTS
                     FSSILIGFVFFVIWPPFQQLLVSTGGYISQAGPIGTFLYGFLMRLSGAVGLHHIIYPM
                     FWYTELGGVETIAGQTVVGAQKIFFAQLADPAHSGLFTEGTRFFAGRFSTMMFGLPAA
                     CLAMYHSVPKNRRKKYAGLFFGVALTSFITGITEPIEFMFLFVSPVLYVVHAFLDGVS
                     FFIADVLNISIGNTFSGGVIDFTLFGILQGNAKTNWVLQIPIGLIWSVLYYIIFRWFI
                     TQFNVLTPGRGEEVDSKEISESADSTSNTADYLKQDSLQIIRALGGSNNIEDVDACVT
                     RLRVAVKEVNQVDKALLKQIGAVDVLEVKGGIQAIYGAKAILYKNSINEILGVDD"
     gene            5275..6603
                     /locus_tag="VVR63_001068"
     CDS             5275..6603
                     /locus_tag="VVR63_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU6129095.1"
                     /translation="MKFRKLACTVLASAAVLGLAACGNSGGSKDAGKSGGDGAKTEIT
                     WWAFPVFTQEKTGDGVGTYEKSIIEAFEKANPDVKVKLETIDFKSGPEKITTAIEAGT
                     APDVLFDAPGRIIQYGKNGKLAELNDLFTDDFVKDVNNENIVQASKAGDKAYMYPISS
                     APFYMAMNKKMLEDAGVANLVKEGWTTDDFEKVLKALKDKGYTPGSLFSSGQGGDQGT
                     RAFISNLYSGSVTDEKVSKYTTDDPKFVKGLEKATGWIKDNLLNNGSQFDGGADIQNF
                     ANGQTSYTILWAPAQNGIQAKLLEASKVEVVEVPFPSDEGKPALEYLVNGFAVFNNKD
                     DKKVAASKKFIQFIADDKEWGPKDVVRTGAFPVRTSFGKLYDDKRMETISSWTQYYSP
                     YYNTIDGFAEMRTLWFPMLQSVSNGDEKPADALKAFTEKANETIKKAMKQ"
     gene            6856..7722
                     /locus_tag="VVR63_001069"
     CDS             6856..7722
                     /locus_tag="VVR63_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU6129096.1"
                     /translation="MRETVISYAFLAPVLFFFVIFVLAPMIMGFITSFFNYSMTSFEF
                     VGLDNYIRMFKDPVFTKSLINTVILVIGSVPVVVLFSLFVASQTYHQNAIARSFYRFV
                     FFLPVVTGSVAVTVVWKWIYDPLSGILNFVLKSSHIISQNISWLGDKNWALMAIMIIL
                     LTTSVGQPIILYIAAMGNIDNSLVEAARVDGATEFQVFWKIKWPSLLPTTLYIAIITT
                     INSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFQLTEYGYANTIGVFLAIMIAIVSF
                     VQFKVLGNDVEY"
     gene            7738..8577
                     /locus_tag="VVR63_001070"
     CDS             7738..8577
                     /locus_tag="VVR63_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU6129097.1"
                     /translation="MQSTEKKPLTAFTVISTIILLLLTVLFIFPFYWILTGAFKSQPD
                     TIVIPPQWFPKMPTMENFQQLMVQNPALQWMWNSVFISLVTMFLVCATSSLAGYVLAK
                     KRFYGQRILFAIFIAAMALPKQVVLVPLVRIVNFMGIHDTLWAVILPLIGWPFGVFLM
                     KQFSENIPTELLESAKIDGCGEIRTFWSVAFPIVKPGFAALAIFTFINTWNDYFMQLV
                     MLTSRNNLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGA
                     VKG"
     gene            8849..9301
                     /locus_tag="VVR63_001071"
     CDS             8849..9301
                     /locus_tag="VVR63_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEU6129098.1"
                     /translation="MIFDDLKNITFYKGIHPNLDKAIDYLYQHRKDSFELGKYEIDGD
                     KVFLVVQENVLNQVENNRFEHHKNYADLHLLIEGHEYSSYGSRIKDEAVAFDEASDIG
                     FVHCHEHYPLLLGYHNFAIFFPGEPHQPNGYAGMEEKVRKYLFKILID"
     gene            9398..9742
                     /locus_tag="VVR63_001072"
     CDS             9398..9742
                     /locus_tag="VVR63_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6129099.1"
                     /translation="MVSSKYAARASFLDGQGITVDEMAWIIRGIVTALIGRYIKLGTY
                     AVKYGISMARSILSRAAATAAARVGLLTKIFGWILRIAVLAADVYGNFANNIAVAWDA
                     HDKIPNNGRINF"
     gene            10029..10673
                     /locus_tag="VVR63_001073"
     CDS             10029..10673
                     /locus_tag="VVR63_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEU6129100.1"
                     /translation="MAQKGVSLIKAAFDTDNFLMRFSEKVLDIVTANLLFVVSCLPIV
                     TIGVAKISLYETMFEVKKSRRVPVFKIYLRSFKQNLKLGLQLGLMELGIVFLTLSDLY
                     LFWGQTALPFQLLKAICLGILIFLTIVMLASYPIAARYDLTWKEVLQKGLILASFNFP
                     WFFLMLAILVLIVMVLYLSAFSLLLGGSVFLLFGFGLLVFIQTGLMEKIFAKYQ"
     gene            10842..11759
                     /locus_tag="VVR63_001074"
     CDS             10842..11759
                     /locus_tag="VVR63_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HEU6129101.1"
                     /translation="MSDLKKYEGVIPAFYACYDEQGEVSPERTRALVQYFIDKGVQGL
                     YVNGSSGECIYQSVEDRKLILEEVMAVAKGKLTIIAHVACNNTKDSMELARHAESLGV
                     DAIATIPPIYFRLPEYSVAKYWNDISSAAPNTDYVIYNIPQLAGVALTSSLYTEMLKN
                     PRVIGVKNSSMPVQDIQTFVSLGGEDHIVFNGPDEQFLGGRLMGAKAGIGGTYGAMPE
                     LFLKLNQLIADKDLETARELQYAINAIIGKLTAAHGNMYGVIKEVLKINEGLNIGSVR
                     SPLTPVTEDDRPVVEAAAALIRETKERFL"
     gene            11777..12661
                     /locus_tag="VVR63_001075"
     CDS             11777..12661
                     /locus_tag="VVR63_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEU6129102.1"
                     /translation="MTYYVAIDIGGTNIKYGLVDQEGQLLESHEMPTEAHKGGPHILQ
                     KTKDIVASYLEKGPVAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKKEIEESFAI
                     PCEIENDVNCAGLAEAVSGSGKGASVTLCLTIGTGIGGCLIMDGKVFHGFSNSACEVG
                     YMHMQDGAFQDLASTTALVEYVAAAHGDPVDQWNGRRIFKEATEGNKFCMEGIDRMVD
                     YLGKGLANICYVANPEVVILGGGIMGQEAILKPKIRTALKEALVPSLAEKTRLEFAKH
                     QNTAGMLGAYYHFKTKQS"
     gene            complement(12677..13528)
                     /locus_tag="VVR63_001076"
     CDS             complement(12677..13528)
                     /locus_tag="VVR63_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEU6129103.1"
                     /translation="MDKPDIATVIDSHFEEMTDLEQEIARYFLQAETIQDDLSSQQVT
                     QKLHISQAALTRFAKKCGFTGYREFIFQYQHEAENQANQVSKHSPLTKRVLRSYSNMR
                     EQTQDLIDEVQLERIAQLIEDAERVYFFGTGSSGLVAREMKLRFMRLGVVCEALTDQD
                     GFAWTTSIMDENCLVLGFSLSGSTPSILDSLLDAKEMGAKTVLFSSVPNKDSQAYTET
                     VLVATHSQPSYIQRISAQLPMLFFIDLIYAYFLEINRESKEKIFNSYWENKKLNGYRR
                     QKRVRKS"
     gene            13722..15779
                     /gene="pbp2b"
                     /locus_tag="VVR63_001077"
     CDS             13722..15779
                     /gene="pbp2b"
                     /locus_tag="VVR63_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2B"
                     /protein_id="HEU6129104.1"
                     /translation="MRLICMRKFNSHSIPIRLNLLFSIVILLFMTIIGRLLYMQVLNK
                     DFYEKKLASASQTKVTTSSARGEIYDASGKPLVENTLKQVVSFTRSNKMTATDLKEIA
                     KKLLTYVSISSPNLTERQLADYYLADPEIYKKTVEALPSEKRLDSDGNRLSESELYNN
                     AVDSVPTSQLNYTEDEKKEIYLFSQLNAVGNFATGTIVTDPLNDSQVAVIASISKEMP
                     GISISTSWDRKVLETSLSSIVGSVSSEKAGLPAEEAESYLKKGYSLNDRVGTSYLEKQ
                     YEETLQGKRSVKEIHLDKYGNMESVDTIEEGSKGNNIKLTIDLAFQDSVDALLKSYFN
                     SELGNGGAKYSEGVYAVALNPKTGAVLSMSGIKHDLKTGELTPDSLGTVTNVFVPGSV
                     VKAATISSGWENGVLSGNQTLTDQPIVFQGSAPIYSWYKLAYGSFPITAVEALEYSSN
                     AYMVQTALGIMGQTYQPNMFVGTSNLETAMGKLRATFGEYGLGAATGIDLPDESTGFV
                     PKEYSFANYITNSFGQFDNYTPMQLAQYVATIANNGVRVAPRIVEGIYGNNDKGGLGD
                     LIQQLQPTEMNKVNISDSDMSILHQGFYQVAHGTSGLTTGRAFSNGALVSISGKTGTA
                     ESYVADGQQATNTNAVAYAPSDNPQIAVAVVFPHNTNLTNGVGPSIARDIINLYQKYH
                     PMN"
     gene            15790..16386
                     /gene="recR"
                     /locus_tag="VVR63_001078"
     CDS             15790..16386
                     /gene="recR"
                     /locus_tag="VVR63_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HEU6129105.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSADDVNEFA
                     KNLLSAKRELTYCSICGRLTDDDPCSICTDSTRDQTTILVLEDSRDVAAMENIQEYHG
                     LYHVLHGLISPMNGISPDDINLKSLMTRLMDSEVSEVIVATNATADGEATSMYLSRLL
                     KPAGIKVTRLARGLAVGADIEYADEVTLLRAIENRTEL"
     gene            16562..17605
                     /locus_tag="VVR63_001079"
     CDS             16562..17605
                     /locus_tag="VVR63_001079"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HEU6129106.1"
                     /translation="MKQTIILLYGGRSAEREVSVLSAESVMRAVNYDRFTVKTFFISQ
                     SGDSIKTQEFSHAPGQEDRLMTNETIDWDKKVAPSAIYEEGAVVFPVLHGPMGEDGSV
                     QGFLEVLKMPYVGCNILSSSLAMDKITTKRVLESAGIAQVPYVAIVEGDDVTAKIAEV
                     EEKLAYPVFTKPSNMGSSVGISKSENQEELRQALKLAFRYDSRVLVEQGVNAREIEVG
                     LLGNYDVKSTLPGEVVKDVAFYDYDAKYIDNKVTMDIPAKISDDVVAVMRQNAETAFR
                     AIGGLGLSRCDFFYTDKGEIFLNELNTMPGFTQWSMYPLLWENMGISYPELIERLVDL
                     AKESFDKREAHLI"
     gene            17689..19062
                     /locus_tag="VVR63_001080"
     CDS             17689..19062
                     /locus_tag="VVR63_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HEU6129107.1"
                     /translation="MKLTIHEIAQVVGAKNDISIFEDTQLEKAEFDSRLIGTGDLFVP
                     LKGARDGHDFIETAFENGAAVTLSEKEVSNHPYILVDDVLTAFQSLASYYLEKTTVDV
                     FAVTGSNGKTTTKDMLAHLLSTRYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMG
                     QDHLGDIHLLSELARPKTAIVTLVGEAHLAFFKDRSEIAKGKMQIADGMASGSLLLAP
                     ADPIVEDYLPIDKKVVRFGQGAELEITDLVERKDSLTFKANFLEQALDLPVTGKYNAT
                     NAMIASYVALQEGVSEEQIRLAFQHLELTRNRTEWKKAANGADILSDVYNANPTAMKL
                     ILETFSAIPANEGGKKIAVLADMKELGDQSVQLHNQMILSLSPDVLDIVIFYGEDIAQ
                     LAQLASQMFPIGHVYYFKKTEDQDQFEDLVKQVKESLGAYDQILLKGSNSMNLAKLVE
                     SLENECK"
     gene            19049..19660
                     /locus_tag="VVR63_001081"
     CDS             19049..19660
                     /locus_tag="VVR63_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU6129108.1"
                     /translation="MNASDFAKYLQRMIALTDTGLTFTKDPFDRERYEDLRSLLSEML
                     NQVSDLDADEVAELLKPTSAYATPLMDVRAWIVEDEKICLVRGQGENDWALPGGFGEV
                     GYSPTENILKEIEEETGFKAKVERLLAVFDTNRFQLQSKQYAKFVFECKLLDGQFQEN
                     QEIADLQFFAIDQLPNLSEKRITKEQIELLWQVYQGHRGQYLD"
     gene            19751..20455
                     /locus_tag="VVR63_001082"
     CDS             19751..20455
                     /locus_tag="VVR63_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HEU6129109.1"
                     /translation="MNLWDIFFTTQATEPPKFDLFWYVSLFTLLALTFYTAHRYRENK
                     VYQRFFQILQTVQLILLYGWYWVNHMPLSESLPFYHCRMAMFVVLLLPGQSKYKQYFA
                     LLGTFGTLAAFVYPVPDAYPFPHITILSFIFGHLALLGNSLVYLLRQYNARLLDVKGI
                     FLMTFALNALIFVVNLVTGGDYGFLTKPPLVGDHGLVANYLLVSIVLVATISLTKKIL
                     EFFLAQEAEKMIAKEA"
     gene            20674..22047
                     /gene="ftsA"
                     /locus_tag="VVR63_001083"
     CDS             20674..22047
                     /gene="ftsA"
                     /locus_tag="VVR63_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HEU6129110.1"
                     /translation="MAREGFFTGLDIGTSSVKVLVAEQRNGELNVIGVSNAKSKGVKD
                     GIIVDIDAAATAIKSAISQAEEKAGISIKSVNVGLPGNLLQVEPTQGMIPVTSDTKEI
                     TDQDVENVVKSALTKSMTPDREVITFIPEEFIVDGFQGIRDPRGMMGVRLEMRGLLYT
                     GPRTILHNLRKTVERAGVQVENVIISPLAMVQSVLNEGEREFGATVIDMGAGQTTVAT
                     IRNQELQFTHILQEGGDYVTKDISKVLKTSRKLAEGLKLNYGEAYPPLASKETFQVEV
                     IGEVEAVEVTEAYLSEIISARIKHILEQIKQELDRRRLLDLPGGIVLIGGNAILPGMV
                     ELAQEVFGVRVKLYVPNQVGIRNPAFAHVISLSEFAGQLTEVNLLAQGAIKGENDLSH
                     QPISFGGMLQKTAQFVQSTPVQPAPAPEVEPVAPTEPMADFQQASQNKPKLADRFRGL
                     IGSMFDE"
     gene            22064..23323
                     /gene="ftsZ"
                     /locus_tag="VVR63_001084"
     CDS             22064..23323
                     /gene="ftsZ"
                     /locus_tag="VVR63_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000144288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HEU6129111.1"
                     /translation="MTFSFDTAAAQGAVIKVIGVGGGGGNAINRMVDEGVTGVEFIAA
                     NTDVQALSSTKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEETLTEAISGADMVFI
                     TAGMGGGSGTGAAPVIARIAKDLGALTVGVVTRPFGFEGSKRGQFAVEGINQLREHVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITNPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERVVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDLTLIEA
                     EEASQIVNQAAGQGVNIWLGTSIDESMRDEIRVTVVATGVRQDRVEKVVAPQARSATN
                     YRETVKPAHSHGFDRHFDMAETVELPKQNPRRLEPTQASAFGDWDLRRESIVRTTDSV
                     VSPVERFEAPISQDEDELDTPPFFKNR"
     gene            23328..23999
                     /locus_tag="VVR63_001085"
     CDS             23328..23999
                     /locus_tag="VVR63_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HEU6129112.1"
                     /translation="MNVKENTELVFREVAEASLSAHRESGSVSVIAVTKYVDVPTAEA
                     LLPLGVHHIGENRVDKFLEKYEALKDRDVTWHLIGTLQRRKVKDVIQYVDYFHALDSV
                     KLAGEIQKRSDRVIKCFLQVNISKEESKHGFSREELLEILPELARLDKIEYVGLMTMA
                     PFEASSEQLKEIFKAAQDLQREIQEKQIPNMPMTELSMGMSRDYKEAIQFGSTFVRIG
                     TSFFK"
     gene            24009..24548
                     /locus_tag="VVR63_001086"
     CDS             24009..24548
                     /locus_tag="VVR63_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HEU6129113.1"
                     /translation="MSLKDRFDRFIDYFTEDEDSSLPYEKRDEPVFTPVNSSQEPALP
                     MNQPSQSAGTKENNITRLHARQQELANQSQRATDKVIIDVRYPRKYEDATEIVDLLAG
                     NESILIDFQYMTEVQARRCLDYLDGACHVLAGNLKKVASTMYLLTPVNVIVNVEDIRL
                     PDEDQQGEFGFDMKRNRVR"
     gene            24548..24811
                     /locus_tag="VVR63_001087"
     CDS             24548..24811
                     /locus_tag="VVR63_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HEU6129114.1"
                     /translation="MIFLIRMIYNAVDIYSLILVAFAVMSWFPGAYESSLGRWIVALV
                     KPVLAPLQRLPLQIAGLDLSVWVAIVLVRFLGENLVRFLAMIG"
     gene            24808..25593
                     /locus_tag="VVR63_001088"
     CDS             24808..25593
                     /locus_tag="VVR63_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HEU6129115.1"
                     /translation="MNKGIYQHFSIEDRPFLDKGMEWIKKVEDSYAPFLTPFINPHQE
                     KLLKILAKTYGLACSSSGEFVSSEYVRVLLYPDYFQPEFSDFEISLQEIVYSNKFEHL
                     THAKILGTVINQLGIERKLFGDILVDEERAQIMINQQFLLLFQDGLKKIGRIPVSLEE
                     RPFTEKIDKLEQYRELDLSVSSFRLDVLLSNVLKLSRNQANQLIEKKLVQVNYHVVDK
                     SDYTVQVGDLISVRKFGRLRLLQDKGQTKKEKKKITVQLLLSK"
     gene            25602..26390
                     /gene="divIVA"
                     /locus_tag="VVR63_001089"
     CDS             25602..26390
                     /gene="divIVA"
                     /locus_tag="VVR63_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIVA"
                     /protein_id="HEU6129116.1"
                     /translation="MPITSLEIKDKTFGTRFRGFDPEEVDEFLDIVVRDYEDLVRANH
                     DKNLRIKSLEERLSYFDEIKDSLSQSVLIAQDTAERVKQAAHERSNNIIHQAEQDAQR
                     LLEEAKYKANEILRQATDNAKKVAVETEELKNKSRVFHQRLKSTIESQLAIVESSDWE
                     DILRPTATYLQTSDEAFKEVVSEVLGEPIPAPIEEEPIDMTRQFSQAEMEELQARIEV
                     ADKELSEFEAQIKQEVETPTPVVSPQVEEEPLLIQLAQCMKNQK"
     gene            26738..29530
                     /locus_tag="VVR63_001090"
     CDS             26738..29530
                     /locus_tag="VVR63_001090"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HEU6129117.1"
                     /translation="MKLKDTLNLGKTAFPMRAGLPTKEPVWQKEWEDAKLYQRRQELN
                     EGKPHFVLHDGPPYANGNIHVGHAMNHISKDIIIRSKSMSGFNAPYIPGWDTHGLPIE
                     QVLAKQGVKRKEMDLVEYLKLCREYALSQVYKQRDDFKRLGMSGDWENLYVTLTPDYE
                     AAQIRVFGEMANKGYIYRGAKPVYWSWSSESALAEAEIEYHDLVSTSLYYANKVKDGK
                     GILDTDTYIVVWTTTPFTITASRGLTVGADIDYVLVQPASETRKFVVAAELLTSLSEK
                     FGWADVQVLATYRGQELNHIVTEHPWDTAVDELVILGDHVTTDSGTGIVHTAPGFGED
                     DYNVGIANGLEVAVTVDERGIMMANAGPEFEGQFYDKVVPTVIEKLGNLLLAQEEISH
                     SYPFDWRTKKPIIWRAVPQWFASVSKFRQEILDAIDKVKFHTEWGKVRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMTAETIEHVAQLFEVHGSSIWWERDAKDLLPEGF
                     THPGSPNGEFKKETDIMDVWFDSGSSWNGVLVNRPNLTYPADLYLEGSDQYRGWFNSS
                     LITSVANHGVAPYKQILSQGFTLDGKGEKMSKSLGNTIAPSDVEKQFGAEILRLWVTS
                     VDSSNDVRISMDILSQVSETYRKIRNTLRFLIANTSDFNPAQDVVAYDELRSVDKYMT
                     IRFNQLVKTIRDAYADFEFLTIYKALVNFINVDLSAFYLDFAKDVVYIEGAKSLERRQ
                     MQTVFYDILVKITKLLTPILPHTAEEIWSYLEFEAEDFVQLSELPEAQTFANQEEVLD
                     TWAAFMDFRGQAQKALEEARNAKVIGKSLEAHLTVYPNEVVKTLLEAVNSNVAQLLIV
                     SDLTIAEGPAPEAALSFEDVAFTVERAAGQVCDRCRRIDPTTAERSYQAVICDHCASI
                     VEENFAEAVAEGFEEK"
BASE COUNT         9138 a         5343 c         6589 g         8893 t
ORIGIN      
        1 atacacaatg tatgttaatg gaatagaagt gttctctgaa acagttgata catttttgcc
       61 aatttcaaat ataaatggta tagataaggc aacactagga gctgttaatc gtgaaggtaa
      121 ggaacattac ctcgcaaaag gaagtattgg tgaaatcagt ctatttaaca aagcaattag
      181 tgatcaggaa gtttcaacta ttcccttgtc aaatccattt cagttaattt tccaatcagg
      241 agattctact caagctaact attttagaat accgacacta tatacattaa gtagtggaag
      301 agttctatca agtattgatg cacgttatgg tgggactcat gattctaaaa gtaagattaa
      361 tattgccact tcttatagtg atgataatgg gaaaacgtgg agtgagccaa tttttgctat
      421 gaagtttaat gactatgagg agcagttagt ttactggcca cgagataata aattaaagaa
      481 tagtcaaatt agtggaagtg cttcattcat agattcatcc attgttgaag ataaaaaatc
      541 tgggaaaacg atattactag ctgatgttat gcctgcgggt attggaaata ataatgcaaa
      601 taaagccgac tcaggtttta aagaaataaa tggtcattat tatttaaaac taaagaagaa
      661 tggagataac gatttccgtt atacagttag agaaaatggt gtcgtttatg atgaaacaac
      721 taataaacct acaaattata ctataaatga taagtatgaa gttttggagg gaggaaagtc
      781 tttaacagtc gaacaatatt cggttgattt tgatagtggc tctttaagag aaaaacataa
      841 tggaaaacag gtccctatga atgttttcta caaagattcg ttatttaaag tgactcctac
      901 taattatata gcaatgacaa ctagtcagaa tagaggagag agttgggaac aatttaagtt
      961 gttgcctccg ttcttaggag aaaaacataa tggaacttac ttatgtcccg gacaaggttt
     1021 agcattaaaa tcaagtaaca gattgatttt tgcaacatat actagtggag aactaaccta
     1081 tctcatttct gatgatagtg gtcaaacatg gaagaaatcc tcagcttcaa ttccgtttaa
     1141 aaatgcaaca gcagaagcac aaatggttga actgagagat ggtgtgatta gaacattctt
     1201 tagaaccact acaggtaaga tagcttatat gactagtaga gattctggag aaacatggtc
     1261 ggaagtttcg tatattgatg gaatccaaca aacttcatat ggcacacaag tatctgcaat
     1321 taaatactct caattaattg atggaaaaga agcagtcatt ttgagtacac caaattctag
     1381 aagtggccgt aagggaggtc aattagttgt cggtttagtc aataaagaag atgatagtat
     1441 tgattggaaa taccactatg atattgattt gccttcgtat ggttatgcct attctgcgat
     1501 tacagaattg ccaaatcatc acataggtgt actgtttgaa aaatatgatt cgtggtcgag
     1561 aaatgaattg catttaagca atgtagttca gtatatagat ttggaaatta atgatttaac
     1621 aaaataaagg agaaaaacat ggttaaatac ggtgttgttg gagcagggta ttttggagct
     1681 gaattggctc gctacatgca aaagaatgat ggagcagaga ttactcttct ctatgatcca
     1741 gataatgcag aggcgattgc agaagaattg ggagcaaaag tagcaagttc cttagatgag
     1801 ttggtttcta gcgatgaagt agattgtgtt atcgtcgcaa ctccaaataa tcttcataag
     1861 gaaccggtta ttaaggctgc acagcatggt aaaaatgttt tctgtgaaaa accaattgcg
     1921 ctttcttatc aagattgtcg cgagatggta gatgcgtgta aagaaaacaa tgtaaccttt
     1981 atggcaggac atattatgaa tttctttaat ggtgttcatc atgcaaaaga actcattaat
     2041 caaggagtta tcggagacgt tctatattgt catacagctc gtaatggttg ggaagaacaa
     2101 caaccgtcag tatcatggaa aaaaattcgt gaaaaatcag gtggtcactt gtatcaccac
     2161 atccatgaat tggattgcgt tcaattcctt atggggggca tgcctgaaac tgtaaccatg
     2221 acaggtggaa atgtggccca tgaaggtgaa catttcggtg atgaagatga tatgattttt
     2281 gtcaatatgg aattttctaa taagcgtttt gctttgttag aatggggttc agcttatcgt
     2341 tggggtgaac attatgtctt aatccaagga agcaaaggtg ccatccgctt agacttattc
     2401 aactgtaaag gaactcttaa gctagatggg caagaaagct atttcttgat tcacgaatcg
     2461 caagaagaag atgatgatcg gactcgtatc tatcatagta cagagatgga tggagcaatt
     2521 gcttatggta aaccaggtaa acgtactcca ttatggctat catctgtcat tgataaagaa
     2581 atgcgctatc tgcatgagat tatggaagga gctccagtat cagaagaatt tgcaaaactt
     2641 ttgacaggtg aagctgccct agaagcaatt gctactgcag atgcttgtac ccagtctatg
     2701 tttgaagatc gcaaagtaaa attgtcagaa attgtaaaat aaattttggt attctcctat
     2761 ttataggtcg acttgctcct ctgaaagtac ttttagagga gctgtttgac tttgctagtt
     2821 tttgaaactg aaatctatta tactacaaac tattgaaagc gttttaattt taaggtataa
     2881 taatctcata gaaataaaga aaaggaggaa agaggatgcc acagattagc aaagaagcct
     2941 tgattgagca aatcaaagat ggaatcatcg tttcttgtca ggctcttcct catgaaccgc
     3001 tttatacaga agcgggaggg gtgattccct tgctggtcaa agcggctgag caaggtggag
     3061 cagtcggtat ccgagcaaac agtgttcgcg atatcaagga aattaaggaa gtcactaaac
     3121 ttccaatcat tgggattatc aaacgtgatt atccacctca ggaacccttc atcacggcta
     3181 ctatgaaaga agttgatgaa ttggcagaac tggacatcga ggtgattgct ctggattgta
     3241 ccaagcgtga acgctacgat ggtttggaaa ttcaagagtt cattcgtcag gttaaggaga
     3301 aatatcctaa tcagcttttg atggctgata ctagtatctt cgaagaaggg ctagcagctg
     3361 tagaagcagg aattgacttt gtcggaacaa ccttatcagg ctacacatcc tacagtccaa
     3421 aagtagacgg tccagatttt gaattgatta agaaactctg tgatgccggt gtagatgtca
     3481 ttgcagaagg aaaaattcat acaccagaac aagccaaaca aatccttgaa tatggagtgc
     3541 gaggcatcgt tgttggtggc gccattacta gaccaaaaga gattacagaa cgcttcgttg
     3601 ctagtcttaa ataagatgtg agggggagtt ttatgtttaa agttttacaa aaagttggaa
     3661 aagcttttat gttacctata gctatacttc ctgcagcagg tctacttttg gggattggtg
     3721 gtgcactttc aaacccaacc acgatagcaa cttatccaat actagacaat agtatttttc
     3781 aatcaatatt ccaagtaatg agctctgcag gagaggttgt attcagtaat ttgtcactac
     3841 ttctctgtgt gggattatgt attggcttag cgaaacgaga taaaggaacc gctgcgttag
     3901 caggagtaac tggttactta gttatgactg caacgatcaa agctttggta aaacttttta
     3961 tggcagaagg atctgcaatt gatactggag ttattggagc attagctgtc ggaatagttg
     4021 ccgtatattt gcacaaccga tataacaata ttcaattacc ttccgcttta ggattctttg
     4081 gaggttcacg cttcgttcct attgttacat cgttctcttc tatcttgatt ggctttgtct
     4141 tctttgttat ttggccacct ttccaacaac ttcttgtttc tacaggtgga tatatttctc
     4201 aggcgggtcc aattggaact tttctatatg gatttttaat gagactttct ggagcagtag
     4261 gcttacatca tataatttac cctatgtttt ggtatactga acttggtggt gttgaaacta
     4321 ttgcaggaca aacagtggtt ggagctcaaa aaatattttt tgctcaatta gccgatccgg
     4381 cccattctgg attatttaca gaaggaacaa ggttttttgc aggtcgtttc tcaacaatga
     4441 tgttcggttt accggctgcc tgtttagcga tgtaccatag tgttcctaaa aatcgtcgta
     4501 aaaaatacgc gggtttgttt tttggagttg ctttaacatc ttttattacc ggtattacag
     4561 aaccaattga atttatgttt ctattcgtca gtccggttct atatgttgtt cacgcattcc
     4621 ttgatggtgt tagcttcttt attgcagacg tcttaaatat ttcaatagga aacacatttt
     4681 caggaggtgt aatcgatttc actttatttg gaattttgca ggggaacgct aagacgaatt
     4741 gggttcttca gattccaatt ggacttattt ggagtgtttt gtattatatt atttttagat
     4801 ggttcattac tcaattcaat gttctaacgc caggacgagg agaagaagta gattctaaag
     4861 aaatttctga atccgcagat tcaacttcaa atactgcaga ttatttaaaa caggatagcc
     4921 tacaaattat cagagccttg ggtggatcaa ataatataga agatgtagat gcttgtgtga
     4981 cacgtttacg tgtagctgta aaagaagtta atcaagttga taaagcactt ttaaaacaaa
     5041 ttggtgcagt tgatgtctta gaagtgaagg gtggcattca agcaatctat ggagcaaaag
     5101 caatcttata taaaaatagt attaatgaaa ttttaggtgt agatgattaa gtacttactg
     5161 acttaataaa aaacagagga gagtgatgga tgagtaggat gaaatgaaat cgcatataag
     5221 aaataaagaa ctcattatcc aagttggata cgcttattac ataggagaat acagatgaaa
     5281 tttagaaaat tagcttgtac agtacttgcg agtgctgcgg ttcttggtct tgctgcttgt
     5341 ggcaattctg gcggaagtaa agatgctggc aaatcaggtg gtgacggtgc caaaacagaa
     5401 atcacttggt gggcattccc agtatttacc caagaaaaaa ctggtgacgg tgttggaact
     5461 tatgaaaaat caatcatcga agcgtttgaa aaagccaatc cagatgtaaa agtgaaattg
     5521 gaaaccatcg acttcaagtc aggtcctgaa aaaatcacaa cagctatcga agctggaaca
     5581 gctccagacg tactctttga tgcaccagga cgtatcatcc aatacggtaa aaacggtaaa
     5641 ttggctgagt tgaacgacct cttcacagat gactttgtta aagatgtcaa caatgaaaac
     5701 atcgtacaag caagtaaagc tggagacaag gcttacatgt atccaattag ttctgcccca
     5761 ttctacatgg caatgaacaa gaaaatgtta gaagatgctg gagttgcaaa ccttgtaaaa
     5821 gaaggttgga caactgatga ttttgaaaaa gtattgaaag cacttaaaga caagggttac
     5881 acaccaggtt cattgttcag ttctggtcaa gggggagacc aaggaacacg tgcctttatc
     5941 tctaaccttt atagcggttc tgtaacagat gaaaaagtta gcaaatatac aactgatgat
     6001 cctaaattcg tcaaaggtct tgaaaaagca actggctgga ttaaagacaa tttgctcaat
     6061 aatggttcac aatttgacgg tggggcagat atccaaaact ttgccaacgg tcaaacatct
     6121 tacacaatcc tttgggcacc agctcaaaat ggtatccaag ctaaactttt agaagcaagt
     6181 aaggtagaag tggtagaagt accattccca tcagacgaag gtaaaccagc tcttgaatac
     6241 cttgtaaacg gatttgcagt attcaacaac aaagacgaca agaaagttgc agcatctaag
     6301 aaattcatcc aatttatcgc agatgacaaa gagtggggtc caaaagacgt agttcgtaca
     6361 ggtgccttcc cagttcgtac atcatttggc aaactttatg atgacaaacg tatggaaaca
     6421 atcagcagct ggactcaata ctactcacca tactacaaca ctattgatgg atttgctgaa
     6481 atgagaacac tttggttccc aatgttgcaa tctgtatcaa atggtgacga aaaaccagcg
     6541 gacgctttga aagccttcac tgaaaaagcg aacgaaacaa tcaaaaaagc tatgaaacaa
     6601 tagtccttag ttattctata aaaagtagtt ttttaaagaa cctaagagtg tataccccct
     6661 tttccctcta cacagatagt gtaagaaaag gggggctttt gtttaaaacg taagaaattg
     6721 tcacgaaatt aaaatgaagt tcttacataa gtgaatcata aaaaatttca ttttgatttt
     6781 aaaacagttc aagaaagtca aaaaattatt ctatttgaaa gagaggtgcc gactgtgaaa
     6841 gtcaataaaa tccgtatgcg ggaaacagtg atttcctatg ctttcctagc accagtgttg
     6901 ttcttctttg tcatctttgt attggctcca atgattatgg gctttattac aagtttcttt
     6961 aactactcta tgactagctt tgaatttgtg ggcttagata actatatccg tatgtttaaa
     7021 gatcctgtct ttacaaaatc tttgattaac acagttattt tggttattgg atctgtgcca
     7081 gttgttgttc tattctcact ctttgtagcg tcacagacct accatcaaaa tgctatcgct
     7141 agatcattct atcgtttcgt attcttcctt ccagttgtta caggtagtgt tgccgtaaca
     7201 gttgtatgga aatggattta tgacccacta tcagggattc taaactttgt ccttaagtcc
     7261 agccacatca tcagccaaaa catttcttgg ttgggagata aaaactgggc attgatggcg
     7321 attatgatta ttctcttgac cacttcagtt ggtcagccca tcatccttta tatcgctgcc
     7381 atggggaata ttgacaattc actggttgaa gcggcgcgtg ttgatggtgc aactgagttt
     7441 caagtttttt ggaagattaa atggccaagc cttcttccaa caactcttta tattgcaatc
     7501 atcacaacaa ttaactcatt ccagtgtttt gccttgattc agcttttgac atctggtggt
     7561 ccaaactact caacaagtac cttgatgtac tacctttacg aaaaagcctt ccaattgaca
     7621 gaatacggct atgccaacac aattggtgtc ttcttggcaa tcatgattgc tatcgtaagc
     7681 tttgttcaat ttaaagtact tggaaacgac gtagaatact aaagaaagga gacagctatg
     7741 caatctacag aaaaaaaacc attaacagcc tttactgtta tttcaacaat cattttgctc
     7801 ttgttgactg tgctgttcat ctttccattc tactggattt tgacaggggc attcaaatca
     7861 caacctgata caattgttat tcctcctcag tggttcccta aaatgccaac catggaaaac
     7921 ttccaacaac tcatggtgca gaaccctgcc ttgcaatgga tgtggaactc agtatttatc
     7981 tcattggtaa ccatgttctt agtctgtgca acctcatctc tagcaggtta tgtattggct
     8041 aaaaaacgtt tctatggtca acgcattcta tttgctatct ttatcgctgc tatggcgctt
     8101 ccaaaacaag ttgtccttgt accattggta cgtatcgtca acttcatggg aatccacgat
     8161 actctctggg cagttatctt gcctttgatt ggatggccat tcggtgtctt cctcatgaaa
     8221 cagttcagtg aaaatatccc tacagagttg cttgaatcag ctaaaatcga cggttgtggt
     8281 gagattcgta ccttctggag tgtagccttc ccgattgtga aaccagggtt tgcagccctt
     8341 gcaatcttta ccttcatcaa tacttggaat gactacttca tgcaattggt aatgttgact
     8401 tcacgtaaca atttgaccat ctcacttggg gttgcgacca tgcaggctga aatggcaacc
     8461 aactatggtt tgattatggc aggagctgcc cttgctgctg ttccaatcgt cacagtcttc
     8521 ctagtcttcc aaaaatcctt cacacagggt attactatgg gagcggtcaa aggataatac
     8581 tctgagaaaa tctcttcaaa ctacgtcagc gtcaccttgc catacttaag tattgcctgc
     8641 ggttagcttc ctagtttgtt cttcaatttt cattgagtat aggaaaatca atctatcaag
     8701 atacagaagt atattttata gatttagaga atatagaggt tataagtgtc tacaaaatgg
     8761 agggtatgca gttactttat gaagttttgt cagacactta taaacttaag aatggtttta
     8821 gttaactatc agaaacgaag gaaagagtat gatttttgac gatttgaaaa acatcacctt
     8881 ttacaaaggg attcatccca atttagacaa ggctatcgac tatctctacc aacatcgtaa
     8941 agattcattc gaattaggaa agtatgagat tgatggagat aaagtctttc tagttgttca
     9001 ggaaaatgtc ctcaatcaag ttgagaataa tcgatttgaa caccataaga actatgcaga
     9061 tttgcatttg ctgatagaag ggcatgaata ttcgagctac ggttcacgta tcaaagacga
     9121 ggcagtagca ttcgacgaag cgagtgacat tggctttgtt cattgtcatg aacactaccc
     9181 actcttgttg ggttatcaca attttgcgat tttcttccca ggtgagccac atcagccaaa
     9241 tggttatgca ggcatggaag aaaaggttcg aaaatatctc tttaaaattt tgattgatta
     9301 aaaataggat gaattgtttt tttgtaaagc tttgataata ctctaccatg aaattgatct
     9361 ttgtgaggta gagaaatgag aataaaatat ttaaaaattg gtatcttcta agtatgctgc
     9421 aagagctagt ttcttagatg gacaggggat tacagttgat gagatggctt ggataattag
     9481 gggcattgtg actgcattga ttggtagata cataaaatta ggtacttatg cagttaagta
     9541 tggtattagt atggcgcgct cgatcttaag tagggcagct gcaactgcgg cagcaagagt
     9601 aggattattg actaagattt ttggatggat tttacgaata gctgtgctcg cagctgatgt
     9661 atatggtaat tttgccaaca atattgctgt agcttgggat gcacatgata aaatccctaa
     9721 caatggtcgt ataaactttt aaaatgcgag aatgaaagca ctttgtattt ttttattgta
     9781 tatgttagct tggacagtgc ttgcaatgat aatccgtgga gggctagatg gatttgatga
     9841 acacacttgg cgtactattt taattgcttc gctgtccggg atatatatag attatatgtc
     9901 catagataaa agtagaaaaa agtccaaaag aaaaaagaaa aaatagattt gttcatggta
     9961 gggacttatg aaagctttac tgacaaaaaa gaaaacagtt tacaaagaaa aatgatggag
    10021 gagcaaacat ggcacaaaaa ggagtaagcc ttatcaaggc agcatttgat acagataact
    10081 ttctcatgcg ttttagtgag aaagtcttgg acatcgtgac agccaatctt ctttttgtcg
    10141 tctcttgttt gcccatcgtg acgattggag tggctaaaat cagcctctac gagaccatgt
    10201 tcgaagttaa gaagagcaga cgggtgcctg tttttaaaat ctatctaaga tctttcaagc
    10261 aaaatctgaa actaggtctt cagctgggtt taatggagtt aggaattgtg tttcttaccc
    10321 tttcagatct ctatcttttc tggggtcaaa cagctctgcc cttccaattg ctgaaagcca
    10381 tttgtctagg cattctgatt ttccttacga ttgtgatgtt ggctagctat ccaatcgcgg
    10441 cacgttatga tttaacttgg aaagaagtgt tacaaaaagg gcttatcttg gctagtttta
    10501 actttccttg gttcttcctc atgttagcca ttcttgtcct cattgtgatg gttctttatc
    10561 tgtccgcctt cagtctactc ttaggtggct cagtcttcct actttttggg tttggactat
    10621 tggtctttat ccagactgga ttgatggaga aaattttcgc aaaataccaa taggagcctt
    10681 atttctgaaa ctactttcaa aggctccaaa cgctattcta taagcgagaa actaaaatct
    10741 aagtgtctat aagatattga aagccttttc ggtaaagtgt atactaaaga agtaaagaaa
    10801 aatctgcttt agcagaaaat aaaaataata ggagaaaatc tatgtcagat ttgaaaaaat
    10861 acgaaggtgt cattccagcc ttctacgcat gttatgatga gcaaggagaa gtaagtccag
    10921 agcgtacgcg tgccttggtt caatacttca ttgataaagg tgttcaaggt ctttatgtca
    10981 atggttcttc tggtgaatgt atctaccaaa gcgttgaaga tcgcaagttg attttggaag
    11041 aagtcatggc ggtagccaaa ggtaaattga ccattattgc ccatgttgct tgcaataata
    11101 ctaaagatag tatggaactt gctcgccatg ctgaaagctt gggagtagat gctattgcaa
    11161 cgattccacc aatttacttc cgcttgccag aatactcagt tgccaaatac tggaacgata
    11221 ttagttctgc agctccaaac acagactacg tgatttacaa cattcctcaa ttggcagggg
    11281 ttgctttgac ttcaagcctt tacacagaaa tgttgaaaaa tcctcgtgtt atcggtgtta
    11341 agaactcttc aatgccagtt caagatatcc aaacctttgt cagccttggc ggggaagacc
    11401 atattgtctt taacggtcca gatgaacagt tcctaggtgg ccgcctcatg ggtgctaagg
    11461 ctggtatcgg tggtacttat ggtgctatgc cagaactctt cttgaaactc aatcagttga
    11521 ttgcggataa agatttagaa acagcgcgtg aattgcagta tgctatcaac gcaatcattg
    11581 gtaaactcac tgctgcacat ggaaatatgt acggtgtcat caaagaagtt ttgaagatca
    11641 atgaaggctt gaatattggt tctgttcgtt caccattgac accagtgact gaagacgatc
    11701 gtccagttgt agaagcggct gcagccttga ttcgtgaaac caaggagcgc ttcctctaat
    11761 ctaaaaggag gtatttatga catactacgt tgcaattgat atcggtggaa ctaacatcaa
    11821 gtatggtttg gttgatcaag aggggcaact tcttgaatca catgaaatgc caacagaggc
    11881 gcataagggt ggacctcata tcttacaaaa gaccaaagat atcgtagcta gttatttaga
    11941 aaaaggccca gtagcaggtg ttgccatatc ttctgctggg atggtggatc cggataaggg
    12001 tgagattttc tatgctgggc cgcaaatccc taactacgca ggcacccagt tcaaaaagga
    12061 aatcgaagaa agctttgcta ttccttgtga gattgaaaat gatgtcaact gtgcaggtct
    12121 ggctgaggca gtatctggtt caggtaaggg agcaagtgtc accctttgct tgaccattgg
    12181 aacaggtatt ggtggttgtt tgattatgga tgggaaagtc ttccatggat ttagcaattc
    12241 agcctgtgaa gttggttata tgcatatgca ggatggagcg tttcaagatt tggcttctac
    12301 aacagccttg gtggagtatg tagcagcagc tcatggagat ccagttgacc agtggaatgg
    12361 tcgtcgtatc tttaaggaag ctacggaagg caataaattc tgcatggaag gtattgaccg
    12421 catggtagac tatctaggaa aaggtctggc aaatatttgc tacgttgcca atccagaagt
    12481 ggtcattctc ggtggcggta tcatgggaca agaggcgatt ctcaaaccga aaatccgcac
    12541 agccttgaaa gaggctttgg taccaagttt ggctgagaaa acaagattag aattcgccaa
    12601 gcaccaaaat accgcaggca tgttgggtgc ttattatcat tttaaaacaa aacaatccta
    12661 gtttggctta gccaaactag gattttctga cacgtttttg tctacgatag ccgttgagtt
    12721 tcttattttc ccaatagcta ttaaagattt tctccttgct ttcacgattg atttccaaaa
    12781 agtaggcata aatcaaatcg ataaagaaga gcataggaag ttgagcggat atacgttgga
    12841 tgtaggaagg ctggctgtgg gtagctacaa gaacggtctc agtataggcc tggctatctt
    12901 tattgggaac acttgaaaag agtacagtct ttgctcccat ctccttggca tccaatagac
    12961 tatctaaaat agaaggagtt gagcctgaaa gtgagaaacc aagtacgaga caattttcgt
    13021 ccataatgct ggttgtccag gcaaagccgt cttgatcggt caaagcttcg cagaccacac
    13081 ccagacgcat gaagcgtaat ttcatttcac gagcaacaag gccagaactt cctgttccga
    13141 agaagtagac acgctcagca tcttcgatta attgggcaat tcgttctagt tggacttcgt
    13201 caatcaagtc ttgtgtttgt tccctcatat tactatagct tctgaggact cgtttggtca
    13261 gtggactgtg cttggagact tggttggctt gattttctgc ctcatgttgg tattggaaaa
    13321 taaattctcg gtagccagta aagccacact ttttagcaaa gcgggtcagt gcagcttgag
    13381 agatatgtaa tttttgagtg acctgttggg aggaaaggtc atcttgaatg gtttctgctt
    13441 gtaaaaaata gcgagcgatt tcttgctcta ggtctgtcat ttcttcaaaa tgtgaatcaa
    13501 tgacagttgc gatatctggt ttgtccatag ggaaggctcc tttaaatgag tcgtgttgga
    13561 aaaagactag attattgaac ttttacattc attataacat ataatatagg gatggataaa
    13621 taaaaacgta tcttactgta aaaacgaaaa aaagcttctt tcttttccat aattttctgc
    13681 tcaaattgtg gtacaattaa gagtaagatt ttaagttaga aatgagactg atttgtatga
    13741 gaaaatttaa cagccattcg attccgattc ggcttaattt attgttttca atcgtcattt
    13801 tactctttat gaccattatt ggtcgtttgt tgtatatgca ggttttgaac aaggattttt
    13861 atgaaaaaaa gctagcctca gctagtcaga ccaaggtcac aaccagttct gctcgtgggg
    13921 aaatctatga tgctagtgga aaacctttgg tagaaaatac gttaaagcag gttgtttcct
    13981 ttacgcgtag caataaaatg acggctacag acttaaaaga aatagctaaa aagttactga
    14041 cttatgtgag catcagttcg ccaaatttga cagaacgcca gctggctgat tactatttgg
    14101 ctgatcctga aatctataaa aaaacagtgg aagctctccc aagtgagaaa cgcttggatt
    14161 cagatggcaa tcgcctatcc gaatcagaac tgtataacaa tgctgtcgat agtgtcccaa
    14221 caagtcaact aaactataca gaggatgaaa agaaagaaat ctatcttttt agtcagttaa
    14281 atgctgttgg aaactttgcg acaggaacca ttgtgacaga tcctctaaat gattctcagg
    14341 tggctgttat tgcctctatt tcaaaggaga tgcctggcat tagtatttct acttcttggg
    14401 atcgaaaggt tttggaaact tccctttctt ctatagtagg gagtgtatcc agtgaaaaag
    14461 ctggtctccc agcggaagaa gcagaatcct atcttaaaaa aggctattct ctaaatgacc
    14521 gtgttggaac ctcctatttg gaaaagcaat atgaagagac cttacaagga aaacgctcgg
    14581 taaaagaaat ccatctggat aaatatggca atatggaaag cgtggacaca attgaggaag
    14641 gtagtaaggg aaacaatatc aaactgacca ttgatttggc cttccaagat agcgtggatg
    14701 ctttgctgaa aagttatttc aattccgagc taggaaatgg tggagctaaa tattctgaag
    14761 gtgtctatgc agtcgccctt aacccaaaaa caggtgctgt tttatccatg tcagggatca
    14821 aacatgacct gaaaacggga gagttgactc ctgattcctt gggaacggta accaatgtct
    14881 ttgtcccagg ttcggttgtc aaggctgcga ccatcagctc aggttgggaa aatggtgttt
    14941 tatcaggaaa ccaaacctta acagatcagc ctattgtttt ccaaggttca gctccaattt
    15001 attcttggta taaattggca tatggatctt ttcctattac agctgtggaa gccttggagt
    15061 attcatccaa tgcttacatg gttcaaaccg ctcttggaat catgggccag acctatcaac
    15121 caaatatgtt tgttggaacc agcaatttgg aaacagctat gggaaaactt cgtgcgacct
    15181 ttggcgaata tggcttgggg gctgcgaccg gaattgacct accagatgaa tctactggat
    15241 ttgttcccaa agagtatagc tttgctaatt acatcaccaa ttcctttggg cagtttgata
    15301 actatacgcc catgcagttg gctcagtatg tagcaactat tgcaaataat ggtgttcgtg
    15361 tggctcctcg tattgttgaa ggcatttatg gtaataatga taagggagga ctgggtgact
    15421 tgattcagca actgcaaccg acagagatga ataaggtcaa tatatccgac tccgatatga
    15481 gcatcttgca ccaaggtttt tatcaggttg cccatggtac tagtggattg acaactggac
    15541 gtgccttttc aaatggtgcc ttggtatcca ttagcggaaa aacaggtaca gccgaaagct
    15601 atgtggcaga tggtcagcaa gcaaccaata ccaatgcggt ggcctatgcc ccatctgata
    15661 atccccaaat cgctgtcgca gtggtctttc ctcataatac caatctaaca aatggtgtag
    15721 gaccttccat tgcgcgtgac attatcaatc tgtatcaaaa ataccatcca atgaactaga
    15781 aaggaaatta tgctttatcc aacacctatt gccaagttga ttgacagtta ttctaagtta
    15841 ccaggtatcg ggattaagac ggctacgcgt ctggcctttt atacgattgg gatgtctgct
    15901 gatgatgtca atgaatttgc aaaaaatctc ctttctgcta agagagaatt gacatattgt
    15961 tctatttgtg gacgtttgac agacgacgat ccttgttcta tctgtactga ttcgactcgt
    16021 gaccagacaa caattttagt tcttgaggat agtagagatg tggcagccat ggaaaatatc
    16081 caagaatacc atggactcta tcatgtcctg catggcctca tttctcctat gaatggtatc
    16141 agtccggacg atatcaatct taagagcctt atgactcgtc ttatggatag tgaggtttca
    16201 gaagtgattg tggcgactaa tgctacagcg gatggtgaag cgacctccat gtatctttca
    16261 cgtttgctca agccggctgg tatcaaggtt acgcgtctag cacgaggtct cgctgtggga
    16321 gcggacattg agtatgcgga cgaagtgaca ctcttacgag cgattgaaaa tcggacagag
    16381 ttgtaagtgt aggcaaattt acgaactcca ttcatttata aaaaatcaaa gaggctgaaa
    16441 atcgttccta tcggcctctt tttgtatagt gtgatgagta gaatcaggtt caagttttaa
    16501 aaaaccaagc aaatatgata tactaaagag cgagtattct agtagaatta ggacaaataa
    16561 tatgaaacaa acgattattc ttttatatgg tggacggagt gcggaacgcg aagtctctgt
    16621 cctttcagct gagagtgtca tgcgtgcggt caattacgac cgtttcacag tcaagacttt
    16681 ctttatcagt cagtcaggtg actctatcaa aacgcaggaa tttagtcatg ctccggggca
    16741 agaagaccgt ctcatgacca atgaaaccat tgattgggat aagaaagttg caccaagtgc
    16801 tatctacgaa gaaggtgcag tggtctttcc agtccttcac gggccaatgg gagaagatgg
    16861 ctctgttcaa ggattcttgg aagttttgaa aatgccttac gttggttgca acattttgtc
    16921 atcaagtctt gccatggata aaatcacgac taagcgtgtt ctggaatctg ctggtattgc
    16981 ccaagttcct tatgtggcta tcgttgaagg cgatgatgtg actgctaaaa tagctgaagt
    17041 ggaagaaaaa ttggcttatc cagtcttcac taagccgtca aacatggggt ctagtgtcgg
    17101 tatttctaag tctgaaaacc aagaagaact ccgtcaagcc ttaaaacttg ccttccgata
    17161 tgacagccgt gtcttggttg agcaaggagt gaatgcccgt gaaattgagg ttggcctctt
    17221 gggtaactac gatgtcaaga gcacgctacc tggagaagtt gtcaaggacg ttgcctttta
    17281 tgactacgat gccaagtata ttgataacaa ggttactatg gatattcctg ccaaaatcag
    17341 tgatgatgtg gtggctgtca tgcgtcaaaa tgcagaaaca gccttccgtg ccattggtgg
    17401 ccttggtcta tctcgttgcg atttcttcta tacagataag ggagagattt ttctcaacga
    17461 gctcaatacc atgccaggtt tcacccagtg gtctatgtac ccactacttt gggaaaatat
    17521 ggggatcagc tacccagaac taatcgagcg tttggttgac cttgccaagg aaagttttga
    17581 caagcgcgaa gcgcatttga tataaaatga aagagagggt agaagccaga accatcactg
    17641 caaggtgact agagttctcg gacttcagcc ctttttaaag gagtagaaat gaaattaaca
    17701 atccatgaaa ttgcccaagt tgttggagcc aaaaatgata tcagtatctt tgaggacact
    17761 cagttagaaa aagctgagtt tgatagtcgt ttgattggaa ctggagattt atttgtgcca
    17821 cttaaaggtg cgcgtgatgg ccatgacttt attgaaacag cctttgaaaa tggtgcagca
    17881 gtaaccttgt ctgagaaaga ggtctcaaat catccttaca ttttagtaga tgatgttttg
    17941 acagcctttc aatccctagc atcctactat cttgaaaaaa cgactgttga tgtctttgct
    18001 gttacaggtt caaatggcaa gacaacgact aaggatatgt tggcgcattt actgtcaaca
    18061 agatacaaga cctacaaaac acaaggcaat tacaataatg agattggcct tccttacaca
    18121 gttcttcata tgcctgaagg aacagaaaag ttggttttgg agatgggaca ggatcacttg
    18181 ggagatattc atctcttgtc tgaattggct cgtccaaaaa cagccatcgt gaccttggtt
    18241 ggagaagctc atttggcctt tttcaaagat cgttctgaga ttgctaaagg aaaaatgcaa
    18301 attgcagacg gaatggcttc aggttccttg cttttagcgc cggctgaccc tatcgtagag
    18361 gactatttgc caattgataa aaaggtggtt cgttttggtc aaggagcaga gctggaaatt
    18421 actgacttgg ttgagcgtaa ggacagtctg acctttaagg ctaatttctt ggaacaagcc
    18481 cttgatttgc cagtaactgg caagtacaat gcgacaaatg ctatgattgc atcctatgtt
    18541 gccttgcaag aaggagtttc agaggagcaa attcgtttgg cattccaaca tcttgaattg
    18601 acgcgtaacc gtaccgagtg gaagaaagca gccaatggag cagatatcct gtcagatgtt
    18661 tacaatgcca atccaactgc tatgaaactg attttagaga ctttctctgc cattccagcc
    18721 aatgaaggtg gcaagaaaat tgcagtgttg gcggatatga aggagcttgg tgaccagtct
    18781 gttcaacttc ataatcagat gattttgagc ctctccccag atgtgcttga tatcgttatt
    18841 ttctatggag aagatattgc tcagttggct caattggcca gtcaaatgtt tccaatcggc
    18901 cacgtttact acttcaagaa aacagaagac caggatcaat ttgaagacct agtcaagcag
    18961 gttaaggaaa gccttggagc ctatgaccaa atcttgctaa aaggttctaa ctctatgaat
    19021 ctagccaaat tggtagaaag tttagaaaat gaatgcaagt gattttgcta agtatcttca
    19081 aagaatgatt gctcttacag atactggact aacctttaca aaggatccgt ttgaccgtga
    19141 gcgctacgaa gacttgcgaa gtctgttatc tgaaatgttg aatcaggtat cagaccttga
    19201 tgcagacgaa gtggcagaac tcttgaaacc gacctccgct tatgcgactc ctttaatgga
    19261 cgtccgtgct tggatagttg aggatgaaaa aatttgtctg gttaggggac aaggagagaa
    19321 tgattgggct ttgccaggtg gctttggcga ggtcggttat tcaccaactg aaaatattct
    19381 caaggaaatt gaagaagaaa ccggttttaa agccaaagtt gaacgactac tagctgtttt
    19441 tgataccaat cgtttccaac tacagagcaa acaatatgca aagtttgttt ttgaatgtaa
    19501 gcttctcgat ggacaatttc aagaaaatca agaaatcgct gaccttcaat tttttgcaat
    19561 tgaccaactg ccgaatttat ctgaaaaacg cattaccaag gagcaaatag agcttctttg
    19621 gcaggtttat caaggtcata gggggcaata tcttgactaa gaagatgatt atcgtatttc
    19681 taaatccatt tttaacaact agcatggtat aataatatgc aggaaaattt tgaattatga
    19741 ggaagactag atgaatttat gggatatttt ctttacgact caggcaaccg agccgcccaa
    19801 atttgacctt ttttggtatg ttagcctatt tacgctctta gccttaacct tttatacagc
    19861 ccatcgctat cgtgaaaata aggtttacca acgatttttc caaatcttgc agactgttca
    19921 gttaatcctt ctttatggtt ggtactgggt caatcatatg ccactgtcag aaagcctacc
    19981 cttttaccat tgccgtatgg ctatgtttgt ggtactcttg cttcctggtc aatccaaata
    20041 taaacaatac tttgcattat tgggaacatt tgggacatta gcagcctttg tttatccagt
    20101 gccagatgct tacccttttc cacatatcac cattctatcc tttatctttg gtcatttagc
    20161 actcttgggg aactctctag tttatctatt gagacagtat aatgcgcgat tgctggatgt
    20221 gaagggaatt tttctcatga cctttgccct aaatgccttg atttttgtgg tcaatttggt
    20281 gacaggtggc gattacggat ttttgacaaa accgccattg gttggggatc acggtctagt
    20341 agctaattat ttacttgttt caattgtgct ggtagctact atcagtttga ctaagaaaat
    20401 cttagaattc tttttagctc aagaagcaga aaaaatgatt gcaaaggaag cttaacacag
    20461 agctttcttt tttgctctta gagagttttt acaagcagct tataaaataa gaatttctga
    20521 atagacaaac tcaaaaaatg gctgggaaat ttaggaaaaa agcaagcacg attaaatttt
    20581 ttgtgttata atattttgtg aatagctatg cctatgttta gctatggaat aatacgaagt
    20641 gcgaaacttg gaagatagag aggaagcgat gtaatggcta gagaaggctt ttttacaggt
    20701 ctagatattg gaacaagctc tgtcaaggtg cttgtggccg agcagagaaa tggtgaatta
    20761 aatgtaattg gcgtgagtaa tgccaaaagt aaaggtgtaa aggatggaat tattgttgat
    20821 attgatgcag cagcaactgc tatcaagtca gccatttccc aagcggaaga aaaggcaggc
    20881 atttcgatta aatcagtgaa tgtcggcttg cctggtaatc ttttgcaggt agaaccaact
    20941 caggggatga ttccagtaac atctgatact aaggaaatta cggatcaaga tgttgaaaat
    21001 gttgtcaaat cagctttgac aaagagtatg acacctgacc gtgaagtcat tacctttatt
    21061 cctgaagaat ttattgtgga tggtttccaa gggattcgtg acccacgtgg catgatgggg
    21121 gttcgccttg aaatgcgtgg tttgctttat acaggacctc gtactatctt gcacaatttg
    21181 cgtaagacgg ttgagcgtgc aggtgttcag gttgaaaatg ttatcatttc accactagca
    21241 atggttcagt ctgttttgaa cgaaggggaa cgtgaatttg gtgctacagt gattgatatg
    21301 ggggcaggtc aaacgactgt cgctacaatc cgtaatcaag aactccagtt cacacatatt
    21361 ctccaagaag gtggagatta tgtaactaaa gatatctcca aggttttgaa aacctctcgc
    21421 aaattagcgg aaggcttaaa actgaattac ggggaagcct atccgcctct tgcaagcaaa
    21481 gaaaccttcc aagtagaggt tattggagaa gtagaagcag tcgaagtgac ggaagcctac
    21541 ttgtcagaaa ttatttctgc acgaatcaag cacatccttg aacaaatcaa gcaagaatta
    21601 gatagaaggc gtctattgga cctccctggt ggtattgtct taatcggtgg gaatgccatt
    21661 ttaccaggta tggttgagct tgctcaggaa gtctttggcg tccgtgtcaa gctttatgtt
    21721 ccaaatcaag ttggtatccg taatccagcc tttgcgcatg tgattagttt atcagaattt
    21781 gcgggtcaat taacagaagt taatcttttg gctcagggag cgataaaagg tgagaatgac
    21841 ttaagtcatc agccaattag ttttggtggg atgctgcaaa aaacagctca gtttgtacaa
    21901 tcaacgcctg ttcaaccagc tcctgctcca gaagtagagc cggtggcgcc tacagaacca
    21961 atggcggatt tccaacaagc ttcacaaaat aaaccgaaat tagcagatcg tttccgtggc
    22021 ttgatcggaa gcatgtttga cgaataaaga ggaaaaataa attatgacat tttcatttga
    22081 tacagctgct gctcaagggg cagtgattaa agtaattggt gtcggtggag gtggtggcaa
    22141 tgccatcaac cgtatggtcg acgaaggtgt tacaggcgta gaatttatcg cagcaaacac
    22201 agatgtacaa gcattgagta gtacaaaagc tgagactgtt attcagttgg gacctaaatt
    22261 gactcgtggt ttgggtgcag gaggtcaacc tgaggttggt cgtaaagccg ctgaagaaag
    22321 cgaagaaaca ctgacggaag ctattagtgg tgccgatatg gtcttcatca ctgctggtat
    22381 gggaggaggc tctggaactg gagctgctcc tgttattgct cgtatcgcca aagatttagg
    22441 tgcgcttaca gttggtgttg taacacgtcc ctttggtttt gaaggaagta agcgtggaca
    22501 atttgctgta gaaggaatca atcaacttcg tgagcatgta gacactctat tgattatctc
    22561 aaacaacaat ttgcttgaaa ttgttgataa gaaaacaccg cttttggagg ctcttagcga
    22621 agcggataac gttcttcgtc aaggtgttca agggattacc gatttgatta ccaatccagg
    22681 attgattaac cttgactttg ccgatgtgaa aacggtaatg gcaaacaaag ggaatgctct
    22741 tatgggtatt ggtatcggta gtggagaaga acgtgtggta gaagcggcac gtaaggcaat
    22801 ctattcacca cttcttgaaa caactattga cggtgctgag gatgttatcg tcaacgttac
    22861 tggtggtctt gacttaacct tgattgaggc agaagaggct tcacaaattg tgaaccaggc
    22921 agcaggtcaa ggagtgaaca tctggctcgg tacttcaatt gatgaaagta tgcgtgatga
    22981 aattcgtgta acagttgtcg caacgggtgt tcgtcaagac cgcgtagaaa aggttgtggc
    23041 tccacaagct agatctgcta ctaactaccg tgagacagtg aaaccagctc attcacatgg
    23101 ctttgatcgt cattttgata tggcagaaac agttgaattg ccaaaacaaa atccacgtcg
    23161 tttggaacca actcaggcat ctgcttttgg tgattgggat cttcgccgtg aatcgattgt
    23221 tcgtacaaca gattcagtcg tttctccagt cgagcgcttt gaagccccaa tttcacaaga
    23281 tgaagatgaa ttggatacac ctccattttt caaaaatcgt taagtaaatg aatgtaaaag
    23341 aaaatacaga acttgttttt cgagaagttg cagaggctag tctgagtgct catcgagaga
    23401 gtggttcggt ctctgtcatt gcagttacca agtatgtaga tgtaccgaca gcggaagcct
    23461 tgcttccgct aggtgttcat catatcggtg aaaatcgtgt agataagttt ctggaaaaat
    23521 atgaagcttt aaaagatcga gatgtgactt ggcatttgat tggtaccttg caaagacgta
    23581 aggtgaaaga tgtcattcaa tacgttgatt atttccatgc attggactca gtaaagctag
    23641 caggggaaat tcaaaaaaga agtgaccgag tcatcaagtg tttccttcaa gtaaatattt
    23701 ctaaagaaga aagcaaacac ggtttttcga gagaggaact gctggaaatc ttgccagagt
    23761 tagccagact agataagatt gaatatgttg gtttaatgac gatggcacct tttgaggcta
    23821 gcagtgagca gttgaaagag attttcaagg cggcccaaga tttacaaaga gaaattcaag
    23881 agaaacaaat tccaaatatg cctatgaccg agttaagtat gggaatgagt cgtgattata
    23941 aagaagcgat tcaattcggt tccacttttg ttcgtatagg tacatcattt tttaagtagg
    24001 agagaaccat gtctttaaaa gatagattcg atagatttat agattatttt acggaggatg
    24061 aggattcaag tctcccttat gaaaaaagag atgagcctgt gtttactcca gtaaattctt
    24121 cacaggaacc ggctctccca atgaatcaac cttcacagtc ggctggtaca aaagagaaca
    24181 atatcaccag acttcatgca agacaacagg aattggcaaa tcagagtcag cgtgcaacgg
    24241 ataaggtcat tatagatgtt cgttatccta gaaaatatga ggatgcaaca gaaattgttg
    24301 atttattggc aggaaacgaa agtatcttga ttgattttca gtatatgaca gaggtgcagg
    24361 ctcgtcgttg tttggactat ttggatggag cttgtcatgt tttagctgga aatttgaaaa
    24421 aggtagcttc taccatgtat ttgttgacac cagttaatgt tattgtaaat gttgaagata
    24481 tccgtttacc agatgaagat caacagggtg agttcggttt tgatatgaag cgaaatagag
    24541 tacgataatg atttttttaa ttcgtatgat ttataatgca gtggatattt actccctgat
    24601 tttggtagcc ttcgctgtca tgtcttggtt tccaggtgcc tacgaatcca gtttaggtcg
    24661 ttggattgta gcgttggtga aaccagtact tgctcccttg caacgcctgc ctttacagat
    24721 agcgggtctt gatttatctg tttgggtcgc gattgttttg gttcgatttt taggagaaaa
    24781 cctagtgcgt tttctggcga tgataggatg aataaaggga tttatcagca tttctccata
    24841 gaagatcgtc catttcttga caagggaatg gaatggataa agaaggtaga agatagctat
    24901 gctccttttt taactccttt tatcaatcct catcaggaga agctattaaa gattttggcc
    24961 aaaacctatg gtcttgcttg tagcagtagt ggggaattcg tctcgagtga gtatgttcga
    25021 gttttattat acccagatta tttccaacca gagttttcag attttgaaat atctctccaa
    25081 gaaattgtgt attccaataa atttgaacat ttaacgcatg ctaagatttt agggacagtc
    25141 atcaatcaat tagggattga acggaaactt tttggagata tcctagtaga tgaagaacgg
    25201 gcgcagatta tgattaatca gcagtttctt cttctctttc aagatggact aaagaaaatt
    25261 ggtcgtatac ctgtttcgct ggaggaacgt cctttcaccg agaaaataga taagctagaa
    25321 cagtatcgag aactggattt atctgtgtct agttttcgat tagatgttct tttatcaaat
    25381 gttttgaaac tatctaggaa tcaagcaaac cagttgattg aaaagaaact tgtccaagta
    25441 aattatcatg tggtagacaa atcagattac actgttcaag ttggagactt gattagtgtg
    25501 agaaaatttg gtcgcttgag attacttcaa gataagggac aaacgaaaaa agagaagaaa
    25561 aaaataaccg tccagttatt attaagtaag tgaggaatag aatgccaatt acatcattag
    25621 aaataaagga caagactttt ggaactcgat tcagaggttt tgatccagaa gaagtcgatg
    25681 aatttttaga tattgtggtt cgtgattacg aagatcttgt gcgtgcgaat catgataaaa
    25741 atttgcgtat taagagttta gaagagcgtt tgtcttactt tgatgaaata aaagattcat
    25801 tgagccagtc tgtattgatt gctcaggata cagctgagag agtgaaacag gcggcgcatg
    25861 aacgttcaaa caatatcatt catcaagcag agcaagatgc gcaacgcttg ttggaagaag
    25921 ctaaatataa ggcaaacgag attcttcgtc aagcaactga taatgctaag aaagtcgctg
    25981 ttgaaacaga agaattgaag aacaagagcc gtgtcttcca ccaacgtctc aaatctacaa
    26041 ttgagagtca gttggctatt gttgaatctt cagattggga agatattctc cgtccaacag
    26101 ctacttatct tcaaactagt gatgaagcct ttaaagaagt ggttagcgaa gtacttggag
    26161 aaccgattcc agctccaatt gaagaagaac caattgatat gacacgtcag ttctctcaag
    26221 cagaaatgga agaattacaa gctcgtattg aggtagccga taaagaattg tctgaatttg
    26281 aagctcagat taaacaggaa gtggaaactc caactcctgt agtgagtcct caagttgaag
    26341 aagagcctct gctcatccag ttggcccaat gtatgaagaa ccagaagtag ctccagtgca
    26401 tccgacaggt ccaacaccag ctacagaaac tgttgattca gcaccaggat ttgaagcacc
    26461 gcaagaatcc gttacaattt tataagaaac gatgtgagaa caatatctta tccttatatt
    26521 tccagcgagc aggagatggt gtgagtcctg cattccctaa cgataagatt atcctctcaa
    26581 aaactcaagt ctgaagctag taagatttga cgtttcccac gttacgggat aagagggaga
    26641 aagactaaat ctttttccga ataaaggtgg taccacgatt ttcgtccttt ttggaagtcg
    26701 tggtttttaa tttgttatta tttataaagg agataccatg aaactcaaag atacccttaa
    26761 tcttgggaaa acagctttcc caatgcgtgc aggccttccg accaaagagc cagtttggca
    26821 aaaggaatgg gaagatgcaa aactttacca acgtcgtcaa gaactaaatg aagggaaacc
    26881 gcattttgtc ttgcatgatg gccctccata cgcaaacgga aatatccacg ttggacatgc
    26941 catgaatcat atctcaaaag atatcatcat tcgttctaag tctatgtcag gttttaacgc
    27001 accttatatc ccaggttggg atactcatgg tctgccaatc gagcaagttt tggcaaagca
    27061 aggtgtgaag cgcaaagaaa tggacttggt tgagtacttg aaactctgtc gtgagtacgc
    27121 tctttctcaa gtttataaac aacgtgatga tttcaaacgc ttggggatgt caggtgactg
    27181 ggaaaattta tatgtgactt taactccaga ctatgaagca gcccaaatcc gtgtctttgg
    27241 tgagatggct aataagggtt atatctaccg tggtgccaag ccagtttact ggtcatggtc
    27301 atctgagtca gcccttgccg aagcggaaat tgaataccat gatttggttt cgacttcact
    27361 ttattatgcc aataaggtaa aagatggcaa aggtatccta gatacagata cttatatcgt
    27421 agtctggaca acaactccat ttaccatcac agcttctcgt ggtttgactg ttggtgcaga
    27481 tattgattac gttttggttc aacctgctag tgaaactcgt aagtttgtcg ttgctgcaga
    27541 attgttgact agcttgtctg agaaatttgg ctgggctgat gttcaagtgt tggcaactta
    27601 ccgtggtcaa gaactcaacc acatcgtaac agaacaccca tgggatacag ctgtagatga
    27661 gttggtaatc cttggtgatc acgttaccac tgactctggt acaggtatcg tccatacagc
    27721 ccctggtttt ggtgaggacg actacaatgt tggtattgct aatggtcttg aagtcgcagt
    27781 gactgttgac gaacgcggta tcatgatggc gaatgctggt cctgagtttg aaggtcagtt
    27841 ctacgacaag gttgtaccaa ctgttattga aaaacttggt aacctccttc tagcccaaga
    27901 agaaatctct cactcatacc catttgactg gcgtactaag aaaccaatca tctggcgtgc
    27961 agttccacaa tggtttgcct cagtttcaaa attccgccaa gaaatcttgg atgctattga
    28021 taaagttaaa ttccatacag aatggggtaa agtacgtcta tataatatga ttcgtgaccg
    28081 tggtgactgg gttatctctc gtcaacgtgc ttggggtgtt ccacttccaa tcttctatgc
    28141 agaagacggt acagctatca tgacagctga gactattgaa catgtggcgc aactctttga
    28201 agtacatggt tcaagcattt ggtgggaacg tgatgccaaa gacctcttac cagaaggatt
    28261 tacacatcca ggttctccaa atggggagtt caagaaagaa acagatatta tggatgtatg
    28321 gtttgactca ggttcatcat ggaatggtgt tttggtaaat cgtccaaatc tgacttatcc
    28381 agctgacctt taccttgaag gttctgacca ataccgtggt tggttcaact catcactcat
    28441 tacatctgtt gccaaccatg gcgtagcacc ttacaaacaa atcttgtcac aaggttttac
    28501 ccttgatggt aaaggtgaga agatgtctaa atcacttgga aataccattg ctccaagtga
    28561 tgttgaaaaa caatttggtg cagaaatctt gcgtctctgg gtaacaagtg ttgactcaag
    28621 caatgacgtg cgtatctcta tggatatttt gagccaagtt tctgaaactt accgtaagat
    28681 tcgtaacact cttcgtttct tgattgccaa tacatctgac tttaacccag ctcaagatgt
    28741 agtcgcttac gatgaacttc gttcagttga taagtacatg actattcgct ttaaccagct
    28801 tgtcaagacc attcgtgatg cctatgcgga ctttgaattc ttgacaatct acaaggcctt
    28861 ggtgaacttt atcaacgttg acttgtcagc cttctacctt gattttgcca aagatgttgt
    28921 ttacattgaa ggtgccaaat cattggaacg ccgtcaaatg cagactgttt tctatgacat
    28981 tcttgtcaaa atcaccaaac tcttgacacc aatccttcct cacactgcgg aagaaatctg
    29041 gtcatatctt gagtttgaag ctgaagactt cgttcaattg tcagaattgc cagaagctca
    29101 aacttttgct aatcaagaag aagtcttgga tacatgggca gccttcatgg acttccgtgg
    29161 acaagctcaa aaagccttgg aagaagctcg taatgcaaaa gttatcggga aatcgcttga
    29221 agcacacttg acagtttatc caaatgaagt tgtgaaaact ctactcgaag cagtaaacag
    29281 caatgtggct caacttttga tcgtgtcaga cttgaccatc gcagaagggc cagctccaga
    29341 agctgccctt agcttcgaag atgtagcctt cacagttgaa cgcgctgcag gtcaagtatg
    29401 tgaccgttgc cgtcgtatcg acccaacaac agcagaacgc agctaccagg cagtcatctg
    29461 tgaccactgt gcaagcatcg tagaagaaaa ctttgcggaa gcagtcgcag aaggatttga
    29521 agagaaataa ggttgaaaag tctaggcaaa attcaatttg agaagaaaag acaactaatt
    29581 ttatagtcta ttaaacgcat tgtatcacgt ttttgaatac ctgatatgat gcgtttttta
    29641 tttattttaa aaatttgcga ggtatgactt tttatactca acaagaatca aagagaaact
    29701 tagcaagcta acagtagtaa gataaaatag gaatttgata ttagggataa gattgctaaa
    29761 tagtgtaata tttttacaat aataaattta tatagttatt tttggtttct gaaaagtatt
    29821 atattttatt tcatattata caaattttta ttttataata tcagaaaata ctttttttaa
    29881 aagcaaatat gatacaattt tatttgaaaa aaataaaaaa ggagatttta ttatgaaatt
    29941 aaaaacactt gctttaatta gtg
//
LOCUS       DAVHTH010000024        29203 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.024, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000024 DAVHTH010000000
VERSION     DAVHTH010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 29203)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29203)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29203
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.024"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            complement(<1..227)
                     /locus_tag="VVR63_001091"
     CDS             complement(<1..227)
                     /locus_tag="VVR63_001091"
                     /inference="COORDINATES: protein motif:HMM:NF020296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HEU6129118.1"
                     /translation="MIDWDFADTCWEKDPRKYQYVAANYLKAMQSYLKETDLPKLEQL
                     VVTKSLWDTVDILDRVVGSLVYEHPELEEII"
     gene            complement(149..391)
                     /locus_tag="VVR63_001092"
     CDS             complement(149..391)
                     /locus_tag="VVR63_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HEU6129119.1"
                     /translation="MSLADLLEELEAAKDSKKARSMEAYMRHQFSFLGIAVPERNKLY
                     KNIFQKRKKQRLSIGILQTLAGKRILENTNMWLLTI"
     gene            complement(392..1024)
                     /locus_tag="VVR63_001093"
     CDS             complement(392..1024)
                     /locus_tag="VVR63_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU6129120.1"
                     /translation="MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALE
                     LRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIVTSYLDNEKIMPVLDAGAKGYML
                     KTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
                     ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQEEF"
     gene            complement(1038..2033)
                     /locus_tag="VVR63_001094"
     CDS             complement(1038..2033)
                     /locus_tag="VVR63_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU6129121.1"
                     /translation="MKKQAYVIIALTSFLFVFFFSHSLLEILDFDWSIFLHDVEKTEK
                     FVFLLLVFSMSMTCLLALFWRGIEELSLRKMQANLKRLLAGQEVVQVADPDLDASFKS
                     LSGKLNLLTETLQKAENQSLAQEEEIIEKERKRIARDLHDTVSQELFAAHMILSGISQ
                     QALKLDREKMQIQLQSVTAILETAQKDLRVLLLHLRPVELEQKSLIEGIQILLKELED
                     KSDLRVSLKQNMTKLPKKIEEHIFRILQELISNTLRHAQASCLDVYLYQTDVELQLKV
                     VDNGIGFQLGSLDDLSYGLRNIKERVEDMAGTVQLLTAPKQGLAVDIRIPLLDKE"
     gene            complement(2030..2728)
                     /locus_tag="VVR63_001095"
     CDS             complement(2030..2728)
                     /locus_tag="VVR63_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HEU6129122.1"
                     /translation="MRKFKIFLFIEACLLTGALILMVSEHFSRFLLILFLFLLLIRYY
                     TGKEGNNLLLVAATILFFFIVMLNPFVILAIFVAVIYSLFLLYPMMNQEKEQTNLVFE
                     EVVTVKKEKNRWFGNLHHFSSYQTCQFDDINLFRFMGKDTIHLERVILTNHDNVIILR
                     KMVGTTKIIVPVDVEVSLSVNCLYGDLTFFNQPKRALRNEHYHQETKDYLKSNKSVKI
                     FLTTMIGDVEVVRG"
     gene            complement(2805..3815)
                     /locus_tag="VVR63_001096"
     CDS             complement(2805..3815)
                     /locus_tag="VVR63_001096"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HEU6129123.1"
                     /translation="MTTNRKDEHILYALEQKSSYNSFDEVELIHSSLPLYNLDEIDLS
                     TEFAGRKWDFPFYINAMTGGSNKGREINQKLAQVAESCGILFVTGSYSAALKNPTDDS
                     FSVKSSHPNLLLGTNIGLDKPVELGLQTVEEMNPVLLQVHVNVMQELLMPEGERKFRS
                     WQSHLADYSKQIPVPIVLKEVGFGMDAKTIERAYEFGVRTVDLSGRGGTSFAYIENRR
                     SGQRDYLNQWGQSTMQALLNAQEWKDKVELLVSGGVRNPLDMIKCLVFGAKAVGLSRT
                     VLELVETYTVEEVIGIVQGWKADLRLIMCSLNCATIADLQKVDYLLYGKLKEAKDQMK
                     KA"
     gene            complement(3799..4806)
                     /locus_tag="VVR63_001097"
     CDS             complement(3799..4806)
                     /locus_tag="VVR63_001097"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HEU6129124.1"
                     /translation="MIAVKTCGKLYWAGEYAILEPGQLALIKDIPIYMRAEIAFSDSY
                     RIYSDMFDFAVDLRPNPDYSLIQETIALMGDFLAVRGQNLRPFSLEICGKMEREGKKF
                     GLGSSGSVVVLVVKALLALYDVSVDQELLFKLTSAVLLKRGDNGSMGDLACIVAEDLV
                     LYQSFDRQKVAAWLEEENLATVLERDWGFSISQVKPTLECDFLVGWTKEVAVSSHMVQ
                     QIKQNINQNFLSSSKETVVSLVEALEQGKSEKIIEQVEVASKLLEGLSTDIYTPLLRQ
                     LKEASQDLQAVAKSSGAGGGDCGIALSFDAQSTKTLKNRWADLGIELLYQERIGHDDK
                     S"
     gene            complement(4793..5746)
                     /gene="mvaD"
                     /locus_tag="VVR63_001098"
     CDS             complement(4793..5746)
                     /gene="mvaD"
                     /locus_tag="VVR63_001098"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HEU6129125.1"
                     /translation="MDREPVTVRSYANIAIIKYWGKKKEKEMVPATSSISLTLENMYT
                     ETTLSPLPANVTADEFYINGQLQNEVEHAKMSKIIDRYRPAGEGFVRIDTQNNMPTAA
                     GLSSSSSGLSALVKACNAYFKLGLDRSQLAQEAKFASGSSSRSFYGPLGAWDKDSGEI
                     YPVETDLKLAMIMLVLEDKKKPISSRDGMKLCVETSTTFDDWVRQSEKDYQDMLIYLK
                     ENDFAKIGELTEKNALAMHATTKTASPAFSYLTDASYEAMDFVRQLREKGEACYFTMD
                     AGPNVKVFCQEKDLEHLSEIFGHRYRLIVSKTKDLSQDDCC"
     gene            complement(5728..6606)
                     /gene="mvk"
                     /locus_tag="VVR63_001099"
     CDS             complement(5728..6606)
                     /gene="mvk"
                     /locus_tag="VVR63_001099"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HEU6129126.1"
                     /translation="MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVP
                     AESPWRLYEEDTLSMAVYASLEYLDITEACIRCEIDSAIPEKRGMGSSAAISIAAIRA
                     VFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDL
                     SAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEVAISQKDAEGLGQI
                     LSQAHLHLKEIGVSSPEADFWVETTLSHGALGAKMSGGGLGGCIIALVTNLTHAQELA
                     ERLEEKGAVQTWIESL"
     gene            complement(6728..7057)
                     /locus_tag="VVR63_001100"
     CDS             complement(6728..7057)
                     /locus_tag="VVR63_001100"
                     /inference="COORDINATES: protein motif:HMM:NF024736.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU6129127.1"
                     /translation="MIRKAYDTDLNDQEWAKIEPYFSKHRTYKWPKRVLVNETLYVTK
                     TGCQWRMLPHDFPLYLMVWSFFRRSMTTGWFQVNGRWYYAYSSGALAVNTTVDGYSVN
                     YNGEWAQ"
     gene            7720..8078
                     /locus_tag="VVR63_001101"
                     /pseudo
     CDS             7720..8078
                     /locus_tag="VVR63_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811282.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic-modifying protein"
     gene            7978..8448
                     /locus_tag="VVR63_001102"
     CDS             7978..8448
                     /locus_tag="VVR63_001102"
                     /inference="COORDINATES: protein motif:HMM:NF017000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6129128.1"
                     /translation="MTILLKLSSTIVYGEIYHYFLQRDTAKESILDYSFAHGYCEIAY
                     ALFAYSKVLEPSMFYNDLHTFHAELKKLLEKVTSNTENLGNLQLSWCEGISGIILYLC
                     MYDCDGNKDIISKYQEFVFNHHLKMMTGYCHGITSLLQTTVYNQNKLLMKKSNR"
     gene            8607..9839
                     /locus_tag="VVR63_001103"
     CDS             8607..9839
                     /locus_tag="VVR63_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEU6129129.1"
                     /translation="MKLFWTNNIYRQLLLNSCFSSFGDSIFYLAIINYVAQYNFAPLA
                     ILLISISEMVPLLSQLFLGILGDFQENRVKHALWIAKIKILLYAILTVFLVLSPFSLV
                     SVIMIVIINLISDTLSYLSAYMMNALYISVIKDDLHDAMGFRQSLMRVVHIVANLAGA
                     FLINVMSIQTISLINTLTFVIAFLGLYVIRHTLYEVEKRIEMSHTALSFKKYFQHLKQ
                     SLAVLLRLKDTVILLFLTTSMIAILDVSPRLIALRFIQQTLAQLSIGQLLAMLSIIIS
                     CGAILGNMTSSNLFKNIRFTHLLVFCEISLLALITSILCQAYIVIFMTSFISSTIIGI
                     LSPRLQAAVFAHIPSDKMGTVGSALSTVDILAPSLLSLLALSIASGVSVQLALIFLYL
                     ILIALIFCQWLVKFNTHN"
     gene            complement(9957..10955)
                     /gene="cbpJ"
                     /locus_tag="VVR63_001104"
     CDS             complement(9957..10955)
                     /gene="cbpJ"
                     /locus_tag="VVR63_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpJ"
                     /protein_id="HEU6129130.1"
                     /translation="MKLLKKMMPIALAVFFFGLLGTSTVFADDSEGWQFVQENGRTYY
                     KKGDLKETYWRVIDGKYYYFDSLSGEMVVGWQYIPFPSKGSTIGPYPNGIRLEGFPKS
                     EWYYFDKNGVLQEFVGWKTLEIKTKDSVGRKYGEKREDSEDKEEKRYYTNYYFNQNHS
                     LETGWLYDQSNWYYLAKTEINGENYLGGERRAGWINDDSTWYYLDPTTGIMQTGWQYL
                     GNNWYYLRSSGAMATGWYQEGTTWYYLDQPNGDMKTGWQYLGNKWYYLRSSGAMVTGW
                     YQDGLTWYYLNAGNGDMKTGWFQVNGKWYYAYSSGALAVNTTVDGYYVNYNGEWVR"
     gene            complement(11054..11743)
                     /locus_tag="VVR63_001105"
     CDS             complement(11054..11743)
                     /locus_tag="VVR63_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000518023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU6129131.1"
                     /translation="MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQ
                     TDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMILDHWEDLQEELEVVQRFAVSYIY
                     KPVFIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
                     REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIK
                     TVRGVGYTMQE"
     gene            complement(11755..13179)
                     /gene="gndA"
                     /locus_tag="VVR63_001106"
     CDS             complement(11755..13179)
                     /gene="gndA"
                     /locus_tag="VVR63_001106"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HEU6129132.1"
                     /translation="MTKANFGVVGMAVMGRNLALNIESRGYTVAIYNRSKEKTEDVIA
                     CHPEKNFVPSYDVESFVNSIEKPRRIMLMVQAGPGTDATIQALLPHLDKGDILIDGGN
                     TFYKDTIRRNEELANSGINFIGTGVSGGEKGALEGPSIMPGGQKEAYELVSDVLEEIS
                     AKAPEDGKPCVTYIGPDGAGHYVKMVHNGIEYGDMQLIAESYDLMQHLLGLSAEDMAE
                     IFTEWNKGELDSYLIEITADILSRKDDEDQDGPIVDYILDAAGNKGTGKWTSQSSLDL
                     GVPLSLITESVFARYISTYKEERVHASKVLPKPAAFNFEGDKAELIEKIRQALYFSKI
                     ISYAQGFAQLRVASKENNWNLPFADIASIWRDGCIIRSRFLQKITDAYNRDADLANLL
                     LDEYFLDVTAKYQQAVRDIVALAVQAGVPVPTFSAAITYFDSYRSADLPANLIQAQRD
                     YFGAHTYQRKDKEGTFHYSWYDEK"
     gene            complement(13255..14649)
                     /gene="mapZ"
                     /locus_tag="VVR63_001107"
     CDS             complement(13255..14649)
                     /gene="mapZ"
                     /locus_tag="VVR63_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mid-cell-anchored protein MapZ"
                     /protein_id="HEU6129133.1"
                     /translation="MSKKRRNRHKKEAQEPQFDFDEAKELTVGQAIRKNEEVEAGVLP
                     EDSILDKYVKQHRDEIEADKFATRQYKKEEFVETQSLDDLIQEMREAVEKSEASSEEV
                     PSSEDILLPLPLDDEEQGLDPLLLDDENPTEMTEEVEEEQNLSRLDQEDSEKKSKKGF
                     ILTVLALVSVIICVSAYYVYRQVARSTKEIETSQSTTANQSDVDDFNTLYDAFYTNSN
                     KTALKNSQFDKLSQLKTLLDKLEGSREHTLAKSKYDSLATQIKAIQDVNAQFEKPAIV
                     DGVLDTNAKAKSDAKFTDIKTGNTELDKVLDKAISLGKSQQTSTSSSSSSQTSSSSSS
                     QASSNTTSEPKPSSSNETRSSRSEVNMGLSSAGVAVQRSASRVAYNQSAIDDSNNSAW
                     DFADGVLEQILATSRSRGYITGDQYILERVNIVNGNGYYNLYKPDGTYLFTLNCKTGY
                     FVGNGAGHADDLDY"
     gene            complement(14662..15819)
                     /locus_tag="VVR63_001108"
     CDS             complement(14662..15819)
                     /locus_tag="VVR63_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HEU6129134.1"
                     /translation="MKKEFNLIATVAAGLEAVVGREVRELGYDCQVENGRVRFQGDVR
                     TIIETNLWLRAADRIKIIVGTFPAKTFEELFQGVFALDWENYLPLGARFPISKAKCVK
                     SKLHNEPSVQAISKKAVVKKLQKHYARPEGVPLMENGPEFKIEVSILKDVATVMIDTT
                     GSSLFKRGYRTEKGGAPIKENMAAAILQLSNWYPDKPLIDPTCGSGTFCIESVMIARK
                     MAPGLRRSFAFEEWNWISDRLIQEVRTEAAKKVERELELDIMGCDIDARMVEIAKANA
                     QAAGVAGDITFKQMRVQDLRSDKINGVIISNPPYGERLSDDAGVTKLYAEMGQVFAPL
                     KTWSKFILTSDEAFESKYGSQADKKRKLYNGTLKVDLYQYFGQRVKRQEVK"
     gene            complement(15904..16284)
                     /gene="rnpB"
                     /locus_tag="VVR63_001109"
     ncRNA           complement(15904..16284)
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="VVR63_001109"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            complement(16305..16646)
                     /gene="gpsB"
                     /locus_tag="VVR63_001110"
     CDS             complement(16305..16646)
                     /gene="gpsB"
                     /locus_tag="VVR63_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HEU6129135.1"
                     /translation="MTSIIFSAKDIFEQEFGREVRGYSKVEVDEFLDDVIKDYETYAT
                     LVKSLRQEIADLKEELTRKPQVSSAPSPSHPDPIDVAASSSMTNFDILKRLNRLEKEV
                     FGKQILDNTDL"
     gene            complement(16716..17243)
                     /locus_tag="VVR63_001111"
     CDS             complement(16716..17243)
                     /locus_tag="VVR63_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HEU6129136.1"
                     /translation="MATALVLGYSAFDLGLFSDKDPRLKLIKKAIRKDLEAMAADGVS
                     WLVFTGSLGFEYWVLEVAQEMKTEYGFQLATIFAFETHGENWNEGNQMKLSRFKQVDF
                     VKYAYPRYEHKGQLRDYQQFLLENTTSSYLFYDEENETKLAYFYQKMKNQEDYFIKRL
                     TFDQLNELAENFSEN"
     gene            17310..17906
                     /gene="recU"
                     /locus_tag="VVR63_001112"
     CDS             17310..17906
                     /gene="recU"
                     /locus_tag="VVR63_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HEU6129137.1"
                     /translation="MVNYPHKLSSQKRQPSLSQPKNFANRGMSFEKMINATNDYYLSQ
                     GLAVIHKKPTPIQIVRVDYPQRSRAKIVEAYFRQASTTDYSGVYNGYYIDFEAKETKQ
                     KRAIPMKNFHPHQIQHMEQVLAQQGICFVLLHFSSQQETYLLPAFDLIRFYHQDKGQK
                     SMPLGYIREYGYEIKAGAFPQIPYLNVIKEHLLGGKTR"
     gene            17903..20062
                     /locus_tag="VVR63_001113"
     CDS             17903..20062
                     /locus_tag="VVR63_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HEU6129138.1"
                     /translation="MNKPTILRLIKYLSISFLSLVIAAIVLGGGVFFYYVSKAPSLSE
                     SKLVATTSSKIYDNKNQLIADLGSERRVNAQANDIPTDLVKAIVSIEDHRFFDHRGID
                     SIRILGAFLRNLQSNSLQGGSTLTQQLIKLTYFSTSTSDQTISRKAQEAWLAIQLEQK
                     ATKQEILTYYINKVYMSNGNYGMQTAAQNYYGKDLNNLSLPQLALLAGMPQAPNQYDP
                     YSHPEAAQDRRNLVLSEMKNQGYISAEQYEKAVNTPITDGLQSLKSASNYPAYMDNYL
                     KEVINQVEQETGYNLLTTGMDVYTNVDQEAQKHLWDIYNSDQYVSYPDDDLQVASTVV
                     DVSNGKVIAQLGARHQASNVSFGTNQAVETNRDWGSAMKPITDYAPAIEYGVYDSTAT
                     MVNDIPYNYPGTSTPVYNWDRAYFGNITLQYALQQSRNVTAVETLNKVGLDRAKTFLN
                     GLGIDYPSMHYANAISSNTTESNKQYGASSEKMAAAYAAFANGGTYYKPMYIHKVVFS
                     DGSKKEFSNVGTRAMKETTAYMMTDMMKTVLTYGTGRGAYLPWLPQAGKTGTSNYTDE
                     EVENHIKNTGYVAPDEMFVGYTRKYSMAVWTGYSNRLTPIVGDGFLVAAKVYRSMITY
                     LSEDTHPEDWTMPDGLFRNGEFVFKNGARPIWTEPSTQQSSTAESSSSSSDSSTSQSS
                     STTPSTNNSTTTNPNNNTQQSNTTPDQQNQNPQPAQP"
     gene            complement(20229..25532)
                     /locus_tag="VVR63_001114"
     CDS             complement(20229..25532)
                     /locus_tag="VVR63_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001032503.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEU6129139.1"
                     /translation="MNKGLFEKRCKYSIRKFSLGVASVMIGAAFFGTSPVLADSVQSG
                     STANLPADLATALATAKENDGRDFEAPKVGEDQGSPEVTDGPKTEEELLALEKEKPAE
                     EKPKEDKHAAAKPETLKTVTPEWQTVEKKEQQGTVTIREEKGVRYNQLSSTAQNDNAG
                     KPALFEKKGLTVDANGNATVDLTFKEDSEKGKSRFGVFLKFKDTNNNVFVGYDKDGWF
                     WEYKSPTTSTWYRGSRVAAPETGSTNRLSITLKSDGQLNASNNDVNLFDTVTLPAAVN
                     DHLKNEKKILLKAGSYDDERTVVSVKTDNQEGVKTEDTPAEKETGPEVDDSKVTYDTI
                     QSKVLKAVIDQAFPRVKEYSLNGHTLPGQVQQFNQVFINNHRITPEVTYKKINETTAE
                     YLMKLRDDAHLINAEMTVRLQVVDNQLHFDVTKIVNHNQVTPGQKIDDERKLLSSISF
                     LGNALVSVSSDQTGAKFDGATMSNNTHVSGDDHIDVTNPMKDLAKGYMYGFVSTDKLA
                     AGVWSNSQNSYGGGSNDWTRLTAYKETVGNANYVGIHSSEWQWEKAYKGIVFPEYTKE
                     LPSAKVVITEDANADKNVDWQDGAIAYRSIMNNPQGWEKVKDITAYRIAMNFGSQAQN
                     PFLMTLDGIKKINLHTDGLGQGVLLKGYGSEGHDSGHLNYADIGKRIGGVEDFKTLIE
                     KAKKYGAHLGIHVNASETYPESKYFNEKILRKNPDGSYSYGWNWLDQGINIDAAYDLA
                     HGRLARWEDLKKKLGDGLDFIYVDVWGNGQSGDNGAWATHVLAKEINKQGWRFAIEWG
                     HGGEYDSTFHHWAADLTYGGYTNKGINSAITRFIRNHQKDAWVGDYRSYGGAANYPLL
                     GGYSMKDFEGWQGRSDYNGYVTNLFAHDVMTKYFQHFTVSKWENGTPVTMTDNGSTYK
                     WTPEMRVELVDADNNKVVVTRKSNDVNSPQYRERTVTLNGRVIQDGSAYLTPWNWDAN
                     GKKLSTDKEKMYYFNTQAGATTWTLPSDWAKSKVYLYKLTDQGKTEEQELTVKDGKIT
                     LDLLANQPYVLYRSKQTNPEMSWSEGMHIYDQGFNSGTLKHWTISGDASKAEIVKSQG
                     ANDMLRIQGNKEKVSLTQKLTGLKPNTKYAVYVGVDNRSNAKASITVNTGEKEVTTYT
                     NKSLALNYVKAYAHNTRRNNATVDDTSYFQNMYAFFTTGSDVSNVTLTLSREAGDEAT
                     YFDEIRTFENNSSMYGDKHDTGKGTFKQDFENVAQGIFPFVVGGVEGVEDNRTHLSEK
                     HDPYTQRGWNGKKVDDVIEGNWSLKTNGLVSRRNLVYQTIPQNFRFEAGKTYRVTFEY
                     EAGSDNTYAFVVGKGEFQSGRRGTQASNLEMHELPNTWTDSKKAKKATFLVTGAETGD
                     TWVGIYSTGNASNTRGDSGGNANFRGYNDFMMDNLQIEEITLTGKMLTENALKNYLPT
                     VAMTNYTKESMDALKEAVFNLSQADDDISVEEARAEIAKIEALKNALVQKKTALVADD
                     FESLDAPAQPDEGLENAFDGNVSSLWHTSWNGGDVGKPATMVLKEATEITGLRYIPRG
                     SGSNGNLRDVKLVVTDESGKEHTFAATDWPDNNKPKDIDFGKTIKAKKIVLTGTKTYG
                     DGGDKYQSAAELIFTRPQVAETPLDLSGYEAALAKAQKLTDKDNQEEVASVQASMKYA
                     TDNHLLTERMVEYFADYLNQLKDSATKSDAPTVEKPEFKLSSLASEQGKTPDYKQEID
                     RPETPEQILPATGESQSDTALFLAGVSLALSALFVVKTKKD"
     gene            complement(25833..27815)
                     /locus_tag="VVR63_001115"
     CDS             complement(25833..27815)
                     /locus_tag="VVR63_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU6129140.1"
                     /translation="MKSSKLFALAGVTLLAATTLAACSGSGSSAKGEKTFSYIYETDP
                     DNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPSMAEDWSVSKDGLTYTYIIRKDA
                     KWYTSEGEEYAAVKAQDFVTGLKYAADKKSDALYLVQESIKGLDAYVKGEIKDFSQVG
                     IKALDEQTVQYTLNKPESFWNSKTTMGVLAPVNEEFLNSKGDDFAKATDPSSLLYNGP
                     YLLKSIVTKSSVEFAKNPNYWDKDNVHIDKVKLSFWDGQDTSKPAENFKDGSLTAARL
                     YPTSASFAELEKSMKDNIVYTQQDSITYLVGTNIDRQSYKYTSKTSDEQKASTKKALL
                     NKDFRQAIAFGFDRTAYASQLNGQTGASKILRNIFVPPTFVQADGKNFGDMVKEKLVT
                     YGDEWKDVNLADSQDGLYNPEKAKAEFAKAKSALQAEGVTFPIHLDMPVDQTATTKVQ
                     RVQSMKQSLEATLGADNVVIDIQQLQKDEVNNITYFAENAAGEDWDLSDNVGWGPDFA
                     DPSTYLDIIKPSVGESTKTYLGFDSGEDNVAAKKVGLYDYEKLVTEAGDEATDVAKRY
                     DKYAAAQAWLTDSALIIPTTSRTGRPILSKMVPFTIPFALSGNKGTSEPILYKYLELQ
                     DKAVTVDEYQKAQEKWMKEKEESNKKTQEDLAKHVK"
     gene            complement(28245..28797)
                     /locus_tag="VVR63_001116"
                     /pseudo
     CDS             complement(28245..28797)
                     /locus_tag="VVR63_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007897432.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(28873..>29203)
                     /locus_tag="VVR63_001117"
     CDS             complement(28873..>29203)
                     /locus_tag="VVR63_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000927991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU6129141.1"
                     /translation="EEDWARMGLPITRKEISNWHIKASQYYLESLYNLLREKLLEQPL
                     LHADETSYRVLESDSHLTYYWTFLSGKAENQAITLYHHDQRRSGLVVQEFLGDYSGYV
                     HCDMLRQ"
BASE COUNT         8292 a         6645 c         5324 g         8942 t
ORIGIN      
        1 aagattattt cttctagttc agggtgttca tacaccaaac tccctactac tcgatctagg
       61 atatctaccg tgtcccacaa ggattttgtc acgactaact gctctagctt aggcaaatcg
      121 gtttccttta gataagactg cattgctttc aaatagttag cagccacata ttggtatttt
      181 ctaggatcct tttcccagca agtgtctgca aaatcccaat cgataatctt tgtttttttc
      241 gcttctggaa aatattttta tagagtttat ttctttcagg caccgcaata cctagaaaag
      301 aaaattgatg gcgcatatag gcttccatgg accttgcttt tttagagtct tttgctgctt
      361 ctagctcctc aagtaaatct gctaaactca tctaaaactc ctcttgcccc accaaatggt
      421 gctgaaaggc atagacagcc gcctgggtac gatcgctgac ttcaagtttg gcaagaatat
      481 tggacacgtg ggtcttgacc gtcttgagag agataaagag gtcatctgcg atgcgctgat
      541 tttcgtagcc cttggcgatg agttggagaa catctcgctc acgcgcagtc aattcttcat
      601 gaagttccat atgattgcgg tggtattcaa ccttcttgct aacctcttgc tcaatggcca
      661 gctcgccagc agctacctta ctgacggcat gaagcaattc atctgcacta gaagtcttga
      721 gcatatagcc tttggcacca gcatctaaga ctggcatgat tttttcattg tccaaataag
      781 aggtcacaat caaaatcttg gcttcaggcc attctttaag gattgctaag gtcgcgtcaa
      841 ttccattcat ctcaggcatg acaatatcca tgacaatgac atctggacgc agttccaagg
      901 ccaagtcaat cccttgagac ccgttggacg cctcacccac aacttctaca tcgtcttgga
      961 ggtcaaagta gcttttcaaa cccaaacgga ccatttcatg gtcatctact agtaaaattt
     1021 tcatctttac tcctttatca ttccttatct aacaggggaa tacggatatc aactgccagc
     1081 ccttgcttgg gagctgttaa taactgaacc gtccctgcca tatcttcaac ccgctccttg
     1141 atatttcgca gtccataact caagtcgtct aagctcccta actggaaacc aatcccattg
     1201 tccaccacct tcagttgcaa ttcaacatct gtctgataga ggtagacatc taggcaagat
     1261 gcctgggcat ggcggagggt attgctaatc aactcttgca ggatacggaa gatatgctcc
     1321 tcgattttct taggcaattt cgtcatattc tgcttgagac taaccctaag atcactcttg
     1381 tcctcaagct cttttaagag aatctgaatc ccttctatca agctcttctg ctccagttca
     1441 actggtcgca aatgcaagag caaaacccgc aaatccttct gggcagtttc taaaatagct
     1501 gtgacactct gcaactggat ctgcatcttt tctctatcca atttcaaagc ctgctgactg
     1561 atacccgata aaatcatgtg ggccgcaaac aactcctgac tgactgtatc gtgcaaatcc
     1621 cgagcaattc gcttccgttc cttctcgatg atttcctctt cctgagcaag gctctgattt
     1681 tcagcttttt gaagagtctc tgtcaaaagg ttaagtttac ctgataagga cttgaaactg
     1741 gcatccaaat ctggatctgc aacctgaacc acttcttgcc ctgctaataa acgcttgaga
     1801 ttagcctgca tttttcttag agaaagctct tcgatccctc gccaaaacag ggctaagaga
     1861 caggtcatgg acatgctgaa aaccaacaat aaaaagacaa atttttctgt tttttcgaca
     1921 tcgtgcaaaa agatagacca gtcaaaatca agtatttcca gcaagctgtg ggagaaaaaa
     1981 aagacaaata ggaaggaggt gagagcaata atgacatagg cttgtttttt catcctctaa
     2041 ccacctccac atcaccaatc atagtggtca agaaaatctt gacactcttg ttactcttga
     2101 gatagtcttt tgtttcttga tgatagtgtt cattgcggag ggctcgcttg ggctggttga
     2161 aaaaagtcaa atccccatag agacagttaa cgctgagact gacttccaca tctacaggta
     2221 cgatgatttt ggtcgttcct accatctttc tgaggataat gacattgtca tgattggtta
     2281 agatgaccct ctccagatga atagtgtcct tgcccatgaa gcgaaagaga ttgatatcat
     2341 cgaattggca agtctggtag cttgaaaaat gatgaagatt tccaaaccaa cgatttttct
     2401 ccttcttaac cgtcacgacc tcttcaaaaa ccaaattggt ctgctctttt tcctggttca
     2461 tcatcgggta aagaagaaag aggctataga taaccgcaac aaaaatagct agaatcacaa
     2521 aaggattgag cataacgatg aaaaagaaga gaatggttgc cgctactaaa agaagattat
     2581 ttccctcttt accagtgtag tagcgaatca aaagcaaaaa gaggaatagt atcagcagaa
     2641 aacgcgaaaa atgctctgat accatcaaaa tcagagctcc tgtcagaaga caggcttcga
     2701 taaataaaaa gattttaaat tttctcatag gttcatcctc tcccttctat tttatcacaa
     2761 ttcaaaaaag tcacctcagt ctgaggatgg aaaaaaggcg ctggttacgc ctttttcatc
     2821 tgatcctttg cttcttttaa ttttccataa agaagatagt ctactttttg tagatctgct
     2881 atggtggcac agttaaggga acacataatc aagcgtaggt ctgctttcca gccttggaca
     2941 atgccaatca cttcttcaac tgtgtaggtt tcaaccaatt ccagaacggt tcgtgacaat
     3001 cccacagcct tagcaccaaa aaccaagcac ttaatcatat ccagcggatt ccgaacccct
     3061 ccactaacca agagttcgac cttatctttc cattcttggg cattgagaag ggcctgcatg
     3121 gtagactgac cccattgatt gaggtaatca cgctggccac tacgacggtt ttcgatatag
     3181 gcaaagctgg tgccaccacg acccgatagg tccactgtac gaacaccgaa ttcataggct
     3241 ctttcgattg tcttggcatc cattccaaag cccacttcct tgaggacaat aggaacggga
     3301 atttgcttgc tataatctgc tagatgcgat tgccagcttc taaacttcct ttctccctcg
     3361 ggcatgagta attcctgcat gacattgaca tgcacttgca atagaacagg attcatctct
     3421 tctacagtct gaagtcctaa ctcgacaggc ttgtccaatc caatattggt tccaaggagg
     3481 agattgggat gactagactt gacagaaaaa gaatcatccg ttggattttt gagggctgcg
     3541 ctataagaac ccgttacaaa taaaatacca caggattccg ccacctgagc cagcttttga
     3601 ttgatttctc ttcccttatt acttccacca gtcatggcat tgatataaaa aggaaagtcc
     3661 cactttcgac cagcaaactc tgtcgaaaga tcgatttcat ccagattgta aagaggcaag
     3721 gaagaatgaa tcagctccac ctcatcaaag ctattatagg aacttttctg ctcaagggca
     3781 tagaggatat gctcgtcctt acgatttgtc gtcatgtcct atcctttctt gatataagag
     3841 ctcaatcccc agatcggccc aacgattttt taaggttttg gttgattgcg catcaaaact
     3901 cagggcgatg ccacagtcac caccaccagc accactactc ttggcaacgg cctgcaaatc
     3961 ttgactggct tctttcaact gtctaagcaa aggcgtgtaa atatctgtac tcaagccttc
     4021 taaaagcttg ctggctactt ctacttgctc gataatcttt tctgatttcc cctgttccaa
     4081 ggcttcgacc aaagaaacca ccgtttcttt tgaggaactt aaaaaatttt gattgatatt
     4141 ttgcttgatt tgctggacca tgtgactcga tacagccact tccttggtcc atcccactaa
     4201 gaaatcacat tctaaagttg gtttcacttg tgaaattgaa aagccccaat cacgctccag
     4261 aactgtcgcc aagttttctt cttctaacca agcagccacc ttctggcgat caaatgactg
     4321 gtagagaacc aaatcctctg ccacaataca ggcaaggtcg cccatggaac cattgtctcc
     4381 tcgcttgagc aagacagcgc tagtcagctt gaacaagagc tcctgatcaa cagaaacatc
     4441 atacagagcc agtaaagcct tgacaaccaa gacaacgacg ctgccactag aacctagacc
     4501 aaactttttc ccttctcgtt ccattttgcc acagatttct agagaaaaag gtcttaaatt
     4561 ctgaccacga acagcgagga agtctcccat caaagcaatc gtttcttgaa tcaagctgta
     4621 gtcaggatta ggccttaagt ccactgcgaa atcaaacata tctgaataga tacggtagct
     4681 gtcagaaaaa gcaatctcag ccctcatata gatgggaata tcctttatca aagctaactg
     4741 ccctggctct aaaatagcat attcacctgc ccaatagagt tttccgcaag ttttaacagc
     4801 aatcatcttg actcaaatcc tttgtttttg acacaatcaa gcgataacga tgaccgaaaa
     4861 tttctgataa atgctccaag tctttctcct gacagaagac cttaacattg ggaccagcat
     4921 ccatggtaaa gtagcaggcc tctcctttct cacgaagctg gcgaacaaag tccatagcct
     4981 cataagaggc atccgtcaga taagaaaagg ctggactagc agtctttgtc gtagcatgca
     5041 tagccagggc atttttctcc gttaattctc caatcttggc aaaatcattt tccttgagat
     5101 aaatcagcat atcctgatag tccttctcag actgacgaac ccagtcgtca aaagtcgtcg
     5161 aggtttccac acaaagtttc atcccgtcac ggctagagat tggttttttc ttgtcctcta
     5221 gcaccaacat aatcatagct agtttcaagt ctgtctctac agggtaaatt tctccactat
     5281 ccttatccca ggctcctagt ggtccataaa aactccgaga agaagagcct gaggcaaatt
     5341 tggcttcctg tgccaactga cttctatcca atccaagctt gaaataagca ttacaagcct
     5401 tgaccagggc ggacaaacca ctagaacttg aggacaggcc cgctgcagta ggcatattgt
     5461 tttgagtatc gatacggaca aagccctcac cagctggacg ataacggtca ataatcttac
     5521 tcatcttggc atgctcgacc tcattttgta gctgaccatt gatgtaaaat tcgtcagctg
     5581 ttacattggc tggtaaaggc gacaaggtcg tctctgtata catattttcc aaagttagag
     5641 aaatactgct agtagcaggc accatctctt tttctttttt ctttccccaa tatttgataa
     5701 tagcaatatt tgcgtaggaa cgtactgtta caggctctct atccatgtct gaacagctcc
     5761 tttctcttct aatctttctg ctagttcttg tgcgtgtgtc aaattggtta ccaaggctat
     5821 gatacaacct cctagcccac caccgctcat cttggcaccc agagcaccat ggctaagagt
     5881 cgtttcaacc caaaagtctg cctcagggct actgactcca atttctttta aatgtaaatg
     5941 cgcttgactg aggatttgtc ccagtccttc agcatctttt tgtgaaatcg caacttctgc
     6001 ttgctgggtt aattctccca aggcatgcaa aaacggtagg gcatccttgc ccttattttg
     6061 aaccacttgg atggcttcac gagtatgacc ataaacaccc gtatcggcaa tcaccaaata
     6121 ggcggataaa tccatctcaa gttctgtaaa tcctacgttc ttgataaagc gaataggttg
     6181 gtcactgaga caggtcttag catccaaacc actaggattc atatgggcaa tcatttcagc
     6241 tcgattgacc aagatttcta gtacatcatg aggcagatca gcctgatagt agtcaaatac
     6301 cgcacgaatg gccgctatgc tgatagccgc tgacgaaccc atcccccgtt tctcagggat
     6361 agccgagtca atctcacaac gaatgcaggc ttctgtgata tccaaatact ccagtgaggc
     6421 ataaaccgcc atggacaagg tatcctcctc ataaaggcgc caaggactct ctgcaggaac
     6481 taccttacag gtcacctcca cctccaaaag aggcagggaa atggcaggat aaccgtaaac
     6541 gaccgcatgt tcccctatta aaattatctt actatgtgcc tgaccgacac caactttttt
     6601 tgtcattttt tccttttact agacgaaaaa acgtcttatt tttcatacaa gtattaattc
     6661 tttcctatct attttattat attttcacaa aaaaagcgat tgtttccatt cacaatcgct
     6721 tctttcatta ttgagcccat tcgccattat agttgacaga atagccatct acggtcgtat
     6781 tcactgccaa ggcacctgag ctataagcgt agtaccatct gccattgacc tggaaccaac
     6841 ctgtcgtcat agaacgacga aagaaactcc ataccattaa gtaaagagga aagtcgtgag
     6901 ggagcatgcg ccattgacaa cctgttttag tgacgtacaa agtctcatta acaagtactc
     6961 gtttcggcca tttataggtg cggtgtttgg agaaataggg ttcaatcttc gcccattctt
     7021 gatcgtttaa atcagtatca tatgctttac gtatcataac tctagtttaa catttttttg
     7081 tgaatacagg ttctaaataa tcgaccacga aaatttctta agtggaaaac gccttatgaa
     7141 gtatgctacg ggaaacttat gcacttaatt tgacaattca agatgtaaaa atatatacta
     7201 tagtagattg aaactagaat agtacacctc tacttctaaa acatttttag aaatcgattt
     7261 gactgtcctg atcgatttgt cctgttatta tttcatttta ctataatatt tgataagtta
     7321 tcctaaaagt gttattatgt tgttgtgtta tagattgatt gaatctaact aaaggatcct
     7381 attcaattac tagaactatc acatactcaa ggtcagctca cagatgagca actattttgg
     7441 ttacaatgtc tactaaattt aagtcaaaca aataatttag tcaaaattaa aaaaatagag
     7501 gaacataaat atgattacaa aacagaatgt aatagtgttc tacgattttt actagataaa
     7561 actgtaaatt ctgaaggaag gatcacttct tcaacagaat ttggaaattt cgtaagtaat
     7621 ttatcattcc aacacggaat agctggacta ctgtttcctc taaataaatt gtacccccca
     7681 gaactggatt ctaaaatact ctctatcatc aagaaggcag tgacaattag aacgacacac
     7741 acatatgaat atcaatactc actgctattt ggtgatgcag gctatctttt ggtgatgcag
     7801 gctatctatg gttactccta catttatttt ctatcagtaa aaatcaatac tatctacaat
     7861 tagcaaacgt caccgctaag aaattaatag agaattatga tactctagag gaaatagact
     7921 ttgcattggg aaaatctggt gtcctattat cattaataaa atactatcaa tttaccaatg
     7981 acaatactct taaaactttc atccacaata gtatatgggg aaatttatca ttatttccta
     8041 caaagagata cagccaaaga aagcatttta gactatagct ttgctcatgg atattgtgaa
     8101 attgcatatg ctttatttgc ctattctaaa gtcttagaac cttctatgtt ctataatgat
     8161 ctccatacat tccatgctga attaaaaaaa ttattagaaa aagttacttc taatactgaa
     8221 aatttaggaa atttacaact ttcttggtgc gaaggaattt ccggaataat cttatatctt
     8281 tgtatgtacg attgtgacgg aaacaaagat attattagta aatatcaaga atttgttttt
     8341 aaccatcatc taaaaatgat gacaggatat tgccacggaa taactagctt actacaaacc
     8401 actgtctaca atcaaaacaa attactgatg aaaaaatcca acaggtaatt ttagcatgtt
     8461 ctgaacgaga tgatcacggt ttactgatgt ttcaaggaga tagtggtaaa acagatttgt
     8521 ttgacttcgg aataggaagc atggggtata ttggtgtcta ttaaataata aattcccatt
     8581 cgatgtgcag acataaggag aaaagtatga aattattttg gacaaacaac atatatagac
     8641 agttgctgct aaacagctgt ttttcatcat tcggcgacag tattttctac ctcgccatta
     8701 tcaattatgt ggctcagtac aatttcgctc cgctagcgat tttactgatt tccatttcag
     8761 agatggttcc cctactatcg caactctttc tcgggattct aggagatttt caagaaaata
     8821 gagtcaaaca cgcactctgg attgccaaaa tcaaaatcct gctctacgct attttgacag
     8881 tatttctcgt cttgtcgccc ttttcattag tttcagtcat tatgattgtc atcatcaacc
     8941 tcatctctga caccttgagc tacctgtctg cctacatgat gaacgccctc tacatcagtg
     9001 taattaagga cgacctgcat gatgccatgg ggttcaggca gtctctgatg agggttgtcc
     9061 acattgtcgc caatctggct ggcgcattcc ttatcaatgt tatgagtatt caaactattt
     9121 cccttatcaa cactctgact tttgtcattg cctttttggg tctgtatgtt attagacata
     9181 ccttgtatga ggttgaaaaa aggattgaaa tgtcacatac agcactgagt tttaagaaat
     9241 attttcaaca tcttaaacag tcgctggctg tgctcctgag gttaaaagat accgtcatac
     9301 tactgtttct gacgaccagt atgattgcca tcttggatgt gtcccctcgg ctgattgccc
     9361 tccgcttcat ccaacagaca ctagcacaac tgagcattgg gcaactcctc gccatgctct
     9421 ccatcatcat ttcttgtgga gctatccttg gcaatatgac cagcagtaat ctatttaaaa
     9481 atatccgttt cacgcacctc ttggttttct gtgagatttc cctattggct ctaataacta
     9541 gtatcctttg tcaagcctat atcgtaattt tcatgaccag tttcatcagt tctacgatta
     9601 tcggcattct cagccctcgc ctacaagcag ctgtctttgc ccatatcccc agtgacaaga
     9661 tggggacggt gggctctgct ctgagcacag tagacattct cgccccgtcc ctgctctccc
     9721 tattagccct gtccatagca tcgggcgttt cggtgcagtt agcattgata tttttgtatc
     9781 ttattttgat tgctcttatc ttttgtcaat ggttagtcaa gttcaacact cataactaac
     9841 gaaaaagcat gtgtagattt cacatgcttt taatctcccc aatcgtcagg tcaagtacaa
     9901 caaagtcact tctttgatta agcgagtgtt ctaatataat tataagcgcc ctgtcattac
     9961 cgaacccatt cgccattata gttgacgtag tagccatcta cggtcgtatt caccgccaaa
    10021 gcacctgagc tataagcata gtaccatttg ccattgacct ggaaccaacc tgtcttcatg
    10081 tctccattac ctgcatttag gtagtaccaa gttaaaccat cttgatacca gccagttacc
    10141 attgctcctg atgaacggag gtagtaccac ttgttaccaa ggtattgcca tcctgttttc
    10201 atatcaccat ttggctggtc taaataatac caagtggtac cttcctgata ccagccagtg
    10261 gccattgctc ctgatgaacg gaggtagtac cagttattac ctagatattg ccatcctgtt
    10321 tgcataatac cagttgttgg atctaaatag taccaagtcg aatcatcgtt tatccacccc
    10381 gcacgtcttt caccaccaag gtagttttct ccattaattt ccgtcttagc tagataatac
    10441 cagttagact gatcataaag ccaacctgtc tctaaagaat gattttgatt aaagtaatag
    10501 ttcgtataat aacgcttctc ttctttatct tctgaatctt cacgtttttc cccgtacttt
    10561 cttccaacac tgtctttagt tttaatctct aatgttttcc aaccaacaaa ctcttgtagc
    10621 actccatttt tatcgaagta gtaccactct gactttggaa aaccttctaa tctgatacca
    10681 tttgggtaag gaccaattgt actaccttta gatggaaacg ggatatattg ccagccgaca
    10741 accatctctc cagatagaga atcaaaataa tagtacttac catcaatcac tcgccagtag
    10801 gtttctttga ggtccccctt tttgtagtag gttcttccgt tttcttggac aaactgccat
    10861 ccttcagaat catctgcaaa tactgtactg gtccctagca aaccaaagaa aaagactgct
    10921 aatgcgattg gcatcatttt tttcaaaagc ttcattttat atatcctcct aaaacgattg
    10981 tagtaaaaac tagattgtat gtcaatatat aaaaactcct caaaaaagca gttacacaac
    11041 tgcaactgct tttctattct tgcatggtgt aaccaacacc acgcacggtt ttaatgtagc
    11101 ttttttggcc tttaacatca agcttgctcc gtagatagcg gatatagaca tctacgatat
    11161 ttgtctcggt cgcactttca tacttccaaa cactttccaa caattgctca cgagtcaata
    11221 ctttcttgct tcccataagt gtcgccaaaa ggtcatactc acggcgggtc agagcaatca
    11281 tctcttcacc acgataaacc gtgtgatgtt caacatctat cctaagattg cggtaggtcc
    11341 ttggaacttt catcagactg cagtgttgat caatgaagtc ccgacctcgg aagattgccg
    11401 aaatacgcgc taccagattt tcgataaaga ctggcttata gatgtatgaa actgcaaaac
    11461 gctgaacaac ttccagctct tcttgcaagt cttcccaatg atctaaaatc atgatgactg
    11521 aggcaggttt agttcgactc aatttttctg caaaatcctg agccatcata tctcccagat
    11581 taacgttcaa taaaatcaaa tcatagtctg tctgaagagc catggaaagg gctttttgcc
    11641 cctcctctac cagatcaacc cgatactgct ctttctggag ttccaaactt aaaaaatgag
    11701 ctagatttcg ttctttctca agtaataaaa tccgtttccc catggctgac ctacttattt
    11761 ttcgtcatac caagagtagt ggaaggttcc ttctttgtct ttacgttggt aagtgtgagc
    11821 accaaagtag tcacgttgtg cttggatcaa gttagccgga aggtcagctg aacggtagct
    11881 atcaaagtaa gtaatagctg ctgagaaagt tggcactggc acaccagctt gaaccgcaag
    11941 agctacgata tcacgcactg cttgttgata cttagcagta acatccaaga agtactcgtc
    12001 caaaagaagg ttggcaagat ctgcatcgcg gttgtaagca tctgtaatct tttgcaagaa
    12061 acgagaacgg atgatacagc catcacgcca gatagatgcg atatctgcaa atggcaagtt
    12121 ccagttgttt tctttagagg ctacacgcaa ttgagcaaat ccttgtgcgt atgaaatgat
    12181 ttttgagaag taaagggctt gacggatttt ttcaatcaat tcagccttgt ctccttcaaa
    12241 gttgaaggca gctggttttg gaagcacctt gctagcatgt acacgttctt ctttgtaagt
    12301 tgaaatgtag cgtgcaaaca ctgactcagt aatcagtgac aatggtacac caaggtcaag
    12361 agatgattgg ctcgtccatt taccagttcc cttgttacct gcagcatcaa ggatgtagtc
    12421 tacgattggt ccatcttggt cttcatcgtc tttacggctc aagatatcag ctgtgatttc
    12481 gatcaagtag ctatccaatt cacccttgtt ccactcagta aagatttcag ccatatcctc
    12541 tgcagaaagg cctagcaagt gttgcatcaa gtcatagctt tctgcgatca attgcatatc
    12601 accgtactcg ataccgttgt gaaccatttt cacatagtgg ccagctccat caggaccgat
    12661 ataagtcaca catggtttgc catcttctgg tgctttagct gagatttctt caagaacatc
    12721 cgaaaccaat tcgtaggcct ctttttgtcc accaggcatg atagaaggac cttcaagggc
    12781 acctttttca ccaccagaaa ctccagtacc gataaagttg atacctgagt ttgccaattc
    12841 ttcattacga cggatggtat ctttgtagaa agtgtttcct ccgtcaatca agatatcacc
    12901 tttgtcaagg tgtggaagaa gggcttggat agtagcatct gtaccaggtc cagcttgaac
    12961 catcagcatg atacgacgag gtttttcgat tgagtttaca aaactttcaa cgtcatagct
    13021 tggtacaaaa ttcttttcag gatggcaagc aatcacatct tccgtttttt ctttactacg
    13081 gttgtagata gcaactgtgt aaccacgtga ttcaatatta agggcaaggt tacgacccat
    13141 tacggccata cctacgacac caaagttagc ttttgtcatt tgacactcct cttgtttcat
    13201 ttgttttatt ttatcatttt tacttttgaa aagaaagaat tttgtaacga ctgcttagta
    13261 gtccaagtca tccgcatgac cagcgccatt tccgacaaag tagcctgtct tacagttaag
    13321 ggtaaagaga taggttccat ctggcttata gaggttgtaa taaccattgc cgttaacgat
    13381 attgacacgt tcaaggatat attggtctcc agtgatatag ccacgtgaac gtgaagttgc
    13441 tagaatttgt tccaaaacac catccgcaaa atcccaggca gagttattac tatcatcaat
    13501 agcagactga ttataggcaa cacgactggc acttctttga acagcaaccc ctgcactcga
    13561 gagacccata ttgacttcac tgcgactact tctagtctca tttgaactac ttggttttgg
    13621 ctcactagtc gtatttgaac ttgcttgact tgaacttgag ctgctagttt gacttgaact
    13681 tgagctagaa gtacttgttt gctggctctt accaagactg atagccttat ctagcacttt
    13741 atcaagctcc gtatttccag ttttaatatc cgtaaattta gcatccgatt tggctttggc
    13801 attggtatcc aacacaccat ccacaatagc tggtttttca aattgtgcat tgacatcttg
    13861 aatagccttg atttgcgttg ctagactatc atatttagat ttggcaagcg tatgttcacg
    13921 actaccttcc agcttatcaa gtaaagtctt gagttgactc agtttatcaa actggctatt
    13981 tttcaaagcc gttttattgc tatttgtgta aaaggcgtca taaagtgtat taaaatcatc
    14041 cacatccgac tgattggctg tagttgattg agaagtttca atttccttgg tcgaacgagc
    14101 cacttgacga tagacataat aagcactgac acaaataatt actgatacaa gcgccaaaac
    14161 ggtcaaaata aagccttttt tacttttctt ttctgagtcc tcttgatcca gacgagaaag
    14221 gttttgctcc tcttccactt cttcagtcat ttctgttgga ttttcatcat ctagcaatag
    14281 aggatccaag ccttgctcct catcgtccag aggcaagggt agtaagatgt cttcagaaga
    14341 tggaacttcc tccgaagaag cttctgactt ctctacagcc tcacgcatct cttgaattaa
    14401 atcatccaga ctctgagttt caacgaactc ctcttttttg tattgacgag tcgcaaactt
    14461 atccgcctca atttcatctc tgtgttgctt aacatacttg tccaaaatgg aatcctcagg
    14521 caagactcct gcttccactt cttcattttt acgaatagct tgaccaactg ttagctcttt
    14581 tgcttcatca aaatcaaatt gcggttcttg agcttctttt ttatgacgat ttcgtctttt
    14641 tttactcatg agtatccctt tctattttac ctcttgccgt ttgacacgct gaccaaaata
    14701 ttgatataaa tccactttca aggttccgtt gtataactta cgcttcttat ctgcttggct
    14761 accatacttg ctttcaaaag cttcatcact agtcaggata aatttgctcc aagttttcag
    14821 cggtgcaaat acttgcccca tctcagcata gagcttggtc acccctgcat catctgacaa
    14881 acgttcacca taaggcggat tggaaatgat tactccattg attttatcgg aacgtaaatc
    14941 ctgcacgcgc atctgcttaa aagtaatgtc tcctgcaaca ccagctgcct gagcattggc
    15001 cttagcaatt tccaccatgc gagcatcaat atcacagccc atgatatcca gctcaagctc
    15061 acgttctact tttttagccg cttctgtgcg cacttcttga atcaagcgat cgctgatcca
    15121 gttccattcc tcaaatgcaa aagagcgacg aagacctggc gccatctttc tagcaatcat
    15181 aactgactca atacagaaag tccccgaacc acaggtcgga tcaatcaaag gcttgtctgg
    15241 gtaccagtta gaaagttgta aaatggctgc tgccatattt tccttgatag gagcgccacc
    15301 tttttcggta cgataaccac gtttaaagag gctagacccg gtcgtatcaa tcatgacagt
    15361 tgccacatct ttgagaatag agacctcaat cttaaactct gggccattct ccatcagagg
    15421 aaccccttct gggcgagcat agtgtttctg caatttcttg acaacagctt tcttagaaat
    15481 agcctgaaca ctaggctcat tgtgaagttt ggacttaaca catttagctt ttgaaatcgg
    15541 gaaccgagct ccaagtggta aataattttc ccaatctaaa gcgaaaactc cctgaaacag
    15601 ctcttcaaaa gtcttagctg ggaacgttcc tacgataatc ttgatacgat ctgctgcccg
    15661 aagccacagg ttggtttcga taatagttct cacgtctcct tgaaaacgaa cacgaccatt
    15721 ttcaacctga caatcgtagc ccaactctcg cacttctcgt cccacaacag cttcaagacc
    15781 tgctgccaca gttgcaatta aattaaattc ttttttcatg ttacagtctt gcaagacctt
    15841 tctatatgtc cactttaaaa aatgaggttg agaaaatttc tcagccccaa cctatatgca
    15901 attttctata agccatgttt tgttccagaa gtgactagga ccacttcctt cgataatcat
    15961 ctgtctacca ctagcagctc tagctgatag cagtcagaat actacgttcg tttccgcgta
    16021 ctccatgccc cgaccaaaat ttgggttgct agcttgaggg gtttaccgcg ttccactctc
    16081 tctgtttcca gaaagactcc gtcactgtgg cactttcaag cctactctgg cctatccaag
    16141 gacttagcca tttcaactgc cgtaacgatt tctcgtccct aggcttatgg tttcgcctag
    16201 cacaaacact acaggcatca cagcctgtgc tagcatggac tttcctcatg agaagcaatt
    16261 ctcctcacgc gattatccaa aaattgcatg taacaagacc tgaattacaa atcagtattg
    16321 tctaaaattt gtttaccgaa tacttctttt tcaagacgat tcaagcgttt caaaatatca
    16381 aaattcgtca tagaagatga agcagccaca tcaattggat ctgggtgact aggacttgga
    16441 gccgaactca cttgcggttt acgagttaat tcttccttca aatccgcaat ctcctgacga
    16501 agtgacttaa ccaaggtagc ataggtttca tagtccttga tgacatcgtc taaaaactca
    16561 tcaacttcta ccttgctata cccacgaact tcacgtccaa actcttgttc aaaaatatct
    16621 tttgctgaaa aaataatact tgtcatgtct ctctccattc tcgcttgcta gtattattat
    16681 ataaaaaaag gcaaacaaaa atcaaggtca aagcttcaat tttcggaaaa attttcagca
    16741 agttcattta attgatcaaa tgttaatctc tttataaaat agtcctcttg atttttcatc
    16801 ttttggtaaa aataagctag tttcgtttca ttttcttcat cataaaaaag ataggaacta
    16861 gtcgtgtttt ccagcaaaaa ctgctggtaa tctcttaact gccccttgtg ctcatagcga
    16921 ggataagcat atttgacaaa gtctacctgc ttaaaacgac tcagtttcat ctgattgcct
    16981 tcattccaat tttccccatg ggtttcaaaa gcaaaaatgg tggccaactg gaaaccgtac
    17041 tcggttttca tctcctgagc aacctctaaa acccaatatt caaaacccaa acttcctgta
    17101 aacacaagcc aagacacccc atctgctgcc atagcctcta aatctttacg tattgctttt
    17161 tttatcaatt taagacgagg atccttatca gaaaacaaac ccaaatcaaa agcagaatag
    17221 cccaaaacca aagctgtagc catttttaac cctttctgtg caaatttatg gtataataga
    17281 gtgatgttat tgtaccaata aggagaatta tggtcaacta tccacataaa ctttcatcac
    17341 aaaaaagaca accatctctt tctcaaccca aaaatttcgc aaatcgagga atgtcttttg
    17401 aaaagatgat caatgctacc aacgactact atttgtctca gggcttggct gttatacaca
    17461 agaaaccaac tcctattcaa atcgtacgag tggactatcc acaacgaagt cgtgccaaga
    17521 ttgttgaagc ctattttcga caagcttcaa cgacggacta ttctggcgtt tataatggat
    17581 attacatcga ctttgaagcc aaggaaacaa aacaaaaacg tgcgattccg atgaaaaatt
    17641 ttcatccaca tcagattcag catatggaac aagtccttgc ccaacaagga atctgctttg
    17701 tccttcttca cttttcttct cagcaagaaa cctacttatt gccggcattc gatttgattc
    17761 gcttctatca tcaagataag ggacaaaaat caatgccact tggatatatt cgagaatatg
    17821 gatatgaaat caaggctggt gccttccctc aaattcctta tctcaatgtt atcaaagaac
    17881 atttattagg tggtaaaaca agatgaacaa accaacgatt ctgcgcctaa tcaagtatct
    17941 gagcattagc ttcttaagct tggttatcgc agccattgtc ttaggcggag gagttttttt
    18001 ctactacgtt agcaaggctc ctagcctatc cgagagtaaa ctagttgcaa caacttctag
    18061 taaaatctac gacaataaaa atcaactcat tgctgacttg ggttctgaac gccgcgtcaa
    18121 tgcccaagct aatgatattc ccacagattt ggttaaggca atcgtttcta tcgaagacca
    18181 tcgcttcttc gaccacaggg ggattgattc catccgtatc ctgggagctt tcttgcgcaa
    18241 tctgcaaagt aattccctcc aaggtggatc aactctcacc caacagttga ttaagttgac
    18301 ttacttttca acctcgactt ccgaccagac tatttctcgt aaggctcagg aagcttggtt
    18361 agcgattcag ttagaacaaa aagcaaccaa acaggaaatc ttgacctact atataaataa
    18421 ggtctacatg tctaatggca actatggaat gcagacagca gctcaaaact actatggtaa
    18481 agacctcaat aatttaagtt tacctcagtt agccttgctg gctggaatgc ctcaggcacc
    18541 aaaccaatat gacccctatt cacatccaga agcagcccaa gaccgccgaa acttggtctt
    18601 atctgaaatg aaaaatcaag gttacatctc tgctgaacag tatgagaaag cagtcaatac
    18661 accaattact gatggactac aaagtctcaa atcagcaagt aattaccctg cttacatgga
    18721 taattacctc aaggaggtca tcaatcaagt agaacaagaa actggctata accttctaac
    18781 tactgggatg gatgtttaca caaatgtaga ccaagaagct caaaaacatc tgtgggatat
    18841 ctacaactcc gatcaatacg tctcttaccc tgacgatgat ttgcaagtcg catctacggt
    18901 cgtagatgtt tcaaatggta aagtcatcgc ccaacttgga gctcgtcacc aagcaagtaa
    18961 cgtttcattt ggtaccaacc aagctgtgga aaccaatcgt gactggggtt ctgctatgaa
    19021 accaatcacc gattatgcac ctgccataga atacggtgtt tatgattcca ctgcaactat
    19081 ggttaatgat attccttata actatccggg aacaagcaca cctgtctaca actgggatag
    19141 agcatatttc ggtaatatta ctctgcaata tgctcttcaa caatcacgaa atgtcacagc
    19201 cgttgagact ttgaataagg tcggtctaga tagagctaaa accttcctta atggtcttgg
    19261 tatcgactat ccaagcatgc attatgcaaa cgccatttca agtaatacaa cagaatctaa
    19321 taaacaatac ggagcaagta gtgaaaaaat ggctgctgct tatgctgcct ttgcaaatgg
    19381 tggcacttac tataaaccaa tgtatatcca taaagtcgtc ttcagtgatg gaagtaaaaa
    19441 agagttctct aatgtcggaa ctcgtgccat gaaggaaacg acagcctata tgatgaccga
    19501 catgatgaaa acagtcttga cttatggaac tgggcgtgga gcctatcttc cttggcttcc
    19561 tcaagctggt aaaacaggaa cctctaacta tacagatgag gaagttgaaa accacatcaa
    19621 gaacactggc tatgtagctc cagatgaaat gtttgttggt tatactcgta agtattctat
    19681 ggctgtatgg acaggttatt cgaatcgttt aactcctatc gttggagatg gtttcctagt
    19741 tgcagctaaa gtttatcgct caatgataac gtatctatca gaagatactc atccagaaga
    19801 ctggacgatg ccagacggac ttttcagaaa cggggaattt gtattcaaaa atggagctcg
    19861 cccaatatgg actgaaccct ctactcaaca atcctcaaca gctgaaagtt caagctcatc
    19921 atcagatagt tcaacttcac agtctagctc aaccactcca agcacaaata atagtacgac
    19981 taccaatcct aacaataata cgcaacaatc aaatacaacc cctgatcaac aaaatcagaa
    20041 tcctcaacca gcacaaccat aacatttatc atccagattt ttctgggtga ttttttcata
    20101 gcactattgt atttatgtgc ttaacaaaag cctgagaaga catcttctca ggctttttct
    20161 gtactataaa cctcattgga aaagatagag actgcttccg taatcttgtt aagaggtttt
    20221 actaaatact agtctttctt cgtttttact acaaagagag cagatagggc taggctaaca
    20281 cctgctagga agagggctgt gtcagattga ctctcacctg ttgctggcaa gatttgttca
    20341 ggtgtttctg gtctatctat ttcttgctta taatctggcg tcttaccttg ttcggaagct
    20401 aaagagctaa gtttaaactc aggtttctct acagttggag catctgattt cgtagcagaa
    20461 tcttttaatt ggttgagata atctgcaaag tattccacca ttctttccgt caagagatgg
    20521 ttatccgtcg catatttcat gcttgcctga acgctagcta cttcctcttg attgtctttg
    20581 tctgttaatt tctgagcctt agccaaagct gcttcatagc ctgacaagtc aagaggtgtt
    20641 tctgctacct gtggacgagt aaagataagt tccgctgcag attggtattt atcgccacca
    20701 tctccgtaag tcttagtacc tgtaaggaca attttcttag ccttaattgt cttaccaaaa
    20761 tcaatgtctt ttggcttatt gttatctggc caatcagttg cagcaaaggt atgctccttg
    20821 ccagactcat ctgtcacaac aagtttcaca tcacgcaagt taccatttga acctgatcca
    20881 cgtggaatat aacgaagtcc agtgatttca gttgcttctt tcaagaccat ggttgcaggc
    20941 ttgcctacat ctccaccatt ccaagatgta tgccatagac tagacacatt gccatcaaag
    21001 gcattctcaa gaccttcatc tggttgagct ggcgcatcca aactttcaaa gtcatctgct
    21061 accaaagccg ttttcttctg aaccaaagca ttcttcaagg cttcaatctt ggcaatctct
    21121 gcacgcgctt cttccacact gatatcatca tcggcctgac tgaggttaaa gaccgcctct
    21181 ttcaaagcat ccatagactc tttggtgtag ttagtcatgg caaccgttgg caagtagttc
    21241 ttcagagcat tttctgtcaa catcttacct gttagggtaa tttcttcgat ttgaagatta
    21301 tccatcatga agtcgttata accacggaag ttggcatttc caccagaatc accacgagta
    21361 ttacttgcat ttccagttga gtagatacct acccaagtat cccctgtttc tgcacctgtc
    21421 acgaggaagg ttgccttctt ggctttctta gaatctgtcc aagtatttgg caattcatgc
    21481 atttccaagt tgcttgcttg agtgccacga cgacctgact ggaattctcc cttaccgact
    21541 acaaaagcat aggtattgtc tgaacctgct tcgtattcaa aggttacacg gtaggtctta
    21601 cctgcttcaa aacggaagtt ttgcggaatg gtttggtaaa ccaagttacg acggctcact
    21661 agtccatttg tcttgagtga ccaatttcct tcgataacat catcgacttt cttaccgttc
    21721 caaccacgtt gtgtatatgg atcgtgtttt tcagacaagt gagtgcggtt gtcttcgaca
    21781 ccttcgacac cacccactac aaatgggaag ataccctgag caacattttc aaagtcttgc
    21841 ttgaaggtgc ctttacctgt atcatgcttg tctccgtaca tgcttgaatt gttttcaaag
    21901 gtacgaattt catcaaagta agttgcttca tcaccagctt cacgactcaa tgtcagagta
    21961 acatttgaga cgtccgatcc agttgtaaag aaggcgtaca tgttttggaa gtaacttgta
    22021 tcgtcaactg tagcattgtt acgacgtgta ttgtgggcgt aggcttttac atagttgagg
    22081 gcgagagact tattggtata agtagtcact tctttttcac cagtattcac agtgatactt
    22141 gccttggcat tactacggtt atcgacaccg acataaacgg catacttggt atttggtttc
    22201 aagccagtta atttctgagt gagactaact ttttctttgt ttccttgaat acgaagcata
    22261 tcgtttgccc cttgagactt gacaatttct gccttagaag catcgcctga aatggtccag
    22321 tgtttcaagg ttccactatt aaatccttgg tcatagatgt gcatgccttc actccatgac
    22381 atttcaggat tggtttgttt tgaacggtaa agtacgtatg gttgatttgc tagaagatct
    22441 agggtaattt taccatcttt tacagttagt tcttgctctt ctgtcttacc ttggtcagtt
    22501 agcttgtaaa ggtaaacctt gctctttgcc caatcgcttg gaagggtcca agttgttgca
    22561 ccagcctgcg tattgaagta gtacattttt tccttatcag tagaaagttt cttaccattt
    22621 gcatcccagt tccaaggagt caagtaagct gaaccatctt ggatgacacg tccgttgagc
    22681 gttactgtac gttcgcgata ttgtgggcta ttgacatcat ttgacttacg agttacaact
    22741 actttattat tgtcagcatc taccaattcc actcgcattt ctggagtcca tttataggtg
    22801 ctaccgttat cggtcatagt caccggtgta ccattttccc atttgcttac agtgaagtgt
    22861 tggaaatact tggtcatgac gtcatgggca aataagttgg ttacatagcc attgtagtca
    22921 cttcttcctt gccagccttc aaagtctttc atgctgtagc cacctagcag tggatagttg
    22981 gctgcaccac cataacttct gtagtcccca acccaagcat ctttttggtg gttacggata
    23041 aagcgggtga tggcactgtt gataccttta ttggtgtagc caccgtaggt caagtcagct
    23101 gcccagtgat ggaaggtaga gtcgtactca ccaccatggc cccactcgat cgcaaagcgc
    23161 cagccttgtt tgttaatttc tttagcaaga acgtgggtag cccaggcacc gttatcacct
    23221 gattgaccat taccccaaac gtccacatag ataaagtcga gaccgtcacc aagttttttc
    23281 ttcaaatctt cccaacgtgc caaacgacca tgagctaggt cataggcagc atcaatgttg
    23341 ataccttgat ctagccagtt ccaaccatag ctatagcttc catctggatt cttacggaga
    23401 attttttcat tgaaatattt agactcagga taagtttctg aagcgttaac gtggatacct
    23461 agatgagctc catatttctt agccttctca attagggtct tgaagtcttc gacaccaccg
    23521 atacgcttac caatatcagc atagttcaag tgaccagagt catgaccttc actaccatat
    23581 cctttaagga gaacaccttg cccaagacca tctgtgtgga gattgatttt cttgatacca
    23641 tccaaggtca taaggaatgg gttttgtgct tgagaaccaa agttcatcgc gatacggtaa
    23701 gctgtgatat ccttaacttt ttcccaacct tgagggttgt tcataatgct acgataagca
    23761 atggcaccat cttgccaatc aacgttcttg tctgcattgg catcttcagt gataacaacc
    23821 ttagcactcg gaagttcctt cgtgtattct gggaaaacaa tgcccttata agctttttcc
    23881 cattgccatt cagagctgtg gattcctaca tagttggcat ttccgactgt ttctttataa
    23941 gctgtcaaac gagtccagtc attcgaacca ccaccatagc tgttttgaga gttactccaa
    24001 acaccagcag caagcttatc tgtagaaaca aatccataca tgtaaccctt ggctaggtct
    24061 ttcattggat tggttacatc gatatgatca tctccgctga catgcgtatt gtttgacatg
    24121 gttgccccat caaacttagc accagtttga tcactagaaa cagagactaa agcattgccg
    24181 aggaaactaa tagaagaaag tagttttctt tcgtcatcaa tcttttgacc tggagtgact
    24241 tgattgtggt tgacaatctt ggtcacatca aagtgcaatt gattgtccac aacttgcaag
    24301 cgtactgtca tttccgcatt gattaagtga gcatcatcgc gaagcttcat caagtactct
    24361 gctgttgtct cattgatttt cttataagtg acttcagggg tgattcggtg gttattgata
    24421 aagacttggt tgaactgttg cacctgtcct ggcaaagtat gtccattcaa gctgtattcc
    24481 ttgacacgag ggaaggcttg gtcaatcact gctttgagga ccttagactg aatcgtgtca
    24541 taagtcacct tgctatcatc aacttcagga cctgtttctt tttcagcagg ggtatcctct
    24601 gtttttaccc cctcttggtt atccgtttta acgctaacaa ctgttcgctc atcgtcataa
    24661 gagcccgcct tgagaagaat cttcttctca tttttaagat ggtcattgac cgcagctggt
    24721 agagtcactg tgtcaaagag attgacatcg ttattgctgg catttagctg accgtctgac
    24781 ttgagagtga tagagagacg gtttgttgat cctgtttcag gagcagcaac acgactacct
    24841 ctataccaag tgctagttgt tggagattta tactcccaga accagccatc cttgtcataa
    24901 ccgacaaaaa cattattatt ggtatcttta aatttcaaga agacaccaaa gcgtgatttg
    24961 cccttttcag aatcttcttt gaaggttaaa tcaacagttg catttccatt ggcatcaacg
    25021 gtcaagccct tcttttcaaa cagggctggt ttgcctgcgt tatcattttg agcagttgag
    25081 gatagttggt tgtagcggac acctttttct tctcggatag tgactgttcc ctgttgttct
    25141 tttttctcta ccgtttgcca ttcaggggtt accgtcttaa gtgtttcagg tttagcagct
    25201 gcatgtttat cctcttttgg tttttcttca gccggttttt ctttttcaag tgctaatagt
    25261 tcttcttctg tcttaggtcc atctgtgact tctggagaac cttggtcttc tcccacctta
    25321 ggcgcttcaa aatcacgccc atcattctct tttgctgttg caagagcagt agctaaatca
    25381 gctggtaagt tcgccgtgga accagactgc acgctatctg caagaaccgg acttgtccca
    25441 aagaatgcag ctccaatcat aacagaagca acacctaatg aaaatttccg aatactatat
    25501 ttacaacgtt tttcaaataa tcctttattc ataaacttct aaatcctttc atttttgagc
    25561 aagcgtttac attttctttt taaaaaatac tccttcctct gaaagtgcaa tgcttaaccc
    25621 taataaataa aaaataatta tacttttaat ataacaaata ataactgaga aagcaatagg
    25681 aaacaagtaa aattaacaaa aattttctct attctgacaa aaagaggctc taacttttgg
    25741 gggtcagtac atttagaatc tttctttaca aatgtaaaaa aggattcagc attcaagaga
    25801 aatactaaat cctttcttat attttgcaac agttatttca catgttttgc gagatcttct
    25861 tgagtctttt tattagactc ttctttttct ttcatccatt tttcctgagc tttttggtat
    25921 tcatctacag tgactgcctt gtcttgaagt tccaagtatt tatataagat tggttcactt
    25981 gtacctttat ttcctgacaa tgcaaatggt attgtaaatg gtaccatctt agacaagatt
    26041 gggcgccctg tacgagatgt agttggaata atcaaagcac tatctgtcaa ccaagcttgg
    26101 gctgcagcgt atttatcata gcgtttagca acatctgtag cctcatcacc agcctcagtg
    26161 accaattttt cgtagtcata tagacctact tttttagcag ctacattatc ttcccctgag
    26221 tcaaacccta aatatgtttt agtactttct cctacagatg gtttgatgat atcaaggtag
    26281 gttgatggat cggcaaagtc tggaccccaa ccgacattat ctgataaatc ccagtcttcg
    26341 ccagcagcat tttcagcaaa atatgtaata ttgtttactt cgtctttttg tagttgttga
    26401 atatcaatga ctacattatc cgctcctaaa gttgcttcca aggattgttt catagattgg
    26461 acgcgctgaa cttttgtagt tgctgtttgg tcaactggca tatccaaatg aattgggaat
    26521 gtcacacctt ctgcttgtaa ggctgattta gctttagcaa attcagcctt ggctttttct
    26581 ggattgtaaa gaccatcctg agaatctgca agattaacat ccttccattc atccccataa
    26641 gtaaccaatt tctctttgac catatcgcca aagtttttac catctgcttg aacaaatgtt
    26701 ggtggaacaa agatattacg taagattttg cttgctccag tttgtccatt caactgagag
    26761 gcataggctg tacgatcaaa accaaaggca atagcctgac ggaaatcctt gtttaagaga
    26821 gcctttttag tcgatgcctt ttgttcgtcg ctggtcttag atgtgtattt ataggactga
    26881 cggtcaatat ttgtaccaac tagatacgta atagagtctt gttgagtata gacaatattg
    26941 tccttcatac tcttctcaag ctctgcgaaa cttgcacttg ttggatagag acgagctgct
    27001 gtaaggctac catctttaaa gttttctgca ggtttgctgg tatcttgacc atcccagaat
    27061 gacaatttaa ctttgtcaat atgcacattg tccttatccc agtagttcgg atttttcgca
    27121 aattcaacag aagatttggt cacaatggat ttcaacaaat aaggtccatt atacaagaga
    27181 ctgcttggat ccgtagcttt ggcaaaatca tccccttttg agttcaaaaa ctcttcatta
    27241 actggcgcaa gcacacccat ggttgtctta gaattccaga agctttctgg tttgttcaaa
    27301 gtgtactgaa ctgtctgttc atccagagcc ttaattccta cttgtgagaa atctttgatt
    27361 tcccctttta cataggcatc caaccctttg attgattctt gaacaaggta aagagcatct
    27421 gattttttat cagcagcata ttttagtcct gttacaaagt cttgagcttt gactgccgcg
    27481 tattcttccc cttcagaagt ataccatttt gcatccttac ggataatata agtgtaagtc
    27541 aatccatcct tggatacaga ccaatcctca gccatagacg gcacaaagtt cccgtagcga
    27601 tcattttcta gcaaaccatc aaccacgtta ctggtaatat ttgctgtcgc agccttagca
    27661 gttgtcaaat agttgaggtt atcagggtct gtctcataaa tatatgagaa tgtcttctca
    27721 cctttagcgc ttgaacctga tccagagcat gcagctaaag tagtcgccgc caataatgtc
    27781 acgcccgcaa gggcaaatag ttttgaactt ttcatcattt tctcctttaa aactttctct
    27841 ccattataga ctcttttcag aaagttgtca acagaatttt cagaattttt gaaaattatt
    27901 tttcaaacaa catctttgca aaaaatatga atatcattgt aagcgcccaa taacgaagta
    27961 tattgaaaaa tctccagatt agtgaactca cggatagttc ctaatctgga gatttcttat
    28021 ttgcactttt cttgtacaac tttagtccat ggtaaataag cctctaaaac ctctttgttt
    28081 acgagagttt cctcgtttgg aagacattct agaagatagg atagatattt ctcgctattt
    28141 ataatggatt gaaataagat atgaacaaat cgattaggaa aggaaaattg atttatagaa
    28201 atgttttagc agtcgatgcg tactgttata gattcaacgc actataattg atgacgttta
    28261 gctgtttcca acaagctcat aataatagct cttgctttag ctccttcaaa actttgagaa
    28321 aataaccacc ctcgcttttt taaactgagc tcaggctaaa agagtccact ggactctttt
    28381 actccgtccc ataaccaatg atttaatggc gcgttcagct agattattgg aaaggaccag
    28441 atgtccgtct ttcaaaatag tcttaaaggt ttctttatac ttgaggctgt attcaattgc
    28501 ccttcctagt tttgaacccg ataaaactga ctgacgccgg caccaagcaa agaagtcttc
    28561 cattaggggt tggagctctt cttgacgttt ctgtagtcgt tcatcagctg gcaaagcctc
    28621 ccagtctctt tccaaggaaa ataactgatt acaataagct aaacctttag ctcctaagga
    28681 tgatttatct gcttgcttgg gggtcgcttc aaaaaacttc cttctcacat gcgcccaaca
    28741 tccaacaagt tcagcttctt ccagttgacg ataagcttct agcggttcgc agtttaccaa
    28801 gcttagcgtc gccttgctcc taaaccttgg actgctatcg cataggcaga actagaggac
    28861 taaagtccta agttactgcc gcaacatatc acaatgcaca tagccagaat aatctcctag
    28921 gaattcttgt actactaaac cactccgacg ctgatcatga tggtacagcg tgattgcttg
    28981 attctcagct ttcccagaca aaaaggtcca atagtaggtc agatggctat cactctctag
    29041 aacccgataa gaggtttcat ccgcatgaag aagaggttgt tctaacaact tttctcgtaa
    29101 aaggttataa agggactcta aatagtattg acttgccttg atatgccaat tagagatttc
    29161 cttacgtgtg attggtaaac ccatcctagc ccaatcttct tct
//
LOCUS       DAVHTH010000025        28006 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.025, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000025 DAVHTH010000000
VERSION     DAVHTH010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 28006)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28006)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28006
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.025"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            522..1700
                     /locus_tag="VVR63_001118"
     CDS             522..1700
                     /locus_tag="VVR63_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEU6129142.1"
                     /translation="MSNSFVKLLVSQLFANLADIFFRVTIIANIYIISKSVIATSLVP
                     ILIGISSFVASLLVPLVTKRLALNRVLSLSQFGKTILLAILVGMFTVMQSVAPLVTYL
                     FVVAISILDGFAAPVSYAIVPRYATDLGKANSALSMTGEAVQLIGWGLGGLLFATIGL
                     LPTTFIILVLYIISSFLMLFLPNAEVEVLESETNLEILLKGWKLVARNPRLRLFVSAN
                     LLEIFSNTIWVSSIILVFVTELLNKTESYWGYSNTAYSIGIIISGLIAFRLSEKFLAA
                     KWESILFPLVAMAIVTLTILYFPNAQMFLLFSALVGMLSQLKEVPESVFLQETVEENH
                     LVNVYSVLEVISTLAFSVFVLLMSYITESFGISISFWLSAICLMIEAILIYIRRDYFK
                     "
     gene            2014..2145
                     /locus_tag="VVR63_001119"
     CDS             2014..2145
                     /locus_tag="VVR63_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HEU6129143.1"
                     /translation="MKQRKELYLFLGRTALYFLIFLGLLYFFSYLGQGQGSFIYNEF"
     gene            2166..3716
                     /gene="dltA"
                     /locus_tag="VVR63_001120"
     CDS             2166..3716
                     /gene="dltA"
                     /locus_tag="VVR63_001120"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HEU6129144.1"
                     /translation="MSNKPIADMIETIEHFAQTQPSYPVYNVLGQEHTYGDLKADSDS
                     LAAVIDQLGLPEKSPVVVFGGQEYEMLATFVALTKSGHAYIPIDSHSALERVSAILEV
                     AEPSLIIAISAFPLEQVSTPMINLAQVQEAFAQGNNYEITHPVKGDDNYYIIFTSGTT
                     GKPKGVQISHDNLLSFTNWMITDKEFATPSRPQMLAQPPYSFDLSVMYWAPTLALGGT
                     LFTLPSVITQDFKQLFAAIFSLPIAIWTSTPSFADMAMLSEYFNSEKMPGITHFYFDG
                     EELTVKTAQKLRERFPNARIINAYGPTEATVALSAVAVTDEMLATLKRLPIGYTKADS
                     PTFIIDEEGNKLPNGEQGEIIVSGPAVSKGYMKNPEKTAEAFFEFEGLPAYHTGDVGT
                     MTDEGLLLYGGRMDFQIKFNGYRIELEDVSQNLNKSRFIESAVAVPRYNKDHKVQNLL
                     AYVILKDGVREQFERDIDITKAIKEDLTDIMMSYMMPSKFLYRDSLPLTPNGKIDIKG
                     LINEVNKR"
     gene            3713..4957
                     /gene="dltB"
                     /locus_tag="VVR63_001121"
     CDS             3713..4957
                     /gene="dltB"
                     /locus_tag="VVR63_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HEU6129145.1"
                     /translation="MMEFFQQLPHLEPYGNPQYFVYVIAATLPIFIGLFFKKRFAWYE
                     VLVSLFFIVTMLVGGKTNQLAALGIYLCWEILLLLFYKHYRKSKDGKWVFYLVSFLSL
                     LPIIFVKVQPAINGTQSLLGFLGISYLTFRSVGIIIELRDGVIKDFTLWEFLRFLLFM
                     PTFSSGPIDRFKRFNENYQAIPERDELMDMLDESVRYIMRGFLYKFILAHVLGETLLP
                     PLKNLALQSGGFFNLYALAVMYTFGLELFFDFAGYSMFALAISNLMGIRSPINFNKPF
                     LSRDLKEFWNRWHMSLSFWFRDFVFMRMVMVLTRKKVFKNRNVTSSMAYIVNMLIMGF
                     WHGVTWYYIAYGLFHGLGLVINDAWVRKKKTLNKERKKAGKAALPENRWIQLLGMVVT
                     FHVVMLSFLIFSGFLNNLWFKK"
     gene            4971..5210
                     /gene="dltC"
                     /locus_tag="VVR63_001122"
     CDS             4971..5210
                     /gene="dltC"
                     /locus_tag="VVR63_001122"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005591431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HEU6129146.1"
                     /translation="MDIKSEVIEIIDELFMEDVSDMMDEDLFDAGVLDSMGTVELIVE
                     IENRFDIRVPVTEFGRDDWNTANKIIAGIVELQNA"
     gene            5203..6471
                     /gene="dltD"
                     /locus_tag="VVR63_001123"
     CDS             5203..6471
                     /gene="dltD"
                     /locus_tag="VVR63_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HEU6129147.1"
                     /translation="MLKRLWMIFGPVLIAGLLVFLLIFFYPTEMHHNLGAEKRSAVAT
                     TIDSFKERSQKVRALSDPNVHFVPFFGSSEWLRFDGAHPAVLAEKYNRSYRPYLLGQG
                     GAASLNQYFGMQQMLPQLENKQVVYVISPQWFSKNGYDPAAFQQYFNGDQLTSFLKHQ
                     SGDQASQYAATRLLQQFPNVAMKDLVQKLASKGELSTADNEMIELLARFNERQASFFG
                     QFSVRGYVNYDKHVAKYLKILPDQFSYQAIEDVVKADAEKNTSNNEMGMENYFYNEQI
                     KKDLKKLKDSQKSFTYLKSPEYNDLQLVLTQFSKSKVNPIFIIPPVNKKWMDYAGLRE
                     DMYQQTVQKIRYQLESQGFTNIADFSKDGGEPFFMKDTIHLGWLGWLAFDKAVDPFLS
                     NPTPAPTYHLNERFFSKDWATYDGDVKEFQ"
     gene            6626..7066
                     /gene="adcR"
                     /locus_tag="VVR63_001124"
     CDS             6626..7066
                     /gene="adcR"
                     /locus_tag="VVR63_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent transcriptional regulator AdcR"
                     /protein_id="HEU6129148.1"
                     /translation="MRQLAKDIDAFLNEVILQAENQHEILIGHCTSEVALTNTQEHIL
                     MLLSEESLTNSELARRLNVSQAAVTKAIKSLVKEGMLETSKDSKDARVIFYQLTDLAR
                     PIAEEHHHHHEHTLLTYEQVATQFTPNEQKVIQRFLTALVGEIK"
     gene            7066..7770
                     /locus_tag="VVR63_001125"
     CDS             7066..7770
                     /locus_tag="VVR63_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEU6129149.1"
                     /translation="MRYITVEDLSFYYDKEPVLEHINYSVDSGEFVTLTGENGAAKTT
                     LIKASLGILQPRIGKVAISKTNTQGKKLRIAYLPQQIASFNAGFPSTVYEFVKSGRYP
                     RKGWFRRLNAHDEEHIKASLDSVGMWEHRDKRLGSLSGGQKQRAVIARMFASDPDVFI
                     LDEPTTGMDAGSKNEFYELMHHSAHHHGKAVLMITHDPEEVKDYADRNIHLVRNQDSP
                     WRCFNVHENGQEVGHA"
     gene            7763..8569
                     /locus_tag="VVR63_001126"
     CDS             7763..8569
                     /locus_tag="VVR63_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEU6129150.1"
                     /translation="MLSLLSYDFIQRAFLAVIAMSLFSPVLGTFLILRRQSLMSDTLS
                     HVSLSGVAFGLVLGISPTVSTIAIVLIAAVFLEYLRTVYKSFMEIGTAILMSTGLAVS
                     LIVMSKGKSSSSMSLDQYLFGSIVTISEEQVISLFVIAAVVLILTFLFLRPMYILTFD
                     EDTAFVDGLPVRTMSILFNMVTGVAIALMIPAAGALLVSTIMVLPASIALRLGKNFKS
                     VMLLASAIGFLGMVAGLYISYYAETPASASITIIFVTVFILISLVRRFIK"
     gene            8579..10084
                     /gene="adcA"
                     /locus_tag="VVR63_001127"
     CDS             8579..10084
                     /gene="adcA"
                     /locus_tag="VVR63_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding
                     lipoprotein AdcA"
                     /protein_id="HEU6129151.1"
                     /translation="MKKISLLLASLCALFLVACSNQKQADGKLNIVTTFYPVYEFTKQ
                     VAGDTANVELLIGAGTEPHEYEPSAKAVAKIQDADTFVYENENMETWVPKLLDTLDKK
                     KVKTIKATGDMLLLPGGEEEEGDHDHGEEGHHHEFDPHVWLSPVRAIKLVEHIRDSLS
                     ADYPDKKETFEKNAAAYIEKLQALDKAYAEGLSQAKQKSFVTQHAAFNYLALDYGLKQ
                     VAISGLSPDVEPSAARLAELTEYVKKNKIAYIYFEENASQALANTLSKEAGVKTDVLN
                     PLESLTEEDTKAGENYISIMEKNLKALKQTTDQEGPAIEPEKAEDTKTVQNGYFEDAA
                     VKDRTLSDYAGNWQSVYPFLEDGTFDQVFDYKAKLTGKMTQAEYKAYYTKGYQTDVTK
                     INITDNTMEFVQGGQSKKYTYKYVGKKILTYKKGNRGVRFLFEATDADAGQFKYVQFS
                     DHNVAPVKAEHFHIFFGGTSQEALFEEMDNWPTYYPDNLSGQEIAQEMLAH"
     gene            complement(11213..11986)
                     /locus_tag="VVR63_001128"
     CDS             complement(11213..11986)
                     /locus_tag="VVR63_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEU6129152.1"
                     /translation="MIKDERVLELIEIIKKKKRIAVKELAEITFSSTSTLRRDLIFLE
                     NQGLIKRKHGYVTLSSMNTIELSHQIREGESTRQKRLIASLAKDFIRSGMCIYLDSST
                     TVYELCPYLSELDNLIIFTNGLHTAQTLSETVKDSSKIFITSGEVKHQSCSVVNYDKE
                     NSLLDHFNIDLAFCSARGIDDQYVYEASLSQAISKKNIIDKAHETILLIDSSKFYKTG
                     FFKINPLSKYTTFISDTLPNQKLLDAVELFDGEWVSDIQ"
     gene            12162..13565
                     /locus_tag="VVR63_001129"
     CDS             12162..13565
                     /locus_tag="VVR63_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HEU6129153.1"
                     /translation="MEAVLAIDLGATSGRAIVGYLSENKLVMEEINRFSNLPIRVKGH
                     LSWDIDFLLAKILESIRLANTSYKILSIGIDTWGVDFGLIDNEGKLLLQPVHYRDERT
                     KGVLKEISEMTELEKLYSETGNQIMEINTLFQLFKARQESPDSFYKTNKILLMPDLFN
                     YLLTGKFSTEKSIASTTQLFDPRSQNWNQNILKLFELDSSLLPEIVSEGNVLGRIKKE
                     YGLGDIPVVNVCSHDTASAIVSVPKTEGSLFISSGTWSLVGVELTSPILTTESFSYGF
                     TNEVGKDGEITFLKNCTGLWIIEELRRSFERRGKAYSFDDIRTMVEKEKENLPLIDTE
                     STEFATESDMHKTLTEYLAYHHETREWTDGQLFKIVYESLAETYRKAIELLEELTHKV
                     YKRIYVIGGGARASYFNQMIADRTGKEVLTGSTEGTAVGNIVVQLIAMGQLKGMEEAH
                     HVIEEFLQLESYYSQKN"
     gene            13680..14318
                     /locus_tag="VVR63_001130"
     CDS             13680..14318
                     /locus_tag="VVR63_001130"
                     /EC_number="4.1.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001286141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fuculose-phosphate aldolase"
                     /protein_id="HEU6129154.1"
                     /translation="MSDVKQELIKYGKKLVETDLTKGTGGNLSVFDREKQLMAITPSG
                     IDFFEIKESDIVVMDINGNVVEGERLPSSEWYMHLIQYQTRDDIDAIIHAHTTYATVL
                     ACLREPLPASHYMIAVAGKDVRVAEYATYGTKELAVNAAKAMEGRRAVLLANHGILAG
                     AQNLLNAFNIVEEVEYCAKIYCLAKNFGEPVVLPDEEMDLMAEKFKTYGQRK"
     gene            14330..14770
                     /locus_tag="VVR63_001131"
     CDS             14330..14770
                     /locus_tag="VVR63_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RbsD/FucU family protein"
                     /protein_id="HEU6129155.1"
                     /translation="MLKHIPKNISPDLLKTLMEMGHGDEIVLADANYPSASCANKLIR
                     CDGVNIPELLDSILYLMPLDSYVDSSIQFMNVVSGDDIPKIWGTYRQMIEGHGTDLKT
                     ITYLRREDFYERSKKAYAIVATGETSLYANIILKKGVVVERENV"
     gene            14763..15194
                     /locus_tag="VVR63_001132"
     CDS             14763..15194
                     /locus_tag="VVR63_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000483177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU6129156.1"
                     /translation="MFNRGILVASHGNFASGALMTAEMFVGETTNDRVRTLGLMPGEN
                     IVEFEHYFKNQVNELLDSNQEVIVLTDLIGGSPNNVALSRFLNLDSVDIVTGFNIPLL
                     VELISSYDSKINLEEIVQNAQNSLFNVKQQLNVEEEEDLCL"
     gene            15185..15655
                     /locus_tag="VVR63_001133"
     CDS             15185..15655
                     /locus_tag="VVR63_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000020992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU6129157.1"
                     /translation="MSIEFVRIDDRLVHGQVVTTWLKKYDIEQVIIVNDRISEDKTRQ
                     SILKISAPVGLKIVFFSVKRFVEVLNSVPIKKRTMLIYTNPKDVYDSIEGNLKLEYLN
                     VGQMSKTEENEKVTGGVALGEEDKYYFKKIVDKGTRVEIQMVPNDKVTMLEKFL"
     gene            15680..16453
                     /locus_tag="VVR63_001134"
     CDS             15680..16453
                     /locus_tag="VVR63_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000899624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEU6129158.1"
                     /translation="MLFTQALLVTLVGIIATIDYNGPLFMIHRPLVTSAMVGLVLGDF
                     TQGVLIGSALELTWLGVTGIGGYTPPDTISGAIIGTAFGILSGQGETAGIAIAVPIAV
                     ATQQLDVLAKTLDVYFVKKADNDAKNGDYSKIGFYHYSSLVLITLFKIVPIFLAIMLG
                     GEYVADLFAKVPPIVMQGLNSAGALLPSIGFGMLLNMMLKKNMWVFLLIGFICSVYGG
                     MSTIGISLVGIAVAYFYDMIGSKPQETTSSSDVEEDLDL"
     gene            16450..17250
                     /locus_tag="VVR63_001135"
     CDS             16450..17250
                     /locus_tag="VVR63_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEU6129159.1"
                     /translation="MMNNKVTKVELKKVFKRSFMYGSSWNYERMQNLGFLYTILPVLK
                     KLYPDKDSASPAMKRHLEFFNTHQTAAPFILGVTSAMEEQEGNEGAASITGIKVGLMG
                     PLAGLGDSLFWLTLVPICFSIGASYSKDGGALGIFIALILFNIINIPVKYFGLKYGYT
                     KGSSLIQENNTKGTLNRVTSMATALGLVLVGGLIPSMVGINFGLEFKQGELVISVQEM
                     ITKLIPGFIPMALTLLMCKLIRKGKNPVVLIFSVMAIGVILVVLGILK"
     gene            17309..19603
                     /locus_tag="VVR63_001136"
     CDS             17309..19603
                     /locus_tag="VVR63_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HEU6129160.1"
                     /translation="MKLWYKKAAANWNEALPIGNGHLGGMIYGSATKECIQLNDETIW
                     YRGKSDRNNPDSLLHLKKIREYLLDGEIQKAEELIKLTMFATPRDQSHYELLGELCIE
                     HIDIQSCALSLYERELDLDTAISNVVFEPNSCNLQIKREYFTSFNKNILCCRIVSSVQ
                     NTLNLNINLGRNKRFNDEVSKLDSSTILMSASAGGRKGVQFKVVCHSKVTDGEVSVLG
                     ETIVIRNATEVFLYLKSMTDYWGNIDISSLQGEFSSIDYFTEKDEHVKKYQEQFNRVD
                     FKLDYSKGCLSIPTNLLLENTKKYSNYLTNLLFHYGRYLLISSSQPNGLPANLQGIWC
                     DELNPIWGSKYTININTQMNYWMVGPCDLPEVEYPLFDMLERMREPGRLTAKKMYGAR
                     GFTAHHNTDGFGDTAPQSHAMGAAIWVLTIPWLCTHIWEHYLYFQDERILTEHFEMIK
                     EAFLFFEDYLFEVDGYLMTGPSVSPENKYRLKNGIEGNACLSSTIDNQILRYFCDSCI
                     GIAKQLGDNSDFISRVKELKKKLPRTKIGSNGQIQEWLEDYEEVEPGHRHISPLFGLY
                     PYNEIDIHKTPELAEAAKITINRRLSNANFLSSQDREQAINNWLVSGLHASTQTGWSA
                     AWLIHFFARLYQGEPAYNQINGLLNNATLGNLFLDHPPFQIDGNLGLVSGICELLVQS
                     HHNWLSLIPALPSAWSEGEVKGFRVRGGYKVSFAWKNGDITFLKLEGGNKDQKVRVRI
                     YGKNTDVQNIELVFNSEKIIELNF"
     gene            19613..22729
                     /locus_tag="VVR63_001137"
     CDS             19613..22729
                     /locus_tag="VVR63_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HEU6129161.1"
                     /translation="MNKEKIKRKLITILFVCIGMLCFGLLAGVKADNRVQMRTTINNE
                     SPLLLSPLYGNDNGNGLWWGNTLKGAWEAIPEDVKPYAAIELHPAKVCKPTSCIPRDT
                     KELREWYVKMLEEAQSLNIPVFLVIMSAGERNTVPPEWLDEQFQKYSVLKGVLNIENY
                     WIYNNQLAPHSAKYLEVCAKYGAHFIWHDHEKWFWETIMNDPTFFEASQKYHKNLVLA
                     TKNTPIRDDAGTDSIVSGFWLSGLCDNWGSSTDTWKWWEKHYTNTFETGRARDMRSYA
                     SEPESMIAMEMMNVYTGGGTVYNFECAAYTFMTNDVPTPAFTKGIIPFFRHAIQNPAP
                     SKEEVVNRTKAVFWNGEGRISSLNGFYQGLYSNDETMPLYNNGRYHILPVIHEKIDKE
                     KISSIFPNAKILTKNSEELSSKVNYLNSLYPKLYEGDGYAQRVGNSWYIYNSNANINK
                     NQQVMLPMYTNNTKSLSLDLTPHTYAVVKENPNNLHILLNNYRTDKTAMWALSGNFDA
                     SKSWKKEELELANWISKNYSINPVDNDFRTTTLTLKGHTGHKPQINISGDKNHYTYTE
                     NWDENTHVYTITVNHNGMVEMSINTEGTGPVPFPTPDKFNDGNLNIAYAKPTTQSSVD
                     YNGDPNRAVDGNRNGNFNSGSVTHTRADNPSWWEVDLKKMDKVGLVKIYNRTDAETQR
                     LSNFDVILYDNNRNEVAKKHVNNLSGESVSLDFKEKGARYIKVKLLTSGVPLSLAEVE
                     VFRESDGKQSEEDIDKITEDKVVSTNKVATQSSTNYEGVAALAVDGNKDGDYGHHSVT
                     HTKADSNAWWQVDLGEEFTVSKVDIYNRTDAEPQRLSNFDVIFLSSSGEEVFRRHFDK
                     VVDGLLSLKVPSVGAKLVKIELKSAAIPLSLAEVEVYGSKRTPKKLSNIALTKETRQS
                     STDYNGFSRLAVDGNKNGDYGHHSVTHTKGDSPSWWEIDLAQTEELEKLIIYNRTDAE
                     IQRLSNFDIIIYDSNNHEVFKQHIDSLESNNLSIDLKGLKGKKVRISLRNAGIPLSLA
                     EVEVYTYK"
     gene            22786..24552
                     /locus_tag="VVR63_001138"
     CDS             22786..24552
                     /locus_tag="VVR63_001138"
                     /EC_number="5.3.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose isomerase"
                     /protein_id="HEU6129162.1"
                     /translation="MIQHPRIGIRPTIDGRRQGVRESLEVQTMNMAKSVADLISSTLK
                     YPDGEPVECVISPSTIGRVPEAAASHELFKKSNVCATITVTPCWCYGSETMDMSPDIP
                     HAIWGFNGTERPGAVYLAAVLASHAQKGIPAFGIYGRDVQEANDTDIPEDVKEKLLRY
                     ARAALATGLMRDTAYLSMGSVSMGIGGSIVNPDFFQEYLGMRNESVDMTEFTRRMDRG
                     IYDPEEFERAMVWVKEHIKEGVDRNREDLILSKEEKEKQWEFVIKMFMIGRDLMVGNP
                     RLAELGFEEEAVGHHALVAGFQGQRQWTDHFPNGDFMETFLNTQFDWNGIRKPFVFAT
                     ENDSLNGVSMLFNYLLTNTPQIFADVRTYWSPEAVERVTGYTLEGRAAAGFLHLINSG
                     SCTLDGTGQATRDGKPVMKPFWELDESEVQAMLENTDFPPANREYFRGGGFSTRFLTK
                     GDMPVTMVRLNLLKGVGPVLQIAEGYTLELPEDVHHTLDNRTDPGWPTTWFAPRLTGK
                     GAFKSVYDVMNNWGANHGAITYGHIGADLITLASMLRIPVNMHNVPEEDIFRPKNWSL
                     FGTEDLESADYRACQLLGPLHK"
     gene            24698..25849
                     /locus_tag="VVR63_001139"
     CDS             24698..25849
                     /locus_tag="VVR63_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HEU6129163.1"
                     /translation="MATFYVPAVNLIGKGVVNEVGPYIKELGYKKALLVTDKYIEGSD
                     ILPKTLKPLDTEGIEYVIFSDVEPNPTCKNVTDGVAALQEHGCDFIISLGGGSPQDAA
                     SCISIMATNGGRPQDYEGLHKSAKKGLPVVAINTTAGTSAEITINYVITDEERKVKMV
                     MVDKNSLALISVNDPELMLSKPKGLTAATGMDALTHAVEALVTPGAYDVTKKLSIGAI
                     ELIKEYLPRAVENGHDIEAREGMVNAIFLGGMSFNNAGLGYVHSMAHQLGAVYNLPHG
                     VCCAMLLPVIERENAKRVPEAFRNVAKALGLHVEGKSDQECADYAIAEIEKLSETVGI
                     PKKLTELGIEEKDFDFEYLSKNALIDACAPGNPFMPTLEETIAFYKELF"
     gene            25994..26878
                     /locus_tag="VVR63_001140"
     CDS             25994..26878
                     /locus_tag="VVR63_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEU6129164.1"
                     /translation="MIFLIVCVLLLVIVTLSTVYVVRQQSVAIIERFGKYQKVANSGI
                     HIRLPFGIDSIAARIQLRLLQSDIVVETKTKDNVFVMMNVATQYRVNEQSVTDAYYKL
                     IRPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMTTYGYIIVKTLI
                     TKVEPDAEVKQSMNEINAAQRKRVAAQELAEADKIKIVTAAEAEAEKDRLHGVGIAQQ
                     RKAIVDGLAESITELKEANVGMTEEQIMSILLTNQYLDTLNTFASKGNQTIFLPNTPN
                     GVDDIRTQILSALRAEKK"
     gene            27276..27527
                     /locus_tag="VVR63_001141"
     CDS             27276..27527
                     /locus_tag="VVR63_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657761.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEU6129165.1"
                     /translation="MKEFQFERKQRFSLRKYAIGACSVLLGTSLFFAGMGDQPVQDTE
                     TSSALISSHYLDEQDLSEKLKSELQWFELENKLLNLWEH"
     gene            27515..27805
                     /locus_tag="VVR63_001142"
     CDS             27515..27805
                     /locus_tag="VVR63_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000501069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6129166.1"
                     /translation="MGALGYYEGFVPYVSNQYKNQAEEEGKPLSDKYIFEKILGKTYA
                     AFKKDQINERVEKLGKLKPITINYNGKSEVIDSKEKLQELMNKAVKDEVAQI"
BASE COUNT         8825 a         4565 c         5938 g         8678 t
ORIGIN      
        1 gaaaaacgtg gactggtttc gtgtttggat tattaccttg aacgacatgc gttaaaagtt
       61 agttgaaccg ctgtatgccg aacggcacgt acggtggtgt gagaggggct agagattatc
      121 ccctactcga ttaactcccc tgaaatttat tttaattatg caaatttcac gtatttttga
      181 tgctgagacg acgatcctgg gaacttttca gatatttttt tgactatcta aatctatcat
      241 tagaaaagct tagagcgcca aaggatttga gcgtttttct gatttttaag actttttcca
      301 gtctcttttt cgattgaaga tgtaattatt ctactaacta actaacttct tagtactagc
      361 caacaacgat aatcataatt cctcctaaaa ttaggaataa taaaggcaat agtttttgtt
      421 ttttcatgta aaaaacctca cttttgtttt ctgctatttt atgctaaaat attaaaaatc
      481 aaatttaatt ccaaagtttg taactaaagg gggagcgcta catgtctaat tcatttgtca
      541 agttgttagt ctctcaatta tttgcaaatt tagcagatat tttctttaga gtaacaatca
      601 ttgctaacat atacattatt tcaaaatcag taattgccac atcactagtt cctatcttaa
      661 taggaatatc ctcttttgtt gcgagtcttt tagttccgtt ggttactaaa aggttagcgc
      721 taaatagggt tttatcttta tctcaatttg gaaagactat attattggcg atactggtag
      781 gaatgtttac cgtaatgcaa tccgtagcgc ctttggtgac ttatctattt gttgttgcaa
      841 tttccatact agatggtttt gcagcacccg tttcctatgc tattgtgcca cgctatgcga
      901 ccgatttggg taaggctaat tcagccttat caatgactgg tgaagctgtt caattgatag
      961 gttggggatt aggtggactc ttgtttgcaa caattggtct gttacctacc acgtttatca
     1021 ttttagtctt gtatatcatt tctagctttc tgatgttatt tcttcctaac gctgaagtgg
     1081 aggtgttaga gtcagaaact aatcttgaaa ttttactcaa aggttggaag ttagttgcta
     1141 gaaatcctag attaagactt tttgtatcag caaatttatt ggaaattttt tcaaatacga
     1201 tttgggtttc ttccattata cttgtttttg taacggagtt attaaataaa acggaaagtt
     1261 actggggata ttctaataca gcatactcta ttggtattat aattagtggc ttaattgctt
     1321 ttaggctatc tgaaaagttc cttgctgcta aatgggaaag tattcttttt cctcttgtag
     1381 ctatggcaat agtgacactg actattctat attttccaaa cgcacagatg tttttattat
     1441 tttcagcttt agttggtatg ttatcgcaac taaaagaagt tcctgaaagt gtatttcttc
     1501 aggaaacagt agaggaaaat catttagtta atgtctattc cgttcttgaa gtgatttcta
     1561 cattagcatt ttcagtattt gttttgctaa tgagctatat tactgagagt tttggtatta
     1621 gcatcagttt ttggctatca gccatttgtc tgatgataga agctatttta atttatatca
     1681 gacgagatta ttttaaatga gagagtggtt aaaaagtctt taaaaatcag aaaagcgcat
     1741 agtatcaggt gttgaaaaaa cttgatattg tgtgttttat tatgggaaga tttacttcat
     1801 tgtctcctga aatggagttt tgaagcagga tcactctatt tgaaaatata catagaaaaa
     1861 ccgcataatc cttaaaataa gctgaaatct attggaaaca tacggtaaac aattgaaaag
     1921 atactatata aagtggtaca atggtagaaa aataagctag taagaatcac tcttatttta
     1981 gcgaaaaatt acagaaatga atggtttttc ttgatgaaac agagaaaaga attgtacctc
     2041 tttcttggtc ggacagcctt gtattttctt atctttctag ggctgcttta cttctttagc
     2101 tatcttggtc agggtcaagg aagctttatc tataatgaat tttaacttga aggagaatcc
     2161 ctattgtgtc aaataaacca atagcagata tgattgaaac cattgagcat tttgctcaga
     2221 cacagcctag ctatcctgtc tataatgttt tggggcagga acacacttat ggcgatttaa
     2281 aggctgattc ggatagtttg gctgcagtca ttgaccaact aggcttgcct gagaagtctc
     2341 ctgtggttgt ttttggtggc caagaatatg aaatgttggc aacctttgta gcgctgacta
     2401 agtcaggtca tgcctacatt ccaattgata gccattcggc cttggagcga gtttcagcta
     2461 ttttagaagt agcagagcca agcttgatta ttgccatttc agcctttccc ttggagcagg
     2521 tttctacacc aatgataaat ctagctcagg ttcaagaagc ctttgcccaa gggaacaact
     2581 atgaaatcac gcatccagtc aagggagatg ataattacta cattatcttt acttctggta
     2641 cgactggtaa gcctaaggga gtgcagattt cacatgataa tctcctcagc tttacaaact
     2701 ggatgattac ggataaggaa tttgcgacac cgagtcgtcc gcaaatgctg gcacagccac
     2761 cttattcttt tgacttgtct gtcatgtatt gggcaccgac cttggcactt ggtggtacgc
     2821 ttttcactct tccttcagtc atcactcagg actttaagca actctttgcg gctatctttt
     2881 cattgccaat cgctatctgg acatcaacac catcctttgc agatatggcc atgttgtctg
     2941 aatacttcaa cagtgagaaa atgcctggaa tcacgcattt ctactttgat ggtgaagaat
     3001 tgacggtcaa aacagctcaa aaactgcgcg agcgtttccc aaatgcccgt atcatcaatg
     3061 cttacggccc aacagaagcg acagtagctc tgtcagcagt tgccgtgaca gacgagatgt
     3121 tagcgactct caaacgccta ccaatcggct ataccaaggc tgattctcca acctttatca
     3181 ttgacgagga aggaaataaa ctgccaaatg gcgaacaggg agaaatcatt gtttctgggc
     3241 cagctgtttc aaaaggttat atgaaaaatc ctgaaaaaac agcagaagcc ttctttgagt
     3301 ttgaaggtct gccagcctat cacacaggcg atgtgggaac catgacagat gagggcttgc
     3361 ttctctacgg cggacgcatg gacttccaga ttaagtttaa cggttaccgc attgagttag
     3421 aagatgtctc tcaaaacctc aacaagtctc gctttatcga atctgctgtc gcagtaccgc
     3481 gctataacaa ggaccacaag gtacaaaatc tattggctta tgtcatctta aaagacggtg
     3541 ttcgtgagca gtttgagcga gatatcgata ttaccaaggc catcaaggaa gacctgacag
     3601 acatcatgat gtcctatatg atgccatcta aattccttta ccgagacagt ttgccactaa
     3661 ctccaaatgg aaagattgac atcaaaggat tgattaacga ggtgaataag agatgatgga
     3721 gttttttcaa cagcttcctc atttagagcc atatggcaat cctcagtatt ttgtttatgt
     3781 gattgctgca accttgccca tctttatagg tctctttttc aagaaacgct ttgcctggta
     3841 tgaagtgttg gtaagtctct tctttattgt caccatgttg gtgggtggaa agaccaatca
     3901 actagctgcc ttgggtattt acctttgctg ggaaatattg ctcctgcttt tctacaagca
     3961 ttatcgaaaa agcaaggatg gcaagtgggt cttctactta gttagttttc tgtccctact
     4021 tccgattatc tttgtcaagg tgcaaccagc tatcaatgga acgcagtctt tgcttgggtt
     4081 cttgggaatt tcttacctta cctttcgttc ggttgggatt atcatcgagc tgagagatgg
     4141 agtgattaag gattttaccc tctgggaatt cctccgtttc cttctcttca tgccaacttt
     4201 ctcgagtggt ccaatcgatc gctttaagcg atttaatgaa aattatcagg ctattcctga
     4261 gcgagatgag ttgatggata tgctggatga atctgtccgc tatatcatgc ggggcttttt
     4321 gtataagttt atcctagctc atgttttagg agagacctta ctacctcctc tgaagaattt
     4381 agccttgcag tcaggtggct tctttaatct ctatgccttg gcagttatgt atacttttgg
     4441 tctggagctc ttctttgact ttgcaggtta ttctatgttt gctttggcca tctcaaactt
     4501 gatgggaatc cgtagcccta tcaactttaa caagcccttt ttatcaaggg atttaaagga
     4561 gttttggaat cgctggcata tgagtctgtc cttctggttc cgtgactttg tctttatgcg
     4621 aatggtgatg gtgttaacca gaaagaaagt ctttaaaaat cgtaatgtaa cctcaagcat
     4681 ggcctacatt gtaaatatgc tgattatggg attttggcat ggtgtgacct ggtactatat
     4741 cgcctatgga ctctttcatg gactaggctt ggtcatcaat gatgcctggg ttcgcaagaa
     4801 aaaaacgctc aataaggaac ggaaaaaagc agggaaggct gccctacctg agaatcgctg
     4861 gattcagttg cttggcatgg ttgtcacttt ccatgttgtc atgttgtcat tcttaatctt
     4921 ttctggattc ttgaataatc tatggtttaa aaaataaaag gaaataaaat atggatatca
     4981 aatcagaagt tattgaaatt attgatgagt tgtttatgga agatgtttct gacatgatgg
     5041 atgaagatct ttttgatgca ggtgtcttgg atagtatggg aacggttgag ttgattgtgg
     5101 agattgagaa ccgttttgac attcgtgtcc ctgtaacaga gtttggtcgt gacgactgga
     5161 atacagctaa taaaatcata gctggtattg tggagctaca aaatgcttaa acgcttatgg
     5221 atgatcttcg gaccggtctt gatcgctggt ttgttggttt ttctgctcat tttcttttat
     5281 cctactgaga tgcatcataa tctaggagct gaaaagcgtt cagcagtggc tactactatc
     5341 gatagtttta aggagcgaag tcaaaaagtc agagcactat ctgatccaaa tgtgcatttt
     5401 gttcccttct ttggctctag tgaatggctt cgttttgacg gtgctcatcc tgcggtatta
     5461 gctgagaaat acaatcgttc ctaccgtcct tatcttttag gacagggggg agctgcatcg
     5521 cttaaccaat attttggaat gcaacagatg ttaccacagc tggagaataa acaagttgtg
     5581 tatgttatct cacctcagtg gttcagtaaa aatggctatg atccagcagc cttccagcag
     5641 tattttaatg gagaccagtt gactagtttt ctgaaacatc aatctgggga tcaggctagt
     5701 caatatgcag cgactcgctt actgcaacag ttcccaaacg tagctatgaa ggacctggtt
     5761 cagaagttgg caagtaaagg agaattgtcg acagcagaca atgaaatgat tgaattattg
     5821 gctcgtttta atgaacgcca agcctccttt tttggtcagt tttcggttag aggctatgtt
     5881 aactacgata agcatgtagc taagtattta aaaatcttgc cagaccagtt ttcttatcaa
     5941 gcaatagaag atgttgtcaa agcagatgct gaaaaaaata cttccaataa tgagatggga
     6001 atggaaaatt atttctataa tgagcagatc aagaaggatt tgaagaaatt aaaggattct
     6061 cagaaaagct ttacctatct caagtcgcca gagtataatg acttgcagtt ggttttaaca
     6121 cagttttcta aatctaaggt aaacccgatt tttatcattc cacctgttaa taaaaaatgg
     6181 atggactatg ctggtctacg agaggatatg taccaacaaa cggtgcagaa gattcgctac
     6241 cagttagaaa gtcaaggttt taccaatata gcagattttt ctaaggacgg cggggagcct
     6301 ttctttatga aggacaccat tcaccttggt tggttgggtt ggttggcttt tgacaaggca
     6361 gttgatcctt tcctatccaa tcccacacca gctccgactt accatctgaa tgagcgcttt
     6421 ttcagcaaag attgggcgac ttatgatgga gatgtcaaag aatttcaata gataatataa
     6481 tatagaagag ttcaagaatg aaactagttt tcacgttttt tcttgactct ttttttgctt
     6541 gtgatataat taactggtaa acaaaatgtc aaagaatagt atttttctct taaaaaagag
     6601 aagtctaaaa ggaaaggagt cagatatgag acagctagca aaggatatcg atgctttttt
     6661 gaatgaggtg attttgcagg cggaaaatca gcatgaaatc ctaataggtc attgcactag
     6721 tgaggtggcc ctgaccaata ctcaggagca tatccttatg ctcttgtcag aggaatcttt
     6781 aacaaattca gaattggccc gtcgtctcaa tgtcagtcag gcggcagtta ccaaggccat
     6841 taagtctttg gtcaaggaag ggatgttgga aacatctaaa gattctaaag atgcgcgtgt
     6901 gattttttat cagttgactg acttggctcg tccaatcgct gaggagcacc accatcacca
     6961 tgagcataca cttttaacct atgaacaagt ggcgactcag tttactccaa atgaacaaaa
     7021 agtgattcag cggtttttga ctgctttagt aggagaaatc aaataatgag atatattacg
     7081 gtagaggatt tgtccttcta ttatgataag gagcctgttc ttgaacatat caattatagt
     7141 gttgatagtg gggaatttgt taccttgact ggggaaaatg gagcggctaa gacgacgctc
     7201 atcaaggcta gtcttggaat tctgcaacca cgcattggaa aggtggctat ttcaaagaca
     7261 aatacgcaag gtaagaaatt gagaatagcc tatcttcctc aacaaattgc cagttttaat
     7321 gctggttttc caagtacggt ctatgaattt gtcaagtcgg gtcgctatcc gagaaaaggc
     7381 tggttccgtc gtttgaatgc tcatgatgag gagcatatca aggctagtct ggactcagtt
     7441 ggcatgtggg aacatcgaga caaacgcttg gggtctctat ctgggggaca aaagcagcga
     7501 gcggtaattg cgcgtatgtt tgcttctgac cctgatgtgt ttatcctaga cgagccgaca
     7561 acggggatgg atgcaggaag taaaaatgaa ttttacgaac tcatgcacca cagcgcccat
     7621 catcatggca aggctgtttt gatgattacc catgaccctg aagaagttaa ggattatgcg
     7681 gatcgcaata ttcatctagt ccgtaaccaa gactcgccat ggcgttgttt caatgttcat
     7741 gagaatggcc aggaggtggg ccatgcttag tttattatct tacgacttta tacaacgcgc
     7801 ctttttggcg gttattgcta tgagtctttt ctcaccggta ttgggaacct tcctcatctt
     7861 gcgtcgtcag agtttgatga gtgataccct tagccacgtc tcactttcag gtgtagcctt
     7921 tggtctggtt ttggggattt ctccaactgt ttctactatt gccattgtct tgattgcggc
     7981 ggtctttctg gagtatctcc gtacggttta caagagcttt atggaaatcg ggacagctat
     8041 cctcatgtca acaggtctgg ctgtttctct gattgtcatg agcaagggta aaagctcgag
     8101 ttcaatgagt ttggaccaat atctctttgg ttcgatcgtg actatcagtg aagaacaggt
     8161 catttccctc tttgttattg cggcggttgt tttgattttg acctttctct ttcttcgtcc
     8221 tatgtatatc ttaacttttg acgaagatac ggcctttgtg gatggcttgc cagttcgtac
     8281 catgtccatt ctttttaaca tggtgacagg ggtggctatt gcccttatga ttcctgcagc
     8341 aggagctctt ctggtatcga ccattatggt cttgccagct agtattgccc tgcgtctggg
     8401 gaaaaacttt aaatcggtta tgctgcttgc cagtgcgatt ggctttttgg gaatggtagc
     8461 aggactttac atttcctact atgcagaaac acctgcaagt gcaagtatta ccattatttt
     8521 tgtaactgtc tttatactaa tcagtttagt aagacgtttt atcaaatagg agacgaacgt
     8581 gaaaaaaatt agcttattac tagccagtct atgtgccttg tttttagtgg cttgttccaa
     8641 tcaaaaacag gcagatggta aactcaatat cgtgacaacc ttttaccctg tctatgaatt
     8701 taccaagcaa gtcgcaggag atacggctaa tgtagaactc ctaatcggtg ctgggacaga
     8761 acctcatgaa tacgaaccat ctgccaaggc agttgccaaa atccaagatg cagatacctt
     8821 cgtttatgaa aatgaaaaca tggaaacatg ggtacctaaa ttgctagata ccttggataa
     8881 gaaaaaagtg aaaaccatca aggcgacagg cgatatgttg ctcttgccag gtggcgagga
     8941 agaagaggga gaccatgacc atggagaaga aggtcatcac catgagtttg atccccatgt
     9001 ttggttatca ccagttcgtg ccattaaact agtagagcac attcgtgaca gcttgtcagc
     9061 agattatcct gataaaaaag agacctttga gaagaatgca gctgcctata tcgaaaaatt
     9121 gcaagccttg gataaggctt acgcagaagg cttgtctcaa gcaaaacaaa agagctttgt
     9181 gactcaacac gcagccttta actatcttgc cttggactat ggactcaaac aagtcgcaat
     9241 ctcaggactt tctccagatg tagagccatc agctgctcgc ttggcagaat tgacagagta
     9301 tgtcaagaaa aataaaatcg cctatatcta ttttgaagaa aatgcctcac aagcccttgc
     9361 taacacactt tcaaaagaag caggtgtcaa aactgatgtc ctcaatcctt tagaaagtct
     9421 gacagaagag gacaccaagg ctggagaaaa ttacatctct atcatggaga aaaacctcaa
     9481 ggctttgaaa caaacaacag accaagaagg cccagcaatc gagcctgaaa aggcagagga
     9541 taccaagaca gtccaaaatg gttacttcga ggatgcagct gtcaaggacc gcaccttgag
     9601 tgactatgca ggtaactggc aatcagttta tcctttcctt gaagacggca cgtttgacca
     9661 agtctttgac tacaaggcta agttgactgg taagatgacc caggctgagt acaaggctta
     9721 ctatacaaaa ggctatcaga cagatgtgac taagattaac attactgata atactatgga
     9781 atttgttcaa ggtggacaaa gcaagaaata tacttacaag tatgtcggta agaaaatttt
     9841 gacttacaag aaaggcaatc gtggcgtgcg tttcctcttt gaagccacag atgctgacgc
     9901 tggacaattc aagtatgttc agtttagtga ccacaatgtt gccccagtta aggcagaaca
     9961 tttccatatc ttttttggag gtacaagcca agaagctcta tttgaagaaa tggataattg
    10021 gccaacctac tacccagata acctatctgg ccaagaaatc gctcaagaaa tgttggcgca
    10081 ttaatgagaa atcgactagt tcataagagc tagtcggttt ttgggtacta gatggctaac
    10141 ttcattatag acttttcaga actaaggaac tttaaaaaaa taaataaaac tcttgaaata
    10201 tctggactta tatgctagaa tgtagttagt gtataaggtt cattagaaca ccaaagcccc
    10261 taactagtgc catagttaag ggcttttttg acgtatctta gcgatttaac gggtgtttat
    10321 aggctagtca gtcggtctac ttcttaccat ctagccattt gcagacgaaa tacaagataa
    10381 ttccagctat aacatctgct ataatagtaa gagcaagctc tggtataagg ctcattagtt
    10441 tcacctcctc tcacgaaccg taaggaaggt aatcggtaac cgatgacaaa agtattatac
    10501 cacactaaat ttagatcatc aacctcactt aatgcttgaa ctattgtaga ttatatgcta
    10561 aaatgtagtt aattgataag gttcattaga acaccaaagc ccctaactat ggccgtagtt
    10621 aagggctttt ttgacgtatc ttagcgattt aacgggtgtt tataggctag tcactcggtc
    10681 tactccttac tatctagcca tctgcagacg aaatacaaga taattccagc tataacatcc
    10741 gctataatag taagagcgag ctctatgata aggctcatta gtttcacctc ctctcacgaa
    10801 cccataggaa cgtaatcggt aaccgatgac aaaaatagta taccacaata catttagatc
    10861 atcaaggtca cttaattctt gaaatatagg gtctaggcga caaagtcttt aaaatcagaa
    10921 aaacgcataa tatcaggtgt gcaaaaactt gatactatgc gttttattgt gggaaggttt
    10981 actccatttt ctcctgaaat tgagtttttg tccagcctct gtttttagaa ttgctaagaa
    11041 aataatgtca tgtggtgaat atttgtaaat cagtcagcag acagaacgaa tactcttcga
    11101 aaatctcttc acatcatgtc agcttcgtct tgccgtgtcc atgggggact tgacttcatc
    11161 agttttcaaa tctgtacttt gagcaagctg agactagctt cctatttgat tttcattgaa
    11221 tatcagaaac ccattctcca tcaaataatt cgactgcgtc taataatttt tgatttggca
    11281 aggtgtcaga aataaaggtt gtgtatttgg agaggggatt aattttaaaa aatccagtct
    11341 tgtaaaattt agaactatca atcagtaaga tggtttcatg ggctttgtca ataatattct
    11401 tttttgaaat agcttggctg agagaagctt cataaacata ttggtcatca atacctcttg
    11461 ctgaacaaaa tgctaaatcg atattaaaat gatctaataa agaattttcc ttatcatagt
    11521 tgaccacgga acaggattga tgtttgacct cgccagatgt gataaagatt ttggagctat
    11581 ctttaacagt ttcagatagg gtttgtgcag tatgtaaacc atttgtaaaa ataatcaaat
    11641 tatcaagttc agaaagatag ggacaaagtt cgtagacagt cgtactggaa tccagataaa
    11701 tacacatgcc tgaccgaata aagtctttag cgagactagc gattagtctt ttttgcctag
    11761 tactttctcc ttcccgtatt tgatgagaaa gttcaattgt gttcatagag gacagggtca
    11821 cgtatccgtg ctttcttttg ataagacctt gattttctaa gaaaattaaa tcacgacgta
    11881 aggtacttgt gctggagaaa gtgatttctg ccagctcttt tacggcaatt ctttttttct
    11941 ttttaataat ttcaatcaat tcaagtacac gttcatcttt tatcataagc tcctcctaat
    12001 ttatcatttc aactatatta tagcacaaat tggaggaatg tgaattattt ttatgaatat
    12061 tgggttaaca tttgaacatt attcaagtaa gcgttcacat attgaaaaaa taaaacgtgg
    12121 ggattataat aaagttaatc aaggacgaag agagaagaaa aatggaagcg gttttagcaa
    12181 tagatttagg tgcgacttct ggaagagcaa tcgttggtta cctttctgaa aataaactgg
    12241 taatggaaga aataaatcgc ttttctaatc tacctattag agtaaaaggg catttatctt
    12301 gggatattga ctttctacta gctaaaattc ttgaaagtat ccgcttggct aatactagtt
    12361 acaagatttt atctatcggt attgacacat ggggagttga ttttggactg attgataatg
    12421 aaggtaagct gttattacaa cctgttcatt atcgtgatga aagaacaaag ggagtgttaa
    12481 aggaaatatc tgaaatgact gaattagaaa aactgtattc agagacagga aatcagatta
    12541 tggagataaa taccttgttt caactcttta aggcacgtca agaatctcct gactctttct
    12601 ataagaccaa taagattctt ttaatgccag atttgtttaa ttatctcttg acaggtaagt
    12661 tttctacaga aaaaagcatt gcttcaacaa ctcaattatt tgatcctagg agtcaaaatt
    12721 ggaatcagaa tatcttaaaa ctatttgaat tggattcatc tttacttcct gaaattgttt
    12781 cagagggaaa tgttcttgga aggataaaaa aggagtatgg tttaggcgat attcctgttg
    12841 tgaatgtttg tagtcatgat acagcaagtg cgattgtctc agtacctaag acagaaggta
    12901 gtttatttat ttcatcaggt acttggtctt tggttggagt ggaacttact tcaccgattc
    12961 ttactaccga atccttcagt tatggattta caaatgaagt cggtaaagat ggagagatta
    13021 catttctgaa gaattgtaca gggttgtgga tcatagagga actaagacgt tcatttgaac
    13081 gaagagggaa agcctattct tttgatgata ttaggacaat ggtggagaaa gaaaaagaaa
    13141 atcttcctct gattgatact gaatcaactg aatttgcaac agaatctgat atgcacaaga
    13201 ctttgacaga atatctagct tatcatcatg aaactagaga gtggacagat ggacaactat
    13261 ttaagattgt ttatgaaagc ctagctgaaa cgtataggaa agcgatagag ttactagaag
    13321 aactaactca taaggtttat aagaggatat atgtgattgg aggaggtgct agagccagtt
    13381 actttaacca aatgattgct gatagaactg gtaaagaggt tcttacaggt tcgactgagg
    13441 gtacagctgt ggggaatatt gttgtgcagc tcatagctat gggacaatta aaagggatgg
    13501 aagaagctca ccatgttatt gaggagtttc tacaattaga gagttattac tcccaaaaga
    13561 attaaaaaga ttgagagttt gtaaatttgc ctccctcccc cttcttaagt tttgtacaag
    13621 aaggggggat aattggtgaa ttgaaaaata tttagtgttt tgatatgagg aggacaagaa
    13681 tgtcagatgt aaaacaagaa ttaattaagt atggcaagaa gctagtagaa acagatttga
    13741 cgaaaggaac aggtgggaat ctcagtgttt tcgatcgtga aaaacaattg atggcaatta
    13801 ccccgtcggg tattgatttc tttgaaatca aagaatccga tattgtagtg atggatatta
    13861 atggaaatgt tgtagaggga gaacgcttgc catctagcga atggtatatg catttgattc
    13921 aatatcaaac tcgtgatgat atcgatgcaa ttatccatgc tcatacaact tatgcaacag
    13981 tattagcttg tctcagagaa ccacttccgg ctagtcatta tatgattgca gtggcaggga
    14041 aagatgttcg ggtagctgag tatgcaacat atggtacgaa agaattggct gtgaatgcag
    14101 ctaaagcaat ggaaggtcgt agagcagttt tactagcgaa tcatggaatt ttagcaggtg
    14161 cacaaaattt attgaatgca tttaatattg ttgaagaagt tgaatattgt gcaaaaattt
    14221 attgtttagc taagaatttt ggagagccag tagttcttcc tgatgaggag atggatttaa
    14281 tggcagaaaa atttaaaaca tacggtcaga gaaaataggg aggatattaa tgttaaaaca
    14341 tataccgaaa aatatttctc cagatttatt gaagacttta atggaaatgg gacatggaga
    14401 tgaaatagta ttagctgacg cgaattatcc ttctgcctca tgtgcaaata agctaattcg
    14461 ttgtgatggc gtaaatattc cagaattatt agattccatt ctgtatttaa tgccattaga
    14521 tagttacgtc gatagttcaa ttcagtttat gaacgttgtt tcgggtgatg atattcctaa
    14581 gatatggggt acctatagac agatgattga aggtcatggt acagatctta aaacgattac
    14641 ttatcttaga agagaagact tttatgaacg tagtaagaaa gcttatgcta ttgttgctac
    14701 aggagaaact tcactttatg ctaatattat ccttaagaaa ggagtagttg ttgaaagaga
    14761 aaatgtttaa tagaggaatt ttagttgcca gtcatggtaa ttttgctagc ggagctctca
    14821 tgaccgcaga aatgtttgtt ggtgagacaa caaatgatag agttaggaca ttaggtttga
    14881 tgcctggaga gaatattgta gagtttgaac attattttaa aaatcaagta aatgaactgt
    14941 tagactcaaa tcaagaggtt atcgttttga ctgacttgat tggaggaagt cctaataatg
    15001 tggctttgtc acggttttta aatttggatt cagttgatat tgtaacaggg tttaatatcc
    15061 ctctcctagt ggaattaata tcaagttatg attcaaaaat caatttagaa gaaattgttc
    15121 aaaatgctca aaatagtttg tttaatgtta aacaacaact taacgtagag gaggaagagg
    15181 atttatgtct atagagtttg ttcgtattga tgaccgtctg gtacatggtc aagttgtcac
    15241 tacgtggcta aaaaagtatg atattgagca agttatcatt gttaatgatc gcatctcaga
    15301 agataaaaca cgacaatcta ttttaaagat ttctgcaccg gtaggtttaa aaattgtttt
    15361 ctttagtgta aaacggtttg tggaagtttt aaactctgtg ccaataaaaa agagaacaat
    15421 gctgatatat acaaatccaa aagatgtgta tgattctatt gaaggaaatt taaaattgga
    15481 gtacctcaat gtaggacaga tgagtaaaac ggaggaaaat gaaaaggtaa cgggaggtgt
    15541 agctctaggt gaagaagaca aatattattt taagaaaata gttgataagg gaacgagagt
    15601 tgaaattcaa atggttccta atgataaagt tacaatgttg gaaaaatttt tataaaaata
    15661 atttaaggag gtacagtata tgctattcac acaagcatta ctggtgacat tagttgggat
    15721 tattgccact attgactata atggaccgtt atttatgatt caccgtccgt tagttacaag
    15781 tgcaatggtt ggcttagtct taggagattt cacccaaggt gttcttattg gttcagctct
    15841 tgaattaact tggctcggtg taacaggtat tggaggttac actccaccag atactatttc
    15901 aggtgcgatt attggtactg catttggtat tttgtctggt caaggagaaa ctgctggtat
    15961 cgctatagca gttccaattg cagttgctac tcaacagttg gatgttcttg caaaaacttt
    16021 agatgtttat tttgtgaaaa aagctgataa tgatgctaaa aacggagatt attcaaagat
    16081 cggtttttat cattattcaa gtttggtttt aatcacttta tttaaaattg taccaatttt
    16141 cctagctatt atgcttggag gggaatatgt ggcagacttg tttgctaagg ttccaccaat
    16201 cgttatgcag ggacttaact ctgcaggtgc tttactacct tcaattggtt ttggtatgct
    16261 tttaaatatg atgctcaaga aaaatatgtg ggtattcttg ttgattggat tcatttgttc
    16321 tgtgtatgga ggaatgtcaa ccattgggat ctcactagtt ggtattgcgg tagcatactt
    16381 ctacgatatg attggaagta aaccacaaga aacaacttca agtagtgatg ttgaggagga
    16441 tcttgatcta tgatgaataa taaagtaact aaagttgaac ttaaaaaagt tttcaaacga
    16501 agttttatgt atggttcttc atggaactat gagagaatgc agaacctagg ttttctatat
    16561 acaattcttc cagtattgaa aaaactatac ccagacaaag attcagcttc tcctgcaatg
    16621 aaacgtcacc ttgagttttt caatactcat caaacagcgg caccatttat tcttggagtt
    16681 acttccgcta tggaagaaca agaaggaaat gaaggtgcag cttcaattac tggtattaaa
    16741 gttggcttga tggggccact ggctggtcta ggagatagtt tgttctggct gacactagtt
    16801 cctatctgtt ttagtattgg tgcgtcttat tctaaagacg gcggtgcttt aggtatcttt
    16861 atcgccttaa tattgtttaa tattattaat attcctgtta aatatttcgg tttgaaatat
    16921 gggtatacta agggttctag tcttatccaa gaaaataata caaaaggaac attgaatcgc
    16981 gttacgagta tggcgacagc attagggcta gtactagtgg gtggtttgat tccatcaatg
    17041 gttggtatta attttggatt agaatttaag cagggggaac ttgttatttc tgttcaagaa
    17101 atgattacaa aattaattcc aggatttatc cctatggctt tgactttatt aatgtgtaaa
    17161 ttaattagaa aaggaaagaa tccggttgta ctaatcttta gtgttatggc tattggagtt
    17221 atcctagttg ttttaggaat tttgaagtag tagaaagtgt ggaggtggta tttgggatat
    17281 cacctccatt ttggaagaga ggtaaagagt gaaattatgg tataagaaag ctgccgcaaa
    17341 ttggaatgaa gccttgccga ttgggaacgg tcatttaggt ggtatgattt atggttcagc
    17401 tacaaaagaa tgtattcaac taaacgatga gactatttgg tatagaggaa agtcagatag
    17461 aaataatcca gactcactat tgcatcttaa aaaaattcgg gaatatcttt tagatggaga
    17521 aattcagaaa gccgaagaat tgataaagtt aacaatgttt gctaccccaa gagatcaaag
    17581 ccactatgaa ttacttgggg aactttgcat tgagcatata gatattcagt cttgtgctct
    17641 ttcattgtat gaaagagagc tagatttaga tacagctatt tctaatgttg tgtttgagcc
    17701 taatagttgt aatttacaaa taaaaagaga atattttacg agttttaata agaatatttt
    17761 atgttgccgt atagtgtcat cagttcaaaa cacattaaat ttaaacatta atttgggtag
    17821 aaataaacgg tttaatgacg aagtatctaa actggattca agtacaattt taatgtcggc
    17881 ctctgctgga ggtagaaaag gtgttcagtt taaagtagta tgtcattcta aggttacgga
    17941 tggtgaagta agtgtattgg gagagacaat agttattcgg aatgctacag aggtatttct
    18001 ttatctcaaa tcaatgacgg attattgggg aaatatagat atttcttctc ttcagggaga
    18061 atttagtagt attgattact ttacagaaaa agatgaacat gtaaaaaaat atcaggagca
    18121 atttaataga gttgatttta aactagacta tagtaaaggt tgtcttagca ttccaacgaa
    18181 tctacttctt gaaaacacta aaaagtatag taactacttg actaacttgt tatttcatta
    18241 tggaagatat ctgttaatat cgtctagtca accgaatggt ttacctgcca atcttcaagg
    18301 aatatggtgt gatgaattaa atccaatttg gggttctaaa tatacgatta atattaatac
    18361 tcaaatgaat tattggatgg taggtccatg tgatttacca gaagtagaat atccattatt
    18421 tgatatgctc gaaagaatga gagaaccggg aagactaacc gctaagaaaa tgtatggagc
    18481 tagaggtttt acagcacatc ataatacgga tggttttggc gatacggctc cccaatctca
    18541 tgccatgggg gctgcaattt gggtattaac tattccatgg ttatgtactc atatttggga
    18601 acactattta tatttccaag atgagcgtat tcttacggaa cattttgaaa tgataaaaga
    18661 agcatttctt ttctttgaag attatttatt tgaggtggat ggctacttga tgacaggtcc
    18721 aagtgtctca ccggaaaata aatatcgctt aaaaaatggt attgaaggaa atgcttgtct
    18781 atcatctaca attgataatc aaattctaag atatttttgt gattcatgca ttggcattgc
    18841 aaaacaatta ggagacaatt cggattttat tagtcgtgtg aaggagttaa aaaagaaatt
    18901 acctagaaca aaaataggta gtaatgggca aatacaagaa tggctagagg attatgaaga
    18961 agtagagcct ggtcatagac acatttcacc tctatttggg ctttatcctt ataatgagat
    19021 tgatattcat aaaactccgg aattagcaga agcagctaaa atcactatca ataggagatt
    19081 atcaaacgct aactttttat cttcacagga tagggagcaa gcgattaata attggttagt
    19141 aagtggtttg catgctagta cacaaacagg ttggagtgct gcatggctga ttcatttttt
    19201 tgcgagacta tatcaaggtg aacctgctta taaccagatt aatggtttgt taaataatgc
    19261 gactcttggc aatttatttc ttgaccatcc accatttcaa attgatggta atttaggttt
    19321 ggtgagtgga atttgtgaat tattagtaca gagccatcat aattggttat cactaattcc
    19381 agctttacct tctgcttggt cagaaggaga agtgaaaggt ttcagagtaa gaggaggata
    19441 taaggtatcg tttgcttgga aaaatgggga tataacattc ctaaaattgg aaggaggaaa
    19501 caaagatcaa aaagtaagag taagaatata tggcaaaaat actgatgtac aaaatattga
    19561 attggtattt aattcagaaa aaattattga gttaaatttt taggtataag tcatgaataa
    19621 agaaaaaata aaaagaaaat taatcacaat attgtttgta tgtattggga tgttatgttt
    19681 tggattgtta gcaggagtta aggctgataa tcgtgttcaa atgagaacga cgattaataa
    19741 tgaatcgcca ttgttgcttt ctccgttgta tggcaatgat aatggtaacg gattatggtg
    19801 ggggaacaca ttgaagggag catgggaagc tattcctgaa gatgtaaagc catatgcagc
    19861 gattgaactt catcctgcaa aagtctgtaa accaacaagt tgtattccac gagatacgaa
    19921 agaattgaga gaatggtatg tcaagatgtt ggaggaagct caaagtctaa acattccagt
    19981 tttcttggtt attatgtcgg ctggagagcg taatacagtt cctccagagt ggttagatga
    20041 acaattccaa aagtatagtg tgttaaaagg tgttttaaat attgagaatt attggattta
    20101 caataaccag ttagctccgc atagtgctaa atatttggaa gtttgtgcca aatatggagc
    20161 gcattttatc tggcatgatc atgaaaaatg gttctgggaa actattatga atgatccgac
    20221 attctttgaa gcgagtcaaa aatatcataa aaatttggtg ttggcaacta aaaatacgcc
    20281 aataagagat gatgcgggta cagattctat cgttagtgga ttttggttga gtggcttatg
    20341 tgataactgg ggctcatcaa cagatacatg gaaatggtgg gaaaaacatt atacaaacac
    20401 atttgaaact ggaagagcta gggatatgag atcctatgca tcggaaccag aatcaatgat
    20461 tgctatggaa atgatgaatg tatatactgg gggaggcaca gtttataatt ttgaatgtgc
    20521 cgcgtataca tttatgacaa atgatgtacc aactccagca tttactaaag gtattattcc
    20581 tttctttaga catgctatac aaaatccagc tccaagtaag gaagaagttg taaatagaac
    20641 aaaagctgta ttttggaatg gagaaggtag gattagttca ttaaacggat tttatcaagg
    20701 actttattcg aatgatgaaa caatgccttt atataataat gggagatatc atattcttcc
    20761 tgtaatacat gagaaaattg ataaggaaaa gatttcatct atattcccta atgcaaaaat
    20821 tttgactaaa aatagtgagg aattgtctag taaagtcaac tatttaaact cgctttatcc
    20881 aaaactttat gaaggagatg ggtatgctca gcgtgtaggt aattcctggt atatttataa
    20941 tagtaatgct aatatcaata aaaatcagca agtaatgttg cctatgtata ctaataatac
    21001 aaagtcgtta tcgttagatt tgacgccaca tacttacgct gttgttaaag aaaatccaaa
    21061 taatttacat attttattga acaattacag gacagataag acagctatgt gggcattatc
    21121 aggaaatttt gatgcatcaa aaagttggaa gaaagaagaa ttagagttag cgaactggat
    21181 aagcaaaaat tattccatca atcctgtaga taatgacttt aggacaacaa cacttacatt
    21241 aaaagggcat actggtcata aacctcagat aaatataagt ggcgataaaa atcattatac
    21301 ttatacagaa aattgggatg agaataccca tgtttatacc attacggtta atcataatgg
    21361 aatggtagag atgtctataa atactgaagg gacaggccca gtccctttcc caacaccaga
    21421 taaatttaat gatggtaatt tgaatatagc atatgcaaaa ccaacaacac aaagttctgt
    21481 agattacaat ggagacccta atagagctgt ggatggtaac agaaatggta attttaactc
    21541 tggttcggta acacacacta gggcagataa tccctcttgg tgggaagtcg atttgaaaaa
    21601 aatggataaa gttgggcttg ttaaaattta taatcgcaca gatgctgaga ctcaacgtct
    21661 atctaatttt gatgtgattc tatatgacaa taatagaaac gaagttgcta agaaacatgt
    21721 taataatttg tcgggtgaat ctgttagtct agatttcaaa gaaaaaggag caaggtatat
    21781 taaagttaaa ttactaacga gtggagtgcc tttgagttta gcagaagtag aggtttttag
    21841 agaatcagat ggtaagcaat ctgaagagga tatagataaa ataacagaag ataaagtagt
    21901 ctctacaaat aaggtagcta ctcaaagttc aaccaattat gagggtgtag ctgctttagc
    21961 agttgatggt aataaagatg gagattacgg acatcattcg gtgactcata ctaaggcaga
    22021 ttctaacgct tggtggcagg tcgatctggg agaagagttt acggtttcta aagttgatat
    22081 ttataataga acagatgccg aacctcagcg tttatctaat tttgatgtta tttttctatc
    22141 ttcatcagga gaagaagttt ttagaagaca ttttgataaa gtagttgatg gtttgttatc
    22201 tttaaaagta ccttctgtag gggctaagct agtcaaaata gaattaaaat cagcagctat
    22261 tccgttaagt ttagcggaag ttgaagtcta tggttcaaag agaactccga agaaactttc
    22321 taatattgca ttaaccaaag aaactcgaca gagttcaacg gattacaatg gtttttctcg
    22381 tctagcagtt gatggaaata aaaacggaga ttatggtcat cattcagtga ctcataccaa
    22441 aggagattct ccttcatggt gggagataga tttagcacaa accgaagaat tagaaaagtt
    22501 aattatttat aatagaacag atgctgaaat tcagagatta tcaaattttg atattattat
    22561 atatgattca aataatcatg aagtttttaa acaacatatt gacagtttag aaagcaataa
    22621 tctatccata gacttaaaag ggctgaaggg aaaaaaggtt agaatttctt tgagaaacgc
    22681 aggaattcct ttaagtttgg cagaggtaga ggtttatact tataagtaat tttaaaaatt
    22741 atcatcggta gtatgaaaga aacagaaaaa taagaggaaa atagtatgat tcaacatcca
    22801 cgtattggta ttcgtccgac tattgatggt cgtcgtcaag gtgtacgcga atcacttgaa
    22861 gtacaaacaa tgaacatggc taaaagtgtg gcagatttga tttcaagcac attgaaatat
    22921 ccagatgggg aacctgtgga atgtgtgatt tctccatcta ccattggtcg tgttccagag
    22981 gctgcagctt cccatgagtt gtttaaaaaa tcaaatgttt gcgcaacaat tacagttaca
    23041 ccatgctggt gttatggtag tgaaactatg gatatgtctc cagatattcc tcatgctatt
    23101 tggggattta atgggacaga acgcccagga gctgtctatc ttgcagctgt actagcttca
    23161 catgctcaaa aagggattcc agcctttggg atttatggta gagatgttca ggaagctaat
    23221 gatacagata ttccagaaga tgtcaaagaa aaacttttac gttatgcgcg tgcagctctt
    23281 gcaactggct tgatgagaga cactgcttac ctatcaatgg gtagtgtttc gatggggatt
    23341 ggtggttcta ttgtaaatcc ggatttcttc caagaatact taggaatgcg aaatgaatcg
    23401 gtagatatga cggagttcac acgccgtatg gaccgtggta tttacgaccc tgaagagttt
    23461 gaacgtgcta tggtttgggt aaaagaacat atcaaagaag gagttgaccg aaatcgtgag
    23521 gatttgattc tttctaaaga agagaaagaa aaacaatggg aatttgttat taagatgttc
    23581 atgattggac gtgacttaat ggttggtaac ccaagacttg ctgaacttgg ttttgaggaa
    23641 gaagcagttg gtcaccatgc tttagtagct ggtttccaag gtcaacgtca gtggacagac
    23701 cattttccaa atggggactt tatggaaact ttcctcaata ctcagtttga ctggaatggt
    23761 attcgaaaac catttgtatt tgcgacagag aatgattcac taaatggtgt gtctatgctc
    23821 tttaattatc tattaacaaa tactccacaa atctttgctg atgtgcgtac ttattggagt
    23881 ccagaggctg ttgaacgtgt aacaggatat actttagagg gtcgtgctgc agctggattc
    23941 ttacatctaa tcaactctgg atcttgtaca ttggatggta caggtcaagc tactcgagat
    24001 ggcaaacctg ttatgaaacc attctgggag ttggatgaaa gtgaagtaca ggctatgctt
    24061 gaaaatacag acttcccacc agcaaaccgc gaatacttcc gtggaggagg attctcaact
    24121 cgtttcttga cgaaggggga tatgccagta acaatggtac gtctcaatct tctaaaaggg
    24181 gttggtccag tgctacaaat tgcagaaggt tacacacttg aacttcctga agatgttcac
    24241 catactttag ataatcgtac agatccagga tggccaacta cttggtttgc tccacgtttg
    24301 acaggaaaag gtgctttcaa gtctgtctat gacgtcatga ataattgggg agctaatcac
    24361 ggagccataa catatggcca cattggagca gacttgatta ccctggcttc tatgttgaga
    24421 attcctgtca atatgcataa tgtacctgag gaagatatct ttagacctaa aaattggtcc
    24481 ttatttggaa cagaagatct agaatcagca gactatcgtg catgtcagtt gttgggacca
    24541 ctacataaat aaaacttgtt tatataggag gtaaacttac gtccctccta tccttttaaa
    24601 aatatttgtt aaacaattca caaataattg aaaacgaata caaaaagtaa tataatgatg
    24661 ttaaatagat agcgcaaagg cgcaggagga aaattatatg gctacatttt atgttccggc
    24721 agtcaacctt attggtaaag gtgttgtaaa tgaagtgggt ccttatatca aggaacttgg
    24781 ctataaaaag gcacttttgg tgacagataa gtacatcgaa ggcagtgata ttttacctaa
    24841 gactttaaaa ccactggata cagaaggaat cgaatatgtc atctttagcg atgtagagcc
    24901 aaaccctact tgtaaaaatg tcacagatgg ggtagctgct ttgcaagaac atggctgtga
    24961 ctttatcatc agtcttggcg ggggttctcc acaggatgca gctagttgta tttctatcat
    25021 ggctacaaat ggtggaagac cacaggatta tgaagggctt cataagtctg ctaaaaaagg
    25081 cttgccagtt gtggcgatca atacaacggc aggtacatca gcagaaatta ccattaacta
    25141 tgtgattact gatgaagaac gcaaggttaa gatggtaatg gttgacaaga atagccttgc
    25201 tcttatctct gttaatgacc cggaactcat gctttccaaa cctaaaggcc tgactgctgc
    25261 tactggtatg gatgctctga ctcacgctgt tgaagctttg gtaacacctg gtgcttatga
    25321 tgtaaccaag aaactgtcta ttggtgctat tgagcttatc aaggaatatc ttcctcgtgc
    25381 tgtagaaaat ggacatgata ttgaagcgcg tgaaggtatg gtcaatgcca tcttccttgg
    25441 tggtatgagc tttaataatg ctggtcttgg ctatgttcac tcaatggctc accaactcgg
    25501 tgcagtatat aatttgccac atggtgtttg ctgtgccatg ttgctaccag ttatagaacg
    25561 tgaaaatgct aaacgtgtac cagaagcttt ccgcaatgtt gccaaagcct tgggacttca
    25621 tgtagaaggt aaatcagatc aagaatgtgc cgattatgcg attgctgaga ttgagaagct
    25681 ttctgagaca gtaggtattc ctaagaaact gactgaactt ggtattgaag aaaaagattt
    25741 cgactttgaa tacctttcta agaatgcctt gattgatgcc tgcgcaccag gaaatccatt
    25801 tatgccaacc ttagaagaaa cgattgcctt ttataaagag ttattttagc aagagattgg
    25861 acgacaatag gacaattcac ctctaattat tgacatttca ggaaaaatcg cagtaaaaac
    25921 ggcacagcct tctttaaatg tgctataata ctagaaaaat acttgtggag gttccattat
    25981 ggcaatattt ttcatgattt ttctgattgt ttgtgtgctc ctattggtga tagtcacact
    26041 gagtacagtt tatgtggttc gtcagcagtc ggtggcgatt attgaacgct ttgggaaata
    26101 ccaaaaggtt gctaatagcg gtattcatat tcgcttgcct tttgggattg actcgattgc
    26161 agcacggatt cagttgcgct tgttgcaaag tgatattgtg gttgagacta agaccaagga
    26221 caatgtgttc gttatgatga atgtagcgac tcagtaccgt gtcaacgagc agagcgtgac
    26281 agatgcttac tataaactca tacgtccaga atctcagatt aaatcttata tcgaagatgc
    26341 tcttcgctct tctgttccaa aattaacctt ggatgaattg tttgagaaaa aagatgagat
    26401 tgcccttgaa gttcaacacc aagtagcaga agaaatgacc acttacggct acattatcgt
    26461 gaaaaccttg attaccaagg tcgaaccaga tgcagaagtt aagcaatcca tgaatgaaat
    26521 caatgcggcg caacgtaagc gggtcgcagc acaagaattg gcggaagctg acaagattaa
    26581 aattgtcact gcagctgaag cagaagcaga aaaagaccgc cttcatggtg tggggattgc
    26641 ccaacaacgt aaggcgattg tggatggatt ggcagagtct atcaccgaac tcaaggaagc
    26701 caatgttggc atgacagaag aacaaatcat gtctatcctc ttgaccaacc agtatttgga
    26761 taccttgaat acctttgcct ctaaaggaaa tcaaaccatc tttttaccaa atactccaaa
    26821 tggtgtggat gatatccgaa cacaaatctt gtcagccctt cgcgctgaga agaaataata
    26881 gactaatact cttcgaaaat ctcttcaaac cacgtcagcg tcgccttgcc gtatatttga
    26941 gctgacttcg tcagttctat ctgcaacctc aaaacagtgt tttgagctga cttcgtcagt
    27001 cttatctact acctcaaaac ggtgttttga gcaacctgtg gctagtttcc tagtttgcta
    27061 tttgattttc attgagtaca aagagcttgg caacaggctc tttttgtatt gcgtttatta
    27121 agaaaaacaa aaaacataga tatacattta actaaaaatt attgtatgtt acctccctta
    27181 attaggaatg ataagggaat aactagaaag atttgtgaat acaaactatt tctgatatac
    27241 aaaatataca gtaataatga atgatgggag atgggatgaa agaatttcaa tttgagagaa
    27301 agcagcgttt ttctttgagg aaatatgcaa taggagcttg ttcggtcttg ctaggaacga
    27361 gtttattttt tgctggtatg ggtgatcagc ctgtacagga tacagaaacg agttcagcac
    27421 taatttcaag tcattatttg gatgagcagg atttatctga aaagctgaaa tctgagttgc
    27481 aatggtttga attagaaaac aagcttttga acttatggga gcattaggtt actatgaagg
    27541 atttgttcct tatgtttcaa atcaatacaa aaaccaagct gaagaagaag gcaaaccgct
    27601 atctgataaa tatattttcg aaaaaatctt aggaaaaaca tatgcagcct tcaaaaaaga
    27661 tcaaattaat gagcgtgtcg agaaattagg taagttaaaa cctattacaa taaattacaa
    27721 cggaaaatca gaagtaattg atagtaaaga aaaattacaa gagcttatga ataaagccgt
    27781 taaagacgaa gtggctcaaa tatagtaaaa tgaaataaga acaggacaaa tcgatcagga
    27841 cagtcaaatc gatttctaaa aatgttttag aagtagaggt gtactattct agtttcaaca
    27901 tactataaaa tcaggcaata ccacggctaa aaagtttgag tttatcgaaa taccagtgca
    27961 aaaactgaaa aaagcgattt ataaagctca tctcaaagat tcagat
//
LOCUS       DAVHTH010000026        26683 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.026, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000026 DAVHTH010000000
VERSION     DAVHTH010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 26683)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26683)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26683
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.026"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            complement(100..903)
                     /locus_tag="VVR63_001143"
     CDS             complement(100..903)
                     /locus_tag="VVR63_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEU6129167.1"
                     /translation="MKKLATLLLLSTVALAGCSSVQRSLRGDDYVDSSLAAEESSKVA
                     AQSAKELNDALTNENANFPQLSKEVAEDEAEVILHTSQGDIRIKLFPKLAPLAVENFL
                     THAKEGYYNGITFHRVIDGFMVQTGDPKGDGTGGQSIWHDKDKTKDKGTGFKNEITPY
                     LYNIRGALAMANTGQPNTNGSQFFINQNSTDTSSKLPTSKYPQKIIEAYKEGGNPSLD
                     GKHPVFGQVIDGMDVVDKIAKAEKDEKDKPTTAITIDSIEVVKDYDFKS"
     gene            complement(987..1208)
                     /locus_tag="VVR63_001144"
     CDS             complement(987..1208)
                     /locus_tag="VVR63_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6129168.1"
                     /translation="MSFYGLFYNGIAITPNTYLSAWFVNFIAALPLNFLIVEPIARFI
                     LSSFQKPFTGEEVEEVEDFQDDDEIPTII"
     gene            complement(1687..1896)
                     /locus_tag="VVR63_001145"
     CDS             complement(1687..1896)
                     /locus_tag="VVR63_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000953868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6129169.1"
                     /translation="MLSVNTILEKFYKEHQVKPFISPERELDTWLLSPKPVPKRNMDL
                     LVDDSLAGDIILLWRIQFGTFTTET"
     gene            2066..2338
                     /gene="rpsP"
                     /locus_tag="VVR63_001146"
     CDS             2066..2338
                     /gene="rpsP"
                     /locus_tag="VVR63_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HEU6129170.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRSPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLAWLANGAQPSDTVRNILSKEGVLKKFHDSKFSK"
     gene            2358..2597
                     /locus_tag="VVR63_001147"
     CDS             2358..2597
                     /locus_tag="VVR63_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HEU6129171.1"
                     /translation="MDTIENLIIAIVKPLISQPDALTIKIEDTPEFLEYHLNLDQSDV
                     GRVIGRKGRTISAIRTIVYSVPTEYKKVRIVIDEK"
     gene            2865..3069
                     /locus_tag="VVR63_001148"
                     /pseudo
     CDS             2865..3069
                     /locus_tag="VVR63_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256436.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
     gene            3173..3922
                     /locus_tag="VVR63_001149"
     CDS             3173..3922
                     /locus_tag="VVR63_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEU6129172.1"
                     /translation="MKRFEVSTEIGSLSVTYQKQKKVLVCLNGAGLLPSYENFSLILE
                     KPPPTIGYLTIDFPNTGRSPIHDQAGKNLDNLADAVYEVLEELGISEYILCAHSWSGI
                     LACKLLEKPIKRQTLVVIEPTTKKVMFADFSENPYPEMEEQMRLIDECGPELYFKNLT
                     QATFSPETNKKIWELMQEKGLELENQDPEFQISGEITEEDFENLSIESHVPVFIFCQT
                     YREKEYRESEYWTSNTKLILGRNHHYLQWSE"
     gene            3992..4510
                     /gene="rimM"
                     /locus_tag="VVR63_001150"
     CDS             3992..4510
                     /gene="rimM"
                     /locus_tag="VVR63_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HEU6129173.1"
                     /translation="MNYFNVGKIVNTQGLQGEMRVLSVTDFAEERFKKGAELALFDEK
                     DQFVQTVTIASHRKQKNFDIIKFKDMYHINTIEKYKGYSLKVAEEDLNDLDDGEFYYH
                     EIIGLEVYEGDSLVGTIKEILQPGANDVWVVKRKGKRDLLLPYIPPVVLNVDIPNKRV
                     DVEILEGLDDED"
     gene            4500..5219
                     /gene="trmD"
                     /locus_tag="VVR63_001151"
     CDS             4500..5219
                     /gene="trmD"
                     /locus_tag="VVR63_001151"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HEU6129174.1"
                     /translation="MKIDILTLFPEMFSPLEHSIVGKAREKGLLDIQYHNFRENAEKA
                     RHVDDEPYGGGQGMLLRAQPIFDSFDAIEKKNPRVILLDPAGKQFDQAYAEDLAQEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDYVLTGGELAAMTMIDATVRLIPEVIGKESSH
                     QDDSFSSGLLEYPQYTRPYDYRGMVVPDVLMSGHHEKIRQWRLYESLKKTYERRPDLL
                     EHYQLTVEEEKMLAEIKENKE"
     gene            5231..5569
                     /locus_tag="VVR63_001152"
     CDS             5231..5569
                     /locus_tag="VVR63_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6129175.1"
                     /translation="MQVIKRNGEIAEFNPDKIYQAILKAAQTVYVLTDDLRQNLAQVT
                     KKVVLDLQEAKVERATISMIQSMVEHRLLGAGYITIAEHYISYRLQRDLERSGYGDHI
                     AVHLHFEQIR"
     gene            complement(5600..5920)
                     /locus_tag="VVR63_001153"
     CDS             complement(5600..5920)
                     /locus_tag="VVR63_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001216095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6129176.1"
                     /translation="MRHKFQQVLDKIHDFLNGHDQPDQTETNSLTATIEEAIQKQTAV
                     HLILSETSFTGDIIKYDQQGQQIIVKNFAKNVSRIIRISDIQRLRFVPSTVQTAQKNR
                     FKKE"
     gene            6018..6233
                     /locus_tag="VVR63_001154"
     CDS             6018..6233
                     /locus_tag="VVR63_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000807422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HEU6129177.1"
                     /translation="MAEFTFEIEEHLLTLSENEKGWTKEINRVSFNGAPAKFDIRAWS
                     PDHTKMGKGITLSNEEFQTMVDAFKGN"
     gene            complement(6302..6382)
                     /locus_tag="VVR63_001155"
                     /pseudo
     CDS             complement(6302..6382)
                     /locus_tag="VVR63_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(6438..6974)
                     /locus_tag="VVR63_001156"
     CDS             complement(6438..6974)
                     /locus_tag="VVR63_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000709035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HEU6129178.1"
                     /translation="MKKAHVYAIPAIGAALIAVLAQISLPIGPVPFTLQNFAIGLIAT
                     VFRPREAVLSAGLYLLLGAIGLPVFAGGGAGFQALVGPTAGYLWFYLVYSGLTSSLTN
                     SKSGVVKIFLANLLGDALVFVGGILSLHFLAGMAFEKALVVGVLPFIIPDLGKLLAIS
                     FISRPLLQRLKNQAYFTN"
     gene            7400..7738
                     /locus_tag="VVR63_001157"
     CDS             7400..7738
                     /locus_tag="VVR63_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6129179.1"
                     /translation="MKKRINKKASVFLVASVFSFSFATTASVVNAVTAHPAPSPIIDV
                     WEYGVNDNYGYSNYFVSSPSNIGSKSSVTNFWGTVKAQDKKDYGWAYSSATKSWNDVR
                     LNAYWDYYRF"
     gene            7804..9786
                     /locus_tag="VVR63_001158"
     CDS             7804..9786
                     /locus_tag="VVR63_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6129180.1"
                     /translation="MKLKLCIIGFFFCLIATIGLVTISDTEIPIPLPIDGAFSIQGKS
                     NLSNNEIYEMVRDLSKTEKVTIYKPIVQSSGQLKYVNFDDVNNEQLKSAPIVGMYYTL
                     GKMDVDSLKPLTMTGLQTVYMAYPWYIGGILQFTGTLRILLMGSIYLTLLVVLFVVRT
                     RQIKEGVIRRSLGLPIYDLRREYGISLIFELIMMALLMISYSSFLGNGFFTYSSKLFF
                     SLLLTNFILFQIIDLITFVLFWLTIQIEKPIEIIKNKAKNKLIFVVWLAIISIIILVS
                     GVFLQETKSSQSSINIQIQNLVPWDTVKDWRRIEFLGIESNSTKNREVNDSDGQYLQI
                     VAALKNLDFLYIERSSAYVPDFMKTSHVIENFSKQLENDGITNPEINKELIYINQTGA
                     NLQNKVNGTNYHLLDNKIATIYIPEKWKENQKSIENTVVAEQFIGTNYTREQLAVQII
                     PDGEKIFYFNEDADNNLKMKDILPLANVADSKDNIVVVLDTDKMMENNKFSLASNILY
                     KSLFSPEAVKKINEMTVLLNFSMNPVDVYQIVKLKIQSLEHQILLSQILQKIIYSIVF
                     ILIYQYVQLFITLKQNEYVKKIILGLSKTYIAISSLKYFMMTITMVILFTFLMTGQIE
                     LLYIGAASLLVLMLSIIMSFRKLSESYTKILKGDES"
     gene            9783..10406
                     /locus_tag="VVR63_001159"
     CDS             9783..10406
                     /locus_tag="VVR63_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU6129181.1"
                     /translation="MTIDLLNVSKSFGSKKIFTDLNLIFESGKSYALIGGSGSGKSTL
                     LNIIGRLEKIDSGNVLVDKQDIWKIKERTFFKNTVGYVFQNYSLIDNKTVYDNLSLIT
                     KDKKTITDVLEKVGLSSDYLHQKIYELSGGQAQRVAIARMLMKPRKIILADEPTGALD
                     GEIGKEIIRLLLNETAEDKYVIIATHDPAVYNEVDVIIDMKDIGYKV"
     gene            10403..10903
                     /locus_tag="VVR63_001160"
     CDS             10403..10903
                     /locus_tag="VVR63_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6129182.1"
                     /translation="MKKKIYIALIFVTGVLAIFFFGKQMITKENINKPTVELTIYTLS
                     SSDTEKWNKVRQVETEEAIYFITVKEVSSSEEVFSNIIANGAATGFGVREEEVKKFNN
                     GLGDTIEDSKHNKLIEIEFFTFSDDGAGFVVANFDYGKEELNSQKKDIKELYKKIYES
                     FKEKNK"
     gene            complement(11069..12415)
                     /gene="gor"
                     /locus_tag="VVR63_001161"
     CDS             complement(11069..12415)
                     /gene="gor"
                     /locus_tag="VVR63_001161"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HEU6129183.1"
                     /translation="MREYDIIAIGGGSGGIATMNRAGEHGAKAAVIEEKKLGGTCVNV
                     GCVPKKIMWYGAQIAETFHQFGEDYGFKTTDLNFDFATLRRNREAYIDRARSSYDGSF
                     KRNGVDLIEGHAEFVDSHTVSVNGELIRAKHIVIATGAHPSIPNIPGAELGGSSDDVF
                     AWEELPESIAILGAGYIAVELAGVLHTFGVKTDLFVRRDRPLRGFDSYIVEGLVKEME
                     RTNLPLHTHKVPVKLEKTTDGITIHFEDGTSHTASQVIWATGRRPNVKGLQLEKAGVT
                     LNERGFIQVDEYQNTVVEGIYALGDVTGEKELTPVAIKAGRTLSERLFNGKTTAKMDY
                     STIPTVVFSHPAIGTVGLTEEQAIKEYGQDQIKVYKSSFASMYSACTRNRQESRFKLI
                     TAGSEEKVVGLHGIGYGVDEMIQGFAVAIKMGATKADFDATVAIHPTASEEFVTMR"
     gene            12680..13879
                     /locus_tag="VVR63_001162"
     CDS             12680..13879
                     /locus_tag="VVR63_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HEU6129184.1"
                     /translation="MKKKNGKAKKWQLYAAIGAASVVVLGAGGILLFRQPSQTALKDE
                     PTHLVVAKEGSVASSVLLSGTVTAKNEQYVYFDASKGDLDEILVSVGDKVSEGQALVK
                     YSSSEAQAAYDSASRAVAKADRHINELNQARNEAASAPAPQLPAPVGGEDATVQSPTP
                     VAGNSVASIDAQLGDARDARADAAAQLSKAQSQLDATTVLSTLEGTVVEVNSNVSKSP
                     TGASQVMVHIVSNENLQVKGELSEYNLANLSVGQEVSFTSKVYPDKKWTGKLSYISDY
                     PKNNGEAASPAAGNNTGSKYPYTIDVTGEVGDLKQGFSVNIEVKSKTKAILVPVSSLV
                     MDDSKNYVWIVDEQQKAKKVEVSLGNADAENQEITSGLTNGAKVISNPTSSLEEGKEV
                     KADEATN"
     gene            13863..14564
                     /locus_tag="VVR63_001163"
     CDS             13863..14564
                     /locus_tag="VVR63_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6129185.1"
                     /translation="MKQLISLKNIFRSYRNGDQELQVLKNINLEVNEGEFVAIMGPSG
                     SGKSTLMNTIGMLDTPTSGEYYLEGQEVAGLGEKQLAKVRNQQIGFVFQQFFLLSKLN
                     ALQNVELPLIYAGVSSSKRRKLAEEYLDKVELTERSHHLPSELSGGQKQRVAIARALV
                     NNPSIILADEPTGALDTKTGNQIMQLLVDLNKEGKTIIMVTHEPEIAAYAKRQIVIRD
                     GVISSDSAQLGKEEN"
     gene            14566..15825
                     /locus_tag="VVR63_001164"
     CDS             14566..15825
                     /locus_tag="VVR63_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6129186.1"
                     /translation="MQNLKFAFSSIMAHKMRSLLTMIGIIIGVSSVVVIMALGDSLSR
                     QVNKDMTKSQKNISVFFSPKKSKDGSFTQKQSSFTVSGKEEEIPVEPPKPQESWVQEA
                     AKLKGVDSYYVTNSTNAILTYQDKKVENANLTGGNRTYMDAVKNEIIAGRSLREQDFK
                     EFASVILLDEELSISLFESPQEAINKVVEVNGFSYRVIGVYTSPEAKRSKIYGFGGLP
                     ITTNISLAANFNIDEIASIVFRVNDTSLTPTLGPELARKMTELAGLQQGEYQVADESV
                     VFAEIQQSFSFMTTIISSIAGISLFVGGTGVMNIMLVSVTERTREIGLRKALGATRAN
                     ILIQFLIESMILTLLGGLIGLTIASGLTALAGLLLQGLIEGIEVGVSIPVALFSLAVS
                     ASVGMIFGVLPANKASKLDPIEALRYE"
     gene            15949..17946
                     /gene="metG"
                     /locus_tag="VVR63_001165"
     CDS             15949..17946
                     /gene="metG"
                     /locus_tag="VVR63_001165"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HEU6129187.1"
                     /translation="MSEKNFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGYDV
                     FYLTGLDEHGQKIQQKAEEAGITPQAYVDGMAVGVKELWQLLDISYDKFIRTTDDYHE
                     KVVAQVFERLLAQDDIYLGEYSGWYSVSDEEFFTESQLAEVFRDEAGNVTGGIAPSGH
                     EVEWVSEESYFLRLSKYQDRLVEFFKAHPEFITPDGRLNEMLRNFIEPGLEDLAVSRT
                     TFTWGVPVPSNPKHVVYVWIDALLNYATALGYAQDEHGNFDKFWNGTVFHMVGKDILR
                     FHSIYWPILLMMLDVKLPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERYGLDPLRY
                     YLMRNLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVSMINKYFDGQIPAYVEGVT
                     EFDHVLAEVAEQSIADFHTHMEAVDYPRALEAVWTLISRTNKYIDETAPWVLAKDEAL
                     RDQLASVMSHLAASIRVVAHLIEPFMMETSRAVLTQLGLEEVSSLENLSLADFPADVT
                     VVAKGTPIFPRLNMEEEIAYIKEQMEGNKPAVEKEWNPDEVELKLNKDEIKFEDFDKV
                     EIRVAEVKEVSKVEGSDKLLQFRLDAGDGEDRQILSGIAKYYPNEQELVGKKVQIIAN
                     LKPRKMMKKYVSQGMILSAEHDGKLTLLTVDPAVPNGSVIG"
     gene            18277..18597
                     /locus_tag="VVR63_001166"
     CDS             18277..18597
                     /locus_tag="VVR63_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEU6129188.1"
                     /translation="MKETQLLKGVLEGCVLDMIGQKERYGYELVQTLREAGFDTIVPG
                     TIYPLLQKLEKNQWIRGDMRPSPDGPDRKYFSLMKEGEERVSVFWQQWDDLSQKVEGI
                     KNGG"
     gene            18601..19416
                     /locus_tag="VVR63_001167"
     CDS             18601..19416
                     /locus_tag="VVR63_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6129189.1"
                     /translation="MKKMKYYEETSALLHEFSEENQKYFEELWESFNLAGFLYDEDYL
                     REQIYLMMLDFSEAERDGMSAEDYLGKNPKKIMKEILKGAPRSSIKESLLTPILVLAV
                     LRYYQLLSDFSKGPLLTVNLLTFLGQLLIFLIGFGLVATILRRSLVQDSPKMKIGTYI
                     VVGTIVLLVVLGYVGMASFIQEGVFYIPAPWDSLSVFTISLVIGIWNWKEAVFRPFVS
                     MIIAHLVVGSLLRYYEWMGISNVFLTKVIPLAVLFIGIFVLFRGFKKIKWSEV"
     gene            19491..20417
                     /locus_tag="VVR63_001168"
     CDS             19491..20417
                     /locus_tag="VVR63_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HEU6129190.1"
                     /translation="MRYITLGQDDKELSEIVLGMMRIKDKSVKEVEELVETALSVGIN
                     AFDLADIYGRGRCEELLGLVLKNRPDLREKMWIQSKCGIRIEEFTYFDFSKDYIIKSV
                     DGILQRLKINHLDSLLLHRPDALMESDQVAEAFDLLYKQGKVRDFGVSNQNPMMMELL
                     KKDVKQPLAVNQLQLSAAFTPGFESAFHVNMEDSQAAMRDGSIFEYCQLHDVVIQAWS
                     VLQFGYFKGNFVGNEKFQALNQVLDRLAIKYGVTSSTIAISWILRYPAKMQAVVGTTN
                     PKHLREVSRAANFSLTRKEWYEIYLAAGNNLP"
     gene            20483..20749
                     /locus_tag="VVR63_001169"
     CDS             20483..20749
                     /locus_tag="VVR63_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HEU6129191.1"
                     /translation="MKNVELKEKNMTFEEILPGLKAKRKYVRTGWGGAENYVQLFDTI
                     EQNGLALEMTPYFLINVSGEGEGFSMWSPTVCDVLATDWVEVHD"
     gene            20742..21440
                     /locus_tag="VVR63_001170"
     CDS             20742..21440
                     /locus_tag="VVR63_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HEU6129192.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLEKGYQVYGVDQGEKPLLEGDF
                     HFLQRDLTLDLEPIFDWCPQVDVLCNTAGVLDAYKPLLEQTAQDIQEIFEINYIIPVE
                     LTRYYLTQMLENKKGIIINMCSIASSLAGGGGHAYTSSKHALAGFTKQLALDYAEAGI
                     QVFGIAPGAVKTAMTAADFEPGGLADWVASETPIKRWIEPEEIAELSLFLASGKASAM
                     QGQILTIDGGWSLK"
     gene            21451..21930
                     /locus_tag="VVR63_001171"
     CDS             21451..21930
                     /locus_tag="VVR63_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU6129193.1"
                     /translation="MEIKKHFGVYAVCLENGKLLCIEKTRGPYQHRYDLPGGSQQLGE
                     GLTETLTREVMEETGFTVRSYSNPRIYDVFVREELKNFMVHHVMALYDVEMNESAPQV
                     TTSEAVSDGANDSLGYIWMDIQEITEENASPLVLKVKSELLGFPELDKTSYMNWKVK"
     gene            21938..22666
                     /locus_tag="VVR63_001172"
     CDS             21938..22666
                     /locus_tag="VVR63_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6129194.1"
                     /translation="MELFKTWKKNMVLYGLKSQIGTVYRNNDRTTSFYDVGNFLYLAG
                     ELDSRFWEDFVRKYGLDYKIIISENTNWQDFLHRKVGLNSFTRYSFKDKANFQVEFLN
                     NLVTHLEEGYNIVPIDNHIYNCFSTEEWSQDLQGDFESYQDFVLKGGFGFVILKNNEL
                     IAGISSGLVYRKAVEVEVATRPNEQGNGFAKKLGAAMILESLNRDMFPLWDAHNEASK
                     KVAEFLGYELSEPYEAFELEEILI"
     gene            22708..23577
                     /locus_tag="VVR63_001173"
     CDS             22708..23577
                     /locus_tag="VVR63_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PEP-utilizing enzyme, TIM barrel domain protein"
                     /protein_id="HEU6129195.1"
                     /translation="MRNQLALSGEKILEKIYPQLFHHVGMIRGEYLLRELNQNIILAS
                     CQQFVKDYLETICSLYSDEEVWYRFTELTNTEANCLVGTKEFFDEGHPLFGYRGTRRL
                     LACLDEFQAEAHVVTEVYQTNSNLSVIFPFVNDADQLKQAITVLRQYGFTGKVGTMIE
                     LPSAYFDLSSILETGISKIVVGMNDLTSFVFATMRNSQWHDMESPIMLDMLRDMQDKA
                     RKNKINFAVAGYLNTSFIQKMNQLGIKCIIHYSSIPEIFDLEIDHPDHLKHIKEESKK
                     LQRSTHDTARNVE"
     gene            23552..23992
                     /locus_tag="VVR63_001174"
     CDS             23552..23992
                     /locus_tag="VVR63_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HEU6129196.1"
                     /translation="MIPQEMWNKYKQINPLIGDEIDAWAFGVEPDLLADLVFKGEKTA
                     TASAYDLYVLEDEPLPQVGTFDIILDSQNQSVCIVEITKVSVELFNQVSAQHAFKEGE
                     GDKSLAYWRQVHEDFFTNCLGEVGLTFTPESKVVLEEFRKVYPL"
     gene            24115..26661
                     /locus_tag="VVR63_001175"
     CDS             24115..26661
                     /locus_tag="VVR63_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001149089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HEU6129197.1"
                     /translation="MQAVEHFIKQFVPEHYDLFLDLSRETKTFSGKVTITGQAQSDRI
                     SLHQKDLEITSVEVAGQARPFTVDHDNEALHIELAEAGQVELVLAFSGKITDNMTGIY
                     PSYYTVDGVKKEVLSTQFESHFAREAFPCVDEPEAKATFDLSLRFDQAEGELALSNMP
                     EIDVENRKETGIWKFETTPRMSSYLLAFVAGDLQGVTAKTKNGTLVGVYSTKAHPLSN
                     LDFSLDIAVRSIEFYEDYYGVKYPIPQSLHIALPDFSAGAMENWGLVTYREVYLVVDE
                     NSTFASRQQVALVVAHELAHQWFGNLVTMKWWDDLWLNESFANMMEYVCVDTIEPSWN
                     IFEDFQTGGVPLALERDATDGVQSVHVEVKHPDEINTLFDGAIVYAKGSRLMHMLRRW
                     LGDADFAKGLHAYFEKHQYSNTIGSDLWDALGQASGRDVAAFMDSWLEQPGYPVLTVK
                     VENDVLKISQKQFFIGENEDKNRLWVVPLNSNWKGLPDTLETESIEIPGYAALLAENE
                     GALRLNTENTAHYITDYQGDLLEAVLAELETLDNTSKLQIVQERRLLAEAGHISYADL
                     LPVLDKLAKEESYLVVSAVSQVISALERFIDEGTDAETAFKGLVAKLARHNYDRLGFE
                     AKDGESDEDELVRQLAVSMMIRSNDAEARQVASQIFATHKENLAELPAAIRSQVLINE
                     MKHHETKDLLALYLDTYTHATDAVFKRQLAAALAYSTDADNIQNLITSWKDKFVVKPQ
                     DLSAWYYQFLAHQATQKTAWSWARENWAWIKAALGGDMSFDSFVILPAHVFKTQQRLA
                     EYKEFFEPQLSDLALSRNIGMGIKEIAARVDLISREKAAVEAVVLQYGNA"
BASE COUNT         8434 a         4543 c         5696 g         8010 t
ORIGIN      
        1 taaaataggc tccataatat ctatagtgga tttacccact atagatatta tagagccaga
       61 aatacagtac cgaatgtgga tactgtattt ttttggtttt taagatttaa aatcgtagtc
      121 tttcaccact tcgatgctgt cgattgtgat agcagtagtt ggcttgtctt tttcatcttt
      181 ttcggcttta gcaatcttat ccacaacatc cataccgtca atcacttgac caaagactgg
      241 gtgtttgcca tctagactag ggtttccacc ttctttgtag gcttcgataa ttttctgtgg
      301 atacttgctt gtagggagtt tagaagaggt atctgtagag ttttggttga tgaagaactg
      361 gctgccattg gtgtttggtt gaccagtatt agccatagca agagcaccac ggatgttata
      421 caaataagga gtaatctcgt tcttgaaacc agttcctttg tctttagtct tatccttgtc
      481 atgccatatg gactgaccac ctgtaccgtc cccttttgga tctccagttt ggaccataaa
      541 gccatcgatg acacggtgga aggtaatacc gttatagtag ccttctttgg cgtgagtgag
      601 gaaattttca accgctagag gagcgagttt agggaagagt ttaatgcgaa tatcaccttg
      661 gcttgtgtgg agaatcactt cggcttcatc ttcagcaact tccttagata gttgtgggaa
      721 attggcgttt tcgtttgtta aagcatcgtt taactccttg gcagattggg cagctacttt
      781 ggaactttct tcagcagcaa gactggaatc aacataatca tcaccacgca gactgcgttg
      841 gacgctgcta cacccagcta gggctacagt agacagtaaa agaagggttg ctagtttttt
      901 cattctgatc ctctcaaaaa ttcatttata accattgtac cctaaaagga agtggatttc
      961 aaatattagt agtttacaga actggcttag ataatagttg ggatttcatc atcatcttga
     1021 aaatcttcaa cttcttcaac ttcttcccca gtaaatggtt tctgaaaaga acttagtata
     1081 aaacgggcaa ttggttcaac aattaggaaa tttagaggaa gagctgcaat aaagtttacg
     1141 aaccaggcgc ttagataggt attgggtgtg atagcaatgc cattgtaaaa aagtccatag
     1201 aaggacatga aagtgaccag ctaattcttc ttctgaaaaa tgctcatgaa gggcttgatc
     1261 caggtcgcaa gatttcattt tagaaagtcc agtaactccc ttcttcttca ggatattctt
     1321 tttcatggta gtatttagat ggtcaagtga gtcaaaagaa gtttcgacaa gagcataccc
     1381 tttttctacc agagttttta gatgtttagg ggcatcaata ccataagtgt actcaaagta
     1441 ttttggaaac cagatcttaa gaaagctcgt aaagctagcc agttctctaa acgctaagaa
     1501 ctagctacaa cacagcattt acaacacttc atggttcaca ccatggggtg ttttttaatg
     1561 attttaagca aaattcacac ttaattgaaa gttatttaaa ttagatgaaa atttattttt
     1621 tgaaaaagtg ggaaaacatt gattctaagc gaattttgaa tcatattcga atgggagttt
     1681 ttaaaatcat gtttcagtgg taaaagtacc aaactggatt ctccatagta aaatgatatc
     1741 tcctgctagt gaatcatcta ctaataagtc catatttcgc ttgggaacgg gcttgggact
     1801 tagaagccaa gtatccaact ctcgttcagg cgatatgaag ggtttgactt ggtgttcttt
     1861 ataaaatttt tctaaaatag tattcacgga tagcatcttt caaacattta tttcctattc
     1921 taacaaattt ctaaatactt taagaaattt atagtctgtc aagttttttt cttgacacat
     1981 gccagaaatc tgctataata gaacatgtgc tagatagctc agctatttca ccgaaataaa
     2041 aaattaaaga aatgagactt taaaaatggc agttaaaatc cgtttgactc gtatgggttc
     2101 taagaaaaaa cctttctacc gtatcaacgt agcagattca cgttcaccac gtgacggacg
     2161 tttcatcgaa acagttggaa cttacaaccc acttgttgct gaaaaccaag taactttgaa
     2221 agaagaccgc gttcttgcat ggttggctaa tggagctcaa ccttcagaca cagtacgtaa
     2281 catcctttca aaagaaggcg tattgaaaaa attccacgat tctaaatttt caaaataagt
     2341 ttaaagtagg ttgacagatg gatacgattg aaaatctcat tattgcgatt gtgaaaccct
     2401 taatttcaca accagatgcc ttaactatca agattgagga tacaccagaa tttttggaat
     2461 atcatttgaa tcttgatcaa agcgatgtgg gtcgtgtaat cggtcgtaag ggtcgcacta
     2521 tttctgcgat aagaacgatt gtctactctg tcccaactga atacaaaaaa gtaagaatcg
     2581 ttattgacga aaaataagaa gggcgggacg gatgtctcgc ttttttgtgt ggaatagaag
     2641 atatagtaaa atgaaataat aacaggacaa atcgatcagg acagtcaaat cgatttctaa
     2701 caatgtttta gaagtaaagg tgtactattc tagtttcaat atactataaa agattgaacg
     2761 tttaggcaat tccaagacta cttactcgaa cattaacagc agtctcggac tgatgaaggt
     2821 ctctttatga agttagtgga gaagtcggag aagtagccga ggttttgaat aggcgctctg
     2881 gtcgaaaaga agggatagga ttcgaacgag gaacttgcca gagaactggc tgatatcatt
     2941 tactacaccg tcgcaatcgt agctattaat catattgacc ttaccaagac tgtctttgag
     3001 aaagacaaaa ccgcagccgt taattaccaa cataaacatg atttggaagg atttttgaag
     3061 ggaaagtaga gatgttgtcc ccttcctcca acttgagaaa atccttggaa cgtgataaaa
     3121 taaaagataa ggatttttaa taattcatta tatagaatga gtggatttct ttatgaagag
     3181 gtttgaagta tctacagaaa ttggtagcct ctctgttact tatcaaaagc aaaagaaagt
     3241 gctagtttgt ctaaacggag caggtttgct accaagttat gaaaattttt cacttatact
     3301 tgaaaaacct cctcctacaa ttggttattt gacaattgat tttccgaaca caggtaggag
     3361 tccgattcat gaccaagctg gaaaaaatct agataatctt gcagatgcgg tttatgaagt
     3421 acttgaagaa ttaggaattt ctgaatatat actttgtgca catagttgga gtggaatttt
     3481 agcttgcaaa ttactcgaga aaccaattaa gcgtcagact ttagtagtaa ttgaaccgac
     3541 aactaaaaaa gtcatgtttg ctgatttttc agaaaatcct tatccagaaa tggaagagca
     3601 gatgaggctg attgacgagt gtggtcctga actttatttt aagaacttaa ctcaagcaac
     3661 atttagtcct gaaacgaata aaaaaatctg ggaattaatg caagaaaaag gcttagagtt
     3721 ggaaaatcaa gatccagaat ttcagatatc tggagagatt actgaggaag attttgagaa
     3781 tttgtcgata gaatctcatg tccctgtatt tattttttgt cagacttata gagaaaaaga
     3841 gtacagagaa tcagaatatt ggacttccaa tactaaactc attttaggaa ggaatcacca
     3901 ttatttacaa tggtcagaat aggaaaaaat tgcggctatt attcgagaat tgtcagaata
     3961 agatggaaaa aaggagatta caggagacaa gatgaactac tttaatgttg ggaaaatcgt
     4021 taatacgcag ggattacagg gtgagatgcg agtcttgtct gtgacggatt ttgcagaaga
     4081 acggtttaaa aaaggagctg agctggcttt gtttgatgaa aaagatcagt ttgtccaaac
     4141 agtgaccatc gctagccacc gtaaacagaa gaactttgac attattaaat tcaaagatat
     4201 gtaccatatc aatactatcg aaaagtacaa gggatacagt ctcaaggtcg ctgaggaaga
     4261 tttgaatgac ctagacgatg gtgaatttta ctatcacgag attatcggtt tggaagtcta
     4321 tgagggtgat agcttggttg gaaccatcaa ggaaatcctg caaccaggtg ctaatgatgt
     4381 ctgggtggtc aaacgaaaag gcaaacgtga tttgctttta ccttatatcc caccagtggt
     4441 tctcaatgtt gatattccaa ataaacgggt cgatgtggaa atcttagaag ggttagacga
     4501 tgaagattga tattttaacc ctctttccag agatgttttc tccactggag cactcaatcg
     4561 ttggaaaggc tcgagaaaaa gggctcttgg atatccagta tcataatttt cgagaaaatg
     4621 ctgaaaaggc ccgtcatgta gatgatgagc cctacggagg cggtcagggc atgttgctca
     4681 gagcacaacc tattttcgat tcctttgatg ctattgaaaa gaaaaatccg cgcgttattc
     4741 tcctcgatcc tgctggaaag cagtttgatc aggcttatgc tgaagatttg gctcaagagg
     4801 aagagctaat ctttatctgt gggcactatg agggttatga tgagcgcatt aagaccttgg
     4861 taacagatga gatttcccta ggcgactatg tcctcactgg tggagaattg gcagctatga
     4921 ccatgattga tgctacagtt cgcctgattc cagaagtgat tggcaaggag tctagccacc
     4981 aagatgatag tttttcttca ggtcttttag aatatcctca gtacacacgt ccctatgatt
     5041 atcgaggcat ggtcgtgcca gatgtattga tgagtggcca ccatgaaaag attcgtcagt
     5101 ggcgattgta cgagagttta aagaaaacct acgagcgcag accggattta cttgaacatt
     5161 atcaactgac agtagaagaa gaaaaaatgc tggcagaaat caaagaaaac aaagaataaa
     5221 ggagaaacct atgcaagtaa tcaaacgtaa tggcgaaatt gctgaattta atccagataa
     5281 gatttaccaa gccatcttga aggcagccca aactgtttat gttttgacag atgatttgcg
     5341 tcaaaatctt gctcaagtca ctaagaaggt agttttggat ttacaagaag ccaaggtgga
     5401 acgtgcgact atcagtatga ttcaatctat ggttgaacat cgtttattgg gcgcaggtta
     5461 cattaccatt gcagaacact acatttccta tcgtttacaa cgtgacttgg aaagaagtgg
     5521 ttatggagat catattgcag ttcatttaca ttttgaacaa attcgctaag aaaaaagagt
     5581 gggatgaagc aactacatct cactctttct taaatctatt tttttgggct gtttggacag
     5641 ttgaggggac aaatcgcagg cgttgaatat cgcttatacg gataatccgg ctcacatttt
     5701 tggcaaaatt tttcacgata atttgctggc cttgctgatc atatttgatg atatcacctg
     5761 taaaacttgt ctcagacaag ataaggtgaa cagcggtttg tttctggata gcctcttcaa
     5821 tagtggctgt aagggagttg gtttcagtct ggtcaggttg gtcatgtcca tttaaaaaat
     5881 catgtatttt atctagaact tgctggaatt tatgtctcat attggcctcc cttcttttat
     5941 atcaatatta tataaaattt tcctaaaatc tacaagattt tacgaataaa ctaatgaaac
     6001 taaaaaagga gaagaaaata gcagaattta catttgaaat cgaagagcac ttgttgactc
     6061 tttctgaaaa cgaaaaaggt tggaccaagg aaattaaccg tgtgagcttt aatggtgccc
     6121 ctgcaaagtt tgatattcgt gcttggagtc cagaccatac taaaatgggc aaagggatta
     6181 ctctctcaaa tgaagaattt caaacgatgg tggatgcctt taaaggcaac taatactctt
     6241 cgaaaatctc ttcaaaccgc atcagctttg ccttgccgta tgtatggtta ctgacttcgt
     6301 cagtttcatc cacaacctca aaacagtgtt ttgagcagcc tgcggctagc ttcctagttt
     6361 gctctttgat tttcattgag tataagtttt caaaataaaa aaaaggatat tgagtcatga
     6421 taactcggta tcctttttta gttagtaaag taagcctgat ttttaaggcg ttgaagtagg
     6481 ggacggctaa taaaactaat agccagaagt ttgccaaggt ctggaatgat aaagggaaga
     6541 acccccacaa caagagcttt ttcaaatgcc attccagcta ggaaatgcaa gctgagaatc
     6601 ccgccgacaa agacaagggc atcacccaag aggtttgcaa gaaaaatctt aacaacacca
     6661 ctcttgctgt tggttagaga ggaagtaagt ccagagtaaa cgagataaaa ccaaagatag
     6721 cctgcagtag ggccaactaa agcctgaaaa ccagctccac ctcctgcaaa gacaggaaga
     6781 ccgatagcac ctagaagaag atagagtcca gcagaaagta cagcctctct cggtctaaag
     6841 acagtagcaa tcaagccgat tgcaaagttt tgcagagtga agggaacagg tccaattgga
     6901 agactgattt gtgccaaaac agcaatgaga gcagccccaa tagcagggat agcataaacg
     6961 tgagcttttt tcaaaatagt taacctcttt tctaatgtat agtaactatt atactcatat
     7021 aggagtcgat gtcaaccatt ttttaaaaac aaggtaacaa aaactgtaac agccgatttt
     7081 cgtgactagt caagttggat aatttttttg ttgattcgaa aattgtctgt atagataatc
     7141 ctattttatt aataaaaaat atactagtaa atacttgaca aattaaaaaa taagtgttac
     7201 attaaaaatg taaacggata catttagatg tgttcaattt taaaaggagg ggtagttatg
     7261 agatatttta acgactctag ataccataac ggtgattaaa aacctaaata taatcaattc
     7321 atattaaagt aatatggagg gactaaaaag agactattat ttaatcttca tcaaatattt
     7381 aaattcaagg agaagtaaaa tgaaaaaaag aattaataag aaagcatctg tttttctagt
     7441 tgcaagtgtt ttcagtttta gctttgctac tacagctagt gtcgttaacg cagtaacggc
     7501 acaccctgct ccaagtccca ttattgatgt atgggaatat ggtgtaaatg ataactatgg
     7561 ttattcgaat tactttgtta gttctccaag taatattgga tcaaaatctt cagtaacgaa
     7621 tttttgggga acagttaaag ctcaggataa aaaagattat ggatgggcat attcaagtgc
     7681 aacaaaatct tggaacgatg ttcgcttaaa tgcatattgg gattattata gattttaaaa
     7741 ataatttatg aaaacaagag acccaattat aagattgggt ctcttgtaat atggtaattg
     7801 cttatgaaat taaaattatg tatcattgga ttcttctttt gtttgattgc tacaattggt
     7861 ctggtcacta ttagtgatac cgaaatcccc atacctttac caattgatgg agctttttct
     7921 atccaaggaa aaagtaatct ttctaataac gaaatatacg aaatggttcg tgacttatca
     7981 aaaacggaaa aggttaccat ttacaagcca atcgttcaga gttcgggtca gttgaagtat
     8041 gtaaattttg atgatgtaaa taatgaacaa ttaaagtcag caccaatagt agggatgtat
     8101 tacacacttg ggaaaatgga tgtagacagt ttgaaaccac ttacgatgac gggactacaa
     8161 acagtctata tggcttatcc ttggtatata ggaggaatat tacaattcac tggaacttta
     8221 agaatactgt taatgggttc aatttattta actttattag ttgttttatt tgttgttagg
     8281 acgaggcaga tcaaagaagg agtgatacga cgttctttgg gcttgcctat atacgactta
     8341 agaagagagt atggcatttc tcttattttt gaactgatta tgatggcttt attgatgatt
     8401 tcttacagtt cttttttggg taatggtttc ttcacctata gttctaagtt atttttctct
     8461 ctgcttttaa cgaattttat actatttcaa atcattgatc ttattacttt tgttttattt
     8521 tggttgacga ttcagattga aaagcctatt gaaattatta aaaacaaggc aaaaaacaag
     8581 cttatttttg tcgtatggct tgctattatt tcgattatca tccttgtctc aggagttttt
     8641 ttacaagaaa caaagagtag tcaatctagt attaacatac agatacagaa tttagtacca
     8701 tgggatacag taaaagactg gagaaggatt gagttccttg gaattgaaag taactctact
     8761 aaaaatagag aagttaatga ttcagatggt cagtatctac agatagttgc tgccttaaaa
     8821 aacttagatt tcttatatat agaacggtct tcagcatatg ttccagattt catgaaaact
     8881 tcacatgtta tagaaaattt ttctaaacaa ttagaaaatg acgggataac gaatccagaa
     8941 ataaataaag agttaattta tatcaaccaa acaggtgcta acctacaaaa taaagtgaat
     9001 ggaacaaact atcatctttt agataataag atagcaacca tctatattcc tgagaagtgg
     9061 aaagaaaacc agaaatctat tgagaataca gttgtagcag aacaatttat tggaacaaac
     9121 tatacaagag aacagcttgc agttcaaata attcctgatg gggaaaaaat tttttatttt
     9181 aatgaggatg ctgataataa tcttaaaatg aaagatattt taccgctggc aaatgtagca
     9241 gatagcaaag ataatatagt tgttgtgtta gatacggaca aaatgatgga aaataataag
     9301 ttttctttgg ctagtaacat actatataaa tctcttttta gtcctgaagc ggtaaaaaaa
     9361 ataaatgaga tgactgtcct gttgaatttc tcaatgaatc cagtagatgt ttaccaaatt
     9421 gtgaaattaa agattcaatc cttagagcac caaattttac tttcacaaat cttgcagaag
     9481 ataatttaca gtattgtctt tatactcatt tatcaatatg tccaactttt tattactcta
     9541 aaacagaatg aatatgtgaa aaaaatcatt ttgggtctgt caaaaacata tatagcaatt
     9601 tcaagtctca aatattttat gatgactatt acaatggtta ttctatttac atttcttatg
     9661 acagggcaaa tagagttgct atatattgga gcggcttctc tgctagtttt gatgttgtca
     9721 atcataatga gttttagaaa attatctgaa agctacacta aaattttaaa aggagatgaa
     9781 tcatgacaat tgaccttttg aacgtttcaa aaagtttcgg ctcaaagaag atctttacag
     9841 acttaaattt aatatttgaa tctggaaaaa gctatgcatt gattggaggt tctggctccg
     9901 gtaaaagtac ccttcttaat attataggaa gattagaaaa aattgacagt gggaatgttt
     9961 tagttgataa acaagatatt tggaagataa aagaaagaac tttttttaaa aatactgttg
    10021 gatatgtatt tcagaattat tctttaatag ataacaaaac agtgtatgat aatctgagcc
    10081 ttatcactaa agacaaaaaa acaataactg acgtacttga aaaagtagga ctgtcaagtg
    10141 actatttaca ccaaaaaata tatgaattgt ctggagggca ggctcaacgt gtagctattg
    10201 ccagaatgtt aatgaaacca cgtaaaatta tcttagcaga tgaacctaca ggagctttag
    10261 atggtgagat tggaaaagaa attattcgtt tactattgaa tgaaacagct gaagataaat
    10321 atgtcattat agcgacacat gatccagctg tctataacga agttgatgtg ataattgaca
    10381 tgaaagatat agggtataag gtatgaaaaa gaaaatttat attgctttga tctttgtaac
    10441 tggggtactc gccattttct tttttggaaa acaaatgatt acaaaagaaa atatcaataa
    10501 gccaacggta gagttaacaa tctatacgct ttcttctagt gatacagaaa aatggaataa
    10561 agtgagacaa gtagaaacgg aagaagctat atacttcata actgtgaaag aagtatcatc
    10621 ttcagaagaa gtattttcaa acatcattgc aaatggagct gctacggggt tcggagttcg
    10681 tgaagaagaa gtgaagaaat tcaataatgg tttaggagac accatagagg actctaagca
    10741 taataaacta attgaaatag aattttttac tttttctgat gatggcgcgg gatttgtggt
    10801 agcaaacttt gactacggta aagaagagtt gaattctcag aaaaaagata taaaagaatt
    10861 atataaaaaa atatatgaat cttttaaaga aaagaataaa tgattgtatt ataatccttg
    10921 tattttgcta tggtttgtta attgattttt gcatatctta cttcaacata ctataaaata
    10981 aaacataaga aaacgagtat ctccaactac ggaaatactc gctttttgat atttagaagt
    11041 gttttttgct ttgcttcttt tgtttcgatt aacgcatggt tacaaattct tcagatgcag
    11101 ttgggtgaat tgccacagtt gcatcaaagt cagccttggt tgctcccatt ttgatagcaa
    11161 cggcaaatcc ttgaatcatt tcatcaacgc cgtagccaat tccatgaagt ccgacaactt
    11221 tttcttctga accagctgtt atgagtttga aacgggattc ttgacggttg cgagtgcaag
    11281 cagagtacat agatgcaaag cttgatttat aaaccttgat ttggtcttga ccgtattctt
    11341 taatagcttg ctcttctgtc aaaccaacag ttccgatagc agggtgtgaa aagacaacag
    11401 ttggaatagt tgagtaatcc atttttgcag tagtttttcc gttaaagaga cgttcagata
    11461 gggtacgtcc ggccttgatt gcaactggag tcagttcttt ctcgcccgtt acatcaccta
    11521 gagcatagat tccctcaaca acagtatttt ggtattcatc cacttggata aagccacgtt
    11581 cgttcagagt cactccagct ttttcaagtt gcaagccctt aacgtttgga cggcgacctg
    11641 tagcccagat aacttggcta gctgtgtgac tagtaccatc ttcgaaatga atggtaatgc
    11701 cgtcagtagt tttttctaac ttgacaggga ctttgtgagt gtgaagtggt aagtttgttc
    11761 tttccatttc cttgaccaaa ccttcaacga tgtaggaatc aaaaccacgt aaaggacgat
    11821 cgcggcgaac aaagagatct gtcttgacac caaaagtgtg gagtacgcca gctaattcaa
    11881 cggcgatata accagcgcct agaatggcaa ttgactctgg aagttcttcc caggcaaata
    11941 catcatcaga agagccacct agctcagcac caggaatatt aggaatactt ggatgggcac
    12001 ctgtagcaat cacgatatgt ttagcacgaa tcagttcacc atttacgctt acagtatgag
    12061 aatctacaaa ttcagcatga ccttcaatca agtctacacc gttgcgttta aaactaccat
    12121 cataagaaga acgagcgcga tcaatgtagg cttcacgatt gcgacgtagg gttgcaaagt
    12181 caaagttaag atcagtagtc ttaaagccgt agtcttctcc aaattgatgg aaagtctcag
    12241 cgatttgcgc cccgtaccac atgatttttt taggaacaca accgacgttg acacaggttc
    12301 cacctaattt cttttcctca ataacggctg ctttggctcc atgttcacca gcacggttca
    12361 tggtagcgat tcctccgcta cctccaccga tagcaatgat atcatattct ctcattgaaa
    12421 actcctttgt aatcttttaa atagtagagc gtcttttttg atagttatat tttattcttt
    12481 ttttgatttg attgcaaaaa tctgctacgc acaaaaaatt gcaaaaaagc ttgccaaata
    12541 agtcaagata gtgtattata tatctagtac aatagaaaag caaaattccg aacgattgtt
    12601 taatcctgaa ctgtattgtt tgctggaggg aaatttggta taatagcaaa gtattgtaaa
    12661 aaagaaaagg agtttcatta tgaagaaaaa gaatggtaaa gctaaaaagt ggcaactgta
    12721 tgcagcaatc ggtgctgcga gtgtagttgt attgggtgct ggggggattt tactctttag
    12781 acaaccttct cagactgctc taaaagatga gcctactcat cttgttgttg ccaaggaagg
    12841 aagcgtggcc tcctctgttt tattgtcagg gacagtaaca gcaaaaaatg aacaatatgt
    12901 ttattttgat gctagtaagg gtgatttaga tgaaatcctt gtttctgtgg gcgataaggt
    12961 cagcgaaggg caggctttag tcaagtacag tagttcagaa gcgcaggcgg cctatgattc
    13021 agctagtcga gcagtagcta aggcagatcg tcatatcaat gaactcaatc aagcacgaaa
    13081 tgaagccgct tcagctccgg ctccacagtt accagcgcca gtaggaggag aagatgcaac
    13141 ggtgcaaagc ccaactccag tggctggaaa ttctgttgct tctattgacg ctcaattggg
    13201 tgatgcccgt gatgcgcgtg cagatgctgc agcgcaatta agcaaggctc aaagtcaatt
    13261 ggatgcaaca actgttctca gtaccctaga gggaactgta gtcgaagtca atagcaatgt
    13321 ttctaaatct ccaacagggg cgagccaagt tatggttcat attgtcagca atgaaaattt
    13381 acaagtcaag ggagaattgt ctgagtacaa tctagccaac ctttctgtag gtcaagaagt
    13441 aagctttact tctaaagtgt atcctgataa aaaatggact gggaaattaa gctatatttc
    13501 tgactatcct aaaaacaatg gtgaagcagc tagtccagca gccgggaata atacaggttc
    13561 taaataccct tatactattg atgtgacagg cgaggttggt gatttgaaac agggtttttc
    13621 tgtcaacatt gaggttaaaa gcaaaactaa ggctattctt gttcctgtta gcagtctagt
    13681 aatggatgat agtaaaaatt atgtctggat tgtggatgaa caacaaaagg ctaaaaaagt
    13741 tgaggtttca ttgggaaatg ctgacgcaga aaatcaagaa atcacttctg gtttaacgaa
    13801 tggtgctaag gtcatcagta atccaacatc ttccttggaa gaaggaaaag aggtgaaggc
    13861 tgatgaagca actaattagt ctaaaaaata tcttcagaag ctaccgtaat ggtgaccaag
    13921 aactgcaggt tctcaaaaat atcaatctag aagtgaatga gggtgaattt gtagccatca
    13981 tgggaccatc tgggtctggt aagtccactc tgatgaatac gattggcatg ttggatacac
    14041 caaccagtgg agaatattat cttgaaggtc aagaagtggc tgggcttggt gaaaaacaac
    14101 tggctaaggt ccgtaaccaa caaatcggtt ttgtctttca gcagttcttt cttctatcga
    14161 agctcaatgc tctgcaaaat gtagaattgc ccttgattta cgcaggagtt tcgtcttcaa
    14221 aacgtcgcaa gttggctgag gaatatttag acaaggttga attgacagaa cgtagtcacc
    14281 atttaccttc agaattatct ggtggtcaaa agcaacgtgt agccattgcg cgtgccttgg
    14341 taaacaatcc ttctattatc ctagcggatg aaccgacagg agccttggat accaaaacag
    14401 gtaaccaaat tatgcaatta ttggttgatt tgaataaaga aggaaaaacc attatcatgg
    14461 taacgcatga gcctgagatt gctgcctatg ctaaacgtca gattgtcatt cgggatgggg
    14521 tcatttcgtc tgacagtgct cagttaggaa aggaggaaaa ctaagatgca gaatctgaaa
    14581 tttgcctttt catctatcat ggctcacaag atgcgttctt tgcttactat gattgggatt
    14641 attatcggtg tttcatcagt tgttgtgatt atggctttgg gtgattccct atctcgtcaa
    14701 gtcaataaag atatgactaa atctcagaaa aatattagcg tctttttctc tcctaaaaaa
    14761 agtaaagatg gttcttttac tcagaaacaa tcatctttta cggtttctgg aaaggaagag
    14821 gaaattcctg ttgaaccgcc aaaaccgcaa gaatcctggg tccaagaggc agctaaactg
    14881 aagggagtgg atagttacta tgtaaccaat tcaacgaatg ccatcttgac ctatcaagat
    14941 aaaaaggttg agaatgctaa tttgacaggt ggaaacagaa cttacatgga cgctgttaag
    15001 aatgaaatta ttgcaggtcg tagtctgaga gagcaagatt tcaaagagtt tgcaagtgtt
    15061 attttgctag atgaggaatt gtccattagt ttatttgaat ctcctcaaga ggctattaac
    15121 aaggttgtag aagtcaatgg atttagttac cgggtcattg gggtttatac tagtccggag
    15181 gctaaaaggt caaaaatata tgggtttggt ggcttgccta ttactaccaa tatctccctt
    15241 gctgcgaatt ttaatataga tgaaatagct agtattgtct ttcgagtgaa tgataccagt
    15301 ttaaccccaa ctctgggtcc agaactggca cgaaaaatga cagagcttgc aggcttacaa
    15361 cagggagaat accaggtggc agatgagtcc gttgtatttg cagaaattca acaatcgttt
    15421 agttttatga cgacgattat tagttccatc gcagggattt ctctctttgt tggaggaact
    15481 ggtgtcatga acatcatgct ggtttcggtg acagagcgca ctcgtgagat tggtcttcgt
    15541 aaggctttgg gcgcaacacg tgccaatatt ttaattcagt ttttgattga atccatgatt
    15601 ttgaccttgt taggtggctt aattggcttg acaattgcaa gtggtttaac tgccttagca
    15661 ggtttgttac tgcaaggttt aatagaaggt atagaagttg gagtatcaat cccagttgcc
    15721 ctatttagtc ttgcagtttc ggctagtgtt ggtatgattt ttggagtctt gccagccaac
    15781 aaggcatcga aacttgatcc aattgaagcc cttcgttatg aatgagatca acaagatgga
    15841 cactcgtcta tcttgttttt gtatggattt ccctatcgaa attcattaaa aatgtgatat
    15901 aatgaagtgt tagaaaaaca ggtttcattt gcctggaaag gaaaaattat gtctgaaaaa
    15961 aatttttata ttacaacgcc gatttactat ccatctggga aacttcatat cggttctgcc
    16021 tacacaacta tcgcatgtga tgtcctagca cgttacaaac gcctgatggg ctacgatgta
    16081 ttttatctga caggtcttga tgaacatggt cagaaaatcc agcagaaagc ggaagaagct
    16141 ggtattacac ctcaagccta tgttgatgga atggcggttg gagttaaaga actctggcaa
    16201 ttactagata tctcatacga taaatttatc cgtacaactg atgactacca tgaaaaagtt
    16261 gtcgcacaag tctttgaacg cttacttgct caagatgata tctacttggg tgaatactct
    16321 ggttggtatt cagtatcaga cgaagaattc tttacagaaa gccagctggc agaagttttc
    16381 cgtgatgaag ctggaaatgt gactggtggt attgctccat caggtcatga ggttgaatgg
    16441 gtttctgaag aatcatactt ccttcgcctt agcaaatacc aagaccgttt ggtcgaattt
    16501 ttcaaagctc atcctgaatt tatcacgcca gatggtcgcc ttaatgaaat gctacgcaac
    16561 ttcatcgagc caggtttgga agatttggcg gtatctcgta caacctttac atggggagtg
    16621 cctgtcccat caaatccaaa acacgttgtc tacgtttgga ttgatgccct tcttaactat
    16681 gcgacagctc ttggctacgc tcaagacgaa catggtaact ttgacaagtt ctggaatgga
    16741 acagtcttcc atatggtagg aaaagatatc cttcgcttcc actctatcta ctggccaatc
    16801 cttcttatga tgttggatgt taaattacct gatcgtttga ttgcccatgg ttggtttgtc
    16861 atgaaagacg gaaaaatgtc taagtcaaaa gggaatgtcg tttaccctga aatgttggta
    16921 gagcgttatg gactagatcc acttcgttac tacctcatgc gtaaccttcc agttggttca
    16981 gacggaacct ttactcctga agactatgtc ggccgtatca actatgaatt ggctaatgac
    17041 cttgggaacc tccttaaccg tacggtttcc atgattaata agtactttga tggacaaatc
    17101 cctgcctatg tagaaggtgt gactgaattt gatcatgttc ttgctgaggt tgcagaacaa
    17161 tcaatcgcag acttccatac acacatggaa gcagttgact atccacgtgc gcttgaagca
    17221 gtctggactc tgatctctcg taccaataaa tacatcgatg agactgcacc atgggtcttg
    17281 gccaaggatg aagctcttcg tgaccaattg gcaagtgtca tgagccactt ggcagccagc
    17341 attcgtgtag ttgctcactt gattgaacca tttatgatgg aaactagtcg tgcagttttg
    17401 actcaacttg gtttggaaga agtttctagt cttgaaaact tgagtttggc tgacttccca
    17461 gcagatgtga ctgtagttgc caaaggaaca cctatctttc cacgtctaaa tatggaagaa
    17521 gaaatcgcct atatcaagga acaaatggaa ggcaataaac cagcagtcga aaaagaatgg
    17581 aatccggacg aagttgagct caaactaaac aaggatgaaa tcaagtttga agactttgac
    17641 aaggttgaaa tccgtgtcgc agaagtcaaa gaagtgtcta aagtagaagg ttcagataag
    17701 ttgcttcaat tccgcttgga tgctggtgat ggagaagatc gtcagattct ttcaggaatt
    17761 gcaaaatact atccaaatga acaagaattg gtcggcaaga aagttcaaat cattgctaac
    17821 ctcaaaccac gtaaaatgat gaaaaaatat gtcagccagg gtatgattct ctcagctgaa
    17881 catgatggca aattaaccct tctcacagtt gatccagctg taccaaatgg aagtgtgatt
    17941 gggtaaaagt agacaggact agttcaggct agttctgttt ttttatttat actcaatgaa
    18001 aatcaaagag caaactagga agctagccgc aggttgctca aaacacagtt ttgaggttgt
    18061 agatgaaact gacgaagtca gctcaaaaca cagttttgag gttgtagatg aaactgacga
    18121 agtcagtaac catacataag gtagggcgac gctgacgtgg tttgaagaga ttttcgaaga
    18181 gtattaacta ttatgcttta caaactagtg tagaagtgat atactatagg tgaagttact
    18241 agtaggtatt acaaaataga ttagaaggga aaagtgatga aagaaactca gctattaaaa
    18301 ggtgttcttg aaggttgtgt cttggatatg attggtcaaa aagagcggta tggttatgag
    18361 ttggttcaga ctttgcgaga ggctggattt gatactatcg ttccaggaac tatttatcct
    18421 ttgttgcaaa agttagaaaa aaatcaatgg ataagaggcg acatgcgccc gtcgccagat
    18481 ggtccagatc ggaagtattt ttcattaatg aaagaaggag aagagcgtgt ctcagtcttt
    18541 tggcaacaat gggacgattt gagtcaaaaa gtagaaggga ttaagaatgg gggttaaacc
    18601 atgaagaaaa tgaagtatta cgaagaaaca agcgctttgc tacatgagtt ttctgaggag
    18661 aatcaaaagt attttgagga gttgtgggaa agttttaatc ttgctggatt tctctatgat
    18721 gaagactatc tcagagagca gatctatttg atgatgctag atttctcaga agcagaacga
    18781 gatggcatga gtgcagagga ttatctaggt aagaatccta aaaaaataat gaaagagatt
    18841 ctcaagggag cacctcgcag ttctatcaaa gagtcccttt tgacgccaat tcttgtcctg
    18901 gcggtattac gttattatca actactaagt gatttttcta aaggtcctct attaacagtc
    18961 aatttgctca catttttagg gcaacttctt atttttctga ttggatttgg acttgtggcc
    19021 acaattttac gaagaagttt agtccaagat tctcctaaaa tgaaaattgg cacttacatt
    19081 gttgttggga ctatagttct tctagttgtt ttaggatatg taggaatggc aagcttcata
    19141 caagaaggag tcttttatat tccggctccc tgggatagtt tgtctgtctt tacgatttcg
    19201 ctagttatcg gtatttggaa ttggaaagaa gcggtctttc gtccatttgt cagtatgatt
    19261 attgcccatc ttgtggtggg ttctctgctc cgttattatg agtggatggg aatttcaaat
    19321 gttttcctta caaaagttat tcctttagct gtcctcttta ttggaatctt tgtcttgttc
    19381 cgtgggttta agaagataaa atggagtgaa gtatagtcaa aaagccgttg caaagcggtt
    19441 ttttgttata atgaagggaa gaatgttaga aattaaagga gaaaaatttg atgagataca
    19501 taactcttgg tcaagatgac aaagaattat cagaaattgt tctcggaatg atgagaataa
    19561 aagataaatc tgtaaaagaa gttgaagagc ttgtagaaac agcactttct gttggaatca
    19621 atgccttcga cttggctgat atttatggtc gtggtcgttg tgaagaactg ttaggtcttg
    19681 tcctaaaaaa tcgtccagat ttaagagaaa agatgtggat tcagtccaaa tgtggcattc
    19741 gcattgaaga atttacctat tttgattttt ctaaggacta tattataaaa tcagtagacg
    19801 gtattttgca aagattgaag attaatcatc tagatagctt gctccttcat cgaccagatg
    19861 ctttgatgga atctgaccaa gtagcagaag cctttgatct cctttataaa caaggtaaag
    19921 ttcgagattt tggagtttct aatcaaaatc ctatgatgat ggagttgctt aaaaaagatg
    19981 tcaagcagcc gttagctgtt aatcagctac aattgagtgc ggcttttact ccaggatttg
    20041 aatcagcttt tcatgttaat atggaagata gtcaagcagc tatgcgagat ggcagcattt
    20101 ttgaatattg ccaattacac gatgtggtca ttcaagcatg gtctgtcttg caattcgggt
    20161 attttaaagg gaactttgtt ggaaatgaga aatttcaagc tttaaatcaa gtacttgatc
    20221 gtttagctat taaatatgga gtaacctctt caactattgc catttcttgg atattgcgtt
    20281 atccagcaaa aatgcaggca gtcgtaggta caacaaatcc taagcacttg agagaagtta
    20341 gccgagcggc aaactttagc ttaacaagaa aagaatggta tgaaatttat cttgctgcag
    20401 ggaataattt gccgtaagta gtagcaggtt tgaataactc acagtcaaaa agccgtataa
    20461 agtggttttt tgctataatt aaatgaagaa tgtagaatta aaggagaaaa acatgacatt
    20521 tgaagagatc ctgcctgggt taaaggctaa gagaaaatat gtacgaactg gttggggagg
    20581 tgcggaaaac tatgtccaac tctttgatac catcgagcaa aatgggcttg cacttgaaat
    20641 gacaccttat ttcctaatca acgtttctgg agaaggagaa ggtttttcca tgtggagccc
    20701 gacagtttgt gatgttttgg caacggattg ggtagaagtg catgactaaa cgtgtactca
    20761 ttacaggagt gagttcaggg atcggattgg ctcaagctcg cctcttttta gagaagggct
    20821 atcaagttta tggagttgac caaggtgaaa agccactctt agagggtgat tttcactttt
    20881 tacagagaga tttgaccttg gacttggaac ctatttttga ctggtgccct caggtggatg
    20941 ttttgtgtaa tactgccgga gttttggatg cttacaaacc actgttggaa caaacggcgc
    21001 aggacattca agagattttt gaaatcaact acattattcc agtagagttg actcggtatt
    21061 atttgacaca aatgctggaa aataaaaagg gaatcatcat caatatgtgt tccattgctt
    21121 ctagcctagc aggtggaggt ggtcacgcct atacttcatc caagcatgcc ttggctggct
    21181 tcaccaagca gttggctcta gactatgctg aagctgggat tcaggtcttt ggtatcgctc
    21241 caggagcagt caagacagct atgaccgctg cggattttga accaggtggt ttggctgact
    21301 gggtggctag tgaaacccca atcaagcgct ggattgagcc agaggaaata gcagagctta
    21361 gtcttttttt agcaagtgga aaagcgagcg ccatgcaagg acaaatcttg acaatagatg
    21421 gtggctggtc tttgaagtag gaggagttgg atggaaatca aaaaacactt tggagtctac
    21481 gctgtttgct tagaaaatgg gaagttactc tgcattgaaa aaacgagagg cccttatcaa
    21541 catcggtatg atctacctgg aggcagtcag caacttggtg aaggactgac ggaaacgctg
    21601 actagagaag ttatggaaga gacgggattt actgttagaa gctactctaa tcctcgaatc
    21661 tacgatgttt tcgtcagaga agagttaaaa aattttatgg ttcaccatgt catggccttg
    21721 tatgatgttg aaatgaatga gagtgcacct caagttacga cttcggaagc tgtgtctgat
    21781 ggtgcgaatg attcacttgg atatatttgg atggatattc aagagattac agaagaaaat
    21841 gcatcgccat tagtcttgaa ggttaagtct gaattattag gatttccaga actggacaag
    21901 acttcttaca tgaattggaa ggtgaagtag agggataatg gaactattta aaacatggaa
    21961 gaaaaatatg gttctctatg gtcttaaatc tcaaattgga actgtctacc gaaacaatga
    22021 taggacaaca agcttttatg atgttgggaa ttttctatac ctagcagggg agttggattc
    22081 cagattttgg gaagattttg ttagaaaata tggtttagat tataagatta ttatttcaga
    22141 aaatactaat tggcaagatt ttctgcatcg aaaagtgggg ctaaattctt ttactcgcta
    22201 ttcttttaaa gataaggcaa attttcaagt tgaattttta aataatctag ttactcattt
    22261 agaggaaggt tacaatattg tgcctattga taatcatatt tataactgct tttctacgga
    22321 agaatggtca caggatttac agggggattt tgagtcctat caggattttg ttttaaaagg
    22381 tggatttggc tttgtgattc ttaaaaataa tgaactgatt gctgggattt cctcagggtt
    22441 agtttaccgt aaagcagttg aagtggaagt tgcaactaga ccaaacgaac aaggaaatgg
    22501 atttgctaaa aagcttggtg ctgcaatgat tctagagagt ttaaatagag atatgtttcc
    22561 actttgggat gctcataatg aggcttccaa aaaagtagca gaatttttag gatatgagtt
    22621 atctgaacct tatgaagctt ttgaactaga ggaaattttg atataattat atatgatatt
    22681 gtatctttta agacgaggtg aatggctatg agaaatcaac ttgcccttag tggcgaaaaa
    22741 attcttgaaa aaatttatcc tcaactattt caccacgtcg gcatgattcg tggggaatat
    22801 ttgttgagag agcttaatca aaacatcata ttagcaagtt gtcagcaatt tgtaaaagat
    22861 tatctagaga ctatctgctc cctgtactca gatgaagaag tttggtatcg ttttactgaa
    22921 ttaacgaata cagaagccaa ttgtttagtg gggactaaag agttttttga cgaagggcat
    22981 cccttgtttg gctatagagg aactaggcgt ttactggcgt gtttggatga atttcaggct
    23041 gaagcacatg tcgttacaga agtttatcaa accaactcca atctatctgt tatctttcct
    23101 tttgtcaatg atgccgacca attaaaacaa gctattacag tattgcgtca gtatggcttt
    23161 actgggaaag tcggaacgat gattgaatta ccgtcagcgt attttgactt atctagtata
    23221 ctggaaacgg gcatttcaaa gattgtagtt ggaatgaatg atttgacttc ctttgttttt
    23281 gcgactatga gaaacagtca atggcatgat atggaaagtc caataatgtt agatatgcta
    23341 agagatatgc aggataaagc aagaaagaac aagattaatt ttgctgtagc aggctatctg
    23401 aatacttctt tcatacaaaa aatgaatcag ttgggtatca agtgcattat ccactacagt
    23461 tctattccag agatttttga tttagagatt gaccatccag atcatcttaa acacataaaa
    23521 gaagaaagta aaaaattaca aaggagtacc catgataccg caagaaatgt ggaataaata
    23581 caagcaaatc aatcctttga tcggagatga aatcgatgct tgggcttttg gagttgaacc
    23641 agacctttta gcggatttgg tgtttaaagg agaaaagaca gcaacagcat cagcctatga
    23701 cctctatgta ctagaagacg aaccacttcc ccaagtaggg accttcgata tcattttaga
    23761 tagtcaaaat cagtctgtct gcattgtcga aattacaaag gtttctgttg aactcttcaa
    23821 tcaagtttct gcgcaacatg cctttaagga aggtgaggga gacaaatcac ttgcctattg
    23881 gcgccaggtt catgaggact ttttcacaaa ctgtttgggt gaagtagggc tgacttttac
    23941 acctgaaagc aaggttgttt tagaagaatt tcgcaaggtc tacccactgt agactattag
    24001 aaggaagaaa gttttggaaa tcgctgtcca atcctttttt ctcaagcaaa atatgatata
    24061 ataagtttgt ttgaagaaga gcagcagctc ttaaacttag aataggagaa aactatgcaa
    24121 gcagttgaac attttattaa gcaatttgtt cctgaacatt atgatttatt tttagatttg
    24181 agtcgtgaga ccaagacttt ttctgggaaa gtgaccatca ctggtcaagc acagagtgac
    24241 cgcatctccc tccaccaaaa agacttggaa atcacctctg tagaagttgc aggtcaagct
    24301 cgtccattta cagttgacca tgacaatgaa gcccttcata tcgaattggc tgaggctggt
    24361 caagttgaat tggttcttgc cttttctggt aaaattacag acaacatgac agggatttac
    24421 ccttcttatt atacagttga tggagtcaag aaggaggtct tgtctactca gttcgagagc
    24481 cattttgcgc gcgaagcttt cccatgtgtg gatgagcctg aagccaaagc aacttttgac
    24541 ctctctcttc gctttgacca agcagaaggt gaattggcct tgtcaaacat gccagaaatc
    24601 gatgttgaaa accgtaagga aacaggtatc tggaagtttg agacaacacc tcgcatgtct
    24661 tcttacttgt tggcctttgt tgctggtgat ttgcaagggg tgaccgctaa aactaaaaat
    24721 ggtaccctgg taggtgtcta ctcaaccaaa gcacatccac tttcaaatct tgatttctca
    24781 ctggatatcg ctgttcgctc tatcgagttt tacgaagatt actatggagt taagtatcca
    24841 attcctcaat ctctccacat cgcccttcct gacttctcag ctggtgctat ggaaaactgg
    24901 ggtcttgtga cctaccgtga agtttacttg gttgtcgatg agaactctac atttgctagc
    24961 cgtcaacaag ttgcccttgt tgtggcccat gaattggctc accaatggtt tgggaacctc
    25021 gtgactatga aatggtggga tgacctttgg ctcaatgaaa gtttcgctaa tatgatggaa
    25081 tacgtctgtg tggataccat cgaaccaagc tggaatatct ttgaagattt ccaaacaggt
    25141 ggagtacctc ttgctcttga acgtgacgct actgatggcg ttcagtctgt ccacgtcgaa
    25201 gttaaacatc cagatgaaat caatacactc tttgacggcg ctatcgtcta tgccaaagga
    25261 agccgtctca tgcacatgct tcgccgttgg ctaggagatg ctgattttgc taaaggtttg
    25321 catgcctact ttgaaaaaca ccaatacagc aacaccattg gtagtgacct ttgggatgcc
    25381 cttggtcaag cgtcaggacg tgatgtcgca gccttcatgg attcttggtt ggaacagcct
    25441 ggttacccag ttcttactgt caaagttgaa aatgatgtct tgaagatttc acaaaaacaa
    25501 ttcttcatcg gtgagaacga agacaagaac cgtctctggg tggtgcccct caatagcaac
    25561 tggaaaggct tgcctgatac actcgaaact gaaagtatcg aaatccctgg ctacgcagct
    25621 cttcttgctg aaaatgaagg agctcttcgt ctcaacactg aaaatactgc ccactatatt
    25681 accgactatc aaggagactt gttagaagct gttcttgctg agctagagac acttgataac
    25741 acaagcaaac tgcaaattgt tcaagaacgt cgtttgttgg ctgaggcagg gcacatttct
    25801 tatgcagact tgcttccagt tcttgataaa cttgctaagg aagagtctta tctggtggtt
    25861 tcagctgttt ctcaagtgat ttcagccctt gagcgcttta ttgatgaagg aacggatgct
    25921 gaaacagcct tcaaaggact ggttgctaaa ttggctcgtc ataactatga ccgtcttggt
    25981 tttgaagcta aagacggaga atcagatgag gatgaattgg ttcgtcagct ggctgtttcg
    26041 atgatgattc gctcaaatga tgcagaagct cgtcaagtcg ctagccaaat cttcgcaaca
    26101 cacaaggaga atcttgcaga actcccagca gctattcgtt cacaagttct gattaatgag
    26161 atgaaacatc atgagactaa agacttgtta gcactttatc ttgatactta tactcacgca
    26221 acagatgctg tctttaaacg ccagttggca gcagctcttg catacagtac agatgcggat
    26281 aatatccaaa acttgattac ttcttggaag gacaaatttg tggtcaaacc acaggacttg
    26341 tctgcttggt attaccaatt cctagctcat caagcaactc agaaaacagc ttggtcttgg
    26401 gcgcgtgaaa actgggcttg gattaaggca gcccttggag gagatatgag ctttgatagc
    26461 tttgttatcc ttcctgctca tgtatttaag actcagcaac gcttggcgga atacaaggag
    26521 ttctttgagc cgcaactttc tgaccttgct cttagccgta acatcggtat gggaatcaag
    26581 gaaattgcag cacgtgttga cttgattagc cgtgaaaaag ctgcagtcga agcagttgtt
    26641 cttcaatacg gaaatgcata aataagccta aaataaaaag aaa
//
LOCUS       DAVHTH010000027        26088 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.027, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000027 DAVHTH010000000
VERSION     DAVHTH010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 26088)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26088)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26088
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.027"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            complement(<1..230)
                     /locus_tag="VVR63_001176"
     CDS             complement(<1..230)
                     /locus_tag="VVR63_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEU6129198.1"
                     /translation="MKHFDTIVIGGGPAGMMATISSSFYGQKTLLIEKNRKLGKKLAG
                     TGGGRCNVTNNGSLDNLLAGIPGNGRFLYSVFS"
     gene            complement(289..1134)
                     /locus_tag="VVR63_001177"
     CDS             complement(289..1134)
                     /locus_tag="VVR63_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEU6129199.1"
                     /translation="MTWKIIADSGCDYRQLPTPAINTTFVSVPLTIQVADQVFVDDAS
                     LDIDQMMETMYATAEASKSACPSPDDYLRAFEGAKNIFLVTITGTLSGSHNSAQLAKN
                     IYLEDHPDTKIHVIDSLSAGGEVDLLVEKLNDLIDQGLSFEEVVEAITAYQEKTKLLF
                     VLAKVDNLVKNGRLSKLIGTVVGLLNIRMVGKASETGTLELLQKARGSKKSVQAAYDE
                     LVKAGYAGGRIVMAQRNNEKCCQQLSERIRETFPQADIKILPTSGLCSFYAEEGGLLM
                     GYEID"
     gene            1259..1816
                     /locus_tag="VVR63_001178"
     CDS             1259..1816
                     /locus_tag="VVR63_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEU6129200.1"
                     /translation="MSERRISEKSLENLRKSNQESNLLTREAIETALLQLLEKKELTK
                     ISISELVKRAGVSRAAFYRNYDSKEEILESVFKRTVHNIMEQLHHYDLKTDLYLVWVH
                     LFREARKEARVIQLALDYHLEKIFVQAMQEFLEKYHGKSKGVSSYLHSFWSSAIVSVL
                     LKWIKDGMKVPAEKIADLGLPFFKK"
     gene            1835..2302
                     /locus_tag="VVR63_001179"
     CDS             1835..2302
                     /locus_tag="VVR63_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000138511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HEU6129201.1"
                     /translation="MTEKRLAWDEYFAAQALLIANRSTCKRAKVGAILVKDNKVISTG
                     YNGSVSGTEHCIDHECLVIEGHCVRTLHAEVNAILQGAERGVPKGFTAYVTHFPCLNC
                     TKQLLQVGCKRVVYINQYRMDDYAQYLYQEKGTELTHLPLETVQTALKEADLM"
     gene            2391..3020
                     /gene="upp"
                     /locus_tag="VVR63_001180"
     CDS             2391..3020
                     /gene="upp"
                     /locus_tag="VVR63_001180"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HEU6129202.1"
                     /translation="MGKIEVINHPLIQHKLSILRRTDTSTKAFRELVDEIAMLMGYEV
                     LRDLPLEDVEIETPITKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGM
                     YRDEETLQPVEYLVKLPEDIDQRQIFVVDPMLATGGSAILAVDSLKKRGASNIKFVCL
                     VSAPEGVKALQEAHPDVEIFTAALDERLNEHGYIVPGLGDAGDRLFGTK"
     gene            3194..3784
                     /gene="clpP"
                     /locus_tag="VVR63_001181"
     CDS             3194..3784
                     /gene="clpP"
                     /locus_tag="VVR63_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit
                     ClpP"
                     /protein_id="HEU6129203.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
                     SMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN"
     gene            3863..4111
                     /locus_tag="VVR63_001182"
     CDS             3863..4111
                     /locus_tag="VVR63_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HEU6129204.1"
                     /translation="MFEKVNRSGLIIYLYYNRDAKKLQDYGDITYHSKKHRYLQLYVP
                     TQEVEQLVGRLSKEKFIKKVRVCHIQELETPFVGNLYR"
     gene            4213..5373
                     /locus_tag="VVR63_001183"
     CDS             4213..5373
                     /locus_tag="VVR63_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU6129205.1"
                     /translation="MKKKFALSFVALASVALLAACGEVKSGAVNTAGNSVEEKTIKIG
                     FNFEESGSLAAYGTAEQKGAQLAVDEINAAGGIDGKQIEVVDKDNKSETAEAASVTTN
                     LVTQSKVSAVVGPATSGATAAAVANATKAGVPLISPSATQDGLTKGQDYLFIGTFQDS
                     FQGKIISNYVSEKLNAKKVVLYTDNASDYAKGIAKSFRESYKGEIVADETFVAGDTDF
                     QAALTKMKGKDFDAIVVPGYYNEAGKIVNQARGMGIDKPIVGGDGFNGEEFVQQATAE
                     KASNIYFISGFSTTVEVSAKAKAFLDAYRAKYNEEPSTFAALAYDSVHLVANAAKGAK
                     NSGEIKNNLAKTKDFEGVTGQTSFDADHNTVKTAYMMTMNNGKVEAAEVVKP"
     gene            5641..6510
                     /locus_tag="VVR63_001184"
     CDS             5641..6510
                     /locus_tag="VVR63_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HEU6129206.1"
                     /translation="MLQQLVNGLILGSVYALLALGYTMVYGIIKLINFAHGDIYMMGA
                     FIGYFLINSFQMNFFVALIVAMLATAILGVVIEFLAYRPLRHSTRIAVLITAIGVSFL
                     LEYGMVYLVGANTRAFPQAIQTVRYDLGPISLTNVQLMILAISLILMILLQVIVQKTK
                     MGKAMRAVSVDSDAAQLMGINVNRTISFTFALGSALAGAAGVLIALYYNSLEPLMGVT
                     PGLKSFVAAVLGGIGIIPGAALGGFVIGLLETFATAFGMSDFRDAIVYGILLLILIVR
                     PAGILGKNVKEKV"
     gene            6514..7470
                     /locus_tag="VVR63_001185"
     CDS             6514..7470
                     /locus_tag="VVR63_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HEU6129207.1"
                     /translation="MKENLKVNILWLLLLLAGYSLISVLVSVGVLNLFYVQILQQIGI
                     NIILAVGLNLIVGFSGQFSLGHAGFMAIGAYAAAIIGSKSPTYGAFFGAMLVGALLSG
                     AVALLVGIPTLRLKGDYLAVATLGVSEIIRIFIINGGSLTNGAAGILGIPNFTTWQMV
                     YFFVVITTIATLNFLRSPIGRSTLSVREDEIAAESVGVNTTKIKIIAFVFGAITASIA
                     GSLQAGFIGSVVPKDYTFINSINVLIIVVFGGLGSITGAIVSAIVLGILNMLLQDVAS
                     VRMIIYALALVLVMIFRPGGLLGTWELSLSRFFKKSKKEEQN"
     gene            7470..8234
                     /locus_tag="VVR63_001186"
     CDS             7470..8234
                     /locus_tag="VVR63_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6129208.1"
                     /translation="MALLEVKQLTKHFGGLTAVGDVTLELNEGELVGLIGPNGAGKTT
                     LFNLLTGVYEPSEGTVTLDGHLLNGKSPYKIASLGLGRTFQNIRLFKDLTVLDNVLIA
                     FGNHHKQHVFTSFLRLPAFYKSEKELKAKALELLKIFDLDGDAETLAKNLSYGQQRRL
                     EIVRALATEPKILFLDEPAAGMNPQETAELTELIRRIKDEFKITIMLIEHDMNLVMEV
                     TERIYVLEYGRLIAQGTPDEIKTNKRVIEAYLGGEA"
     gene            8234..8944
                     /locus_tag="VVR63_001187"
     CDS             8234..8944
                     /locus_tag="VVR63_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6129209.1"
                     /translation="MSMLKVENLSVHYGMIQAVRDVSFEVNEGEVVSLIGANGAGKTT
                     ILRTLSGLVRPSSGKIEFLGQEIQKIPAQKIVAGGLSQVPEGRHVFPGLTVMENLEMG
                     AFLKKNREENQANLKKVFSRFPRLEERKNQDAATLSGGEQQMLAMGRALMSTPKLLLL
                     DEPSMGLAPIFIQEIFDIIQDIQKQGTTVLLIEQNANKALAISDRGYVLETGKIVLSG
                     TGKELASSEEVRKAYLGG"
     gene            9252..9908
                     /locus_tag="VVR63_001188"
     CDS             9252..9908
                     /locus_tag="VVR63_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEU6129210.1"
                     /translation="MAVKDFMTRKVVYISPDTTVSHAADLMREQGLHRLPVIENDQLV
                     GLVTEGTIAQASPSKATSLSIYEMNYLLNKTKVKDVMIRDVVTVSGYASLEDATYLML
                     KNKISILPVVDNHQVYGVITDRDVFQAFLEIAGYGEEGIRVRFVTEDEVGVLGKIVSL
                     IVEENLNISHTVNIPRKDGKVIIEVQIDGSIDLPALKEKFEANGIQVEEIARTSAKVL
                     "
     gene            10016..11111
                     /gene="prfB"
                     /locus_tag="VVR63_001189"
     CDS             join(10016..10087,10089..11111)
                     /gene="prfB"
                     /locus_tag="VVR63_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511312.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HEU6129211.1"
                     /translation="MDISVIRQKIDANREKLASFRGSLDLEGLEEEIAILENKMTEPD
                     FWNDNIAAQKTSQELNELKNTYNTFHKMEELQDEVEILLDFLAEDESVHDELVAQLAE
                     LDKIMTSYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDMLLRMYTRYGNAKGFKV
                     EVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFTSVE
                     VMPELDDTIEVEIREDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVQSTVDRT
                     QYGNRDRAMKMLQAKLYQMEQEKKAAEVDSLKGEKKEITWGSQIRSYVFTPYTMVKDH
                     RTSFEVAQVDKVMDGDLDGFIDAYLKWRIS"
     gene            11129..11821
                     /gene="ftsE"
                     /locus_tag="VVR63_001190"
     CDS             11129..11821
                     /gene="ftsE"
                     /locus_tag="VVR63_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HEU6129212.1"
                     /translation="MSIIEMRDVVKKYDNGTTALRGVSVSVQPGEFAYIVGPSGAGKS
                     TFIRSLYREVKIDKGSLSVAGFNLVKIKKKDIPLLRRSVGVVFQDYKLLPKKTVYENI
                     AYAMEVIGENRRNIKRRVMEVLDLVGLKHKVRSFPNELSGGEQQRIAIARAIVNNPKV
                     LIADEPTGNLDPDNSWEIMNLLERINLQGTTILMATHNSQIVNTLRHRVIAIENGRVV
                     RDESKGEYGYDD"
     gene            11814..12740
                     /locus_tag="VVR63_001191"
     CDS             11814..12740
                     /locus_tag="VVR63_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6129213.1"
                     /translation="MISRFFRHLFEALKSLKRNGWMTVAAVSSVMITLTLVAIFASVI
                     FNTAKLATDIENNVRVVVYIRKDVEDNSQTIEKEGQTVTNNDYHKVYDSLKNMSTVKS
                     VTFSSKEEQYEKLTEIMGDNWKIFEGDANPLYDAYIVEANTPNDVKTIAEDAKKIEGV
                     SEVQDGGANTERLFKLASFIRVWGLGIAALLIFIAVFLISNTIRITIISRSREIQIMR
                     LVGAKNSYIRGPFLLEGAFIGLLGAIAPSVLVFIVYQIVYQSVNKSLVGQNLSMISPD
                     LFSPLMIALLFVIGVFIGSLGSGISMRRFLKV"
     gene            13026..15206
                     /locus_tag="VVR63_001192"
     CDS             13026..15206
                     /locus_tag="VVR63_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000974069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEU6129214.1"
                     /translation="MMKDTFKNVLSFEFWQKFGKALMVVIAVMPAAGLMISIGKSIVM
                     INPTFAPLVITGGILEQIGWGVIGNLHILFALAIGGSWAKERAGGAFAAGLAFILINR
                     ITGTIFGVSGDMLKNPDAMVTTFFGGSIKVADYFISVLEAPALNMGVFVGIISGFVGA
                     TAYNKYYNFRKLPDALSFFNGKRFVPFVVILRSAIAAILLAAFWPVVQTGINNFGIWI
                     ANSQETAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYDILTGAAKGTQVFG
                     QDPLWLAWVTDLVNLKGTDASQYQHLLDTVHPARFKVGQMIGSFGILMGVIVAIYRNV
                     DADKKHKYKGMMIATALATFLTGVTEPIEYMFMFIATPMYLVYSLVQGAAFAMADVVN
                     LRMHSFGSIEFLTRTPIAISAGIGMDIVNFVWVTVLFAVIMYFIANFMIQKFNYATPG
                     RNGNYETAEGSEETSSEVKVAAGSQAVNIINLLGGRVNIVDVDACMTRLRVTVKDADK
                     VGNAEQWKAEGAMGLVMKGQGVQAIYGPKADILKSDIQDILDSGEIIPETLPSQMTEA
                     QQNTVHFKDLTEEVYSVADGQVVALEQVKDPVFAQKMMGDGFAVEPANGNIVSPVSGT
                     VSSIFPTKHAFGIVTEAGLEVLVHIGLDTVSLEGKPFTVHVAEGQKVAAGDLLVTADL
                     DAIRAAGRETSTVVVFTNGDAIKSVKLEKTGSLAAKTAVAKVEL"
     gene            15258..16073
                     /locus_tag="VVR63_001193"
     CDS             15258..16073
                     /locus_tag="VVR63_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEU6129215.1"
                     /translation="MKFLTLNTHSWMEKEAEEKFQILLEDILEKDYDLICFQEINQEM
                     TSSEVEVNDLYQALPAAEPIHQDHYVRLLVEKLLEQGKNYYWTWAYNHIGYDRYHEGV
                     AILSKTPIEAREILVSDVDDPTDYHTRRVALAETVVDGKELAVASVHLSWWDKGFQEE
                     WARFEAVLKKLNKPLLLAGDFNNPAGQEGYQAILASPLGLQDAFEVAQEKSGSYTVPP
                     EIDGWKGNTEPLRIDYVFTTKELAVENLHVVFDGNKSPQVSDHYGLNAILNWK"
     gene            16213..17556
                     /locus_tag="VVR63_001194"
     CDS             16213..17556
                     /locus_tag="VVR63_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU6129216.1"
                     /translation="MSFTKFQFKNYIREALKELKFTTPTEVQDKLIPIVLAGRDLVGE
                     SKTGSGKTHTFLLPIFQQLDEASDSVQAVITAPSRELATQIYQVARQISAHSDVEVRV
                     VNYVGGTDKARQIEKLESNQPHIVIGTPGRIYDLVKSGDLAIHKAKTFVVDEADMTLD
                     MGFLETVDKIAGSLPKDLQFMVFSATIPQKLQPFLKKYLSNPVMEKIKTKTVISDTID
                     NWLISTKGHDKNAQIYQLTQLMQPYLAMIFVNTKTRADELHSYLTAQGLKVAKIHGDI
                     APRERKRIMNQVQNLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLPGTAITLYQPSDDSDIRELEKLGIKFSPKMVKDGEFQDTYDRDRRANREKKQDK
                     LDIEMIGLVKKKKKKVKPGYKKKIQWAVDEKRRKTKRAENRARGRAERKAKRQTF"
     gene            17771..18961
                     /locus_tag="VVR63_001195"
     CDS             17771..18961
                     /locus_tag="VVR63_001195"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HEU6129217.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TAVYTGSVHVFGEISTNAYVDINRVVRDTIAEIGYTNTEYGFSAETVGVHPSLVEQSP
                     DIAQGVNEALEVRGNADQDPLDLIGAGDQGLMFGFAVDETEELMPLPIALSHKLVRRL
                     AELRKSGEISYLRPDAKSQVTVEYDENDRPVRVDTVVISTQHDPEATNEQIHQDVINK
                     VIKEVIPSSYLDDKTKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLAKKAEVQLAYAIGVAQPVSVRIDTFGTGTVA
                     ESQLEKAARQIFDLRPAGIIQMLDLKRPIYRQTSAYGHMGRTDIDLPWERLDKVDALK
                     EAVK"
     gene            19514..20449
                     /locus_tag="VVR63_001196"
     CDS             19514..20449
                     /locus_tag="VVR63_001196"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HEU6129218.1"
                     /translation="MVSTKTQIAGFEFDNCLMNAAGVACMTIEELEEVKNSAAGTFVT
                     KTATLDFRQGNPEPRYQDVPLGSINSMGLPNNGLDYYLDYLLDLQEKESNRTFFLSLV
                     GMSPEETHTILKKVQESDFRGLTELNLSCPNVPGKPQIAYDFETTDRILAEVFAYFTK
                     PLGIKLPPYFDIVHFDQAAAIFNKYPLKFVNCVNSIGNGLYIEDESVVIRPKNGFGGI
                     GGEYIKPTALANVHAFYQRLNPQIQIIGTGGVLTGRDAFEHILCGASMVQVGTTLHKE
                     GVSAFDRITNELKAIMVEKGYESLEDFRGKLRYID"
     gene            20483..21520
                     /locus_tag="VVR63_001197"
     CDS             20483..21520
                     /locus_tag="VVR63_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEU6129219.1"
                     /translation="MLAIEESQKLTLSNLPSLSLFTGTDQGQFEVMKSQVLKQIGYDS
                     ADLNFAYFDMKEVVYKDVELELVSLPFFADEKIVILDYFMDITTAKKRFLTDDELKSF
                     EEYLDNPSPTTKLIIFAEGKLDSKRRLVKLLKRDAKAFDAVEVKEQELRQYFQKWSQK
                     QGLQFTNHSFENLLIKSGFQFSEIQKNLLFLQSYKADSVIEEEDIVNAIPKTLQDNIF
                     DLTQFILTKKMDQARDLVRDLTLQGEDEIKLIAVMLGQFRTFTQVKILAESGQTESQI
                     ASSLGSYLGRNPNPYQIKFALRDSRGLSLSFLKQAISYLIETDYQIKTGLYEKGFLFE
                     KALLQIASQVN"
     gene            21661..22266
                     /locus_tag="VVR63_001198"
     CDS             21661..22266
                     /locus_tag="VVR63_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HEU6129220.1"
                     /translation="MAIILPELPYAYDALEPYIDAETMHLHHDKHHQTYVNNANAALE
                     KHPEIGEDLEALLADVESIPADIRQALINNGGGHLNHALFWELMTPEKTAPSAELAAA
                     IDATFGSFEEFQAAFTAAATTRFGSGWAWLVVNKEGKLEVTSTANQDTPISEGKKPIL
                     GLDVWEHAYYVKYRNVRPDYIKAFFSVINWNKVDELYAAAK"
     gene            22424..22954
                     /locus_tag="VVR63_001199"
     CDS             22424..22954
                     /locus_tag="VVR63_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HEU6129221.1"
                     /translation="MRKEIAPELYNYNKFPGPEFHLHGDKVETEGIAFSLVENIKDAF
                     DVTTFNQRFSEVLTKFDYIVGDWSNEQLRLRGFYKDDRTEEKLEKISRLQDYLLEYCS
                     YGCAYFVLENEAPKRASFDKKMRKTEEETPSRKGKKPTQTKRKSNADKKNRRRQKDQH
                     SQKEDKEQRHFVIRQK"
     gene            22975..23877
                     /locus_tag="VVR63_001200"
     CDS             22975..23877
                     /locus_tag="VVR63_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S rRNA methyltransferase"
                     /protein_id="HEU6129222.1"
                     /translation="MKPSIHSLVHQTMQEWVLEQGEKKFRADQIWEWLYRKRVQSFEE
                     MTNLSKDLIAKLNDQFVVNPLKQRIVQESADGTVKYLFELPDGMLIETVLMRQHYGLS
                     VCVTTQVGCNIGCTFCASGLIKKQRDLNNGEIVAQIMLVQKYFADEGVQVNLAVSLHA
                     PNNELRSSTMKINRAFPIEKLFAAIEYYIETTNRRVTFEYIMLNEVNDGVEQALELAE
                     LLKNIKKLSYVNLIPYNPVSEHDQYSRSPKERVLAFYDTLKKKGVNCVVRQEHGTDID
                     AACGQLRSNTMKRDRQKAVAAVNP"
     gene            23877..24359
                     /locus_tag="VVR63_001201"
     CDS             23877..24359
                     /locus_tag="VVR63_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEU6129223.1"
                     /translation="MMKKTYNHILVWGVIFYSICIVCFCFTPQEQSTVGVGTPGIQHL
                     GRLVFLLTPFNSLWKLGEVSDIGQLCWIFLQNVLNVFLFFPLIFQLLYLFPNLRKTKK
                     VLLFSFLVSLGIECTQLILDFFFDFNRVFEIDDLWTNTLGGYLAWLLYKRLHKNKIRN
                     "
     gene            24361..25902
                     /locus_tag="VVR63_001202"
     CDS             24361..25902
                     /locus_tag="VVR63_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002918612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEU6129224.1"
                     /translation="MSILEVKNLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGKMLPDEGKVEWSKYVTAGYLDQHSVLAERQSVRDVLRTAFDELFKAEARIN
                     DLYMKMAEDGADVDALMEEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMDTDVT
                     SLSGGQRTKVLLAKLLLEKPDILLLDEPTNYLDAEHIDWLKRYLQNYENAFVLISHDI
                     PFLNDVINIVYHVENQQLTRYSGDYYQFQEVYAMKKSQLEAAYERQQKEIADLKDFVA
                     RNKARVATRNMAMSRQKKLDKMDIIELQSEKPKPSFDFKPARTPGRFIFQAKNLQIGY
                     DRPLTKPLNLTFERNQKVAIIGANGIGKTTLLKSLLGIISPIAGEVERGDYLELGYFE
                     QEVEGGNRQTPLEAVWNAFPALNQAEVRAALARCGLTTKHIESQIQVLSGGEQAKVRF
                     CLLMNRENNVLVLDEPTNHLDVDAKDELKRALKEYRGSILMVCHEPDFYEGWIDQIWD
                     FNNLT"
     gene            complement(25957..>26088)
                     /locus_tag="VVR63_001203"
     CDS             complement(25957..>26088)
                     /locus_tag="VVR63_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU6129225.1"
                     /translation="TNNLIKLIKRNAFGFRNFENFKKRIFIALNIKKERTNFVLSRA"
BASE COUNT         7887 a         4799 c         5708 g         7694 t
ORIGIN      
        1 gagaaaacac tgtaaagaaa gcgtccgttt ccaggaattc cagctagcag gttgtctaag
       61 ctaccattgt tggtcacatt gcaacgtccc ccaccagtcc cagctaattt ttttccaagt
      121 ttccgatttt tttcgatgag gagggttttc tgtccataaa agctactgga aatcgtagcc
      181 atcataccag caggtccccc accgatgaca atagtatcaa aatgtttcat agctctattg
      241 taccacaaaa aaacaagaga tgatggtcac ctcttgtcaa gaatgcaatt aatcaatttc
      301 atagcccatc agcaaaccgc cctcttctgc atagaaactg cagagaccag aggttggtag
      361 aattttaata tccgcttgtg ggaaggtttc acggattcgc tctgagagct gttgacaaca
      421 tttttcgtta ttgcgttggg ccatgacaat acggccacca gcatatccag cttttactaa
      481 ctcatcatag gcagcttgaa ctgatttctt tgatcccctt gctttttgta gcaattcgag
      541 agtcccagtt tcactagctt ttccgaccat acgaatgttg agaaggccaa cgaccgtacc
      601 gataagcttg ctcaaacggc cgttcttcac caagttatcg actttggcta ggacaaagag
      661 caacttagtt ttttcttgat aggcggtgat agcttcaacc acttcttcaa aagacaagcc
      721 ctggtcaatc aagtcattca atttttctac gagtaggtca acttcaccac cagcagataa
      781 actatcaatc acatgaatct tagtgtcagg atggtcttcc agataaatat tctttgctag
      841 ttgagcacta ttgtgactgc cagaaagggt acctgtgatg gttactagga aaatgttttt
      901 ggcaccttca aatgctcgca aatagtcatc tgggcttgga caagccgatt ttgaagcttc
      961 tgcagttgca tacatggttt ccatcatttg gtcaatatcg agactggcgt catcaacaaa
     1021 gacctgatca gctacttgaa tggttaaggg gacgcttaca aaggttgtgt taatagctgg
     1081 tgttggcagt tgacgataat cacaaccaga gtcagcaata attttccaag tcatagaaat
     1141 tctccatctt tgtcagttat acattgacaa aggttctgtc tttttttaca attatatcat
     1201 gaaaaccctt gaaacaaaag catcatccgt ctgttgtgac aagtagaaag aaaatgttat
     1261 gtctgaacgt agaatctctg aaaagtctct tgaaaatctc agaaaatcaa accaagaatc
     1321 caatttatta accagagaag ccattgaaac agccctcttg caactcttgg aaaaaaagga
     1381 gctgaccaag attagtattt ctgaattggt caaacgtgcg ggtgtttcgc gtgcggcctt
     1441 ttatcgcaat tatgactcca aagaggaaat tttagagagc gtctttaaac gaactgtcca
     1501 caatattatg gaacagctgc atcattacga tttaaagaca gacctttatt tggtttgggt
     1561 tcaccttttc cgggaggcca gaaaggaagc tagagtgatt caattggcct tggattacca
     1621 tctggaaaaa atctttgtcc aagccatgca ggaatttcta gaaaaatacc atgggaaatc
     1681 aaaaggtgtc agctcttatc ttcattcctt ctggagctca gccatcgtct ctgtccttct
     1741 aaaatggatc aaggatggca tgaaggtacc agctgaaaag attgcagatt taggtttacc
     1801 attttttaaa aaatagagaa aaaggagaaa agagatgact gaaaaaagac tggcctggga
     1861 tgagtatttt gcagcccaag ccctactaat tgcgaatcgt tccacttgta aacgtgctaa
     1921 agtgggcgcg attctggtaa aagataataa ggttatttcc actggttaca atggttcggt
     1981 gtcagggact gagcattgta ttgatcacga atgtttggtc attgaaggcc actgtgttcg
     2041 cacccttcac gctgaggtca atgctatcct tcaaggtgct gagcgtggtg ttcccaaagg
     2101 ctttacagcc tatgtaaccc attttccttg tctcaactgt acaaaacaat tgcttcaggt
     2161 cggctgcaag cgtgtggttt atatcaacca gtaccgaatg gacgactacg cccaatacct
     2221 ttatcaagaa aaagggacag aattgaccca tttaccactt gagacagtac agacagctct
     2281 taaagaggct gatctaatgt aaaaattatc aaaaataaat ggtttagaaa gatttttaaa
     2341 ccgttttttg gtataataag aagaataaat tgaaagaagg aattccaaaa atgggaaaaa
     2401 ttgaagttat taatcaccca ctgattcaac acaaattgtc aatcttgcgt cgtacagata
     2461 cttctacaaa agcttttcgt gagctagtag atgagattgc aatgttgatg gggtatgaag
     2521 tacttcgtga tcttccacta gaagatgtgg aaatcgaaac accaattaca aaaacagttc
     2581 aaaaacaatt ggcaggtaag aaattggcca tcgtcccaat cttgcgtgca ggtatcggga
     2641 tggttgatgg tctcttgagc ttggttccag ctgctaaagt tggccacatc ggtatgtacc
     2701 gtgatgaaga aacacttcaa ccagttgaat acttggtgaa attgcctgag gacattgacc
     2761 aacgtcaaat ttttgtagta gacccaatgt tggcaacagg tggctcagca atcttggctg
     2821 ttgattctct taaaaaacgt ggcgcatcaa atatcaaatt tgtctgcctt gtatctgctc
     2881 cagagggtgt aaaagccctt caagaagctc atccagatgt agaaatcttt acagcagcct
     2941 tggatgaacg tttgaacgaa cacggttata tcgttccagg tcttggagat gctggagacc
     3001 gcttgttcgg tacaaaataa gatcgaaaag aagaatgact tggaaaagta tttccagtca
     3061 cgaaaggagg ttgggttttt gtttctgtct aatgaaagca gagcaaaaat ttgacctttt
     3121 ttgaccaaga tattataata gtcttatctt cagtcatttg accaacaaaa ttaaaactca
     3181 aaaggagaaa tgaatgattc ctgtagttat tgaacaaaca agccgtggag aacgttctta
     3241 cgatatttac tcacgtcttc tcaaagaccg catcattatg ctgacaggtc cggttgaaga
     3301 caatatggct aactctgtta ttgcccaact gcttttcttg gatgcccaag atagtacaaa
     3361 agatatttac ctttatgtca atacaccagg tggttctgtt tcagctggtt tggcaatcgt
     3421 agataccatg aactttatca aggcagatgt ccaaaccatt gttatgggaa tggctgcatc
     3481 tatgggaaca gtcatcgcat caagtggagc aaaaggcaaa cgtttcatgc ttccaaatgc
     3541 tgaatacatg attcaccaac caatgggcgg tacaggtggt ggtacccaac aaactgatat
     3601 ggctatcgct gcagaacact tgctcaaaac tcgtaatacc ttggaaaaaa tcttggctga
     3661 aaattcaggt cagtcaatgg aaaaagtcca tgcagatgca gaacgtgata actggatgag
     3721 cgcccaggaa acacttgaat atggctttat tgatgaaatt atggccaaca attcattgaa
     3781 ctaatgatga tagaaggcaa actcgactgg gtttgctttt tttggtataa tagggagaga
     3841 tttcttagaa agaggattta tcatgtttga aaaagtcaat cgctctggct tgattatcta
     3901 tctttactat aatcgtgatg ccaaaaaact gcaggattat ggagatatta cctatcattc
     3961 caagaaacat cgttacttac aactctatgt tccaactcaa gaagtggagc aattggtcgg
     4021 acgcttgagc aaggaaaaat ttattaaaaa agttagggtt tgtcatatcc aagagttgga
     4081 aacacccttt gtgggcaatc tttatcgata ggaaaacgct atcatcgaaa aagttcaagg
     4141 aaaacattga caattttctg ataattcggt atattcttaa cagactattt aagaaataag
     4201 gagacaaaaa agatgaagaa aaaatttgcc ctatcgtttg tggcgcttgc aagtgtagca
     4261 cttcttgcag cctgtggaga agtgaagtct ggagcagtca acactgctgg taactcagta
     4321 gaggaaaaga caattaaaat cgggtttaac tttgaagaat caggttcttt agctgcatac
     4381 ggaacagctg aacaaaaagg tgcccaattg gctgttgatg aaatcaatgc cgcaggtggt
     4441 atcgatggaa aacaaatcga agtagtcgat aaagataata agtctgaaac agctgaggct
     4501 gcttcagtta caactaacct tgtaacccaa tctaaagtat cagcagtcgt aggacctgcg
     4561 acatctggtg cgactgcagc tgcggtagcg aacgctacaa aagcaggtgt tccattgatc
     4621 tcaccaagtg cgactcaaga tggattgact aaaggtcaag attacctctt tattggaact
     4681 ttccaagata gcttccaagg aaaaattatc tcaaactatg tttctgaaaa attaaatgct
     4741 aagaaagttg ttctttacac tgacaatgcc agtgactatg ctaaagggat tgccaaatct
     4801 ttccgcgagt catacaaggg tgaaatcgtt gcagatgaaa ctttcgtagc aggtgacaca
     4861 gacttccaag cagcccttac aaaaatgaaa gggaaagact ttgatgctat cgttgttcct
     4921 ggttactata atgaggctgg taagattgta aaccaagcgc gtggtatggg aattgacaaa
     4981 ccaatcgttg gtggtgatgg attcaacggt gaggagtttg tacaacaagc aactgctgaa
     5041 aaagcatcaa acatctactt tatctcaggc ttctcaacta ctgtagaagt ttcagctaaa
     5101 gctaaagcct tccttgacgc ttaccgtgct aagtacaatg aagagccttc aacatttgca
     5161 gccttggctt atgattcagt tcaccttgta gcaaacgcag caaaaggtgc taaaaattca
     5221 ggtgaaatca agaataacct tgctaaaaca aaagattttg aaggtgtaac tggtcaaaca
     5281 agcttcgatg cagaccacaa cacagtcaaa actgcttaca tgatgaccat gaacaatggt
     5341 aaagttgaag cagcagaagt tgtaaaacca taatagaaaa atgttgaaat agggaatgag
     5401 cctttgactc actccctgtt tcgatattta atactcttcg aaaatctctt caaactgcgt
     5461 caacgtcgcc ttggattata tatgtgactg acttcgtcag tcttatctac aacctcaaag
     5521 cagtgctttg agcaacctgc ggctagtttc ctagtttgct ctttgatttt cattgagtat
     5581 aagaacctat caaaaagtga gggaaacccc tcggaattat aaatagaaag agtgaatctt
     5641 atgctccaac aactcgtaaa tggtttgatt ctaggtagtg tttacgcgct gttagcccta
     5701 ggatatacca tggtttacgg aattatcaag ctcatcaact tcgcccatgg tgatatttat
     5761 atgatgggag cctttatcgg ttatttcttg atcaattctt tccaaatgaa tttctttgta
     5821 gcgcttattg tagctatgct agcgacagct attcttggtg tcgtgattga gtttcttgct
     5881 taccgacctt tgcgccactc tactcgtatt gctgttttga ttacggctat tggggtttct
     5941 ttcctattgg agtatggaat ggtctatctg gttggtgcca atacccgtgc cttccctcaa
     6001 gcgattcaaa cagttcgata tgatttggga ccaattagct taacaaatgt gcagttaatg
     6061 attttggcca tttccttgat tttgatgatt ttgttacaag tcattgtcca aaagactaag
     6121 atggggaaag ccatgcgtgc agtatcagta gatagcgacg cggcacaatt gatggggatc
     6181 aatgtaaacc gtacgattag ctttaccttc gctttgggtt ctgctcttgc gggtgcggct
     6241 ggtgttctga ttgctcttta ttataactct cttgagcctt tgatgggggt tactccaggt
     6301 cttaaatctt tcgttgccgc agtacttggt ggtatcggaa ttattcctgg tgcggctctt
     6361 ggtggctttg tgattggtct attggaaacc tttgcgacag cctttgggat gtcagatttc
     6421 cgtgatgcca ttgtttatgg aatcttgttg ttgatcttga ttgtccgccc agctggtatc
     6481 cttggtaaga atgtgaaaga gaaggtgtaa acgatgaagg aaaatttaaa agttaatatt
     6541 ctatggttac tccttttgtt agctggctat agcttgatta gtgtactggt ttcagtcgga
     6601 gtacttaatc tattctatgt acagatttta caacaaattg gaattaatat tattttggct
     6661 gttggtctca acttaatcgt tggtttttca ggacaatttt cacttggtca tgctggtttc
     6721 atggcaattg gtgcctatgc agcagctatt attggttcta aatcaccaac ctacggtgcc
     6781 ttctttggag ctatgcttgt aggggctttg ctttcaggag cagttgcctt acttgtcggc
     6841 attccaacct tgcgcttgaa gggggactat cttgcggtag caactctagg tgtttctgaa
     6901 attatccgta tctttatcat caatggtgga agccttacaa atggtgcggc aggtatctta
     6961 gggattccta actttacaac ttggcaaatg gtttacttct ttgtcgtgat tacaaccatt
     7021 gcaaccttga acttcttgcg tagcccaatt ggtcgttcaa ccctctctgt tcgtgaagat
     7081 gaaatcgctg ctgagtcagt tggggttaat acgactaaaa ttaaaatcat cgcttttgtc
     7141 tttggtgcca ttactgcaag tattgctggg tcacttcagg caggatttat cgggtctgtt
     7201 gtaccgaaag attacacctt catcaactca atcaacgttt tgattattgt tgtatttggt
     7261 ggactcggtt ccattacagg tgcgattgtt tcggctattg ttctgggaat tttgaatatg
     7321 cttctccaag atgttgctag tgtgcgtatg attatttacg ctttggcctt ggtattggta
     7381 atgattttca gaccaggtgg actccttgga acatgggaac tgagcctatc acgtttcttt
     7441 aaaaaatcta agaaggagga acaaaactaa tggcattact tgaagtaaaa cagttaacca
     7501 aacattttgg tggtctaaca gctgttggag atgtgactct tgaattgaac gaaggggaac
     7561 tggttggatt aatcggtcca aacggagctg ggaaaaccac ccttttcaac cttttgaccg
     7621 gtgtttatga accaagtgag ggaacagtaa ccctagatgg tcaccttttg aatgggaaat
     7681 caccttataa gattgcctct ttgggacttg gacgtacttt ccaaaatatc cgtcttttta
     7741 aagatttaac agttttagac aatgttttga ttgcttttgg aaaccatcac aaacagcatg
     7801 tttttactag tttcttacgc ttaccagctt tttacaagag tgaaaaagaa ttaaaggcta
     7861 aagctttgga attgttgaaa atctttgatt tagatggtga tgcagagact cttgctaaaa
     7921 atctttccta cggacaacaa cgtcgtttgg aaattgttcg tgcccttgct acggaaccta
     7981 aaattctctt cttagatgaa ccagcagcag gtatgaaccc acaggaaaca gccgaattga
     8041 ctgagttaat tcgtcgtatc aaagatgaat ttaagattac aatcatgttg attgaacacg
     8101 atatgaatct ggtcatggaa gtaacagaac gtatctacgt acttgaatat ggccgtttaa
     8161 ttgctcaagg aactccagac gaaattaaga ccaataaacg cgttatcgaa gcttatctag
     8221 gaggtgaagc ctaatgtcta tgttaaaagt tgaaaatctt tctgtgcatt acggtatgat
     8281 ccaagcagtc cgtgatgtaa gctttgaagt taatgaagga gaagttgttt cccttatcgg
     8341 tgccaacggt gcaggtaaga caactattct tcgcaccttg tcaggtttgg ttcgaccaag
     8401 ttcaggaaag attgaatttt taggtcaaga aatccaaaaa ataccagctc agaaaatcgt
     8461 ggcaggtggt ctttcacaag ttccagaagg acgccacgtc tttcctggct tgactgttat
     8521 ggaaaatctt gaaatgggag ctttcttaaa gaaaaatcgt gaagaaaatc aagctaactt
     8581 gaagaaggtt ttctcacgct ttcctcgtct tgaagaacgg aagaaccaag atgcagctac
     8641 tctttcagga ggggaacaac aaatgcttgc catgggacgc gctcttatgt caacaccaaa
     8701 acttcttctt ttagatgaac catcaatggg acttgccccg atcttcatcc aagagatttt
     8761 tgatatcatt caagatattc agaagcaagg aacaaccgtc ctcttgattg aacaaaatgc
     8821 caataaagca cttgcaatct ctgaccgagg atatgtattg gaaacaggaa aaatcgtcct
     8881 atcaggaaca ggaaaagaac tcgcttcatc agaagaagtc agaaaagcat atctaggtgg
     8941 ctaaaacaat ccagtggatt gttttagtcg gcagatgaag attacgaagt aatcatcaat
     9001 atagtccggg ggaccttttt agtcggtaaa ttgagattgc aaacaaatat gcatctacat
     9061 tgaaagctta atttctaata attgaaaaaa tcgaatgaaa agtttcttac cttcattcac
     9121 agagctcgat ttcagagctc tttttgctag cttattcata cttttctgaa tttcgaaaaa
     9181 gaaatgtaag cgtttgatag atttacaaaa agattgtata atagggataa gaatagaaaa
     9241 ggagaagtct catggcagtt aaagatttta tgacccgcaa ggtagtttat attagtccag
     9301 atacaacagt atctcatgca gcagatttga tgagagagca aggtttgcac cgtctgcctg
     9361 ttatcgaaaa tgatcaatta gttggtttgg tgactgaggg aaccattgca caagcaagtc
     9421 catctaaagc aacaagtctt tctatctatg agatgaatta tcttctgaat aagacaaaag
     9481 taaaagatgt catgattcgc gatgttgtca ctgtctcagg ctatgctagt ctagaagatg
     9541 caacttatct gatgttgaaa aataagatta gtattctccc tgtcgtagat aaccatcaag
     9601 tatacggagt tattactgac cgtgacgttt tccaagcctt tcttgaaatt gcaggttatg
     9661 gcgaagaagg gattcgtgta cgctttgtta cagaagatga agttggtgtt cttggaaaaa
     9721 ttgtttcttt gattgtagaa gaaaatttga atatctccca tacagtcaat attccgcgta
     9781 aggatggtaa ggtgattatc gaagtgcaaa tcgatggatc aattgattta ccagccttga
     9841 aagaaaaatt tgaagcaaat ggtattcaag tggaagaaat cgctcgcact tcagcaaaag
     9901 tcttgtaaga agggaagccc aaaggcttct tttttcatga aaaggggatt agagaaaaag
     9961 atggaaagaa atgataaaat atgctataat gaaataatgt aaaaaaggag tatttatgga
    10021 catttcagta attcgtcaga aaattgacgc aaatcgtgaa aaattagctt ctttcagggg
    10081 gtctctttga cctcgaaggg ctagaggaag agattgccat cttggaaaac aagatgacag
    10141 aacctgattt ttggaacgat aatattgcag cccaaaaaac gtcgcaagaa ttaaatgaat
    10201 taaaaaacac ttacaatacc ttccataaga tggaagagtt gcaggatgaa gtcgaaattt
    10261 tattggattt tttggctgaa gacgagtcag tgcatgatga actggtagcg cagttagccg
    10321 aacttgataa gataatgacc agctacgaga tgactctact cttgtcagaa ccttatgacc
    10381 acaacaatgc catcttggaa atccatccag gttctggtgg tactgaggcg caggactggg
    10441 gtgatatgtt gcttcgtatg tatactcgtt atggtaatgc taaaggcttt aaagtggaag
    10501 tgttggatta ccaagcaggt gatgaggctg gtattaagtc ggtaacttta tcatttgaag
    10561 ggcctaatgc ctatggtctc ctcaagtcag aaatgggtgt tcaccgctta gtgcgaatct
    10621 caccatttga ctctgccaaa cgtcgccata cctctttcac atctgtagaa gtgatgccag
    10681 aattggatga tactattgaa gtggaaatcc gtgaagatga tatcaagatg gataccttcc
    10741 gttcaggtgg tgccggtgga caaaacgtca ataaggtttc aacaggtgta cgtttaaccc
    10801 acattccaac tggaattgtt gtccaatcaa cagtggatcg tacccagtat ggaaatagag
    10861 atcgtgccat gaagatgttg caggctaagc tctatcaaat ggagcaagag aagaaggctg
    10921 cagaggtaga ttctctcaaa ggtgagaaaa aggagatcac ttggggaagc caaatccgtt
    10981 cttatgtctt cacgccttat actatggtaa aagatcaccg aactagcttt gaggttgctc
    11041 aggtagataa ggttatggat ggggacttag atggttttat cgatgcttat ctcaagtggc
    11101 gaattagcta agatagaaag gaactcacat gtcaattatt gaaatgagag atgtcgttaa
    11161 aaaatacgac aacggaacga ctgctctacg cggtgtttcg gttagcgttc aaccggggga
    11221 atttgcttac atcgtaggac cttcaggagc agggaagtca acttttattc gttctctgta
    11281 tcgtgaagta aaaatcgata aaggaagcct atcagttgct ggttttaatc tggttaagat
    11341 caaaaagaaa gatatcccgc ttctacgtcg tagtgttggg gttgtcttcc aggattataa
    11401 attgttacca aagaaaactg tctatgaaaa tattgcttac gctatggaag taatcgggga
    11461 aaatcgccgt aatatcaaaa gacgagtgat ggaagttttg gacttggttg gattgaagca
    11521 taaggttcgt tctttcccaa atgaactctc aggtggggag caacagcgga ttgcgattgc
    11581 gcgtgcaatt gtaaataatc ccaaagtatt gatagctgat gagccaacag gaaatctgga
    11641 tccggataat tcatgggaaa ttatgaatct tttggaacgg attaacctac aaggaacaac
    11701 tattttgatg gcgactcata atagccagat tgtaaatacc ttgcgccacc gtgtcattgc
    11761 cattgaaaat ggccgtgtcg ttcgtgacga atcaaaagga gagtatggat acgatgatta
    11821 gtagattttt tcgccattta tttgaagcct taaaaagttt gaaacgaaat ggttggatga
    11881 cagtagctgc tgtcagttca gtcatgatta ctttgacctt ggtggcaata tttgcatctg
    11941 ttattttcaa tacagcgaaa ctagctacag atattgaaaa taatgtccgt gtagtagttt
    12001 atatccgaaa ggatgtggaa gataatagtc agacaattga aaaagaaggt caaactgtta
    12061 caaataatga ctaccacaag gtatatgatt ctttgaagaa catgtctacg gttaaaagtg
    12121 ttaccttttc aagtaaagaa gaacaatatg aaaaattaac cgagataatg ggagataact
    12181 ggaaaatctt tgaaggagat gccaatcctc tctatgatgc ctatattgta gaggcaaaca
    12241 ctccaaatga tgtaaaaact atagccgaag atgctaaaaa aattgaaggt gtctctgagg
    12301 ttcaagatgg cggtgccaat acagaaagac tcttcaagtt agcttcattt atccgtgttt
    12361 ggggactagg gattgctgct ttgttaattt ttatcgcagt tttcttgatt tcaaatacca
    12421 ttcgtattac cattatttcc cgcagtcgcg aaattcaaat catgcgcttg gtcggagcta
    12481 aaaacagtta tatccgtgga ccgttcttgt tagaaggagc ctttatcggt ttattgggag
    12541 ctatcgcacc atctgttttg gtctttattg tttatcaaat tgtttaccaa tctgtcaaca
    12601 aatcgttggt agggcaaaat ctatccatga ttagtccaga tttatttagt ccgttgatga
    12661 ttgccctact atttgtgatt ggggttttca ttggttcatt gggatcagga atatccatgc
    12721 gccgattctt gaaggtttag gtaaaatagc tgcttttatg aggagattgt aaaatctcct
    12781 tttttgctac aagagttttt gaaaagagat gcgcagaaga aaagagcttc caaagaagtc
    12841 ccccagagaa gacttcttga tggctaattt gaacttgaaa tttggcgcac tagaaatttt
    12901 ttagaaaaaa gtgtaatttt tttataaaag cctttacaaa aaaaattaaa gtggtataat
    12961 taaatcatag aaagtgcaaa cgttttcgta aaacgtttgc ctaaataaaa ataaaggaga
    13021 tttgaatgat gaaagataca ttcaaaaatg tcttgtcttt cgaattttgg caaaaattcg
    13081 gtaaggcttt gatggtagtt atcgcggtta tgccggctgc tggtttgatg atttcaatcg
    13141 gtaagtctat cgtgatgatt aacccaacct ttgcaccact tgtcatcaca ggtggaattc
    13201 ttgagcaaat cggttggggg gttatcggta accttcacat tttgtttgcc ctagccattg
    13261 gaggaagctg ggctaaagaa cgtgctggtg gtgctttcgc cgctggtctt gccttcatct
    13321 tgattaaccg tatcactggt acaatctttg gtgtatcagg cgatatgttg aaaaatccag
    13381 atgctatggt aactactttc tttggtggtt caatcaaagt tgctgattac tttatcagtg
    13441 ttcttgaagc tccagccttg aacatggggg tattcgtagg gattatctca ggttttgtag
    13501 gggcaactgc ttacaacaaa tactacaact tccgtaaact tcctgatgca ctttcattct
    13561 tcaacgggaa acgtttcgta ccatttgtag ttattcttcg ttcagcaatc gctgcaattc
    13621 tacttgctgc tttctggcca gtagttcaaa caggtatcaa taacttcggt atctggattg
    13681 ccaactcaca agaaactgct ccaattcttg caccattctt gtatggtact ttggaacgtt
    13741 tgctcttgcc atttggtctt caccacatgt tgactatccc aatgaactac acagctcttg
    13801 gtggtactta tgacatttta actggtgcag ctaaaggtac tcaagtattc ggtcaagacc
    13861 cactatggct tgcatgggta acagaccttg taaaccttaa aggtactgat gctagtcaat
    13921 atcaacactt gttagataca gtacatccag ctcgtttcaa agttggacaa atgatcggtt
    13981 cattcggtat cttgatgggt gtgattgttg ctatctaccg taatgttgat gctgacaaga
    14041 aacataaata caaaggtatg atgattgcaa cagctcttgc aacattcttg acaggggtta
    14101 ctgaaccaat cgaatacatg ttcatgttca tcgcaacacc tatgtatctt gtttactcac
    14161 ttgttcaagg tgctgccttc gctatggctg acgtcgtaaa cctacgtatg cactcattcg
    14221 gttcaatcga gttcttgact cgtacaccta ttgcaatcag tgctggtatt ggtatggata
    14281 tcgttaactt cgtttgggta actgttctct ttgctgtaat catgtacttt atcgcaaact
    14341 tcatgattca aaaattcaac tacgcaactc cagggcgcaa cggaaactac gaaactgctg
    14401 aaggttcaga agaaaccagc agcgaagtga aagttgcagc aggctctcaa gctgtaaaca
    14461 ttatcaacct tcttggtgga cgtgtaaaca tcgttgatgt tgatgcatgt atgactcgtc
    14521 ttcgtgtaac tgttaaagat gcagataaag taggaaatgc agagcaatgg aaagcagaag
    14581 gagctatggg tcttgtgatg aaaggacaag gggttcaagc tatctacggt ccaaaagctg
    14641 acattttgaa atctgatatc caagatatcc ttgattcagg tgaaatcatt cctgaaactc
    14701 ttccaagcca aatgactgaa gcacaacaaa acactgttca cttcaaagat cttactgagg
    14761 aagtttactc agtagcagac ggtcaagttg ttgctttgga acaagtaaag gatccagtat
    14821 ttgctcaaaa aatgatgggt gatggatttg cagtagaacc tgcaaatgga aacattgtat
    14881 ctccagtttc aggtactgtg tcaagcatct tcccaacaaa acatgctttt ggtattgtga
    14941 cggaagcagg tcttgaagta ttggttcaca ttggtttgga cacagtaagt cttgaaggta
    15001 aaccatttac agttcatgtt gctgaaggac aaaaagttgc agcaggagat ctccttgtca
    15061 cagctgactt ggatgctatc cgtgcagcag gacgtgaaac ttcaacagta gttgtcttca
    15121 caaatggtga tgcaattaaa tcagttaaat tagaaaaaac aggttctctt gcagctaaaa
    15181 cagcagttgc taaagtagaa ttgtaatata cttgaggttg gaagctgtat tccaacctct
    15241 tattttggga gaaaagaatg aaatttttaa cactcaatac tcacagttgg atggagaaag
    15301 aagcagagga aaaattccag attttgcttg aagatattct tgaaaaggac tatgatttga
    15361 tttgtttcca agaaatcaat caggagatga cctcgtcaga ggtggaggtt aatgaccttt
    15421 atcaagcttt gccagcagct gagcctattc accaagacca ttatgttaga ctcttggttg
    15481 aaaagttgtt agagcaaggg aaaaattact actggacctg ggcttataac catatcggct
    15541 atgaccgcta ccacgaaggt gtggctatct tgtctaaaac acctattgaa gccagagaaa
    15601 ttttggtttc agatgtggat gatccaacag actatcatac tcgccgtgtt gccctagctg
    15661 aaactgtagt cgatggcaag gagctagcag ttgccagtgt tcatctctct tggtgggata
    15721 aaggtttcca agaagaatgg gcacgatttg aggctgtctt gaaaaaattg aacaagccac
    15781 ttttactagc tggagatttt aacaacccag caggtcagga aggttaccaa gctattttag
    15841 ctagtccatt aggcttacaa gacgcatttg aagttgctca agagaaaagt ggtagctata
    15901 ctgttccgcc tgaaattgat ggctggaaag ggaacactga accccttcga atcgattatg
    15961 tctttactac caaagagtta gcggtggaaa atttacatgt cgtatttgat ggtaacaaga
    16021 gtccacaagt gagtgatcac tatggcttga atgctatatt aaactggaaa taataactga
    16081 aaagaggttg gaactataaa attccagcct tttcttacta gagaagctac tggaaatagc
    16141 ctaaataagt gagactactg taatggaata aaatatggta taattgataa ggtagataga
    16201 atcgaggatg ttatgtcatt tacgaaattt caatttaaaa actatattag agaagccttg
    16261 aaggagttaa aatttacaac tccaacagag gtgcaagaca agttgattcc tattgttttg
    16321 gcaggtcgtg acctagtagg agaatcaaaa acaggttcag gtaagactca tactttcttg
    16381 ttaccgattt tccagcaatt agatgaagct agcgatagtg tacaagcagt gattactgca
    16441 ccgagtcgtg agttggctac tcaaatttac caagtagcgc gtcagatttc agctcactca
    16501 gatgtcgaag ttcgtgtggt taattatgtg ggtggtacgg ataaggctcg ccagattgag
    16561 aaattggaaa gcaatcagcc tcatattgtt attggaacac caggccgtat ctacgacttg
    16621 gttaaatctg gtgatttagc tattcataaa gccaagacat ttgttgttga tgaagcagat
    16681 atgaccttgg atatgggatt cttggaaact gttgataaga ttgctggcag tcttccaaaa
    16741 gacttgcaat tcatggtctt ctcagcgact atcccacaaa aactgcaacc attcttgaaa
    16801 aaatacttat caaatcctgt tatggagaaa attaagacca aaacggttat ttctgacacc
    16861 attgataatt ggttgatttc gaccaaggga catgataaga atgctcaaat ttaccagttg
    16921 actcagttga tgcagccgta tttggcaatg atttttgtta acactaaaac gcgtgctgat
    16981 gaattgcatt catatctgac tgctcaaggc ttgaaggttg caaaaatcca tggagatatt
    17041 gcccctcgtg aacgcaagcg aatcatgaat caggtgcaaa atctggattt tgagtatatt
    17101 gtcgcaacag atttagcagc gcgtgggatt gacattgaag gtgtcagcca tgtcatcaat
    17161 gatgccattc cgcaagactt atcttttttt gttcatcgtg ttggtcgtac tggacgaaat
    17221 ggcctaccag gtacagctat taccctttat cagccaagtg atgactcgga tatccgtgag
    17281 ttggagaaat tgggaatcaa gtttagtcct aagatggtca aagacgggga atttcaagat
    17341 acctatgacc gtgatcgtcg tgccaaccgt gagaaaaaac aagataaact tgatatcgaa
    17401 atgattggtt tggttaaaaa gaaaaagaaa aaagtcaaac cgggttataa gaagaaaatt
    17461 caatgggcgg ttgatgaaaa gcgccgtaaa accaagcgtg ctgaaaatcg cgctcgcggt
    17521 cgtgcagagc gtaaagctaa acgccaaaca ttttaataga aattgttgga gtattgagct
    17581 ccaacttttt tatttatgag aacgaactat ctaaaccgaa acactacatt aaagactgca
    17641 aattgcgatt aaaaatggta taatgataaa gttatatagt cccgataaga tggtaggtat
    17701 ttattacgaa gagttttcct atcagtactt tgtaactcta taacaatatt ttttaagggg
    17761 ggacattttt atgtcagaac gtaaattatt cacgtctgaa tctgtatctg aggggcatcc
    17821 ggataagatt gcagaccaaa tttcagatgc gattttggat gctattttag caaaggatcc
    17881 agaggcgcac gttgctgctg aaacagctgt atatactggt tctgtccacg tttttggtga
    17941 aatttctaca aatgcctatg tggatattaa ccgtgtggtt cgtgatacca ttgcagagat
    18001 tggttatacc aatacagaat atggattttc tgctgagacg gtgggagtac acccatcttt
    18061 ggtggaacaa tctcctgaca tcgctcaagg tgttaacgaa gccttggagg ttcgtggaaa
    18121 tgctgatcaa gatccactgg acttgattgg agcaggtgac caagggctca tgtttggatt
    18181 tgcagtagat gaaacagaag agctcatgcc attgccaatt gcactcagtc ataaattggt
    18241 tcgtcgtctg gcagaacttc gtaagtctgg agaaattagc tatctccgtc cagatgcaaa
    18301 atcacaagtt acagttgagt acgatgaaaa tgaccgtccg gtacgtgtag atacagtcgt
    18361 tatttctact cagcatgatc cagaggccac taatgaacaa atccatcaag atgtgattaa
    18421 caaggtcatc aaagaagtta ttccatcttc ttatcttgat gataagacaa aattctttat
    18481 caatccgaca ggtcgttttg taatcggtgg tcctcaaggg gactcaggtt tgactggtcg
    18541 taagattatt gtagatactt atggtggcta ctctcgtcat ggtggtggtg ccttctctgg
    18601 taaagatgcg actaaggtgg atcgttcagc ctcttatgcg gctcgctata ttgccaagaa
    18661 tatcgttgca gcaggccttg ctaagaaggc agaagtgcag ttggcctatg ctatcggtgt
    18721 tgcgcaacct gtttctgttc gtatcgatac tttcggtaca ggaacagtag ctgaaagtca
    18781 acttgaaaaa gcggctcgtc aaatctttga ccttcgccct gcagggatta tccaaatgct
    18841 ggacctcaag cgtccaattt accgtcaaac atcggcttac ggtcacatgg gacgtacaga
    18901 tattgatctt ccatgggaac gtttggataa ggtagatgct ttgaaagaag cagtaaaata
    18961 agattttaag aggggaacgt cctctctttt ttatagtttt taactatact gggatactgt
    19021 tctgaaaatc cattttgcga aagtagagat ttacatgtat agtagattga aactagaata
    19081 gtacacctca acttctaaaa cattgttagc aatcaatttg actgtcctga tcgatttctc
    19141 ctgttcttgt ttcattttac tatatttctt taaaaatgat aaaggttgag atttctcctc
    19201 gtaatagata atcatgggga tatttcaatc caaagtttta ttcgttatca cttgactatt
    19261 gcaaggtttt ctagagcaac agagtcatgg aatggactca tggttgagat ttctccttgt
    19321 tgcttggact tcattcaaaa gtctgttacc caagccttgt tcaaacttcc aatacactag
    19381 ctgttttcat agcatgactt ctgtactaga ctttcttttc cgaataaata gatagaacca
    19441 cagaatctag taaacctaga attaaaatta tggtataata ttagcaataa aagaaatctg
    19501 gaggattaga atcatggtat caacgaaaac acaaattgct ggttttgagt ttgacaattg
    19561 cttgatgaat gcagcaggtg tggcttgtat gacgatagag gagttagaag aggtcaaaaa
    19621 ctcagcggca ggaacctttg ttactaagac agcgaccttg gacttccgtc aggggaatcc
    19681 tgagccacgc taccaagatg ttccacttgg ttccatcaac tctatgggct tgccaaataa
    19741 tggcttagac tattatttgg attatctttt agatttgcag gaaaaagagt cgaaccgaac
    19801 tttcttctta tctctggtcg gcatgtctcc agaggaaacc catactattt tgaaaaaagt
    19861 tcaagagagt gattttcgtg gtctgactga gctaaatctt tcctgtccaa atgttccagg
    19921 taaacctcag attgcctatg attttgagac aacagaccgg attttggcag aagtgtttgc
    19981 ttacttcacc aaacctcttg gaattaaatt gccaccttat tttgatattg ttcactttga
    20041 tcaagcggca gctattttca acaaatatcc gctcaagttt gtcaactgcg ttaactctat
    20101 cggaaacggc ctctatatag aagacgaatc tgtcgttatt cggcctaaga atggttttgg
    20161 tggaattggt ggagaataca tcaaaccgac tgctctagcc aatgttcacg ccttttatca
    20221 acgtttaaat cctcaaatcc aaattatcgg aacaggtggc gttctgactg gtcgagatgc
    20281 ctttgaacac atcctctgtg gagcaagtat ggtgcaggtg ggaacgaccc ttcacaaaga
    20341 aggcgtcagt gcttttgacc gcattaccaa tgaactgaaa gcaatcatgg tggaaaaagg
    20401 ctacgagagc ttagaagatt tccgtgggaa attgcgctat attgactaaa ttaaatcgaa
    20461 aaatctgaag aaaggagaga cgatgctagc cattgaagaa agtcagaagt tgactttatc
    20521 aaatttaccg agcctgagcc tatttacagg gacagatcag ggtcagtttg aagtgatgaa
    20581 gagtcaagtg ttgaaacaga ttgggtatga ttctgctgac ctcaactttg cctactttga
    20641 tatgaaagaa gtagtttaca aggatgtgga actggagttg gtcagccttc ctttctttgc
    20701 ggatgagaaa atcgtgatat tagattattt tatggatatc acgactgcta agaaacgctt
    20761 tttgacagat gatgagctta agtcatttga ggaatacctt gacaatcctt ctccaacaac
    20821 caagttgata atctttgcag aaggaaagct ggatagcaaa agacggttag tcaaattact
    20881 taagcgtgat gccaaggcct tcgatgcagt agaagtaaaa gaacaagaat tgcgccagta
    20941 tttccaaaag tggagtcaga aacaaggtct gcagtttacc aatcattctt ttgaaaatct
    21001 cctcatcaag tcggggtttc aatttagcga aatccagaaa aatcttctct ttttacagtc
    21061 ctataaggcg gattctgtta tcgaggaaga ggatattgtt aacgcaattc ccaagacctt
    21121 gcaggacaat atttttgatt taactcagtt tattctgact aaaaagatgg atcaggcgcg
    21181 cgatttggtg agagacttga ccttgcaagg ggaagatgaa atcaaactaa ttgcagtcat
    21241 gctgggacaa tttcggactt ttactcaggt gaagattttg gcggagtctg gccaaacaga
    21301 atcgcagatt gcaagtagtt taggtagtta tctgggacgt aacccaaatc cttatcaaat
    21361 caagtttgca ttaagagatt cgagaggact ttctttgagc tttctgaagc aagctatttc
    21421 ctatttgatt gagacagact atcagattaa gacaggtctt tatgaaaaag gtttcctttt
    21481 tgaaaaggca ctcttacaga ttgctagtca ggtcaattga catttgttga aactacaacc
    21541 cgcgtcagga ttatcttgtc gtgggtttct tgctgatttg cttatctata agcaaaaaac
    21601 ttgaaaaaag tgaatgtttg cgttatcatt ttcatataga aagaaaaaga ggtattacag
    21661 atggctatta tcttaccaga acttccatat gcatacgacg ctttggaacc atacatcgat
    21721 gcggaaacaa tgcatttgca ccatgacaaa caccatcaaa cttatgtcaa caatgccaat
    21781 gcagctttag aaaaacaccc tgaaatcggt gaagaccttg aagccttgct tgctgatgta
    21841 gaatctatcc cagctgatat ccgtcaagca cttatcaaca atggtggcgg acacttgaac
    21901 cacgctcttt tctgggaatt gatgactccc gagaaaacag ctccttcagc agaactggca
    21961 gcagcaatcg atgcaacatt tggttcattt gaagaattcc aagcagcctt cactgcagca
    22021 gcaacaactc gttttggttc aggttgggca tggttggttg tcaacaaaga agggaaactt
    22081 gaagtgactt caacagcaaa ccaagacaca ccaatctcag aaggtaaaaa accaatcttg
    22141 ggcttggacg tttgggaaca tgcttactac gtgaaatacc gcaacgtgcg tcctgactac
    22201 atcaaagctt tcttttcagt aatcaactgg aataaagtag atgaattgta cgcagctgct
    22261 aaataatgat agttggaggg aagaattgtt cttctctttt ttaggttata agattctggt
    22321 ctgacaaaat cgttagactt ttttcatttt ttatgagaaa cgtgctaact gctagaaatt
    22381 atggtagaat aaagtattaa gtaatcgtgg aaaaaggata tctatgcgaa aagaaattgc
    22441 acctgaatta tacaactata acaagtttcc tggtccggag ttccatttac acggggacaa
    22501 ggtcgaaacg gaagggatag ctttttcctt ggttgaaaat atcaaggatg cctttgatgt
    22561 gacgactttt aatcagcgtt tttcagaagt cttaaccaag tttgattata tcgtggggga
    22621 ctggagcaac gaacagcttc gcctacgagg tttttacaag gatgaccgaa cagaagaaaa
    22681 acttgaaaaa atcagtcgtt tacaagacta ccttttagag tattgtagtt atggttgtgc
    22741 ctattttgtc ttagaaaatg aagcccctaa gcgagcatca tttgacaaga aaatgcgtaa
    22801 gacggaagaa gaaacacctt ctagaaaagg aaagaaaccg actcaaacta aacgaaagtc
    22861 gaatgcagat aagaaaaata gacgtcgtca gaaagaccag cattctcaga aagaggacaa
    22921 ggaacaacgt cattttgtca ttcgtcagaa gtgagtagag aataaggaga agaaatgaaa
    22981 ccctcaattc atagtttggt acatcaaacc atgcaggaat gggtattgga gcagggagaa
    23041 aagaaattcc gtgcagatca aatctgggaa tggctctacc gtaaacgtgt gcagtcattt
    23101 gaagaaatga ccaacctttc caaggatttg attgctaagc tcaatgacca gtttgtggtc
    23161 aatcccttga aacaacgtat tgtgcaagag tctgctgatg gtacagtcaa atatctcttt
    23221 gaattgcctg acggtatgtt aattgagact gtactcatgc gtcaacacta tggtttatct
    23281 gtctgtgtga ccactcaggt cggctgtaat atcggttgta ccttctgtgc ctctggtttg
    23341 attaagaagc agcgtgacct caataacggt gaaatcgtag cgcaaatcat gctggttcag
    23401 aaatactttg ctgatgaagg ggttcaggtc aatcttgccg tgtctcttca cgcacccaac
    23461 aatgaacttc gttcaagtac catgaagatt aaccgtgcct ttccgattga aaaactcttt
    23521 gctgctattg aatactacat tgagacaaca aaccgtcgtg taacctttga atatatcatg
    23581 cttaatgaag tcaacgacgg tgtagaacaa gccttggaat tggctgaatt gctcaagaac
    23641 atcaagaaat tgtcttatgt aaacttgatt ccttataacc cagttagtga gcatgaccaa
    23701 tatagccgta gtcccaaaga gcgcgtgttg gctttctatg atacgcttaa gaaaaaaggg
    23761 gtcaactgtg tggttcgtca agagcatggt acagatattg acgcagcttg tggacaattg
    23821 cgctctaaca caatgaaacg tgaccgccag aaggcagtcg cagcggtaaa tccttaatga
    23881 tgaagaagac ttataatcat attttggtct ggggagtcat tttctatagc atttgcattg
    23941 tctgtttttg ctttactcct caagaacaat ctaccgtggg agtgggaact ccaggtattc
    24001 agcatcttgg acgcctggtt tttcttttga ctcctttcaa ttctctctgg aaactgggcg
    24061 aagtgagtga cattggacaa ttatgttgga tttttttaca aaatgtcctc aatgtcttct
    24121 tgttttttcc tctgattttc caactccttt atctatttcc aaatttgcgg aaaacaaaaa
    24181 aggtccttct ttttagtttt cttgtgagtc ttggaatcga gtgtacgcaa ttaatcttgg
    24241 actttttctt tgatttcaat cgcgtctttg agattgatga tttgtggacc aatactttgg
    24301 gtggctatct ggcttggctc ctttataaac gattacataa aaacaagata aggaattaaa
    24361 atgagtattt tagaagttaa aaatctgagt cacggttttg gtgaccgtgc aatttttgaa
    24421 gatgtgtcct tccgtctcct caagggagaa catatcggcc tggtcggtgc caatggtgaa
    24481 ggaaaatcaa cctttatgag tatcgtgact ggtaaaatgc tgccagatga aggaaaggtt
    24541 gagtggtcca aatatgtgac ggctggttac ttggatcagc actctgtcct tgctgaaaga
    24601 cagtcggtgc gtgatgttct ccgtacggct tttgatgagc ttttcaaagc tgaagctcgt
    24661 atcaatgacc tctatatgaa aatggctgaa gacggcgcgg atgttgatgc tctcatggaa
    24721 gaagtaggag aacttcaaga ccgtctggag agtcgtgatt tctatacctt ggatgctaag
    24781 attgacgaag tagcgcgtgc tcttggtgtt atggactttg gcatggatac ggatgtaact
    24841 tctttgtcag gtgggcaaag aaccaaggtg cttttggcaa aacttctcct tgaaaagcct
    24901 gatatcttgc tgttggacga gccgaccaac tacttggatg ctgagcatat tgattggctc
    24961 aagcgctatc tccaaaacta tgagaatgcc tttgttctca tttcgcacga tattccattc
    25021 ctcaatgacg ttattaatat tgtctatcat gtggaaaatc aacagctgac gcgttactct
    25081 ggtgactact accagttcca agaagtttat gctatgaaga aatctcagct agaggcagcc
    25141 tacgaacgcc agcagaaaga gattgcagac ctcaaggact ttgtggctcg taataaagcc
    25201 cgtgttgcaa ctcgtaatat ggctatgtct cgtcaaaaga aattggataa gatggatatt
    25261 atcgaactcc aaagtgagaa accaaaacca tcctttgatt tcaaaccagc tcgtacacca
    25321 gggcgcttta tcttccaagc caagaacttg caaattggtt acgaccgtcc tcttactaag
    25381 cctttaaatc ttaccttcga acgcaatcaa aaggttgcga ttattggtgc taatggtatt
    25441 ggaaaaacaa ctctcttgaa gagtctcttg ggcattatct cgccaatcgc tggggaagtg
    25501 gagcgtggag attatttaga acttggttat tttgagcagg aagtagaagg tggtaatcgc
    25561 caaactcctc ttgaagctgt ctggaatgcc tttcctgccc ttaatcaagc agaagtccgt
    25621 gcagcccttg cccgttgtgg tttgacaacc aaacatattg aaagccagat tcaagtatta
    25681 tcagggggag agcaagccaa ggttcgtttc tgtctcttga tgaatcgtga aaacaacgtt
    25741 ttagtgctgg acgagccgac caaccatttg gatgtggatg caaaggatga gctcaaacgc
    25801 gctctcaaag aatacagggg atctatcctt atggtctgcc acgagccaga cttttatgaa
    25861 ggttggatag accaaatatg ggattttaat aatttaactt aagaatgaga gtaaaagaaa
    25921 tacggctctt tgtcaactgt agtgggttga agtcagctaa gctcgagaaa ggacaaaatt
    25981 cgtcctttct tttttgatgt tcagagcgat aaaaatcctt tttttgaagt tttcaaagtt
    26041 ccgaaatcca aaggcgtttc gtttgataag tttgatgaga ttattggt
//
LOCUS       DAVHTH010000028        25954 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.028, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000028 DAVHTH010000000
VERSION     DAVHTH010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25954)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25954)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25954
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.028"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            82..354
                     /locus_tag="VVR63_001204"
                     /pseudo
     CDS             82..354
                     /locus_tag="VVR63_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000547411.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(465..668)
                     /locus_tag="VVR63_001205"
     CDS             complement(465..668)
                     /locus_tag="VVR63_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEU6129226.1"
                     /translation="MSVEEKLNQAKGSIKEGVGKAIGDEKMEKEGAAEKVVSKVKEVA
                     EDAKDAVEGAVEGVKNMLSGDDK"
     gene            complement(699..1307)
                     /locus_tag="VVR63_001206"
     CDS             complement(699..1307)
                     /locus_tag="VVR63_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEU6129227.1"
                     /translation="MSNEKNTNTNVEKKDATVVAHEIKGELTYEDKVIQKIIGLSLEN
                     VSGLLGIDGGFFSNLKEKIVNSDDVTSGVNVEVGKTQVAVDLNVIVEYQKNVPALYSE
                     IREIVSSEVAKMTDLEIVEINVNVVDIKTKEQHEADSVSLQDRVSDVAESTGEFTSEQ
                     FEKAKSGLGSGFSTVQEKVSEGVEAVKGAANGVVSHENTRVN"
     gene            complement(1346..1516)
                     /locus_tag="VVR63_001207"
     CDS             complement(1346..1516)
                     /locus_tag="VVR63_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HEU6129228.1"
                     /translation="MEWLKQYRYPIIAGLIGVFLACLIVSFGFFKTIFVLILGALGVA
                     AGLYIEKNYIDK"
     gene            complement(1528..2094)
                     /gene="amaP"
                     /locus_tag="VVR63_001208"
     CDS             complement(1528..2094)
                     /gene="amaP"
                     /locus_tag="VVR63_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HEU6129229.1"
                     /translation="MSKAKKICFIIFCILILTIFLPVLIDYHQVSDLGIHLLSWRQNS
                     VVEFYLARYVFWGTVVLSTLVLLSILVVMFYPKRYLEIQLETKNDTLKLKNSAIEGFV
                     RSLVSDHRLIKNPTVHVNLRKNKCFVHVEGKILPSDNIADRCQIIQNEITNGLKQFFG
                     IERQVKLEVAVKNYQPKPQNKKTVSRVK"
     gene            complement(2178..2342)
                     /locus_tag="VVR63_001209"
     CDS             complement(2178..2342)
                     /locus_tag="VVR63_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEU6129230.1"
                     /translation="MGIIANVFAGLVGAYAGQSLLGSWGPSIAGMALLPSIVGAAIVI
                     TVVSFFTGRK"
     gene            2785..4266
                     /locus_tag="VVR63_001210"
     CDS             2785..4266
                     /locus_tag="VVR63_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU6129231.1"
                     /translation="MRDLLSKKSHRQLELLELLFEHKRWFHRSELAELLNCTERAVKD
                     DLSHVKSAFPDLIFHSSTNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQ
                     AESICKEFYISSSSLYRIISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQYFSE
                     KYYFLEWPFENFSSEPLSQLLELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFME
                     VDKDSFNDQSLDFLMQAEGIEGVAQSFESEYNISLDEEVVCQLFVSYFQKMFFIDESL
                     FMKCVKKDSYVEKSYHLLSDFIDQISVKYQIEMENKDNLIWHLHNTAHLYRQELFTEF
                     ILFDQKGNTIRNFQNIFPKFVSDIKKELSHYLETLEVCSSSMMVNHLSYTFITHTKHL
                     VINLLQNQPKLKVLVMSNFDQYHAKFVAETLSYYCSNNFELEVWTELELSKESLEDSP
                     YDIIISNFIIPPIENKRLIYSNNINTVSLIYLLNAMMFIRLDE"
     gene            4628..5629
                     /locus_tag="VVR63_001211"
     CDS             4628..5629
                     /locus_tag="VVR63_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU6129232.1"
                     /translation="MVEQRKSITMKDVALEAGVSVGTVSRVINKEKGIKEVTLKKVEQ
                     AIKTLNYIPDYYARGMKKNRTETIAIIVPSIWHPFFSEFAMHVENEVYKRNNKLLLCS
                     INGTNREQDYLEMLRHNKVDGVVAITYSPIEHYLTSGIPFVSIDRTYSDIAIPCVSSD
                     NDAGGREAAKQLISKGCQHLAFVGGHNTTINETKRRRISFEKYVQEHKIPLSIFDLDE
                     TVTDYYGKLESFLEENSSIDGIFTINDFTALDVIEILEKNGKRIPHDVQIIGYDGIKM
                     AGDRDYLLSTIEQPLEEMAKEAVRILFDIIDGKTVNLQTILPVKFVEGKTTKNENKS"
     gene            5780..6697
                     /locus_tag="VVR63_001212"
     CDS             5780..6697
                     /locus_tag="VVR63_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001084977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU6129233.1"
                     /translation="MNSKAKQVSLWERIKKQKLLLLMTVPGLVLTFIFKYIPMYGVLI
                     AFKDYNPLKGILGSDWIGFSEFTKFISSPNFGILLANTLKLSIYGLLLGFLPPIILAI
                     MLNQLLSEKVKKRIQLILYAPNFISVVVIVGMIFLFFSVGGPINNFLSMFGMKADFLT
                     NPDFFRPLYIFSGIWQGMGWASTLYTATLVNVDPALVEAARLDGANIFQRIWHIDIPA
                     LKPIMVIQFVLAAGGIMNVGYEKAFLMQTSLNLPTSEIISTYVYKVGLVSGDYSYSTA
                     VGLFNAVINVVLLVAVNQIVKRMNNGEGI"
     gene            6708..7598
                     /locus_tag="VVR63_001213"
     CDS             6708..7598
                     /locus_tag="VVR63_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU6129234.1"
                     /translation="MKNSIMDTKFDRRILLLNKIIIVFIVLMTLLPLLYIVVASFMDP
                     KVLVSRGISFNPADWTVEGYQRVFSDQSILRGFINSLLYSFGFAALTVLLSVFTAYPL
                     SKKDLVGRRWINYFLIVTMFFGGGLVPTYLLVKELGMLNTPWAIIVPGAVNVWNIILA
                     RAYFQGLPEELVEAAVIDGANDLQIFFKIMLPLAKPIMFVLFLYAFVGQWNSYFDAMI
                     YIKDPNLEPLQLVLRKILIQSQPGQDMIGAQAAMNEMKRLAELIKYATIVISSLPLIV
                     MYPFFQKYFDKGIMAGSLKG"
     gene            7627..9243
                     /locus_tag="VVR63_001214"
     CDS             7627..9243
                     /locus_tag="VVR63_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU6129235.1"
                     /translation="MKFKTFSKSAVLLTASLAVLAACGSKNTASSPDYKLEGVTFPLQ
                     EKKTLKFMTASSPLSPKDPNEKLILQRLEKETGVHIDWTNYQSDFAEKRNLDISSGDL
                     PDAIHNDGASDVDLMNWAKKGVIIPVENLIDKYMPNLKKILDEKPEYKALMTAPDGHI
                     YSFPWIEELGDGKESIHSVNDMAWINKDWLKKLGLEMPKTTDDLIKVLEAFKNGDPNG
                     NGEADEIPFSFISGNGNEDFKFLFAAFGIGDNDDHLVVGNDGKVDFTADNDNYKEGVK
                     FIRQLQEKGLIDKEAFEHDWNSYIAKGHDQKFGVYFTWDKNNVTGSNESYDVLPVLAG
                     PSGQKHVARTNGMGFARDKMVITSVNKNLELTAKWIDAQYAPLQSVQNNWGTYGDDKQ
                     QNIFELDQASNSLKHLPLNGTAPAELRQKTEVGGPLAILDSYYGKVTTMPDDAKWRLD
                     LIKEYYVPYMSNDNNYPRVFMTQEDLDKIAHIEADMNDYIYRKRAEWIVNGNIDTEWD
                     DYKKELEKYGLSDYLAIKQKYYDQYQANKN"
     gene            9253..10572
                     /locus_tag="VVR63_001215"
     CDS             9253..10572
                     /locus_tag="VVR63_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEU6129236.1"
                     /translation="MGDKKYTVEKANRFIAENKHLVNTQYKPEEHFSAEIGWINDPNG
                     FVYFCGEYHLFYQFYPYDSVWGPMHWGHAKSKDLVTWEHLPVALAPDQDYDRNGCFSG
                     SAIVKDDRLWLMYTGHIEEKTGVRQVQNMAFSDDGIHFEKISQNPVVTGTDLPDELIA
                     ADFRDPKLFEKDGRYYSVVAAKHKDNVGCIVLLGSDNLVEWQFESIFLKGGEHQGFMW
                     ECPDYFELDGKDCLIMSPMRYQREGDSYHNINSSLLFTGKVDWGEKRFIPESVQEIDH
                     GQDFYAPQTLLDNQNRRILIAWMQTWGRTLPTHDQEHKWACAMTLPRILRLEDGKLRQ
                     FPVKKGQYQIQIDKDCHYHLGNDIDYLEFGYDSNAQQVYIDRSHLIQKILGEEEQDTS
                     RRYVDIEAKELEVVLDKNSIEIFVNQGEASLTATYYLTVPAELSRID"
     gene            complement(10780..10852)
                     /locus_tag="VVR63_001216"
     tRNA            complement(10780..10852)
                     /locus_tag="VVR63_001216"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10817..10819),aa:Lys,seq:ctt)
     gene            complement(11117..12388)
                     /locus_tag="VVR63_001217"
     CDS             complement(11117..12388)
                     /locus_tag="VVR63_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001113185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HEU6129237.1"
                     /translation="MPDNLALRMRPKTIDQVIGQEHLVGPGKIIRRMVEANRLSSMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKRLQEISEEAKFSGGLVLLLDEIHR
                     LDKTKQDFLLPLLESGLVIMIGATTENPFFSVTPAIRSRVQIFELEPLSNQDVKEALQ
                     IALSNPERGFDFPIELDEDALDFIATSTNGDLRSAFNSLDLAVLSTPENDEGIRHITL
                     DIMENSLQRSYITMDKDGDGHYDVLSALQKSIRGSDVDASLHYAARLIEAGDLPSLAR
                     RLTVIAYEDIGLANPEAQIHTVTALDAAQKIGFPEARILIANVVIDLALSPKSNSAYV
                     AMDKALADLKTSGHLPIPRHLRDGHYSGSKELGNAQDYLYPHNYPGNWVKQDYLPEKI
                     RNHHYFQAEDTGKYERALAQRKEAIDRLRKI"
     gene            12658..12897
                     /locus_tag="VVR63_001218"
     CDS             12658..12897
                     /locus_tag="VVR63_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6129238.1"
                     /translation="MKREVISNGNDGPSQEILIFTKQIRHWILSDQVISGKRKLFFRE
                     DTPKEILDLYENIKSKLDFAYQEVYSNSGLKKYEK"
     gene            13062..13241
                     /locus_tag="VVR63_001219"
     CDS             13062..13241
                     /locus_tag="VVR63_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6129239.1"
                     /translation="MNLIFEEYQFVKIGDKKYRVRSVPMIHSTPPQSVLDRDTFTIDY
                     TDDELLDKEAVFTTH"
     gene            13378..13557
                     /locus_tag="VVR63_001220"
     CDS             13378..13557
                     /locus_tag="VVR63_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HEU6129240.1"
                     /translation="MPMTQKEMVKLLTAHGWIKTRGGKGSHIKMEKQGERPITIPHGE
                     LNKYTERGIRKQAGL"
     gene            13594..14046
                     /locus_tag="VVR63_001221"
     CDS             13594..14046
                     /locus_tag="VVR63_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000961815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HEU6129241.1"
                     /translation="MLVTYPALFYYDDTDGTEATYFVHFPDFEYSATQGEGISEALAM
                     GSEWLGITVADLIESDGELPQPSDINSLSLIDNDPFKDDEDFVSTYDLDKSFISMVSV
                     DVSEYLGSQEPIKKTLTIPKWADKLGREMGLNFSQTLTDAIADKKVQA"
     gene            14337..14807
                     /locus_tag="VVR63_001222"
     CDS             14337..14807
                     /locus_tag="VVR63_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HEU6129242.1"
                     /translation="MATYGFLDILEEELDKNFPFDFEISWDKRNHAVEVSFLLEAQNA
                     AGVEMVDEDGEVSSDDILFEEAVLFYNPAKSTVNAEDYLTVIPYLPKKGFSREFLAYF
                     ALFLKDTAEVGLDTLMDFLEDPEAEEFVMEWNQEVFEEGKVGLEEGEFYPYPRY"
     gene            14826..15914
                     /locus_tag="VVR63_001223"
     CDS             14826..15914
                     /locus_tag="VVR63_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000719715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HEU6129243.1"
                     /translation="MKKIGTYLVYVLAFVFIMLAFACGTIAFAELGYSAVLAFTFGYA
                     FALLSMYLIFILHELGHAFCGYLTGYRLVAFGLGHFILTKKSGRFHLSRTAILKNVGA
                     QYIGLKEDESDQRIILMLSGGLMVHLGLILLAIVFGFLTRSWYFAGTWIFLNLSFFLN
                     NILPVDITDGAKIWELLQHPENTKYAYLVLRHSAQTLLAPQEYDLKDFVQAVPEDARG
                     SFADGVLGMQGEVSILEGKEEVAKQQFQALLERTTTPMMQTVAQLSLLHIALLEGDFE
                     QAEQYASIRQVKSFLSLKLSNLQVIQAWYQFKVKKDVDRTRKALKIARQKMDSSRMLR
                     DEKRYYENLLAELEKEMLEGTEDGTRNF"
     gene            15895..16053
                     /locus_tag="VVR63_001224"
     CDS             15895..16053
                     /locus_tag="VVR63_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="7,8-dihydro-8-oxoguanine-triphosphatase"
                     /protein_id="HEU6129244.1"
                     /translation="MELEISDFPGCKIALFCGDKLLTILRDDKASIPWANMWELPGGG
                     KSVRENLI"
     gene            16163..17197
                     /locus_tag="VVR63_001225"
     CDS             16163..17197
                     /locus_tag="VVR63_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEU6129245.1"
                     /translation="MKKSDVLDLIKYHYEGRETEFRNQSIAIARNFNKHGDTQIAQYI
                     MGLMSQSDRFMPQIENPSEYLTPAKLDIGPLPLPLSIMNDLKGIINAVNHHIGINKFL
                     FVGSPGTGKTESVKQVARLIGKELLVVDFSHLVDSKLGQTVKNLATLFNEINNLPFKQ
                     NYIILFDEIDSIVLDRVNQNDLREMGRVTSAFLKELDRLSPEIVLIATTNLFENLDKA
                     VTRRFDAIIDFDRYTDEDKVEVATIILNELLKQFKNVARDLKLFKKIINSANVIPNPG
                     DLRNSIRTSLAFSDPSDPHDYQKRLLRSLHNGRNLSISKLSKLGFTVREIEILTGISK
                     SSVSRELSED"
     gene            17259..19442
                     /locus_tag="VVR63_001226"
     CDS             17259..19442
                     /locus_tag="VVR63_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family peptidase"
                     /protein_id="HEU6129246.1"
                     /translation="MGPITIPKKTIITLEHLKYLHFSLEETKTYWEKNNIIDGILISI
                     YYNRIVAKSNRINGYFNVGGGNPFPNDTIVGAKFNDEKTKHIVTHYISRDALNKTITV
                     LSKIIEVFEEHFDRAITCEMFSDSSTFASINFSEYGISKSKFQQYLRDSCFIENFGVE
                     HTTVSDIQNSIVTFYDVHTDIFRLLNKLNIDISEANIMNQTTVLLDEKNIELLLSKAP
                     YLVSMIVEDFSKLSVDDFSLDNNDLKINLPSPMNEPVVGVIDTLFDKRVYFNEWVEYH
                     DFVSPDISKDSQDYKHGTAVTSLIVDGANLNPNLDDGCGNFRVRHFGVSLQSGFNSFT
                     IIKQIKEIVSQNADIKVWNLSLGSNDEIRENFISAEGALLDEIQFENDVIFIIAGTNA
                     SVINGKRKRIGAPADSLNSIIVNSVDFNNQSVSYSREGIVLSFFVKPDVSYYGGGNGD
                     FINVCEPLGLGRVAGTSFAAPFIARKMAYLIHIMGLSREEAKALLIDAAIPWNDKKTF
                     TDLSLIGNGIVPIKMDDILSTPDDEIKFIVSDISRAYDTYNYDFPVPISSESYPYVAK
                     ATMCYFPNCSRKQGVDYTNTEMQLTFGRLKSDGIKSINKDNQHAEDTPGYVRENAARN
                     IFRKWDNVKHIGESFTSRKRAKAILNPSNPQWGMSIKTIERLKSGDGQGVRFGVVVTL
                     KELNGVNRIEDFIQQAELRGWLVNRLQVEAQVDLFNSLNEEIEFE"
     gene            19493..20509
                     /locus_tag="VVR63_001227"
     CDS             19493..20509
                     /locus_tag="VVR63_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001028052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HEU6129247.1"
                     /translation="MNITYIVGNGLDLQYGLKTRYRDFYEFQNKVYISRTENEEKYSN
                     FIYESLFSDKVNDYENWSDFELSIGKLTKDNDLISSSIEIKEKFIDDFSEVVDDLREY
                     LRIQQEKNLEKGNAIDFISTLDDMRTSLPVINQPAIDKKYNENPHQDDIVNIVTLNYT
                     HVIDKLYNGSAKSFRNQLRANLYNFYIEPPIHAHGTVDVCTVLGVSDEIQISNSLEEQ
                     KESLIKSLVLKNYRENMDVKNSDIIKNSDIIILYGVSLGETDRYIWSQIAERSISGSV
                     PVIIYHYVPHFDPGNPIRAKRLYRNVEDKFIQNSGIDLELEKKLRDNLIVVIGKTIFD
                     LIER"
     gene            20524..21474
                     /locus_tag="VVR63_001228"
     CDS             20524..21474
                     /locus_tag="VVR63_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000451122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HEU6129248.1"
                     /translation="METWQELKVTVKREGEELVSNLLIELGAQGVAIEDSLDYVGNVD
                     RFGEIFPEVEQQEEIVVTAYYPDTVDVTVVEADLQARLAELTDFMDLGELKIGTTALA
                     EEDWADNWKKYYEPARITHDLTIVPSWTDYEATAGEKIIKLDPGMAFGTGTHPTTKMS
                     LFALEQVLRGGETVLDVGTGSGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNPG
                     MENIHVAAGDLLKGVEIEADVIVANILADILIHLIDDAYRLVKDEGYLIMSGIIKDKW
                     DMVRESAESAGFFLETHMIQGEWNACVFKKTKDISGVIGG"
     gene            21476..22219
                     /locus_tag="VVR63_001229"
     CDS             21476..22219
                     /locus_tag="VVR63_001229"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001188214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HEU6129249.1"
                     /translation="MQQYFVKGSAISPVTIEDKEISKHMFQVMRLKEEDEVTLVFDDG
                     IKRLARVLDMENRQFELVQELNDNVELPVQVTIASGFPKGDKLEFIAQKVTELGASQI
                     WAFPADWSVAKWDGKKLGKKVEKLEKIALGAAEQSKRNIVPSIKLFEKKADFLAQLDQ
                     FDSIIVAYEESAKEGEAAALLQAVTGLETGAKLLFIFGPEGGLSPAEIESFEAKGAVL
                     AGLGPRILRAETAPLYALSALSVLVELEK"
     gene            22230..24026
                     /gene="pepF"
                     /locus_tag="VVR63_001230"
     CDS             22230..24026
                     /gene="pepF"
                     /locus_tag="VVR63_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEU6129250.1"
                     /translation="MEQKHRSEFPEKELWDLTALYQDREDFLRAIEKAREDINQFSRD
                     YKGNLHTFEDFEKAFAELEQIYIQMSHIGNYAFMPQTTDYSNDEFANIAQAGMEFETD
                     ASVALTFFDDALVVADEEVLDRLGELPHLTAAIRQAKIKKAHYLGADVEKALTNLGEV
                     FYSPQDIYTKMRAGDFEMADFEAHGKTYKNSFVTYENFYQNHEDAEVREKSFRSFSEG
                     LRKHQNTAAAAYLAQVKSEKLLADMKGYDSVFDYLLAEQEVDRVMFDRQIDLIMKDFA
                     PVAQRYLKHVAKVNGLEKMTFADWKLDLDSALNPEVTIDDAYDLVMKSVEPLGQEYCQ
                     EVARYQEERWVDFAANSGKDSGGYAADPYRVHPYVLMSWTGRLSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNAHMSTYYVEAPSTFNELLLSDYLENQSNDPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGETFGASKLNSIMKEVLTDFWGDAIEIDDDAALTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLHLKNSETGAEDWLNLLKSGGSKTPLESAMIIG
                     ADISTDKPLRDTIQFLSDTVDQIIAYSAELGE"
     gene            24273..25064
                     /locus_tag="VVR63_001231"
     CDS             24273..25064
                     /locus_tag="VVR63_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2785 domain-containing protein"
                     /protein_id="HEU6129251.1"
                     /translation="MYQDLLRKIAEEKPNYNQEEIQWLLDHLGDPSPEIRDDLVFTSF
                     ARGIQEELFTQEQFHFIAEGVSSDGGLDKEIDKIGLPTLERSFRALIYATLLSDDANQ
                     QSIFYQRLKAEIRNVLLNQGLHYLSKEKDTTGFSSQYGWVHSFAHGADLLKEVVCHPD
                     FPKNRVHEVFDILGQLFKRMSIRFTDDEDWRLARVIYEPILQGKLEQEQVASWIKTVD
                     FPIEEREDFSKFSNFRSCLVEVYVQLDQRNSLQDELKEAIQSFQY"
     gene            25175..25843
                     /locus_tag="VVR63_001232"
     CDS             25175..25843
                     /locus_tag="VVR63_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin"
                     /protein_id="HEU6129252.1"
                     /translation="MKKFVAELIGTFMLVFVGTGAVVFGNGFDGLGHLGIAFAFGLAI
                     VVAAYSIGTVSGAHLNPAVSIAMFVNKRLSSSELVNYILGQVVGAFIASGAVFFLLAN
                     SGMSTASLGENALANGVTVFGGFLFEVIATFLFVLVIMTVTSESKGNGPIAGLVIGLS
                     LMAMILVGLKITGLSVNPARSLAPAVLVGGAALQQVWIFILAPIAGGVLAALVAKNFL
                     GTEE"
BASE COUNT         8223 a         4318 c         5329 g         8084 t
ORIGIN      
        1 tattatttca ttttactata cattatgaaa aaggggagat agaaagcaaa cagccttgaa
       61 atcaatgttg actgcgatta tgaacctgaa tcagcccctc aaaagggact gtatatgaat
      121 gaacgttacc agtgtttaaa aactaaagaa tatcaggcac ttttatcttc caagggtaga
      181 caaattttcg ctaaacgtaa gattgatatg aaatctgtct ttgggcagat aaaggtttgt
      241 ttgggttata agagatgtca tctgagaggt aagcgtcaag tgagaattga catgggattc
      301 atactcatgg ccaacaacct gctgaaatat aataagagaa agaggcaaaa ttaaaaagct
      361 agagttccgc aattgggaat ctctagcttt ttgttttctg agaatcatct tgactcagac
      421 tcttttgact aatgttacca aaaaagataa agtaactttt aaccttattt atcgtcgcca
      481 ctcaacatgt ttttaacacc ttctacagca ccttctacag cgtctttagc gtcttcggca
      541 acttctttta ctttagaaac aactttttca gctgctcctt ctttttccat tttttcatca
      601 ccgatggctt tcccaacacc ttctttaata gaacctttag cttgatttaa tttttcttct
      661 actgacatga taatttctcc tgttatattt attttatctt agtttacacg agtgttttcg
      721 tgagatacta caccatttgc tgcaccttta acagcttcta caccttcgct aactttttct
      781 tgaacagttg agaaaccaga tccaagacca gatttagctt tttcgaattg ttctgaagtg
      841 aattctcctg ttgattcagc aacgtcagat acgcgatctt gaaggcttac tgagtctgct
      901 tcatgctgtt ctttagtttt gatgtcgaca acgtttacgt tgatttcaac aatttccaag
      961 tcagtcattt tagcaacttc tgaagatacg atttctctga tttctgaata taaagctgga
     1021 acattttttt ggtactcaac aataacgttt aagtcaactg caacttgtgt tttaccaact
     1081 tctacgttaa caccacttgt tacgtcatcg ctgttaacga ttttttcttt aagatttgag
     1141 aagaaaccac catcgattcc caaaagacct gaaacgtttt ctagtgaaag accaatgatt
     1201 ttttggataa ctttatcttc gtaagtaagt tcccctttga tttcgtgagc tacaacagta
     1261 gcatctttct tttctacgtt agtgtttgtg tttttttcgt ttgacatatg aaactccttt
     1321 aattaaatta gtaattttta tttttttatt tatctatata gtttttttcg atatataatc
     1381 cagctgcaac tcccagtgct cctaaaatca atacaaatat tgttttgaag aagccaaagg
     1441 agacaatcaa acaagccaga aatacgccta tgagaccagc gataattgga tatcgatatt
     1501 gtttaagcca ttccattttt tacttcctta cttcacacga ctaacagtct ttttgttttg
     1561 aggttttggt tggtaatttt ttactgcaac ttcaagtttt acttgacgct caataccaaa
     1621 aaactgcttc aatccattag ttatttcatt ttgaattatt tggcatctgt cagcgatgtt
     1681 gtctgaagga agaattttac cttctacatg aacgaaacat ttattttttc gtaaatttac
     1741 atgaacagtt gggttcttga tcaatctatg atcactcacc aaacttctaa caaaaccttc
     1801 gattgccgaa ttctttaatt ttaatgtatc gtttttagtt tcaagttgga tttccaagta
     1861 acgtttagga taaaacatca caactaaaat ggataataaa actaaagttg atagaaccac
     1921 tgtcccccaa aagacatatc tagcaagata gaattcaact acggagttct gtctccagct
     1981 aagtagatga atacctagat cactaacttg atgataatct atcaaaacag gaaggaaaat
     2041 tgtcaagatt aaaatacaga aaataatgaa acatattttc tttgcttttg acatatacaa
     2101 tcctttcgat ttaacattta aactattttt cccgtcattg atttaaaaat agtttgctaa
     2161 ctttactggc gaaaagttta ctttctacct gtaaagaatg acactacagt aatcacaatc
     2221 gctgcaccta caatagatgg gagcaaagcc attccagcga ttgatggacc ccaactacct
     2281 aaaagagatt gtcctgcata tgccccgact aaaccagcga atacatttgc gatgattccc
     2341 atagaactac ttttttagtg attttacctg ccaagagacc aataagacct ccagcaataa
     2401 ttgatcacaa cactgcctac cctccttttt tattttaata tcaaaaaatc aatttctttg
     2461 attaatacta ttatataact ttaatataga aaagtcaatt atttcgattg ttattattat
     2521 ataattttaa aaaatcaaat tctttaattg ttgctattat ataattttta aaattaaaaa
     2581 tataatcttt agacttgaat ttgattctgt attcacgccc tcaatagacg gtaaaataag
     2641 aaaattgttt atatattgtc tccgtagtgt tattatacga aataaaagat tttaggaaaa
     2701 gtcgttatat catgctatac ctattctttg tggtataatt gcaagaggtt taatccgata
     2761 atttataaag agagaaagat attcatgaga gatttattat ctaaaaaaag tcataggcaa
     2821 ttagaattat tagaattatt atttgaacat aaacgttggt ttcatcgttc tgaactagca
     2881 gagttattaa attgtacaga acgtgcagtc aaagatgatc tatcccatgt taaatctgct
     2941 tttcctgact tgatttttca ttcttctact aatggtatac gcattattaa taccgatgat
     3001 agtgatattg aaatggttta ccatcatttc tttaaacatt caactcattt ttcgatttta
     3061 gaattcatct tctttaatga aggttgtcaa gctgagagta tttgtaaaga attttatatc
     3121 agttcatctt cgctctatcg tattattagc caaatcaata aagtgattaa aaggcaattt
     3181 caatttgaag tcagtctgac ccctgttcaa atcattggaa atgagagaga cattcgttac
     3241 ttttttgcac aatatttttc agaaaaatat tatttcctag aatggccatt tgaaaatttt
     3301 tcatcagagc cactatctca attgttagaa ttggtttata aggaaacaag ctttccaatg
     3361 aatttgtcaa cgcatagaat gctaaagttg ctcctagtta cgaacctata tagaataaag
     3421 tttggtcatt ttatggaagt agataaagat tcttttaacg accaaagttt ggatttttta
     3481 atgcaggcag aaggaataga aggtgttgct cagagttttg aatcagaata caatatctct
     3541 ttagatgaag aagttgtttg ccaattattt gtgtcttact ttcaaaaaat gtttttcata
     3601 gatgaaagtc tctttatgaa atgcgtaaaa aaggatagtt atgttgaaaa atcttaccat
     3661 ctattgagtg attttattga tcagatttca gtcaagtatc agattgaaat ggagaataag
     3721 gataatctga tttggcatct gcataatacc gcacatctgt atcgtcaaga gttgtttact
     3781 gagtttattt tatttgatca aaaagggaat acaatcagga actttcaaaa tatttttcca
     3841 aaatttgttt cagatataaa aaaagagctt tctcactatt tagagactct tgaggtttgt
     3901 tctagttcaa tgatggtaaa tcatctatct tataccttca tcactcatac caaacatttg
     3961 gtgattaatt tgctacaaaa tcagcctaaa ctaaaggttt tagttatgag taattttgat
     4021 cagtatcatg caaaattcgt tgcagagaca ctttcttatt actgtagcaa taattttgaa
     4081 ctggaagttt ggactgaatt agaattatca aaggaatctt tagaagattc accttatgat
     4141 atcattattt ctaattttat tattcctcct attgaaaata agagactcat ctattcaaat
     4201 aatataaaca cggtctcact catatacttg ttaaatgcca tgatgtttat tcgattagat
     4261 gagtaaccaa aaataacaaa aaaacgctat ttcgcgtttg aactgtacct caaaagttag
     4321 acagaaaaaa tctaattttt ggggtgtttt tgttaagaaa agaccttcaa tcatttaagc
     4381 aaaatgtaca tctagattta tagccctcta aaactcttgc tttttttgta gaagatacga
     4441 aaaaagccat aaaaccaagg cttttcctgt tttatgtaga tgtttacaca tgaaaattga
     4501 agtattttca aaagctaatt ggagtgattt tattcatgat gggataaatg atctggccaa
     4561 aaatgattga gaaatagttg cttaaaaagc atttgcatga tactatatat tgaaaggagg
     4621 tgataatatg gtagaacaaa gaaaatcaat taccatgaaa gatgttgctt tagaagcagg
     4681 agttagtgtt ggaactgttt cacgtgtaat taataaagaa aaaggcatta aagaagtaac
     4741 tttgaaaaaa gtggaacaag cgattaaaac tttgaattac attccagatt actatgctag
     4801 aggaatgaaa aaaaatcgaa cagaaacgat tgcaatcatt gtaccaagta tctggcatcc
     4861 cttcttttca gaatttgcta tgcatgtgga aaatgaagtc tataagagaa ataacaaatt
     4921 actcttatgt tctataaatg gtacaaatag agagcaagac tatctggaga tgttgcgtca
     4981 taataaagtt gatggagtgg ttgccattac ctatagtcca attgaacatt acttgacgtc
     5041 aggaattccc tttgttagta ttgaccgcac atactcagat attgccattc cttgtgtttc
     5101 atcagataat gatgcaggtg gaagagaagc agctaaacaa ttaattagta aaggatgtca
     5161 gcatttagcc tttgtgggcg gacataatac aaccattaat gaaaccaaac gtcgtagaat
     5221 ttcatttgaa aagtatgtcc aagagcataa aatacctctt agtatttttg atttggatga
     5281 gacagttact gactattatg gaaagctaga gagtttcttg gaagaaaatt cttctataga
     5341 tggaattttt acaatcaacg attttacagc tttggatgtg attgaaatac tagaaaaaaa
     5401 tggcaaacgt attcctcatg atgtccaaat tattggatac gatggaatta aaatggctgg
     5461 agatagagat tatctacttt caactattga acaaccattg gaagaaatgg caaaagaagc
     5521 ggttcgtatt ttgtttgata taattgatgg aaagactgtt aatttgcaga caatcctacc
     5581 agtaaaattt gttgaaggaa aaacaacaaa aaatgaaaat aagtcttgac agaaagcgct
     5641 atcaatgata gaatgaattc agataaaaag atttattttt aaaacaaaaa tgaaacgttt
     5701 caaaaaaaga aataaaaaga cagcgccaag cgctatcttt tatagaaaaa atgaaacgtt
     5761 tcaaaaaaag gaggttgcta tgaatagcaa agcgaagcaa gtttctcttt gggaaagaat
     5821 caagaaacaa aaactcttgt tattgatgac tgtccccggt ttagttttaa cctttatctt
     5881 taaatacatc cctatgtatg gggttttaat cgcatttaaa gattacaatc ctttaaaagg
     5941 aattttaggg agtgattgga ttggtttttc tgagtttaca aaattcatat cctctcccaa
     6001 ctttggtatc ttgttagcca acacattaaa attaagtatc tatggtttat tgcttggctt
     6061 tttaccacca atcattcttg cgattatgct caatcaactc ttgagtgaaa aagtcaaaaa
     6121 acgaattcag ctcattttat acgcaccaaa ctttatctca gtcgttgtta ttgtcggtat
     6181 gattttcctc ttcttttcag tgggaggacc aatcaacaat tttctttcta tgtttggaat
     6241 gaaggctgac ttcttgacaa atccagactt ctttagaccc ttatacatct ttagtggtat
     6301 ctggcaagga atgggctggg cttcaacgct ctacacggca acattggtaa atgtagatcc
     6361 agccttagta gaagcagctc gactggatgg agccaatatc ttccaacgaa tctggcacat
     6421 tgatattcca gctcttaagc ctattatggt tatccaattt gttttagctg caggtggaat
     6481 tatgaatgtc ggatatgaaa aagcattctt gatgcagaca tcgttaaatt tgccaacttc
     6541 tgaaattatc tcgacatatg tctataaagt tggtcttgta tcaggagact attcttactc
     6601 aacagcggtt ggtttgttta atgcagtgat taacgtagta ttgcttgttg cagttaacca
     6661 aatcgttaaa cgcatgaata atggtgaagg aatttaagga ggaaagtatg aaaaattcga
     6721 ttatggatac aaaatttgat agacgtatct tactcttaaa taaaatcatt attgtcttta
     6781 tcgttttgat gactttgctt cctttacttt atatcgtcgt agcatccttt atggatccta
     6841 aggttctggt tagtagaggg attagcttta atccagccga ttggactgta gaaggttacc
     6901 agcgtgtatt cagtgaccaa tctattctaa gaggttttat caattctcta ctatactctt
     6961 ttggatttgc agctttaaca gtattgctat ctgtgtttac agcttatcct ctttctaaga
     7021 aagacttggt tggacgtcgt tggattaact acttcttgat tgtgactatg ttctttggtg
     7081 gtggtttagt cccaacttac ttgctcgtaa aagaattggg aatgctcaat actccatggg
     7141 ctatcattgt tccaggtgct gtcaatgttt ggaatattat tcttgctagg gcctatttcc
     7201 aaggattgcc tgaagaatta gttgaagctg ctgtcattga tggagcgaat gacttgcaga
     7261 ttttctttaa aatcatgctt cctcttgcaa aaccaattat gtttgttctc ttcctctatg
     7321 cttttgtagg acagtggaac tcatactttg atgcaatgat ttatatcaag gatccaaact
     7381 tggaaccatt gcaacttgta cttcgtaaaa ttctcattca gagccaacca ggtcaagaca
     7441 tgattggagc acaagcggct atgaatgaaa tgaaacgttt agctgaattg attaaatacg
     7501 caactattgt catttccagc ttgccattga ttgttatgta tccattcttc caaaaatact
     7561 ttgataaagg aattatggct ggttcactta aaggataaaa aaagaaaaaa taaaaggagt
     7621 tttctcatga aattcaaaac attctcaaaa tcagcagttt tgttgacagc tagtttagca
     7681 gtacttgcag cctgtggctc aaaaaataca gcttcaagtc cagattataa gttggaaggt
     7741 gtaacattcc cgcttcaaga aaagaaaaca ttgaagttta tgacagccag ttcaccgtta
     7801 tctcctaaag acccaaatga aaagttaatt ttgcaacgtt tggagaagga aactggcgtt
     7861 catattgact ggaccaacta ccaatccgac tttgcagaaa aacgtaactt ggatatttct
     7921 agtggtgatt taccagatgc tatccacaac gacggagctt cagatgtgga cttgatgaac
     7981 tgggctaaaa aaggtgttat tattccagtt gaaaatttga ttgataaata catgccaaat
     8041 cttaagaaaa ttttggatga gaaaccagag tacaaggcct tgatgacagc acctgatggg
     8101 cacatttact cattcccatg gattgaagag cttggagatg gtaaagagtc tattcacagc
     8161 gtcaacgata tggcttggat taacaaagat tggcttaaga aacttggtct tgaaatgcca
     8221 aaaactactg atgatttgat taaagtccta gaagctttca aaaacgggga tccaaatgga
     8281 aatggagagg ctgatgaaat tccattttca tttattagtg gtaacggaaa cgaagatttt
     8341 aaattcctat ttgctgcatt tggtataggg gataacgatg atcatttagt agtaggaaat
     8401 gatggcaaag ttgatttcac agcagataac gataactata aagaaggtgt caaatttatc
     8461 cgtcaattgc aagaaaaagg cttgattgat aaagaagctt tcgaacatga ttggaatagt
     8521 tacattgcta aaggtcatga tcagaaattt ggtgtttact ttacatggga taagaataat
     8581 gttactggaa gtaacgaaag ttatgatgtt ttaccagtac ttgctggacc aagtggtcaa
     8641 aaacacgtag ctcgtacaaa cggtatggga tttgcacgtg acaagatggt tattaccagt
     8701 gtaaacaaaa acctagaatt gacagctaaa tggattgatg cacaatacgc tccactccaa
     8761 tctgtgcaaa ataactgggg aacttacgga gatgacaaac aacaaaacat ttttgaattg
     8821 gatcaagcgt caaatagtct aaaacactta ccactaaacg gaactgcacc agcagaactt
     8881 cgtcaaaaga ctgaagtagg aggaccacta gctattctag attcatacta tggtaaagta
     8941 acaaccatgc ctgatgatgc caaatggcgt ttggatctta tcaaagaata ttatgttcct
     9001 tacatgagca atgacaataa ctatccaaga gtctttatga cacaggaaga tttggacaag
     9061 attgcccata tcgaagcaga tatgaatgac tatatctacc gtaaacgtgc tgaatggatt
     9121 gtaaatggca atattgatac tgagtgggat gattacaaga aagaacttga aaaatacgga
     9181 ctttctgatt acctcgctat taaacaaaaa tactacgatc aataccaagc aaacaaaaac
     9241 tagaggttga ttatgggaga taagaaatac acagtagaaa aagccaatcg ttttatagca
     9301 gaaaataaac atctcgttaa tactcaatat aagcctgaag aacatttttc agctgagatt
     9361 ggttggatca atgatccaaa tggatttgtt tatttttgtg gagaatacca tctcttttat
     9421 caattctatc catatgatag tgtttgggga cctatgcact ggggacatgc taaaagtaag
     9481 gacttggtga cttgggagca cttgccagtg gcacttgctc ctgatcaaga ttatgaccga
     9541 aatggttgtt tctcaggctc tgccattgtc aaggatgatc gcctctggct catgtacact
     9601 gggcatatcg aagaaaaaac cggtgtccgc caagtgcaaa atatggcatt ttcagatgac
     9661 gggattcact ttgaaaagat ttcccaaaat ccagttgtaa ctggaacaga cttgccagat
     9721 gagttgattg ctgctgattt ccgtgatcca aaactctttg aaaaagatgg acgctattac
     9781 tctgtagtag ctgccaaaca caaggataat gtgggctgta tcgttctact agggtccgat
     9841 aacctagtag aatggcagtt cgaatccatc tttttaaaag ggggagaaca ccaaggcttt
     9901 atgtgggaat gcccagatta cttcgagtta gatgggaaag attgccttat tatgtcaccc
     9961 atgcgttatc agcgtgaggg agactcatat cataacatca actcatcgct tttgttcacg
    10021 ggtaaggtag attggggaga aaaacgtttt atcccagaat cagttcaaga aattgatcat
    10081 ggccaagact tctatgcgcc tcaaacattg ttggacaatc aaaatcgtcg tatcctgatt
    10141 gcttggatgc agacatgggg gcgtaccctt ccaacccatg accaagaaca caaatgggca
    10201 tgtgccatga ctttacctag aattctaaga ttggaagatg gcaaactaag acaattccct
    10261 gttaaaaaag gccaatatca aatccaaata gataaagatt gtcattacca cttaggaaat
    10321 gatatagatt atcttgaatt tggttatgac agtaatgcgc agcaagttta cattgatcgt
    10381 agccatctta ttcaaaaaat tctaggtgaa gaagaacagg acactagtcg acggtatgta
    10441 gatattgaag ctaaagaatt ggaagttgtt ctagataaaa attccatcga gatttttgtc
    10501 aatcaaggtg aagcaagctt gactgcaact tattacttaa cggtgccagc tgagctatca
    10561 cgaattgatt aaaaattaag ttatttctcc taaagaaaaa gttctctttc taaaatagtg
    10621 gaaagaggac tttttgtgtt ttgggtatat aagcttagtt tatggtattt gtaaaattgg
    10681 tgttggatta tgatttaagc tagttttcta aagaatttga aaaaaatttt atttaagcaa
    10741 aaaaaccttg gttccaaggc ttttcctgtt gtatttagat gccccctaca ggaatcgaac
    10801 ctgtgaccca cggattaaga gtccgctgct ctgccagctg agctaaggag gcaaagaaaa
    10861 aagctgtatt ggtgccgaaa cttcacggtt tgtattgaac ccgcgcaatt aagcaggtgg
    10921 gcaactcgct ctaactgaag ctgtttccgt gtgagacggc ctacatgctg ttagaagact
    10981 tttgtttccc taataataca aaaaatagtc ggtcaacact taagtgtgaa gtcgtacacc
    11041 acagcgtttc tatacttata tgataccact ttttcaaaaa aaatcaagag gaaagtgcaa
    11101 ttttttgaaa aggatttcag atttttcgca aacggtcgat agcttccttt ctttgagcca
    11161 aagcccgttc atatttacca gtatcttctg cttggaaata gtgatgatta cgaatttttt
    11221 ctggcagata gtcttgcttg acccaatttc caggatagtt gtgtggatag agatagtctt
    11281 gggcattccc cagttccttg cttccactgt agtgcccatc acgtaggtgt cgcggaatag
    11341 gcaagtgccc tgatgttttg aggtcagcaa gtgccttatc catagctaca taggctgagt
    11401 tggattttgg agaaagtgcc aaatcaatca cgacattggc aatgagaatg cgggcttctg
    11461 ggaacccaat cttctgggca gcatccagag cagtcacggt atgaatctgg gcctcaggat
    11521 tggctaagcc gatatcttca taggcgataa cagtcaagcg acgagcgaga ctaggcagat
    11581 ccccagcctc aatcaagcgg gcagcatagt ggagactggc atccacatct gagccacgga
    11641 tagacttttg cagggcagat agaacatcat agtgaccgtc tccatccttg tccatagtga
    11701 tgtagcttct ctgaagacta ttttccatga tgtctaaggt gatgtggcga atgccctcgt
    11761 cattctcagg ggtagagaga acagccaagt ccagtgagtt aaaggcagag cgaaggtctc
    11821 cgtttgtaga ggttgcgatg aaatccagcg catcctcatc tagttctatt ggaaaatcaa
    11881 aaccacgttc agggttactt agagctatct gcagggcctc tttgacgtct tggttagaca
    11941 gaggttccaa ctcgaaaatt tgaactcggc tacgaatggc aggagtgaca gagaagaaag
    12001 gattttcagt cgttgctcca atcatgatga ccagtccact ttccaagaga ggcaagagga
    12061 agtcttgctt ggtcttatct agtcgatgaa tttcgtctag caataggacg agaccaccag
    12121 aaaatttagc ttcttccgag atttcttgca gtcgcttttt actatcaact gtcgcattga
    12181 aagttcgaaa ggcatacttg gtcgttccag cgatggcaga ggcaatactg gttttgccga
    12241 ttcccggagg gccgtataga atcatggagg acaggcggtt ggcttccacc atgcggcgga
    12301 tgatttttcc aggtccgacc agatgctcct gaccgatgac ctggtcgatg gttttagggc
    12361 gcatgcgaag cgcgagattg tctggcatag cagtcctttc taacgtggat ttgagtagaa
    12421 tgactcatct actatatctt actatgtcca ttctagccta ttagttgtga tatttcaatg
    12481 gttttgtaat aatcagggag tgagatagaa tcttttttac tatttaattt aatgaggaga
    12541 ggtatcagca tgagagattt gattttcctt aaagctcaaa ataggatagt tgagcctaaa
    12601 gaagtggaag tgctgacttg agaaataata ttgctgaatg tcattgtatg aactataatg
    12661 aaaagagagg tgataagcaa tggaaatgat ggaccaagtc aggaaatttt gatttttaca
    12721 aaacaaattc gtcattggat tcttagtgat caagttattt cagggaaaag aaaacttttc
    12781 ttccgggaag atactccaaa agagatttta gatttgtacg aaaacattaa atctaaactt
    12841 gattttgctt accaagaagt ttattctaat agtgggttga aaaaatatga aaaatagaat
    12901 aattgatgtt tttgaagtag taaatcgcat ccttgtaata actgttgaaa atcctgattt
    12961 cgaagacttg agagttaatc atactcaatg aaaatcaaag agcaaactag gaaactagcc
    13021 gcaggctgta cttgagtacg gtaaggcgac gttgacgtgg tttgaatttg attttcgaag
    13081 agtatcagtt tgtaaaaatt ggagataaaa aatatagagt acgcagtgtt cctatgattc
    13141 attcaactcc gcctcaatct gtcttagatc gagatacttt tacaattgac tatacagatg
    13201 atgaattgct cgataaagaa gcagttttta ctactcatta gaaaaatagg tatgaataaa
    13261 ttggcttccc ttagaaccac atctaggggc ttttatgtat aatagaataa taagtatcac
    13321 tcctttacaa tacgtgtaac acgtgttata atggtgttgt caggaggtaa aagcgctatg
    13381 cctatgacac aaaaagagat ggttaaactc cttacggccc atggttggat aaagactaga
    13441 ggcggtaaag gttcccatat taaaatggag aagcaagggg aaagacctat cacaatccct
    13501 catggtgagc tgaataagta cactgaaaga gggataagaa agcaagctgg gttgtaaaat
    13561 tcagcccctg ctttttgata tggaggtagt gaaatgttag ttacgtatcc agctttattt
    13621 tattatgacg acacagacgg aacagaagcg acttattttg tccatttccc agattttgaa
    13681 tactcagcta cacaaggaga ggggatttct gaggctttgg ctatggggtc ggagtggcta
    13741 gggataactg ttgcagattt gatagagagt gatggagagt tacctcagcc atcagatatc
    13801 aatagcttgt ctttaattga taatgatcct tttaaagatg atgaagattt cgtgtcaacc
    13861 tatgaccttg ataaatcttt tatttctatg gtatctgttg atgtatcaga atacctagga
    13921 agtcaggaac ccattaaaaa gactttgacc ataccaaaat gggcagataa gttgggacga
    13981 gaaatgggac ttaacttttc tcagactttg acagacgcta ttgcagataa gaaagttcaa
    14041 gcctaagatt aagcgtggta tcgtggtaat agtcaataaa aaagcacgtc cacttgtgct
    14101 agttactcgc ctattgattt tatagattta ttagcccttt cgcgggcttt ttatattgat
    14161 ttttatgaga aatgaagaaa tcagactttt aagaaaatca ctgataccaa gggtttaaat
    14221 gaggtaatat ggtataatta ggacataaaa taattttgtg gtaagatggt agtatctatt
    14281 ttagcatatt tccgagcaat cggggcgatt aaagagtcgc atagaaagag ggcaaaatgg
    14341 caacatacgg atttttagat attttagagg aagagttgga caagaacttt ccctttgact
    14401 ttgagattag ttgggacaag cgtaaccacg cggtagaagt gagttttcta ttggaagcgc
    14461 aaaatgctgc aggtgtggag atggtggatg aagacggaga ggtttcatca gatgacattc
    14521 tttttgagga agcggtcctt ttctacaatc ctgccaagtc aaccgtcaat gcagaagact
    14581 atttaacggt tatcccttat ctacctaaaa aaggattttc tcgcgagttt ttagcttatt
    14641 ttgccctttt cctcaaagat actgctgagg ttgggctaga taccctcatg gactttttgg
    14701 aagatccaga agcagaggaa tttgtcatgg aatggaacca agaagtcttt gaagaaggaa
    14761 aagttggttt ggaagaggga gaattttatc cttatccaag atactaggag ttggttggag
    14821 gtgttatgaa gaaaattggg acttatttgg tttatgtgct agcttttgtc tttattatgc
    14881 tagcttttgc ttgtggaaca atcgcatttg cagagttggg gtattccgca gttttagcct
    14941 ttacttttgg ttatgccttc gctcttctaa gcatgtattt aatctttatt cttcatgagc
    15001 tgggtcatgc tttttgtggc tacttgacag gctatcggct ggtggctttt ggattaggac
    15061 attttatttt gaccaaaaag tcaggcaggt ttcatcttag tagaacagcc attctgaaaa
    15121 atgttggtgc tcaatacatt ggtttaaaag aggatgaaag cgatcaaaga atcatcctga
    15181 tgctttcagg aggcttgatg gttcatctcg gcttgatatt attggcgata gtgtttggat
    15241 ttttgacaag aagctggtat tttgcaggga cttggatttt tcttaattta tctttcttcc
    15301 taaataacat tttgccagtc gacatcaccg atggagcaaa aatttgggaa ttactacaac
    15361 accctgaaaa taccaaatac gcctacctgg tattgagaca ttctgctcaa actttgctgg
    15421 ctcctcaaga atatgatttg aaagactttg ttcaagcagt tcctgaggat gcacgaggga
    15481 gttttgcgga tggtgtatta ggtatgcaag gtgaagtttc cattttggaa gggaaggaag
    15541 aagtagctaa acagcagttt caagcattac ttgagaggac aactactccg atgatgcaga
    15601 cagttgccca actatccctg cttcatatcg ccttgttgga aggagatttt gagcaagcgg
    15661 agcaatatgc tagtattcga caggtcaaat cgtttctgtc tctcaaactg tccaatcttc
    15721 aagtgataca agcttggtat caatttaagg taaagaaaga tgtagatcga actcgtaagg
    15781 ctctcaagat tgctagacag aaaatggata gtagtcgaat gttgagggac gagaaacgct
    15841 attatgaaaa cttgttagca gagctggaaa aggaaatgtt agaaggaact gaagatggaa
    15901 ctagaaattt ctgatttccc aggctgtaag attgctttgt tttgtgggga taagctcttg
    15961 actatcttac gtgatgataa ggcaagtatt ccctgggcca atatgtggga actgccaggt
    16021 ggtggaaaga gtgtcaggga aaatctgata tagttttgta ttaaaagaat atcctttcaa
    16081 ggttattctt ttttaatttt gtcccaaaat aattgacttt gtcccgaaaa tatagtatta
    16141 tttgtataag gaggaatgaa tcatgaaaaa atcagatgtt cttgatttaa taaagtatca
    16201 ttatgagggc agagagacag aatttagaaa tcaatccata gcaattgctc ggaacttcaa
    16261 taaacatggt gatacacaaa tagcacaata tattatgggg ttaatgtctc aaagtgatag
    16321 attcatgcca caaatagaaa atcctagtga gtatttgact cctgctaaac tagatattgg
    16381 tcctctccca ttgcctcttt caattatgaa tgatttaaaa ggaataataa acgctgtcaa
    16441 tcatcatatt ggaataaata aatttttatt tgtgggatct ccaggtactg gaaaaactga
    16501 aagtgtaaag caggtggcta gacttattgg caaggaatta cttgtagtag atttcagtca
    16561 cttagtagat agtaagctag ggcaaacagt caaaaactta gcaactcttt ttaatgaaat
    16621 caataatctt cctttcaagc aaaattatat catcctattt gatgaaattg attccatagt
    16681 gttggatagg gttaatcaga atgatttaag agaaatggga cgagtgactt ctgccttttt
    16741 aaaggagttg gataggctgt caccagaaat tgtattaatt gcaacaacaa atctttttga
    16801 aaatcttgat aaagcagtta cgagaagatt cgatgccata attgactttg accgttatac
    16861 tgatgaagat aaagtagaag tagctactat tattttaaat gagttattaa agcaatttaa
    16921 gaatgtagct agagatttaa aattatttaa aaaaattatc aatagtgcca atgtaatacc
    16981 gaatcctggt gatttgagaa actcaataag aacgtcattg gcatttagtg acccatcaga
    17041 tccgcatgat taccaaaaac gcctgctaag aagtttgcat aatggtagaa atttatctat
    17101 ttctaaatta tcgaagctag gttttactgt tagagaaatt gagattttga caggtatttc
    17161 taagagtagt gtatcacgag agttaagcga ggattaaaat gaatacatta ttgacattac
    17221 gaggtaaaag ttttacacaa aaatcaagaa ataatggtat gggaccaata actataccca
    17281 aaaaaacaat aattacattg gaacatttga agtatcttca tttttcatta gaagagacga
    17341 aaacatattg ggagaaaaat aacattatcg atggtatttt gatcagtatt tactataatc
    17401 gaattgttgc caaaagtaac cgtattaatg gctatttcaa tgtaggagga gggaatccat
    17461 tccctaatga tactattgtg ggagcaaaat tcaatgatga gaagacaaaa catattgtta
    17521 ctcattatat ttctagagat gctcttaata aaacaataac cgttttaagt aagataattg
    17581 aagtttttga ggaacatttt gatagagcga taacatgtga gatgttttct gattcatcaa
    17641 cgtttgcttc tataaatttt tcggagtatg gtatttcaaa aagcaaattt caacagtatt
    17701 tgagagattc ttgctttatt gagaattttg gagttgagca cactactgtt tctgatattc
    17761 aaaattctat cgtgacattt tatgatgtcc atacagacat ttttagatta ctgaataaat
    17821 taaatattga tatttcagaa gctaatatca tgaatcagac cacggtcttg cttgatgaaa
    17881 aaaatattga attgctacta tcaaaagcgc cctatcttgt ctccatgatt gtggaagatt
    17941 tttctaagtt atctgtagat gatttttctt tagataataa tgatttaaaa ataaatcttc
    18001 catctccaat gaacgaacca gttgttggcg ttattgatac cttatttgac aaaagagttt
    18061 actttaatga gtgggtagaa tatcatgatt ttgtctcacc tgatattagc aaagatagcc
    18121 aagattacaa gcatgggaca gctgtgactt ctttaatcgt tgatggagcc aatttgaacc
    18181 ctaatctgga tgatggttgt ggaaatttta gagtgaggca ttttggtgtg tcactacaaa
    18241 gtggatttaa ttcatttaca atcataaaac agataaaaga gattgtttct cagaatgctg
    18301 atattaaggt ttggaatctt tctttagggt ccaatgatga aataagagaa aattttatct
    18361 ctgcagaggg agcattatta gacgaaattc aatttgagaa tgatgtaatt tttatcatag
    18421 ctgggacaaa tgcttcagta ataaatggga aacgcaaaag aataggtgct cctgctgatt
    18481 cacttaattc tataatagta aattctgttg attttaataa tcaatcagtg tcatattcac
    18541 gagagggtat tgttttatca ttctttgtta aaccagatgt gtcatattat ggaggaggaa
    18601 atggtgactt tataaatgtt tgtgaacctc taggattagg tcgtgtagct ggaacaagtt
    18661 ttgcggcacc ttttattgca aggaaaatgg cctatctcat tcatattatg ggacttagcc
    18721 gagaagaagc gaaggctttg ctaattgatg cagcaatacc ctggaatgat aagaaaacat
    18781 tcactgattt atctttgata ggaaatggta ttgttccaat aaaaatggat gatattttat
    18841 ctacacctga tgatgaaatt aaatttattg tgtcagatat ctctagggct tatgatacct
    18901 ataattatga ttttccagta cctatttcta gtgagagtta tccatatgta gctaaagcaa
    18961 caatgtgtta tttccctaac tgctcaagaa aacaaggggt tgattataca aatactgaga
    19021 tgcagcttac ttttggtagg ttaaagtcag acggtatcaa atcgataaat aaagacaacc
    19081 agcatgccga agatacccca ggatatgtga gagaaaacgc tgctagaaat atatttagga
    19141 aatgggataa tgtcaagcat attggagagt cgtttacttc tcgaaagaga gctaaagcaa
    19201 ttttaaatcc atctaatcct cagtggggga tgagtattaa aacaatcgaa cgtttgaaaa
    19261 gcggtgatgg acaaggagta cgttttggtg tagtagttac attaaaagaa ttaaatgggg
    19321 ttaatcgtat tgaagatttt attcagcaag ctgaattacg cggttggcta gttaatagat
    19381 tgcaagtaga agctcaagta gacctcttta atagtttaaa tgaagaaatt gaatttgaat
    19441 agtggatatt ttatccttat tttagatctt aggaacacaa gagggcaaag atatgaatat
    19501 tacttatata gttggaaatg gtttggattt gcaatatggt ttgaaaacaa gatataggga
    19561 tttctacgaa ttccaaaata aggtttatat aagtaggaca gagaacgagg aaaaatattc
    19621 aaatttcatt tatgagtctc tattttctga taaagtaaat gattatgaaa attggtcaga
    19681 ttttgaattg tcaattggta aattgacaaa agataacgac ctcatctcct caagtataga
    19741 aataaaggag aaatttatag atgattttag tgaagtagtt gatgatttaa gagaatatct
    19801 acgcatacaa caagaaaaaa atcttgagaa aggtaatgca attgacttta taagcactct
    19861 agatgatatg aggacctctc tccctgtaat taatcaacct gctatcgata aaaaatacaa
    19921 tgagaatcca catcaggacg acattgtaaa tatagtaaca cttaattata cacatgtaat
    19981 cgataaatta tataatgggt cagcaaaatc attcaggaat caattacgag ctaatcttta
    20041 taatttttat attgagccac caattcatgc acatgggacg gtggatgtct gcacggtttt
    20101 aggggttagt gatgaaatac aaatttcaaa tagtttagaa gaacaaaagg aatccctaat
    20161 aaaaagttta gttttaaaaa actatagaga aaatatggat gtaaagaata gtgatattat
    20221 aaaaaattct gacatcatta ttctctatgg ggtttctttg ggagaaactg ataggtatat
    20281 ctggagtcag attgctgaac gatcaatcag cggttctgtt cctgtcataa tttaccacta
    20341 tgtacctcat tttgatccgg ggaatcccat tagagcaaaa cgcctatata gaaatgtaga
    20401 agataaattc atacagaata gtggtataga cttagagtta gagaaaaaat taagagacaa
    20461 ccttattgtc gttattggta agactatttt tgatctaata gagaggtaat tttaaaaaac
    20521 aaaatggaaa catggcaaga gttaaaagtt acagtgaagc gtgaggggga ggagttggtt
    20581 tccaatctct tgattgagct gggagcgcaa ggtgttgcga ttgaagacag tctggactat
    20641 gtgggaaatg ttgaccgctt tggcgagatt ttcccagagg tggagcagca agaagaaatc
    20701 gtagtgaccg cctactaccc tgacacggtg gatgtgacag tggttgaggc ggatttgcag
    20761 gctcgtctag cagaattgac agattttatg gatttgggag agttaaaaat aggtacgact
    20821 gccttggctg aggaagactg ggcagacaac tggaagaaat actatgagcc agctcgtatc
    20881 actcatgatt tgaccattgt tccctcttgg acagactatg aggcgactgc gggagaaaaa
    20941 attatcaagc tggatcctgg catggctttt ggtactggaa cccacccaac taccaagatg
    21001 agcctttttg ccttggaaca ggttcttcgt ggtggcgaaa cggtgctaga tgtggggact
    21061 ggttcagggg ttctctctat tgccagctcg cttctggggg ctaaagaaat tttcgcctat
    21121 gacctggatg atgtggcggt tcgtgtggct caggaaaata ttgagctcaa ccctggcatg
    21181 gaaaatatcc atgtagcggc tggagatttg cttaagggtg tggaaattga ggcagatgtg
    21241 attgtggcta atatcttggc ggatatcctc attcatctaa tagacgatgc ctatcgtttg
    21301 gtcaaggacg aaggctacct gatcatgagt ggcattatca aggataagtg ggacatggtg
    21361 cgtgagtcgg ctgaatcggc tggatttttc ctcgaaaccc acatgattca aggggagtgg
    21421 aatgcctgtg tctttaagaa gaccaaggat atttcagggg tgattggagg ctagcatgca
    21481 gcagtatttt gtaaaaggca gtgctatctc tcctgtcact atcgaggaca aggaaatcag
    21541 taagcatatg tttcaggtta tgcgcttgaa agaagaggat gaggttacct tagtctttga
    21601 tgatggcatc aagcgcttgg cgcgcgtgct ggatatggaa aatcgtcagt ttgagttggt
    21661 ccaagaatta aatgacaatg tggaactacc agtccaagtg accatcgcat ctggatttcc
    21721 caagggagac aagctggagt tcatcgctca aaaagtaacc gaactgggtg ctagccaaat
    21781 ctgggccttt cctgcagact ggtcagttgc caagtgggat ggcaagaaat tgggtaaaaa
    21841 agttgaaaaa ctagaaaaaa ttgcccttgg agcagccgag caaagcaagc gtaatattgt
    21901 accaagtatt aaacttttcg agaaaaaagc agattttcta gctcagctgg accagtttga
    21961 ctctatcata gtagcctatg aagaatcagc taaagaagga gaagccgctg cgcttctgca
    22021 agcagtcact ggtcttgaaa caggagccaa actgctcttt atctttggtc cagaaggtgg
    22081 tctctcacct gcagaaatcg aaagttttga agctaaagga gcagttttgg caggcctagg
    22141 tcctcgtatt ttgcgagcag aaacagcacc gctttacgcc ttatcagccc ttagtgtttt
    22201 agtagaatta gagaaataag aggaagaaaa tggaacaaaa acaccgttca gaatttccag
    22261 agaaggaact ctgggactta acagccctat accaagaccg tgaggatttc ttgcgtgcaa
    22321 tcgagaaagc tcgtgaagac atcaaccaat ttagccgtga ttacaagggc aatcttcaca
    22381 cttttgagga tttcgagaag gcctttgcgg aattggaaca gatctacatt cagatgagcc
    22441 atattggcaa ctatgctttt atgcctcaga cgacggacta tagcaatgac gaatttgcca
    22501 atattgccca agctgggatg gaatttgaaa cagatgccag cgtagccttg accttctttg
    22561 acgatgcctt ggtggtagca gacgaggaag tcttggaccg tttgggtgaa ttgcctcact
    22621 tgacggcagc tattcgtcag gccaaaatca aaaaagccca ctatctaggg gctgatgtgg
    22681 agaaggcctt gaccaatctc ggtgaagttt tctatagtcc gcaggacatt tatactaaga
    22741 tgcgagctgg ggattttgaa atggctgact ttgaagccca tggcaagacc tataaaaaca
    22801 gctttgtcac ctatgagaat ttctaccaaa atcacgagga tgctgaggtt cgtgagaaat
    22861 ccttccgttc cttctcagag ggacttcgta agcaccaaaa tacggctgca gcagcctatc
    22921 tggctcaggt caagtctgaa aaactcttgg ctgatatgaa gggatacgac tctgtctttg
    22981 attatcttct agctgaacaa gaagtggacc gtgtcatgtt tgaccgccag attgacctca
    23041 tcatgaagga ctttgcacca gtcgctcaga gatacctcaa gcatgttgcc aaggtaaatg
    23101 gtcttgaaaa gatgaccttt gcagattgga aattggactt ggacagcgcc ctgaatcctg
    23161 aagtgactat tgacgatgcc tatgatttgg tcatgaagtc ggtagaacct ttggggcaag
    23221 aatattgtca ggaagttgct cgttaccaag aagagcgctg ggtggacttt gctgctaaca
    23281 gtggcaagga ttccggtggt tatgcggcgg acccatatcg cgtacaccct tatgtactca
    23341 tgagctggac aggccgtttg agcgatgtct ataccttgat tcatgaaatc gggcattctg
    23401 gtcaatttat cttttcagac aatcatcaaa gctatttcaa cgcccacatg tcgacctatt
    23461 atgttgaagc accgtcaacc ttcaatgaat tgctactcag tgattactta gagaaccagt
    23521 ctaatgaccc acgtcaaaaa cgcttcgctc tggctcatcg cttgacagac acctacttcc
    23581 ataatttcat cacccacctc ttggaagccg ccttccagcg taaggtgtat acattgattg
    23641 aagaagggga gacctttgga gcaagcaagc tcaacagcat tatgaaggaa gttttgacag
    23701 atttttgggg cgatgccatt gaaatcgacg acgatgcagc tttgacttgg atgcgccaag
    23761 ctcactacta tatgggcttg tatagttaca cttactctgc tggtcttgtc atctcgacag
    23821 ctggttacct tcatcttaaa aactcagaaa ctggagctga agactggctc aatctcctca
    23881 aatcaggtgg tagcaagaca ccacttgagt cagccatgat tatcggtgct gatatttcaa
    23941 cagacaaacc actccgtgat accatccaat tcttgtctga cacagttgac cagattatcg
    24001 cctacagtgc tgagttgggg gagtaagggg aatagaaaaa ttttctagaa tgatgtttat
    24061 gggcttgtta agcgtcattc tatttgtctt agttgtagct attttcaaaa atgtcgttga
    24121 aggtcgtgat gttaaatttg aacttactgt agaactggta ttgatagtta tttacgtcat
    24181 tttatatcag attgtattta attgagaatt caatattgag tcatttaaga ctgccttttt
    24241 gaacagttgc tagaaatgta gaggtattga ccatgtatca agatttacta agaaaaatag
    24301 cagaagaaaa accaaattat aaccaggagg aaatccagtg gttgcttgat catttgggag
    24361 atccttctcc agaaattcgc gatgaccttg tttttacaag ctttgctaga gggattcagg
    24421 aagagctatt tacacaggag caatttcatt tcattgctga aggggtttca tctgatggag
    24481 ggttagataa agagattgat aagataggcc tgccaacact tgaacgttct tttagggcgc
    24541 ttatttatgc aactctcttg tctgacgatg ccaaccagca atcgattttc tatcagagac
    24601 taaaagcaga aattcgtaat gtccttttaa atcaaggctt gcactatctt tcaaaagaaa
    24661 aggatacaac aggtttctca agtcagtatg gttgggttca ttcttttgca catggagccg
    24721 atttactgaa agaggtggtt tgtcatccag actttcctaa aaacagagtt catgaagtat
    24781 ttgatatact tggccaacta tttaaaagaa tgtcgattcg ctttacagat gatgaggatt
    24841 ggcgtttagc aagagtgatc tatgaaccta ttttacaagg gaagttggag caagaacaag
    24901 tagcttcttg gataaaaact gttgattttc cgatagaaga aagggaggat ttttccaaat
    24961 tttccaactt tagatcctgt ctggtggaag tctatgtcca acttgaccag agaaatagtt
    25021 tacaagatga gttgaaagaa gctatccagt cttttcaata ctagagatta gctaatagtt
    25081 ctatgatttt caaaaaattt ccaatcaatt ttcttgaaac cctttcctac ttttgataga
    25141 ctagtatcta gtttttgaaa aaaggagaaa gaaaatgaaa aaatttgttg ctgagttaat
    25201 cggtacgttc atgcttgtgt tcgttgggac aggagctgtt gtttttggaa atggttttga
    25261 tggccttggt caccttggaa tcgcctttgc ctttggtttg gcaatcgtgg tggcagccta
    25321 ctcaatcgga actgtttcag gtgctcactt gaacccggct gtttcgattg ctatgtttgt
    25381 aaacaaacgt ttgtcatctt cagaacttgt aaactacatc cttggtcagg ttgttggagc
    25441 tttcatcgct tctggcgctg tcttcttcct cttggctaac tcaggtatgt caactgctag
    25501 tcttggtgaa aatgccttgg caaacggtgt cactgtcttt ggtggtttct tgtttgaagt
    25561 catcgcaact ttcttgtttg tattggttat catgactgtg acttcagaaa gcaagggcaa
    25621 tggcccgatt gctggtttgg taatcggttt gtcattgatg gcgatgattc ttgtcggatt
    25681 gaagattact ggactttcag taaacccagc tcgtagcttg gcaccagctg tcttggtagg
    25741 cggcgcagcc cttcaacaag tttggatttt catccttgca ccaatcgctg gtggagttct
    25801 tgcagccctt gttgcaaaaa atttccttgg aacagaagaa taattgaaac tcaaaaagcc
    25861 ttgctcctca tcttgaggaa cagggctttt tcgtatgata ctcttcgaaa atctcttcaa
    25921 accacgtcag cttcaccttg tcgtaggtat ggtt
//
LOCUS       DAVHTH010000029        25088 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.029, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000029 DAVHTH010000000
VERSION     DAVHTH010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25088)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25088)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25088
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.029"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            <1..574
                     /locus_tag="VVR63_001233"
     CDS             <1..574
                     /locus_tag="VVR63_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU6129253.1"
                     /translation="KIPSRLYKIDTGKVLFDGVNINQIDKKILSQNLGVVPQDSFLLN
                     RSILDNITLKHEVTSQKIEEVCKAVQIYDEIMAMPMKFNTIISEMGSNISGGQRQRIA
                     LARALINNPSIVILDEATSALDTINEERITKYIQSQGCTQIIIAHRLSTIKDADIIFV
                     MKGGKIVESGNHKYLMDLGGEYYSLYTKRK"
     gene            587..757
                     /locus_tag="VVR63_001234"
     CDS             587..757
                     /locus_tag="VVR63_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6129254.1"
                     /translation="MKKVNEYVISTAASLGVMIGIVFAIFLDFPVEYAISLGLLNGIV
                     LGSLIFYKNNKN"
     gene            791..1519
                     /locus_tag="VVR63_001235"
     CDS             791..1519
                     /locus_tag="VVR63_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU6129255.1"
                     /translation="MAIVEIINLTKSFKDIEVIHNTSFYLNKGKVYGFVGPNGAGKTT
                     IIKMILGILKPDSGKITIFNQTVEQNSENILSRIGLVLGPSFYGHLDAYKNLKLIANM
                     KGLSLDTERLNEYLSMVGLKDVKKKKVKNFSMGMKQRLSIAASLLGSPEILIWDEPIN
                     GLDPQGVIEIRSLIRFLQEKKGITFLISSHILSELDKVISDIIIINYGKVEFFGSCHY
                     LLQKYNCRNLEEAYLACLAGGEYD"
     gene            1512..2249
                     /locus_tag="VVR63_001236"
     CDS             1512..2249
                     /locus_tag="VVR63_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6129256.1"
                     /translation="MIKLEFLKQKKSILWFVLIFPIILNVLLYIDLTFRYRGYLLVHQ
                     NELALSNWQLIFKEQTIFYFSELFYLVLSLIIYEVFAVEFKNDAWLTVISLPFRNKYT
                     INSKLLITVVYTFTFWLSDYISLYVIGKAIDNSLEIGLIFFLKTFTIQLISSLMIMLL
                     YFLTLVLIRKISGIIPIGIIMMILTISIYYNDYNFKIYLPFTYLSHAFRVTESQFYMI
                     LLSNIIIIVLFYILIRKLNERSFEMKL"
     gene            2262..2972
                     /locus_tag="VVR63_001237"
     CDS             2262..2972
                     /locus_tag="VVR63_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6129257.1"
                     /translation="MKLLKNELIKSKIFLFIIVDICIQILVILAIKTYILDISALYSE
                     LDYNKYWYILHTLIYMLMIFPIQILYQNLREALIEDNNNGWNIMVINTNNLVKIIYIK
                     VTINIVRCFICYFVYTIFSLIQLGGMGTDMLLTNIIFPNIMSFLLFLPIAIFMQICCI
                     RFDSILAKALPNILLILIVLITFQSDWNIFIPATYYYTEIQSTTNLGIKLLVCIWIMG
                     FEFFLLPKLIKLKEQNLV"
     gene            3514..3735
                     /locus_tag="VVR63_001238"
     CDS             3514..3735
                     /locus_tag="VVR63_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU6129258.1"
                     /translation="MYRRLRDLREDHDLTQKQIAKILSFTNSAYAKIERGEHTLTADV
                     LVTLSNFYDVSTDYLLELTDFPDKIRFRK"
     gene            4252..4505
                     /locus_tag="VVR63_001239"
                     /pseudo
     CDS             4252..4505
                     /locus_tag="VVR63_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558195.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            4633..5862
                     /locus_tag="VVR63_001240"
     CDS             4633..5862
                     /locus_tag="VVR63_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEU6129259.1"
                     /translation="MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSAL
                     QLVRNQGIFWIVSLILIALIYKLRLDFLRNERLIILVILIEMLLLFLARFIGISVNGA
                     YGWISVAGVTIQPAEYLKIIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWR
                     FVLLVLIGSLGIFPDLGNATILVLVSLIMYTVSGIAYRWFSTILALVSAASVFVLTTI
                     SLIGVETFSKIPVFGYVAKRFSAFFNPFADRADAGHQLANSYFAMVNGGWFGLGLGNS
                     IEKRGYLPEAHTDFVFSIVIEEFGFAGASLILALLFFMILRIILVGIRAENPFNAMVA
                     LGVGGMMLVQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVAFVLNIDASEKR
                     AKLYRELENQPMNLLLK"
     gene            5882..8578
                     /gene="ppc"
                     /locus_tag="VVR63_001241"
     CDS             5882..8578
                     /gene="ppc"
                     /locus_tag="VVR63_001241"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HEU6129260.1"
                     /translation="MSLQKLENYSNKSVVQEEVLILTELLEDITKNMLAPETFEKIIQ
                     LKELSTQEDYQGLNRLVTSLSNDEMVYISRYFSILPLLINISEDVDLAYEINHQNNID
                     QDYLGKLSTTIKLVAEKENAVEILEHLNVVPVLTAHPTQVQRKSMLDLTNHIHSLLRK
                     YRDVKLGLINKDKWYNDLRRYIEIIMQTDMIREKKLKVTNEITNAMEYYNSSFLKAVP
                     HLTTEYKRLAQAHGLNLKQAKPITMGMWIGGDRDGNPFVTAETLKQSALTQCEVIMNY
                     YDKKIYQLYREFSLSTSIVNVSKQVREMARQSKDNSIYREKELYRRALFDIQSKIQAT
                     KTYLIEDEEVGTRYETANDFYKDLIAIRDSLLENKGESLISGDFVELLQAVEIFGFYL
                     ASIDMRQDSSVYEACVAELLKSAGIHSRYSELSEEEKCDLLLKELEEDPRILSATHAE
                     KSELLAKELAIFKTARVLKDKLGDDVIRQTIISHATSLSDMLELAILLKEVGLVDTER
                     ARVQIVPLFETIEDLDHSEETMRKYLSLSLAKKWIDSRNNYQEIMLGYSDSNKDGGYL
                     SSCWTLYKAQQQLTAIGDEFGVKVTFFHGRGGTVGRGGGPTYEAITSQPLKSIKDRIR
                     LTEQGEVIGNKYGNKDAAYYNLEMLVSAAINRMITQKKSDTNTPNRYEAIMDQVVDRS
                     YDIYRDLVFGNEHFYDYFFESSPIKAISSFNIGSRPAARKTITEIGGLRAIPWVFSWS
                     QSRVMFPGWYGVGSSFKEFINKNPENIAILRDMYQNWPFFQSLLSNVDMVLSKSNMNI
                     AFEYAKLCEDEQVKAIYETILNEWQVTKNVILAIEGHDELLADNPYLKASLDYRMPYF
                     NILNYIQLELIKRQRRGELSSDQERLIHITINGIATGLRNSG"
     misc_binding    8661..8878
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            8991..9995
                     /locus_tag="VVR63_001242"
     CDS             8991..9995
                     /locus_tag="VVR63_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU6129261.1"
                     /translation="MKNKRLIGIIAALAVLVAGSLIYSSMNKSEAQNNKDEKKITKIG
                     VLQFVSHPSLDLIYKGIQDGLAEEGYKDDQVKIDFMNSEGDQSKVATMSKQLVANGND
                     LVVGIATPAAQGLASATKDLPVIMAAITDPIGANLVKDLKKPGGNITGVSDHNPAQQQ
                     VELIKALTPNVKTIGALYSSSEDNSKTQVEEFKAYAEKAGLTVETFAVPSTNEIASTV
                     TVMTSKVDAIWVPIDNTIASGFPTVVSSNQSSKKPIYPSATAMVEVGGLASVVIDQHD
                     LGVATGKMIVQVLKGAKPADTPVNVFSTGKSVINKKIAQELGITIPESVLKEAGQVIE
                     "
     gene            10064..10930
                     /locus_tag="VVR63_001243"
     CDS             10064..10930
                     /locus_tag="VVR63_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6129262.1"
                     /translation="MIVSIISQGFVWAILGLGIFMTFRILNFPDMTTEGSFPLGGAVA
                     VTLITKGVNPFLATLVAVGAGCLAGMAAGLLYTKGKIPTLLSGILVMTSCHSIMLLIM
                     GRANLGLLGTKQIQDVLPFDSDLNQLLTGLIFVSIVIALMLFFLDTKLGQAYIATGDN
                     PDMARSFGIHTGRMELMGLVLSNGVIALAGALIAQQEGYADVSRGIGVIVVGLASLII
                     GEVIFKSLSLAERLVTIVVGSIAYQFLVWAVIALGFNTSYLRLYSALILAVCLMIPTF
                     KQTILKGAKLSK"
     gene            10927..11685
                     /locus_tag="VVR63_001244"
     CDS             10927..11685
                     /locus_tag="VVR63_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6129263.1"
                     /translation="MTAIVELKNATKIVKNGFDEEKIILNDVSLEIFERDFITILGGN
                     GAGKSTLFNTIAGTLSLTSGTIRILGEELTKFSPEKRAKYLSRVFQDPKMGTAPRMTV
                     AENLLIAKFRGEKRGLLPRRLTSYKDEFQATIEKVGNGLEKHLNTPIEFLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALNPKTSVALMELTDEFVKKDQLTALMITHHMEDALKY
                     GNRLIVMKEGRIIQDLNQEEKAKMKISDYYQLFE"
     gene            11775..13535
                     /gene="dnaG"
                     /locus_tag="VVR63_001245"
     CDS             11775..13535
                     /gene="dnaG"
                     /locus_tag="VVR63_001245"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HEU6129264.1"
                     /translation="MVDKQVIEEIKNNANIVEVIGDVISLQKAGRNYLGLCPFHGEKT
                     PSFNVVEDKQFYHCFGCGRSGDVFKFIEEYQGVPFIEAVQILGQRVGIEVEKPLYSEQ
                     KPASPHQALYDMHEDAAKFYHAILMTTTMGEEARNYLYQRGLTDEVLKHFWIGLAPPE
                     RNYLYQRLSDQYREEDLLDSGLFYLSDANQFVDTFHNRIMFPLTNDQGKVIAFSGRIW
                     QKTDSQTSKYKNSRSTAIFNKSYELYHMDRAKKSSGKASEIYLMEGFMDVIAAYRAGI
                     ESAVASMGTALSREHVEHLKRLTKKLVLVYDGDKAGQAATLKALDEIGDMPVQIVSMP
                     DNLDPDEYLQKNGPEDLAYLLTKTRISPIEFYIHQYKPENSENLQAQIEFLEKIAPLI
                     VQEKSIAAQNSYIHILADSLASFDYTQIEQIVNESRQVQRQNRMEGISRPTPITMPIT
                     KQLSAIMRAEAHLLYRMMESPLVLNDYRLREDFAFATPEFQVLYDLLGQYGNLPPEVL
                     AEQTEEVERAWYQVLAQDLPAEISPQELSEVEMTRNKALLNQDNMRIKKKVQEASHVG
                     DTDTALEELERLISQKRRME"
     gene            13538..14647
                     /gene="rpoD"
                     /locus_tag="VVR63_001246"
     CDS             13538..14647
                     /gene="rpoD"
                     /locus_tag="VVR63_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HEU6129265.1"
                     /translation="MATKQKEVTTFDVQVAEFIRNHKQKGTATDDEINASLVIPFTLD
                     ADGIEDLLQRIQDAGISITDNEGNPSARVLSNEEEPELSDEDLIGSTSAKVNDPVRMY
                     LKEIGVVPLLTNEEEKELALAVEAGDIEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMDMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRIVLREQLDEILDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRQPSRSKPLRDFIED"
     gene            14661..14990
                     /locus_tag="VVR63_001247"
     CDS             14661..14990
                     /locus_tag="VVR63_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEU6129266.1"
                     /translation="MAYTEEQIENIKTRILTALEEVIDPELGIDIVNLGLIYEIRFDG
                     DTGQTEIDMTLTTMGCPLADLLTDQIYDAMIEVPEVTDTEVKLVWYPAWTVEKMSRYA
                     RIALGIK"
     gene            15105..16148
                     /gene="cpoA"
                     /locus_tag="VVR63_001248"
     CDS             15105..16148
                     /gene="cpoA"
                     /locus_tag="VVR63_001248"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosylglucosyldiacylglycerol synthase"
                     /protein_id="HEU6129267.1"
                     /translation="MEKKKLRINMLSSSEKVAGQGVSGAYRELVRLLHRAAKDQLIVT
                     ENLPIEADVTHFHTIDFPYYLSTFQKKRSGRKIGYVHFLPATLEGSLKIPFFLKGIVK
                     RYVFSFYNRMEHLVVVNPMFIEDLVAAGIPREKVTYIPNFVNKEKWHPLPQEEVVRLR
                     TDLGLSDNQFIVVGAGQVQKRKGIDDFIRLAEELPQITFIWAGGFSFGGMTDGYEHYK
                     KIMENPPKNLIFPGIVSPERMRELYALADLFLLPSYNELFPMTILEAASCEAPIMLRD
                     LDLYKVILEGNYRATAGREEMKEAILEYQANPAALKDLKEKAKNISREYSEEHLLQIW
                     LDFYEKQAALGRK"
     gene            16164..17489
                     /locus_tag="VVR63_001249"
     CDS             16164..17489
                     /locus_tag="VVR63_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEU6129268.1"
                     /translation="MRIGLFTDTYFPQVSGVATSIRTLKTELEKQGHAVFIFTTTDKD
                     VNRYEDWQIIRIPSVPFFAFKDRRFAYRGFSKALEIAKQYQLDIIHTQTEFSLGLLGI
                     WIARELKIPVIHTYHTQYEDYVHYIAKGMLIRPSMVKYLVRGFLHDVDGVICPSEIVR
                     DLLSDYKVKVEKRVIPTGIELAKFERPEIKQENLKELRSKLGIQDGEKTLLSLSRISY
                     EKNIQAVLAAFADVLKEEDKVKLVVAGDGPYLNDLKEQAQNLEIQDSVIFTGMIAPSE
                     TALYYKAADFFISASTSETQGLTYLESLASGTPVIAHGNPYLNNLISDKMFGTLYYGE
                     HDLAGAILEALIATPDMNEHTLSEKLYEISAENFGKRVHEFYLDAIISNNFQKDLAKD
                     DTVSQRIFKTVLYLQQQVVAVPVKGSRRMLKASKTQLISMRDYWKDHEE"
     gene            17520..17696
                     /locus_tag="VVR63_001250"
     CDS             17520..17696
                     /locus_tag="VVR63_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEU6129269.1"
                     /translation="MRSGRDKKIAGVCAGVAHYLDMDPTIVQVIWGVLTCCYGAGIVA
                     YIILWIIAPVATDY"
     gene            17755..17889
                     /locus_tag="VVR63_001251"
     CDS             17755..17889
                     /locus_tag="VVR63_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HEU6129270.1"
                     /translation="MAFGDNGNRKKTMFEKITLFIVIIMLVASLLGIFATAIGALSNL
                     "
     gene            17953..19263
                     /gene="obgE"
                     /locus_tag="VVR63_001252"
     CDS             17953..19263
                     /gene="obgE"
                     /locus_tag="VVR63_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HEU6129271.1"
                     /translation="MSMFLDTAKIKVKAGNGGDGMVAFRREKYVPNGGPWGGDGGRGG
                     NVVFVVDEGLRTLMDFRYNRHFKADSGEKGMTKGMHGRGAEDLRVRVPQGTTVRDAET
                     GKVLTDLIEHGQEFIVAHGGRGGRGNIRFATPKNPAPEISENGEPGQERELQLELKIL
                     ADVGLVGFPSVGKSTLLSVITSAKPKIGAYHFTTIVPNLGMVRTQSGESFAVADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHIIDMSASEGRDPYEDYLAINKELESYNLRLME
                     RPQIIVANKMDMPESQENLEEFKKKLSENYDEFEELPAIFPISGLTKQGLATLLDATA
                     ELLDKTPEFLLYDESDMEEEAYYGFDEEEKAFEISRDDDATWVLSGEKLMKLFNMTNF
                     DRDESVMKFARQLRGMGVDEALRARGAKDGDLVRIGKFEFEFVD"
     gene            19273..19431
                     /locus_tag="VVR63_001253"
     CDS             19273..19431
                     /locus_tag="VVR63_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6129272.1"
                     /translation="MGDKPISFRDADGNFVSAADVWNEKKLEELFNRLNPNRALRLAR
                     TKKENPSQ"
     gene            20518..21777
                     /locus_tag="VVR63_001254"
     CDS             20518..21777
                     /locus_tag="VVR63_001254"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEU6129273.1"
                     /translation="MRKIVINGGLPLQGEITISGAKNSVVALIPAIILADDVVTLDCV
                     PDISDVASLVEIMELMGATVKRYDDVLEIDPRGVQNIPMPYGKINSLRASYYFYGSLL
                     GRFGEATVGLPGGCDLGPRPIDLHLKAFEAMGATASYEGDNMKLSAKDTGLHGASIYM
                     DTVSVGATINTMIAAVKANGRTIIENAAREPEIIDVATLLNNMGAHIRGAGTNIIIID
                     GVERLHGTRHQVIPDRIEAGTYISLAAAVGKGIRINNVLYEHLEGFIAKLEEMGVRMT
                     VSEDSIFVEEQSNLKAINIKTAPYPGFATDLQQPLTPLLLRANGRGTIVDTIYEKRVN
                     HVFELAKMDADISTTNGHILYTGGRDLRGASVKATDLRAGAALVIAGLMAEGKTEITN
                     IEFILRGYSDIIEKLRNLGADIRLVED"
     gene            21793..22344
                     /locus_tag="VVR63_001255"
     CDS             21793..22344
                     /locus_tag="VVR63_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6129274.1"
                     /translation="MNIWTKLAMFSFFETDRLYLRPFFFSDSQDFREIASNPENLQFI
                     FPTQASLEESQYALANYFMKSPLGVWAICDQKNQQMIGSIKFEKLDEIKKEAELGYFL
                     RKDAWSQGFMTEVVRKICQLSFEEFGLKQLFIITHLENEASQRVALKSGFSLFRQFKG
                     SDRYTRKMRDYLEFRYVKGEFNE"
     gene            22337..23614
                     /locus_tag="VVR63_001256"
     CDS             22337..23614
                     /locus_tag="VVR63_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEU6129275.1"
                     /translation="MSKHQEILSYLEELPVGKRVSVRSISNHLGVSDGTAYRAIKEAE
                     NRGIVETRPRSGTIRVKSQKVAIERLTFAEIAEVTSSEVLAGQEGLEREFSKFSIGAM
                     TEQNILSYLHDGGLLIVGDRTRIQLLALENENAVLVTGGFQVHDDVLKLANQKGIPVL
                     RSKHDTFTVATMINKALSNVQIKTDILTVEKLYRPSHEYGFLRETDTVKDYLDLVRKN
                     RSSRFPVINQHQVVVGVVTMRDAGDKSPSTTIDKVMSRSLFWVGLSTNIANVSQRMIA
                     EDFEMVPVVRSNQTLLGVVTRRDVMEKMSRSQVSALPTFSEQIGQKLSYHHDEVVITV
                     EPFMLEKNGVLANGVLAEILTHMTQDLVVNSGRNLIIEQMLIYFLQAVQIDDILRIQA
                     RIIHHTRRSAIIDYDIYHGHQIVSKANVTVKIN"
     gene            23630..24490
                     /locus_tag="VVR63_001257"
     CDS             23630..24490
                     /locus_tag="VVR63_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HEU6129276.1"
                     /translation="MITLKSAREIEAMDKAGDFLASIHIGLRDLIKPGVDMWEVEEYV
                     RRRCKEENFLPLQIGVDGAMMDYPYATCCSLNDEVAHAFPRHYILKDGDLLKVDMVLG
                     GPIAKSDLNVSKLNFNNVEQMKKYTQSYSGGLADSCWAYAVGTPSEEVKNLMDVTKEA
                     MYKGIEQAVVGNRIGDIGAAIQEYAESRGYGVVRDLVGHGVGPTMHEEPMVPNYGIAG
                     RGLRLREGMVLTIEPMINTGDWEIDTDMKTGWAHKTIDGGLSCQYEHQFVITKDGPVI
                     LTSQGEEGTY"
     gene            24871..>25088
                     /locus_tag="VVR63_001258"
     CDS             24871..>25088
                     /locus_tag="VVR63_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HEU6129277.1"
                     /translation="MNDEASKQLTDARFKRLVGVQRTTFEEMLAVLKTAYQLKHAKGG
                     RKPKLSLEDLLMATLQYVREYRTYEEIAA"
BASE COUNT         7859 a         4118 c         5403 g         7708 t
ORIGIN      
        1 aaaaatacca tcaagattat ataagattga tacaggaaaa gttttatttg atggtgtaaa
       61 tattaatcaa atagataaaa aaatattaag tcaaaattta ggagtagttc cacaggattc
      121 atttttattg aaccgaagta ttcttgataa tataacttta aagcacgaag ttacttcaca
      181 aaagatagag gaagtttgta aagcagttca aatctatgat gaaatcatgg ctatgccgat
      241 gaaatttaat actatcatct cagagatggg gtcaaatatt tcaggtgggc aaaggcaacg
      301 gatagcactg gcacgtgcat taataaataa tcctagtatt gtaattttag atgaagcaac
      361 tagtgcatta gacactatta atgaggaaag aataacaaag tatatacaaa gtcagggttg
      421 tactcaaata attatagctc atagattgtc aacgattaag gatgcggata ttatttttgt
      481 aatgaaaggt ggtaagattg ttgagtcagg aaatcataag tacttaatgg atcttggtgg
      541 agagtactac agcttatata caaaaaggaa atgaggtgta aagaaaatga agaaagtaaa
      601 tgaatatgta atttcaacag cagcctcact aggggtgatg attggaatag tatttgcaat
      661 ttttttagat tttccagttg aatatgctat ttctttaggt ttgttgaatg gaatagtatt
      721 gggttcgctg attttttaca aaaacaataa gaattaagca taattttttg ctgtaaacta
      781 aggagtagag atggctatag ttgaaattat aaatctaaca aaaagcttta aagatattga
      841 agttattcat aacacttcat tttatttaaa taagggaaaa gtatatggtt ttgttggacc
      901 aaatggggct ggaaaaacta caattatcaa aatgattcta gggattttaa aaccagattc
      961 tgggaaaata actattttta atcaaaccgt agaacagaat tccgaaaata tattatctag
     1021 gataggatta gttttgggac cttcatttta tggtcatctt gatgcttata aaaatttgaa
     1081 gttaatagca aatatgaaag ggcttagttt agatactgaa agacttaatg aatatctatc
     1141 aatggtagga ttaaaagatg ttaaaaagaa aaaagtgaaa aatttttcaa tgggcatgaa
     1201 acaacgtcta agtatagctg catcattgtt aggtagtcca gaaatattaa tttgggatga
     1261 accaatcaat ggacttgatc cacagggtgt aattgaaatt agaagtttaa tccgttttct
     1321 acaggagaaa aaaggtatta catttttaat atcaagtcat attcttagtg aactggataa
     1381 agtgatatct gatattataa ttataaatta tgggaaagtt gaattttttg gttcttgcca
     1441 ctacctttta caaaagtata attgtcgaaa tctggaagaa gcctacttag cttgtttagc
     1501 tggaggtgaa tatgattaaa ttagagtttc taaagcagaa aaaaagcatc ttatggtttg
     1561 ttcttatttt tccaataatt ctgaatgttt tgttatatat agacttaact tttaggtatc
     1621 gaggttattt attggtgcat caaaatgaac ttgctttatc taattggcag ttaattttta
     1681 aagaacaaac aatattttat ttttctgaac tattttattt agttctatct ttaataattt
     1741 acgaagtgtt tgcagtagaa tttaaaaatg atgcatggtt aaccgtaatt tcattgccat
     1801 ttagaaacaa gtacacaata aattctaaat tactcattac agtggtttac acatttactt
     1861 tttggttgtc tgattatatt agcttatacg ttattgggaa ggctattgat aacagtttag
     1921 agattggttt gattttcttt ttaaaaacat ttaccattca attaatttcc tcgttgatga
     1981 taatgttatt atattttcta actttagtac ttataaggaa aatttctgga ataataccaa
     2041 ttggtattat aatgatgatt ttaacaatta gcatatacta caacgattat aattttaaga
     2101 tttacttacc atttacttat ctttctcatg cttttagagt gactgaaagt caattttata
     2161 tgattttact atctaatata ataatcatcg tactttttta tatattaatt cgtaaattga
     2221 acgaaagaag ttttgagatg aaactttaat aggtaataaa aatgaagtta cttaaaaatg
     2281 aattgattaa gagtaaaata tttttattta ttattgttga catctgtatt cagattctag
     2341 tcattctagc tataaaaaca tatattttag atatttcggc actatactca gagcttgatt
     2401 ataataagta ttggtatatt ttacacactt taatatatat gctaatgatt tttcctatac
     2461 aaattttgta tcaaaatcta agagaggcat tgattgaaga taataataat ggttggaata
     2521 tcatggtgat taacactaat aatctcgtga aaatcatcta tataaaagta acgataaata
     2581 tcgtgagatg ttttatttgt tattttgttt atacaatttt ttctttaatt caattaggtg
     2641 gtatgggaac tgatatgtta ttaaccaata taatatttcc caatataatg tcatttcttt
     2701 tatttttacc tatagctatc tttatgcaaa tttgctgtat aagatttgat tccattttag
     2761 caaaggcctt acctaatatt ttgctgatac ttattgtttt aatcacgttt cagagtgatt
     2821 ggaatatatt tatacctgca acttattatt atacagaaat tcagtcaact acaaacttag
     2881 gtattaaatt attagtttgt atctggatta tgggatttga atttttcctt cttccaaaac
     2941 taataaaatt gaaagaacaa aatctagttt aaatgttgct cgaaaattaa ataattgaat
     3001 acgattaaca atgaaacaat acaacgtgag tcatgacttc aaagtaattg attttatgat
     3061 tctggtttct tacgcttaat taagcaagtt gtattcactt tatcaaattg ttattactct
     3121 aaaaagcgtc taacagctat agagtgtctg tttgcttctc tttactttta ttttaaataa
     3181 ttcattaacc ttccgtaagt gcccaataat aaggtgtgtt gaagaagtct gagataaaat
     3241 agttctcagt cacaaaaaag ctatagattc ccattggtga acagctccct gtcaagtaga
     3301 cagtaaaata atataaaatc ttaagcgacc tgattcctga attccagtgg agtcaggttg
     3361 ttttttaacc gtctttctta atattgtctt acctataata gatatgctta tgagatatgt
     3421 ttaataaatt aattttagtt caaaatgtcc agttaggaca ctttgaatga tttcttagtt
     3481 ttatatatta tacttttctc aggagaaagc tagatgtaca gacgtttgag agatttgagg
     3541 gaagatcacg atttgaccca aaaacaaata gctaaaatac tttcgtttac aaactcagct
     3601 tatgctaaaa ttgaacgggg tgagcatacg ttaacagcag atgtattggt aactctctca
     3661 aacttttacg atgtcagtac agactaccta ttggaattga cagattttcc tgataaaatt
     3721 cgctttagaa aataatctcc tcaatttcat agagtgtgaa aatgaggaga ttttttattt
     3781 gttctttgaa aattaaatag tccaaaatgg tactttcctc atttgtggag caaatttgaa
     3841 tggctcgcca tgataagagc gattttaaaa ccatcaataa aatagagcga tactttatat
     3901 gccatgatac aaatgatata caatgatact tctgaccgtt caggctgcca tcgtaaaaga
     3961 gcagcaagtg aaattcttat gatgacttca tcagtcatgc cacgttaaat gtgtgagttt
     4021 gttagagaaa cgcaattaat cctcaaaagg ttccccgaac cttttgagtt ccacagacgc
     4081 atcacgtgga gtgtgtaagc ttgttgctaa aagcgtaaaa accttggaac gaaaggaata
     4141 atagacttcc tgcgaaacaa aaatacaata caataaaact atggatgatg aagcaagtaa
     4201 acaattaagc gatagccgtt tcaagagcct tgtaggtgtt cagcgcacga gatgttagct
     4261 gtgttaaaaa cagcttatca acgcaacgta aacgcgcaaa aggtggacga aaaaccaaat
     4321 taagcctaga cgatctcctc atggtaacta ttcaatacat gcgagaatag cgcacttatg
     4381 aacaaattgc ggctgatttt ggcattcacg aaagcaactt aatccgtcgg agccaatggg
     4441 ttgaagtaac tcttgttcaa aatggtttta cgatttcaaa ttctgcccta attatgaaaa
     4501 acagtaaaat tcgaaggatt gtaaggtaag agtttttttc tttctgaaaa aatggtataa
     4561 tagcaatcaa aactagaaaa taaaacggaa tttggaacag atttgtctgt atcctagtag
     4621 agtggtgatg ctatgaagat tagtaagagg cacttattaa attattccat cttgattccc
     4681 tacttgcttt tatctatttt gggcttgatt gtggtctatt cgaccaccag tgctatttta
     4741 attgaagaag gcaagagcgc cttgcagttg gttcgaaacc aaggaatctt ttggattgtt
     4801 agtttgatac tgattgcctt aatttataaa ttgagactag attttttgag aaatgagcga
     4861 ctaatcattt tagttatatt aatagaaatg cttttattgt tcttggctcg ttttattggt
     4921 atttccgtaa acggggcata cggttggatt tcggttgcag gagtaactat tcagccagct
     4981 gagtacttaa aaatcattat tatttggtat ttagctcacc gattctccaa acagcaagaa
     5041 gaaatagcta cttatgattt tcaagttttg actcaaaatc aatggcttcc ccgtgctttt
     5101 aatgattggc gattcgttct cctagttctg attggaagtt tgggaatttt ccctgattta
     5161 ggaaatgcga ctattttagt cttggtttcc ttgattatgt atacagttag tggaatcgct
     5221 tatcgctggt tttcaaccat tctggcgctc gtatctgccg cttctgtctt tgtcttgacc
     5281 actatcagcc taatcggtgt tgagaccttt tcaaaaattc cagtatttgg ctatgtagcc
     5341 aagcgcttta gtgccttttt taatcctttt gccgatcgtg ctgatgcagg tcaccagtta
     5401 gctaattctt attttgccat ggtcaatggt ggttggtttg gtctaggtct tggaaactcg
     5461 attgaaaaac gaggttattt gccagaagct catacagact ttgtcttttc tatcgtgatt
     5521 gaagaatttg gctttgctgg tgccagtctt attttagctc tcttgttttt catgattttg
     5581 cggattatct tggtcggtat tcgagcggag aatcctttca atgccatggt tgcactcggt
     5641 gtcggaggga tgatgttggt tcaggtattt gtcaatatcg gagggatttc gggcttgatt
     5701 ccatctacag gagtaacctt ccccttctta tcccagggtg gaaatagtct tctagtctta
     5761 tcagtggcag tagcctttgt cttaaatatt gatgccagtg aaaaacgcgc taagttgtac
     5821 cgagaattgg aaaatcaacc aatgaacctt ctgttgaagt aggataaaga aaggatagtt
     5881 tatgtctctt caaaaattag aaaattatag taataaaagt gttgtgcaag aagaagtctt
     5941 gattctaaca gaattactgg aagatattac taaaaatatg cttgccccag agacctttga
     6001 aaaaataata cagttgaaag aattatcaac gcaggaagat tatcaaggtc taaaccgtct
     6061 agtgactagc ttatcaaatg atgaaatggt ctatatttca cgctatttct ctatcttacc
     6121 tcttttgatc aatatttcag aggatgtgga tttagcttat gaaatcaatc atcaaaataa
     6181 tattgatcag gactatttag gtaaattatc tacaacgatt aaattggtag cagaaaagga
     6241 aaatgccgtt gagatcctag aacacttgaa tgttgtccct gttttgacag cccatccaac
     6301 acaagtgcaa cgcaaaagta tgttggattt aacaaatcat attcatagtc ttttgcgtaa
     6361 ataccgtgat gttaagttgg ggttgatcaa taaagataaa tggtacaatg atttgcgtcg
     6421 ttacatcgaa attatcatgc agacagacat gattcgtgag aaaaaattaa aagtgactaa
     6481 cgaaatcacg aatgctatgg aatattataa cagctccttt ttgaaagctg tacctcattt
     6541 gacgacggag tataagcgct tagcgcaagc gcatggtctg aatttaaaac aggctaaacc
     6601 aatcaccatg ggtatgtgga taggtggtga ccgtgatgga aatccatttg ttacagcaga
     6661 gaccttgaag cagtctgcac tcactcaatg tgaagtcatc atgaactact atgataaaaa
     6721 gatttaccaa ctttatcgtg aattttctct ttcaactagc attgtcaacg tcagcaagca
     6781 agtcagagaa atggctcgtc aatccaagga taactcgatt taccgcgaaa aagagcttta
     6841 ccgtcgtgcc ttgtttgata ttcaatcaaa aattcaggca actaaaacct atctgattga
     6901 ggatgaagaa gttgggactc gttatgaaac cgccaatgat ttctacaagg atttgattgc
     6961 cattcgagat tctctactag aaaataaggg tgagtccttg atttcaggtg attttgtgga
     7021 attattgcag gcagtagaga tatttggttt ttacctagca tcaattgata tgcgacaaga
     7081 ctctagcgtc tatgaagcct gtgtggcaga actcttgaaa tcagcaggaa ttcattctcg
     7141 ttatagcgag ttgagcgaag aagaaaagtg tgaccttctc ttgaaagaat tagaagaaga
     7201 tccccgaatt ctttctgcga ctcacgcaga aaaatcagaa ttattagcaa aagaattagc
     7261 tatttttaag acggctcgtg ttttgaaaga taagttggga gatgatgtca tccgtcagac
     7321 catcatttca catgcaacca gcctttctga tatgctagaa ttagctattc tgttaaaaga
     7381 agtaggactg gtggatacgg aaagggcgcg tgttcagatt gttccccttt ttgaaacaat
     7441 tgaagacttg gatcattcag aagaaacaat gagaaaatat ctttctctta gccttgccaa
     7501 aaaatggatt gactcacgaa ataactacca agaaatcatg cttggctact ctgacagtaa
     7561 taaagatggc ggttacttgt catcatgttg gaccctctac aaggctcaac aacaattgac
     7621 tgctattgga gatgaatttg gcgttaaggt taccttcttc catggtcgtg gtggtactgt
     7681 cggtcgtggt ggtgggccaa cctatgaagc cattacatct caaccgctca agtctatcaa
     7741 ggatcgtatc cgcttgacgg agcagggtga agtaattggg aataaatacg gtaacaaaga
     7801 cgccgcttac tataaccttg aaatgctagt atcggcagct attaaccgta tgattactca
     7861 gaagaagagc gataccaata ccccaaatcg ttatgaagcc attatggatc aagtagtgga
     7921 ccgtagttac gatatctacc gtgatttggt ctttggtaat gagcatttct atgattattt
     7981 cttcgagtca agtccaatca aggctatttc aagttttaat attggttctc gtccagccgc
     8041 tcgtaagact attactgaaa tcggtggttt gcgtgccatc ccttgggtat tctcatggtc
     8101 acagagtcgt gttatgttcc ctggatggta cggggttggt tcaagcttca aggaatttat
     8161 caataaaaat ccagagaata ttgctatctt acgagatatg taccaaaatt ggcctttctt
     8221 ccaatcgctt ctttcaaatg ttgatatggt tttgtcaaaa tcaaatatga atattgcttt
     8281 tgaatatgct aaactttgtg aagacgagca agttaaggcc atctatgaga ctattttaaa
     8341 tgaatggcaa gttactaaga acgttatctt ggctattgaa ggacatgacg aactcttagc
     8401 tgacaatcca tatctaaaag ctagtctgga ttaccgtatg ccttacttta atattctcaa
     8461 ctatattcag ttagagttga ttaaacgcca acgtcgtgga gaattgtcca gtgatcaaga
     8521 acgattgatt catatcacca tcaacggaat tgcgacagga ttgcgtaatt caggttgata
     8581 attttcaaga gtgaatgcta aaagtgaata tcaaaaaaat tctaatagac tattgacaag
     8641 tagtttaaaa atgatataat ttaaccattc agaaaagtaa tcatacaaac tttttagaga
     8701 gtctgtggta gctgaaaaca gataagtggc gatgatgaaa attgggctga atgctattta
     8761 gaatttgaaa ttataaaaat tcggtaagca caccttacag tgcatctcgt tattgcgaga
     8821 ctgagcgata gggaaattcc ctataattga ggtggtaccg cgcatcgacg tcctcacaca
     8881 agttttttgt gtgaggattt ttttgatgga ggttagtatg gaaagaaaac gatggcgtcg
     8941 cttgtttaga taagtgaaat atgttaaagg aaataaaaag gagaaacaga atgaaaaata
     9001 aacgtttaat tggaattatt gctgcattag cagtcttagt agcaggaagc ttgatttatt
     9061 cttcaatgaa taaatcagaa gctcagaata ataaggatga gaagaaaata actaagattg
     9121 gtgtgcttca atttgtgagc catccatccc ttgatttgat ttataaaggg atccaagatg
     9181 gacttgcaga agaaggatat aaagatgatc aagttaaaat tgattttatg aactcagaag
     9241 gtgaccaaag taaggttgcg acaatgagta aacaattggt tgcaaatggg aatgaccttg
     9301 tggttggtat cgcaacacca gcagcccaag ggttggctag tgcaacaaaa gacctaccgg
     9361 ttatcatggc cgctattaca gacccaattg gtgctaactt ggttaaagat ttgaaaaaac
     9421 caggtggcaa cattacaggg gtatctgacc acaatccagc tcaacaacaa gttgaactca
     9481 tcaaggctct gacaccgaat gtgaaaacaa tcggagctct ttactcaagt agcgaagaca
     9541 attcaaaaac acaggtcgaa gaatttaagg cttatgctga aaaagcaggt ctgacagtgg
     9601 aaacatttgc agttccttca acaaatgaaa ttgcctcaac tgtcactgtt atgactagca
     9661 aggtagatgc tatttgggtt ccaattgata acaccattgc atcaggattt ccaacggttg
     9721 tctctagcaa tcaaagttct aagaaaccaa tttatcccag tgcgacagct atggtagaag
     9781 taggtggttt ggcatcagtt gtaattgacc aacatgacct tggtgtggca acaggtaaaa
     9841 tgattgtgca agtcttgaaa ggtgcaaaac cagccgatac cccagtcaat gtcttttcaa
     9901 ctggtaagtc agtcatcaat aaaaaaatag cacaagaact aggtattact attcctgagt
     9961 ctgttctcaa agaagcagga caagtcatcg aataaataag gtagggagga ggagactctt
    10021 cccatttttt aaaaagatga atatagaaag gattaaataa aatatgattg tttccattat
    10081 ttctcaagga tttgtctggg ctattctagg tctgggaatc tttatgacat ttaggatttt
    10141 aaactttcca gatatgacga cagaaggttc cttccctctt gggggagctg ttgctgtcac
    10201 tttgataacc aaaggcgtga acccattttt agcgacactt gttgctgtag gagcaggttg
    10261 tttggctgga atggcagcag gccttcttta tacaaaaggg aagatcccaa ccttgctatc
    10321 agggattttg gtgatgactt cttgtcactc aatcatgctc ttgattatgg gacgtgcgaa
    10381 tttaggcctg cttggaacca agcaaattca ggatgttttg ccttttgatt cggatttgaa
    10441 tcaactcttg acaggtctca tctttgtgag tattgttatt gctctcatgc tctttttctt
    10501 ggacactaaa ctcggacaag cctatattgc tacaggggat aatcctgata tggctagaag
    10561 tttcgggatt catactggac gcatggagct catgggcttg gtcttatcaa atggtgtgat
    10621 tgcccttgca ggtgccctca ttgctcagca agaaggttat gccgatgtgt ctcgagggat
    10681 cggggttatc gttgtggggc ttgcaagttt gattattgga gaagttattt tcaagagttt
    10741 gagcttggca gagcgtttgg ttactatcgt tgtaggttct atcgcttatc aatttttagt
    10801 gtgggcagtt atcgcacttg gctttaatac aagttacctt cgtttataca gtgccttgat
    10861 tttagcagtc tgcctcatga ttccaacatt taagcaaaca atcttgaaag gagccaagtt
    10921 aagcaaatga cagcaattgt agaattaaaa aatgcaacca aaatcgttaa aaatggcttt
    10981 gatgaagaaa agattatttt aaatgatgtt tccttagaaa tttttgaacg ggactttatc
    11041 acgattttgg gcggaaatgg tgctggaaaa tcaaccctct ttaacactat agcagggacc
    11101 ttatcactaa ctagtggaac tatccgtatt ttaggtgaag aactcactaa gttttcaccc
    11161 gagaagcgtg ccaagtacct gtctcgtgtc ttccaagatc caaagatggg gacagctccc
    11221 cgtatgacgg tcgctgaaaa tcttttaatc gccaagtttc gtggtgaaaa gcgtggattg
    11281 ttaccacgac gcttgactag ctataaggat gaatttcagg caaccattga aaaagtagga
    11341 aatggtcttg agaaacactt gaatacaccg attgagttct tatcaggtgg acaaagacag
    11401 gctttgagtc tcttgatggc aaccttgaag cgacctgaat tactcctgtt agatgagcat
    11461 actgctgccc tgaatccaaa gactagtgtt gctttgatgg aattgacaga tgaatttgtt
    11521 aagaaagatc agctaacagc ccttatgatt actcatcata tggaagatgc tctcaaatac
    11581 ggcaatcgct tgattgtcat gaaagaagga cggattatcc aagatttaaa ccaagaagaa
    11641 aaagcaaaaa tgaaaatctc tgattattat caactctttg aataaagtag ggaaaatgag
    11701 tgaaatggtt tacttttttt ctgaaataaa gtatactata taaagtaaac tatgataaca
    11761 tggaggtatt gtgtatggtt gacaaacaag tcattgaaga aatcaaaaac aatgccaaca
    11821 ttgtggaagt cataggagat gtgatttctt tacaaaaggc aggacggaac tatctagggc
    11881 tctgtccttt tcatggtgaa aaaacacctt ctttcaacgt tgtagaggat aagcagtttt
    11941 atcactgttt cggttgtggt cgctcaggtg atgtctttaa gttcatcgag gagtaccaag
    12001 gggttccctt tatagaggca gtccaaatct taggtcagcg tgttggaatt gaggttgaaa
    12061 aaccgcttta tagtgagcag aagccagcct cacctcacca agctctttat gatatgcacg
    12121 aagatgcagc caaattttac catgcgattc tcatgacaac gactatgggc gaagaggcca
    12181 gaaattacct ttatcagcgg ggtttgacag atgaagtgct taaacatttt tggattggtt
    12241 tagcacctcc agaacgaaac tatctctatc aacgtttgtc tgatcagtat cgtgaagagg
    12301 atttactgga ttcaggcctg ttttatctct cggatgccaa tcaatttgta gacacctttc
    12361 acaatcgcat tatgtttccc ctgacaaatg accaaggaaa ggtcattgcc ttctcaggtc
    12421 gtatctggca aaaaacggat tcacaaactt ctaagtataa aaacagccga tcgactgcaa
    12481 tttttaacaa aagttacgaa ttatatcata tggatagggc aaaaaaatct tctggaaaag
    12541 ctagtgagat ttacttgatg gaaggattca tggatgttat tgcagcctat cgggctggaa
    12601 tcgaaagtgc tgtggcgtcg atgggaacgg ccttgagtcg agagcatgtt gagcatctga
    12661 aaaggttaac caagaaattg gttcttgttt acgatggaga taaggctggg caagccgcga
    12721 cattgaaagc attggatgaa attggtgata tgcctgtgca aatcgtcagc atgcctgata
    12781 acttggatcc tgatgagtat ctacaaaaaa atggtccaga agacttggcc tatctattaa
    12841 cgaaaactcg tattagtccg attgagttct acattcatca gtacaaacct gaaaacagtg
    12901 aaaatctgca ggctcagatt gagtttcttg aaaaaatagc tcccttgatt gttcaagaaa
    12961 agtccatcgc tgctcaaaac agctatattc atattttagc tgacagtctg gcgtcctttg
    13021 attataccca gattgagcag attgttaatg agagtcgtca ggtgcaaagg cagaatcgca
    13081 tggaaggaat ttccagaccg acgccaatca ccatgccaat caccaagcag ttatcggcta
    13141 ttatgagggc agaagcccat ctactctatc ggatgatgga atcccctctt gttttgaacg
    13201 attaccgttt gcgagaagac tttgcatttg ctacacctga atttcaggtc ttatatgact
    13261 tgcttggcca gtatggaaat cttcctccag aagttttagc agagcagaca gaggaagttg
    13321 aaagagcttg gtaccaagtt ttagctcagg atttgcctgc tgaaatatcg ccgcaggaac
    13381 ttagtgaagt agagatgact cgaaacaagg ctctcttgaa tcaggacaat atgagaatca
    13441 aaaagaaggt gcaggaagct agccatgtag gagatacaga tacagcccta gaagaattgg
    13501 aacgtttaat ttcccaaaag agaagaatgg agtaataatg gcaacaaaac aaaaagaagt
    13561 aacaacattt gacgtacagg tagcagaatt tatccgtaat cataagcaaa aagggacagc
    13621 aacagatgat gaaatcaatg caagtctggt tattcctttt accttggacg ctgatgggat
    13681 tgaagatctc ttgcaacgga ttcaggatgc aggaatttct atcacagata acgaaggaaa
    13741 tccaagtgcg cgtgttctta gcaatgaaga agaaccagaa ctcagcgatg aggacttgat
    13801 tgggtcaact tctgctaagg tcaatgaccc tgtccgtatg tacttgaaag aaataggggt
    13861 cgttcctctc ttgaccaatg aagaggagaa agagttggca ctggctgttg aagctggtga
    13921 tatcgaagcc aaacaacgtc ttgcggaagc caatcttcgt ttggttgttt ccattgccaa
    13981 acgctatgtc ggtcgtggca tgcagttcct tgacttgatt caagaaggaa atatgggctt
    14041 gatgaaggcg gttgacaagt ttgactattc taaagggttc aagttttcaa cttatgcaac
    14101 ttggtggatt cgtcaggcta tcactcgtgc tattgcggac caagctcgta ccatccgtat
    14161 cccagttcac atggttgaaa ctatcaataa attggttcgt gaacagcgga atctccttca
    14221 agaattgggg caagatccga caccagaaca gattgctgaa cgaatggata tgacacctga
    14281 taaggttcgt gaaatcttga agattgccca agaaccagta tctcttgaaa ctcctatcgg
    14341 tgaagaggac gatagccacc ttggagactt tatcgaagat gaagtgattg aaaatccagt
    14401 ggattatacg actcgtatcg tcttgcgtga gcaattggat gaaatcttag atactcttac
    14461 agaccgtgaa gaaaatgttc tgcgtctacg ttttggacta gatgatggaa aaatgcgcac
    14521 acttgaagat gtggggaaag tctttaacgt aactcgtgag cgtatccgtc agattgaagc
    14581 aaaggctttg agaaaactac gccaaccaag tcgtagcaaa ccgcttcgtg attttattga
    14641 agactaagag tgaggaaaat atggcttata cagaagagca aattgaaaac atcaaaacac
    14701 ggattttaac agccttggaa gaagtcatcg accctgagtt gggaatcgat attgtcaatc
    14761 ttggtttgat ctatgagatt cgttttgacg gtgacacagg gcaaacagag attgacatga
    14821 ctttgacaac tatgggttgt cccttagcag accttttgac agaccagatt tatgatgcta
    14881 tgatagaggt tccagaagta acggatactg aggttaaatt agtctggtat ccagcctgga
    14941 cagttgaaaa aatgagtcgc tatgcccgca ttgccctagg cattaagtaa acatataaaa
    15001 gcatgtgaga gactgttgga aaagcgagga aatttcccct cttttcctct agtctctcct
    15061 ttcttttgct gattttattc aaagaaaatg atataatagt agttatggag aaaaagaaat
    15121 tacgcatcaa tatgttgagt tcaagtgaga aagtagcagg acagggagtt tcaggtgctt
    15181 accgtgaatt agttcgtctt cttcaccgtg ctgccaagga ccaattgatt gttacagaaa
    15241 atcttccaat cgaggcagat gtgactcact ttcatacgat tgattttccc tattatttat
    15301 caaccttcca aaagaaacgc tcagggagaa agattggcta tgtgcatttc ttgccagcta
    15361 cacttgaggg aagtttgaaa attccatttt tcttaaaggg aattgtgaaa cgctatgtat
    15421 tttcttttta caaccggatg gagcacttgg ttgtggtcaa tcctatgttt attgaggatt
    15481 tggtagcagc tggtattcca cgtgaaaaag tgacctatat tcctaacttt gtcaacaagg
    15541 aaaaatggca tcctctacca caagaagagg tagtcagact gcgcacagat cttggtctta
    15601 gtgacaatca gtttatcgta gtaggtgctg ggcaagttca gaaacgtaaa gggattgatg
    15661 actttatccg tctggctgag gaattgcctc agattacctt tatctgggct ggtggcttct
    15721 cttttggtgg tatgacagat ggttatgaac actataagaa aattatggaa aatcccccta
    15781 aaaatttgat ttttccaggc attgtatcgc cagagcggat gcgcgaattg tatgctctag
    15841 cggatctttt cttgttgcct agttacaatg agctctttcc tatgactatt ttagaagctg
    15901 cgagttgtga ggctcctatt atgttgcgtg atttagatct ctataaggta attttggagg
    15961 gaaattatcg ggcgacagcg ggtagagaag agatgaaaga ggctattttg gaatatcaag
    16021 caaatcctgc tgccttaaaa gatctcaaag aaaaggctaa gaatatttcc agagagtatt
    16081 ctgaagagca tctgttacaa atctggttgg acttttatga gaaacaagcc gctttaggga
    16141 gaaagtaaaa agtgaggtaa tctatgcgaa ttggtttatt tacagatacc tattttcctc
    16201 aggtttctgg tgttgcgacc agtattcgaa ccttgaaaac agaacttgaa aagcagggac
    16261 atgctgtttt tatctttacg acgacagata aggatgtcaa tcgctacgaa gattggcaaa
    16321 ttatccgcat tccaagtgtt cctttctttg cttttaagga tcgtcgcttt gcctaccgag
    16381 gttttagcaa ggcacttgaa attgctaaac agtatcagct agatattatc catactcaga
    16441 cagaattttc tcttggcctg ttggggattt ggattgcgcg tgaattgaaa attccagtca
    16501 tccataccta tcacacccag tatgaagact atgtccatta tattgctaag gggatgttga
    16561 tccggccgag tatggtcaag tatctggtta gaggtttcct gcatgatgtg gatggggtta
    16621 tttgtcctag tgagattgtc cgtgacttgc tatctgatta taaggtcaag gttgaaaaac
    16681 gggtcattcc tactgggatt gaattagcca agtttgagcg tccggaaatc aagcaggaaa
    16741 atttgaaaga actgcgtagt aaactaggga ttcaagatgg tgaaaagacg ttgcttagtc
    16801 tttcgagaat ctcctatgaa aaaaatattc aagcagtttt agcagccttt gctgatgttc
    16861 tgaaagagga agacaaggtt aaactggtag tagctgggga tggcccttat ctgaatgacc
    16921 tcaaagagca agctcagaac ctagagattc aagactcagt catctttaca gggatgattg
    16981 ctcctagtga gacggctctt tactataaag cggcggattt cttcatttcg gcatcgacaa
    17041 gcgaaacgca aggtttgacc tacttggaaa gcttagccag tggaacacct gtcattgctc
    17101 acggaaatcc ttatttgaac aacctcatca gtgataaaat gtttggaacc ttgtactatg
    17161 gagaacatga tttggctggt gctattttgg aagccctgat tgcaacacca gacatgaacg
    17221 agcatacctt atcagagaaa ttgtatgaga tttcagctga gaactttggg aaacgagtgc
    17281 atgagtttta tctggatgcc attatttcaa ataacttcca gaaagatttg gctaaagatg
    17341 atacggtcag tcagcgtatc tttaagacag ttttgtatct tcagcaacag gtggttgctg
    17401 tacctgtaaa aggatctaga cgcatgttga aggcttcaaa aacacagttg atcagtatga
    17461 gagactattg gaaagaccat gaagaataga aagaggaaca gctatgaaaa aaacaattaa
    17521 tgagaagcgg tcgtgataaa aagattgcgg gtgtttgtgc tggggtggcc cattatctgg
    17581 atatggatcc gactatcgtt caagtcattt ggggtgttct tacttgctgt tacggagctg
    17641 gaattgtagc ttacattatt ttatggatta tcgcaccagt agcaactgac tattgaaaac
    17701 tagctcaatt catgctaaga taatagaaaa tagaatgtaa cgaaggagag aaaaatggca
    17761 tttggagata atggaaatcg taaaaaaact atgtttgaga aaataacctt gtttatcgtg
    17821 attatcatgc tagtagcaag tttattggga atttttgcaa ctgcaattgg tgccctcagt
    17881 aatctataaa atagattcaa gaaaatttag tgactgggat ttcccagccc ttttttaaag
    17941 tgagaagaaa taatgagtat gtttttagat acagctaaga ttaaggtcaa ggctggtaat
    18001 ggtggcgatg gtatggttgc ctttcgtcgt gaaaaatatg tccctaatgg aggcccttgg
    18061 ggtggtgatg gtggtcgtgg aggcaatgtg gtcttcgttg tagacgaagg actacgtacc
    18121 ttgatggatt tccgctacaa tcgtcatttc aaggctgatt ctggtgaaaa agggatgacc
    18181 aaagggatgc atggtcgtgg tgctgaggac cttagagttc gagtaccaca aggtacgact
    18241 gttcgtgatg cggagactgg caaggtttta acagatttga ttgaacatgg gcaagaattt
    18301 atcgttgccc acggtggtcg tggtggacgt ggaaatattc gtttcgcgac accaaaaaat
    18361 cctgcaccgg aaatctctga aaatggagaa ccaggtcagg aacgtgagtt acaattggaa
    18421 ctaaaaatct tggcagatgt cggtttagta ggattcccat ctgtagggaa gtcaacactt
    18481 ttaagtgtta ttacctcagc taagcctaaa attggtgcct accactttac cactattgta
    18541 ccaaatttag gtatggttcg cacccaatca ggtgaatcct ttgcagtagc cgacttgcca
    18601 ggtttgattg aaggggctag tcaaggtgtt ggtttgggaa ctcagttcct ccgtcacatc
    18661 gagcgtacac gtgttatcct tcacatcatt gatatgtcag ctagcgaagg ccgtgatcca
    18721 tatgaggatt acctagctat caataaagag ctggagtctt acaatcttcg cctcatggag
    18781 cgtccacaga ttattgtagc taataagatg gacatgcctg agagtcagga aaatcttgaa
    18841 gaatttaaga aaaaattgtc tgaaaattat gatgaatttg aagagttacc agctatcttc
    18901 ccaatttctg gattgaccaa gcaaggtctg gcaacacttt tagatgctac agctgaattg
    18961 ttagacaaga caccagaatt tttgctctac gacgagtccg atatggaaga agaagcttac
    19021 tatggatttg acgaagaaga aaaagccttt gaaattagtc gtgatgacga tgcgacatgg
    19081 gtactttctg gtgaaaaact catgaaactc tttaatatga ccaactttga tcgtgatgaa
    19141 tctgtcatga aatttgcccg tcagcttcgt ggtatggggg ttgatgaagc ccttcgtgcg
    19201 cgtggagcta aagatgggga tttggtccgc attggtaaat ttgagtttga atttgtagac
    19261 taggagactg gtatgggaga taaaccgata tctttccgag atgcggatgg taattttgtt
    19321 tccgccgcag acgtttggaa tgaaaagaaa ttggaagaac tatttaatcg tctcaatcca
    19381 aatcgtgcct tgagattggc acgaactaaa aaggaaaatc catctcagta aagaagctaa
    19441 aaaatcccgt gcctcatcag acacgggatt ttgtggtacg acaggcatgt atagcaaact
    19501 gaatctggaa tagcacagca tatcttctaa aatattgcta taaattgatt tgaatttcaa
    19561 aattaaattg ttttattctt atttcaattt gttatagtat atctgatgtc aaagttctcg
    19621 gcgagtcaaa tagtgattcc caagcctgac tatcgtgagg tagcggatta aaatggtctg
    19681 gggatagacc gttttaagtc tgatgctgga aataagaatt gtcagaagaa gggatagcga
    19741 aatcgtggct ctacgaacag gaacgtgata ataaggcgta tatagcgaat aagagggcct
    19801 caaactctaa agtccaaaaa ggtagtcgta acctatatgc gtaaatcatg agagtaattg
    19861 aattcgtact aagattttct atttttactg taacctttta acgtcctcat atcttgtata
    19921 cacgaggaaa gatgtacgac ttatcccgtg aggtctatca ctataaagag aaaacgacag
    19981 atagaagtga tcctgagtca cggttatctt taaaatagat tgtctgatag gatgctagcc
    20041 tgaaaacgtc ttgttcatga aatataggac ggtatgtata aaacgcttct gtgaactgag
    20101 agaaggggga gaagttcttg ctaaaattta gttgaacagc cgtattccga tacttagata
    20161 agagatctag tcttagctcc tactcagttt caggggataa aaaaggggca atagcgattc
    20221 gagaaagatt atactcttcg aaaatctctt caaatcacgt caatatcgcc ttgccgtatg
    20281 tgtaggatac taactacgtc agttccatct acaatctcaa aacagtgttt tgagcaacct
    20341 gcggctagtt tcctagtttg atctttgatt tttattgagt attagtaatt cagttactaa
    20401 ctcgtcaact ctgatttatc caataaaatt gaaaaggatg gaaaaaagga taaatttatg
    20461 atatacttta ttttgaagac cttattagaa atcttgaaag agtattgaaa acttagaatg
    20521 agaaaaattg ttatcaatgg tggattacca ctgcaaggtg aaattactat tagtggtgct
    20581 aaaaatagtg ttgtggcctt aattccagct attatattgg ctgatgatgt ggtgactttg
    20641 gattgtgttc cagatatttc ggatgtagcc agtcttgtcg aaatcatgga attaatggga
    20701 gctactgtta agcgttatga cgatgtcttg gagattgatc caagaggtgt tcaaaatatt
    20761 ccaatgcctt atggtaaaat taacagtctt cgtgcatctt actattttta tgggagcctc
    20821 ttaggccgtt ttggtgaagc gacagttggt ctaccgggag gatgtgatct tggtcctcgt
    20881 ccgattgact tacaccttaa ggcgtttgaa gctatgggtg ccactgctag ctacgaggga
    20941 gataacatga agttatctgc taaagataca ggacttcatg gtgcaagtat ttacatggat
    21001 acggttagtg tgggagcaac gattaatacg atgattgctg cggttaaagc aaatggtcgt
    21061 actattattg aaaatgcagc ccgtgaacct gagattattg atgtagctac tctcttgaat
    21121 aatatgggtg cccatatccg tggggcagga actaatatca tcattattga tggtgttgaa
    21181 agattacatg ggacacgtca tcaggtgatt ccagaccgca ttgaagctgg aacatatata
    21241 tctttagctg ctgcagttgg taaaggaatt cgtataaata atgttcttta cgaacacctg
    21301 gaagggttta ttgctaagtt ggaagaaatg ggagtgagaa tgactgtatc tgaagacagc
    21361 atttttgtcg aggaacagtc taatttgaaa gcaatcaata ttaagacagc tccttaccca
    21421 ggctttgcaa ctgatttgca acaaccgctt acccctcttt tactaagagc gaatggtcgt
    21481 ggtacaattg tcgatacgat ttacgaaaaa cgtgtaaatc atgtttttga actagcaaag
    21541 atggatgcgg atatttcgac aacaaatggt catattttgt acacgggtgg acgtgattta
    21601 cgtggggcca gtgttaaagc gaccgactta agagctgggg ctgcactagt cattgctggg
    21661 cttatggctg aaggtaaaac tgaaattacc aatatcgagt ttatcttacg tggttattct
    21721 gatattatcg aaaaattacg taatttagga gcggatatta gacttgttga ggattaaacc
    21781 gtagaggtgt ttatgaatat ttggaccaaa ttagcaatgt tttctttttt tgaaacggat
    21841 cgcttgtatt tgcgtccttt cttttttagt gatagtcagg acttccgcga gatagcttca
    21901 aatccagaaa atcttcaatt tattttccca acgcaggcaa gtctggaaga aagtcaatat
    21961 gcactggcca attactttat gaagtcccct ttgggagtgt gggcaatttg tgaccagaaa
    22021 aatcaacaaa tgattggttc tattaaattt gagaagttag atgaaatcaa aaaagaagct
    22081 gagcttggct attttttgag aaaagatgct tggtcgcaag gatttatgac agaggttgtt
    22141 agaaaaattt gtcagctttc ttttgaggaa tttggcttaa aacaattatt tatcattacc
    22201 caccttgaaa atgaagctag ccaaagagtt gctcttaagt ctggatttag tttgttccgt
    22261 cagtttaagg gaagtgatcg ttacacaaga aaaatgcggg attatcttga atttcggtat
    22321 gtaaaaggag agttcaatga gtaagcatca ggaaattcta agctatttgg aggaattacc
    22381 agtaggtaaa agggtcagtg ttcgtagcat ttcgaatcat ctaggagtta gtgatggaac
    22441 agcctatcga gctattaaag aagctgaaaa ccgtggaatt gtggagaccc gtcctagaag
    22501 tggaacaatt cgtgttaaat cccagaaagt tgctatagag agattaacgt ttgctgaaat
    22561 tgcagaagtg acttcttctg aggttctggc tgggcaagaa ggtttagaga gagagtttag
    22621 taagttttca attggtgcca tgactgaaca aaatatcttg tcttaccttc atgatggggg
    22681 gctcttgatt gtcggagacc gaacccgtat tcagttgcta gccttggaaa atgaaaatgc
    22741 agttctggtt acagggggat ttcaggttca tgatgatgtg cttaaactgg ccaatcaaaa
    22801 agggattcct gttctaagaa gtaagcatga tacctttacc gtcgcgacca tgatcaataa
    22861 agccttgtca aatgtccaaa tcaagactga tattctgaca gttgagaaac tttatcgccc
    22921 tagtcatgag tatggttttc tgagagagac agatacagtt aaagattatt tggacttggt
    22981 tcgtaagaat cgtagcagcc gtttccctgt tatcaatcaa catcaggtcg ttgttggtgt
    23041 tgtaaccatg agagacgctg gtgataaatc accaagcacg acaattgata aggttatgtc
    23101 tcgtagtcta ttttgggttg gattatcgac aaatattgcc aatgtgagtc aacggatgat
    23161 cgcagaagac tttgaaatgg taccagttgt tcgaagcaat caaactttgc ttggcgttgt
    23221 gacgcgacga gatgtcatgg agaagatgag ccgttcccaa gtttcggctc taccaacttt
    23281 ttctgagcag attggacaaa agctctctta tcaccatgat gaagtagtca ttacagtgga
    23341 accctttatg ctagaaaaaa atggagtttt ggctaatggt gtattggcag aaattctgac
    23401 ccacatgacc caagatttag ttgttaatag tggtcgcaat ctcattatcg agcagatgct
    23461 gatctacttt ttgcaggctg ttcagataga tgatatattg cgcattcagg cacggattat
    23521 tcatcatacg agacggtcag ctataattga ttacgatatt tatcatggtc accagattgt
    23581 ttcaaaagca aatgtgactg ttaaaattaa ttagaaacta ggagaaaaga tgataacatt
    23641 aaaatcagct cgtgaaatcg aagctatgga caaggctggt gattttctag caagtattca
    23701 tataggctta cgtgatttga ttaagccagg cgtagatatg tgggaagttg aagaatatgt
    23761 ccgccgtcgt tgtaaagaag aaaatttcct tccacttcag attggggttg acggtgccat
    23821 gatggactat ccttatgcta cctgttgctc tcttaacgat gaagtggctc acgctttccc
    23881 tcgtcattat atcttgaaag atggtgattt gctcaaagtt gatatggttt tgggaggtcc
    23941 cattgctaaa tccgacctga atgtctcaaa attaaacttc aacaatgttg aacaaatgaa
    24001 aaaatacact cagagctatt ctggtggttt agcagactca tgttgggctt atgctgttgg
    24061 tacaccgtcc gaagaagtca aaaacttgat ggatgtaacc aaagaagcta tgtacaaggg
    24121 tattgagcaa gctgttgttg gaaatcgtat cggtgatatc ggtgcggcta ttcaagaata
    24181 cgctgaaagt cgtggttacg gtgtagtgcg tgatttggtt ggtcatggtg ttggcccaac
    24241 tatgcacgaa gaaccaatgg ttcctaacta tggtattgca ggtcgtggac tccgtcttcg
    24301 tgaaggaatg gtcttaacca ttgaaccaat gatcaataca ggcgattggg aaattgatac
    24361 agatatgaaa actggttggg cgcataagac cattgacggt ggattgtcat gtcagtatga
    24421 acaccaattt gtcattacga aagatggacc tgttatcttg actagccaag gtgaagaagg
    24481 aacttattaa taaaaagtga aaagactact ggaagtttat tttgataaaa aatccagtag
    24541 atcttttcat aataaaacgc attgtatcaa gtgttaggag ctgatatcat gcgtttttct
    24601 gcttttaaga ttttttccaa ctctgtttgt aagcgcatca taacaaaggg tctaggattc
    24661 agggctctcc tcctatatac tattagtaaa gtaaaactaa gagaggatat tttagtgtcg
    24721 cagtctattg ttcctgtaga gattccacaa tattgtcgtt ttgattctaa aaagagaaat
    24781 ggaattctgt ttaacgttcg tattgccaat cttaaattta ccttttttag attagacttc
    24841 ctgcgaaata aaatatggta tagtagttct atgaatgatg aagcaagtaa acaactaact
    24901 gatgcacgat ttaagcgtct tgttggtgtt cagcgcacga cttttgaaga gatgttagct
    24961 gtattaaaaa cagcttatca acttaaacac gcaaaaggtg gacgaaaacc taaattaagc
    25021 ctagaagacc ttcttatggc cactcttcaa tatgtgcgag aatatcgaac ttatgaagaa
    25081 attgcggc
//
LOCUS       DAVHTH010000030        24906 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.030, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000030 DAVHTH010000000
VERSION     DAVHTH010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24906)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24906)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24906
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.030"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     misc_binding    complement(204..433)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(645..1646)
                     /locus_tag="VVR63_001259"
     CDS             complement(645..1646)
                     /locus_tag="VVR63_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000789954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU6129278.1"
                     /translation="MKNINGKKVTIYDIARLSGFSPKTVSRVINGGVNVKEETYQAIQ
                     KVIEELSYIPNAYAKNLTKKEAINILISVKKIDSFPLIWFHTLLDKVLRTCKEFGVNA
                     IVEYFGEEDTISNSIISSTGSLVDGVIVFYESVDDIRIQYLKKNHMPFLVFGESQTSG
                     VVYVSNNNFQATYDMMKAVTEEKFKNMWLLMGGESHVNKDRERGVRSFLNDKNYFMDL
                     KVIYGLSTIDSVYSYAMQHLTTQNYPDIIFVSGDEKVQGLIRACYEKGILIPDDISII
                     GFDNIPISQYYTPALSTIAPNYVKLAKEMIEGVLAIIKGESVTSVEVSPKFVRRQSF"
     gene            complement(1754..2122)
                     /locus_tag="VVR63_001260"
     CDS             complement(1754..2122)
                     /locus_tag="VVR63_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6129279.1"
                     /translation="MKDYKINFDLGKIEYFDNNCLIQVYKFISFYDICEMVFAFHLPP
                     DELITNVIFKEKINSMLKCYIDRLLYVFINPTHFTEKVNLQFYGSFFSYEFICREVGN
                     ILKNKGVKCNLNFFEGEEYL"
     gene            complement(2218..2928)
                     /locus_tag="VVR63_001261"
     CDS             complement(2218..2928)
                     /locus_tag="VVR63_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HEU6129280.1"
                     /translation="MTATSLGLSNIEIVVRIVLSVVIGSIIGLERGSKSQPAGIRTYS
                     IVCLAACLIMMTNEYVSYKFGTGDPTRLGAQVISGVGFLGAGTILITDKKKITGLTTA
                     AGIWASAGIGLAIGVGFYEGALLVAISVWGVISMFQPLKKYLQNRSKMIELYIVVKST
                     EAYNRVLVYCAENGIRMTDSRTAFGDVNSDRIEYFDVPDKKIASFITLELSGRFEHLR
                     LMEEIANIVGVIYVEEIS"
     gene            complement(2931..4622)
                     /locus_tag="VVR63_001262"
     CDS             complement(2931..4622)
                     /locus_tag="VVR63_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEU6129281.1"
                     /translation="MRHKLNLKDWLIRLGLIWFLVTFIIYPNFDLVVNVFVKGGEFSL
                     DAVHRVLKSQRALQSIMNSFKLAFSLIITVNVVGILCVLFTEYFDIKGAKILKLGYMT
                     SLIYGGVVLATGYKFVYGPYGLITKFLQNVIPSLDPNWFIGYGAVLFIMTFSGTANHT
                     LFLTNTIRSVDYHTIEAARNMGAKPFTVFRKVVLPTLIPTLFALTIMVFLSGLSAVAA
                     PMIVGGKEFQTINPMIITFAGMGNSRDLAALLAIILGIATTILLTIMNKIEKGGNYIS
                     ISKTKAPLKKQKIASKPWNIIAHIVAYGLFTVFMLPLIFIVLYSFTDPVAIQTGNLTL
                     SNFTLENYRLFFSNSAAFSPFLVSFIYSIIAATTATILAVVFARVVRKHKSRFDFLFE
                     YGALLPWLLPSTLLAVSLLFTFNQPQFLVLNQILVGSLVILLIAYIVVKIPFSYRMVR
                     AILFSVDDEMEDAARSMGASPFYTMMKVIIPFILPVVLSVIALNFNSLLTDFDLSVFL
                     YHPLAQPLGITIRSAGDETATSNAQALVFVYTIVLMIISGTVLYFTQRPGRKVRK"
     gene            complement(4634..5644)
                     /locus_tag="VVR63_001263"
     CDS             complement(4634..5644)
                     /locus_tag="VVR63_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6129282.1"
                     /translation="MIKFDNIQIKYGDFVAIDNLNLDIHEGEFFTFLGPSGCGKSTTL
                     RALVGFLDPSSGSIEVNGTDVTHLEPEKRGIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VAPDVIKAKVSAVAAKIKISDQQLQRNVSELSGGQQQRVALARALVLEPKILCLDEPL
                     SNLDAKLRVDLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGYIEQVGTPV
                     EIYHNSQTEFVCDFIGDINVLTDETVHEVLLKNTSVFLEDKKGYIRLEKVRFNRETEQ
                     DFILKGTIIDVEFSGVTIHYTIKVSESQILNVTSIDSQAAIRSVGESVELFITPSDVL
                     QF"
     gene            complement(5748..6815)
                     /locus_tag="VVR63_001264"
     CDS             complement(5748..6815)
                     /locus_tag="VVR63_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEU6129283.1"
                     /translation="MKKMKVWSTVLATGVALTTLAACSGGSNSTTASSSEEKADKSQE
                     LVIYSNSVSNGRGDWLTAKAKEAGFNIKMVDIAGAQLADRVIAEKNNAVADMVFGIGA
                     VDSNKIRDQKLLVQYKPKWLDKIDQSLSDKDNYYNPVIVQPLVLIGAPDVKEMPKDWT
                     ELGSKYKGKYSIYGLQGGTGRAILASILVRYLDEKGDLGVSEKGWEVAKEYFANAYTL
                     QKGESSVVKALDKESPIQYGMIWGSGALIGQKEQNVEFKVMTPEIGVPFVTEQTMVLS
                     TSKKQALAKEFIDWFGQSEIQVEYSKKFGSIPANKDALKELPEDTKKFVDQVKPQNID
                     WEAVGKHLDEWVEKAELEYVK"
     gene            complement(6840..7499)
                     /locus_tag="VVR63_001265"
     CDS             complement(6840..7499)
                     /locus_tag="VVR63_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000793810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1868 domain-containing protein"
                     /protein_id="HEU6129284.1"
                     /translation="MKNLTKIKFKENGEFNHFPGNTVVANLYTKQDLMEVVDIIQSRY
                     RELPFIDKFTLTPRNSIHMTVIELLCHENRETEFWSSNLPLDTPLQEIHDYFAKQLEI
                     FPLLDEEIHMRITEMGKQNILVEPADEASAKRLEEIRTYVSEKAGVCFPNHDRYQFHI
                     SIGYLRIPLTEEEEEEFTKVRAELTEILLEKIPTITVNRIDYTVFEDMRQFVPYHEKF
                     K"
     gene            complement(7709..8689)
                     /gene="galE"
                     /locus_tag="VVR63_001266"
     CDS             complement(7709..8689)
                     /gene="galE"
                     /locus_tag="VVR63_001266"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEU6129285.1"
                     /translation="MAILVTGGAGYIGSHTVVELLNLGKEVIIVDNLSNSSILVLDRI
                     EAITGIRPVFYELDVCDKPALRKVFEQESIDAAIHFAGYKAVGESVQKPVMYYKNNIM
                     STLALVEVMSEFNVKKIVFSSSATVYGINNQSPLIETMQTSATNPYGYTKVMLEQILK
                     DVHVADSEWSIALLRYFNPIGAHESGLIGEDPSGLPNNLMPYIAQVAVGKLSELSVFG
                     NDYDTLDGTGVRDYIHVVDLAIGHIKALEKVSEKTDVYIYNLGSGEGTSVLQLVNTFE
                     SVNKIPIPYKIVPRRSGDVATCYANADKAYKELNWRTTKSIEDMCRDTWN"
     gene            complement(8702..10177)
                     /gene="galT"
                     /locus_tag="VVR63_001267"
     CDS             complement(8702..10177)
                     /gene="galT"
                     /locus_tag="VVR63_001267"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HEU6129286.1"
                     /translation="MKTIIDNFVDRVIEYGMYNEIDKIYVKNRVLALIGEEGTDRISD
                     ENDLKQIKDYLVEIALKNGKIKDLIEEKECLGAELMNFIVPLPSRLNDIFWSSYDISP
                     QEAVEEFYKLSKDSDYIKTSAIAKNIEFRASTKYGELEITINLSKPEKDPKTIAAEKL
                     VKATNYPKCLLCMENEGYQGRINYPARSNHRIIRLKLGDEVWGFQYSPYLYFNEHAIF
                     LNSQHVPMAITSKTFEQLLEIVDILPGYFAGSNSDLPISGGSILSHNHYQGGKHIFPM
                     EKAKFESEFRFKDFEDVNAGIVKWPMSVIRLQSENKNRLLDLATKILNKWREYSDLEV
                     DIIAMTEDVPHHTVTPIARKVDGRYELDIVLRDNHTTEQYPDGVFHPHQDVQHIKKEN
                     IGLIEVMGLAILPPRLKPELEEVGKYLLGEDNAIADYHLEWADQLKEKYPRINKEEVN
                     SVVQHEAGQVFARVLEDAGVYKNTPSGHEAFMRFVKSVGIN"
     gene            complement(10190..10831)
                     /locus_tag="VVR63_001268"
     CDS             complement(10190..10831)
                     /locus_tag="VVR63_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate uptake regulator PhoU"
                     /protein_id="HEU6129287.1"
                     /translation="MLRLYLENEIIELSNNLETIWVSVLDKYEKLFEYLSNEERIELI
                     KEDLIINESVLNVDKKGYELICLQHPVSYDLRRIISVIKISTDIERIGDRIVEILKNL
                     QIIQNNEILKKIISEIKILHEVIGLHMNRAISCYREEQSGCLDMVVIQKQNEIEELST
                     NIEKKIMNYIFEDDGNVSEVIGALDIIHHLDKIAHTTQSIYKWIMYRKYGNIN"
     gene            complement(10889..11101)
                     /locus_tag="VVR63_001269"
     CDS             complement(10889..11101)
                     /locus_tag="VVR63_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6129288.1"
                     /translation="MDERFLDHAIINQIDVTSEQIVLMSDGFYEFYQNNQNKTFEELI
                     KMRFNSSAIDPIYGKKDDASIVVIDV"
     gene            complement(11444..11740)
                     /locus_tag="VVR63_001270"
     CDS             complement(11444..11740)
                     /locus_tag="VVR63_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6129289.1"
                     /translation="MVKINKICSIQGSSVENEDIVGSQNQYFWIIGGATDLYNSKEEI
                     GYSVSEVVHILSESLSVNCKESKTLKQIFETALLEVKDEIGLNSYELTEYNKMK"
     gene            complement(11724..13883)
                     /gene="pfbA"
                     /locus_tag="VVR63_001271"
     CDS             complement(11724..13883)
                     /gene="pfbA"
                     /locus_tag="VVR63_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multi-ligand-binding adhesin PfbA"
                     /protein_id="HEU6129290.1"
                     /translation="MLKIVKKLEVLMKYFVPNEVFSIRKLKVGTCSVLLAISILGSQG
                     ILSDEVVTSSSPMATKESSNAITNDLDNSPTVNQNRSAEMIASNSTTNGLDNSLSVNS
                     ISSNGTIRSNSQLDNRTVESTVTSTNENKSYKEDVISDRIIKKEFEDTALSVKDYGAV
                     GDGIHDDRQAIQDAIDAAAQGLGGGNVYFPEGTYLVKEIVFLKSHTHLELNEKATILN
                     GINIKNHPSIVFMTGLFTDDGAQVEWGPTEDISYSGGTIDMNGALNEEGTKAKNLPLI
                     NSSGAFAIGNSNNVTIKNVTFKDSYQGHAIQIAGSKNVLVDNSRFLGQALPKTMKDGQ
                     IISKESIQIEPLTRKGFPYALNDDGKKSENVTIQNSYFGKSDKSGELVTAIGTHYQTL
                     STQNPSNIKILNNHFDNMMYAGVRFTGFTDVLIKGNRFDKKVKGESVHYRESGAALVN
                     AYSYKNTKDLLDLNKQVVIAENIFNIADPKTKAIRVAKDSAEYLGKVSDITVTKNVIN
                     NNSKETEQPNIELLRVSDNLVVSENSIFGGKEGIVIEDSKGKITVLNNQFYNLSGKYI
                     SFIKSNANGKEPVIRDSDGNFNIVTENGLYKIVTNNLSDKNEKEKNKEEKQSNSNNVI
                     DSNQKNGEFNSSKDNRQMNDKIDNKQDNKTEEVNYKIVGDGRETENHINKSKEIVDVK
                     QKLPKTGSNKIMELFLTVTGIGLLLTLKGLKYYGKDK"
     gene            complement(15014..16240)
                     /locus_tag="VVR63_001272"
     CDS             complement(15014..16240)
                     /locus_tag="VVR63_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS aminotransferase family
                     protein"
                     /protein_id="HEU6129291.1"
                     /translation="MPNYNIPFSPPDITEAEIAEVADTLRSGWITTGPKTKELERRLS
                     LYTQTPKTVCLNSATAALELILRVLEVGPGDEVIVPAMTYTASCSVITHVGATPVMVD
                     IQADTFEMDYDLLEQAITEKTKVIIPVELAGIVCDYDRLFQVVEKKRDFFTASSKWQK
                     AFNRIVIVSDSAHALGSTYKGQPSGSIADFTSFSFHAVKNFTTAEGGSATWKANPVID
                     DEEMYKEFQILSLHGQTKDALAKMQLGSWEYDIVTPAYKCNMTDIMASLGLVQLDRYP
                     SLLQRRKDIVDRYDSGFAGSRIHPLAHKTETVESSRHLYITRVEGASLEERNLIIQEL
                     AKAGIASNVHYKPLPLLTAYKNLGFDMTNYPKAYAFFENEITLPLHTKLSDEEVDYII
                     ETFKTVSEKVLTLSKK"
     gene            complement(16283..16975)
                     /locus_tag="VVR63_001273"
     CDS             complement(16283..16975)
                     /locus_tag="VVR63_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000922225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEU6129292.1"
                     /translation="MLKWEDLPVEMKSSEVESYYQLVSKRKGSLIFKRCLDWVLALVL
                     LVLTSPIFLILSIWIKLDSKGPVIYKQERVTQYNRRFKIWKFRTMVTDADKKGSLVTS
                     ANDSRITKVGNFIRRVRLDELPQLVNVLKGEMSFVGTRPEVPRYTEQYSPEMMATLLL
                     QAGITSPASINYKDEDTIISQMTEKGLSVDQAYVEHVLPEKMRYNLAYLREFSFFGDI
                     KIMFQTVFEVLK"
     gene            complement(17148..18899)
                     /locus_tag="VVR63_001274"
     CDS             complement(17148..18899)
                     /locus_tag="VVR63_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6129293.1"
                     /translation="MQNKQEQWTVLKRLMSYLKPYGLLTFLALSFLLATTVIKSVIPL
                     VASHFIDQYLSNLNQLAVTVLLVYYGLYILQTVVQYVGNLLFARVSYSIVRDIRRDAF
                     ANMEKLGMSYFDKTPAGSIVSRLTNDTETISDMFSGILSSFISAVFIFLTTLYTMLVL
                     DFRLTALVLLFLPLIFLLVNLYRKKSVKIIEKTRSLLSDINSKLAENIEGIRIIQAFN
                     QEKRLQAEFDEINQEHLAYANRSVALDALFLRPAMSLLKLLGYAVLMTYFGYRGLSIG
                     ITAGTMYAFIQYINRLFDPLIEVTQNFSTLQTSMVSAGRVFALIDERTYEPLQENGQA
                     KVKEGNIRFEHVCFSYDGKHPILDDISFSVNKGETIAFVGHTGSGKSSIINVLMRFYE
                     FQSGRVLLDDVDIRDFSQEELRKNIGLVLQEPFLYHGTIKSNIAMYQEISDEQVQAAA
                     AFVDADSFIQELPQGYDSPVSERGSSFSTGQRQLLAFARTVASQPKILILDEATANID
                     SETESLVQASLAKMRQGRTTIAIAHRLSTIQDANCIYVLDKGRIIESGTHEELLTLGG
                     TYHKMYSLQAGAMAYTL"
     gene            complement(18889..20634)
                     /locus_tag="VVR63_001275"
     CDS             complement(18889..20634)
                     /locus_tag="VVR63_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6129294.1"
                     /translation="MSIIQKLWWFFKLEKRRYLVGIVALVLVSVLNLIPPMVMGRVID
                     AITSGQLTQQDLLLSLFYLLLAAFGMYYLRYVWRMYILGTSYCLGQIMRSRLFKHFTK
                     MSSAFYQTYRTGDLMAHATNDINALTRLAGGGVMSAVDASITALVTLLTMLFSISWQM
                     TLVAILPLPFMAYATSRLGRKTHKAFGESQAAFSELNNKVQESVSGIKVTKSFGYQAD
                     ELKSFQAVNELTFQKNLQTMKYDSLFDPMVLLFVGSSYVLTLLVGSLVVQEGQITVGN
                     LVTFISYLDMLVWPLMAIGFLFNTTQRGKVSYQRIENLLSQESPVQDPEFPLDGIENG
                     RLEYAIDSFAFENEETLTDIHFSLAKGQTLGLVGQTGSGKTSLIKLLLREYDVDKGAI
                     YLNGHDIRDYRLTDLRSLMGYVPQDQFLFATSILDNIRFGNPNLPLSAVEEATKLARV
                     YQDIVDMPQGFDTLIGEKGVSLSGGQKQRLAMSRAMILDPDILILDDSLSAVDAKTEY
                     AIIDNLKETRKDKTTIITAHRLSAVVHADLILVLQNGQIIERGRHEDLLALDGWYAQT
                     YQSQQLEMKGEEDAE"
     gene            complement(20762..21292)
                     /locus_tag="VVR63_001276"
     CDS             complement(20762..21292)
                     /locus_tag="VVR63_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000174443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HEU6129295.1"
                     /translation="MTLNYIEILIKLVLTLKWLNNNVHFVKRLIDGKPTLLIKNGNID
                     PEACRSVGLSASDVALKLRSQGIFQMKQVKRAVQEQNGQLIVVQMGDENPKYPVVTDG
                     VIQVDVLESIGRSEEWLLDNLSKQGHDNVANIFIAEYDKGAVTVVTYEKEKPGVLYSS
                     KISSNRVNVALPYVGY"
     gene            complement(21289..21745)
                     /locus_tag="VVR63_001277"
                     /pseudo
     CDS             complement(21289..21745)
                     /locus_tag="VVR63_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730499.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3290 family protein"
     gene            21879..22706
                     /gene="xth"
                     /locus_tag="VVR63_001278"
     CDS             21879..22706
                     /gene="xth"
                     /locus_tag="VVR63_001278"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HEU6129296.1"
                     /translation="MKLISWNIDSLNAALTSDSARAKLSQEVLQTLVAENADIIAIQE
                     TKLSAKGPTKKHVEILEELFPGYENTWRSSQEPARKGYAGTMFLYKKELTPTISFPEI
                     GAPSTMDLEGRIITLEFDAFFVTQVYTPNAGDGLKRLEERQVWDVKYAEYLAELDKEK
                     PVLATGDYNVAHNEIDLANPASNRRSPGFTDEERAGFTNLLATGFTDTFRHVHGDVPE
                     RYTWWAQRSKTSKINNTGWRIDYWLTSNRIADKVTKSDMIDSGARQDHTPIVLEIDL"
     gene            22718..22816
                     /locus_tag="VVR63_001279"
     CDS             22718..22816
                     /locus_tag="VVR63_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HEU6129297.1"
                     /translation="MDYNAVIPEFLVSNIEQSRSFYCGLLGFRIEY"
     gene            22861..23100
                     /locus_tag="VVR63_001280"
     CDS             22861..23100
                     /locus_tag="VVR63_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HEU6129298.1"
                     /translation="MLEEGTKDQLAELTYPFGRGVNLSFGIKDVPKLYQKVMEANYPI
                     YRLLTKRKFRVSDPYIYPHKFAVLDPDGYFLRFSE"
     regulatory      23483..23578
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            23978..24559
                     /locus_tag="VVR63_001281"
     CDS             23978..24559
                     /locus_tag="VVR63_001281"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HEU6129299.1"
                     /translation="MKLLEERILKDGHILGDNILKVDSFLTHQVDFSLMREIGKVFAE
                     KFAATGITKVVTIEASGIAPAVFTAEALNVPMIFAKKAKNITMNEGILTAQVYSFTKQ
                     VTSTVSIAGKFLSPEDKVLIIDDFLANGQAAKGLIQIIEQAGATVQAIGIVIEKSFQD
                     GRDLLEKAGYPVLSLARLDRFENGQVVFKEADL"
     gene            24559..>24906
                     /locus_tag="VVR63_001282"
     CDS             24559..>24906
                     /locus_tag="VVR63_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001194492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HEU6129300.1"
                     /translation="MQTQEKHSQAAVLGLQHLLAMYSGSILVPIMIATALGYSAEQLT
                     YLISTDIFMCGVATFLQLQLNKYFGIGLPVVLGVAFQSVAPLIMIGQSHGSGAMFGAL
                     IASGIYVVLVSGIF"
BASE COUNT         7812 a         5051 c         4032 g         8011 t
ORIGIN      
        1 cctgcggcta gtttcctagt ttactctttg attttcattg agtattacta gcttttttcg
       61 tattagtcca gctttttgtt tgcttttagt agtaggcaag gagctgtaga tagaactcaa
      121 gttcatcaaa gcgacttaag gccctaataa aagataaacc aaacgacgga tagaaaaaag
      181 cccacacaca aaatatactt ccgtgtgagg gcgttggtaa cgcggtgcca cctcaattat
      241 aaagggacta tccctttaca tctctgcctt gtttaacaac aagctgcact gtaaggtgtg
      301 cgcaccgaat tttcattgtt tcaaattcat tttcaaaatc agcccacttt cactacttcc
      361 aaccacctat tcacaaccac cacaggctcc ctgaagatca aaaatagtta cttttctgat
      421 ttgttgaact tattttaata ctttgttttt tctttgtcaa gactttttta cgattttttt
      481 gaaaatatca ttcgaatgtg accatgtctt ccttagatcg aacatgaaca tgtcccactt
      541 gttagaaatt ggatccaact caatagaaac tgaatggagg ctaaacagaa cttattttag
      601 aacactccat cttttccact aggattttca agaattaaac aatactagaa actctgtctc
      661 ctaacaaatt taggagaaac ttcaacagat gtgacacttt cccctttaat aattgctaaa
      721 acaccttcta tcatttcttt agccaattta acataattgg gagcaattgt agacaaagct
      781 ggagtataat actgagaaat aggaatatta tcaaatccaa tgatagaaat atcatctgga
      841 ataagaattc ctttctcata gcacgcacga atcaagccct gaaccttttc atctcctgaa
      901 acaaaaataa tgtccggata attttgggta gtcaagtgct gcattgcata agaataaact
      961 gaatcaattg tagataagcc ataaatgact tttaaatcca taaagtaatt tttatcattc
     1021 agaaaagaac gcacacctct ttcacgatcc ttattaacat gggattctcc tcccataagc
     1081 aaccacatat ttttaaattt ttcttcagtt acagctttca tcatatcata agtagcttga
     1141 aaattattat tagatacata gactactcca gacgtttgag attcaccgaa aacaagaaaa
     1201 ggcatatggt tcttctttaa atactgaatt ctgatatcat ctacactttc ataaaaaaca
     1261 ataacaccat ctactaggct acctgtgctt gatataattg aattactaat tgtatcctcc
     1321 tctccaaagt actcaactat agcattaaca ccaaattctt tacacgtccg taacacttta
     1381 tctaacagcg tatgaaacca aattaaagga aaagagtcga ttttttttac agaaatcaat
     1441 atatttatag cttctttttt agttaaattt tttgcatacg catttggaat atacgacaat
     1501 tcctctataa ctttttgaat cgcttgataa gtttcttctt taacatttac tccaccatta
     1561 ataactcgtg aaactgtttt tggagaaaaa cctgataaac gtgcaatatc ataaatagtt
     1621 acctttttcc catttatatt tttcatttca gtcctccatt acgaacattc taatattact
     1681 atacaatatt taattttttt taacaagaga atttagtaaa ttatttaaga tccacaaatt
     1741 cacaaaatta attttacaaa tattcttccc cttcaaaaaa gtttaaattg catttcacac
     1801 ctttattttt aagaatgttt ccaacttcac gacaaataaa ttcatatgag aaaaaactac
     1861 cataaaattg tagattaact ttttcagtaa aatgtgtagg atttataaaa acatataata
     1921 gcctgtcaat gtaacatttt aacatagagt taattttttc tttaaagata acatttgtta
     1981 tcaactcatc aggaggtaaa tgaaaggcaa acaccatttc acaaatatca taaaaagaaa
     2041 taaatttgta tacttgtatc aaacaattat tatcaaaata ttctatttta cctaaatcaa
     2101 aattgatttt ataatctttc ataaaaacct ctgagcaaaa atctactcaa aaattagatg
     2161 attaaaacat ctaaaaaaca aaaggacaaa aacatctgtc cctttgttta ctaaatttca
     2221 gctaatttct tcgacataaa taacacctac aatattagca atttcttcca tcagtcgaag
     2281 atgttcaaat ctacctgata attccagagt aataaatgac gctatttttt tgtccggaac
     2341 atcaaagtat tcaattctgt cagaattaac atctccaaac gctgttcttg aatcggtcat
     2401 tctgatacca ttttctgcac aataaaccaa tacacgatta taggcttctg tagatttaac
     2461 cactatatac aattcaatca ttttagaacg attttgcaga tattttttta gtggttggaa
     2521 catggatatc acaccccaaa cagaaatggc tactaaaaga gctccctcat aaaaacctac
     2581 tccaatagct aatccaattc ctgccgaagc ccaaatgcct gctgcagttg tcagacctgt
     2641 aattttcttt ttatctgtaa taagaatcgt tccagcgcct agaaaaccca cacctgatat
     2701 aacttgagct cctaatcgtg taggatctcc tgtcccaaat ttataagata cgtattcatt
     2761 cgtcatcata atcaaacatg cagctagaca aacaatacta taagttcgga tgcctgcagg
     2821 ctgggatttg ctccctctct ctaaaccaat tatactacca atgactactg ataaaacaat
     2881 cctgacaact atttcaatat ttgataaccc aagactagtg gctgtcatga ttatttcctt
     2941 actttacgcc ccggtctttg tgtgaagtat aataccgttc cagaaatgat catcagaaca
     3001 attgtataaa caaataccag agcttgtgca ttagatgttg ctgtttcatc acctgcagat
     3061 cgaatcgtaa tacctaatgg ttgagctagg ggatggtaaa ggaatacaga taagtcgaag
     3121 tcagttaata aagagttaaa gtttaaagca ataacagaga gaacaaccgg taaaataaat
     3181 ggaatgataa ccttcatcat agtataaaaa ggtgaagcac ccatacttct tgctgcatct
     3241 tccatctcat catcaacact aaataaaata gcacgtacca ttctataaga aaatgggatt
     3301 tttacaacta tatatgcaat aagtagaatt accaaactac ctaccaaaat ctgattcaag
     3361 acaagaaatt gtggctgatt aaaagtaaat aataaactta ctgctaaaag tgtacttggt
     3421 agtaaccaag gaagtagagc accatattca aataagaaat caaaacgaga tttatgtttt
     3481 ctgacaacac gagcaaatac aactgcgaga attgttgctg ttgtcgcagc aataatagaa
     3541 taaataaagc tgaccaagaa tggagagaat gccgcactat tactaaagaa taagcgataa
     3601 ttttctaaag taaagtttga taatgttaag ttacctgttt gaattgcaac tggatctgta
     3661 aatgagtata atactataaa aattagtgga agcatgaaaa ctgtgaacaa tccatatgct
     3721 acaatgtgag caatgatatt ccaaggctta gacgcaattt tttgtttttt aagaggcgct
     3781 ttagtcttag agatagaaat ataatttcca cctttttcta tcttattcat gatagtaagc
     3841 aaaattgtag ttgcaatacc taaaataatt gcaagtaagg cagctaaatc acgagaattc
     3901 cccatccctg caaatgtaat aatcattgga tttatagttt gaaattcttt accaccaaca
     3961 atcatgggtg ctgctactgc agataaacca ctaagaaaaa ccataatagt aagtgcaaat
     4021 agagttggaa ttaaggttgg taacactact tttcggaaaa cagtaaatgg ttttgctccc
     4081 atatttcgag cagcctcaat agtgtgatag tcaacgcttc gaattgtatt tgttaaaaac
     4141 aatgtatgat tagcagttcc tgaaaatgtc ataatgaata agactgcacc atacccaata
     4201 aaccagttag ggtctaaaga agggataaca ttttgtaaaa attttgtaat caatccatat
     4261 ggaccataga caaatttata tccagtcgct aaaaccactc ctccataaat taaagaggtc
     4321 atataaccta attttaaaat tttagcacct ttaatatcaa agtactctgt aaatagaacg
     4381 caaagaatac ctacgacatt aactgtaata atgagtgaaa atgctaactt aaaactgttc
     4441 ataatactct gaagtgccct ctgagatttt agaacacgat gtacagcatc aagggaaaat
     4501 tctcctcctt ttacaaatac attcactact agatcaaagt ttggataaat aataaatgtt
     4561 actaagaacc agattaaccc taaacgaata agccaatctt ttaaatttaa tttatgacgc
     4621 atactgcacc tccttaaaat tgcagaacgt ctgatggtgt gataaataat tccacacttt
     4681 ctccgacaga tctaatagca gcctgactat caatacttgt tacattaaga atctgacttt
     4741 cagaaacttt tattgtatag tgaattgtaa ctccagaaaa ctcaacatca ataattgtcc
     4801 cttttagaat aaaatcttgt tcagtttcac gattgaatcg aactttctct aatcgaatgt
     4861 atcctttttt atcctctaag aaaacgcttg tatttttcaa taatacttcg tggactgttt
     4921 catcggtcaa aacattaata tctccaataa aatcacatac aaattcagtt tgagaattat
     4981 gataaatctc tactggtgta ccgacctgtt cgatgtatcc attgttaaag actgcaattc
     5041 tatcagataa agtcaaggct tcctcttgat catgagtaac atataaagta gtaataccta
     5101 actctttttg aagtcttttc aactcttttc tcaaatctac acgtaatttt gcgtcaaggt
     5161 ttgacaatgg ttcatctaga caaagaattt taggttcaag aaccagagca cgagccaatg
     5221 ctaccctttg ttgttgaccc ccagataatt ctgatacatt acgctgtaac tgttgatcag
     5281 agatcttaat ttttgctgcc actgctgata ctttagcttt aataacatct ggagctacct
     5341 tcttaacttt taaaccaaat gcaatattat caaaaacagt catagttgga aatagcgcat
     5401 aagattgaaa tacaatacca attccacgct tttcaggttc caaatgagtg acatctgttc
     5461 cattaacttc aatacttcct gatgatggat ctaaaaaacc taccaatgct ctcaaagtag
     5521 ttgatttacc acatcctgaa ggcccaagaa atgtaaagaa ttccccttca tgtatatcta
     5581 aattcagatt atcaattgca acaaaatcac catatttaat ttgaatatta tcaaatttaa
     5641 tcatctcact aactccctct attactaaaa ccaaaagcct ctctttattt cttccttaaa
     5701 tttagaaata atagagagac ttggacataa aaaataactc ttatttctta ttttacgtat
     5761 tctaattcag ctttttctac ccattcatcc aaatgctttc caacagcttc ccagtcaata
     5821 ttttgtggtt tcacttgatc aacaaatttt ttcgtatctt caggtaactc ttttagggca
     5881 tctttatttg caggaataga tccaaatttt ttactatatt ctacttgaat ttctgattga
     5941 ccaaaccaat caataaattc tttagctaac gcttgttttt tactagtgct taaaaccata
     6001 gtttgttcag ttacaaatgg tacaccaatc tcaggagtca taactttgaa ttcaacattt
     6061 tgttcttttt gtccaattaa cgctccagaa ccccagatca taccgtattg aattgggctt
     6121 tctttatcta acgctttaac aactgagctt tcaccttttt gaagagtata ggcatttgca
     6181 aagtattctt ttgcaacttc ccatcctttt tctgatacgc ctaaatctcc tttttcatca
     6241 aggtaacgaa ctaagatact tgctagaatt gcccgtcctg taccaccttg aagaccataa
     6301 attgaatatt tacctttata cttactacct aattcagtcc aatctttagg catttctttt
     6361 acatcaggcg ccccaattaa aactaatggt tgaacaatca caggattata ataattatct
     6421 ttatctgata aagattgatc aattttatct aaccatttag gcttgtactg tactagtaat
     6481 ttttgatctc taattttatt tgagtcaaca gcaccaattc caaataccat atctgcaact
     6541 gcattattct tctcagcaat aacacggtct gctaattgag cgccagcgat atcaaccatt
     6601 tttatattaa aaccagcttc ttttgcttta gcagttaacc aatcaccacg accatttgag
     6661 actgagttcg aatagataac taattcttga cttttatcag ctttttcttc agatgaagaa
     6721 gcagtcgtag aatttgaacc tccagagcaa gcagcaagtg tagtaagagc aactcccgtt
     6781 gcaagtacag tagaccaaac tttcattttt ttcatgataa gttctccttt tttattattt
     6841 tatttaaatt tttcgtgata tggaacaaat tgtctcatat cttcaaatac agtatagtca
     6901 atacggttta cagtaatagt tggaatcttc tctaataaaa tttcagttaa ttctgctctg
     6961 actttagtaa actcttcttc ctcctcttcg gttagaggaa tccgaagata cccaattgaa
     7021 atatggaatt gatatctatc atgattaggg aaacaaacac ctgctttttc tgagacataa
     7081 gtacgaattt cttctaatct ctttgcagaa gcttcatctg caggttcaac tagtatgttt
     7141 tgttttccca tttcagttat acgcatatga atttcttcat ccaacaatgg aaaaatttca
     7201 agttgtttag caaagtaatc atgtatttcc tgtaaaggtg tatctagagg aagattactg
     7261 ctccaaaact ccgtttcacg attttcatgg cacaacaatt caattacagt catgtgaata
     7321 gaattccttg gagttaaagt aaacttatcg ataaatggta attctctata acgtgattga
     7381 ataatatcaa caacttccat caaatcttgt ttagtataaa gatttgctac aactgtattc
     7441 ccagggaaat gattaaattc cccattctct ttgaacttaa tttttgttaa gtttttcata
     7501 taaagacctt cttttttata tttgacatcg gtgtcactat gtttacatta tacaatgaaa
     7561 ccgtttcctt tgtcaagcgc tgtcaaacat tttttttaat ttatctttca ttaaatatgc
     7621 atttcattaa aaggttaagt aatttttcca aaatacagca ctcatataga cagtatcatc
     7681 aattatagcc attgggattt tttgattgct aattccatgt atctctacac atgtcttcaa
     7741 tcgattttgt tgtcctccaa tttaattcct tatatgcttt gtctgcattt gcataacaag
     7801 ttgcaacgtc tcctgaacgt cttggaacta ttttataagg aatagggatc ttattaacac
     7861 tttcaaatgt atttacaagt tgtaatacac tagtgccttc tcccgagcct aggttataga
     7921 tataaacatc tgttttttca gatacttttt ctaaagcttt tatatgtcct attgctaaat
     7981 ctactacatg gatataatca cgcacaccag taccatcaag cgtatcataa tcatttccga
     8041 acacacttag ctctgatagc ttacctaccg ctacttgtgc aatataaggc atcaagttgt
     8101 taggaagtcc tgagggatct tccccaatca aaccagactc atgagcacca attggattga
     8161 aataacgaag caacgcaata ctccattctg aatctgccac atgaacatct tttaaaattt
     8221 gctcaagcat cactttcgta tacccataag gatttgtcgc acttgtttgc atcgtctcaa
     8281 ttagaggtga ctgattgtta attccatata cagtcgcact tgaagaaaag acaatctttt
     8341 taacattaaa ttctgacatc acttcaacaa gtgccaatgt actcataata ttatttttgt
     8401 agtacatcac aggcttttgc acggattctc cgacagcttt ataacctgca aaatgaattg
     8461 cagcatcaat cgattcttgt tcaaatacct ttctcaatgc tggtttatca caaacatcta
     8521 attcgtaaaa cacgggacgt attcctgtaa ttgcttcaat acggtctagc accaagatgc
     8581 tagagttcga aaggttgtcg acaatgatga cttcctttcc taaatttagt aattctacta
     8641 cggtatggct accaatataa ccagctccgc ctgttaccaa tattgccatt tttgtttcct
     8701 cctaattaat tccaaccgac ttaacaaatc tcataaacgc ttcatgccca gacggtgtat
     8761 tcttataaac tcctgcatct tccagaactc tcgcaaacac ttgtcctgct tcgtgttgaa
     8821 ctacgctatt aacctcttct ttattaatgc gaggatattt ttctttcaat tggtcggccc
     8881 attctaaatg ataatccgca attgcgttat cctctcctaa aagatatttt ccaacttctt
     8941 ctaactctgg tttcaaacga ggtggtaata tcgcaagtcc catcacttcg attaacccga
     9001 tattttcctt tttaatatgt tgtacatctt gatgaggatg gaaaacacca tctgggtact
     9061 gttcagtagt atgattatct cttagaacaa tatctaattc atatctcccg tccactttac
     9121 gagcaatagg agtcaccgta tggtgtggga catcttcagt catagcaatg atgtctactt
     9181 ctaaatctga atattctctc cacttattta gaattttagt agctaaatct aacaagcgat
     9241 ttttattttc actttgtaac ctaattactg acattggcca ttttacaata ccagcattaa
     9301 catcctcaaa gtctttaaaa cgaaattcac tctcaaattt tgctttttcc attgggaaaa
     9361 tatgtttccc tccctggtag tggttatgac taagaatgga gcctcctgag ataggaagat
     9421 cagaatttga accagcaaaa tatcctggca aaatatcaac aatctccaat aattgttcaa
     9481 atgttttaga ggtaatagcc attggtacat gttgactatt taaaaatatc gcatgctcat
     9541 taaagtataa gtagggagaa tattggaatc cccatacttc gtcaccaagt ttcaatcgaa
     9601 taattctatg attcgaacgt gctggataat ttattcgccc ctgatatcct tcattttcca
     9661 tacatagtaa acatttggga taattagtgg cttttactaa tttttcagca gcaattgttt
     9721 ttggatcttt ttcgggtttt gacaaattta tcgtaatctc tagctctccg tatttagttg
     9781 atgctcgaaa ctcaatattc ttagcaatag cagaagtttt aatataatca ctatctttac
     9841 ttaacttata aaactcttca actgcttctt gaggtgatat atcatatgaa ctccaaaaaa
     9901 tatcatttaa tcgactaggt aaaggaacta tgaaattcat taactctgct cctaaacatt
     9961 ccttttcctc gattaaatct ttaattttac cgttttttaa ggcgatttcc actaagtaat
    10021 cttttatttg tttcaggtca ttttcatcgg aaatgcgatc agttccctcc tcacctatta
    10081 acgctagtac tctatttttc acatatattt tgtcaatttc attatacatt ccgtattcaa
    10141 ttactctatc aacaaaatta tcaataattg ttttcatata tttttctttc taatttatgt
    10201 tcccatattt tctatacatt atccatttat aaattgattg cgtagtatga gcaattttat
    10261 caaggtgatg aataatatct aaagcaccaa ttacttcaga aacattccca tcatcttcaa
    10321 atatgtaatt cattattttc ttttcaatat ttgtactaag ctcttctatc tcattctgtt
    10381 tttgtataac aaccatatct aaacatccag attgttcctc tctataacaa gatatagccc
    10441 tattcatatg cagtccgata acttcatgaa gtatttttat ttctgaaata attttcttca
    10501 aaatttcatt attttgaata atctgtagat tttttaaaat ttcaacaatt ctatccccaa
    10561 tacgttcaat gtcagttgat atttttatta cactaataat tcttcttaag tcatatgaaa
    10621 cgggatgttg taaacaaatt aactcatatc cttttttatc aacatttaga actgactcat
    10681 ttatgattaa atcttcttta atcaattcta ttcgttcttc atttgataaa tattcaaata
    10741 acttctcata tttatcaagc acagataccc aaatggtctc taaattattt gataattcta
    10801 taatttcatt ttctaaatat aaccttaaca tttaggtacc tcttcttaac aaagttcaat
    10861 agtaacaatt aatattttaa acaatatatc aaacatcaat aactacaata cttgcatcat
    10921 ctttctttcc atagattgga tcaatagcag aagaattaaa tctcatctta attaactctt
    10981 caaaagtttt attttgatta ttttgataga attcataaaa gccatcgctc attaaaacaa
    11041 tttgttcact agtaacatct atttgattaa taatagcatg gtctaaaaat ctctcatcca
    11101 acgaacctat ccagtaccca ctcggttgat tagataattt tctgattttt tgtaaaataa
    11161 tttttttatt taaaacacta tttgtaccaa ttggatcttt tatctcattt ttcccttttt
    11221 caaataagtt atctactcta tgatccgtta tttccatttc gtttactaac atgacgcagt
    11281 cacctagcat catatactcc aacttttttt ctgaaagttt agcaaatata aaagcaaatg
    11341 ttggtaagcg ataatatagt atattgaaac tagaatagta cacctctact tctaaaacat
    11401 tgttagaaat cgatttgact gtcctgattg atttgtccta ttattatttc attttattat
    11461 actctgttaa ttcatatgag tttaaaccga tttcatcttt aacctcgagt aaagcagttt
    11521 caaatatttg tttaagagtt tttgattctt tacaattaac cgacaaactt tctgataaaa
    11581 tatgtacaac ttctgagact gaataaccta tctcctcttt agaattatat aaatctgtag
    11641 ctccaccaat aatccaaaaa tactgatttt gtgaacctac aatatcctca ttttctacgg
    11701 aacttccttg tatcgaacaa attttattta tctttaccat aatacttcaa cccttttagt
    11761 gtcaaaagta aaccaattcc tgtcactgtt aagaatagtt ccataatctt gttcgaacca
    11821 gtctttggta atttttgttt tacatctact atttctttag atttattaat atgattttca
    11881 gtttctctgc catctccaac tattttatag tttacttctt ctgtcttatt atcttgttta
    11941 ttgtcgatct tgtcattcat ttgtctatta tctttacttg agttaaactc tccgttcttc
    12001 tggttactat caattacatt atttgaatta gattgttttt cctctttgtt tttttctttt
    12061 tcgtttttat cacttaaatt atttgttaca attttgtaaa gcccattctc cgttacaata
    12121 ttgaaattac catcgctatc acgtataaca ggttctttcc cgtttgcatt agatttgatg
    12181 aatgatatat acttaccgga taaattataa aattggttat ttaaaacggt tattttaccc
    12241 tttgaatcct caataacaat tccttcttta ccaccgaata tactattctc tgacactact
    12301 aaattatcac taactcgtaa taattcaata tttggttgtt ctgtttcctt agaattatta
    12361 ttaattacat tttttgttac agtaatatct gatacttttc ctaaatattc tgcactatct
    12421 tttgcaactc gtatcgcttt tgttttagga tcggcaatat taaatatatt ttcggcgata
    12481 accacctgtt tatttaaatc taataggtct ttagtgtttt tatagctata agcatttact
    12541 aaagctgctc cgctttctcg ataatgtaca ctctctcctt taactttctt atcaaagcga
    12601 tttcctttga ttaatacatc agtgaatcct gtaaaacgta cacctgcata catcatgtta
    12661 tcaaaatgat tatttaaaat tttaatatta gaggggttct gtgtcgacaa tgtttgatag
    12721 tgtgtgccaa ttgctgttac taattcccca gatttatcac ttttgccaaa ataggaattt
    12781 tgaatagtca cattttcaga ttttttccca tcatcattca aggcataagg aaaacctttt
    12841 ctagttaatg gttcaatctg aatgctctcc ttacttatga tttgcccatc cttcatcgtt
    12901 ttgggtaagg cttgcccaag aaaacgagaa ttatcaacta atacattttt cgaacctgca
    12961 atttgaatag catgcccttg ataactatcc ttgaatgtta cattttttat agttacgtta
    13021 tttgaattcc caatagcaaa tgcacctgaa gaatttataa gtggtagatt ttttgcttta
    13081 gttccttctt cattcaaagc accgttcata tcaatcgtac caccagaata actaatatct
    13141 tctgttgggc cccattctac ttgcgcacca tcatccgtaa ataaacctgt cataaaaaca
    13201 atggaagggt gattcttaat atttatacca tttagaattg tagctttctc attcaattct
    13261 aagtgtgtat gactttttaa aaaaacaatt tcttttacta aataagttcc ttcaggaaaa
    13321 tatacatttc ctccacctag cccttgagct gcagcatcta ttgcatcttg aattgcttgt
    13381 cgatcatcat gaatcccatc acctaccgca ccataatctt ttacacttaa agcagtatct
    13441 tcaaattctt ttttgataat tctgtcactt ataacatctt ccttataact cttattttca
    13501 ttagtagatg ttactgtaga ttcaactgtt ctgttgtcta attgtgaatt ggaacgaata
    13561 gtaccattag agctgatact attaacactt aacgaattat ctaaaccatt agtggttgaa
    13621 ttagaggcaa tcatttcagc agaacgattc tgattaacag ttggtgaatt atctaaatca
    13681 ttagtaattg cattagaaga ctcttttgta gccatcggtg aagaactagt aacaacttca
    13741 tccgataaaa taccttggct tcccaaaatt gaaattgcca atagtaccga gcaagtcccc
    13801 acctttaatt tacgaatact gaatacctca ttaggaacaa aatatttcat cagaacctcc
    13861 aattttttta ctatttttaa caattgatta ttacttttct taaaatagat agaatgacac
    13921 cgctgtcatt atctttatca tatattttcc aaattgaatt gtcaaggaat aacacaagaa
    13981 aatattaaaa tttatactct tcggaaatct cttcaaacta ggtcagtgcc gccttgccct
    14041 aagtctaggt tactgacttg gtcagttcta tagtagactg aaactataat agtacacctc
    14101 tacttctaaa acattgttag aaatcgattt aactgtcccg atcaatttgt cctattcttg
    14161 tttcatttta ctatatctac aacctcaaag cagggttttg agctatctat ggccaacttc
    14221 ctagtttgct ctttagcctt ccattcaaaa gtgatgctat ctttcttagc ttgaatataa
    14281 aatatcccat ttactatatt taaatttgtt gatatgttgt aaattataaa tgaaagaaca
    14341 aataccttgt catacaagca ttcgccaggg atatttacct gaatatcgct catatggcgg
    14401 attgaaacta aaacactaca atatatttct taaatagacc ttctataaaa gctagattta
    14461 acctcgataa aaatagatgc agtgcttcta aaatactgga atagggcata taggtaatcg
    14521 tagacaagtg ttttatagat tgtctcgcag gagatctaat gatgtatagc aagcatcact
    14581 aaacatatgg gatatttgcg ttattataat atcaacatgc tataaattct atcatgcaaa
    14641 agaatgacta gaacatgaaa gacaggcaca aaactttgaa caatattctg aaaacaaaaa
    14701 aaagacgcta gtttccacaa tctcactcat ggaaactcac gtctttcaaa aaatagggtg
    14761 aattgaaaac tagaacaaga cactagattt tctaaatgat gtctagtaag gattctaaat
    14821 gctataccaa attgctcaca tcttatttca aaccacggga ctcccacaag aaaggaaaat
    14881 cctataaaaa ttctctctct gaggagaaag aggcctcaac tacaggtgta aactattatc
    14941 aattgaaaac aacagttttt acactcaatt agacttttta gggacaggat cactttcgct
    15001 tgactgtagt ttgtcatttt tttgataaag ttagcacttt ttcagaaact gttttgaaag
    15061 tctcaatgat atagtctact tcttcatcgc ttaatttagt atgaagaggg agggtaattt
    15121 cattctcaaa gaaggcatag gccttaggat agttcgtcat atcaaatcca agattcttat
    15181 aggctgtcaa gagaggaagc ggtttgtagt gaacattact tgcaattcct gctttagcca
    15241 attcttggat gatgaggttg cgttcttcta ggcttgctcc ttctacacgg gtgatgtaga
    15301 ggtggcgtga agattcgaca gtttcagtct tgtgtgccaa aggatggatg cgagaacctg
    15361 caaaaccact atcatagcgg tccacaatgt ccttacggcg ttgcaacaaa cttggatagc
    15421 ggtccaattg taccaaacca agtgaagcca tgatatcggt catgttgcac ttataggctg
    15481 gtgtaacgat atcgtattcc catgacccca gttgcatctt ggcaagagca tccttagttt
    15541 gcccgtgaag ggaaaggatt tggaattcct tgtacatctc ttcgtcatca atcactggat
    15601 tggctttcca agtcgcactt ccaccttctg ccgttgtaaa gttcttaaca gcatggaatg
    15661 agaaggaagt aaaatcagcg atagaaccag aaggttgtcc tttataagta gatcccaaag
    15721 cgtgggcact atcagagaca atgacaatac ggttaaaggc cttttgccac ttgcttgaag
    15781 cggtaaagaa gtcacgtttt ttctccacga cttggaacaa acggtcataa tcgcaaacaa
    15841 tccctgcgag ctctactggg ataatcacct tagttttctc agtgatagct tgctcaagca
    15901 ggtcatagtc catctcaaac gtatctgctt ggatatccac catgacaggg gttgctccca
    15961 cgtgcgtaat gacactacat gaagccgtat aggtcatggc tggaacgatg acttcatcac
    16021 caggtcccac ttccaaaacg cgtaaaatca actccagagc ggctgtcgca gagttgagac
    16081 aaacagtctt aggtgtctgt gtgtaaagag acaagcggcg ctccagttct tttgttttag
    16141 gacctgttgt gatccaacca gaacgcaggg tatccgctac ttcagcaatt tctgcttctg
    16201 tgatatcagg cggtgaaaat ggaatattgt aatttggcat tgatttgctc cttttatctg
    16261 tactcatttt cttatgacta ctttatttta gtacctcaaa cacggtttga aacatgattt
    16321 tgatgtcccc aaagaaacta aactctcgga gataggcgag gttatagcgc atcttttcag
    16381 gaagaacatg ctccacatag gcctgatcaa ctgacagacc tttctccgtc atttgactga
    16441 tgatggtgtc ctcatccttg tagttgatgc tggctggaga ggtaattcct gcttgcaaga
    16501 gcaaggttgc catcatttca gggctatact gctctgtata acgtggcact tcaggtcgtg
    16561 taccgacaaa ggacatctca cctttaagga cattgaccaa ctgaggcagt tcgtccaaac
    16621 ggacacgtcg gatgaaattt ccaaccttgg taatacggct atcgttagca gaagtcacca
    16681 gacttccttt tttatccgca tccgtcacca tggtacggaa cttccaaatc ttgaaccgac
    16741 ggttgtactg ggtcacacgc tcttgcttgt aaatcactgg ccccttgcta tccaacttga
    16801 tccaaatgct caagatgaga aagatgggag aagttagaac cagtaagacc aaggccaaaa
    16861 cccagtccaa gcaacgcttg aaaatcagcg aacccttcct tttagagaca agctggtagt
    16921 aagactcaac ctcgcttgat ttcatttcca caggcaagtc ttcccatttc agcatgctgt
    16981 tctcctttgt ttttattata ctatttgtca acatttttca ttataccaca aaatggaaaa
    17041 ggcggtgaaa gaaatctgta atttgaagga tttccttcta gtactcaatg aaaatcaaag
    17101 tacagctttg agattgcaga taaagctgac atggtttaaa gagattttca aagagtatag
    17161 gccatggccc ctgcctgcaa actatacatc ttgtgatagg ttcctcccag agtcaagagt
    17221 tcctcatggg ttccactctc gataatgcgt cccttatcca agacatagat gcagttggcg
    17281 tcttgaatag tagaaaggcg gtgagcgata gcaatagttg ttcggccctg tctcatcttc
    17341 gccagagaag cttgaaccaa actttctgtt tcagagtcaa tattggctgt cgcttcatcc
    17401 aaaatcagga ttttaggctg gctggcgact gttctagcaa aggcaagaag ctggcgctgc
    17461 ccagtagaga agctcgaacc acgctcggaa acaggggagt cgtacccctg aggaagttct
    17521 tgaataaagg aatctgcatc cacaaaggct gccgcagcct gaacctgctc atcactgatt
    17581 tcttggtaca tggcgatatt ggacttaata gttccatgat agaggaaggg ttcctgtaaa
    17641 accaaaccga tgttttttct cagctcttct tgactgaaat ccctgatatc cacatcatcc
    17701 aagagaactc tccctgactg gaattcataa aagcgcatga ggacattgat aatagacgat
    17761 ttccctgaac ctgtatgacc tacaaaggca atggtttcac ccttattaac agagaaagaa
    17821 atgtcatcca gaatcggatg tttaccgtca tacgagaaac acacatgttc aaaacggata
    17881 ttgccttctt tgactttggc ttgcccattt tcttgaaggg gctcataggt cctctcatcg
    17941 attaaggcaa agacacggcc tgcagaaacc atagacgttt gcagtgttga aaagttttgc
    18001 gtcacctcaa tcaaagggtc aaagaggcgg ttgatgtact ggataaaagc atacatggtc
    18061 ccggccgtta tcccgataga aagaccacga tagccaaaat aggtcatcaa gacagcataa
    18121 cctagaagtt tcaacaaact catggcaggt ctcaaaaaga gggcatccaa ggctacagaa
    18181 cggttggcat aggccaagtg ctcttggttg atttcatcaa attctgcctg caggcgcttc
    18241 tcttgattaa aagcctgaat aatcctgatt ccctcgatat tctctgccag cttactattg
    18301 atatctgaca agagacttct ggttttctcg atgattttca ctgacttttt tcgatagaga
    18361 ttgaccaaaa ggaaaatcaa ggggagaaag agcaagacta aagccgtcaa acgaaaatcc
    18421 agcaccaaca tggtataaag ggttgtcaga aagataaaaa ctgctgagat aaagctggat
    18481 aaaatcccag aaaacatatc actaatcgtc tcggtatcgt tggtcaaacg agaaacgata
    18541 gaacctgctg gcgtcttgtc aaagtaagac atgcccagtt tctccatatt ggcaaaggca
    18601 tcccgacgaa tatccctaac aatactgtaa gacacgcgcg caaagagaag attgccgaca
    18661 tactgaacta cagtttgtag gatgtagaga ccatagtaga ccagcaaaac ggtcacggct
    18721 agttggttaa gattgctgag atactggtcg ataaagtggg aagccacaag gggaatgaca
    18781 cttttaatga ccgtcgtcgc taggagaaaa ctgagtgcca aaaaggtaag gagtccataa
    18841 ggcttgagat aggacatcaa gcgcttcaat acagtccatt gttcttgttt attctgcatc
    18901 ttcttctccc ttcatttcca gctgctgaga ctggtaggtt tgggcatacc agccatccaa
    18961 agctagcaag tcttcgtgcc tgcctcgttc gataatttga ccattttgca ggactaaaat
    19021 caaatctgca tggacaactg cactcaggcg atgggcagtg ataatggttg tcttgtcctt
    19081 tcgcgtctcc ttgaggttgt cgataatcgc atactctgtc ttggcatcta cggcggataa
    19141 ggaatcatcc aaaatcaaga tatcagggtc taaaatcata gcccgactca tagccaaccg
    19201 ttgcttttga ccaccagaaa gactgactcc tttttcacca atcagcgtat caaatccttg
    19261 aggcatgtct acaatatctt ggtaaactcg ggctagctta gtagcttcct cgaccgctga
    19321 aaggggcaag ttaggattgc caaagcggat attgtctagg attgaagtcg caaaaagaaa
    19381 ctggtcctga ggaacatagc ccatgagact gcgaaggtct gtcagacgat agtcccgaat
    19441 atcgtgaccg tttagataaa tggcgccctt atccacatcg tattcacgca agaggagctt
    19501 gattaaggac gttttcccag agcctgtctg cccaaccaag cccagtgttt gcccttttgc
    19561 caaactaaag tgaatatccg tcagtgtttc ctcattttca aaagcaaagc tgtcaatggc
    19621 atactccaaa cgcccatttt caataccatc cagaggaaac tccgggtctt gtacaggaga
    19681 ttcctgagac aaaagatttt caatccgctg gtaagaaacc ttccctcgct gagtagtatt
    19741 aaagaggaag ccgatggcca taagaggcca gaccagcata tccaaatagc tgataaaggt
    19801 gactagattc ccaactgtaa tctgcccttc ctgaaccacc aaggagccaa ccaaaagcgt
    19861 taaaacatag gacgaaccaa caaacaagag aaccataggg tcaaagagac tatcatattt
    19921 catggtttgc aggttctttt ggaaggttaa ttcattgact gcctgaaaag acttcaactc
    19981 gtctgcctga taaccgaaag acttggtcac tttgatacct gatacggact cctgtacctt
    20041 gttattgagt tcagaaaaag cagcttggga ttcgccaaag gccttatgag tctttctccc
    20101 taggcgacta gtcgcatagg ccatgaaagg tagggggaga atggcaacaa gagtcatctg
    20161 ccatgagatg ctaaagagca tggtcaacaa agtcaccaga gccgtgatag aggcatccac
    20221 cgcagacatg acaccgccac ctgctaaacg agtcaaggca ttgatatcat tggttgcgtg
    20281 tgccatcaga tcacccgtcc gataggtttg ataaaaggct gacgacattt ttgtgaaatg
    20341 cttaaacaag cgagaccgca tgatctgtcc caagcaataa gaggtcccaa ggatatacat
    20401 acgccacaca tagcgcaaat agtacatacc aaaggctgca agtagcaagt aaaataggct
    20461 aagaaggagg tcctgctggg ttaattgccc cgatgtgatg gcatcaataa cccgccccat
    20521 aaccatagga ggaatgagat tgaggacgga aaccaagacc agggccacaa ttccgactag
    20581 ataacggcgt ttttctaact tgaaaaacca ccaaagtttt tgaataatgg acataaaatc
    20641 cctttctgat tgcaaatgga aacctgaggc caatactcaa tgaaaatcaa agagcaaact
    20701 aggaaactag ccgcaggctg ctcaaagcac tgctttgagg ttgtagatag aactgacgaa
    20761 gtcagtaacc tacatacggc aaggcgacgt tgacgcggtt tgaagagatt ttcgaagagt
    20821 acaagacccc aggtttttct ttttcataag ttacgactgt aacagcaccc ttgtcatatt
    20881 cagcaataaa gatattggct acattgtcat gcccttgttt actgaggtta tcaagcaacc
    20941 actcttcgct acgaccaatc gattccaaga catctacttg aatcacaccg tcagtcacaa
    21001 ctggatactt aggattttca tctcccattt gcacaacgat aagttgccca ttttgctctt
    21061 gcacagctcg tttgacttgc ttcatctgga aaatcccttg gctacgaagt ttgagggcta
    21121 catccgatgc agacaaacca actgaacgac aggcttctgg gtcaatattc ccatttttga
    21181 taaggagagt tggcttacca tcaatcaaac gtttcacaaa gtgaacattg ttgttgagcc
    21241 atttgagagt caagaccagt ttgattaaaa tttcgatata attaagtgtc atttgttcac
    21301 atccaccagt tcaattgcgt ctgtcttata caattcgact ttctctaaca ggtacttgtc
    21361 tggctcactt ccgtttaggg cacgataata gcgatctccc accttgataa gtgcgccatc
    21421 tgtgtttgtg gaagtattaa catagacttc tgacttgtct actcccaaat ctttggaaac
    21481 aacctcgatg aaatgaagtg aagtttgaaa tttattgtta gaaacttgat tgttttgata
    21541 agtcgtgatg ctgaccaaaa gcagagctaa ataaggccag agctgaaatc atgaccaact
    21601 cacgaaattc ggttcccttt ttatcatggt atgccttgaa agcaaaaaaa actgtcacag
    21661 ctaatagaac aatcccaaag ccaaccatga taccattttg ctgaccgatt tggctgagta
    21721 catagtcata agagtagaat ttcatatatt ttcactccct ttcataaaat cattcttaat
    21781 tataaacgaa agagagtaat ttttcaaacc atacgttggg gaaatagatc tttttttggt
    21841 ataataaaat ctataatctg aatgaaaaag gtaactttat gaaacttatc tcatggaata
    21901 ttgattccct aaacgctgcc ctaactagtg actcagctcg tgccaaattg tcccaagaag
    21961 tcctacaaac cttggtcgct gaaaatgctg atatcattgc tatccaagaa accaagcttt
    22021 ctgccaaagg acctacaaag aaacacgtgg aaattttaga agaactcttc ccaggctacg
    22081 aaaacacatg gcgctcttcc caagagcctg cccgtaaagg ctatgctgga accatgttcc
    22141 tttataagaa agaacttacg cctacgatca gttttccaga aatcggtgcc ccttctacca
    22201 tggacttgga aggccgtatc atcactctag aatttgatgc atttttcgta acccaagttt
    22261 acactccaaa cgctggtgac ggtctcaaac gcttggaaga acgccaagtc tgggatgtta
    22321 aatatgctga gtatttggct gaactagaca aagaaaaacc agtccttgcg accggtgact
    22381 acaacgtagc ccacaatgaa atcgaccttg caaatcctgc tagcaaccgc cgttcacctg
    22441 gatttactga cgaggaacgt gctggattta ccaacctttt ggcaactgga tttacagaca
    22501 ccttccgcca tgttcatggc gatgttcctg aacgctacac ttggtgggca caacgcagca
    22561 aaacttctaa aatcaacaat acaggctgga gaatcgacta ctggctcaca agtaaccgta
    22621 tcgctgacaa ggtcactaaa tctgatatga ttgactcagg tgctcgccaa gaccatacac
    22681 cgattgtctt ggaaattgac ttgtaaggat tttctatatg gactacaatg cggtcattcc
    22741 cgagtttctt gtatcgaata tcgaacagtc ccggtccttc tactgtggtt tactgggttt
    22801 taggattgaa tactaacgtc cagaagaaaa ctttctcttt ctcttgaaga gtgtcaacta
    22861 atgttagagg agggaacaaa ggatcaacta gctgaactga cctacccctt tggtcgtgga
    22921 gtcaatctct cctttggcat aaaggatgtt ccaaaactct atcaaaaagt gatggaggca
    22981 aactatccta tttatcgtct cttgaccaaa agaaagtttc gtgtcagtga tccctatatc
    23041 tatcctcata aatttgcagt tttggatcca gatggctatt ttttaagatt tagcgagtag
    23101 aataataaaa attgggaaaa gtctttaaag ttagaaaaag gcatattgtc aggtgtctaa
    23161 aaacttgata gtatgccttt tatgatggaa aaatcttcta atactcttcg aaaatctctt
    23221 caagccacgt caacgtcgcc ttaccgtagg tatatgatac tgactctgtc aattctatcc
    23281 acaacctcaa aacagtgttt tgaggttgtg gatagcttcc tagtttgctc tttgattttc
    23341 atttagtata aatgttagct tacaatggag tttttgttca ccctctctta tttttgttcg
    23401 ctttttaaac caaaacacta acaaaatagt tgatttctaa agttatttag tgtaaaataa
    23461 aaacattggc tcaagcctat ttaaaattga atatcgtttt acttgtttat gtcgtgaatt
    23521 ggcacgacgt ttctacaagg tgccggaaca cctaacaata agtaagtcag cagtgagata
    23581 tggccgtttt tgccatgtct atttagggga cttacttaga gattaagtag gtcttttttg
    23641 aatattttta atatttccct taattagtgc ggacgggagg tgaaattatc ctgtgaataa
    23701 tttcaggaat ccagggaatt tcatccctaa tttttgagcc cctagctctt tcatttctag
    23761 gcttaggcta aaatagttcc ccgaactatt ttactctcaa aaatcccgtc atagacaata
    23821 acaagattat tgtctatgat accactacaa cgggaaatat ttgataagac tcgcttcgct
    23881 cgtaatagtt ttatcaaata tatagtatta gcaaaaggga tcactataga aacatttaaa
    23941 caacaagtaa attaactttt agactttagg aggtcttatg aaattattag aagagcgcat
    24001 cctcaaggat gggcatatct tgggtgataa catcctcaag gtagattcct ttttaaccca
    24061 ccaagttgac tttagcttga tgcgagagat tggtaaggtt tttgcggaaa aatttgctgc
    24121 tactggcatt accaaggtcg taaccattga agcgtcgggt attgccccag ccgtttttac
    24181 agctgaagcc ttaaacgttc ccatgatttt cgccaaaaaa gctaagaaca tcaccatgaa
    24241 cgaaggcatc ttaactgctc aagtctactc ctttaccaag caggtgacca gcactgtttc
    24301 tatcgctgga aaattcctct caccagagga caaggttttg attatcgacg atttccttgc
    24361 taatggccaa gctgctaaag gcttgattca aatcatcgaa caggccggtg ccacagtcca
    24421 agctatcggt atcgtgattg agaaatcctt ccaagatggt cgtgatttgc ttgaaaaagc
    24481 aggctaccct gtcctatcac ttgctcgctt ggatcgtttt gaaaatggtc aggtcgtatt
    24541 taaggaggca gatctctaat gcaaactcaa gaaaaacact cgcaagcagc cgttctgggc
    24601 ttgcagcact tactagccat gtactcagga tctatcctgg ttcccatcat gattgcgaca
    24661 gcccttggct attcagctga gcagttgacc tacctgattt ctacagatat cttcatgtgt
    24721 ggggtggcaa ccttcctcca actccaactc aacaaatact ttgggattgg actcccagtc
    24781 gttcttggag ttgcattcca gtcggtcgct cccttgatta tgattgggca aagccatggt
    24841 agtggcgcta tgtttggtgc ccttatcgca tctgggattt acgtggttct tgtttcaggc
    24901 attttc
//
LOCUS       DAVHTH010000031        23908 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.031, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000031 DAVHTH010000000
VERSION     DAVHTH010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23908)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23908)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23908
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.031"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            complement(222..302)
                     /locus_tag="VVR63_001283"
                     /pseudo
     CDS             complement(222..302)
                     /locus_tag="VVR63_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(357..581)
                     /locus_tag="VVR63_001284"
     CDS             complement(357..581)
                     /locus_tag="VVR63_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory secretory protein Asp5"
                     /protein_id="HEU6129301.1"
                     /translation="MIEILIVLAIILSLALIVLVTIQPRQNQLFSMDATSNIGKPSYW
                     QSNTLVKVLTLLVSLALFVLLLTFMVITYK"
     gene            complement(586..765)
                     /gene="asp4"
                     /locus_tag="VVR63_001285"
     CDS             complement(586..765)
                     /gene="asp4"
                     /locus_tag="VVR63_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory secretory system protein Asp4"
                     /protein_id="HEU6129302.1"
                     /translation="MSEEDLFYKDVEGRMEELKQKPIKKEKETRGEKISKTFSLLLGL
                     MILIGLLFTLLGILR"
     gene            complement(767..2104)
                     /gene="gtfB"
                     /locus_tag="VVR63_001286"
     CDS             complement(767..2104)
                     /gene="gtfB"
                     /locus_tag="VVR63_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system glycosylation chaperone
                     GtfB"
                     /protein_id="HEU6129303.1"
                     /translation="MIELYDRYSHESRDLHESLVATGLSQLGVVIDADGFLPDGLLSP
                     FTYYLGYEDGKPLYFNQVPVSDFWEILGDNQSACIEDVTQERAVIHYVDGMQARLVKQ
                     VDWKDLEGRVRQVDHYNRFGACFAKTTYSADSEPIMTVYQDVNGQQVLLENHVTGDIL
                     LTLPGQSMRYFANKVEFITFFLQDLEIDTSQLIFNTLATPFLVSFHHPDKSGSDVLVW
                     QEPLYDAIPGNMQLILESDNVRTKKIIIPNKATYERALELTDEKYHDQFVHLGYHYQF
                     KRDNFLRRDALILTNSDQIEQVEAIAGALPDVTFRIAAVTEMSSKLLDMLRYPNVVLY
                     QNASPQKIQELYQLSDIYLDINHSNELLQAVRQAFEHNLLILGFNQTVHNRLYIAPDH
                     LFESSEVAALVETIKLALSDVDQMRQALGKQGQHANYVDLVRYQETMQTVLGG"
     gene            complement(2097..3608)
                     /gene="gtfA"
                     /locus_tag="VVR63_001287"
     CDS             complement(2097..3608)
                     /gene="gtfA"
                     /locus_tag="VVR63_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system glycosyltransferase GtfA"
                     /protein_id="HEU6129304.1"
                     /translation="MTIYNINLGIGWASSGVEYAQAYRAGVFRKLNLSSKFIFTDMIL
                     ADNIQHLTANIGFDDNQVIWLYNHFTDIKIAPTSVTVDDVLAYFGGEESHREKNGKVL
                     RVFFFDQDKFVTCYLVDENKDLVQHAEYVFKGNLIRKDYFSYTRYCSEYFAPKDNVAV
                     LYQRTFYNEDGTPVYDILMNQGKEEVYHFKDKIFYGKQAFVRAFMKSLNLNKSDLVIL
                     DRETGIGQVVFEEAQTAHLAVVVHAEHYSENATNEDYILWNNYYDYQFTNADKVDFFI
                     VSTDRQNEVLQEQFAKYTQHQPKIVTIPVGSIDSLTDSSQGRKPFSLITASRLAKEKH
                     IDWLVKAVIEAHKELPELTFDIYGSGGEDSLLRDIIANHQAEDYIQLKGHAELSQIYS
                     QYEVYLTASTSEGFGLTLMEAIGSGLPLIGFDVPYGNQTFIEDGQNGYLIPSSSDHVE
                     DQIKQAYAAKICQLYQENRLEAMRAYSYQIAEGFLTKEILEKWKKTVEEVLHD"
     gene            complement(3620..5992)
                     /gene="secA2"
                     /locus_tag="VVR63_001288"
     CDS             complement(3620..5992)
                     /gene="secA2"
                     /locus_tag="VVR63_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system translocase SecA2"
                     /protein_id="HEU6129305.1"
                     /translation="MFRRLGQDFQLRKVKKILKQINALKGKMSSLSDQELVAKTVEFR
                     QRLSEGESLDDILVEAFAVVREADKRILGMFPYDVQVMGAIVMHYGNVAEMNTGEGKT
                     LTATMPVYLNAFSGEGVMVVTPNEYLSKRDAEEMGQVYRFLGLTIGVPFTEDPKKEMK
                     AEEKKLIYASDIIYTTNSNLGFDYLNDNLASNEEGKFLRPFNYVIIDEIDDILLDSAQ
                     TPLIIAGSPRVQSNYYAIIDTLVTTLVEGEDYIFKEEKEEVWLTTKGAKSAENFLGID
                     NLYKEEHASFARHLVYAIRAHKLFTKDKDYIIRGNEMVLVDKGTGRLMEMTKLQGGLH
                     QAIEAKEHVKLSPETRAMASITYQSLFKMFNKISGMTGTGKVAEKEFIETYNMSVVRI
                     PTNRPRQRIDYPDNLYITLPEKVYASLEYIKQYHAKGNPLLVFVGSVEMSQLYSSLLF
                     REGIAHNVLNANNAAREAQIISESGQMGAVTVATSMAGRGTDIKLGKGVAELGGLIVI
                     GTERMESQRIDLQIRGRSGRQGDPGMSKFFVSLEDDVIKKFGPSWVHKKYKDYQVQDM
                     TQPEVLKGRKYRKLVEKAQHASDSAGRSARRQTLEYAESMNIQRDIVYKERNRLIDGS
                     RDLEDVVVDIIERYTEEVAADHYASRELLFHFIVTNISFHVKEVPDYIDVTDKTAVRS
                     FMKQVIDKELSEKKELLNQHDLYEQFLRLSLLKAIDDNWVEQVDYLQQLSMAIGGQSA
                     SQKNPIVEYYQEAYAGFEAMKEQIRADMVRNLLMGLVEVTPKGEIVTHFP"
     gene            complement(5985..6425)
                     /gene="asp3"
                     /locus_tag="VVR63_001289"
     CDS             complement(5985..6425)
                     /gene="asp3"
                     /locus_tag="VVR63_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein Asp3"
                     /protein_id="HEU6129306.1"
                     /translation="MIITQRQSIHWGEVGGTYMYGTTVSYYPDKSVRLYNPLLPSGEI
                     LKTWFSSVNYQAARTQPQLPLLKRKQEYQLSLVFDCQPENGVYTKITFFDRYGDILEK
                     KVEKAKDFIFTYPEDSYTYQVSLLSAGFESLTFYHFSIKEIRSV"
     gene            complement(6422..7957)
                     /gene="asp2"
                     /locus_tag="VVR63_001290"
     CDS             complement(6422..7957)
                     /gene="asp2"
                     /locus_tag="VVR63_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein Asp2"
                     /protein_id="HEU6129307.1"
                     /translation="MSKELNILQIGLANWENHYDIPENMSWYHFYPNSSKALREIIEK
                     EDINRFHAVLIEDGQYSRDLFSYVKYFEPYTLFYNQNLQINDREVVDFLKKRCAQAID
                     FLSPQQLINDLSKSLFGGGYGDKLFPPTIQVNPNFTGAISYQGLDYVSLEGEFGQDFA
                     QLAYWAYNIMVQKTLPIELWLEYEKEGNCDFRLVIRKMWSGSVDDFFEEVIVSEKDLE
                     QALFMDSRDGDYFLSISVEARGRGTIKLGNLHQRWSRKQFGKFVLGGNILHDSKRDEI
                     NYFFHPGDFKPPLTVYFAGYRPAEGFEGYFMMKTLGCPFILFSDPRLEGGAFYLGTDE
                     LEGKVKDMITHYLDYLGFDHKDLILSGLSMGTFPALYYGASFEPHAIIVGKPLANLGT
                     IASRGRLDAPGVSNLAFDCLIHHTGGTSSQDMTELDQRFWKIFKQANFSKTTFGLSYM
                     KDEEMDPQAYEQLVSYLCNTGAKILSKGTAGRHNDDTDTNISWFLHFYRMVLETGFGR
                     EKR"
     gene            complement(7941..9521)
                     /gene="asp1"
                     /locus_tag="VVR63_001291"
     CDS             complement(7941..9521)
                     /gene="asp1"
                     /locus_tag="VVR63_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein Asp1"
                     /protein_id="HEU6129308.1"
                     /translation="MYYFIPAWYGSERTWHADITPWYFSHFRLEFDDTFHQIRLFQEQ
                     DIDSRLLVLAYQPHLRYFLYRHGVLETDTYSVFDVMQDFHNLHTQVLSIRDIEWDDDC
                     EFIYSPFTIIVQKNGKKFAKVEHGVEGFISDIQYFEPNGQIHMHHIMDDRGFVSSIIF
                     FEDGQAAYQEYLNPKGVWQFRERLKEGGQVEVNPILGYRFKMLTYQNMGDLVAEFFEN
                     YLQTYVKDQDIFMLPSHSHHDQLVLDRLPSTNPKLLSLFIGRNPQDTFRDLDVTFEKS
                     DLILVDREDSLRLLQELYPERMHQCYHLSSFDTRLRLGRSQTKKESIIYFQLDFEQGI
                     DNQALLQVLSFVAENKDTEVIFGAFAASQEQMNEVEGIVESFIQENIQSENLGKAIDY
                     GDAENPLEENQHQDLRLQFVNLNDELDLIKTLEFVRLIVDLNRHPHLYTQIAGISAGI
                     PQINLVETVYVEHLKNGYLLADVTEFSKAAHYYTDRLKEWNESLIYSIDKIKEHTGQQ
                     FLGKLEKWIEEVKNVKGT"
     gene            complement(9531..10748)
                     /gene="secY2"
                     /locus_tag="VVR63_001292"
     CDS             complement(9531..10748)
                     /gene="secY2"
                     /locus_tag="VVR63_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein translocase subunit
                     SecY2"
                     /protein_id="HEU6129309.1"
                     /translation="MTKIYSSITVKKGLFTLFLLFIYVLGSRITLPFVDLNSKDFLGG
                     STAYLAFSAALTGGNLRSLSIFSVGLSPWMSAMILWQMFSYSKKLGLSSTAIEIQDRR
                     RMYLTLLIAVIQSLAVSLSLPVQSSYSVILVVLMNTLLLIAGTIFLVWLSDLNASMGI
                     GGSIVILLSSIVLNIPQDVIETFKLVHIPTGIVLLLVFMTIIFSYLLALMYRARYLVP
                     VNKIGLHNRFKRYSYLEIMLNPAGGMPYMYVMSFLSVPAYLFTLLGFIFPNHSGLAAL
                     SKEFMVGKPLWVYVYISVLFLFSIIFAFVTMNGEEIADRMKKSGEYIYGIYPGADTSR
                     FINRLVLRFSVIGGLFNVVMAGGPMLFVLFDEKLLRLAMIPGLFMMFGGMIFTIRDEV
                     KALRLNDTYRPLI"
     gene            complement(10805..11482)
                     /locus_tag="VVR63_001293"
     CDS             complement(10805..11482)
                     /locus_tag="VVR63_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEU6129310.1"
                     /translation="MGISVAKGEYITIVDSDDIVKENMIETLYQQVQEKDADVVIGNY
                     YNYDESDGNFYFYVTGKDFCVEELAIQEIMNRQAGDWKFNSSAFILPTFKLIKKELFN
                     EVHFSNGRRFDDEATMHRFYLLASKIVFINDNLYLYRRRSGSIMRTEFDLSWARDIVE
                     VFSKKISDCVLAGLDVSVLRIRFVNLLKDYKQTLEYHQLTDTEEYKDICFRLKLFFDA
                     EQRNGKS"
     gene            complement(11467..11709)
                     /locus_tag="VVR63_001294"
     CDS             complement(11467..11709)
                     /locus_tag="VVR63_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU6129311.1"
                     /translation="MSELISVVVPIYNTGKYLVECVEHILKQTYQNIEIILVDDGSTD
                     NSGEICDAFMMQDNRVRVLHQENKGGQHKLKIWGLV"
     gene            complement(11709..12905)
                     /locus_tag="VVR63_001295"
     CDS             complement(11709..12905)
                     /locus_tag="VVR63_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HEU6129312.1"
                     /translation="MRKSIVLAADNVYLIPLETTIKSVLYHNRDVDFYILNSDIAPEW
                     FKLLGRKMEVVNSTIRSVHIDKELFESYKTGPHINYASYFRFFATEVVESDRVLYLDS
                     DIIVTGELATLFEIDLKGYSIGAVDDVYAYEGRKSGFNSGVLLMDVAKWKEHSIVNSL
                     LELAAEQNQVVHLGDQSILNIYFEDNWLALDKTYNYMVGVDIYHLAQECERLDDNPPT
                     IVHYASHDKPWNTYSISRLRELWWVYRDLDWSEIAFQRSDLNYFERSNQSKKQVMLVT
                     WSADIKHLEYLVQRLPDWHFHLAAPCDCSEELTSLSQYTNVTVYQNVLHSRIDWLLDD
                     SIVYLDINTGGEVFNVVTRAQESGKKIFAFDITRKSMDDGLYDGIFSVERPDDLVDRM
                     KNIEIE"
     gene            complement(12914..14134)
                     /locus_tag="VVR63_001296"
     CDS             complement(12914..14134)
                     /locus_tag="VVR63_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 8"
                     /protein_id="HEU6129313.1"
                     /translation="MLQDKKSVVFAGDYAYIRQIETAMKSLCRHNSHLKIYLLNQDIP
                     QEWFSQIRIYLQEMGGDLIDCKLIGSQFQMNWSNKLPHINHMTFARYFIPDFVTEDKV
                     LYLDSDLIVTGDLTDLFELDLGENYLAAARSCFGAGVGFNAGVLLINNKKWGSETIRQ
                     KLIDLTEKEHENVEEGDQSILNMLFKDQYSSLEDQYNFQIGYDYGAAAFKHQFIFDIP
                     LEPLPLILHYISQDKPWNQFSVGRLREVWWEYSLMDWSVILNEWFSKSVKYPSKSQIF
                     KLQCVNLTNSWCVEKIDYLAEQLPEVHFHIVAYTNMANELLALTRFPNVTVYPNSLPM
                     LLEQIVIASDLYLDLNHDRKLENAYEFVLKYKKPMIAFDNTCSENLSEISYEGIYPSS
                     IPKKMVAAIRSYMR"
     gene            complement(14159..15043)
                     /locus_tag="VVR63_001297"
     CDS             complement(14159..15043)
                     /locus_tag="VVR63_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU6129314.1"
                     /translation="MKDLISVIVPVYNVEPFISSCLDSLSKQIYQNFEVLLVNDGSTD
                     NSGAICREYADRDSRFHYFEKENAGVADARNFGIERSKGDYITFVDSDDWVTEEYLSI
                     LIETLKEQHSEIVVSTYSTYNESDGLFYIHVFDSDYYVKNYNSKLLMEELPLLERYDM
                     SFLTSWGILFKRELFQEVQFPFGRVCEYIGTNYKLFMQVEKVTYINKVLYWYRVGKEG
                     LSNSYSPKMMRDDCDFRLERIAVLALKGYDVSKYLDQMKFYLKYRHDIAIQRELKENV
                     ETRHLEMLDYLLNGNKYN"
     gene            complement(15040..17493)
                     /locus_tag="VVR63_001298"
     CDS             complement(15040..17493)
                     /locus_tag="VVR63_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001044150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_1767 family glycosyltransferase"
                     /protein_id="HEU6129315.1"
                     /translation="MIKTIVLAGDRNYIRQLETTIKSILYHNRDVKIYILNQDIMPDW
                     FRKPRKIARMLGSEIIDVKLPEQTVFQDWEKQDHISSITYARYFIADYIQEDTVLYLD
                     SDLIVNTSLEKLFSICLEEKSLAAVKDTDGITFNTGVLLINNEKWRQEKLKERLIEQS
                     IVTMKEVEEGRFEHFNGDQTIFNQVLQDDWLELGRAYNLQVGHDIVALYNNWQEHLAF
                     NDKPVVIHFTTYRKPWTTLTANRYRDLWWEFHDLEWNQILQHHLGEFELISPLDKEFS
                     CLTLTNSQDLEGIEELVTALPEVVFHIAAWTDMGDKLKKLAVYNNVRLHPQIVPPVLD
                     KLKKSTNLYLDINHGSADENFLKSLQEQEKTLLAFQSTQHGELGQIVFENGKVSFMID
                     TIKDFKKNGHLTCFRQLPSLTCLTFTASQDIEQLDYLAGQLPNVVFQVAAWTAMGPKL
                     YDLSNRYPNIQLYPAISRDKLDELKEKMDAYLDINLLTSTSDIVAEMAHLSKPILAFY
                     KSQNGNNGQRLYSSEHPERMLADLQKLITKDMLEKPLDIIQVKGIDETLDYIIEHNSS
                     LVRFGDGEVNLMWGLPIPYQNHDLELANQLKHIVGLESDEKLVVCLPDAFDDRFVFTW
                     WATPFWKEHMNVYMDFYKELCKGSWYGSTFISRPYIDYEDKSKAKGQFEKLKSIWENR
                     DILIVEGITSRSGVGNDLFDKVKSVKRIICPSHNAYSVVDNIQEEIMKHAEGRLILCM
                     LGPTAKVLSYNLCQMGYQVLDVGHIDSEYEWMKMGAKTKVKFSHKHTAEHNFDQDIEF
                     IDDETYNSQILVDLSKREV"
     gene            complement(17503..18513)
                     /locus_tag="VVR63_001299"
     CDS             complement(17503..18513)
                     /locus_tag="VVR63_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEU6129316.1"
                     /translation="MKLHLTNLYGMAGDSTVILAQNAVQKIASQLGFREVGIYFYNIA
                     SDSPSEMNKRLDGIMASISIGDILVFQSPTWNGFEFDRLLFDKLKDMQVKIICFIHDV
                     VPLMFDSNYYLMKDYMYMYNLSDVLIVPSERMKTRLMEEGLTTKKILVQGMWDHPHDL
                     SLYTPAFKKELFFAGSLERFPDLQNWSQDTPLRVFSNKGEASSSARNLSIEGWKKDEE
                     LLLELSKGGFGLVWGTHQNEGESNQYYTLNISHKVSTYLTAGIPVIVPSSLSTAEFIV
                     DQGLGFVANSLEEVHEIVDKMNLQEYQEMTNRIKTFSYLLKEGYFTKKLLVDAIYHLG
                     VE"
     gene            complement(18542..19417)
                     /locus_tag="VVR63_001300"
     CDS             complement(18542..19417)
                     /locus_tag="VVR63_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000426741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU6129317.1"
                     /translation="MADELISIVVPIYNVENYLRMCLDSIQNQTYQNFECLLINDDSP
                     DHSSKICEEFVEKDSRFKYFEKANGGLSSARNLGIECSGGAYITFVDSDDWLEHDALD
                     RLYGALKKENADISIGRYNSYDETRYVYMTYVTDPDDSLEVIEGKAIMDREGVEEVRN
                     GNWTVAVLKLFKRELLQDLPFPIGKIAEDTYWTWKVLLRASRIVYLNRCVYWYRVGLS
                     DTLSNTWSEKRMYDEIGAREEKIAILASSDYDLTNHILIYKNRLQRVIAKLEEQNMQF
                     TEIYRRMMEKLSLLP"
     gene            complement(19422..20636)
                     /locus_tag="VVR63_001301"
     CDS             complement(19422..20636)
                     /locus_tag="VVR63_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HEU6129318.1"
                     /translation="MNTKSIVFNADNDYVDKLETAIKSICCYNNCLKFYVFNDDIASE
                     WFLMMNKRLKTIQSEIVNVKIVDHVLKKFHLPLKNLSYATFFRYFIPNFVKESRALYL
                     DSDIIVTGSLDYLFDIELDGYALAAVEDSFGDVPSTNFNSGMLLVNVDTWRDEDACSK
                     LLELTNQYHETAYGDQGILNMLFHDRWKRLDRNFNFMVGMDSVAHIEGNHKWYEISEL
                     KNGDLPSVIHYTGVKPWEIISNNRFREVWWFYNLLEWSDILLRKDIISRSFEELVYSP
                     KAHTAIFTASCEMEHVEYLIENLPEVHFSILAHTYFASSVVALLRYSNVTIYPCFSPF
                     DYRKILDNLDFYLDINHYKEVDNIVSVVQQLSKPIFTFENTSHDIGNQTNIFSSTEPN
                     KMVEAIRQFIGE"
     gene            complement(20943..23027)
                     /locus_tag="VVR63_001302"
     CDS             complement(20943..23027)
                     /locus_tag="VVR63_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000341103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEU6129319.1"
                     /translation="MDDKITVIVPVYNVENYLRKCLDSIITQTYKNIEIVVVNDGSTD
                     ASGEICKEFSEMDHRILYIEQENAGLSAARNTGLNNMSGNYVTFVDSDDWIELDYVET
                     LYKEITEYQADIAVGNYYSFNESEGMFYFHISGDSYYEKVYDNVSIFENLYETQEMRS
                     FALISAWGKLYKARLFEQLRFDMGKLGEDGYLNQKVYLLSEKVIYLNKSLYAYRIRKG
                     SLSRIWTEKWMHALVDAMSERITLLANMGYPLEKHLAIYRQMLEFSLSNGQASGLSDT
                     ATYKEFEMKQRLLNQLSRQEESEKKAIVLAANYAYVDQVLTTIKSICYHNRSIRFYLI
                     HSDFPNEWIKQLNKRLEKFDSEIINCRVTSEQISCYKSDISYTVFLRYFIADFVQEDK
                     ALYLDCDLVVTKNLDDLFATDLQDYRLAAVRDFGGRAYFGQEIFNAGVLLVNNAFWKK
                     ENMIQKLIDVTNEWHDKVDQADQSILNMLFEHKWLELDFDYNHIVIHKQFADYQLPEG
                     QDYPAIIHYLSHRKPWKDLAAQTYREVWWYYHGLEWTELGQNHHLHPLQRSHIYPIKE
                     PFTCLIYTASDHIEQIETLVQSLPDIQFKIAARVIVSDRLAQMTIYPNVTIFNGIHYL
                     VDVDNELVETSQVLLDINHGEKTEEIINQFARLGKTILSFENTKTYEAGQEAYAVDQV
                     QAMIEKLREISK"
     gene            complement(23088..>23908)
                     /locus_tag="VVR63_001303"
     CDS             complement(23088..>23908)
                     /locus_tag="VVR63_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEU6129320.1"
                     /translation="ASASTSASASASTSASASASTSASESASTSASVSASTSASASAS
                     TSASESASTSASASASTSASASASTSASASASTSASASASTSASESASTSASESASTS
                     ASASASTSASESASTSASESASTSASASASTSASASASTSASASASTSASASASTSAS
                     ASASTSASASASTSASASVSASTSASESASTSASASALASTSASASASTSVSNSANHS
                     NSQVGNTSGSTGKSQKELPNTGTESSIGSVLLGVLAAVTGIGLVAKRRKRDEEE"
BASE COUNT         7676 a         5057 c         3684 g         7491 t
ORIGIN      
        1 ctatctacaa cctcaaaacc gtgttttgag ctgacttcgt cagttctatc tacaacctca
       61 aaacagtgtt ttgagctgac ttcgtcagtt ctatccacaa cctcaaaaca gtgttttgag
      121 ctgacttcgt cagttctatc tacaacctca aaacggtgtt ttgagctgac ttcgtcagtt
      181 ctatctacaa cctcaaaacg gtgttttgag ctgacttcgt cagttctatc tacaacctca
      241 aaaccgtgtt ttgagcagcc tgcggctagc ttcctagttt gctctttgat tttcattgag
      301 tataaaaaag aaaacttcag accaatccac aaaaggtgaa tatctgaagt tttcttttat
      361 ttataagtaa tcaccataaa ggttaatagt agaacaaata aagccaaact caccaataaa
      421 gtgagcacct tgaccaaggt gttgctctgc cagtagcttg gtttaccaat attactagtg
      481 gcatccatgg aaaatagttg attttgacgg ggttgtatag ttaccaatac aatcaaagca
      541 agagatagga taatagctaa aacaattagt atttcaatca tagatctacc tcaaaattcc
      601 cagcaaagta aagagcaaac caatcagaat catcaaaccc agtaaaagtg aaaaagtctt
      661 actaatcttt tcccctcggg tttctttttc cttcttgatg ggtttttgtt tcaactcttc
      721 catgcggcct tcaacgtctt tgtaaaataa atcttcctct gacatgttag cctcctaaaa
      781 cagtttgcat ggtttcctga tatctcacca agtcaacata atttgcatgt tggccttgtt
      841 tgccaagtgc ctgacgcatt tgatcaacat ctgaaagggc caatttaatg gtctcaacca
      901 aagcagcaac ttcactactt tcaaatagat ggtctggagc gatataaagt ctattgtgca
      961 ccgtctgatt aaagccaaga atcaagagat tgtgctcaaa ggcctgacgc actgcctgta
     1021 gtaactcatt actgtggttt atatccaagt aaatatccga cagttgatac agctcctgaa
     1081 tcttctgtgg actagcattc tggtaaagga ccacattagg atagcgaagc atgtctaaga
     1141 gcttagaaga catctctgtc accgctgcaa tacggaaagt gacatcaggc aaggctcctg
     1201 cgattgcttc tacttgctca atctgatctg aattggtcaa gattaaggca tctcgtctta
     1261 ggaaattatc acgtttgaac tggtaatgat aacccaagtg cacaaactga tcatggtatt
     1321 tctcgtcagt taactctaaa gcgcgctcat aagtcgcctt atttggaatg atgatcttct
     1381 tagtacgcac attatcactt tccaaaatca actgcatatt acctggaatg gcatcataga
     1441 gaggttcctg ccataccaag acatccgagc cagatttatc tggatgatgg aaggaaacca
     1501 agaaaggagt cgctagagta ttaaagataa gctgactggt atctatttcc aaatcttgca
     1561 aaaagaaggt gataaattca actttatttg caaagtaacg catggactga ccaggcaaag
     1621 tcaataagat atcacccgtc acatggtttt ccagtaaaac ttgttggcca ttgacatctt
     1681 ggtaaactgt cataatcggc tcgctatctg cgctataagt ggttttagca aagcaagcac
     1741 caaagcgatt gtagtggtca acctgacgta ctcgaccttc taggtctttc cagtctacct
     1801 gtttaaccaa gcgagcctgc attccatcaa cataatgaat gacagccctc tcctgcgtca
     1861 catcttcaat acaagcagac tgattatctc ctaaaatttc ccaaaaatct gaaacgggaa
     1921 cttggttaaa atagagaggt tttccatcct cgtaacctag ataataggta aaaggagaaa
     1981 gcagaccatc aggcagaaaa ccatctgcat cgatgaccac tccaagttga gaaagaccag
     2041 tagcgactag actttcatgt aaatctcgac tttcatgact ataacgatca taaagttcaa
     2101 tcatggagca cctcctctac tgttttcttc cacttttcta aaatttcttt ggtcaagaag
     2161 ccttctgcaa tttggtaaga ataggcacgc atagcttcca aacgattttc ttgatacaat
     2221 tgacaaatct tagcggcata agcttgcttg atttggtctt ctacatggtc agatgaactt
     2281 ggaatcaaat aaccattttg cccatcctct ataaaggtct gattaccata aggcacatca
     2341 aaaccaatta gaggtagacc tgaaccaata gcttccatca aggtcagacc aaatccttcg
     2401 ctggtagaag ccgttaagta gacctcatac tggctataaa tctgcgaaag ttccgcatgc
     2461 cccttgagtt ggatatagtc ctctgcctga tgatttgcaa taatgtctct aagcagagaa
     2521 tcttctccac cactaccata gatatcaaag gttagttccg gtaactcctt atgagcttca
     2581 atcacagctt tcacaagcca atcaatgtgc ttttctttgg caagacgtga agccgtaatc
     2641 aatgaaaatg gtttgcgccc ttgacttgaa tctgtcaagg aatcaatact gcctacagga
     2701 atggtaacaa tctttggctg atgctgagta tatttggcaa attgctcttg tagaacttca
     2761 ttttgtctat cagtagacac gataaagaag tcaaccttat ctgcattggt aaactgatag
     2821 tcataatagt tattccaaag gatgtagtcc tcatttgtag cattttcact ataatgctcc
     2881 gcatgaacaa ctaccgctaa atgtgctgtc tgtgcttcct caaacacaac ctgaccaatg
     2941 cctgtctccc tatcgagaat gaccaaatca gacttattca aattcaaaga tttcataaag
     3001 gcacgcacaa aagcttgctt tccatagaaa atcttatcct tgaaatgata aacttcttcc
     3061 ttcccttgat tcatcaagat atcatagact ggagtcccgt cttcattata aaaagttcgt
     3121 tggtataaga ctgcaacatt gtccttggga gcaaaatact cgctacaata acgcgtataa
     3181 gaaaagtaat ccttccgaat caggtttccc ttaaaaacat actcggcatg ttgaaccaag
     3241 tccttgttct catcaaccaa ataacaggtt acaaacttat cttggtcaaa aaagaataca
     3301 cgtaaaacct tgccattttt ttctctgtga ctttcttcac caccaaagta agccaagaca
     3361 tcatccactg tcacgctagt aggtgcaatt ttgatatctg tgaaatgatt ataaagccag
     3421 ataacctgat tatcatcaaa accaatattg gctgttaagt gctgaatatt atcggctaaa
     3481 atcatatctg taaagataaa cttagaggac agatttaatt tccgaaaaac accagcacga
     3541 taggcttgag cgtattcaac accgctacta gcccaaccaa ttcctaaatt tatattgtaa
     3601 attgtcatat tttctcctct tatggaaaat gagtcacgat ttcacctttt ggagtgacct
     3661 caaccagccc catcaggaga ttacgcacca tatccgcacg gatttgttct ttcatagctt
     3721 caaagcccgc gtaggcttct tgatagtact ctacgattgg atttttctga ctagcagatt
     3781 gaccaccgat agccatggat agctgttgta gatagtctac ctgctctacc cagttgtcat
     3841 caatggcttt aagcagtgaa agtcgtaaaa actgttcata taagtcatgt tgattaagta
     3901 attctttctt ttcagaaagt tctttatcaa tcacctgctt cataaagcta cgaactgcag
     3961 ttttgtcagt tacatctata taatctggaa cctctttaac atgaaaacta atattggtca
     4021 caataaagtg aaacaataat tcacgactag catagtgatc agccgctacc tcttctgtat
     4081 atctctcaat gatatccaca acaacatcct ctaagtcacg agaaccatct attagacgat
     4141 ttctctcttt atagactata tcccgttgta tattcatact ttcagcatac tccagagtct
     4201 gacgacgtgc tgaacgtcca gcactatcac tggcatgctg agccttttcg actagtttcc
     4261 ggtatttacg acctttcaat acttccggtt gagtcatatc ttgaacctga tagtctttgt
     4321 actttttatg cacccaagat ggaccaaatt tcttgataac atcatcctct aaggatacaa
     4381 aaaatttact cataccagga tctccctgac gaccagaacg gccacgaatt tgtaggtcga
     4441 tccgctgact ttccatccgc tcagtcccaa taacaatcaa gcccccaagc tctgcgactc
     4501 ctttaccaag cttgatatcc gtaccacgtc ctgccataga ggtagccact gtcacagccc
     4561 ccatctgacc tgactcggag ataatctgag cctcacgcgc cgcattatta gcatttagga
     4621 cattatgggc aatcccttca cgaaacaaga gagacgaata gagttgagac atttcaactg
     4681 agcctacaaa aacgagtaaa ggatttccct tagcatggta ttgcttgatg tactccaagg
     4741 atgcatacac tttttcaggt aaagtgatat atagattatc tggatagtca atccgttgtc
     4801 tcggacgatt ggttggaatg cgtactacag acatattgta agtttcaata aactcttttt
     4861 ccgcgacctt acctgtccct gtcataccag atatcttatt aaacatctta aaaagactct
     4921 gataggtgat cgaggccata gcccgcgtct caggagataa tttgacatgt tccttggctt
     4981 caatagcctg atggagacct ccttgaagtt tagtcatttc cattagacgc cctgttccct
     5041 tatcaaccag taccatctca tttccacgaa tgatatagtc cttatcttta gtaaagagct
     5101 tatgagctcg aatcgcataa accaaatgac gagcaaaaga cgcatgctct tccttgtata
     5161 aattatcaat ccctaggaaa ttctcagcag acttggcccc cttagtagtg agccaaacct
     5221 cctctttctc ctctttaaag atataatcct ctccttcgac caaggttgtt acaagtgtat
     5281 caatgatcgc atagtaatta gactgaacac gaggagaacc cgcaataatc agaggagttt
     5341 gtgcactatc aagcaagata tcatcaattt catcaataat cacatagtta aacggtcgta
     5401 aaaacttacc ttcttcattc gaggctaggt tatcatttag ataatcaaaa cctaaattac
     5461 tattggttgt gtagatgata tccgaagcat agataagctt cttttcttca gctttcatct
     5521 ccttctttgg atcttccgta aatggtacac caatggtcaa tcctagaaaa cgataaactt
     5581 ggcccatttc ctcggcatca cgctttgata aatactcatt aggagtcaca accatcactc
     5641 cttctcctga aaaagcgttc aaatagacag gcatggtagc tgtcaaggtc ttaccttccc
     5701 ccgtattcat ctcagcaaca tttccatagt gcatgacaat agctcccatg acttgaacat
     5761 cataaggaaa catccctaaa atccgcttat ctgcttcacg caccacagca aaagcttcaa
     5821 ccaaaatatc gtctagactt tctccctcgg aaagacgctg acgaaactct actgttttag
     5881 ctactaattc ttgatccgaa agagaggaca tcttgccttt cagggcatta atctgcttta
     5941 aaatcttttt cactttccta agctggaaat cttgacctaa acgtctaaac acttctgatc
     6001 tccttgatag aaaaatgata aaaagttaag gactcaaatc cagcacttaa aagagaaact
     6061 tgataagtat aactatcttc tggataagta aatatgaaat ctttcgcttt ttctaccttt
     6121 ttttctaaaa tatcaccata gcggtcaaaa aaagttatct tggtataaac tccattttca
     6181 ggctgacaat caaaaaccag tgatagttga tactcctgct ttctttttaa taagggaagc
     6241 tgaggttggg ttcgtgcagc ctggtaattg acactagaaa accaagtctt tagaatctca
     6301 ccagatggca atagaggatt atacagacga acacttttgt cagggtaata agatacagtt
     6361 gttccataca tataagtccc accaacttct ccccaatgaa tagactgtct ctgtgtaata
     6421 atcatctttt ctcccttcca aaaccagtct ctaagaccat tctataaaag tgcaaaaacc
     6481 aagaaatatt ggtatctgta tcatcattgt gtcgtccagc agttccttta gataaaatct
     6541 tcgcacctgt attacacaga taagacacta attgttcata ggcttgtgga tccatttctt
     6601 catctttcat ataggataaa ccaaaggttg tctttgaaaa atttgcttgt ttaaaaattt
     6661 tccaaaaacg ctgatccaac tccgtcatat cttgagaact tgtcccacct gtatgatgaa
     6721 ttaaacaatc aaaagctaag ttagagacac ccggtgcgtc caaacgtcca cgactagcta
     6781 tggttcctaa attagccaag ggcttaccaa ctatgatggc atggggttca aaagaagcac
     6841 cataatagag agccggaaac gttcccatag aaagacctga taaaatcaaa tccttatgat
     6901 caaagcctaa ataatcaaga tagtgagtga tcatatcctt tacttttccc tctagctcat
     6961 ccgttccgag ataaaaagct cccccctcta aacgtggatc agaaaataaa atgaagggac
     7021 atccaagcgt tttcatcata aagtaaccct cgaatccttc tgcaggtcga taacctgcaa
     7081 aatagacagt caaaggcggt ttaaaatcac ctggatggaa gaaatagttt atttcatcac
     7141 gcttggaatc atgtaggata tttccaccaa gtacaaactt accaaattgt tttcgactcc
     7201 atcgttggtg aagattacct agtttgatag ttccacgacc tcttgcttca acagatatcg
     7261 agagaaagta gtctccgtct cgactatcca taaaaagtgc ttgctccaag tctttttcag
     7321 atactattac ttcttcaaag aaatcatcaa cagacccact ccacatttta cggatgacca
     7381 aacgaaagtc acaattgcct tccttctcat attcaagcca caactcaata gggagtgttt
     7441 tttgcaccat aatattataa gcccaatagg caagctgggc aaaatcttgc ccaaactcac
     7501 cttccaaact gacataatcc aatccttgat aagaaatagc tcctgtaaaa tttggattga
     7561 cttgtatcgt cggaggaaag agtttatcac catacccacc gccaaaaaga gatttactta
     7621 aatcattgat tagttgttgg ggacttaaaa aatcaattgc ttgtgcacat cgttttttta
     7681 gaaaatccac aacctctcta tcatttattt gtagattctg gttatagaac aaagtataag
     7741 gttcaaaata ttttacatag gaaaataagt ctctggaata ctgaccatct tctattaaaa
     7801 ctgcatgaaa acggttaata tcctcttttt cgattatttc acgaagggct tttgatgaat
     7861 ttgggtaaaa atgataccaa ctcatatttt caggtatgtc atagtgattt tcccaattgg
     7921 caagtcctat ctgtaaaata ttaagttcct ttgacatttt taacctcctc tatccatttc
     7981 tctaattttc caagaaattg ttgtcctgtg tgctccttaa tcttatcaat tgaatatatc
     8041 aaggactcat tccactcctt caacctatct gtgtaataat gtgcagcctt agaaaattct
     8101 gtaacatctg ctaacaaata accatttttt aaatgttcaa catagacggt ttcaactagg
     8161 ttgatttgag gaattcctgc actaatccca gcaatctgtg tgtagagatg aggatgtcta
     8221 tttaaatcca caatcaaacg gacaaattct agtgttttta tcaaatctaa ctcatcattc
     8281 aagttaacaa actgtaagcg taagtcctgg tgttgatttt cttccagagg attttctgca
     8341 tcaccataat caatcgcctt tcccagattt tcggattgaa tgttttcttg gatgaaagac
     8401 tcaacaatcc cttcaacctc attcatttgc tcctgactag cagcaaaggc tccaaaaatc
     8461 acctcagtat ccttattttc agcgacaaag gacaagactt gaagcagagc ttgattatca
     8521 atcccctgct caaaatccag ttgaaaataa atgatggatt ctttcttagt ttggcttcgt
     8581 cccaatcgta atcgggtgtc aaaagatgat aaatgataac attgatgcat tcgttcagga
     8641 tacaactcct gcaacaatcg taaactatcc tctctatcca ccaaaatcaa atccgatttt
     8701 tcaaaagtta catctaaatc cctaaaggta tcttgaggat tacgtccaat gaacagactc
     8761 aacagtttag gattagtact aggtaaacga tctagtacca actggtcatg atgagaatga
     8821 gaaggaagca taaaaatatc ctgatccttc acatacgttt gcagataatt ctcaaaaaat
     8881 tctgccacca gatctcccat attttgatag gtaagcattt taaagcgata acccaaaatt
     8941 ggattgactt ctacctgtcc tccttctttt aaacgctctc taaattgcca aactccctta
     9001 ggattcaaat attcttgata ggctgcttgc ccatcttcaa aaaagataat gctcgataca
     9061 aaccctcgat catccatgat atggtgcata tgtatttgac cattcggttc aaaatactgt
     9121 atatcactga tgaagccttc aactccatgt tcaaccttag caaatttctt cccatttttt
     9181 tgaacgataa tcgtaaaggg actataaata aattcacagt catcatccca ctcaatatct
     9241 ctaatgctta aaacttgggt atggagatta tgaaaatctt gcataacatc aaaaacggaa
     9301 taagtatccg tttctaacac accatgtcta tataaaaaat aacgtagatg aggctggtaa
     9361 gctaatacta atagacgaga atctatatct tgctcttgaa agagccggat ctggtgaaag
     9421 gtatcatcaa actctagacg aaaatgagaa aaataccatg gagtgatatc tgcatgccat
     9481 gttctttctg acccatacca agctggaata aaataataca taaaagtctc ctaaatcaag
     9541 ggtctatagg tatcatttag ccttaaagcc ttgacctcgt ctctaatcgt aaaaatcatg
     9601 cccccgaaca tcataaataa gcctggaatc attgccaatc gtaataactt ttcatcaaac
     9661 aaaacaaaaa gcatgggacc acctgccata accacattaa agagaccacc tatgactgag
     9721 aaacgaagga ccaatcgatt aataaatcga ctagtatccg cacctggata aataccataa
     9781 atgtattctc cagatttttt catacggtct gcaatctctt ctccattcat cgtaacaaaa
     9841 gcaaaaatga tactaaataa aaataagacc gaaatataaa catagaccca caaaggctta
     9901 ccaaccataa attcctttga taaagccgct agccctgaat gattagggaa aataaatccc
     9961 aacaaggtga acaaataagc tggtacacta agaaaactca tcacatacat ataaggcatc
    10021 ccacctgcag gattcaacat gatttcgaga taagaatagc gtttaaatcg attgtgtaag
    10081 ccaattttat taacaggaac caaatagcga gctcgataca taagggcaag caagtaagaa
    10141 aatataatgg tcataaaaac aagcaagaga acaatccctg tagggatatg aaccagttta
    10201 aaagtttcaa taacatcctg agggatattt aaaacaatgc tggataggag gattacaata
    10261 gaacccccaa ttcccatgct agcatttaaa tctgacaacc aaaccagaaa aattgttcct
    10321 gctatcagca acaaggtatt cattagaaca accaaaatta ccgagtagga ggattgtact
    10381 ggcaagctca agctaactgc caaggattga atcacagcaa ttagcaaggt cagatacatt
    10441 cttcgacgat cttgaatttc aatcgctgta gaacttagcc ccaatttttt agaatatgaa
    10501 aacatctgcc acaaaatcat agctgacatc caaggggata atccaacaga aaaaattgac
    10561 aaacttctta gatttccacc tgtaagggct gctgaaaaag ctaggtaggc tgttgaacca
    10621 cctaagaaat ctttggaatt caaatcaaca aaagggagag taatacgact tcccaataca
    10681 tagataaaca gtagaaataa ggtaaataat ccttttttta ctgttataga cgaataaatc
    10741 ttagtcataa aacacgcccc tcaccttcat tgtttgtgat atggtaaata acaattcttt
    10801 tatttcaact tttaccattt ctttgttctg catcaaaaaa caactttaat ctgaaacaaa
    10861 tatctttata ttcctcagta tctgttaatt gatggtattc taaagtttgc ttataatctt
    10921 ttaaaagatt gacaaatcga atacgcagaa cggagacatc caaaccagcc aagacacaat
    10981 ccgatatttt cttagaaaac acttcaacaa tatctcttgc ccaggaaaga tcaaattccg
    11041 ttctcatgat gcttcctgaa cgtcttctat acagatagag attatcgttt ataaagacga
    11101 ttttagaggc taaaagataa aagcgatgca tagttgcttc atcatcaaag cggcgaccat
    11161 ttgaaaagtg aacttcattg aataattctt ttttaatcaa cttaaatgtc ggcaatataa
    11221 aggccgagct attgaatttc caatctcctg cttgacggtt cataatttct tgtatagcta
    11281 attcttcgac gcaaaaatct ttccctgtta cataaaaata aaaattcccg tcactttcgt
    11341 cataattata gtaattccct ataacaacat ctgcatcctt ttcttggact tgctgataaa
    11401 gagtttcaat catattttct tttacgatat catctgaatc aacaatcgtg atgtactctc
    11461 ccttagctac actaatcccc atatttttag cttgtgctgc ccccccttat tttcttgatg
    11521 caatactcgc acacgattat cttgcatcat aaaagcatca caaatttccc cagaattatc
    11581 cgtagaaccg tcatcaacta aaataatttc tatattttga taggtttgct tcagaatatg
    11641 ctcgacacac tccactaaat attttcccgt attgtatatc ggtaccacaa cactaattaa
    11701 ttcactcatt actctatctc tatattcttc attctatcca ctaaatcatc tggtctctcc
    11761 acagaaaaaa taccgtcata gagtccatca tccatacttt tacgtgtgat atcaaaagcg
    11821 aagattttct tgccactttc ttgtgccctt gtaactacat taaaaacctc tccacctgta
    11881 ttaatatcta aataaactat agaatcgtcc aatagccaat caattctact atgtaataca
    11941 ttttgatata ctgttacatt cgtatactgt gatagagagg tcagctcctc agaacaatca
    12001 cacggtgcag ccaaatgaaa atgccaatca ggtaaccgtt gtactaaata ctctaaatgt
    12061 tttatatctg cactccatgt cacaagcatc acttgttttt tagactgatt gcttctttca
    12121 aaataattta aatcggaacg ttgaaaagca atctctgacc aatccaaatc tctataaacc
    12181 caccataatt cacgtagtct agatatacta tatgtattcc aaggtttatc atgactagca
    12241 tagtgaacaa ttgtaggtgg attgtcatct agacgttcac attcttgagc aaggtgataa
    12301 atatcaacac ctaccatata attatatgtt ttatctaagg ctagccaatt atcctcaaaa
    12361 taaatattta aaatactctg atccccaaga tgaacaactt gattttgctc ggccgctaat
    12421 tccaataaac tattgacaat agagtgttct ttccattttg caacatccat taataaaact
    12481 ccagaattaa atccagattt tcgtccttca taggcataga catcatcaac agcaccaatt
    12541 gaatatcctt tgagatctat ctcaaacaaa gtagctagtt ccccagttac aatgatatcg
    12601 gaatccagat acaataccct atcagattca accacttctg tcgcaaaaaa tctaaagtaa
    12661 gaagcataat ttatatgagg tcctgtttta tagctttcaa aaagttcttt atcaatgtgt
    12721 acactgcgaa ttgtagaatt cacaacttcc atttttctcc ccaataattt aaaccattca
    12781 ggagctatat cactgttgag aatataaaaa tcaacatctc tattgtgata caatacagac
    12841 tttatagtcg tctctaaagg aataagatag acattatctg ccgctaatac tattgatttt
    12901 ctcatactgt tctctacctc atgtaagatc tgattgctgc aaccattttt ttcggaatgg
    12961 agcttggata gataccttca tatgaaatct cagaaagatt ttcagagcaa gtattgtcga
    13021 aagctatcat tggttttttg tacttaagca caaactcata tgcattttct aattttcgat
    13081 catgattcaa atccaaatac aaatctgaag ctattactat ttgttccaat aacattggta
    13141 aggaatttgg atatacggta acattaggaa aacgcgttaa agctagtagt tcatttgcca
    13201 tatttgtata agcaacaata tgaaaatgaa cttctggcaa ttgctccgcc aaataatcga
    13261 ttttctcgac acaccaagaa ttcgttaaat taacacattg caacttaaat atttgtgatt
    13321 tactaggata cttcacactc tttgaaaacc attcatttaa aataacagac caatccatca
    13381 aagagtattc ccaccaaact tctcttagac gtccaacaga aaattgattc caaggcttat
    13441 cctgagaaat atagtgtaaa attagtggca gtggttcgag cggaatatca aaaatgaatt
    13501 gatgtttaaa ggctgccgcc ccataatcat atcctatttg aaaattatat tgatcttcaa
    13561 gggaactata ttgatcttta aacaacatat tcaaaattga ctggtctcct tcttccacat
    13621 tctcatgttc tttttctgtt aagtcaatca atttttgtcg aatagtttca gatccccatt
    13681 ttttgttgtt aatcaagaga acaccagcat tgaagccgac tcctgctcca aagcaagaac
    13741 gagctgctgc caaataattt tcacctaagt ctaattcaaa caaatcggtc aaatcaccag
    13801 tcacaatcaa atcactatct agatagagaa ctttatcttc tgttacaaaa tctggaataa
    13861 aatagcgtgc aaatgtcata tgattgatat gaggtaattt attagaccaa ttcatttgaa
    13921 actgtgagcc aattaacttg cagtcaatca agtcgccccc catctcttgt aaatatattc
    13981 ttatttgact aaaccattcc tgaggaatgt cctgatttag cagataaatt ttcaaatgac
    14041 tattgtgtct acagagtgac ttcatcgccg tttcgatttg tcgaatataa gcgtaatcac
    14101 ctgcaaatac tacagatttc ttatcttgta acattttatc gtctctctat cttaattttc
    14161 agttatattt attaccattc aataaatagt ctaacatttc taaatgtctt gtttccacat
    14221 tctccttaag ttctcgttga attgcaatat catgacgata tttcaaatag aacttcatct
    14281 ggtctaaata tttactgaca tcatatcctt ttagcgctag cacggcaatt cgttctaacc
    14341 taaaatcaca atcatcacgc atcatcttcg gtgaataaga attagaaagt ccttctttcc
    14401 caaccctata ccaatacaaa actttattaa tataggttac tttctcaacc tgcataaata
    14461 atttataatt ggttcctata tactcacaca cccgaccaaa cggaaactga acttcttgaa
    14521 ataattccct tttaaataga attccccaag aagttaaaaa gctcatatca tacctctcta
    14581 ataaaggaag ttcttccatt agaagttttg aattataatt tttcacataa taatcggagt
    14641 caaatacgtg aatatagaat aagccatctg actcattata ggttgaataa gttgaaacaa
    14701 caatttcaga atgctgctcc ttcaaagttt ctataagaat tgataaatac tcttcagtaa
    14761 cccaatcatc tgagtctaca aaagtaatat aatctccttt agatctctcg attccaaaat
    14821 tacgtgcatc cgctacccca gcattttctt tttcgaaata gtgaaaacga ctatcacgat
    14881 cagcatactc tcgacatatt gctcctgaat tatctgtaga gccatcattt actaataaaa
    14941 cttcaaaatt ttgataaatc tgtttcgata aactgtctaa gcagctagaa ataaatggtt
    15001 ctacgttata aactggtact ataacactta ttaaatcttt catacttctc tttttgataa
    15061 atcaactaaa atctgactgt tataggtttc atcatcaata aattcaatat cttggtcgaa
    15121 attatgttct gcagtatgtt tatgagaaaa tttaacctta gttttagctc ccattttcat
    15181 ccattcatac tctgagtcaa tatggcctac atccaaaact tgatagccca tctggcatag
    15241 attataactc agaacttttg ctgtaggacc cagcatacat aaaatcagtc ttccttcagc
    15301 atgtttcata atttcctctt gaatgttatc gacaacggaa taagcattat gagatggaca
    15361 aataatccgt ttcacagatt tgaccttatc aaataaatca tttccaaccc cagagcgaga
    15421 tgtaatcccc tctacaatca gaatatccct attctcccaa atactcttta gcttttcaaa
    15481 ttgtcctttt gccttactct tatcttcata atcaatgtat ggacgcgaga taaaggtaga
    15541 gccataccat gaacccttac acaactcttt ataaaaatcc atataaacat tcatatgttc
    15601 tttccagaat ggtgtagccc accaagtaaa gacaaaacga tcgtcaaaag catcaggtaa
    15661 acaaaccact aatttctcgt cactctcaag acccacaata tgttttaatt ggttagctaa
    15721 ctctagatca tgattttgat aaggtatagg caaaccccac atcaaattga cttctccgtc
    15781 tccaaaacga actaaagaag agttgtgttc aataatataa tccaaggttt catctatccc
    15841 tttcacctgg attatatcaa gcggtttttc tagcatatcc ttagttatca atttttgcaa
    15901 atcagccaac attcgttcag gatgttcact tgaatacaac ctttggccat tattcccatt
    15961 ttgagattta taaaaggcta gtataggttt agatagatga gccatttctg caacgatatc
    16021 ggatgttgaa gtcagtaggt tgatatctaa ataagcatcc atcttctcct tcaactcgtc
    16081 tagcttatct ctagaaattg ccggatagag ctgaatatta ggataacgat tagacaaatc
    16141 atataatttt ggccccatag ctgtccaagc agcaacttga aaaacaacat ttggcaactg
    16201 tccagccaag taatccaatt gttcgatatc ctgagaagcc gtaaacgtta aacaagttaa
    16261 acttggaagt tgtcgaaaac aggtaagatg tccgtttttc ttaaaatctt taatcgtatc
    16321 aatcataaag gaaactttcc cattttcgaa aacgatttgt cctaactctc cgtgctgagt
    16381 cgattgaaaa gctagtagcg ttttttcttg ttcttgcaaa gattttaaaa agttctcatc
    16441 tgcactacca tgattgatat ccaaatatag atttgttgac tttttcagct tatctaatac
    16501 aggaggaaca atttgtggat gcaatctcac attattatat acagctaatt tttttaattt
    16561 atctcccata tccgtccaag ctgcgatatg aaataccacc tcaggtagag ctgtaactag
    16621 ctcttctatt ccttctaaat cttgggaatt cgttaaggtt aagcaagaaa attccttatc
    16681 tagaggcgat attagttcaa attctcccaa atgatgttgt aaaatctgat tccactccaa
    16741 atcatggaat tcccaccata aatcacgata acgattggct gtcaaggtgg tccagggttt
    16801 tctgtaggtc gtaaaatgaa tcaccactgg tttatcatta aaagccagat gttcctgcca
    16861 attgttatac aaagccacaa tatcatgccc tacttgtaaa ttataagctc gacctagttc
    16921 taaccaatca tcttgtaaga cctgattaaa aatcgtttga tcaccattaa aatgctcgaa
    16981 acggccttct tcaacttcct tcattgtaac aatgctctgt tcaattagtc gttcttttaa
    17041 tttctcttga cgccattttt cattgttgat taatagaaca cctgtattaa atgtaattcc
    17101 atctgtatct ttaactgctg cgagtgattt ttcttctaaa caaatactaa ataatttctc
    17161 taaagaagta tttacaatca aatcactgtc taaatataaa accgtatctt cttggatata
    17221 atctgcaata aaatatctag cataggtaat gctactaatg tgatcttgct tttcccaatc
    17281 ttgaaacaca gtttgttcag gtagtttaac atcgataatc tcactaccta acatgcgagc
    17341 tatttttcgt ggtttgcgaa accaatctgg cataatatct tgatttaaaa tataaatctt
    17401 aacatctcga ttgtggtata aaatagattt tatggttgtt tctaactgcc tgatgtaatt
    17461 acgatcacca gctaatacaa ttgttttaat catcttgttc tcttattcaa ctcccaaatg
    17521 gtaaattgca tctaccaata attttttagt aaaataacct tcttttagca aataactaaa
    17581 ggtttttatc cgattcgtca tttcttgata ttcttgtaga ttcattttat caactatctc
    17641 atgaacttcc tctagactat tcgccacaaa gcctaagcct tgatctacta taaattcagc
    17701 agttgacaag ctacttggta caatgactgg gatgcccgct gtcagatagg tactcacctt
    17761 atgagatata ttcaaggtat agtattggtt actttctccc tcattttgat gggttcccca
    17821 gacaaggcca aatccaccct ttgataattc tagcaacaat tcctcatctt ttttccatcc
    17881 ttcgatgctg agatttctag cactagaact agcttcccct ttatttgaaa atactctcaa
    17941 aggcgtatct tgagaccaat tttgtaagtc tggaaaacgc tctaaacttc cagcaaaaaa
    18001 aagttctttt ttaaaagcag gggtgtataa ggataaatca tgaggatgat cccacatccc
    18061 ttgaacaaga atcttcttag tcgtcaatcc ttcttccatc aggcgtgttt tcattctctc
    18121 tgatggcact atcaaaacat ctgatagatt atacatgtac atatagtctt tcatgagata
    18181 atagttacta tcaaacatga ggggaacaac atcatggata aagcaaataa ttttcacctg
    18241 catatccttt agcttgtcaa acaagagacg atcaaattca aagccattcc aggttggaga
    18301 ctgaaagact aaaatatccc caatagagat actggccata ataccatcca gacgcttatt
    18361 catttcagaa ggactatctg aagcaatgtt gtaaaaataa ataccaacct ctctaaatcc
    18421 cagttgacta gctatctttt gaacagcatt ttgagctaag ataaccgtac tatcaccagc
    18481 catgccgtat aaatttgtta aatgtaattt catattacgc tatctcattt tttattacta
    18541 tctacggaag taaagacaat ttttccatca ttcttctata aatctctgtg aactgcatat
    18601 tttgttcttc taattttgct atcactcttt gtaatctatt tttataaatc aaaatatgat
    18661 tggtcaagtc atagtctgaa cttgctaaaa tagctatctt ttcttcccta gccccaattt
    18721 catcatacat acgcttttca ctccatgtat tcgataaagt atcagataaa ccaacacggt
    18781 accagtaaac acaacgattc aaatagacta tcctcgaagc tcttagaagt accttccatg
    18841 tccagtaagt atcctctgca atttttccta taggaaatgg taaatcttgt agtaactctc
    18901 tcttgaataa cttcaagaca gctacagtcc agttcccatt tctgacttct tcgacacctt
    18961 ccctatccat gattgcttta ccttctatca cttccagaga atcatctgga tccgtaacat
    19021 aagtcatata cacatagcgt gtttcatcat aagaattata acgcccgata ctaatatctg
    19081 cgttttcctt tttcaaagca ccatataatc ggtctaaagc atcatgttcc aaccaatcat
    19141 cagagtctac aaaagtaatg tacgcccccc ccgaacattc aatacctagg ttacgagctg
    19201 atgaaagacc gccgtttgct ttctcaaaat atttgaaacg agaatctttc tctacaaatt
    19261 cttcacatat tttggatgaa tgatctggag agtcatcatt gattaataaa cactcaaaat
    19321 tttgatacgt ctgattctga atgctatcca aacacattcg caaataattc tcaacattgt
    19381 agattggaac tacaatacta attagttcgt ctgccataaa cttattctcc tataaattgt
    19441 ctaatagcct ctaccatttt gtttggttcg gttgaagaaa atatattagt ttgattgcct
    19501 atatcatgac tagtattttc aaaggtaaaa attggtttag atagttgttg aacaacggat
    19561 acaatattat ccacctcttt ataatgatta atatctagat aaaaatctaa attatccaaa
    19621 atttttcgat aatcaaatgg agaaaaacaa ggataaatcg taacattgct atatcttaat
    19681 aaagcaacga cactagacgc aaaatatgta tgtgctagta tagaaaaatg tacctctggt
    19741 aaattttcta tcaaatattc tacatgctcc atctcacaac tagctgtaaa aattgctgta
    19801 tgagctttag gactgtatac aagttcttcg aaactacgac taataatgtc ttttctcaat
    19861 aaaatatcag accattctaa cagattataa aaccaccaaa cttctctaaa gcgattattg
    19921 gaaattattt cccaaggttt taccccagta taatgtataa cactaggtaa atctccattt
    19981 ttcaactcag aaatctcata ccatttatga tttccttcta tgtgtgcgac gctatccatc
    20041 cccaccataa aattaaaatt tcggtctaat cttttccatc tatcatggaa taacatattt
    20101 aaaattcctt gatctccata tgctgtttca tgatattgat tggtcagttc taacagtttc
    20161 gaacaagcat cttcatctct ccaagtatct acattaacta ataacattcc ggagttaaaa
    20221 ttggtagaag gaacatcacc aaaagaatct tctactgctg ccaaggcata accatctagt
    20281 tctatatcaa ataaatagtc taaacttcct gtaacaatga tgtcagaatc taggtataaa
    20341 gcacgacttt ctttgacaaa attaggtata aaataacgaa agaaagtggc ataacttaaa
    20401 ttctttaacg gtaaatgaaa ctttttaaga acatgatcta caatctttac attaacgatt
    20461 tcagattgta tagtcttcaa tcgcttattc atcatcaaaa accactctga cgcaatatca
    20521 tcattaaata cataaaattt taaacaatta ttataacaac aaatagattt aattgcagtt
    20581 tctaatttat ctacataatc attatctgca ttaaaaacta tagattttgt attcattaac
    20641 ataatttcct tataataaat ttcgtatcaa acagctataa tatagaatca ttttcaccta
    20701 aaaagataat taatcacacc ctaatattgt actgacccca aaaagttaga ttttttctgt
    20761 ctaacttttg gggtgcagtt catattaaat atctttaggt ctatttatat tttataaagc
    20821 actctgatgt ttgaacaact ttcatatatg atgaacggag aaattttata aaaaataatc
    20881 caactcttca atctgatcac taaccgtcaa aatcagagca tctcctacta aatgattttt
    20941 cttcatttac ttatttctct taatttttca atcattgctt gaacttggtc aacagcatat
    21001 gcctcctgac ctgcttcata ggttttggta ttttcaaagg acaaaatagt ttttccaagt
    21061 cttgcaaatt gattgataat ttcctctgtt ttttcaccat gattaatatc taaaagtact
    21121 tgactggttt ctaccaattc attatcgaca tctaccaaat agtgaattcc gttaaatata
    21181 gtcacgtttg gataaattgt catctgagcc aatcgatcac taactattac tctagctgct
    21241 atcttaaact gaatatcagg caaggattga accaatgtct caatttgttc aatatggtct
    21301 gaggcagtat agattagaca agtgaaaggt tcctttattg gatagatgtg agatctttgt
    21361 aatggatgta aatgatggtt ttgtcccaat tctgtccatt caagcccatg atagtaccac
    21421 caaacttcac gataggtttg ggccgccaaa tctttccacg gtttccgatg agaaagatag
    21481 tgaataatag caggataatc ctgaccctca ggcaattgat aatcagcaaa ctgtttatga
    21541 atgacaatat gattataatc aaagtccaat tccaaccatt tatgttcaaa aagcatattc
    21601 aagatgctct gatctgcctg atccacctta tcatgccatt cattggttac atcaattaat
    21661 ttttggatca tattctcttt tttccaaaaa gcattgttta ccaagagaac accggcatta
    21721 aagatttctt gaccaaaata agctctgccc ccaaaatctc taacagcagc caaacgataa
    21781 tcttgtaagt ctgtagcaaa caagtcatcc agatttttcg ttacaactag atcacagtcc
    21841 aagtagaggg ccttgtcttc ttgcacgaaa tcagctatga aatagcgtaa aaagactgtg
    21901 taactaatat ccgatttata acatgaaatt tgctcagaag ttacccgaca attaataatt
    21961 tctgagtcaa acttctctaa gcgcttattt aattgcttaa tccattcatt tggaaaatcg
    22021 ctatgaatca gataaaaacg aatcgaacga ttatgataac aaatagactt gattgtcgtt
    22081 aaaacttggt ctacataggc ataatttgct gctaggacaa tggctttctt ttcactttcc
    22141 tcttgtctcg atagctgatt taaaagcctt tgtttcattt caaactcttt atatgttgct
    22201 gtgtcagata aaccgctagc ttgaccgttg gagagactga attccaacat ttgacgataa
    22261 atcgccaaat gcttttctaa agggtaaccc atattagcta gtagcgtaat gcgttcggac
    22321 atggcatcaa ccaatgcatg catccacttt tctgtccaaa ttcttgatag actacctttt
    22381 ctaatacgat aagcataaag acttttattt aaataaatta ccttttctga taataaatat
    22441 accttttgat tgaggtaacc atcttctcct aatttaccca tgtcaaagcg caactgctca
    22501 aacaatctcg ccttatagag tttaccccaa gcagatatca aagcgaaact cctcatttct
    22561 tgagtttcat acaaattctc aaagatggaa acattgtcat ataccttctc ataataggag
    22621 tctcctgata tatgaaagta gaacattcct tcactttcgt tgaaagaata gtaattccca
    22681 actgcaatat cagcttgata ttctgttatt tctttatata gggtttctac ataatctaac
    22741 tcaatccaat catccgagtc cacaaaggtc acataatttc cggacatatt attcagaccg
    22801 gtgtttcgtg cggcagaaag accagcattt tcttgttcta tatagagaat tcggtgatcc
    22861 atttctgaaa attctttaca aatttcacct gaagcatccg tagaaccatc attaacgaca
    22921 acaatctcaa tatttttata tgtttgagta ataatactat ctaggcactt cctcagatag
    22981 ttttccacat tgtatactgg tacaatgacc gttattttat catccactag caattttctc
    23041 cttgatttat gtgcgcgagt tagtttagcc taactttaca ggttgtctta ctcttcttca
    23101 tcacgtttac ggcgtttcgc aaccaatcca atacctgtaa cagctgctag aactccaagt
    23161 aacacagatc caattgacga ctcagtacct gtattaggca attctttttg ggatttacct
    23221 gtcgatccag aagtatttcc aacttgtgag ttcgaatggt ttgctgaatt tgaaactgat
    23281 gtacttgctg aagctgaggc gcttgtgctt gctaaagctg aggctgaggc acttgttgat
    23341 gcggattcag atgctgatgt gcttgcagat actgaagccg aagcactcgt tgacgctgaa
    23401 gctgaagcac ttgttgaggc tgatgctgag gcgctagtac ttgctgaggc tgaagcactt
    23461 gttgatgctg aagctgacgc actcgttgag gctgaggctg aagcacttgt tgatgcggat
    23521 gctgacgcac tggttgatgc cgattcagag gcactggttg atgcggattc agacgcactt
    23581 gtgcttgctg aggccgaggc actggttgat gcggattcag aggcactggt acttgctgac
    23641 tctgatgcac ttgtacttgc tgaggctgag gcgctggttg acgctgaagc cgacgcactc
    23701 gttgatgcgg aagctgacgc actggtgctt gctgaagctg acgcactggt tgacgctgat
    23761 tcagatgctg aggtgcttgc tgaagctgac gcactggttg acgctgagac tgaagcactc
    23821 gttgaggccg attcagacgc tgaggtgctt gctgaagctg atgcactggt acttgctgag
    23881 gccgaggcac tcgttgatgc tgaagctg
//
LOCUS       DAVHTH010000032        23630 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.032, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000032 DAVHTH010000000
VERSION     DAVHTH010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23630)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23630)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23630
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.032"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            <1..292
                     /locus_tag="VVR63_001304"
     CDS             <1..292
                     /locus_tag="VVR63_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HEU6129321.1"
                     /translation="RNIGQAGKILADSGYQGLMKIYPQAQTPRKSSKFKPLTVEDKTY
                     NHALSKERSKVENIFAKVETFKMFSTTYRNHRKRFGLRMNLIAGIINHELGF"
     gene            complement(281..928)
                     /locus_tag="VVR63_001305"
                     /pseudo
     CDS             complement(281..928)
                     /locus_tag="VVR63_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345255.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
     gene            complement(1037..1555)
                     /locus_tag="VVR63_001306"
     CDS             complement(1037..1555)
                     /locus_tag="VVR63_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HEU6129322.1"
                     /translation="MRTYENKEELKAEIEKTFEKYILEFDNIPENLKDKRADEVDRTP
                     AENLAYQVGWTNLVLKWEEDERKGLQVKTPSDKFKWNQLGELYQWFTDTYAHLSLQEL
                     KAKLNENIHSISAMIDSLSEEELFEPHMRKWADEATKTATWEVYKFIHVNTVAPFGTF
                     RTKIRKWKKIVL"
     gene            complement(1782..2651)
                     /gene="rsmI"
                     /locus_tag="VVR63_001307"
     CDS             complement(1782..2651)
                     /gene="rsmI"
                     /locus_tag="VVR63_001307"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HEU6129323.1"
                     /translation="MQIQKSFKGQSPYGKLYLVATPIGNLDDMTFRAIQTLKEVDWIA
                     AEDTRNTGLLLKHFDISTKQISFHEHNAKEKIPDLIGFLKAGQSIAQVSDAGLPSISD
                     PGHDLVKAAIEEEIAVVTVPGASAGISALIASGLAPQPHIFYGFLPRKSGQQKQFFDS
                     KKDYPETQIFYESPHRVADTLENMLEVYGDRSVVLVRELTKIYEEYQRGTISELLESI
                     AETSLKGECLLIVEGASQDVEEKGEEDLFLEIQARIQQGMKKNQAIKEVAKIYQWNKS
                     QLYAAYHDWEEKQ"
     gene            complement(2654..2971)
                     /gene="yabA"
                     /locus_tag="VVR63_001308"
     CDS             complement(2654..2971)
                     /gene="yabA"
                     /locus_tag="VVR63_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HEU6129324.1"
                     /translation="MDKKELFDALDDFSQQLLVTLADVEAIKKNLKSLVEENTALRLE
                     NSKLRERLGEVEADAPVKAKHVRESVRRIYRDGFHVCNDFYGQRREQDEECMFCDELL
                     YRE"
     gene            complement(3011..3901)
                     /locus_tag="VVR63_001309"
     CDS             complement(3011..3901)
                     /locus_tag="VVR63_001309"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HEU6129325.1"
                     /translation="MKQDQLKAWQPAQFDRFVRILEQDQLNHAYLFSGFFGSLEMAQF
                     LAKSLFCTDKVGVLPCEKCRSCKLIEQEEFPDVTLIKPVNQVIKTERIRELVGQFSQA
                     GIESQQQVFIIEQADKMHPNAANSLLKVIEEPQSEVYIFFLTSDEEKMLPTIRSRTQI
                     FHFKKQEEKLILLLEQMGLVKKKATLLAKFSQSRAEAEKLANQASFWTLVDESERLLT
                     WLVAKKKESYLQVAKLANLADDKEKQDQVLRILEVLCGQDLLQVRVRVILQDLLEARK
                     MWQANVSFQNAMEYLVLKEI"
     gene            complement(3898..4536)
                     /locus_tag="VVR63_001310"
     CDS             complement(3898..4536)
                     /locus_tag="VVR63_001310"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HEU6129326.1"
                     /translation="MSKGFLVSLEGPEGAGKTSVLEALLPILKEKGVEVLTTREPGGV
                     LIGEKIREVILDPSHTQMDAKTELLLYIASRRQHLVEKVLPALEAGKLVIMDRFIDSS
                     VAYQGFGRGLDIEAIDWLNQFATDGLKPDLTLYFDIEVEEGLARIAANSDREVNRLDL
                     EGLDLHKKVRQGYLSLLDKEGNRIVKIDASLPLEQVVETTKAVLFDGMGLAK"
     gene            complement(4756..5553)
                     /gene="proC"
                     /locus_tag="VVR63_001311"
     CDS             complement(4756..5553)
                     /gene="proC"
                     /locus_tag="VVR63_001311"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HEU6129327.1"
                     /translation="MKIGFIGLGNMGASLAKSVLQTRTSDEILLANRSQAKVDAFIAD
                     FGGQASSNEEMFAEADVIFLGVKPAQFSELLSQYQTILEKRESLLLISMAAGLTLEKL
                     ASLIPSQHRIIRMMPNTPASIGQGVISYALSPNCRAEDSEIFCQLLAKAGLLVELGES
                     LINAATGLAGCGPAFVYLFIEALADAGVQTGLPRETALKMAAQTVVGAGQLVLESQQH
                     PGVLKDQVCSPGGSTIAGVASLEAHAFRGTVMEAVHQAYKRTQELGK"
     gene            complement(5557..6819)
                     /locus_tag="VVR63_001312"
     CDS             complement(5557..6819)
                     /locus_tag="VVR63_001312"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HEU6129328.1"
                     /translation="MVSRQEQFEQVQAVKKSINTASEEVKNQALLAMADHLVAATEEI
                     LAANALDMAAAKGKISDVMLDRLYLDADRIEAMARGIREVVALPDPIGEVLETSQLEN
                     GLVITKKRVAMGVIGIIYESRPNVTSDAAALTLKSGNAVVLRSGKDAYQTTHAIVTAL
                     KKGLETTTIHPNVIQLVEDTSRESSYAMMKAKGYLDLLIPRGGAGLINAVVENAIVPV
                     IETGTGIVHVYVDKDADEDKALSIINNAKTSRPSVCNAMEVLLVHENKAASILPRLDQ
                     MLVADRKEAGLEPIQFRLDSKASQFVSGQAAQAQDFDTEFLDYILAVKVVSSLEEAVA
                     HIESHSTHHSDAIVTENAEAAAYFTDQVDSAAVYVNASTRFTDGGQFGLGCEMGISTQ
                     KLHARGPMGLKELTSYKYVVAGDGQIRE"
     gene            complement(6829..7959)
                     /locus_tag="VVR63_001313"
     CDS             complement(6829..7959)
                     /locus_tag="VVR63_001313"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004240022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HEU6129329.1"
                     /translation="MNNRSETMKYKRIVFKVGTSSLTNEDGSLSRSKVKDITQQLAML
                     HEAGHELILVSSGAIAAGFGALGFKKRPTKIADKQASAAVGQGLLLEEYTTNLLLRQI
                     VSAQILLTQDDFVDKRRYKNAHQALSVLLNRGAIPIINENDSVVIDELKVGDNDTLSA
                     QVAAMVQADLLVFLTDVDGLYTGNPNSDPRAKRLERIETINCEIIDMAGGAGSSNGTG
                     GMLTKIKAATIATESGVPVYICSSLKSDSMIEAAEETEDGSYFVAQEKGLRTQKQWLA
                     FYAQSQGSIWVDKGAAEALSQHGKSLLLSGIVEAEGVFSYGDIVTVFDKESGKSLGKG
                     RVQFGASALEDMLRSQKAKGVLIYRDDWISITPEIQLLFTEF"
     gene            complement(8039..9922)
                     /gene="cbpE"
                     /locus_tag="VVR63_001314"
                     /gene_synonym="pce"
     CDS             complement(8039..9922)
                     /gene="cbpE"
                     /locus_tag="VVR63_001314"
                     /gene_synonym="pce"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine esterase CbpE"
                     /protein_id="HEU6129330.1"
                     /translation="MKKKLTSLALVGAFLGLSWYGNVQAQESSGNKIHFINVQEGGSD
                     AIILESNGHFAMVDTGEDYDFPDGSDSRYPWREGIETSYKHVLTDRVFRRLKELGVQK
                     LDFILVTHTHSDHIGNVDELLSTYPVDRVYLKKYSDSRITNSERLWDNLYGYDKVLQT
                     AAEKGVSVIQNITQGDAHFQFGDMDIQLYNYENETDSSGELKKIWDDNSNSLISVVKV
                     NGKKIYLGGDLDNVHGAEDKYGPLIGKVDLMKFNHHHDTNKSNTKDFIKNLSPSLIVQ
                     TSDSLPWKNGVDSEYVNWLKERGIERINAASKDYDATVFDIRQDGLVNISTSYKPIPS
                     FQAGWHKSSYGNWWYQAPDSTGEYAVGWNEIKGEWYYFNQTGILLQNQWKKWNNRWFY
                     LTDSGVAAKNWKKIAGIWYYFNKENQMEIGWIQDKEQWYYLDVDGSMKTGWLQYKGQW
                     YYFAPSGEMKTGWVKDKEAWYYMDSTGIMKTGEIEVAGHHYYLEESGAMKQGWLKKAN
                     DWYFYKTDGSRAIGWIKDKDKWYFLKENGQLLVNGKTPEGYTVDSSGAWLVDVPIEKS
                     ATIKTTSHSEIKESKEVVKKDLENKETSQHESVTNSSTSQDLTSSTSQSSETSVNKSE
                     SEQ"
     gene            complement(9925..10812)
                     /locus_tag="VVR63_001315"
     CDS             complement(9925..10812)
                     /locus_tag="VVR63_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEU6129331.1"
                     /translation="MEIKIETGGLRLDKALSDLSELSRSLANEQIKSGQVLVNGQVKK
                     AKYTVQEGDVVTYHVPEPEVLEYVAEDLPLEIVYQDEDVAVVNKPQGMVVHPSAGHTS
                     GTLVNALMYHIKDLSGINGVLRPGIVHRIDKDTSGLLMIAKNDDAHLVLAQELKDKKS
                     LRKYWAIVHGNLPNDRGVIEAPIGRSEKDRKKQAVTAKGKPAVTRFHVLERFGDYSLV
                     ELQLETGRTHQIRVHMAYIGHSVAGDEVYGPRKTLKGHGQFLHAKTLGFTHPRTGKTL
                     EFKADIPEIFKETLERLRK"
     gene            complement(10802..11263)
                     /locus_tag="VVR63_001316"
     CDS             complement(10802..11263)
                     /locus_tag="VVR63_001316"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HEU6129332.1"
                     /translation="MKKRAIVAVIVLLLIGLDQLVKSYIVQQIPLGEVRSWIPNFVSL
                     TYLQNRGAAFSILQDQQLLFAVITLVVVIGAIWYLHKHMEDSFWMVLGLTLIIAGGLG
                     NFIDRVSQGFVVDMFHLDFINFAIFNVADSYLTVGVIILLIAMLKEEINGN"
     gene            complement(11260..12168)
                     /locus_tag="VVR63_001317"
     CDS             complement(11260..12168)
                     /locus_tag="VVR63_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEU6129333.1"
                     /translation="MNIQQLRYVVAIANSGTFREAAEKMYVSQPSLSISVRDLEKELG
                     FKIFRRTSSGTFLTRRGMEFYEKAQELVKGFDIFQNQYANPEEEKDEFSVASQHYDFL
                     PPTITAFSERYPDYKNFRIFESTTVQILDEVAQGHSEIGIIYLNNQNKKGIMQRVEKL
                     GLEVIELIPFHTHIYLCEGHPLAQKEELVMEDLADLPTVRFTQEKDEYLYYSENFVDT
                     SASSQMFNVTDRATLNGILERTDAYATGSGFLDSDSVNGITVIRLKDNLDNRMVYVKR
                     EEVELSQAGTLFVEVMQEYFDQKRKS"
     gene            12161..12358
                     /locus_tag="VVR63_001318"
     CDS             12161..12358
                     /locus_tag="VVR63_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU6129334.1"
                     /translation="MFIFYPQLLYLFIIPYFRSFPKRKKEHPILLNYLHYLPFSRQSY
                     FQNQFKKISGYTPLQYRKEKR"
     gene            complement(12410..13081)
                     /locus_tag="VVR63_001319"
     CDS             complement(12410..13081)
                     /locus_tag="VVR63_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU6129335.1"
                     /translation="MKKRAIQILLALSLIFYKSTWFWRVFNHLAKPYLPASREFFQIL
                     LLMESGVLFLAVIYLLVFAGKKIFHFKWQLRYFIYLLLGYIISYMSDFLFSYFISLSS
                     NQISLNETIEMMGRQEFPYFLLIVCFIAPIAEELIYRGVLMTTFFKNSPWYGDVLLSA
                     IIFGYIHINFALTPLAFFIYASGGLILALLYRMTKNLYYPILVHILINITAFWDVWLL
                     LFSGS"
     gene            complement(13135..13356)
                     /locus_tag="VVR63_001320"
     CDS             complement(13135..13356)
                     /locus_tag="VVR63_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000602450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0924 family bacteriocin-like peptide"
                     /protein_id="HEU6129336.1"
                     /translation="MILMTKNINLTNEELELIQGGADSYGKNPNGRYDWEIEPVLTLP
                     VHGFCSRGTYDLGYIGGGNHLCKGSAARF"
     gene            13628..14437
                     /locus_tag="VVR63_001321"
     CDS             13628..14437
                     /locus_tag="VVR63_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU6129337.1"
                     /translation="MIKLLALDMDGTLLNEAKEIPQAHITAIHKAIEKGVKLVLCTGR
                     PLFGVLPYYKKLELDLQNEYIIVNNGCSTHQTSDWSLVDWKELSPADIEYLYDLAEKS
                     DVQLTLFDESHYFVLGGKPNQVIENDAKLVFSDLTEISLEEATSGKFRMFQGMFLGTK
                     EQTDDFEQRFAEELCQRFSGVRSQPVIYEAMPLGTTKATALSRLAEILKIDSSEIMAM
                     GDANNDIEMLQFAGLGIAMGNASDYVKSLADAVTSSNEEDGVARAIEKYIL"
     gene            complement(14618..15493)
                     /gene="aguB"
                     /locus_tag="VVR63_001322"
     CDS             complement(14618..15493)
                     /gene="aguB"
                     /locus_tag="VVR63_001322"
                     /EC_number="3.5.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-carbamoylputrescine amidase"
                     /protein_id="HEU6129338.1"
                     /translation="MRNVRVATIQMQCAKDVATNIQTAERLVRQAAEQGAQIILLPEL
                     FEHPYFCQERQYDYYQYAQSVAENTAIQHFKVIAKELQVVLPISFYEKDGNVLYNSIA
                     VIDADGGVLGVYRKTHIPDDHYYQEKFYFTPGNTGFKVWNTRYAKIGIGICWDQWFPE
                     TARCLALNGAELLFYPTAIGSEPILDTDSCGHWQRTMQGHAAANIVPVIAANRYGLEE
                     VTPSEENGGQSSSLDFYGSSFMTDETGAILERAERQEEAVLLATYDLDKGASERLNWG
                     LFRDRRPEMYRQITD"
     gene            complement(15503..16588)
                     /gene="aguA"
                     /locus_tag="VVR63_001323"
     CDS             complement(15503..16588)
                     /gene="aguA"
                     /locus_tag="VVR63_001323"
                     /EC_number="3.5.3.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatine deiminase"
                     /protein_id="HEU6129339.1"
                     /translation="MMDSPKKLGYHMPAEYEPHHGTLMIWPTRPGSWPFQGKAAKRSF
                     TQIIETIAEGERVYLLVEQAYLSEAQSYLGDKVVYLDIPTNDAWARDTGPTILVNDKG
                     KKLAVDWAFNAWGGTYDGLYQDYEEDDQVASRFAEALGKPVYDAKPFVLEGGAIHSDG
                     QGTILVTESCLLSPGRNPNLTKEEIENTLLESLGAEKVIWLPYGIYQDETNEHVDNVV
                     AFVGPAEVVLAWTDDENDPQYAMSKADLELLEQETDAKGCHFTIHKLPIPAVRQVVTE
                     EDLPGYIYEEGEEERYAGERLAASYVNFYIANKAVLVPQFEDVNDQVALDILSKCFPD
                     RKVVGIPARDILLGGGNIHCITQQIPE"
     gene            complement(16585..17712)
                     /gene="nspC"
                     /locus_tag="VVR63_001324"
     CDS             complement(16585..17712)
                     /gene="nspC"
                     /locus_tag="VVR63_001324"
                     /EC_number="4.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxynorspermidine decarboxylase"
                     /protein_id="HEU6129340.1"
                     /translation="MKLEQVPTPAYVIDLAKLEANCRILQYVQEEAGCKVLLAQKAYS
                     LYKTYPLISQYLSGTTASGLYEAKLAREEFPGEVHVFAPAFKDADLEELLGITDHIVF
                     NSERQLRKHGARCREAGVSVGLRLNPQCSTQGDHALYDPCAPGSRFGVTIDKIPSDLL
                     DLVDGLHFHTLCEQGADDLQTTLKAVEEQFGPYLHEVKWLNMGGGHHITREGYDVDLL
                     ISEIKRIRKTYNLEIYIEPGEAIALNAGYLATEVLDIVENGMEILVLDASATCHMPDV
                     LEMPYRPPLRNGFEAQEKAHTYRLSSNTCLTGDVIGDYSFENPVQIGDRLYFQDMAIY
                     SFVKNNTFNGIGLPSLYLMDEQGDCSLLKAFGYQDFKGRLS"
     gene            complement(17712..18971)
                     /locus_tag="VVR63_001325"
     CDS             complement(17712..18971)
                     /locus_tag="VVR63_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase family protein"
                     /protein_id="HEU6129341.1"
                     /translation="MSRLLVIGCGGVAQVAISKICQDSETFTEIMIASRTKSKCDDLK
                     AKLEGKTSTKIETAALDADKVEEVIALIESYKPEAVLNVALPYQDLTIMDACLATGVH
                     YIDTANYEAEDTEDPEWRAIYEKRCKELGFTAYFDYSWQWAYQEKFKEAGLTALLGSG
                     FDPGVTSVFSAYALKHYFDEIHYIDILDCNGGDHGYPFATNFNPEINLREVSAPGSYW
                     EDGKWVEVEAMSIKREYDFPQVGQKDMYLLHHEEIESLAKNIPGVKRIRFFMTFGQSY
                     LTHMKCLENVGLLRTDTINFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGV
                     KDGVEKTIYIYNVCDHQECYAEVGSQAISYTTGVPAMIGTKLVMNGTWKQAGVYNLEE
                     LDPDPFMEALNEYGLPWVVVENPQMVD"
     gene            complement(18968..19828)
                     /gene="speE"
                     /locus_tag="VVR63_001326"
     CDS             complement(18968..19828)
                     /gene="speE"
                     /locus_tag="VVR63_001326"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HEU6129342.1"
                     /translation="MDLWFSEVHTPDVKLSLRTAKQLYAGKSEWQDIEVLDTPAFGKI
                     LILNGHVLFSDADDFVYNEMTVHVPMAVHPNPKKVLVIGGGDGGVAQVLTLYPELEQI
                     DIVEPDEMLVEVCREYFPDFAAGLDDPRVTIYYQNGLRFLRNCEDDYDIIINDATDPF
                     GHTEGLFTKEFYGNSYRALKEDGIMIYQHGSPFFDEDESACRSMHRKVNQAFPISRVY
                     QAHIPTSPAGYWLFGFASKKYHPVKDFDKEGWKKRQLFTEYYTANLHVGSFMLPKYVE
                     DILEEEEGKK"
     gene            20084..20799
                     /locus_tag="VVR63_001327"
                     /pseudo
     CDS             20084..20799
                     /locus_tag="VVR63_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809094.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            complement(20765..22240)
                     /locus_tag="VVR63_001328"
     CDS             complement(20765..22240)
                     /locus_tag="VVR63_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HEU6129343.1"
                     /translation="MKELDQNQAPIYEALVKLRKKRIVPFDVPGHKRGRGNPELVELL
                     GEKCVGIDVNSMKPLDNLGHPISIIRDAEELAADAFGASHAFLMIGGTTSSVQTMILA
                     TCKAGDKIILPRNVHKSAINALVLCGAIPIYIEMSVDPKIGIALGLENDRVAQAIKDH
                     PDAKAILINNPTYYGICSDLKGLTEMAHEAGMMVLVDEAHGAHLHFTGKLPISAMDAG
                     ADMAAVSMHKSGGSLTQSSLLLIGEQMNSEYVRQIINLTQSTSASYLLMASLDISRRN
                     LALRGKESFEKVIELSEYARREINAIGGYYAYSKELIDGVSVCDFDVTKLSVYTQGIG
                     LTGIEVYDLLRDEYDIQIEFGDIGNILAYISIGDRIQDIERLVGALADIKRLYSRDGK
                     DLIAGEYIQPELVLSPQEAFYSERKSLTLDESVGQVCGEFVMCYPPGIPILAPGERIT
                     REIVDYIQFAKERGCSLQGTEDSEVNHINVIKRKTNYKKSQ"
     gene            22947..>23630
                     /locus_tag="VVR63_001329"
     CDS             22947..>23630
                     /locus_tag="VVR63_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEU6129344.1"
                     /translation="MQDNYTTKAKHLTIDSRRLIERWKKEGKSNREIASLLGKAPQTI
                     HTEIKRRTVRQCLGKGRFKEVYSADYAQQSYENNRKHSVKRSSVTKELKEKILHYHNQ
                     KFSPEMMVMAKGVNVGISTIYYWIHHGKLGLSKQDLLYPRKGKALKKQASTNFKPAGQ
                     SIEQRPEAINLRLENGHYEIDTVLLTRSKNYCLLVLTDRKSRHQIIRLIPNKSAEVVN
                     QALKLILKQH"
BASE COUNT         6956 a         5383 c         4218 g         7073 t
ORIGIN      
        1 cagaaatatc ggacaagctg gtaaaatctt ggctgacagt ggttatcaag ggctcatgaa
       61 gatatatcct caagcacaaa ctccacgtaa atccagcaaa ttcaagccgc taacagttga
      121 agataaaacc tataaccatg cgctatctaa ggagagaagc aaggttgaga acatctttgc
      181 caaagtagaa acgtttaaaa tgttttcaac aacctatcga aatcatcgta aacgattcgg
      241 attacgaatg aatttgattg ctggtattat caatcatgaa ctaggattct agttttgcag
      301 gaagtctaat gtaattctca agctgtgagt tcattatgat ttgtaaatcc tatatatctt
      361 cagcagctaa aaacacattt tgaaatgttc caagtccgtt ttcaccaaaa ctatattctc
      421 tcttactata cttactctta ttattctcta tatagttaga gtcaaggttc ttaacctctt
      481 gaagttcatt ttctttactt ctgaggttaa aatcttttac ttctgaagtt aagttttttg
      541 acttctgtaa gtcattttct tttacctgaa atatactcat aaagtcttta acataaatga
      601 tgttcggctt accaagtcca agccttactc tttcgatcag tcctattcct ttttttatat
      661 caagctcatc taatgttttt atggcagttg gctttgagat atttcttctt ttcataattt
      721 cttcgacagt aaaatagata aatactctgc cttccttgtc tatccagtta ttcttaaatg
      781 acattcctgt ctatttaaga agtatggaat aaaggataat tgcttctgct gataagcccc
      841 gaaattcttc tctatcaact aatatctccg gtacttttaa gaagttaaat cttttcgctt
      901 ctctgttata aaaatattca aagtccatgc aagatcacct cccttcttaa aaatttgcaa
      961 agaaaaagac gatagttttt cttctatcgc ctttggtaac catttttatg aaatttttta
     1021 aagttaaaaa tataatttat aatactatct tcttccattt tctgatttta gttctgaaag
     1081 ttccaaaagg tgcaaccgta tttacatgaa taaacttata cacttcccaa gtcgctgttt
     1141 tagtcgcttc atcagcccac tttctcatat gcggttcaaa taattcttcc tcactcaacg
     1201 aatcaatcat tgcagagata gaatgaatat tttcatttaa ttttgctttc aactcttgca
     1261 gagataaatg agcgtaggta tctgtgaacc actgatataa ttcaccaagt tgattccatt
     1321 taaatttatc cgatggtgtt tttacttgaa gcccctttct ttcatcttct tcccatttaa
     1381 gaaccaagtt ggtccaacca acctgataag caaggttttc tgctggagtt ctgtcaactt
     1441 catcagctct cttatctttt aaattttctg gaatattatc aaattctaaa atatatttct
     1501 caaatgtttt ctctatctca gcttttagtt cttctttatt ttcgtatgtt cgcaaaaaat
     1561 caccttcttt ctgatttatc aatcctttga tttaaaatga ccttattttt ctatttatac
     1621 cttctaagaa cgctataact gctgctccaa ccatcggtat tccgtatggg cttaataaaa
     1681 aacttaatac caaagcttct ataccaagtg atacatcttt atattatcat cactaattaa
     1741 gttaaacaga aacagacaga attattacat cctgtctccc tttattgttt ttcttcccag
     1801 tcgtggtagg cagcgtagag ttgactctta ttccactggt aaatcttagc tacttcctta
     1861 atagcttgat ttttcttcat accttgctga atacgagctt ggatttctaa gaacaagtct
     1921 tcctcgcctt tttcttccac atcctgactg gcaccttcaa caatcagaag acattcaccc
     1981 ttgagagacg tttcagcaat gctttccagc aattcagaaa ttgtacctct ttggtattct
     2041 tcatagattt tggtcaattc cctgaccaag acaacggagc ggtcaccgta gacttctagc
     2101 atattttcca atgtatctgc cacacgatgg ggcgattcat aaaaaatctg agtttcagga
     2161 tagtcttttt tcgagtcgaa aaattgcttt tgctggcctg attttctcgg taaaaagccg
     2221 taaaagatat gtggctgcgg cgctaaacca ctggcaatca aggcggaaat tcctgcagag
     2281 gcacctggaa ctgtaacaac tgcaatttct tcctcaatag ctgccttaac caaatcatga
     2341 ccagggtctg aaatgctagg caaaccggca tcagagacct gagcaatact ttgccctgct
     2401 ttcaagaaac caatcaaatc aggaattttt tccttggcat tgtgctcatg aaaactgatc
     2461 tgcttggtgg aaatgtcaaa atgcttgagc aaaagccctg tattgcgcgt atcctcagca
     2521 gcaatccagt ccacttcttt caaggtctgg atagcacgaa aagtcatatc atctagattg
     2581 ccaatcggcg ttgccactag atacagcttg ccatagggag actgcccctt aaaacttttt
     2641 tgaatttgca tgcttactcc ctgtataaca actcatcaca gaacatacat tcttcgtcct
     2701 gctctcgacg ttgtccataa aaatcattac atacgtgaaa tccatcacgg taaatacgac
     2761 ggacactttc gcgaacatgc ttggccttga cgggagcgtc tgcttccacc tcacccaagc
     2821 gttctcgcaa cttactattt tccaagcgaa gagctgtatt ttcttctacc aagctcttga
     2881 gatttttctt gatggcttcc acatcggcta aggttaccaa taattgttgg gaaaaatcat
     2941 ccagcgcgtc aaataattct tttttgtcca taaaacagcc ctttcctttc tttatcattc
     3001 atttttgagt ttatatttct ttcaagacca gatattccat ggcattttga aagctgacat
     3061 tagcttgcca catttttcta gcttctagta aatcttgtag aatcactctt actcttacct
     3121 gcaagaggtc ctgcccacag agaacttcaa gaatccgtaa aacctgatcc tgtttttcct
     3181 tatcatctgc caagttggct aatttggcaa cctgtagata actttctttt ttcttagcta
     3241 ctaaccaagt cagcaggcgt tcactttcat cgaccaaggt ccaaaaactt gcctgattag
     3301 ccaacttttc tgcttcagct cgcgattgac taaacttagc taaaagagtc gcttttttct
     3361 taacaagtcc catttgttct aagagtaaga taagtttttc ttcttgcttt ttaaagtgga
     3421 agatctgagt ccgacttcgg attgtcggta acatcttttc ctcatcgcta gtcaagaaga
     3481 aaatataaac ttcactctgg ggttcttcga tgaccttgag cagagaattg gctgcgttgg
     3541 gatgcatttt atccgcttgc tcgataataa agacctgttg ctggctttca atccctgctt
     3601 gagaaaactg tcccaccaat tcccgaatgc gttctgtctt gatgacctga ttgactggct
     3661 taatcaaggt gacatctgga aactcttcct gttcaatcag cttgcaactt cggcatttct
     3721 cacatggtaa gacgccaact ttatccgtac aaaagaggct cttagctaaa aattgcgcca
     3781 tttccaagct tccaaagaaa cctgaaaaga gataggcgtg attgagctgg tcttgttcta
     3841 agatacggac aaaacggtca aactgagctg gttgccaagc ctttagttga tcttgtttca
     3901 tttggccaag cccattccgt caaacaagac agccttggta gtttccacaa cttgctccaa
     3961 agggagacta gcatcaatct tgacaatgcg atttccctct ttatccagaa gagaaaggta
     4021 gccttgacga acttttttat gcaagtccaa cccttccaaa tccaaacgat taacctcgcg
     4081 gtcactattc gcagcaatac gagccagccc ttcttccacc tcgatgtcaa aatagagtgt
     4141 caaatcgggt ttgaggccat ctgtcgcaaa ctgattgagc cagtcaatgg cttcaatatc
     4201 taagccacga ccaaatccct gataggcaac agaactatcg ataaaacgat ccatgatgac
     4261 caacttgcca gcttcaaggg ctggaagaac tttttccacc aaatgctgtc tgcgactggc
     4321 aatatagaga agtagctctg ttttagcatc catctgagta tgacttggat ccaaaatcac
     4381 ttcccgaatc ttctccccaa tcaagactcc gccaggttca cgggtcgtca acacctctac
     4441 tcctttttcc tttaaaattg gtagcagagc ctctaaaaca ctggtcttgc ctgctccctc
     4501 tggtccctca agagagacta aaaatccttt tgacatgtct aactcatttc ttttttacta
     4561 cttctattct atcaaaaaaa taggggtttg tgacaatctt tttgtcttct catttcatac
     4621 tcaatgaaaa tcaaagagca aactaggaag ctagccgcag gctgtacttg agtacggcaa
     4681 ggtgaagctg acgcagtttg aatttgattt tcgaagagta tcaaccacca taaaagaggc
     4741 agataaaact acctcttatt tacctagttc ttgtgttcgt ttataggctt gatgaactgc
     4801 ctccatgact gtgcctcgaa aagcatgcgc ttctaggctt gctacgccag caatagtcga
     4861 accgcctgga ctacaaactt gatctttcaa aactccagga tgttgctggc tttctaggac
     4921 caattgccca gctcctacca cagtttgggc tgccattttc aaggctgttt ctcgtggtaa
     4981 tcccgtctga acacctgcat ctgccaaggc ctcaataaag agatagacaa aggctggtcc
     5041 acaacctgca agacctgtcg ctgcattgat taagctttct cctaattcaa ccaagagacc
     5101 agccttggct aaaagctgac aaaagatctc actgtcctca gccctgcaat taggagacaa
     5161 ggcataacta atcactcctt gcccgataga agcaggggta ttaggcatca tacgaataat
     5221 tcggtgttgg cttgggataa gacttgctag tttttctaag gtcaatccag ctgccatcga
     5281 aatcaaaaga agactttctc ttttttcaag gatggtctga tattgagaaa gcagttcaga
     5341 aaactgagca ggcttaactc ctagaaaaat cacatctgct tctgcaaaca tttcttcatt
     5401 gctggaagcc tgaccaccaa agtctgcaat gaaagcatct accttagctt gactacgatt
     5461 ggcaaggaga atctcatctg acgtcctagt ctgcaagaca gattttgcca agctagcacc
     5521 catattcccc aaaccgataa atccaatctt catctcttac tcccttatct gcccatcacc
     5581 agcaaccaca tacttgtagc tggtcaactc tttcaagccc attggaccac gcgcgtgcaa
     5641 tttctgagta gaaatcccca tttcacaacc aagaccaaat tgtcctccat ctgtgaaacg
     5701 agttgaggca ttaacataca ccgctgcaga gtccacttga tctgtaaagt atgctgcagc
     5761 ttcagcattt tccgtcacaa tagcatccga atgatgggta ctgtgggatt caatatgcgc
     5821 aaccgcttct tctaaactgc tcacaacctt aacagctaga atatagtcta aaaactcggt
     5881 atcaaagtct tgtgcttgag cagcttgacc tgaaacaaac tggcttgctt tgctatctag
     5941 gcggaattga attggttcca acccagcttc ttttcgatct gcaaccagca tttgatccaa
     6001 gcgaggaagg atgcttgctg ccttgttttc atgaaccagc agaacctcca tggcattaca
     6061 aacagaagga cgactggttt tagcattgtt gatgatagac agcgccttgt cttcgtctgc
     6121 atccttatcc acatagacat ggacaatccc agtccctgtc tcgataacag gtacaatcgc
     6181 attctcaacc actgcattga tcaagccagc tcctccacga ggaatgagaa ggtctagata
     6241 gcccttggcc ttcatcatag cataactact ttcacggcta gtatcctcca ccagttgaat
     6301 cacatttgga tgaatagtag tcgtctccaa gcccttcttc aaggctgtga caatggcatg
     6361 ggttgtttga taggcatcct taccactacg aagaacaacc gcatttccac tcttaagagt
     6421 caaagcagcc gcatcagacg tcacatttgg acggctttca tagataatac cgatgacacc
     6481 catagctaca cgtttttttg tgataaccaa accattttca agctgacttg tttctaaaac
     6541 ttcaccgatt ggatctggta aggcaaccac ttcacgaatt cctcttgcca tcgcttctat
     6601 acgatctgca tccaaataaa gacgatccaa catcacatct gagattttcc ccttagccgc
     6661 tgccatatcg agggcattag ccgctaaaat ttcctcagta gcagccacta agtgatcagc
     6721 catggctagc aaggcttggt ttttcacttc ttcactagct gtgttaatcg attttttaac
     6781 agcctgtacc tgttcaaatt gttcttgtct actcaccata gtttacctct aaaattctgt
     6841 aaaaagtagt tggatttcag gagtaatgga aatccagtcg tcacggtaaa tcaagacacc
     6901 cttggctttt tgagaacgca acatatcctc caaagcagat gctccaaatt gcacgcgtcc
     6961 ttttccaagt gattttccac tttccttatc aaatactgtc acgatatcac cgtaagaaaa
     7021 gactccttct gcttcaacga taccagataa gagaagactc tttccatgtt gagagagagc
     7081 ttccgcagcc cctttatcaa cccaaataga accttgactc tgagcataga aggcaagcca
     7141 ttgtttctgg gtacgaagcc ccttctcttg agcaacaaag taagaaccat cctcggtctc
     7201 ctctgccgcc tcaatcatgg aatctgattt caaggatgag cagatataaa caggaactcc
     7261 tgattccgtc gcgatagttg cagccttgat tttggttaac atacccccag ttccgtttga
     7321 cgaaccagct ccaccagcca tatcaataat ctcacaattg atggtctcga ttctctccaa
     7381 gcgtttggct cttggatctg aattaggatt tccagtatag agaccgtcca catctgtcaa
     7441 gaaaactaaa aggtctgctt ggaccatcgc cgctacttga gcacttagag tgtcattgtc
     7501 cccaaccttg agctcatcaa taacgacact atcattctca ttgatgatag gaattgcccc
     7561 acggttgagc aaaaccgaca aagcctgatg ggcattttta taacgacgct tatccacaaa
     7621 gtcatcttgg gtcagcaaga tttgtgcaga aacgatttga cgcaagagaa gattggtcgt
     7681 atattcttcc aacaaaagtc cctgccctac cgctgctgaa gcctgtttat cagcaatttt
     7741 agtcggacgc tttttaaatc ctaaggctcc aaaaccagcc gcaatggcac ctgaagacac
     7801 caaaatcaac tcatgaccag cctcgtgcag catagccaac tgctgggtaa tatcctttac
     7861 cttactacgt gataaacttc catcctcatt tgtcagagaa gaagtaccca ccttaaagac
     7921 aatccgtttg tatttcatag tctcactccg attattcata tttatccatt ataacatgaa
     7981 taacaggaaa tagaaaagag ttgataggaa aaagaaggcc ctaaaacctt cttttctact
     8041 actgttctga ttccgatttg tttacactcg tttcagagct ttgtgaagtt gaggatgtca
     8101 aatcttgact agttgaagaa tttgtaacac tttcatgttg actcgtttct ttattttcaa
     8161 gatccttttt cactacttct ttggattctt ttatttctga atgacttgta gttttaattg
     8221 tagcagattt ctcgatcgga acatccacta accaggcacc acttgaatcc acagtatagc
     8281 cttctggtgt cttaccattc acaagtaatt gaccattttc tttcaagaag taccatttat
     8341 ccttgtcttt aatccaacct atagctcgtg aaccatctgt cttgtagaaa taccaatcat
     8401 ttgccttttt aagccagcct tgcttcatag ctcctgattc ttctagatag taatgatgtc
     8461 cagcaacttc tatctcacct gtcttcatga taccagtaga atccatatag taccaggctt
     8521 ctttatcttt tacccagccc gttttcattt cccctgatgg agcaaagtaa taccattgcc
     8581 ccttatattg aagccaacct gtcttcatag agccatcaac atccaaataa taccactgct
     8641 ctttatcttg aatccaacca atttccatct ggttttcttt gttaaaataa taccagattc
     8701 cagcgatttt cttccaattt ttagcagcaa caccagagtc tgtcaaatag aaccaacgat
     8761 tgttccattt tttccattga ttctgtaata agatacccgt ttggttaaag taataccatt
     8821 cacccttaat ttcattccaa ccgacagcat attctcctgt agaatcaggc gcttgatacc
     8881 accagtttcc atatgaactc ttatgccaac cagcttgaaa acttggaatc ggcttgtagg
     8941 aagttgaaat gtttactaaa ccgtcttgtc gaatatcaaa aactgttgca tcatagtctt
     9001 tgctggctgc attgattctc tcaattcctc gttctttgag ccaattaaca tactcactat
     9061 caacaccatt tttccaaggt agactatccg aagtttgaac aatcaaactc ggactcaaat
     9121 ttttaatgaa atccttggta tttgatttgt tggtatcatg gtgatgatta aacttcatca
     9181 aatcaacttt tccaatgaga ggaccatact tgtcttctgc tccatgaaca ttatctaaat
     9241 cgcccccaag gtaaattttc ttgccattga ctttcaccac gctaatcaag gaattggaat
     9301 tgtcatccca aattttcttt aattcacccg atgaatcagt ttcattttca taattataga
     9361 gctgaatatc catgtcccca aactgaaaat gagcatcccc ttgtgtgata ttttgaataa
     9421 ctgaaacacc tttttctgca gcagtctgta aaaccttatc atagccatac agattatccc
     9481 atagacgttc agaattagta atacgactat cactatattt cttaagatag actcggtcaa
     9541 ctggataggt agacagtaat tcatcaacat ttccaatatg atcactgtgg gtatgggtca
     9601 ccaaaataaa atcaagtttt tggacaccca attccttcaa acgacgaaag acacggtctg
     9661 ttagaacatg cttataagac gtttcaattc cttctctcca tggatagcga gaatcacttc
     9721 catctgggaa atcataatct tctcctgtat ccaccatggc aaaatgtcca ttgctttcaa
     9781 gaataatcgc atcactgcca ccttcttgaa cattgataaa gtggatttta tttcctgaac
     9841 tttcttgagc ctgaacattc ccataccatg acaaacctaa aaaagcgcct acaagtgcta
     9901 aactagttaa tttctttttc attcttactt tctcaatctc tccaaggttt ccttaaaaat
     9961 ctctgggata tctgctttaa attccaaggt cttacctgtt ctcggatgag taaaacctaa
    10021 agtcttggca tgaagaaatt gtccatgtcc tttcaaagtc ttgcgaggac catagacctc
    10081 atcaccagcg actgaatggc cgatataagc catgtggaca cggatttgat gagtgcgccc
    10141 tgtctccagt tgcaactcta ctaagctata atcgccaaag cgttccaaga cgtgaaaacg
    10201 cgtcactgca ggcttccctt tagcagttac agcctgtttc ttacggtctt tttcactccg
    10261 gccaatcggc gcttcaatta caccacgatc attaggcaga tttccatgaa caatcgccca
    10321 atatttgcgg agagactttt tatctttgag ttcttgggca agtactagat gcgcatcatc
    10381 gtttttagca atcatgagaa gacctgacgt atccttatca atacggtgaa caatccctgg
    10441 acgcagaacc ccattgatac ccgacaagtc cttaatatga tacatgaggg catttactag
    10501 ggttccactg gtatgaccag cactcgggtg cacaaccatt ccctgaggtt tgttaacgac
    10561 agccacatcc tcatcttggt agactatttc tagcggaaga tcctcagcca catactctaa
    10621 tacctctggt tctggcacat ggtaagtgac gacatcaccc tcttggactg tgtatttagc
    10681 tttcttgact tgaccattga ccaagacctg gcctgattta atttgttcat tcgcgagact
    10741 acgtgataat tctgacaaat ctgacaaagc cttatccaaa cgcagaccac cagtttcaat
    10801 tttaatttcc atttatttcc tcttttagca ttgcaatcaa taaaataatc actccaaccg
    10861 tcagatagct atctgccaca ttgaaaattg caaagttgat aaagtcaagg tggaacatat
    10921 ccacaacaaa gccctgactg accctgtcaa taaagtttcc aagaccaccc gcgattatta
    10981 gagtcaaacc caagaccatc cagaatgagt cctccatgtg tttatgtaaa taccaaatgg
    11041 cacctatcac gacaaccaga gtaatgacag cgaataacaa ctgctgatct tgtaagatag
    11101 aaaaggctgc acctcgattt tgcaggtagg tcaagctaac gaaattgggg atccaggagc
    11161 gcacttcacc cagtggaatc tgctggacga tataagattt gaccaactga tccagcccaa
    11221 ttaaaagcag tacaatgact gccactattg ctcttttttt catgatttcc tcttttgatc
    11281 aaaatattct tgcatgactt ctacgaagag agtcccagct tgactaagct ccacttcttc
    11341 acgtttaaca tagaccatgc ggttatctag gttatccttg agacgaataa ctgtaatgcc
    11401 attaacactg tcactatcta aaaatccaga acctgtcgca taggcgtccg tccgctccaa
    11461 aataccattc aaggtggcac ggtctgtcac attaaacatc tgtgagctag cgctggtatc
    11521 gacaaagttc tctgaataat aaaggtactc gtctttctct tgagtgaaac gaaccgttgg
    11581 taaatccgct aaatcctcca tgactaattc ctctttctgg gctaaaggat gaccctcaca
    11641 gagataaata tgggtatgga aaggaatcaa ttcgatgacc tccagaccta acttttcaac
    11701 ccgttgcata atcccctttt tattttgatt gttgaggtag ataatcccaa tctcactatg
    11761 cccttgcgcc acttcatcta atatttgaac agtagttgat tcaaaaatac ggaagttctt
    11821 atagtcagga tagcgctctg aaaaggccgt aatagttggt ggtaagaagt catagtgctg
    11881 gctagcaacg gaaaattcat ctttttcttc ttcaggattg gcatactgat tttgaaaaat
    11941 atcaaatcct ttaaccaatt cttgcgcttt ttcataaaat tccatcccac gacgggtcaa
    12001 gaaagtccct gagctggtcc gacggaaaat cttaaagccc aactcttttt ccaaatcacg
    12061 aacagaaata gacagactcg gctgactaac atacatcttt tcagcagctt cacgaaaagt
    12121 accactattg gcaatagcca caacatagcg taattgttga atgttcatct tctaccccca
    12181 acttctttat cttttcatta taccatattt tagaagtttt ccaaaaagga aaaaagaaca
    12241 tcctattctt cttaactatc ttcactatct gcctttctca cgccaatctt attttcaaaa
    12301 tcaattcaaa aaaataagtg gctacacacc acttcagtat cggaaagaaa aacgttgact
    12361 atttgtgaaa aaagaaaatg ccggaaaatt ccgacatttt tttagtaagc taacttcctg
    12421 aaaataggag taaccaaaca tcccagaagg cagtgatatt gatgagaata tgaactagta
    12481 ttggatagta gagattttta gtcatgcgat acaatagagc taaaatcaga cctccactag
    12541 cataaatgaa aaaagcaaga ggagttaaag caaaattgat atgaatataa ccgaaaataa
    12601 tagcagaaag caaaacatct ccgtaccaag gtgagttttt gaaaaaggtt gtcataagca
    12661 cacctcgata aatcaattcc tcagcaatag gggcgatgaa gcaaacgatg agcaagaaat
    12721 aagggaactc ctgtctcccc atcatttcta tcgtttcatt caaagaaatc tgatttgaag
    12781 acagggatat gaaatacgaa aagaggaagt cagacatata tgaaatgatg tagcccagta
    12841 aaaggtagat gaagtacctc agctgccact tgaaatgaaa aattttcttt cctgcaaaaa
    12901 ccagtagata gatgaccgct aagaaaagaa ctccgctctc catcaaaagc agaatctgaa
    12961 aaaattcacg acttgctggt agatagggct ttgcgaggtg attgaaaact ctccaaaacc
    13021 aagttgattt gtaaaaaatt aaggacaatg ctagtaaaat ttgaatagcc cgttttttca
    13081 tattaaattc tctgctttct ccacttgttt cttcatatta ctaataaatt ttacttaaaa
    13141 tctcgcagca cttcctttgc aaagatgatt gcctcctcca atatatccta aatcataggt
    13201 gcctctggaa caaaatccat gaaccggcag agttaatact ggttctattt cccaatcgta
    13261 cctaccatta ggatttttac catatgaatc tgctccacct tgtatcagct ctaattcttc
    13321 atttgttaga tttatatttt ttgtcattaa aatcatgata tatttcctcc attattcttc
    13381 agattagttg agtaatctga tactcatacc tacttacaaa aaaactatta tattaagttg
    13441 gttttttaat ttgtctagtt gcaacattga caaacatagt atagcatatc tttgccaaat
    13501 atcctcttca aatcatgaat tgtcatcaaa acatcttaaa ctataaaatc aattagtctc
    13561 aagctttcta tcaatttctt ctccaaaata tgctataata atagcaaaag ataaagaagg
    13621 aagacctatg attaaactac tagccttgga tatggacggc accctcctca atgaagccaa
    13681 ggaaatccca caagctcaca ttactgctat tcacaaagcc attgaaaaag gtgtcaaact
    13741 ggttctctgt acgggtcgcc cccttttcgg tgtcctcccc tactacaaaa aactggagct
    13801 tgacctccag aacgaatata ttattgttaa caacggttgt tcaactcacc agaccagtga
    13861 ttggagtcta gttgactgga aagaactgag tccagctgac atcgaatacc tctatgacct
    13921 tgctgaaaag agtgatgttc agttgacact ttttgacgag tcacattatt ttgttctcgg
    13981 tggcaaaccc aatcaagtta ttgaaaatga tgctaaacta gtattttcag acctgactga
    14041 aatttctctt gaagaagcga ctagtggaaa gttccggatg ttccaaggta tgtttttagg
    14101 aacaaaagaa caaacagacg attttgagca gcgttttgct gaagagcttt gccaacgatt
    14161 cagtggagtt cgttcgcagc ctgtcattta tgaagcaatg ccgcttggaa cgacaaaggc
    14221 tactgctctt tcacgactag ctgagatttt gaagattgat tcctcagaga ttatggccat
    14281 gggcgatgct aataacgata tcgaaatgct ccagtttgca gggcttggga ttgcaatggg
    14341 aaatgccagc gattatgtca aatctcttgc ggatgccgtt acctcaagca acgaagaaga
    14401 cggcgttgcg cgtgctattg agaaatatat tctataaaaa agaaaagcaa atagacagaa
    14461 gttactgcta tttgcttttt tgctaatatt ttaaaatacg gactaatcaa tagacaagaa
    14521 tagcgaatca taaaaatcga tttactagat gccatagtat cttatagttg ctaataagaa
    14581 gttagtctag cagaatgaat ctctcatttc tcccacacta atctgtaatt tgtctataca
    14641 tttctggtct tctatctcga aacaagcccc agtttagacg ttcacttgct cccttgtcta
    14701 ggtcataagt agctaacaga acagcttctt cttgtctttc agctcgttct agaatagctc
    14761 ctgtttcatc cgtcataaag gaggaaccgt agaagtcaag actggaactc tgtccgccat
    14821 tttcctcact aggagtaacc tcctctaaac cataacgatt ggctgcgatg actggaacaa
    14881 tattcgctgc tgcgtgccct tgcatagtac gttgccagtg accacaacta tctgtatcca
    14941 aaattggctc tgaaccgata gctgtaggat aaaagagcaa ttcagcacca ttcaatgcaa
    15001 gacagcgggc tgtttcaggg aaccattgat cccaacagat accgatacca atcttagcat
    15061 agcgagtatt ccagaccttg aaaccagtgt taccaggcgt gaaatagaat ttttcttgat
    15121 aataatggtc atctggtata tgggtctttc gataaacgcc cagcactccc ccatctgcat
    15181 caatgacggc aatagagtta tacaagacat taccatcttt ttcatagaaa ctgattggta
    15241 aaacaacttg tagttcctta gcaatcacct taaaatgctg aatggcagta ttttccgcta
    15301 cagattgggc atactggtag tagtcatact gacgttcctg acagaaatag ggatgttcaa
    15361 acaactcggg caagagaata atttgggctc cttgctcagc agcctgacgt actaaacgct
    15421 ctgcggtttg gatatttgtt gccacatcct tagcgcattg catctgaatg gttgcaactc
    15481 ttacatttct catctttttc tcctattctg gaatttgttg ggtgatacag tggatattgc
    15541 caccacctaa gagaatatct ctggctggta ttccgacaac tttacggtct gggaaacact
    15601 tgctgaggat atctaaggcc acttggtcgt ttacatcctc aaactgtgga accaagacag
    15661 ccttgttggc gatataaaag tttacgtagg aagctgctag tcgttcacct gcgtatcgct
    15721 cttcttctcc ttcttcatag atgtagcctg gcaaatcttc ttctgtcaca acttgtcgaa
    15781 ctgcagggat aggcaattta tgaatggtga agtgacaacc ttttgcatct gtttcctgtt
    15841 ctaagagttc gagatctgct tttgacatgg catactgggg atcattttcg tcatctgtcc
    15901 aagccaaaac aacctcagca ggaccaacaa aggcaacaac attatcgacg tgttcattgg
    15961 tttcatcctg ataaatacca taaggaagcc aaataacttt ttcagcacca agactttcta
    16021 ataatgtgtt ttcaatctcc tctttagtca ggttaggatt gcgaccagga ctaagcaagc
    16081 aactttcagt tacgagaata gttccttgac catcgctatg gattgcgcct ccttccagta
    16141 caaaaggttt agcatcatag acaggctttc ccaaggcctc agcaaaacga ctggctactt
    16201 ggtcatcctc ttcataatct tgataaagac catcataggt gcctccccaa gcattgaagg
    16261 cccaatccac ggctaatttc ttacctttat cattgacgag aatggttggg ccagtatcac
    16321 gcgcccaggc atcattggtg ggaatgtcta aataaacaac cttgtctcca agataggatt
    16381 gggcttcaga tagataggcc tgctccacca aaagatagac tctttcccct tctgctatgg
    16441 tctcgatgat ctgagtaaat gatcttttag cagcctttcc ttgaaaaggc catgatcctg
    16501 gtcgagtcgg ccatatcatg agggtaccat gatggggttc gtactctgct ggcatgtgat
    16561 agcctaattt ttttggactg tccatcatga taatctccct ttaaagtctt gatagccaaa
    16621 agctttgagt aagctacagt ctccctgttc gtccatgaga tagagacttg gcaatccaat
    16681 accattaaag gtattatttt tgacaaaaga ataaatggcc atgtcttgaa aataaagtct
    16741 gtctccgatt tggactggat tttcaaaact ataatcacca atcacatcgc ccgtcagaca
    16801 ggtattagaa gaaagtctgt aggtatgggc tttttcctgt gcctcaaagc catttctcaa
    16861 aggtggacga tagggcatct caagtacatc aggcatatgg caggtcgcag aggcgtctaa
    16921 aaccaagatt tccataccgt tttctacaat atctaatacc tcagttgcta aataacccgc
    16981 attaagcgca atggcttcac caggctcgat atagatttca agattgtaag tttttcggat
    17041 acgcttgatt tctgaaatca gcaaatccac atcgtaacct tctcttgtaa tatgatgacc
    17101 accacccata ttgagccatt ttacctcatg taagtaggga ccaaattgtt cttctactgc
    17161 tttcaaagtt gtttgtaaat catctgctcc ctgctcgcaa agggtatgaa aatgaagtcc
    17221 gtcaaccaaa tctagcaaat cactcggaat cttgtctata gtaactccaa agcgagaacc
    17281 tggtgcacaa gggtcataga gcgcgtgatc tccttgagtt gaacactgag ggttgaggcg
    17341 caaaccaaca ctgacaccag cctctcgaca acgagcccca tgcttacgca actgtctctc
    17401 tgagttaaag acgatatggt ctgttatccc aagcaattcc tccaagtctg catccttgaa
    17461 agcaggcgca aatacatgga cttcaccagg aaattcttcc cttgccaatt tggcctcata
    17521 gagtccacta gctgtcgtac ctgatagata ctggctaatc aagggataag ttttgtagag
    17581 ggaatatgcc ttctgggcaa gcaagacctt gcaaccggcc tcttcttgta catattgtag
    17641 aatgcggcaa ttagcttcta acttggccaa gtcaataaca taggctggtg ttggtacttg
    17701 ttctaacttc attagtccac catttgtgga ttttcaacca caacccatgg caaaccatac
    17761 tcattcaaag cttccatgaa tggatctgga tctaactcct caaggttata cactccagct
    17821 tgtttccaag ttccgttcat gactaatttt gtcccaatca tggctggaac gcctgtcgtg
    17881 tatgaaattg cttgtgaccc gacttctgca tagcactctt gatggtcgca aacattgtag
    17941 atgtagatag tcttttcaac gccatctttg acacctgtaa agatacatcc aatattggtt
    18001 tttccgactg tacgtgggcc aaggctagca ggatctggaa gcaaggcttt caaaaattga
    18061 attggaacaa tttcttggcc gttaaagtta atggtatccg tacgaaggag tccaacattt
    18121 tcaagacatt tcatgtgcgt caagtaagat tgaccaaaag tcataaagaa acgaatgcgt
    18181 ttgacacctg gaatgttctt ggccaatgat tcgatttctt catggtgaag gagatacata
    18241 tctttttgtc caacttgagg gaaatcatac tcacgcttga tagacatagc ttcgacttcg
    18301 acccatttcc catcttccca gtaagaacct ggcgcagaaa cctcacggag attaatttct
    18361 ggattaaagt tggttgcaaa tggataaccg tggtcaccgc cattacagtc taaaatgtcg
    18421 atataatgga tttcatcaaa atagtgtttg agggcataag ctgaaaagac actagttaca
    18481 cctgggtcaa aaccagaacc aagaagagca gtcaagcctg cttctttgaa tttctcttga
    18541 taagcccact gccatgagta gtcaaagtag gctgtaaaac caagttcctt acaacgtttt
    18601 tcgtagatag cacgccactc agggtcttct gtgtcttctg cttcgtagtt ggctgtatcg
    18661 atatagtgaa cacctgttgc caaacaagca tccataatgg ttaaatcttg ataaggcaga
    18721 gctacattca aaacagcttc tggtttgtag ctttcaatca gggcaatcac ttcttcaacc
    18781 ttgtcagcat caagtgctgc agtttcaatt ttagtacttg ttttgccttc tagcttcgct
    18841 ttcaagtcat cgcattttga cttggtacgg ctagcaatca taatctctgt aaatgtttcg
    18901 ctatcttgac aaatctttga aatagcaact tgggcaacgc ccccacaacc aataactagt
    18961 aaacgactca tttttttcct tcctcttctt ctaaaatgtc ctcaacatac ttgggcaaca
    19021 taaaggatcc cacgtgtaag tttgcagtgt agtattctgt gaaaagctgg cgttttttcc
    19081 aaccttcctt gtcaaaatct ttgacagggt ggtatttttt cgatgcaaat ccaaacaacc
    19141 aatagccagc tgggctagtt ggaatatggg cctgataaac ccgactgatt ggaaaggctt
    19201 gattgacctt gcggtgcatg cttcggcagg ccgactcatc ctcgtcaaag aagggactcc
    19261 catgctggta aatcatgatg ccgtcttcct tcagagctcg ataactattg ccgtagaatt
    19321 ccttggtaaa gagtccttcc gtatggccaa atggatctgt cgcatcgttg atgataatat
    19381 cgtaatcatc ttcgcagttt cgcaaaaagc gtagcccatt ttggtagtaa atggtaacac
    19441 gaggatcatc tagccctgca gcaaagtctg ggaaatactc acgacagacc tcgaccaaca
    19501 tctcatccgg ttccacgata tcgatttgtt ccagttcagg atagagtgtt aatacttggg
    19561 caacaccgcc gtcaccaccc ccaataacca atactttctt tggatttggg tggacagcca
    19621 tgggaacgtg aacggtcatt tcattgtaga cgaaatcatc cgcatctgag aacaagacat
    19681 ggccatttaa aatcagtatt ttcccaaaag ctggcgtatc caagacttcg atatcctgcc
    19741 attcactttt tccagcgtaa agttgcttgg ctgttctcag agacaatttg acatctggag
    19801 tatgaacttc agaaaaccat aaatccatct atttctcctt atattatatt tagcgcagtt
    19861 agctactgcc aaagcccaag tggtatactt ggaataagcc actgtggatt agtttattcc
    19921 ctccaatcgc ttgacgattt ccgaaaggct ctaaccacag ttttttgttt caattggtaa
    19981 tgagtttgat aacgcataga cgttttatct cgtctaaggt aacaaggcaa aaaattcgtg
    20041 gataaccaag tagacttgaa atactacatc tggaggtact cccatgcttt atgtgggcat
    20101 tgatgtcgct aaaaataaac acgatgttac agccttgaat gttccaggaa aaactgttct
    20161 taaaccactc actttttcaa ataataaagc tggttttgaa ctcttagatc tgtctcttcg
    20221 acaactcaac caagactgtc tcatcgctct tgaaaatacc ggacattatg cctttaatct
    20281 actgaacttc ctgcatgaac aaggatataa agtttacacc tacaatcctt tgctcatcaa
    20341 ggaatttgcc aaatcattat cacttcacaa gactaaaacg gataagaaag acgctcatgg
    20401 catcgctctt aaacttcttt ctgaccccaa tcgtgaacaa tttcaacacg ataatcggca
    20461 agtagaacta aaaatactgg ctagacatat tcatcgtctc aagaaaaaca gtctgattgg
    20521 aaagtacaat acactcgttg tcttgatatc atctttcctg agttggataa aatcgttgga
    20581 aagcattcag aatataccta ccaactcttg acacgctacc ctaatcctca gaaaaggatt
    20641 gaggcaggat ttgataagct gatagaaatt aagcgattga ccgcttctaa ttcaagggct
    20701 ttttgccgtg ctctaaaatc atcgccaaat catcaaattg aaataagaaa tagtttagat
    20761 aaaactattg acttttctta tagtttgtct ttctcttaat aacgttgata tgattgacct
    20821 ctgaatcttc cgtcccttgg agggagcaac cacgttcctt ggcgaattgg atatagtcta
    20881 caatttctcg tgtaatgcgt tcaccaggag ccaagatagg aatccctgga ggatagcaca
    20941 tgacaaattc tccacagacc tgtccaacag actcatctaa ggtcaaactt tttctctctg
    21001 aatagaaggc ttcttgtgga gacagcacca actcgggctg aatatattct cctgctatca
    21061 aatcttttcc atctcttgaa tagagtctct taatatcagc cagagcacca accaagcgct
    21121 cgatgtcttg gatgcggtcg ccgatggaaa tataggccaa gatattgccg atatcaccaa
    21181 actcgatctg aatgtcgtat tcgtctcgca agaggtcata aacctcgata cctgttaagc
    21241 caataccctg agtgtaaact gacagcttag ttacgtcaaa atcgcaaacc gaaacaccgt
    21301 ctattaactc ttttgagtag gcatagtagc caccgatagc attgatttca cggcgggcat
    21361 actcagatag ctcaatgact ttctcaaacg actctttacc acgaagggcc aagttgcgac
    21421 gtgaaatatc caaactagcc atcaacaagt aagaggcaga tgtagactga gtcaggttaa
    21481 ttatctgacg aacgtattca gaattcatct gctccccgat taaaagaagc gaactttgtg
    21541 tcaaactccc accagactta tgcatggaaa ctgctgccat atcagctcct gcatccatag
    21601 cagaaattgg aagtttacca gtgaaatgca aatgcgctcc atgggcttca tctactaaaa
    21661 ccatcatgcc agcttcatga gccatttctg tcaacccctt taggtctgaa cagatgccgt
    21721 agtaagtagg attgttgatt aggatagcct tagcatctgg atggtccttt atggcctgtg
    21781 ctactcggtc attttcaaga cctaaagcga taccaatctt aggatctaca ctcatctcga
    21841 tatagatggg aatggcacca catagaacca acgcattgat agcagattta tggacatttc
    21901 gtggcagaat aatcttatct cctgccttgc aggttgccag aatcatagtc tgcaccgatg
    21961 aagttgttcc accaatcatt agaaaggcat ggctagctcc aaaagcatct gcagccagct
    22021 cctctgcatc acgaataatc gaaataggat ggcctaaatt atccaagggt ttcatcgaat
    22081 tgacatcaat gcctacacat ttttctccta agagttcgac aagttctgga tttccccgtc
    22141 cacgcttgtg acctggaaca tcaaagggaa caatcctttt cttgcgtaac ttcaccaagg
    22201 cctcataaat tggggcttgg ttttgatcta actctttcaa aacatactcc tttcaatatt
    22261 tttaggacct tatgaaaact aaggaactaa aggttgactc atgaaaaaag agcaggtttt
    22321 cacctgctct gcaatcttct gacgtgttta ttttggtttc tgttgagtat gtctgttccc
    22381 gatgtttcct aactctctag tagcaaatat tacgtacttt attgatcgtt tcacaagatg
    22441 acgtgtgctt tcaccacact aaaaatttat gaattaggac aagtgtccta acatcaactt
    22501 ataaaagtag gcttttaacc ctatcaataa tgtggctttt caaccacgct tcggcattca
    22561 accctgcctg tccgtaggca ttttttactc gggtttatat ttgctagaaa acatcatctc
    22621 attttctaag ctttattact atatcatgtt tttaagaact tgtaaagtat tttttgataa
    22681 aaaacaaaaa tatagtagat tgaaactaga atagtacacc tctgcttcta aaacattgtt
    22741 agaaatagat tttactgtcc tgatcgattt gttctgttct tgtttcattt tactatatgt
    22801 tcgtaaatga aagttctata atgaagttag ccacccagcc ctcctaaaaa ttagatggtt
    22861 caactagctg atagctcttg taggcataag aaaacacctc tgtgttatac ttgttgttca
    22921 accacaaaca caagaaaggc acagagatgc aagacaatta tactacaaaa gccaaacatt
    22981 tgacaatcga tagccgtcgc ttaatcgaaa gatggaaaaa agaaggaaaa tcaaatagag
    23041 aaattgcctc tctacttgga aaagctcctc aaactatcca cactgaaatc aagcgtagga
    23101 cagtccgaca atgtcttgga aaagggcgct tcaaagaggt ttattctgcc gactatgctc
    23161 aacagtctta tgaaaataat cgcaagcact cggtcaagag atcaagcgtg accaaggaac
    23221 taaaggaaaa gattctccac tatcataacc aaaaattttc gcctgaaatg atggttatgg
    23281 ctaaaggggt taacgtggga atttcaacca tttactattg gattcatcat ggaaaattgg
    23341 ggttaagcaa gcaggatctg ctttacccta gaaaaggaaa agcgcttaag aaacaggcta
    23401 gcaccaactt taaacctgct ggtcaatcca tcgaacagcg gcctgaagct atcaatcttc
    23461 gcttggagaa tgggcattat gagattgata cggttctact tacgagatcg aaaaactact
    23521 gcttgcttgt cttgacggat cgaaagagta gacatcagat catccgattg attccaaata
    23581 aaagtgctga ggtggtcaat caggctctaa aactcatctt aaaacaacac
//
LOCUS       DAVHTH010000033        21865 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.033, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000033 DAVHTH010000000
VERSION     DAVHTH010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21865)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21865)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21865
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.033"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            134..958
                     /gene="mutM"
                     /locus_tag="VVR63_001330"
     CDS             134..958
                     /gene="mutM"
                     /locus_tag="VVR63_001330"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001114577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HEU6129345.1"
                     /translation="MPELPEVETVCRGLEKLIIGKKISSIEIRYPKMIKTDLEEFQRE
                     LPSQIIESMGRRGKYLLFYLTDKVLISHLRMEGKYFYYPDQGPERKHAHVFFHFEDGG
                     TLVYEDVRKFGTMELLVPDLLDAYFISKKLGPEPSEQDFDLQVFQSALAKSKKPIKSH
                     LLDQTLVAGLGNIYVDEVLWRAQVHPARSSQTLTAEEATAIHDQTIAVLGQAVEKGGS
                     TIRTYTNAFGEDGSMQDFHQVYDKTGQECVRCGTIIEKIQLGGRGTHFCPNCQRRD"
     gene            958..1563
                     /locus_tag="VVR63_001331"
     CDS             958..1563
                     /locus_tag="VVR63_001331"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HEU6129346.1"
                     /translation="MRKIIGITGGIASGKSTVTNFLRQQGFQVVDADAVVHQLQKPGG
                     RLFEALVQHFEQEIILENGELNRPLLASLIFSNPEEQKWSKQIQGEIIREELATLREQ
                     LAQTEEIFFMDIPLLFEQDYSDWFAETWLVYVDRDAQVERLMKRDQLSKDEAESRLAA
                     QWPLEKKKDLASQVLDNNGNQNQLLNQVHILLEGGRQDDRD"
     gene            1550..2749
                     /locus_tag="VVR63_001332"
     CDS             1550..2749
                     /locus_tag="VVR63_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HEU6129347.1"
                     /translation="MTEINWKDNLRIAWFGNFLTGASISLVVPFMPIFVENLGVGSEQ
                     VAFYAGLAISVSAISAALFSPIWGILADKYGRKPMMIRAGLAMTITMGGLAFVPNIYW
                     LIFLRLLNGVFAGFVPNATALIASQVPKEKSGSALGTLSTGVVAGTLTGPFIGGFIAE
                     LFGIRTVFLLVGSFLFLAAILTICFIKEDFQPVAKEKAIPTKELFTSVKYPYLLLNLF
                     LTSFVIQFSAQSIGPILALYVRDLGQTENLLFVSGLIVSSMGFSSMMSAGVMGKLGDK
                     VGNHRLLVVAQFYSVIIYLLCANASSPLQLGLYRFLFGLGTGALIPGVNALLSKMTPK
                     AGISRVFAFNQVFFYLGGVVGPMAGSAVAGQFGYHAVFYATSLCVAFSCLFNLIQFRT
                     LLKVKEI"
     gene            2749..2898
                     /gene="rpmG"
                     /locus_tag="VVR63_001333"
     CDS             2749..2898
                     /gene="rpmG"
                     /locus_tag="VVR63_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEU6129348.1"
                     /translation="MRVKINLKCSSCDSINYLTSKNSKTHPDKIEVLKYCPKERKVTL
                     HLESK"
     gene            2938..3171
                     /gene="secG"
                     /locus_tag="VVR63_001334"
     CDS             2938..3171
                     /gene="secG"
                     /locus_tag="VVR63_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HEU6129349.1"
                     /translation="MYNLLLTILLVLSVVIVIAIFMQPTKNQSSNVFDASSGDLFERS
                     KARGFEAVMQRLTGILVFFWLAIALALTVLSSR"
     gene            3273..5627
                     /gene="rnr"
                     /locus_tag="VVR63_001335"
     CDS             3273..5627
                     /gene="rnr"
                     /locus_tag="VVR63_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HEU6129350.1"
                     /translation="MKDRIKEYLQDKGKVTVNDLAQALGKDSSKDFRELIKTLSLMER
                     KHQIRFEEDGSLTLEAKKKHEITLKGIFHAHKNGFGFVSLEGEEDDLFVGKNDVNYAI
                     DGDTVEVVIKKVADRNKGTAAEAKIIDILEHSLTTVVGQIVLDQEKPKYVGYIRSKNQ
                     KISQPIYVKKPALKLEGTEVLKVFIDKYPSKKHDFFVASVLDVVGHSTDVGIDVLEVL
                     ESMDIVSEFPEAVVKEAESVPDAPSQKDMEGRLDLRDEITFTIDGADAKDLDDAVHIK
                     ALKNGNLELGVHIADVSYYVTEGSALDKEALNRATSVYVTDRVVPMLPERLSNGICSL
                     NPQVDRLTQSAIMEIDKHGRVVNYTITQTVIKTSFRMTYSDVNDILAGDEEKRKEYHK
                     IVSSIELMAKLHETLENMRVKRGALNFDTNEAKILVDKQGKPVDIVLRQRGIAERMIE
                     SFMLMANETVAEHFSKLDLPFIYRIHEEPKAEKVQKFIDYASSFGLRIYGTASEISQE
                     ALQDIMRAVEGEPYADVLSMMLLRSMQQARYSEHNHGHYGLAADYYTHFTSPIRRYPD
                     LLVHRMIRDYGRSKEIAEHFEQVIPEIATQSSNRERRAIEAEREVEAMKKAEYMEEYV
                     GEEYDAVVSSIVKFGLFVELPNTVEGLIHITNLPEFYHFNERDLTLRGEKSGITFRVG
                     QQIRIRVERADKMTGEIDFSFVPSEFDVIEKGLKQSSRSGRGRGSNRRSDKKEDKRKS
                     GRSNDKRKHSQKDKKKKGKKSFYKEVAKKGAKHGKGRGKGRRTK"
     gene            5590..6057
                     /gene="smpB"
                     /locus_tag="VVR63_001336"
     CDS             5590..6057
                     /gene="smpB"
                     /locus_tag="VVR63_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HEU6129351.1"
                     /translation="MAKGEGKVVAQNKKARHDYTIVDTLEAGMVLTGTEIKSVRAARI
                     NLKDGFAQVKNGEVWLSNVHIAPYEEGNIWNQEPERRRKLLLHKKQIQKLEQETKGTG
                     MTLVPLKVYIKDGYAKLLLGLAKGKHDYDKRESIKRREQNRDIARVMKAVNQR"
     gene            6073..6933
                     /gene="tehB"
                     /locus_tag="VVR63_001337"
     CDS             6073..6933
                     /gene="tehB"
                     /locus_tag="VVR63_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase TehB"
                     /protein_id="HEU6129352.1"
                     /translation="MEKLVAYKRMPLWNKQTMPEAVQQKHNTKVGTWGKITVLKGALK
                     FIELTEEGEVLAEHLFEAGADNPMAQPQAWHRVEAATDDVEWYLEFYCKPEDYFAKKY
                     NTNPVHSEVLEAMQTVKQGKALDLGCGQGRNSLFLAQQDFDVTAVDQNGLALEILQSI
                     VEQEDLDMPVGLYDINSASIEQEYDFIVSTVVLMFLQADRIPAIIQNMQEKTSVGGYN
                     LIVCAMDTEDYPCSVNFPFTFKEGELADYYKDWELVKYNENPGHLHRRDENGNRIQLR
                     FATLLAKKIK"
     gene            7006..7959
                     /gene="coiA"
                     /locus_tag="VVR63_001338"
     CDS             7006..7959
                     /gene="coiA"
                     /locus_tag="VVR63_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000495911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HEU6129353.1"
                     /translation="MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTH
                     FAHKSLKDCDFFFENESPEHLANKESLYHWLKKETKVQLEYPLSELKQIADVFVNGNL
                     ALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
                     YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTV
                     SEDKDICRYIRQQLYYQNLFWMKEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIE
                     QDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE"
     gene            7978..9780
                     /gene="pepF"
                     /locus_tag="VVR63_001339"
     CDS             7978..9780
                     /gene="pepF"
                     /locus_tag="VVR63_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEU6129354.1"
                     /translation="MVLQRNEINEKDTWDLSTIYPTDQAWEEALKDLTEQLETVAQYE
                     GHLLDSADNLLEITEFSLEMERQIEKLYVYAHMKNDQDTREAKYQEYYAKAMTLYSQL
                     DQAFSFYEPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLQGKDHVLSQREEELLAGA
                     GEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGTYTRLMESKKREVRRGAYQAL
                     YATYEQFQHTYAKTLQTNVKVQNYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRK
                     HLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYSFTYQEALKKAEDALAVLGEDYL
                     SRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNSFMLLNWQDNLDNLFTLVHETGHSM
                     HSSYTRETQPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFR
                     GTVFRQTQFAEFEHAIHQADQNGEVLTSDFLNKLYADLNQEYYGLSKEDNPEIQYEWA
                     RIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSDYPLNVMRKA
                     GVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA"
     gene            9782..10495
                     /locus_tag="VVR63_001340"
     CDS             9782..10495
                     /locus_tag="VVR63_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HEU6129355.1"
                     /translation="MVESYSKNANHNMRRPVVKEEIVDLMRQRQKQVTGFLKELEDFA
                     RKENIPIIPHETVAYFRFLMETMQPKNILEIGTAIGFSALLMAEHAPNAKITTIDRNP
                     EMIGFAKENFAQFDSRKQITLLEGDAVDVLSTLTESYDFVFMDSAKSKYIVFLPEILK
                     HLEVGGVVVLDDIFQGGDVAKDIMEVRRGQRTIYRGLQKLFDATLDNPELTATLVPLG
                     DGILMLRKNVADVQLSESE"
     gene            10562..11503
                     /gene="prsA"
                     /locus_tag="VVR63_001341"
     CDS             10562..11503
                     /gene="prsA"
                     /locus_tag="VVR63_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HEU6129356.1"
                     /translation="MKKKLLAGAITLLSVATLAACSKGSEGADLISMKGDVITEHQFY
                     EQVKNNPSAQQVLLNMTIQKVFEKQYGSELDDKEVDDTIAEEKKQYGENYQRVLSQAG
                     MTLETRKAQIRTSKLVELAVKKVAEAELTDEAYKKAFDEYTPDVTAQIIRLNNEDKAK
                     EVLEKAKAEGADFAQLAKDNSTDEKTKENGGEITFDSASTEVPEQVKKAAFALDVDGV
                     SDVITATGTQAYSSQYYIVKLTKKTEKSSNIDDYKEKLKTVILTQKQNDSTFVQSIIG
                     KELQAANIKVKDQAFQNIFTQYIGGGDSSSSSSTSNE"
     gene            complement(11620..11961)
                     /locus_tag="VVR63_001342"
                     /pseudo
     CDS             complement(11620..11961)
                     /locus_tag="VVR63_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            12375..12470
                     /locus_tag="VVR63_001343"
                     /pseudo
     CDS             12375..12470
                     /locus_tag="VVR63_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(12724..13344)
                     /locus_tag="VVR63_001344"
     CDS             complement(12724..13344)
                     /locus_tag="VVR63_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEU6129357.1"
                     /translation="MKLYFVRHGRTLWNQEGRFQGASGDSPLLPESIETLKRLGQYLK
                     EIPFDQIYSSDLPRAVKSAEIIQSQLYTPCSLEIVPNLREWQLGKLEGLKIATLEAIY
                     PQQIQAFRSNLAQFDTRMFGAESLYSTTQRTIQFIKSLKDSPAERILIVGHGANLTAS
                     LRTLLGYKEPLLRKDGGLANASLTIIETHDFETFTLNTWNDTSYQS"
     gene            complement(13344..13826)
                     /locus_tag="VVR63_001345"
     CDS             complement(13344..13826)
                     /locus_tag="VVR63_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HEU6129358.1"
                     /translation="MAKKVKIKKTLVEQILSKAAIPHQGIQINALEGELPQGYERDQI
                     FKTLALLGDKTGPIIGIVPITQHLSEKKLAKISGNKKVSMIPQKDLEKTTGYIHGANN
                     PVGIRQKHNYPIFIDKIALDLDQMIVSAGEVGHSIIVAPQDLASFVKADFVDILEDIK
                     "
     gene            complement(13826..14668)
                     /locus_tag="VVR63_001346"
     CDS             complement(13826..14668)
                     /locus_tag="VVR63_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HEU6129359.1"
                     /translation="MLSWLARVIKGIVIALGFILPGISGGVLAAILGIYERMIGFLAH
                     PFKDFKENVLYFIPVAIGMLLGIGLFSYPIEYLLENYQVFVLWSFAGAIIGTVPSLLK
                     ESTRESDRDKIDLAWLWTTFIISGLGLYALNFVVGTLSASFLNFVLAGALLALGVLVP
                     GLSPSNLLLILGLYAPMLTGFKTFDFLGTFFPIGIGAGATLIVFSKLMDYALNNYHSR
                     VYHFIIGIVLSSTLLILIPNAGNAESIQYTGLSLVGYVIIAFFFALGIWLGIWMSQLE
                     DKYK"
     gene            complement(14763..15563)
                     /locus_tag="VVR63_001347"
     CDS             complement(14763..15563)
                     /locus_tag="VVR63_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HEU6129360.1"
                     /translation="MRKQIHPLILFSFFGIMMFILIINRPLNDSQSFKTKSNIAQIEA
                     QALKHLDKPIIDLSGWQRPEEINYDALSQNISGAIVRVHSGAQTTKENDASFINGIDK
                     TYKSHITELQKRNVPVAVYAYVAGKSVQEMEKAAEVFYNAASPYSPSYYWLDVEDKTM
                     SNMNEGVENFRAKLASLGAKNIGIYVGVYFMEEHSIDTGKFTSVWIPSYGSDSGFLES
                     SPKTDLDYDIHQYTSKGKIAGFDHDLDINVISPLKNKEETFRKLFLKP"
     gene            15707..17086
                     /gene="glmU"
                     /locus_tag="VVR63_001348"
     CDS             15707..17086
                     /gene="glmU"
                     /locus_tag="VVR63_001348"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HEU6129361.1"
                     /translation="MSNFAIILAAGKGTRMKSDLPKVLHKVAGISMLEHVFRSVGAIQ
                     PEKTVTVVGHKAELVEEVLAEQTEFVTQSEQLGTGHAVMMTEPILEGLSGHTLVIAGD
                     TPLITGESLKNLIDFHINHKNVATILTAETDNPFGYGRIVRNDNAEVLRIVEQKDATD
                     FEKQIKEINTGTYVFDNERLFEALKNINTNNAQGEYYITDVIGIFRETGEKVGAYTLK
                     DFDESLGVNDRVALATAESVMRRRINHKHMVNGVSFVNPEATYIDIDVEIAPEVQIEA
                     NVILKGQTKIGAETVLTNGTYVVDSTIGAGAVITNSMIEESSVADGVTVGPYAHIRPN
                     SSLGAQVHIGNFVEVKGSSIGENTKAGHLTYIGNCEVGSNVNFGAGTITVNYDGKNKY
                     KTVIGDNVFVGSNSTIIAPVELGDNSLVGAGSTITKDVPADAIAIGRGRQINKDEYAT
                     RLPHHPKNQ"
     gene            17096..17641
                     /locus_tag="VVR63_001349"
     CDS             17096..17641
                     /locus_tag="VVR63_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU6129362.1"
                     /translation="MEFEEKTLSRKEIYQGPIFKLVQDQVELPEGKGTAQRDLIFHNG
                     AVCVLAVTDEQKLILVKQYRKAIEAVSYEIPAGKLEVGENTAPVAAALRELEEETAYT
                     GKLELLYDFYSAIGFCNEKLKLYLASDLTKVENPRPQDEDETLEVLEVSLEEAKELIQ
                     SGHICDAKTIMAVQYWELQKK"
     gene            17653..17967
                     /locus_tag="VVR63_001350"
     CDS             17653..17967
                     /locus_tag="VVR63_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="foldase"
                     /protein_id="HEU6129363.1"
                     /translation="MGKSLLTDEMIERANRGEKISGPPLLDDNEETKILPTSSSRFGY
                     ANPKDHGFSQETLKIQVEPSIHKSRRIENTKRNVFNSKLNKILFAVIFLLILLVLAMK
                     LL"
     gene            17984..18676
                     /locus_tag="VVR63_001351"
     CDS             17984..18676
                     /locus_tag="VVR63_001351"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HEU6129364.1"
                     /translation="MKIGIIAAMPEELAYLVQHLDNTQEQVVLGNTYHTGTIASHEVV
                     LVESGIGKVMSAMSVAILADHFQVDALINTGSAGAVAEGIAVGDVVIADKLAYHDVDV
                     TAFGYAYGQMAQQPLYFESDKTFVAQIQESLSQLDQNWHLGLIATGDSFVAGNDKIEA
                     IKSHFPEVLAVEMEGAAIAQAAHALNLPVLVIRAMSDNANHEANIFFDEFIIEAGRRS
                     AQVLLTFLKALD"
     gene            18753..19244
                     /gene="rocS"
                     /locus_tag="VVR63_001352"
     CDS             18753..19244
                     /gene="rocS"
                     /locus_tag="VVR63_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein RocS"
                     /protein_id="HEU6129365.1"
                     /translation="MSIEMTVSEIAEVLGLSRQAINNRVKELPEEDTDKNDKGVTVVT
                     RSGLIKLEEIYKKTIFEDEPVSEDVKQRELMEILVDEKNAEILRLYEQLKAKDRQLSE
                     KDEQMRIKDRQIAEKDKQLDQQQQLTLQAMKDQENLKLELDQAKEEVQSTKKGFFARL
                     FGG"
     gene            19342..19932
                     /locus_tag="VVR63_001353"
     CDS             19342..19932
                     /locus_tag="VVR63_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HEU6129366.1"
                     /translation="MERLEDYIAFDLEFNQHEGQTHLIQVSAVRFRDGREIDAYDSYV
                     HTSVPLKSFINGLTGITAETLKDAPPVEKVLEEFQEFVGSLLMIGYNAAKSDLPILAE
                     HGLDYSQQYKVDLYDEAFERRSSDLHGIANLKLQTVASFLGFQGQSHNSLEDARMTAR
                     VYESFLESDQARELLETESSLSNNPFGGLNLSQLFD"
     gene            19941..21704
                     /locus_tag="VVR63_001354"
     CDS             19941..21704
                     /locus_tag="VVR63_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HEU6129367.1"
                     /translation="MKPEKPKKLGLKQIYLNLDKILFLFFLIFMIVEYLWVPFNSWLA
                     SFLLDQTGYLFISYNNVLAILTHSPLISLAFLALIVINLLVAYFQIGLLFIGARHLLY
                     NEKRRLIEYIRKVFHESFGFMKKLTCAKALFIFFYIAMLFPFIRKMLKIYYLNKIVIP
                     EFIQAYLEDKYWMWWLSILLLSLIFLYVSVRLMFALPKIVYDQLTVREAVMFSLEKTK
                     KRVTFYAWNLFYILLKAHLLFYLPLIPSLLAQTLVDDITQRESLILGILNFVVIKNLY
                     YMALTYFLVKFVSFLTGKELDMLPRREKDHIVRWGVMTCASLFFALEGYIYLEAPMVH
                     LPQLISHRGVSNANGIQNTVESLETTAQLKPDLVETDVQETKDGQFVMMHDANLKNLA
                     GINKSPQDLNLEELKGIDIFENGYQTKISSFEDYLSRANELGQKLLIEIKTSKKDSPD
                     MMNRFLARYAAKLKIYGHQIQSLDYHVVEKVRQYDAELPVYFIMPYNSVFPKTRATGY
                     TMEYSTLDEYFVSKLWTTDQKLYVWTVNDSEAISKSLHLGVDGVITDDLEKVQREIEV
                     AQEDPEYTDLLLKKALEFFEF"
BASE COUNT         6740 a         3979 c         4733 g         6413 t
ORIGIN      
        1 agaaacctgg gtcaaggtca agaaaaactg gcgcgataaa aagctagatt tggctgactt
       61 tggctataat gaaaaagaat actaagtaga ggtgggctca tgcctgcttc ttgtttttac
      121 agaaggagga cttatgcctg aattacctga ggttgaaacc gtttgtcgtg gcttagaaaa
      181 attgattata ggaaagaaga tttcgagtat agaaattcgc taccccaaga tgattaagac
      241 ggatttggaa gagtttcaaa gggaattgcc tagtcagatt atcgagtcaa tgggacgtcg
      301 tggaaaatat ttgctttttt atctgacaga caaggtcttg atttcccatt tgcggatgga
      361 gggcaagtat ttttactatc cagaccaagg acctgaacgc aagcatgccc atgttttctt
      421 tcattttgaa gatggtggca cgcttgttta tgaggatgtt cgcaagtttg gaaccatgga
      481 actcttggtg cctgaccttt tagacgccta ctttatttct aaaaaattag gtcctgaacc
      541 aagcgaacaa gactttgatt tacaggtctt tcaatctgcc cttgccaagt ccaaaaagcc
      601 tatcaaatcc catctcctag accagacctt ggtagctgga cttggcaata tttatgtgga
      661 tgaggttctc tggcgagctc aggttcatcc agctagatct tcccagactt tgacagcaga
      721 agaagcgaca gctattcatg accaaaccat tgctgttttg ggccaggctg ttgaaaaagg
      781 cggttccacc attcggactt ataccaatgc ctttggggaa gatggaagca tgcaggactt
      841 tcatcaggtc tatgataaga ctggtcaaga gtgtgtacgc tgtggtacca tcattgagaa
      901 aattcaacta ggcggacgag gcacccactt ttgtccaaac tgtcaaagga gggactgatg
      961 agaaaaatca tcggaatcac tgggggaatt gcctctggta agtcaactgt gacaaatttt
     1021 ctaagacagc aaggctttca agtagtggat gccgacgcag tcgtccacca actacagaaa
     1081 cctggtggtc gtctgtttga ggctctagta cagcactttg agcaagaaat cattcttgaa
     1141 aacggagaac tcaatcgccc tctcctagct agtctcatct tttcaaatcc tgaagagcaa
     1201 aaatggtcga agcaaattca aggggagatt atccgtgagg aactggctac tttgagagaa
     1261 cagttggctc agacagaaga gattttcttc atggatattc ccctactttt tgagcaggac
     1321 tacagcgatt ggtttgctga gacttggttg gtctatgtgg accgagatgc ccaagtagaa
     1381 cgcttaatga aaagggacca gttgtccaaa gatgaagctg agtctcgtct ggcagcccag
     1441 tggcctttag aaaaaaagaa agatttggcc agccaggttc ttgataataa tggcaatcag
     1501 aaccagcttc ttaatcaagt gcatatcctt cttgagggag gtaggcaaga tgacagagat
     1561 taactggaag gataatctgc gcattgcctg gtttggtaat tttctgacag gagccagtat
     1621 ttctttggtt gtacctttta tgcccatctt cgtggaaaat ctaggtgtag ggagtgagca
     1681 agtcgctttt tatgcaggct tagcaatttc tgtctctgct atttccgcgg cgctcttttc
     1741 tcctatttgg ggtattcttg ctgacaaata cggccgaaaa cccatgatga ttcgggcagg
     1801 tcttgctatg actatcacta tgggaggctt ggcctttgtc ccaaatatct attggttaat
     1861 ctttcttcgt ttactaaacg gtgtatttgc aggttttgtt cctaatgcaa cggcactgat
     1921 agccagtcag gttccaaagg agaaatcagg ctctgcctta ggtactttgt ctacaggcgt
     1981 agttgcaggt actctaactg gcccctttat tggtggcttt atcgcagaat tatttggcat
     2041 tcgtacagtt ttcttactgg ttggtagttt tctattttta gctgctattt tgactatttg
     2101 ctttatcaag gaagattttc aaccagtagc caaggaaaag gctattccaa caaaggaatt
     2161 atttacctcg gttaaatatc cctatctttt gctcaatctc tttttaacca gttttgtcat
     2221 ccaattttca gcccaatcga tcggccctat tttggctctt tatgtacgcg acttagggca
     2281 gacagagaat cttctttttg tctctggttt gattgtgtcc agtatgggct tttccagcat
     2341 gatgagtgca ggagtcatgg gcaagctagg tgacaaggtg ggcaatcatc gtctcttggt
     2401 tgtcgcccag ttttattcag tcatcatcta tctcctctgt gccaatgcct ctagccccct
     2461 tcaactagga ctctatcgtt tcctctttgg cttgggaacc ggtgccttga ttcccggggt
     2521 taatgcccta ctcagcaaaa tgactcccaa agccggcatt tcgagggtct ttgccttcaa
     2581 tcaggtattc ttttatctgg gaggtgttgt tggtcccatg gcaggttctg cagtagcagg
     2641 tcaatttggc taccatgctg tcttttatgc gacaagcctt tgtgttgcct ttagttgtct
     2701 ctttaacctg attcaatttc gaacattatt aaaagtaaag gaaatctagt gcgagtaaaa
     2761 attaatctca aatgctcctc ttgtgacagt atcaattacc taaccagtaa aaattcaaaa
     2821 acccatccag acaagattga ggttttaaag tattgtccca aggaaagaaa agtaacccta
     2881 catcttgaat ctaagtagat tttatggtaa aataataggg attttaagga gtttgatatg
     2941 tataacctat tattaaccat tttattagta ttatctgttg tgattgtgat tgcaattttc
     3001 atgcaaccaa ccaaaaacca atccagcaat gtatttgatg ccagttcagg tgatttgttt
     3061 gaacgcagta aagctcgcgg ttttgaagct gtaatgcagc gtttgacagg gattttagtc
     3121 tttttctggc tagccattgc cttagcattg acggtattat caagtagata agaaaataat
     3181 gggcaggact aggtctttgc ctctttttat ttttaaagga tgtttgagaa ggttttacag
     3241 taaaagaaaa ttaaaaaatc tagaaagaaa atatgaaaga tagaataaaa gaatatttac
     3301 aagacaaggg aaaggtgact gttaatgatt tggctcaggc tttgggaaaa gacagttcca
     3361 aggattttcg tgagttgatt aaaaccttgt ccttaatgga aagaaagcac cagattcgct
     3421 ttgaagaaga tggcagtctg accttggaag ccaagaaaaa acatgagatt accctcaagg
     3481 ggatttttca tgcccataaa aatggttttg gctttgtcag cctagaaggg gaagaggacg
     3541 acctttttgt aggaaagaac gatgtcaact atgctattga tggtgatacc gttgaggtcg
     3601 tcatcaagaa agtcgctgac cgcaataagg gaacagcagc agaagccaaa attattgata
     3661 tcctagaaca cagtttaaca acagttgtcg ggcaaatcgt tctggatcag gaaaagccta
     3721 agtatgttgg ctatattcgt tcaaaaaatc agaaaattag tcaaccgatt tatgttaaga
     3781 aaccagccct aaaattagaa ggaacagaag ttctcaaagt ctttatcgat aaatatccaa
     3841 gcaagaaaca tgatttcttt gtcgcgagtg ttctcgatgt ggtgggacac tcaacggatg
     3901 tcggaattga tgttcttgag gtcttggaat caatggacat tgtatccgag tttccagaag
     3961 ctgttgttaa ggaagcagaa agtgtgcctg atgctccgtc tcaaaaggat atggaaggcc
     4021 gtctggatct aagagatgaa attaccttta ccattgacgg tgcggatgcc aaggacttgg
     4081 acgatgcagt gcatatcaag gctctgaaaa atggcaatct ggagcttggg gttcacatcg
     4141 cagatgtttc ttattatgtg accgaggggt ctgcccttga caaggaagcc cttaaccgtg
     4201 cgacttctgt ttacgtgaca gaccgagtgg tgccaatgct tccagaacga ctatcaaatg
     4261 gcatctgctc tctcaatccc caagttgacc gcctgaccca gtctgctatt atggagattg
     4321 ataaacatgg tcgtgtggtc aactatacca ttacacaaac agttatcaag accagttttc
     4381 gtatgaccta tagcgatgtc aatgatatcc tagctggcga tgaagaaaag agaaaagaat
     4441 atcataaaat tgtatcaagt atcgaactca tggccaagct tcatgaaact ttagaaaaca
     4501 tgcgtgtgaa acgtggagct ctcaattttg ataccaatga agcgaagatt ttagtggata
     4561 aacaaggtaa gcctgttgat atcgttcttc ggcagcgtgg cattgccgag cggatgattg
     4621 agtcttttat gttgatggct aatgaaacag ttgccgaaca tttcagcaag ttggatttgc
     4681 cttttatcta tcgaattcac gaggaaccta aggctgaaaa ggttcagaag tttattgatt
     4741 atgcttcgag ttttggcttg cgtatttatg ggactgccag tgagattagt caggaggcac
     4801 ttcaagacat catgcgtgct gttgagggag aaccttatgc agatgtattg tccatgatgc
     4861 ttcttcgctc tatgcagcag gctcgttatt cggagcacaa tcacggccac tatggactag
     4921 ctgctgacta ttatactcac tttaccagtc caattcgtcg ttatccagac cttcttgttc
     4981 accgtatgat tcgggattac ggccgttcta aggaaatagc agagcatttt gaacaagtga
     5041 ttccagagat tgcgacccag tcttccaacc gtgaacgtcg tgccatagaa gctgagcgtg
     5101 aagtcgaagc catgaaaaag gctgagtata tggaagaata cgtgggtgaa gagtatgatg
     5161 cagttgtatc aagtattgtc aaattcggtc tctttgtcga attgccaaac acagttgaag
     5221 gcttgattca catcactaat ctacctgaat tttatcattt caatgagcgt gatttgactc
     5281 ttcgtggaga aaaatcaggt atcactttcc gagtgggtca gcagatccgt atccgtgttg
     5341 aaagagcgga taaaatgact ggagagattg atttttcatt cgtacctagt gagtttgatg
     5401 tgattgaaaa aggcttgaaa cagtctagtc gtagtggcag agggcgtggt tcaaatcgtc
     5461 gttcggataa gaaggaagac aagagaaaat caggacgctc aaatgataag cgtaagcatt
     5521 cacaaaaaga caagaagaaa aaaggaaaga aatcttttta caaggaagta gctaagaaag
     5581 gagccaagca tggcaaaggg cgagggaaag gtcgtcgcac aaaataaaaa ggcacgccac
     5641 gactatacaa tcgtagatac gctagaggca gggatggtcc tgactggaac tgaaatcaag
     5701 agtgtacgag ctgctcgaat taatctcaag gatggctttg ctcaagtgaa aaatggagaa
     5761 gtttggctga gcaatgttca tatcgcgcct tacgaagagg gcaatatctg gaaccaggaa
     5821 ccagaacgtc gtcgtaaact cctgctccat aaaaagcaaa ttcaaaaatt ggaacaagag
     5881 accaaaggga caggaatgac cttagttccc cttaaggtct atataaaaga tggctacgct
     5941 aagcttcttt taggacttgc caaagggaag catgactatg acaaacggga gtctatcaaa
     6001 cgtcgtgagc aaaatcgaga tatcgcgcgt gtgatgaaag ctgttaatca gcgataaaaa
     6061 gaggaattga aaatggaaaa attagttgcc tataaacgca tgcctttgtg gaataaacaa
     6121 acaatgcctg aagctgttca gcaaaagcac aatacaaaag ttgggacttg ggggaaaatt
     6181 actgtcttga agggagctct caagtttatt gaattgacag aagaagggga agttctagct
     6241 gaacacctct ttgaagcagg ggcagacaat ccaatggccc aacctcaagc ctggcaccga
     6301 gtggaagctg ccacagatga tgtggaatgg tacttggaat tttattgtaa acctgaggat
     6361 tattttgcta aaaaatacaa taccaatcct gttcattcag aggtcctaga ggccatgcag
     6421 acagtgaaac aagggaaagc tttggatttg ggttgtggtc aggggcgtaa ttctcttttt
     6481 ctagcccagc aagattttga tgtgacggct gtagatcaaa atggactagc tcttgaaatc
     6541 ttgcaaagca ttgtggagca ggaagatttg gacatgcctg ttggccttta cgatatcaat
     6601 tcagctagca ttgaacaaga atatgatttt atcgtttcaa cagttgttct catgtttcta
     6661 caagcggacc gcattccagc tattattcaa aatatgcagg agaaaaccag tgttggcggt
     6721 tacaacctta tcgtttgtgc catggacacg gaggattatc cttgctcggt taacttccca
     6781 ttcaccttta aagaaggaga actggcagac tattacaagg attgggaatt ggttaagtac
     6841 aatgaaaatc caggccattt gcaccgtcgc gatgagaatg gcaatcgtat tcaactacgc
     6901 tttgcgacct tactagctaa gaaaatcaag taaacacaca tgaagattag gaattttcct
     6961 gatctttttt cttttttacg aatgatatag aaaaggaggg aattcatgtt tgttgcgaga
     7021 gatgctaggg gagaattggt aaatgtgtta gaggataaac ttgagaagca agcatacacc
     7081 tgcccagctt gtggaggcca gctccatttg cgtcaaggac caagtgtacg gacgcatttt
     7141 gcccataaat ccttaaaaga ctgtgatttt ttctttgaaa atgaaagtcc agaacacctg
     7201 gccaataagg aatccctcta tcactggttg aaaaaagaga caaaggttca attagagtac
     7261 ccgctttcag aacttaaaca gattgcggat gtatttgtaa atggcaatct agctctagaa
     7321 gttcagtgta gtcccttgcc tcagaaagtc cttaaagagc gaagtgaggg ctatcgtagt
     7381 cagggttacc aagtactgtg gttgctgggt caaaaactgt ggctcaagga gcgtttgact
     7441 cgtctacagc aaggttttct ttatttcagt caaaacatgg gcttttatgt ttgggaatta
     7501 gacaaggaaa aacaagtttt aagactcaaa tacctgattt accaggatct ccgcggtaaa
     7561 ctccattatc aaatcaagga attttcctat ggtcaaggta gtttattgga aatattgcgt
     7621 cttccctata agagacaaaa aatatctcat tttacagttt ctgaggacaa ggacatctgt
     7681 cgctatatcc ggcaacaact ttattatcaa aatctctttt ggatgaaaga acaagcagaa
     7741 gcctatcaaa agggagaaaa tatcctgact tatggactga aagaatggta tccacaaatt
     7801 cgaccaatag tgggcaaatt tttccagatt gaacaagact tgactagcta ttatcagcac
     7861 ttttatacct attaccaaaa aaatcctcaa aatgattggc aaaagcttta tccaccagcc
     7921 ttttatcagc aatatttctt gaaaaatatg gtagaataga aaggatggag gaatctaatg
     7981 gtattacaaa gaaatgaaat aaatgaaaaa gatacatggg atctatcaac gatctaccca
     8041 actgaccagg cttgggaaga agccttaaaa gatttaacag aacaattgga gacagtagcc
     8101 cagtatgaag gccatctctt ggatagtgcg gataacctac tagaaatcac tgaattttct
     8161 cttgaaatgg aacgccagat agagaagctt tacgtttatg ctcatatgaa gaatgaccag
     8221 gatacacgtg aagctaagta tcaagagtac tatgccaagg ccatgacact ctacagccag
     8281 ttagaccaag ccttttcatt ctatgagcct gaatttatgg agattagcga aaagcagtat
     8341 gctgactttt tagaagctca accaaagctg caggtttatc aacactattt tgacaagctc
     8401 ttgcaaggca aggatcacgt tctttcacaa cgtgaagaag aattattggc tggagctgga
     8461 gaaatctttg gttcagcaag tgaaaccttc gctatcttgg acaatgcgga tattgtgttc
     8521 ccttatgtcc tagacgatga tggtaaagaa gttcagctat ctcatgggac ttacacacgt
     8581 ttgatggagt ctaaaaaacg tgaggttcgc cgtggtgcct atcaagctct ttatgcgact
     8641 tacgaacaat tccaacacac ctatgccaaa accttgcaaa ccaatgttaa ggtgcaaaat
     8701 taccgtgcta aagttcgtaa ctacaagagt gctcgtcatg cagccctcgc agcgaatttt
     8761 gttccagaaa gtgtttatga caatttggta gcagcagttc gcaagcattt gccactctta
     8821 catcgctatc ttgagcttcg ttcaaaaatc ttggggattt cagatctcaa gatgtacgat
     8881 gtctacacac cgctttcatc tgttgaatac agttttacct accaagaagc cttgaaaaaa
     8941 gcagaagatg ctttggcagt cttgggtgag gattacttga gccgtgttaa acgtgccttc
     9001 agcgagcgtt ggattgatgt ttacgaaaat caaggcaagc gttcaggtgc ctactctggt
     9061 ggttcttacg ataccaattc ctttatgctt ctcaactggc aggacaatct ggacaatctc
     9121 tttactcttg ttcatgaaac aggtcacagt atgcattcaa gctatactcg tgaaactcag
     9181 ccttatgttt acggggatta ctctatcttt ttggctgaga ttgcctcaac taccaatgaa
     9241 aatatcttga cggagaaatt attggaagaa gtggaagacg acgcaacacg ctttgctatt
     9301 ctcaataact tcctagatgg tttccgtgga acagttttcc gccaaactca atttgctgag
     9361 tttgaacacg ccattcacca agcagatcaa aatggggagg tcttgacaag cgatttccta
     9421 aataaactct acgcagactt gaaccaagag tattatggtt tgagtaagga agacaatcct
     9481 gaaatccaat acgagtgggc tcgcattcca cacttctact ataactacta tgtatatcaa
     9541 tattcaactg gctttgcggc cgcctcagcc ttggctgaaa aaattgtcca tggtagtcaa
     9601 gaagaccgtg accgctatat cgactacctc aaggcaggta agtcggacta tccacttaat
     9661 gtcatgagaa aagctggtgt tgatatggag aaggaagact acctcaacga tgcctttgca
     9721 gtctttgaac gccgtttaaa tgagtttgaa gcccttgttg aaaaattagg attggcataa
     9781 aatggttgaa tcgtatagta agaatgctaa ccataacatg cgtcgtcctg tcgtcaaaga
     9841 agaaattgta gacttgatgc gtcagcgtca aaagcaggtc acaggtttct tgaaagaatt
     9901 ggaagacttt gcccgcaagg aaaatattcc tattattccc catgaaacgg ttgcttattt
     9961 ccgttttctt atggaaacca tgcagcctaa aaatattctg gaaattggga cggctatcgg
    10021 tttttcagct ctcttgatgg ctgaacatgc gccaaatgct aagattacaa ctattgatcg
    10081 taatccagaa atgattggtt ttgccaagga aaattttgcc cagtttgaca gtcgcaagca
    10141 aatcactctc ctagagggag atgcggtgga tgtcttatct acactgacag agtcttatga
    10201 tttcgtattt atggattctg ccaagtctaa atacatcgtc tttctgccag aaatcctcaa
    10261 acatttggaa gttggtggtg tggttgtctt ggatgatatt tttcaaggtg gtgatgttgc
    10321 caaggatatt atggaagtcc gtcgtggtca gcgaaccatt tatcgaggcc ttcaaaaatt
    10381 atttgatgca accttagaca atccagaact caccgcaaca ttagtgcctt taggagatgg
    10441 tattctcatg cttcgtaaaa atgtagcaga tgttcaactg tctgaaagcg aatgattttc
    10501 agaaaaattt aagaaaaaat agtaaaatag atagagtaac acttatctca aaggagtaga
    10561 catgaagaaa aaattattgg caggtgccat cacactatta tcagtagcaa ctttagcagc
    10621 ttgttcgaaa gggtcagaag gagcagacct tatcagcatg aaaggggatg tcatcacaga
    10681 acatcaattt tatgagcaag tgaaaaacaa cccttcagcc caacaagtct tgttaaatat
    10741 gaccatccaa aaagtttttg aaaaacaata tggctcagag cttgatgata aagaggttga
    10801 tgatactatt gccgaagaaa aaaaacaata tggcgaaaac taccaacgtg tcttgtcaca
    10861 agcaggtatg actcttgaaa cacgtaaagc tcaaattcgt acaagtaaat tagttgagtt
    10921 ggcagttaag aaggtagcag aagctgaatt gacagatgaa gcctataaga aagcctttga
    10981 tgagtacact ccagatgtaa cggctcaaat catccgtctt aataatgaag ataaggccaa
    11041 agaagttctc gaaaaagcca aggcagaagg tgctgatttt gctcaattag ccaaagataa
    11101 ttcaactgat gaaaaaacaa aagaaaatgg tggagaaatt acctttgatt ctgcttcaac
    11161 agaagtacct gagcaagtca aaaaagccgc tttcgcttta gatgtggatg gtgtttctga
    11221 tgtgattaca gcaactggca cacaagccta cagtagccaa tattacattg taaaactcac
    11281 taagaaaaca gaaaaatcat ctaatattga tgactacaaa gaaaaattaa aaactgttat
    11341 cttgactcaa aaacaaaatg attcaacatt tgttcaaagc attatcggaa aagaattgca
    11401 agcagccaat atcaaggtta aggaccaagc cttccaaaat atctttaccc aatatatcgg
    11461 tggtggagat tcaagctcaa gcagtagtac atcaaacgaa tagtccaaat caatgagtca
    11521 gggaaaaaac tctacttcag gaaaaaatga agcaaacatt cccacaataa aacgcgtagt
    11581 acaaggtttg tactgacccc caaaagttag acaaataatt tatccgaagg atttagttct
    11641 gtattgcaca gggctaagtc cttttagttt taccttaatt ctcttgttgt tgtaataatc
    11701 aatatagtct ataatggctt gttccaattg attaagtgat ttaaatgttt tctcatagcc
    11761 ataaaacatt tcggatttta aaataccaaa gaaagattcc atcctaccgt tgtcttggct
    11821 gtttcccttg cgtgacatag atgcttgaat tcccttactc tctaggaacc gatgataaga
    11881 atcgtgttgg tattgccagt cttggtcact atggagaatc gtattctcgt agtgcttctc
    11941 tttgaatgcc tgttccaaca ttaacgatca atcaatttaa tcatgtacct aatattagaa
    12001 ttgtttatct caaatttatt tgaaagcttc tctaagctat atccttgttt tctaagttca
    12061 tagatctgaa ctttatcatc ataagttaat ttcataataa aaacactcca aaagttagat
    12121 tttttctgtc taacttttgg ggtgcagttc atttaacacc tgataatatg cgtttttttt
    12181 attttaaaga ctttttgacc agcctcattt tttaacttga tactcagtga aaagcaaaga
    12241 ttaaactagg aagctagctg taggctgctc aaagaacagc tttgaggttg cagataaaac
    12301 ttgtgaggta accaacatat ataatgtgaa gctgacgtgg tttgaataga ttttagaagg
    12361 gtatgagtct ggaagtttta atggataatg caagattcca tagaatgggt aagctagagt
    12421 tcttatgtga agagtttggg cataaacttt taccttttcc tccctactca tcttagtata
    12481 gaaaagtgaa tctaaaatag tacataactg cttctaaaac attcttataa attgatttaa
    12541 attctcaaat catattattc agttcttatt tcattttgct ctacaatcct gttgagaaga
    12601 cacgtgttca tatcaaaaaa ggtattggca agttgcaata cctttttacg aggctctttt
    12661 atcttatttt tgtttcaact gactatatct cctatggttc tagttcagaa ggctaggcta
    12721 taattatgat tgataagaag tatcattcca agtattgaga gtgaatgttt caaaatcatg
    12781 ggtttctata atggtcaggc tggcatttgc tagaccgcca tctttacgaa gaagtggttc
    12841 tttatagcct aggagagtac gaagactggc agtaagattg gcgccgtgtc cgacaattag
    12901 aatacgttca gctggactat cttttaatga tttgataaat tggatggtcc gttgagttgt
    12961 actatagagg gattcggctc cgaacattcg agtgtcaaat tgagcaagat ttgaacgaaa
    13021 agcctggatt tgttgcgggt aaatagcttc caaggttgca attttcaaac cttctaactt
    13081 cccaagttgc cattcacgga gattaggaac gatttctaaa gaacaggggg tatagagttg
    13141 actttggata atctcagcag atttgaccgc tcgaggtaaa tcacttgaat aaatctgatc
    13201 aaaaggaatt tccttgagat actgaccaag tcgttttagg gtttcaatgg attcaggaag
    13261 aagaggagaa tcaccactag caccttgaaa acgaccttct tggttccaga gggtacgacc
    13321 gtggcggaca aagtagagtt tcattacttg atgtcctcca aaatatctac aaagtctgcc
    13381 tttacaaagc tagccaagtc ttgtggcgcg acgataatgc tgtgtccgac ttcgcctgca
    13441 gagacaatca tttgatccaa atctagagca attttatcga taaaaatggg ataattgtgt
    13501 ttctgacgaa ttccgacagg attattggct ccatgaatgt aaccagttgt tttttctaag
    13561 tccttttgtg gaatcatgct cactttttta ttgccagaaa ttttagctag tttcttttca
    13621 gacaagtgct gagtgatagg gacaattccg ataatcggtc cggtcttgtc tcccaaaagc
    13681 gccaaggttt tgaaaatctg atctcgttca taaccttgag gaagctctcc ttctagggca
    13741 ttgatttgaa tcccctgatg agggatagct gctttagata ggatttgttc caccaatgtt
    13801 tttttgattt taactttttt tgccattatt tatatttatc ctccaattga ctcatccaaa
    13861 taccaagcca gattcccagc gcaaagaaga aggcgatgat gacataaccg acaagtgaaa
    13921 gtcctgtgta ttggatactt tcagcgtttc ctgcatttgg aattaagatc aaaagggtac
    13981 ttgataggac gataccgatg atgaaatgat agacacgtga gtggtagttg tttaaggcat
    14041 aatccatcaa ttttgaaaaa acgatgagag ttgcacctgc accaattcca atcggaaaga
    14101 aggttcccaa gaaatcaaaa gttttaaaac cagtcaacat aggagcatag agtcccaaaa
    14161 tcaaaagtaa atttgatggg ctgaggccag gaaccaagac gccaagggcc aatagtgcgc
    14221 ctgctaggac gaagttaaga aagctggcgc ttaaggttcc aacgacaaaa tttaaggcat
    14281 agagtcctaa tccagaaatg ataaaggttg tccataacca agctaaatca atcttgtctc
    14341 ggtcagattc tcgagttgat tctttgagga ggctaggaac tgtaccgata atagctcccg
    14401 caaagctcca taatacaaaa acctgataat tttcaagcag gtattcaatc gggtaggaaa
    14461 ataagccgat tcccagaagc ataccgatgg caactggaat aaagtacaaa acattttctt
    14521 taaagtcttt aaagggatgg gccagaaagc caatcattcg ttcatagatt cctaagattg
    14581 ctgctagaac ccctccggaa attcccggta ggataaatcc aagagcaatt acaatccctt
    14641 taataacgcg tgctaaccat gagagcatat atttcctcca actatttcta tttcaaaaaa
    14701 tccttactat attgtatcac aatcagacac aaaaagaaaa agcaaatgat aaacaaatgc
    14761 ttttaaggtt ttaaaaaaag ttttcgaaag gtttcttctt tattttttaa gggagagata
    14821 acgttgatat ctaaatcgtg gtcaaagccg gcaatttttc ctttagatgt gtattggtga
    14881 atatcataat ctaaatcagt tttaggactg ctctccaaaa atcctgagtc tgagccgtag
    14941 gacggaatcc aaacagaggt aaacttgcct gtatcaatac tgtgttcttc catgaagtag
    15001 acaccaacgt agatgccgat gtttttagca cctagtgatg ctagttttgc tcgaaagttt
    15061 tcgacacctt cgttcatatt agacatggtt ttgtcttcca cgtcaagcca atagtaacta
    15121 gggctgtaag gagaggcagc attgtagaaa acttcggcag ccttttccat ttcttggaca
    15181 ctttttccag ctacataagc gtagacagca actgggacat tccgcttttg aagttcagtg
    15241 atatgactct tataggtctt gtctattcca ttgataaatg aagcatcatt ttcttttgtt
    15301 gtttgagcac cactgtgaac acgaacaata gcacctgaaa tattttgtga gagggcatcg
    15361 tagttgattt cctcaggacg ctgccagcca gagaggtcaa taatcggttt gtctaagtgt
    15421 ttcaaagcct gtgcttcaat ctgtgctata ttggattttg ttttaaacga ttggctgtca
    15481 ttaagtgggc gattgatgat taaaatgaac atcataatcc caaaaaaact aaataaaata
    15541 agtggatgaa tttgttttct catatcttat aattctaccc taaaaatcaa aaaaaatcaa
    15601 aaaaatgggt taaggaagag actttagagc attttttcat tcaagagtgc ggaatgattt
    15661 gaaatatggt ataataaaag ggaatttcta cagaaaagag aagattatgt caaattttgc
    15721 cattatttta gcagcgggta aagggactcg catgaaatct gatttgccaa aagttttgca
    15781 caaggttgcg ggtatttcta tgttggaaca tgttttccgt agtgtgggag ctatccaacc
    15841 tgaaaagaca gtaacagttg taggacacaa ggcagaattg gttgaggagg tcttggctga
    15901 acagacagaa tttgtgactc aatctgaaca gttgggaact ggtcatgcag ttatgatgac
    15961 agagcctatc ttagaaggtt tgtcaggaca caccttggtc attgcaggag atactccttt
    16021 aatcactggt gaaagcttga aaaacttgat tgatttccat atcaatcata aaaatgtggc
    16081 cactatcttg actgctgaaa cggataatcc ttttggctat ggacgaattg ttcgtaatga
    16141 caatgctgag gttcttcgta ttgttgagca gaaggatgct acagattttg aaaagcaaat
    16201 caaggaaatc aacactggaa catacgtctt tgacaacgag cgtttgtttg aggctttgaa
    16261 aaatatcaat accaataacg ctcaaggcga atactatatt acagacgtca ttggtatttt
    16321 ccgtgaaact ggtgaaaaag ttggcgctta tactttgaaa gattttgatg aaagtcttgg
    16381 ggtaaatgac cgtgtggcgc ttgcgacagc tgagtcagtt atgcgtcgtc gcatcaatca
    16441 taaacacatg gtcaacggtg ttagctttgt caatccagaa gcaacttata tcgatattga
    16501 tgttgagatt gctccggaag ttcaaatcga agccaatgtt atcttgaaag ggcaaacgaa
    16561 aattggtgct gagactgttt tgacaaacgg tacttatgta gtggacagca ctatcggagc
    16621 aggagcggtc attaccaatt ctatgattga ggaaagtagt gttgcagacg gtgtgacagt
    16681 cggtccttat gctcacattc gtccaaattc aagtctgggt gcccaagttc atattggtaa
    16741 ctttgttgag gtgaaaggat cttcaatcgg tgagaatacc aaggctggtc atttgactta
    16801 tatcggaaac tgtgaagtgg gaagcaacgt taatttcggt gctggaacta ttacagtcaa
    16861 ctatgacggc aaaaacaaat acaagacagt cattggagac aatgtctttg ttggttcaaa
    16921 ttcaaccatt attgcaccag tagaacttgg tgacaattcc ctcgttggtg ctggttcaac
    16981 tattactaaa gacgtgccag cagatgctat tgctattggt cgcggtcgtc agatcaataa
    17041 agacgaatat gcaacacgtc ttcctcatca tcctaagaac cagtaggagc ctatcatgga
    17101 gtttgaagaa aaaacgctta gccgaaaaga aatctatcaa ggaccaatat ttaaactggt
    17161 ccaagatcag gttgaattac cagaaggcaa gggaactgcc caacgggatt tgattttcca
    17221 caatggggct gtctgtgttt tagcagtaac ggatgaacaa aaacttatct tggtcaagca
    17281 gtaccgcaaa gctatcgagg cagtctctta cgaaattcca gccggaaaat tggaggtagg
    17341 agaaaacaca gcccctgtcg cagctgccct tcgtgaatta gaggaagaaa cagcctatac
    17401 agggaaatta gaactcttgt acgattttta ttcagctatt ggcttttgta atgagaagtt
    17461 aaaactatat ttagcaagcg atttgacaaa agtggaaaat ccgcgtccgc aggatgagga
    17521 tgaaaccttg gaagtccttg aagtgagctt agaagaagcg aaagaattaa tccaatcagg
    17581 tcatatctgt gatgccaaga caattatggc tgttcagtat tgggagttgc agaaaaaata
    17641 gaggaggtca gtatgggtaa atctttatta acggatgaaa tgattgaaag agctaataga
    17701 ggcgaaaaaa tttcaggtcc tcctttgcta gatgataatg aggagactaa gattttacca
    17761 acctcttctt cccgttttgg ttatgccaat cctaaggatc atggttttag ccaggaaacc
    17821 ttgaaaattc aggtcgaacc atctattcat aaaagccgtc gcattgaaaa taccaagaga
    17881 aatgtcttca attctaagtt gaataaaatc ttattcgcgg tcatctttct cttgattttg
    17941 cttgttttag caatgaaact tttgtaatag aaaaggaatt gaaatgaaaa taggaattat
    18001 tgctgctatg ccagaagaac tggcttatct ggtccagcat ttagataata cccaggagca
    18061 agttgttttg gggaatacct atcatacagg aaccattgct tctcatgaag tcgttcttgt
    18121 agaaagtgga attggtaagg tcatgtctgc tatgagtgtg gcgattttgg ctgatcattt
    18181 ccaggtggat gcccttatta atacgggttc agctggggca gtagcagaag gtatcgctgt
    18241 tggggatgtc gtgattgctg acaaattagc ctatcatgac gtggatgtca cagcttttgg
    18301 ctatgcttat ggacaaatgg cgcaacaacc gctttatttc gaatcagaca aaacctttgt
    18361 tgctcaaatc caagagagtt tatctcaatt ggaccaaaac tggcatcttg gtttgattgc
    18421 tacaggagat agttttgttg caggaaatga caagatagaa gcgattaagt cccatttccc
    18481 agaagtttta gccgtggaga tggagggggc agctattgct caagcagcgc atgccctcaa
    18541 tctcccagtc ttagtcatca gagctatgag tgacaatgcc aaccatgaag caaacatctt
    18601 ttttgatgag tttattatcg aagctggacg tcgctctgcc caagtcttgt tgaccttttt
    18661 gaaggcttta gattaagcgg aaatttgaca gtttttctag cttatgataa gatttaagta
    18721 aagaaaagct agaaaacgtt tcagaggata ttatgagtat tgaaatgacc gtcagtgaga
    18781 ttgcagaggt cttaggatta tctcgccaag caatcaataa ccgtgtcaaa gaattaccag
    18841 aagaagacac agataaaaat gacaaagggg taacagttgt taccagaagt ggcttgatta
    18901 agctagaaga aatctataaa aaaacgattt ttgaagatga gcctgtcagt gaagatgtca
    18961 aacaacgtga actgatggag attctagtgg atgagaagaa tgcagaaatt cttcgtcttt
    19021 atgaacaatt aaaagccaag gatcgtcagt tatcagaaaa agacgagcag atgcgtatca
    19081 aagaccgtca gattgctgag aaagacaaac aattagatca gcaacaacaa ttgacccttc
    19141 aagctatgaa ggatcaagaa aatcttaagc tagagctgga ccaagcaaaa gaagaagtcc
    19201 aatccactaa gaaaggcttt tttgctcgtt tatttggagg ataatcaagg agctgtttag
    19261 gttaaatgct aacctgatgg cttcttttgt ttgtgaatag tatagttgat tagaacagag
    19321 acagtagagg agaggtacag aatggaacga ttagaagatt acattgcttt tgatttagaa
    19381 tttaatcagc acgaaggaca aacacacttg attcaagtat cggcagtgcg ttttagagat
    19441 ggtcgggaaa tcgatgccta tgattcctat gttcatacca gcgttcctct aaaaagcttt
    19501 atcaatggtt tgaccgggat tacagctgag accttaaaag atgctcctcc agttgagaaa
    19561 gtcttagaag aattccaaga gtttgtgggt tctttgctga tgataggcta caatgctgct
    19621 aaaagtgatt tacctatttt agcagagcat ggtttagact atagccaaca gtacaaggtg
    19681 gatttgtatg atgaagcttt tgaacgtcgg agttcagatt tacatggtat tgccaatctc
    19741 aaattgcaaa ctgttgcctc atttcttgga tttcaaggtc agtctcataa tagtttagag
    19801 gatgctcgga tgacggcgcg tgtttacgaa tccttcttag agtcggatca agctagggaa
    19861 ttgttagaga cagaaagtag cttatcaaac aatccttttg gtggcttgaa cttgtctcaa
    19921 ttatttgact aggagtgcct atgaaacctg aaaaacctaa aaaattgggt cttaaacaga
    19981 tttacctcaa tcttgataaa atcctctttc tatttttctt gatttttatg atagtggagt
    20041 atttgtgggt accattcaat tcatggttgg ctagcttctt attagatcag acaggttatc
    20101 tttttatttc ctataacaat gtcttagcca tccttactca ttctccattg attagtctag
    20161 cttttttagc cttgattgta attaaccttc tggttgctta ttttcaaata ggactcctct
    20221 ttattggtgc tcgtcatctc ctctataatg aaaagcgaag gctaattgag tatatccgta
    20281 aggttttcca tgaaagtttt ggatttatga aaaagctaac ttgcgctaaa gccttgttta
    20341 tctttttcta tatagctatg ctttttcctt ttatacggaa aatgctgaag atttattatc
    20401 ttaataaaat cgtcattcca gagtttatcc aagcttattt agaagataaa tattggatgt
    20461 ggtggctgag catcctactt ctatctctta tctttctcta tgtctctgtc agattgatgt
    20521 ttgcccttcc gaagattgta tatgatcagc tgactgttcg agaagcagtg atgtttagct
    20581 tggagaaaac caagaagaga gttacttttt atgcttggaa tttattttac atcttgctca
    20641 aagcacattt attattttat cttcctttga ttccttcatt attggctcaa actttggtag
    20701 atgatatcac tcagagagag tctctgattc ttggtatttt gaattttgtc gtgattaaaa
    20761 atctctatta tatggctctg acttattttt tggttaaatt tgtttcattt ttgacaggaa
    20821 aggagctgga tatgcttcct aggagagaaa aagatcacat cgtgcgatgg ggtgtcatga
    20881 cttgtgccag tcttttcttt gccttagaag gttatattta tctggaggct cccatggttc
    20941 atctacctca acttatttct caccgagggg tttccaatgc aaatgggatt caaaatacag
    21001 tagagtcctt ggaaactaca gcacaactca aaccagactt ggtggagacg gacgtgcagg
    21061 aaacaaaaga tgggcagttt gtcatgatgc atgatgctaa cttgaaaaat ctagcaggta
    21121 tcaataaaag tcctcaagac ttaaacttgg aggagcttaa agggattgat atttttgaaa
    21181 atggctacca gactaaaatt tcaagctttg aagattatct cagtcgagcc aacgaacttg
    21241 gtcaaaaatt actaattgaa attaaaacca gtaaaaaaga tagtccagat atgatgaacc
    21301 gctttttagc ccgttatgct gcaaagctca agatttatgg acatcaaatc cagtctttag
    21361 actaccatgt tgtcgaaaaa gtaagacagt atgatgccga actaccagtt tatttcatca
    21421 tgccctacaa ttctgtcttt cctaaaacaa gagcgacagg atatactatg gagtactcaa
    21481 ccttggatga atattttgta agcaaactat ggacaacgga tcagaaactt tatgtctgga
    21541 ctgtcaatga ttcagaagct atcagcaaat ctcttcactt aggagtagat ggagtgatta
    21601 cagatgattt ggaaaaagtt cagcgggaaa tagaagtagc ccaagaagat ccagaatata
    21661 cggatttgct cttgaaaaaa gcattggaat tctttgaatt ttagtaataa aaaagaggaa
    21721 cggttgttcc tcccatgata ggtaagtatt cttgtgaatg attgcttttt tgtggttgca
    21781 atccgtttac gagaattgtt tgtattgttc ttgtttcaat ttactttata gtgctttgaa
    21841 gttggaatgc tacactataa cttct
//
LOCUS       DAVHTH010000034        21666 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.034, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000034 DAVHTH010000000
VERSION     DAVHTH010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21666)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21666)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21666
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.034"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            <1..256
                     /locus_tag="VVR63_001355"
     CDS             <1..256
                     /locus_tag="VVR63_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU6129368.1"
                     /translation="TRKEIVNWHIKASQYYLEPLYNLLRERLLTQSLLHADETSYRVL
                     ESDSQLTYYWTFLSGKAEKQGITLYHHVLIDLFISYFNPL"
     gene            complement(453..1373)
                     /gene="cysK"
                     /locus_tag="VVR63_001356"
     CDS             complement(453..1373)
                     /gene="cysK"
                     /locus_tag="VVR63_001356"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HEU6129369.1"
                     /translation="MSIYNNITELIGQTPIVKLNNIVPEGAADVYIKLEAFNPGSSVK
                     DRIALSMIEKAEQDGILKPGSTIVEATSGNTGIGLSWVGAAKGYKVVIVMPETMSVER
                     RKIIQAYGAELVLTPGSEGMKGAIAKAQEIAAERDGFLPLQFDNPANPEVHERTTGAE
                     ILAAFGKDGLDAFVAGVGTGGTISGVSHALKSENSNIQVFAVEADESAILSGEKPGPH
                     KIQGISAGFIPDTLDTKAYDGIVRVTSDDALALGREIGGKEGFLVGISSAAAIYGAIE
                     VAKKLGTGKKVLALAPDNGERYLSTALYEL"
     gene            complement(1658..2293)
                     /locus_tag="VVR63_001357"
     CDS             complement(1658..2293)
                     /locus_tag="VVR63_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HEU6129370.1"
                     /translation="MEFRTIKEDGQVQEEIKKSRFICHAKRVYSEEEARDFITAIKKE
                     HYKATHNCSAFIIGERSEIKRTSDDGEPSGTAGVPMLGVLENHNLTNVCVVVTRYFGG
                     IKLGAGGLIRAYAGSVALAVKEIGIIEIKEQAGIAIQMSYAQYQEYSNFLKEHDLMEL
                     DTNFTDQVDTMIYVDKEEKETIKAALVEFFNGKVTLTDQGLREVEVPVNLV"
     gene            2349..3647
                     /locus_tag="VVR63_001358"
     CDS             2349..3647
                     /locus_tag="VVR63_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU6129371.1"
                     /translation="MKVNLDYLGRLFTENELTEEERQLAEKLPAMRKEKGKLFCQRCN
                     STILEEWYLPIGAYYCRECLLMKRVRSDQTLYYFPQEDFPKQDVLKWRGQLTPFQEKV
                     SEGLLQAVDKQKPTLVHAVTGAGKTEMIYQVVAKVINAGGAVCLASPRIDVCLELYKR
                     LQQDFSCGIALLHGESEPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPTL
                     YHAVKNSVKENGLRIFLTATSTNELDKKVRLGELKRLNLPRRFHGNPLIIPKPIWLSD
                     FNRYLDKNRLSPKLKSYIEKQRKTAYPLLIFASEIKKGEQLEEILQEQFPNEKIGFVS
                     SVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVVEANHRLFTKSSLIQIGG
                     RVGRSMDRPTGDLLFFHDGLNASIKKAIKEIQMMNKEAGL"
     gene            3644..4306
                     /locus_tag="VVR63_001359"
     CDS             3644..4306
                     /locus_tag="VVR63_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HEU6129372.1"
                     /translation="MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEEN
                     CPNCMKTELSTKCQDCQLWCKEGVGVSHRAIFTYNQAMKDFFSRYKFDGDFLLRKVFA
                     SFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
                     KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSL
                     VR"
     gene            4386..4934
                     /gene="raiA"
                     /locus_tag="VVR63_001360"
     CDS             4386..4934
                     /gene="raiA"
                     /locus_tag="VVR63_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000599099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HEU6129373.1"
                     /translation="MIKYSIRGENLEVTEAIRDYVVSKLEKIEKYFQPEQELDARINL
                     KVYREKTAKVEVTIPLGSITLRAEDVSQDMYGSIDLVTDKIERQIRKNKTKIERKNKN
                     KVATGQLFTDALVEDSNVVQSKVVRSKQIDLKPMDLEEAILQMDLLGHDFFIYVDVED
                     QTTNVIYRREDGEIGLLEVKES"
     gene            5070..7043
                     /locus_tag="VVR63_001361"
     CDS             5070..7043
                     /locus_tag="VVR63_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HEU6129374.1"
                     /translation="MKKFYVSPIFPILVGLIAFGVLSTFIIFVNNNLLTVLILFLFVG
                     GYVFLFKKLRVHYTRSDVEQIQYVNHQAEESLTSLLEQMPVGVMKLNLSSGEVEWFNP
                     YAELILTKEDGDFDLEAVQTIIKASVGNPSTYAKLGEKRYAVHMDASSGVLYFVDVSR
                     EQAITDELVTSRPVIGIVSVDNYDDLEDATSESDISQINSFVANFISEFSEKYMMFSR
                     RVSMDRFYLFTDYTVLEGLMNDKFSVIDAFREESKQRQLPLTLSMGFSYGDGNHDEIG
                     KVALLNLNLAEVRGGDQVVVKENDETKNPVYFGGGSAASIKRTRTRTRAMMTAISDKI
                     RSVDHVFVVGHKNLDMDALGSAVGMQLFASNVIENSYALYDEEQMSPDIERAVSFIEK
                     EGVTKLLSVKDAMGMVTNRSLLILVDHSKTALTLSKEFYDLFTQTIVIDHHRRDQDFP
                     DNAVITYIESGASSASELVTELIQFQNSKKNRLSRMQASVLMAGMMLDTKNFTSRVTS
                     RTFDVASYLRTRGSDSIAIQEIAATDFEEYREVNELILQGCKLGSDVLIAEAKDTKCY
                     DTVVISKAADAMLAMSGIEASFVLAKNTQGFISISARSRSKLNVQRIMEELGGGGHFN
                     LAAAQIKDVTLSEAGEKLTEIVLNEIKEKEKEE"
     gene            7040..7492
                     /gene="rplI"
                     /locus_tag="VVR63_001362"
     CDS             7040..7492
                     /gene="rplI"
                     /locus_tag="VVR63_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HEU6129375.1"
                     /translation="MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATAQAV
                     GELRGKQKSEEKAHAEMIAEGKAIKAQLEAEETVVEFVEKVGPDGRTFGSITNKKIAE
                     ELQKQFGIKIDKRHIQVQAPIRAVGLIDVPVKIYQDITSVINLRVKEG"
     gene            7536..8888
                     /gene="dnaB"
                     /locus_tag="VVR63_001363"
     CDS             7536..8888
                     /gene="dnaB"
                     /locus_tag="VVR63_001363"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HEU6129376.1"
                     /translation="MAEVEELRVQPQDILAEQSVLGAIFIDESKLVFVREYIESRDFF
                     KYAHRLIFQAMVDLSDRGDAIDATTVRTILDNQGDLQNIGGLSYLVEIVNSVPTSANA
                     EYYAKIVAEKAMLRRLIAKLTESVNQAYEASQPADEIIAQAEKGLIDVSENANRSGFK
                     NIRDVLNLNFGNLEARSQQTTDITGIATGYRDLDHMTTGLHEEELIILAARPAVGKTA
                     FALNIAQNIGTKLDKTVAIFSLEMGAESLVDRMLAAEGLVESHSIRTGQLTDEEWQKY
                     TIAQGNLANASIYIDDTPGIRITEIRSRSRKLAQETGNLGLILIDYLQLITGTGRENR
                     QQEVSEISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYERGGEEEEGIPNNKVEVIIEKNRSGARGTVELIFQKEYNKFSSISKREA
                     "
     gene            8890..9156
                     /locus_tag="VVR63_001364"
     CDS             8890..9156
                     /locus_tag="VVR63_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001278167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6129377.1"
                     /translation="MSDAFTDVAKMKKIKEEIKAHEGQVVEMTLENGRKRQKNRLGKL
                     IEVYPSLFIVEFGDVEGDKQVNVYVESFTYSDILTEKNLIHYLD"
     gene            9245..10591
                     /gene="cbpD"
                     /locus_tag="VVR63_001365"
     CDS             9245..10591
                     /gene="cbpD"
                     /locus_tag="VVR63_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase CbpD"
                     /protein_id="HEU6129378.1"
                     /translation="MKILPFIARGTSYYLKMSVKKLVPFLVVGLMLAAGDSVYAYSRG
                     NGSIARGDDYPAYYKNGSQEIDQWRMYSRQCTSFVAFRLSNVNGFEIPAAYGNANEWG
                     HRARREGYRVDNTPTIGSITWSTAGTYGHVAWVSNVMGDQIEIEEYNYGYTESYNKRI
                     IKANTMTGFIHFKDLDGGSVGNSQSSTSTGGTHYFKTKSAIKTEPLVSATVIDYYYPG
                     EKVHYDQILEKDGYKWLSYTAYNGSYRYVQLEAVNKNPLGNSVLSSTGGTHYFKTKSA
                     IKTEPLVSATVIDYYYPGEKVHYDQILEKDGYKWLSYTAYNGSRRYIQLEGVTSSQNY
                     QNQSGNISSYGSNNSSTVGWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGEMQT
                     GWLKENGSWYYLGSSGAMKTGWYQVSGKWYYSYSSGALAVNTTVDGYRVNSDGERV"
     regulatory      10674..10776
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            10847..11137
                     /locus_tag="VVR63_001366"
     CDS             10847..11137
                     /locus_tag="VVR63_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine-binding protein"
                     /protein_id="HEU6129379.1"
                     /translation="MKASIALQVLPLVQGIDRIAVIDQVIAYLQTQEVPMVVTPFETV
                     LEGEFDELMRILKEALEVAGQEADNVFANVKINVGEILSIDEKLEKYTETTH"
     gene            11100..11858
                     /locus_tag="VVR63_001367"
     CDS             11100..11858
                     /locus_tag="VVR63_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009013602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6129380.1"
                     /translation="MRNLRSILRRHISLLGFLGVLSIWQLAGFLKLLPKFILPTPLEI
                     LQPFVRDREFLWHHSWATLRVALLGLILGVLIACLMAVLMDSLTWLNDLIYPMMVVIQ
                     TIPTIAIAPILVLWLGYGILPKIVLIILTTTFPIIVSILDGFRHCDKDMLTLFSLMRA
                     KPWQILWHFKIPVSLPYFYAGLRVSVSYAFITTVVSEWLGGFEGLGVYMIQSKKLFQY
                     DTMFAIIILVSIISLLGMKLVDISEKYVIKWKRS"
     gene            11897..12904
                     /locus_tag="VVR63_001368"
     CDS             11897..12904
                     /locus_tag="VVR63_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU6129381.1"
                     /translation="MKKTWKVFLTLVTALVAVVLVACGQGTASKDNKEAELKKVDFIL
                     DWTPNTNHTGLYVAKEKGYFKEAGVDVDLKLPPEESSSDLVINGKAPFAVYFQDYMAK
                     KLEKGAGITAVAAIVEHNTSGIISRKSDNVSSPKDLVGKKYGTWNDPTELAMLKTLVE
                     SQGGDFEKVEKVPNNDSNSITPIANGVFDTAWIYYGWDGILAKSQGVDANFMYLKDYV
                     KEFDYYSPVIIANNDYLKDNKEEARKVIQAIKKGYQYAMEHPEEAADILIKNAPELKE
                     KRDFVIESQKYLSKEYASDKEKWGQFDAARWNAFYKWDKENGILKEDLTDKGFTNEFV
                     K"
     gene            12904..13632
                     /locus_tag="VVR63_001369"
     CDS             12904..13632
                     /locus_tag="VVR63_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6129382.1"
                     /translation="MTEIRLEHVSYAYGQERILEDINLQVTSGEVVSILGPSGVGKTT
                     LFNLIAGILEVQSGRIVLDGEENPKGRVSYMLQKDLLLEHKTVLGNIILPLLIQKVDK
                     AEAISRADKILATFQLTAVRDKYPHELSGGMRQRVALLRTYLFGHKLFLLDEAFSALD
                     EMTKMELHAWYLEIHKQLQLTTLIITHSIEEALNLSDRIYILKNRPGQIVSEIKLDWS
                     EDEDKEVQKIAYKRQILAELGLDK"
     gene            13751..14209
                     /locus_tag="VVR63_001370"
     CDS             13751..14209
                     /locus_tag="VVR63_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HEU6129383.1"
                     /translation="MRFKNTSDHIEAYIKAILDQSGIVELQRSQLADTFQVVPSQINY
                     VIKTRFTESRGYLVESKRGGGGYIRIGRIEFSSHHEMLRELLYSIGERVSQEIYEDIL
                     QLLVEQELMTKQEMNLLESVALDRVLGEEAPVVRANMLRQIIQEVDRKGK"
     gene            14211..16643
                     /locus_tag="VVR63_001371"
     CDS             14211..16643
                     /locus_tag="VVR63_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEU6129384.1"
                     /translation="MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAG
                     ATLNDYPYEMDRLEEVALELTETDYSQDETFTELPFSRRLQVLFDEAEYVASVVHAKV
                     LGTEHVFYAILHDGNALATRILERAGFSYEDKKDQVKIAALRRNLEERAGWTREDLKA
                     LRQRHRTVADKQNSMANMMGMPQTPSGGLEDYTHDLTEQARSGKLEPVIGRDKEISRM
                     IQILSRKTKNNPVLVGDAGVGKTALALGLAQRIASGDVPAEMAKMRVLELDLMNVVAG
                     TRFRGDFEERMNNIIKDIEEDGQVILFIDELHTIMGSGSGIDSTLDAANILKPALARG
                     TLRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSVADSMTILQGLKATYEKHHRVQ
                     ITDEAVETAVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKAKHVKADDSDLSPADKAL
                     MDGKWKQAAQLIAKEEEVPVYKDLVTESDILTTLSRLSGIPVQKLTQTDAKKYLNLEA
                     ELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAKALAEVL
                     FDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVE
                     KAHPDIFNVLLQVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDI
                     RFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSSDHMQEVVKIMVKPLVASLAE
                     KGIDLKLQASALKLLANQGYDPEMGARPLRRTLQTEVEDKLAELLLKGDLVAGSILKI
                     GVKAGQLKFDIA"
     gene            16964..17617
                     /gene="rr06"
                     /locus_tag="VVR63_001372"
     CDS             16964..17617
                     /gene="rr06"
                     /locus_tag="VVR63_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RR06"
                     /protein_id="HEU6129385.1"
                     /translation="MNILVADDEEMIREGIAAFLTEEGYHVIMAKDGQEVLEKFQDLP
                     IHLMVLDLMMPRKSGFEVLKEINQKHDIPVIVLSALGDETTQSQVFDLYADDHVTKPF
                     SLVLLVKRIKALIRRYYVIEDIWRYQDVTVDFTSYKAHYKNEEIDLKPKELLVLKCLI
                     QHKNQVLSREQILEEISKDVADLPCDRVVDVYIRTLRKKLALDCIVTVKNVGYKISL"
     gene            17614..18945
                     /gene="hk06"
                     /locus_tag="VVR63_001373"
     CDS             17614..18945
                     /gene="hk06"
                     /locus_tag="VVR63_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     HK06"
                     /protein_id="HEU6129386.1"
                     /translation="MIKNPKLLTKSFLRSFAILGGVGLVIHIAIYLTFPFYYIQLEGE
                     KFNESARVFTEYLKTKTSDEIPSLLQSYSKSLTISAHLKRDIVDKRLPLVHDLDIKDG
                     KLSNYIVMLDMSVSTADGKQVTVQFVHGVDVYKEAKNILLLYLPYTFLVTIAFSFVFS
                     YFYTKRLLNPLFYISEVTSKMQDLDDNIRFDESRKDEVGEVGKQINGMYEHLLKVIHE
                     LESRNEQIVKLQNQKVSFVRGASHELKTPLASLRIILENMQHNIGDYKDHPKYIAKSI
                     NKIDQMSHLLEEVLESSKFQEWTECRETLTVKPVLVDILSRYQELAHSIGVTIENQLT
                     DATRVVMSLRALDKVLTNLISNAIKYSDKNGRVIISEQDGYLSIKNTCAPLSDQELEH
                     LFDIFYHSQIVTDKDESSGLGLYIVSNILESYQMDYSFLPYEHGMEFKISL"
     gene            19040..19567
                     /locus_tag="VVR63_001374"
     CDS             19040..19567
                     /locus_tag="VVR63_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HEU6129387.1"
                     /translation="MVLAIILVTFLIRLIFLKRSIENEKRILSNGGKEFGVENTKRLT
                     LAHIVFYLSCLVEAMVHKTMFDGMGMVGLVLLIFSMLMLMLVIHLLGDIWTVKLMLVN
                     NHKYVDHILFRTVKHPNYFLNILPELIGLTLLSHAYMTFVLVFPVYAVILYRRIAEEE
                     KLLHEVIIPNGSIKR"
     gene            19646..>21666
                     /gene="pspC"
                     /locus_tag="VVR63_001375"
     CDS             19646..>21666
                     /gene="pspC"
                     /locus_tag="VVR63_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal surface protein PspC,
                     choline-binding form"
                     /protein_id="HEU6129388.1"
                     /translation="MFASKNERKVHYSIRKFSIGVASVAVASLFMGSVVHATEKEVTT
                     QVATSSNKANKSQTEHMKAAKQVDEYIKKKLQLDRRKHTQNVGLLTKLGVIKTEYLHG
                     LSVSKKKSEAELPSEIKAKLDAAFEQFKKDTLPTEPGKKVAEAEKKVEEAKKKAEDQK
                     EKDLRNYPTNTYKTLELDIAESDVEVKKAELELVKEEAKESRDEKKINQAKAKVENKK
                     AEATRLKNIKTDREKAEEAKRRADAKLQEANVATSEQDKSKRRAKREVLGELATPDKK
                     ENDAKSSDSSVGEETLTSPSLKPEKKVAEAEKKVEEAKKKAEDQKEEDRRNYPTNTYK
                     TLELEIAESDVEVKKAELELVKEEAKESRNEEKIKQVKAKVESKKAEATRLENIKTDR
                     KKAEEEEAKRRAAEEDKVKEKPAEQPQPAPAPQPEKPTEEPENPAPAPAPKPENPAEK
                     PKAEKPADQQAEEDYARRSEEEYNRLTQQQPPKAEKPAQPSTPKTGWKQENGMWYFYN
                     TDGSMATGWLQNNGSWYYLNSNGAMATGWLQNNGSWYYLNANGSMATGWLQNNGSWYY
                     LNANGSMATGWLQYNGSWYYLNANGDMATGWLQNNGSWYYLNANGDMATGWLQNNGSW
                     YYLNANGDMATGWLQYNGSWYYLNANGDMATGWLQYNGSWYYLNANGDM"
BASE COUNT         6849 a         3604 c         4927 g         6286 t
ORIGIN      
        1 cacacgtaag gaaattgtta attggcatat caaggcgagt caatactatt tggagcccct
       61 ttataacctc ttgcgagaga gactattgac gcagtcctta cttcatgcgg atgaaacttc
      121 ttatagggtg ctagagagtg atagtcagct gacttactat tggacttttt tgtctgggaa
      181 agctgagaaa caagggatta cgctttacca tcatgtccta atcgatttgt tcatatctta
      241 tttcaatcca ttataaatag tgagaaatat ctatcctatc ttctagaatg tcttccaaac
      301 gtggaaactc tcgtaaacaa agaggtttta gaggcctatt taccatggac taaagttgta
      361 caagaaaagt gcaaataaga aatctccaga ttaggaacta tccgtgagtt ctctagtctg
      421 gagatttttc aatatacttc gttattggat ggttacaatt cataaagtgc tgtagagaga
      481 taacgttcac cgttatctgg tgctagggca aggacttttt tacctgtacc taattttttg
      541 gcaacctcaa tggctccgta gatagctgca gctgaggaaa tccctacaag gaagccttct
      601 tttccaccaa tttcacgtcc gagtgcaaga gcgtcatctg atgttacacg aacgatacca
      661 tcataggctt tagtatcaag tgtatcagga ataaatccag ctgagatacc ttgaattttg
      721 tgaggaccag gtttttcacc agatagaata gcagattcat ctgcttctac tgcaaaaact
      781 tgaatgttag aattttctga tttgagtgca tgagaaacac cagaaatcgt tccaccggta
      841 cctactccag caacaaaggc atctaatcca tctttaccga aagcagctag tatctcagct
      901 cctgttgttc tttcgtgtac ttctggatta gctggattgt caaattgaag aggaaggaaa
      961 ccatcacgtt cagcagcgat ttcttgagcc ttagcaatag cacctttcat tccctcgcta
     1021 ccaggagtta ggacgagttc agcaccataa gcttggataa ttttacgtcg ttctacactc
     1081 atagtttcag gcataacgat gacgacttta taccctttag cagcacctac ccatgaaagt
     1141 ccaataccag tgtttccact tgttgcttca acaatagtag aaccaggttt cagaatacca
     1201 tcttgttcag ctttttcaat catgctaagg gcaatacggt cttttacaga tgaaccagga
     1261 ttaaatgctt caagctttat atagacgtct gcagcacctt ctggcacgat gttgttaagt
     1321 ttaacaattg gtgtttgacc gattaattca gtaatgttgt tataaataga catatgaata
     1381 cctctttgta taagatatct ttagtataac gctatctata ccatttgtaa aatatagaaa
     1441 tcctatcgaa gcgataggat ttctatatat catagatcaa agtcattaat tttcaagtga
     1501 ttgcgttcag ctaattctag taaataggtg tgaaggaaaa cgatatcagg tttcgtttga
     1561 attgcttcat tttctagtat attttggtac gcatcttttt attttgctcg ctaaagtagt
     1621 tgtgagaatg tcaacgaaac gttgtattat tcattgttta cactaagttt acaggaactt
     1681 caacctctcg taaaccttgg tcagttaaag tgacttttcc attaaaaaac tccacaagtg
     1741 cagctttaat agtttctttt tcttctttat caacataaat catcgtatcg acttgatctg
     1801 taaagtttgt atccagctcc atgagatcat gttctttaag gaagttactg tactcttggt
     1861 actgagcata agacatttga atagcaatgc cagcctgttc ttttatttca ataataccaa
     1921 tttctttgac agctaaggcg acactgccgg cgtaagcacg aattagtcct ccagcgccta
     1981 gtttaatacc accaaagtag cgtgtcacga ccacacagac attggtgaga ttgtgatttt
     2041 ctagtacccc aagcatggga acaccagcag taccactagg ctcaccatca tcacttgtac
     2101 gtttaatttc actacgttct ccaataataa aggcagagca gttatgtgtc gctttgtagt
     2161 gttctttttt gatggcagta atgaagtcac gagcctcttc ttcgctataa acacgcttgg
     2221 catggcagat aaagcgagat tttttgattt cttcttggac ttggccgtcc tctttaattg
     2281 tcctaaattc catgatttaa ttgtactaaa aaatcatcta aagtgctagt ttttacgaat
     2341 aaagaagtat gaaagtaaat ttagattatc tcggtcgttt atttactgag aatgaattaa
     2401 cagaagaaga acgtcagttg gcggagaaac ttccagcaat gagaaaggag aaggggaaac
     2461 ttttctgtca acgttgtaat agcactattc tagaagaatg gtatttgccc atcggtgctt
     2521 actattgtcg agagtgcttg ctgatgaagc gagtcagaag tgatcaaact ttatactatt
     2581 ttccgcagga ggattttccg aagcaagatg ttctcaaatg gcgcggccaa ttaactcctt
     2641 ttcaagagaa ggtgtcagag ggactgcttc aagcagtaga caagcaaaag ccaaccttag
     2701 ttcatgcggt aacaggagct ggaaagacag aaatgattta tcaagtagtg gctaaagtga
     2761 tcaatgcggg tggtgcagtg tgtttggcta gtcctcgcat agatgtttgt ttggagctgt
     2821 acaagcgcct gcaacaggat ttttcttgcg ggatagcttt gctacatgga gaatcggaac
     2881 cttattttcg aacaccacta gttgttgcaa caacccatca gttattgaag ttttatcaag
     2941 cttttgattt gctgatagtg gatgaagtag atgcttttcc ttatgttgat aatcccacgc
     3001 tttaccatgc tgtcaagaat agtgtaaagg agaatggatt gagaatcttt ttaacagcga
     3061 cttcgaccaa tgagttagat aaaaaggtcc gtttaggaga actaaaaaga ctgaatttac
     3121 cgagacggtt tcatggaaat ccgttgatta ttccaaaacc aatttggtta tcggatttta
     3181 atcgctactt agacaagaat cgtttgtcac caaagttaaa gtcctatatt gagaagcaga
     3241 gaaagacagc ttatccgtta ctcatttttg cttcagaaat taagaaaggg gagcagttag
     3301 aagaaatctt acaggagcaa tttccaaatg agaaaattgg ctttgtatct tctgtaacag
     3361 aggatcgatt agagcaagta caagcttttc gagatggaga actgacaata cttatcagta
     3421 cgacaatctt ggagcgtgga gttaccttcc cttgtgtgga tgttttcgta gtagaggcca
     3481 atcatcgttt gtttaccaag tctagtttga ttcagattgg tggacgagtt ggacgaagca
     3541 tggatagacc gacaggagat ttgcttttct tccatgatgg gttaaatgct tcaatcaaga
     3601 aggcgattaa ggaaattcag atgatgaata aggaggctgg tctatgaagt gcttgttatg
     3661 tgggcagact atgaagactg ttttaacttt tagtagtctc ttacttctga ggaatgatga
     3721 ctcttgtctt tgttcagact gtgattctac ttttgaaaga attggggaag agaactgtcc
     3781 aaattgtatg aaaacagagt tgtcaacaaa gtgtcaagat tgtcaacttt ggtgtaaaga
     3841 aggagttgga gtcagtcata gagcgatttt tacttacaat caagctatga aggatttttt
     3901 cagtcggtat aagtttgatg gagacttcct gttaagaaaa gttttcgctt catttttaag
     3961 tgaggagttg aaaaagtaca aagagtatca atttgttgta attcccctaa gtcctgatag
     4021 atatgctaat agaggattta atcaggttga gggcttggta gaggcagcag gctttgagta
     4081 tctggattta ttagagaaaa gagaagagag agccagttct tctaaaaatc gttcagagcg
     4141 cttggggaca gaacttcctt tctttattaa aagtggagtc actattccta aaaaaatcct
     4201 acttatagat gatatctata ctacaggagc aactataaat cgtgttaaga aactgttgga
     4261 agaagctggt gctaaggatg taaaaacatt ttcccttgta agatgaggaa aaaatttgca
     4321 aaaatagaat gaaagcgtta taataaaatc ataaaaacaa aaatgtttag aaagaaggta
     4381 ctcatatgat taaatatagt atccgtggtg aaaacctaga agtaacagaa gcaattcgtg
     4441 attatgtagt ttctaaactc gaaaagatcg aaaagtactt ccaaccagaa caagagttgg
     4501 atgcccgaat taacttaaaa gtttatcgtg aaaaaacggc taaagtggaa gtaacgattc
     4561 cgcttggatc tattactctc cgcgcagaag atgtatctca agatatgtat ggttcaattg
     4621 accttgtaac tgataaaatt gaacgtcaga ttcgtaaaaa taaaacaaaa atcgagcgta
     4681 aaaataaaaa taaggtagca actggtcaat tatttacaga tgctttggtg gaagattcaa
     4741 atgttgtcca gtctaaagtt gttcgttcaa aacaaattga tttaaaacca atggatttgg
     4801 aagaagcaat tctacaaatg gatttattgg ggcatgattt ctttatctat gtggatgttg
     4861 aagatcagac aaccaatgtg atttatcgtc gtgaggatgg cgaaattggt ttgttagagg
     4921 ttaaagaatc ttaatttcaa tatgtgtaaa ggtaggttta ctgaattgta aactaccttt
     4981 ttcttataat tgatagaatt actgattaca cttttaaaaa gtcgcttttt gaggggtatt
     5041 atggtataat gggtgccaag aggttttgaa tgaaaaaatt ttatgtaagt ccaatttttc
     5101 ctattctagt aggattgatt gcgtttggag tcttatccac tttcattatt tttgttaata
     5161 ataatctgtt gacggtttta attttgtttc tttttgtagg aggctatgtt tttttattta
     5221 agaaactgag agtgcattat acaaggagtg atgtagaaca gatacagtat gtaaaccacc
     5281 aagcggaaga aagtttgaca tctctattgg aacaaatgcc tgtaggtgtt atgaaattga
     5341 atttatcttc tggagaggtt gagtggttta atccctatgc tgaattgatt ttgaccaagg
     5401 aagatggtga ttttgattta gaagctgttc aaacgattat caaggcttca gtaggaaatc
     5461 cgtctactta tgccaagctt ggtgagaagc gttatgctgt tcatatggat gcttcttccg
     5521 gtgttttgta ttttgtagat gtatccaggg aacaagccat aacagatgaa ttggtaacaa
     5581 gtcgaccagt gattgggatt gtctctgtgg ataattatga tgatttggag gatgcaactt
     5641 ctgagtcaga tattagtcaa atcaatagtt ttgtagctaa ttttatatca gagttttcag
     5701 aaaaatacat gatgttttct cgtcgggtaa gtatggatcg attttatcta tttactgact
     5761 acacggtgct tgagggcttg atgaatgata aattttctgt tattgatgct ttcagagaag
     5821 agtcgaaaca gagacagttg cccttgacct taagtatggg attttcttat ggcgatggaa
     5881 atcatgatga gatagggaaa gttgctttgc tcaatttgaa cttggctgaa gtacgtggtg
     5941 gcgaccaggt ggttgttaag gaaaacgacg aaacgaaaaa tccagtttat tttggtggtg
     6001 ggtctgctgc ttcaatcaag cgtacacgga ctcgtacgcg cgctatgatg acagctattt
     6061 cagataagat tcggagtgta gatcatgttt ttgtagtcgg tcacaaaaat ttagacatgg
     6121 atgctttggg ctctgctgta ggtatgcagt tgttcgccag caatgtgatt gaaaatagct
     6181 atgctcttta tgatgaagaa caaatgtctc cagatattga acgagctgtt tcattcatag
     6241 aaaaagaagg agttacgaag ttgttgtctg ttaaggatgc aatggggatg gtgaccaatc
     6301 gttctttgtt gattcttgta gaccattcaa agacagcctt aacattatca aaagaatttt
     6361 atgatttatt tacccaaacc attgttattg accaccatag aagggatcag gattttccag
     6421 ataatgcggt cattacttat atcgaaagtg gtgcaagtag tgccagtgag ttggtaacgg
     6481 aattgattca gttccagaat tctaagaaaa atcgtttgag tcgtatgcaa gcaagtgttt
     6541 tgatggctgg tatgatgttg gatactaaaa atttcacctc gcgagtaact agtcggacat
     6601 ttgatgttgc tagctatctc agaacgcgcg gaagtgatag tattgctatc caggaaatcg
     6661 ctgcgacaga ttttgaagaa tatcgtgagg tcaatgaact tattttacag gggtgtaaat
     6721 taggttcaga tgtactaata gcagaggcta aggacacgaa atgctatgat acagttgtta
     6781 ttagtaaggc agcagatgcc atgttagcca tgtcaggtat tgaagcgagt tttgttcttg
     6841 cgaagaatac acaaggattt atctctatct cagctcgaag tcgtagtaaa ctgaatgtac
     6901 aacggattat ggaagagtta ggcggtggag gccactttaa tttggcagca gctcaaatta
     6961 aagatgtaac cttgtcagaa gcaggtgaaa aactgacaga aattgtatta aatgaaataa
     7021 aggaaaagga gaaagaagaa tgaaagtaat ctttttagca gatgttaaag gaaaaggtaa
     7081 aaaaggcgaa attaaggaag taccaacagg gtatgcgcaa aactttctta tcaaaaagaa
     7141 tctagccaaa gaagcgactg ctcaagctgt aggtgaactt cgtggtaaac aaaaatcgga
     7201 agaaaaagct cacgctgaga tgattgcaga aggaaaagca attaaagcac aacttgaagc
     7261 agaagaaact gttgtagaat ttgttgaaaa agttggtcca gatggtcgta cctttggttc
     7321 tattaccaat aagaagattg cagaagaatt gcaaaagcaa tttggaatta agattgataa
     7381 acgtcatatt caagtacaag ctccgattcg agcggttggt ttgattgatg tgccagtgaa
     7441 aatctatcaa gatatcacaa gtgtaatcaa tcttcgtgtg aaagaaggat aagtttacac
     7501 cttcttgaca agattgtaaa aggaagggaa gtctgatggc agaagtagaa gagttacgag
     7561 tacaacctca agatatctta gctgagcaat ccgttttagg ggctatcttt attgatgaga
     7621 gtaaacttgt ttttgtgcga gaatacattg agtctcggga cttttttaag tatgcccatc
     7681 gtttgatttt ccaagccatg gtcgatttat ccgatcgtgg tgatgccata gatgcaacaa
     7741 cggttcgtac tatccttgat aatcaaggtg atttgcagaa tattggtggc ttgtcttact
     7801 tggttgagat tgtcaattct gtgccaactt ctgctaatgc ggagtattat gctaagattg
     7861 ttgcagaaaa agcaatgcta cgtcgtttaa ttgccaagtt gacagagtct gtcaaccaag
     7921 cttacgaagc gtcacaacca gctgatgaaa ttattgctca ggcagaaaaa gggttgattg
     7981 atgtcagtga aaatgcaaat cgaagcgggt ttaagaacat tcgagatgtg ttgaatctca
     8041 actttggaaa tctggaagct cgctcgcaac aaacgaccga tattacaggt attgcgacag
     8101 gttatcgtga tttggatcat atgacaacag gacttcatga ggaggagttg attatcttag
     8161 cagctcgtcc agcagttggt aagacagcat ttgccttgaa tatcgctcag aacattggga
     8221 ctaagttgga taaaacggtt gctatttttt cactcgaaat gggtgcggaa agcttggtag
     8281 atcgtatgtt agctgcagaa ggcttagtgg agtcacattc tatccgtaca gggcaattga
     8341 cagatgagga gtggcaaaaa tatactattg ctcagggtaa tctagctaac gccagtatct
     8401 atatcgatga tacgccaggt attcggatta cagagattcg ttctcgttct cgtaaattgg
     8461 ctcaagaaac tggaaatctt ggtttgattt tgatagacta tttgcaactt atcacgggaa
     8521 ctggtcgaga aaatcgtcaa caagaagttt ctgaaatttc tcgtcagttg aaaatactag
     8581 ccaaggaatt gaaggttcca gtaatcgctc tgagtcagct ttctcgtggt gtagaacaac
     8641 gtcaggacaa gagaccggtc ttgtctgata ttcgtgaatc tgggtctatt gagcaggacg
     8701 ctgatatcgt agcttttctc tatcgcgatg actactatga acgtggtggt gaagaagagg
     8761 agggtatccc aaataataag gtggaagtta ttatcgagaa aaaccgtagt ggagctcgtg
     8821 gaacagtgga attgattttc caaaaagaat acaataaatt ttcaagtatc tcaaagaggg
     8881 aggcataaga tgtcagatgc atttacagat gtagccaaga tgaaaaaaat caaagaagaa
     8941 atcaaggcac atgagggaca agtcgtagaa atgactttgg agaatggtcg taagcgccaa
     9001 aaaaatagat tgggtaagct aattgaagtt tatccatctc tatttattgt ggagtttggg
     9061 gatgtggaag gagataaaca agttaatgtt tacgttgaat cctttactta ctcagatatt
     9121 cttacagaaa agaatttgat tcattatctt gactaaagtg agaaattttc tcactttttc
     9181 ttttttctcc gaataattta ggtgaaggca atcatcgctt tatattattt ttcaaggagg
     9241 aagaatgaaa attttaccgt ttatagcaag aggaacaagt tattacttga agatgtcagt
     9301 taaaaagctt gttccttttt tagtagtagg attgatgcta gcagctggtg atagtgtcta
     9361 tgcctattcc agaggaaatg gatcgattgc gcgtggggat gattatcctg cttattataa
     9421 aaatgggagc caggagattg atcagtggcg catgtattct cgtcagtgta cttcttttgt
     9481 agcctttcgt ttgagtaatg tcaatggttt tgaaattccg gcagcttatg gaaatgcgaa
     9541 tgaatgggga catcgtgctc gtcgggaagg ttatcgtgta gataatacac cgacgattgg
     9601 ttccattact tggtctactg caggaactta tggtcatgtt gcctgggtgt caaatgtaat
     9661 gggagatcag attgagattg aggaatataa ctatggttat acagaatcct ataataaacg
     9721 aattataaaa gcaaacacga tgacaggatt tattcatttt aaagatttgg atggtggcag
     9781 tgttgggaat agtcaatcct caacttcaac aggcggaact cattatttta agaccaagtc
     9841 tgctattaaa actgaacccc tagttagtgc aactgtgatt gattactatt atcctggaga
     9901 gaaggttcat tatgatcaaa ttctcgaaaa agacggctac aagtggttga gttatactgc
     9961 ctataatgga agctatcgtt atgttcaatt ggaggctgtg aataaaaatc ctctaggtaa
    10021 ttctgttctt tcttcaacag gtggaactca ttattttaag accaagtctg ctatcaaaac
    10081 tgaaccccta gttagtgcaa ctgtgattga ttactattat cctggggaga aggttcatta
    10141 tgatcagata cttgaaaaag acggctacaa gtggttgagt tatacggctt ataacggaag
    10201 tcgtcgctat atacagctag agggagtgac ttcttcacaa aattatcaga atcaatcagg
    10261 aaatatctct agctatggat ccaataatag ttcaactgtc ggttggaaga aaataaatgg
    10321 tagttggtat catttcaaat caaatggttc taaatcaaca ggatggctga aagatggttc
    10381 tagctggtat tatttgaaat tatctggtga aatgcagaca ggatggttaa aggagaatgg
    10441 ctcgtggtat tatctgggta gttcaggggc aatgaaaaca ggctggtacc aggtctctgg
    10501 taagtggtat tattcttact cttcaggcgc cttagctgtt aatacgacgg tggatggcta
    10561 cagagtaaac agtgatggag aacgagtata gaaaattgga gtaggagaaa tttcctgctc
    10621 ttttctgtaa gcagtttcct tgacattttt cttattttgc gctatcatat atacatataa
    10681 tatatgggag tctgtgtaca gtctgagagg aagtgttaaa cttcgaccgc acctgatctg
    10741 ggtaatgcca gcggagggaa cgatacttag tctaattttg taccttttcc atgtatggta
    10801 aaggtttttc ttttttttaa aaggaaaacg agaagaggag gttcttatga aagcaagcat
    10861 tgccttgcaa gttttacccc tagtacaggg gattgatcgg atagctgtta ttgatcaggt
    10921 cattgcttat ctgcaaactc aagaagtgcc gatggtagtg acaccatttg aaacggtctt
    10981 ggaaggggag tttgatgagc ttatgcgcat tctaaaagaa gcgctggaag tggcagggca
    11041 ggaggcagac aatgtctttg ccaatgtcaa aataaatgta ggagagattt taagtattga
    11101 tgagaaactt gagaagtata ctgagacgac acattagtct attgggcttt ctcggagtct
    11161 tgtcaatctg gcagttagca ggttttctta aactgctccc caagtttatc ctgccgacac
    11221 ctcttgaaat tctccagccc tttgttcgtg acagagaatt tctctggcac catagctggg
    11281 cgaccttgag agtggcttta ctggggctga ttttgggagt tttgattgcc tgtcttatgg
    11341 ctgtactcat ggatagtttg acttggctca atgacctgat ttaccctatg atggtggtca
    11401 ttcagaccat tccgaccatt gccatagctc ctatcctggt cttgtggcta ggttatggga
    11461 ttttgcccaa gattgtcttg attatcttaa cgacaacctt tcccatcatc gtcagcattt
    11521 tggacggttt taggcattgc gacaaggata tgctgacttt gtttagtctg atgcgggcca
    11581 agccttggca aatcctgtgg cattttaaaa ttccagtcag cctgccctac ttttatgctg
    11641 gtctgagggt cagtgtctcc tacgctttta tcacaacagt ggtatctgag tggttgggag
    11701 gctttgaggg gcttggtgtt tatatgattc agtccaagaa attgtttcag tatgatacca
    11761 tgttcgctat tattattctg gtatcgatta tcagcctttt gggtatgaag ttggtcgata
    11821 ttagtgaaaa atatgttatt aaatggaaac gttcgtagaa ttagaatgtt tctgaaaaag
    11881 aaaagaggaa atcaaaatga agaaaacatg gaaagtgttt ttaacgcttg taacagctct
    11941 tgtagctgtt gtgcttgtgg cctgtggtca aggaactgct tctaaagaca acaaagaggc
    12001 agaacttaag aaggttgact ttatcctaga ctggacacca aataccaacc acacagggct
    12061 ttatgttgcc aaggaaaaag gttatttcaa agaagctgga gtggatgttg atttgaaatt
    12121 gccaccagaa gaaagttctt ctgacttggt tatcaacgga aaggcaccat ttgcagtgta
    12181 tttccaagac tacatggcta agaaattgga aaaaggagca ggaatcactg ccgttgcagc
    12241 tattgttgaa cacaatacat caggaatcat ctctcgtaaa tctgataatg taagcagtcc
    12301 aaaagacttg gttggtaaga aatatgggac atggaatgac ccaactgaac ttgctatgtt
    12361 gaaaaccttg gtagaatctc aaggtggaga ctttgagaag gttgaaaaag taccaaataa
    12421 cgactcaaac tcaatcacac cgattgccaa tggcgtcttt gatactgctt ggatttacta
    12481 cggttgggat ggtatccttg ctaaatctca aggtgtagat gctaacttca tgtacttgaa
    12541 agactatgtc aaggagtttg actactattc accagttatc atcgcaaaca acgactatct
    12601 gaaagataac aaagaagaag ctcgcaaagt catccaagcc atcaaaaaag gctaccaata
    12661 tgccatggaa catccagaag aagctgcaga tattctcatc aagaatgcac ctgaactcaa
    12721 ggaaaaacgt gactttgtca tcgaatctca aaaatacttg tcaaaagaat acgcaagcga
    12781 caaggaaaaa tggggtcaat ttgacgcagc tcgctggaat gctttctata aatgggataa
    12841 agaaaatggt atccttaaag aagacttgac agacaaaggc ttcaccaacg aatttgtgaa
    12901 ataatgacag aaattagact agagcacgtc agttatgcct atggtcagga gaggatttta
    12961 gaggatatca acctacaggt gacttcaggc gaagtggttt ccatcctagg cccaagtggt
    13021 gttggaaaga ccaccctctt taatctaatc gctgggattt tagaagttca gtcagggaga
    13081 attgtccttg atggtgaaga aaatcccaag gggcgcgtga gttatatgtt gcaaaaggat
    13141 ctgctcttgg agcacaagac ggtgcttgga aatatcattc tgcccctctt gattcaaaag
    13201 gtggataagg cagaagctat ttcccgagcg gataaaattc ttgcgacctt ccagctgaca
    13261 gctgtaagag acaagtatcc tcatgaactt agcggtggga tgcgccagcg tgtagcctta
    13321 ctccggacct acctttttgg gcacaagctc tttctcttag atgaggcctt tagcgccttg
    13381 gatgagatga caaagatgga actccacgct tggtatcttg agattcacaa gcagttgcag
    13441 ctaacaaccc tgatcatcac gcatagtatt gaggaggccc tcaatctcag cgaccgcatc
    13501 tatatcttga aaaatcgccc tgggcagatt gtttcagaaa ttaaactaga ttggtctgaa
    13561 gatgaggaca aggaagtcca aaagattgcc tacaaacgtc aaatcttggc agaattaggc
    13621 ttagataagt agaaaaatag ggagttggtg aagattatcc tttaccagcg ccctttttct
    13681 tttaaaaatg agaaaatttc ggtataatag tcaaacaagg tcaaggttta aagagagagg
    13741 tgggtttgtt atgagattta aaaatacatc ggatcatatt gaggcctaca tcaaggcgat
    13801 tttagatcaa tctggtatcg tggagttgca acggagtcag ttggcagata cctttcaggt
    13861 tgttcctagt cagattaact acgtgatcaa gacacgcttt acggaaagta gaggctactt
    13921 ggttgaaagt aagcgtggtg gcggaggcta cattcgtata ggacggattg agttttctag
    13981 tcatcatgaa atgctccggg agctgcttta ctcgattggt gagcgagtca gtcaagaaat
    14041 ttatgaggat attctccagc ttttggttga gcaggaattg atgaccaagc aggagatgaa
    14101 tttgctagaa tcagtagctt tggatcgcgt tttaggagaa gaagctccag ttgttcgagc
    14161 aaacatgcta cgtcagatca tacaagaggt agatagaaaa gggaagtaag atgaactatt
    14221 caaaagcatt gaatgaatgt atcgaaagtg cctacatggt tgctggacat tttggagctc
    14281 gttatctaga gtcttggcac ttgttgattg ccatgtctaa tcacagttat agtgtagcag
    14341 gggcaacttt aaatgattat ccgtatgaga tggaccgttt agaagaggtg gctttggaac
    14401 tgactgaaac ggactatagc caggatgaaa cctttacgga attgccgttc tcccgtcgtt
    14461 tgcaggttct ttttgacgaa gcagagtatg tagcgtcagt ggtccatgct aaggtgctag
    14521 ggacagagca cgtcttctat gcgattttgc atgatggcaa tgccttggca actcgtatct
    14581 tggagagggc tggtttttct tatgaagaca agaaagatca ggtcaagatt gctgctcttc
    14641 gtcgaaattt agaagaacgg gcaggctgga ctcgtgaaga tctcaaggct ttacgccaac
    14701 gccatcgtac agtagctgac aagcaaaatt ctatggccaa tatgatgggc atgccgcaga
    14761 ctcctagtgg tggtctcgag gattatacgc atgatttgac agagcaagcg cgttctggca
    14821 agttagaacc agtcatcggt cgggacaagg aaatctcacg tatgattcaa atcttgagcc
    14881 ggaagactaa gaacaaccct gtcttggttg gggatgctgg tgtcgggaaa acagctctgg
    14941 cgcttggtct tgcccagcgt attgctagtg gtgacgtgcc tgcggaaatg gctaagatgc
    15001 gcgtgttaga acttgatttg atgaatgtcg ttgcagggac acgcttccgt ggtgactttg
    15061 aagaacgcat gaataatatc atcaaggata ttgaagaaga tggccaagtc atcctcttta
    15121 tcgatgaact ccacaccatc atgggttctg gtagcggaat tgattcgact ctggatgcgg
    15181 ccaatatctt gaaaccagcc ttggcgcgtg gaactttgag aacggttggt gccaccactc
    15241 aggaagaata tcaaaaacat atcgaaaaag atgcggctct ttctcgtcgt ttcgctaaag
    15301 tgacgattga agaaccaagt gtggcagata gtatgactat tttacaaggt ttgaaggcga
    15361 cttatgagaa acatcaccgt gtacaaatca cagatgaagc ggttgaaaca gcggttaaga
    15421 tggctcatcg ttatttaacc agtcgtcact tgccagactc tgctatcgac ctcttggacg
    15481 aagcagcagc aacagtgcaa aataaggcaa agcatgtaaa agcagacgat tcagatttga
    15541 gtccagctga caaggccctg atggatggca agtggaaaca ggcagcccag ctaatcgcaa
    15601 aagaagagga agtacctgtc tacaaagact tggtgacaga gtctgatatt ttgaccacct
    15661 tgagtcgctt gtcaggaatc ccagttcaaa aactgactca aacggatgct aagaagtatt
    15721 taaatcttga agcagaactc cataaacgtg tcatcggtca agatcaagct gtttcaagta
    15781 ttagtcgtgc cattcgccgt aatcagtcag gaattcgcag tcacaagcgt ccgatcggtt
    15841 cctttatgtt cctaggaccc acaggtgtcg gtaagaccga gttggccaag gctttggcag
    15901 aagttctctt tgatgacgaa tcagccctta tccgctttga tatgagtgag tatatggaga
    15961 aattcgcagc cagccgtcta aatggagctc ctccaggcta tgtgggttac gaagaaggtg
    16021 gggagctgac agagaaggtt cgcaataaac cctattccgt tctcctcttt gatgaggtag
    16081 agaaggccca cccagatatc tttaatgttc tcttgcaggt tctggatgac ggtgtcttga
    16141 cagatagcaa gggacgcaag gtcgattttt caaataccat tatcattatg acatcgaatc
    16201 taggtgcgac tgcccttcgt gatgataaga ctgttggttt tggggctaag gatattcgtt
    16261 ttgaccagga aaatatggaa aaacgcatgt ttgaagaact gaaaaaagct tatagaccgg
    16321 aattcatcaa ccgtattgat gagaaggtgg tcttccatag cctatctagt gaccatatgc
    16381 aggaagtggt gaagattatg gtcaagcctt tagtggcaag tttggctgaa aaaggcattg
    16441 acttgaaatt acaagcttca gctctgaaat tgttagcaaa tcaaggatat gacccagaga
    16501 tgggagctcg cccacttcgc agaaccctgc aaacagaagt ggaggacaag ttggcagaac
    16561 ttcttcttaa gggagattta gtggcaggca gcatacttaa gattggtgtc aaagcaggcc
    16621 agttaaaatt tgatattgca taaaagaata aaagtatcag catctgacca taagtcacag
    16681 tggagtgaaa ctcaatgaaa atcaaagagc aaactaggca gctagccgca ggttgctcaa
    16741 aacactgttt tgaggttgca gatagagctg acgtggtttg aagagatttt cgaagagtat
    16801 aagctgcaag atgaatgatt ttcttgtatt gacgttgttg ttgacaaaaa gtagcggata
    16861 aatgaaatcc attccattat catagatgat agactggtag gaaattttca aatagcatac
    16921 aggaaataga tgtatggagt tctggtagta gaaagggaga gagatgaaca ttttagttgc
    16981 agatgacgag gaaatgatta gagaaggaat tgcagcattt ctgacagaag agggttatca
    17041 tgtcattatg gctaaggatg gacaagaggt cttggaaaaa tttcaagatc tccctatcca
    17101 tctcatggta ctggatttaa tgatgcctag gaagagtggt tttgaagtgt taaaagaaat
    17161 caatcaaaag cacgatattc ctgtcatcgt cttgagtgct ctgggagatg aaactactca
    17221 gtcacaggta tttgatctct atgctgatga tcatgtgaca aaaccttttt ctttggtact
    17281 gcttgtcaag cgtattaagg cgcttatcag acgttactac gtcatagagg atatttggcg
    17341 atatcaggat gtaacagtgg attttacctc ttacaaagca cattataaaa atgaagaaat
    17401 tgatctcaaa ccaaaggaat tactggtact aaagtgtttg attcagcata aaaatcaagt
    17461 tttaagtaga gagcagatat tggaagaaat ttcaaaagat gtagctgatt taccttgtga
    17521 tagggtcgtt gatgtctata ttcgtactct tcgcaaaaaa ttagctttag attgtatcgt
    17581 gactgtgaaa aatgttgggt ataagattag tttatgataa aaaatcctaa attattaacc
    17641 aagtcctttt taagaagttt tgcaattcta ggtggtgttg gtctagtcat tcatatagct
    17701 atttatttga cctttccttt ttattatatt caactggagg gggaaaagtt taatgagagc
    17761 gcaagagtgt ttacggagta tttaaagact aagacatctg atgaaattcc aagcttactc
    17821 cagtcttatt caaagtcctt gaccatatct gctcacctta aaagagatat tgtagataag
    17881 cgactccctc ttgtgcatga cttggatatt aaagatggaa agctatcaaa ttatatcgtg
    17941 atgttagata tgtctgttag tacagcagat ggtaaacagg taaccgtgca atttgttcac
    18001 ggggtggatg tctacaaaga agcaaagaat attttgcttt tgtatctccc atatacattt
    18061 ttggttacaa ttgctttttc ctttgttttt tcttattttt atactaaacg cttgctcaat
    18121 cctctttttt acatttcaga agtgactagt aaaatgcaag atttggatga caatattcgt
    18181 tttgatgaaa gtaggaaaga tgaagttggt gaagttggaa aacagattaa tggtatgtat
    18241 gagcacttgt tgaaggttat tcatgagttg gaaagtcgta atgagcaaat tgtaaaattg
    18301 caaaatcaaa aggtttcctt tgtccgtgga gcatcacatg agttgaaaac ccctttagcc
    18361 agtcttagaa ttatcctaga gaatatgcag cataatattg gagattacaa agatcatcca
    18421 aaatatattg caaagagtat aaataagatt gaccagatga gccacttatt ggaagaagta
    18481 ctggagtctt ctaaattcca agagtggaca gagtgtcgtg agaccttgac tgttaagcca
    18541 gttttagtag atattttatc acgttatcaa gaattagctc attcaatagg tgttacaatt
    18601 gaaaatcaat tgacagatgc taccagggtc gtcatgagtc ttagggcatt ggataaggtt
    18661 ttgacaaacc tgattagtaa tgcaattaaa tattcagata aaaatgggcg tgtaatcata
    18721 tctgagcaag atggctatct ctctatcaaa aatacatgtg cgcctctaag tgaccaagaa
    18781 ctagaacatt tatttgatat attctatcat tctcaaatcg tgacagataa ggatgaaagt
    18841 tccggtttgg gtctttacat tgtgagtaat attttagaaa gctatcaaat ggattatagt
    18901 tttctccctt atgaacacgg tatggaattt aagattagct tgtagacaga ttagtttttt
    18961 attaaagttc acatagggtt aacataagtg tattattctt tatatagata aaaatataga
    19021 taaaagaaag gatactaata tggtattagc gattatttta gtaacattcc ttattcgatt
    19081 gattttttta aagcgttcga tagagaatga gaaacgaatc cttagcaatg gcgggaaaga
    19141 atttggagtt gagaatacaa aacgattaac gttggctcat attgtttttt atctctcttg
    19201 cctcgttgaa gcaatggtgc ataagacaat gtttgatggc atgggcatgg ttggtttggt
    19261 cttgcttatt ttttctatgc tgatgttgat gttggtgatt cacttgttgg gagatatttg
    19321 gacagtgaag cttatgcttg tcaataatca caaatatgta gatcatatct tgtttaggac
    19381 agtaaaacac cctaattact ttttaaatat tttacctgag ttgattggct tgaccttgtt
    19441 gagtcatgcc tatatgactt ttgttttagt ttttccagtt tatgcagtta ttttgtatcg
    19501 acgaatagct gaagaggaaa agctattaca tgaagttata atcccaaatg gaagcataaa
    19561 gagataaata caaaattcga tttatataca gttcatattg aagtgatata gtaaggttaa
    19621 agaaaaaata tagaaggaaa taaacatgtt tgcatcaaaa aacgaaagaa aagtacatta
    19681 ttcaattcgt aaatttagta ttggagtagc tagtgtagct gttgccagtc tttttatggg
    19741 aagtgtggtt catgcgacag agaaggaggt aactacccaa gtagccactt cttctaataa
    19801 ggcaaataaa agtcagacag aacatatgaa agctgctaaa caagtcgatg aatatataaa
    19861 aaaaaagctc caattagata gaagaaaaca tacccaaaat gtcggcttac tcacaaagtt
    19921 gggcgtaatt aaaacggagt atttgcatgg attaagtgtt tcaaaaaaga agtcggaagc
    19981 tgagttgccg tcagaaataa aagcaaagtt agacgcagct tttgagcagt ttaaaaaaga
    20041 tacattacca acagaaccag gaaaaaaggt agcagaagct gagaagaagg ttgaagaagc
    20101 taagaaaaaa gccgaggatc aaaaagaaaa agatctccgt aactacccaa ccaatactta
    20161 caaaacgctt gaacttgaca ttgctgagtc cgatgtggaa gttaaaaaag cggagcttga
    20221 actagtaaaa gaggaagcta aggaatctcg agacgagaaa aaaattaatc aagcaaaagc
    20281 gaaagttgag aataaaaaag ctgaggctac aaggttaaaa aacatcaaga cagatcgtga
    20341 aaaagcagaa gaagctaaac gaagagcaga tgctaagttg caggaagcta atgtagcgac
    20401 ttcagagcaa gataaatcaa agaggcgggc aaaacgagaa gttcttggag agctagcaac
    20461 acctgataaa aaagaaaatg atgcgaagtc ttcagattct agcgtaggtg aagaaactct
    20521 tacaagccca tccctgaaac cagaaaaaaa ggtagcagaa gctgagaaga aggttgaaga
    20581 agctaagaaa aaagccgagg atcaaaaaga agaagatcgt cgtaactacc caaccaatac
    20641 ttacaaaacg cttgaacttg aaattgctga gtccgatgtg gaagttaaaa aagcggagct
    20701 tgaactagta aaagaggaag ctaaggaatc tcgaaacgag gaaaaaatta agcaagtaaa
    20761 agcgaaagtt gagagtaaaa aagctgaggc tacaaggcta gaaaacatca agacagatcg
    20821 taaaaaagca gaagaagaag aagctaaacg aagagcagca gaagaagata aagttaaaga
    20881 aaaaccagct gaacaaccac aaccagcgcc ggctcctcaa ccagaaaaac caactgaaga
    20941 gcctgagaat ccagctccag ctccagctcc aaaaccagag aatccagctg aaaaaccaaa
    21001 agcagaaaag ccagctgatc aacaagctga agaagactat gctcgtagat cagaagaaga
    21061 atataaccgc ttgactcaac agcaaccgcc aaaagcagaa aaaccagcac aaccatctac
    21121 tccaaaaaca ggctggaaac aagaaaatgg tatgtggtac ttctacaata ctgatggttc
    21181 aatggcgaca ggatggctcc aaaacaatgg ctcatggtac tacctcaaca gcaatggcgc
    21241 tatggcgaca ggatggctcc aaaacaatgg ttcatggtac tatctaaacg ctaatggttc
    21301 aatggcaaca ggatggctcc aaaacaatgg ttcatggtac tacctcaacg ctaatggttc
    21361 aatggcgaca ggatggctcc aatacaatgg ttcatggtac tacctcaacg ctaatggtga
    21421 tatggcgaca ggatggctcc aaaacaatgg ctcatggtac tacctaaacg ctaatggtga
    21481 tatggcgaca ggatggctcc aaaacaatgg ctcatggtac tacctaaacg ctaatggtga
    21541 tatggcgaca ggatggctcc aatacaatgg ctcatggtac tacctaaacg ctaatggtga
    21601 tatggcgaca ggatggctcc aatacaatgg ctcatggtac tacctaaacg ctaatggtga
    21661 tatgga
//
LOCUS       DAVHTH010000035        19999 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.035, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000035 DAVHTH010000000
VERSION     DAVHTH010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19999)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19999)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19999
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.035"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            complement(778..1647)
                     /locus_tag="VVR63_001376"
     CDS             complement(778..1647)
                     /locus_tag="VVR63_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEU6129389.1"
                     /translation="MDFTWALKYATEFLGTAILIILGNGAVANVELKGTKGHQSGWIV
                     IAVGYGMGVMIPALMFGNVSGNHINPAFTLGLAVSGLFPWAQVVPYIIAQVLGAIFGQ
                     ALVVATHRPFYLKTENSNNILGTFSTISSIDHGTKESRYAATVNGLINEFVGSFVLFF
                     AALGLTKNFFGAEVLQYMKQMATQAGQTVDFSDLAIKAQVAPHTASGLSVAHLALGFL
                     VMALVTSLGGPTGPALNPARDLGPRLLHAFLPKSVLGEHKGDSKWWYSWVPVVAPIAA
                     AIAAVAVFKFLYL"
     gene            complement(1871..2392)
                     /locus_tag="VVR63_001377"
     CDS             complement(1871..2392)
                     /locus_tag="VVR63_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEU6129390.1"
                     /translation="MVPKTATSTETKTITRIIHYVDKVTNQNVKEDVVQPVTLSRTKT
                     ENKVTGVVTYGEWTTGNWDEVVSGKIDKYKDPDIPTVESQEVTSDSSDKEITVRYDRL
                     STPDKPTPDPGTPKTETPVNPDPEVPTYETGKREELPNTGTEANATLASAGIMTLLAS
                     LGLGFFKKKEDEK"
     gene            complement(2350..3456)
                     /locus_tag="VVR63_001378"
     CDS             complement(2350..3456)
                     /locus_tag="VVR63_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HEU6129391.1"
                     /translation="MNIILIAKLLRENTNTKANALNNGWARSGSEEFKKFSHFVGVDK
                     GIVRTNVLTGKKLSDKIRKEVGSGDSKLGKGGYFSTGDVLLGKDVVSYTVQVFSENNE
                     RVGVNTQSHRVQYNLPILADFSVIQDTVEPSRTVVEKIIPKLNIPEEEKGKITEEIKK
                     KKKTSELAELISENVKVRYVDEQGRLLSLKNDTGIGEKESDGTYITNKKQLIGTSYNV
                     TDKKLSSMTTTDGKYYTFKEADTNSASLTGNIVSEGRTVTLVYRESEAPTTATVTANY
                     YKEGSQEKLAESVIKADLAIGSEYTTESKTIEGKTTTEDKEDRVITRKTTYTLVATPA
                     NAYQKTVQQLTITTVRMLRKQWFPKQQPLLRRRL"
     gene            complement(3567..3821)
                     /locus_tag="VVR63_001379"
     CDS             complement(3567..3821)
                     /locus_tag="VVR63_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6129392.1"
                     /translation="MLNVDQDFMSISKSNKSGSDWKKTFTVRTTNRLANDLNNVLKQA
                     DKDTPNTPTWLNSAASKAKDDDRAYKLLKTLIPGENYLSC"
     gene            complement(4161..4694)
                     /locus_tag="VVR63_001380"
     CDS             complement(4161..4694)
                     /locus_tag="VVR63_001380"
                     /inference="COORDINATES: protein motif:HMM:NF024751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HEU6129393.1"
                     /translation="MTSFKEQEPEKVAEFLDILDNLKDLPIVYIDETGIDRYLYRPYA
                     GAPRGEKVYEKISGRRFERTSIVAGQVDGEFIAPMIYKKSMTSDFFVEWFKTQLLPAL
                     KTPHVIVMGNASFHPKNILDELCIQDKHFFLPLPPYSPDLNPIEQAWAILKKKVTDLL
                     REVPTIFECLERFFKTR"
     gene            complement(4681..4896)
                     /locus_tag="VVR63_001381"
     CDS             complement(4681..4896)
                     /locus_tag="VVR63_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU6129394.1"
                     /translation="MGKERCEQGHIERKKRVVKNRKIPLEELKAFVEAHPDAFLREIA
                     AHFDCAVPSVWAALKQIKVTLKKDDEL"
     gene            complement(4863..5006)
                     /locus_tag="VVR63_001382"
     CDS             complement(4863..5006)
                     /locus_tag="VVR63_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tnpB"
                     /protein_id="HEU6129395.1"
                     /translation="MAYSTDFKQRALDYIKEGHSHVEAAKFFGVGVRTLFTWEKKDVN
                     KDT"
     gene            5240..6958
                     /locus_tag="VVR63_001383"
     CDS             5240..6958
                     /locus_tag="VVR63_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEU6129396.1"
                     /translation="MSYQENYQKWVDFVELPDYLRQDLENMDEKTKEDAFYTNLEFGT
                     AGMRGLVGAGTNRINIYVVRQATEGLARLIESKGGNEKERGVAIAYDSRHFSPEFAFE
                     SAAVLAKHGIKSYVFESLRPTPELSFAVRHLNCFAGIMVTASHNPAPFNGYKVYGEDG
                     GQMPPHDADALTTYIRAIENPFAVEVADVETEKASGLIEVIGEAVDVEYLKEVKDVNI
                     NPALIEEFGKDMKIVYTPLHGTGEMLARRALAQAGFDSVQVVEAQATADPDFSTVTSP
                     NPESQAAFALAEELGRQVGADVLVATDPDADRVGVEVLQKDGSYLNLSGNQIGAIMAK
                     YILEAHKNAGTLPENAALCKSIVSTDLVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMMGFEESFGYLIKPFVRDKDAIQAVLVVAELAAYYRSRGLTLADGIEEIYKE
                     YGYYAEKTISVTLSGVDGAEQIKAIMAKFRNNAPTEWNATAITVVEDFKAQTATVADG
                     TVTNLTTPPSDVLKYTLADGSWIAVRPSGTEPKIKFYIAVVGETNEESQAKITNIEAE
                     INAFVK"
     gene            7069..7416
                     /locus_tag="VVR63_001384"
     CDS             7069..7416
                     /locus_tag="VVR63_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEU6129397.1"
                     /translation="MEQFLDNIKDLEVTTVVRAQEALDKKETATFFIGRKTCPYCRKF
                     AGTLSGVVAETKAHIYFINSEEPSQLNDLQAFRSRYGIPTVPGFVHITDGQINVRCDS
                     SMSAQEIKDFAGL"
     gene            complement(7694..8530)
                     /locus_tag="VVR63_001385"
     CDS             complement(7694..8530)
                     /locus_tag="VVR63_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU6129398.1"
                     /translation="MKKWMLVLVSLMTALFLVACGKNSSETSGDNWSKYQSNKSITIG
                     FDSTFVPMGFAQKDGSYAGFDIDLATAVFEKYGITVNWQPIDWDLKEAELTKGTIDLI
                     WNGYSATDERREKVAFSNSYMKNEQVLVTKKSSGITTAKDMTGKTLGAQAGSSGYADF
                     EANPELLKNIVANKEANQYQTFNEALIDLKNDRIDGLLIDRVYANYYLEAEGVLNDYN
                     VFTVGLETEAFAVGARKEDTNLVKKINEAFSSLYKDGKFQEISQKWFGEDVATKEVKE
                     GQ"
     gene            complement(8543..9172)
                     /locus_tag="VVR63_001386"
     CDS             complement(8543..9172)
                     /locus_tag="VVR63_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU6129399.1"
                     /translation="MLELRNINKVFGDKQILSDFSLSIPEKQILAIVGPSGGGKTTLL
                     RMLAGLETIDSGQIFYNGQPLELDELQKRNLLGFVFQDFQLFPHLSVLENLTLSPVKT
                     MGMKQEEAEKKASGLLEQLGLGGHAEAYPFSLSGGQKQRVALARAMMIDPEIIGYDEP
                     TSALDPELRLEVEKLILQNRELGMTQIVVTHDLQFAENIADVLLKVEPK"
     gene            complement(9182..9823)
                     /locus_tag="VVR63_001387"
     CDS             complement(9182..9823)
                     /locus_tag="VVR63_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU6129400.1"
                     /translation="MSYLFEILPSLLNGASTTVQVFALVLLFSIPLGVLIAFALQVHW
                     KPLHYLINIYIWVMRGTPLLLQLIFIYYVLPSIGIRLDRLPAAIIAFVLNYAAYFAEI
                     FRGGIDTIPRGQYEAAKVLKFSPFDRVRYIILPQVTKIVLPSVFNEVMSLVKDTSLVY
                     ALGISDLILASRTAANRDASLVPMFLAGAIYLILIGIVTIISKKVEKKYSYYR"
     gene            complement(9969..11198)
                     /locus_tag="VVR63_001388"
     CDS             complement(9969..11198)
                     /locus_tag="VVR63_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HEU6129401.1"
                     /translation="MNNSQQMLQALEEQDLTKAEHYFAKALENDSSNLLYELATYLEG
                     IGFYPQAKEIYLKIVEDFPEVHLNLAAIASEDGQIEEAFTYLEEIQADSDWYVSSLVL
                     KADLYQLEGLTDVAREKLLEALTYSEDSLLILGLAELDSELENYQAAIQAYAQLDNRS
                     IYEQTGISTYQRIGFAYAQLGKFETATEFLEKALELEYDDLTAFELASLYFDQEEYQK
                     ATLYFKQLDTISPDFEGYEYGYSQALHKEHQVQEALRIAKQGLEKNPFETRLLLAASQ
                     FSYELHDASGAENYLLTAKEDAEDTEEILLRLATIYLEQERYEDILDLQSEEPENLLT
                     KWMIARSYQEMDDLDTAYEHYQELTGDLKDNPEFLEHYIYLLRELGHFEEAKVHAHTY
                     LKLVPDDVQMQELFERL"
     gene            complement(11188..12354)
                     /locus_tag="VVR63_001389"
     CDS             complement(11188..12354)
                     /locus_tag="VVR63_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEU6129402.1"
                     /translation="MEQKEKHFSLSWFFKWFLDNKAITVFLVTLLLGLNLFILSKISF
                     LFSPVLDFLAVVMLPVILSGLLYYLLNPIVDWMEKHKVNRVIAITIVFVIIALFIIWG
                     LAVAIPNLQRQVLTFARNVPVYLEDIDRIVNGLVAQHLPDDFRPQLEQVLTNFSSQAT
                     VLASKVSSQAVNWVSAFISGASQVIVALIIVPFMLFYLLRDGKGLRNYLTQFIPRKLK
                     EPVGQVLSDVNQQLSNYVRGQVTVAIIVAVMFIIFFKIIGLRYAVTLGVTAGILNLVP
                     YLGSFLAMLPALVLGLIAGPVMLLKVVIVFIVEQTIEGRFVSPLILGSQLNIHPINVL
                     FVLLTSGSMFGIWGVLLGIPVYASAKVVISAIFEWYKVVSGLYELEGEEVKSEQ"
     gene            12498..13511
                     /locus_tag="VVR63_001390"
     CDS             12498..13511
                     /locus_tag="VVR63_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HEU6129403.1"
                     /translation="MKETVYFGTYTRRTSQGIYKADFDTETGQLSNLELFAAEPSPTY
                     LAFDQHQHLYTVGSQDDKGGIAAYQTDGTVLNHVVEEGAPHCYVAVDEKRDLVYAANY
                     HKGQVLVYKRQEDGSLLLSDMDQHSGQGPHENQASPHVHYTDLTPDHYLVTCDLGTDQ
                     VITYDLDQEGKLSKLYTYHSKPGAGSRHIIFHNHYKIAYLICELNSTIEVLIYDGVGE
                     FERMQVISTLPEAYEGFNGTAAIHLSKDGKYLYASNRGHDSIAVYTILADGSLELLEI
                     VPTHGQTPRDFDLTPDQKFLIVVHQDSDNATVFKRNCDNGRLAELSNDFHVPEAVCIR
                     FAP"
     gene            complement(13556..13975)
                     /locus_tag="VVR63_001391"
     CDS             complement(13556..13975)
                     /locus_tag="VVR63_001391"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HEU6129404.1"
                     /translation="MAQLTVQIVTPDGLVYDHHASYVSVRTLDGEMGILPRHENMIAV
                     LAVDEVKVKRIDDKDHVNWIAVNGGVIEIANDMITIVADSAERARDIDISRAERAKLR
                     AERAIEEAQDKHLIDQERRAKIALQRAINRINVGNRL"
     gene            complement(13986..15392)
                     /gene="atpD"
                     /locus_tag="VVR63_001392"
     CDS             complement(13986..15392)
                     /gene="atpD"
                     /locus_tag="VVR63_001392"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HEU6129405.1"
                     /translation="MSSGKIAQVIGPVVDVLFAAGEKLPEINNALVVYKNDERKTKIV
                     LEVALELGDGMVRTIAMESTDGLTRGMEVLDTGRPISVPVGKETLGRVFNVLGDTIDL
                     EAPFTEDAERQPIHKKAPTFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFAGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLVQ
                     LGIYPAVDPLASSSRALAPEIVGEEHYAVAAEVKRVLQRYHELQDIIAILGMDELSDE
                     EKTLVARARRIQFFLSQNFNVAEQFTGQPGSYVPVAETVRGFKEILDGKYDHLPEDAF
                     RGVGSIEDVIAKAEKMGF"
     gene            complement(15478..16356)
                     /locus_tag="VVR63_001393"
     CDS             complement(15478..16356)
                     /locus_tag="VVR63_001393"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HEU6129406.1"
                     /translation="MAVSLNDIKTKIASTKNTSQITNAMQMVSAAKLGRSEEAARNFQ
                     VYAQKVRKLLTDILHGNGAGASTNPMLISRSVKKTGYIVITSDRGLVGGYNSSILKAV
                     MELKEEYHPDGKGFEMICIGGMGADFFKARGIQPLYELRGLADQPSFDQVRKIISKTV
                     EMYQNELFDELYVCYNHHVNTLTSQMRVEQMLPIVDLDPNEADEEYSLTFELETSREE
                     ILEQLLPQFAESMIYGAIIDAKTAENAAGMTAMQTATDNAKKVINDLTIQYNRARQAA
                     ITQEITEIVAGASALE"
     gene            complement(16372..17877)
                     /locus_tag="VVR63_001394"
     CDS             complement(16372..17877)
                     /locus_tag="VVR63_001394"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HEU6129407.1"
                     /translation="MAINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGL
                     ENVMSGELLNFENGSYGMAQNLESTDVGIIILGDFTDIREGDTIRRTGKIMEVPVGES
                     LIGRVVDPLGRPVDGLGEIHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGAL
                     DYTIVVTASASQPSPLLFLAPYTGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAFPGDVFYLHSRLLERSAKVSDELGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLGDGLFNAGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYREL
                     EAFTKFGSDLDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVTILYALTHGFLDTVPV
                     DDIVRFEEEFHAFFDAQHPEILETIRDTKDLPEEAVLDAAITEFLNQSSFQ"
     gene            complement(17892..18428)
                     /locus_tag="VVR63_001395"
     CDS             complement(17892..18428)
                     /locus_tag="VVR63_001395"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HEU6129408.1"
                     /translation="MDKKTVKVIEKYSMPFVQLVLEKGEEDRIFSDLTQIKQVVEKTG
                     LPSFLKQVAVDESDKEKTIAFFQDSVSPLLQNFIQVLAYNHRANLFYDVLVDCLNRLE
                     KETNRFEVTITSAHPLTDEQKTRLLPLIEKKMSLKVRSVKEQIDESLIGGFVIFANHK
                     TIDVSIKQQLKVVKENLK"
     gene            complement(18428..18922)
                     /gene="atpF"
                     /locus_tag="VVR63_001396"
     CDS             complement(18428..18922)
                     /gene="atpF"
                     /locus_tag="VVR63_001396"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HEU6129409.1"
                     /translation="MHVTVGELIGNFILITGSFILLLVLIKKFAWSNITGIFEERAEK
                     IASDIDRAEEARQKAEVLAQKREDELAGSRKEAKTIIENAKETAEQSKANILADAKLE
                     AGHLKEKANQEIAQNKVEALQSVKGEVADLTISLAGKIISQNLDSHAHKALIDQYIDQ
                     LGEA"
     gene            complement(18936..19652)
                     /gene="atpB"
                     /locus_tag="VVR63_001397"
     CDS             complement(18936..19652)
                     /gene="atpB"
                     /locus_tag="VVR63_001397"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HEU6129410.1"
                     /translation="MEESINPIISIGPVIFNLTMLAMTLLIVGVIFVFIYWASRNMTL
                     KPKGKQNVLEYVYDFVIGFTEPNIGSRYMKDYSLFFLCLFLFMVIANNLGLMTKLQTI
                     DGTNWWSSPTANLQYDLTLSFLVILLTHIESVRRRGFKKSIKSFMSPVFVIPMNILEE
                     FTNFLSLALRIFGNIFAGEVMTSLLLLLSHQAIYWYPVAFGANLAWTAFSVFISCIQA
                     YVFTLLTSVYLGNKINIEEE"
     gene            complement(19687..19887)
                     /locus_tag="VVR63_001398"
     CDS             complement(19687..19887)
                     /locus_tag="VVR63_001398"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HEU6129411.1"
                     /translation="MNLTFLGLCIACMGVSVGEGLLMNGLFKSVARQPDMLSEFRSLM
                     FLGVAFIEGTFFVTLVFSFIIK"
BASE COUNT         6006 a         4346 c         3607 g         6040 t
ORIGIN      
        1 taaaaattta actaattaat agaaagtact aaatagactt atccttcaag gagttttcag
       61 cattatccat ccactcactt gctgaaaatg taaacagtct ctggtttata tagtaaaatg
      121 aaacaagaat agagcaaatc gatcaggaca gtcaaatcga tttctaacaa tgttttagaa
      181 gtagatgtgt actattctag tttcaatcta ctatacaacc tcaaaactgt gttttgaaca
      241 acctgcggct agcttcttag tttgcccttt gattttcatt gagtataaaa ttgcagataa
      301 aacgataaca atcataggac tcagcagagt caatgtaggt cgaagaatag cccccctaat
      361 cgcttatttt atagcaaaat gaaatagaaa ctgaacattt tgttgaggaa ggtaaatcaa
      421 ttcctcacaa tgtttgagaa agaagggagg actattccaa cttcaaccca ctataaagca
      481 gacttacaag atagggaacc catctccgat aatatatagt agaatgaaaa ctgcacaatt
      541 tgattggaga attcaaacca atttctcaca atgttttaga aacaagggtc tattatttca
      601 actgcaacct actatagtcc attgaagctg gaatagccca ctgagacttc taaaccactg
      661 ctggagagga gtttgtttag actttctttc atttcctaga aaatcaaaaa gagagaacca
      721 atctgatcct ctcttactta tagatggtgc tcactcaaat gttaaaggag ctatttctta
      781 gagataaagg aatttgaata cagctactgc cgcaattgct gctgcaatcg gtgctactac
      841 tggtacccaa gaataccacc attttgaatc gcctttatgc tcaccaagaa ctgattttgg
      901 aaggaaagca tgaaggagac gtggtcccaa gtcacgggct gggttcaagg caggtcctgt
      961 aggtcctcca agtgatgtta ccaaagccat aacgaggaat ccaagtgcca agtgagccac
     1021 agaaagtcct gaagcagtgt gtggagccac ctgtgcttta atagccaagt cagaaaaatc
     1081 aactgtttgt cctgcttgtg ttgccatttg tttcatgtat tgaagcactt cagcaccaaa
     1141 gaagttttta gtcaaaccaa gagctgcaaa gaacaaaaca aatgaaccaa caaactcgtt
     1201 aatcaaacca ttgacagttg ctgcatagcg actttctttt gtaccatggt caatacttga
     1261 aatagttgag aaagttccca agatgttatt tgagttttca gttttcaagt agaatggacg
     1321 gtgtgttgcc acaactaagg cttgaccaaa gatagccccc aagacttgtg cgataatgta
     1381 aggtaccact tgtgcccaag ggaaaagacc gctaactgca agtcctagag tgaaagcagg
     1441 gttgatgtgg ttcccagata cgttaccaaa catcaaggct gggatcataa ctcccatacc
     1501 ataaccaaca gcgatgacga tccagccact ttggtgacct ttcgtacctt taagttcaac
     1561 gttggcaact gcaccattcc caagaatgat caaaatggca gttcccaaaa attcagtggc
     1621 atactttagt gcccatgtga aatccatttg ctagattctc cttaaaattt tttagatatt
     1681 ccttatttta tcaattttta ccctatttag caactagttt ctggaaagat tttttaaaaa
     1741 ataggattca tagtttccca gttcaacgga cttgtaagcg tttttattct tcacgaaaga
     1801 cctcgttctc aaaaccagga aaaaagccca catctgtgag cttttcctgg ttcctagatt
     1861 ctaaaatcta ttatttttca tcttcttttt tcttgaagaa tcctaatcct agactagcta
     1921 acaaggtcat gataccagca ctagccaagg tagcattagc ttctgtacct gtgtttggca
     1981 attcctctct cttacctgtc tcataagtcg gaacttctgg gtctggattc actggagttt
     2041 cagtttttgg agtacctggg tctggagttg gtttatctgg tgttgataaa cggtcatacc
     2101 ttaccgttat ttctttatca ctagagtctg acgtaacttc ttgtgattca actgttggaa
     2161 tatctggatc tttgtacttg tcaatcttac cagatacaac ctcgtcccag tttcctgttg
     2221 tccattcacc gtaggttaca actcccgtga ccttgttctc agtttttgta cggcttaagg
     2281 ttacaggttg aacaacatct tcttttacat tttggttcgt aactttatca acgtaatgaa
     2341 tgatacgcgt tatagtcttc gtctcagtag aggttgctgt tttgggaacc actgtttcct
     2401 caacattctc acggtagtaa tagtcaactg ttgcaccgtc ttctggtacg catttgcagg
     2461 agttgctacc aaggtgtatg ttgttttcct tgtgataact cggtcttctt tgtcctcagt
     2521 tgttgttttc ccttcaatag tttttgattc tgtggtatac tcagaaccta tcgctaaatc
     2581 agcttttata acagactctg ccaacttctc ttggctacct tctttatagt aattggctgt
     2641 tactgtagca gtggttggcg cttcgctttc tctataaact aaggtcactg ttctaccttc
     2701 gcttacaata ttcccagtta aacttgcaga atttgtatct gcttctttaa aagtataata
     2761 ttttccgtca gtagtagtca tgctactgag ttttttatct gtgacattgt agctggtacc
     2821 aatcagttgt tttttattgg taatgtaggt tccgtcactt tctttttctc caattccagt
     2881 atcatttttc aatgatagca aacgcccttg ttcatcaaca tagcgaactt tcacattttc
     2941 tgagattagt tctgccaatt ctgaggtttt tttctttttc ttgatttctt cggttatttt
     3001 ccctttctct tcttcgggaa tatttagttt tggaatgatt ttttcaacaa cggttcgtga
     3061 tggttccaca gtatcttgga tgactgaaaa gtcagctaga attgggagat tatactgaac
     3121 acggtgactt tgagtgttta ctcctactct ttcattattc tctgaaaata cttgtacggt
     3181 ataagaaaca acatcttttc ctaatagaac atccccagta gagaaatagc cgccttttcc
     3241 tagtttgcta tctccagagc ccacttcttt cctaatctta tcagatagtt ttttaccagt
     3301 cagtacattc gttcgcacaa tccctttgtc tacccctaca aagtgggaga actttttgaa
     3361 ctcttcagaa ccagatctag cccaaccatt attaagggca tttgcttttg tatttgtatt
     3421 ctctctcaaa agtttggcga ttagaattat attcatcggc acttagagtt gctgctatat
     3481 ctgactcttg aataccaact tccttactac catttctagc ggcagtatat gtgtatttat
     3541 ttgtttctac ttctagctga ttatccttaa catgataggt aattttctcc tggtataaga
     3601 gtcttcagta gtttatatgc tctgtcatca tctttagctt tagaagcagc tgagtttagc
     3661 caagttgggg tattaggagt atctttatca gcctgtttca agacattatt caagtcattt
     3721 gctagcctat tggttgtcct cactgtgaaa gttttcttcc agtctgaacc acttttatta
     3781 gacttagata tgctcatgaa atcctggtca acattcaaca caatatcgcc ttgtttttta
     3841 gcatcttccg ttgcttctgc ttcaaattga tcatggagtt tttgttgctc tggtgtatag
     3901 tttttttatt tacacgattt aatgtactat tttttatttt agtattaaga actccattaa
     3961 tacgattttt aaactctgct tcaaaaaatc ccttaatttg ttggtgcgca agttcaacat
     4021 tcaaaccttt cttatacaag tcttcattct gaacgatttc ggctacacgg tgaatggttt
     4081 gatcgtatac cgtcttctct taaccagcag tatccttagt tttaatgact actcgataag
     4141 ttcctttaga accgttatag tcatctagtt ttaaaaaagc gttccaaaca ttcaaaaata
     4201 gttggaactt cccttaataa atccgtcact ttctttttca agatagccca agcttgctca
     4261 ataggattca aatccggtga ataaggtggt agaggtaaga aaaagtgttt atcttggatg
     4321 cagagttcat ccaaaatgtt cttgggatga aaactagcat tgcccatgac aataacatga
     4381 ggtgtcttca aagcaggtag gagttgcgtt ttgaaccact ccacaaagaa atcgcttgtc
     4441 atgcttttct tgtaaatcat gggagctata aactctccgt ctacttgtcc tgcaacaatt
     4501 gaagttcgct caaaacgacg tccgctaatc ttttcataga ctttctcccc tctaggagcc
     4561 cctgcataag gacgatagag gtagcggtcg attcctgttt cgtcaatata tacgattggt
     4621 aaatctttta ggttatccaa aatatcaaga aactcagcga ctttctctgg ctcttgttcc
     4681 ttaaagctcg tcatcttttt ttaaagtgac cttaatctgc tttaaagctg cccatactga
     4741 aggaacagca caatcaaaat gtgccgcaat ttcccgtaaa aaagcatctg gatgagcctc
     4801 tacaaaggct ttcaattcct ctaaaggaat ctttcggttt ttgacgactc gctttttcct
     4861 ctctatgtgt ccttgttcac atctttcttt tcccacgtga agagagttct gacgccaaca
     4921 ccaaaaaact tggctgcctc gacatggctg tgcccctctt tgatgtaatc taatgctcgc
     4981 tgtttaaaat cagtactata tgccatagct ttattataat atgcttgttt aaaactaagc
     5041 aactatatca atgttttgtt attagaagac ttactttttt tactgaaatc gaatttttcc
     5101 taacctcaac atcatataac cccaaaattc aatctgacct ggtttgaaga gatgttcgaa
     5161 gcagataagg ttttactaaa actaaaaaaa atgatataat caaactgatt aaatgtttta
     5221 aaaataaagg agaatttgaa tgtcttacca agaaaattac cagaaatggg ttgattttgt
     5281 ggagcttcct gactaccttc gtcaagattt ggaaaatatg gacgaaaaaa ctaaggaaga
     5341 tgccttctat acaaatcttg aatttggtac tgcaggtatg cgtggcttgg ttggtgctgg
     5401 tacaaaccgt atcaacatct acgttgttcg ccaagctact gaaggattgg ctcgtttgat
     5461 tgagtcaaaa ggtggaaacg agaaagaacg cggtgtagca attgcctacg atagccgtca
     5521 cttctcacct gagtttgcct ttgaatctgc ggcagttctt gctaaacacg gcatcaaatc
     5581 ttacgtattt gaaagccttc gtccgactcc agaactatca tttgcagttc gtcatctcaa
     5641 ctgtttcgca ggtatcatgg tcacagccag ccacaaccct gctccattta acggttacaa
     5701 ggtttacggt gaagacggtg gacaaatgcc tccacacgat gcggacgctt tgactactta
     5761 tatccgtgca atcgaaaacc catttgcagt tgaagttgct gatgtggaaa ctgaaaaagc
     5821 ttctggcttg attgaagtta tcggcgaagc tgttgacgta gaatacctta aagaggttaa
     5881 ggacgtaaac atcaacccag ccttgattga agaatttggt aaagacatga agattgtcta
     5941 cacaccactt catggtactg gtgaaatgtt ggctcgtcgt gctcttgccc aagcaggatt
     6001 tgactctgtt caagttgttg aagcgcaagc aactgctgac ccagacttct caactgtaac
     6061 atctccaaac ccagaaagcc aagcagcctt tgcccttgct gaagaacttg gtcgtcaagt
     6121 tggtgcagat gttcttgtcg caactgaccc agacgctgac cgtgttggtg ttgaagttct
     6181 tcaaaaagat ggtagctacc tcaacctttc aggtaaccaa atcggtgcta tcatggctaa
     6241 atacatcttg gaagctcaca aaaacgctgg aactcttcct gaaaatgccg ctctctgcaa
     6301 atctatcgtt tcaactgact tggtaacgaa gattgctgaa agctacggcg caactatgtt
     6361 caacgtcttg acaggtttca aatttatcgc tgaaaaaatc caagaattcg aagaaaaaca
     6421 caaccacact tacatgatgg gatttgaaga aagcttcggt tacttgatta aaccatttgt
     6481 acgtgataaa gatgccatcc aagccgttct tgtcgttgct gaacttgctg cctactaccg
     6541 ttctcgtggt ttgacacttg ctgacggtat cgaagaaatc tataaagaat atggctacta
     6601 cgcagaaaaa acaatctctg ttactctttc aggtgtcgat ggtgctgaac aaatcaaagc
     6661 gattatggct aaattccgca acaatgctcc aacagaatgg aacgcaacag ctatcactgt
     6721 cgtagaagac ttcaaggcac aaactgctac tgttgctgac ggtactgtta caaacttgac
     6781 aactcctcca agtgatgtgt tgaaatacac acttgctgac ggttcatgga ttgccgttcg
     6841 cccttcaggt acagaaccaa aaatcaagtt ctacattgca gttgtagggg aaaccaacga
     6901 agaatcacaa gctaagatta ctaacatcga agcagaaatc aatgcatttg taaaataaag
     6961 acctataaaa gatgagacca accaacctca tcttttttcg tatcaaatct aagcaatttt
     7021 agaaacttta tggcatacta gacttatcaa tgaaagcgag gtaatctcat ggaacaattt
     7081 ttagataaca tcaaagacct tgaagtcact acagttgtgc gtgcgcaaga agctcttgat
     7141 aaaaaagaaa ctgcaacctt ctttatcggt cgcaaaactt gcccttactg ccgtaaattt
     7201 gcaggtacat tgtcaggtgt cgtagctgaa accaaagctc acatttactt catcaatagt
     7261 gaagaaccaa gccaactcaa tgatttgcaa gcattccgct cacgctatgg aatcccaact
     7321 gtaccaggtt ttgttcatat tacagatgga caaatcaacg tccgttgcga ctcttcaatg
     7381 tcagcacaag aaatcaaaga tttcgcagga ttgtaaaaaa tcagctaaca agtcttaaaa
     7441 tcacaaaaac gcataatgta aggtgcaaaa accttgatat tatgcgtttt attgttccta
     7501 aaacagttac atcagcattt cattacagaa cattttaatt ttggaagtca aatcaatttt
     7561 taacaatgtt ttagaaatca cagtgggcta ttccatattc aattatccag attcaatcgc
     7621 tattatcgtt ttcctagatt acaaaaaaac tacgttttgc taatcaaaac gcagtttcag
     7681 ccactatttt atcttactgt ccttctttta cttctttggt tgctacatct tctccaaacc
     7741 atttttggct gatttcttgg aacttgccgt ccttgtaaag actagaaaaa gcttcattta
     7801 tcttcttaac caagtttgta tcttccttac gggctccaac cgcaaaagct tctgtttcta
     7861 gtccaactgt aaagacatta taatcgttta aaacaccttc tgcttctaaa taatagtttg
     7921 catagacacg gtcaatcaat agaccatcaa ttcgatcgtt tttcaaatca atcaaggctt
     7981 cattaaaggt ttggtattga ttcgcttcct tattagcgac aatattcttc aaaagttctg
     8041 gatttgcttc aaagtccgca taaccagatg aaccagcttg agctcctaat gtctttccag
     8101 tcatatcctt tgcagtcgtg ataccagatg atttcttcgt aaccaatacc tgctcattct
     8161 tcatatatga gttactgaaa gccacctttt cacggcgttc gtctgtagcg gaatagccat
     8221 tccaaatcag atcaatcgtt ccttttgtca attcagcttc tttcaaatcc caatcaatcg
     8281 gttgccaatt taccgtgatt ccgtattttt caaaaacagc tgtagctaaa tcaatatcaa
     8341 atcctgcata agaaccatct ttctgagcaa atcccattgg aacaaaagta ctatcaaatc
     8401 caatagtaat agacttgtta gactggtact ttgaccaatt atctccacta gtttcgctag
     8461 aatttttccc acaagctact aagaacaaag cagtcatcag actgactaat acaagcatcc
     8521 attttttcat ccatttttcc tcctatttag gttctacttt caataataca tctgcgatat
     8581 tttcagcaaa ctgcaaatca tgggtaacca caatctgggt catcccaagt tccctatttt
     8641 gcaagattag cttctccact tccaaacgta attctggatc cagggcagaa gttggttcat
     8701 cgtagccaat gatttctggg tcaatcatca tagcacgcgc caaagccacc cgctgctttt
     8761 gcccaccaga tagtgagaaa ggataggcct ctgcgtgtcc tcctagtcct aactgttcca
     8821 agagtccact cgccttcttc tcagcctctt cctgcttcat tcccatggtc ttcacaggcg
     8881 ataaggtcaa attttccaga actgatagat gaggaaatag ttgaaaatct tggaagacaa
     8941 atcccagtag gttgcgcttc tgcaattcat ctagctctaa aggttgtcca ttataaaaga
     9001 tttgccctga atcaatggtt tcaagacctg caagcatacg taaaagagtt gtcttacctc
     9061 caccagaagg tccaacgata gccaggattt gcttttcagg aatacttaga ctgaaatcag
     9121 acaggatttg tttgtctcca aagactttat tgatatttcg taattctaac atagctgccc
     9181 cctatctata ataactgtac tttttctcaa cttttttgga aataattgtc acaatcccaa
     9241 ttaaaatcaa gtaaatggct cctgccaaga acataggaac cagactagca tcgcggttag
     9301 cagctgttcg actagccaag ataaggtctg aaattccgag agcatagacc aaagaagtat
     9361 ccttgaccaa actcataact tcattaaaga cactaggaag aacgatcttg gtcacttggg
     9421 gcaagataat atagcgcact ctgtcaaaag ggctaaactt caagaccttg gcagcctcat
     9481 actgtcctct tggaatagtg tcaattcccc cacggaaaat ttctgcaaag taagctgcat
     9541 agttgagaac aaaggcaata atagctgcag gaaggcggtc taaacgaatc ccaatacttg
     9601 ggagcacata atagataaaa atcagttgca agagtaaggg ggttcctcgc ataacccaga
     9661 tgtaaatgtt aatcagataa tggaggggct tccaatggac ttgcaaggca aaggcaatca
     9721 aaacgcccaa gggaatcgaa aatagcaaga ccagtgcaaa gacctgtaca gtcgtgctcg
     9781 caccattcag taaactcggt aatatctcaa ataaataaga catactgcac ctcctaaaag
     9841 taattgttcc tattatagca tgaataaaca agattaccaa gtatttttgt aaaaagattc
     9901 taccatatac aaataaaaac cgtagctatc aaaagagata aactacagtt ctatatgttt
     9961 aaacattctt acaatctctc aaacagttct tgcatttgca catcatctgg aaccagtttt
    10021 aagtaagtgt gagcatggac ttttgcttct tcaaaatgtc ccaattcacg caagagatag
    10081 atatagtgtt ccagaaattc tggattgtcc ttcaaatctc ctgtcaactc ttgataatgc
    10141 tcataagcag tatccaaatc gtccatttct tgataagaac gagcaatcat ccacttggtc
    10201 aaaagatttt ctggctcctc actctgcaag tctagaatat cctcataacg ctcctgctcc
    10261 agataaatag tggctaaacg aagcaagatt tcttctgtat cctcagcgtc ttcttttgca
    10321 gtaaggagat aattttctgc accactagca tcatgcaatt cataagaaaa ttgtgaagca
    10381 gctagcaaga ggcgagtttc aaagggattt ttctctaatc cttgcttagc gatacgcagg
    10441 gcttcttgaa cttgatgttc cttatgtaaa gcctgactgt acccatactc atagccttca
    10501 aagtcaggag aaatggtatc aagctgctta aagtagaggg tggctttttg atattcttct
    10561 tgatcaaaat aaagactggc caactcaaaa gctgttaagt catcgtattc taactccagg
    10621 gctttttcta aaaactcagt agccgtttca aatttcccta actgagcata ggcaaagcca
    10681 attcgttgat aggtggaaat gcccgtttgc tcataaatcg agcgattatc taactgggca
    10741 taggcttgaa tagccgcttg gtaattttcc aactcactat ccaactctgc caaacccaat
    10801 atcaagagag aatcctctga gtaggtcaag gcctccaata atttctcacg tgccacatct
    10861 gtcaaacctt ccagctggta aaggtctgcc ttcaaaacca aagacgagac ataccagtca
    10921 ctgtcagctt ggatttcctc aagataggta aaggcttctt ctatttgacc atcctcgcta
    10981 gcaattgcag ctagattaag atgaacctct ggaaaatcct ctacaatttt caggtaaatt
    11041 tccttggcct gaggatagaa accaatccct tcaagataag ttgccaactc atacagaaga
    11101 ttacttgaat cattttctaa agctttggcg aaataatgct cagccttagt taaatcttgc
    11161 tcctccaaag cctgtaacat ctgttgacta ttgttcactc ttgacttcct caccctctaa
    11221 ttcatataga ccactgacta ccttatacca ttcgaaaatg gctgaaatga caaccttagc
    11281 agaggcataa accggaatac caagtaaaac tccccagata ccaaacatag atcctgaagt
    11341 taacaaaaca aagagaacat taatagggtg gatgtttaat tgacttccca aaatcaatgg
    11401 agagacaaaa cggccttcaa tagtttgttc tacgataaag acaatcacta ctttcaaaag
    11461 catgactgga ccagcaatca aacccaatac tagagcagga agcatggcta gaaagctacc
    11521 aagataaggg accagattta aaataccagc agtaaccccc agcgtaaccg catagcgtag
    11581 accaataatc ttgaagaaga tgataaacat tactgctaca ataatagcca ctgtcacttg
    11641 ccctcgaaca tagttggaca actgttgatt cacatctgat agaacttgtc caacaggttc
    11701 cttcaatttt cttggaatga attgggtcaa atagttacgc aagcctttcc catcacgcaa
    11761 gagataaaag agcatgaaag gaacgataat caaggcaaca atcacttgag aagctccgct
    11821 aataaaggca ctcacccagt tgactgcctg agatgaaacc ttacttgcca aaactgtagc
    11881 ctggctagaa aaattggtca aaacttgctc taattgaggt ctgaaatcat ctggcaggtg
    11941 ctgggctacc aatccattaa caatcctatc tatatcttct aagtaaacag gaacgtttct
    12001 tgcaaaggtc aaaacctgac gttgcagatt tggaatggcg actgccaagc cccaaatgat
    12061 aaagagagcg atgataacaa agacaatagt gatagctata acacgattaa ccttatgctt
    12121 ctccatccaa tcaacaatag gattcaacaa ataatataac aaaccagaca aaatgactgg
    12181 caacatcaca actgctaaaa agtctaaaac aggtgaaaat agaaaactaa tcttacttaa
    12241 aataaaaaga ttcagtccca ataataaggt tactaaaaat accgtaattg ccttgttatc
    12301 taaaaaccac ttgaaaaacc aagataggct aaaatgtttc tctttttgct ccataaatac
    12361 ttcctttcta ttgttctctc attataccat ttttgaaaca aaataactct tttttaaagt
    12421 gcttacatct aattggatat ctttaattta cttgtttttg tgatataata gtcttatctt
    12481 tacacagagg tatagtaatg aaagaaactg tttattttgg aacttataca cgtcgtactt
    12541 ctcaagggat ttacaaggca gactttgata cagaaactgg tcagctttca aatctagaac
    12601 tttttgcagc tgagccaagt ccaacctacc ttgcctttga ccagcaccaa catttataca
    12661 ctgttggtag ccaagacgat aaggggggaa ttgcagccta tcaaactgac gggactgtgt
    12721 taaatcatgt tgttgaagaa ggagctcccc actgttatgt tgctgtcgat gaaaagcgtg
    12781 atttggttta cgcagccaac tatcacaagg gacaagtcct tgtttataaa cgccaggaag
    12841 atggtagtct tctacttagt gatatggatc aacacagtgg ccaaggtcca catgaaaatc
    12901 aagcttcccc ccatgttcac tatacagatt taacacctga ccactatcta gtgacctgcg
    12961 acttgggaac tgaccaagtc atcacctatg acctcgatca agaaggaaaa ttatctaagc
    13021 tctataccta tcacagcaag ccaggagcag gctcacgcca tatcattttc cataaccact
    13081 ataaaatcgc ttatctcatt tgtgaactca atagtactat cgaagtttta atctacgatg
    13141 gcgttggcga atttgaacgt atgcaggtca tttcaacttt accggaagct tacgaaggct
    13201 ttaatggaac cgctgctatt catctctcta aagacggtaa atacctctac gcttctaacc
    13261 gtggccatga ttctatcgca gtatatacca tccttgcgga cggtagctta gagttattag
    13321 aaatcgttcc aacgcatggt cagactccac gtgattttga tttgacaccc gaccaaaaat
    13381 ttctcattgt tgtccatcaa gactctgaca atgcaactgt ctttaaacgt aattgtgaca
    13441 atggtcgtct agcagaactc tccaacgact tccatgttcc cgaagcagtc tgcatccgtt
    13501 ttgctcctta aaacaccata aaaaatgaac ttggtatttt caagttcatt ttttcttata
    13561 gtctatttcc gacattaata cggttaatag cacgttgcaa agcaatctta gcacgacgtt
    13621 cttggtcaat caaatgtttg tcttgtgctt cttcaattgc acgttctgca cgaagtttgg
    13681 cacgttctgc acgactgata tcgatatcac gagcacgttc tgcagagtca gcgacgattg
    13741 tgatcatatc attggcaatt tcaataacac caccgtttac tgcaatccag ttcacgtgat
    13801 ctttatcatc gatacgtttt acctttactt catcaactgc taaaaccgca atcatatttt
    13861 catgtcgtgg caagatcccc atctcaccat ccagagttcg aaccgataca tagctggcat
    13921 ggtgatcata gacgagacca tctggtgtca cgatctggac agttaactga gccatagatc
    13981 acctcttaaa atcccatttt ttcagctttt gcaatcacat cttcgataga acctacacca
    14041 cggaaggcat cttctggcaa gtggtcgtat ttaccatcaa ggatttcctt aaagccacgt
    14101 acagtttcag caactggaac ataagaacct ggctgaccag taaattgttc cgcaacgttg
    14161 aagttttgtg acaagaagaa ctggatacga cgggcgcgag caaccaaggt cttttcttca
    14221 tcagaaagtt catccatacc aaggatagca atgatatctt gcaattcatg gtaacgttga
    14281 aggacacgtt ttacttcagc agcaactgca tagtgctctt ctccaacgat ttcaggtgcc
    14341 aaggcacgtg agcttgaagc aagtgggtca acggctgggt agatacccaa ttgtaccaac
    14401 ttacgttcca agtttgttgt tgaatccaag tgagcgaagg ctgttgctgg cgctgggtca
    14461 gtatagtcat ccgctggcac atagatagcc tggatagagg ttacagaacc cttcttggtt
    14521 gatgtgatac gttcttgcaa ttgacccatt tccgtagcaa gtgttggttg gtaaccaacg
    14581 gctgatggca tacgacccaa aagggcagat acttctgaac cagcctgagt gaaacggaag
    14641 atattatcga taaagagaag cacgtcttgg ccttccacat cacggaagta ttcagcgatt
    14701 gtcaaaccag taagggcaac acgcatacgt gctcctggtg gctcattcat ctgaccaaag
    14761 accatggctg ttttctcgat aacgcctgat tctttcattt cccagtaaag gtcattcccc
    14821 tcacgagtac gttccccaac accagcaaat actgaaatac caccgtgctc ttgggcaatg
    14881 ttgtgaatca attcttggat taagacagtt ttaccaactc cggcaccacc gaaaagtcca
    14941 actttaccac ctttaaggta aggggcaaga aggtcaataa ccttgatccc tgtttcaagg
    15001 atttcagaag aggtagacaa ctcatcaaaa gttggagctt ttttatgaat tggctgacgc
    15061 tctgcgtctt ctgtaaaagg agcttccaag tcaatggtat ctcccaaaac gttgaagaca
    15121 cgtcccaaag tttctttacc tactggtaca gagattggac gacctgtgtc caatacttcc
    15181 attccacgag tcaacccatc tgttgattcc atggcgatag tacgaaccat accatctcct
    15241 aactccaagg ctacttcaag gacgattttt gtttttcttt cgtcattttt gtagacgaca
    15301 agtgcattgt taatctcagg aagtttttcc cctgctgcaa acaaaacgtc tacaacggga
    15361 ccgataacct gagcaatttt acctgaactc atctccttct cctattctat ataagatact
    15421 gtcggttcct agctcaacta ggtcctaagt tcattttcat acgagctgga ctagagccta
    15481 ttctaaggca ctagcacctg ctacgatttc tgtaatttct tgtgtaatcg ccgcctgtct
    15541 ggcacggtta tactgaattg ttaaatcatt gatgactttc ttagcattat ctgtcgctgt
    15601 ttgcatggct gtcatacccg cagcattctc agctgtcttg gcatcgataa tggcaccgta
    15661 aatcatactt tctgcaaact gaggcaacaa ctgctccaga atttcttctc ggctggtttc
    15721 caattcaaaa gtcaagctgt actcttcatc cgcttcattt ggatccaagt caacaatcgg
    15781 aagcatttgt tccacacgca tttgactggt tagcgtattg acatggtggt tgtagcaaac
    15841 ataaagctca tcaaagagtt cattttggta catttcaaca gtttttgaaa taatcttacg
    15901 aacttgatca aagctaggtt ggtctgccaa gccacgtaat tcataaagtg gttgaatacc
    15961 gcgagcctta aagaaatcag ctcccatccc accgatacag atcatttcaa aacctttacc
    16021 gtctgggtgg tattcttctt tcaactccat aacagctttc aaaatagagg aattataacc
    16081 tccaaccaaa ccgcggtctg aagtgataac gatatagcct gtcttcttca cagaacggct
    16141 aatcaacatc ggattagttg aagcaccagc tccattacca tgaaggatat ctgtcaaaag
    16201 tttacgcact ttctgagcgt aaacttggaa gttgcgagca gcttcttcag agcgacctaa
    16261 cttagcagcc gataccattt gcatggcatt agtgatttga ctcgtatttt ttgttgaggc
    16321 gatttttgtt ttaatatcat ttagagacac tgccatctga cacctctatt cttattggaa
    16381 gctagattga ttgagaaact ctgtaatcgc agcatccaag actgcttctt ctggcaagtc
    16441 ttttgtatca cgaatggttt ccaaaatctc tggatgttga gcatcaaaga aggcatggaa
    16501 ctcttcctcg aaacgaacaa tatcatctac tggaacagta tccaagaaac catgtgtcaa
    16561 agcataaaga atggttactt gtttctcaac aggtaatggt ttgtgaacag gttgtttcaa
    16621 gacctcaacg gtacgacgtc cacggttcaa cttagcctgt gttgctgcgt ccaagtcaga
    16681 accaaactta gtaaaggctt ccaactcacg gtatgaagca aggtcgatac gaagtgtacc
    16741 agcaaccttc ttcatggctt tgatttgtgc agaaccacct acacgagata cagatgaacc
    16801 cgcatcgatg gctggacgaa tacctgcatt gaagaggcca tcgccaagga agatttgtcc
    16861 atcagtgata gaaatcacgt tggttgcgat ataggctgag atatctcctg cttgtgtctc
    16921 gataaatggt agggctgtaa ttgatccacc accaagttca tcagaaactt tagctgagcg
    16981 ctcaagcaaa cggctgtgga gatagaaaac atcccctggg aaggcttcac gacctggagg
    17041 acgacgaagc aagagcgaca gttcacgata agctaccgct tgttttgata gatcatcgta
    17101 tacaatcaaa acatgcttac cttgatacat aaattcttcc gccatagcga ccccagtata
    17161 aggagctagg aagagcaatg gagatggttg tgaagcagag gctgtcacaa cgattgtgta
    17221 gtccaaggca ccgtactgac gaagtgtttc tacttgcgta cgaactgttg attctttttg
    17281 tccaatcgcg acgtagatac agatcatatc ttgatctttt tggttcaaga ttgtatcaat
    17341 cgcaatggtt gttttccctg tctgacggtc accgataatc aactcacgtt gaccacgacc
    17401 aatcggtaca agggcgtcaa tagctttcaa accagtttgc aatggttctg aaacagactt
    17461 acgttgcata acaccaggag ctggtgcttc tactggacga gttttatcag tgtggatttc
    17521 tccaagaccg tcaactggac gaccaagcgg atccacaaca cgaccaatca gactttcacc
    17581 tacagggact tccatgattt tccctgtacg gcggattgta tcgccttcac ggatatctgt
    17641 aaagtcacct aggatgataa taccaacgtc tgttgactcc aagttttgag ccataccata
    17701 agagccgttt tcaaaattca acaactctcc actcatgaca ttttcaaggc cgtgagcacg
    17761 cgcgataccg tccccgatat aggttacaac acctgtttca gtcacatcaa aattgggttt
    17821 gaaattttca atttgttgct taattaaagc gctgatttct tgtgcgttaa ttgccaaaag
    17881 aacaccactt tctatttcaa attttcttta acaactttaa gttgttgttt aatactcaca
    17941 tcaattgtct tgtgattggc aaaaatgaca aaaccaccaa tgagactttc atcgatttgt
    18001 tcttttacac tccttacttt cagagacatt tttttctcaa tcaaagggag caaacgagtc
    18061 ttctgttcat cagttagagg atgagcagac gtaatcgtca cttcaaatcg atttgtttct
    18121 ttttcaagtc ggttcaagca atctacaagc acatcataaa aaagatttgc tctgtgattg
    18181 taggccagaa cctggataaa gttttgtaat aaaggcgaca cagaatcttg gaaaaaagca
    18241 attgtttttt ccttatccga ctcgtctact gccacttgtt ttaaaaaaga aggcagacct
    18301 gttttttcaa caacttgctt gatttgagtc aagtctgaaa agatacggtc ttcttctcct
    18361 ttttcaagta ccaattggac aaaaggcatg ctgtattttt caattacctt tactgttttc
    18421 ttgtccatta agcttctcct agctgatcga tatactgatc aatgagtgct ttatgggcat
    18481 gactgtcaag gttttgtgag atgattttac cagctaagct gatggtcaaa tctgcgacct
    18541 cacccttaac actctgtaaa gcttctactt tattttgagc aatttcttga ttggcttttt
    18601 cttttaagtg tcctgcttct agtttagcat ctgctaagat attagcctta ctttgctcag
    18661 ctgtttcctt tgcattttca atgattgtct tagcttcttt acggctacca gccaattcat
    18721 cttcgcgttt ttgagccaat acttctgctt tttgacgggc ttcttcagct ctgtcaatat
    18781 ctgaagcaat tttttcagct ctttcttcga aaatgcctgt aatattagac catgcaaatt
    18841 ttttaatcaa gactagcaaa agaataaaag agccagtgat taaaataaaa ttaccaatta
    18901 attcacctac tgttacgtgc atcagttact cctttctatt cctcttcaat attaatctta
    18961 ttccctaaat acacagatgt caaaagagta aaaacataag cttggatgca ggaaataaag
    19021 acagaaaatg cagtccaagc caaattagct ccaaaggcta ctggatacca ataaatagct
    19081 tggtgggaaa gaagaagtaa caaactcgtc atgacctctc ctgcaaagat attcccaaaa
    19141 atccgcaaag ccaaagataa gaagtttgta aattcttcca agatattcat cggtatgaca
    19201 aaaacaggac tcataaaaga ttttatactt tttttaaatc cacgacgacg aacgctttct
    19261 atatgtgtca acaaaatgac aagaaaagat aaggttaagt catactgtaa attagcggtt
    19321 ggcgaactcc accagttagt cccatcgatc gtttgaagct ttgtcattaa gccaaggtta
    19381 ttggcaatca ccatgaaaag gaataaacaa aggaaaaaga gtgagtaatc tttcatgtag
    19441 cgcgaaccaa tgttaggttc tgtaaatcca ataacaaagt catagacata ctcaagtaca
    19501 ttttgctttc ctttgggttt caaggtcata ttgcggcttg cccaataaat aaagacaaaa
    19561 ataactccca caatcaacaa agtcatggct aacatagtca gattgaagat aacaggacca
    19621 atagagatga ttggattaat actttcttcc atctaaaatc ctcccttttc ttctcgttcc
    19681 atgtatttat ttgataataa atgagaagac aagagttaca aagaaagttc cttcaataaa
    19741 ggcaacacct aaaaacatca aactacgaaa ctcagaaagc atatctggtt ggcgtgctac
    19801 tgatttaaac agtccattca tcaataaacc ttcaccgaca gatacgccca tacaggcaat
    19861 acataagcct aaaaatgtta aattcataac aaattctcct ttaaaataaa atttacttac
    19921 ttagtgtagt cctaaaattt aaatttgtca acttttaacc gctattggaa gcgtttaata
    19981 aaaattattt ccattttgc
//
LOCUS       DAVHTH010000036        18993 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.036, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000036 DAVHTH010000000
VERSION     DAVHTH010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18993)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18993)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18993
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.036"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            222..1667
                     /gene="cps4A"
                     /locus_tag="VVR63_001399"
     CDS             222..1667
                     /gene="cps4A"
                     /locus_tag="VVR63_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4A"
                     /protein_id="HEU6129412.1"
                     /translation="MSRRFKKSRSQKVKRSVNIVLLTIYLLLICFLLFLIFKYNILAF
                     RYLNLVVTALVLLVALVGLLLIIYKKAEKFTIFLLLFSILVSSVSLFAVQQFVGLTNR
                     LNATSNYSEYSISVAVLADSEIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNTDLT
                     VDQSSSYLAAYKSLIAGETKAIVLNSVFENIIESEYPDYASKIKKIYTKGFTKKVEAP
                     KTSKNQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVPIADG
                     GNNQKDKLTHAGIYGVDSSIHTLENLYGVDINYYVRLNFTSFLKMIDLLGGVDVHNDQ
                     EFSALHGKFHFPVGNVHLDSEQALGFVRERYSLADGDRDRGRNQQKVIVAILQKLTST
                     EALKNYSTIIDSLQDSIQTNMPLETMINLVNAQLESGGNYKVNSQDLKGTGRTDLPSY
                     AMPDSNLYVMEIDDSSLAVVKAAIQDVMEGR"
     gene            1669..2400
                     /gene="cps4B"
                     /locus_tag="VVR63_001400"
     CDS             1669..2400
                     /gene="cps4B"
                     /locus_tag="VVR63_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4B"
                     /protein_id="HEU6129413.1"
                     /translation="MIDIHSHIVFDVDDGPKSREESKALLTESYRQGVRTIVSTSHRR
                     KGMFETPEEKIAENFLQVREIAKEVADDLVIAYGAEIYYTLDALEKLEKKEIPTLNDS
                     RYALIEFSMNTPYRDIHSALSKILMLGITPVIAHIERYDALENNEKRVRELIDMGCYT
                     QVNSSHVLKPKLFGERYKFMKKRAQYFLEQDLVHVIASDMHNLDGRPPHMAEAYDLVT
                     QKYGEAKAQELFIDNPRKIVMDQLI"
     gene            2409..3101
                     /locus_tag="VVR63_001401"
     CDS             2409..3101
                     /locus_tag="VVR63_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000664160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular biosynthesis protein CpsC"
                     /protein_id="HEU6129414.1"
                     /translation="MKEQNTIEIDVFQLFKTLWKRKLMILIVALVTGTGAFAYSTFIV
                     KPEYTSTTRIYVVNRNQGDKPGLTNQDLQAGTYLVKDYREIILSQDALEKVATNLKLD
                     MPAKTLASKVQVAVPADTRIVSISVKDKQPEEASRIANSLREVAAEKIVAVTRVSDVT
                     TLEEARPATTPSSPNVRRNSLFGFLGGAVVTVIAVLLIELLDTRVKRPEDVEDVLKIP
                     LLGLVPDFDKIK"
     gene            3111..3800
                     /locus_tag="VVR63_001402"
     CDS             3111..3800
                     /locus_tag="VVR63_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein kinase"
                     /protein_id="HEU6129415.1"
                     /translation="MPTLEISQAKLDSVKKAEEYYNALCTNLQLSGDGLKVFSITSVK
                     IGEGKSTTSANIAWAFARAGYKTLLIDGDIRNSVMLGVFKARNKITGLTEFLSGTTDL
                     SQGLCDTNIENLFVIQAGSVSPNPTALLQSKNFTTMLETLRKYFDYIIVDTAPVGVVI
                     DAAIITRNCDASILVTEAGEINRRDIQKAKEQLEHTGKPFLGIVLNKFDTSVDKYGSY
                     GNYGNYGKNKK"
     gene            3815..5182
                     /locus_tag="VVR63_001403"
     CDS             3815..5182
                     /locus_tag="VVR63_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEU6129416.1"
                     /translation="MNEKILRSSLAIIQSFLVILLTYLLSAVRETEIVSTTAIALYIL
                     HYFVFYISDYGQDFFKRRYLIELVQTLKYILFFALAIGISNFFLEDRFSISRRGMIYF
                     LTLHALLVYVLNLFIKWYWKRAYPNFKGSKKILLLTATSRVEKVLDRLIESNEVVGKL
                     VAVSVLDKPDFQHDCLKVVAEGEIVNFATHEVVDEVFINLPGEKYNIGELVSQFETMG
                     IDVIVNLNAFDRSLARNKQIREMAGLNVVTFSTTFYKTSHVIAKRIIDIVGALVGLIL
                     CGLVSIVLVPLIRKDGGSAIFAQTRIGKNGRQFTFYKFRSMCVDAEAKKRELMEQNTM
                     QGGMFKVDDDPRITKIGCFIRKTSLDELPQFYNVLKGDMSLVGTRPPTVDEYEHYTPE
                     QKRRLSFKPGITGLWQVSGRSEIKNFDEVVKLDVAYIDGWTIWKDIEILLKTVKVVFM
                     RDGAK"
     gene            5213..6391
                     /locus_tag="VVR63_001404"
     CDS             5213..6391
                     /locus_tag="VVR63_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HEU6129417.1"
                     /translation="MKKSVYIIGSKGIPAKYGGFETFVEKLTAFQQDKAIQYYVACMR
                     ENSAKSGTTEDVFEHNGAICYNVDVPNIGPARAIAYDIAAINRAIEIAKENKDEDPIF
                     YILACRIGPFIHGIKKKIQEIGGTLLVNPDGHEWLRAKWSAPVRRYWKISEGLMVKHA
                     DLLVCDSKNIEKYIQEDYKQYQPKTTYIAYGTDTTRSVLKSSDEKVRSWFKEKNVSEN
                     EYYLVVGRFVPENNYESMIRGFLASNSKKDFVLITNVEQNKFYNQLLAKTGFDKDPRV
                     KFVGTVYEQELLKYIRENAFAYFHGHEVGGTNPSLLEALASTKLNLLLDVGFNREVAE
                     DGAIYWKKDNLHEIIETSEQKTQKEIDEKDILSIKQVTERFSWELIVNEYEKLFLCEK
                     "
     gene            6691..7884
                     /locus_tag="VVR63_001405"
     CDS             6691..7884
                     /locus_tag="VVR63_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polymerase"
                     /protein_id="HEU6129418.1"
                     /translation="MTIKINNLFFVCLSFFGIVLSSSQVIVNLGLSSIIQYISYFMLM
                     LCVFLTLIKNTLNVFANRIIYFLIISFLFIIGINLQNLPLSRKIYLSFSMLIISSLST
                     LPIKLINNLSDLRRISYYLLHSIFLSVFLGLVFKISLVTVAVEGIGFSYGFNGGLTHK
                     NFYAITILVSYILLYVSRKYDAKHQIDSFVLWLDLFLLLISNTRTVYIILVVFWIIIN
                     RNFINNIKKEHRLVVTATTIVISLLALTFFFKHIINNSESYSHRVLGVVNFFKYYESD
                     RFHLFFGDAELAFGNTTKGYGHNIRSVLGWDGTVEMPLLSVMIKNGYVGLVGYIIVLF
                     KFISSIISVKNSTKKNIGLSIFIPLLLSATVENYIVNISFVFMPVCFCILCSIKNIKL
                     VNNRK"
     gene            7888..8859
                     /locus_tag="VVR63_001406"
     CDS             7888..8859
                     /locus_tag="VVR63_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU6129419.1"
                     /translation="MEKLVSIILPVYNVEQYIKNCLESIQQQTYSNLEVIIVNDGSTD
                     KSVEYCEQICKIDSRFSITHKENGGLSDARNVGIDKSKGDYLIFVDSDDFVSQDMVSY
                     LVSCMENNEADIAICDPVHYYSDRQNNDLNIFSPASNVKVYETTEALCEMFYQKSFLV
                     SAWAKIFKRELFDDIRFPVGKLFEDSAIMYLLFEKCETIAYSDAELYAYVHRDNSITT
                     KKFSDRDLDILEITNTIINHYGDNLRVYTAAVSYKVSACFRILLNSPSGEKYKKVQKE
                     CLSYILQNWRNILFNNNVRLKNKLALISITIFNPFVKFIYSKVNRWE"
     gene            8866..10098
                     /locus_tag="VVR63_001407"
     CDS             8866..10098
                     /locus_tag="VVR63_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001045980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 61 protein"
                     /protein_id="HEU6129420.1"
                     /translation="MNKYEERYQENLSKNDFYKLINKSYLSDKELQVQQVKAGIVLPP
                     KAFETKLSNKLGLQKSLHGKGGVVDSNGNYIELSAQKAVGMRNRVYGPYKINYDNLPI
                     RNEKVIYLNYFIKQWGHFLLDVVGRLWYPLLQDNDTKLVYTCYAGTETKIEGNYLEFL
                     KLLGIDQSRLIMINCPTQFSEVIIPESSILPGGYYTKEYKQLFSSVVENIKLDKYDVN
                     AKMIYCSRSKLGIAKSKEFGEDGIEGIFKQNGYTSVYMETMSLEEQIKTLLSAKTIVL
                     TSGSLAHNLLFVNKDIDVFILNKTYRVNLHQFLINEISDATVRFVDIYRSPLPILYGY
                     GPFLMDLTKPLANFLDDNEFVYEKGTVLSKKDYFKYYLKWLWSYRFFLFRLNGIKEGN
                     SEFEKSFKIIRRYYKTGR"
     gene            10100..11485
                     /locus_tag="VVR63_001408"
     CDS             10100..11485
                     /locus_tag="VVR63_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000049683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HEU6129421.1"
                     /translation="MSKYKELAKNTGIFALANFSSKILIFLLVPIYTRVLTTTEYGFY
                     DLVYTTIQLFVPILTLNISEAVMRFLMKDGVSKKSVFSIAVLDIFIGSIAFALLLLVN
                     NLFSLSDLISQYSIYIFVIFVFYTLNNFLIQFSKGIDKIGVTAISGVISTAVMLAMNV
                     ILLVVFDWGLLGFFIANVCGYVIPCIYIVSRLRLWELFEIKIDKKLQWEMVYYALPLV
                     LNILSWWVNNTSDRYIVTAIVGIQASAIISVAYKIPQILSTISAIFIQSWQISAIKIQ
                     EDKSDTTFVSNMLLYYNALLLIIASGIILFVKPISNILFGISFYSAWELVPFLIISSL
                     FNAISGCIGAIMGAKMDTHNIAKSALVGMIANIILNIVLTFLMGPQGITISTLIASFL
                     IFYMRKDSVKEINSETYRAIYLSWILLVVEACLLIYMDFIIGALIAMVINLFLLKDVI
                     KPLYLKIFKRN"
     gene            11493..12641
                     /locus_tag="VVR63_001409"
     CDS             11493..12641
                     /locus_tag="VVR63_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000636508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-glycerol--glycerophosphate
                     glycerophosphotransferase"
                     /protein_id="HEU6129422.1"
                     /translation="MIVLQYFKILARFVFMFLISAVLLPFKIKPNKIVFINFNGKGYG
                     DNPKSICEYLRTTYPDLDLVWLARDNEGFPDGVRVVKYGTFQAFYEQASSKVWVYNVR
                     AFARILKKRGQIYIQTWHGASSFKLIEKQADLPINYVLEAKYDARVTDIMISDSRKQT
                     EEFQKYFWYSGEIFEVGMPRNDALFHYKEDYDKLNNIRKELSIHSDDYVILYAPTFRD
                     DGDASYLDINFERLLQCVEHGIKKKCKFLIRLHPNHSHLCNNISFNKNIINATFYSDM
                     QELTLLADVLVTDYSSSIFDFMLLNKPYVRYVNDLEKYAELRGVSDTYYELPDSIIKT
                     AEELYDLLPKKIENFDYDSIKKYRNEILCPIFNGTASENVGGRIIQEL"
     gene            12677..13705
                     /locus_tag="VVR63_001410"
     CDS             12677..13705
                     /locus_tag="VVR63_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000794266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HEU6129423.1"
                     /translation="MKNNDLKIGSGAIHQISATLSQNSISGKILYCADPVVDDLYGSI
                     VRSQIEEIGRVKEESCNYNTIAYAMNIAERAIATDIDCIVGMGGGRVLDVCKYASFIS
                     KRPYLSIPTTAANDGIASPVAVLKRQDDRPKSLGAAIPSMTLIDIDVIASGPIQNIKA
                     GIGDTISNYTALKDWELAVERGKDEMHGFAYLMSQNSLDALMKTKYNSITPDFIEVLV
                     NSLVLSGIAMDFAGSSRPVSGSEHLFSHALDYYGSTRNLHGIQVALGTVAVLKLIENS
                     VDTVVDYLQRFEVHINPKLLGIDEELFIYCMQHATKMRSNRYTYLHEVDLSTDRLKQI
                     YKELISEL"
     gene            13721..14425
                     /locus_tag="VVR63_001411"
     CDS             13721..14425
                     /locus_tag="VVR63_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocholine cytidylyltransferase family
                     protein"
                     /protein_id="HEU6129424.1"
                     /translation="MKALILAAGLGTRLAPITNEVPKSLVPVNGKPILMKQIENLYQN
                     NITDITIIAGYKSSVLTDAVTEKYPEINIIDNVDFKTTNNMYSAYLGKAAMGDSDFLM
                     MNADVFYDASVIKSLLLHKAPNAIVTDLGIYIEESMKVVEKNGRLVEISKQISPEETL
                     GASIDVYKFSYEAGARFFEKCKEFIEDKRELQMWSEVALNAILSEVEFVACPLEGRWL
                     EIDNHEDLVAAEKLFA"
     gene            14440..15273
                     /locus_tag="VVR63_001412"
     CDS             14440..15273
                     /locus_tag="VVR63_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000779205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IIA family hydrolase"
                     /protein_id="HEU6129425.1"
                     /translation="MKLTNRVDYFGADISELQNKKLFLFDMDGTIYEEDRLFEGTLEL
                     LDYIHNIGGEYIFITNNSSKSVVDYVEKVNRLGIKAERDNFFTSAQATIVYIKENYPK
                     SKVYCQGTKSLIKELSDAGIDVTEQVSADIDVVLVGFDTELTSDKIRNTCEILSTKDV
                     PFIATNPDIRCPVSFGFIPDCGSICDMISKSVDRKPVYIGKPEPTMVDIVRKKLNYSL
                     FETVVIGDRLYTDIMTGINAGVTSVCVLTGEATVNDIQQDSIKPTYTFKNVKEMWKGI
                     V"
     gene            15433..16302
                     /gene="rfbA"
                     /locus_tag="VVR63_001413"
     CDS             15433..16302
                     /gene="rfbA"
                     /locus_tag="VVR63_001413"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000676139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HEU6129426.1"
                     /translation="MKGIILAGGSGTRLYPLTRAASKQLMPVYDKPMIYYPLSTLMLA
                     GIRDILIISTPQDLPRFKELLQDGSEFGIKLSYAEQPSPDGLAQAFIIGEEFIGDDSV
                     ALILGDNIYHGPGLSTMLQKAAKKEKGATVFGYHVKDPERFGVVEFDENMNAISIEEK
                     PEYPRSNYAVTGLYFYDNDVVEIAKSIKPSPRGELEITDVNKAYLDRGDLSVELMGRG
                     FAWLDTGTHESLLEASQYIETVQRMQNVQVANLEEIAYRMGYISREDVLALAQSLKKN
                     EYGQYLLRLIGEA"
     gene            16303..16896
                     /locus_tag="VVR63_001414"
     CDS             16303..16896
                     /locus_tag="VVR63_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018029578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase family
                     protein"
                     /protein_id="HEU6129427.1"
                     /translation="MTDNFFGKTLAARKVEAIPCMLEFDIPVHGDNRGWFKENFQKEK
                     MLPLGFPESFFAEGKLQNNVSFSRKNVLRGLHAEPWDKYISVADGGKVLGSWVDLREG
                     ETFGNTYQTVIDASKGIFVPRGVANGFQVLSDTVSYSYLVNDYWALELKPKYAFVNYA
                     DPSLGIEWENIAEAEVSEADKNHPLLKDVKPLKKEDL"
     gene            16909..17958
                     /gene="rfbB"
                     /locus_tag="VVR63_001415"
     CDS             16909..17958
                     /gene="rfbB"
                     /locus_tag="VVR63_001415"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000141505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HEU6129428.1"
                     /translation="MTEYKNIIVTGGAGFIGSNFVHYVYENFPDVHVTVLDKLTYAGN
                     RANIEEILGNRVELVVGDIADAELVDKLAAQADAIVHYAAESHNDNSLNDPSPFIHTN
                     FIGTYTLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGHGEGPGEKFTAETKYNPSSP
                     YSSTKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILSGIKPKLY
                     GEGKNVRDWIHTNDHSSGVWTILTKGQIGETYLIGADGEKNNKEVLELILKEMGQAAD
                     AYDHVTDRAGHDLRYAIDASKLRDELGWKPEFTNFEAGLKATIKWYTDNQEWWKAEKE
                     AVEANYAKTQEIITV"
     gene            18024..18875
                     /gene="rfbD"
                     /locus_tag="VVR63_001416"
     CDS             18024..18875
                     /gene="rfbD"
                     /locus_tag="VVR63_001416"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HEU6129429.1"
                     /translation="MILITGANGQLGTELRYLLDERNEEYVAVDVAEMDITNEEMVEK
                     VFEEVKPTLVYHCAAYTAVDAAEDEGKELDFAINVTGTKNVARASEKHGATLVYISTD
                     YVFDGKKPVGQEWEVDDRPDPQTEYGRTKRMGEELVEKHVSNFYIIRTAWVFGNYGKN
                     FVFTMQNLAKTHKTLTVVNDQYGRPTWTRTLAEFMTYLAENRKEFGYYHLSNDATEDT
                     TWYDFAVEILKDTDVEVKPVDSSQFPAKAKRPLNSTMSLAKAKATGFVIPTWQDALQE
                     FYKQEVR"
BASE COUNT         6177 a         2814 c         3877 g         6125 t
ORIGIN      
        1 ttagattgaa actagagtag tacacctctg cttctaaaac attgttagaa atcgatttaa
       61 ctgtcctgat tgatttatcc tattcttgtt tcaatctact atatttttgt ttcgcgggaa
      121 gtctacttaa gatacttaaa gatgcagata gtaaaaaaga tgtagacatt accgtaaaaa
      181 agtgatataa tcgtatgatg ttcaaggtat aggtgttaat catgagtaga cgttttaaaa
      241 aatcacgttc acagaaagtg aagcgaagtg ttaatatcgt tttgctgact atttatttat
      301 tgttaatttg ttttttattg ttcttaatct ttaagtacaa tatccttgct tttagatatc
      361 ttaatctagt ggtaactgcg ttagtcctac tagttgcctt ggtagggcta ctcttgatta
      421 tctataaaaa agctgaaaag tttactattt ttctgttgct gttctctatc cttgtcagct
      481 ctgtgtcgct ctttgcagta cagcagtttg ttggactgac caatcgttta aatgcgactt
      541 ctaattactc agaatattca atcagtgtcg ctgttttagc agatagtgag atcgaaaatg
      601 ttacgcaact gacgagtgtg acagcaccga ctgggactga taatgaaaat attcaaaaac
      661 tactagctga tattaagtca agtcagaata ccgatttgac ggtcgaccag agttcgtctt
      721 acttggcagc ttacaagagt ttgattgcag gggagactaa ggccattgtc ttaaatagtg
      781 tctttgaaaa tatcatcgag tcagagtatc cagactacgc atcgaagata aaaaagattt
      841 ataccaaggg attcactaaa aaagtagaag ctcctaagac gtctaagaat cagtctttca
      901 atatctatgt tagtggaatt gacacctatg gtcctattag ttcggtgtcg cgatcagatg
      961 tcaatatcct gatgactgtc aatcgagata ccaagaaaat cctcttgacc acaacgccac
     1021 gtgatgccta tgtaccaata gcagatggtg gaaataatca aaaagataaa ttaacccatg
     1081 cgggcattta tggagttgat tcgtccattc acaccttaga aaatctctat ggagtggata
     1141 tcaattacta tgtgcgattg aacttcactt ctttcttgaa aatgattgac ttattgggag
     1201 gggtagatgt tcataatgat caagagtttt cagctctaca tgggaagttc catttcccag
     1261 tagggaatgt ccatctagac tctgagcagg ctctaggttt tgtacgtgaa cgctactcac
     1321 tagccgatgg agaccgtgac cgtggtcgca accaacaaaa ggttattgta gctatccttc
     1381 aaaaattaac gtcaaccgaa gcactgaaaa attatagtac gatcattgat agcttgcaag
     1441 attctatcca aacaaatatg ccacttgaga ctatgataaa tttggtcaat gctcagttag
     1501 aaagtggagg gaattataaa gtaaattctc aagatttaaa aggtacaggt cggacggatc
     1561 ttccttctta tgcaatgcca gacagtaacc tctatgtgat ggaaatagat gatagtagtt
     1621 tagctgtagt taaagcagct atacaggatg tgatggaggg tagatgaaat gatagacatc
     1681 cattcgcata tcgtttttga tgtagatgac ggtcccaagt caagagagga aagcaaggct
     1741 ctcttgacag aatcctacag gcagggggtg cgaaccattg tctctacctc tcaccgtcgc
     1801 aagggcatgt ttgaaactcc ggaagagaag atagcagaaa actttcttca ggttcgggaa
     1861 attgcaaaag aagtagcaga tgatttagtc attgcttatg gcgcagagat atactatact
     1921 ctggatgctc tagaaaagct agaaaaaaaa gaaattccta ccctcaatga tagtcgttat
     1981 gccttgatag agtttagtat gaacactcct tatcgcgata ttcatagcgc cttgagcaag
     2041 atcttgatgt tgggaattac tccagtcatt gcccacattg agcgctatga tgctcttgaa
     2101 aataacgaaa aacgtgttcg tgaactgatt gatatgggct gttacacgca agtaaatagt
     2161 tcacatgtcc tcaaacccaa actttttggc gaacgttata aattcatgaa aaaaagagct
     2221 cagtattttt tagagcagga tttggtccat gtcattgcaa gtgatatgca caatctagac
     2281 ggtagacctc ctcatatggc agaagcatat gaccttgtta cccaaaaata cggagaagcg
     2341 aaggctcagg aactttttat agacaatcct cgaaaaattg taatggatca actaatttag
     2401 gagaaatgat gaaagaacaa aacacgatag aaatcgatgt atttcaatta tttaaaacct
     2461 tgtggaaacg caagctaatg attttaatag tggcacttgt gacaggtacg ggggcttttg
     2521 catatagcac ttttattgtt aagccagaat atacgagtac cacgcgaatt tatgtagtga
     2581 atcgcaatca aggagacaag ccggggttga caaatcagga tttgcaggca ggaacttatc
     2641 tggtaaaaga ctaccgtgag attatccttt cgcaggatgc attggaaaaa gtagcgacaa
     2701 atttgaagtt ggatatgcca gcaaaaacgt tagccagcaa agttcaagtg gctgtgccag
     2761 ctgacactcg tatcgtctca atctctgtca aggataaaca gccagaggaa gccagtcgta
     2821 tcgctaattc tctacgagaa gttgctgcag aaaagatcgt cgctgtaacg cgagtatctg
     2881 atgtaacgac acttgaagaa gcgcgaccag ctacgactcc ctcttctcca aatgttcgac
     2941 gcaattcctt gtttggtttt cttggaggag cagtcgtaac agtaattgct gttcttttga
     3001 ttgagttgct cgacacccgt gtgaaacgtc ctgaagatgt tgaagatgta ctgaaaattc
     3061 cacttttagg gctcgttcca gattttgaca aaataaaata ggaggaagtt atgccaacat
     3121 tagaaatctc acaggcaaaa ttggattctg taaaaaaggc agaggaatat tataacgctt
     3181 tgtgcacgaa cctacagtta agtggagatg gtttgaaagt attttctatc acttctgtga
     3241 aaataggaga aggaaaatca acgacttccg ccaatatcgc ttgggctttt gcgcgtgcag
     3301 gttacaaaac gctgctgatt gatggagata ttcgcaattc tgttatgtta ggtgtcttta
     3361 aagcaaggaa taagattaca ggcctgacag aatttttatc aggaactaca gacctatcac
     3421 aagggctttg tgataccaat atcgaaaatc tctttgtaat tcaggctggc tctgtgtcac
     3481 cgaatccgac agctcttctt caaagtaaga atttcactac aatgcttgaa accttgcgta
     3541 aatattttga ctacatcatt gtagatactg ctcctgttgg tgtcgtgatt gatgcggcta
     3601 ttattacgcg aaactgcgat gcttctattt tagtgacgga ggcaggtgaa ataaatcgac
     3661 gggatattca aaaagcaaaa gaacagttgg aacacacagg aaagccgttt ttgggaattg
     3721 tgttgaataa attcgatact tcagtagaca aatacggttc ttatggaaat tatggaaatt
     3781 acgggaaaaa taaaaaatag gtcaggggat agagatgaat gaaaaaatat taagatcttc
     3841 attggccata attcagagtt ttcttgttat tttattgact tatctactta gtgctgtgag
     3901 agaaacggag attgtttcaa caacagctat tgcactttat atcctccatt attttgtctt
     3961 ttatatcagt gattatggac aggatttctt taaaaggaga tatttgattg aacttgtcca
     4021 gacattgaaa tatatcctat tctttgcact agcgattggt atttctaatt ttttcttaga
     4081 ggatcgattt agtatttcca gacgaggcat gatttacttc ctcacattac atgctctctt
     4141 agtctatgtg ctaaacctat ttatcaagtg gtattggaag cgggcttatc ccaactttaa
     4201 aggaagtaag aagattctct tacttacagc aacttctcgt gtcgaaaagg tactggatag
     4261 attaatagaa tcaaatgagg ttgttgggaa gttggtagcc gtcagtgtct tagataaacc
     4321 agattttcag catgattgtt taaaggtagt agcagagggg gagatagtaa actttgcgac
     4381 tcatgaggtg gtcgatgaag tctttatcaa tcttccaggt gaaaaataca atattggaga
     4441 gcttgtctct cagtttgaaa cgatgggaat tgatgtaata gtcaatctaa atgcttttga
     4501 tcgtagtttg gcacgtaaca agcaaattcg tgagatggca gggttaaacg ttgtgacttt
     4561 ttctacaaca ttttataaga ctagtcatgt aattgctaag cggattattg atatcgtggg
     4621 tgcattggta gggctgatac tatgtggttt agtcagtatt gtactggttc ctttgattcg
     4681 aaaggatggg ggatctgcta tttttgctca gacgcgtata ggaaaaaatg gtcgtcagtt
     4741 cactttttat aagtttcgct ctatgtgtgt agatgccgag gcgaaaaaaa gagaactcat
     4801 ggaacaaaat accatgcaag gtggaatgtt taaggtggac gatgatcctc gtatcacgaa
     4861 aattggttgt tttatacgga agactagctt ggacgagcta ccacagtttt ataatgttct
     4921 aaagggagat atgagtttgg ttggcacacg gccaccaaca gtggacgagt atgagcacta
     4981 taccccagaa caaaaacgcc gactaagttt taaacctggc ataacaggtt tatggcaggt
     5041 cagcggacga agtgagatca agaatttcga tgaagttgtc aaattagatg tggcctatat
     5101 tgatggttgg acaatctgga aagatattga aattttattg aagacagtta aagtagtatt
     5161 tatgagagat ggagcgaagt aatttctgta tatccatcat attaggagag aaatgaaaaa
     5221 gtcagtttat atcattggtt caaaaggaat tcctgctaag tatggaggat ttgaaacttt
     5281 tgttgagaaa ttaacagcct tccaacaaga taaggctatc caatattatg tggcttgtat
     5341 gcgtgaaaac tctgcaaaat cagggactac tgaggatgtt tttgaacata atggtgctat
     5401 ctgttataac gtcgatgttc ctaatattgg tccagcgcga gctatagcgt atgatatcgc
     5461 tgcaattaac agagctattg agattgccaa agaaaataag gatgaagatc caatcttcta
     5521 tattttagct tgtcgaattg gtccgttcat ccatggaatt aagaaaaaaa tccaggagat
     5581 aggtgggact cttctagtta atccagatgg ccacgagtgg ttgcgagcta agtggagtgc
     5641 tcctgttcgt cgctactgga aaatttctga aggtcttatg gtcaaacatg cagatctttt
     5701 agtgtgtgat agtaaaaata ttgaaaaata tatccaagaa gattataaac agtatcaacc
     5761 taagacaacc tatatcgctt atgggactga tacaacacgc tccgtattaa agagtagtga
     5821 tgaaaaagta cgttcttggt tcaaagagaa gaatgtttct gagaacgagt attatctagt
     5881 tgtaggacgt tttgtaccag aaaacaacta tgaatctatg attcgtggct ttttggcgtc
     5941 taactctaag aaggactttg tcttaatcac aaatgtagaa cagaataaat tttataatca
     6001 gttgttggca aaaactggtt ttgataagga cccacgagta aaatttgtag gtacagtcta
     6061 tgagcaagag cttcttaaat atattcgtga aaacgccttt gcttacttcc acgggcatga
     6121 agttggtgga accaatcctt cgcttttaga agctctggca tcaactaaac tgaatttatt
     6181 gctagatgtt ggctttaacc gagaagttgc tgaagatggt gccatttact ggaagaaaga
     6241 taatcttcat gagattattg aaacgagtga acaaaaaaca caaaaagaga ttgatgagaa
     6301 agatatactt tcaataaaac aagtgacgga gcggttctct tgggaattga tagttaatga
     6361 gtatgagaaa ctttttttat gtgagaaata atttacagtt tcatagaaat gttataaaaa
     6421 attaactctg aagaataatt acatattgga tttagaatgt tttttgctga ttcttgttgt
     6481 ttatggattt gaaaaaataa gagaagatgc ctcctttttg tcaggatatc tatgcaatgt
     6541 atacagaaat aatgactatt agctgattgt attattctcg aaattgtaat taaatataat
     6601 tgtattttgt ttttactata ttcgaaaata caagtgactt tatacaatca aatcaaaatc
     6661 tttcttgtta tttaataaaa ggaatcaagt gtgactataa aaattaataa tttgtttttt
     6721 gtttgtctat ccttttttgg gatagtttta agtagttcac aagtgatagt gaacttggga
     6781 ttgtctagta ttattcagta catttcttat tttatgttga tgttgtgtgt atttttaaca
     6841 ttaattaaga atactctcaa cgtgtttgca aatagaatca tatatttttt gattatttca
     6901 tttttgttta ttattgggat taatttacaa aatcttccat tatcaagaaa gatttattta
     6961 tcattctcta tgttaattat ttctagctta tccaccttac cgataaagct aataaataat
     7021 ctcagtgatt taagaaggat atcatattac ttattgcaca gcatattttt atctgtattt
     7081 ttaggtttgg tttttaaaat atctttagta acagttgctg tagagggaat tggcttttca
     7141 tatggtttta atggaggttt gactcataaa aatttttatg caattacaat tttagtttcc
     7201 tatattctac tatatgtcag cagaaaatat gacgctaaac atcagattga tagttttgta
     7261 ttatggttgg atcttttttt acttttaata tctaatacgc gaacagttta tataatacta
     7321 gttgtttttt ggattattat taatagaaat tttataaata atattaaaaa agagcataga
     7381 ctggtagtga cagcaacgac aatagtcatc tctttactgg cgttaacatt ttttttcaaa
     7441 catataatta ataatagtga atcatatagc catcgagtgt taggtgttgt gaattttttt
     7501 aaatattatg aatcagatag gtttcatttg ttttttgggg atgctgaatt agcctttgga
     7561 aatacgacga agggttatgg acacaatatt agaagtgtgt taggttggga tggaacggta
     7621 gagatgcctt tactcagtgt aatgattaaa aatggttatg ttgggttagt tggttacatt
     7681 atagtgctgt ttaagtttat atcttcaata atctcagtta aaaatagcac aaaaaaaaat
     7741 attggattat caatctttat tccgttactt ctatctgcaa cagttgaaaa ttatatcgtc
     7801 aacattagct ttgtattcat gcctgtctgc ttttgtattt tatgttcaat taaaaatata
     7861 aaattagtaa ataacagaaa gtaatatatg gaaaaattag ttagtattat tctgcccgtc
     7921 tacaatgtcg aacagtatat aaaaaattgt ttagaatcaa ttcaacaaca aacttattca
     7981 aatttggaag taatcattgt taatgacggt tcaaccgata aaagcgttga atattgtgag
     8041 caaatttgca agatagattc taggttttct atcactcaca aagaaaatgg tggactttcc
     8101 gatgcaagaa atgtcggtat agataaatcc aagggagatt acctcatttt tgttgacagt
     8161 gatgattttg tctctcaaga tatggtatct tatttagtat cttgtatgga gaacaatgag
     8221 gcagacattg ctatttgcga tcctgttcat tattacagtg atcgtcaaaa caatgatctt
     8281 aatatttttt ctccggcatc aaacgttaag gtttacgaaa caacggaggc tctatgtgag
     8341 atgttttatc aaaaatcttt tttggtgtct gcctgggcca agatatttaa aagagagttg
     8401 tttgatgata taagatttcc tgtaggtaag ctatttgaag atagtgcgat tatgtatttg
     8461 ctcttcgaaa aatgtgaaac aattgcatac tctgatgcgg aattatatgc ttatgtacac
     8521 agggataata gcatcacaac aaagaaattt tcggatagag acttagatat tttggagatt
     8581 acgaacacaa ttattaatca ctatggtgat aatttacgcg tgtatactgc agcggtgtct
     8641 tataaggtat ctgcatgttt cagaattcta ttaaactcac cttctggaga aaagtataaa
     8701 aaagtacaaa aagaatgtct gagttatatt ttacaaaatt ggagaaacat attatttaat
     8761 aataatgttc gattgaagaa caagcttgcc ttaatttcta taactatttt caatcctttt
     8821 gttaaattta tctatagtaa agtaaacaga tgggaatgat agcaaatgaa caaatatgaa
     8881 gaaagatatc aagaaaattt atctaagaat gatttttata aattaattaa taagagttac
     8941 ttatcagata aagaacttca agtacaacaa gtaaaagctg ggatagtctt accaccaaag
     9001 gcatttgaaa caaaattatc aaataaactt ggcctacaaa aatctttgca tggaaagggt
     9061 ggagttgtag actcaaatgg aaattacatt gaactatctg cacaaaaagc agtcgggatg
     9121 agaaatagag tctatggtcc gtataaaatt aattacgata atctgccaat tagaaatgaa
     9181 aaagtaatct atttgaacta tttcatcaaa caatggggac attttttact ggatgttgtt
     9241 ggaaggttat ggtatccatt gctgcaggat aatgatacta agttagtcta tacctgctat
     9301 gctggaacag aaacaaagat tgagggaaac tatttagagt ttttgaagct tctcggcata
     9361 gatcaatcac gtttaatcat gataaactgt cccactcagt tctcagaagt cattattcct
     9421 gaaagctcca ttttaccggg gggatattat acaaaagagt ataaacaact attcagttcg
     9481 gtagtagaaa atattaaatt ggacaagtat gatgtgaatg ctaaaatgat ttattgttcg
     9541 aggtctaaat tagggattgc taaaagtaaa gaatttggcg aagacggtat tgaggggatt
     9601 tttaaacaaa atggctacac atctgtttac atggaaacaa tgtctttgga agagcaaata
     9661 aaaaccttat tatcggctaa gacaatagta ttaacgagtg gttcgttagc acataatctt
     9721 ttatttgtaa ataaagatat tgatgttttt attttgaata aaacctatag agtaaatctc
     9781 catcaatttt taataaacga gatctcagat gctacagtaa gatttgtaga tatctatcga
     9841 tcacctttac cgattttata cggatatgga ccatttttaa tggatcttac aaaacctttg
     9901 gctaatttct tggacgataa tgaatttgta tatgaaaaag gtactgtttt aagtaaaaaa
     9961 gattatttta aatactattt gaaatggttg tggagttata gattcttttt atttaggtta
    10021 aatggtatta aagaaggaaa tagtgaattc gagaagagtt ttaagataat taggagatac
    10081 tataaaacag gacgatagaa tgagtaaata taaggaatta gcaaaaaata caggtatttt
    10141 tgctttggct aacttttcat caaagatttt aatttttttg ttagtaccta tatatacacg
    10201 ggtacttacc actacggaat atggttttta tgacttagtc tatacaacta ttcagctttt
    10261 tgtaccaatc ttgacattaa atatatctga agccgttatg aggttcctaa tgaaagatgg
    10321 tgtttctaaa aaatcagtct tttcaattgc tgttttagat atatttattg gatcaattgc
    10381 ttttgcttta ttgttgttag taaataacct gttttcttta tcagatttaa tttctcaata
    10441 cagtatttac atatttgtaa tctttgtttt ctatacccta aataattttt tgatacaatt
    10501 ttctaaggga attgataaaa ttggtgttac agctatctct ggggtcataa gtacagcagt
    10561 tatgcttgcc atgaatgtca ttcttctagt agtatttgat tggggattgt taggtttctt
    10621 tattgctaat gtttgtggat atgttatacc ttgtatttat atagtttcta gattaagatt
    10681 gtgggaatta tttgaaatta agattgataa aaaattacaa tgggaaatgg tttactatgc
    10741 tttgccatta gttttaaata tattaagctg gtgggtaaat aatacttcag atagatatat
    10801 tgtgactgca atagtaggta tacaagctag tgcaattatt tcagtcgctt ataaaattcc
    10861 acagattttg tctacgatta gtgcaatttt tattcaatca tggcaaatct ctgcaattaa
    10921 aatacaagaa gataagagcg atactacatt tgtatcaaac atgctcctat actataatgc
    10981 acttctattg attatagcga gtggtatcat attatttgtc aaacctattt ctaatatatt
    11041 gtttggtatt tccttctatt ctgcgtggga gctggtacca tttttaataa ttagcagtct
    11101 attcaatgca atttcaggtt gtataggagc aattatggga gctaaaatgg atactcataa
    11161 cattgcaaag tcggctttag ttgggatgat tgcaaatatt attttaaata tagtgttaac
    11221 attcttaatg ggtccacagg gaattacaat ttctaccctg atagctagtt ttcttatttt
    11281 ttatatgcga aaagatagtg taaaagaaat taattcagaa acatatagag caatttattt
    11341 atcgtggata ctattagttg tagaggcctg tctgctaatt tatatggatt ttattattgg
    11401 tgctttaata gcaatggtaa taaacttatt tttactaaaa gatgttatca aacctttata
    11461 tttaaaaatt ttcaaaagaa attaggtaca aaatgattgt tttacaatac tttaagattt
    11521 tagctagatt cgtttttatg tttttgataa gtgcggtgtt actgcctttc aaaataaaac
    11581 ctaataagat tgtttttatt aatttcaatg ggaaaggata tggtgataat ccgaaaagta
    11641 tttgtgagta tcttagaact acttacccag atttagattt ggtttggctt gcaagagata
    11701 acgaaggttt tccagatggg gttagggttg ttaaatatgg gactttccaa gctttttatg
    11761 agcaagcgag ttcgaaggtt tgggtatata atgtaagagc ttttgcaaga atactaaaaa
    11821 aacgaggaca gatttatatt caaacttggc atggtgcttc tagttttaag ttgatagaaa
    11881 aacaagctga tttaccaata aattatgttt tagaagctaa gtatgatgca agagtcacag
    11941 atataatgat ttcagatagc agaaaacaaa ctgaagaatt tcaaaagtat ttttggtatt
    12001 caggagaaat ttttgaggtg gggatgccga gaaatgatgc cttgtttcac tataaggaag
    12061 actacgacaa gttaaataat atcagaaaag aactaagcat tcattcagat gattatgtta
    12121 ttttatatgc ccctactttc agagatgatg gggatgcatc ttatttagat ataaattttg
    12181 aacggctttt gcaatgtgtt gaacacggaa ttaaaaagaa atgtaaattc ttaattaggt
    12241 tacaccctaa tcactcccat ttgtgtaata atatttcatt taataagaat ataatcaatg
    12301 ctacgtttta ttcagatatg caagagctta ctttgttggc agatgtttta gtcacagatt
    12361 attcttcctc gatatttgat tttatgcttt taaacaagcc ttatgtcaga tatgtgaatg
    12421 atttagaaaa atatgctgag cttagggggg tatcagatac atattacgaa ttgccggatt
    12481 cgattattaa aactgctgaa gaattgtatg acttactgcc taaaaaaata gaaaattttg
    12541 attatgattc tataaaaaaa tatagaaatg aaatactgtg tccaatcttt aatggaaccg
    12601 ctagtgaaaa tgtaggaggg agaataattc aagagttgtg aagtaaaaca ttgggttatt
    12661 tttaaggtaa cgagatttga aaaataatga tttaaagata ggaagtggag ctattcatca
    12721 aatttccgct acactttctc aaaatagtat ttcgggaaag attttatatt gtgctgatcc
    12781 agttgtcgat gacttgtacg gttcgatagt acgttcacaa atagaggaaa ttggtcgggt
    12841 aaaggaagaa agttgcaatt ataatactat tgcttatgcg atgaatatag cagaacgggc
    12901 tattgccaca gatattgact gtattgtggg aatgggagga ggtcgtgttt tagatgtctg
    12961 caagtatgca tcttttattt cgaaacgtcc ttacctatcg attccgacaa cagcagcaaa
    13021 tgatggcatt gcttccccag ttgctgtttt gaaaaggcag gatgatagac caaaaagctt
    13081 aggggcggct atcccctcaa tgacactaat tgatattgat gttattgcat caggacctat
    13141 acaaaatata aaagctggta tcggtgatac aatatccaat tacactgcat tgaaagattg
    13201 ggagttggca gttgagcgag ggaaagatga gatgcatggt tttgcatatc taatgtcgca
    13261 aaattcttta gatgctttaa tgaaaacgaa gtataattct attacccctg attttattga
    13321 agttttggta aactctttag ttttatcagg cattgcaatg gattttgcgg gaagtagtag
    13381 acctgtcagt gggtcagagc acttatttag tcatgcatta gattactatg gttctacaag
    13441 gaatcttcat ggaattcagg ttgcattagg tacagtcgca gttttgaaat taattgaaaa
    13501 ttctgttgat actgtagtgg attacttgca aagatttgag gttcatatta acccgaaact
    13561 tttggggata gatgaagagt tgtttattta ttgtatgcaa catgctacaa aaatgagaag
    13621 taatcgctat acctatctgc atgaagttga tcttagcaca gatagattga aacaaatata
    13681 taaggaactc ataagcgagt tgtagagaag agaggaaaaa atgaaagcac ttattttagc
    13741 agcagggtta ggaacacgtc tagctccaat taccaatgag gtaccaaaat ctttggtacc
    13801 agtcaatggt aagccaattt tgatgaaaca aattgaaaat ttatatcaaa ataatattac
    13861 agatattacg attattgctg gatataagtc atctgtatta acagatgcag ttactgaaaa
    13921 gtatccagaa attaatatta ttgataatgt tgattttaaa acgactaata atatgtattc
    13981 agcctatcta ggaaaagctg caatgggtga tagtgacttc ttaatgatga atgcagatgt
    14041 attttatgat gcttctgtta ttaaaagtct gttgcttcat aaagctccaa atgcaattgt
    14101 aactgattta ggtatttata ttgaagagtc tatgaaagtc gtagaaaaaa atggtcgttt
    14161 agtagaaatt tctaaacaga tttcacctga ggaaacttta ggagcttcta ttgatgttta
    14221 taaattctct tatgaagcag gtgctcgatt ctttgaaaag tgtaaggaat ttattgaaga
    14281 taaacgagaa cttcaaatgt ggagtgaggt tgctcttaat gcaattcttt ctgaagttga
    14341 atttgtagca tgtccattag agggtcgttg gttagaaatt gataatcatg aagacttagt
    14401 tgctgcagaa aaactatttg cttgaaccga atacggagaa tgaaattgac aaatagagtt
    14461 gattattttg gtgctgatat tagtgaactt cagaataaaa aattattctt atttgatatg
    14521 gatggtacca tttatgaaga agataggttg tttgagggta ctctcgaatt attagactat
    14581 attcataata ttggcggtga gtatattttt attacaaaca attcatctaa gtctgttgtt
    14641 gactatgttg aaaaagttaa cagattaggt attaaagctg aacgagataa tttttttacc
    14701 tctgctcaag ccacaattgt ttatattaaa gaaaattatc ctaaatctaa agtttattgc
    14761 caaggaacaa aatctttgat aaaagaacta tctgacgcag gaattgatgt aactgagcaa
    14821 gttagtgctg atatagatgt tgttcttgtt ggttttgata cagaattaac cagtgataaa
    14881 attcgcaata cctgcgagat tctatcaaca aaggacgtac ctttcatagc tactaaccct
    14941 gatattcgct gcccagtatc gtttggattc atcccggatt gtggttctat ttgtgatatg
    15001 attagtaaat cagtcgatag gaaacctgtt tacataggta aacctgaacc tacgatggtt
    15061 gatattgttc gaaaaaaatt aaattattct ctatttgaaa cagttgtgat tggagatcgc
    15121 ttgtatacgg atatcatgac tggtataaat gcaggagtaa cttcagtttg tgtgctgaca
    15181 ggagaagcaa cggtgaatga tattcaacaa gatagtataa aaccgactta tacatttaaa
    15241 aacgtgaaag aaatgtggaa aggaattgtc tgattttttc attctgaata gtgaattcat
    15301 gaatactgtc aaaatactcg tatgtattta aattgatttt attattttaa taatggacaa
    15361 attaaaatta tttttctccc caaatcgttc gtgaacgtaa agtactcatc aacaaagaaa
    15421 ggtacccctt ttatgaaagg tattattcta gcaggtggtt cgggaactcg cttgtatcct
    15481 ttgactcgcg ctgcatcaaa acaacttatg ccggtttatg ataaaccgat gatttactac
    15541 ccactttcaa cattaatgtt ggctgggatt agggatattt tgattatctc aactcctcaa
    15601 gatttgcctc gttttaaaga gcttcttcaa gatggttctg agtttggtat taaactttct
    15661 tatgctgagc aaccaagtcc agatggtttg gcacaagcct ttatcattgg ggaagagttt
    15721 atcggtgacg atagcgttgc cttgatttta ggtgacaata tctaccatgg tcctggtctg
    15781 agcacaatgc ttcaaaaagc agccaagaaa gagaaaggtg cgactgtttt tggctaccat
    15841 gtcaaggatc cagaacgctt tggtgttgta gaatttgatg aaaatatgaa tgctatctcc
    15901 atcgaagaaa agccagaata ccctcgttca aactatgcag tgacaggact ctatttctat
    15961 gataatgatg tagtagagat tgccaaaagt attaaaccaa gtcctcgtgg tgaattggaa
    16021 attacagatg tcaacaaggc ttacttggat cgtggtgatt tgtctgttga gctcatggga
    16081 cgtggttttg cttggttgga tactggcact catgaaagtt tactagaggc ttcgcagtac
    16141 atcgaaacag tccaacggat gcaaaatgtt caggtagcaa acttagaaga aattgcttac
    16201 cgtatgggct atatcagtcg agaagatgta ttggccttag cccaatcact taagaaaaat
    16261 gaatacggac agtatctgct ccgtttgatt ggagaagcat agatgacaga taattttttc
    16321 ggtaagacgc ttgcggcacg caaggttgaa gctattccat gcatgttgga gtttgatatc
    16381 cccgttcatg gagataatcg tggctggttt aaagaaaatt tccaaaagga aaaaatgctt
    16441 ccacttggat ttccagagtc tttctttgca gaaggaaaat tgcaaaacaa tgtatccttc
    16501 tcacgtaaaa atgtccttcg aggcctccac gcagagcctt gggataagta catctctgta
    16561 gcagatggag ggaaagttct gggttcttgg gttgatctac gcgagggtga aacctttggg
    16621 aatacctatc agacagtgat tgatgcgagt aagggaatct ttgttcctcg aggcgtagct
    16681 aatggcttcc aagttttatc agatacagtg tcatatagct atctggtcaa tgattactgg
    16741 gctcttgaac tcaaacccaa gtatgccttt gtgaactacg ctgatccaag ccttggtatt
    16801 gaatgggaaa atattgcaga agcagaagtt tcagaagcag ataaaaatca tccactactt
    16861 aaggatgtaa aacctttgaa aaaagaagat ttgtaaaaag gaaagaatat gactgaatac
    16921 aaaaatatta tcgtgacagg tggagctggc tttatcggtt ctaactttgt ccattatgtt
    16981 tacgagaact ttccagatgt tcatgtgaca gtcctagata agttgactta tgcaggtaat
    17041 cgtgccaata ttgaggaaat tttaggtaat cgtgttgagt tagttgttgg tgacattgct
    17101 gatgcggagt tggtagacaa gttggctgct caagcagatg ctatcgttca ttatgcagcg
    17161 gaaagccaca atgataattc gctcaatgat ccatcgccat ttattcatac taacttcatc
    17221 ggaacctata ctcttttaga agctgctcgt aagtatgata ttcgcttcca ccatgtatcg
    17281 acagatgaag tttatgggga tctcccttta cgcgaagatt tgccaggtca tggtgaagga
    17341 ccaggtgaga aatttactgc tgaaacaaaa tacaacccaa gctctccgta ctcatcaacc
    17401 aaggcagcct cagatttgat tgtcaaagcc tgggtgcgtt cttttggagt caaggcaacg
    17461 atttccaact gttcaaataa ctacggtcct tatcaacata ttgagaagtt tattccacga
    17521 caaatcacca atatcttgag cggtatcaag ccaaaacttt acggtgaagg taagaacgtt
    17581 cgtgactgga ttcataccaa tgaccattct tcaggagttt ggacaatctt gacaaaaggg
    17641 caaatcggtg aaacctactt gattggggct gatggtgaga agaacaataa ggaagttttg
    17701 gaacttatcc ttaaggaaat gggacaagct gcggatgcct atgatcatgt gactgaccgt
    17761 gcaggacatg accttcgcta tgcgattgat gctagcaagc tccgtgatga gttgggatgg
    17821 aaacctgaat ttaccaactt tgaagctggg ctcaaggcaa caatcaagtg gtatacagat
    17881 aaccaagaat ggtggaaagc agaaaaagaa gctgttgaag ccaattatgc taaaactcag
    17941 gagattatta cagtataaaa agcaggaaat agctgctttt tattgctata ttgggaagag
    18001 ttacatatta gaaaggtcta gagatgattt taattacagg ggcaaatggc caattaggaa
    18061 cggaacttcg ctatttattg gatgaacgta atgaagaata cgtggcagta gatgtggctg
    18121 agatggacat taccaatgaa gaaatggttg aaaaagtttt tgaagaggtg aaaccgactt
    18181 tagtctacca ctgtgcagcc tacaccgctg ttgatgcagc agaggatgaa ggaaaagagt
    18241 tggacttcgc catcaatgtg acggggacaa aaaatgtcgc aagagcatct gaaaagcatg
    18301 gtgcaactct agtttatatt tctacggact atgtctttga cggtaagaaa ccagttggac
    18361 aagagtggga agttgatgac cgaccagatc cacagacaga atatggacgc actaagcgta
    18421 tgggggaaga gttagttgag aagcatgtgt ctaatttcta tattatccgt actgcctggg
    18481 tatttggaaa ttatggcaaa aacttcgttt ttaccatgca aaatcttgcg aaaactcata
    18541 agactttaac agttgtaaat gaccagtacg gtcgtccgac ttggactcgt accttggctg
    18601 agttcatgac ctacctagct gaaaatcgta aggaatttgg ttattatcat ttgtcaaatg
    18661 atgcgacaga agacacaaca tggtatgatt ttgcagttga aattttgaaa gatacagatg
    18721 tcgaagtcaa gccagtagat tccagtcaat ttccagccaa agctaaacgt ccgctaaact
    18781 caacgatgag cctggccaaa gccaaagcta ctggatttgt tattccaact tggcaagatg
    18841 cattgcaaga attttacaaa caagaagtga gataagtagt agaatgattt tctagtctaa
    18901 taaaagaggc agataatgaa ctccaaagga gcttaaggtg tacgattatc ttgttgttgg
    18961 tgctggtctc tttggcgcat agctttggct cag
//
LOCUS       DAVHTH010000037        18381 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.037, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000037 DAVHTH010000000
VERSION     DAVHTH010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18381)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18381)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18381
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.037"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            complement(32..1711)
                     /locus_tag="VVR63_001417"
     CDS             complement(32..1711)
                     /locus_tag="VVR63_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEU6129430.1"
                     /translation="MAYTLKPEEVGVFAIGGLGEIGKNTYGIEYQDEIIIVDAGIKFP
                     EDDLLGIDYVIPDYSYIVDNIDRVKAVLITHGHEDHIGGIPFLLKQANVPIYAGPLAL
                     ALIRGKLEEHGLLRNAKLYEINHNTELTFKNLKATFFRTTHSIPEPLGIVIHTPQGKI
                     VCTGDFKFDFTPVGEPADLHRMAALGEEGVLCLLSDSTNAEVPTFTNSEKVVGQSIMK
                     IIQGIEGRIIFASFASNIFRLQQATEAAVKTGRKIAVFGRSMEKAIVNGIDLGYIKAP
                     KGTFIEPNEIKDYPAGEVLILCTGSQGEPMAALSRIANGTHRQVQLQPGDTVIFSSSP
                     IPGNTTSVNKLINIISEAGVEVIHGKVNNIHTSGHGGQQEQKLMLCLIKPKYFMPVHG
                     EYRMQKVHAGLAVDTGVEKDNIFIMSNGDVLALTADSARIAGHFNAQDIYVDGNRIGE
                     IGAAVLKDRRDLSEDGVVLAVATVDFKSQMILSGPDILSRGFVYMRESGDLIRQSQRI
                     LFNAIRIALKNKDASVQSVNGAIVNAIRPFLYENTEREPIIIPMILTPDEE"
     gene            complement(1713..1946)
                     /locus_tag="VVR63_001418"
     CDS             complement(1713..1946)
                     /locus_tag="VVR63_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HEU6129431.1"
                     /translation="MIYKVFYQETKERSPRRETTRALYLDIDASSELEGRITARQLVE
                     ENRPEYNIEYIELLSDKLLDYEKETGAFEITEF"
     gene            complement(2764..2916)
                     /gene="cibB"
                     /locus_tag="VVR63_001419"
     CDS             complement(2764..2916)
                     /gene="cibB"
                     /locus_tag="VVR63_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000977347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibB"
                     /protein_id="HEU6129432.1"
                     /translation="MMKNLNNYREISNKELQEIKGGFGVGVGIALFMAGYTIGKDLRK
                     KFGKSC"
     gene            complement(2918..3103)
                     /gene="cibA"
                     /locus_tag="VVR63_001420"
     CDS             complement(2918..3103)
                     /gene="cibA"
                     /locus_tag="VVR63_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000180803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibA"
                     /protein_id="HEU6129433.1"
                     /translation="MTNFDILDNQFLSLSENELSDIDGGLAPLVIFGVAVSWKAIAGG
                     TALIGSGLAAGYFLGGD"
     gene            3281..3964
                     /gene="tsaB"
                     /locus_tag="VVR63_001421"
     CDS             3281..3964
                     /gene="tsaB"
                     /locus_tag="VVR63_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HEU6129434.1"
                     /translation="MKVLAFDTSSKALSLAILEDKQVLAETTINIKKNHSITLMPAID
                     FLMASLDWTPKDLDRIVVAEGPGSYTGLRIAVATAKTLAYTLNIELVGMSSLLALVPH
                     QQEGLFVPLMDARRNNVYAGFYENAKPVMAEAHLSFEEVLEKVKGTSQVTFVGEVAPF
                     VEQIQEHLPRTNYKETLPNAANLALLAWDKEADSLHDFVPNYLKRVEAEENWLKNHTE
                     SGESYIKRL"
     gene            3961..4398
                     /gene="rimI"
                     /locus_tag="VVR63_001422"
     CDS             3961..4398
                     /gene="rimI"
                     /locus_tag="VVR63_001422"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HEU6129435.1"
                     /translation="MIEIKRIQQQPDLAQAIYAVMAAVYLVSPWTLEQIQADLSQDQT
                     WYVLAYDGAEVIGFLAVQENIFEAEVLQIAVKGAYQGQGIASALFAQLPTDKEIFLEV
                     RKSNQRAQAFYKKEKMAVIAERKAYYHDPVEDAIIMKREIDEG"
     gene            4388..5398
                     /gene="tsaD"
                     /locus_tag="VVR63_001423"
     CDS             4388..5398
                     /gene="tsaD"
                     /locus_tag="VVR63_001423"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HEU6129436.1"
                     /translation="MKDRYILAFETSCDETSVAVLKNDDELLSNVIASQIESHKRFGG
                     VVPEVASRHHVEVITACIEEALAEAGITEEDVTAVAATYGPGLVGALLVGLSAAKAFA
                     WAHGLPLIPVNHMAGHLMAAQSVEPLEFPLLALLVSGGHTELVYVSEAGDYKIVGETR
                     DDAVGEAYDKVGRVMGLTYPAGREIDELAHQGQDIYDFPRAMIKEDNLEFSFSGLKSA
                     FINLHHNAEQKGESLSTEDLCASFQAAVMDILMAKTKKALEKYPVKTLVVAGGVAANK
                     GLRERLAAEITDVKVIIPPLRLCGDNAGMIAYASVSEWNKENFAGWDLNAKPSLAFDT
                     ME"
     gene            complement(5438..6744)
                     /locus_tag="VVR63_001424"
                     /pseudo
     CDS             complement(5438..6744)
                     /locus_tag="VVR63_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011680908.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(7020..7371)
                     /locus_tag="VVR63_001425"
                     /pseudo
     CDS             complement(7020..7371)
                     /locus_tag="VVR63_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(7478..7771)
                     /locus_tag="VVR63_001426"
                     /pseudo
     CDS             complement(7478..7771)
                     /locus_tag="VVR63_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            8014..9220
                     /locus_tag="VVR63_001427"
                     /pseudo
     CDS             8014..9220
                     /locus_tag="VVR63_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200043.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
     gene            9213..10166
                     /locus_tag="VVR63_001428"
     CDS             9213..10166
                     /locus_tag="VVR63_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU6129437.1"
                     /translation="MDRNIDQELVSIIIPTHNRYESLIRAVKSCLHQSYKNIEVIIID
                     DNYSNVNLRNKIIHQFGYTNHRIKLILSNEDLGATNARNIGIKNSRGKYISFLDDDDE
                     YMSDRILKLMACFKKSRMKNLALVYSYGIIIYPNGTREEEKTDFVGNPLFVQMVHNIA
                     GTSFWLCKKEVLELINGFEKIDSHQDGVVLLKLLAQGYQIDIVREFLVNYYAHSKENG
                     ITGVTQKTINADEEYYNYCRKYFNLLSFNERILVTKKYYSLNIKRLLLIGDKCKALKV
                     IKKAREEKIFNEFLFLKYMLLYHFGFFYCIYDNYVQLKFRK"
     gene            10176..11792
                     /locus_tag="VVR63_001429"
     CDS             10176..11792
                     /locus_tag="VVR63_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6129438.1"
                     /translation="MYTIIKSNIKKFSLLTIFIVAGQLLLIYAATINALVLNELIAMN
                     LERFLKLSIYQMIVWCGIIFLDWVVKNYQVEVIQEFNLEIRNRVATDISNSTYQEFHS
                     KSSGTYLSWLNNDVQTLNDQAFKQLFLVIKGISGTIFAVVTLNHYHWSLTVATLFSLM
                     IMLLVPKIFASKMREVSLNLTNQNEAFLKSSETILNGFDVLASLNLLYVLPKKIKEAG
                     ILLKMVIQRKTTVETLAGAISFFLNIFFQISLVFLTGYLAIKGIVKIGTIEAIGALTG
                     VIFTALGELGGQLSSIIGTKPIFLKLYSINPIESNKMNDIEPNEVNRDFPLYEAKNIC
                     YKYGDKEILKNLNFCFQRNEKYLILGESGSGKSTLLKLLNGFLRDYSGELRFCGDDIK
                     KTSYLNMVSNVLYVDQKAYLFEGTIRDNILLEENYTDEEILQSLEQVGLSVKDFPNNI
                     LDYYVGDDGRLLSGGQKQKITLARGLIRNKKIVLIDEGTSAIDRRTSLAIERKILDRE
                     DLTVIIVTHAPHPELKQYFTKIYQFPKDFI"
     gene            12141..12569
                     /locus_tag="VVR63_001430"
     CDS             12141..12569
                     /locus_tag="VVR63_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001290269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6129439.1"
                     /translation="MSEIVEMSKKISDLNDKKEFHKKNCELRFQDSVLDNINSVPSTT
                     HLFSCLNIQTLVKIILYIFRYNSCMKIFNFRDKELIFFNKIVNGLIQNIEENLEDDIE
                     RILKYLYICLFNEIFIIKNKVNFFDDVEFNQTLSEFLDKL"
     gene            12581..13330
                     /locus_tag="VVR63_001431"
     CDS             12581..13330
                     /locus_tag="VVR63_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000069862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HEU6129440.1"
                     /translation="MSNNTKYIFLSPHLDDAIFSCGDYISKLTSEGEIVLVITIFSGY
                     PLSQQLQPSAKQFHKLCNLGKYPIEERKKEDRLACERLQCDFRHLSYYECLYRKDRNG
                     NFLYRHIYSELKNEDTLKNDIIKELLMHLDDKCVVYCPLSLGDHVDHVFVNSIGRALE
                     FMRYKVIYYEDFPYVSDSSMVSYMGKTKELKMYQEELDEKHYIDRISSILCYKSQILI
                     IWKSVEKLLNNIKELYLRNGAAYSIRFWIKK"
     gene            13343..14515
                     /locus_tag="VVR63_001432"
     CDS             13343..14515
                     /locus_tag="VVR63_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HEU6129441.1"
                     /translation="MNIAVIGLGHVGLAYALLFASKYKVVAYDIDSVKINNLKKGILP
                     SKNEELMKFFCENNLNITFFDTFSEIKNNIDYYIIALPTDYDEKIGSFNTYEIEQTVS
                     KILRVKPNGKIILKSTVPFGFSNKLKRLFDTKNIIFVPEFLREGCSIYDNLYPSRIVV
                     GDETVEGRKIAELFLSISTHSTANIKNVMLVSPTEAEAIKLFSNTFLALRVAFFNELD
                     SFAERRSLNAEVVIKGVCLDPRIGNFYNNLSFGFGGYCLPKDTKQLKKEFIEINAPVI
                     EAIDISNTNRKQFIVKQILERKPKIVGIYKLGMKYNSDNYKESAILSIINELLIVGIK
                     ILVYEPNLNVSIDNVIFEKNFELFTKQSDLIVANRWDRGLEAYKDKVYTRGIWIRD"
     gene            14911..15774
                     /locus_tag="VVR63_001433"
     CDS             14911..15774
                     /locus_tag="VVR63_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HEU6129442.1"
                     /translation="MIEKMELGEFYKELRLARKLKQSDVACDGLTASQLSKFELGQSM
                     LSADKLILAIQGINVTFDEFGHKLNNYQESPHMQIGRKVVDRFAHQDIAGLEQLLEEV
                     EQEQMAETYRRLNAIVIKDAIHSLDKSYPLAEEDSEFLTTYLYAIESWTWFELYLFCN
                     TLPFLSNQDLIFLSTSLLEKSKEFKELVHNRLYMKQGLLNIISELMERKLFSYIPIFE
                     AELESMLRPYDVFEKVLWQFLKKMSIFLQTKGSNQKEIEHFIQSLQVLENPQLIALFE
                     LRLQQYKKLID"
     gene            16060..16260
                     /locus_tag="VVR63_001434"
     CDS             16060..16260
                     /locus_tag="VVR63_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide pheromone VP1"
                     /protein_id="HEU6129443.1"
                     /translation="MLNLQFAETMELTEAELEIVYGGEFGNNAVIPAGAWGGFGTPWS
                     ITNFWKKNFNDRPDFDSDRRRY"
     gene            16327..16992
                     /locus_tag="VVR63_001435"
     CDS             16327..16992
                     /locus_tag="VVR63_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU6129444.1"
                     /translation="MKKIISHRYFIIVFLLVIADQKFSVLVLRSDLVTGLSDFAYYLS
                     DMMLNFLVVLFALIAMIWSGKWQKINSRKFKGSYLFYSFLALLAFVVWNFVTFFLFPP
                     TRNEISYQHAAPTFTGATAFLMYFFYPVIAGPIFEEIIHRGLVMTALEKGKKWGLDVL
                     GSAILFGVSHISNHGWVLTDFVFYMGGGLIFAVLFRMTKSIYWPIGLHIVYNGIGQLL
                     MLL"
     gene            17064..18290
                     /locus_tag="VVR63_001436"
     CDS             17064..18290
                     /locus_tag="VVR63_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEU6129445.1"
                     /translation="MKVFLQNRDFRQLTINQWISTLGDTIFYLAFLNYVADASFAPLA
                     ILLITISETLPQVLQIFLGVLADFQHHRVLKYTVISFTKFLLYSIVSLSLSGQSFSLL
                     LVTFICMINLLSDTLSYFSGAMLTPIFIRIIGQDHLAEAIGFKQSTVSLVKTISNILG
                     GVLLGILSIQFISLLNALTFLIAFLGILFIKTDLLKVEKTISYQEGLSVKSFCQHLLQ
                     SSKLIWNMNKVLLVLFIISTSQAVINVTVPVSTLFLRNQPFLNLQTGQSLALLSTFEL
                     SALIVGSLVSGYLQHTISIKTALYASLVIQLLLLVGFATVRFDWILIFSTLDAFFAGV
                     LSPRLQELVFKQIPEESMGAVQSSISAITVVLPSLFTISLVTIATSFGTLAVSFVLLL
                     FLLVAFVMLLNIRESI"
BASE COUNT         5708 a         2958 c         3769 g         5946 t
ORIGIN      
        1 gcaaggcgaa gctgacgtgg tttgaagagt attattcttc atctggtgtg aggatcatcg
       61 ggatgatgat cggttcacgt tcggtatttt catagaggaa ggggcgaata gcgttgacaa
      121 tggcaccatt gacagattgc acgctagcat ccttattttt cagtgcgata cgaatggcat
      181 tgaagaggat acgctggctt tggcgaatca agtcgccaga ctctctcatg tagacaaagc
      241 ctcggctgag gatgtctgga ccagatagaa tcatctgcga tttgaagtca acagttgcga
      301 ctgccagaac gacaccgtct tcagatagat cgcgacgatc tttgaggaca gctgcgccaa
      361 tttcaccgat acgatttcca tcgacataga tatcttgggc gttgaaatga cctgcgatac
      421 gagctgagtc agcagtaagg gcaagcacat cgccattgct catgataaag atattgtcct
      481 tctcaacacc agtatccact gctagtccag cgtggacttt ttgcatgcgg tattcaccgt
      541 ggacaggcat gaagtatttt ggcttaatca agcagagcat gagtttttgc tcttgctgac
      601 caccgtgtcc agatgtatgg atattgttca ctttaccgtg gataacttcg acaccagctt
      661 cagaaatgat gttaatcagc ttgttgacgc tagtagtgtt tccagggatg ggactagaag
      721 agaagataac ggtatcacct ggttgtaatt gtacttgacg gtgggttccg ttggcgatac
      781 gagagagggc tgccataggc tcaccctgac tacctgtaca gaggataaga acttctcctg
      841 caggataatc tttgatttca tttggctcga taaaggttcc cttaggagct ttgatgtagc
      901 caagatcgat tccgttgaca atggcctttt ccatagaacg accaaagacc gcaatcttgc
      961 gtccagtctt aacagcagct tctgttgcct gctggagacg gaagatattt gaggcaaagg
     1021 atgcaaagat gatacgtcct tcaatacctt ggataatctt cataatggac tgaccaacga
     1081 ctttttcaga gttggtaaag gttggtactt ccgcatttgt cgagtcagac aggagacaga
     1141 gcacaccttc ttcaccaagc gcagccatac gatgcaagtc cgcaggttct ccaactggag
     1201 taaagtcgaa cttaaagtcc cccgtacaga cgattttccc ttgaggagta tgaatgacaa
     1261 tccccaaagg ctctggaata gagtgagtcg ttctaaagaa agttgccttg agatttttaa
     1321 aggtcaactc ggtgttgtgg ttgatttcgt aaagtttggc gttgcgcaag aggccgtgtt
     1381 cttcgagttt cccacggatc aaagccaagg caagcggtcc agcgtagata gggacatttg
     1441 cttgcttgag taggaacgga atcccaccaa tgtggtcctc gtgtccgtgt gtgattaaaa
     1501 cagccttgac gcggtcgata ttgtccacga tgtaagagta gtcaggaatg acatagtcga
     1561 taccaagcaa gtcatcttct gggaatttaa tcccagcatc gacgatgata atctcgtctt
     1621 ggtattcaat tccgtaagtg tttttcccga tttctcctag accaccgatg gcaaaaacgc
     1681 cgacttcttc aggtttaaga gtgtaggcca tattagaact ccgtaatttc gaaggcgcca
     1741 gtttcttttt cgtaatcgag caatttgtca gacaagagtt cgatatattc gatattgtac
     1801 tctgggcgat tttcttcgac aagttggcga gcagtgatac ggccctcaag ttctgagctg
     1861 gcatcgatgt ctaggtaaag cgcgcgtgtt gtttcacggc gtgggctacg ttcttttgtt
     1921 tcttgataaa aaactttgta aatcatatag ttcctttcta tttacaggtc agcttattcc
     1981 aaacttttag cagatatttg cttgatttca ttccattttg tgtctagatt gaccttgatt
     2041 cgttacaatt atttcaatta taccacaaaa tgaaaaatta gtaaaagacg gaaacgagaa
     2101 agttaggggg caatttcttt ggtaagcgtt tacaaaaata aagaaaatgt attatgttga
     2161 taacggaagt gaaatttatt gcttgtcata attccatata gattttaagt caaggaggtt
     2221 gccctatgta taacttattt gcttttgcta tcggagttcg tttgttagct tttatcgttt
     2281 ttgttgcttg cgtttatgga ggaaatcttc catttgccaa actggaacga tgacaaacca
     2341 agttcttgtg gaaaattacc tttgtgactc tctactcgct ttttctcctc ctcgtgccct
     2401 atgtcgtttg gtttgtattt tactttggat taaatgctta gatgccctgc ttatgctggg
     2461 gttttttgtt tggggatgta gagatagtag atttacgaca cgaaaattcc accccatcta
     2521 tcaagatgag gtggtctttg catttttcta aaatgacatg acaatggaat tttcaaagct
     2581 tattattttt atgggagtca ttgttctgct caaaaataga gttgaagcat aaaaataaaa
     2641 caatacaaac agataaatcg aatggtaaag ggatagtagt aatgttcaaa tcattgagaa
     2701 tgctgagcaa actgtaagag atgaagacaa taaaatttat ccttctaaaa atgtgtttct
     2761 tatctagcat gacttaccaa actttttacg aaggtctttt ccaatggtat aacctgccat
     2821 aaataaagcg ataccaacac ctacaccaaa gccacccttg atttcttgca attccttatt
     2881 agaaatttca cgatagttgt tcaaattttt catcatatta atctcctcct aaaaaataac
     2941 cagctgccaa accagaacct ataagtgctg ttccacctgc aatagccttc caagatactg
     3001 ctactccaaa gataaccaag ggagcgagac cgccatcaat atctgataat tcattttcag
     3061 ataaggataa aaattgattg tcaagaatgt caaaatttgt cattgaactt tcctcctttt
     3121 ttcttgttca cttttatatt cggaaaagaa aaggaaaagt gagcattttt ttaaattatt
     3181 tttagttaag tgagggcact cttgtctggg ggcaaagaaa attcccatgt gccagctttt
     3241 gtagtataat agtaagcaga caaaaagata ggaatgtgtt atgaaagtat tagcttttga
     3301 tacgtccagc aaggctcttt ctctggctat tttagaggat aagcaggttc ttgccgagac
     3361 gacgattaat attaagaaaa atcacagtat tactcttatg cctgccatcg attttttgat
     3421 ggcaagtttg gattggacac caaaggattt ggaccgaatc gtggtagctg aagggccggg
     3481 tagctataca ggcttgcgaa ttgcggtagc aactgctaag accttagctt acaccctgaa
     3541 catcgagttg gttggtatgt cgagtctctt ggctctggtg ccccaccaac aagaaggttt
     3601 gtttgtcccc ttgatggatg cgcgtcgcaa taatgtttat gcaggatttt atgaaaatgc
     3661 caaacctgtc atggcagaag cgcacctatc ttttgaagag gtgctagaaa aagtcaaggg
     3721 tactagtcag gtaacctttg tcggagaagt tgcccccttt gtggagcaga ttcaagaaca
     3781 cttgccaagg actaattata aagaaacctt gcctaatgca gccaatcttg ctcttttagc
     3841 ttgggacaag gaagcagact ccttgcatga ttttgtgccg aattacctca aacgagtcga
     3901 ggctgaggaa aactggctca agaaccatac cgagtctggt gagtcctaca ttaaacgcct
     3961 atgatagaaa tcaagcgaat tcaacaacag cctgacctag ctcaagccat ctacgctgtt
     4021 atggcagctg tttacctagt cagtccttgg actctggagc aaatccaagc agacctgtcc
     4081 caagaccaga cttggtatgt tctggcttat gatggggcag aagtgattgg ttttctagct
     4141 gttcaggaaa atatctttga ggcagaagtc ttgcaaatcg ctgttaaagg agcttatcag
     4201 ggtcagggaa ttgcgtcagc cttgtttgct caattgccga cagataagga gattttcctc
     4261 gaagtcagaa agtcaaatca acgagcgcaa gcattttaca agaaagaaaa aatggcggtc
     4321 atcgctgagc gaaaggccta ctaccatgac ccagtcgagg acgccattat catgaagaga
     4381 gaaatagatg aaggatagat atattttagc atttgagaca tcctgtgatg agaccagtgt
     4441 cgccgtcttg aaaaacgacg atgagctctt gtccaatgtc attgctagtc aaattgagag
     4501 tcacaaacgt tttggtggcg tagtgcccga agtagccagt cgtcaccatg tcgaggtcat
     4561 tacagcctgt atcgaggagg cattggcaga agcagggatt accgaagagg acgtgacagc
     4621 tgttgcggct acctacggac caggcttggt cggagccttg ctagttggtt tgtcagctgc
     4681 caaggccttt gcttgggctc acggacttcc actgattcct gttaatcaca tggctgggca
     4741 cctcatggca gctcagagtg tggagccttt ggagtttccc ttgctagccc tcttggttag
     4801 cggtgggcac acagagttgg tctatgtttc ggaggcagga gattacaaga ttgttgggga
     4861 gacacgagac gatgcagttg gggaggctta tgacaaggtc ggtcgtgtca tgggcttgac
     4921 ctatcctgca ggtcgtgaga ttgacgagct ggctcatcag gggcaggata tttatgattt
     4981 cccccgtgcc atgattaagg aagataatct ggagttctcc ttctcaggtt tgaaatctgc
     5041 ctttatcaat cttcatcaca atgccgagca aaagggagaa agcctgtcta cagaagattt
     5101 gtgtgcttcc ttccaagcag cagttatgga cattctcatg gcaaaaacca agaaggcttt
     5161 ggagaaatat cctgttaaaa ccctagttgt ggcaggtggt gtggcagcca ataaaggtct
     5221 cagagaacgc ctagcagccg aaatcacaga tgtcaaggtt atcatccccc ctctgcgact
     5281 ctgcggagac aatgcaggta tgattgccta tgccagcgtc agcgagtgga acaaagaaaa
     5341 cttcgcaggc tgggacctca atgccaaacc aagtcttgcc tttgatacca tggaataaag
     5401 agtggctctt tgtcaagtgt agtgggtagg cgaaaagcta caatctggag agtacgaaat
     5461 tcgtactctc ttttttgatg ttcaaagtca tcaaaatccg ttttttaaaa ttgttaaagt
     5521 tccggaaacc aaaggctttg cgcttgataa ccttaatcaa attattggtc gcttcaagtt
     5581 tagcgttgga ataaggcagc ttaagtgcgt tgataatctt atctctatcc cttaaaaaag
     5641 tccaaaagac cgtttgaaaa agcggatgaa ccgttggcag ttcttgctca atcaatccaa
     5701 agaaatggtc ggcattcttc tcttgaaaat gaaagagcag gagttgatag agttcgtagt
     5761 gaacctgtaa tccctcagag taagaaagca gcttatctcg tacttcccga tgggttaagt
     5821 gcattcgaaa cgtgggctga tagaatcgtt tctgacagag cttgaagcta tcctggtgta
     5881 gtaaatcagt ccagtggact gatttagccc gagcctagaa acgaaaaagc gagggttcca
     5941 aaagcgcttg agcgcccgat actccaagga ttttcggtca aattggttca tgatttggat
     6001 tcgtactcgg ttcatagctc ggctcagatg ttggacaatg tggaagcggt caagaacaat
     6061 cttcgccttt ggaaagagtt gcttagcgag ccgataataa gggctgtaca tgtccatggt
     6121 gatgacctcg accagctccc gaacctctct ctgatagcgt tggaaatggt ttcgaatcac
     6181 cgcatgagtt cgcccgtcta aaattgcgag gatggatttg gactcaaaat cttgggcaat
     6241 gaagctcatt ttgctctttt tgaagctata ctcatcccaa ctcataactt ttggcaactt
     6301 ggtccaatcg gtttcaaact taaattccct cagttttcgg atgacggtgg aagttgagac
     6361 cgccaatctg tgggcaatct cagtcataga ctgcttttca aggaggagct gagcgatttt
     6421 ttgtctcacc atgttggaaa tctggcaatt tttcttgaca atggatgttt gagaaacgac
     6481 caccttaagg caattcttgc actgaaagcg gcgctttttg agatgtagta ccgtgggtaa
     6541 accctgacag tcgagaagcg gaattttaga ggctttctgg aagtcgtatt tgatcatctt
     6601 cccttgacaa tgaggacaag gaggagcggg ggaatccaac tttgcctgaa cgactagatg
     6661 ggtttggtat ttcagaacag acaagatttt gatatttttg tctttcaatc cgagcaaatc
     6721 tgtggtattc ttaagttgtt ccatatgaac cctttctaat gagttggtta gacgcttttc
     6781 attataggtc atatggggct ttttttctac aagaaacgac cctataattc ctggggtggg
     6841 attacccact acagaaatta tagagccaaa acattccaaa gtcttgtctg actctggaat
     6901 gttttctgtt cacagttgtt ttgtaactgc ctaataagta accgcgctat aacgaggtat
     6961 ctaccgagat tgtcaattct ccagtatact gttataaaaa acaaaactgg aggatttttt
     7021 tatgtccccc catcgtccca tcgactgttc cgtagctgcc caataacgga gtatagtcgg
     7081 ctgaaacaag aataggacaa aagtgcctca agaaaagcat cgtaatttga caatattatt
     7141 ctgagatgtt tttgatgtaa gcccatattt tctcaatggg attatactcg ggtgaatagg
     7201 taggaagtgg taacagtcta tgccctgctc cttacacatg ttcattctgt gaaaccttgc
     7261 attgtccata atgataaggg atggtgtatc taaagtaggt agtaagaatt tttggaagca
     7321 agcttcgaaa aagtcactcg tcatcgtatc tttataggtc atcggagcca tagtatattg
     7381 aaacaaaaaa gggcattagt acttctataa cagtatcgca atctctggtg tgcgttgtct
     7441 cgatcttaat tcaaataatt atatcttctt ccagagagac taactgcctg ctcaaggctc
     7501 gatcatattc gagataaaaa taggtctcaa cccctgtctc ataaatataa ataggagtca
     7561 ggtagcttaa gtgattcaat tctttaagga accgatttac tttttctggg tcttgttcgc
     7621 agtaggtaca gctctttttt agactatatc ccatagcctt tagagcgtaa tgaatagttg
     7681 ttggaggaca gttgaattca gcagctattt cagtcaaata agcatcggga tgagtttcaa
     7741 tatagatctt taatttatct ctatcaactt tttcaattaa tagtggaagt tttcttaaag
     7801 ttagtgtgtt gaaacgtttt tatacagtgc taaaatttga agtgtagtgc agatgtattt
     7861 gtaatagtat tatagcaatt ctttggagaa ggtcgagaca agagaaaata ggtatctttg
     7921 agatataagc atgatttact ataaaattat tgagttattc ataaaaattt ctctatcaaa
     7981 tatcataatg cgtcgtttaa ggagatggtt acaatgcaat atagttgtgg aaaaataaat
     8041 attaatatcc ctgatggata tggagacatt aaggatatag tgttttcggc tcatattata
     8101 gttaggtata ataatggaca ttgtggaggt atagatccgc atataattgg actttgtaaa
     8161 aagcagatca gaaggatgtc tctatatcct attttgataa tcgtatctag agattcaaag
     8221 gttattgatg attataaaaa tttagatatt gcctatgttg attgtactca atgttcaaat
     8281 aattttgaaa ctgccttaca cgttaaaaat attttaaaat tattaaaaat ccaacttata
     8341 cactgtcatg gctactcaac taattatttt ttatatatgt taaaaaaact tgacaagaat
     8401 ggatttggaa aggttaagac agtgataaca tgccatggat gggttgaata taacttaaaa
     8461 aagaaattct tgacttattt tgatttttgg acatattcta tgggagatgc ttttatttgt
     8521 gtatctgaaa ctatgaaaaa aagattggag agtataataa aaaaataaga agatagttgc
     8581 aataaataac ggaattaatg tatcaaatag cgatttagat gtagtaggtg ttcaagactt
     8641 taaaaaagaa ttttgtattc caaataacaa aaaaatcatt tgttatgttg gaaggttgga
     8701 tccagaaaaa aggccggata gattccttga atttgcagaa aaattatttt tagtcagaga
     8761 agatgtgatt tttattatgg ctggaaatgg tagtatgtgg gctgctttga aagaaaaaat
     8821 ttgccatttg aaatgtagag ataatttcag gttacttggt gaaatctatc cagctactat
     8881 agtttaccaa atatcggatt tattgtatat tccttctgat acagaaggaa tacctatgtg
     8941 tgttttagag tcaatgtcac aaggaactcc ggttttagct agtaatgttg gcgggttaag
     9001 tgaaattatt gaacataggg ttgatggatt tttatttgag aaggaagatg ttgagggagt
     9061 gtgtgcttgt gctaattttt tactcaatga ttctgagtat ttgaaatata taggtgagaa
     9121 tagtaaatca aaaataagaa aacatttttc tgtgcaaaaa atgtttgtag aaaccatgag
     9181 agtatatgat gaattattag agaagagtag tcatggatag gaatatagat caagaattag
     9241 taagtattat aataccaaca cataataggt atgaatctct gattagagct gtgaaaagtt
     9301 gtttacatca aagttataaa aatatcgaag ttataattat tgatgataat tatagtaatg
     9361 taaatttaag aaataaaatt atccatcaat ttggctatac caatcataga attaagttaa
     9421 ttttaagtaa tgaagattta ggtgcaacta atgccagaaa cataggtatc aaaaattcta
     9481 gaggtaagta tatatcattt ttagacgatg atgatgaata tatgtcagat cgaattttaa
     9541 agttgatggc ttgttttaaa aagagtagaa tgaagaattt agctttagtt tatagttatg
     9601 gaataataat ttatccaaat ggtacacgag aagaggagaa gaccgatttt gttggaaatc
     9661 ccttgtttgt tcaaatggtt cacaatatag caggtacgtc attttggttg tgtaaaaaag
     9721 aggtgctaga attaattaat ggttttgaga aaatagattc acatcaggac ggtgttgttt
     9781 tattaaaact acttgctcaa ggataccaaa ttgatatagt gcgagaattc ttggtgaatt
     9841 actacgctca cagtaaagaa aacggtatca ctggagtgac acaaaaaaca attaatgcag
     9901 atgaagaata ttataattac tgtaggaaat attttaattt attgagtttc aacgagagaa
     9961 tattggttac aaagaaatat tattctttaa acataaagcg gttactatta ataggagaca
    10021 aatgcaaggc tttaaaagta atcaagaagg caagagaaga aaaaattttt aacgaatttc
    10081 tttttttgaa atatatgtta ttatatcatt ttggtttttt ctattgtata tatgacaact
    10141 atgttcaatt aaaatttaga aagtgagaaa ctattgtgta tactattata aaatcaaata
    10201 taaaaaaatt tagtttatta acgatattta ttgttgctgg tcaattattg ctaatttatg
    10261 cagcaactat taatgctctg gtgttgaatg aattaattgc gatgaattta gagcggtttt
    10321 tgaaattgtc aatctaccaa atgattgtct ggtgtgggat aatattcctt gactgggtag
    10381 tgaaaaatta tcaggttgaa gtgatccaag agtttaatct agagattcga aatagagttg
    10441 ccacagacat ctctaactct acctatcaag aatttcatag taaatcatca ggaacatatc
    10501 tttcgtggct aaataatgat gttcagactt taaatgatca ggcttttaaa caactttttt
    10561 tagtaataaa aggaatttct ggtactatat ttgcagttgt gactcttaat cactatcatt
    10621 ggtcattgac tgtagccacc ttgttttcat taatgattat gctacttgta ccaaaaatct
    10681 ttgcatcgaa aatgcgagaa gttagtctaa atttaactaa ccaaaatgaa gcttttttaa
    10741 aatctagtga gactatattg aatggatttg atgtgttagc atccttgaat cttttatatg
    10801 tattgcctaa gaaaattaaa gaagcaggaa ttttattaaa gatggttata caaagaaaga
    10861 caactgtaga aacgttagca ggcgctatta gcttctttct caatattttt tttcagatat
    10921 ctctcgtttt tttaacaggc tatcttgcaa taaaaggaat agtgaaaatt ggtactattg
    10981 aagcaatagg agcactaaca ggtgttattt ttacagcgct aggtgaatta ggaggtcaat
    11041 tatcctctat tattggtacg aagcctattt ttttaaaatt gtattcaatt aatccaattg
    11101 agtcaaataa aatgaatgat atcgaaccaa atgaggtgaa tagagatttt ccgttatatg
    11161 aagcaaaaaa tatttgctat aagtatggag ataaagaaat attaaaaaac ttaaattttt
    11221 gttttcaacg taatgaaaag tatttaattt taggtgaaag tggaagcggg aaatctacat
    11281 tattaaaatt attgaatggc tttttgagag attatagtgg agaattgcga ttctgcgggg
    11341 atgatataaa aaaaacctcc tatttaaata tggtttcgaa tgttctatat gtagatcaaa
    11401 aagcttattt gtttgaaggt acgattagag ataatatttt attggaagaa aattatactg
    11461 atgaagaaat actacagtct ttagagcaag ttggtttgag tgtaaaagat tttcctaata
    11521 acattttaga ttattatgtt ggtgatgatg ggagattact gtcaggaggg cagaaacaaa
    11581 aaattacttt agctagaggg ctaattagaa ataagaaaat agtattaatt gacgagggaa
    11641 cttctgctat cgataggaga acttcgttag cgattgaacg taagatatta gatagagagg
    11701 atttgactgt cattattgtt acccatgctc cgcatccgga acttaaacaa tattttacta
    11761 agatatatca atttccaaag gattttattt aagaatatag gggagggaaa catgagattc
    11821 tattgtgaag cttatgaggt aattactgaa gagaaaaaag tatactttaa tgatattgag
    11881 ttagaagtta agtattcctc tgtcgaagaa ttgtttataa tatgtgagaa attattagat
    11941 aagaaaaaag tatcattttt ttatgtagat gagaaaccct taaggtatct gttatttgac
    12001 tatatatttc tactagttct agctaaaaaa atatcccaat cttatgaact gcaccccaaa
    12061 agttagattt attctgtcta acttttgggg tgcagttcat tttgcatagt tttggcattc
    12121 atcctagata tccatataaa atgtctgaga ttgttgaaat gtctaaaaaa atatcagatc
    12181 taaacgataa aaaagaattt cacaaaaaga actgtgagtt gaggtttcaa gatagtgttc
    12241 ttgataacat aaatagtgtc ccgagtacaa ctcatttatt tagttgttta aatattcaaa
    12301 cattagtaaa aattatttta tatatttttc gatacaacag ttgtatgaaa atatttaatt
    12361 ttagagataa agagcttatc ttttttaata agattgtaaa tgggctgata caaaatattg
    12421 aggagaattt agaggatgat attgaaagga tattgaaata tttatatata tgtttattta
    12481 acgaaatatt cattattaag aataaggtga atttttttga tgatgtggaa tttaatcaga
    12541 cacttagtga gtttttagat aaattgtaga gggaatggtt atgagtaaca atactaagta
    12601 tatcttttta tctccacatt tagatgacgc aattttttcc tgtggtgatt atatttcaaa
    12661 attaacttca gaaggagaaa ttgtacttgt tattactata ttttctggtt accctttgag
    12721 ccaacagcta cagccctctg ctaagcaatt tcataagttg tgtaaccttg ggaaatatcc
    12781 gattgaagaa aggaagaaag aagacaggtt agcttgtgaa cgtctacagt gtgattttag
    12841 acacttatcg tactatgaat gtctctatag gaaagataga aatggcaatt ttctataccg
    12901 tcatatctat agtgaattaa aaaatgagga cacattaaag aatgatatca taaaagagct
    12961 gttaatgcat ttagacgaca aatgtgtcgt atattgtccg ctttcacttg gtgaccatgt
    13021 tgatcatgtt tttgtgaata gtattggaag ggcgcttgaa tttatgcgtt ataaagtaat
    13081 atattatgag gacttcccat atgtaagtga tagtagtatg gttagttata tgggaaaaac
    13141 taaagaatta aaaatgtatc aagaggaact tgatgaaaaa cattatattg atagaatatc
    13201 atcaatattg tgctataaat ctcagatttt gataatctgg aaatcagttg aaaaactttt
    13261 aaacaatatt aaagagttgt atttaaggaa tggggcagct tattctatta gattttggat
    13321 taagaaataa ggaagtagtt ttatgaatat agcagtaatt ggtttggggc atgttgggct
    13381 ggcctacgcg ttactatttg catctaaata taaagttgtt gcatatgata tagattctgt
    13441 aaaaataaat aatttaaaaa agggcattct tccatctaaa aatgaagagc ttatgaagtt
    13501 tttttgcgag aataacttaa atattacttt ttttgataca ttttctgaaa ttaaaaataa
    13561 tattgattat tatattattg cgcttccgac agattatgat gagaaaattg gtagttttaa
    13621 tacatatgaa atcgaacaaa cggtatcgaa gattctgagg gtaaaaccta atggaaagat
    13681 tattttaaag tcaacagttc cgttcggctt ttcaaacaaa ttaaaaaggc tgtttgatac
    13741 aaaaaatatc atttttgtcc ctgaattttt gagagaaggt tgttctatat atgataattt
    13801 atatccaagt cgcatagttg ttggagatga gacagttgaa ggaagaaaaa ttgcagagtt
    13861 gttcctttcg attagtactc atagtactgc caatattaaa aatgttatgt tagtttctcc
    13921 tactgaagca gaagcaatta agcttttttc taacacattc ttagctctcc gtgttgcttt
    13981 ttttaatgaa ctagattctt ttgctgagag gagaagttta aatgctgaag ttgtaataaa
    14041 aggtgtttgt ttagatccaa gaattggaaa tttttataat aatctttctt ttggatttgg
    14101 aggatattgt cttcccaaag atactaaaca attaaaaaaa gaatttatag aaataaatgc
    14161 cccagtgata gaagcgattg atatttcaaa cacaaataga aaacagttca tagttaaaca
    14221 aatattggaa cgaaagccaa agatagtagg aatatataaa ttggggatga aatataattc
    14281 agataattac aaagagtcag ctattttaag tataattaat gaactattga ttgtcggtat
    14341 aaaaatttta gtatatgaac caaatttaaa cgttagtata gataacgtaa tttttgaaaa
    14401 gaattttgaa ctatttacaa aacaaagtga tctaattgtt gcaaatagat gggatagggg
    14461 ccttgaagct tataaagata aagtttacac aagggggatc tggataagag attaactatt
    14521 gatattaaaa aggcaataat ttataaaatt tgtacaaaaa aatgttaaat tttcacattt
    14581 tcatagtata ctgtttaata gaaagtaggt tctttgtaac cgctccatta taaaatcctt
    14641 tcactcttcc ggtatactat taggaaaaac ataactggag gatattttga gctcacacct
    14701 catcgttcca gtggctgttc cccaagctcg tgtactgccc aaaaaagtta gacattctat
    14761 ttagaacgag gattgagttc tgtattgtac aaggctcggt ccttttagag tcagcttaag
    14821 gctggctttt ttattttttc taactatcag aatattttga caaatgaaca caaataatga
    14881 tataatatgc aaaagctagg aggtggtagg atgattgaaa aaatggaatt gggggaattt
    14941 tacaaggaat tacgtttggc gagaaagctc aagcagtcag atgtggcttg tgacgggcta
    15001 acagcttctc agttgtccaa gtttgagcta gggcagtcca tgttgtctgc tgataagctc
    15061 atattagcca tccaagggat caatgtgacc tttgatgagt ttgggcacaa gctcaacaac
    15121 tatcaagaat ctccacatat gcagattggt agaaaggttg tggatcgctt tgctcatcaa
    15181 gatatagctg gcttagagca actgttggag gaagtcgagc aagaacagat ggcagagact
    15241 tatcgtcgtt tgaatgctat tgtaatcaaa gatgccatcc actcactaga taaaagctac
    15301 ccactagcag aggaggatag cgagtttttg accacctatc tctatgctat cgagtcttgg
    15361 acctggtttg aactctatct cttttgcaat actctgccct tcttgagcaa tcaagatctg
    15421 atctttttat caacctcctt actcgaaaaa tccaaagaat ttaaagagtt agtacacaat
    15481 cgattgtata tgaagcaagg actcttaaat atcatctcag agctcatgga gcgcaaactt
    15541 ttttcttata tcccaatctt tgaagccgag ctggagagta tgctccgtcc atacgatgtt
    15601 tttgagaaag tgttgtggca gtttttaaag aagatgagca ttttccttca aactaaggga
    15661 agcaatcaaa aagagattga acactttatc caatctctgc aagtattaga aaatccacaa
    15721 ttaatagccc tttttgaatt gcgtttgcag caatacaaaa agcttatcga ttagttagaa
    15781 atggcaaaat aataataatc tcagcaacga ttttcaataa tgttaaaatt tgtttcttca
    15841 tatttctcca ctcctcatta gtagtaactt tattatacca gagaagtaat caaattcacc
    15901 aaaatcgcaa atctgaaatt tctataagaa aaaatatcaa atatgcgatt ttctaaaata
    15961 agccaatttt cgtgttatac tgtacttgta aagcacttga agcaaatcct aggtcgcaga
    16021 agtggtttac aaatgaagat aattgaagga gtgtaaaaga tgttaaattt acaatttgca
    16081 gaaacaatgg aattgacaga agctgagttg gagatagttt atggagggga atttgggaat
    16141 aatgctgtta tcccagccgg tgcttgggga gggttcggga caccttggtc aatcactaat
    16201 ttctggaaga aaaattttaa cgatagacct gactttgatt ctgaccgccg tcgttattaa
    16261 tatccaaagc ccttgccttt tcttgggtag gggctgtctt tatttcatag tataggagga
    16321 aatagaatga aaaagataat ctcacaccgc tactttatta tagtttttct actagttatt
    16381 gctgaccaga agttcagtgt tctagtttta cgcagcgacc ttgttactgg gctatctgac
    16441 tttgcctatt atctgtcgga tatgatgttg aattttcttg tggttttatt tgctcttatt
    16501 gctatgattt ggtcggggaa atggcagaaa atcaatagta gaaagtttaa aggatcctat
    16561 cttttctatt ccttcctagc tctgcttgct tttgttgttt ggaatttcgt tacctttttt
    16621 cttttcccac ctactcgaaa tgaaatttct tatcaacatg ctgctccgac ttttacaggg
    16681 gctacagcat ttttgatgta ttttttctat cctgtgattg caggtcccat ttttgaagag
    16741 ataatccatc ggggattggt gatgacagct ctggaaaaag gaaagaaatg ggggctagat
    16801 gtacttggct ctgctatttt atttggggtc tcgcacatta gtaatcacgg ttgggtcttg
    16861 acagactttg tcttctatat gggtggaggt cttatatttg cagtcttatt tagaatgaca
    16921 aagtcaattt attggcctat tggactgcat atagtctaca atggtattgg tcagcttttg
    16981 atgttactgt aattttggtt gttagtagta tcgcggtcta ttcttgggga aagattccca
    17041 tttgaactta agaaggagtt gtaatgaaag tatttcttca aaatagagat tttaggcaat
    17101 taactatcaa ccagtggatt tcaacgcttg gggatacgat tttttatctg gccttcctga
    17161 attatgtggc agatgcgtct tttgcccctt tggcgatttt acttatcacg atttcagaaa
    17221 cccttcccca agttctacaa atctttctgg gagttttggc ggattttcaa catcatcgtg
    17281 tcttgaaata cacagtcatt agttttacaa aatttttgct ttactctata gtgtccctat
    17341 cgctttcagg gcagtctttt tccttgttgc tagtaacctt tatttgtatg attaacctct
    17401 tgtctgacac attgagttat ttttcaggcg ccatgctcac tccgattttc attagaatta
    17461 ttgggcaaga tcatctggca gaagctattg gatttaaaca gtcaactgtt agtttagtga
    17521 aaacaatcag taatatccta ggaggagtct tactaggtat tctatccatc cagtttattt
    17581 ccttactgaa cgctcttacc tttttaatcg catttttagg tatcctcttc ataaaaactg
    17641 acctcttgaa agtagaaaaa acgattagct atcaagaagg actctctgta aaatcctttt
    17701 gccagcattt gctccaatca tcgaaattga tatggaatat gaataaggtg ctcttggttt
    17761 tgtttattat ctctactagt caagcagtga taaatgttac agttcctgtc tctactctat
    17821 ttttgaggaa tcaacccttt ttgaatttac aaacaggtca atctcttgcc ttgctatcca
    17881 cttttgaact gtcagccctg attgtcggaa gccttgtaag tggctatctg caacatacca
    17941 tttccataaa aacagctctc tatgcctcac ttgtcatcca gttgcttctt ctagtaggat
    18001 ttgccacagt tcgttttgac tggattctca tctttagtac cttggatgcc tttttcgcag
    18061 gtgttctctc tcctagattg caagaactcg tctttaaaca aatacctgag gagtcaatgg
    18121 gagcagttca atcttctatc agtgccatta cggttgtttt acctagctta tttacaatat
    18181 ctttggtaac cattgctact agctttggaa ctctggcagt tagctttgtt ttattgctat
    18241 ttcttctagt tgcctttgtt atgcttctga atattcgtga aagtatttag tggagaattt
    18301 ctataatata tgtttgagac tggattgcca gtctttttat gatggtcaaa atcaacagac
    18361 tttttctctt ttctgaatgt g
//
LOCUS       DAVHTH010000038        17657 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.038, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000038 DAVHTH010000000
VERSION     DAVHTH010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17657)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17657)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17657
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.038"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            331..1407
                     /locus_tag="VVR63_001437"
     CDS             331..1407
                     /locus_tag="VVR63_001437"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000542485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HEU6129446.1"
                     /translation="MGYTVAVVGATGAVGAQMIKMLEESTLPIDKIRYLASARSAGKS
                     LKFKDQDITIEETTETAFEGVDIALFSAGGSTSAKYAPYAVKAGVVVVDNTSYFRQNP
                     DVPLVVPEVNAHALDAHNGIIACPNCSTIQMMVALEPVRQKWGLDRIIVSTYQAVSGA
                     GMGAILETQRELREVLNDGVKPRDLHAEILPSGGDKKHYPIAFNALPQIDVFTDNDYT
                     YEEMKMTKETKKIMEDDSIAVSATCVRIPVLSAHSESVYIETKEVAPIEEVKAAIASF
                     PGAVLEDDVVHQIYPQAINAVGSRDTFVGRIRKDLDAEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPTAELKFELK"
     gene            1463..2398
                     /gene="dapA"
                     /locus_tag="VVR63_001438"
     CDS             1463..2398
                     /gene="dapA"
                     /locus_tag="VVR63_001438"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HEU6129447.1"
                     /translation="MSYQDLKECKIITAFITPFHEDGSINFDAIPALIEHLLAHHTDG
                     ILLAGTTAESPTLTHDEELELFAAVQKVVNGRVPLIAGVGTNDTRDSIEFVKEVAEFG
                     GFAAGLAIVPYYNKPSQEGMYQHFKAIADASDLPIIIYNIPGRVVVELTPETMLRLAD
                     HPNIIGVKECTSLANMAYLIEHKPEEFLIYTGEDGDAFHAMNLGADGVISVASHTNGD
                     EMHEMFTAIAESDMKKAAAIQRKFIPKVNALFSYPSPAPVKAILNYMGFEAGPTRLPL
                     VPAPEEDAKRIIKVVVDGDYEATKATVTGVLRPDY"
     gene            complement(2445..3818)
                     /gene="mnmE"
                     /locus_tag="VVR63_001439"
     CDS             complement(2445..3818)
                     /gene="mnmE"
                     /locus_tag="VVR63_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002906470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HEU6129448.1"
                     /translation="MITREFDTIAAISTPLGEGAIGIVRLSGTDSFAIVQKIFKGKDL
                     NKVASHTLNYGHIIDPLTGKVMDEVMVGAMKSPKTFTREDIIEINTHGGIAVTNEILQ
                     LAIREGARLAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMNIAVKQLDGSLSD
                     LINNTRQEILNTLAQVEVNIDYPEYDDVEEATTAVVREKTMEFEQLLTNLLRTARRGK
                     ILREGISTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNINGVPLKLI
                     DTAGIRETDDIVEQIGVERSKKALKEADLVLLVLNASEQLTAQDRQLLEISQDTNRII
                     LLNKTDLPETIETSKLPEDVIRISVLKNQNIDKIEERINNLFFENAGLVEQDATYLSN
                     ARHISLIEKAVESLQAVNQGLELGMPVDLLQVDLTRTWEILGEITGDAAPDELITQLF
                     SQFCLGK"
     gene            complement(3954..4136)
                     /locus_tag="VVR63_001440"
     CDS             complement(3954..4136)
                     /locus_tag="VVR63_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005589823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HEU6129449.1"
                     /translation="MPFVRIDLFEGRTLEQKKALAKEVTEAVVRNTGAPQSAVHVIIN
                     DMPEGTYFPQGEMRTK"
     gene            4259..4849
                     /locus_tag="VVR63_001441"
     CDS             4259..4849
                     /locus_tag="VVR63_001441"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000068157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HEU6129450.1"
                     /translation="MAQLYYRYGTMNSGKTIEILKVAYNYEEQGKGVVIMTSALDTRD
                     GVGYVSSRIGMKRPALAIEETTDIFGYIRDLPEKPYCVLVDEAQFLKRHHVYDLARVV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLLADKIDEIKTICQYCKKKATMVLRTQDGL
                     PVYDGEQIQIGGNETYISVCRKHYFAPEINKENEEK"
     gene            4846..5925
                     /gene="prfA"
                     /locus_tag="VVR63_001442"
     CDS             4846..5925
                     /gene="prfA"
                     /locus_tag="VVR63_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HEU6129451.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSKEEASNR
                     DTVIAYREYKQVLQNIVDAEEMIKESGGDADLEEMAKQELKDAKAEKEEYEEKLKILL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAEAQGWRFEVMEASMNGVGG
                     FKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRVDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNREKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEVVDALVLYDQTQKLEELNK"
     gene            5925..6764
                     /gene="prmC"
                     /locus_tag="VVR63_001443"
     CDS             5925..6764
                     /gene="prmC"
                     /locus_tag="VVR63_001443"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HEU6129452.1"
                     /translation="MKLAQLFSNFEEELIRQGEEAESLSFVYRSLKNLSFTDFIFALQ
                     QEVTTEEEKQFVEDIYQQLAAHKPAQYIIGQADFYGMHLKVDERVLIPRPETEELVEL
                     ILTENLETNLSVLDIGTGSGAIALALAKNRPDWSVTAADVSQEALELASENASDQNLN
                     IFFKKSDCFAEISEKYDIIVSNPPYISREDESEVGLNVLHSEPHLALFADEDGLAIYC
                     RIAEDAKDYLKDGGKIYLEIGYKQGQSVPELFRKHLPEKKVRTLKDQFGQNRMVVVDD
                     GQD"
     gene            6748..7350
                     /locus_tag="VVR63_001444"
     CDS             6748..7350
                     /locus_tag="VVR63_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HEU6129453.1"
                     /translation="MMDRIRQELENGGAVVLPTETVYGLFAKALDEKAVDHVYQLKRR
                     PRDKALNLNIASFEDILHFSKNQPTYLQKLVETFLPGPLTIILEANDRVPYWVNSDLA
                     TIGFRMPSHPITLDLIRETGPLIGPSANISGQASGVTFEQILKDFDQEVLGLEDDAFL
                     TGQDSTIVDLSGDKVKILRQGAIKREDILARLPEISFEEA"
     gene            7352..7783
                     /locus_tag="VVR63_001445"
     CDS             7352..7783
                     /locus_tag="VVR63_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000942930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6129454.1"
                     /translation="MLRDLQETDVKAICDINQEALGYTFSPEETASQLARLSQDSHHF
                     LLGYEDAANHVLLGYVHAEVYESLYSKAGFNILALAVSPQAQGQGIGKSLLQGLEEEA
                     KRCGYGFIRLNSANHRLGAHAFYEKVGYTCDKMQKRFIRIF"
     gene            7845..9101
                     /locus_tag="VVR63_001446"
     CDS             7845..9101
                     /locus_tag="VVR63_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HEU6129455.1"
                     /translation="MIFDKDDFKAYDADLWNAIAKEEERQQNNIELIASENVVSKAVM
                     AAQGSILTNKYAEGYPGRRYYGGTDVVDVVETLAIERAKEIFGAKFANVQPHSGSQAN
                     CAAYMSLIEPGDTVMGMDLASGGHLTHGAPVSFSGQTYNFVSYSVDPETELLDFDAIL
                     KQAQEVKPKLIVAGASAYSQIIDFSKFREIADAVGAKLMVDMAHIAGLVAAGLHPSPV
                     PYAHITTTTTHKTLRGPRGGLILTNDEELAKKINSAIFPGIQGGPLEHVVAAKAVSFK
                     EVLDPAFKEYAANVIKNSKAMADVFLQDPDFRIISGGTENHLFLVDVTKVVENGKVAQ
                     NLLDEVNITLNKNSIPYESLSPFKTSGIRIGAAAITARGFGEEESRKVAELIIKTLKN
                     SENEAVLEEVRSAVKELTDAFLLYED"
     gene            9109..10083
                     /locus_tag="VVR63_001447"
     CDS             9109..10083
                     /locus_tag="VVR63_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HEU6129456.1"
                     /translation="MDIYIKKAIIHQFSPDDTELFLADKFLNITPKIEEYLRKKIEHV
                     YSDEAKTGIFEEENPFFNHITDDLLETSVTLANLWKEEFSISENLKTNDLIFVQFSKE
                     GVEHFAFLRIALRETLTHLGGEVDNPIKLTQNNLPGFGTGADEALVVNLQSSKYHLIE
                     KRIKYNGTFLNYFSDNLLAVAPKISPKKSIKELEKTAQRIAESFNTDDFQFQSKVKSA
                     IFNNLEESNELSPEKLANDLFDNNLTARLSFIDQVKEAVPEPVQFDEIDVSRQLKKFE
                     NQKLSLSNGIELIVPNNVYQDAESVEFIQNENGTYSILIKNIEDIQSK"
     gene            10083..10697
                     /gene="pmp23"
                     /locus_tag="VVR63_001448"
     CDS             10083..10697
                     /gene="pmp23"
                     /locus_tag="VVR63_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase Pmp23"
                     /protein_id="HEU6129457.1"
                     /translation="MFKRIRRVLVLAVFLFAGYKAYRVHQDVKQVMTYQPMVREILSE
                     KDTPANEELVLAMIYTETKGKEGDVMQSSESASGSTNTINDNASSIRQGIQTLTGNLY
                     LAQKKGVDIWTAVQAYNFGPAYIDFIAQNGKENTLALAKQYSRETVAPLLGNTTGKTY
                     SYIHPISIFHGAELYVNGGNYYYSRQVQLNLYIIKCFTLFSTSG"
     gene            10771..11745
                     /locus_tag="VVR63_001449"
     CDS             10771..11745
                     /locus_tag="VVR63_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HEU6129458.1"
                     /translation="MRKKLFLTSAAVLWAVTAMNSVHAATDVQKVIDETYVQPEYVLG
                     SSLSEDQKNQTLKKLGYNASTDTKELKTMTPDVYSKIMNVANDSSLQLYSSAKIQKLG
                     DKSPLEVKIETPENITKVTQDMYRNAAVTLGMEHAKITVAAPIPVTGESALAGIYYSL
                     EANGAKVPQANKDLAQEELKALSDINAENKDKSGYDANKLNVALADIKSGLAKAKESK
                     GNLTEEDVRKIVEDTLKNYKLDQVITGNQINIIINFALNLSKSDILSNADFTKTLNDL
                     KQSIVSQAGDSFKNINLNFDADKALEDGGNFLSSLWQALVNFFKSFGS"
     gene            11819..13450
                     /gene="rlmD"
                     /locus_tag="VVR63_001450"
     CDS             11819..13450
                     /gene="rlmD"
                     /locus_tag="VVR63_001450"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000914584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEU6129459.1"
                     /translation="MLKKNDIVEVEIVDLTHEGAGVAKVDGLVFFVENALPSEKILMR
                     VLKVNKKIGFGKVEKYLVQSPHRNQDLDLAYLRSGIADLGHLSYPEQLKFKTKQVKDS
                     LYKIAGIADVEVAETLDMEHPVKYRNKAQVPVRRVNGVLETGFFRKNSHNLMPLEDFF
                     IQDPVIDQVVVALRDLLRRFDLKPYDEKEQSGLIRNLVVRRGHYSGQIMVVLVTTRPK
                     VFRVDQLIEQVIKQFPEIVSVMQNINDQNTNAIFGKEWRTLYGQDYITDQMLGNDFQI
                     AGPAFYQVNTEMAEKLYQTAIDFAELKKDDVIIDAYSGIGTIGLSVAKHVKEVYGVEL
                     IPEAVENSQKNASLNKITNAHYVCDTAENAMKKWLKEGIQPTVILVDPPRKGLTESFI
                     KASAQTGADRIAYISCNVATMARDIKLYQELGYELKKVQPVDLFPQTHHVETVALLSK
                     LDVDKHISVEIELDEMDLTSAESKATYAQIKEYVWNKFELKVSTLYIAQIKKKCGIEL
                     REHYNKSKKDKQIIPQCTPEKEEAIMDALRHFKMI"
     gene            13664..13942
                     /locus_tag="VVR63_001451"
     CDS             13664..13942
                     /locus_tag="VVR63_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6129460.1"
                     /translation="MKKDKEVYDKVCEYLSPHLNKDMEVLELACWFRVITVIEANSYV
                     NIRSSRLLPKFKTQKINSWCAAYNIHFNNGYCKQHTNEFKDSLKSLIL"
     gene            14188..14406
                     /locus_tag="VVR63_001452"
     CDS             14188..14406
                     /locus_tag="VVR63_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001207345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU6129461.1"
                     /translation="MALNYKPLWIQLAKKGLKKTDVIAMAGLTTNVMAQMGKDKPITF
                     KNLERICKALSCTPNDIISFEDNFSDEE"
     gene            14799..15824
                     /locus_tag="VVR63_001453"
     CDS             14799..15824
                     /locus_tag="VVR63_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-siderophore ABC transporter
                     substrate-binding protein"
                     /protein_id="HEU6129462.1"
                     /translation="MKNKFFLIAILAMCIVFSACSSNSVKNEENTSKEHAPDKIVLDH
                     AFGQTILDKKPERVATIAWGNHDVALALGIVPVGFSKANYGVSADKGVLPWTEEKIKE
                     LNGKANLFDDLDGLNFEAISNSKPDVILAGYSGITKEDYDTLSKIAPVAAYKSKPWQT
                     LWRDMIKIDSKALGMEKEGDELIKNTEARISKELEKHPEIKGKIKGKKVLFTMINAAD
                     TSKFWIYTSKDPRANYLTDLGLVFPESLKEFESEDSFAKEISAEEANKINDADVIITY
                     GDDKTLEALQKDPLLGKINAIKNGAVAVIPDNTPLAASCTPTPLSINYTIEEYLNLLG
                     NACKNAK"
     gene            15814..16821
                     /locus_tag="VVR63_001454"
     CDS             15814..16821
                     /locus_tag="VVR63_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEU6129463.1"
                     /translation="MRNKKQINLGIIFVICLGLLITIFLSLKLGTKEINIRDFLAAFG
                     MGNTNDDFIKSIIYKRIPRTIFAILAGSSLAISGVLMQSVTRNPIADPGILGINTGAS
                     LSVVIGLSFLGISSSISHISFAIIGGLVSAIFVYAIAVSGKAGLTPIKLALSGTCVSM
                     ALSSFVSFLILPNNNVLDKFRFWQIGSLGAATLSSISTLLPFIILGHLIAIFISSDLN
                     ALAMGDEMAVGLGVNVNRIRSLAIIASVLLCSSITAIGGPIGFVGLIVPHFCGLFISK
                     DIRTMTISSSFIGAELLLICDIIGRMLGKPGEIEVGIITAIIGGPVLIYVTMKNRGVN
                     N"
     gene            16821..>17657
                     /locus_tag="VVR63_001455"
     CDS             16821..>17657
                     /locus_tag="VVR63_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEU6129464.1"
                     /translation="MQNLIIGIQKRKNRITLFSSLFLLIIISLSFFILLIGDESYSFS
                     TLIKVLNSETVPGASFSIMEIRLPKLLAGIIAGWSFGLAGFIFQTMLRNPLASPDIIG
                     VTSSSSIAAVFCILVLKTNSLTTGIISITCGLTSSLILFLLAKKDGFSAARLIILGIG
                     FQAVTRAGTSFLLLKVARYELQEVMRWLSGSLSFTKLDDIPLVLIVSIIATILVLFFN
                     KRLEIIELGEEIAIGLGANPELSRLVLIFCAVSLTAFSTSITGPIACISFLAGPIALN
                     IGK"
BASE COUNT         5604 a         3199 c         3658 g         5196 t
ORIGIN      
        1 gcaacgctga cgaagtttga agagattttc gaagagtata aagagttttg gctgttgaca
       61 aaaatgactc tatctagtag aatagtagat gcgatgagtc gataggtagt cttcgggcta
      121 ctattgagca taaggaggtc ataacgcagg agcggacctt gatgagttgt gtgaacctgc
      181 tcatcacatg aagatgcctc ttaatcccta gtctagcgat tggggatttt tattttccaa
      241 aaaatgatga aaaagctttg caattcatgg aaaaagtagt ataatacttc tattatagaa
      301 atttttagaa aattccgaaa gaggttattt atgggatata cagttgctgt agtcggcgcg
      361 acaggtgctg tcggtgctca gatgataaaa atgttggaag aatcaacact tccaatcgat
      421 aaaatccgtt accttgcttc tgcacgttca gcaggtaagt cattgaaatt taaagatcaa
      481 gatattacga ttgaagaaac gactgaaaca gcttttgaag gagttgatat tgctctcttt
      541 tcagcaggtg gttcgacatc agctaagtat gcaccatacg cagtaaaagc tggcgtggta
      601 gtagtggata atacatctta tttccgtcaa aatccagatg ttcctttggt tgttccagag
      661 gtcaatgctc atgcacttga tgcccacaac ggaatcattg cctgccctaa ctgttcaaca
      721 atccaaatga tggtggctct tgagccggtt cgccaaaaat ggggcttgga ccgtatcatt
      781 gtttcaactt atcaagccgt ttcaggtgct ggtatgggag caattcttga gacacaacgt
      841 gaacttcgtg aggtcttgaa tgatggagtg aaaccacgtg atttgcatgc ggaaatcttg
      901 ccttcaggtg gtgacaagaa acattatcct atcgccttta acgctcttcc acaaattgat
      961 gtcttcactg ataatgatta cacgtacgaa gagatgaaga tgaccaagga aactaagaaa
     1021 attatggaag atgatagcat tgcagtatct gcgacatgtg tgcgtattcc agtcttgtca
     1081 gctcactctg agtcagttta tattgaaaca aaggaagtgg ctccaattga agaagtcaaa
     1141 gcagctatcg catccttccc aggtgctgtt cttgaagatg atgtagttca tcaaatctat
     1201 cctcaagcca tcaatgcagt tggttcacgt gatacctttg ttggtcgtat ccgtaaagac
     1261 ttggatgcag aaaaaggaat tcacatgtgg gttgtttcag ataaccttct caaaggtgct
     1321 gcttggaact cagttcagat tgctgaaact cttcatgaac gtggattggt tcgtccaaca
     1381 gctgaattga aatttgaatt aaaatagtca tatcgtttag gagttcagat gaactccttc
     1441 tttgaaatag agaggtgttt tcgtgtctta tcaagattta aaagaatgta aaatcattac
     1501 agcctttatt acccccttcc atgaggatgg ttccattaac tttgatgcta ttccagcctt
     1561 gattgagcat ttattggccc atcatacgga tggaattctt ctcgcaggaa cgactgctga
     1621 gagtccaact ttgacccacg atgaggagtt ggagttgttt gcggctgtac aaaaggttgt
     1681 caatggacgc gttcctttga ttgcgggtgt aggtactaat gatacgcgtg actctattga
     1741 gtttgtcaaa gaagtagcgg aatttggtgg tttcgcagct gggcttgcta ttgttcctta
     1801 ctacaacaaa ccttctcaag aagggatgta tcagcacttt aaggctattg cagatgcttc
     1861 tgacctacca attattatct ataacattcc agggcgtgta gttgtcgaat tgactccaga
     1921 aaccatgctt cgcttggctg accatccaaa tattatcggt gtcaaagaat gtactagctt
     1981 ggctaatatg gcttacttga ttgagcacaa gcctgaagag ttcttgattt atacaggtga
     2041 ggatggagat gctttccatg ccatgaacct tggggcggat ggggttattt ctgttgcctc
     2101 tcatacaaat ggggatgaaa tgcacgagat gtttactgcc attgcagaaa gcgatatgaa
     2161 gaaagccgca gcaattcagc gtaaattcat tcctaaggtt aatgctctct tctcttatcc
     2221 aagtcctgct ccagttaagg caattcttaa ctatatggga tttgaagctg gacccactcg
     2281 tctacctctt gttccagcac cagaagaaga tgccaaacgc attatcaagg ttgtcgtaga
     2341 tggcgactac gaagcaacta aggcaactgt aacaggggtc ttaagaccag attactaata
     2401 aagacaataa aatccatgac cgaatgaagg atcatggatt tttcttattt tcctaaacag
     2461 aattggctaa agagttgggt gatgagttca tctggagcag catccccagt gatttctccg
     2521 aggatttccc aagtacgagt caagtcaact tgaagcaaat caactggcat ccccagctca
     2581 agaccttgat taacggcttg taggctttca actgcttttt caatcaggga aatgtgacgg
     2641 gcgtttgaca agtaagtagc atcttgctcg accaagccag cattttcaaa gaagaggttg
     2701 ttgattcgct cttcaatctt gtcgatgttt tggtttttaa ggactgaaat acggataacg
     2761 tcttcaggta gtttcgaagt ttcaatcgtt tctggcaggt cggttttatt aagtagaata
     2821 atgcgattgg tatcttggct aatttcaaga agttgtctgt cttgcgcagt cagttgttca
     2881 ctggcattta gcactagtag aaccaagtcg gcttccttga gggctttttt cgaacgctca
     2941 acaccgattt gttccactat gtcatctgtt tcacgaatac cggctgtatc aatcaatttg
     3001 agaggtacac cattgatgtt gacgtactct tcgatgacat ctcgtgttgt cccagcgata
     3061 tctgttacga tagccttgtc ctcacgcaag aggttgttga gaaggctgga tttcccaacg
     3121 ttgggacgtc cgatgatagc tgttgaaatt ccttcacgaa ggattttgcc gcgacgggct
     3181 gttctaagaa gattggttag caattgctca aactccatag tcttctcacg gacaacggca
     3241 gtagtagctt cctcaacatc atcatattca ggatagtcga tattgacctc aacttgggca
     3301 agtgtattga ggatttcttg acgggtattg ttaatgaggt cagaaaggga gccgtctaat
     3361 tgtttgaccg caatgttcat ggccttgtca gtcttggcac ggatgatatc catcacagcc
     3421 tctgcctgtg tcaagtctac gcgaccgttt aaaaaagcac gtttggtaaa ttcaccaggt
     3481 tctgccaacc gagccccttc acgaatagct agctggagaa tttcattggt caccgcaatc
     3541 ccaccgtggg tgttaatctc gataatatcc tcacgagtga aggtctttgg agacttcata
     3601 gccccaacca taacctcgtc catgacttta ccagtcagag gatcaataat gtgaccgtag
     3661 ttgagagtgt ggctggcaac cttgttcaag tcttttcctt taaaaatctt ttgcacaata
     3721 gcaaaactgt ctgttccgct caggcggaca ataccaatag ccccttcacc tagtggagta
     3781 gagatagcag cgatggtatc aaattcacgt gtaatcataa tgtttccttt aattaattgc
     3841 tcttttcttg gaattttcca agtctctttt caaattgtaa caaatttaga ctatttcttc
     3901 aatgggtgct acttggagat tgaaaaagcc taagcaattc tgcttaagct agcttatttg
     3961 gtgcgcattt ccccttgtgg gaaataagtt ccttctggca tgtcgttgat gatgacatga
     4021 acagcagatt gaggtgctcc agtgttgcga acaaccgctt ccgttacttc cttagcaaga
     4081 gctttctttt gctcgagcgt gcgtccttca aataaatcga tgcgtacaaa tggcataata
     4141 gcttcctcca ctagttttga tttcttccat tttaccacat tttgccgttt aaagcttaag
     4201 aaaattatga tatactagaa tgtagcaaaa atttagaaat ggacgtgaag caagaaacat
     4261 ggcacagttg tactatcgtt atgggaccat gaactctggt aaaacgattg agattctcaa
     4321 agtggcctat aactacgagg agcaaggaaa aggtgttgtg attatgacct cggctctgga
     4381 tacgcgtgac ggtgttggct atgtgtcgag tcgaattggc atgaaacgcc ctgcccttgc
     4441 gattgaggaa acaacggata tctttggcta tatccgagac ctaccagaaa aaccttactg
     4501 tgttttggtc gatgaagccc agtttctcaa acgccaccat gtttatgacc tagctcgtgt
     4561 tgtggacgag ttagacatac ccgtcatggc ttttggcttg aaaaatgact ttcgcaatga
     4621 attgttcgaa ggttccaaat atctcttgct tttagcagac aagattgacg aaatcaagac
     4681 catctgtcag tattgcaaga aaaaggcgac catggtgttg cgaacacagg atggactgcc
     4741 cgtttacgat ggagaacaga tccagattgg tggtaatgaa acctatatct cggtttgccg
     4801 taaacattat tttgcccctg aaatcaataa ggagaatgaa gaaaaatgaa catctatgat
     4861 caactacaag ctgtagaaga ccgttatgaa gaactaggag aattgctgag tgaccctgat
     4921 gtcgtttcag acaccaagcg ttttatggag ctttcaaaag aagaagcttc caatcgtgac
     4981 accgtaatag cctaccgtga gtataaacaa gtccttcaaa atatcgtcga tgccgaagag
     5041 atgattaagg aatcaggcgg agatgcggac ttggaagaaa tggccaagca agaactcaaa
     5101 gatgccaagg ctgaaaaaga agaatatgaa gaaaaactga aaattttgct ccttccaaag
     5161 gatccaaacg atgacaagaa tatcatcctt gaaatccgtg gagcagctgg tggagacgaa
     5221 gcggcacttt tcgctggaga tttgctaact atgtaccaaa agtatgcgga agcccaaggt
     5281 tggcgctttg aagtcatgga agcctctatg aatggtgtcg gtggttttaa agaagtggtt
     5341 gctatggttt caggtcagtc tgtatactct aagcttaagt atgaatcagg tgcccaccgt
     5401 gtgcaacgtg ttcctgtgac agaaagccaa ggccgtgttc atacttcgac agcgacagtt
     5461 cttgttatgc cagaagttga agaggttgaa tacgacattg atccaaaaga ccttcgtgtc
     5521 gacatctatc acgcctctgg tgctggtgga cagaacgtca ataaggttgc gactgccgtt
     5581 cgtatcgttc acttgccaac caatatcaag gttgagatgc aggaagaacg tacccagcag
     5641 aagaaccgcg agaaggctat gaagattatc cgtgcacgcg tcgctgacca ctttgctcag
     5701 attgctcagg atgaacaaga cgctgagcgt aagtcgacaa tcggtactgg tgaccgttca
     5761 gaacggatcc gaacttataa cttcccacaa aaccgtgtca cagaccaccg tatcggcttg
     5821 accctccaaa aactagatac gattttgtct ggtaaattgg acgaagttgt ggatgccttg
     5881 gtgctttatg accaaacaca aaaactagaa gaattaaaca aataatgaaa ttagctcaat
     5941 tattttcaaa ttttgaagaa gagttgataa gacaaggaga ggaagcggaa agcctctctt
     6001 ttgtctatcg tagtctgaaa aatctatctt ttacagactt tatttttgcc ctccagcagg
     6061 aggtgacaac agaggaagaa aaacaatttg tagaagatat ttaccagcaa ctagcagctc
     6121 acaagccagc tcagtacatc attggacagg cagattttta tggaatgcat ttaaaggtgg
     6181 atgaacgggt tttgattcct cgtccagaaa cagaggagtt agtggagctt attctaactg
     6241 aaaatcttga gacgaatctc tcagttctgg atattggaac aggtagtgga gctattgctc
     6301 tcgctctagc aaaaaataga ccagattggt cagtgacagc agcagatgtt tctcaagagg
     6361 ccttagagct tgcatcagag aatgctagcg atcaaaatct taatatattt tttaaaaaat
     6421 ctgattgttt tgcagaaatt tctgaaaaat atgatataat tgtatccaat ccaccctata
     6481 tctctcgtga agatgagtca gaggtaggtt tgaatgtttt gcattcggag cctcatctag
     6541 ctctctttgc agacgaggat ggcctagcta tttactgtag aattgcggaa gatgcaaaag
     6601 actatctcaa ggatggtggt aagatttacc ttgaaattgg atacaagcaa ggtcaaagtg
     6661 ttcccgaact ttttagaaaa catcttcctg aaaaaaaagt tcgaacactc aaagaccaat
     6721 ttggtcaaaa taggatggtt gtggttgatg atggacagga ttagacaaga gttggaaaat
     6781 ggtggagctg tcgttctacc tacagagact gtttatggtc tttttgccaa ggccttagat
     6841 gaaaaagcag ttgaccatgt ttaccaactc aaacgtcgtc ctagagataa ggcactcaat
     6901 ctcaatatcg cctctttcga ggatatcttg cacttttcta agaatcagcc aacttatcta
     6961 caaaaacttg tagagacctt tttgccaggt cccttgacca ttattctcga agccaatgac
     7021 cgagttccct attgggtaaa ttctgacctt gcaactattg gatttcggat gcccagtcac
     7081 cctatcacac tggatttaat tcgagagaca ggtcccttga ttgggccgtc tgccaatatc
     7141 tcaggtcagg caagtggtgt aacctttgaa caaattctga aggattttga ccaagaggtt
     7201 ctgggtctgg aagacgatgc ttttctaact ggacaggatt caactattgt ggatttgtct
     7261 ggagacaagg tgaaaatctt acgccaaggc gcaattaaac gagaagatat tcttgctcgg
     7321 ttgccagaga tttcttttga ggaggcttga aatgctaaga gatttgcaag aaacagatgt
     7381 gaaagcgata tgtgacatca accaagaggc tttgggttat acttttagtc cagaggaaac
     7441 ggctagccaa ctagctagac tgtctcagga ttcccatcat ttcctacttg gctatgagga
     7501 tgcagctaat catgtcttac ttggatatgt ccacgctgaa gtttacgaat cactctattc
     7561 caaagcagga tttaatatct tagctttagc agtttcacct caagcgcaag gtcaaggtat
     7621 tggtaaaagt ttactacaag ggttggaaga agaagcaaaa agatgtggtt atgggtttat
     7681 ccgcttaaat tctgccaatc atcgtctggg tgctcatgca ttttatgaaa aagttggcta
     7741 tacttgtgat aaaatgcaga aacggtttat tcgcatcttt tagtttgatt ttcttattgt
     7801 aaaatcaaac taatggacta gtcacacaat aaaggagaag acctatgatt tttgacaaag
     7861 atgattttaa agcatatgat gctgatctct ggaatgctat tgccaaagaa gaagaacgcc
     7921 aacaaaataa tatcgagtta attgcttcgg aaaacgtagt ttccaaggct gttatggcag
     7981 ctcaagggtc tatcttgaca aataaatatg ccgagggtta cccaggacgc cgttattatg
     8041 gtggaactga tgtagtagac gttgtagaga ctcttgctat tgaacgcgca aaagaaattt
     8101 tcggtgctaa atttgccaat gtccaaccac attcaggaag ccaagctaac tgtgcggctt
     8161 acatgtcctt gattgagcca ggtgatacgg ttatgggaat ggatttggca tcaggtggtc
     8221 atttgactca tggggctcct gttagcttct ctggtcaaac ctacaacttt gtttcttata
     8281 gtgttgatcc tgaaacggaa ctcttagact ttgatgctat cttgaaacaa gcccaagaag
     8341 taaaaccaaa actgattgta gctggtgctt cagcatattc tcaaattatc gatttttcaa
     8401 aattccgtga aatcgcagat gctgtcggtg cgaagctcat ggtggacatg gcccatatcg
     8461 ctggtttggt tgcggctggc cttcatccaa gcccagttcc atacgctcat atcacaacaa
     8521 caacgaccca caaaaccctt cgtggacctc gtggtggttt gattttgacc aatgacgaag
     8581 aacttgctaa aaaaatcaat tcagctattt tcccaggtat tcagggcggt cctttagagc
     8641 atgttgtggc ggctaaggca gtttccttca aagaagtttt ggatccagcc ttcaaggaat
     8701 atgctgccaa tgtaattaag aacagcaagg ctatggcaga tgtcttcttg caagaccctg
     8761 atttccgtat tatttcaggt ggaactgaaa accatctctt ccttgttgat gtgactaaag
     8821 ttgtagaaaa cggcaaagtt gctcaaaact tgttggatga agtcaatatt accttaaata
     8881 aaaactcaat cccttacgaa agcttgtcac cattcaagac aagtgggatt cgtatcggag
     8941 cagcagccat tactgcacgt ggatttggtg aagaagaaag tcgcaaagtg gctgaactca
     9001 tcattaaaac ccttaagaat tcagaaaatg aggctgtatt agaagaagtg agaagtgcag
     9061 tcaaagaatt gacagatgcc ttcctactat acgaggacta aaacttttat ggacatttat
     9121 attaagaaag ccattattca ccagttcagt ccggatgata ccgaactgtt cttagcagat
     9181 aagtttctca atattactcc aaaaatcgaa gaatacctgc gtaaaaaaat tgaacatgtg
     9241 tattcagatg aagccaagac tgggattttc gaagaagaaa atcccttctt caatcatatt
     9301 acagacgatt tgttggagac atcagtaacg ctggctaatc tctggaaaga ggagtttagc
     9361 atttctgaaa atctcaagac caatgacttg atttttgttc aattttctaa agaaggtgta
     9421 gaacatttcg ctttcttgcg aattgccctg cgggagacct tgacccacct cggaggagaa
     9481 gttgataatc caatcaagct aactcagaat aacctgcctg gatttggaac aggagctgat
     9541 gaggccttgg tggtcaatct tcagagtagc aagtatcacc tgattgaaaa acgaatcaag
     9601 tacaacggga cttttttgaa ctatttttca gataatcttc ttgctgtcgc tcctaagatt
     9661 tctcctaaaa aatctatcaa ggaactggaa aaaacagccc agagaattgc tgaatctttt
     9721 aacacagatg attttcaatt tcaatccaag gtcaaatcag ctattttcaa caacctagaa
     9781 gaaagcaatg aattgtcacc tgagaaattg gctaatgacc tttttgacaa caatctgacg
     9841 gctcgtttga gctttattga ccaagtcaaa gaagccgtac cagaacctgt tcaatttgat
     9901 gaaattgatg tcagtcgcca attaaagaaa tttgaaaacc aaaaactctc cttatcaaat
     9961 ggaattgagc tcatcgttcc caataacgtc tatcaagacg ccgagtctgt tgagtttatc
    10021 caaaacgaaa atggaaccta ctctatctta atcaaaaata tcgaggatat ccaaagtaaa
    10081 taatgtttaa acgaattcga agagtgcttg tactagcagt cttccttttt gctggctata
    10141 aagcttaccg cgttcatcaa gatgtcaaac aagtcatgac ctatcaaccc atggtgcgag
    10201 aaatattgag tgaaaaagac accccagcaa acgaagagct tgtgcttgct atgatttata
    10261 ctgaaacaaa aggaaaagaa ggcgatgtta tgcagtctag tgagtctgca agtggttcca
    10321 ccaacaccat caatgataat gcctctagca ttcggcaagg cattcaaact ctgacaggca
    10381 atctctatct ggcgcagaag aagggtgtag atatctggac agctgttcaa gcctataatt
    10441 ttggacctgc ctatatcgat tttatcgccc aaaatggcaa ggaaaatacc ttggctctag
    10501 ccaaacagta ctctcgtgag actgttgccc ccttgcttgg taatacgact ggaaagactt
    10561 atagttatat tcatcccatt tccatttttc acggtgccga actctatgta aatggaggaa
    10621 actattatta ttctagacag gtgcaactca acctttacat catcaaatgt ttcactctct
    10681 tttcaacatc tggctagttc aggtgttttt gttataagtt ttctttaaga tagatatatt
    10741 actctagaaa ggtaaaggag gaaattccct atgagaaaga aactctttct gactagtgct
    10801 gcggtcttgt gggcagtaac agctatgaat agcgtccatg cagcaacaga tgttcaaaaa
    10861 gttatcgatg aaacctatgt ccaacctgaa tatgtcctag gttcctccct atctgaagac
    10921 caaaaaaatc aaactcttaa aaaactgggc tacaatgcct caacagatac caaagaactc
    10981 aagaccatga cacctgatgt ttattctaaa atcatgaatg tggccaatga ctctagctta
    11041 cagttgtatt catcagccaa gattcaaaag ctaggtgaca aatcgccact tgaggtcaag
    11101 attgaaacac cagaaaatat cactaaggtg actcaggata tgtaccgaaa cgcagcagta
    11161 acgctgggta tggaacatgc caaaatcact gtagcagccc ctattccagt tacaggtgag
    11221 agtgctttgg ctgggatcta ctattcgcta gaagctaatg gagccaaggt gccgcaagcc
    11281 aataaagatt tggctcaaga agagctaaag gctttgtcag atatcaatgc tgaaaacaag
    11341 gacaaatcag gctatgatgc taataaatta aacgttgccc tagctgatat caagtcagga
    11401 ctcgccaaag ctaaagaaag caagggaaat ctgacagaag aagatgtacg caagattgtt
    11461 gaagatacct taaaaaatta caaacttgat caggtcataa caggaaacca gatcaatatc
    11521 atcatcaatt ttgccttgaa tctctcaaag agtgatatcc tcagcaatgc agatttcact
    11581 aaaaccctaa atgaccttaa acaaagcatc gtatcacaag ctggcgacag ttttaaaaat
    11641 atcaacctta actttgatgc ggataaggcg ctagaggacg gtggtaactt cttaagctcc
    11701 ctctggcaag cccttgtcaa cttcttcaag agttttggtt cttaagaaat ttcatggtat
    11761 aatggatggt aaccgtaacg ttgccgtctt ttttgtcggc caatagaaag agaaaagaat
    11821 gttaaagaaa aatgatattg tagaagttga aattgttgat ttgacccatg aaggggcagg
    11881 agttgccaag gtagatggtt tggtcttttt tgtagagaat gctttaccga gtgaaaaaat
    11941 tctcatgcgt gtcctcaagg tcaataaaaa gattggcttt ggaaaagttg aaaaatacct
    12001 tgtccagtca ccacaccgta atcaagatct agatttggct tacctgcgtt caggaatcgc
    12061 ggatttagga cacctttctt atccagaaca gctcaagttt aaaaccaagc aagtcaagga
    12121 cagtctctac aagattgctg gaattgcaga tgtagaagtt gctgaaacgc ttgatatgga
    12181 acatccagtc aagtatcgca ataaggcgca ggtgcccgtt cgtcgagtga atggtgtctt
    12241 ggaaacagga tttttccgta agaattcgca taacctcatg ccccttgaag atttctttat
    12301 ccaggatcct gtcattgacc aagtcgtagt agctcttcga gacctgctcc gtcgttttga
    12361 tttaaaacct tatgacgaaa aggaacaatc tggattgatt cggaatcttg tggtgcgtcg
    12421 tggtcactat tcaggacaaa tcatggtcgt tttggtgaca actcgtccaa aagtttttcg
    12481 tgttgaccaa ttgattgaac aagttatcaa gcagttccca gagattgtgt ctgtcatgca
    12541 aaatatcaac gaccagaata ccaatgcgat ttttggtaag gagtggcgca ctctttatgg
    12601 tcaagactat attacggacc agatgttggg aaatgacttc caaatcgctg gcccagcctt
    12661 ttaccaagtc aatactgaaa tggcggagaa actctatcaa acagccattg actttgcaga
    12721 gttaaaaaaa gatgatgtga ttattgatgc ctattctggt attggaacca ttggtttatc
    12781 agtcgccaag catgtcaaag aagtctacgg tgttgaactg attccagaag cagtagagaa
    12841 tagccagaag aatgcttctt tgaacaagat tactaatgcc cactatgtct gtgacacggc
    12901 tgaaaatgcc atgaagaaat ggctcaagga aggtattcaa ccaaccgtta tcttggttga
    12961 tcctccacgc aagggcttga cagaaagctt tatcaaagca agcgcccaaa caggagccga
    13021 tcgcatcgcc tatatctcct gcaatgtcgc aaccatggcg cgtgatatta aactatacca
    13081 agagttggga tatgaattga agaaagtcca gccggtggat ctatttcctc aaacgcatca
    13141 cgtcgagacg gtagcacttt tgtccaaact cgatgtcgat aagcacataa gtgttgaaat
    13201 tgagctggat gagatggatt tgacaagtgc ggagagcaaa gcaacatatg ctcaaatcaa
    13261 agaatatgtt tggaataaat ttgaattaaa agtttcgaca ttatatattg cacagataaa
    13321 aaagaaatgt ggaatagaat tacgagaaca ttacaacaag tctaaaaagg ataaacaaat
    13381 tattccacag tgtacacctg aaaaagaaga agccatcatg gatgctttga gacacttcaa
    13441 aatgatttaa tagaaaagaa tgacagtata tgactttctg catttattac attcctactt
    13501 ggtataggaa cagctattat tcctttcttg caaggtatca attagaaaat aggctcaata
    13561 taaagattga taggatcatt tttatattta aaggagcgtt gaaatgattg ataaaggcaa
    13621 caaaaaattt taggataaat ttgctaagtt gtatgcccct tttatgaaaa aagataaaga
    13681 ggtttatgat aaagtttgtg aatatcttag tcctcatttg aataaagata tggaggtgct
    13741 tgaacttgct tgttggtttc gtgtcataac agttatagag gcaaatagtt atgtaaatat
    13801 aaggagttca agacttctac caaagtttaa aactcaaaaa ataaatagtt ggtgtgctgc
    13861 ttacaatatc cattttaata atggatattg taagcagcat accaatgaat ttaaagattc
    13921 tttaaagagt cttattttgt gatgaaaatt taatatgtaa atctcagacg atagaaatta
    13981 aaaactctat cgtctttttt atactcaaaa ttaggaggta aaaatggtaa ggataagagg
    14041 tcccacttaa aacaatttat ggcaaaataa ggacggaata acacaacaaa ttctctaaaa
    14101 caaatcacta aatcaatgta agattgaatg aaatcaatat ttatgctata attaaataaa
    14161 tctaatgaag aaaaaaagag ggatattatg gcacttaact ataaaccatt atggatacag
    14221 ttagcaaaaa aaggactaaa gaaaacagat gtaatagcta tggcaggact tacaacaaat
    14281 gttatggcac aaatgggaaa ggataaacca attacattta agaatttaga aagaatatgt
    14341 aaggctttat cttgcactcc taatgatatt attagttttg aagataattt tagtgacgag
    14401 gaatagaaaa tgactttaag gacagaagat caagttaggg attatgcaag agaagtatag
    14461 gctttaatga agttgaagaa aacatcaatc aaggtactgg tcaaataact acttttaatc
    14521 aattaggctt caaggggtat tcagataagc cagatggttg gtatttacct aaaaatatga
    14581 atgatgtagc aataatcctt gaaacaaaat cagaagaaag agatattagc aaacaaattt
    14641 ttattgatga gttaatgaaa aatatagaca taatttaact aaaaataaaa actagatcct
    14701 tttttgaaaa aattatatta ttaaatttgt aactgtatct attgacaatg ataattatta
    14761 tcgatacaat agacttgaaa tatgtttaag gagtttttat gaaaaacaaa ttttttctaa
    14821 tagctatttt agctatgtgt atagttttta gcgcttgttc ttctaattct gttaaaaatg
    14881 aagaaaatac ttctaaagag catgcgcctg ataaaatagt tttagatcat gctttcggtc
    14941 aaactatatt agataaaaaa cctgaaagag ttgcaactat tgcttgggga aatcatgatg
    15001 tagcattagc tttaggaata gttcctgttg gattttcaaa agcaaattac ggtgtaagtg
    15061 ctgataaagg agttttacca tggacagaag aaaaaatcaa agaactaaat ggtaaagcta
    15121 acctatttga cgatttggat ggacttaact ttgaagcaat atcaaattct aaaccagatg
    15181 ttatcttagc aggttattct ggtataacta aagaagatta tgacactcta tcaaaaattg
    15241 ctcctgtagc agcatacaaa tctaaacctt ggcaaacttt atggagagat atgattaaaa
    15301 ttgattcaaa agccttaggt atggaaaaag aaggtgatga gttaatcaaa aatactgaag
    15361 ctcgtatatc caaagaatta gaaaaacatc cagaaatcaa aggaaaaatc aaaggaaaaa
    15421 aagtattatt tactatgatt aatgctgcag atacatcaaa attctggatt tatactagca
    15481 aagatccaag agcaaattat ttaacagatt taggtctagt tttccctgaa tcattaaaag
    15541 aatttgagag tgaagatagt tttgcaaagg aaatttctgc agaagaagca aataagataa
    15601 atgatgctga tgtaatcata acttatggtg atgataaaac tcttgaagct ttacaaaaag
    15661 atcctctttt aggtaaaata aatgcaatta aaaatggtgc cgttgctgta attccagata
    15721 atacaccgtt agcagcctca tgcactccaa caccactttc aataaactat actattgaag
    15781 aatacctaaa tcttttagga aatgcatgca aaaatgcgaa ataaaaaaca aataaaccta
    15841 ggcataattt ttgtaatctg cctaggtctt cttattacaa tatttttgtc attaaagctt
    15901 ggaacaaaag aaattaatat cagagatttt ttagcagctt ttggaatggg caatacaaat
    15961 gatgatttta ttaaatcaat tatatataaa agaataccta gaactatttt tgcaatttta
    16021 gcaggttcta gtcttgccat aagcggtgta ttgatgcaat cagttactag aaacccaata
    16081 gctgatccag gtatactcgg tataaacaca ggagcaagtc ttagtgtagt aattggtctt
    16141 tcttttttag gaatttcatc aagcataagc catataagtt ttgcaatcat tggtggctta
    16201 gtaagtgcaa tttttgtata cgcgattgct gtaagcggaa aagcaggcct tacccctata
    16261 aaacttgcct tatcaggaac ttgtgttagt atggctttaa gcagttttgt aagtttttta
    16321 attttaccga ataataacgt cttagacaaa tttagatttt ggcaaatagg tagccttgga
    16381 gcagctacat tatcttctat atctacacta ctacctttta taattttagg tcacttgata
    16441 gctatattta tttcatcaga tttaaacgct ttagctatgg gtgatgaaat ggctgttggt
    16501 cttggagtta atgttaatag gataagatca cttgcaataa ttgcaagtgt gcttttatgt
    16561 tcaagtatta ctgcaattgg tggacctatt ggcttcgtag gtcttatagt tcctcacttt
    16621 tgtggcttat ttataagcaa agatatacgc acaatgacca tttcttcatc ttttataggt
    16681 gcagagctct tgcttatatg tgatataatc ggccgtatgt taggtaaacc aggtgaaatt
    16741 gaagtaggga taattactgc aataatcggg ggtccagtac ttatttatgt aactatgaaa
    16801 aatagagggg ttaataacta atgcaaaatt taattatagg tattcaaaaa agaaaaaata
    16861 gaataacact attttcctca ctatttttat taataataat cagtctatca tttttcattt
    16921 tacttatcgg agatgaaagt tattcttttt caactttgat taaagtctta aatagtgaaa
    16981 ctgttcctgg agctagtttt tcgattatgg aaattagatt accaaaatta ttagcaggaa
    17041 ttatagctgg ctggtctttt ggattggcag gatttatctt tcaaactatg ttaagaaatc
    17101 ctcttgcaag tcctgatata atcggtgtca caagttcttc atctattgca gcggtctttt
    17161 gcatattggt attaaaaaca aatagtttaa ctactggaat tatttcaata acttgtggac
    17221 taacatcatc tttaatatta tttttactag ctaaaaaaga tggtttttca gcagcaagac
    17281 tgataatatt aggtattggt tttcaagctg tcacaagagc aggcacctca tttttattgt
    17341 tgaaagtagc aagatatgaa ttacaagaag ttatgagatg gctcagtggc tctttatctt
    17401 ttacaaagtt agatgacata cctcttgttc taatagtaag tattattgct actatattag
    17461 ttttattttt taataaaaga ctagaaatta ttgaacttgg tgaagaaata gcaatcggac
    17521 ttggagcaaa tcccgagctt tcaaggcttg ttttaatttt ttgcgctgta tctttaactg
    17581 ctttttctac ttcaattaca ggaccaatag cttgtatatc ttttttagct ggtcccatag
    17641 ccttaaatat tggcaag
//
LOCUS       DAVHTH010000039        17479 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.039, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000039 DAVHTH010000000
VERSION     DAVHTH010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17479)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17479)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17479
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.039"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            complement(<1..1229)
                     /locus_tag="VVR63_001456"
     CDS             complement(<1..1229)
                     /locus_tag="VVR63_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 20 glycosylhydrolase"
                     /protein_id="HEU6129465.1"
                     /translation="MVRFTGLSPKQTQAIEVLKGHISLPDVEVAVTQSDQASISIEGE
                     EGHYQLTYRKPHQLYRALSLLVTVLAEADKVEIEEQAAYEDLAYMVDCSRNAVLNVAS
                     AKQMIEVLALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSAEELQEIEAYAQQFDMTF
                     VPCIQTLAHLSAFVKWGVKEVQELRDVEDILLIGEEKVYDLIDGMFATLSKLKTRKVN
                     IGMDEAHLVGLGRYLILNGVVDRSLLMCQHLERVLDIADKYGFHCQMWSDMFFKLMSA
                     DGQYDRDVEIPEETRVYLDRLKDRVTLVYWDYYQDSEEKYNRNFRNHHKISHDLAFAG
                     GAWKWIGFTPHNHFSRLVAIEANKACRANQIKEVIVMGWGDNGGETAQFSILPSLQIW
                     AELSYRNDLDSLSAHFKT"
     gene            complement(1223..2092)
                     /locus_tag="VVR63_001457"
     CDS             complement(1223..2092)
                     /locus_tag="VVR63_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEU6129466.1"
                     /translation="MTIATIDIGGTGIKFASLTPDGKILDKTSISTPENLEDLLAWLD
                     QRLSEQDYSGIAMSVPGAVNQETGVIDGFSAVPYIHGFSWYEALSSYQLPVHLENDAN
                     CVGLSELLAHPELENAACVVIGTGIGGAMIINGRLYRGRHGLGGEFGYMTTLAPAEKL
                     NNWSQLASTGNMVRYVIEKSGHTDWDGRKIYQEAAAGNALCQEAIERMNRNLTQGLLN
                     IQYLIDPDVISLGGSISQNPDFIQGVKKAVEDFVDAYEEYTVAPVIQACTYHADANLY
                     GALVNWLQEEKQW"
     gene            complement(2176..4821)
                     /locus_tag="VVR63_001458"
     CDS             complement(2176..4821)
                     /locus_tag="VVR63_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000432759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HEU6129467.1"
                     /translation="MENVVVHIISHSHWDREWYLPFESHRMQLVELFDNLFDLFENDP
                     EFKSFHLDGQTIVLDDYLQIRPENRDKVQRYIDEGKLKIGPFYILQDDYLISSEANVR
                     NTLIGQQEAAKWGKSTQIGYFPDTFGNMGQAPQILQKSGIHVAAFGRGVKPIGFDNQV
                     LEDEQFTSQFSEMYWQGVDGSRVLGILFANWYSNGNEIPVDKDEALTFWKQKLSDVRA
                     YASTNQWLMMNGCDHQPVQKNLSEAIRVANELFPDVIFVHSSFDEYVQAVEGALPEHL
                     STVTGELTSQETDGWYTLANTSSSRIYLKQAFQENSNLLEQVVEPLTIITGGHNHKDQ
                     LTYAWKTLLQNAPHDSICGCSVDEVHREMETRFAKVNQVGNFVKSNLLNEWKGKIATD
                     KAQSDYLFTVINTGLHDKVDTVSTVIDVATCDFKELHPTEGYKKMAALILPSYRVEDL
                     DGRPVEVTIEDLGANFEYDLPKDKFRQARIARQVRVTIPVHLAPLSWTTFQLLEGEQE
                     HREGIYQNGVIDTPFVTVSVDDNITVYDKTTHEAYEDFIRFEDRGDIGNEYIYFQPKG
                     TEPIFAELKGHEVLENTDRYAKILLKHELTVPVSADEKLEEEQQGIIEFMKREAGRSE
                     ELTNIPLETELIVFVDNPQIRFKTRFTNTAKDHRIRLLVKTHNTRPSNDSESIYEVVT
                     RPNKPAASWENPENPQHQQAFVSLYDDEKGVTVSNKGLNEYEILGDNTIAVTILRASG
                     ELGDWGYFPTPEAQCLREFEVEFAIECHQAQERFSAYRRAKALQTPFTSLQLARQEGS
                     VVATGSLLSHSVLSIPQVCPTAFKVAENEEGYVLRYYNMSQENVRISEHQQTILDLLE
                     RPYPVHSGLLAPQEIRTEFIKKEEI"
     gene            complement(4912..6192)
                     /locus_tag="VVR63_001459"
     CDS             complement(4912..6192)
                     /locus_tag="VVR63_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HEU6129468.1"
                     /translation="MIYPKEIVREWLDEVAERAKDHPEWVDVFERCYTDTLDNTVEIL
                     EDGSTFVLTGDIPAMWLRDSTAQLRPYLHVAKRDALLRQTIAGLVKRQMTLVLKDPYA
                     NSFNIEENWKGHHETDHTDLNGWIWERKYEVDSLCYPLQLAYLLWKETGETSQFDETF
                     VAATKEILHLWTVEQDHKNSPYRFVRDTDRKEDTLVNDGFGPDFAVTGMTWSAFRPSD
                     DCCQYSYLIPSNMFAVVVLGYVQEIFAALNLADSQSVIADAKRLQDEIQEGIENYAYT
                     TNSKGEKIYAFEVDGLGNASIMDDPNVPSLLAAPYLGYCSIDDEVYQATRRTILSSEN
                     PYFYQGEYASGLGSSHTFYRYIWPIALSIQGLTTRDKAEKKFLLDQLVACDGGTGVMH
                     ESFHVDDPTLYSREWFSWANMMFCELVLDYLDIR"
     gene            6363..8447
                     /locus_tag="VVR63_001460"
     CDS             6363..8447
                     /locus_tag="VVR63_001460"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HEU6129469.1"
                     /translation="MKPLLETIDTRFGTASKHAFSWGNTLPYTGVPFGMNYFVPQTSD
                     QDGSWFFDPHLPIFQGIRLTHQPSPWIGDYSWLLLTPVTSQLGGDSLFHRQSSYDIDK
                     ACFQPHYLKLFSLRYQIETQLTPTCYGASIRLNQKQGKALSLYLHAADELTVEQVDKR
                     TLALRQEGKTETNKNSLTMFTALQMNTDILAISQEAGDWRIDLVSSQTEMQLATSFIS
                     PSQALINLPQEDFDSCKSSAQADWENLLHRFDIIETGEADRTFFDHCLYRLFLFPQTF
                     YEVDESGQAIHMDLATGTVKPGVLFSNNGFWDTFRTTFPLFALIIPEHYQRFLEGFLN
                     SYRDTGFLPKWLAPDERGMMPGTLLDGIIADSACKDMAPDLEGELFQAMLETASKADP
                     LGINGRHGLAQYQELGYLSTDHHESVSHTLDYAYSDFCIASCAKKLENIEIAETYKAA
                     SQNYRQLFDAETGYMRARDNQGNFHPDFSPYSWGRDYAECSAIQATLGVLHDIPGLIQ
                     LMGGKETFSNYLLKTCQDAPLFETTGYGYEIHEMSEMATAPFGQIAISNQPSFHIPYL
                     FRYSDYPDYTALLIKTLRQKAFHPSWEAYPGDEDNGSLSAWYIWSALGFYPTCPGKPS
                     YDLGIPLFDHLRVYLAKEDKWLDIHTKQNHNHFNFVKECRLDKTLVSTIQHQDLLKAE
                     QLTFTLSWLPSH"
     gene            complement(8487..10166)
                     /locus_tag="VVR63_001461"
     CDS             complement(8487..10166)
                     /locus_tag="VVR63_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000721501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HEU6129470.1"
                     /translation="MKKIKPHGPLPSQTQLAYLGDELAAFIHFGPNTFYNQEWGTGQE
                     DPERFNPSQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGK
                     GDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPNYG
                     NAGKFAEVWMDGARGEGAQQVNYEFEKWFETIRDLQGDCLIFSTEGTSIRWIGNERGY
                     AGDPLWQKVNPDKLGTEAELDYLQHGDPSGTIFSIGEADVSIRPGWFYHEDQDPKSLE
                     ELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKDIERLYEFATYRNELYKEDLALGAEVS
                     GPALSADFACRHLTDGLETSSWANDADLPIQLELDLGSPKTFDVIELREDLKLGQRIA
                     AFHVQVEVDGVWQEFGRGFTVGHKRLLRGPLVEAQKVRVMITEAQSIPVLTKISLYKT
                     PELSKKEVVQELAFAEKSLAVAKGENAYFTVKRRECSGPLEAKISIQPGTGVHGVAYQ
                     DEIYVLQFQAGESKKDLHLPTLYFAGDKTLDFYLNLTVDGQLVDQLQVQVS"
     gene            10922..12151
                     /gene="arcA"
                     /locus_tag="VVR63_001462"
     CDS             10922..12151
                     /gene="arcA"
                     /locus_tag="VVR63_001462"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HEU6129471.1"
                     /translation="MSSHPIQVFSEIGKLKKVMLHRPGKELENLLPDYLERLLFDDIP
                     FLEDAQKEHDAFAQALRDEGIEVLYLEQLAAESLTSPEIRDQFIEEYLDEANIRDRQT
                     KVAIRELLHGIKDNQELVEKTMAGIQKVELPEIPDEAKDLTDLVESDYPFAIDPMPNL
                     YFTRDPFATIGNAVSLNHMFADTRNRETLYGKYIFKYHPIYGGKVDLVYNREEDTRIE
                     GGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKKNVGFKKVLAFEFANNRKFMHLDT
                     VFTMVDYDKFTIHPEIEGDLHVYSVTYENEKLKIVEEKGDLAELLAQNLGVEKVHLIR
                     CGGGNIVAAAREQWNDGSNTLTIAPGVVVVYDRNTVTNKILEEYGLRLIKIRGSELVR
                     GRGGPRCMSMPFEREEV"
     gene            12209..13225
                     /gene="argF"
                     /locus_tag="VVR63_001463"
     CDS             12209..13225
                     /gene="argF"
                     /locus_tag="VVR63_001463"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HEU6129472.1"
                     /translation="MTNSVFQGRSFLAEKDFTRAELEYLIGLSAHLKDLKKRNIQHHY
                     LAGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVQENFGRLEGLTLV
                     YCGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEKEIVELAEGFAKESGAHVLITED
                     ADEAVKDADVLYTDVWVSMGEEDKFAERVALLKPYQVNMDLVKKAGNENLIFLHCLPA
                     FHDTHTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLY
                     IPKV"
     gene            13390..14337
                     /gene="arcC"
                     /locus_tag="VVR63_001464"
     CDS             13390..14337
                     /gene="arcC"
                     /locus_tag="VVR63_001464"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HEU6129473.1"
                     /translation="MANRKIVVALGGNAILSSDPSAKAQQEALVETAKHLVKLIKNGD
                     DLIITHGNGPQVGNLLLQHLASDSEKNPAFPLDSLVAMTEGSIGFWLKNALQNALLDE
                     GIEKNVASVVTQVVVDKNDPAFVNLSKPIGPFYSEEEAKAEAEKSGATFKEDAGRGWR
                     KVVASPKPVDIKEIETIRTLLNNGQVVVAAGGGGIPVVKENNGHLTGVEAVIDKDFAS
                     QRLAELVDADLFIVLTGVDYVFVNYNKPNQEKLEHVNVAQLEEYIKQDQFAPGSMLPK
                     VEAAIAFVNGRPEGKAVITSLENLGALIESESGTIIEKG"
     gene            14548..16059
                     /locus_tag="VVR63_001465"
     CDS             14548..16059
                     /locus_tag="VVR63_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004191872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HEU6129474.1"
                     /translation="MSEKAKKGFKMPSSYTVLLIIIAIMAVLTWFIPAGAFIEGIYET
                     QPQNPQGIWDVLMAPIRAMLGTHPEEGSLIKETSAAIDVAFFILMVGGFLGIVNKTGA
                     LDVGIASIVKKYKGREKMLILVLMPLFALGGTTYGMGEETMAFYPLLVPVMMAVGFDS
                     LTGVAIILLGSQIGCLASTLNPFATGIASATAGVGTGDGIVLRLIFWVTLTALSTWFV
                     YRYADKIQKDPTKSLVYSTRKEDLKHFNVEESSSVESTLSSKQKSVLFLFVLTFILMV
                     LSFIPWTDLGVTIFDDFNAWLTGLPVIGNIVGSSTSALGTWYFPEGAMLFAFMGILIG
                     VIYGLKEDKIISSFMNGAADLLSVALIVAIARGIQVIMNDGMITDTILNWGKEGLSDL
                     SSQVFIVVTYIFYLPMSFLIPSSSGLASATMGIMAPLGEFVNVRPSLIITAYQSASGV
                     LNLIAPTSGIVMGALALGRINIGTWWKFMGKLVVAIIVVTIALLLLGTFLPFL"
     gene            16081..17412
                     /locus_tag="VVR63_001466"
     CDS             16081..17412
                     /locus_tag="VVR63_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HEU6129475.1"
                     /translation="MKIDITNQVKDEFLISLKTLISYPSVLNEGENGTPFGQAIQDVL
                     EKTLEICQDIGFTTYLDPKGYYGYAEIGQGAELLAILCHLDVVPSGDEADWQTPPFEA
                     TIKDGWVFGRGVQDDKGPSLAALYAVKSLLDQGIQFKKRVRFIFGTDEETLWRCMARY
                     NTIEEQASMGFAPDSSFPLTYAEKGLLQVKLHGPGSDQLELEVGGAFNVVPDKANYQG
                     PLYEQVCNDLKEAGYDYQSTEQTVTVLGVPKHAKDASQGINAVIRLATILAPLQEHPA
                     LSFLATQAGQDGTGRQIFGDIADEPSGHLSFNVAGLMINHERSEIHIDIRTPVLADKE
                     ELVELLRRCAQNYQLRYEEFDYLAPLYVAKDSKLVSTLMQIYQEKTGDNSPAISSGGA
                     TFARTMPNCVAFGALFPGAKQTEHQANECAVLEDLYRAMDIYAEAVYRLAT"
BASE COUNT         4908 a         3995 c         3598 g         4978 t
ORIGIN      
        1 gtcttgaaat gcgcagacaa actatctagg tcattgcgat agctgagttc tgcccagatt
       61 tgcaagcttg gtaggataga gaactgggca gtttcaccac cattgtctcc ccaacccatt
      121 acgatgactt ctttaatctg attggcacgg caggctttat tagcctcgat agccactaga
      181 cggctaaaat ggttgtgagg tgtaaagcca atccacttcc aagctccccc tgcaaatgca
      241 aggtcatggc taatcttgtg atgattgcgg aaattacggt tgtatttttc ctcgctatcc
      301 tgataataat cccagtaaac cagagtcaca cggtctttga gacggtctag gtagacacga
      361 gtttcctctg gaatttccac atcacgatcg tactggccat ccgctgacat gagtttgaag
      421 aacatatcac tccacatctg gcagtggaaa ccatatttgt cagcaatatc cagcacgcgc
      481 tccaagtgtt ggcacatgag gagactacga tccacaacac cgttcaaaat caggtagcgt
      541 cccaaaccaa ccaagtgggc ttcgtccatc ccgatattga ccttgcgagt cttcagttta
      601 gacaacgtgg caaacatgcc atcaatcagg tcataaacct tttcttcgcc aatgagaaga
      661 atgtcctcta catcacggag ctcctgcact tccttgacac cccatttgac aaaggccgac
      721 aagtgggcca aggtctggat gcatggtaca aaggtcatgt caaactgttg agcataggct
      781 tcgatttcct gcaactcctc tgctgaataa gctccacgga aatagccaaa gtaaggctgt
      841 ccttcaatct ggtaagtgtc ttccatgtaa agctcaaagg ttgagtagcc catgagagcc
      901 aagacctcaa tcatctgctt ggcagaagcc acattcagca ccgcatttcg agaacagtca
      961 accatgtaag ccaaatcttc gtaagctgct tgttcctcaa tctctacttt atcagcttct
     1021 gctagaactg ttaccaacaa ggataaggca cgataaagtt ggtgaggttt gcggtaggtc
     1081 aattgatagt gaccttcctc accctcgata gagatagagg cttggtcaga ctgagtgaca
     1141 gccacttcca catctggtag agaaatgtga ccttttaaaa cctcaatagc ttgcgtttgt
     1201 ttgggactaa gtcctgtaaa tcttaccatt gcttttcctc ctgtagccag ttgacaaggg
     1261 caccgtagag attggcatct gcgtgatagg tgcaggcctg gataactggt gcgaccgtgt
     1321 attcttcgta ggcatcgaca aagtcttcaa cagccttctt aacaccttgg ataaaatctg
     1381 gattttgact gatagagcca cccagactga tgacatctgg atcgatcaga tactggatat
     1441 tgagcaagcc ttgcgtcaga ttgcggttca tgcgctcaat ggcttcttga caaagagcat
     1501 taccagctgc ggcctcttgg taaatcttgc gaccgtccca atcagtatga ccagattttt
     1561 caatcacgta tcgtaccata ttcccagttg atgctagttg cgaccagtta ttaagttttt
     1621 cagcaggggc aagggttgtc atgtagccaa attctccacc cagaccgtgg cgacctcgat
     1681 aaagtctacc attgataatc atggctccgc caatccctgt cccaatcacg acacaggctg
     1741 cattttcaag ctctggatga gctagtagtt cactgagtcc aacgcagttg gcatcatttt
     1801 ctaaatggac aggtagctga taagagctaa gcgcctcata ccaagaaaag ccatggatgt
     1861 agggcaccgc actgaagcca tcaatcacac ctgtctcttg attgaccgca cctggaacgc
     1921 tcatagcaat cccactgtaa tcctgttctg acaagcgttg atctagccac gctagtaaat
     1981 cctccaagtt ttcaggcgtt gaaatacttg tcttatccag tattttccca tcaggagtca
     2041 gactggcaaa cttaatccca gtccctccga tatcaatcgt tgcaatggtc attgttttta
     2101 ccataaaaag gggcgaatca gcagttagtt cttacttttt cgcccctcct ttcttttgat
     2161 gtttactttt tgaaattaaa tttcttcttt tttgatgaat tctgtacgaa tctcttgtgg
     2221 agccaatagt cctgaatgaa ctggatatgg tcgctcaagt aagtcaagaa tggtttgttg
     2281 atgttctgat atgcgcacat tttcttgact catattatag taacggagga catagccttc
     2341 ttcattttcc gccactttaa aggctgttgg acaaacttgc ggtatgctga gaacagaatg
     2401 gctcaagagg ctaccagtcg caaccacgct tccttcctgt ctagcaagct gaaggctggt
     2461 aaacggtgtc tgcaaggctt tggcacgacg ataggctgag aagcgttctt gggcttggtg
     2521 gcattcaatc gcaaattcga cttcaaactc acgcaagcat tgtgcttctg gcgttgggaa
     2581 gtagccccag tcacctagct cacctgatgc acgcaaaatg gtcacggcaa tggtgttatc
     2641 cccaaggatt tcgtattcat tcaatccctt gttggataca gtcacccctt tttcatcgtc
     2701 atacagactg acaaaagctt gttggtgttg aggattttca ggattttccc atgaagcagc
     2761 tggtttgttt ggtcgtgtca ccacctcata gatactttca gaatcattgc ttggacgcgt
     2821 gttatgagtc ttgaccaaga gacggatacg gtgatccttg gcagtgttag taaagcgagt
     2881 cttgaagcgg atttgtggat tgtcaacaaa gacaatcaac tcagtttcca gaggaatgtt
     2941 tgtcaattct tctgaccgtc cagcctcacg cttcataaac tcgatgatac cttgttgctc
     3001 ttcttctagc ttttcatccg cactgacagg cacggtcaat tcatgtttga gcaagatttt
     3061 agcatagcga tctgtgtttt ccaagacctc gtggccctta agctctgcaa agattggctc
     3121 tgttcctttt ggttggaaat agatatactc gtttccgatg tcaccccggt cttcgaagcg
     3181 gataaaatct tcataggctt cgtgagttgt cttatcatag actgtgatgt tgtcatccac
     3241 actcaccgtt acgaatggtg tatcaatcac tccgttttgg taaataccct cacggtgttc
     3301 ttgttctcct tccagcaatt ggaaggttgt ccaagaaagc ggtgctaggt gaactggaat
     3361 ggtcacgcgc acttgtcgag caatacgagc ttggcggaac ttatcttttg gtaaatcgta
     3421 ttcaaaatta gctccgaggt cttcgattgt aacctctaca ggacgaccat ccaagtcctc
     3481 cacacggtaa cttggcaaga taagagcagc catctttttg tagccttctg ttgggtgcaa
     3541 ttccttgaaa tcacaagtcg ccacatcaat cactgtgctg acagtatcga ccttatcatg
     3601 caagcctgtg ttaatgacag taaagagata gtcactttga gccttatccg tagcaatttt
     3661 acccttccac tcgttgagca aattactttt aacaaagttt cctacttggt tgaccttggc
     3721 aaaacgcgtt tccatctcgc ggtgaacttc gtccacgcta cagccacaga tactatcatg
     3781 tggcgcattc tgcaaaagtg ttttccaagc ataggtcaac tggtccttgt ggttgtgtcc
     3841 accagtgata atagtcaagg gttctaccac ttgctctagg aggttgctat tttcttggaa
     3901 ggcttgtttt aggtaaatgc gggatgaaga agtgttggca agtgtgtacc agccatctgt
     3961 ttcctgactg gtcaactcgc ctgtaacagt tgataagtgt tcaggaagcg caccttctac
     4021 agcttgaaca tattcatcaa aagaactatg aacaaagatt acatccggga agagttcatt
     4081 tgccacacga atggcttcgc tcagattttt ctgtacaggc tggtggtcac agccgttcat
     4141 catcaaccat tggttggtcg aagcgtaggc acgcacatct gacaattttt gtttccagaa
     4201 ggtcaaggcc tcatctttgt caactgggat ttcattccca ttactgtacc agttggcaaa
     4261 gagaatacct aaaacacgac taccatccac accctgccag tacatttctg aaaactggga
     4321 tgtaaactgc tcatcttcaa ggacttggtt gtcaaatcca atcggcttca caccacgacc
     4381 aaaggccgcc acgtgaatgc ctgatttttg aagaatttga ggcgcttgtc ccatatttcc
     4441 aaaggtatct ggaaagtagc caatctgggt tgatttaccc catttggcag cttcttgttg
     4501 accaatcaag gtattgcgga cattggcttc actggagatc aagtagtcat cctgcaagat
     4561 gtaaaaggga ccaattttaa gtttgccctc gtcaatgtag cgttggacct tgtcgcgatt
     4621 ttcagggcga atttgtaagt agtcatcaag gacaatagtt tgtccatcca agtggaaact
     4681 cttgaactca gggtcatttt caaagagatc aaagagattg tcaaacaatt ccaccaactg
     4741 catacgatgg ctttcaaaag gcaagtacca ctcacggtcc cagtgactat gtgagataat
     4801 atgtacaaca acattttcca tgaagtaaaa cctcattcta aatttaaatt ttaacgtttt
     4861 aaatgtaaac ttgtgattct gataagaatc ggttgagcta aagcgagccc cttagcgaat
     4921 atccaagtaa tccaagacca actcacagaa catcatgtta gcccaggaga accattcacg
     4981 agagtagagg gtcggatcat ctacgtggaa gctttcgtgc atgacacctg taccaccatc
     5041 gcaggcaacc agctgatcca gcaagaattt tttctctgcc ttatctcttg ttgtcaatcc
     5101 ttggatagaa agggcgattg gccagatata gcgatagaag gtatgagaac ttccgagacc
     5161 gctagcgtat tctccttggt agaagtatgg attttcagag ctcagaatgg tacggcgagt
     5221 ggcttgatac acttcatcat cgatcgaaca gtagcccaga tagggcgcag ctagtagact
     5281 tggtacattt ggatcatcca tgatgctggc atttcctagg ccatctactt caaaagcgta
     5341 aatcttttcg cccttgctgt tggtggtgta agcgtagttt tcgattcctt cttggatttc
     5401 atcctgaaga cgcttggcat cagcaataac actctggcta tcagctaggt ttaatgctgc
     5461 gaagatttct tgcacataac ccaagactac tacagcaaac atatttgacg gaatcaagta
     5521 actatactgg caacagtcat cactcggacg aaaggctgac caagtcatac ctgtcactgc
     5581 aaagtcaggt ccaaagccat catttaccaa ggtgtcttcc ttacggtccg tatctcggac
     5641 aaaacgataa ggagagttct tgtggtcttg ttcaactgtc catagatgga gaatttcctt
     5701 agtcgctgcg acaaaagtct catcaaactg actagtctcg ccagtttctt tccagaggag
     5761 ataagccaac tgcaaaggat agcaaagcga gtccacctca tacttgcgtt cccaaatcca
     5821 gccattaagg tcggtgtggt cggtctcgtg gtgccccttc cagttttcct ctatgttgaa
     5881 ggaattggca taaggatcct tgagtaccaa ggtcatctga cgtttgacca aacctgcaat
     5941 ggtctgacgc aggagggcat ctcttttagc tacatgcagg tagggtctga gttgggctgt
     6001 cgaatcccga agccacatag caggaatatc cccagtcaag acaaaagttg aaccatcttc
     6061 taagatttca accgtattgt ccaaggtatc ggtgtagcaa cgctcgaaaa catccaccca
     6121 ctctggatgg tccttagccc gctctgctac ttcatctagc cattctctaa caatttcttt
     6181 cggataaatc atcgtgcaat tccctctttc aaacaagttt catgttcagt atatagcttt
     6241 tgagacagaa aatacataca caaatgatag tcatttttct acaaaatagt tatttttgaa
     6301 actccttttc taaaggccct ctttttctga tataatgtag aaaaacagct aaaggaaaga
     6361 ctatgaaacc actacttgaa accatcgata cccgctttgg tactgctagc aagcatgcct
     6421 tctcttgggg aaataccctg ccatacacag gcgtgccttt tgggatgaat tactttgtgc
     6481 cccagaccag tgaccaggat ggatcttggt tttttgatcc gcatctgcct atctttcagg
     6541 ggattcgatt aactcaccag cccagtcctt ggattgggga ctactcttgg ctccttctga
     6601 cacctgtcac cagtcaactg gggggagaca gcctctttca ccgccagtct tcttatgata
     6661 tagataaagc ttgcttccag cctcactatt tgaagctctt ttctctgcgt tatcagattg
     6721 aaacccagct cacaccaact tgctatggtg cttctattcg tttgaatcaa aagcaaggca
     6781 aagccctctc cctctatctt cacgcagcag atgaactgac agtagagcaa gtagataagc
     6841 ggactcttgc cctgcgacaa gaaggtaaaa ctgaaactaa caaaaattcg ctaacgatgt
     6901 tcactgccct gcaaatgaac acggatattc ttgctatcag ccaagaagct ggagactggc
     6961 gaattgactt agtaagtagt caaaccgaga tgcaactagc cacttctttc atctctcctt
     7021 ctcaagctct aatcaatcta cctcaagaag attttgatag ctgtaaatca agtgcccaag
     7081 cggattggga aaatctcctc catcgttttg acattataga gacaggagag gctgaccgaa
     7141 ccttctttga ccactgcctc tacagactct tcctcttccc acagactttt tatgaggttg
     7201 atgagtcagg gcaagccatc cacatggatc tggctactgg tactgtcaag cctggtgtcc
     7261 tctttagcaa caatggtttc tgggatacct tccgcaccac cttccccctc tttgccctta
     7321 tcataccgga gcactatcaa cgctttttag aaggtttcct caatagctac cgcgatactg
     7381 gtttccttcc aaaatggctg gctccagatg aacggggtat gatgccaggt acacttttag
     7441 acggtattat cgcagatagc gcctgcaagg acatggcccc tgacctagaa ggagaactct
     7501 tccaagccat gctcgaaaca gccagcaaag ccgaccctct cggcatcaat ggccgccacg
     7561 gactagccca ataccaagaa ctaggttacc tctctaccga ccaccacgaa agtgttagcc
     7621 atactctaga ctatgcctat agtgactttt gtatcgccag ctgtgccaaa aaactagaga
     7681 acatagaaat cgctgaaacc tacaaggctg cttcacaaaa ttaccgccag ctatttgacg
     7741 ctgagacagg ttacatgcga gcacgagaca atcaaggaaa ctttcaccct gacttctctc
     7801 cttatagttg ggggcgagac tacgctgaat gctctgccat tcaagctact ttaggcgttc
     7861 tccacgacat ccctggctta atccaactga tgggtggaaa agaaaccttt agcaactatc
     7921 ttttgaaaac ctgtcaagat gctcccctct ttgaaacaac aggctatggt tacgaaattc
     7981 acgaaatgag cgagatggct actgctcctt ttggacaaat agccatttcc aaccagccta
     8041 gtttccacat tccttatctc ttccgttaca gcgattaccc tgactacact gcccttctta
     8101 tcaagacgct ccgtcagaaa gcttttcacc caagttggga agcctatcct ggagatgaag
     8161 acaatggtag tctctctgct tggtacatct ggtcagctct cggattttat ccaacctgtc
     8221 caggaaaacc aagctatgac ctcggaatcc ctctctttga ccatctacga gtctacctcg
     8281 ctaaagaaga taaatggctg gatatccata ctaaacaaaa ccacaaccat tttaactttg
     8341 tcaaagaatg ccgactggac aaaacactcg tatcaactat tcaacaccaa gacctcttaa
     8401 aagctgaaca actaactttc accctcagct ggttaccaag tcactaataa ccaaaagaac
     8461 ctttgcatcg cgcaaaggtt cttcttttat gaaacttgga cttgaagttg atccacaagc
     8521 tgaccatcca ccgttaggtt cagatagaaa tccaaggttt tatctcctgc gaaatacagg
     8581 gttggtagat gcaaatcttt tttgctttcc cctgcttgga attgaaggac ataaatctcg
     8641 tcctgatagg cgacaccatg gacacctgtc cccggttgaa tcgaaatctt agcttctaaa
     8701 ggaccactac attctctgcg cttaactgta aaataggcat tttctccctt tgccacagct
     8761 aggctttttt ctgcaaatgc tagttcctga acaacttctt tttttgataa ttcaggagtt
     8821 ttataaaggg aaatcttggt caatacagga atagattgtg cctcggtaat catcacgcgc
     8881 accttctgtg cctctactag cggacctcgc aagaggcgct tatgaccaac tgtgaagccc
     8941 ctgccaaatt cctgccagac accatccacc tctacttgca catgaaaagc agcgattcgt
     9001 tgccctagct tcaaatcttc tcttaactca attacatcaa aagttttagg agaacctaag
     9061 tcgagttcta actggatggg caagtctgca tcgtttgccc aagagctggt ctcaaggccg
     9121 tctgtcaaat ggcgacaagc aaagtctgcg gaaagagctg gaccagatac ctcagctccc
     9181 agagccaaat cttctttata gagctcattg cgataggtcg caaattcata aagtcgttca
     9241 atatcctttg catcaaagag cccagcttga ttcggcggaa tattaagcaa gagtggagtt
     9301 cctcgcccta ctgagtgaaa gtagatttcg accaactcct cgagagactt aggatcctga
     9361 tcctcatggt agaaccagcc tggacggatg gaaacatctg cctctccgat tgaaaaaatc
     9421 gtgcccgagg gatccccgtg ctgaagatag tccagctctg cttctgttcc tagtttatca
     9481 ggattcacct tttgccacag tggatcacct gcataccctc gttcattgcc aatccagcgg
     9541 atactggtgc cttctgttga aaaaatcaaa caatcgccct gcaagtcacg aatggtttca
     9601 aaccattttt caaattcata attgacctgc tgggcccctt cccctctagc accatccatc
     9661 caaacctcag cgaacttacc agcattccca tagttaggat ttgataagat ttccttcaac
     9721 tgagccagat aataggcatt gtagtccgct tctcggtcca catgatagag gggactatgg
     9781 gcatcccacg gtgacaggta gacccccata tccatatcaa actctgtggc agcttgggat
     9841 acttcaagga gcaagtcgcc ctttcctctc ctccaaggac tgaccttaac cgaataatct
     9901 gtgtgagctg tcggataaag gacaaagcca tcgtggtgct tgaccaccaa aatcaacttt
     9961 ttgaagcccg tttccttgag cacacgaacc cactcacgcg catccaactg actcgggtta
    10021 aagcgctcag gatcctcctg acctgttccc cattcctgat tataaaaagt attaggtcca
    10081 aaatggataa aggctgctag ttcatctccc agataagcta gctgagtctg acttggtaac
    10141 ggtccatgcg gtttgatttt cttcatcgtt atatatctcc ttcttttgca acttctcttg
    10201 ttcacaaggt tatccacagg ttgtggataa taaaccatga tctaacagcc agctctttcc
    10261 aactccaact ggtaggctca ggatttttct cctcaatatt ccctcttcaa acagctctgt
    10321 catatggttc tgctaacacc tctcagaatg ctactctcca taattattct caggcttctt
    10381 tcaggtcatt gtgtgaagac cattcactct ccagactttt ccacagattg tgaataagtg
    10441 attattctaa actatcacct cgtcgactat aacaaaaaat aaaaagaggg tcaataagat
    10501 aattatctct tcctaaatac tcagaaaaga ttctataatt tgtacaattg aacaagaaat
    10561 gcttctccaa aatctatctt caaaagaatg ttgcatcttt ttatcctttc acacaaacat
    10621 ttctctttat acagatccaa gtgataacca gatgataatt ggacactttt tggttatttg
    10681 tgtatttttt gaaaaatttt ttaaaaaaat tttatatcct ctttaataga agtttatgca
    10741 tttgtatata tgtattccat cctatgttgt gtataataac ataaaattgt gctaaatatc
    10801 ataatttata ttattttccg agaaattata gccattgaca ttacctagga attgcgttat
    10861 aacatacatg taagcggtac ccaaaatggt gccaagtcaa aatttttaag gaggaaaata
    10921 catgtcttca catccaattc aggtcttctc agaaattggg aaactgaaaa aagttatgtt
    10981 gcaccgtcca ggcaaggagt tagaaaactt gttgccggac tatcttgaaa ggcttctttt
    11041 tgatgatatt cctttcttgg aagatgctca aaaagaacat gatgcatttg cccaagctct
    11101 tcgcgatgaa ggaattgagg ttctctacct agaacaactc gctgctgaat cattgacctc
    11161 tccagaaatc cgcgatcaat ttatcgagga atacttagac gaagccaaca tccgtgatcg
    11221 tcaaactaag gttgctattc gtgaattgct tcacggcatc aaggacaacc aagaattggt
    11281 tgaaaaaaca atggctggga ttcaaaaagt tgaattgcca gaaattcctg acgaagctaa
    11341 agatctaact gacttagttg aatcagatta tccatttgca attgacccga tgccaaacct
    11401 ctatttcact cgcgacccat ttgcaacaat tggaaacgcc gtatcgctta accacatgtt
    11461 tgcagacact cgtaaccgtg aaacactcta cggtaagtat atcttcaaat accacccaat
    11521 ctatggcgga aaagtggatt tggtctacaa ccgtgaagaa gatacgcgta tcgaaggtgg
    11581 agacgagcta gttctttcta aagacgtcct tgcagtaggt atctctcaac gtacagacgc
    11641 agcttctatc gaaaaacttt tggtcaacat cttcaagaaa aatgttggct tcaagaaagt
    11701 tttggccttt gaatttgcta acaaccgtaa attcatgcac ttggatactg tcttcactat
    11761 ggtagactat gacaagttca ctattcaccc agaaatcgaa ggcgaccttc acgtttactc
    11821 agttacttac gaaaacgaaa aacttaaaat tgttgaagag aaaggtgact tagctgaact
    11881 tcttgctcaa aaccttggtg tagaaaaagt tcatttgatt cgttgcggtg gtggcaatat
    11941 cgtagcagct gcgcgtgaac aatggaacga cggttctaac actttgacca tcgcacctgg
    12001 tgtggtagtt gtttatgacc gcaataccgt gaccaataag attttggaag aatacgggct
    12061 tcgcttgatt aagattcgcg gaagtgaatt ggttcggggc cgtggtggac ctcgttgtat
    12121 gtctatgcca tttgaacgtg aagaagtgta atcgctgttc ggtattcgtc aatagaaaat
    12181 gtaaaaaata gaaagaggaa ataataaaat gacaaattca gtattccaag gacgcagctt
    12241 cttagcagaa aaagacttta cccgtgcaga gttagaatac cttattggtc tttcagctca
    12301 cttgaaagat ttgaaaaaac gcaatattca acaccactac cttgctggca agaatatcgc
    12361 tctcctattt gaaaaaacat ctactcgtac tcgtgcagcc tttacaactg cggctatcga
    12421 ccttggtgct cacccagaat acctcggagc aaatgatatt cagttgggta aaaaagaatc
    12481 tactgaagat actgctaaag tattgggacg tatgtttgac gggattgaat tccgcggatt
    12541 cagccaacgt atggttgaag aattggcaga attctcaggc gttccagtat ggaacggtct
    12601 aactgacgaa tggcacccaa ctcaaatgct cgctgactac ttgactgttc aagaaaactt
    12661 cggtcgcttg gaaggcttga cattggtata ctgtggtgat ggacgtaaca atgttgccaa
    12721 cagcttgctc gtaacaggtg ctatccttgg tgtcaatgtt cacatcttct caccaaaaga
    12781 actcttccca gaaaaagaaa tcgttgaatt ggcagaagga tttgctaaag aaagtggcgc
    12841 acatgttctc atcactgaag atgctgatga agcagttaaa gatgcagacg ttctttacac
    12901 agacgtttgg gtatcaatgg gtgaagaaga caaattcgca gaacgtgtag ctcttcttaa
    12961 accttaccaa gtcaatatgg acttagttaa aaaagcaggc aatgaaaact tgatcttcct
    13021 acactgcttg ccagcattcc acgatactca cactgtttat ggtaaagacg ttgctgaaaa
    13081 atttggtgta gaagaaatgg aagtaacaga cgaagtcttc cgcagcaagt acgctcgcca
    13141 cttcgatcaa gcagaaaacc gtatgcacac tatcaaagct gttatggctg ctacacttgg
    13201 taacctttat attcctaaag tataatttta gataataaac cgtctaccaa cagctatgag
    13261 ggctgcgact aatagcttta gtccggtcct cttttatgta atggtaatct attatttctt
    13321 ataaaatatg tgaaaaatca ttaaattgaa atctaaacgc attctattga gtgtgataaa
    13381 ggagaattta tggcaaatcg taaaattgta gtagctttgg gaggaaatgc gattctttct
    13441 tctgacccat cagcaaaggc tcaacaagaa gctttagttg aaacagctaa gcatcttgta
    13501 aaattgataa aaaatggaga tgatctgatt atcactcacg gtaatggacc tcaagttggg
    13561 aatctcttgc tccaacattt ggcatcagac tctgaaaaga accctgcctt cccactcgac
    13621 tcacttgtcg ctatgacaga aggtagcatc ggtttctggt tgaaaaatgc tttgcaaaat
    13681 gctctcttgg atgaaggcat cgaaaaaaat gttgcctctg ttgtaacgca agttgtcgta
    13741 gataaaaatg atccagcttt tgttaacttg agtaaaccaa tcggtccttt ctattcagaa
    13801 gaagaagcaa aagcagaagc cgaaaagagc ggagcgactt tcaaggaaga tgctggccgt
    13861 ggctggcgta aggtcgttgc ctcaccaaaa cctgttgaca tcaaagaaat tgaaaccatc
    13921 cgtactcttt taaataatgg tcaagtcgtc gtagctgcag gtggtggcgg tattcccgtc
    13981 gtcaaagaaa acaatggaca tttgactggt gtcgaagcgg ttattgataa agacttcgct
    14041 tcccaacgtt tggcagaatt ggttgatgca gacctcttca tcgttttgac aggtgtagat
    14101 tatgtatttg ttaactacaa caagccaaac caggaaaaat tggaacatgt gaatgttgcc
    14161 cagctagaag aatatatcaa acaagatcag tttgcaccag gtagcatgct tccaaaagta
    14221 gaagcagcta tcgcttttgt caatggtcgt ccagaaggaa aagcagttat tacttccctt
    14281 gaaaatctag gcgccttgat tgaatctgaa agcggaacaa ttattgaaaa aggataagtt
    14341 gttttactaa taagatgtat tctatttcta gtatctttat atcaaattag aaattattct
    14401 tgaaaacatg tacaatattt caaaagatat tagtttttta gactttaata tggtaaaaca
    14461 aatataaata gaaagcgttt tcttaaatgt ttatttaaga aagtagttgg ttttttacac
    14521 tttgttagac atcaggagga aaaacaaatg agtgaaaaag ctaaaaaagg gtttaagatg
    14581 ccttcatctt acaccgtatt attgataatc attgctatta tggcagtact aacttggttt
    14641 atccctgcgg gggcctttat agaaggtatt tacgagactc agcctcaaaa tccacaaggg
    14701 atttgggatg tcctcatggc accgattcgg gctatgctag gtactcatcc agaggaaggt
    14761 tcgctcatta aagaaacgag cgcagcgatt gatgtagcct tcttcatcct tatggttggt
    14821 ggtttccttg gcattgtcaa caaaactggt gctcttgacg tagggattgc ctctatcgtg
    14881 aagaagtata agggccgcga aaaaatgtta attttggtac taatgccttt gtttgccctc
    14941 ggtggtacaa cttatggtat gggtgaagaa acaatggcct tctatccact ccttgtgcca
    15001 gttatgatgg ccgttggttt tgatagcctg actggtgttg caattatttt gctcggttct
    15061 caaatcggct gtttggcatc tactctgaat ccatttgcga caggtattgc ttcagcgact
    15121 gcgggagttg gtacagggga cggtatcgta cttcgtctga ttttctgggt taccttgact
    15181 gctcttagta cttggtttgt ttaccgttat gcggataaga ttcaaaaaga tccgactaag
    15241 tcactggttt atagtactcg caaagaagat ttgaaacact ttaacgtaga agaatcttca
    15301 tctgtagaat ctacacttag cagcaaacaa aaatcagttc tcttcttatt tgtgttgaca
    15361 ttcatcttga tggtattgag cttcattcca tggacagacc ttggcgttac catttttgat
    15421 gactttaatg cttggttgac tggtcttcca gttattggta atattgtcgg ttcatctact
    15481 tctgcactag gtacttggta cttcccagaa ggcgcaatgc tctttgcctt tatgggtatc
    15541 ctgattggtg ttatttatgg tcttaaagaa gataagatta tctcttcctt catgaatggt
    15601 gctgctgact tgctcagtgt tgccttgatc gtagcgattg ctcgtggtat tcaagttatc
    15661 atgaacgacg gtatgattac cgatacaatc ctcaactggg gtaaagaagg cttgagcgat
    15721 ctatcttcac aagtctttat cgttgtaact tatatcttct atctacctat gtcattcttg
    15781 atcccatctt catctggtct tgccagcgca actatgggta tcatggctcc acttggagaa
    15841 tttgtaaatg tccgtcctag cttgattatc actgcttacc aatctgcttc aggtgtcttg
    15901 aacttgattg caccaacatc tggtattgtg atgggagctc ttgcacttgg acgtatcaac
    15961 attggtactt ggtggaaatt catgggcaaa ctcgtagtcg ctattattgt agtgaccatc
    16021 gcccttcttc tccttggaac cttccttcca ttcctataaa atagtgagtg aggtgattcc
    16081 atgaaaatag atataacaaa tcaagttaaa gatgaatttc ttatatcatt aaaaaccttg
    16141 atttcctatc cttcagtact caatgaagga gaaaatggaa caccttttgg acaagcaatc
    16201 caagatgtcc tagaaaaaac tttagagatt tgtcaagaca taggtttcac tacctatctt
    16261 gaccctaaag gttattacgg atatgcagaa atcggtcagg gagcagagct tctggccatt
    16321 ctctgtcatt tggatgttgt tccatcaggt gatgaagcag attggcagac accgccattt
    16381 gaagcaacta tcaaagacgg ctgggtattc ggacgtggtg tccaagatga taaaggccct
    16441 tcgctcgcag ctctttatgc agtaaaaagc ttgctggacc aaggtattca gttcaaaaag
    16501 cgcgtacgct ttatctttgg taccgatgag gaaaccctct ggcgctgcat ggcacgctac
    16561 aataccatcg aagaacaggc cagcatgggc tttgcacctg actcatcttt tcctctgacc
    16621 tatgctgaaa aagggcttct acaggtcaaa cttcatggcc ctggatcgga tcaactagag
    16681 cttgaagtag gaggcgcctt taacgttgta ccagacaagg ccaactacca aggtcccctc
    16741 tatgaacagg tttgtaacga tctcaaagaa gctggttatg attaccaatc cactgaacaa
    16801 accgtaacgg ttctcggagt gccaaagcat gctaaggatg ctagtcaagg tatcaatgct
    16861 gtcatccgac tagctaccat tcttgctcct ctccaagaac accctgctct cagctttctt
    16921 gcaacacaag caggtcaaga cggcacagga agacaaatct ttggtgatat agcagatgaa
    16981 ccttctggtc acctatcctt taatgtcgca ggtctcatga tcaatcatga acgttctgaa
    17041 atccatattg acattcggac tcctgtctta gctgataagg aagaactagt agagttgctt
    17101 agaagatgtg cacaaaacta ccaactccgc tacgaagagt ttgactatct agcgcctcta
    17161 tacgtcgcaa aagacagtaa actcgttagc acactgatgc aaatctacca agaaaagact
    17221 ggcgataaca gtcctgctat ttcatccggt ggtgccactt ttgctcgcac catgccaaat
    17281 tgtgtagcct tcggcgcctt attcccagga gcaaagcaga cagaacatca ggcaaatgaa
    17341 tgtgccgttc tagaagattt gtaccgtgct atggatattt atgccgaagc cgtctatcga
    17401 cttgcaactt aatcaggcaa ctgtttctac caaaaaaaat cgaccgatta atgaactgca
    17461 ccccaaaagt tagacagaa
//
LOCUS       DAVHTH010000040        17381 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.040, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000040 DAVHTH010000000
VERSION     DAVHTH010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17381)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17381)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17381
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.040"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            complement(<1..1468)
                     /locus_tag="VVR63_001467"
     CDS             complement(<1..1468)
                     /locus_tag="VVR63_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEU6129476.1"
                     /translation="MKINKKYLVGSAAALILSVCSYELGLYQARTVKENNRVSYIDGK
                     QATQKTENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIFSEE
                     LLMKDPNYKLKDEDIVNEVKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QYREGGTPRNDGAVALARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAAEAFLSGRGNLSNSRTYRRQNSDNTSRTNWVPSVSNPGTTNTNTSNNSN
                     TNSQASQSNDIDSLLKQLYKLPLSQRHVESDGLIFDPAQITSRTARGVAVPHGDHYHF
                     IPYSQMSELEERIARIIPLRYRSNHWVPDSRPEQPSPQSTPEPSPSPQSAPNPQPAPS
                     NPIDEKLVKEAVRKVGDGYVFEKNGVSRYIPAKNLSAETAAGIDSKLAKQESLSHKLG
                     TKKTDLPSSDREFYNKAYDLLARIHQDLLDNKGRQVDFE"
     gene            complement(1722..3455)
                     /gene="ptsP"
                     /locus_tag="VVR63_001468"
     CDS             complement(1722..3455)
                     /gene="ptsP"
                     /locus_tag="VVR63_001468"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HEU6129477.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARL
                     DAALQASQDELSVIREKAVGTLGEEAAQVFDAHLMVLADPEMISQIKETIRAKKVNAE
                     AGLKEVTDMFITIFEGMEDNPYMQERAADIRDVTKRVLANLLGKKLPNPASINEEVIV
                     IAHDLTPSDTAQLDKNFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNNITEIVKDGD
                     ILAVNGITGEVIINPTDEQAAEFKAAGEAYAKQKAEWALLKDAQTVTADGKHFELAAN
                     IGTPKDVEGVNNNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDMPHEMNPFLGFRALRISISETGDAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAVFDEEKANLLAEGVAVADNIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDTAKMEEYANRALTECSTMEEV
                     LELQKEYVNFD"
     gene            complement(3461..3724)
                     /locus_tag="VVR63_001469"
     CDS             complement(3461..3724)
                     /locus_tag="VVR63_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HEU6129478.1"
                     /translation="MASKDFHVVAETGIHARPATLLVQTASKFASDITLEYKGKSVNL
                     KSIMGVMSLGVGQGADVTISAEGADADDAIAAISETMEKEGLA"
     gene            4075..4293
                     /gene="nrdH"
                     /locus_tag="VVR63_001470"
     CDS             4075..4293
                     /gene="nrdH"
                     /locus_tag="VVR63_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000259243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HEU6129479.1"
                     /translation="MVTVYSKNNCVQCKMTKRFLDSNNVSYREINLDEQPEYVDQVKE
                     LGFSAAPVIQTPTEVFSGFQPGKLKQLA"
     gene            4374..6533
                     /gene="nrdE"
                     /locus_tag="VVR63_001471"
     CDS             4374..6533
                     /gene="nrdE"
                     /locus_tag="VVR63_001471"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HEU6129480.1"
                     /translation="MGLKHLEDVTYFRLNNEINRPVNGQIMLHKDKEALDAFFKENVV
                     PNTMVFDSIKDKINYLIEHNYIETAFIKKYRPEFLEELAQFIKDQNFQFKSFMAAYKF
                     YNQYALKTNDGEYYLENMEDRVFFNALYFADGNEAVAIDIANEIIHQRYQPATPSFLN
                     AGRARRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGVVVPDKFYELARKNEEMYLFSPYSVEKEYGVPFNYIDITEKYDELVANPNI
                     RKTKIKARDLETEISKLQQESGYPYVVNIDTANRANPVDGKIIMSNLCSEILQVQEPS
                     LINDAQEFLQMGTDVSCNLGSTNVVNMMTSPDFGRSIRAMVRALTFVTDSSHIVAVPT
                     IDHGNSQAHTFGLGAMGLHSYLAQQLIEYGSPESVEFTSIYFMLMNYWTLVESNNIAR
                     ERGITFHNFEKSDYANGSYFDKYVTGEFVPTSDRVKELFKNVFIPGVADWAELRDKVQ
                     EDGLYHQNRLAVAPNGSISYINDVSASIHPITQRIEERQEKKIGKIYYPAAGLSTETI
                     PYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFMRSDIPKGLYEWKRENKQTTRDLS
                     ILRNYAFNKGIKSIYYVRTFTDDGGEVGANQCESCVI"
     gene            6721..7683
                     /gene="nrdF"
                     /locus_tag="VVR63_001472"
     CDS             6721..7683
                     /gene="nrdF"
                     /locus_tag="VVR63_001472"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HEU6129481.1"
                     /translation="METYYKAINWNAIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSNKEKDLVGKVFGGLTLLDTMQSETGVQALRADIRTPHEEAVFNNIQFMESVHAK
                     SYSSIFSTLNTKAEIEEIFEWTNTNPYLQKKAEIVNEIYLNGSPLEKKVASVFLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEEEQEKLK
                     EWMYDLLYTLYENEEGYTESLYDGVGWTEEVKTFLRYNANKALMNMGQDPLFPDSAED
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGEVEAMQDDDYNYGLD"
     gene            7971..8732
                     /locus_tag="VVR63_001473"
     CDS             7971..8732
                     /locus_tag="VVR63_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000917571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEU6129482.1"
                     /translation="MLKQEKLTKILEIVNSKGTITVKQIMDEIAVSDMTARRYLQELA
                     DKDLLIRVHGGAEKLRTNSLLTNERSNIEKQALQTAEKQEIAHFAGSLVEERETIFIG
                     PGTTLEFFARELPIDNIRVVTNSLPVFLILSERKLTDLILIGGNYRDITGAFVGTLTL
                     QNLSNLQFSKAFVSCNGIQNGALATFSEEEGEAQRIALNNSNKKYLLADHSKFNKFDF
                     YTFYNISNLDTIVSDSKLSDSILFKLSKHIKVIKP"
     gene            complement(8843..9052)
                     /locus_tag="VVR63_001474"
     CDS             complement(8843..9052)
                     /locus_tag="VVR63_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000471575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HEU6129483.1"
                     /translation="MFKDFIQSIYEKVYIINFEKCSQIPCLTSEELKSLGKWYVSTGK
                     EWICHSDDDLEEFKNLFLNFINPEE"
     gene            complement(9095..10501)
                     /gene="lacG"
                     /locus_tag="VVR63_001475"
     CDS             complement(9095..10501)
                     /gene="lacG"
                     /locus_tag="VVR63_001475"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HEU6129484.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLKLAEEYGVNGIRISIAWSRIFPTGYGQVNVKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEALHSNGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLYKEKGYKGEIGVVHAL
                     PTKYPLDHENPADVRAAELEDIIHNKFILDATYLGHYSEKTLAGVEAILAANGGSLDL
                     REEDFTALEAAKDLNDFLGINYYMSDWMEAFDGETEIIHNGKGEKGSSKYQIKGIGRR
                     VAPDYVPRTDWDWIIYPQGLYDQIMRVKKDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKQHLEVLSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFETQERY
                     PKKSAHWYKKVAETQIID"
     gene            complement(10716..12410)
                     /locus_tag="VVR63_001476"
     CDS             complement(10716..12410)
                     /locus_tag="VVR63_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEU6129485.1"
                     /translation="MDKLIIFIEKGKPFFEKLSRNIYLRAIKDGFISSMPAVLFSSIF
                     ILIAAVPNIFGFKWSDEQLAFILKPYNYSMGILALLVAGTTAKSLTDSVNTRSMEKTN
                     QINYMSTFLAAVVGLLILAADPIEGGFANGLLGTRGLLTAFLAAFITVNIYKVCIKNN
                     VTIRLPEEVPPNIAQVFKDVIPFALSVLSIYGLDLIVRNIFGTNVAESVGKILAPLFS
                     ATDGYIGLAIVFGAYAFFWFVGIHGPSVVEPLIVAISYANIEANVQLVQAGMHADKIL
                     NPVTQTFVVTMGGTGATLVVPFMFMWLCKSKRNRIVGRASVVPTFFGVNEPILFGAPI
                     VLNPIFFIPFVTAPIINVWIMKFFVDVLQMNSFSIILPWTTPAPIGIVMGTALAPLSF
                     VLAITLIIIDTLIYYPFVKVYDHQILEEERKGNSSSELKEKVAANFNTAKADAILEKA
                     GVDAAQNTITEETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGGYGAHREMLP
                     EFNLVILAPQVASNFEDMKAETDKLGIKLAKTEGAQYIKLTRDGKGALAFVQEQFD"
     gene            complement(12412..12729)
                     /locus_tag="VVR63_001477"
     CDS             complement(12412..12729)
                     /locus_tag="VVR63_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEU6129486.1"
                     /translation="MNREEVTLLGFEIVAYAGDARSKLLEALKAAEAGDFEKADALVE
                     EAGSCIAEAHHAQTSLLTKEASGEDLAYSVTMMHGQDHLMTTILLKDLMHHLIELYKR
                     GVK"
     gene            complement(12765..13601)
                     /locus_tag="VVR63_001478"
     CDS             complement(12765..13601)
                     /locus_tag="VVR63_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEU6129487.1"
                     /translation="MYRILNPMNHNVSLVRNDKGEEVIVIGKGIAFGKKKGDLIAENH
                     VEKIFRMKTEESRENFMALLKDVPLDFITVTYEIIDKLSKKYHYPIQEYLYVTLTDHI
                     YCSYQALTQGRYKDSNLPDISAKYPVAFQIANEAFEIYCQKLADHFPEDEIIRIAYHF
                     INAEGENEVELVESIDKRKEILRNVEEVLTDYAIQRTKKNNHFYDRFMIHLNYFLDYL
                     DRSRDDNQSLLDMEDHIKQSYPKAFEIGSKIYDVITQHTGLDLYKSERVYLVLHIQRL
                     LS"
     gene            complement(13835..14815)
                     /gene="lacD"
                     /locus_tag="VVR63_001479"
     CDS             complement(13835..14815)
                     /gene="lacD"
                     /locus_tag="VVR63_001479"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HEU6129488.1"
                     /translation="MALTEQKRVRLEKLSDENGIISALAFDQRGALKRLMAQHQTEEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPATKALDEKAGLLLAYEKTGYDTTSTK
                     RLPDCLDVWSAKRIKEEGADAVKFLLYYDVDSSDELNQEKQAYIERIGSECVAEDIPF
                     FLEILAYDEKIADAGSVEYAKVKPHKVIGAMKVFSDPRFNIDVLKVEVPVNIKYVEGF
                     AEGEVVYTREEAAAFFKAQDEATNLPYIYLSAGVSAKLFQDTLVFAHESGANFNGVLC
                     GRATWAGSVEAYIKDGETAAREWLRTTGFENIDELNKVLQTTATSWKERV"
     gene            complement(14817..15746)
                     /locus_tag="VVR63_001480"
     CDS             complement(14817..15746)
                     /locus_tag="VVR63_001480"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HEU6129489.1"
                     /translation="MILTVTMNPSIDISYPLDELKIDTVNRVVDVTKTAGGKGLNVTR
                     VLSEFGDSVLATGLVGGKLGEFLVEHIDNQVKKDFFSIQGETRNCIAILHGDNQTEVL
                     EKGPEVLEQEGQDFLEHFKKLLESVEVVAISGSLPAGLPVDYYASLVELANQAGKPVV
                     LDCSGAALQAVLESPHKPTVIKPNNEELSQLLGREVSEDLDELKEVLQEPLFAGIEWI
                     IVSLGANGTFAKHGDTFYKVDIPRIQVVNPVGSGDSTVAGISSGLLHKESDAELLIKA
                     NVLGMLNTQEKMTGHVNMANYQALYDQLIVKEV"
     gene            complement(15757..16272)
                     /gene="lacB"
                     /locus_tag="VVR63_001481"
     CDS             complement(15757..16272)
                     /gene="lacB"
                     /locus_tag="VVR63_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HEU6129490.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGYEVIDFGTYDHTRTHYPI
                     FGKKVGEAVTSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTTALYAKEQLNAN
                     VIGFGGKITGELLMCDIIEAFIHAEYKPSEENKKLIAKIEHLESHNAQQTDANFFTEF
                     LEKWDRGEYHD"
     gene            complement(16303..16728)
                     /gene="lacA"
                     /locus_tag="VVR63_001482"
     CDS             complement(16303..16728)
                     /gene="lacA"
                     /locus_tag="VVR63_001482"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HEU6129491.1"
                     /translation="MSIVIGADAAGLRLKEVVKDFLEKENFHLVDVTAEGQDFVDVTL
                     AVAAEVNKEEQNLGIVIDAYGAGSFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     MGAQLVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMG"
     gene            complement(16886..17350)
                     /locus_tag="VVR63_001483"
     CDS             complement(16886..17350)
                     /locus_tag="VVR63_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase"
                     /protein_id="HEU6129492.1"
                     /translation="MGGHPGFNCLLLDDEVYEDYYLEFEKEEICSVPRPFPETGMLDF
                     QDRSPWLEGQKEIDLSYDLFSTDAVTLDELQSRTIALRSLKHDKGLKVHFAEFPNLII
                     WSTLNKGPFITFEPWSGLSTFLEEGDHLEDKKNVCLLEANQVEELGFEIEVL"
BASE COUNT         5193 a         3609 c         3097 g         5482 t
ORIGIN      
        1 cctcaaaatc aacttgtcga cctttattat caagtaaatc ttggtgaatt cttgctagta
       61 agtcataagc cttattgtaa aattctctat cactagatgg gaggtcagtt ttcttagttc
      121 ctagcttatg agataaactt tcctgcttgg ccagtttgct atcaatgcct gctgctgttt
      181 ctgctgaaag attcttggct gggatataac gagaaactcc attcttctca aagacataac
      241 catcgcctac ttttcgaaca gcttctttga ccaatttctc atcaattgga ttgcttggag
      301 ctggttgagg atttggtgca gattgcggac ttggactagg ttctggagtc gattgtggac
      361 ttggttgttc tggtcttgaa tctggtaccc aatggtttga acgataacga aggggaataa
      421 tacgagcaat tcgttcttcc aattcagaca tttgagagta agggatgaag tggtaatgat
      481 ctccgtgtgg cactgcaaca cctctagctg ttcgacttgt gatttgcgct gggtcgaaaa
      541 taaggccatc agattccaca tggcgttgac tcaaaggcag tttgtagagc tgtttcaaga
      601 gactatcaat gtcattactt tgacttgctt gactgttagt gttgctgttg ttgcttgtgt
      661 tagtatttgt agttcctgga ttgcttacag aaggtaccca gtttgttctt gaagtgttat
      721 cgctattttg tcggcgatag gttcttgaat ttgacagatt tccccgacca gataggaagg
      781 cttctgcagc agccaactcg ctagctgata actcattctt aggaatgtaa tggtaatgat
      841 ctccatgagg aacgatataa gcatcaccag tatcctctat gatatcagaa gcattaaaga
      901 tataaccatc atctgtagta tagcgtcctt gcgaacgtgc caaggcaaca gctccatcgt
      961 ttcttggagt ccctccttca cgatactgac tatgttcttg tttttgtcga ttgatttcct
     1021 cttttgtacg gacgttatcc gcgtgggcag catccttaag gtaaacatag tattttccat
     1081 ctaccttgat aacatatcca cccttgacct cattaacaat atcctcatct tttagcttat
     1141 agtttggatc tttcatgagt aattcttcac tgaaaatcgc atcataagga accttaccat
     1201 tgtaataatg atagtggtcg ccatgtgaag tgacatagcc ttggtctgtt atcttgatga
     1261 cgatttgctc agcattgatt ccttcacgct tgctaacctc atcaggagtc aaattctccg
     1321 ttttttgcgt cgcttgtttt ccatctatat aggaaacacg attattttcc ttaaccgttc
     1381 tagcttgata cagtcccaac tcgtaagaac aaacacttaa aatcaaagct gccgcagaac
     1441 caacaaggta tttcttatta attttcatcg aaactctctt tctatttgat atttctagtt
     1501 gcaattcatt tctaaattgc agaaactcct ctctattact taactggtta atagtttact
     1561 cctaaatctc caacttgtca agaattttat gaaccattta agtatttttt gttctgacca
     1621 ctactttttc aaggttggac tttctataaa aaagattttc ttgaaaattc tttttaaaat
     1681 atcaaaaaaa tccctgtaac tgagttgcag ggacttgtcg attaatcaaa attaacgtat
     1741 tctttttgaa gttcaagaac ttcttccatt gttgagcatt ctgtaagggc acggtttgcg
     1801 tactcttcca tcttagctgt gtcgagtttc ttcatcaagc tgcgtgtacg aagtacagat
     1861 gttgctgaca tagagaactc atccaagccc attccgacaa gaagtggaac agcttgttgg
     1921 tcaccagcca tctcaccaca cataccagcc catttacctt cagcgtgagc tgctttgatc
     1981 acattgttaa tcaagcgtag gattgatggg ttgtatggtt ggtaaaggta tgaaacttgt
     2041 tcgttcatac ggtctgctgc cattgtatat tggatcaagt cgtttgtacc aattgagaag
     2101 aagtcaactt ctttagcaaa ttggtctgca agcatagccg ctgcaggaat ctcaatcatg
     2161 ataccaactt ggatgttatc cgcaactgca acaccttcag caagaaggtt tgctttttct
     2221 tcatcaaaga ctgctttcgc tgcacggaat tctttcaaga gcgcaaccat tgggaacatg
     2281 atacgcaatt gaccgtgaac agacgcacga agaagagcac ggatttgtgt gcggaacata
     2341 gcatctccag tctcagagat agagatacga agagcacgga atccaaggaa tgggttcatt
     2401 tcgtgaggca tatcgaagta aggaagttcc ttatctccac cgatatccat tgtacgaacg
     2461 acaacaggtt taccgttcat tccttcaaga acagccttgt atgcttcata ctgctcatct
     2521 tcagttggga agtcttgaga atccatgtac aagaactctg tacggtaaag tccaacagct
     2581 tctgcaccgt tgttgttaac accttcaacg tcttttggag taccaatatt ggcagccaac
     2641 tcgaagtgtt taccgtcagc agtcactgtt tgagcatctt tcaaaagtgc ccattcagct
     2701 ttttgtttcg cataggcttc accagctgct ttaaattctg ccgcttgttc atctgttggg
     2761 ttgataatca cttctccagt gatcccgtta acagcaagga tgtcaccgtc tttaacgatt
     2821 tcagtgatgt tatttgtacc taatacagca gcaatttcaa gtgtacgtgc catgatagct
     2881 gagtggcttg tacgtccacc aatgttggtt acaaaagctt ttacaaagtt tttgtccaat
     2941 tgagctgtat ctgaaggagt caagtcatgc gcaatcacaa tcacttcttc attgatagaa
     3001 gctgggtttg gcaatttttt accaagaagg tttgccaata cacgttttgt cacgtcgcgg
     3061 atatccgctg cgcgttcttg catgtatggg ttgtcttcca tgccttcaaa gatagtgata
     3121 aacatatctg taacttcttt cagacctgct tctgcattca ctttcttcgc acggatagtt
     3181 tccttgattt ggctgatcat ttctgggtca gcaagaacca ttaagtgagc atcaaaaact
     3241 tgagctgctt cttcaccgag cgtacctact gctttctcgc gaataacaga aagctcgtct
     3301 tgtgatgcct gtagagcggc atcaaggcga gcttcttctg cgtttgtatc ttcgactgta
     3361 atagtctcaa atgacaaatc cggctgaacg agtagatatg cttttgcaac tgcaacaccg
     3421 tcagatgctg cgattccttt aagcatttct gtcatttccc ttatgccaat ccttcttttt
     3481 ccattgtttc tgagattgca gcgatagcgt catctgcatc tgcaccttca gctgagatag
     3541 ttacgtcagc accttgacca acaccaagac tcataacacc cataattgat ttaaggttaa
     3601 ctgatttacc tttgtactca agagtgatat ctgaagcaaa tttgctagca gtttgtacca
     3661 acaatgttgc tggacgtgcg tgaatacctg tttctgccac tacgtggaaa tctttagaag
     3721 ccatagtttg actctccttt tgttctttct ttttttgagt tatatgtgat aacccttaca
     3781 atttagtatt ataccatctt ctaggatttt tttcaagcat tttctggatt ttccttcaat
     3841 ttcctttcag ataacttgct gaaaatcttc tatcctagat aacaaaacac aggatatagt
     3901 ttcttcaaaa acaatttata ggataatcat tgctatttca caatacaaac actatatatt
     3961 gtgtttatat ataaaaacaa caaaagaaca ccactatatt tagtttaaat cattgacaaa
     4021 attttatttt ctgatatact aagatagtat taaattttga agaggagtta cacaatggta
     4081 accgtttatt ctaaaaacaa ttgtgtccaa tgtaaaatga ccaagcgttt cttggacagt
     4141 aataatgtct cttatcgtga aatcaatctt gatgagcaac ctgagtacgt cgatcaagtt
     4201 aaagagctcg gttttagcgc agctcctgtt atccaaacac caactgaagt cttttcaggt
     4261 ttccaaccag gaaaactgaa acaattagca taatcttagt acatcatcca gaagaaactg
     4321 cttttagggc taacttagaa gcctttcttt tgtaattaga taagggaaat tttatgggat
     4381 taaaacatct tgaagacgtg acttacttcc gtcttaataa cgaaattaac cgtcctgtta
     4441 atggacaaat catgcttcat aaagataagg aagccttgga tgctttcttt aaagaaaatg
     4501 tagttccaaa cactatggtt tttgattcaa tcaaagacaa aatcaattac ctcattgaac
     4561 acaactacat cgaaacagcc tttatcaaga aataccgtcc agagttcttg gaagaattgg
     4621 ctcaatttat caaagaccaa aacttccaat tcaagtcatt catggcagct tataaatttt
     4681 acaatcaata tgccttaaag actaatgacg gtgaatacta tcttgaaaat atggaagacc
     4741 gtgtcttctt caacgccctt tatttcgctg atgggaatga agctgttgca atcgatattg
     4801 ccaatgaaat catccaccaa cgctaccaac ctgctactcc ttccttcttg aatgctggac
     4861 gtgctcgtcg tggggagttg gtatcttgtt tcctaatcca agtgacggat gatatgaact
     4921 ctatcgggcg ttctatcaac tcagctcttc aactttcacg tattggtggt ggtgtgggaa
     4981 ttaccctcag caaccttcgt gaagctggtg cacctatcaa aggctatgaa ggagctgctt
     5041 caggtgtcgt tcctgttatg aagctttttg aagacagctt ctcttactcc aaccaattgg
     5101 ggcaacgtca aggtgccggc gttgtctacc tcaacgtctt tcacccagat atcatcgctt
     5161 tcctttcaac taagaaagaa aacgctgatg aaaaagtacg tgtcaagact ctatcacttg
     5221 gtgttgtagt acctgataaa ttctacgaat tggctcgtaa aaatgaagaa atgtacctct
     5281 tcagccctta ctctgtagaa aaagaatacg gtgtgccatt caattacatc gacattactg
     5341 aaaaatacga tgaattggtc gcaaatccaa atattcgcaa gacaaaaatc aaggcgcggg
     5401 atttggaaac tgaaatctct aaattgcaac aagagtctgg ctatccttat gtagtcaaca
     5461 tcgatacggc taaccgtgca aatcctgttg atggaaagat tatcatgagt aacttgtgtt
     5521 ctgagattct tcaagttcaa gaaccaagct tgatcaacga tgctcaagaa ttccttcaaa
     5581 tgggaacaga tgtttcatgt aacctgggtt caaccaacgt ggttaacatg atgacttcac
     5641 ctgattttgg tcgttctatc cgtgctatgg ttcgtgccct tactttcgtt acagatagtt
     5701 cacatatcgt agctgtacca acgattgacc atggaaatag ccaagcccac acctttggtc
     5761 tcggtgccat gggactgcac agctaccttg cccaacaact cattgaatat ggttcacctg
     5821 agtctgttga atttacaagc atctacttta tgcttatgaa ctactggacc ttggtagagt
     5881 caaacaatat tgcacgtgaa cgtggtatta ccttccacaa ctttgaaaaa tcagactatg
     5941 ctaacggaag ttactttgac aagtatgtaa ctggtgaatt tgttccaaca tcagaccgtg
     6001 ttaaagaact cttcaaaaat gtttttatcc ctggtgttgc tgattgggct gaacttcgcg
     6061 acaaggttca agaagatggt ctttaccacc aaaatcgcct tgctgtagcg ccaaatggtt
     6121 ctatcagcta tatcaacgac gtttctgctt ctatccaccc gattacgcaa cgtatcgaag
     6181 aacgccaaga gaagaaaatt ggtaaaatct actaccctgc tgctggcttg tctacagaaa
     6241 ccattcctta ctacacttct gcctacgata tggatatgcg taaagtcatc gatgtttacg
     6301 ctgctgcgac tgaacacgtg gatcaaggac tttcactcac cctcttcatg cgcagtgaca
     6361 ttccaaaagg cctttacgaa tggaagaggg aaaataaaca aacgacacgt gatttgtcca
     6421 tccttcgtaa ctatgccttt aacaagggaa tcaagtctat ctactacgtc cgtaccttta
     6481 cagatgacgg tggagaagtc ggcgccaacc aatgtgaaag ctgtgtgatt tagtttctag
     6541 catagaaaca ttatttttcc ctaagcagca ctgataaaat caaatctact atgtcataat
     6601 ataatttatg taacatttta aaagtcgggc ttccgacttt ttgtgcgata ctcctataga
     6661 attatggtaa agtagaaata attgtgagtt cgcaatacta aacacagaaa gagattttaa
     6721 atggaaactt actacaaagc cattaactgg aatgccatcg aagatgtcat cgacaaatca
     6781 acttgggaaa aactgacgga gcaattttgg ctcgatacac gtattccctt atcaaacgac
     6841 ttggatgact ggagaaagct atctaacaaa gagaaagact tggtcggaaa agtttttggt
     6901 ggtttaaccc ttcttgacac tatgcaatct gaaactgggg ttcaagccct tcgcgcagac
     6961 atccgtacac cacatgagga agctgttttc aataacatcc aatttatgga atctgtccac
     7021 gctaaatctt actcatcaat cttttctacc ttgaatacta aggctgagat tgaagaaatt
     7081 ttcgaatgga ccaataccaa tccttaccta caaaagaagg ctgagattgt caacgaaatc
     7141 tacctaaacg gcagcccact tgaaaagaaa gttgccagcg tcttcctcga aaccttcctc
     7201 ttctactctg gtttcttcac tcccctctac tatctcggta acaacaaact agccaacgtt
     7261 gcagaaatca ttaaattgat tattcgtgac gagtctgttc acggaaccta cattggttac
     7321 aaattccaac ttggtttcaa tgaattgcct gaagaagagc aagaaaaact caaagaatgg
     7381 atgtacgacc tactctatac tctttatgaa aatgaagaag gctacacaga gagtctttat
     7441 gacggtgttg gttggactga agaggttaaa accttccttc gctacaatgc caataaagct
     7501 ctcatgaaca tgggacaaga tccacttttc ccagattcag ctgaagatgt caacccaatc
     7561 gttatgaacg gtatttcaac aggaacttcc aaccatgact tcttctctca agtcggaaat
     7621 ggttaccttc ttggcgaagt tgaagccatg caagatgatg actacaacta cggtttggac
     7681 taatactctt cgaaaatcaa attcaaacca cgtcagcttc gccttgccgt actcaagtac
     7741 agcctgcggc tagcttccta gtttgctctt tgattttcat tgagtataat tctccaccac
     7801 tcttaaccat caaaaagtaa actagaaaca acaaaataat aacccaacaa aaatatcgaa
     7861 agttttgaaa acaaacttcg atatttttgt ttttgtttca ttttgttgtt tttgtatttg
     7921 aatgatgagt ttgtttatgg taagatagta gtaggaaacg aggtgataat atgctcaaac
     7981 aagaaaaatt aaccaaaatt ttagagatag taaatagtaa aggaaccata acagttaaac
     8041 agattatgga cgaaatagcc gtttcagata tgactgcaag gcgctattta caggaattag
     8101 ctgataaaga tttgctgatt cgtgtgcatg gtggagctga aaaacttcga accaactccc
     8161 ttttgactaa tgagcgatca aatattgaaa aacaagccct ccaaacggca gaaaaacaag
     8221 aaatagccca ttttgcaggc agtctagtag aagaaagaga aactattttc attggaccag
     8281 gaacaacatt agagtttttt gcgcgtgagt tgcctattga caatatccgc gtcgtaacca
     8341 acagtctacc tgtttttctg attttaagcg aacgaaaatt aacagatttg attttgatag
     8401 gtggaaatta tcgcgatatt acaggtgctt ttgttggcac attgacccta caaaatctct
     8461 ctaatctcca attttctaaa gctttcgtta gctgtaatgg tattcaaaac ggagctctag
     8521 ctacttttag cgaggaagag ggagaggctc aacgcatcgc tttaaataat tctaataaaa
     8581 aatatttact cgcagatcat agtaagttca ataagtttga tttttatact ttttataata
     8641 tatcaaatct tgatactatt gtttcagatt ctaaactaag tgattcaatc ctttttaagc
     8701 tatctaaaca cattaaagtc atcaagcctt aataaactga aagagcctgg gtaacaactc
     8761 aatttcagaa gaaaaaaagt aaatcttccc acaataaaac gcatagtatc aggtgtttca
     8821 acacctgata ctatgcgttt ttctattctt caggattgat aaaatttaaa aatagatttt
     8881 taaattcttc cagatcatca tctgaatgac aaatccattc tttaccagtc gagacatacc
     8941 attttccaag acttttcaat tcttcactcg tcaaacacgg tatttgagag catttttcga
     9001 aatttataat ataaactttt tcataaatag attggataaa atctttgaac atctttttga
     9061 ctcactaaaa ttctatatct aatgactaat tctactagtc tataatctga gtttccgcta
     9121 ctttcttgta ccagtgagct gatttcttag gataacgttc ttgagtttca aaatctacgt
     9181 agaagagacc ataacgtttc tcataaccgt ttgaccatga gaagacatcc attaatgacc
     9241 aaatgaagta accttttaca ttagctccat ctgcaatcgc atcagataaa acctccaagt
     9301 gttgcttcac gtaatcaata cgtccatcat cgtaaacagt gttatcaacg aactcatctt
     9361 tatatccaag accattttca gtgatgtaga ttttcttata gttaggataa tctttcttca
     9421 cgcgcatgat ttggtcatac aaaccttgag ggtagataat ccaatcccaa tccgtgcgtg
     9481 gtacatagtc aggagctaca cgacgaccaa tacctttgat ttggtattta gagcttcctt
     9541 tttcaccttt accattatgg ataatttcag tttctccatc aaaggcttcc atccagtcac
     9601 tcatatagta gttgattcct aggaaatcat tcaagtcttt tgcagcttct aatgctgtaa
     9661 aatcttcttc acgaagatcc aagctaccac cattggcagc caagatagcc tctacccctg
     9721 ccagagtctt ttcagagtag tgacccagat aggttgcatc caaaataaat ttgttgtgaa
     9781 taatatcttc caactcagct gcacgaacat ctgctggatt ttcatgatct agaggatatt
     9841 tagtaggcag ggcgtgaaca acaccaattt cccctttata gcctttctct ttgtacaatt
     9901 ttaccgcgcg tgcatgagac accatcatat tgtggtgtga ttgaaagact ttggcaaggt
     9961 cgtactggat acctggaggg aatttcccaa ccaaatattg accatcaccg attggtccaa
    10021 tttcattaaa ggttgtccaa tagtttactt ctggaaattc ttcaaaacag aaagcagcgt
    10081 agtctacaaa atgttcgata ttttcacggt ttaagaagtc tccatttgag tggagagctt
    10141 ctggcgtgtc aaagtgatga agagttacaa aaggctcaac atgacgtttg tgacactctg
    10201 caaataaatt atgataaaac tcaacacctt taacatttac ttggccgtaa ccagtcggga
    10261 aaatacgtga ccaagcaata gaaattcgaa taccattgac accatactct tctgctagct
    10321 tgaggtcaac tggatatcga ttgtaaaaat cactagctgg ttcggcagtg taccagtagt
    10381 tatcctcaag atatttatcc caagcaactg gtccttttcc atcagtatgt gtagcacctt
    10441 ctgcttgata agcagctgtt gcgccaccga aaataaagtc ttttggaagt gtttttgtca
    10501 tttttttcac ctatttcttg atttaaataa agtaaaagtg agaggagagg agtcagtgag
    10561 ccatgcttct ccatctcact tcttgtacca agtcactgaa ttgtgacatg aggaggtaaa
    10621 aacgatatct ttttaccgac gaattaataa ggcgattagg aaattcgcca tagcgatttc
    10681 cgtaacgatg ggagactgtt tcacagttcc tagccttaat cgaattgctc ttgtacgaat
    10741 gctagggcac cttttccatc acgagttaat ttgatgtatt gagcgccttc tgtcttagca
    10801 agtttaatac cgagcttatc tgtttctgcc ttcatatctt caaagtttga agcaacttga
    10861 ggggcaagga taactagatt aaactctggt aacatttcac ggtgagcacc atagccgcct
    10921 gctgctgctt tcacagggac attgtattct gctgctgcct tattcaaagc atttgcaagg
    10981 agtccacttg tacctccacc agcacagaga acgaggacat ttgtttcttc agtgatggta
    11041 ttttgtgctg catcgacacc cgctttttca agaatagcat ccgcttttgc agtgttgaag
    11101 tttgcagcaa ctttttcttt caattcagat gaagagtttc ctttccgttc ttcttctaaa
    11161 atttgatggt cataaacttt aacaaatgga taatagatta aagtgtcgat aatgattaaa
    11221 gttatagcca agacgaatga caatggagcc agcgccgttc ccataacaat accaattgga
    11281 gcaggtgttg tccaaggtaa aataatactg aaactattca tttgtagaac atctacaaaa
    11341 aatttcataa tccaaacatt gataatagga gcagtaacaa acggaataaa gaagatagga
    11401 tttaaaacaa ttggagcacc aaataggatt ggttcattta cgccaaagaa agtaggaact
    11461 acagacgcac gtccgacaat tctatttctt tttgatttac ataaccacat aaacataaat
    11521 ggaactacta gtgttgcacc agtaccaccc attgttacaa caaaagtttg agtaactgga
    11581 tttaaaattt tatctgcgtg cataccagct tgcacaagct gaacattagc ttctatattt
    11641 gcataactga tagctacaat taaaggttct acaacagatg gcccatgaat tccaacaaac
    11701 caaaagaaag cataagcacc aaatacaata gctaaaccga tataaccatc agtagctgaa
    11761 aatagagggg ctaatatttt accaacagat tctgctacat ttgtaccaaa aatatttcta
    11821 acaattaaat ccaatccata tattgaaaga acagataagg caaacggaat aacatcttta
    11881 aaaacttgtg caatatttgg tggaacctct tcaggaagtc taatggttac attattttta
    11941 atacatactt tatagatatt tactgtaata aaagctgcca aaaatgcagt aagtaatcct
    12001 ctagtaccta aaagaccatt agcaaatcca ccttcaattg gatcagctgc cagtattaac
    12061 aatccaacaa cagctgctaa aaaagttgac atgtagttga tttggttggt tttctccata
    12121 ctacgtgtat taactgaatc tgttaacgat tttgcagttg tcccagctac taagagagct
    12181 aaaatcccca ttgagtagtt gtaaggtttc aaaataaaag ctaactgttc atcagaccat
    12241 ttaaacccaa aaatattggg cacagcagct attagtataa aaatacttga gaataatact
    12301 gctggcatac tggaaataaa accatctttt atcgctctta agtatatatt tctcgataat
    12361 ttctcaaaga aaggctttcc tttctcaata aaaattatta acttatccat tttatttaac
    12421 tcctctcttg taaagttcaa ttaaatggtg cattaggtct tttaacaaga tagttgtcat
    12481 caagtgatct tgaccatgca tcatggtcac actatacgct aagtcctcac cagaagcttc
    12541 cttagtcaat agacttgttt gcgcgtggtg agcctctgca atacagctac cagcttcctc
    12601 taccagagcg tccgcttttt caaaatcacc agcttcagca gccttcaagg cttccaatag
    12661 ttttgaacga gcatcgccag cataggctac gatttcaaaa cctaacaatg ttacttcttc
    12721 tctattcatg atagaattct ccttatatag ttttaaataa atttttatga caataaacgt
    12781 tggatatgta gaactagata aactcgttca cttttataca aatcaagacc cgtatgttgc
    12841 gtaatcacat catagatctt ggaaccaatc tcgaaggctt ttggatagga ttgtttaata
    12901 tgatcttcca tatccagaag tgattggtta tcatctctag atctgtctaa ataatccaag
    12961 aaataattca aatggatcat aaagcgatca tagaaatggt tattcttttt agttcgttga
    13021 attgcatagt ccgttaaaac ttcttcaaca ttcctgagaa tttctttcct cttatcaatc
    13081 gactccacaa gttccacttc attttcacct tcagcattaa tgaaatgata agcaatccga
    13141 ataatttcgt cctcaggaaa atgatctgct agcttctgac agtaaatttc aaaagcttca
    13201 tttgcgattt gaaaagcgac aggatactta gcagaaatat ctggcagatt actatccttg
    13261 taccttcctt gagttagagc ttgataagaa cagtaaatat gatctgtcaa ggttacatag
    13321 agatactctt gaatcggata atgatatttc tttgatagct tatcaatgat ttcataggtc
    13381 actgtgataa aatcaagcgg aacatctttg agaagagcca taaagttttc tctggactct
    13441 tcggtcttca tccgaaagat tttctcaaca tgattttcag caatcaaatc ccccttcttc
    13501 tttccgaatg caatcccctt accaattaca atcacctctt ctcccttatc atttctgaca
    13561 agcgagacat tgtgattcat tggatttaga attcgataca tgtcaacctc cttttatatc
    13621 ttaaaggtat atgagtacaa aaaatgacca caaatgaact agaaaatcag ctgatttcta
    13681 attcacctgt gatcatgcct aatattactt agtaacactc accttgtatt aacttgtgat
    13741 ttaagtatag cacaagtaag ttattttgta aacctttaca tacaactttt tttaaatttt
    13801 tttagattca tgttcctaaa ctaggaggac tttcttacac acgttctttc catgaagttg
    13861 ctgttgtttg aagaactttg ttgagctcat caatgttttc aaatccagtt gtgcgaagcc
    13921 attcgcgagc tgctgtttca ccatctttga tgtatgcttc aactgatcca gcccatgttg
    13981 cacggccaca aagaactccg ttaaagtttg cacctgattc atgagcaaat acaagagtat
    14041 cttggaagag tttagctgat acaccagcac tcaagtagat gtatggcaag ttcgttgctt
    14101 catcttgcgc tttgaagaag gctgctgctt cttcacgtgt ataaactact tcaccttcag
    14161 cgaagccttc aacatattta atgttaacag gaacttcaac tttcaagaca tcaatgttaa
    14221 agcgtgggtc tgaaaagact ttcatagcgc cgataacttt gtgtggtttt actttcgcgt
    14281 attctacaga acctgcatcc gcaatttttt catcgtaagc aagaatttca aggaagaatg
    14341 ggatatcttc agccacacac tcagaaccga tgcgttcgat gtaggcttgt ttttcttgat
    14401 tgagttcgtc tgagctatct acatcatagt aaagcaagaa tttaactgca tctgcacctt
    14461 cttctttaat acgttttgca gaccagacat ccaagcagtc tggcaagcgt tttgtgcttg
    14521 ttgtgtcata acctgttttt tcataagcaa ggagaagacc agctttttca tcaagagctt
    14581 tagttgctgg aagtccatac tcagggtcaa gaagcataga tgaagcgtat ttagtcaatt
    14641 catctgctac caagacttta agttcttcca tttgggccac agttggttct tctgtttggt
    14701 gttgagccat gaggcgtttc aaagcaccac gttggtcaaa tgcaagagct gagatgatac
    14761 cattttcatc agaaagtttt tctaagcgta cacgtttttg ttctgttaaa gccattttat
    14821 acctctttta ctattaattg atcatataga gcttgatagt tggccatgtt gacatgacca
    14881 gtcatttttt cttgagtatt gagcatacca aggacatttg ccttgatgag taattctgca
    14941 tccgattctt tgtgaagaag tcctgaagaa attcctgcca cagtagagtc tccagatcca
    15001 acaggattta ccacctgaat tctaggaata tctaccttgt agaaagtgtc accatgtttg
    15061 gcaaaagtac cgttggcacc aagtgaaacg ataatccatt caatccctgc aaacaaaggt
    15121 tcttgaagta cttcttttaa ttcatccaaa tcctcagaaa cttctcttcc aagaagctga
    15181 gacaattctt cattatttgg tttgatgact gttggtttat ggggtgattc aagaacagcc
    15241 tgaagtgctg cacctgagca gtccaagact acaggcttgc cagcttgatt agcaagttct
    15301 accaagctcg catagtaatc aactggaagg ccagctggca gactacctga gatggccact
    15361 acttcaactg actccaagag ttttttgaaa tgttccaaaa agtcttgacc ttcctgttcc
    15421 aatacttcag gacctttttc aagaacttct gtttggttgt ctccgtggag aatagcgata
    15481 cagttacgag tttctccctg aattgagaag aaatctttct ttacttgatt atcgatatgt
    15541 tcaaccaaaa actcaccaag tttgccaccc actaaaccag tagcaagaac agaatcgcca
    15601 aattctgaaa gtactcgggt aacattgagt cccttaccac cagccgtttt ggttacatcc
    15661 accacacgat tgacagtatc aatcttcaac tcatccaagg gataggaaat atcaatggat
    15721 gggttcattg tgactgttaa aatcataggt cacctcttag tcgtggtatt ctccgcgatc
    15781 ccatttttca aggaattctg taaagaagtt tgcgtctgtt tgttgagcat tgtgactttc
    15841 aaggtgttca attttcgcaa tcaatttctt gttttcttca gatggtttgt attcagcatg
    15901 aatgaaagct tcgatgatat cacacataag caattcacca gtaatcttac caccaaagcc
    15961 gataacgtta gcgttcaatt gttctttagc ataaagggct gttgtcatat cacgaaccaa
    16021 ggcagaacga acacctggaa ctttatttac agcgttgttg ataccaacac cagtaccaca
    16081 gatacatacc ccaagatcag cttggccgct agttacagct tcccctactt ttttaccaaa
    16141 gattgggtag tgagtccgtg tatggtcata tgtaccaaag tcaatgactt catatccttt
    16201 tgatttcaaa aattctgaaa ccgccatttt ttcatctgtt acgatgtggt cgcatccaat
    16261 tgcaattctc atttttaact tacctttctt actgtaatct aattagccca ttttgttcaa
    16321 catgtcgacc cggatttgat gacgtccacc atcgtattta ccgttaacaa atcctttagc
    16381 gatgttttta gccaattcat caccaacaag ttgtgcaccc atagtgatca tacgtgagtt
    16441 gttgtggcca cgagtcatat aagctgaacg ttcgtcagat acttctgcag caaccattcc
    16501 tttgatctta gttgcaacca taaatgaacc agctccataa gcatcaatca cgataccaag
    16561 gttttgttct tctttgttta cttctgcagc aacagcgaga gtcacatcaa caaagtcttg
    16621 accttcagct gtaacatcca caaggtggaa gttttctttt tctaagaagt ctttcacaac
    16681 ttctttcaat ctcaaacctg cagcatctgc accgataaca atagacatat tgtatactcc
    16741 tttttatttt ttctatgctg gattccagca gtgtattggc tgtctttaaa aaacagtcaa
    16801 ttagtcctca caaacataat atactactat tgtttgaaga agtcaacagt ttgtgtttgt
    16861 ttttgttatt tattttttac tttttttata aaacttctat ctcaaaccct aattcttcaa
    16921 cctgattggc ttctaagaga caaacattct tcttatcttc taaatgatct ccttcttcaa
    16981 ggaatgttga caagccagac catggttcaa aggtaatgaa aggtcccttg ttcaaagttg
    17041 accagatgat gaggtttgga aattctgcaa aatgcacttt caatccctta tcatgtttaa
    17101 gagaacgaag ggcaattgtt cgagattgca attcatccaa agtcactgca tctgtgctga
    17161 aaagatcata actaagatct atttcttttt gtccctctag ccatggactt ctatcttgga
    17221 aatccaacat acctgtttct gggaaaggac gtggaacaga gcaaatctct tctttctcaa
    17281 actctagata ataatcttca tagacttcat catcaagtag aagacaatta aatcctggat
    17341 gtccaccaat aaagtaaggc ctgaccttgc tagtttcttt a
//
LOCUS       DAVHTH010000041        17264 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.041, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000041 DAVHTH010000000
VERSION     DAVHTH010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17264)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17264)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17264
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.041"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            650..1339
                     /locus_tag="VVR63_001484"
     CDS             650..1339
                     /locus_tag="VVR63_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEU6129493.1"
                     /translation="METKKIKNLKGQIIVSCQALEGEPLYTPNGGVMPLLAKAAFQAG
                     AKGIRANSVRDISEIKEEVDLPIIGIIKRDYDGFEPFISATMKEIDELVSEGVDILAL
                     DCTNRSRPGYDNITDFIHDIKVKYPNQLLMADISTFEEGKVAAESGVDFVGTTLSGYT
                     PYSPKKDNPDFELVERLVKELDVPVIAEGRISTPEQARKMLDLGAYAVVVGGAITRPK
                     EIAQRFINVIK"
     gene            1364..2281
                     /locus_tag="VVR63_001485"
     CDS             1364..2281
                     /locus_tag="VVR63_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate lyase"
                     /protein_id="HEU6129494.1"
                     /translation="MKDLTKYKGVIPAFYACYDENGEISQERVKSLVQYFIDKGVKGI
                     YVNGSSGECIYQSVEDRKQIIEAVMEVAKGKLTVINHVACNNTKDSIELAKHSESVGV
                     DAIAAIPPIYFKLPEYSIAAYWNAMSEAAPNTDFIIYNIPQLAGVALTGSLYATMRQN
                     PRVIGVKNSSMPVQDIQMFVAAGGEDYIVFNGPDEQYLGGRLMGAEAGIGGTYGVMPD
                     LFLKLESLIQERDLDTAKKLQYAINEVIYKMISGKANMYAVAKEVLRLNEKLDLGSVR
                     QPLEALAEGDLEVAKQAAELIQQARKEFL"
     gene            2309..3850
                     /locus_tag="VVR63_001486"
     CDS             2309..3850
                     /locus_tag="VVR63_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000537364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter"
                     /protein_id="HEU6129495.1"
                     /translation="MGTTGFTIIDLIILIVYLLAVLVAGIYFSKKEMKGKEFFKGDGS
                     VPWYVTSVSIFATMLSPISFLGLAGNSYAGSWILWFAQLGMVVAIPLTIRFILPIFAR
                     IDIDTAYDYLDKRFNSKALRIISALLFIIYQLGRMSIIMYLPSAGLSVLTGIDINILI
                     ILMGAIAIVYSYTGGLKSVLWTDFIQGVVLISGVVVALFVLMANIKGGFGAVAETLAN
                     GKFLAANEKLFDPNLLSNSIFLIVMGSGFTILSSYASSQDLVQRFTTTQNIKKLNKML
                     FTNGVLSLAIATVFYLIGTGLYVFYQVQNAGSAASNIPQDQIFMYFIAYQLPVGVTGL
                     ILAAIYAAAQSTVSTGLNSVATSWTLDIQDVISKNMSEDRRTKIAQFVSLAVGLFSIV
                     VSIIMAHSDIKSAYEWFNSFMGLVLGLLGGVFILGFVSKKANKQGAYAALIVSTIVMV
                     FIKYFLPPTAVSYWAYSLISISVSVVSGYIVSVLTENKVSAPKYTTIHDILEIKADSS
                     WEVRH"
     gene            3876..4334
                     /locus_tag="VVR63_001487"
     CDS             3876..4334
                     /locus_tag="VVR63_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEU6129496.1"
                     /translation="MIISEQSDFRRYASVNKHFSKVCDFLENTNLTDLVDGKIDIDGE
                     NVFANCMTYLADGVPGDIFETHKKYLDIHIVVENTEKMAVTSPVRAQSRVPFSEEKDI
                     AFYDSKDYQIVELLPGNMLVTFEEDLHQPKIHCNDETVKKLVIKVLNEEK"
     gene            4336..6558
                     /locus_tag="VVR63_001488"
     CDS             4336..6558
                     /locus_tag="VVR63_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exo-alpha-sialidase"
                     /protein_id="HEU6129497.1"
                     /translation="MKKNIKQYVTLGTVVVLSAFVANSVAAQETETSEVSTPELVQPV
                     APTTSISEVQHKSGNSSEVTVQPRTVETTVKDPSSTAEETPVLEKNNVTLTGGGENVT
                     NELKDKFTSGDFTVVIKYNQSSEKGLQALFGISNSKPGQQNSYVDVFLRDNGELGMEA
                     RDTSSNKNHLVTRPASVWGKYKQEAVTNTVAVVADSVKKTYSLYANGTKVVEKKVDNF
                     LNIKDIKGIDYYMLGGVKRAGKTAFGFNGTLENIKFFNSALDEETVKKMTTNAVTGHL
                     IYTANDTTGSNYFRIPVLYTFSNGRVFSSIDARYGGTHDFLNKINIATSYSDDNGKTW
                     TKPKLTLAFDDFAPAPLEWPRDVGGRDLQISGGATYIDSVIVEKNNKQVLMFADVMPA
                     GVSFREATRKDSGYKQIDGNYYLKLKKQGDTDYNYTIREHGTVYDDRTNRPTEFSVDK
                     NFGIKQNGNYLTVEQYSVSFENNKKTEYRNGTQVHMNIFYKDALFKVVPTNYIAYISS
                     NDHGESWSAPTLLPPIMGLNRNAPYLGPGRGIIESSTGRILIPSYTGKESAFIYSDDN
                     GASWKVKVVPLPSSWSAEAQFVELSPGVIQAYMRTNNGKIAYLTSKDAGTTWSAPEYL
                     KFVSNPSYGTQLSIINYSQLIDGKKAVILSTPNSTNGRKHGQISIGLINDDNTIDWRY
                     HHDVDYSNYGYSYSTLTELPNHEIGLMFEKFDSWSRNELHMKNVVPYITFKIEDLKKN
                     "
     gene            6598..7707
                     /locus_tag="VVR63_001489"
     CDS             6598..7707
                     /locus_tag="VVR63_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEU6129498.1"
                     /translation="MVNYGIVGAGYFGADLARSMNKIEDAKVVAVFDPNHGEEVAQEL
                     GSDVCASLDELVAREDIDCVIVASPSYLHREPVVKAAQHGKHVFCEKPIALSYEDCKA
                     MVDACKENNVIFMAGHIMNFFNGVHHAKELITQGKIGKVLYCHAARTGWEEQQPTVSW
                     KKLRSQSGGHLYHHIHELDCIQFIMGGLPEKATMVGGNVYHKGENFGDEDDMLIVNLE
                     YSDDRYAVLEYGNAFRWGEHYVLIQGTEGAIKLDLFNTGGTLRVKGEGESHFLVHETQ
                     EEDDDRTAIYTGRGMDGAIAYGKPGVRCPLWLQTCIDKEMEYLHDIIKGGEITEEYEK
                     LLNGVAALESIATADACTLSVKEDRKVSLSEITNA"
     gene            7864..8754
                     /locus_tag="VVR63_001490"
     CDS             7864..8754
                     /locus_tag="VVR63_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEU6129499.1"
                     /translation="MKIIGIDIGGTTIKADLYDDFGTSLNQFKEIETIIDYDLGTNQI
                     LNQVCDLIGEYVLNYSIDGVGISTAGVVNANTGEIIYAGYTIPGYIGVNFTSEIEKRF
                     GLSTFVENDVNCAALGELWEGQAKDKKNVVMVTIGTGIGGSIIVNGQIVNGFNYTAGE
                     VGYIPVGNSDWQSKASTTALIHLYQKKSLKTNQTGRTFFTDLSSGDKVAKETFEIFVE
                     NLTKGLLTISYLLNPEILILGGGILAKKDILLPEIQSSLAKNAMDNRFLPKNVVAATL
                     GNEAGRIGAVKNFLDRISNK"
     gene            8779..9102
                     /locus_tag="VVR63_001491"
     CDS             8779..9102
                     /locus_tag="VVR63_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6129500.1"
                     /translation="MTNSVFSTMQDIENVATDIIKSYDNEIYTYKAVSQEELEKLEKS
                     YDEKSHEELISIESNLEMKQQNLIDEVNKTIKENDAKIQYISSSRRGEFVEKIIGRVV
                     EKYGY"
     gene            9092..11083
                     /locus_tag="VVR63_001492"
     CDS             9092..11083
                     /locus_tag="VVR63_001492"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HEU6129501.1"
                     /translation="MAISQMKRISLLFTKSSLDDVLKTIQELESVQFRDLKVQDNWSE
                     ALEKDEVVFSTIQISHTSNSHHGVIEGNDALNYLMNKQQHLEATVEKLQEYLPKENTF
                     KLLQQPPITTSYEELEKFGKANVAEGVLKKVNHQINRVHELERNIQSNNEEIERLIKW
                     EKLEIIPAHLEQFSFCRGKVGTIPRTVDNRLYNNFLENNIEVQEIFSNDREYGVVVFY
                     QSSCSIDFDEYLFEPFDYSRKELPKQRVVDLDQENMQLITEKENIIASLQDSKKNLID
                     LQWQIDYILSIYARQISKNNLLSTPHLVALEGWIEETRILYFIKVMDERFGHSIYIYE
                     SETLSDNQDEIPIKLTNHSLIEPFELLTEMYALPKYYEKDPTPVLAPFYFTFFGMMVA
                     DLGYGLLLFLGIMLALKIFHLPSVTKKFLKFFNILGVAVAIWGGIYGSFFGYELPFHL
                     ITTTSDVMTILVVSVVFGFITVFVGLLASGLQKVRMKKYAEAYNSGFAWCVILLGLLF
                     IAVGMLMPDIRPLFVLGKWVSIFNAVGILIASIIQAKSLSGIGSGLFNLYNISSYIGD
                     LVSFTRLMALGLSGASIASAFNLIVGLFPGTLAKLTIGLVLFILLHAINIFLSLLSGY
                     VHGARLIFVEFFGKFYEGGGKPFQPLKASEKYIKVITKN"
     gene            11099..11575
                     /locus_tag="VVR63_001493"
     CDS             11099..11575
                     /locus_tag="VVR63_001493"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HEU6129502.1"
                     /translation="MEHLATYFSTYGGAFFAALGIVLAVGLSGMGSAYGVGKAGQSAA
                     ALLKEQPEKFASALILQLLPGTQGLYGFVIGILIWLQLTPELPLEKGVAYFFVALPIA
                     IVGYFSAKHQGNVAVAGMQILAKRPKEFMKGAILAAMVETYAILAFVVSFILTLRV"
     gene            11609..12190
                     /locus_tag="VVR63_001494"
     CDS             11609..12190
                     /locus_tag="VVR63_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000067169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6129503.1"
                     /translation="MSNLENLRESVIEQAHEKGSMKLLDSKKKIDDEFEMQKSVIVKK
                     KEAEHERKLKELQQKYQIIFQQLKNKERQSTLVSKQKILKELFQSALIEMESWSADKE
                     MEFIYRILERYSQQEVIVTFGERTLAKFNLEQLEKLKFSFPNHLFSEQPISNESGLLI
                     SIGKIDDNYLYKTLIGSISKEESSSIANQIFIN"
     gene            12255..13262
                     /locus_tag="VVR63_001495"
     CDS             12255..13262
                     /locus_tag="VVR63_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HEU6129504.1"
                     /translation="MDTNLFSKINTTISVKENDFITEEKFQKIIQSKDTETLAFILEA
                     TPYHLSIDVLENPSQTEISLMTKLVNDYRWAYAESPSDKIVTLFALRYVYHNIKVLLK
                     SKAAIKKDFSKLLIPIGIFDIESLKHLVSSLHSDTLPDFMVHEVESIWNEYETFNNIR
                     VLDVGADLAYFKHLKLLSNELGEVLSQVIVAMIDFYNIITVKRGLSQNKSHGDILQLL
                     SDEGSISAKEFIYIVENQEIFVWFNKINPSLDSIFSTYELKMQDATISSSELEFLCDL
                     LLYKTLDQGRYNVDGPLVLARYLLGCEFEVKNLRMIISALQNTIPFESIKERIRPHYG
                     S"
     gene            13252..13572
                     /locus_tag="VVR63_001496"
     CDS             13252..13572
                     /locus_tag="VVR63_001496"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HEU6129505.1"
                     /translation="MEANKYKIGIIGSHDIILPFSMIGFDIFSAYQEQEAINTLRKLA
                     QSDYGVIYITEDIASMILDTIRHYDSQVVPAIILLPTHKQGLNLGLKRIEDNVEKAVG
                     HNIL"
     gene            13635..15410
                     /locus_tag="VVR63_001497"
     CDS             13635..15410
                     /locus_tag="VVR63_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HEU6129506.1"
                     /translation="MTQGKIIKVSGPLVIASGMQEANIQDICRVGKLGLIGEIIEMRR
                     DQASIQVYEETSGLGPGEPVVTTGEPLSVELGPGLISQMFDGIQRPLDRFKLATHNDF
                     LVRGVEVPSLDRDIKWHFDSTIAIGQKVSTGDILGTVKETEVVNHKIMVPYGVSGEVV
                     SIASGDFTIDEVVYEIKKLDGSFYKGTLMQKWPVRKARPVSKRLIPEEPLITGQRVID
                     AFFPVTKGGAAAVPGPFGAGKTVVQHQVAKFANVDIVIYVGCGERGNEMTDVLNEFPE
                     LIDPNTGQSIMQRTVLIANTSNMPVAAREASIYTGITMAEYFRDMGYSVAIMADSTSR
                     WAEALREMSGRLEEMPGDEGYPAYLGSRIAEYYERAGRSQVLGLPEREGTITAIGAVS
                     PPGGDISEPVTQNTLRIVKVFWGLDAPLAQRRHFPAINWLTSYSLYKDSVGTYIDGKE
                     KTDWNSKITRAMNYLQRESSLEEIVRLVGIDSLSDNERLTMEIAKQIREDYLQQNAFD
                     SVDTFTSFAKQEAMLSNILTFADQANHALELGSYFTEIMEGTVAVRDRMARSKYVSED
                     RLDEIKIISNEITHQIHLILETGGL"
     gene            15411..16796
                     /locus_tag="VVR63_001498"
     CDS             15411..16796
                     /locus_tag="VVR63_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000111247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HEU6129507.1"
                     /translation="MSVIKEYRTASEVVGPLMIVEQVNNVSYNELVEIQLHNGEIRRG
                     QVLEIHEDKAMVQLFEGSSGINLEKSKIRFAGHALELAVSEDMVGRIFNGMGKPIDGG
                     PDLIPEKYLDIDGQAINPVSRDYPDEFIQTGISSIDHLNTLVRGQKLPVFSGSGLPHN
                     ELAAQIARQATVLNSDENFAVVFAAMGITFEEAEFFMEELRKTGAIDRSVLFMNLAND
                     PAIERIATPRIALTAAEYLAFEKDMHVLVIMTDMTNYCEALREVSAARREVPGRRGYP
                     GYLYTNLSTLYERAGRLVGKKGSVTQIPILTMPEDDITHPIPDLTGYITEGQIILSHE
                     LYNQGYRPPINVLPSLSRLKDKGSGEGKTRGDHAPTMNQLFAAYAQGKKVEELAVVLG
                     ESALSDVDKLYVRFTKRFEEEYINQGFYKNRNIEDTLNLGWELLSILPRTELKRIKDD
                     LLDKYLPLVEV"
     gene            16819..>17264
                     /locus_tag="VVR63_001499"
     CDS             16819..>17264
                     /locus_tag="VVR63_001499"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000251933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HEU6129508.1"
                     /translation="MVRLNVKPTRMELNNLKERLTTAERGHKLLKDKRDELMRRFISL
                     IRENNQLRKEVESYLIDNLKSFAVAKSLKNSQMVEELFSIPSKEIELFVEKENIMSVT
                     VPRMHMNITSQNENSEYSYLSSNSEMDDVFATMNSLIYKLLRLAEV"
BASE COUNT         5803 a         2442 c         3444 g         5575 t
ORIGIN      
        1 cctttttgct aaagttttaa aaataaacaa taattaagat tatagtgcgt tgaatctata
       61 ttaggacata acaattctta aatcattgtt agaaattagt ttgaattttc caatcaattt
      121 gttcgatttt tacatcattg cattatatca tgtgactatt aaccttgttt tctcctaaaa
      181 ttgattttct tcttttctta tcttgtccac tcgaaacaag tattgtaaga atttgattat
      241 ttttgaaagt acttttaata tatttgagat agttaaaaaa gatttgaaac taaattccaa
      301 attagaaaaa gacttgaaat gctaaaaaaa aaaagtatac tctaattgaa aacggtaaca
      361 aaactaattt agagaatgaa atatagagta tttctctctt aaaagttttt ggtgaaacga
      421 gatgtagaaa ggagatttag ccaaagagtc tattagtgct agaataatag attagaatta
      481 tagtgtattg aatctataac agtacgcctt aaatgctaaa atatttctat aaattaattt
      541 aactttcctg atagggctgt tcatatctta tttcaattca ctatataaat aaaattgtag
      601 tagatgttat tgaattagta aaaaaaataa aaaaacggag gttttctgaa tggaaactaa
      661 aaaaattaaa aatttaaaag gtcaaataat tgtttcctgc caagcgttag aaggagagcc
      721 actttatact ccaaatggag gagtgatgcc gttattagca aaagccgcct ttcaagcagg
      781 cgctaaaggt attcgtgcta attctgtccg cgatatttca gaaataaaag aagaagttga
      841 cttaccaatt ataggtatca taaaaagaga ttacgatggc tttgaacctt ttatttcagc
      901 aactatgaaa gagattgatg aattagttag tgaaggagta gacattttag ctttggattg
      961 tactaatcgt tcaagaccag gttatgataa tattactgac tttattcatg atattaaagt
     1021 caagtatcca aaccaattat taatggctga tatttctact tttgaagaag ggaaagtagc
     1081 tgctgaatcg ggagtagatt ttgtgggtac gacattatct ggttatacac catatagccc
     1141 taaaaaagat aatcctgatt ttgagttagt tgaaagattg gtaaaagagc ttgacgtacc
     1201 agttattgct gaaggaagaa taagtactcc ggaacaagct agaaaaatgt tagatttagg
     1261 tgcttacgca gtggttgttg gaggagctat cactcgtcca aaagaaattg ctcagcgatt
     1321 tattaatgtc atcaaataaa aaacaatata aaggagaaat ctgatgaaag atttaactaa
     1381 atacaaaggc gttattcctg cattttatgc ttgctatgat gaaaatggtg aaattagcca
     1441 agaacgtgta aaatctctgg tgcaatattt cattgacaaa ggtgtaaaag gtatctatgt
     1501 aaatggttct tcaggtgaat gtatttacca aagtgtagaa gatcgtaaac aaattattga
     1561 agctgttatg gaagttgcta aaggtaaatt aacagttatc aaccatgttg catgtaataa
     1621 cacgaaagat agtattgaat tggcaaaaca ttcagaaagt gttggagtcg atgctattgc
     1681 tgctatccca cctatttact tcaaattgcc agaatattca attgcagcat attggaatgc
     1741 aatgagtgaa gctgcgccaa atacagattt tatcatttat aatattccac aattggcagg
     1801 ggttgcgttg actggtagtt tgtatgcaac aatgcgtcaa aatcctcgtg tgattggagt
     1861 taaaaattct tctatgcctg tacaagatat tcaaatgttt gtagctgcag gtggagaaga
     1921 ttacattgta ttcaatggtc cagatgaaca atatcttggt ggtcgcttga tgggagcaga
     1981 agctggtatt ggtggtactt atggcgttat gccagatttg ttcttgaaat tggaaagttt
     2041 gattcaagaa cgagatttag atactgctaa aaaacttcaa tatgctatca atgaagttat
     2101 ctataagatg atatcaggta aggcaaatat gtatgctgta gcaaaagagg ttttgcgtct
     2161 aaatgaaaaa cttgatttag gttctgttcg tcaaccctta gaagcattgg cagaaggtga
     2221 cttggaagtt gcaaaacaag cagcagaact tattcaacaa gcacgaaaag aatttttata
     2281 ataaataaaa tcaatatgga gatatgttat gggcacaaca ggatttacaa taattgactt
     2341 aattatcttg attgtttatt tacttgcggt gttggttgca ggtatctatt tctctaaaaa
     2401 agagatgaaa ggaaaagagt tctttaaagg agatggttcg gttccttggt atgttacttc
     2461 ggtatccatt tttgccacaa tgctcagtcc gatttccttc ttgggactcg ctggtaactc
     2521 ttatgcaggt agctggattt tatggtttgc tcaattaggg atggttgtag ctattccact
     2581 gacaattcgt tttatcttac ctatctttgc acggatagac atcgatacgg catatgatta
     2641 cttggataaa cgttttaatt ctaaagcact tcgtattatt tcagcactct tgtttattat
     2701 ttatcaattg ggacgtatgt ctatcattat gtacctccca tcagctggtt tatcagtatt
     2761 gacaggaatt gacatcaata ttttgattat tttgatgggt gcaattgcaa ttgtttattc
     2821 ttatactggt ggtctaaaat ccgtattatg gacagacttt attcaaggtg tggttctgat
     2881 tagtggtgtc gttgtagctt tatttgtact gatggctaat attaaaggtg gctttggtgc
     2941 agtagcagaa acattagcaa acgggaaatt ccttgctgca aatgaaaaac ttttcgatcc
     3001 taacttgctt tcaaactcca tcttcttaat tgtgatgggt tcaggcttta caatcttgtc
     3061 ttcctatgct tcatctcaag atttggttca acgttttact acaacacaaa atattaagaa
     3121 acttaataaa atgttgttca caaatggtgt cttgtcactt gcaattgcaa cagtctttta
     3181 cttgatcggt acaggcttgt acgtattcta tcaagtacaa aatgcaggta gtgcagctag
     3241 caatatccct caagaccaaa tctttatgta ctttattgca taccagttac cagtaggtgt
     3301 cacaggtttg atcttggcag cgatttatgc agcagctcaa tcaactgttt caacaggttt
     3361 gaactctgtt gcaacttcat ggacattgga tattcaagat gtcatttcta aaaatatgtc
     3421 agaggatcgt cgtacgaaaa ttgcacaatt cgtatctcta gcagtaggtt tattctcaat
     3481 tgttgtttcc attatcatgg ctcattcaga tattaaatct gcatacgaat ggttcaatag
     3541 tttcatggga cttgtacttg gtctacttgg tggtgtattc attcttggtt ttgtttctaa
     3601 aaaagcaaat aaacaaggtg cttatgcagc gctgattgta tcaaccatcg ttatggtatt
     3661 tattaaatac ttccttcctc caacagctgt tagctactgg gcatattcat tgatttcaat
     3721 ttctgtatca gtagtttcag gttatattgt atctgttctt actgaaaata aagtatctgc
     3781 acctaaatat acaacgattc atgatatttt agaaattaaa gcggattcaa gttgggaagt
     3841 tcgtcactag tcactaatag aaaagagaaa ataatatgat tatttctgaa caatctgatt
     3901 ttagacgata tgcttctgtc aataaacatt tttcaaaagt ctgtgatttt ttagaaaata
     3961 caaatttgac agatttagtt gatggaaaaa ttgatattga cggggaaaat gtttttgcaa
     4021 attgtatgac ttatctagct gatggagttc caggagatat ttttgaaact cataagaaat
     4081 atttagatat tcatattgtt gttgaaaata cagaaaaaat ggcagtaact tccccagttc
     4141 gtgctcagtc acgtgtacct tttagcgaag agaaggatat tgctttttac gatagcaaag
     4201 actatcaaat tgttgaattg cttccaggga atatgttggt gacttttgaa gaagatcttc
     4261 accaaccaaa gattcattgc aatgatgaaa ctgttaaaaa acttgttatc aaagttttaa
     4321 acgaggaaaa ataaaatgaa aaaaaatatt aaacaatatg taaccttagg tactgtagtg
     4381 gtattatcag catttgttgc taactcagtt gcagctcagg agactgaaac ttctgaagta
     4441 tcaacaccag agttggtgca acctgttgca ccaacgactt cgatttcgga agtacaacat
     4501 aaatcgggta actcttcgga agttactgta caacctcgaa cagttgaaac tactgttaag
     4561 gatccatctt ctacagcgga agaaactcct gtcttagaaa aaaataatgt tactttaaca
     4621 gggggcggag aaaatgttac taatgagtta aaggataaat ttactagcgg tgactttact
     4681 gtagtgatta agtacaatca gtctagtgag aaaggtttac aagctctgtt tggaatatct
     4741 aattctaaac ccggtcaaca aaatagttat gtagatgtgt tccttagaga caatggtgaa
     4801 ttgggaatgg aagcgcgtga tacttcttcc aataaaaatc acctagtaac cagacctgct
     4861 tcagtttggg gtaagtacaa acaagaggcc gtgacgaaca ctgttgcagt agtagcagat
     4921 tcagtcaaaa aaacgtattc tttatatgca aatggtacaa aagtagtaga aaagaaagtg
     4981 gataacttcc taaacatcaa ggatattaaa ggtattgatt actatatgct tgggggagtg
     5041 aaacgtgcag gaaaaacggc gtttggtttt aacggaacac tagaaaatat caaattcttt
     5101 aatagtgcat tggatgaaga aactgttaaa aagatgacaa caaacgctgt tactggacat
     5161 ttaatttata cggctaatga tacaacaggt tctaactatt tccgtattcc agttctgtat
     5221 acttttagca atggtcgggt tttttcaagc attgacgctc gttacggtgg aactcatgat
     5281 ttcttgaata aaattaatat tgctacaagt tatagtgatg ataatggtaa gacatggact
     5341 aaaccaaaat taacattagc attcgatgat tttgcgccag caccattaga atggcctcgt
     5401 gatgttggtg gacgtgactt acaaatcagc ggtggtgcaa cctatattga ctctgttatt
     5461 gttgaaaaaa ataacaaaca agtactcatg tttgctgatg ttatgcctgc tggagtaagt
     5521 tttagagaag ctactagaaa agattcaggt tataaacaaa ttgatggtaa ttattacctt
     5581 aaattaaaga aacaaggtga tactgattat aattatacta ttcgtgagca tggtactgta
     5641 tacgacgatc gtaccaacag accaactgaa ttttcagtag ataaaaattt cggtattaaa
     5701 caaaatggta attatttgac ggtagagcaa tattcggttt catttgaaaa taataaaaag
     5761 actgaatatc gtaatgggac tcaagtccat atgaatatct tctacaaaga tgcattattc
     5821 aaagtagtgc caacgaacta tattgcatat atttctagca atgatcatgg cgaatcttgg
     5881 tctgcaccaa ctttattacc tcctataatg ggacttaatc ggaatgcgcc ttatttgggt
     5941 cctggacgtg gaatcattga aagctcaact ggacgtattc ttattccgtc ttacactggt
     6001 aaagagtctg cattcattta tagtgacgat aatggagcgt cttggaaagt taaagttgtg
     6061 ccacttcctt ctagttggtc agcagaagca caatttgtag aattgagtcc aggagtaatt
     6121 caagcataca tgcgtacaaa taatggtaaa attgcatatt taacaagtaa agatgcaggt
     6181 actacttgga gtgcgccgga atatttgaaa tttgtttcaa atccaagtta tggaacacaa
     6241 ttatcaatca tcaattatag tcaattgatt gatggtaaaa aggctgtcat tttaagtact
     6301 ccaaactcca caaatggtcg taaacacgga caaatttcga ttggtctaat taatgatgat
     6361 aatacaattg attggcgtta tcatcacgat gttgattata gtaactatgg atactcatat
     6421 tcaacattga cagagttacc aaatcatgaa attggattga tgtttgaaaa atttgattca
     6481 tggtctcgta atgaacttca tatgaaaaat gttgtaccat atataacatt taagattgaa
     6541 gatttgaaaa agaattaaag ctgaaattta aaaatatata gaaagaggat aaaaattatg
     6601 gtaaattacg gtattgttgg agctggatat tttggagctg atttggctcg ctcaatgaac
     6661 aaaattgaag atgcaaaagt ggttgcggta tttgacccaa atcatggaga agaagttgct
     6721 caagagttgg gatcagatgt ttgtgcaagt ttagatgaac ttgtagcacg tgaagatatt
     6781 gattgtgtga tcgtagcttc acctagctac cttcaccgtg aacctgttgt gaaagctgct
     6841 caacatggca aacacgtatt ttgtgaaaag ccaattgcat tgtcttatga agattgtaaa
     6901 gccatggttg acgcatgtaa agaaaataat gttatcttta tggctggtca catcatgaac
     6961 ttctttaatg gtgtacacca tgctaaagaa ttgattactc aaggtaaaat cggtaaagtt
     7021 ctttattgcc atgccgctcg tacaggttgg gaagaacaac aaccaactgt atcatggaag
     7081 aaacttcgtt ctcaatctgg aggacatttg taccaccata ttcatgaatt agattgcatt
     7141 cagttcatca tgggaggact tcctgaaaaa gcgacaatgg taggaggcaa tgtatatcat
     7201 aaaggtgaaa actttggtga tgaagatgat atgctcattg taaacctaga atactctgat
     7261 gatcgttatg ctgttttgga atatggtaat gctttccgtt ggggtgaaca ctacgtcttg
     7321 attcaaggaa ctgaaggagc tatcaaactt gacttgttca atactggagg tactcttcgt
     7381 gttaaaggtg aaggagaatc acacttctta gtacatgaaa ctcaagagga agatgatgac
     7441 cgtacagcta tctataccgg tcgtggtatg gatggagcaa ttgcgtacgg taaaccagga
     7501 gtacgttgcc cattatggtt acaaacatgt attgataaag aaatggaata tctacatgac
     7561 atcattaaag gtggagaaat tacagaagaa tatgaaaaac ttctcaatgg tgtagctgct
     7621 ttagaatcaa tcgctaccgc tgatgcatgt actttatcag ttaaagaaga tcgaaaagta
     7681 agtctttcag aaatcacaaa tgcttaacta ttgtaaaaca gaatagtaaa ttcttgtcat
     7741 tatataattt ctaaagttct gtgatacaac tcattgaata aagaaataga gatgggactg
     7801 ggataatgcc cagtcccatt ttttatcaaa aagtaatgag atcaaaaatg tgggagtgat
     7861 gaaatgaaga ttatagggat cgatattggc ggaacaacaa ttaaggcaga tttatacgat
     7921 gattttggaa cgagtttaaa tcagttcaaa gagatagaaa caattattga ctatgatttg
     7981 ggaacgaacc agatattaaa tcaggtctgt gatttaattg gtgagtatgt tttaaattat
     8041 tcaattgatg gtgttgggat ttccactgct ggagttgtta atgctaatac aggagaaatc
     8101 atctatgcag gctatacaat accagggtat atcggagtaa actttacttc cgaaatagaa
     8161 aaacgttttg ggttgtctac ttttgttgaa aatgatgtta attgtgctgc attaggtgaa
     8221 ttgtgggagg gacaagccaa agataagaaa aatgtagtaa tggttactat tggaacaggt
     8281 ataggaggca gtattattgt caatggacaa attgttaacg gatttaacta tactgctggt
     8341 gaagtaggct atattcctgt aggtaattcg gattggcaaa gcaaagcctc aacaaccgca
     8401 ttgattcatt tatatcaaaa gaagagcttg aaaactaatc aaactggacg tactttcttt
     8461 actgatttaa gttctggaga taaagtcgct aaagaaactt ttgaaatttt tgtagaaaat
     8521 ctaacaaaag gtttattaac tatttcttat ctacttaatc cagaaattct catattagga
     8581 ggtgggattc tggctaaaaa ggatattttg ttacctgaaa ttcaaagttc tttagctaaa
     8641 aatgcaatgg ataataggtt tttgcctaaa aatgttgtgg cagctacatt aggaaatgaa
     8701 gctggtcgta taggagctgt aaaaaatttc ttagatagaa tttctaataa atagtgtgaa
     8761 agataaggag gtgtcacaat gactaactct gtattttcga caatgcaaga tattgagaat
     8821 gttgcaaccg atattataaa atcatatgat aatgagattt atacgtataa agctgtctcc
     8881 caagaagaat tggaaaaact agaaaaaagt tatgatgaaa aaagtcacga agaattaatt
     8941 tcaatagaaa gcaatttaga aatgaaacaa cagaacctca ttgatgaggt taataaaaca
     9001 atcaaggaaa atgatgcaaa gattcagtat atttcatcaa gtaggagagg agaatttgta
     9061 gaaaaaatta ttggtagggt ggtagaaaaa tatggctatt agtcagatga aaagaatttc
     9121 tctactattt actaagagta gtcttgatga tgttttaaaa actattcaag aactagagtc
     9181 agtgcagttc cgtgatttaa aggttcagga taactggtca gaagcgctag aaaaagatga
     9241 ggttgtattt tcaactattc aaatttctca cacttctaat tcccatcatg gggttattga
     9301 aggaaatgat gccttgaatt atttgatgaa taaacaacaa catttggaag caactgtaga
     9361 gaaattacaa gaatacctac cgaaagaaaa cacgtttaag ttattacagc aacctccgat
     9421 aacaacctct tatgaagaat tagaaaaatt tggtaaagct aatgttgctg agggtgttct
     9481 taaaaaagtg aatcatcaaa taaacagagt tcatgaatta gaaagaaaca ttcaaagtaa
     9541 taatgaggaa atagagagat taataaagtg ggaaaaatta gaaattattc ctgcgcattt
     9601 agaacaattt tctttctgta gaggaaaagt cggaacaatt ccaaggactg tagataatcg
     9661 cttatacaat aattttttag aaaacaatat tgaagttcaa gaaatatttt ctaatgatag
     9721 agagtacggt gttgttgttt tctatcagtc cagttgctct attgattttg atgaatactt
     9781 atttgaacca tttgattatt ctagaaagga attaccgaag cagcgagtag tagatttgga
     9841 tcaagaaaac atgcagttaa taactgaaaa agagaatatt atcgcatcgt tgcaagattc
     9901 aaagaaaaat ttgatagatt tacaatggca aattgactat attttatcta tctatgctcg
     9961 tcaaatctct aagaataacc ttttgagcac tccgcatcta gttgcattag aaggatggat
    10021 agaagaaact cgtattttat attttataaa agttatggat gagcgttttg gacattctat
    10081 ttatatttat gaatcggaaa cattgtcgga taatcaagat gaaataccta tcaaattaac
    10141 gaatcactct ttaattgaac catttgaatt attgacagaa atgtatgctc tgcccaaata
    10201 ttatgagaaa gatcctacac ctgtattagc accattttac tttacatttt ttggaatgat
    10261 ggttgctgat ttaggctatg gtttactatt gtttttagga ataatgttag cattaaaaat
    10321 ttttcatcta ccttcagtaa ctaagaaatt tttaaaattc tttaatatat taggggtagc
    10381 cgttgcaatt tggggtggaa tctatggctc attttttgga tatgagttgc catttcatct
    10441 gataactaca acctcggatg tcatgactat attagtagtg tcagttgtgt ttggatttat
    10501 tacagtattt gtaggtttgt tagcttcagg actacaaaaa gtaagaatga agaaatatgc
    10561 agaagcatat aattcaggat ttgcgtggtg tgttattctg cttggcttgt tatttattgc
    10621 tgtcggaatg ttgatgcctg atattagacc gttatttgta ttagggaaat gggtatctat
    10681 ttttaatgct gtggggattt tgattgcttc tattattcaa gccaaaagct tgtcaggtat
    10741 tggctcagga ttgtttaatc tatataacat ttcatcttat ataggtgatt tagttagttt
    10801 cactcgattg atggcattag gattatctgg agcaagtata gcatcagctt tcaatttaat
    10861 tgttggtttg tttccgggga cattggctaa actgacaatt ggattagtat tattcattct
    10921 tttacatgcg atcaatattt ttctatcgtt actatcagga tatgttcatg gagcgcgtct
    10981 gatatttgtt gaattttttg gtaagtttta tgagggtgga ggaaaaccat ttcaaccttt
    11041 gaaggcttct gagaaatata ttaaggttat tacaaagaat taatggagga tatatataat
    11101 ggaacattta gcaacttatt tttcaaccta tggaggagct ttcttcgctg cattgggaat
    11161 tgtattggcg gttggattaa gcggtatggg gtctgcttat ggagttggta aggctgggca
    11221 atctgccgca gctttactga aagaacagcc agaaaaattt gcctcagctt tgatattgca
    11281 actattgccc ggaacacaag gattatatgg ttttgttatt ggaattttga tttggttgca
    11341 attaactcca gaacttcctt tggaaaaagg cgttgcttat ttctttgtag ctcttccaat
    11401 tgctattgta ggatactttt cggctaagca tcaaggaaat gtagcagtag cgggaatgca
    11461 aatcttggct aaaagaccaa aagaattcat gaagggagca attttggctg ccatggtaga
    11521 aacctatgca attcttgcct ttgtcgtatc attcattttg acccttcgtg tataagaaat
    11581 taatttgcta ttcaaaggag gtgtctaaat gagcaattta gaaaacttac gagaatctgt
    11641 tattgaacaa gctcatgaaa aagggagtat gaaattattg gattccaaaa agaagattga
    11701 tgatgaattt gaaatgcaaa agtcggtcat tgtaaagaaa aaagaagctg aacatgaacg
    11761 aaagttaaaa gaattacaac agaaatatca aataattttt caacaattaa aaaataagga
    11821 acgccaatca acgttagtat caaaacagaa aatattaaaa gaactttttc aatctgcttt
    11881 aatagaaatg gaatcttgga gtgcagataa agaaatggag ttcatctatc gaattctgga
    11941 acgatattca caacaagagg tcatagtaac ttttggggag cggactttag ctaaattcaa
    12001 tttggaacaa ttagagaaat tgaaattctc ttttccaaat catttattta gtgaacagcc
    12061 tatctcaaat gaatcaggct tacttatttc aataggtaaa attgatgata actatttgta
    12121 taaaacgtta attggatcga tttctaagga agaaagttca agtatcgcaa atcaaatttt
    12181 tatcaattaa ggatgaaatt ggttaatcct tcttagaaat ttggagtatt ccaataaaat
    12241 tagaaaggta ttttatggat actaatcttt tttcaaaaat aaatacgacg atttcggtaa
    12301 aagaaaacga ttttattaca gaagaaaaat ttcaaaaaat tatacaatcc aaagatacgg
    12361 agacattggc atttatctta gaagcaactc cctatcattt atcgattgac gttttagaaa
    12421 atcctagtca gacagagatt tcgctaatga caaaattagt caatgattat agatgggcct
    12481 atgctgaaag tccgtctgat aaaattgtga ctttatttgc tttacgatat gtttatcata
    12541 atatcaaagt tttattaaaa tctaaggcgg caattaagaa agatttttct aaattattaa
    12601 ttccaatagg gatttttgat atagaaagtt taaaacattt agtttcttcc ttacattcag
    12661 atacacttcc tgattttatg gttcatgaag tagaatcaat ttggaatgag tatgaaactt
    12721 ttaataatat tcgtgtactt gatgtcggag ctgatctagc atattttaaa catctgaaac
    12781 ttttatctaa tgagttaggt gaggtgctgt ctcaggttat tgttgcaatg attgactttt
    12841 ataatattat tactgtaaaa cgtggtttat ctcaaaataa gagtcatggg gatattttac
    12901 aattactttc agatgaagga agtatttctg ctaaagaatt tatatacatt gtagaaaatc
    12961 aagaaatatt tgtgtggttc aataaaataa atccaagctt agattcaatc ttttcaactt
    13021 acgaattgaa gatgcaggac gcaacaattt catcttctga gttagaattt ttatgtgatt
    13081 tactattgta taaaacttta gatcaaggaa ggtataatgt agatgggccg ttagttcttg
    13141 ctagatattt attgggatgt gagtttgaag taaagaatct tagaatgatc atatcagctc
    13201 ttcaaaatac aattcctttt gaatcaataa aagaaaggat acgcccgcat tatggaagct
    13261 aataagtata aaattggcat aattggtagc catgatatta ttttaccctt tagcatgatt
    13321 gggtttgata tattttctgc ctatcaagaa caagaagcta taaatactct aagaaaatta
    13381 gctcaatctg attatggtgt catttatatc actgaagaca ttgcttcaat gatattagat
    13441 acaattcgcc attatgattc tcaagttgtg cctgctatta ttttattacc gactcataaa
    13501 caaggtttaa atttaggatt aaaacgtata gaggataatg tagagaaagc agtaggacac
    13561 aatattttat aataatgtac aaaattgtct gtaatattat tctataattt ttggacttag
    13621 taaggagaat aactttgact caagggaaga ttataaaagt atcgggacct ctagttattg
    13681 catcaggtat gcaggaggct aatattcaag atatttgccg tgtaggtaag ctagggttaa
    13741 tcggtgaaat tattgaaatg agaagagatc aggcatctat ccaagtctat gaagaaacat
    13801 ctggtcttgg tccgggagaa cctgttgtta caactggaga acctctctcg gttgaattag
    13861 ggccaggatt gatttctcaa atgtttgatg gcatacaacg cccattagat cgatttaaat
    13921 tggctactca taatgatttt ctagttcgtg gggtagaagt tccaagtttg gatagagata
    13981 ttaagtggca ttttgattcc actatagcaa ttggtcaaaa agtgagtacg ggtgatattc
    14041 ttggaactgt caaggaaacc gaggtagtta atcataaaat tatggttcct tatggagtat
    14101 ctggagaagt cgtttctatt gcatctggcg attttacaat tgatgaagtt gtatatgaaa
    14161 taaaaaaatt ggacggtagt ttctataaag gaacgcttat gcaaaaatgg cctgtccgca
    14221 aggcgcgtcc tgtttctaaa cgtttaattc cagaagaacc attaatcaca ggtcaacgag
    14281 ttattgatgc attctttcca gtaaccaaag ggggagctgc agcagttcct ggaccgtttg
    14341 gagcaggaaa gacagttgta caacaccaag tagctaaatt tgccaatgtt gatattgtta
    14401 tttatgtcgg ttgtggagaa cgtggaaatg aaatgacgga tgtactgaat gagtttcctg
    14461 agttgattga ccctaatacc ggacaatcaa ttatgcaacg gacagttctg attgctaata
    14521 cttcaaatat gcctgttgct gctcgtgagg cttcaattta tacaggaatt accatggctg
    14581 agtattttcg tgatatgggc tactctgtcg ccattatggc tgattcaact tcacgttggg
    14641 cagaagcgct acgtgaaatg tcaggacgtc tagaagaaat gcctggtgat gagggttatc
    14701 ctgcttatct gggaagtcgt atcgctgaat attatgaaag agcaggacgt tctcaggttc
    14761 tagggcttcc agaacgtgaa ggaacgatta ctgctattgg agctgtatcg ccacctggtg
    14821 gagatatttc agaaccagtt actcaaaaca ctttacggat tgtgaaagtt ttttgggggc
    14881 ttgatgctcc gttggcacag cgacgtcatt ttcctgcaat taactggctt acatcttatt
    14941 cactatataa agacagtgtg ggcacttata tagatggtaa agagaagaca gattggaata
    15001 gtaaaataac tcgtgcgatg aactacttac aacgggaatc tagtttagag gaaattgttc
    15061 gtcttgttgg aattgattct ctgtctgata atgaacgact aacgatggaa attgctaaac
    15121 aaattcgaga agattatttg caacagaacg cttttgattc ggtagataca ttcacttcgt
    15181 ttgcaaaaca agaagcaatg ctaagtaata ttctcacttt tgctgatcag gcaaatcatg
    15241 ctttagagtt gggttcttac tttacagaga ttatggaagg taccgtggca gttcgagacc
    15301 gtatggcgag aagtaaatat gtttcagaag atagattaga tgaaatcaaa attatatcaa
    15361 atgagattac acatcaaatt catttgatat tagaaacagg aggtctataa atgagtgtta
    15421 taaaagaata cagaactgct agtgaagttg ttgggcctct tatgattgtt gaacaagtaa
    15481 ataatgtgtc ttacaatgag ttagttgaaa ttcaacttca taatggagaa attcgtcgtg
    15541 gacaagtttt agagatccac gaagataaag caatggttca gctttttgaa ggatctagtg
    15601 gaataaattt agaaaagtct aaaattcgtt ttgctggtca tgcattagaa ttggctgtat
    15661 ctgaggatat ggttggtcgt atttttaatg ggatgggaaa accaattgat ggtggaccag
    15721 atttaattcc agagaaatat ttagatattg atggtcaagc tattaatcct gtatctagag
    15781 attatccaga tgaatttatt cagacaggga tctcctctat tgatcatttg aatactcttg
    15841 tacgtggtca aaaattacca gtattttcag gttcgggctt acctcataat gaattagctg
    15901 ctcagatagc aagacaagcg actgttttaa attctgatga aaattttgcg gttgtatttg
    15961 cagcaatggg tattactttt gaagaagctg agttttttat ggaagaactc agaaaaacag
    16021 gagcgatcga tcgttcggtt ttatttatga acttggcaaa tgatcctgca attgagcgta
    16081 ttgcaactcc ccgcattgct ttaactgcgg cagagtatct agcttttgaa aaagatatgc
    16141 acgttctagt tatcatgacg gatatgacta actattgtga agcgttacgt gaagtctcgg
    16201 cagctcgccg tgaagttcca gggagacgag gctatccggg atatttatat acaaatttat
    16261 caactctata cgaaagggct ggtcgcttag ttggtaaaaa aggttcggtg acacagattc
    16321 ctattttaac aatgccagaa gatgacataa cacatccaat tcctgattta actggataca
    16381 ttactgaagg gcaaattatt ttgtcgcatg agttgtataa tcaaggttat cgtccaccaa
    16441 tcaatgtttt accttctctc tctcgattaa aagataaggg atctggagaa ggtaaaactc
    16501 gtggagatca tgctccaact atgaatcaac tgtttgcagc ctatgcccaa gggaaaaagg
    16561 ttgaagagtt agcagtagta ttaggagaat cggctttatc tgatgtagat aaattgtatg
    16621 tgaggtttac aaagcgtttt gaagaagagt acataaacca aggattttat aaaaatcgaa
    16681 atatagaaga tacgttgaat cttgggtggg aattactatc aattcttcct agaacagagt
    16741 taaaacgtat caaagatgat ttgcttgata aatacttacc tttggtagaa gtttaatccg
    16801 gaaatggagt gattatctat ggtacgtttg aatgtaaaac caactcgtat ggaattgaat
    16861 aacttaaagg aacgtttgac aacagctgaa cgtggacata agttattaaa ggataaaaga
    16921 gatgaattga tgaggcgatt tatttctttg attcgtgaga ataatcaact tcggaaagaa
    16981 gtggaaagtt atctaattga taatctaaaa tcctttgcag ttgctaaatc attaaagaat
    17041 tctcaaatgg tggaggaatt attttcaatt ccatcgaaag aaattgaatt atttgttgag
    17101 aaagaaaata tcatgagtgt aacagttcct agaatgcata tgaatattac ttctcaaaat
    17161 gagaacagtg aatacagcta tttatcttct aatagtgaaa tggatgatgt atttgctaca
    17221 atgaatagtt taatttataa attactaaga ctggcagaag ttga
//
LOCUS       DAVHTH010000042        17195 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.042, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000042 DAVHTH010000000
VERSION     DAVHTH010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17195)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17195)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17195
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.042"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            63..800
                     /gene="erm(B)"
                     /locus_tag="VVR63_001500"
     CDS             63..800
                     /gene="erm(B)"
                     /locus_tag="VVR63_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HEU6129509.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESRASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTITYEQVLSIFNSYLLFNGRK"
     gene            complement(1057..2304)
                     /locus_tag="VVR63_001501"
     CDS             complement(1057..2304)
                     /locus_tag="VVR63_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEU6129510.1"
                     /translation="MSHNDSILNILGIKDKNIKIISVEEAEHNNDSVKEYITLITATL
                     SYPINRCRNCGFPTVNKDGFRKTHVRLASLNGRRYELELRKQRYKCKSCHTTFGAITN
                     LTKENQTLSSDLKNQIMLLARKGLSGQLIAEMCHCSPSSVRRTILERMEPHYRVAKLP
                     KHLCFDEFRSIKSVMSFICCDAETHQIVTKLQDRLSPTIVDYFESRYSKAERECVQSV
                     VIDLNAQYQSFIYRLFPNANIIIDRFHLVQLAGRALDNCRISILKQLDKQSQEYKIMK
                     SHWKLFHKKAEDLHPEEVVFLRGVKQYMTRQNAVDLITSKFSKFAEVYQTYQDITKAL
                     NERNSELLESTILDYQKTNTEMDTAIQTLRQNRKYVLNSAKFEYSNGPLEGINRKIKT
                     LKRTCYGFANQKFFFLRIDCIFS"
     gene            2484..2705
                     /locus_tag="VVR63_001502"
     CDS             2484..2705
                     /locus_tag="VVR63_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6129511.1"
                     /translation="MNFGQNLYNWFLSNAQSLVLLAIVVIGLYLGFKREFSKLIGFLI
                     IAIIAVGLVFNAAGVKDILLELFNRIIGA"
     gene            2822..3319
                     /locus_tag="VVR63_001503"
     CDS             2822..3319
                     /locus_tag="VVR63_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000342537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HEU6129512.1"
                     /translation="MDDMQVYIANLGKYNEGELVGAWFTFPIDFEEVKEKIGLNDEYE
                     EYAIHDYELPFTVDEYTSIGELNRLWEMVSELPEELQSELSALLTHFSSIEELSEHQE
                     DIIIHSDCDDMYDVARYYIEETGALGEVPASLQNYIDYQAYGRDLDLSGTFISTNHGI
                     FEIVY"
     gene            3294..3800
                     /locus_tag="VVR63_001504"
     CDS             3294..3800
                     /locus_tag="VVR63_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016897981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEU6129513.1"
                     /translation="MGFLKSSIKSVGTLLLADFLFYGVAQSATPIFYERIDYMKKIRS
                     YTSIWSVEKVLYSINDFRLPFPITFTQMTWFVVSLFAVMILGNLPPLSMIEGAFLKYF
                     GIPVAFTWFMSTKTFDGKKPYGFLKSVIAYALRPKLTYAGKKVTLGRNQPQEAITAVR
                     SEFYGISN"
     gene            3784..6231
                     /locus_tag="VVR63_001505"
     CDS             3784..6231
                     /locus_tag="VVR63_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEU6129514.1"
                     /translation="MAYPIKYIENNLVWNKDGECYAYYELVPYNYSFLSPEQKIQVHD
                     SFRQLIAQNRDGKIHALQISTESSIRSAQERSKNEVTGKLKAVAYDKIDQQTDALISM
                     IGENQVNYRFFIGFKLLLNDQEFSMKSLTVEAKNALSDFVYDVNHKLMGDFVSMSNDE
                     ILRFQKMEKLLENKISRRFKIRRLDKDDFGYLIEHLYGQTGTAYEEYEYHLSKKKLDN
                     ETLIKYYDLIKPTRCLVEEKQRYLKIQQEDETVYVAYFTINSIVGELDFPSSEIFYYQ
                     QQQFTFPIDTSMNVEIVANRKALSTVRNKKKELKDLDNHAWQSDNETSSNVAEALESV
                     NELETNLDQSKESMYKLSYVVRVSANDLDELKRRCNEVKDFYDDLSVKLVRPFGDMLG
                     LHEEFLPASKRYMNDYIQYVTSDFLAGLGFGATQMLGENEGIYVGYSLDTGRNVYLKP
                     ALASQGVKGSVTNALASAFVGSLGGGKSFANNLIVYYAVLYGAQAVIVDPKAERGRWK
                     ETLPEISHEINIVTLTSDEKNKGLLDPYVIMKNPKDSESLAIDILTFLTGISSRDGER
                     FPILRKAIRAVTNSEVRGLMKVIEELRVENTPLSTSIADHIESFTDYDFAHLLFSNGY
                     VEQSISLEKQLNIIQVADLVLPDKETSFEEYTTMELLSVAMLIVISTFALDFIHTDRS
                     IFKIVDLDEAWSFLQVAQGKTLSMKLVRAGRAMNAGVYFVTQNTDDLLDEKLKNNLGL
                     KFAFRSTDLNEIKKTLAFFGVDPEDENNQKRLRDLENGQCLISDLYGRVGVIQFHPVF
                     EELLHAFDTRPPVRKEV"
     gene            6234..8411
                     /locus_tag="VVR63_001506"
     CDS             6234..8411
                     /locus_tag="VVR63_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEU6129515.1"
                     /translation="MKPSIVNRIKSNWTLKRLGKVAMTVAFTLVIAIFLLAMLGTVVQ
                     AAGLVDDTVNVANEYSRYPLENYQLDFYVDNSWGWLPWNWSDGIGKQVMYGLYAITNF
                     IWTISLYVSNATGYLVQEAYSLDFISATADSIGKNMQTLAGVSANGFSTEGFYVGFLL
                     LLILVLGVYVAYTGLIKRETTKAIHAIMNFVLVFILSASFIAYAPDYIKKINDFSSDI
                     SNASLSLGTKIVMPHSDSQGKDSVDLIRDSLFSIQVQQPWLLLQYNSSDIESIGIDRV
                     ESLLSTSPDSNNGEDREKIVAEEIEDRSNTNLTITKTINRLGTVFFLFVFNIGISIFV
                     FLLTGIMIFSQVLFIIYAMFLPVSFILSMIPSFDGMSKRAITKLFNTILTRAGITLII
                     TTAFSISTMLYTLSAGYPFFLIAFLQIVTFAGIYFKLGDLMSMFSLQSNDSQSVGSRV
                     MRKPRMLMHAHMHRLQRKLGRSMTTLGAGSAIVTGKKGQSGSGSSARTQADHSRPDGK
                     EKSTLGKRIGQTIGTVADTKDRMVDTASGLKEQVKDLPTNARYAVYQGKSKVKENVRD
                     LTSSISQTKADRASGRKEQQEQRRKTIAKRRSEMKQVKQKKQPASSVHERPTTRQEQY
                     HDEQTSKQSNIQTSYKESQQAKQERPAVKSDFSSPKVERQGNTVQEKTVQKPATSTTT
                     ADRTSQRPITKERPSTVQRVPLQNTRSRPPIKTATIKKVGKKP"
     gene            8408..9409
                     /locus_tag="VVR63_001507"
     CDS             8408..9409
                     /locus_tag="VVR63_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HEU6129516.1"
                     /translation="MKLKTLVIGGSGLFLMVFSLLLFVAILFSDEQDSGISNIHYGGV
                     NVSAEVLAHKPMVEKYAKEYGVEEYVNILLAIIQVESGGTAEDVMQSSESLGLPPNSL
                     STEESIKQGVKYFSELLASSERLSVDLESVIQSYNYGGGFLGYVANRGNKYTFELAQS
                     FSKEYSGGEKVSYPNPIAIPINGGWRYNYGNMFYVQLVTQYLVTTEFDDDTVQAIMDE
                     ALKYEGWRYVYGGASPTTSFDCSGLTQWTYGKAGINLPRTAQQQYDVTQHIPLSEAQA
                     GDLVFFHSTYNAGSYITHVGIYLGNNRMFHAGDPIGYADLTSPYWQQHLVGAGRIKQ"
     gene            9406..10338
                     /locus_tag="VVR63_001508"
     CDS             9406..10338
                     /locus_tag="VVR63_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEU6129517.1"
                     /translation="MRKEDLMMKFRKNQNKEKQIPKEKKPRVYKVNPHKKVVIALWVL
                     LGLSFSFAIFKHFTAIDTHTIHETTIIEKEYVDTHHVENFVENFAKVYYSWEQSDKSI
                     DNRMESLKGYLTDELQALNVDTVRKDIPVSSSVRGFQIWTVEPTGDNEFNVTYSVDQL
                     ITEGENTKTVHSAYIVSVYVDGSGNMVLVKNPTITNIPKKSSYKPKAIESEGTVDSIT
                     TNEINEFLTTFFKLYPTATASELSYYVNDGILKPIGKEYIFQELVNPIHNRKDNQVTV
                     SLTVEYIDQQTKATQVSQFDLVLEKNGSNWKIIE"
     gene            10583..10699
                     /locus_tag="VVR63_001509"
     CDS             10583..10699
                     /locus_tag="VVR63_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HEU6129518.1"
                     /translation="MILKYPENICMLCMPMVMHKNPSDKSIYHWDFYALLGF"
     gene            10715..12624
                     /gene="tet(M)"
                     /locus_tag="VVR63_001510"
                     /pseudo
     CDS             10715..12624
                     /gene="tet(M)"
                     /locus_tag="VVR63_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
     gene            12743..12910
                     /locus_tag="VVR63_001511"
     CDS             12743..12910
                     /locus_tag="VVR63_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HEU6129519.1"
                     /translation="MCPVCGNKTRLKIREDTELKKFPLYCPKCRQENLIEIKQFKVTV
                     ITEPDAKTQSR"
     gene            complement(12970..13323)
                     /locus_tag="VVR63_001512"
     CDS             complement(12970..13323)
                     /locus_tag="VVR63_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU6129520.1"
                     /translation="MRKKEDKYDFRAFGLAIKEARLKRGLTREQVGALIEIDPRYLTN
                     IENKGQHPSIQVLYDLVSLLHVSVDEFFLPANNLVKSTRRLQIEKYMDSFTDKELSLM
                     ESLASGINEARNIED"
     gene            13828..14250
                     /locus_tag="VVR63_001513"
     CDS             13828..14250
                     /locus_tag="VVR63_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006733729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEU6129521.1"
                     /translation="MKPSSFQTTIENQFDYICKRAMEDERKNYMLYLSRIAKREVSFS
                     DVGDYLVSQFATTDNYSTDFQIFTLNGLSVGVENDLLSEALRELPDKKREILLLFYFM
                     DMSDSEIADLLKLNRSTVYRHRTSGLALIKKFMEEFEE"
     gene            14247..14477
                     /locus_tag="VVR63_001514"
     CDS             14247..14477
                     /locus_tag="VVR63_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU6129522.1"
                     /translation="MKTQYPMIPFPLIVKATDGDTEAINQILHHYRGYITKRSLRLMK
                     DEYGNQSMVVDEVLRGRMETRLITKILSFEIK"
     gene            14938..15141
                     /locus_tag="VVR63_001515"
     CDS             14938..15141
                     /locus_tag="VVR63_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006730246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HEU6129523.1"
                     /translation="MKQTDIPIWERYTLTIEEASKYFRIGENKLRRLAEENKNANWLI
                     MNGNRIQIKRKQFEKIIDTLDAI"
     gene            15223..16439
                     /locus_tag="VVR63_001516"
                     /pseudo
     CDS             15223..16439
                     /locus_tag="VVR63_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020220015.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
     gene            complement(16654..>17195)
                     /locus_tag="VVR63_001517"
     CDS             complement(16654..>17195)
                     /locus_tag="VVR63_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU6129524.1"
                     /translation="LVSLYLLKLLCISELTILQILYCASLISFLWMYGQRKQVVKVNM
                     KTRMKWLGIGFVSLLIINLCFSLIHAQGTTNQANLIGLQHQVPWFSFLLLLINASMVE
                     EFLYREILWNLVRKLDIRVALTSILFVLAHHPGTILAWCLYVSLGMFLGLVRYKSDLW
                     GSMGLHLVWNLSVYVLFFL"
BASE COUNT         5663 a         3055 c         3468 g         5009 t
ORIGIN      
        1 tacaaacaaa tcgtttaact tctgtatttg tttatagatg taatcacttc aggagagatt
       61 acatgaacaa aaatataaaa tattctcaaa actttttaac gagtgaaaaa gtactcaacc
      121 aaataataaa acaattgaat ttaaaagaaa ccgataccgt ttacgaaatt ggaacaggta
      181 aagggcattt aacgacgaaa ctggctaaaa taagtaaaca ggtaacgtct attgaattag
      241 acagtcatct attcaactta tcgtcagaaa aattaaaact gaatactcgt gtcactttaa
      301 ttcaccaaga tattctacag tttcaattcc ctaacaaaca gaggtataaa attgttggga
      361 atattcctta ccatttaagc acacaaatta ttaaaaaagt ggtttttgaa agccgtgcgt
      421 ctgacatcta tctgattgtt gaagaaggat tctacaagcg taccttggat attcaccgaa
      481 cactagggtt gctcttgcac actcaagtct cgattcagca attgcttaag ctgccagcgg
      541 aatgctttca tcctaaacca aaagtaaaca gtgtcttaat aaaacttacc cgccatacca
      601 cagatgttcc agataaatat tggaagctat atacgtactt tgtttcaaaa tgggtcaatc
      661 gagaatatcg tcaactgttt actaaaaatc agtttcatca agcaatgaaa cacgccaaag
      721 taaacaattt aagtaccatt acttatgagc aagtattgtc tatttttaat agttatctat
      781 tatttaacgg gaggaaataa ttctatgagt cgctttttta aatttggaaa gttacacgtt
      841 actaaaggga atggagataa attattagat atactactga cagcttccaa gaagctaaag
      901 aggtccctag cgcctacggg gaatttgtat cgataagggg tacaaattcc cactaagcgc
      961 tcgggacccc ttgtaggaaa atgtcctaag tgggatatct gtcaactggt atggttgact
     1021 aaaaatactt cctacgaaaa tgtagggggt atttttttac gaaaaaatac aatcgattct
     1081 taaaaagaaa aatttttgat tggcaaaacc ataacaagtt cgttttaggg ttttgatttt
     1141 gcgattgatg ccttctaaag gaccattaga gtattcaaat ttagcgctat ttaagacata
     1201 ttttctgttt tgacgaaggg tttgaatagc agtatccatt tctgtattgg ttttttggta
     1261 gtctaagatg gttgactcta gtaattcact attgcgctcg tttagggctt tcgtgatatc
     1321 ttggtaagtt tggtatactt cagcgaactt ggaaaattta ctagtaatga gatcaacagc
     1381 attttggcga gtcatatatt gtttaacgcc gcgaagaaaa actacttctt cagggtgaag
     1441 atcttcagct tttttatgga atagcttcca atgtgacttc ataattttat attcttggct
     1501 ctgtttatca agttgcttta ggatagagat acgacaattg tccaaagcgc gaccagctaa
     1561 ttgtacaagg tggaagcgat caataatgat attggcatta gggaaaaggc gatagataaa
     1621 actttgatat tgagcattta aatcaattac aactgattga acgcattcgc gttcggcttt
     1681 tgaataacga ctttcaaaat aatcaacaat ggtaggtgat agacgatcct gtaactttgt
     1741 gacaatttgg tgggtttcag cgtcacaaca gataaaggac atcacagact taattgaacg
     1801 aaactcgtca aaacatagat gcttaggcaa cttagccaca cgatagtgtg gttccatgcg
     1861 ctctaagatt gttcgacgaa cactgctagg agagcagtga cacatttcag caataagctg
     1921 accagataag cctttacgag ctaaaagcat gatttgattt ttgagatcac tggataaggt
     1981 ttgattttct ttggttaaat tagtaatagc accaaaagta gtatggcatg atttacattt
     2041 atagcgttgt ttacgaagct ctagttcata tcttctccca tttaaacttg ccagtcgtac
     2101 atgagttttg cgaaagccat ccttattaac tgtgggaaag ccacagttac gacaacgatt
     2161 aatcggataa gaaagagtag ctgttattag cgttatatac tctttaacag aatcgttgtt
     2221 gtgttcagct tcttcaacag aaataatttt aatattttta tctttaattc caagaatatt
     2281 taggatagaa tcattatggg acatttgttt aaccttcttt catgattttt gtggtgaatt
     2341 gattgtataa cgaggggaca gcaaatgtcc tcttttttgt ataaaaaaat ctggcatgga
     2401 atctctatcc ataccagaaa gtgtataccc caaaaaaata actcaaatac aaattcattg
     2461 aatatagaga ggagaacatt tttatgaatt ttggacaaaa cctttataac tggtttctat
     2521 caaacgctca atcactggtg cttttagcaa tcgttgtgat tggcttgtat cttggcttca
     2581 agcgtgagtt tagcaaactg attggctttt taattattgc gattattgcg gttggcttag
     2641 tcttcaacgc tgctggagta aaagacattt tactagagct attcaatcgc attattggtg
     2701 cttaaataaa accgttcttt tgtggaatat aagtggtttt cttatgttcc gcaaaggaat
     2761 ggtacaccaa acgaagtgcg gtagggattt ttgaatctct acaaagaaag gacgtgaata
     2821 tatggacgat atgcaagtct atattgcgaa tttaggcaaa tacaatgagg gcgaattggt
     2881 cggtgcgtgg tttacctttc ccattgactt tgaggaagtc aaagagaaaa tcggcttgaa
     2941 tgatgaatat gaggaatacg ccattcatga ctacgagtta ccctttacgg ttgacgaata
     3001 cacttccatt ggcgaactca atcgactatg ggaaatggta tcggaattac ccgaagaatt
     3061 acaatcggag ctatctgctc tgctcactca tttttcaagc attgaagaac taagcgaaca
     3121 tcaagaggat attatcattc attccgattg tgatgatatg tatgacgtgg cacgctacta
     3181 cattgaagaa acgggtgctt taggcgaagt accagctagt cttcaaaact atattgatta
     3241 tcaagcctat ggtcgggatt tagacctttc aggaacgttt atctcaacca atcatgggat
     3301 ttttgaaatc gtctattaaa tctgtcggta cattactact ggcagatttt ctattttacg
     3361 gggtggctca atcagctacc cctatttttt atgaaaggat tgattacatg aagaaaatac
     3421 gaagctatac cagtatctgg tctgtggaaa aggtactgta ttctatcaat gattttagac
     3481 ttccgtttcc cataaccttt acgcaaatga catggtttgt cgtgtcactc tttgcagtga
     3541 tgatacttgg caacttgccc cctctttcca tgatagaggg agcatttctc aaatactttg
     3601 ggattcctgt ggctttcaca tggtttatgt ctacaaaaac ttttgatggt aaaaagcctt
     3661 atggattttt gaagtctgtc attgcttatg cactgcgacc aaagctgacc tatgcaggaa
     3721 aaaaagtaac gcttggcaga aaccagccac aagaagccat tacagcagtt aggagtgaat
     3781 tttatggcat atccaattaa atacattgaa aacaatctcg tctggaataa agacggggaa
     3841 tgttatgctt actatgagct tgttccttac aattactcat ttctaagtcc agaacagaaa
     3901 atacaagtgc atgattcttt cagacagctt atcgcacaaa atcgtgatgg caaaattcat
     3961 gctttacaaa tcagtacaga atccagcata cgttctgcac aagagcgttc caaaaatgaa
     4021 gtcactggca agctcaaagc ggttgcctat gacaaaatcg accaacagac agacgcttta
     4081 atatccatga ttggcgaaaa tcaagtgaac taccgtttct ttatcggctt taagttgctt
     4141 ctcaacgatc aggagttttc tatgaaaagt cttaccgttg aagcaaaaaa tgctttgtct
     4201 gattttgtct atgatgtgaa ccataagctg atgggcgatt ttgttagtat gagtaatgat
     4261 gaaatcctgc gttttcagaa gatggaaaag ctcttagaaa ataaaatctc tcgtcgtttc
     4321 aaaatccgca ggttagataa ggacgacttc ggctatctga ttgaacacct ttacggacag
     4381 acaggcactg cctatgaaga gtatgagtac catctatcaa agaaaaagct ggataatgaa
     4441 acgctgatta aatactatga cttgattaag cctactcgct gtttggtgga agaaaaacag
     4501 cgatatttga aaatccagca ggaagatgaa accgtctatg tagcttactt taccattaac
     4561 agcattgtcg gagaactgga cttcccgtcc tctgaaatct tctactacca gcaacagcaa
     4621 tttacattcc cgattgatac gtcaatgaat gtggaaattg tagcgaatcg taaagcccta
     4681 tctactgtcc gcaataaaaa gaaagaactg aaagacttgg ataaccacgc ttggcaaagt
     4741 gataatgaaa ccagctccaa tgtggcggaa gctctggaaa gtgtgaatga gctggaaacc
     4801 aatttagacc aaagcaagga atctatgtac aagctgtctt atgtggtaag ggtatcagca
     4861 aatgatcttg acgaactcaa acgtcgttgt aatgaagtga aagattttta tgacgattta
     4921 agcgtaaaac tggtacgacc atttggggat atgctcggct tacatgaaga atttttacct
     4981 gccagcaagc gttatatgaa tgattatatt caatacgtga cctctgattt cctcgctggt
     5041 ttaggttttg gtgctactca aatgctgggg gaaaatgagg ggatttatgt tggctacagc
     5101 ttagatactg gacgcaatgt ctatctgaaa cctgctcttg ccagtcaagg ggttaagggt
     5161 tcagtaacca atgcgttagc gtcggctttt gttggttcgc tgggtggtgg taaatccttt
     5221 gcgaataacc ttatcgtcta ttatgcggtg ctttatgggg cacaagcagt gattgtagac
     5281 ccaaaagcag aacgtggcag atggaaagaa accttgccag agatttccca tgaaatcaat
     5341 atcgtcactc tgacttctga tgagaaaaac aaaggcttac ttgaccctta tgtgattatg
     5401 aaaaatccca aagattctga atcactggct attgatattc tgacattcct tacggggatt
     5461 tcctctcgtg atggggaacg cttcccaatc cttagaaaag ccattcgtgc agtaaccaat
     5521 agtgaagtac gagggttgat gaaagtgatt gaggaattac gggttgagaa tacgccacta
     5581 agtaccagta tagccgacca tatcgaaagt tttacagact atgactttgc acatttatta
     5641 ttcagtaatg gttatgtgga gcagtctatc agcttagaaa aacaactgaa cattatacag
     5701 gttgcggact tggtacttcc cgacaaggaa acttcctttg aggaatatac cactatggag
     5761 cttttatccg ttgctatgct gattgtcatt agtacctttg ctttagactt tatccataca
     5821 gaccgaagca ttttcaagat tgtagattta gacgaagcat ggagcttttt acaggtagca
     5881 caaggaaaaa cactatctat gaagctggtt cgggctggtc gtgctatgaa cgctggagta
     5941 tatttcgtga cccaaaatac agacgacctc ttagatgaaa aactgaaaaa taacctcggc
     6001 ttaaaatttg catttcgttc cactgacctt aacgagatta aaaagacctt agcctttttt
     6061 ggtgtagacc cagaggacga aaacaatcag aagcgattgc gtgatttgga aaacgggcaa
     6121 tgccttatca gtgatttata tggtcgtgtc ggtgtgatac agttccaccc tgtatttgaa
     6181 gaactgctcc atgcctttga taccagacca cctgtgcgaa aagaggtgta aatgtgaaac
     6241 catcaatagt aaacagaata aaatcaaact ggacgctgaa acgtctaggt aaagtggcaa
     6301 tgacagtggc tttcacactt gtgattgcca tttttctttt agccatgctg ggaacggtgg
     6361 ttcaagctgc gggcttggta gatgatacgg tcaatgtggc aaatgaatac agccgatacc
     6421 cacttgaaaa ctatcaactg gatttttatg tggataatag ctggggctgg cttccgtgga
     6481 actggtcgga cgggattgga aaacaggtca tgtatggact atatgccatt accaatttta
     6541 tttggacaat cagtttgtat gtttccaatg cgacaggtta cttagtacag gaagcctatt
     6601 ccttagactt catttccgct acagcagatt ccattggtaa gaatatgcag accttagctg
     6661 gtgtgagtgc aaacggattt tcaacagagg gtttctatgt tggattcctc ttactcttga
     6721 ttttggttct tggggtttat gttgcctata cgggactgat aaagagagaa accacaaagg
     6781 caattcatgc cattatgaat tttgtgctgg tgtttatcct atcggcttcc tttattgcct
     6841 acgctcccga ctacattaaa aaaatcaatg acttttcatc agacatcagt aatgccagtt
     6901 tatcacttgg cacgaagatt gtcatgcccc attccgatag tcaaggcaag gacagcgtgg
     6961 acttaatcag agatagcctg ttttccatac aggttcagca accgtggcta ctgcttcaat
     7021 acaacagttc agacattgaa agtatcggta ttgaccgtgt ggaaagcctg ctctccacca
     7081 gcccagattc caacaatggc gaagacagag aaaaaattgt tgcggaagaa attgaagaca
     7141 gaagcaatac caatctaacc attacaaaga ccattaaccg tttaggtaca gtcttcttcc
     7201 tatttgtctt caatattggg atttccatat ttgtattcct attaacagga atcatgattt
     7261 tctcgcaggt actttttatc atctatgcta tgtttctgcc tgtgagcttt attttaagca
     7321 tgattccatc atttgatggt atgtcaaaac gagccataac aaagctcttt aataccattt
     7381 tgacacgagc tggaatcaca ttgattatta cgacagcatt tagtatttca accatgctct
     7441 ataccttatc ggctggttat ccgttctttt tgattgcttt tctacagatt gtgacctttg
     7501 caggaatcta cttcaagctg ggcgatttaa tgagtatgtt ttctctacag agtaacgatt
     7561 ctcaaagtgt gggaagtcgt gtgatgagaa aacctcgtat gcttatgcac gctcacatgc
     7621 accgtctaca gcggaaactt ggacgttcca tgactactct aggggctggg tctgccattg
     7681 ttacaggtaa aaaaggacag tcgggttcgg ggagttctgc aaggacacaa gcagatcact
     7741 cccgaccaga cggaaaggaa aaatcaacac ttggaaaacg tatcggtcaa accatcggta
     7801 cagtagctga taccaaagac agaatggtag acactgctag tggtttgaaa gaacaggtta
     7861 aagatttgcc gaccaatgca agatatgcag tatatcaagg aaaatccaaa gtaaaagaga
     7921 atgtccgtga tttaaccagt agtatttctc aaaccaaagc ggacagagcc agtggacgca
     7981 aggaacagca ggaacaaagg cgaaaaacca ttgcgaagcg tcgctctgaa atgaaacagg
     8041 tcaaacagaa aaaacagcct gcttcttctg ttcatgaaag accgactaca agacaagaac
     8101 aatatcatga tgaacagacc tcaaaacagt ctaatattca gacttcatat aaggaatctc
     8161 aacaagccaa acaagagcgt ccagcagtta agtccgattt ttcaagtcca aaagtggaac
     8221 gccaaggcaa taccgttcaa gaaaaaaccg ttcaaaagcc agcaacttca accactacag
     8281 cagatagaac ttcacaacgt ccaatcacaa aagaacgtcc gtctactgtt caaagagtac
     8341 cactacaaaa tacaagaagt agaccaccaa tcaaaaccgc caccattaag aaagtcggta
     8401 agaaaccatg aagttgaaaa ctttagtgat tggtggttct ggattattct tgatggtctt
     8461 ctcactgctt ctgtttgttg ccattttatt ttcagatgaa caggacagcg gaatttccaa
     8521 tattcattat ggaggtgtga atgtttccgc agaagtgctg gctcataagc ctatggtaga
     8581 aaaatatgcc aaagaatatg gcgttgaaga atatgtcaac atacttcttg cgattataca
     8641 ggtggaatcg ggcggtactg cggaagatgt tatgcagtcc tcggaatccc tcggtcttcc
     8701 acctaattca ttgagtacag aagaatccat taagcaaggt gtgaagtatt tcagtgaatt
     8761 attagccagt agcgaaaggc tcagtgtaga tttagaatcg gttatccagt cctacaatta
     8821 tggtggtggt ttcttagggt atgtggctaa tcgtggaaat aaatatacct ttgaactggc
     8881 tcaaagtttc tcaaaagagt attcaggtgg cgaaaaagtg tcttacccca atcccatagc
     8941 catacctatc aatgggggct ggcgatacaa ctatggcaat atgttttatg tgcaactggt
     9001 aacgcagtat cttgtcacaa cagagtttga tgatgatacg gtacaagcca tcatggacga
     9061 agcactgaaa tatgagggct ggcgatacgt ttacggtgga gcttccccga ctacttcttt
     9121 tgattgtagc ggactgacac aatggacgta tggaaaagct ggaattaact taccacgaac
     9181 cgcacaacag caatatgatg tgacccagca tatcccacta tcggaagcac aagctggcga
     9241 tttggttttc tttcattcta cctataacgc tggctcttat attactcatg ttgggatata
     9301 ccttggcaat aaccgtatgt ttcatgcagg cgacccaatc ggttatgccg acttaacaag
     9361 cccctactgg caacagcatt tagtgggagc aggacgaatc aaacaatgag aaaggaagat
     9421 ttaatgatga aatttagaaa aaatcagaat aaagaaaaac agataccaaa ggaaaagaaa
     9481 cctcgtgtct ataaggtcaa tcctcataaa aaggttgtga ttgccttgtg ggtactttta
     9541 gggcttagtt tcagctttgc gatattcaag cactttacag ctatagatac tcatactatt
     9601 cacgaaacaa ctatcataga aaaggaatac gttgatactc atcatgtaga aaattttgta
     9661 gagaactttg cgaaagtcta ctattcatgg gagcaatccg ataagtccat tgataatcga
     9721 atggaaagtc taaaaggcta tctgacagat gaacttcaag ctctcaatgt tgatacagta
     9781 cgcaaagata ttcctgtatc gtcttctgta agaggatttc agatatggac ggtagagcca
     9841 actggcgaca atgagtttaa tgtaacctac agtgtagacc agctcattac agagggagaa
     9901 aatacaaaga ccgtccactc tgcttatata gtgagtgtct atgtagatgg ttctggaaat
     9961 atggtactgg ttaagaatcc gaccattacc aacataccta agaaatcaag ttataaacca
    10021 aaagccattg aaagtgaggg gacggttgat tccattacaa ccaatgaaat caatgagttt
    10081 ttaacgacgt tcttcaagct ctatcctaca gcgacagcca gtgaactttc ctactatgtg
    10141 aatgacggga tattaaaacc aatcggaaaa gagtacatct ttcaagaact ggtaaatcct
    10201 attcacaatc gtaaggataa tcaagtcacg gtatcgctga cagtggagta tatcgaccag
    10261 cagaccaaag caacgcaggt atctcaattt gatttggtac ttgaaaagaa cgggagtaat
    10321 tggaagatta tagaataaca aatattggta cattattaca gctattttgt aatcacgtac
    10381 tctctttgat aaaaaattgg agattccttt acaaatatgc tcttatgtgc tattatttaa
    10441 gtatctattt aaaaggagtt aataaatatg cggcaaggta ttcttaaata aactgtcaat
    10501 ttgatagtgg gaacaaataa ttggatgtcc ttttttagga gggcttagtt ttttgtaccc
    10561 agtttaagaa tacctttatc atgtgattct aaagtatccg gagaatatct gtatgctttg
    10621 tatgcctatg gttatgcata aaaatcccag tgataagagt atttatcact gggattttta
    10681 tgcccttttg ggtttttgaa tggaggaaaa tcacatgaaa attattaata ttggagtttt
    10741 agctcatgtt gatgcaggaa aaactacctt aacagaaagc ttattatata acagtggagc
    10801 gattacagaa ttaggaagcg tggacaaagg tacaacgagg acggataata cgcttttaga
    10861 acgtcagaga ggaattacaa ttcagacagg aataacctct tttcagtggg aaaatacgaa
    10921 ggtgaacatc atagacacgc caggacatat ggatttctta gcagaagtat atcgttcatt
    10981 atcagtttta gatggggcaa ttctactgat ttctgcaaaa gatggcgtac aagcacaaac
    11041 tcgtatatta tttcatgcac ttaggaaaat ggggattccc acaatctttt ttatcaataa
    11101 gattgaccaa aatggaattg atttatcaac ggtttatcag gatattaaag agaaactttc
    11161 tgccgaaatt gtaatcaaac agaaggtaga actgtatcct aatatgtgtg tgacgaactt
    11221 taccgaatct gaacaatggg atacggtaat agagggaaac gatgaccttt tagagaaata
    11281 tatgtccggt aaatcattag aagcattgga actcgaacaa gaggaaagca taattgttct
    11341 ctgttccctc tttatcatgg aagtgcaaaa agtaatatag ggattgataa ccttatagaa
    11401 gtgattacga ataaatttta ttcatcaaca catcgaggtc agtctgaact ttgcggaaaa
    11461 gttttcaaaa ttgagtattc ggaaaaaaga cagcgtcttg catatatacg tctttatagt
    11521 ggcgtactgc atttgcgaga ttcggttaga atatcggaaa aggaaaaaat aaaaattaca
    11581 gaaatgtata cttcaataaa tggtgaatta tgtaaaatcg ataaggctta ttccggggaa
    11641 attgttattt tgcagaatga gtttttgaag ttaaatagtg ttcttggaga tacaaagcta
    11701 ttgccacaga gagagagaat tgaaaatccc ctccctctgc tgcaaacgac tgttgaaccg
    11761 agcaaacctc aacaaaggga aatgttactt gatgcacttt tagaaatctc cgacagtgac
    11821 ccgcttctgc gatattatgt ggattctgcg acacatgaaa tcatactttc tttcttaggg
    11881 aaagtacaaa tggaagtgac ttgtgctctg ctgcaagaaa agtatcatgt ggagatagaa
    11941 ataaaagagc ctacagtcat ttatatggaa agaccgttaa aaaaagcaga gtataccatt
    12001 cacatcgaag ttccaccgaa tcctttctgg gcttccattg gtctatctgt agcacagctt
    12061 ccattaggga gcggagtaca gtatgagagc tcggtttctc ttggatactt aaatcaatcg
    12121 tttcaaaatg cagttatgga ggggatacgc tatggctgtg aacaaggatt gtatggttgg
    12181 aatgtgacgg actgtaaaat ctgttttaag tatggcttat actatagccc tgttagtacc
    12241 ccagcagatt ttcggatgct tgctcctatt gtattggaac aagtcttaaa aaaagctgga
    12301 acagaattgt tagagccata tcttagtttt aaaatttatg cgccacagga atatctttca
    12361 cgagcataca acgatgctcc taaatattgt gcgaacatcg tagacactca attgaaaaat
    12421 aatgaggtca ttcttagtgg agaaatccct gctcggtgta ttcaagaata tcgtagtgat
    12481 ttaactttct ttacaaatgg acgtagtgtt tgtttaacag agttaaaagg gtaccatgtt
    12541 actaccggtg aacctgtttg ccagccccgt cgtccaaata gtcggataga taaagtacga
    12601 tatatgttca ataaaataac ttagtgtatt ttatgttgtt atataaatat ggtttcttgt
    12661 taaataagat gaaatatttt ttaataaaga tttgaattaa agtgtaaagg aggagatagt
    12721 tattataaac tacaagtgga tattgtgtcc tgtatgtgga aataaaacac gattaaagat
    12781 aagggaagat actgaattaa aaaaattccc cctctattgt ccgaaatgca gacaagaaaa
    12841 tttaattgaa ataaagcagt tcaaagtaac tgtgattaca gagccagacg caaagacgca
    12901 gagccgataa aatgagatta atacaatctc attttatcgg ctctttccgt tatgtatgga
    12961 ttcttttaat tagtcttcga tgtttcttgc ttcgttgata ccgctggcta aagattccat
    13021 taaggatagt tctttgtctg taaagctatc catgtatttc tctatctgta atcgtcgggt
    13081 gctttttacc aagttattag caggtaagaa aaattcatca acggaaacat gaagtaacga
    13141 tacaaggtca taaagaactt gtatgctggg gtgttgccct ttattttcaa tattagttaa
    13201 gtaccgtggg tcaatttcaa tcaatgctcc cacttgttca cgagttaaac ctcgtttcaa
    13261 tcgagcttct ttaatggcta aaccaaaggc tctaaaatca tatttatctt cttttttacg
    13321 catagtagac cacctctata cattttattg ttcctactga attaaaaaca ggtatagaaa
    13381 aacgtgttat atggtttata ggtttatatt taataaaaag cactactaaa cgccaataaa
    13441 aaaaaccgtt atatggtagt gctatttacg ctgttaaaat attgtatatt acttccaaat
    13501 ggcggtttgt tggaggtcaa cgtcgccatg aagtacatca tatacaataa atttccttac
    13561 attgggttct tgtcaaaaaa agtcgtctat ctgcaataga taagtacgtc caccaatgtg
    13621 gttttataaa tcatatagat agaataacag aagcatgtaa acagagaaat aaatctgttt
    13681 atatgctttt ttggctattc agaacttttt tacaaagttt atttatcagt aatgcaacaa
    13741 atcccccttt cacattggga ctaagagtga aaggagataa acgagcaagg ctcacttcct
    13801 ttcctagaca gaaagggggt gagaaacatg aaaccatctt cttttcagac cacaatagaa
    13861 aatcagtttg actatatctg taaacgtgct atggaagacg agcgaaagaa ttatatgctt
    13921 tatctttcaa ggattgcaaa gcgtgaggtg tccttttcgg atgttggcga ttatcttgtt
    13981 agccagtttg cgacaacaga taactattca actgactttc agatttttac actcaatggg
    14041 ttatcagtag gcgttgaaaa tgatttgttg agtgaagcat tacgtgagtt gccagacaag
    14101 aaacgtgaaa ttctactgct gttttacttt atggacatga gcgattcaga aattgcagac
    14161 ctgttgaaat tgaaccgttc tactgtctat cggcatagaa ccagtggact agccttaatt
    14221 aaaaagttta tggaggaatt tgaagaatga aaacacaata tcctatgatt ccctttcctc
    14281 tcattgtaaa ggcaacagat ggcgataccg aagcgattaa ccagattcta catcattaca
    14341 gagggtacat aacgaagcgt tccctacgac ttatgaaaga tgaatatggc aatcaaagta
    14401 tggtcgttga tgaagtctta cgtggaagaa tggaaaccag actgattaca aagattttgt
    14461 catttgaaat taagtaatat cctctctcct ttcgtggaag cgtgctaaac cattccacgc
    14521 ttcccgaaca gggaggtttg ttattccacc aaagcatatt gagctttcaa tgtgttttga
    14581 taggctaacg agccattgtt ctttgaaaac tgaataaaag taatcgaata cgtttcgata
    14641 agaaaagagc caacggaact aaccgccatg acctatctta taaagatagc gagcgattca
    14701 tgttagtgat ccgagaagca atctttagca ggattgcctg caacgacatt cttatcgtga
    14761 taatgatact cccatacagt caatagtccg agcgtgataa aaccgtcgca ggcaatgagt
    14821 atggctacat gagaaccatg caggggtgga actcccgtga gctttgctaa agctgttcga
    14881 ttgctggtaa aacaactttt atgaaatcca aataagtgat ttggaaagga ggattttatg
    14941 aagcagactg acattcctat ttgggaacgt tataccctaa ccattgaaga agcgtcaaaa
    15001 tattttcgta ttggcgaaaa caagctacga cgcttggcag aggaaaataa aaatgcaaat
    15061 tggctgatta tgaatggcaa tcgtattcag attaaacgaa aacaatttga aaaaattata
    15121 gatacattgg acgcaatcta gcgtcgccaa agggtcttgt atatgataaa atagtattaa
    15181 gtcgtatcaa ggctctttcc ataaaggaaa ggagcaaatg ccatgtcaga aaaaagacgt
    15241 gacaataaag gtcgaatctt aaagactgga gagagccaac gaaaagacgg aagatactta
    15301 tacaaatata tagattcatt tggagaaccg caatttgttt actcgtggaa acttgtggct
    15361 acagaccgag taccagcagg aaagcgtgat tgtatctcac ttagagagaa aatcgcagag
    15421 ttacagaaag acattcatga tggtattgat gttgtaggaa agaaaatgac actctgccag
    15481 ctttacgcaa aacagaacgc tcaaagacca aaggttagaa aaaacactga aactggacgc
    15541 aaatatctta tggatatttt gaagaaagac aagttaggtg taagaagtat tgacagtatt
    15601 aagccatcag acgctaaaga atgggctatt agaatgagtg aaaatggtta tgcttatcaa
    15661 accatcaata actacaaacg ttctttaaag gcttcattct atattgctat acaagatgat
    15721 tgtgttcgga agaatccatt tgactttcaa ctgaaagcag ttcttgatga tgatactgtc
    15781 cctaaaaccg tactaacaga agaacaggaa gaaaaactgt tagcctttgc aaaagctgat
    15841 aaaacctaca gcaaaaatta tgatgaaatt ctgatactct taaaaacagg tcttcgtatt
    15901 tcagagtttg gtggtttgac acttccagat ttagattttg agaatcgtct tgtcaatata
    15961 gaccatcagc tattgagaga tactgaaatt gggtactaca ttgaaacacc aaagaccaaa
    16021 agtggcgaac gtcaagttcc tatggttgaa gaagcctatc aagcatttaa gcgagtgtta
    16081 gcgaatcgaa agaatgataa gcgtgttgag attgatggat atagtgattt cctctttctt
    16141 aatagaaaga actatccaaa agtgcaagtg attacaacgg catgatgaaa ggtcttgtta
    16201 agaaatacaa taagtataac gaggataaat tgccacacat cactccacat agtttgcgac
    16261 atacattctg taccaactat gcaaatgcag gaatgaatcc aaaggcatta cagtacatta
    16321 tgggacatgc taatatagcc atgacgctga actattacgc acatgcaaca ttcgattctg
    16381 caatggcaga aatgaaacgc ttgaataaag agaagcaaca ggagcgtctt gttgcttagt
    16441 agtacaaatg aatttactac ttatttacca cttctgacag ctaagacatg aggaaatatg
    16501 caaagaaacg tgaagtatct tcctacagta aaaatactcg aaagcacata gaataaggct
    16561 ttacgagcat ttaagaaaat ataaaaagat aattagaaat ttatactttg tttatttcaa
    16621 aattaatcca tgcttaagac agaccagcta ttattaaaga aaaaataaga catagactga
    16681 taggttccac accaaatgta gccccatact gccccataag tccgatttgt agcgcacaag
    16741 ccctaaaaac atcccaagtg aaacatacaa acaccaagct aaaatggttc ctggatgatg
    16801 agctaagaca aataaaatac ttgtcaaagc aactcgaata tctaattttc taaccaagtt
    16861 ccataaaatt tctcgataca gaaattcttc aaccatactc gcattgatta ataacaataa
    16921 aaatgaaaac caagggactt gatgttgaag gccaattaag tttgcttgat tcgtagttcc
    16981 ttgagcatgg attaggctaa aacatagatt tataatcagt aggctaacga atccaatacc
    17041 aagccatttc atcctagttt tcatattgac cttgacaact tgttttcgtt gaccatacat
    17101 ccataaaaaa gaaatgagcg acgcacaata gagaatctgt agtatggtta actcactaat
    17161 acaaagcaat ttcagtaagt atagggatac caata
//
LOCUS       DAVHTH010000043        16980 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.043, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000043 DAVHTH010000000
VERSION     DAVHTH010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16980)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16980)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16980
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.043"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            307..1353
                     /gene="pheS"
                     /locus_tag="VVR63_001518"
     CDS             307..1353
                     /gene="pheS"
                     /locus_tag="VVR63_001518"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HEU6129525.1"
                     /translation="MSTIEEQLKALREETLASLKQITAGNEKEMQDLRVSVLGKKGSL
                     TEILKGMKDVSAEMRPIIGKHVNEARDILTAAFEETAKLLEEKKVAAQLASESIDVTL
                     PGRPVATGHRHVLTQTSEEIEDIFIGMGYQVVDGFEVEQDYYNFERMNLPKDHPARDM
                     QDTFYITEEILLRTHTSPVQARAMDAHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQ
                     IEGLVVGKNISMADLQGTLQLIVQKMFGEERQIRLRPSYFPFTEPSVEVDVSCFKCGG
                     EGCNVCKKTGWIEIMGAGMVHPRVLEMSGIDATVYSGFAFGLGQERVAMLRYGINDIR
                     GFYQGDVRFSEQFK"
     gene            1353..1862
                     /locus_tag="VVR63_001519"
     CDS             1353..1862
                     /locus_tag="VVR63_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6129526.1"
                     /translation="MIRKVEMADVEVLAKIAKQTFRETFAYDNTEEQLQEYFEEAYSL
                     KTLSTELGNPDSEAYFIMHEEEIAGFLKVNWGSAQTERELEDAFEIQRLYVLQKFQGF
                     GLGKQLFEFTLELATKNSFSWAWLGVWEHNTKAQAFYNRYGFEKFSQHHFMVGQKVDT
                     DWLLRKKLR"
     gene            1939..4344
                     /locus_tag="VVR63_001520"
     CDS             1939..4344
                     /locus_tag="VVR63_001520"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HEU6129527.1"
                     /translation="MLVSYKWLKELVDIDVPSQELAEKMSTTGIEVESVESPAADLSK
                     IVVGEVLSCEDVPETHLHVCQVNVGEEEARQIVCGAPNVRAGIKVMVALPGARIADNY
                     KIKKGKIRGLESLGMICSLGELGISDSVVPKEFADGIQILPENAVPGEEVFSYLNLDD
                     EIIELSITPNRADALSMRGVAHEVAAIYDKAVNFKEFTLTETDQVAADALSVGIETDK
                     APYYAARILDNVTIAPSPQWLQNLLMNEGIRPINNVVDVTNYILLYFGQPMHAFDLDT
                     FEGTDIRVREARDGEKLVTLDGEERDLAETDLVITVADKPVALAGVMGGQATEISEKS
                     SRVILEAAVFNGKSIRKTSGRLNLRSESSSRFEKGINVATVNEALDAAASMIAELAGA
                     TVRKGIVSAGELDTSDVEVSSTLADVNRVLGTELSYADVEDVFRRLGFGLSGNADSFT
                     VSVPRRRWDITIEADLFEEIARIYGYDRLPTSLPKDDGTAGELTVIQKLRRQVRTIAE
                     GAGLTEIITYALTTPEKAVEFTAQPSNLTELMWPMTVDRSVLRQNMISGILDTVAYNV
                     ARKNKNLALYEIGKVFEQTGNPKEELPNEINSFAFALTGLVAEKDFQTAAVPVDFFYA
                     KGILEALFTRLGLQVTYTATSEIVSLHPGRTAVISLGDQVLGFLGQVHPVTAKAYDIP
                     ETYVAELNLSAIEGALQPAVPFVEITKFPAVSRDVALLLKAEVTHQEVVDAIQAAGVK
                     RLTDIKLFDVFSGEKLGLGMKSMAYSLTFQNPEDSLTDEEVARYMEKIQASLEEKVNA
                     EVR"
     gene            complement(4412..5413)
                     /locus_tag="VVR63_001521"
     CDS             complement(4412..5413)
                     /locus_tag="VVR63_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000597989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEU6129528.1"
                     /translation="MIKTFLSALSVILFSIPIITYSFFPSSNLNIWLSTQPILAQIYA
                     FPLATATMAAILSFLFFFLSFYKKNKQIRFYSGILLLLSLILLLFGTDKTLSSASNKT
                     KTLKLVTWNVANQIEAQHIERIFSHFDADMAIFPELATNIRGEQENQRIKLLFHQVGL
                     SMANYDIFTSPPTNSGIAPVTVIVKKSYGFYTEAKTFHTTRFGTIVLHSRKQNIPDII
                     ALHTAPPLPGLMEIWKQDLNIIHNQLASKYPKAIIAGDFNATMRHGALAKISSHRDAL
                     NALPPFERGTWNSQSPKLFNATIDHILLPKNHYYVKDLDIVSFQNSDHRCIFTEITF"
     gene            5569..6015
                     /locus_tag="VVR63_001522"
                     /pseudo
     CDS             5569..6015
                     /locus_tag="VVR63_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            6141..6407
                     /locus_tag="VVR63_001523"
     CDS             6141..6407
                     /locus_tag="VVR63_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU6129529.1"
                     /translation="MEGCPSELFSKEEILESDMRVAIMSELIEARYEQGISQKKLEEV
                     SGISQPVIARMETGESSLQLDTVLKVLTSLGKTLAVVPLEQGKS"
     gene            6668..8917
                     /gene="metE"
                     /locus_tag="VVR63_001524"
     CDS             6668..8917
                     /gene="metE"
                     /locus_tag="VVR63_001524"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HEU6129530.1"
                     /translation="MSTTIIGFPRLGEFRELKFTTEKYFRKEISEEELLAAAKDLRAK
                     HWNIVKEKGITEIPSNDFSHYDNFLDAAFLFNVVPASVQNLDLSDLERYFALGRGYQG
                     EKGDVRALPMKKWFNTNYHYIVPKFEKDTQVKLAGHKIFDEFQEAKELGLNTRPVLVG
                     PFTFLQLSDFEEGVKADDFVDSLVVAYQEVFAKLAELGATRIQLDEAALVKDLTAEEK
                     ALFLNLYNKLLADKKGLEVLLQTYFGDVRDVYADLVNLPVDAIGLDFVEGKKTLELVK
                     GGFPADKTLYVGIVNGKNIWRNNYEKSLAVLEQIPAENIVLTSSCSLLHVPFTTANEE
                     FEPALLNHFAFAVEKLDEIRDLDAIRNGQGSEALAANKELFATERVGENAELRARIAG
                     LTDADYTRLPAFAEREAIQEEAFKLPALPTTTIGSFPQTKEVRAKRLAYRKGELSQKE
                     YDAFLAETIDEWIKWQEDIDFDVLVHGEFERNDMVEYFGQNLSGYLFSKNGWVQSYGM
                     RGVKPPIIWGDVTRLNSITVKWSSYAQSRTNKPVKGMLTGPVTILNWSFPREDISIKD
                     STLQIALAIKDEVLDLEAAGVKIIQIDEAALREKLPLRRSDWYEDYLDWAIPAFRLVH
                     STVAPDTQIHTHMCYSEFTDIIPAIDNMDADVISFEASRSNLEILDELKAKNFQTEVG
                     PGVYDIHSPRVPNEGEIDNTIEAILAKVPSKKVWINPDCGLKTRGIPETKESLIRLVE
                     AAKAAREKL"
     gene            8981..9847
                     /gene="metF"
                     /locus_tag="VVR63_001525"
     CDS             8981..9847
                     /gene="metF"
                     /locus_tag="VVR63_001525"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000089969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="HEU6129531.1"
                     /translation="MSRQTPSLSFEVFPPNPAVGNGNIISALQDMQELAPHFISVTAS
                     NNKFNIKETTVRLADFIQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALR
                     GDIIPDVEPQKDFRYATDLIEFIKEQAPHFDIIGACYPEGHPDSPNQISDIQNLKKKV
                     DAGCSSLVTQLFFDNERFYDFQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIH
                     LPRKFKAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQ
                     ATHALFNHQSLG"
     gene            10532..12745
                     /gene="pnp"
                     /locus_tag="VVR63_001526"
     CDS             10532..12745
                     /gene="pnp"
                     /locus_tag="VVR63_001526"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HEU6129532.1"
                     /translation="MAKQVFQTTFAGRELIVETGQVAKQANGSVVVRYGESTVLTAAV
                     MSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFDGPIAGVQVGYVDGQII
                     INPSQEQAEQSLLELTVAGTKHAINMVESGAKELSEEIMLEALLKGHEAVKELIAFQE
                     EIVAAVGKEKAEVELLHVDAELQAEIIAAYNSDLQKAVQVEEKLAREAATQAVKDQVT
                     AVYEEKYANHEEFDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRKVDEIRPLDAVV
                     DFLPRVHGSGLFTRGQTQALSVLTLAPMGETQIIDGLDPEYKKRFMHHYNFPQYSVGE
                     TGRYGAPGRREIGHGALGERALAQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMTGGVPIKAPVAGIAMGLISDGNNYTVLTDIQGLEDHFGDMDFKVAGTRDGITAL
                     QMDIKIQGITAEILTEALAQAKKARFEILDVIEATIPEVRPELAPTAPKIDTIKIDVD
                     KIKIVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAKEIIAGLVREAKV
                     DEVYRAKVVRIEKFGAFVNLFDNTDALVHISEMAWTRTNRVEDLVEIGDEVDVKVIKI
                     DEKGRIDASMKALLPRPPKPEHDEKGEKSERPHRPRHHKDHKPKKEFTETPKDSE"
     gene            12761..13378
                     /gene="cysE"
                     /locus_tag="VVR63_001527"
     CDS             12761..13378
                     /gene="cysE"
                     /locus_tag="VVR63_001527"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000539958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HEU6129533.1"
                     /translation="MGWWHETIDIVKENDPAARTTLEVLLTYPGVKALAAHRLSHFLW
                     KYDFKLLARMHSQFWRFWTQIEIHPGAQIDSGVFIDHGSGLVIGETAIVEKGVLLYHG
                     VTLGGTGKDCGKRHPTVRKGALISAHAQVIGPVEIGENAKVGAAAVVVADVPSDVTVV
                     GIPAKIVRLHGKKDEPVIHEVEEKREYYVNKLEQAKDASHRSSGL"
     gene            13390..14274
                     /locus_tag="VVR63_001528"
     CDS             13390..14274
                     /locus_tag="VVR63_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6129534.1"
                     /translation="MIQARNKLSQEELSEAKKVINCCQNYDGTYRDPYLSNMLNFDPN
                     MPAFFLYYEKGKLVGLLTVYADDQDVEVTILVHPGHRRQGIARALFTSFERETASFPI
                     RSVTFQTERIFLENHPDFASNWGLIEDEETETWLGKDRRPYPLANVSHLEVLLADSSY
                     QDQISQLKFQAFSEEHESREVVDRYVAEALKDPESRLYILLKDGQVIGTCTVDLSTNT
                     NYFYGLAISEPERGKGYGSYLAKSLVNQLIEQNDKEFQIAVEDSNVGAKRLYEKIGFV
                     KQTQVVYLNEKGARDSEV"
     gene            14361..15704
                     /locus_tag="VVR63_001529"
     CDS             14361..15704
                     /locus_tag="VVR63_001529"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002916477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HEU6129535.1"
                     /translation="MIKIYDTMSRDLREFVPIEDGKIKMYVCGPTVYNYIHVGNARST
                     VAFDTIRRYFEYRGYKVAYISNFTDVDDKIINRAREEGITPQEVADKYIAAFREDVTA
                     LGVKPATRHPRVVEFMADIIRFVEDLIEKGFAYESQGDVYFRVEKSHNYAKLANKTLE
                     DLELGASGRTDEETARKENPVDFALWKSSKPGEISWDSPWGPGRPGWHIECSVMSTEI
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKAFANYWMHNGFVNIDNVKMSKSLGNF
                     ITVHDALKTLDGQVLRFFFATQHYRKPINFTEKAVRDAETNLKYLKNTYEQPFTGNVD
                     AQELQNFKDKFVAAMDEDFNAANGITVVFEMAKWINSGNYDASVKQALADMLEIFGIV
                     FVEEVLDAEIEDLIQKRQEARANRDFETADQIRDQLVTQGIKLLDTKDGVRWTRD"
     gene            15697..16083
                     /locus_tag="VVR63_001530"
     CDS             15697..16083
                     /locus_tag="VVR63_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HEU6129536.1"
                     /translation="MIDVNLINGIALAFEGDAVYSMYIRRHLILKGMTKPNKLHQEAT
                     KYVSAKAQARLIALMLEEQILTEKEEEIYKRGRNTNSHTKAKNADVVTYRMSTGFEAV
                     MGYLHMTENLERLESLVSWCIQKVEG"
     gene            16087..16971
                     /locus_tag="VVR63_001531"
     CDS             16087..16971
                     /locus_tag="VVR63_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HEU6129537.1"
                     /translation="MRAKELQDWFPEARISDQPVEKEGYLTLPLASQQWILLEEAGLS
                     EREKQLVALLTQQEQARSLNPWYSYLVEGKGQAPQVFKKIQLVYCHLSYFQQENLTSW
                     LDMMRTLFPNCQTVLQVGAQDYVFVLQQDKYTSVRDILSDTIEAVEYDFGLRLSIMLG
                     QVWSQTGHQALSDLIKAERDLFKTWWRQGHQGVHTFSQLYLWSMGERLVDLKPIKECL
                     HQMILDQDQIQEIILSLWENSAVLTKTAQQLYLHRNSLQYKIDKWEELTGLQLKELTD
                     LTLCYQLILGSLSTIVGL"
BASE COUNT         5048 a         3314 c         3881 g         4737 t
ORIGIN      
        1 agttagataa gaataagcta acaagcagaa gtaagatagg tcttgcaaga atggtaaaaa
       61 tctgataaac taagtagtaa ttgaatagga atctgaaaga ctagtagccc aagggaagta
      121 tatcagggag gagagccgtg actgcaagct ctctatatga aagctgggtg aattcacttg
      181 cgcatggatt tagaaatgaa ggtctgactt gtcagatgaa aacggatggt accgcgtgtc
      241 aacgctccga gtggagtttt tggcatgtgg ttttcttttt atctacgaga gactgatgga
      301 ggaaatatgt caactattga agaacaatta aaagcgcttc gcgaagaaac gctggctagc
      361 ttgaagcaga ttactgctgg aaatgaaaaa gagatgcaag atttgcgtgt ctctgtcctt
      421 ggtaaaaagg gttcgctcac tgaaatcctc aaagggatga aagatgtttc tgctgagatg
      481 cgtccaatca ttgggaaaca cgtcaatgaa gctcgtgata tcttgacagc tgcttttgaa
      541 gaaacagcta agctcttgga agaaaagaaa gtcgcggctc aactggctag cgagagtatc
      601 gatgtgacgc ttccaggtcg tccagttgcg actggtcacc gtcacgtttt gacacaaacc
      661 agtgaagaaa tcgaagatat cttcatcggt atgggttatc aagtcgtgga tggttttgaa
      721 gtggagcaag actactataa ctttgaacgt atgaaccttc caaaagacca cccagctcgt
      781 gatatgcagg atactttcta tatcactgaa gaaatcttgc tccgtaccca cacgtctcca
      841 gttcaggcgc gcgctatgga tgcccatgat ttttctaaag gtcctttgaa gatgatctcg
      901 ccagggcgtg tcttccgtcg cgatacggac gatgcgaccc acagtcatca attccaccaa
      961 atcgaaggct tggtagttgg gaaaaatatc tctatggctg atcttcaagg aacgcttcag
     1021 ttgattgtcc aaaaaatgtt tggtgaagag cgtcaaattc gtttgcgtcc atcttacttt
     1081 ccattcacag agccatctgt tgaggtggat gtttcttgct tcaaatgtgg tggagaaggc
     1141 tgtaacgtat gtaagaaaac aggttggatc gaaattatgg gggccggtat ggttcaccca
     1201 cgtgtccttg aaatgagtgg tatcgatgcg actgtatact ctggctttgc ctttggtctt
     1261 ggacaagagc gtgtagctat gctccgttat ggaatcaacg atatccgtgg attctaccaa
     1321 ggagatgtcc gcttctcaga acagtttaaa taatgattag aaaagtagaa atggcagatg
     1381 ttgaggtgtt ggctaaaatt gccaaacaaa cctttcgtga aacctttgcg tatgataata
     1441 cggaagagca gttacaggaa tactttgaag aggcttatag tctgaaaact ttgtcaactg
     1501 agttgggaaa tcctgactct gaagcctatt tcattatgca tgaggaggag atagctggtt
     1561 ttctcaaagt caactgggga agtgctcaaa ctgagagaga attagaggac gcttttgaaa
     1621 ttcaacgcct ctatgtgcta caaaaattcc aaggatttgg actaggtaag caactgtttg
     1681 aattcacact tgaacttgct acaaaaaata gtttttcttg ggcttggtta ggtgtttggg
     1741 agcataatac aaaagctcaa gccttttata atcgatatgg ttttgaaaaa tttagccaac
     1801 atcattttat ggttggtcaa aaagtagata cggattggtt actgagaaag aaattaaggt
     1861 aagaagagga ttcttctatt gaaatgatag gaaaggaaaa gaactagagt gacaactgtc
     1921 attctggaga actaaattat gcttgtatct tataaatggt taaaagaatt ggtggacatt
     1981 gatgtgccat cacaggagtt ggctgaaaaa atgtcaacca cagggatcga ggtagagagt
     2041 gtcgaatcac cagctgctga tctctcaaaa attgttgtcg gtgaggtctt gtcttgcgaa
     2101 gatgtgccag agactcacct ccatgtttgt caggttaacg ttggcgaaga agaagcccgt
     2161 cagatcgttt gtggtgcacc gaatgtgcgt gctgggatca aggttatggt ggctcttcca
     2221 ggagctcgta tcgctgacaa ttacaaaatc aaaaaaggaa aaatccgtgg cttagagtca
     2281 cttggaatga tctgttcact tggtgaattg ggtatttctg actcagttgt acctaaggaa
     2341 ttcgcagatg gtattcaaat tttgccagaa aatgccgttc caggtgagga agtcttctca
     2401 tatctaaact tggatgatga aatcatcgaa ctttctatca caccaaaccg tgcagatgcc
     2461 ctttctatgc gtggagtggc tcacgaagtg gcagccatat atgacaaggc agtcaacttt
     2521 aaagaattta ctttgacaga aacagaccaa gttgcagccg atgccctttc tgtgggcatt
     2581 gagacagaca aggcgcctta ctatgcagct cgtatcttgg acaatgtgac tatcgcacca
     2641 agtccacaat ggttgcaaaa ccttctcatg aacgaaggca tccgtcccat caataacgtt
     2701 gtagacgtga caaactacat cctgctctac tttggtcaac ctatgcatgc ttttgacttg
     2761 gacacatttg aagggactga catccgtgtg cgtgaagcgc gtgatggtga aaaattagtg
     2821 accctggacg gtgaagaacg agacttggct gagacagacc tcgtgattac agttgctgac
     2881 aaaccagtag cccttgccgg tgttatgggt ggtcaggcta cagaaatttc tgaaaaatct
     2941 agtcgtgtta tccttgaagc tgctgttttt aatggcaaat ctatccgtaa gacaagtggt
     3001 cgcctgaacc ttcgttctga gtcatcttct cgctttgaaa aaggaattaa tgtggcaaca
     3061 gttaatgaag cccttgatgc ggcagctagc atgattgcag agcttgcagg cgcgacggtg
     3121 cgtaagggta tcgtttcagc gggtgagctt gatacctctg atgtggaagt ttcttcaacc
     3181 cttgctgatg ttaaccgtgt cctcggaact gagctgtctt atgctgatgt agaagacgtc
     3241 ttccgtcgtc ttggctttgg tctttctgga aatgcagaca gctttacagt cagcgtacca
     3301 cgtcgtcgtt gggatatcac aatcgaagct gatctctttg aagaaatcgc tcgtatctat
     3361 ggatatgacc gcttgccaac cagccttcca aaagacgatg gtacagctgg tgaattgact
     3421 gtgatacaaa aactccgccg tcaagttcgt accattgctg aaggagcagg tttgacagaa
     3481 atcatcacct atgctctgac aactcctgaa aaagcagttg agttcacagc tcaaccaagt
     3541 aaccttactg aactcatgtg gccaatgact gtggatcgtt cagtcctccg tcaaaatatg
     3601 atttcaggga tccttgatac cgttgcctac aacgtggctc gtaagaataa aaacttggcc
     3661 ctttatgaga ttggaaaagt ctttgaacaa acaggtaatc caaaagaaga acttccaaat
     3721 gagatcaaca gctttgcctt tgccttgaca ggcttggttg ctgaaaaaga tttccaaaca
     3781 gcagcagttc cagttgattt cttctatgct aagggaatcc ttgaagccct atttactcgt
     3841 ttgggactcc aagtaaccta tacagcaaca tctgaaatcg ttagccttca tccaggtcgt
     3901 acagccgtga tttcactcgg tgaccaagtt cttggtttcc ttggccaagt gcatccagtc
     3961 actgccaagg cttacgatat tccagaaacg tatgtagctg agcttaacct ttcagccatc
     4021 gaaggggcgc tccaacctgc tgttccattt gtggaaatca ccaaattccc agcagtcagc
     4081 cgtgacgttg cccttctcct caaggcagaa gtgactcacc aagaagttgt agatgctatc
     4141 caagctgccg gcgtgaaacg tttgacagat atcaaactct ttgacgtctt ctcaggtgaa
     4201 aaactgggac ttggtatgaa gtcaatggct tatagcttga ccttccaaaa tccagaagac
     4261 agcttaacgg acgaagaagt cgcacgctat atggaaaaaa tccaagcgtc tctcgaagaa
     4321 aaagtcaatg cagaagtgcg ttaaacgata gtaggataca aattccccct ctagtttatg
     4381 aacattagag gggtgatttt atataaaata attaaaatgt gatttctgta aaaatacatc
     4441 tatgatcaga gttttgaaaa cttacaatgt ctaaatcttt aacatagtag tggtttttag
     4501 gcaataaaat atgatctatt gttgcattaa aaagttttgg actttggcta ttccaagttc
     4561 ctctttcaaa aggtggcagt gcatttaatg cgtccctatg agagcttatt tttgcaagtg
     4621 ctccatgacg catagttgca ttaaaatcac ctgcaataat agcctttgga tattttgaag
     4681 ccaattgatt atgaatgatg tttaagtctt gcttccagat ttccattaaa cctggcagag
     4741 gaggagcagt atgcaaggca atgatatctg gtatattttg ttttctcgaa tgtaatacaa
     4801 ttgtcccgaa ccgtgttgta tgaaaagttt tagcttctgt atagaaacca taacttttct
     4861 tgacaatcac agtcacagga gctattccac tattggtagg tggagaagtg aaaatatcat
     4921 agttggccat agaaagtcca acttgatgaa acaatagttt gattctctgg ttttcttgct
     4981 cacctctgat attggtagct agttcaggga atatagccat atcggcgtca aaatggctaa
     5041 aaattcgctc aatatgttgt gcttctattt gattagcgac gttccaagtt actaatttta
     5101 aggttttagt cttatttgat gcagaagaaa gggttttatc tgttccgaat aatagtaata
     5161 tgagcgatag taagagcaaa atgccagagt aaaaccgtat ttgtttattt ttcttgtaaa
     5221 aagataggaa aaaaaataag aaacttaaaa tagcagccat agttgcagta gctaagggga
     5281 aggcataaat ctgtgccaag ataggttggg tagatagcca aatgttaaga ttagaagatg
     5341 ggaaaaaaga ataagttata atagggatag aaaagagaat gaccgaaagg gcagagagaa
     5401 atgttttaat cattgtgtga gtacctcaat ttgcaatggt tgctcggagc taatgtgact
     5461 ttgtgacttt acttgattga tattcttttt cttgtcttcc tcatagatta agtacaaccc
     5521 aagtaaaaaa agtccaattt aagattgaaa tgattaaaag gcacagaaat gcaagacaat
     5581 tatactacaa aaggcaaaca tttgacaatc gatagccgtc gcttaatcga acgatggaaa
     5641 aaagaaggaa aatcaaatag agaaattgcc tctctacttg gaaaagctcc tcaaactatc
     5701 catactgaaa tcaagtatgg gacagtccga caatgtcttg gaaaagggcg cttcaaagag
     5761 atttattctg ccgactacgc tcaacagtct tatgaaaata atcgcaagca ctcggtcaag
     5821 aaatcaagct tgactaagaa actaaaggaa aagattctcc actatcataa ccaaaaattt
     5881 tcgcctgaaa tgatggtgat ggctaaaggg gttaacgtgg gaatttcaac catttactat
     5941 tggattcatc gtggaaaatt ggggttaagc aagcaggatc tgctttatcc tagaaaagga
     6001 aaagcgctta agaaataggc tagcaccaac tttaaacccg ctggtcaatc tatcgaatca
     6061 taattcgctc atttttttaa aaatacatag acgtaaaaaa aagagggtta agtgatgaag
     6121 aatagtgcta ttgggagtaa ttggaaggat gtccatctga gctctttagc aaggaggaaa
     6181 tccttgaaag tgatatgcga gtggctatca tgagcgagtt gattgaggct aggtatgaac
     6241 aaggaatcag tcagaaaaag ctggaagaag tcagtggaat aagccagcct gtcatagcta
     6301 ggatggagac aggagagagc agtcttcagt tggatacggt cttaaaagtt ctaaccagtc
     6361 taggaaagac actagcagtc gttccacttg aacaggggaa aagttgacta gaatcagtta
     6421 tagtcttttc taataacagg tcatagtcac ttataagaat tactaataac atgttttagt
     6481 attctaattg gaatatagct gtaaagtaag aattacaaag gatttgagac gtttgcttca
     6541 agtctttttc ttttgtccga aacagatata tagtttcaaa ctatatcaaa ccctaatttt
     6601 ttacaattat acagacgctt tcttttctgt taagatagtt tcaacaacaa attttggagg
     6661 acacatcatg tcaactacaa tcatcggttt ccctcgtttg ggcgaattcc gtgaattaaa
     6721 atttacaact gaaaaatact ttagaaaaga aatctcagaa gaagaacttt tagcagcagc
     6781 aaaagacttg cgtgctaaac actggaacat tgtcaaagaa aaaggcatca ctgaaattcc
     6841 atcaaatgac ttttctcact atgataactt cctagatgcg gctttccttt tcaacgtggt
     6901 gcctgcatcc gttcaaaact tggacttgtc tgaccttgag cgctacttcg ctttgggacg
     6961 tggttaccag ggagaaaaag gggacgttcg cgcccttcca atgaagaaat ggttcaacac
     7021 taactaccac tacatcgttc ctaaatttga aaaagacact caagtaaaat tggctggtca
     7081 caagattttc gatgagttcc aagaagcaaa agaacttgga ttgaacactc gtcctgttct
     7141 tgtaggtcca ttcactttcc ttcaattgtc agactttgaa gaaggcgtga aagcagacga
     7201 cttcgtagat agcttagtgg ttgcttacca agaagttttt gctaaattgg ctgaacttgg
     7261 tgcgactcgc atccaattgg atgaagcggc tcttgtaaaa gacttgacag ctgaagaaaa
     7321 agctctcttc ttgaaccttt acaacaaact cttggctgac aaaaaaggtc ttgaagtctt
     7381 gcttcaaact tatttcggtg atgttcgtga cgtatacgct gaccttgtaa acttgccagt
     7441 agatgctatc ggtcttgact ttgttgaagg taagaaaact cttgaactcg ttaaaggtgg
     7501 cttcccagct gacaagactc tctatgtagg tattgtcaat ggtaaaaaca tctggcgcaa
     7561 caactacgaa aagagcttgg ctgttcttga gcaaatccca gctgaaaaca tcgttttgac
     7621 aagctcttgc tcacttcttc atgtgccatt tacaactgct aatgaagaat ttgaaccagc
     7681 actcttgaac cactttgcct ttgcagttga aaaattggat gaaatccgtg acttggatgc
     7741 tatccgcaat ggtcaaggtt cagaagctct tgcagccaac aaagaactct ttgcgactga
     7801 gcgtgttggt gaaaatgctg aacttcgtgc gcgtatcgct ggcttgacag acgcagacta
     7861 cactcgtttg ccagcctttg cagaacgtga agctatccaa gaagaagctt tcaaacttcc
     7921 agctcttcca acaacaacga ttggttcatt ccctcaaaca aaagaagttc gtgccaaacg
     7981 tttggcttac cgtaaaggtg aattgtctca aaaagagtac gatgctttcc ttgctgaaac
     8041 gattgacgaa tggatcaagt ggcaagaaga tattgacttt gatgtccttg ttcacggtga
     8101 atttgagcgt aatgacatgg ttgagtactt cggtcaaaac ttgtcaggat acctcttctc
     8161 taaaaatgga tgggtacaat catacggtat gcgtggggta aaaccaccaa tcatctgggg
     8221 tgatgtcact cgtcttaact ctatcactgt taaatggtct agctatgcac aaagtcgtac
     8281 aaacaaacct gttaaaggta tgttgactgg acctgttacc atccttaact ggtcattccc
     8341 acgtgaagac atctctatca aggattcaac tcttcaaatc gcccttgcta tcaaggatga
     8401 agtacttgac cttgaagctg ctggtgtgaa aatcatccaa atcgacgagg ctgctcttcg
     8461 tgaaaaattg ccactccgcc gtagcgactg gtacgaagac taccttgact gggctattcc
     8521 tgccttccgc ttggtacact caacagtagc gccagacaca caaatccaca ctcacatgtg
     8581 ttactcagaa tttacagata tcatcccagc tatcgataac atggatgcag acgttatttc
     8641 ctttgaagct agccgttcaa accttgaaat cttggacgaa ctcaaagcga aaaacttcca
     8701 aacagaagtg ggacctgggg tttacgatat ccactcacct cgtgtaccaa atgaaggcga
     8761 aatcgacaac acaatcgaag ccatccttgc taaagtgcca agcaagaaag tttggatcaa
     8821 ccctgactgt ggtttgaaaa cacgtggtat cccagaaaca aaagaaagct tgatccgcct
     8881 tgttgaagca gctaaagctg cgcgtgagaa attgtaagat tggatttctc tccatacagt
     8941 ggttgttcaa aaagaaatca actagaaaag gttattacat atgtcacgcc aaacaccgtc
     9001 actctcattt gaagtgttcc ctccaaaccc agccgtgggt aatggtaaca ttatttcagc
     9061 cttgcaggat atgcaggagt tggctcccca ttttatcagt gtaactgcca gcaataataa
     9121 atttaatatc aaggaaacga cggttcgttt ggctgacttt atccaaaatg acttggcgat
     9181 tccgaccatt gcccacttgc cagctattta tctaactaag gacaaggttg ctgaaactat
     9241 tgctgacttg gacaaagttg gggtgcagaa aatcttggct cttcgtgggg atattattcc
     9301 agacgtagaa ccacaaaagg atttccgcta tgcaaccgac ttgattgagt ttatcaagga
     9361 acaagcccct cactttgata ttattggagc ttgctatcca gaagggcatc cagattcgcc
     9421 aaatcagatt tcagatattc aaaatcttaa gaagaaagtg gatgcaggct gttcgagcct
     9481 cgtaactcag ctcttctttg ataatgagcg cttctatgat tttcaggaca agtgtatttt
     9541 ggctgggatt gatgttccca ttcatgcagg aattatgcca attctgaatc gaaatcaggc
     9601 tctccgactc ttgaagactt gtgagaatat ccatcttcca cgcaaattta aagccatctt
     9661 agacaagtat gagcatgacc ctgagtcgct cagagcagca ggacttgcct atgcagtgga
     9721 ccaaatcgtg gacttggtaa ctcaggatgt tgccggtgtg catctctata cgatgaataa
     9781 tgctgataca gcaaaataca tccatcaagc aacccatgcc ttgtttaatc accagtctct
     9841 aggataataa aagcaaacca ttcttctcag gtgaggggaa tggttccttt ttaatggtaa
     9901 agacctcact ttttaagaaa aatatgataa aataaattct gtacgtactt gatacaaaga
     9961 tgaaggtatt aaataataca atgcatttaa actgtaagat ttaacgacac gagtgagtca
    10021 aatcgatgtt atttgacgag agagttagta aagcatttag ctaatcgccc gatagcgatt
    10081 agcgtgaaag ctttagatac tttagtatta aacctttcta atgatgtatc ttgaaaactg
    10141 aacttgccta caactctgtg gaaaaagata aatctcccta ggagcagtcg ctccgtcgtt
    10201 cgatttccta ttttcctttg agttgcttga cggcttggta tcttgatgac ttgaattttg
    10261 gtctcatttc ttaggaaaaa agataagctt cctagcactc gtcgagtgcg acgtcacctt
    10321 cctatttttc tacagaaatg ttcggcaagc cgaaccgtcc aaaatatctt gtgtaattga
    10381 acacggccga aaagctgtgt aaaaaagata aactgtcttg tcttcatcga agacttcgtc
    10441 agtttcctat ttttactttg cttttgacgt ccttggtatc ttgatctttg taggcaaggc
    10501 gtataatttc atcaatccaa aggggattaa aatggcaaaa caagtgtttc aaacgacttt
    10561 tgcgggtcgt gagttaattg tagaaactgg tcaggttgct aagcaagcaa atggctctgt
    10621 tgtcgtacgt tacggtgagt caactgtctt gactgctgcc gttatgtcta agaaaatggc
    10681 aactggggat ttcttcccac tccaagtcaa ctacgaagaa aaaatgtatg cggctgggaa
    10741 gtttcctggt ggctttatga aacgtgaagg acgtccttca acagatgcga ccttgacagc
    10801 gcgtttgatt gaccgtccga ttcgtcctat gtttgcggaa ggtttccgta atgaagtcca
    10861 agtcatcaat acagtgcttt cttatgatga aaatgcatct gcaccaatgg ctgctatgtt
    10921 tggttcatct ttggcactgt ctatttcaga tattccattt gacggaccaa ttgctggggt
    10981 acaagtggga tatgtagatg gccaaatcat catcaaccca agtcaagaac aagcagagca
    11041 atctcttctt gaattgacag tagctggaac caagcacgct atcaacatgg tagagtctgg
    11101 tgccaaagaa ttgtcagaag aaatcatgtt ggaagcgctt cttaaagggc acgaagctgt
    11161 caaagaattg attgccttcc aagaagaaat cgttgctgct gtcggtaaag aaaaagcaga
    11221 agtggaattg cttcacgtgg atgctgaatt gcaagctgaa atcattgcag cctacaacag
    11281 tgacctccaa aaggcagttc aagtagaaga gaaattggcc cgtgaagctg caactcaagc
    11341 agtgaaagac caagtgactg ccgtttacga agaaaaatat gcgaaccacg aagaatttga
    11401 ccgtattatg cgtgatgtgg ctgaaatctt ggaacaaatg gaacacgcag aagtgcgacg
    11461 tttaattaca gaagacaagg tgcgtcctga tggtcgtaag gtcgatgaaa tccgtccttt
    11521 ggatgcggtt gttgacttcc ttcctcgtgt acatggttca ggtctcttta ctcgtgggca
    11581 aactcaagct ctttcagtct tgaccttggc tccgatggga gaaactcaaa tcattgatgg
    11641 tttggatcca gagtacaaga aacgctttat gcaccactat aacttccctc aatattctgt
    11701 aggggaaaca ggtcgttacg gtgcgccagg tcgtcgtgaa atcggtcacg gtgcccttgg
    11761 tgagcgtgct cttgctcaag tcttgccaag cttggaagaa ttcccatacg ctatccgtct
    11821 agtagcagaa gttttggaat caaacggttc ttcatctcaa gcttctatct gtgcgggaac
    11881 tcttgccctt atgactggtg gtgtgccaat caaggcgcca gtagctggta ttgctatggg
    11941 acttatctca gatggaaata actacacagt attgacagat atccaaggtt tggaagatca
    12001 ctttggagat atggacttca aggttgcagg tactcgtgat gggattacag cccttcaaat
    12061 ggatatcaag attcaaggga ttactgcaga aatcttgacg gaggctcttg ctcaagccaa
    12121 gaaagcgcgt tttgaaatcc ttgatgtcat tgaagcaacc attccagaag ttcgtccaga
    12181 attggctcca actgctccga aaattgatac gatcaagatt gatgtggaca agattaagat
    12241 tgtcatcggt aagggtggag aaaccatcga caagattatc gctgaaacag gtgttaagat
    12301 tgatatagac gaagaaggaa atgtgtctat ctactctagt gaccaagatg ctattaaccg
    12361 tgccaaagaa attattgctg gtttggttcg tgaagccaaa gtggatgaag tttaccgtgc
    12421 taaagtcgtt cgtatcgaga aatttggtgc ctttgttaac ctctttgata atacagatgc
    12481 ccttgttcat atctctgaga tggcttggac tcgtaccaat cgtgtagagg atttggtaga
    12541 aatcggggat gaagttgatg ttaaggttat caagattgat gaaaaaggcc gtatcgatgc
    12601 ctctatgaag gctcttctac ctcgtccgcc aaaacctgag catgatgaaa aaggtgaaaa
    12661 gtctgagcgc cctcaccgcc cacgtcatca caaggatcac aaacctaaga aagaatttac
    12721 agaaacacca aaagattcag agtaagaaaa ggagaaatgt atggggtggt ggcacgaaac
    12781 cattgatatc gtaaaagaaa atgatccagc ggcccgcacc actttggagg ttttgctgac
    12841 ttatccaggt gtcaaggcct tggcggccca ccgtctctcg cattttctct ggaagtacga
    12901 cttcaaactc ttagctcgta tgcacagtca gttttggcgc ttttggactc agattgagat
    12961 tcatccagga gcccagattg attcaggtgt ctttattgac catggttctg gtctggtgat
    13021 tggagagaca gcgattgttg aaaaaggcgt tcttctctat cacggagtga ctctcggggg
    13081 aacagggaaa gactgtggca aacgccatcc gactgtacga aagggagccc tcatatcagc
    13141 ccatgcccaa gttatcgggc ctgtggaaat tggtgaaaat gccaaggtcg gtgctgcagc
    13201 agttgtcgta gcagatgtac ctagtgatgt gacggttgtc ggtattccgg ccaagattgt
    13261 ccgtcttcat ggtaagaaag atgagcctgt tattcacgaa gtcgaagaaa aacgggagta
    13321 ttatgtcaat aaactcgagc aggctaaaga tgccagtcac agatcgtctg gtttgtagag
    13381 gatacctata tgattcaagc aagaaacaag ttaagccaag aggagctatc tgaggcgaaa
    13441 aaagtaatta actgttgcca aaactatgac ggtacctatc gcgatcccta tctctctaac
    13501 atgcttaatt ttgacccaaa catgcccgcc tttttccttt attatgaaaa aggcaaactt
    13561 gttggtttat taactgtcta tgcagatgac caagatgtag aagtgacgat attggttcat
    13621 ccaggtcatc gccgtcaggg gattgcgcgt gcattgttta ctagttttga gagagaaaca
    13681 gcttctttcc ccattcggtc agtcactttt cagacagaac gtattttttt agagaatcat
    13741 cctgactttg ccagtaactg gggactaatc gaggatgaag agacagaaac ttggttaggt
    13801 aaggatagaa gaccttatcc gttagcaaat gtttcccatc ttgaagtttt gttagcagat
    13861 agttcgtatc aggatcaaat tagtcaatta aaatttcagg cattttcaga ggaacatgaa
    13921 tcgagagaag ttgtggatag atatgtcgct gaagctctga aggatccaga aagtcgctta
    13981 tatattttgt taaaagacgg tcaggttatt gggacttgca cggtagattt atcgactaat
    14041 acgaattact tctacggttt agcaatatcg gaacctgaac gtgggaaagg ctatggaagc
    14101 tacttagcaa aatccctcgt caaccaacta attgagcaaa atgacaagga atttcagatt
    14161 gcagtggaag atagcaatgt aggtgccaaa cgtttgtatg aaaaaattgg ctttgtcaaa
    14221 cagacacagg tggtttatct gaatgagaaa ggagcaaggg attccgaagt gtagagacat
    14281 tcggactgaa atttacttga gctcttagtt tagtgatgaa actaacagtt cttggatttt
    14341 agctttcctg attatgattt atgattaaaa tctatgacac catgtctcgt gatttgcgag
    14401 aatttgtccc gattgaggac ggcaagatca agatgtatgt ttgtgggcca accgtgtaca
    14461 actatattca cgtgggaaac gcccgttcga cggtagcttt tgatacgatt cgtcgctatt
    14521 ttgagtaccg tgggtataag gttgcctata tttccaattt tacagatgtg gatgataaga
    14581 ttatcaaccg tgccagggaa gaaggcatca cacctcagga ggttgcggat aagtacatcg
    14641 ctgcctttcg tgaggatgtg acggccttag gcgtgaaacc tgcgactcgc catccgcgtg
    14701 tagtggagtt tatggcagac atcatccgtt ttgtggaaga cttgatcgag aaaggctttg
    14761 cctatgagag tcaaggggat gtctatttcc gtgtagaaaa atcccacaac tatgctaaat
    14821 tggctaataa aaccttggaa gatttggagc taggtgcttc aggtcgtacc gatgaagaaa
    14881 cggctcgtaa ggaaaatcct gtagactttg ctctatggaa atcttccaaa ccaggtgaga
    14941 tttcttggga tagtccttgg ggacctggac gtccgggttg gcatattgag tgttcagtca
    15001 tgtcgacaga gattttaggt gataccattg atatccacgg tggtggagct gacctagagt
    15061 ttccacacca caccaatgaa attgcccaat ctgaagctaa aacaggcaag gcttttgcta
    15121 actactggat gcacaatggc tttgtcaata tcgacaatgt caaaatgtct aagtccttgg
    15181 gtaacttcat tacggtacac gatgccctta aaactcttga tgggcaagta cttcgtttct
    15241 tctttgcgac ccagcactac cgtaagccta tcaacttcac ggaaaaggca gttcgcgatg
    15301 ccgagaccaa tctcaagtat ctgaagaata cttacgaaca accatttaca ggaaacgtgg
    15361 atgcccaaga gttacaaaac tttaaagata agtttgtagc agctatggat gaagatttta
    15421 atgctgccaa cggtatcaca gttgtctttg aaatggccaa atggatcaac tcagggaact
    15481 atgatgcaag tgtcaagcaa gctcttgcag atatgttaga aatttttgga attgtctttg
    15541 ttgaggaagt tttggatgca gagattgaag acttgattca aaaacgccaa gaggcgcgtg
    15601 ccaatcgtga ctttgagaca gcagaccaaa tccgtgacca attggttact caaggaatta
    15661 agctccttga taccaaggat ggagtgaggt ggacacgtga ttgatgtcaa tctcattaac
    15721 gggattgcgc tagcctttga gggagatgcg gtgtattcta tgtatattcg ccgccacctc
    15781 atcctcaaag gtatgaccaa gcccaataaa ctccaccaag aggcgaccaa gtacgtgtca
    15841 gccaaggctc aggctcgtct gattgctctc atgttggagg agcagatcct aacggaaaaa
    15901 gaagaagaaa tctacaaacg tggccgcaat accaatagtc acacaaaggc taaaaatgca
    15961 gatgtcgtga cttatcgtat gtccacggga tttgaagcag ttatgggcta tctccatatg
    16021 actgagaatc tggaacgtct tgagagtttg gtttcatggt gcatccaaaa agtggagggc
    16081 tagaacatga gggcaaaaga actacaagac tggtttcctg aggctcggat ttcagaccaa
    16141 ccagtagaga aagagggcta tctcacgctt cctttagctt ctcagcagtg gattttgctg
    16201 gaggaagctg ggctcagcga gcgtgaaaag cagttggttg cccttttgac ccagcaggag
    16261 caggctcgtt cgctaaaccc ttggtattcc tatctggttg agggcaaggg acaggcaccg
    16321 caagttttta aaaagattca gttggtttat tgccatcttt cttattttca gcaggaaaat
    16381 ctgacttctt ggctagatat gatgcggact ctttttccga attgtcagac agtgctacag
    16441 gtcggagctc aggattatgt tttcgtgctt caacaagaca aatacacttc tgtaagagat
    16501 attttgagtg atacgattga agcggttgag tatgactttg gacttcgtct ttctatcatg
    16561 ttgggtcagg tttggtctca gacaggacat caagccctat cagacttaat caaagctgag
    16621 cgggatttgt tcaagacatg gtggcgtcag ggtcaccaag gtgttcatac tttttctcag
    16681 ctctatcttt ggagtatggg agaaagactc gtggacttga agccaattaa agaatgtcta
    16741 caccagatga ttttggatca agatcagatt caggaaatca ttctctctct ttgggaaaat
    16801 agtgctgttc tcactaaaac agcccagcaa ctctatctgc accgcaattc tctccaatac
    16861 aagattgata aatgggaaga gttgacaggg cttcagttga aagagttgac cgacctgacc
    16921 ttgtgttatc aattgatttt aggttctttg tcaactatag ttggtttgta aagaagttaa
//
LOCUS       DAVHTH010000044        16704 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.044, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000044 DAVHTH010000000
VERSION     DAVHTH010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16704)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16704)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16704
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.044"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            59..1237
                     /locus_tag="VVR63_001532"
     CDS             59..1237
                     /locus_tag="VVR63_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6129538.1"
                     /translation="MTLPVRKSLHDAVLQASKADTWEQATKEWNEVSLIFNGIGRSNC
                     VCGNAIKYAYELFNGVTGQRLFPIGSDCVRHFHRLSLDQQLEEEEKLLRKVENLTRKA
                     QKKEKIKVNKSDFDERLLKWLWEKGVFKPNRGNQFAPERDYQLFLEVFQGGSWTKAEP
                     KKKARMEEVLEKCIKPFLLGKSDDQLYLVKLGKEKIDYEQELRIQAEKERKKRDKIAK
                     QYADNLVLAMGPAERAYQDYFGFTETLTQEERKWEKILFGKNRAERAIKAKQYQKELE
                     KDQRIASQDPIERKQKQTWLLNSYFRELPEEKARFSRLLLEYRKSGEVPFSTEYLSDH
                     LIDFFYKMKAFEFEIAPEQVRDFLKKSLQEDHRSSAQGSWIEGILLNCLKPFLERLVI
                     "
     gene            1446..7925
                     /locus_tag="VVR63_001533"
     CDS             1446..7925
                     /locus_tag="VVR63_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEU6129539.1"
                     /translation="MEKYFGEKQERFSFRKLSVGLVSATISSLFFMSVLASSSVDAQE
                     TAGVHYKYVADSELSSEEKKQLVYDIPTYVENDDETYYLVYKLNSQNQLAELPNTGSK
                     NERQALVAGASLAALGILIFAVSKKKVKNKTVLHLVLVAGMGNGVLVSVHALENHLLL
                     NYNTDYELTSGEKLPIPKEISGYTYIGYIKEGKTTSDFEVSNQEKSAATPTKQQKVDY
                     NVTPNFVDHPSTVQAIQEQTPVSSTKPTEVQVVEKPFSTELINPRKEEKQSSDSQEQL
                     AEHKNLETKKEEKISPKEKTGVNTLNPQDEVLSGQLNKPELLYRDETIETKIDFQEEI
                     QENPDLAEGTVRVKQEGALGKKVEIVRIFSVNNEEVSREIISTSTTAPVSRIVEKGTK
                     KAQVIKEQAETGAEHKEVQSGAIVEPAIQPELPAAVLTDKGESAVQPELPEAVVSDKG
                     VPEVQPALPEAVMTDKGDPEQVEPLPEYTGVQAGAIVEPEKVEPEYAGVQAGAIVEPE
                     QVAPLPEYTGVQAGAIVEPEKVEAPKEYTGVQAGAIVEPEKVEAPKEYTGVQAGAIVE
                     PEKVEPSKEYTGVQAGAIVEPEQIAPLPEYTGVQAGAIVEPEKVEALKEYTGKIEQPS
                     AEDTKPNNENTNTPEEMSIQKKSSALINMNFITDSSKVTGVGSATFIAPNVLLTVAHN
                     FINNSTDNTTGEFRGDKSKNVYEWVTPDGQKGTFTANNIHFYNKKDYPKGFIYDLAVI
                     KLPETTGREHVELVKNYSKVNLNDKLNVHGYPAGKYTHLKDATVEMEQEYANNTYGVQ
                     YQGGNPGMSGGGIFNANGEVIGVHQNGAQNRSGGLILSPTQLAWIKSIIAGNEIPPVY
                     DELYRHKDEKKDDAKDEKEVIKKLELRNISSVELYSKDGNKYRHVTSLASLPSNAENY
                     FMKVKSENFKDVMLPVTSITNDTKDNRDVYKIVASANSLIQHENNNVLENYTYYLPKT
                     QQSETGVYTSFKNLVDAMNSNPNGTFRLGATMDAREVELPDGQESYVNNVFHGILVGT
                     NNEKYYAIYNLKKPLFGELNGATVEKLSLKDVNISAKDDTATLAKEANNNTHIDNVHA
                     DGAIAGERSIGGLVSQVNNSTISNSSYTGRITNTYKTVASYQIGGLVGKLSGPRGLID
                     KSFASIDLSSNATQGDQSIGGIVGAVENSALISNSYAEGNLNNVQRFANVGGVVGNLW
                     DPVGGLEKSGRLSNVLSDVNVTNGNAIAGYNFNGIKANGTYSNKNNKVVNVVQEDDEI
                     LTKDSTVQRGEVLEDAQIKEKKATFVSKNTIKTEDFNFSSRYVTDYKNLENADSSKEK
                     VYKNIEKLLPFYNRETIVKYGNLVETSSNLYNKELLSVVPMKDKEVISDINKNKSSIN
                     KLLLYYADNTSETLNVNYQTDFSNVAEYRIGGTNLIYTPNTLLRNYQNILDEVLPALN
                     SVEYKSEAIRKVLDVSKDVSLTELYLEEQFNTTKTNLKDSLTKLLTADAAIAENNNKV
                     IDNYVIEKIKNNKEALLLGLTYLERWYDFKYRDTKAKDLVMYHLDFFGKSNSSALDNV
                     IELGKSGYNNLLAKNNVITYNVLLAKNYKTNNLFDALEKYRKAFVPDKTNNEWFKEQT
                     KAYIVEEKSTIKEVSDKQSIAGSPYSIGVYDRLTSPSWKYPSMVLPLLTLPEKSVFII
                     ANISTIGFGAYDRYRSKEHPAGTDLNDYVEKKAKEAAVRFRDHYDYWYRILDDKNKEK
                     LYRSVLVYDAFRFGTDEKEDKDTYQATFETNHPAIKHFFGPAGNNVVHNSNGAYATGD
                     AFYYMAYRMLDKDGAVTYTHEMTHNSDREIYLGGYGRRNGLGPEFYAKGLLQAPDHPN
                     NPTVTINSILKYDQSEESTRLQVADPTQRFGSVDDLNKYMHNMFDVIYMLEILEGKAV
                     AKLDTNQKYDLLRKIENEYKPDPDGNSVYATNVVRRLKPEELTKLTTFNSLIEHDIIT
                     RRGYVDEATYKRNGYYTINLFSPIYSALSSKIGTPGDLMGRRIAFELLAAKGYKDGMV
                     PYISNQYEKEAKAQGKVITSYGKQIGLVTDEIVLSKVFNNQYNSWIDFKKDMYKERED
                     KFGKLNKVSFIDPNGSWARQQKVTIDNINRLEKMIEDAVKFDAEDEVAKLYPETNSRV
                     LKLKKAIFKAYLDQTGDFRSSIFENKK"
     gene            7969..13182
                     /locus_tag="VVR63_001534"
     CDS             7969..13182
                     /locus_tag="VVR63_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000054791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEU6129540.1"
                     /translation="MSLLKKDKFSIRKIKGIVGSVFLGSLLFAPSVVGASTYHYLDYS
                     SLTQTERDQLKQGRPDESKESYALDYEKDALPNTGSSQSIMTALGLLAIGSLIVIITK
                     DNRNKKIATFLIVGATGLVTLSTASALNLNANIHESGRDGVLQISGYRYVGYLELDDK
                     TVSSVSPASTVSPVEQPKVVTEKGEPEVHEKPDYTQPIGANLVEPEVHEKLAYTEPVG
                     TTGVDENGNLIEPPVNDIPEYTEPVGTTGVDENGNLIEPPVSDIPEYTEPISTVSEVA
                     SEREELPSLHTDIRTETIPKTTIEESDPSKFIGDDSVRQVGEDGERQIVTSYEELHGK
                     KISDPVETVTILKEMKPKILVKGTKEKPKEKTAPVLTLDRTNTNVLNRSATLSYHLVN
                     TDGVTINKITATIKDGNEIVKTVDLTSEQLDKQVEDLKFYKDYKIETTMTYDRGKGEE
                     TATLEEKPLRLDLKKVEIKNIASTNLVKVNDDGTETPSDFMTEKPSDEDVKKMYLKIT
                     SRDNKVTRLAVDKIEEVTEEGKKLYKITAEAQDLIQHTDPTKVRNKYVHYIEKPVPKV
                     DDVYYNFKELVDAMNADKNGTFKIGADLNATNVPTPNKQYVPGTFKGHLSSVDGKQYT
                     IHNIARPLFDRVENGSVKNINLGNVDINMPWADGIAPVANMVKNATVEDVKVTGNVVA
                     NNNIAGIVNKIDSGGQLTNVAFIGNLTGVGDKGQYMAGIAGEIWRGNLAKAYVEADIV
                     ANRARIGGLVAKTDNGNDSMGIGKYGSIRKSVTKGTIKTKVLFETGGFINSNLPFGKL
                     EDNISMMRVENGEEFFGSSDLDYDGGYFTNGWLERNFVVKGVSSGKHSYKRSRDKIKE
                     ISQDEANKRIANFGLTADKYEINEPVVNRLNRLTRREDEYKSTQDYKSERDLAYRNIE
                     KLQPFYNKEWIVNQGNKLAEDSNLAKKEVLSVTGMKDGQFVTDLSDIDKIMVHYADGT
                     KEEMDVTKNTDSKVQQVREYSVSGLGDVVYTPNMVVKNRDKLIADVKSQLSSVELISQ
                     EVRDLMSRRDKPAENTDERKNGYIKDLYLEESFAEVKQNLDKLVKSLVENEDHQLNGD
                     EAAIKSLLKKVETNKAKIMMALTYLNRYYDIKYGDISIKNIMMFKPDFYGKTPSVIDR
                     LINIGSSEKNLKGDRTQDAYREIIAGNTGKSNLRNFLEYNMRLFTEDKDINDWFIHSA
                     KNVYVSEPKTTNTELKDKRHRVFDGLDNGVHGRMILPLLTLKDAHMFLISTYNTMAYS
                     SFEKYGKHTEEARNEFKTKIDEVAHAQQTYLDFWSRLALPNVRDRLLKSQNMVPTPVW
                     DNQTYNGSPVGRRGFDSKGNPIAPIRELYGPTWRHHDRDWRMGAMASIFPNPNNDDKV
                     LFMVTDMISPFGISAFTHETTHVNDRMLYFGGHKHRQGTDVEAYAQGMLQTPDSSTTN
                     GEYGALGINMAYHRPNDGNQWYNPDPDKLKTRDDIDRYMRNYNEAMMLLDHVEADAVL
                     PKIKGDNSKWFKKIDKEMRSKIQYNDLLGPNQWDSIRDLKDEEKVMTLSSVNDLVDNN
                     FMTKHGNPGNGRYRPEDFTPNSAYVNVNMMAGIYGGNTSQGAPGSLSFKHNAFRMWGY
                     YGYENGFISYVSNKYKAEADKNNHGLLSDKLIINKVSKGNFNTLEEWKRHWYGEVLAK
                     AKKGFEAIDIDGVHISNYDELRPLFDKAVEEDLKKPDDFSHTVALKSKVFKALLKNTD
                     GFFNKLFKEDI"
     gene            13436..14287
                     /gene="ylqF"
                     /locus_tag="VVR63_001535"
     CDS             13436..14287
                     /gene="ylqF"
                     /locus_tag="VVR63_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HEU6129541.1"
                     /translation="MATIQWFPGHMSKARRQVQENLKFVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLLILNKADLADPAMTKEWRQYFESQGIQTLAINSKEQVTVKVVTDAAK
                     KLMADKIARQKERGIQIETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
                     WLKTNKDLEILDTPGILWPKFEDETVALKLALTGAIKDQLLPMDEVTIFGINYFKEHY
                     PEKLAERFKQMKIEEEAPVIIMDMTRALGFRDDYDRFYSLFVKEVRDGKLGNYTLDTL
                     EDLDGND"
     gene            14274..15053
                     /locus_tag="VVR63_001536"
     CDS             14274..15053
                     /locus_tag="VVR63_001536"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HEU6129542.1"
                     /translation="MATIKEIKEFLVTVKELESPIFLELEKDNRSGVQKEISKRKRAI
                     QAELDENLRLESMLSYEKELYKQGLTLIVGIDEVGRGPLAGPVVAAAVILPKNCKIKG
                     LNDSKKIPKKKHLEIFQAVQDQALSIGIGIIDNQVIDQVNIYEATKLAMQEAISQLSP
                     QPEHLLIDAMKLDLPISQTSIIKGDANSLSIAAASIVAKVTRDELMKEYDQQFPGYDF
                     ATNAGYGTAKHLEGLTKLGVTPIHRTSFEPVKSLVLGKKES"
     gene            15069..16619
                     /locus_tag="VVR63_001537"
     CDS             15069..16619
                     /locus_tag="VVR63_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HEU6129543.1"
                     /translation="MEEQSEIVRSKKEFAFASSTILSQVGRGIIVGLIVGIIVGSFRF
                     LIEKGFHLIQGVYQDQGYLVRNLFVLVLFYILICWLSAKLTRSEKDIKGSGIPQVEAE
                     LKGLMSLNWWGILWKKYVLGILAIASGLMLGREGPSIQLGAVGGKGIAKWLKSSPVEE
                     RSLIASGAAAGLAAAFNAPIAALLFVVEEVYHHFSRFFWVSTLAASIVANFVSLLMFG
                     LTPVLDMPDNIPPMTLDQYWIYLVMGIFLGFSGFLYEKAVLNVGRVYDLIGQKIHLDR
                     AYYPILAFILIIPVGIFLPQIIGGGNQLVLSLTEQNFSFQVLLAYFLIRFIWSMISYG
                     SGLPGGIFLPILALGSLLGALVGVICVNLGLVSQEQFPIFVIIGMSGYFGAISKAPLT
                     AMILVTEMVGDIRNLMPLGLVTLVSYIIMDLLKGTPVYEAMLEKMLPEEVSSEGEVTL
                     IEIPVSDKIAGKQVHELNLPHNVLITTQVHNGKSQTVNGSTRMYLGDMIHLVIPKSEI
                     GKVKDLLL"
BASE COUNT         5938 a         2688 c         3381 g         4697 t
ORIGIN      
        1 tgcggctagc tttctagttt gctctttgat ttttattgag tattagaaag gagacctcat
       61 gacacttcca gttagaaaat ccctgcacga tgcagtttta caggcttcga aagcggatac
      121 ttgggaacaa gctaccaagg aatggaatga agtttccttg atttttaacg gtatcggccg
      181 tagcaattgt gtctgtggaa atgccatcaa atacgcttat gaactcttta acggtgtcac
      241 aggccaacgc ctctttccaa ttggtagcga ctgtgttcgt cattttcatc gattgtccct
      301 tgaccagcaa ttggaagagg aagaaaaact gctcagaaag gttgaaaatc taaccagaaa
      361 agctcagaaa aaggaaaaaa tcaaggtcaa taaaagtgac tttgacgagc gacttctaaa
      421 atggctctgg gaaaaaggtg ttttcaaacc caatcgtggc aatcaatttg cgcctgagag
      481 agactaccag cttttcctag aagtctttca gggaggaagt tggaccaagg cggaaccaaa
      541 gaaaaaggct cggatggaag aagtccttga aaagtgtatc aaaccctttt tacttgggaa
      601 atcggatgac caactctacc ttgtcaagct aggcaaggag aaaattgact acgaacaaga
      661 actccgtatc caggcagaga aagaacgcaa gaagagggat aaaatcgcca agcaatatgc
      721 agacaatctg gttctagcca tgggacccgc agagcgtgct tatcaagatt actttggctt
      781 tacagagacc ctgactcaag aagaacgcaa gtgggaaaaa attctttttg gtaaaaatag
      841 agcagaacgg gctatcaagg ccaaacaata ccaaaaagag ctggaaaaag accaacgaat
      901 tgccagtcag gatccaattg aaagaaaaca gaagcagact tggctcctca attcctattt
      961 tcgtgagctt cctgaagaaa aagctcgatt ttctaggctc ttattagaat atcgaaaaag
     1021 tggtgaagta cccttttcaa ctgaatacct gtccgatcat ctcatcgact ttttctataa
     1081 aatgaaagcc tttgaatttg aaatcgcacc agaacaagtc cgagattttc taaaaaaaag
     1141 cctgcaggaa gaccatcgct catcagcaca aggaagctgg atagaaggaa ttctcctcaa
     1201 ctgcctcaaa ccatttttag aacgattagt gatatgagta acacctaccg tgtaaatttc
     1261 atggtaggtg ttattgtacc cccaaataat ataaaacaaa gtatgaaagc gcatctcaat
     1321 tttaagactt ttttgtaaat taagagtata attaaggtat actgcctttt ctatagataa
     1381 tagataatac actaatataa taaaggtctt tgtaacatat ataaatttta tttcaaggag
     1441 gaataatgga aaagtatttt ggtgaaaaac aagagcgttt ttcatttaga aaattatcag
     1501 taggacttgt atctgcaacg atttcaagtt tattttttat gtctgtatta gctagttcat
     1561 ctgtggatgc tcaagaaact gcgggagttc actataaata tgtggcagat tcagagctat
     1621 catcagaaga aaagaagcag cttgtctatg atattccgac atacgtggag aatgatgatg
     1681 aaacttatta tcttgtttat aagttaaatt ctcaaaatca actggcggaa ttaccaaata
     1741 ctggaagcaa gaatgagagg caagccctag ttgctggtgc tagcttagct gctctgggaa
     1801 ttttaatttt tgctgtttcc aagaaaaagg ttaagaataa aacggtatta catttagtat
     1861 tggttgcggg aatgggaaat ggtgtcttag tttcagtcca tgctttagaa aatcatcttt
     1921 tgctaaatta caatacggac tatgaattga cctctggaga aaaattacct attcctaaag
     1981 agatttcagg ttacacttat attggatata tcaaagaggg aaaaacgact tctgattttg
     2041 aagtaagtaa tcaagaaaaa tcagcagcca ctcctacaaa acaacaaaag gtggattata
     2101 atgttacacc aaattttgta gaccatccat caacagtaca agctattcag gaacaaacac
     2161 ctgtttcttc aactaagccg acagaagttc aagtagttga aaaacctttc tctactgaat
     2221 taatcaatcc aagaaaagaa gagaaacaat cttcagattc tcaagaacaa ttagccgaac
     2281 ataagaatct agaaacgaag aaagaggaga agatttctcc aaaggaaaag actggggtaa
     2341 atacattaaa tccacaggat gaagtgctat caggtcagtt gaacaaaccg gaactcttat
     2401 atcgtgacga aactatagaa acaaaaatag attttcaaga agaaattcaa gaaaatcctg
     2461 atttagcaga aggaactgta agagtaaaac aagaaggtgc attaggtaag aaagttgaaa
     2521 tcgtcagaat attttctgta aacaatgaag aagtttcacg agaaattatt tcaacttcaa
     2581 cgactgcgcc tgtttcaaga atagtcgaaa aaggtactaa aaaagctcaa gttataaagg
     2641 aacaagctga gactggtgca gaacataagg aagtacagtc tggagctatt gttgaacccg
     2701 caattcagcc tgaactacca gcagctgtat taaccgacaa aggtgagtca gcagtccaac
     2761 cagagttgcc agaagctgta gtaagtgata aaggcgtacc agaagttcaa ccagcgttac
     2821 cagaggcagt catgactgac aagggtgatc cagagcaggt agaaccgcta ccagaatata
     2881 caggagtaca agctggcgct attgttgaac ctgaaaaagt tgaaccggaa tatgctggag
     2941 tacaagctgg cgctattgtt gaaccagagc aggtagcacc actaccagaa tacacagggg
     3001 tgcaagccgg agcgatagtc gagccagaga aagtagaagc accgaaggaa tacacaggag
     3061 tgcaggctgg agcgatagtc gaaccagaga aggtagaagc accgaaggaa tacacaggag
     3121 tgcaagccgg agcaatagta gaaccagaaa aagtagaacc atcaaaagaa tacacagggg
     3181 tgcaggctgg cgctattgtt gaaccagagc agatagcacc actaccagaa tacacagggg
     3241 tgcaagccgg agcgatagtc gagccagaga aagtagaagc actgaaagaa tatactggta
     3301 aaatcgaaca acctagtgca gaagatacta aaccaaataa tgaaaatact aatacaccag
     3361 aagaaatgag tattcagaaa aaatctagtg cattaattaa tatgaacttt attacagatt
     3421 cgtcgaaggt tactggagta ggatcagcta cttttattgc accaaatgta cttttaacag
     3481 tagcacataa tttcattaat aattctactg ataatactac tggcgaattt agaggtgata
     3541 aatctaaaaa cgtatatgag tgggtgactc ctgatggaca aaaaggaaca tttactgcta
     3601 acaatattca tttttataat aaaaaagatt atccaaaagg atttatctat gatttagcag
     3661 tgattaagct acctgaaaca actggcagag aacatgtaga attagttaaa aattattcga
     3721 aagtaaatct taatgacaaa ctaaatgttc atggatatcc agctgggaaa tatacgcact
     3781 taaaagatgc tacggtagaa atggaacaag aatatgcgaa taacacctac ggtgttcaat
     3841 atcaaggtgg aaatcctggt atgagtggtg gaggaatatt taatgctaat ggtgaagtta
     3901 ttggtgtgca tcaaaatgga gcacaaaatc gctcaggcgg attgatttta tctcctacac
     3961 aattagcttg gattaagagt attatagcag gtaatgaaat tccaccagta tacgatgaac
     4021 tttatcgtca taaagatgag aaaaaagatg acgctaaaga tgaaaaagaa gttattaaga
     4081 aattagaact tagaaatata tcttctgtag aactatattc aaaagatggt aataagtatc
     4141 gacatgtaac ttcacttgct tctttaccaa gtaatgcaga aaattacttt atgaaagtta
     4201 aatcagagaa ctttaaagat gtgatgctac cagttacaag cattactaat gatactaaag
     4261 ataatagaga tgtttataag atagtagcaa gtgcaaatag tctgatacaa catgaaaata
     4321 ataatgtact agaaaattat acatactatt taccaaaaac tcagcaaagt gaaactgggg
     4381 tatatacatc atttaaaaat ttagtagatg caatgaatag caatcctaat ggcacattcc
     4441 gtttaggagc aactatggat gctcgtgaag ttgaacttcc agatggtcaa gaaagttatg
     4501 tgaataatgt attccatgga atattagtag gaacaaataa tgagaaatat tatgctattt
     4561 ataatttgaa aaaaccatta tttggggaat taaatggtgc tacagtagaa aaactttcac
     4621 taaaagatgt taatatttcc gcaaaggacg atactgcaac acttgcgaaa gaagcaaata
     4681 acaatactca tattgataac gttcatgctg atggagcgat agctggggaa cgtagcatag
     4741 gaggattagt atcacaagtt aataattcta ctatttctaa cagtagctat acaggtagaa
     4801 taactaatac atataaaaca gttgctagtt atcaaatcgg aggtttagta ggcaaacttt
     4861 ctggtccgag gggattaata gataagtcgt tcgcatcaat cgatttatct tcaaatgcaa
     4921 cacaaggaga ccagtctatt ggtggaatag ttggtgcagt agaaaatagt gcgcttatta
     4981 gtaatagtta tgctgaagga aatctaaata atgttcaacg ttttgcaaac gttggtggag
     5041 tagttggtaa tctttgggat ccggttggag gattagaaaa atccggtcga ctttctaatg
     5101 tactaagcga tgttaatgta acgaatggta atgctattgc aggttataat tttaatggta
     5161 taaaagcaaa tggcacatac agtaataaaa ataataaggt tgtgaacgta gtacaagaag
     5221 atgatgaaat cttaactaag gattctactg ttcaaagagg agaagtatta gaagatgcac
     5281 aaataaaaga gaaaaaagct acttttgtat ctaaaaatac tattaaaaca gaagatttta
     5341 atttctcttc tagatatgta actgactata aaaatcttga gaatgctgat tcatcaaaag
     5401 aaaaagtata taaaaatatt gaaaaactat taccgtttta taatagagaa acaattgtta
     5461 agtacggaaa tttagtagag acaagtagta atctttataa taaagaatta ttgtcagtag
     5521 tccctatgaa agataaagaa gtaattagtg atattaacaa aaataaatca agtataaata
     5581 aactattact atattacgcg gataatacat cagagacact taatgtaaat tatcaaactg
     5641 atttttcaaa tgtagcagag tatagaatag gcggtacaaa cttaatttat acaccgaata
     5701 cattacttcg caattatcaa aatattttag atgaagtatt accagcatta aatagtgtag
     5761 aatataaatc agaggcaatt agaaaagtat tagatgtttc taaggatgtt agtttaacgg
     5821 agttatattt agaagaacaa ttcaatacca caaaaactaa tttgaaagat agtttgacaa
     5881 aacttcttac tgcagatgct gcaatagctg aaaataacaa taaggtaata gataattatg
     5941 taatcgagaa aattaaaaat aataaagaag ctttacttct aggattaaca tacttagagc
     6001 gttggtacga cttcaaatat cgtgatacaa aagcgaaaga tttagtcatg taccacttgg
     6061 atttcttcgg taaatcaaat agttcagcgt tagataatgt tatcgaacta ggtaaatcgg
     6121 gatataataa cttactagca aaaaataatg ttataactta taatgtttta ttagcgaaaa
     6181 attataagac taataattta tttgatgcat tagagaaata tagaaaagca tttgtaccag
     6241 ataaaacaaa taatgagtgg tttaaagaac aaactaaagc atatattgta gaagaaaaat
     6301 ctactattaa agaggtaagt gataagcaat caatagctgg tagtccatat tcaattggag
     6361 tatatgatag attaactagc ccatcttgga aatatccaag tatggtgttg ccgctattaa
     6421 cattacctga aaaatcggtg tttattatag ccaacatttc gactataggt ttcggtgctt
     6481 atgatagata tagaagtaaa gaacatccag caggaactga tttaaatgac tatgttgaga
     6541 aaaaagctaa agaagcggct gttagattta gagatcacta tgattattgg tatagaatac
     6601 tagatgataa aaataaagaa aaattatata gaagtgttct agtctatgat gcatttagat
     6661 ttggtacaga tgaaaaagaa gataaagata catatcaagc aacttttgaa actaatcatc
     6721 cagctataaa acatttcttc ggtccagcgg gaaataatgt tgttcataat tctaatggag
     6781 catatgctac aggggatgca ttctattata tggcatatcg catgcttgat aaagatggtg
     6841 cggtaactta tacacacgaa atgacacata actcagatag agaaatttat cttggaggct
     6901 atggaagacg aaatggactt ggaccagagt tttatgctaa aggactgcta caagctcctg
     6961 atcatcctaa taatccaaca gtcactatta attccatatt aaaatatgat caatcagaag
     7021 aatcaacaag gcttcaagta gcagatccaa ctcaacgatt tggaagtgtt gatgatctaa
     7081 ataagtatat gcataatatg tttgatgtaa tatacatgct tgaaatacta gaaggtaaag
     7141 ctgtagctaa attagataca aatcaaaaat atgatttatt aagaaaaata gaaaatgaat
     7201 ataaacctga tcctgatgga aattctgttt atgcaacgaa tgttgtacgt agattaaaac
     7261 cagaagaact tactaaatta actacattta acagtttgat agaacatgat attataacaa
     7321 gaagaggtta tgtagatgaa gcaacttata agcggaatgg ctactataca attaatctat
     7381 tctcaccaat ttattcagca ttgagcagta aaataggaac accaggagat ttaatgggac
     7441 gacgtattgc atttgagtta ttggcagcca aggggtacaa agacggtatg gttccatata
     7501 tttctaatca gtatgaaaaa gaagcgaaag ctcaaggaaa agttattaca tcatatggta
     7561 aacaaatagg tttagttact gatgaaattg ttctttcaaa agtatttaat aaccagtata
     7621 attcttggat agatttcaag aaagatatgt ataaagaaag agaagataaa tttggaaagt
     7681 taaataaagt tagttttatc gatccaaacg gttcttgggc tcgacaacag aaagtgacta
     7741 ttgataatat taatagactt gaaaaaatga ttgaagatgc agtaaaattt gatgctgagg
     7801 atgaagttgc caaattatat cctgagacaa atagtagagt tcttaaactg aaaaaagcaa
     7861 tctttaaagc ttatcttgac caaaccggtg attttagaag ttcaattttt gagaataaaa
     7921 aatagtgttt actattagga aataaaaagt gaaggtggag gattagaatt gtcattatta
     7981 aaaaaagata aattttccat tcggaaaata aagggtattg ttggttcggt attcttgggg
     8041 agtcttttat ttgcaccgtc agttgttggt gcatcgactt atcattactt agattatagt
     8101 agtttgacac aaactgaacg tgatcaactc aaacaaggta gacctgatga atccaaagag
     8161 tcatatgctt tggattatga aaaagacgca ctaccaaaca caggaagttc tcaatctatt
     8221 atgactgcat tgggtttgtt agctatcggg agtcttattg tgattatcac aaaagataat
     8281 agaaataaaa aaatagctac atttttgatt gtaggggcga caggtttagt tacactatca
     8341 actgcttcag cacttaattt gaatgctaac atccatgagt ctggacgtga tggtgtgttg
     8401 caaatttctg gttacagata tgttggttac ttggagcttg atgataaaac tgtttcgtcg
     8461 gtttctccag catcaactgt ttcgccagtt gagcaaccca aagttgtaac agagaaaggc
     8521 gaaccggaag ttcatgagaa gcctgactat acgcaaccaa taggtgcaaa ccttgttgag
     8581 cctgaagttc atgagaaact agcatacact gaaccagtag ggacaacagg agtagatgaa
     8641 aatggaaact tgattgaacc acctgttaac gacatcccag aatatactga gccagtaggt
     8701 acaacaggag tggatgaaaa tggaaacttg attgagccac ctgttagcga cattccagag
     8761 tatactgaac caatatctac agtttcagaa gttgcatcag aaagagaaga gttgccttct
     8821 ttacataccg atattcggac agagactatt cctaaaacca ctatagaaga atctgatcct
     8881 agcaaattta taggcgatga ttctgttaga caagttggtg aggatggcga acgtcaaatt
     8941 gttactagct atgaagagtt acatggcaaa aaaatcagtg acccagttga aacagtaact
     9001 attttgaaag aaatgaagcc taaaattctt gtaaaaggta ccaaagaaaa acctaaagaa
     9061 aaaacggctc ctgttttgac cttagataga acaaatacaa atgtattaaa ccgatccgca
     9121 actctttctt atcatttagt taatacagat ggagtcacaa tcaataaaat tactgcgaca
     9181 attaaagatg gaaatgaaat tgtcaaaaca gtagatttga cttcagagca attagataag
     9241 caggtagaag atttaaaatt ctacaaggac tataagatag agaccactat gacctatgac
     9301 cgtggcaagg gagaagaaac tgcaacatta gaagagaaac cacttcgctt ggatttgaaa
     9361 aaagttgaaa ttaaaaatat cgcatctact aatttagtga aggtaaatga cgatggtact
     9421 gaaacaccta gtgattttat gactgaaaaa ccttcagatg aagatgtgaa gaaaatgtac
     9481 ttaaaaatta ctagtcgtga taataaagta acacgtttag cagttgataa aattgaagaa
     9541 gtgactgaag aaggtaagaa actttataaa atcactgccg aagctcaaga tttgattcaa
     9601 catacagacc caacgaaggt tcgtaacaag tatgttcatt atattgaaaa accagttcca
     9661 aaagttgatg acgtttatta taactttaaa gagttagtag atgccatgaa tgctgataaa
     9721 aatggtacat ttaaaatcgg agcagatttg aatgcaacga atgtaccaac acctaacaaa
     9781 caatatgttc caggtacgtt taagggacat ctatcaagtg ttgatggtaa acaatataca
     9841 attcataaca ttgcccgtcc cttatttgac cgtgttgaaa atggttctgt gaaaaatatt
     9901 aatttaggta atgtggatat caatatgcct tgggctgacg gaatagcacc tgttgccaat
     9961 atggtgaaaa atgcaactgt tgaagatgtt aaggtaactg gtaatgtagt tgctaataac
    10021 aatattgcgg gtatcgtcaa taaaatcgat agtggtggtc agttgacaaa tgtagccttc
    10081 atcggtaatc ttacaggtgt tggtgataaa ggtcaatata tggctggcat tgccggtgag
    10141 atttggagag gtaatcttgc aaaagcatat gtcgaggctg atattgttgc taacagagcc
    10201 cgtataggtg gtttagttgc taaaacagat aatggtaacg actctatggg aattggtaaa
    10261 tacggttcaa ttcgtaaatc agtcaccaaa ggaaccatta agactaaagt tttgtttgaa
    10321 acaggtggat ttatcaatag caatcttcct tttggtaaac ttgaagataa tatttcaatg
    10381 atgagagttg aaaatggtga agagttcttt ggttcttccg atttggacta cgatggtggt
    10441 tatttcacaa atggctggtt agagcgtaac tttgttgtca aaggtgtcag ttcaggtaag
    10501 cattcataca aacgttctcg tgacaaaatt aaagaaatta gtcaagatga agctaataag
    10561 agaattgcaa attttggact tactgctgat aaatacgaaa tcaacgaacc tgtggtcaat
    10621 cgcttaaatc gtttaaccag aagagaagat gaatataagt caactcaaga ctacaaatcc
    10681 gaacgtgatt tagcttatcg taatattgag aaacttcaac cattttataa taaagaatgg
    10741 attgtcaacc aaggtaacaa acttgcagaa gattcaaact tagctaagaa agaagtcctt
    10801 tctgttacgg ggatgaagga tggtcaattc gtgaccgatt tatcagatat tgataagatt
    10861 atggttcact atgctgatgg tactaaggaa gaaatggatg ttactaagaa tactgattct
    10921 aaagtccaac aagtgcgtga atatagtgta tctggtcttg gtgatgttgt ttatacaccg
    10981 aatatggttg ttaaaaatcg tgataaattg attgctgatg ttaaatctca attatcaagt
    11041 gtggaattga tttcacaaga agtaagagat ttaatgagta gacgtgataa acctgcagag
    11101 aatacggatg aacgtaagaa tggttatatt aaagatctat acttagaaga aagctttgcc
    11161 gaagtgaagc aaaatctaga taagttagtc aaatccttgg tcgaaaatga agaccatcaa
    11221 ttgaatggtg atgaagctgc gataaaatca cttctcaaga aagtggaaac caataaagct
    11281 aaaatcatga tggctctgac ttatctcaat cgttactatg atatcaaata cggtgacata
    11341 agtataaaaa acatcatgat gttcaaacct gatttttatg gtaaaacacc aagtgttatt
    11401 gacagactca tcaacatcgg ttcaagtgaa aagaacttga aaggggatcg gactcaggat
    11461 gcttaccgtg aaatcatcgc aggtaatact ggtaaaagta atttgcgtaa cttcttagaa
    11521 tacaacatgc gtctgtttac agaggataaa gacatcaatg attggtttat ccactcagct
    11581 aagaatgttt atgtttcaga acctaagaca acaaatacag agttgaaaga taaacgtcat
    11641 cgtgtgttcg atggtttaga taacggtgtt catggtcgta tgattttacc acttctaacg
    11701 cttaaagatg cccatatgtt cttaatttca acatataaca cgatggcgta cagttcattt
    11761 gagaaatatg gaaaacatac agaagaagct cgtaatgagt tcaaaactaa gattgatgaa
    11821 gttgcacatg ctcaacaaac ttatttagat ttctggtcca gattagctct gcctaatgtt
    11881 cgtgatagac ttcttaagag tcaaaatatg gtaccgacac cagtttggga taaccagacc
    11941 tacaatggtt ctcctgtagg tcgtcgagga tttgacagta aaggtaaccc tatagctcca
    12001 attcgtgaat tatatggtcc aacatggcga caccatgata gagactggcg tatgggcgct
    12061 atggcatcaa tattccctaa tccaaataat gatgacaagg tcttgtttat ggtgacggat
    12121 atgattagcc catttggtat ttcagccttt actcacgaaa caacacacgt aaacgataga
    12181 atgctttact tcggtggtca taagcatcgt caaggtacag acgttgaagc ctatgctcaa
    12241 ggtatgttgc aaacacctga cagctcaacg actaatggtg aatacggcgc acttggaatt
    12301 aacatggctt accatcgtcc aaatgatggt aaccaatggt acaacccaga tcctgacaaa
    12361 ttaaagacac gtgatgacat tgaccgctac atgagaaact acaatgaagc tatgatgttg
    12421 cttgatcatg tagaagctga tgctgtactt cctaaaatta aaggagacaa tagtaagtgg
    12481 ttcaagaaga ttgacaaaga aatgcgctct aagattcagt ataatgatct tttaggtcca
    12541 aaccaatggg atagtatccg tgatttgaaa gatgaagaaa aggtaatgac tttatctagc
    12601 gtcaatgatt tagtggataa taacttcatg acaaaacatg gaaatccagg taatggacgt
    12661 tatagaccag aagattttac accaaactca gcttacgtaa atgtcaatat gatggcagga
    12721 atttacggtg ggaatacgag tcaaggtgct cctggttcat tatcatttaa gcacaatgct
    12781 ttccgtatgt ggggctatta tggttatgaa aatggcttta ttagttatgt atcaaataaa
    12841 tacaaagcag aagcagataa aaacaaccac ggtttactaa gcgataagct aataattaat
    12901 aaagtatcga aaggaaactt taatactctt gaagagtgga agagacattg gtacggggaa
    12961 gttcttgcta aagctaagaa aggttttgag gctatcgata ttgatggcgt ccatatcagt
    13021 aactatgatg agttaaggcc tttatttgat aaagcagttg aagaagattt gaagaaacca
    13081 gatgacttct ctcacactgt tgctcttaaa tctaaggtct tcaaagccct tcttaaaaac
    13141 acagacggtt tctttaataa actgtttaaa gaagacattt aaatgtttag aatatagaag
    13201 gaacagtttt ttgctccctc tgaaaagtca tcatttgatg gcttttttct atatagggta
    13261 cttgaaaggc tatcatcgga caaaataaag aaggcatgat ataatataag gtagatttct
    13321 atgtcataaa acaaaaaact gtttgaacat cattcatttg agaacccttt atgttcaaac
    13381 gatagtaaaa taaaatagga tctctaaacc cttgctacga aaggaaaaaa actcaatggc
    13441 tactattcaa tggtttcctg gtcacatgtc taaagcgcgt cgacaggtgc aggaaaattt
    13501 aaaatttgtt gattttgtaa cgattttggt ggatgcacgc ttacctctat ctagtcaaaa
    13561 tcctatgttg accaagattg ttggtgataa accaaaactc ttgattttaa ataaggcgga
    13621 tttggctgat ccagcaatga ccaaggaatg gcgtcagtat tttgaatcac aaggaatcca
    13681 aactctggct atcaactcca aggagcaagt gactgtaaaa gttgtaacag atgcggccaa
    13741 gaagctcatg gctgataaga ttgctcgcca gaaagaacgt gggattcaga ttgaaacctt
    13801 gcgtactatg attatcggga ttccaaacgc tggtaaatca actctgatga accgtttggc
    13861 tggtaaaaag attgctgttg ttggaaacaa gccaggggtc acaaaaggtc aacaatggct
    13921 taaaaccaat aaagacctgg aaatcttgga tacaccgggg attctctggc ctaagtttga
    13981 ggatgaaact gttgcactta agttggcatt gactggagct atcaaggatc agttgcttcc
    14041 tatggatgag gttaccattt ttggtatcaa ttatttcaaa gaacattatc cagaaaagct
    14101 ggctgaacgc ttcaaacaaa tgaaaattga agaagaagcg cctgtgatta ttatggatat
    14161 gacccgcgcc ctcggtttcc gtgatgacta tgaccgtttt tacagtctct tcgtgaagga
    14221 agtccgtgat ggcaaactcg gtaactatac cttagataca ttggaagacc tcgatggcaa
    14281 cgattaaaga aatcaaagaa ttccttgtga cagtcaagga gttagaaagc cctatttttt
    14341 tagagcttga aaaggataat cgctcaggag ttcaaaagga aatcagcaag cgtaaaagag
    14401 ccattcaagc tgaattagat gaaaatttgc gcttggaatc catgctttct tatgaaaaag
    14461 aactttataa gcaaggattg accttaattg taggtattga tgaggttggt cgtggtcctc
    14521 ttgctggtcc tgtagtcgct gcggccgtca ttttacctaa aaattgtaag attaaaggtc
    14581 tcaacgacag caagaaaatt cctaaaaaga aacatctgga gattttccaa gccgttcaag
    14641 accaagcctt gtcgattgga attggtatca tagataatca ggtcatcgac caagtcaaca
    14701 tctatgaagc aaccaaacta gccatgcaag aagcaatctc ccagctcagc cctcaaccag
    14761 agcacctttt gattgatgcc atgaaactgg acttgcccat ttcacaaacc tccattatca
    14821 aaggagatgc caactccctc tctatcgcag cagcatctat agtagccaag gtaacacgtg
    14881 atgaattgat gaaggaatac gatcagcagt tccctggcta tgatttcgct actaatgcag
    14941 gatatggcac agctaaacat ctggaaggcc tcacaaaact aggagttacc ccaattcacc
    15001 gaaccagctt tgaacccgtt aaatcactgg ttttaggtaa aaaagaaagt taattgaaag
    15061 gaaataccat ggaggaacag tcggaaatag tccgttctaa gaaagaattc gcctttgcat
    15121 ccagcactat actatcccaa gttggtcgag gaatcattgt cggcctcatc gttggaatta
    15181 tcgtcggatc ctttcgtttc ttaattgaaa agggcttcca cctgatacaa ggagtttatc
    15241 aagatcaagg gtacttagtg cgcaatcttt ttgtactggt tttgttttat atactcatct
    15301 gttggctcag tgccaaacta acacggtcag aaaaagatat taaaggctca ggaattcctc
    15361 aagtcgaagc cgaactgaaa ggcctcatgt ccctcaactg gtggggcatt ctttggaaaa
    15421 aatatgtgct aggtattctt gctattgcca gtggactcat gctgggtcga gagggaccca
    15481 gtattcaact tggagcagtt ggtggtaaag gaattgccaa gtggctcaaa tccagtccag
    15541 tagaggaacg ttccttgatt gccagtggag ctgcagcagg tttagccgca gcctttaatg
    15601 ctcctattgc agcacttctc tttgttgtag aagaagtcta tcaccatttt tcgcgctttt
    15661 tctgggtctc aactctagca gccagcatcg tagcaaactt tgtgtctcta ctcatgttcg
    15721 gtttgacacc agtattggat atgccagata acattcctcc catgacccta gatcagtatt
    15781 ggatatatct cgtcatggga attttccttg gattttcagg ttttctctat gagaaagctg
    15841 tattaaacgt tggaagagtt tatgacttga ttggtcaaaa aatccatttg gatagggctt
    15901 attatcccat cttggctttt atccttatca taccagtcgg aatcttctta cctcaaatca
    15961 ttggtggcgg aaatcagctt gtcctttctt taactgaaca aaattttagt ttccaagttt
    16021 tattagctta ctttttaatc cgctttattt ggagtatgat tagctatgga agtggactgc
    16081 caggaggaat tttcctcccc attttagctc ttggttcttt gcttggtgcc ttagttggtg
    16141 ttatctgtgt caatcttgga cttgtcagtc aagagcaatt ccctatattt gtcattatag
    16201 gaatgagtgg ctattttgga gccatatcaa aagctccctt aaccgctatg atcctcgtaa
    16261 ctgagatggt aggagatatt cgcaacctta tgccacttgg tcttgtcact cttgtttctt
    16321 atattatcat ggatttgctc aaaggtacgc cagtctatga agccatgctg gaaaaaatgc
    16381 ttccagaaga agtatctagc gaaggagaag ttacacttat cgaaatacca gtttctgata
    16441 aaattgctgg gaaacaagtt catgaactca acttaccaca caacgtcctc atcacaactc
    16501 aagtccataa tggcaagagc caaacggtta acggctcaac cagaatgtat ctgggtgata
    16561 tgattcacct ggttattcca aaaagtgaaa ttggaaaagt caaagatttg ttgttgtagt
    16621 atgatcattt acataattta tgttatgtaa atgatcggtt tgatttattt agaaaaccga
    16681 ttctcagaaa tgagatcggt tatt
//
LOCUS       DAVHTH010000045        16176 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.045, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000045 DAVHTH010000000
VERSION     DAVHTH010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16176)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16176)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16176
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.045"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            145..6846
                     /locus_tag="VVR63_001538"
     CDS             145..6846
                     /locus_tag="VVR63_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HEU6129544.1"
                     /translation="MGKGHWNRKRVYSIRKFAVGACSVMIGTCAVLLGGNIAGESVVY
                     ADETLITHTAEKPKEEKMIVEEKADKALETKNVVERTEQSEPSSTEAIASEKKEDEAV
                     TPKEEKVSAKPEEKAPRIESQASSQEKPLKEDAKAVTNEEMNQMIEDRKVDFNQNWHF
                     KLNANSKEAIKPDADVSTWKKLDLPYDWSIFNNFDHESPAQNEGGQLNGGEAWYRKTF
                     KLDEKDLKKNVRLTFDGVYMDSQVYVNGQLVGHYPNGYNQFSYDITKYLHKDGRENVI
                     AVHAVNKQPSSRWYSGSGIYRDVTLQVTDKVHVEKNGTTILTPKLEEQQHGKVETHVT
                     SKIVNTDDKDHELVAEYQIVERGGHAVTGLVRTASRTLKAHESTSLDAILEVERPKLW
                     TVLNDKPALYELITRVYRDGQLVDAKKDLFGYRYYHWTPNEGFSLNGERIKFHGVSLH
                     HDHGALGAEENYKAEYRRLKQMKEMGVNSIRTTHNPASEQTLQIAAELGLLVQEEAFD
                     TWYGGKKPYDYGRFFEKDATHPEARKGEKWSDFDLRTMVERGKNNPAIFMWSIGNEIG
                     EANGDAHSLATVKRLVKVIKDVDKTRYVTMGADKFRFGNGSGGHEKIADELDAVGFNY
                     SEDNYKALRAKHPKWLIYGSETSSATRTRGSYYRPERELKHSNGPERNYEQSDYGNDR
                     VGWGKTATASWTFDRDNAGYAGQFIWTGTDYIGEPTPWHNQNQTPVKSSYFGIVDTAG
                     IPKHDFYLYQSQWVSVKKKPMVHLLPHWNWENKELASKVADSEGKIPVRAYSNASSVE
                     LFLNGKSLGLKTFNKKQTSDGRTYQEGANANELYLEWKVAYQPGTLEAIARDESGKEI
                     ARDKITTAGKPAAVRLIKEDHAIAADGKDLTYIYYEIVDSQGNVVPTANNLVRFQLHG
                     QGQLVGVDNGEQASRERYKAQADGSWIRKAFNGKGVAIVKSTEQAGKFTLTAHSDLLK
                     SSQVTVFTGKKEGQEKTVLGTEVPKVQTIIGEAPEMPTTVPFLYSDGSRAERPVTWSS
                     VDVSKPGIVTVKGMADGREVEARVEVIALKSELPVVKRIAPNTDLNSVDKSVSYVLTD
                     GSVQEYEVDSWEITEVDKAKLSVAGSRIQMTGQLAGETIHATLVVEEGNAAAPVVPTV
                     TVGGEAVTGLTSRQPMQYRTLSYGAQLPEVTASAENADVTVLQASAANGMRASIFVQP
                     KDGGPLQTYAIQLLEEAPKIAHLSLQVEKADSLKEDQTVKLSVRAHYQDGTQAVLPAD
                     KVTFSTSGEGEVAIRKGMLELHKPGAVTLKAEYEGAKGQVELTIQANTEKKIAQSIRP
                     VNVVTDLHQKPTLPTTVTVEYDKGFPKAHKVTWQAIPKEKLDSYQTFEVLGKVEGIDL
                     EARAKVSVEGIVSVEEVSVTTPIAEAPQLPESVRTYDSNGHVSSAKVAWDAIRPEQYA
                     KEGVFTVNGRLEGTQLTTKLHVRVSAQTEQGANISDQWTGSELPLAFASDSNPSDPVS
                     NVNDKLISYNNQPANRWTNWNRTNPEASVGVLFGDSGILSKRSVDNLSVGFHEDHGVG
                     APKSYVIEYYVGKTVPTAPKNPSFVGNEDHVFNDSANWKPVTNLKAPAQLKAGEMNHF
                     SFDKVETYAVRIRMVRADNKLGTSITEVQIFAKQVAAAKQGQTRIQVDGKDLANFNPD
                     LTDYYLESVDGKVTAVTASVSNNGLATVVPSVREGEPVRVIAKAENGDILGEYRLHFT
                     KDKNLLSHKPVAAVKQARLLQVGQALELPTKVPVYFTGKDGYETKNLTVEWEEVPAEN
                     LIKAGQFTVRGHVLGSNLVAEITVRVTDKLGETLSDNPNYDENSNQAFASATNDIDKN
                     SHDRVDYLNDGDHSENRRWTNWSPTPSSNPEVSAGVIFRENGKIVERTVAQGKVQFFA
                     DSGTDAPSKLVLERYVGPEFEVPTYYSNYQAYDADHPFNNPENWEAVPYRADKDIAAG
                     DEINVTFKDIKAKAMRWRMERKADKSGVAMIEMTFLAPSELPQESTQSKILVDGKELA
                     DFAENRQDYQITYKGQRPKVSVEENNQVASTVVDSGEDSLPVLVRLVSESGKQVKEYR
                     IHLTKEKPVSDKTVAAVQEDLPKLEFVEKDLAYKTVEKKDSTLYLGETRVEQEGKVGK
                     ERIFTAINPDGSKEEKLREVVEVPTDRIVLVGTKPVAQEAKKPQVSEKADTKPIDSSE
                     ASQTNKAQLPNTGSAAGQAAVAAGLALLGLSAGLVVTKGKKED"
     gene            complement(7094..7943)
                     /locus_tag="VVR63_001539"
                     /pseudo
     CDS             complement(7094..7943)
                     /locus_tag="VVR63_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007722232.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(8154..8513)
                     /locus_tag="VVR63_001540"
     CDS             complement(8154..8513)
                     /locus_tag="VVR63_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HEU6129545.1"
                     /translation="MGMILMKLASILLLILTLVVCIILTKLFRLKKLGRNFADLAFPV
                     LVFEYYLITTKTFTHNFLPRLGLALSILAIILVFFFLLKKRSFYYPKFIKFFWRAGFL
                     LTLIMYIEMIVELFLMK"
     gene            8605..9561
                     /locus_tag="VVR63_001541"
                     /pseudo
     CDS             8605..9561
                     /locus_tag="VVR63_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002881980.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein.; internal stop;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
     gene            9545..10102
                     /locus_tag="VVR63_001542"
     CDS             9545..10102
                     /locus_tag="VVR63_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEU6129546.1"
                     /translation="MKRPLEMAHDFLAEVVTKEDVVVDATMGNGHDTLFLAKLAKQVY
                     AFDIQKQALEKTQERLHQAGLTNAQLILQGHETLDQFVTKAKAGIFNLGYLPSADKSV
                     ITRPQTTIEALEKLCGLLVKGGRIAIMIYYGHEGGDLERDAVLDFVIQLNQQEYTAAI
                     YRTLNQVNNPPFLVMIEKLERYRHG"
     gene            10095..10349
                     /locus_tag="VVR63_001543"
     CDS             10095..10349
                     /locus_tag="VVR63_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6129547.1"
                     /translation="MDKQYLHEKLDAMRQNFVESTYHERAVGVLDQAHMSKKMLKIKK
                     KLVALEMERCQRKIEHKDCSKIDQKIKEQKEIFESCCKKD"
     gene            10361..12415
                     /locus_tag="VVR63_001544"
     CDS             10361..12415
                     /locus_tag="VVR63_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HEU6129548.1"
                     /translation="MELLIYLILFLLVLIVSSTTNKLLPFLPLPLVQILLGIVIGLFL
                     PNTDFHLNTELFLALVIGPLLFREAEEADVTAILKHWRIIVYLIFPVIFISTLSLGGL
                     AHLLWFSLPLAACLAVGAALGPTDLVAFASLSERFSFPKRVSNILKGEGLLNDASGLV
                     AFQVALTAWTTGAFSLGQASSSLIFSILGGFLIGFLTAMTNRFLHTFLLSVRATDIAS
                     ELLLELSLPLVTFFLAEEVHVSGIIAVVVAGILKASRFKKITLLEAQVDTVTETVWHT
                     VTFMLNGSVFVILGMELEMIAEPILTNPIYNPLLLLLSLIALTFVLFVIRFIMIYGYY
                     AYRTRRLKKKLNKYMKDMFLLTFSGVKGTVSIATILLIPSNLEQEYPLLLFLVAGVTL
                     VSFLTGLLVLPHLSDEEEESKDYLMHIAILNEVTLELEKELEDTRNKLSLYAAIDNYH
                     GRIENLILSQENQDDQEDWAALKLLILSIESDGLEQAYEEGNISNRAYRVYQRYLKNI
                     EQGINRKLASRLTYYFLVSLRILRFLLHEVFTLGKTFRSWKNKEQSRLRALDYDQIAE
                     LYLANTEMIIESLENLKGVYRRSLISFMQESRLRETAIISSGAFVERVINRVKPNNID
                     EMLRGYYLERKLIFEYEEKRLITTKYAKKLRQNVNNLENYSLKEAANTLPYDMVELVR
                     RN"
     gene            12594..13454
                     /locus_tag="VVR63_001545"
     CDS             12594..13454
                     /locus_tag="VVR63_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HEU6129549.1"
                     /translation="MKKWWKELIDKPLLKAFLHYYQASDSELTSVAVAYYWLISIFPL
                     LLVVVNILPYFQIPVGEFLCFMKDVLPPSLYEGVEKIAREVLTQPSTGLLSFSVLSAL
                     WSFSKSMNFLQKAFNKAYGVEKSRGLISHQMLSLLVSFGLQLLFAFALFLILFGQMIL
                     ALLAHYWTKDGIIYQALQGLAGPLIYALLFAILVMLYYFLPNISNRKISYTLPGSAFV
                     LLVILGLLTLFSSYLNYYVHHLVDVRILGSVLLVVMMFWFILIAKIVILGAVINASMQ
                     SLRDPVFKKD"
     gene            13665..14375
                     /gene="ccdA2"
                     /locus_tag="VVR63_001546"
     CDS             13665..14375
                     /gene="ccdA2"
                     /locus_tag="VVR63_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEU6129550.1"
                     /translation="MGHIFFFLSVFLAGILSFFSPCILPLLPVYTGVLLDDKDGAQAS
                     SGKFSISVTSLLRTLAFIAGISFIFILLGYGAGFLGDLLYASWFQYLTGAIIILLGLH
                     QMEILHFKGLYKEKRLQLQGQGQNGKGYSQAFLLGLTFSFAWTPCVGPVLGSVLALAA
                     SGGSGAWQGAGLMLVYTLGLALPFLLLALTSSYVLKHFRKLHPYLGILKKVGGFLIIV
                     MGLLVLFGNASILSQLFE"
     gene            14395..14961
                     /locus_tag="VVR63_001547"
     CDS             14395..14961
                     /locus_tag="VVR63_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HEU6129551.1"
                     /translation="MKKWQTCVLGAGSLLCLTACSGKSVTSEHQTKDEMKTEQTASKT
                     SAAKGKEVADFELMGVDGKTYRLSDYKGKKVYLKFWASWCSICLASLPDTDEIAKEAG
                     DDYVVLTVVSPGHKGEQSEADFKNWYKGLDYKNLPVLVDPSGKLLETYGVRSYPTQAF
                     IDKEGKLVKTHPGFMEKDAILQTLKELA"
     gene            14972..16084
                     /gene="msrB"
                     /locus_tag="VVR63_001548"
     CDS             14972..16084
                     /gene="msrB"
                     /locus_tag="VVR63_001548"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEU6129552.1"
                     /translation="MNDKLKIFLLLGVFFLAITGFYVLLIRNAGQTDASQIEKAAVSQ
                     GGKAVKKTEISEDADLHEIYLAGGCFWGVEEYFSRVPGVTDAVSGYANGRGETTKYEL
                     INQTGHAETVHVTYDAKQISLKEILLHYFRIINPTSKNKQGNDVGTQYRTGVYYTDDK
                     DLEVINQVFDEVAKKYDQPLAVEKENLKNFVVAEDYHQDYLKKNPNGYCHINVNQAAY
                     PVIDASKYPKPSDEELKKTLSPEEYAVTQENQTERAFSNRYWDKFESGIYVDIATGEP
                     LFSSKDKFESGCGWPSFTQPISPDVVTYKEDKSYNMTRMEVRSRVGDSHLGHVFTDGP
                     QDKGGLRYCINSLSIRFIPKDQMEEKGYAYLLDYVD"
BASE COUNT         4912 a         3059 c         3575 g         4630 t
ORIGIN      
        1 catatctacg gcaaggcgac gctgacgaag tttgaattgg attttcgcag agtgtaaatt
       61 gttgaaacta ggttgtcata ccatgtatac cacttgggct ttggtagtag ctaactgcac
      121 taaatataat ataaggaggg ttttatgggg aaaggccatt ggaatcggaa aagagtttat
      181 agcattcgta agtttgctgt gggagcttgc tcagtaatga ttgggacttg tgcagttcta
      241 ttaggaggaa atatagctgg agaatctgta gtttatgcgg atgaaacact tattactcat
      301 actgctgaga aacctaaaga ggaaaaaatg atagtagaag aaaaggctga taaagctttg
      361 gaaactaaaa atgtagttga aaggacagaa caaagtgaac ctagttcaac tgaggctatt
      421 gcatctgaga agaaagaaga tgaagccgta actccaaaag aggaaaaagt gtctgctaaa
      481 ccggaagaaa aagctccaag gatagaatca caagcttcaa gtcaagaaaa accgctcaag
      541 gaagatgcta aagctgtaac aaatgaagaa atgaatcaaa tgattgaaga caggaaagtg
      601 gattttaatc aaaattggca ctttaaactc aatgcaaatt ctaaggaagc cattaaacct
      661 gatgcagacg tatctacgtg gaaaaaatta gatttaccgt atgactggag tatctttaac
      721 aatttcgatc atgaatctcc tgcacaaaat gaaggtggac aactcaacgg tggggaagct
      781 tggtatcgca agactttcaa actagatgaa aaagacctca agaaaaatgt tcgccttact
      841 tttgatggcg tctacatgga ttctcaagtt tatgtcaatg gtcagttagt ggggcattat
      901 ccaaatggtt ataaccagtt ctcatatgat atcaccaaat accttcacaa agatggtcgt
      961 gagaatgtga ttgctgtcca tgcagtcaac aaacagccaa gtagccgttg gtattcagga
     1021 agtggtatct atcgtgatgt gactttacaa gtgacagata aggtgcatgt tgagaaaaat
     1081 gggacaacta ttttaacacc aaaacttgaa gaacaacaac atggcaaggt tgaaactcat
     1141 gtgaccagca aaatcgtcaa tacggacgac aaagaccatg aacttgtagc cgaatatcaa
     1201 atcgttgaac gaggtggtca tgctgtaaca ggcttagttc gtacagcgag tcgtacctta
     1261 aaagcacatg aatcaacaag cctagatgcg attttagaag ttgaaagacc aaaactctgg
     1321 accgttttaa atgacaaacc tgccttgtac gaattgatta cgcgtgttta ccgtgacggt
     1381 caattggttg atgctaagaa ggatttgttt ggttaccgtt actatcactg gactccaaat
     1441 gaaggtttct ctttgaatgg tgaacgtatt aaattccatg gagtatcctt gcaccacgac
     1501 catggggcgc ttggagcaga agaaaactat aaagcagaat atcgccgtct caaacaaatg
     1561 aaggagatgg gagttaactc tatccgtaca acccacaacc ctgctagtga gcaaaccttg
     1621 caaatcgcag cagaactagg tttactcgtt caggaagagg cctttgatac gtggtatggt
     1681 ggcaagaaac cttatgacta tggacgtttc tttgaaaaag atgccactca cccagaagct
     1741 cgaaaaggtg aaaaatggtc tgattttgac ctacgtacca tggtcgaaag aggcaaaaac
     1801 aaccctgcta tcttcatgtg gtcaattggt aatgaaatag gtgaagctaa tggtgatgcc
     1861 cactctttag caactgttaa acgtttggtc aaggttatca aggatgttga taagactcgc
     1921 tatgttacca tgggagcaga taaattccgt ttcggcaatg gtagcggagg gcatgagaaa
     1981 attgctgatg aactcgatgc tgttggattt aactattctg aagataatta caaagccctt
     2041 agagctaagc atccaaaatg gttgatttac ggttcagaaa catcatcagc aacccgtaca
     2101 cgaggaagtt actatcgccc tgaacgtgaa ttgaaacata gcaatggacc tgagcgtaat
     2161 tatgaacagt cagattatgg aaatgatcgt gtgggttggg ggaaaacagc aaccgcttca
     2221 tggacttttg accgtgacaa cgctggctat gctggacagt ttatctggac aggtacggac
     2281 tatattggtg aacctacacc atggcacaac caaaatcaaa ctcctgttaa gagctcttac
     2341 tttggtatcg tagatacagc cggcattcca aaacatgact tctatctcta ccaaagccaa
     2401 tgggtttctg ttaagaagaa accgatggta caccttcttc ctcactggaa ctgggaaaac
     2461 aaagaattag catccaaagt agctgactca gaaggtaaga ttccagttcg tgcttattcg
     2521 aatgcttcta gtgtagaatt gttcttgaat ggaaaatctc ttggtcttaa gactttcaat
     2581 aaaaaacaaa ccagcgatgg gcggacttac caagaaggtg caaatgctaa tgaactttat
     2641 cttgaatgga aagttgccta tcaaccaggt accttggaag caattgctcg tgatgaatct
     2701 ggcaaggaaa ttgctcgaga taagattacg actgctggta agccagcggc agttcgtctt
     2761 attaaggaag accatgcgat tgcagcagat ggaaaagact tgacttacat ctactatgaa
     2821 attgttgaca gccaggggaa tgtggttcca actgctaata atctggttcg cttccaattg
     2881 catggccaag gtcaactggt cggtgtagat aacggagaac aagccagccg tgaacgctat
     2941 aaggcgcaag cagatggttc ttggattcgt aaagcattta atggtaaagg tgttgccatt
     3001 gtcaaatcaa ctgaacaagc agggaaattc acccttactg ctcactctga tctcttgaaa
     3061 tctagtcaag tcactgtctt tactggtaag aaagaaggac aagaaaagac tgttttgggg
     3121 acagaggtgc caaaagtaca gaccattatt ggagaggcac ctgaaatgcc taccactgtt
     3181 ccgtttctat acagtgatgg tagtcgtgca gaacgtcctg taacctggtc ttcagtagat
     3241 gtgagcaagc ctggtattgt aacggtgaaa ggtatggctg acggacgaga agtagaagct
     3301 cgtgtagaag tgattgctct taaatcagag ctaccagttg tgaaacgtat tgctccaaat
     3361 actgacttga attctgtaga caaatctgtt tcctatgttt tgactgatgg aagtgtacaa
     3421 gagtacgaag tagatagctg ggagattacg gaagtagata aagccaaact ttcagtagct
     3481 ggatcacgta ttcaaatgac tggtcagtta gctggagaaa ctattcatgc aacccttgtg
     3541 gtagaagaag gaaatgctgc agcacctgta gtgccaactg ttactgttgg aggtgaagca
     3601 gtaacaggtc ttactagtcg acaaccaatg caatatcgta ctctatctta tggtgcccaa
     3661 ttgccagaag tcacagcaag tgctgaaaat gctgatgtga cagttcttca agcaagcgca
     3721 gcaaacggca tgcgtgcaag catatttgtt cagcctaaag atggtggccc tcttcaaacc
     3781 tatgcaattc aattactaga agaagcacca aaaattgctc acttgagctt gcaagtggaa
     3841 aaagctgaca gtctcaaaga agaccaaact gtcaaattgt cggttcgagc tcactatcaa
     3901 gatggaacgc aagctgtatt accagctgat aaagtaacct tctctacaag tggtgaaggg
     3961 gaagtcgcaa ttcgtaaagg aatgcttgag ttgcataagc caggagcagt cactctcaaa
     4021 gcggaatatg agggagctaa aggccaagtt gaactcacta tccaagccaa tactgagaag
     4081 aagattgcgc aatctatccg tcctgtaaat gtagtcacag atttgcatca aaaacctact
     4141 cttccaacaa cagtaacggt tgagtatgac aaaggtttcc ctaaagctca caaagtcact
     4201 tggcaagcta ttccgaaaga aaaactagac tcctatcaaa catttgaagt actaggtaaa
     4261 gttgaaggaa ttgaccttga agcgcgtgca aaagtctctg tagaaggtat cgtttcagtt
     4321 gaagaagtca gtgtgacaac tccaatcgca gaagcaccac aattaccaga aagtgttcgg
     4381 acatatgatt caaatggtca cgtttcatca gctaaggttg catgggatgc gattcgtcca
     4441 gagcaatacg ctaaggaagg tgtctttaca gttaatggtc gcttagaagg tactcaatta
     4501 acaactaaac ttcatgttcg cgtatctgct caaactgagc aaggtgcaaa catttctgac
     4561 caatggaccg gttcagaatt gccacttgcc tttgcttcag actcaaatcc aagcgaccca
     4621 gtttcaaatg ttaatgacaa gctcatttcc tacaataacc aaccagccaa tcgttggaca
     4681 aactggaatc gtactaatcc agaagcttca gtcggtgtcc tattcggaga ttcaggtatt
     4741 ttgagcaaac gttcagttga taacttaagc gttggcttcc atgaagacca tggagttggt
     4801 gcaccgaagt cttatgtgat tgagtattat gttggtaaga ctgtcccaac agctcctaaa
     4861 aaccctagtt ttgttggtaa tgaggaccat gtctttaatg attctgccaa ctggaaacca
     4921 gttactaatc taaaagcccc tgctcaactc aaggctggag aaatgaacca ctttagcttt
     4981 gataaagttg aaacctatgc tgttcgtatt cgcatggtga gagcagacaa caaactagga
     5041 acgtctatca cagaggtaca aatctttgcg aaacaagttg cggcagccaa gcaaggacaa
     5101 acaagaatcc aagttgacgg taaagactta gcaaacttca accctgattt gacagactac
     5161 taccttgagt ctgtagatgg aaaagttacg gcagtcacag caagtgttag caacaatggc
     5221 ctcgctaccg tcgttccaag cgttcgtgaa ggtgagccgg ttcgtgtcat cgcgaaagct
     5281 gaaaatggcg acatcttagg agaataccgt ctgcacttca ctaaggataa gaacttactt
     5341 tctcataaac cagttgctgc ggttaaacaa gctcgcttgc tacaagtagg tcaagcactt
     5401 gaattgccga ctaaggttcc agtttacttc acaggtaaag acggctacga aacaaaaaac
     5461 ctgacagttg aatgggaaga agttccagcg gaaaatctga taaaagcagg tcaatttacc
     5521 gttcgaggcc atgtccttgg tagtaacctt gttgctgaga tcactgtacg agtgacagac
     5581 aaacttggtg agactctttc agataaccct aactatgatg aaaacagtaa ccaggccttt
     5641 gcttcagcaa ccaatgatat tgacaaaaac tctcatgacc gcgttgacta tctcaatgac
     5701 ggagatcatt cagaaaatcg tcgttggaca aactggtcac caacaccatc ttctaatcca
     5761 gaagtatcag cgggtgtgat tttccgtgaa aatggtaaga ttgtagaacg gactgttgca
     5821 caaggaaaag ttcagttctt tgcagatagt ggtacggatg caccatctaa actcgtttta
     5881 gaacgctatg tcggtccaga gtttgaagtg ccaacctact attcaaacta ccaagcctac
     5941 gacgcagacc atccattcaa caatccagaa aattgggaag ctgttcctta tcgtgcggat
     6001 aaagacattg cagctggtga tgaaatcaac gtaacattta aagatatcaa agccaaagct
     6061 atgagatggc gtatggagcg taaagcagat aagagcggtg ttgcgatgat tgagatgacc
     6121 ttccttgcac caagtgaatt gcctcaagaa agcactcaat caaagattct tgtagatgga
     6181 aaagaacttg ctgatttcgc tgaaaatcgt caagactatc aaattaccta taaaggtcaa
     6241 cggccaaaag tctcagttga agaaaacaat caagtagctt caactgtggt agatagtgga
     6301 gaagatagcc ttccagtact tgttcgcctc gtttcagaaa gtggaaaaca agtcaaggaa
     6361 taccgtatcc acttgactaa ggaaaaacca gtttctgata agacagttgc tgctgtacaa
     6421 gaagatcttc caaaactcga atttgttgaa aaagatttgg catacaagac agttgagaaa
     6481 aaagattcaa cactgtatct aggtgaaact cgtgtagaac aagaaggaaa agttggaaaa
     6541 gaacgtatct ttacagcgat taatcctgat ggaagtaagg aagaaaaact ccgtgaagtg
     6601 gtagaagttc cgacagaccg catcgtcttg gttggaacca aaccagtagc tcaagaagct
     6661 aaaaaaccac aagtgtcaga aaaagcagat acaaaaccaa ttgattcaag tgaagctagt
     6721 caaactaata aagcccagtt accaaataca ggtagtgcgg caggccaagc agcagtagca
     6781 gcaggtttag ctcttctagg tttgagtgca ggattagtag ttactaaagg taaaaaagaa
     6841 gactagaaat tttgatacct tctttatcat taaagaccaa agaaaaactc ttgtcctaaa
     6901 tagaagataa agagcctgag acaaaatagt tctcaaccac aaaaaagcta gagattccta
     6961 attgcggaac tctagctttt taattttgag tcgttctctt attgtatagt agattgaaag
     7021 tagaatagta cacttctact tctaaaacat tgttagaaat cgatttgact gtccttatcg
     7081 atttgtcctg ttcttatttc attttactat attttaggag gttattggcc ataagtacca
     7141 atcccatgtc aattctcact tgcccctcag attacatctc ttgtaaccca aagaagcctt
     7201 tatctgccca aagacaggtt ccacatcaat cttgcgttga gcgaaaatct gtctaccttg
     7261 gggagataaa agcgcctgac attctttagc tttcaagttt tgatagcgtt cgttcatata
     7321 tagtcccttt tgaggggctg attcaggttc gtcggcgtag taaaccttga tttcctgttg
     7381 aaagtctgtc tgtgttttct gatgtttggt atggtgaaaa cgataatacc agccatcagg
     7441 atgtgtgtag ctatcctcct tgtcattata gtgccaattc gctaagtttt tagctgactc
     7501 tttataccct ctcttttgtt ccttatcaaa catggcatat ttaatcagga ggggagtgat
     7561 ttcttcttga aaatagactt gtatctgttc ttgaagtttg gcggagaatt tctctgtcgt
     7621 tttcttccac acaaaactat acttgttggc attggcttca atcttagttc cgtcaataaa
     7681 caaacaatct aaggtcacta actcttccat ttttcaattt ttcgaccaga gaaaatccct
     7741 tgtgaatagg caaatagaag agtagataca agcattttaa ggtgataaga caggcgatca
     7801 aaggcatgat agaaggcgtg gaaatgacaa tcctccaagg tattcaccac tttttcaata
     7861 gtaaagacga gatggtcttg tggcaagaag gaactgattt ctagtggtaa agttgtttga
     7921 tttgtgttat agtgaatatg catgggatag cctttctaaa tggtttattg tgcaattcta
     7981 ttttaccaag actatcgcaa ccatgcaaaa aagcaacggc aaatccgttg ccttttttgg
     8041 atataagaga ctattgtccc agactctttt ctttgtataa aattgtatag tgttattgtc
     8101 tatactattt tgtagagaaa gcaaaaatcc ctagaaaatg cttagggatt cgactatttc
     8161 attaagaaca attcaacaat catctctata tacatgataa gggttaataa gaatcctgca
     8221 cgccagaaga atttgatgaa tttaggatag taaaagctgc gttttttcaa aaggaagaaa
     8281 aagacgagaa taatggctag gattgagagg gctagcccca gtctagggag gaaattatgg
     8341 gtaaaggttt tagttgtaat caagtaatac tcaaatacca agactggaaa agccaaatcc
     8401 gcaaagtttc gtcctagttt ttttaatcta aaaagtttgg ttaggataat gcagacgact
     8461 aaggtcagta tcaataataa aatagatgct aatttcatta aaatcatacc catattgtat
     8521 cataaaaaaa ggctaatgga aacgagaaac agaggaattt ataggaaagt caggcttttg
     8581 agattgtggg tgatttttgt tataatgaaa gttataaaat cttatgatac cttgaatgat
     8641 tattatcgaa aactctttgg agaaaagact tttaaagtcc ctattgatgc gggatttgac
     8701 tgtcccaatc gtgatggaac tgtggctcat ggaggctgta ctttttgtac ggtttccggt
     8761 tctggagatg ccattgtagc cccagatccg cctatccgtg agcaatttta taaggaaatt
     8821 gactttattc atcgtaagtg gccagatgtt cagaagtatc tggtttattt tcaaaatttt
     8881 accaacaccc atgaaaaggt ggaagttatt cgagagcgtt atgaacaggc tatcaatgag
     8941 ccaggtgtgg taggaatcaa tattggaacg cgcccagact gtttaccaga cgaaaccatc
     9001 gaatatttgg ctgagttatc ggagtgcatg catgtgacgg ttgaattggg cttgcagact
     9061 acttatgaag caacctctga cctgattaac cgtgcgcatt cttatgaatt gtaggtggaa
     9121 acggtcaagc gtttgagaaa gtatccaaaa attgagattg tttcccattt gatcaatggt
     9181 ttgcctggtg aaacccatga gatgatggtt gaaaatgtcc gccgttgtgt cacggataac
     9241 gatattcaag ggattaaact gcatttgctc catcttatga caaatactcg tatgcaacga
     9301 gattaccatg agggacgttt acaattgatg agtcaggacg aatatgtcag ggtcatctgt
     9361 gaccaactgg aaattattcc caaacatatc gtcatccatc gaattacagg agatgcgcct
     9421 agggatatgc tgattggtcc tatgtggagc ctcaataaat gggaagtcct caacagcatt
     9481 gagatggaga tgagacgtcg tggaagtgtt caaggatgca aggctgtaaa acaggagttt
     9541 gaaaatgaaa agaccacttg agatggcaca tgattttttg gctgaggtcg tgacaaaaga
     9601 ggatgtcgta gtggatgcga ctatgggaaa tggtcatgac acgctttttt tagccaagct
     9661 agccaagcaa gtctatgcct ttgatattca gaagcaagcc ttggaaaaga cccaagagcg
     9721 tttgcatcag gctggcttga caaatgccca gttaatcttg caaggccatg agacactgga
     9781 ccagtttgtg acaaaagcta aggcagggat ttttaatttg ggctatttgc cgtcagctga
     9841 taagtctgtc atcacccgac cgcagacaac gattgaggca ttagaaaagc tatgtggctt
     9901 acttgtcaaa ggtggacgaa ttgctattat gatttactat ggtcatgaag gaggcgacct
     9961 cgagagagat gctgtcttgg attttgtgat ccagttgaac caacaagagt acacagctgc
    10021 catttaccga actttaaacc aagtcaacaa cccgccgttt ttagtgatga ttgaaaaatt
    10081 agagagatac agacatggat aaacaatacc tacacgaaaa gctggatgcc atgcgccaga
    10141 attttgttga atcaacctac cacgaacgag cggtgggcgt gctagaccaa gcgcatatga
    10201 gcaaaaaaat gcttaaaatc aagaaaaaat tagttgctct tgaaatggaa cggtgccaga
    10261 gaaaaattga gcacaaagac tgttccaaga ttgaccaaaa aatcaaagag cagaaggaga
    10321 tatttgaatc ctgttgtaaa aaagattaag gaggacgtgc gtggaattac tgatttacct
    10381 catcctattt ttactggtct tgattgtctc aagtacaacc aataagctcc tacccttttt
    10441 gcctctccct ttggtgcaga ttcttttggg aattgtgatt ggtctctttt tacccaatac
    10501 tgactttcac cttaatacgg agttgttttt ggcactggtt atcggcccct tgcttttccg
    10561 agaggctgaa gaagcagatg ttacggctat tttaaaacac tggcgaatca ttgtttatct
    10621 catatttcca gtgattttta tctcgaccct gagtttgggt ggcttggccc atcttctttg
    10681 gttcagcctt cccttggcag cttgcttggc tgttggggca gcccttggtc ctacggactt
    10741 ggtggccttt gcctctcttt cggagcgttt tagctttcct aagcgcgtgt ccaatattct
    10801 taagggcgaa ggactcttga atgatgcttc tggtttggtg gcttttcagg tagctttgac
    10861 agcttggaca actggagctt tttctctggg gcaagctagc agttcactca tcttttcaat
    10921 cctaggcggt tttttaattg gatttttaac agccatgacc aaccgcttcc tccatacctt
    10981 cttgctaagt gtgcgtgcaa cggatattgc cagtgaactt ttattagaat tgagtttgcc
    11041 tcttgtgacc ttctttctgg cagaagaagt tcatgtttca ggtattattg ccgtcgtagt
    11101 tgctggaatt ttaaaggcaa gtcgtttcaa gaaaatcacg ctcctcgaag cccaagtgga
    11161 tacggtgacc gagacggtct ggcatacagt gacctttatg ctcaacggtt ctgtctttgt
    11221 gattttaggg atggagctgg aaatgatagc agaacctatc ttgaccaatc caatctataa
    11281 tcctctactt ttattgctat ctcttatcgc ccttaccttt gtcctctttg tcattcgttt
    11341 tattatgatc tatggctatt atgcctatag aacccgacgc ctcaagaaaa agctaaataa
    11401 gtatatgaag gacatgtttc tcttgacctt ttcaggtgtt aagggaacgg tgtcgattgc
    11461 tacgattctc ttgataccaa gtaatctaga acaggagtat cctctcttgc ttttccttgt
    11521 tgcaggtgtg acgcttgtta gctttttaac aggtctcttg gtcttgcctc atctttctga
    11581 tgaagaggaa gaaagcaagg attatctcat gcatatcgcc attttgaatg aagtaacgct
    11641 agagttggaa aaagagttgg aagacaccag aaataaactt tccctctatg cggctattga
    11701 caattatcat ggacgtattg aaaatctcat tttaagccaa gaaaaccagg atgatcaaga
    11761 agactgggct gctttgaaac tcttgattct tagtattgaa agtgatggtt tggaacaggc
    11821 ctatgaagag gggaacatta gcaatcgtgc ttaccgagtt taccaacgtt atctgaaaaa
    11881 tatagaacaa ggaatcaatc gtaaacttgc ctcaagactg acctattatt ttcttgtttc
    11941 cttgaggatt ttacgttttc tccttcatga agtttttact ctcggaaaga ccttccgtag
    12001 ctggaagaac aaggagcaaa gccgtctccg tgctcttgat tatgaccaaa ttgcagagct
    12061 ctatcttgcc aatacagaga tgattattga aagtttggaa aacctgaagg gagtctacag
    12121 acgctctttg attagtttta tgcaggagtc tcgtcttcga gaaacagcta ttatcagcag
    12181 tggtgccttt gtcgaacggg ttatcaatcg tgtcaaaccc aacaatatcg atgaaatgct
    12241 gagaggctat tatctggagc gcaagttgat tttcgaatac gaagaaaaac gattaattac
    12301 aactaagtat gccaagaaat tacgacaaaa tgtaaataac ttagagaact attccttgaa
    12361 ggaagctgcc aataccctgc cgtatgatat ggtggaattg gtaagaagaa attagttaat
    12421 actcttcgaa aatctcttca aaccacgtca gcgtcgcctt ggattatata tgtgactgac
    12481 ttcgtcagtt tcatctacaa cctcaaagca gggctttgag caacctgcgg ctagcttcct
    12541 agtttgctct ttgattttca ttgagtataa gattataaat gaaggagtat gacatgaaaa
    12601 agtggtggaa agagctgata gacaagcctt tattaaaagc ttttttgcat tattatcaag
    12661 catcagatag tgagttgacc agtgtcgcag tagcctacta ttggttgatt tcgattttcc
    12721 ccctgctttt ggtggtggtc aatatcctcc cctattttca gattcctgtg ggagaatttc
    12781 tgtgctttat gaaagacgtt ctgcccccaa gcctctatga aggtgtggaa aaaatagcca
    12841 gagaagtttt gacgcaacct tcaacaggtt tattgagttt ttctgtttta tcggcgttat
    12901 ggagtttttc aaaatctatg aatttcttgc aaaaagcttt taacaaggct tatggcgtcg
    12961 aaaagagtcg tggacttatt tcccatcaga tgctaagtct cctagtcagt tttggcttgc
    13021 agctcctctt tgcgtttgcc ttgtttttga tcttatttgg tcagatgatt ttggctttac
    13081 ttgctcatta ttggacaaaa gatggcatta tctatcaggc tttacaaggg ttggcaggtc
    13141 ctctgattta cgccctcctc tttgctatct tggtcatgct ttattatttt cttcccaata
    13201 tatctaacag gaaaattagc tataccctac caggcagtgc ctttgttctc ttagtgattt
    13261 taggtttact aactctgttc tctagttatc tcaattacta tgtccatcat ttggtggatg
    13321 tccgaatttt aggttccgtt cttcttgttg ttatgatgtt ttggtttatc ttgattgcta
    13381 aaattgttat cctaggcgcg gttatcaatg ccagtatgca gagtttgaga gatccggtct
    13441 ttaaaaaaga ctaactattt atccattaca aaagcgcata gtatcaaaac tttatagaac
    13501 cttgatacta tgcgcttttg tgctttgaca gttttttgta tagtttttgt ccaagatttc
    13561 taaatcatct gattaaattc ctattttccc ctatcattgt ccctgttttt tcgaaaatgg
    13621 aaggagtata ataaatctat caataaaatg ataggaggaa ctttatgggt catattttct
    13681 tttttctaag tgtctttttg gcagggattc tatccttctt ttctccttgt atcttacctt
    13741 tgttaccggt ctatacagga gtgttactag atgataagga tggtgctcag gcttctagcg
    13801 gcaaattttc aatctcagtt actagtttat tacgaactct ggcctttata gcaggaattt
    13861 cctttatatt tattttgttg ggctatggag ctggtttttt aggcgatttg ctttatgctt
    13921 cttggttcca atatcttact ggggcaatta ttatccttct tggtttgcac caaatggaga
    13981 ttctacactt taaggggctt tataaggaaa agaggctaca actgcaagga caggggcaaa
    14041 atggtaaggg ctatagtcag gcatttttat tgggcttgac ctttagtttt gcttggacgc
    14101 cttgcgtggg gccggttctg gggtctgttt tggccttggc ggcttcaggt ggttcaggag
    14161 cttggcaggg agctggtctc atgttggtgt atacgctggg cttggcgcta ccattcttgc
    14221 ttctagctct gacctctagt tatgttttga aacatttccg aaaacttcat ccctatctcg
    14281 gaatcctcaa aaaagtgggt ggttttctca ttattgtgat gggactcttg gttctgtttg
    14341 gaaatgcttc aattttaagt caattatttg aataaaatgg aaaggaatat caatatgaaa
    14401 aaatggcaaa catgtgttct tggagcaggt tcgctccttt gtttgacggc ttgttcaggc
    14461 aagtccgtga ctagtgaaca ccaaacgaaa gatgaaatga agacggagca gacagctagt
    14521 aaaacaagcg cagctaaagg gaaagaggtg gctgattttg aattgatggg agtagatggc
    14581 aagacctacc gtttatctga ttacaagggc aagaaagtct atctcaaatt ctgggcttct
    14641 tggtgttcca tctgtctggc tagtcttcca gatacggatg agattgctaa agaagctggt
    14701 gatgactatg tggtcttgac agtagtgtca ccaggacata agggagagca atctgaagcg
    14761 gactttaaga attggtataa gggattggat tataaaaatc tcccagtcct agttgaccca
    14821 tcaggcaaac ttttggaaac ttatggtgtc cgttcttacc caacccaagc ctttatagac
    14881 aaagaaggca agctggtcaa aacacatcca ggattcatgg aaaaagatgc aattttgcaa
    14941 actttgaagg aattagccta ggaggtgtct tatgaatgat aagttaaaaa tcttcttgtt
    15001 gctaggagta ttttttctag ccataaccgg tttctatgtt ctattgatac gaaatgcagg
    15061 gcagacagat gcctcgcaaa ttgaaaaggc ggcagttagc caaggaggaa aagcagtgaa
    15121 aaaaacagaa attagtgaag acgcagactt gcacgaaatt tatctagctg gaggttgttt
    15181 ctggggagtg gaggaatatt tctcacgcgt tcccggggtg acggatgccg tttcaggcta
    15241 tgcaaatggt agaggagaaa caaccaagta cgaattaatt aaccaaacag gtcatgcaga
    15301 aaccgtccat gtcacctatg atgccaagca aatttctctc aaggaaatcc tgcttcacta
    15361 tttccgcatt atcaatccaa ccagcaaaaa taaacaagga aatgatgtgg ggacccagta
    15421 ccgtactggt gtttattaca cagatgacaa ggatttggaa gtgattaacc aagtctttga
    15481 tgaggtggct aagaaatacg atcaacctct agcagttgaa aaggaaaact tgaagaattt
    15541 tgtggtggct gaggattacc atcaagacta tctcaagaaa aatccaaatg gctactgcca
    15601 tatcaatgtt aatcaggcgg cctatcctgt cattgatgcc agcaaatatc caaaaccaag
    15661 tgatgaggaa ttgaaaaaga ccctgtcacc tgaggagtat gcagttaccc aggaaaatca
    15721 aacagaacga gctttctcaa accgttactg ggataaattt gaatccggta tctatgtgga
    15781 tatagcaact ggggaacctc tcttttcatc aaaagacaaa tttgagtctg gttgtggctg
    15841 gcctagtttt acccaaccca tcagtccaga tgttgtcacc tacaaggaag ataagtccta
    15901 caatatgacg cgtatggaag tgcggagccg agtaggagat tctcaccttg ggcatgtctt
    15961 tacggatggt ccacaggaca agggcggctt acgttactgt atcaatagcc tctctatccg
    16021 ctttattccc aaagaccaaa tggaagaaaa aggctacgct tatttactag attatgttga
    16081 ttaatactct tcgaaaatct cttcaaacca cgtcagcgtc gccttaccgt atgtagggtt
    16141 actgacttcg tcagttttat ctacaacctc aaagct
//
LOCUS       DAVHTH010000046        15676 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.046, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000046 DAVHTH010000000
VERSION     DAVHTH010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15676)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15676)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15676
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.046"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            <1..1033
                     /gene="phtB"
                     /locus_tag="VVR63_001549"
     CDS             <1..1033
                     /gene="phtB"
                     /locus_tag="VVR63_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtB"
                     /protein_id="HEU6129553.1"
                     /translation="LKDVSSDKVKLVDDILAFLAPIRHPERLGKPNAQITYTDDEIQV
                     AKLAGKYTTEDGYIFDPRDITSDEGDAYVTPHMTHSHWIKKDSLSEAERAAAQAYAKE
                     KGLTPPSTDHQDSGNTEAKGAEAIYNRVKAAKKVPLDRMPYNLQYTVEVKNGSLIIPH
                     YDHYHNIKFEWFDEGLYEAPKGYTLEDLLATVKYYVEHPNERPHSDNGFGNASDHVQR
                     NKNGQADTNQTEKPSEEKPQTEKPEEETPREEKPQSEKPESPKPTEEPEEESPEESEE
                     PQVETEKVEEKLREAEDLLGKIQDPIIKSNAKETLTGLKNNLLFGTQDNNTIMAEAEK
                     LLALLKENK"
     gene            1452..1826
                     /locus_tag="VVR63_001550"
     CDS             1452..1826
                     /locus_tag="VVR63_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002960428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
                     /protein_id="HEU6129554.1"
                     /translation="MESIGLVIVSHSKHIAEGVVELISKVAKDVPITYVGGTEGGGIG
                     TSFNQVDRVVSENPADTLLAFFDLGSAKMNLKMVTDFSDKSIIINRVPIVEGAYNAAA
                     LLQAGAELSVIQTQLAELEINK"
     gene            2285..2998
                     /locus_tag="VVR63_001551"
     CDS             2285..2998
                     /locus_tag="VVR63_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HEU6129555.1"
                     /translation="MFYKFLLFDLDHTLLDFDAAEDVALTQLLKEEGVADIQAYKDYY
                     VPMNKALWKDLELKKISKQELVNTRFSRLFSHFGQEKDGSFLAQRYQFYLAQQGQTLS
                     GAHDLLDSLIERDYDLYAATNGITAIQTGRLAQSGLVPYFNQVFISEQLQTQKPDALF
                     YEKIGQQIAGFSKENTLMIGDSLTADIQGGNNAGIDTIWYNPHHLENHTQAQPTYEVY
                     SYQDLLDCLDKNILEKITF"
     gene            3012..3659
                     /locus_tag="VVR63_001552"
     CDS             3012..3659
                     /locus_tag="VVR63_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6129556.1"
                     /translation="MTTKKANITIEEYIEMSEVDFNEAVNYEFTSDTCQLANSIYQSL
                     FKFFDKKNFSGDLIFTWKSPSLVKEGDYIGRRDSQVDNLRVIGNIFPNYLTNRKYSLN
                     MNRNGCIGDFPHDFFDTYLDHVAKYAYEQKVNNIKEYYPLKRAILHQENALYFRLFSN
                     FDDFLEKNYLKTIWQVSKETPFSEMDFNMFKNISEKIIFERGSKMLNDLKSNYKK"
     gene            3795..4448
                     /locus_tag="VVR63_001553"
     CDS             3795..4448
                     /locus_tag="VVR63_001553"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HEU6129557.1"
                     /translation="MEHSSWHALIKAQLPEGYFGKINQFMEQVYSQGIIYPPKEKVFQ
                     ALLTTLLEEVKVVILGQDPYHGPGQAQGLSFSVPDSIPAPPSLQNILKELSDDIGVKK
                     SHDLTAWAEQGVLLLNACLTVPAGQANGHAGQIWEPFTDAVIQVVNHLDRPVVFVLWG
                     AYARKKKALVTNPHHLIIESAHPSPLSVYRGFWGSKPFSKANAFLKETGQEPIDWLR"
     gene            4458..4922
                     /locus_tag="VVR63_001554"
     CDS             4458..4922
                     /locus_tag="VVR63_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003012002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEU6129558.1"
                     /translation="MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGE
                     TPQECATREILEETGLKAKPVLKGVITFPEFTPDLDWYTYVFKVTEFEGDLIDCNEGT
                     LEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE"
     gene            4935..6203
                     /locus_tag="VVR63_001555"
     CDS             4935..6203
                     /locus_tag="VVR63_001555"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HEU6129559.1"
                     /translation="MLLIKNGRVMDPKSGLDQVCDVLVQDGKIIKIAPEITEEGAETI
                     DATGLVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGFTTVVMMANTSPTISDVE
                     TLQAVLQSAAKEKINVKTVATITKNFNGKNLTDFKALLEAGAVGFSDDGIPLESSKIV
                     KEAMEEAKKLNTFISLHEEDPGLNGVLGFNENIAREHFHICGATGVAEYAMMARDVMI
                     AYATKAHVHIQHLSKEESVKVVEFAQGLGAEVTAEVAPQHFSKTEALLLTQGSNAKMN
                     PPLRLESDRRAVIEGLKSGVITVIATDHAPHHVDEKNVEDITKAPSGMTGLETSLSLG
                     LTYLVEAGELSLMELLEKMTYNPAKLYNFKAGYLAENGPADITIFDAKADRLVDSHFA
                     SKAANSPFIGETLKGQVKYTICKGQIVYQA"
     gene            6217..6477
                     /locus_tag="VVR63_001556"
     CDS             6217..6477
                     /locus_tag="VVR63_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6129560.1"
                     /translation="MNYFRKRRERQAKSNSGIYCPAANRSKIQYETKEKADHAVQYDN
                     GGLVRSYYCRTCACWHTTSKSNKPPLSLKNYGLKLFGLDKSE"
     gene            6488..7849
                     /gene="pdrM"
                     /locus_tag="VVR63_001557"
     CDS             6488..7849
                     /gene="pdrM"
                     /locus_tag="VVR63_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-coupled multidrug efflux MATE transporter
                     PdrM"
                     /protein_id="HEU6129561.1"
                     /translation="MYKTKCLREKLVLFLKIFFPILIYQFANYSASFVDTAMTGQYNT
                     MDLAGVSMATSIWNPFFTFLTGIVSALVPIIGHHLGRGKKEEVASDFYQFIYLALGLS
                     VVLLGMVLFLAPTILNHIGLEAAVAAVAVRYLWFLSIGIIPLLLFSVIRSLLDSLGLT
                     KLSMYLMLLLLPLNSGFNYLLIYGAFGVPELGGAGAGLGTSLAYWVLLGISVLVLFKQ
                     EKLKALHLEKRIPLNMDKIKEGVRLGLPIGGTVFAEVAVFSVVGLIMAKFSSLIIASH
                     QSAMNFSSLMYAFPMSISSAMAIVVSYEVGAKRFDDAKTYIGLGRWTALIFAAFTLTF
                     LYIFRGNVASLYGNDPKFIDLTVRFLTYSLFFQLADTFAAPLQGILRGYKDTVIPFYL
                     GLLGYWGVAIPVATLFDSLTDFGAYSYWIGLIISLIVSGALYRWRLTVIMKRFESLAK
                     SKR"
     gene            8003..8971
                     /locus_tag="VVR63_001558"
     CDS             8003..8971
                     /locus_tag="VVR63_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HEU6129562.1"
                     /translation="MSTLDKNLLLEMFRKMEEIRRMDLKIAQLVKKGKVPGMTHFSVG
                     EEAANVGAMLALNPDDLITSNHRGHGQAIAKGIDLNGMMAEILGKYTGTCKGKGGSMH
                     IADLDAGNLGANGIVGGGMGIAVGAALSQQMQNTGKIVVCFFGDGATNEGVFHEAVNM
                     ASIWNLPVIFYCINNGYGISADIKKMTNIEHIHQRSAAYGIPGMFIEDGNNVIDVYEG
                     FQKAVDHVRSGNGPVLIESVTYRWLGHSSSDPGKYRTREEVELWKQKDPIENLRNYLI
                     ENNIASAEELEKIQAQVKEAVEASVKFAEESPFPPLESAFEDIYTD"
     gene            8987..9979
                     /locus_tag="VVR63_001559"
     CDS             8987..9979
                     /locus_tag="VVR63_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HEU6129563.1"
                     /translation="METKTMSFRDTIILAMSEEMRRDENVFLMGEDVGVFGGDFGTSV
                     GMLEEFGPERVRDCPISEAAISGAAAGAAMTGLRPIVDMTFMDFSVIAMDNIVNQAAK
                     TRYMFGGKGQVPMTVRCAAGNGVGSAAQHSQSLESWFTHIPGLKVVAPGTPADMKGLL
                     KSSIRDNNPVIILEYKSEFNQKGEVPVDPDYTIPLGVGEIKRQGTDVTVVTYGKMLRR
                     VVQAAEELAEEEISVEIVDPRTLVPLDKDIIINSVKKTGKVILVNDAHKTSGYIGEIS
                     AIISESEAFDYLDAPIRRCSGEDVPMPYAQNLENAMIPTVESIKDAIRKTYNKD"
     gene            10197..11240
                     /locus_tag="VVR63_001560"
     CDS             10197..11240
                     /locus_tag="VVR63_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HEU6129564.1"
                     /translation="MADDKLRATPAARKLADDLGINLYDVSGSGANGRVHKEDVETYK
                     DTNVVRISPLAKRIALEHNIAWQEIQGTGHRGKIMKKDVLALLPENIENDSIKSPAQI
                     EKVEEVPDNVTPYGEIERIPMTPMRKVIAQRMVESYLTAPTFTLNYEVDMTEMLALRK
                     KVLEPIMEATGKKTTVTDLLSLAVVKTLMKHPYINASLTEDGKTIITHNYVNLAMAVG
                     MDNGLMTPVVYNAEKMSLSELVVAFKDVIGRTLDGKLAPSELQNSTFTISNLGMFGVQ
                     SFGPIINQPNSAILGVSSTIEKPVVVNGEIVIRPIMSLGLTIDHRVVDGMAGAKFMKD
                     LKELIETPISMLI"
     gene            11304..12989
                     /gene="lpdA"
                     /locus_tag="VVR63_001561"
     CDS             11304..12989
                     /gene="lpdA"
                     /locus_tag="VVR63_001561"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HEU6129565.1"
                     /translation="MPKAGVDMTEGQIVQWNKKVGEFVKEGEILLEIMTDKVSMELEA
                     EEDGYLIAILKGDGETVPVTEVIGYLGEERENIPTAGAASPEASPVPVASTSNDDGKS
                     DDAFDIVVIGGGPAGYVAAIKAAQLGGKVALVEKSELGGTCLNRGCIPTKTYLHSAEI
                     IENIGHAANRGIVIENPNFTVDMEKLLETKSKVVNTLVGGVAGLLRSYGVAVHKGIGT
                     ITKDKNVLVNGSELLETKKIILAGGSKVSKINVPGMESPLVMTSDDILEMNEVPESLV
                     IIGGGVVGIELGQAFMTFGSKVTVIEMMDRIVPAMDVEVSKNLRLILERKGMTILTGT
                     KLQEIIEENGQLRIKVEGKDDIIASKALLSIGRMPDLEGIGEVEFELDRGCIKVNEYM
                     ETSVPGIYAPGDINGTKMLAHAAFRMGEVSAENALKGNHAVAKLNLTPAAIYTLPEVA
                     AVGLTEEQAREKYDVAIGKFNFAANGRAIASDAAQGFVKVIADKKYGEILGVHIIGPA
                     AAELINEASSIIEMEITVEEMLKTIHGHPTYSEVMYEAFADVLGMAIHSPKKK"
     gene            13053..14042
                     /locus_tag="VVR63_001562"
     CDS             13053..14042
                     /locus_tag="VVR63_001562"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000873976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HEU6129566.1"
                     /translation="MKYIINHSNDTAFNIALEEYAFKHLLDEDQIFLLWINKPSIIVG
                     RHQNTIEEINRDYVRENGIEVVRRISGGGAVYHDLNNLNYTIISKEDENKAFDFKSFS
                     TPVINTLAQLGVKAEFTGRNDLEIDGKKFCGNAQAYINGRIMHHGCLLFDVDLSVLAN
                     ALKVSKDKFESKGVKSVRARVTNIINELPKKITVEKFRDLLLEYMKKEYPEMTEYVFS
                     EEELAEINRIKDTKFGTWDWNYGKSPEFNVRRGTKFTSGKVEVFANVTESKIQDIKIY
                     GDFFGIEDVAAVEAVLRGVKYEREDVLKALKTIDITRYFAGISREEIAEAVVG"
     gene            complement(14107..15177)
                     /gene="xerS"
                     /locus_tag="VVR63_001563"
     CDS             complement(14107..15177)
                     /gene="xerS"
                     /locus_tag="VVR63_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HEU6129567.1"
                     /translation="MKREILLERIDKLKQLMPWYVLEYYQSKLAVPYSFTTLYEYLKE
                     YDRFFSWVLESGISNADKISDIPLSVLENMSKKDMESFILYLRERPLLNANTTKQGVS
                     QTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAENIKQK
                     LFLGDETEGFLTYIDQEHPQQLSNRALSSFNKNKERDLAIIALLLASGVRLSEAVNLD
                     LRDLNLKMMVIDVTRKGGKRDSVNVAAFAKPYLENYLAIRNQRYKTEKTDTALFLTLY
                     RGVPNRIDASSVEKMVAKYSEDFKVRVTPHKLRHTLATRLYDATKSQVLVSHQLGHAS
                     TQVTDLYTHIVSDEQKNALDSL"
BASE COUNT         4814 a         2835 c         3384 g         4643 t
ORIGIN      
        1 actcaaggat gtctcaagtg ataaagtcaa gttagtggat gatattcttg ccttcttagc
       61 tccgattcgt catccagaac gtttaggaaa accaaatgcg caaattacct acactgatga
      121 tgagattcaa gtagccaagt tggcaggcaa gtacacaaca gaagacggtt atatctttga
      181 tcctcgtgat ataaccagtg atgaggggga tgcctatgta actccacata tgacccatag
      241 ccactggatt aaaaaagata gtttgtctga agctgagaga gcggcagccc aggcttatgc
      301 taaagagaaa ggtttgaccc ctccttcgac agaccatcag gattcaggaa atactgaggc
      361 aaaaggagca gaagctatct acaaccgcgt gaaagcagct aagaaggtgc cacttgatcg
      421 tatgccttac aatcttcaat atactgtaga agtcaaaaac ggtagtttaa tcatacctca
      481 ttatgaccat taccataaca tcaaatttga gtggtttgac gaaggccttt atgaggcacc
      541 taaggggtat actcttgagg atcttttggc gactgtcaag tactatgtcg aacatccaaa
      601 cgaacgtccg cattcagata atggttttgg taacgctagt gaccatgttc aaagaaacaa
      661 aaatggtcaa gctgatacca atcaaacgga aaaaccaagc gaggagaaac ctcagacaga
      721 aaaacctgag gaagaaaccc ctcgagaaga gaaaccgcaa agcgagaaac cagagtctcc
      781 aaaaccaaca gaggaaccag aagaagaatc accagaggaa tcagaagaac ctcaggtcga
      841 gactgaaaag gttgaagaaa aactgagaga ggctgaagat ttacttggaa aaatccagga
      901 tccaattatc aagtccaatg ccaaagagac tctcacagga ttaaaaaata atttactatt
      961 tggcacccag gacaacaata ctattatggc agaagctgaa aaactattgg ctttattaaa
     1021 ggagaataag taaaggtagc agcattttct aactcctaaa aacaggatag gagaacggga
     1081 aaacgaaaaa tgagagcaga atgtgagttc tagttctcat ttttttatga aaatgtgcaa
     1141 aatatagtag attgaaatta gaatagtata cctctacttc taaaacattg ttagaaatcg
     1201 atttgactgt cctgttctta tttcatttta ctatatctta acagatagtg taaataaaga
     1261 taaactattt actggctaat taatcagtta aacactagtt aaggagtaat gataaaaaag
     1321 aacaatacta ttattgatgg ccagtctgtt ggctcttgtc ttaggagcat gtggtttttt
     1381 ggacatatcg atcctggatc attctcatca ggattactat ttactgctat tttagaaact
     1441 ggggtggttt gatggaaagt attggtcttg ttatcgtttc acattccaaa cacattgcag
     1501 aaggtgttgt tgaactgatt agtaaagtag ctaaagatgt tccgattact tatgtaggag
     1561 gaaccgaggg cggaggaatt ggaacgagtt ttaatcaagt agatagggtt gtttccgaaa
     1621 atccagcaga tactttactt gccttttttg acctaggttc tgctaaaatg aacttaaaaa
     1681 tggtgactga tttcagtgat aaaagtatca tcatcaacag ggttccaatt gtagaaggtg
     1741 cctataatgc agctgctctt cttcaggctg gtgcagaact gtcagttatt caaacacagt
     1801 tagcggagct tgaaatcaat aaataaggaa ttttactata actcttttta taggtaagct
     1861 attgattatc tcaactataa aatgttaagt aaatgatttc aaaatcagaa agggattgct
     1921 ttatgcagtt cctttttatt ttaacaggag tgaaactata gtgtttctaa attgtgaatc
     1981 aatcaaaact gattgtgatg gggctattct agctttagaa tccttcaaaa attaaaattt
     2041 aaggcaatca attacttgga agagtatgaa agcatttagt ttataggaat tctaggccta
     2101 gaattacata tgtatttatg aagacggggt gttcgatagt tagtattgtt ctattctgaa
     2161 agatttgagc tgtcagttgt atagaaagtg ttcgaatttt ttttaagtga ttaaattagt
     2221 taattgtatg aggtgcttta tgatataatg ttcttaatga attttcagaa aggaaaacct
     2281 caaattgttc tacaaatttc tactcttcga cctcgaccac actcttcttg attttgatgc
     2341 tgctgaggat gtggctttga cccaacttct aaaagaagaa ggagttgcgg atattcaggc
     2401 ttataaagat tattacgttc ctatgaacaa ggctctctgg aaagacttgg agctgaagaa
     2461 aatcagtaaa caagagctgg ttaacacgcg cttttctcgt ttattttctc attttggaca
     2521 ggaaaaagac ggtagttttc ttgcccagcg ttaccaattt tatctcgctc agcagggaca
     2581 aacactatcg ggcgctcatg atctcttgga cagcctcatt gagcgtgatt atgacttgta
     2641 tgctgcgaca aatggcatta ctgccattca gacaggacgt ttggctcaat ctggtctagt
     2701 accttatttc aatcaagtct ttatctcaga acagttgcaa actcaaaagc cggatgctct
     2761 cttttatgaa aagattggcc agcaaattgc tggatttagt aaagaaaata cgctgatgat
     2821 tggagattct ctaaccgccg acattcaagg tggcaataat gcggggattg acactatctg
     2881 gtataatcct catcacctcg aaaatcacac acaagcccag ccgacttacg aagtctattc
     2941 ttaccaagac ttgctggatt gtttagataa aaatattctt gaaaagatca cattttaaag
     3001 gagattagct aatgactaca aaaaaagcta atattactat tgaagagtac attgaaatgt
     3061 ctgaagttga ttttaatgaa gctgttaatt atgaatttac atctgacact tgtcaattag
     3121 caaatagtat ttatcaatct ctttttaagt tttttgataa gaaaaatttc tctggcgatt
     3181 taatttttac ttggaaatct ccatcattag tcaaagaagg ggattatatt gggagaaggg
     3241 attcacaagt agataatctt agagtaatag gaaatatatt tccgaattat cttactaatc
     3301 gaaaatatag cctcaatatg aatcgtaatg gctgtatagg agattttcct catgactttt
     3361 ttgatacata cctagatcat gtagcaaaat atgcctacga acaaaaagtt aataatatta
     3421 aagagtatta tcctttaaaa agagcgattt tacaccaaga gaatgcattg tattttcgat
     3481 tgttttctaa ttttgatgac tttttagaaa aaaattattt aaagactata tggcaagttt
     3541 ctaaagaaac tcctttttct gaaatggatt ttaatatgtt taaaaatatt tcagaaaaga
     3601 taatcttcga aagaggtagt aaaatgctta atgatttaaa aagtaattat aaaaaatagc
     3661 cagtctttat aaactgtatt cacgtattca aatcgtatat agtcgattta ttaaatcttt
     3721 agataaattg taaaaagtgg tttccatagc cactttttgc tataatagag gcagtaaaaa
     3781 tgaaggagtc agctatggaa cactcgtctt ggcatgcttt gattaaggcg caattacctg
     3841 agggttattt cgggaaaatc aatcagttta tggagcaggt ctattctcag gggattattt
     3901 atccacccaa ggaaaaggtt tttcaggctc tcttgacaac actgcttgaa gaagttaagg
     3961 tggtaattct agggcaagac ccctatcacg gaccaggtca agcgcagggc ttgagttttt
     4021 ctgtacctga ctctatccca gctccaccat ccttgcaaaa tatcttgaaa gaattgtcag
     4081 atgatatcgg agttaagaaa tctcatgatt tgacagcttg ggctgagcaa ggagtcttgc
     4141 ttcttaatgc ttgtttgact gttcctgctg gacaggccaa tggtcatgct ggtcaaatct
     4201 gggagccttt tactgatgct gtgattcagg tggtcaatca tctagataga ccagtcgttt
     4261 ttgtactctg gggagcttat gcacgtaaga agaaggcctt agttaccaat cctcatcact
     4321 tgattatcga atcagcccat ccaagtcctt tgtcggttta tagaggattt tggggttcca
     4381 agcccttttc caaggccaat gcattcttaa aagagacagg acaagagcca atcgattggc
     4441 ttagataagg agaaaatatg cctcagttag cgacgatttg ctacattgat aatgggaaag
     4501 aactgctcat gctccatcgt aataagaaac ccaatgatgt ccatgaaggg aaatggattg
     4561 gtgtgggtgg taagctagag agaggagaga cgccccagga atgcgcgacg cgtgaaatcc
     4621 ttgaagaaac agggctcaaa gccaagccag ttctaaaagg tgtcatcact tttcctgaat
     4681 ttacaccaga tttagactgg tacacctatg tttttaaggt gacggagttt gagggcgact
     4741 tgattgactg caatgagggg acgctagaat gggttcccta tgatgaggtt ttgagcaagc
     4801 cgacttggga aggtgaccac acctttgttg agtggctttt agaggataaa cccttctttt
     4861 cagccaagtt tgtttatgat ggggataaat tgttggatac ccaagttgat ttctatgaat
     4921 aaaggagaaa gcagatgcta ctaatcaaaa atggtcgtgt aatggatccc aagtctggtt
     4981 tggatcaagt ttgtgatgtc ttagttcaag atgggaaaat tatcaaaatt gcgcctgaga
     5041 tcacggaaga aggagcagaa acgattgatg ctactggtct tgtggttgct cctggtttgg
     5101 tcgatattca tgtgcatttc cgtgaacctg gtcaaacaca taaagaagac attcatactg
     5161 gtgccctagc agccgctgca ggtggtttta ctactgtcgt catgatggct aataccagtc
     5221 caaccatttc agacgtggag actttgcaag cagttctcca gtcagctgcc aaagagaaga
     5281 ttaatgtcaa gacagttgcg accattacta aaaactttaa tggtaaaaac ttgactgact
     5341 ttaaggcact cttagaagct ggtgcggttg gtttctctga tgacggtatt ccgcttgaga
     5401 gcagtaagat tgtcaaggaa gccatggagg aagccaaaaa actcaatacc tttatcagcc
     5461 ttcatgagga agatccaggt ttgaacggtg ttcttggctt taatgaaaat attgctagag
     5521 aacatttcca tatctgcggt gctactgggg tggctgagta cgctatgatg gcgcgtgatg
     5581 tcatgattgc ctatgcaact aaagcccatg ttcacatcca gcatttgtct aaggaagaaa
     5641 gtgttaaagt agtggagttt gctcaggggt taggtgcaga agtcacagca gaagtagcgc
     5701 cacagcattt ctctaagaca gaagcacttc ttttaacaca aggtagcaat gctaagatga
     5761 atccaccgct tcgtttggaa tcagaccgtc gtgccgttat cgaaggtctc aaatcaggtg
     5821 tcatcacagt tattgcgact gaccacgcgc ctcatcatgt agatgaaaaa aatgttgagg
     5881 atattaccaa agcgccatct ggtatgactg gcttagaaac atccctgtct ctcggcttga
     5941 cctatttggt agaagctggt gagttgagct tgatggaatt acttgaaaaa atgacataca
     6001 acccagccaa gctttacaac tttaaagcag gttacttggc tgagaatggt ccagcagata
     6061 tcactatttt tgatgccaag gctgaccgcc ttgtggactc ccattttgct tccaaagcag
     6121 ctaattcacc attcatcggt gaaaccttaa aagggcaggt taaatatacc atctgtaagg
     6181 gacaaatcgt ctatcaagct tgataggagt tagaatatga attattttcg aaaacgtagg
     6241 gagagacaag cgaaatctaa tagtggaatt tactgtcctg cagctaatcg ttccaaaatt
     6301 caatatgaaa ctaaagaaaa agctgaccat gcggttcaat atgataacgg aggtttagtt
     6361 agaagctatt attgtcgtac atgtgcgtgt tggcatacta cttcaaaatc taataaacct
     6421 ccgctaagtt tgaaaaacta tggtctgaaa ctctttggtt tagataaatc agaatagaaa
     6481 gagaagtatg tataagacaa agtgtttacg agagaagttg gtattatttt taaaaatttt
     6541 cttcccaatc ctgatttacc aatttgccaa ttattctgcc tcttttgttg atactgcaat
     6601 gacaggtcaa tacaacacta tggacttggc tggtgtatct atggcaacca gtatctggaa
     6661 tcctttcttt acatttctaa cagggattgt gtcagccttg gtgcctatca ttggtcacca
     6721 tcttggtcga ggaaaaaagg aagaagttgc gtctgatttt taccaattta tttatttggc
     6781 cttgggccta tctgtggtct tgctggggat ggtacttttc ttggcaccaa caatcttgaa
     6841 tcatattggg ttagaagcag cagtagcggc agtagcggtt cgctatcttt ggtttttatc
     6901 tatcgggatt atccccttgt tgctctttag cgtcattcgt tccttgctgg attcgctggg
     6961 cttgaccaaa ctgtccatgt acctcatgct tttgttactc cctctcaata gcggatttaa
     7021 ctatctcttg atttacggtg cctttggtgt tccagaactg ggaggggctg gtgctggttt
     7081 aggaacatcc ttggcctact gggtcttgct tgggatttct gttctggttt tatttaaaca
     7141 ggagaagctc aaagccttac accttgagaa acgaattcca cttaatatgg ataaaattaa
     7201 ggaaggagtt cgtttaggtc tgcctattgg gggaactgtc ttcgcggaag tggctgtctt
     7261 ttcagtggtt ggcttgatta tggctaagtt ttcgtccttg attatagcta gtcaccagtc
     7321 agctatgaac ttttcaagtc ttatgtacgc ctttcctatg agtatctcat cggctatggc
     7381 tattgtcgtt tcctatgaag tgggagccaa gcgatttgat gatgcgaaaa cctatattgg
     7441 tctaggaaga tggactgccc tcatttttgc ggccttcacc ttaaccttcc tttacatttt
     7501 taggggaaat gtggccagtc tttatggtaa cgacccaaaa tttatcgatt tgacagtgcg
     7561 ttttttaact tatagtcttt tcttccagtt agcagatacc tttgcggcgc cgcttcaggg
     7621 aattttgcgg gggtataagg atacagttat tcctttttac cttggtttgc ttggttattg
     7681 gggcgtagca atccctgtgg ctacgctatt tgattcccta acagattttg gagcttattc
     7741 ttactggatc ggcttgatta ttagtttgat tgtgagcggg gcgctctacc gttggcgttt
     7801 aactgtgatt atgaagagat ttgaatcttt agcaaaatcc aaacgctaaa aagtttgtga
     7861 aaaaatattc ttgacaagaa aatcccttgt tttcacgggg ttttcttttt tattttgtga
     7921 aatttctttt agaaaaactt tgacagtatt tgccaaaagc ggtaaaatag taaggtaaga
     7981 agaaagttag aaaggcaaga agatgtcaac tttagataaa aatcttttgc tagaaatgtt
     8041 ccgtaagatg gaagaaatcc gtcgcatgga cttaaaaatt gcacaattag taaagaaagg
     8101 gaaagtgcca ggaatgacgc acttttctgt tggtgaagag gcagctaacg tgggggctat
     8161 gttagctctc aatccagatg atctgattac ctcaaaccac cgtggacacg ggcaagctat
     8221 tgctaaaggg attgacctca acggaatgat ggctgaaatc cttggtaaat acactggaac
     8281 ctgtaaaggg aaaggtggat ctatgcatat cgctgacctt gatgctggga accttggtgc
     8341 caatggtatc gtaggtggtg gtatggggat cgctgtcggt gcagccctca gtcagcaaat
     8401 gcaaaatacc ggtaaaatcg ttgtttgctt ctttggagat ggtgcgacca atgaaggtgt
     8461 tttccacgaa gcagtgaaca tggcttctat ctggaacctg ccagtcattt tctattgcat
     8521 taacaacggt tacggtatct ctgcggatat caagaaaatg accaatatag aacatatcca
     8581 tcaacgtagc gccgcttatg gaattcctgg aatgttcatc gaagacggta acaatgtcat
     8641 cgatgtctat gaaggatttc agaaagctgt agaccatgtt cgcagtggca atggtccagt
     8701 cttgattgaa agtgtaactt atcgctggct tggtcactca tcatctgacc ctggtaaata
     8761 tcgtacgcgt gaagaagtgg aattgtggaa acaaaaagat ccaatcgaaa acctccgcaa
     8821 ttaccttatt gaaaataaca ttgcaagtgc cgaagaattg gaaaaaatcc aagcgcaagt
     8881 aaaggaagca gtagaagctt ctgttaaatt tgcagaggaa agcccattcc caccgcttga
     8941 atcagccttt gaagatattt acacagacta aggagaaaga gataaaatgg aaacaaaaac
     9001 aatgtccttc cgtgacacca ttatccttgc tatgtctgag gaaatgcgtc gcgatgaaaa
     9061 tgtgttcttg atgggagaag atgtcggtgt cttcggagga gacttcggta cttctgttgg
     9121 aatgcttgaa gaatttggtc cagaacgtgt ccgtgactgt ccgatttctg aagctgccat
     9181 ctctggagca gcagcaggag cagccatgac aggacttcgt ccaatcgtcg atatgacctt
     9241 catggacttc tctgttattg ccatggacaa tatcgtcaac caagctgcta aaacacgtta
     9301 catgtttggt ggtaaaggtc aggttccaat gactgttcgt tgtgcagctg gtaacggagt
     9361 tggctctgcc gcccagcact cacaatctct agagtcttgg tttactcaca ttccaggact
     9421 taaggttgtg gcacctggaa cacctgcgga catgaaaggc ctgcttaagt cttctatccg
     9481 tgataacaac ccagttatta tacttgagta caagtcagaa tttaaccaaa aaggggaagt
     9541 gccagttgat ccagactaca caattccact tggggttggt gaaatcaaac gccaaggaac
     9601 ggatgtaaca gttgttactt atggaaaaat gcttcgccgt gtggttcaag ctgctgaaga
     9661 attagcagaa gaagaaattt cagttgaaat tgttgaccca cgtacccttg ttccgcttga
     9721 taaggatatc atcataaact cagtgaagaa gactggtaag gttattctgg tcaacgatgc
     9781 ccacaaaaca agtggctata tcggtgaaat ttcagctatt atttcagaat cagaagcatt
     9841 tgactatcta gatgcaccaa tacgccgttg ttcaggagaa gatgtgccga tgccttatgc
     9901 acaaaaccta gaaaatgcaa tgattccaac agttgaaagt atcaaagatg caatccgaaa
     9961 aacttataat aaagactaga gttacataat ataagttatg taactaaaat aaagctgacg
    10021 agaaactttg tatcttttag gtgcagagct cttcgtcatt aatatcttat attcgagcac
    10081 gggctaaaag ctcggaaaaa agataaatct ccttggcttc atcgaagcca tcgtcgattt
    10141 cctatttttc agtcgctttt gacgcccttt gtatcataaa tagaattgga gaggtcatgg
    10201 ctgatgacaa gctaagagcg actcctgcag ctagaaagtt agcggatgat ttagggataa
    10261 acctctacga cgtttctggc tcaggtgcaa acggtcgtgt ccacaaagaa gacgtggaaa
    10321 cttataaaga cacaaacgtg gttcgcattt cgccacttgc aaaacgaatt gccctcgaac
    10381 ataacattgc ttggcaggaa atccaaggaa ccggtcatcg tggtaaaatc atgaagaagg
    10441 atgttttggc cctgcttcct gaaaatatcg aaaacgatag catcaaatct cctgctcaga
    10501 ttgaaaaagt ggaagaagtc cctgataacg taacaccata tggtgaaatc gagcgtattc
    10561 caatgacacc aatgcgtaag gttattgccc aacgcatggt tgaatcttac ttgactgcgc
    10621 caaccttcac cctcaactat gaagttgata tgactgaaat gttggctctt cgtaagaagg
    10681 ttcttgagcc aatcatggaa gcaactggga agaagactac tgtaacagac cttctttcgc
    10741 ttgcagttgt taagactctt atgaaacacc catacatcaa tgcttcattg acagaagatg
    10801 gcaagactat tatcactcac aactatgtca atcttgccat ggcagttggg atggataatg
    10861 gattgatgac acctgttgtt tacaatgctg agaagatgag tctttcagaa ctggttgtag
    10921 cctttaagga tgttattggc cgtaccttgg atggtaaatt ggctccaagt gagttacaaa
    10981 attcaacatt cacaatcagt aatttgggaa tgtttggtgt tcagtccttt ggcccgatta
    11041 ttaaccaacc caactcagct atccttggtg tcagttcgac aatcgagaag ccagttgtcg
    11101 tcaatggtga aattgtgatt cgcccaatca tgagtttagg attaaccatt gaccaccgtg
    11161 tcgtagatgg tatggctggt gctaagttta tgaaggactt gaaagagttg attgaaaccc
    11221 caatctcaat gttgatttaa gagcaagagt attcattttt aagatataga taaaggaagg
    11281 aagacatggc cttagaagta attatgccaa aagccggcgt ggatatgaca gaaggacaaa
    11341 tcgtccaatg gaataaaaaa gtcggagaat ttgtaaaaga aggagaaatc cttttggaaa
    11401 tcatgactga taaagtcagc atggaattgg aagccgaaga agatgggtac ttgattgcca
    11461 ttctcaaagg agatggtgaa actgtccctg taacggaagt tatcggttac cttggtgaag
    11521 aaagggaaaa catcccaaca gctggagcag catcgccaga agctagccct gtacctgtag
    11581 caagtacctc aaacgatgat ggtaagagcg atgatgcttt tgatatcgtt gtgattggtg
    11641 gaggtcctgc tggttatgtt gcagccatta aagctgccca actcggcggt aaggttgccc
    11701 ttgttgagaa atctgaactt ggtggaacct gcttaaaccg tggatgtatt ccaaccaaga
    11761 cctaccttca tagcgctgaa attattgaaa atatcggtca tgctgcaaat cgtggtatcg
    11821 tgattgaaaa tcctaacttc actgttgata tggaaaaact tttagaaact aaatctaaag
    11881 ttgttaatac tcttgttggt ggtgttgcag gacttcttcg tagctacgga gttgctgttc
    11941 ataaaggaat tggtacaatc actaaagaca agaacgtctt ggtaaatggt tctgaattgc
    12001 ttgaaaccaa gaaaatcatt cttgctggtg gttcaaaagt cagcaagatc aacgtccctg
    12061 gtatggaatc tccacttgtc atgactagtg atgacattct tgaaatgaac gaagtgccag
    12121 aaagccttgt tatcatcggt ggtggagttg tcggtatcga actcggtcag gccttcatga
    12181 catttggttc aaaagtgact gttatcgaaa tgatggaccg tatagttcca gctatggatg
    12241 tggaagtttc taagaacctt cgcttgatcc ttgagcgtaa aggaatgacc atcttgactg
    12301 gtactaaact gcaagaaatc attgaggaaa atggtcaact tcgtatcaag gttgaaggaa
    12361 aagacgatat catcgcaagc aaagctcttc tttcaattgg tcgtatgcca gaccttgaag
    12421 gtattggaga ggttgagttt gaattggatc gtggttgtat caaggtcaac gaatacatgg
    12481 aaacttcagt tccaggcatt tatgcaccag gtgacatcaa cggtactaag atgttggctc
    12541 acgcagcttt ccgcatgggt gaagtttccg ctgaaaatgc ccttaaagga aatcatgcag
    12601 ttgccaaatt gaatttgact cctgcagcca tctacactct tcctgaagta gcagcagtag
    12661 gtttgacaga agaacaagcc cgtgagaaat acgatgttgc catcggtaag tttaactttg
    12721 ctgctaacgg tcgtgctatt gcatctgacg cagctcaagg tttcgtaaaa gttatcgctg
    12781 ataagaaata cggagaaatc cttggtgtac acattattgg tcctgcagcc gcagaattaa
    12841 taaacgaagc atcaagcatc atcgaaatgg aaatcactgt tgaggaaatg ctgaagacca
    12901 tccacgggca cccaacttac tctgaagtga tgtacgaagc gtttgcagat gttctaggaa
    12961 tggccatcca ttcacctaag aaaaaataaa acgaagatag attagactgg aaggttattt
    13021 ccagtttcta tcatataaag taaagggata tcatgaaata cattatcaat cattcaaatg
    13081 acactgcttt taatattgcc ttggaagaat acgcctttaa acaccttttg gatgaggatc
    13141 aaatcttcct actttggatt aacaagccat ctatcattgt tggtcgtcac cagaacacta
    13201 tcgaagaaat caaccgtgat tatgttcgcg aaaatggtat tgaggtagtt cgccgtatta
    13261 gtggtggtgg agctgtttac cacgatttaa ataacctcaa ctacacgatc atctccaaag
    13321 aagatgaaaa taaggcattt gacttcaaga gcttctcaac tccggttatc aataccctgg
    13381 ctcaactcgg ggttaaagct gagttcacag gtcgtaatga ccttgagatt gatggtaaga
    13441 agttctgtgg caatgcccaa gcctatatca acggccgtat catgcaccac ggttgcttgc
    13501 tctttgacgt tgatttgtca gtcctcgcaa atgcccttaa ggtttcaaaa gataaatttg
    13561 aatcaaaagg tgtgaaatcc gtccgtgccc gtgtaaccaa tattatcaat gaattaccaa
    13621 aaaaaatcac agtcgaaaaa ttccgtgatt tactcttgga atacatgaaa aaagagtacc
    13681 cagagatgac tgaatacgtc ttttcagaag aagaattggc cgaaataaat cgcatcaagg
    13741 atactaagtt tggaacttgg gactggaact atggtaaatc acctgaattt aacgtccgtc
    13801 gtggaaccaa attcactagt ggtaaggttg aagtctttgc taacgttact gaatcaaaaa
    13861 tccaagacat caagatttat ggtgacttct ttggtattga agacgttgct gcagtagaag
    13921 ctgtccttcg tggggtgaaa tacgaacgcg aagatgttct taaggcgcta aaaaccattg
    13981 atatcacacg ctacttcgct ggtattagcc gtgaagaaat cgctgaagcg gtagttggat
    14041 aaatcaaaaa gaagttggcc aacttctttt tttgatattt atttacataa tttaaaatac
    14101 gtaaaatcat aaactatcca gagcattctt ttgttcatca ctaacaatat gggtatagag
    14161 gtcagtgact tgtgtgctgg catgtcctag ttggtgactg actaaaactt gtgatttagt
    14221 cgcatcatag agcctagttg ctagcgtatg gcgcagttta tggggtgtta cacgcacttt
    14281 aaaatcctct gagtatttag caaccatttt ctcaacgcta gaagcatcga tacgattagg
    14341 aacacctctg tagagagtta aaaaaagggc tgtatctgtt ttttccgttt tatagcgttg
    14401 attccgaatg gccagataat tctctaaata aggtttagca aaagcagcga cattgactga
    14461 gtcacgtttg ccaccttttc gagtaacatc aataaccatc atttttagat tgagatctct
    14521 tagatctaga ttaacagctt cagataagcg aacaccagat gccaagagaa gggcaataat
    14581 ggctaaatca cgttctttat ttttgttgaa tgatgagaga gctcgatttg aaagctgttg
    14641 tgggtgctct tgatcgatat aagttagaaa accttctgtt tcatcaccta gaaagagttt
    14701 ttgcttgata ttttcagctc tggcagcaag ggtttctttc tttttcttgg ttgaaacttt
    14761 tttcattaca ttacgataga aataaggttc cccctgatcg ttttcaacct cctcggttag
    14821 atacttgtaa agactagaaa gtgctgataa ggttcgattg atagttgtct gtgaaacacc
    14881 ttgttttgtt gtattagcat tcagcaaggg acgttcacgt agataaagga taaaggattc
    14941 catgtctttc ttagacatat tttccaaaac tgataaagga atatcggata ttttatcagc
    15001 gtttgaaata ccagactcca aaacccagct gaaaaatcgg tcatattcct taaggtattc
    15061 gtacagggtt gtaaaactgt agggtacagc cagcttagat tggtagtatt ccagaacata
    15121 ccagggcatg agttgtttta gtttgtcgat tcgttccagt aaaatctcac gtttcatgta
    15181 ttttctccat aagtaagtat actagtagta tagcatagac ttgtatattt ttcaagaaaa
    15241 ttatagtttt tctgaaagat gttataggag tttttcaaag tgataaaaag acttagacct
    15301 acaaacaaaa cagaataagg aaaataataa aaatctcacc cactaaactt ctgttaatac
    15361 tacataactg aagagctata taaggagcta tgagatacaa aacacattgt ataatagatt
    15421 gaaactagaa tagtacatct ggacttctta aacattgcta gaaattgatt tgattgtcct
    15481 gattgtttta tcctatttct atttcatttc tctatataat tgctattgtt ttctttttca
    15541 tgattttaat cttactgtac agatttgata cagtaaactc ctttctagct ttatacttta
    15601 tcatttctaa cttaattata gtcttatttt taataaagtt caattattta tatgtaaaaa
    15661 tcctcatcag taaaaa
//
LOCUS       DAVHTH010000047        14441 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.047, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000047 DAVHTH010000000
VERSION     DAVHTH010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14441)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14441)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14441
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.047"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            complement(5..1855)
                     /locus_tag="VVR63_001564"
     CDS             complement(5..1855)
                     /locus_tag="VVR63_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEU6129568.1"
                     /translation="MNKKLTDYVIDLVEILNKQQKQVFWGIFDIFSMVVSIIVSYILF
                     YGLINPAPVDYIIYTSLAFLFYQLMIGFWGLNASISRYSKITDFMKIFFGVTASSVLS
                     YSICYAFLPLFSIRFIILFILLSTFLILLPRITWQLIYSRRKKGSGDGEHRRTFLIGA
                     GDGGALFMDSYQHPTSELELVGILDKDSKKKGQKLGGIPVLGSYDNLPELAKRHQIER
                     VIVAIPSLDPSEYERILQMCNKLGVKCYKMPKVETVVQGLHQAGTGFQKIDITDLLGR
                     QEIRLDESRLGAELTGKTILVTGAGGSIGSEICRQVSRFNPERIVLLGHGENSIYLVY
                     HELIRKFQGIDYVPVIADIQDYNRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFK
                     NNIRGTYNVAKAVDEAKVSKMVMISTDKAVNPPNVMGATKRVAELIVTGFNQRSQSTY
                     CAVRFGNVLGSRGSVIPVFERQIAEGGPVTVTDFRMTRYFMTIPEASRLVIHAGAYAK
                     DGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIVEVGIRPGEKLYEELLVSTELVD
                     NQVMDKIFVGKVNVMPLESINQKIGEFRTLSGDELKQAIIAFANQTTHIE"
     gene            complement(1897..3054)
                     /locus_tag="VVR63_001565"
     CDS             complement(1897..3054)
                     /locus_tag="VVR63_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU6129569.1"
                     /translation="MSSKVSGFQDKNGKVLKIMIEWWKEKFRRVVVTQNVESLLVSIV
                     ISAYNEEKYLPGLIEDLKNQTYPKENIEILFINAMSTDGTTAIIQQFIKEDTEFNSIR
                     LYNNPKKNQASGFNLGVKHSVGDLILKIDAHSKVTESFVMNNVAIIQQGEFVCGGPRP
                     TIVEGKGKWAETLHLVEENMFGSSIANYRNSSEDRYVSSIFHGMYKREVFQKVGLVNE
                     QLGRTEDNDIHYRIREYGYKIRYSPSILSYQYIRPTFKKMLHQKYSNGLWIGLTSHVQ
                     FKCLSLFHYVPCLFVLSLVFSLALLPITFVFITLLLGAYFLLLSLLTLLTLLKHKNGF
                     LIVMPFLLFSIHFAYGLGTIVGLIRGFKWKKEYKRTIIYLDKISQINQNML"
     gene            3112..4278
                     /locus_tag="VVR63_001566"
     CDS             3112..4278
                     /locus_tag="VVR63_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CynX/NimT family MFS transporter"
                     /protein_id="HEU6129570.1"
                     /translation="MKKQSLFFVPGIILIGVSLRTPFTVLPIILGNISQGLEVEVSSL
                     GVLTSLPLLMFTLFSPFSTRLAQKIGLEHLFTYSLFFLTIGSLIRLINLPLLYLGTLM
                     VGASVAVINVLLPSLIQANQPKKIGFLTTLYVTSMGIATALASYLAVPITQASSWKGL
                     ILLLTLLCLATFLVWLPNHRYNHRLAPQTKQKSQIKVMRNKQVWAIIIFSGFQSLIFY
                     TVMTWLPTMSIHAGLSSHEAGLLTSILSLISIPFSMTIPSLTTSLSTRNRQLMLTLVS
                     LAGVVGISMLFFPINNFIYWLAIHLLIGTATSALFPYLMVNFSLKTSAPEKTAQLSGL
                     SQTGGYILAAFGPTLFGYSFDLFHSWVPSVAALLLIDILMTVALFTVDRADKIL"
     gene            4417..4743
                     /locus_tag="VVR63_001567"
     CDS             4417..4743
                     /locus_tag="VVR63_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEU6129571.1"
                     /translation="MYFPTSSALIEFLILAVLEQGDSYGYEISQTIKLIANIKESTLY
                     PILKKLEGNSFLTTYSREFQGRMRKYYSLTNGGIEQLLTLKDEWALYTDTINGIIEGS
                     IRHDKN"
     gene            4730..5323
                     /locus_tag="VVR63_001568"
     CDS             4730..5323
                     /locus_tag="VVR63_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HEU6129572.1"
                     /translation="MTRTEYLTQLELYLKKLPEADRIEAMDYFRELFDDAGVEGEEEL
                     IASLGTPKEAAHEVLSNLLDKKINEAPAQKNNRQILHIALLALLAAPIGIPLGIAILV
                     TLFAILVAALTVILAFFAVSILGIIGGFLFLVESFTILAQAKSAFILIFGSGLLAIGA
                     SSLVLLGISYVARFFGLLIVRLVQFVLKKGKRGNQHA"
     gene            5316..6227
                     /locus_tag="VVR63_001569"
     CDS             5316..6227
                     /locus_tag="VVR63_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 domain-containing protein"
                     /protein_id="HEU6129573.1"
                     /translation="MRKWTKGFLIFGVVTTVIGFILLFVGIQSDGIKSLLSMSKEPVY
                     DSRTEKLTFGKEVENLEITLHQHTLTITDSFDDQIHISYHPSLSAHHDLITNQNDRTL
                     SLTDKKLSETPFLSSGIGGILHIASSYSSRFEEVILRLPKGRTLKGINISANCGQTTI
                     INASLENATLNTNSYILRIEGSRIKNSKLTTPNIVNIFDTVLTDSQLESTENHFHAEN
                     IQVHGKVELTAKDYLRIILDQKESQRINWDISSNYGSIFQFTREKPESRGTELSNPYK
                     TEKTDVKDQLIARSDDNIDLISTPSRR"
     gene            6289..7353
                     /locus_tag="VVR63_001570"
     CDS             6289..7353
                     /locus_tag="VVR63_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6129574.1"
                     /translation="MKQEWFESNDFVKTTSKNKPEEQAQEVADKAEETIADFDTPIGK
                     NTQVEEEVSQAEVELESQQEKKIETPEVCEARTEIEEKKASNSTEEESDLSKETEKVT
                     IAEESQEALPQQKATTKEPLLISKSLESPYIPDQAPKSRDKWKEQVLDFWSWLVEAIK
                     SPTSKFETSITHSYTAFLLLILFSASSFFFSIYHIKHAYYGHIASINSRFPEQLAPLT
                     LFSIISILVATTLFFFSFLLGSFVVRRFIHQEKDWTLDKVLQQYSQLLAIPIFLTSIA
                     SFFAFFDSLRFTALLCVISIGIILLASLHIITRPSQASETDSFYQLFLSVLVNGVIIL
                     LFFVAEVALIGDYLRILAFL"
     gene            complement(7425..8285)
                     /locus_tag="VVR63_001571"
     CDS             complement(7425..8285)
                     /locus_tag="VVR63_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4299 domain-containing protein"
                     /protein_id="HEU6129575.1"
                     /translation="MAKTFFIPNKQSILGEQEILNAKSILALLDGLESHSYDVVYLRQ
                     PLNRLEYIECAIVGQSQFLFKVSYADGQKAYRVDLPDLLTKTDWQIIKSFLDALLAYT
                     ETDIEGLDGFDFEAYFQASIQAYLADPVARFTICQGIFNPIFFSRENLKSFLEADGLA
                     QFEARVRAVQETDAYFARVSFYQDGEGKVHGVYHLAQGVKTVLPREPFVPAAYIEQLV
                     DKEVQWEIDLVQITGDGSKPEDYESIARLDYAKFLEVLPPSFYHQLDANQLEIQPILG
                     QDFKTLAQEK"
     gene            complement(8559..9545)
                     /locus_tag="VVR63_001572"
     CDS             complement(8559..9545)
                     /locus_tag="VVR63_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HEU6129576.1"
                     /translation="MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADE
                     GINGTVSGDYETTQKYMDYVHSLPGMEELWFKIDEENEQAFKKMFVRYKKEIVHLGLE
                     DNDFDNDINPLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKD
                     PEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILT
                     SEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV"
     gene            complement(9817..11292)
                     /locus_tag="VVR63_001573"
     CDS             complement(9817..11292)
                     /locus_tag="VVR63_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3502 domain-containing protein"
                     /protein_id="HEU6129577.1"
                     /translation="MKNWKKYAFASASVVALAAGLAACGNLTGNSKKAADSGDKPVIK
                     MYQIGDKPDNLDELLANANKIIEEKVGAKLDIQYLGWGDYGKKMSVITSSGENYDIAF
                     ADNYIVNAQKGAYADLTELYKKEGKDLYKALDPAYIKGNTVNGKIYAVPVAANVASSQ
                     NFAFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDVVPFAIGKVFIPSDNFDYPV
                     ANGLPFVIDLEGDTTKVVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTSFDLQQD
                     TWFVREETVGPADYGNSLLSRVANKDIQIKPITNFIKKNQTTQVANFVISNNSKNKEK
                     SMEILNLLNTNPELLNGLVYGPEGKNWEKIEGKENRVRVLDGYKGNTHMGGWNTGNNW
                     ILYINENVTDQQIENSKKELAEAKESPALGFIFNTDNVKSEISAIANTMQQFDTAINT
                     GTVDPDKAIPELMEKLKSEGAYEKVLNEMQKQYDEFLKNKK"
     gene            complement(11502..12425)
                     /locus_tag="VVR63_001574"
     CDS             complement(11502..12425)
                     /locus_tag="VVR63_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001075101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU6129578.1"
                     /translation="MAKKKIKKEKIDNVGIHSFSKKADIFFSIISGLIALSCILPFVF
                     VIIISVTDEKSLLQYGYSFFPSQFGLDGFEFLAQFKDKILQALFISVFVTVVGTLTNV
                     FITTTYAYAISRTTFKYRRFFTIFVLLSMLFNAGLVPGYIMVTRVLQLGDTVWALIVP
                     MLLSPFNIILMRSFFKKTIPEAILESARIDGASEARIFFQICLPLSLPGIATITLLTA
                     LGFWNDWFNALLYIKSDNLYPLQYLLMQIQQNMDYIAKAVGLTGQLGVALPKETGRMA
                     MVVVATLPIAILYPFFQRYFVKGLTIGGVKE"
     gene            complement(12439..13368)
                     /locus_tag="VVR63_001575"
     CDS             complement(12439..13368)
                     /locus_tag="VVR63_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU6129579.1"
                     /translation="MKKFSKTLRDNWIFLLMVLPGALWLILFFYIPVFGNVVAFKDYH
                     MTSNGFIDSIINSKWVGLDNFRFLFSSRDAFIITRNTVLYNLGFIFLGLVVSVGIAII
                     LSELRSKRMVKIFQTSMLFPYFLSWVIISFFTDAFLNIDKGVFNHLLESLGLKEVNFY
                     ADLGIWPYLLLFLGIWKGFGYSSVMYYATIMGIDPTYYEAATVDGASKWQRIRNVTIP
                     QLTPLVTVLTILAVGNIFRADFGLFYQIPHNAGQLYNVTNVLDVYVFNGLTQTADIGM
                     AAAAGLYQSVVGLILVILSNLLARRVDPNSALF"
     gene            complement(13687..13908)
                     /locus_tag="VVR63_001576"
     CDS             complement(13687..13908)
                     /locus_tag="VVR63_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6129580.1"
                     /translation="MSLQIKLKKLAKELSKLLKDSNLETVDKDVLENSQKELQKAVLF
                     LADEKGSEHTEAEVIDNLKEVIAKLKANA"
     gene            complement(13862..14122)
                     /locus_tag="VVR63_001577"
     CDS             complement(13862..14122)
                     /locus_tag="VVR63_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6129581.1"
                     /translation="MTGVSNPTTDSARLVLAEAKKAFADDSLTEQGLRDILQTVKDAI
                     ASLESIKESQSATKDGGQTAGKETAGEDESANQTQEISQGIK"
     gene            14202..14339
                     /locus_tag="VVR63_001578"
                     /pseudo
     CDS             14202..14339
                     /locus_tag="VVR63_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT         4316 a         3101 c         2655 g         4369 t
ORIGIN      
        1 ttttttattc aatgtgggtt gtttgattag caaaggcgat aatagcttgc ttcaactcat
       61 ctccactgag agtgcggaac tctccaatct tttgattgat ggattctaaa ggcatgacat
      121 taaccttacc aacgaaaatc ttatccataa cttgattatc aacgagttcg gttgatacca
      181 agagttcttc gtagagtttt tcacctgggc ggattccaac ttcaacgatt ggaatttcac
      241 tttcagtgtg gccacttaga agcaccatct tcttggccaa gtcataaatc ttgactggtt
      301 tgcccatatc aaggataaag acttccccat ctttggcata agcaccagca tggataacca
      361 gacggctagc ttctggaatg gtcataaagt aacgggtcat gcggaagtct gtcaccgtta
      421 caggcccacc ttcagcaatc tgacgttcaa agactggaat gacactacca cggctaccaa
      481 gaacattccc aaaacgaact gcacagtagg ttgattggct acgttggtta aagccagtga
      541 caatcaactc cgccacgcgc ttggttgctc ccataacatt tggtggattg actgccttat
      601 ctgtcgaaat cataaccatc ttagacactt tagcttcatc aacagcctta gcaacattgt
      661 aagttccacg gatattgttt ttgaaggctt cttttggatt gcgctccatc ataggaacat
      721 gcttgtgggc tgccgcatga taaacaatag caggtttgta ctgctcaaag acttgcaaca
      781 aacgattata gtcttgaatg tccgcaatca caggtacata atcaatccct tggaacttac
      841 gaatcaattc atgataaaca aggtagattg agttttcccc atgaccgagc aagacaatac
      901 gttcaggatt gaagcgacta acttgacgac agatttcaga accgattgaa cctccagctc
      961 ctgtgactaa gatggtctta cctgtcagtt cggcacccag acgcgattcg tcaagacgga
     1021 tttcctgacg acccaaaagg tccgtaatat caattttttg gaagccagta cctgcttggt
     1081 gaaggccctg aacaacagtt tcaaccttag gcatcttgta acatttgaca cccagcttat
     1141 tacacatctg caagatacgc tcatattctg acggatccag cgacggaatc gcaacgatga
     1201 cacgctcgat ttgatggcgt ttggctaatt caggcagatt gtcataagag cccaaaacag
     1261 gaataccacc aagtttttga ccctttttct tagaatcctt atccaaaata ccgaccagtt
     1321 ctaattcact ggttggatgt tggtaactat ccataaagag agccccacca tcaccggcac
     1381 caatcaagaa ggtccgacgg tgttctccat caccactacc ttttttgcgt ctggagtaga
     1441 ttaactgcca agtaatccgt ggcaataaaa tcaagaaggt actcaacaag ataaagagaa
     1501 tgatgaaacg gatggagaag agtggcaaga aggcataaca gatactatat gacaagacac
     1561 tgctagcagt cacaccaaaa aagattttca tgaaatccgt aatcttgctg taacgactaa
     1621 tgctcgcgtt caacccccaa aaaccaatca tcaattgata gaacaagaag gccaaactcg
     1681 tatagataat gtagtcaaca ggtgctggat taatcagccc ataaaataaa atataagata
     1741 caattatgga aaccaccata ctgaaaatat caaatattcc ccagaaaacc tgcttttgtt
     1801 gtttatttaa aatttccacc agatcaatca cataatctgt tagtttttta ttcatagaaa
     1861 tctactcctc cttaaaagag ttttactata ttgttattat agcatatttt gatttatttg
     1921 gcttatttta tccaaataaa ttattgttct cttgtactcc ttcttccatt taaatcctct
     1981 aattaaacct acaatcgtcc caaggccata agcaaagtga atggaaaata aaagaaaggg
     2041 catcacaatt agaaatccat ttttatgttt taataaagtc agcaaagtga gtaatgacaa
     2101 aagtagaaaa taggcaccta atagtaaagt tatgaatacg aatgtgatcg gtaacaatgc
     2161 tagactaaac acaagactca aaacaaataa acaaggaaca tagtgaaata atgataaaca
     2221 cttaaactga acatgacttg tcaagccaat ccacaaacca tttgaatact tttgatgcag
     2281 cattttcttg aatgttggtc gaatatactg ataagataga atacttgggc tatagcggat
     2341 tttataacca tattctcgaa ttctataatg aatatcatta tcttcagttc ggccaagttg
     2401 ctcatttact aaaccaacct tctggaaaac ctctcgttta tacattccat gaaaaataga
     2461 agaaacatat ctatcctcag aactatttcg ataattggca atgctactgc caaacatatt
     2521 ttcctcaaca agatgcaagg tctctgccca ttttcctttt ccttcgacaa tcgtcggtct
     2581 aggcccccca cagacaaatt caccttgttg aataatagcc acattgttca ttacaaaact
     2641 ctcagtaact tttgaatgag catcaatttt taaaataagg tcccctacag aatgtttaac
     2701 tcccaggtta aaaccactag cttgattttt cttaggattg ttatacaatc taattgagtt
     2761 aaactctgta tcttccttta taaattgctg aatgatagct gtggtcccat ctgtggacat
     2821 agcatttata aatagaattt caatattctc tttaggatag gtttgatttt ttaagtcttc
     2881 aattagacca ggcagatatt tttcttcatt gtatgcactg attacaatgg atacgagaag
     2941 actttcaaca ttttgagtca ctactactct cctgaatttt tccttccacc attctatcat
     3001 aattttcaag actttcccat ttttatcttg aaagccagaa accttacttg acattatagt
     3061 gaaaaagcct taaaataagc tgttattaaa atcagctaga agaggtatta tatgaaaaag
     3121 caatcactct tttttgttcc aggtattatc ctgattggtg tttccttgcg aactcctttt
     3181 actgttttac ccattatttt gggaaatatt tcgcaaggtc tggaggtaga agttagttcg
     3241 cttggtgtct tgaccagcct gcctctcctt atgtttaccc tcttttcacc attttctacc
     3301 cgactggctc agaaaatcgg cttggagcat ctcttcacct acagcctctt cttcttgacc
     3361 atcggctcac ttattcgact aatcaatctg cccctgctct atctaggaac cttgatggtt
     3421 ggggcaagtg tcgcagtcat caatgtcctg cttcctagtc ttatccaagc caatcaacca
     3481 aagaaaattg gttttctgac caccttatat gtaacgtcta tggggattgc aacggctctg
     3541 gcttcctatc tagctgtgcc cattacacaa gccagttctt ggaaaggact tatccttctc
     3601 ctcacgttac tctgtctagc aacttttttg gtctggctcc caaatcaccg ctataatcat
     3661 agactagctc cacaaaccaa acaaaaaagt caaataaagg tcatgcgtaa taaacaggtt
     3721 tgggcaatta ttatcttttc aggttttcaa tccttgatct tttacaccgt catgacctgg
     3781 ttacctacca tgtctatcca tgcaggtcta tccagtcacg aagctggctt gctgacttct
     3841 atcttatctc tgattagcat tcctttttca atgaccatcc caagcctgac aaccagttta
     3901 tctactcgca accgtcagct catgctcact ctggtttcac tagctggtgt ggtcggcatt
     3961 tccatgctct ttttcccaat caataatttc atttactggc ttgccatcca tctcctcatc
     4021 ggaaccgcaa ccagcgccct cttcccttat ctcatggtca acttttcact caagacaagc
     4081 gcccctgaaa agacagccca attgtccggc ctatctcaaa caggaggcta tatcctagca
     4141 gcctttgggc caaccctctt tggttacagt tttgacctgt tccactcttg ggtaccatct
     4201 gtagctgccc tcttgctcat cgatatcctg atgactgtgg ccctctttac agtggacaga
     4261 gcggataaga tcctttaaac ttctagtttt agctagaagt tttttatata taaaaatttt
     4321 acacatttct cttgacaggg ctttctttta gatgtacaat gtatgtgtag aaaaattata
     4381 tataaaaatc ttacacatta gaaaaggagg tttcccatgt actttccaac atcctctgcc
     4441 ttgattgaat ttctcatctt ggccgtactg gagcagggtg attcttatgg ttatgagatt
     4501 agccaaacca ttaagctaat cgctaatatc aaagaatcca cactctatcc cattctcaaa
     4561 aaattggaag gcaatagctt tctgacaacc tattctagag agttccaagg tcgcatgcgc
     4621 aaatactact ccttgacaaa cggtggtata gagcagctct tgaccctaaa agatgaatgg
     4681 gcactctata cagacaccat caatggcatc atagaaggga gtatccgcca tgacaagaac
     4741 tgaatacctg actcagctag aactctatct caagaaacta cctgaagctg accgtatcga
     4801 agccatggac tatttcagag agctctttga cgatgctgga gtcgaaggag aagaagaact
     4861 catcgctagt ttgggaactc ccaaagaagc ggcccacgaa gttctatcca atcttctcga
     4921 taaaaaaatc aatgaagcac ccgctcaaaa aaataaccga caaattttac atatcgcctt
     4981 gttagccctc cttgcagcac ctatcggcat tcctctggga atcgccatcc tcgtgaccct
     5041 gttcgcaatc cttgtagccg ctttgactgt cattctggct ttctttgcag tttccatact
     5101 gggtatcatc ggcggattcc tatttttagt tgaaagtttc actatcctcg cccaagccaa
     5161 atcagccttt atcttgattt ttggttctgg tttactggct atcggtgctt cttcgctagt
     5221 tttacttggc atttcctatg tagctcgctt cttcggtcta ctcattgttc gtctggtaca
     5281 atttgttctt aaaaaaggaa agagaggtaa tcagcatgcg taaatggaca aaaggatttc
     5341 tcatctttgg tgtggtgact accgttatcg gctttatcct gctttttgta ggtatccaat
     5401 ctgacgggat taagagccta ctttccatgt ccaaagaacc tgtctatgat agccgtacgg
     5461 aaaagctaac ctttggcaag gaagtcgaaa acctagaaat tactctccac caacacacgc
     5521 tcaccatcac agactctttc gatgatcaaa tccacatttc ttaccatcca tctctttctg
     5581 ctcaccatga tcttatcacc aatcagaacg atagaactct gagtctcact gataagaaac
     5641 tgtctgaaac tccgtttctc tcttctggaa ttggtgggat tcttcatatc gcaagtagct
     5701 actctagtcg ttttgaagaa gttattctcc gactaccaaa agggagaact ctaaaaggga
     5761 tcaacatctc agccaattgc ggacaaacca ccatcataaa tgctagcctt gaaaatgcaa
     5821 ccctcaatac aaacagctat atcctccgaa ttgaaggaag tcgtatcaaa aacagtaaac
     5881 tcacaacgcc caatatcgtt aatatctttg atacagttct tacagatagt cagctagagt
     5941 caacagagaa tcacttccac gctgaaaata tccaagtcca tggcaaggtt gaactgactg
     6001 ccaaagatta tctcagaatc atcctagacc agaaagaaag ccaacgaatt aactgggaca
     6061 tctcaagcaa ctatggttct atcttccaat tcacaagaga aaagcctgaa tcaagaggta
     6121 cggaattaag caacccttac aaaactgaaa aaaccgatgt caaggatcaa ctcattgcga
     6181 gatctgatga taatattgat ctaatatcca caccaagcag acgttgacaa aaacgcttac
     6241 atctgctact atggaagcat atttatctaa ccaaaaggag gttctaccat gaaacaagaa
     6301 tggtttgaaa gtaatgattt tgtaaaaaca acaagcaaga acaagcctga agagcaagct
     6361 caagaggttg cagacaaggc tgaagaaacg atagccgatt tcgatacacc aattggaaaa
     6421 aatactcaag tagaggagga agtctctcaa gctgaagtcg aactggaaag ccagcaagaa
     6481 aagaaaattg aaactcctga agtctgtgaa gcgagaacag aaatagaaga aaagaaggca
     6541 tctaattcta ctgaagaaga gtcagacctt tctaaagaaa cagaaaaagt cactatagct
     6601 gaagagagcc aagaagctct tcctcagcaa aaagcaacca cgaaagagcc acttcttatc
     6661 agtaaatctt tagaaagtcc ttatatcccc gaccaagctc caaaatctag ggataaatgg
     6721 aaagagcaag tgcttgattt ttggtcttgg ctagtggaag cgatcaaatc tcctacaagt
     6781 aagtttgaaa caagtatcac acacagttac acagcctttc tcttgctcat tctgttttct
     6841 gcatcttcct ttttctttag tatctatcac atcaaacatg cttactatgg acatatagca
     6901 agcattaaca gtcgcttccc tgagcagcta gctcctttaa ctcttttttc tatcatctct
     6961 atcctagtag cgacaacact cttcttcttt tcattcctct tgggtagttt cgttgtgaga
     7021 cgatttatcc accaggaaaa ggactggacg ctagacaagg ttctccaaca atatagtcaa
     7081 ctcttggcaa ttccaatctt cctcacttct attgctagtt tctttgcttt ctttgatagc
     7141 ctacgattta cagccctctt gtgtgtaatt agcattggaa tcattctgct tgccagtctc
     7201 catatcatta caagaccaag tcaagcaagt gaaaccgact ccttctatca attattcttg
     7261 tctgtccttg tgaacggagt tattatcctc ctcttctttg tagctgaagt ggcactgatt
     7321 ggagattatc ttcgtatctt ggcctttctt taaaattcaa tcctgtcatc cttggcagga
     7381 ttttttctat gtcaaaaaag caagtcgatt gacctgcttc tgctttactt ttcttgtgct
     7441 aatgttttaa aatcttgtcc taggatgggt tgtatttcta attgattggc gtctagctgg
     7501 tggtaaaaag atgggggtaa cacctctaag aattttgcat agtccaagcg agctatggat
     7561 tcatagtctt ctggtttaga gccgtctcct gtgatttgaa ccaagtcaat ctcccactgg
     7621 acttccttat ccaccaattg ctcaatatag gctgcaggaa caaacggttc tctcggtaaa
     7681 actgtcttga ctccttgagc tagatggtaa acgccatgca cttttccttc tccatcctga
     7741 tagaaggaaa ctctcgcaaa gtaggcatct gtctcttgaa ccgcacgcac acgcgcttca
     7801 aactgagcca agccatctgc ctctaaaaag cttttcaagt tctcacgact aaagaaaata
     7861 ggattaaaaa ttccttggca aatcgtaaaa cgagctacag ggtctgctag ataggcttga
     7921 atacttgctt ggaaataagc ttcaaaatca aaaccatcta gcccttcaat atcagtctct
     7981 gtataagcaa gcaaagcatc taaaaatgac ttgataatct gccagtctgt ctttgttagt
     8041 aggtcaggaa gatcgacacg gtaagccttt tgaccatcag cataactgac cttaaaaaga
     8101 aattgtgatt gccccactat cgcacactca atatactcga gacgattaag aggctgacgg
     8161 agatagacta catcatagct atgtgactcc aaaccgtcta gcaaggccaa gatcgacttg
     8221 gcattcaaaa tctcttgttc tcctaaaatg ctctgtttat ttggaataaa aaatgttttc
     8281 gccataactg gactcctttg aaatcgttta catcagtgta ccttattttt ctgaaagata
     8341 caaaaacaaa ctttatattc ttcgaaaatc tcttcaaacc gcgtcagctt cgccttgccg
     8401 tagatatatg taactgactt cgtcagtctt atctacaacc tcaaagcagt gctttgagca
     8461 gcctgcagct agcttcctag tttgctcttt gattttcatt gagtattaga tttttgagta
     8521 caaagcatag aaaaacagcc cctaaggact gtttgatctt atacagtagc tgcctgatcc
     8581 aagctttcac cgatagcggc taggcgctca atcacttcag cttgtgtcaa ttcatttttt
     8641 gaaacatagc ggttacgtgg gtgaacacgg cactcgtgtg agcatccacg aaggtacttg
     8701 tcttcatttt cttctgatgt caagatacga cggttacaga agggatttcc acagttgaca
     8761 taacgttcac atggtgttcc atcaaaccag tctttcccta cgatggttgg gttgacatgg
     8821 ttgacatcaa cggcgatacg ctcgtcaaat acgtacattt ttccatccca aagctcacct
     8881 tgaacttctg ggtctttacc gtaagttgcg attcctccgt gcaattggcc aacatctttg
     8941 tagccttcac ggaccatcca gcctgagaat ttctcacagc gaacgccacc tgtacagtaa
     9001 accacgacac gcttgtccat gaatttttcc ttgttatcac ggacccattg tggtaactca
     9061 cggaagttgc gaatatctgg gcgaatagct ccacggaaat gtcctaggtc gtactcataa
     9121 tcgttacgtg tgtcaaggac aacggtatct ttatcaagaa gcgcttcttt gaactctttt
     9181 ggagacaagt aagcacctgt tgtttcaagt gggttgatgt cattgtcaaa gtcgttgtct
     9241 tccaaaccaa ggtggacaat ttctttcttg tagcgaacaa acatcttctt gaaggcttgt
     9301 tcattttctt cgtcaatctt gaaccagagt tcttccattc ctggaaggct gtgaacgtag
     9361 tccatgtatt tttgagttgt ttcatagtca cctgaaactg ttccgttaat tccctcgtca
     9421 gcgactagga tacggccttt aaggccgatt gatttacaga aagccaagtg gtctgcagca
     9481 aattgctctg cattttcaat tggagtataa aggtagtaaa gtaagacacg aatatctttt
     9541 gccataagat ttgttctctt ttctattctt aaattttcta aattttttat ttatctacac
     9601 tagtatacct gcttgagaaa acgaatgcaa tttatttgac tggaaattgt agagggttct
     9661 cgaaatttcc tgaatggtta aaataaggac aagagaaaac atggatatct atatccttgt
     9721 gccaaaaaaa ccactgccct ccccagacca acctgaggaa agcagtgatt cttattttag
     9781 gagttaggaa tgaatacacg aaatcaattt agctgattat tttttgtttt tcaagaattc
     9841 atcgtattgt ttttgcattt cgttcaatac tttttcgtag gcaccttcag atttcaattt
     9901 ttccatcaat tctggaatcg ctttatctgg gtctacagta ccagtgttga tagctgtatc
     9961 aaattgttgc attgtgttag caatagctga gatttcagat ttcacattgt cagtattgaa
    10021 gataaatcca agcgctggag attctttagc ttctgccaat tctttcttag aattttcgat
    10081 ttgttggtct gtaacgtttt cgttgatgta aaggatccag ttgttaccag tgttccatcc
    10141 acccatgtga gtgtttcctt tgtagccatc aagaacgcga acacggtttt ctttaccttc
    10201 aattttttcc cagttcttgc cttctggacc gtaaacaaga ccgttcaaga gttctggatt
    10261 cgtattcaag aggttcaaga tttccattga tttttctttg ttcttagagt tgtttgagat
    10321 gacaaagtta gcaacttgtg ttgtttggtt tttcttgatg aagttagtaa ttggtttgat
    10381 ttggatatct ttgttggcaa cacgtgaaag caagctgtta ccgtagtcag ctggtcctac
    10441 tgtttcttca cgaacgaacc aagtatcttg ttgaaggtca aaggaagtat cgcttgttgc
    10501 gacgtctttt ggaatgtagc cagcttcata gaatttgtga agagtcttca agtgttcttt
    10561 gaaacgaggc acttcgtaac ggtttacaac tttagtagta tcgccttcaa ggtcgataac
    10621 gaatggaaga ccgtttgcta ctgggtagtc aaagttatca gatgggatga aaactttacc
    10681 aatagcaaat ggtactacgt ctggagcttt ttctttgatt tgtttcaaga ctggctcaag
    10741 agtttcgtaa gaagtaacac ctgaaatatc gataccatat ttagcaagga gagttccgtt
    10801 gaaggcaaag ttttgagatg atgcaacgtt ggctgcaact ggaacagcgt aaatcttacc
    10861 atttacagta ttacccttga tgtaagctgg gtcaagtgct ttgtaaaggt ctttaccttc
    10921 ttttttgtac aattctgtca agtcagcgta agcacctttt tgagcattta caatatagtt
    10981 atctgcaaag gcaatatcat agttttcacc agatgatgtg ataactgaca ttttcttacc
    11041 atagtcaccc cagccaaggt attggatatc caatttggca ccaacttttt cttcgatgat
    11101 tttgttggca tttgctaaca attcatccaa gttatctggt ttgtcaccga tttggtacat
    11161 ttttataaca ggtttgtcac ctgaatcagc agcttttttg ctgttacctg tcaaatttcc
    11221 acaagcagca agacctgcag ccaaagcgac tacactagca gatgcaaaag catatttttt
    11281 ccagtttttc atgataaaaa ctcctttttt tatttttaaa cttataaaca atgtaatgat
    11341 cttatactca atgaaaatca aagagcaaac tagaaaacta gccgcaggct gtacttgagt
    11401 acggcaaggc gacgttgacg cggtttgaat ttgattttcg aagagtatta acttcacaca
    11461 agggaagttg ggaactgaga aatgttattt ctcaataagc actattcttt cacaccaccg
    11521 atagtcaaac cttttacaaa gtagcgttgg aagaatggat acaaaatcgc gattggaagg
    11581 gttgcaacca caaccatggc catacgacct gtttctttcg gtagagcaac tcccagttga
    11641 ccagtcaagc cgaccgcttt ggcaatgtag tccatatttt gttggatttg catgagcaaa
    11701 tattgcaatg gatacaagtt gtcactcttg atataaagaa gggcgttgaa ccagtcattc
    11761 cagaaaccaa gagctgtcaa aagcgtgatg gttgcgatac ctggtagtga caatggcaaa
    11821 cagatttgga agaaaatccg ggcctcactg gcaccatcga tacgagccga ttcgagaatg
    11881 gcttctggaa tggtcttctt gaagaaggaa cgcatcaaga tgatgttaaa gggggagaga
    11941 agcattggca caatcaaggc ccaaacagtg tcaccaagct gaagtacacg ggtcaccatg
    12001 atataacctg gtaccaaacc agcgttgaac aacatactga gaaggacgaa gatggtaaaa
    12061 aatctgcgat acttaaaggt tgtccgtgaa atagcgtagg cataggttgt tgtgataaag
    12121 acatttgtca atgtcccaac tacggttaca aagacagaga tgaagagggc ttgtaggatt
    12181 ttatccttaa actgtgccaa aaactcaaaa ccgtctaagc caaattggga tgggaagaag
    12241 ctatagccgt attggaggag gcttttctcg tctgtcactg aaataatgat aacgaataca
    12301 aaaggtagga tacaagagag ggcaatcaaa cccgaaatga tactgaagaa gatatctgct
    12361 ttcttactga aggagtgaat gccgacatta tcaatttttt cttttttaat tttctttttt
    12421 gccatattct cctcctttct agaacaaagc tgagtttgga tcgactcgtc ttgcaagcaa
    12481 gtttgatagg ataaccagaa tcaaaccaac aacggattgg taaagaccgg ctgctgcagc
    12541 cataccgata tctgctgtct gagtcaaacc attaaagaca tatacatcca aaacgttggt
    12601 tacattgtaa agctgaccag cattgtgtgg gatttgatag aagagaccga agtctgcgcg
    12661 gaagatattt ccgactgcaa ggatggtcaa tacagttaca agcggagtca actgaggaat
    12721 ggttacgttg cgaatacgtt gccacttgct agctccgtcc actgtcgctg cttcgtagta
    12781 ggttggatca attcccatga tcgtcgcata gtacatgaca ctgctatatc caaagccttt
    12841 ccaaatacct aggaaaagta ggagataggg ccagatgccc aggtcagcgt agaaattgac
    12901 ttctttgaga ccaagacttt ccaatagatg attgaacacc cctttatcaa tatttaggaa
    12961 ggcatctgta aagaaactga tgataaccca agacaagaag taagggaaca acatagaagt
    13021 ttgaaaaatc ttcaccattc tcttagaacg gagctcgctg aggataatgg caatccctac
    13081 agatacaact aaacctagaa agataaagcc aagattgtag aggacagtat ttcgtgtgat
    13141 aataaaggcg tctcttgaac taaataagaa tctgaaatta tcgagtccga cccatttact
    13201 atttatgata ctatctatga aaccattact ggtcatgtgg tagtctttga aggcaaccac
    13261 gttcccaaat actggaatgt aaaagaatag aatcaaccag agtgcccctg gcaaaaccat
    13321 caagagaaag atccagttgt ctctcaatgt ttttgaaaac tttttcataa tttcctccct
    13381 ttttattttg atatccatct aaaaattctt ttttagactt ttgataacga ttacattatt
    13441 agtatactcc tatttgcagg ttaggttaaa ctcctaatta tagaaaaaac tccacaaatt
    13501 atgtagcaga tttaaaactt tatcaccact atcaaacaaa tgtcctaaat caattgttta
    13561 ttttatctct attagcccag tgatggcgtc actctgttat aagcatccaa caacggggta
    13621 tactgaaaaa tctccagact agggaactca gcgatagttc ctaatctgga gatttttaat
    13681 atgttattag gcgtttgctt tcaacttagc aataacctct ttaagattat caatcacctc
    13741 tgcttcagta tgctcagagc ctttttcatc tgccaagaac aaaactgctt tttgaagttc
    13801 tttttgagag ttttcaagga catccttatc tactgtttca aggtttgagt ctttaagaag
    13861 tttacttaat tccttggcta atttcttgag tttgatttgc agactcatct tctcctgctg
    13921 tttctttgcc cgctgtttgt cctccatcct tagttgctga ctggctttcc ttaatggact
    13981 ctagggaagc aatggcatct ttgactgttt gcaagatatc acgtaaacct tgctctgtca
    14041 aactatcatc tgcaaaagct ttcttagcct ctgccaaaac cagacgtgct gaatctgtgg
    14101 taggattcga tacacctgtc aatgatctca aaagattttc taaggtttga gtctgcttac
    14161 taatactaga ctaaaatcaa aaagcattat ataacagtga tatgaaatca actaaagaag
    14221 aaatccaaac catcaaaaca cttttaaaag actctcgtac agctaaatat cataaacgcc
    14281 ttcaaatcgt tctatttcgt ctgatgggca aatcttataa agagattata gagcttttat
    14341 agtgatttga aataagatgt gaacaactct atcaggaaag tcaaattaat ttatagaaat
    14401 attttagcag ccaaggtgta ctgttataga ttcaatacac t
//
LOCUS       DAVHTH010000048        13892 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.048, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000048 DAVHTH010000000
VERSION     DAVHTH010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13892)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13892)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13892
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.048"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            complement(1..219)
                     /locus_tag="VVR63_001579"
                     /pseudo
     CDS             complement(1..219)
                     /locus_tag="VVR63_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(281..730)
                     /locus_tag="VVR63_001580"
     CDS             complement(281..730)
                     /locus_tag="VVR63_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEU6129582.1"
                     /translation="MTLTTFLLQAVASFLAIITFLIVLNVQRSMLLPGGILGMTVWLI
                     YLLLKEPTNVIVATFIAAIIGSCVSQILSILYKTPAVVFILAILAPLVPGYLSYRTTA
                     FFVTGDYNKALASATLVVMLALVISIGMASGTVILRLYHYIKTHRVS"
     gene            complement(732..1490)
                     /locus_tag="VVR63_001581"
     CDS             complement(732..1490)
                     /locus_tag="VVR63_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEU6129583.1"
                     /translation="MEESKELNAVIDVIMLAGTILLKSGSEIHRVEDTMIRIAHSQGI
                     VDCNVLAMPAAIFFSIENTNISRMKRVTSSSYNIEKVCDVNQISRQLVGGQIDLETAF
                     KQLTALQAKPLPYTKLQVTLAATFSAPFFSVMFSGNIYDALGAGVATLFGFAFSLYVE
                     KFIRIPFVTAFAGAFVFGIIAQFWARYTGFPSTADLIIAGAVMPFVPGIALTNAVRDI
                     MTNHINSGMSKMFESLLITLALGAGTSVALVLMN"
     gene            complement(1605..3584)
                     /gene="pknB"
                     /locus_tag="VVR63_001582"
     CDS             complement(1605..3584)
                     /gene="pknB"
                     /locus_tag="VVR63_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HEU6129584.1"
                     /translation="MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVL
                     RTNYQTDPIAVARFQREARAMADLDHPHIVRITDIGEEDGQQYLAMEYVAGLDLKRYI
                     KEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSVIAENPSVPQALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYN
                     RRNESKLIFDETSKADTKTLPKVSQSTLTSIPKVQAQTEHKSIKNPSQAVTEETYQPQ
                     APKKHRFKMRYLILLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKATLKKANF
                     EIGEEKTEASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSD
                     VIAELKEKKVPDNLIKIEEEESNESEAGTVLKQSLPEGTTYDLSKATQIVLTVAKKAT
                     TIQLGNYIGRNSTEVISELKQKKVPENLIKIEEEESSESEPGTIMKQSPGAGTTYDVS
                     KPTQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVTTAPAGSVE
                     GMVVEQSPRAGEKVDLNKTRVKISIYKPKTTSATP"
     gene            complement(3581..4321)
                     /locus_tag="VVR63_001583"
     CDS             complement(3581..4321)
                     /locus_tag="VVR63_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HEU6129585.1"
                     /translation="MEISLLTDVGQKRTNNQDYVNHYVNRAGRTMIILADGMGGHRAG
                     NIASEMAVTDLGVAWVDTQIDTVNEVREWFAHYLEIENQKIHQLGQDEAYRGMGTTLE
                     VLAIIDNQAIYAHIGDSRIGLIRGEEYHQLTSDHSLVNELLKAGQLTPEEAEAHPQKN
                     IITQSIGQKDEIQPDFGTVILESGDYLLLNSDGLTNMISGSEIRDIVTSDIPLADKTE
                     TLVRFANNAGGLDNITVALVSMNEEDEE"
     gene            complement(4336..5649)
                     /gene="rsmB"
                     /locus_tag="VVR63_001584"
     CDS             complement(4336..5649)
                     /gene="rsmB"
                     /locus_tag="VVR63_001584"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HEU6129586.1"
                     /translation="MTKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLLAADKG
                     LVTELVYGTVARKLTLEWYLSHFIEDRDQLDSWLYVLLLMSAYQLRYLDKIPDHAVVN
                     EAVELAKLRKKGSEKLVNALLRRILREGWPDIASIKRKNKRDSIAYSLPVWLVAKLKE
                     EYGEERAKAIFESLLVRNKASIRVTDLSRKEEIQALLEANDSLLATTGLVKEQGHFAG
                     HNLFADGAITIQDESSQLVAPTLDLQGDERVLDACAAPGGKTAHIASYLTTGQVTALD
                     LYDHKLDLIQENAQRLGVEDRVQTQKLDARKVHEFFDQDSFDKILVDAPCSGIGLLRR
                     KPDIKYNKETADFASLQEIQLEILGSVCQILGKGGIITYSTCTIVSEENFQVVKAFLE
                     SHPEFEQVKLEHECKDIMKDGCILITPELYGSDGFFISQFRKISD"
     gene            complement(5642..6577)
                     /locus_tag="VVR63_001585"
     CDS             complement(5642..6577)
                     /locus_tag="VVR63_001585"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HEU6129587.1"
                     /translation="MTKLIFMGTPDFSATVLKGLLTDDRYEILAVVTQPDRAVGRKKV
                     IQETPVKQAAKEAGLSIYQPEKLSGSPEMEELMKLGADGIVTAAFGQFLPSKLLDSMD
                     FAVNVHASLLPRHRGGAPIHYALIQGDEEAGVTIMEMVKEMDAGDMISRRSIPITDED
                     NVGTLFEKLALVGRDLLLDTLPAYIAGDIKPEPQDTSQVTFSPNIKPEEEKLDWNKTN
                     RQLFNQIRGMNPWPVAHAFLKGDRFKIYEALPVEGQGNPGEILSIGKKELIVATAEGA
                     LSLKQVQPAGKPKMDIASFLNGVGRTLTVGERFGD"
     gene            complement(6590..8986)
                     /locus_tag="VVR63_001586"
     CDS             complement(6590..8986)
                     /locus_tag="VVR63_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HEU6129588.1"
                     /translation="MALAKIIVDVPLMQTDQPYSYRIPEEFEGMLEVGMRVHVPFGKG
                     NRLIQGIVLGLESQSDGEEMEQDLKDIAEVLDFSPVLTPEQLWLAEELRKSVFSYKIS
                     ILKAMLPGFLNSSYDKILYPLEGLSQEERVRLFGSEDSLAFSSLDLAKQAEMMRLTRK
                     GLLGLEYQAVDQKKVKTQSWYEVDHAQLEGVEISTRAKKKLELRDYLLSHPESASLAS
                     LLESYSREQVNFFVDQGAVTIVQKEVQRSAAYFEGIEASRPLELNPEQRQARDAVVSS
                     IGSSQPPFLLQGITGSGKTEVYLQIIQGALDKGKTAILLVPEISLTPQMTERFIARFG
                     DKVAILHSGLSNGEKYDEWRKVERGDAQVVVGARSAIFAPLKNLGVMIIDEEHEVAYK
                     QDSNPRYHARDVAILRAQYNQATLVLGSATPSLESRARAGKGVYQHLRLTQRANPLAT
                     IPEVQVIDFRDYIGQNETSNFTPPLLEAIQDRLVKKEQVVLMLNRRGYSSFVMCRECG
                     TVDTCPNCDISLTLHMDTKTMNCHYCGFSKDIPQVCPNCKSRSIRYYGTGTQKAYDEL
                     AELFPQARILRMDVDTTRKKGSHQALLDQFGRGEADILLGTQMIAKGLDFPNVTLVGV
                     LNADTALNLPDFRSSERTFQLLTQVAGRAGRAEKAGQVLIQSYNSQHYAIRFAKDQDY
                     EGFYAYEMGIRRQLGYPPYYFTIGITLSHKKEEEVFKRAYEVMNILRSGLSETSPILG
                     PTPKPIARTHNLYHYQILIKYRLEDELGPTLNQVLALTQERENSELRLSIDHEPQQFL
                     "
     gene            complement(9052..9366)
                     /locus_tag="VVR63_001587"
     CDS             complement(9052..9366)
                     /locus_tag="VVR63_001587"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HEU6129589.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILEAKRAHELEAGAPATQGFKSE
                     KSTLRALEEIESGNVTIHPDPEGKREAVRRRIEEEKRRKEEEEKKIKEQIAKEKEDGE
                     KI"
     gene            complement(9391..10017)
                     /gene="gmk"
                     /locus_tag="VVR63_001588"
     CDS             complement(9391..10017)
                     /gene="gmk"
                     /locus_tag="VVR63_001588"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HEU6129590.1"
                     /translation="MADRGLLIVFSGPSGVGKGTVRREIFESSENQFQYSVSMTTRAQ
                     RPGEVDGVDYFFRTREEFEELIRQGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKKKVPDAVFIFLTPPDLDELQDRLVGRGTDSAEVIAQRIEKAKEEIALM
                     REYDYAIVNDQVPLAAERVKCVIEAEHFCVDRVIGHYQEMLPKSPTTR"
     gene            complement(10147..11760)
                     /locus_tag="VVR63_001589"
     CDS             complement(10147..11760)
                     /locus_tag="VVR63_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HEU6129591.1"
                     /translation="MEIMSLAIAVFAVIIGLVIGYVSISAKMKSSQEAAELMLLNAEQ
                     EATNLRGQAEREADLLVNEAKRESKSLKKEALLEAKEEARKYREEVDAEFKSERQELK
                     QIESRLTERATSLDRKDDNLTSKEQTLEQKEQSISDRAKNLDAREEQLEEVERQKEAE
                     LERIGALSQAEARDIILAQTEENLTREIASRIREAEQEVKERSDKMAKDILVQAMQRI
                     AGEYVAESTNSTVHLPDDTMKGRIIGREGRNIRTFESLTGVDVIIDDTPEVVTLSGFD
                     PIRREIARMTMEMLLKDGRIHPARIEELVEKNRQEIDNKIREYGEAAAYEIGAPNLHP
                     DLMKIMGRLQFRTSYGQNVLRHSIEVAKLAGIMASELGENAALARRAGFLHDIGKAID
                     HEVEGSHVEIGMELARKYKEPPVVVNTIASHHGDVEAESVIAVIVAAADALSAARPGA
                     RSESLESYIKRLHDLEEIANGFEGVQTSFALQAGREIRIMVNPGKIKDDKVTILAHKV
                     RKKIENNLDYPGNIKVTVIRELRAVDYAK"
     gene            complement(11830..12120)
                     /locus_tag="VVR63_001590"
     CDS             complement(11830..12120)
                     /locus_tag="VVR63_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000451507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEU6129592.1"
                     /translation="MEVEEKSIELSYEYVDDGYSGSNFERPNFKNMIDDLNKGKFSII
                     MVKDLSRFGRDYIESGKYLQKIFPEKGIRFISVNDNYDSDNADVSDIHLRFV"
     gene            complement(12243..13001)
                     /locus_tag="VVR63_001591"
     CDS             complement(12243..13001)
                     /locus_tag="VVR63_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6129593.1"
                     /translation="MKFKNYLFDLYPYFPKGFSLDNREDPDVCSKALYDDLCKMFFDD
                     DSKEKLKITSVCNKCQNYGNRDYYTLFIDKDKYLLSSDYIGASIYWAQEAGLNDRIIL
                     DHLSISRTIGGHILFPRGGKLETVNQARGGEKGYYDRFDLTLYAIKEWFVENKNTKIG
                     YAIENYHEWFELFSGDDNCKNGFENFVEFFKLEGFIYEQNKIIDLIKSDLENNQVVFL
                     DKEDILIASTEEEYIRYMKNLNIIILERTKKILL"
     gene            complement(13017..13157)
                     /locus_tag="VVR63_001592"
     CDS             complement(13017..13157)
                     /locus_tag="VVR63_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000899899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6129594.1"
                     /translation="MLFYLTKELNSGVKKIGTISTTLVVVAGVSAGVLGGKFDFKFPK
                     KI"
     gene            complement(13111..13614)
                     /locus_tag="VVR63_001593"
                     /pseudo
     CDS             complement(13111..13614)
                     /locus_tag="VVR63_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370715.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="KilA-N domain-containing protein"
BASE COUNT         3818 a         3240 c         2588 g         4246 t
ORIGIN      
        1 taccagaatc attcgctaat tgttttttta ggacaattga tttgtacttc cgtcgcatca
       61 atcattaccg tgtcttcaga actgagagga gttcttgaaa tcgtaacacc acctttgaac
      121 aagagttact tcaacccatt ggctccgacg gagtaagttg ctttcgtgga taccaaaatc
      181 agccgcaatt tcttcataag tgcggtattc tcgcacatat agaaagcgtt gttaatttat
      241 ttatctcatt tttcagaaaa ttcttttatt tctgtaaagt ctacgatact cgatgtgttt
      301 ttatataatg atacagtctg agaatcactg ttccgctagc cattccaata gagattacca
      361 aagccaacat gacaaccaag gtcgcacttg ccagtgcttt attatagtcc cctgtcacaa
      421 aaaaggcagt tgttcggtag gagagataac ctggaaccag cggtgccaaa atggccaaga
      481 taaagaccac agcaggtgtc ttataaagaa tacttaaaat ctggctgaca caagaaccaa
      541 taatggctgc aatgaaggta gctacaatga cattggtcgg ttccttgagc aagagataga
      601 ttagccagac agtcatgccc aaaatccctc caggtaagag catagaccgt tgcacattga
      661 gtacgattaa aaaagtgata atggcaagaa aacttgctac tgcttgtaat aaaaaggttg
      721 ttagtgtcat attagttcat caataccaag gcgacagaag ttcctgcccc taaagcgagg
      781 gtaatgagca gggattcaaa catcttactc ataccagagt ttatgtggtt ggtcataata
      841 tcacggaccg cattggtcaa ggcaatacct ggtacaaacg gcatgaccgc accagctata
      901 atcaaatctg ccgttgaagg aaaacctgtg tagcgagccc aaaactgggc aattatccca
      961 aagacaaagg ctccagcaaa ggctgtcaca aagggaattc ggataaattt ttccacatag
     1021 agggaaaagg caaaaccaaa taaggtcgcc actcctgccc caagtgcgtc gtagatattt
     1081 ccgctaaaca taactgaaaa gaaaggagca ctaaaggtcg cagccagagt tacctgcaac
     1141 ttagtatagg gaaggggttt ggcttgcaag gccgtcaatt gcttaaaggc tgtttctaag
     1201 tcaatctgcc ccccaactag ctgacgagaa atctggttca catcgcagac tttttcgatg
     1261 ttataagaag aggaggtcac gcgcttcatg cgcgaaatat tggtattttc aatagagaaa
     1321 aagatagcgg caggcatggc aaggacattg caatccacaa tcccctgcga atgcgcgatt
     1381 cgaatcatgg tatcttctac acgatggatt tctgagccac ttttaaggag aatagtcccc
     1441 gctagcataa tcacatcaat gacggcattt aattcttttg attcttccat gctttcctcc
     1501 ttttatcaac tccctctatt ctatcacaaa tccggactca aaaaaaatct ttgccatgaa
     1561 atcatgacaa agattgatta ctcattttga ttatccatct gcttttaagg agtagctgaa
     1621 gttgttttag gtttgtagat tgaaatcttg actctagtct tatttaggtc taccttttca
     1681 cctgctctag gactttgttc aacaaccatg ccttctacac tacctgcagg cgctgtcgtc
     1741 acttctacaa cttctatatt agcttcctta atcccaacaa tttgaatcaa attgttctta
     1801 gtaaactcca agctggaacc aatgtaactc ggcatggcaa cacttgtaac ttttttagct
     1861 actgtcaaga caatttgagt aggtttactc acatcataag tcgttccggc acctggactt
     1921 tgtttcataa tcgttcctgg ttcgctttcg ctggactctt cttcctctat cttaatcaaa
     1981 ttctcaggaa ccttcttctg cttgagttct gagattactt ctgtagagtt ccgtccaata
     2041 tagttcccta attgaatcgt cgtagctttt ttagctactg tcaaaacaat ttgagttgcc
     2101 ttgctcaagt cataggtcgt accttctggt agactttgct tcaagaccgt tccagcctca
     2161 ctctcattgg actcttcttc ctcaatttta atcaaattat ctggaacttt tttctctttt
     2221 aattccgcga taacatcaga agatttccgg ccgacataat tactaatttg gaaggattgt
     2281 ttgcctgatg agacaaccag attgattttc gttccttctt ttcgaccagt tccagcgcca
     2341 ggatctgtac ggataatccg cccttcttcc accttttcac tagcctctgt cttctcctca
     2401 ccaatctcaa aattggcttt tttgagcgtt gccttggcct ctgcaactgt ctgacctgcc
     2461 acatccggaa tggcaatggt tgcaggagtt ctggataaga tccaaataag agaagctgcc
     2521 accaatacaa ggctggccaa caaaatcagg taacgcatct taaatctatg ttttttcggt
     2581 gcttgtggtt ggtaagtttc ctctgtcaca gcctggcttg ggtttttgat tgatttgtgt
     2641 tctgtctgcg cttgaacctt aggaatagat gtcaaggtac tctgagaaac cttcggcaag
     2701 gtcttggtat ctgccttgct cgtttcatca aagattaact tactttcatt tctacgattg
     2761 taggacaagc tactagacaa gtccacatac atctctgaaa ccgatcggta gcgattggtc
     2821 aactttttag cagttgcctt gataataaca ttttctaaag cctgaggtac agatggattt
     2881 tctgcaataa cggacggcag gggtttctgg aaatgctgga gggcaatggt caccgcgcta
     2941 tccccgtcat aagggatatg gcctgtcaac atctcataga aaataatccc catggcatag
     3001 atatcactct gcacagtcgc cttagaacca cgcgcctgct ctggtgacaa gtaatgaact
     3061 gagcccaaca tcgagttagt ctgggtcaga cttgtctctg caaaggctac agcaatccca
     3121 aagtctgtga ccttggcagt cccatctggt gtcaaaagga tattttgagg tttcaagtcc
     3181 ctgtgaacaa ttcctcgagt atgggccaag cgcatagcca agagaatttg tcccatgata
     3241 cggacggctt cttcattaga aagaggataa tgttccttga tatagcgttt gaggtctagt
     3301 ccagcaacat actccattgc aagatactgt tgaccgtctt cctcaccaat atctgttatc
     3361 cgaacgatat gaggatggtc tagatctgcc atagctctcg cttcacgctg aaaacgagct
     3421 acagctatcg ggtccgtctg gtagttggtc ctcagaacct tcactgccac ttcttcccca
     3481 tctaagatta agtctttggc taggtaaaca tccgccatgc ctcctcgacc aatctgtttg
     3541 acaatccgat agcgtccggc aaaaatcttg ccgatttgga tcattcttca tcctcctcgt
     3601 tcatagaaac aagggcaacc gtaatgttgt ctaaacctcc tgcattgtta gcaaaacgaa
     3661 caagtgtctc cgttttatct gctaaaggaa tatcactggt tacaatatca cgaatctcac
     3721 tgcctgaaat catgttggtc aagccgtcac tattgagcaa gagatagtcg cctgactcaa
     3781 ggataactgt cccaaaatca ggctgaattt catctttttg cccaatagac tgggtgataa
     3841 tatttttttg cggatgagct tctgcctctt ctggtgtcaa ttgaccagcc ttgagcaatt
     3901 cattaaccaa ggaatgatcg ctcgtcaact gatggtattc ttctccacga atcaagccga
     3961 tacgcgaatc accaatatga gcatagatag cctgattatc aataatagca aggacttcca
     4021 aagtagttcc catgcctctg taagcttcat cctgaccaag ctggtgaatc ttttgatttt
     4081 caatttctag gtaatgggcg aaccattcac gcacttcatt gactgtatcg atctgggtat
     4141 caacccaagc tacacccagg tctgtgaccg ccatttcact agcgatattc cctgcacgat
     4201 gacctcccat cccatcagct aaaataatca tggtacgtcc agctctattg acatagtggt
     4261 tgacatagtc ttggttattt gttcgtttct gaccaacatc tgttaataat gaaatttcca
     4321 tgtgtcagtt ccttcctaat ccgatatctt gcgaaattga ctgatgaaga atccatcact
     4381 tccatacaat tcaggtgtaa tgaggataca gccgtctttc atgatatcct tacattcatg
     4441 ttctagtttt acctgctcga actcgggatg actctctaaa aaggccttaa cgacttgaaa
     4501 attctcctct gagacgatag tgcaggtgct ataagttatt ataccacctt tgcctagtat
     4561 ttgacaaaca ctacctaata tttctaactg aatttcctgc aaggacgcga aatctgccgt
     4621 ttctttattg tatttgatat ctggttttcg gcgcaaaaga ccgattcctg aacaaggagc
     4681 atccaccaaa atcttatcaa aggaatcctg gtcaaaaaac tcatgcacct ttctggcatc
     4741 caatttttga gtttgaaccc gatcttcaac tcccagacgt tgggcatttt cttgaattaa
     4801 atccaacttg tggtcgtaca agtccagagc agtaacctga cctgtcgtaa gataagaggc
     4861 tatatgggct gttttcccac ctggagccgc acaggcatca agcactcgct catcaccttg
     4921 taaatcaagc gtcggagcaa ccagctgact ggactcgtct tggatggtaa tggctccatc
     4981 cgcaaacaaa ttatgccctg caaaatgccc ctgctcctta accagaccag tggttgctaa
     5041 aagggaatca ttcgcctcca acaaggcttg gatttcctct tttcgactta ggtctgttac
     5101 acgaatactg gctttgtttc gcactaacag gctttcaaag atggcttttg ctctctcctc
     5161 tccgtattct tccttgagtt tggcaactag ccaaactggg agagaatagg caatggagtc
     5221 acgcttgttt tttcgcttga tgctagcaat atctggccag ccttcacgca agatacggcg
     5281 aaggagggca ttgaccaatt tttcactgcc ttttttacga agtttggcca attccactgc
     5341 ttcattgacc acagcatgat ctggaatctt gtccaaatag cggagttggt aggcactcat
     5401 gagaagaagg acatagagcc agctgtctaa ctggtctctg tcttcgataa agtgggatag
     5461 gtaccattcc agagtcagtt tacgggctac cgttccatag accagctcgg tcactaagcc
     5521 cttgtctgct gccaaaagtt gactcccctt tagatgctta tttaaggcga tatttgagta
     5581 tgcttggttc acaaaaacat cctctagcac tgctagagct aaacttctag ccgtttctac
     5641 tttagtcacc aaatcgttct cctacagtca atgtacgtcc aactccgttg aggaaggaag
     5701 caatgtccat cttaggctta ccagctggct gcacttgttt gagggataga gccccttcag
     5761 ccgttgcgac aatcaattct ttcttgccga tagagagaat ctcacctgga tttccctgac
     5821 cttctactgg tagggcttca taaatcttaa agcggtcgcc cttaaggaaa gcatgggcaa
     5881 caggccaggg gttcattcca cgaatttggt taaagagttg acgattggtt ttgttccagt
     5941 ccagtttttc ttcctctggc tttatatttg gagagaaggt aacctgactc gtatcctgcg
     6001 gttcaggttt gatatcacca gcaatatagg caggcagagt gtccaaaagc aaatcacgac
     6061 caactagcgc caatttttca aacaaggtgc caacattgtc ctcatctgtg atcggaatgc
     6121 tgcgacgaga aatcatatct cctgcatcca tttccttaac catttccatg atggtcacac
     6181 cagcttcctc atccccttga atcaaggcat aatggatagg cgcaccacca cggtgtctag
     6241 gaaggaggga ggcatgaacg ttgacagcaa agtccatgct atcaaggagt ttgcttggga
     6301 gaaactgccc aaaagcagca gtcacaattc catctgctcc tagcttcata agttcttcca
     6361 tctctggact tccagataat ttttcaggtt ggtagataga tagtcctgct tccttggcag
     6421 cctgcttgac tggggtttct tggataactt ttttacgacc aacagcacgg tctggctggg
     6481 tcacaacggc tagaatttcg taacggtcat ctgtcaaaag tccttttaag actgttgctg
     6541 aaaagtcggg ggtccccata aagattagtt ttgtcatatc ttctccttct tataaaaatt
     6601 gctgcggctc atggtcaatg ctgagacgga gctcactatt ttcccgttct tgagtcaagg
     6661 ccaagacctg gttgagggtc ggccccagct catcttctaa acggtattta attaaaatct
     6721 ggtaatgata gaggttgtgg gtacgggcaa tcggttttgg cgttggcccc agaatgggac
     6781 tggtctctga caagcctgac cgcaaaatgt tcatgacttc ataggcacgt ttgaaaacct
     6841 cttcttcttt cttgtgagaa agggtaatac caatcgtgaa atagtaaggt ggatagccga
     6901 gttgtcgtct gattcccatt tcataggcat aaaagccttc gtaatcttga tccttggcaa
     6961 atcgaatagc atagtgctgc gaattgtagg actgtatcaa gacttgacct gctttttcag
     7021 cccgacctgc tcgacctgcc acctgagtca agagctggaa ggttctctca gaagaacgga
     7081 aatcaggcag attcaaggcc gtatccgcat ttagaactcc gactagggta acattgggaa
     7141 aatccaaacc ctttgcaatc atctgagtac caagtaaaat atccgcttcc cctcgcccaa
     7201 actggtcaag caaggcttgg tgactgcctt tctttcgagt cgtatccaca tccatcctca
     7261 aaatgcgagc ttggggaaag agttctgcta gctcatcata agccttctga gttcccgtcc
     7321 catagtaacg aatactgcgg ctcttacagt taggacagac ctgaggaata tccttcgaga
     7381 aaccacaata atggcagttc atagtcttgg tatccatatg caaggtcaga gaaatatcgc
     7441 agttgggaca agtatccacc gtcccacact cccgacacat gacaaagcta gaataaccac
     7501 ggcgattgag catgagaacc acctgctctt ttttaaccag acggtcttgg atagcctcta
     7561 gcaaaggagg cgtaaagttt gacgtctcat tttgtccgat atagtctcga aagtcaatca
     7621 cttgaacctc agggattgta gccaaaggat tagcacgttg ggttagacgt aagtgttgat
     7681 agacgccttt gccagcacgt gcccggctct ctaagctcgg cgttgcagat ccaagtacca
     7741 gagttgcttg attatactga gcccgtaaaa tagctacatc tctggcatgg taacggggat
     7801 tgctgtcctg cttataagcc acttcatgct cttcatcaat aatcatgaca cccagatttt
     7861 tcagaggagc aaagatagca gatctggcac caacaacaac ttgggcatcg ccacgctcca
     7921 ccttgcgcca ttcatcatac ttttcaccat tggataatcc tgagtgaaga atggctacct
     7981 tgtccccaaa acgtgctata aaacgctcgg tcatctgagg agtcaaggaa atctcaggta
     8041 ccagcaaaat agctgtcttg cccttatcca gggcaccttg gataatctgc aagtaaacct
     8101 cggtcttccc acttcctgta atcccttgaa gtagaaaggg aggttgagaa ctgccaatag
     8161 aactcacaac cgcatcacgc gcctgtcttt gttctggatt taactccaaa ggtctacttg
     8221 cttcaattcc ttcaaaataa gcagccgagc gttgaacttc cttttggact atggtaacag
     8281 caccttgatc cacaaagaag ttgacttgct ctcgcgagta ggactctaac aagctagcca
     8341 aggaagcgct ctctggatga gacagcagat aatctctcag ttccaacttt ttcttggcac
     8401 gtgtagaaat ctcaacacct tctaattgag catggtcaac ctcataccaa gactgggtct
     8461 tgaccttctt ttgatcgact gcctgatatt ccagaccaag caggcctttt ctagtcaaac
     8521 gcatcatttc agcttgcttg gcaaggtcta gtgaagaaaa ggctagcgaa tcttctgaac
     8581 caaacaggcg cactcgttct tcctgactca agccttccag aggatagaga atcttgtcat
     8641 agctagaatt cagaaatcct ggaagcatgg ccttgaggat agaaattttg taggagaaga
     8701 cagatttgcg taactcctca gccagccaga gttgttctgg cgtgagaaca ggagaaaaat
     8761 ccagcacctc tgcaatatct tttaaatctt gctccatctc ttctccatct gattgggact
     8821 ccaaaccaag aacaatccct tgaatcaggc gattcccctt accaaaaggc acatgaaccc
     8881 gcatcccaac ttccagcatt ccctcaaatt cctccggaat cctgtaacta tagggctggt
     8941 ccgtctgcat caagggcaca tctacgataa tcttagctag ggccatcgtc tcacctcctc
     9001 cttgtcagta cattcttgca atagaaaaaa taagattgag tccccccaac cttaaatttt
     9061 ttcaccatct tctttttctt tagcaatttg ctctttgatt ttcttttctt cttcttcttt
     9121 gcggcgtttt tcttcttcga tacggcgacg cactgcttca cgttttcctt ctggatctgg
     9181 gtgaattgta acgtttcctg attcgatttc ttctaaagcg cgaagagttg atttttcaga
     9241 cttaaaacct tgagttgctg gggcacctgc ttccaattcg tgggcacgtt ttgcttccaa
     9301 gattacgagt gaatattttg aaggaacctt gtcgagcaag gtatcaatag agggttttaa
     9361 catcatttgc ttgtacctat tttctaaatt ttatcgggta gttggagatt ttggtaacat
     9421 ctcctgatag tgaccaatga cacgatccac acagaagtgt tctgcttcaa tcacacattt
     9481 gacacgttca gcagctaggg gtacctgatc gttgacaatc gcataatcat actcacgcat
     9541 gagggcaatt tcttccttgg ccttttcgat tcgttgggca atcacttctg cactatctgt
     9601 tccacgacct accaagcgat cttgcaattc atccaaatct ggtggtgtca ggaagataaa
     9661 gacagcatct ggaacctttt tcttgacctg aagagcaccc tgaacttcaa tttcaaggaa
     9721 aacatcgatt cccttgtcca aggtttcatt gacataggtc agaggagttc catagtagtt
     9781 gccgacatat tctgcgtatt ccaacatctg tccttgacga atcagctctt caaattcttc
     9841 acgagtacgg aagaaatagt caacaccgtc cacttctcca ggacgttgtg cgcgtgtcgt
     9901 catcgataca gaatattgaa attggttttc agaactctca aaaatctctc ttctaaccgt
     9961 tccttttcca acccctgaag gaccagaaaa aacgattagt aagcctcggt ctgccattgt
    10021 gtctcctttt agtcaatctg tgaaataaca tttctctaga ataatggcaa aaagccagat
    10081 tatcctttac agtctttcta tctagtgtaa caaaaaagca gtaatttttc aactgctctt
    10141 tcttatttat ttagcataat ctactgcacg aagctcgcga atcacggtta ccttgatatt
    10201 tcctggataa tcgagattgt tttcaatttt cttacgaact ttgtgagcca agattgtgac
    10261 tttgtcgtcc ttgatttttc ctggattgac catgatacga atttcacgtc ctgcttgaag
    10321 ggcaaagcta gtttgcactc cttcaaagcc gttagcaatt tcttccaaat catggagacg
    10381 cttgatgtag ctttcaagag actcactacg agcacctgga cgggctgcgc tcaaggcatc
    10441 tgctgcagcg acgataactg ctatcacgct ctcagcttca acatctccgt ggtgactagc
    10501 aatcgtattc accacaactg ggggttcctt gtacttacgg gccaattcca taccgatttc
    10561 aacgtggcta ccttcaacct catggtcaat ggctttcccg atatcgtgaa ggaatccagc
    10621 acgacgggca agagccgcat tttcaccaag ttcgctcgcc atgataccag ccaacttagc
    10681 aacctcaatc gaatggcgca aaacattttg tccatatgaa gtacggaact gcaaacgtcc
    10741 cataatcttc atcaagtctg gatgaaggtt tggcgcacca atttcatagg cagcagcctc
    10801 accgtattca cgaatcttat tgtcaatctc ttgacggttt ttctcaacca actcttcgat
    10861 acgagctgga tgtatacgac catctttgag caacatttcc atagtcatac gggcaatctc
    10921 acgacgaatc ggatcaaatc ctgacaaggt caccacttct ggtgtatcgt cgataatcac
    10981 atcgacccct gtcaaacttt caaaggtacg aatgttacga ccttcacgac caataatgcg
    11041 tcccttcata gtatcgtctg gcagatgaac tgttgagttt gttgactccg ctacatattc
    11101 accagcgata cgttgcatag cttgaaccaa gatgtccttg gccattttgt cagaacgttc
    11161 cttgacctct tgctcagctt cgcgaatgcg actggcaatc tccctggtca agttttcctc
    11221 tgtctgagcc aagataatat ctcgtgcttc tgcctgagac agagcaccaa tacgctctag
    11281 ttctgcttct ttttgtcttt cgacttcctc taattgctct tcacgcgcat caaggttttt
    11341 cgctctatca gaaatacttt gttctttttg ttcaagtgtt tgttctttac tcgtcaaatt
    11401 gtcgtcctta cggtcaaggc tagtagctct ctctgtcaaa cgactttcga tttgtttgag
    11461 ttcttgacgt tctgatttga attcagcgtc cacttcttca cggtattttc tggcttcttc
    11521 tttggcctcc aatagtgctt cttttttaag agacttgctt tcacgtttgg cttcattaac
    11581 aagtaaatcc gcttcacgct cagcttgtcc acgtaaatta gttgcttctt gttcagcatt
    11641 taaaagcatc aactctgcag cttcctgaga tgatttcatc ttagctgaga tgctgacata
    11701 tccaatgact aaaccaatga tgacggcaaa aacagcaatc gcaagcgaca tgatttccat
    11761 gtttttacct cattttattg ttattccgaa tgacatacat tcttttacat tctaccataa
    11821 aaaaagaatt taaacaaacc ttaaatggat atcgctaaca tccgcattat cactatcata
    11881 gttatcattt acagatataa agcgaatacc tttttcagga aatatctttt gtaagtactt
    11941 tcctgactcg atataatctc tgccgaaacg agataaatct tttaccataa tgatagaaaa
    12001 ctttccttta ttcaggtcat caatcatatt cttaaaattt ggtcgctcaa aattagaacc
    12061 actatatcca tcatctacat attcatagga taattcaata gatttctctt ctacctccaa
    12121 aaagcaaaaa ggataaattt cccctacact ttaatagtga aaatttatcc ctcttggtaa
    12181 gctcttttat taattttttt gataaagaaa acgcacattt tatttaactg gtgctgaaat
    12241 ctttataata aaattttttt ggttctttct agaataatga tattaagatt tttcatatat
    12301 cttatatatt cttcttctgt gctagcaatc aaaatatctt ctttatctaa aaagacaacc
    12361 tgattgttct ctaaatctga tttaattaaa tctataattt tattttgctc atatataaat
    12421 ccttctaact tgaaaaactc gacaaagttc tcaaatccat ttttacaatt atcatcacca
    12481 gaaaatagtt caaaccattc atggtaattc tctatagcat aacctatttt tgtattttta
    12541 ttttccacaa accattcttt tatagcatat agtgttaaat caaaacgatc ataatatcct
    12601 ttttctccac ctctagcctg attaacggtt tctaattttc cacctctagg gaaaagaatg
    12661 tgtccaccta ttgttcttga aatactcaaa tgatctaaaa ttattctgtc gtttaatcct
    12721 gcctcttgtg cccaataaat agaggctcct atataatcac ttgataataa atacttatcc
    12781 ttatcaataa ataaagtata ataatctcta tttccatagt tttggcattt attacataca
    12841 gatgttattt taagtttttc ttttgaatca tcatcaaaaa acatcttaca taaatcatcg
    12901 tacaacgcct tactacatac atcaggatcc tctctattat ctaatgaaaa acctttggga
    12961 aaataaggat ataaatcaaa tagataattt ttaaacttca tatttattat tctccattaa
    13021 atctttttag gaaatttaaa gtcaaatttt cctccaagca cacccgcact tactcccgca
    13081 actactacaa gtgttgtact aattgttcct attttcttca cgccactgtt tagctctttt
    13141 gttaaataaa acaacattga tcatatctgc ttcacttaca tacttgtaag acaactgttc
    13201 gttggtaaga tcttttaaga gatattcttt gattgcatct gtatgaattt tgtagttaat
    13261 cttagaaatt tctctattca aattccagcc taatgatagc ttagaatttt aatctgactt
    13321 aagtcttttg taatcctgaa ttacatacat cttaaattca gcagaaatac ataaagcaaa
    13381 ttcaaaggca atatctgtat gtgcaaatgc accaccatat cttccacctt ttgagataat
    13441 tccgattgct ccagttttct ctacccattt cttaggagac aatgtaaatg aattatatcc
    13501 agcttccgat ttaattcggt cgaattcgac cgaattgaaa ttcatgttat ttaagctttt
    13561 ccataaacca agaaactcaa ttgtatcttt tcttctcatc caatttttaa ttacatcact
    13621 cgatacttat ccgaacgata agctccacgt aaggtgttcg caatcgacca aactgcattg
    13681 actacatttg aaatctgaac atcgttcgac tggaatatcg gtagtttttc tttaaaatta
    13741 gacatttgct tcccctgttt ttatgattta caattctctt cattatacca caaaataggc
    13801 gctttgtcaa ctgtagtggg ttgaagtcag ctaagctcga gaaaggacaa atttcgtcct
    13861 ttcttttttg atgttcaaag cgataaaaat cc
//
LOCUS       DAVHTH010000049        13479 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.049, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000049 DAVHTH010000000
VERSION     DAVHTH010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13479)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13479)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13479
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.049"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            complement(128..640)
                     /locus_tag="VVR63_001594"
     CDS             complement(128..640)
                     /locus_tag="VVR63_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001275913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin"
                     /protein_id="HEU6129595.1"
                     /translation="MSAQITINHKKARYVRIELEGYNALSLAEVEVFRFIATNGETAI
                     QVSKSVQPISQTPVKDKTLTIQHSGAYIARYSITWEEVTVDKDGNQVVRSHSWEGNGR
                     NQTAGFVLNLPIKENMRNLRVKIEKKTGLLWNRWQTIYENRPILAQPHRKITHWGTTL
                     NSKVSDDDVL"
     gene            complement(665..1239)
                     /locus_tag="VVR63_001595"
                     /pseudo
     CDS             complement(665..1239)
                     /locus_tag="VVR63_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000445853.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
     gene            complement(1249..1644)
                     /locus_tag="VVR63_001596"
     CDS             complement(1249..1644)
                     /locus_tag="VVR63_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topology modulation protein"
                     /protein_id="HEU6129596.1"
                     /translation="MLDSKEELKESENDAPKLETPLREEPRLAPQTLPEASEVLENKR
                     EESKVEITEPAQADDIRKVVGELAKDISITKLYMTGHSLGGYLAQIAAVEDYQKYPDF
                     YNHVLRKVTTFSAPKVITSRTVWDAKNGF"
     gene            complement(2120..2929)
                     /locus_tag="VVR63_001597"
     CDS             complement(2120..2929)
                     /locus_tag="VVR63_001597"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEU6129597.1"
                     /translation="MTFLNKIHETATFLKEKGIAAPEFGLILGSGLGELAEEIENPVV
                     VDYAEIPNWGRSTVVGHAGKLVYGELAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKV
                     LGCEGVIVTNAAGGIRFGPGTLMAISDHINMTGQNPLMGENLDDFGPRFPDMSRAYTP
                     EYRATAHEVAKKLNIKIDEGVYIGVTGPTYETPAEIRSYKTLGADAVGMSTVPEVIVA
                     AHSGLKVLGISCITNFAAGFQEELNHEEVVEVTERVKGDFKGLLKAILAEL"
     gene            complement(2945..3487)
                     /locus_tag="VVR63_001598"
     CDS             complement(2945..3487)
                     /locus_tag="VVR63_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HEU6129598.1"
                     /translation="MTRYALLVRGINVGSKNKVVMAELHQELTNLGLEKVESYINSGN
                     IFFASIDSKAQLVEKLETFFAVHYPFIQSFSLLSLEDFEAELENLPAWWSRDLARKDF
                     LFYTEGLDVDQVIATVESLELKDEVLYFGKLGIFWGKFSEESYSKTAYQKYLLKVPFY
                     RHITIRNAKTFDKIGQMLKK"
     gene            complement(3489..4700)
                     /locus_tag="VVR63_001599"
     CDS             complement(3489..4700)
                     /locus_tag="VVR63_001599"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HEU6129599.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDANNFVNAGVPDGASDTLGHISK
                     TVGLNVPNMAKIGLGNIPRETPLKTVAAESNPTGYATKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWNGFPEEILTKIEEFSGRKVIREANKPYSGTAVIDDFGPRQMETGELII
                     YTSADPVLQIAAHEDIIPLDELYRICEYARSITLERPALLGRIIARPYVGEPGNFTRT
                     ANRRDLAVSPFSPTVLDKLNEAGIDTYAVGKINDIFNGAGINHDMGYNKSNSHGIDTL
                     LKTMGLAEFEKGFSFTNLVDFDALYGHRRNAHGYRDCLHEFDERLPEIIAAMRENDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSPAFKGNGLIPVGHFADISATVADNFGVETA
                     MIGESFLDKLV"
     gene            complement(4714..5397)
                     /gene="rpiA"
                     /locus_tag="VVR63_001600"
     CDS             complement(4714..5397)
                     /gene="rpiA"
                     /locus_tag="VVR63_001600"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HEU6129600.1"
                     /translation="MENLKKMAGIKAAEFVKDGMVVGLGTGSTAYYFVEEIGRRIKEE
                     GLQIIAVTTSSVTTKQAEGLNIPLKSIDQVDFVDVTVDGADEVDSQFNGIKGGGGALL
                     MEKVVATPSKEYIWVVDESKLVEKLGAFKLPVEVVQYGAEQVFRRFERAGYKPSFREK
                     DGQRFVTDMQNFIIDLALDVIENPIAFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGV
                     QISTSKKGK"
     gene            complement(5695..6534)
                     /locus_tag="VVR63_001601"
     CDS             complement(5695..6534)
                     /locus_tag="VVR63_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HEU6129601.1"
                     /translation="MKVIDQALLEKVIIERSRTSHKGDYGRLLFLGGTYPYGGAIIMA
                     ALAAVKSGAGLVTVGTDRENIPALHSHLPEAMAFSLQDQQLLKEQLEKAEVVLLGPGL
                     RDDAFGEDLVKQVFAGLRQNQILIVDGGALTILARTSLSFSSSQLILTPHQKEWEKLS
                     GITIEKQKEDATASALTSFPQGTILVEKGSATRIWQAGQSDYYQLQVGGPYQATGGMG
                     DTLAGMIAGFAGQFKQASLYERVAVATHLHSAIAQELAQEQYVVLPTEISNCLPKVMK
                     RYV"
     gene            complement(6548..7369)
                     /locus_tag="VVR63_001602"
     CDS             complement(6548..7369)
                     /locus_tag="VVR63_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATPase"
                     /protein_id="HEU6129602.1"
                     /translation="MILKIYNREYSLQWDGIYYLALIDYPNIQEWELEKIAKFIAYEK
                     LHKRQTSIECADSCLKKEILDYICQHPFLPPFTPTDKRVASTYDLHKRLVTSDYCSHT
                     TTIDAAISIFKTDQLLSAVKAFRRDAEELVLDSRNAASDPIDYFDYVMLGWSNTSSGY
                     RLAMERLLGRAPSEKELQDKFIPGVSFHFIYTDLIKVTGYIFDGYHVAKIKDMLNLFS
                     ELYICIIPTHNKSQFENIIPTKIQDRVHYLDYAGEDLEEWTKKVYQVVLKQSDKG"
     gene            complement(7506..8363)
                     /locus_tag="VVR63_001603"
     CDS             complement(7506..8363)
                     /locus_tag="VVR63_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HEU6129603.1"
                     /translation="MTQIIDGKALAAKLQGQLAEKTAKLKEETALVPGLVVILVGDNP
                     ASQVYVRNKERSALAAGSRSEVVRVPETITQEELLDLIAKYNQDPAWHGILVQLPLPK
                     HIDEEAVLLAIDPEKDVDGFHPLNMGRLWSGHPVMIPSTPAGIMEMFHEYGIELEGKN
                     AVVIGRSNIVGKPMAQLLLAKNATVTLTHSRTHNLAKVAAKADILVVAIGRAKFVTAD
                     FVKPGAVVIDVGMNRDENGKLCGDVDYEAVAPLASYITPVPGGVGPMTITMLMEQTYQ
                     AALRTLDRK"
     gene            complement(8517..9251)
                     /locus_tag="VVR63_001604"
     CDS             complement(8517..9251)
                     /locus_tag="VVR63_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU6129604.1"
                     /translation="MTETLIKIENLHKSFGKNEVLKGINLEIKRGEVVVIIGPSGSGK
                     STLLRSMNLLEEATKGKLIFEGVDITDKKNDLFAMREKMGMVFQQFNLFPNMTVMENI
                     TLSPIKTKGESREVAEKRAQELLEKVGLPDKADAYPQSLSGGQQQRIAIARGLAMEPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAREVADRVIFMADGVV
                     VEDGTPEQIFEQTQEQRTKDFLSKVL"
     gene            complement(9251..9934)
                     /locus_tag="VVR63_001605"
     CDS             complement(9251..9934)
                     /locus_tag="VVR63_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001011621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU6129605.1"
                     /translation="MNFSFLPKYLPYFNYGAVVTILISICVIFLGTILGVVLAFGQRS
                     KFKPLVWLANLYVWIFRGTPMMVQIMIAFALMHINAPTIQIGILGVDFSRLIPGILII
                     SMNSGAYVSETVRAGINAVPKGQLEAAYSLGIRLKNAMRYVILPQAVKNILPALGNEF
                     ITIIKDSSLLSAIGVMELWNGATTVSTTTYLPLTPLLFAAFYYLIMTSILTVALKAFE
                     KHMGQGDKK"
     gene            10124..10354
                     /locus_tag="VVR63_001606"
     CDS             10124..10354
                     /locus_tag="VVR63_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HEU6129606.1"
                     /translation="MESHLVRIINRLEAMANDGGNLKRNFEREGVVVAEVAYSHDEEN
                     GPIFTLRDVEDRETYTFDSIDLIAMEIYELLY"
     gene            10583..12841
                     /locus_tag="VVR63_001607"
     CDS             10583..12841
                     /locus_tag="VVR63_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEU6129607.1"
                     /translation="MLCQNCKINDSTIHLYTNLNGKQKQIDLCQNCYKIIKTDPNNSL
                     FKGMTDLNNRDFDPFGDFFNDLNNFRPSSNTPPIPPTQSGGGYGGNGGYGSQNRGSAQ
                     TPPPSQEKGLLEEFGINVTEIARRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGEP
                     GVGKTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEI
                     RKREDIILFIDEIHEIVGAGSASDGNMDAGNILKPALARGELQLVGATTLNEYRIIEK
                     DAALERRMQPVKVDEPTVDETITILKGIQKKYEDYHHVQYTDAAIEAAATLSNRYIQD
                     RFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKSQATREEDFEKAAYFRD
                     QIAKYKEMQKKKITDQDTPIISEKTIEHIIEQKTNIPVGDLKEKEQSQLIHLAEDLKS
                     HVIGQDDAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSA
                     DSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRHNPYSLILLDEVEKAHP
                     DVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKTEASVGFGAAREGRTNSV
                     LGELGNFFSPEFMNRFDGIIEFKALSKDNLLQIVELMLADVNKRLSSNNIRLDVTDKV
                     KEKLVDLGYDPKMGARPLRRTIQDYIEDTITDYYLENPSEKDLKAVMTSKGNIQIKSA
                     KKAEVKSSEKEK"
     gene            complement(13048..13479)
                     /locus_tag="VVR63_001608"
                     /pseudo
     CDS             complement(13048..13479)
                     /locus_tag="VVR63_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
BASE COUNT         4048 a         3016 c         2409 g         4006 t
ORIGIN      
        1 tagtttgctc tttgattttc attgagtatt aattttgttc tttcacagag agctacctga
       61 gttctattca agctcaggta gtactttctt ataaactaga caaactaact gtcattgtac
      121 catcagatta caagacatca tcgtcactca ccttggaatt caatgtcgta ccccaatggg
      181 taattttacg gtggggttga gctaaaattg gtctgttttc atagattgtt tgccatctat
      241 tccatagtag gcccgtcttt ttctcaatct taactcgcag atttctcata ttttctttga
      301 ttgggaggtt gaggacaaaa cctgcagtct ggttgcgacc gtttccttcc caagaatgac
      361 tacgaacaac ttggtttcca tctttatcta ctgtaacttc ttcccaagtt atggagtagc
      421 gggcaatgta agctccactg tgttgaattg tcaatgtttt atctttcaca ggagtctgac
      481 tgattggttg aactgactta gaaacttgta tcgccgtttc accattcgta gctataaagc
      541 ggaaaacttc aacttctgca agactgaggg cattatagcc ttctagctca atccgaacat
      601 agcgcgcttt tttatggtta atcgtaattt gtgctgacac atctttagga gatattatac
      661 gttttcactc aatttcttta ccagaaccgt ctaaaagaat gacatcaaag tttgccaatc
      721 tatcctgggc agtgtctgtt cggttgtaaa tattgatttg gcgaatggtt tcttctttag
      781 ccaaatctac ttgccaccaa ggcttagatt ggaagtttgt atgagtgaca gaattgtgac
      841 catagttacc atcgactttg ccatccacag ctcttctagc attcctccga aagctgtcga
      901 actttgagta acctgttttc ctaaggcaat attttccatt ggttcagcgc ttggttgact
      961 agaagattga ggtagagcct gtttcttaaa gaatcgcgct ttatccaatt tcggatcacg
     1021 ataaccatgt ttatccaagg tagcttgttt accaatatta aagttaggaa tatcattcat
     1081 tggactttca aaatagccac gagaacggtg tttaaagcgt gaattacctg taaatgtaac
     1141 aatatcacga ttattatgaa tcaagggagt cacaacattg tcattatcaa ccacataatg
     1201 cttaattttt ccactaacag ctaatttacg actttccaaa ccaacatctc agaaaccatt
     1261 cttagcatcc caaacagttc tggaagtaat cactttagga gcactgaaag ttgtcacttt
     1321 cctcaataca tggttataaa aatcaggata tttttggtaa tcttcaaccg ctgcaatctg
     1381 agctaggtag cctccaagag aatgacctgt catatacaac ttagtaatac ttatatcctt
     1441 ggctaattcc ccaacaacct tgcggatatc atccgcttga gctggctctg ttatctctac
     1501 ttttgactct tcccttttgt tttcaagaac ttcacttgct tccggaagcg tttgaggagc
     1561 tagtcttggc tcctctctaa gaggagtttc tagttttgga gcatcatttt ctgactcttt
     1621 caattcctcc ttagaatcta gcacacctat taccacttca gatgttacat cttgctttac
     1681 ttcattggct gaaattccag ctggagctag aaatcaaagc cgactacaac agatacaact
     1741 ccgatactta attttttatg ccaaagcgca taattcgttg accaattttc attatttctt
     1801 atctttcttt tcgtttattt acaagcagac tcaagcgaaa tctcattgtg ctatatatga
     1861 taagactgag aaattcagaa agtcaattca ttctcatctc tccttatcat actagtctgc
     1921 ttggctagga agctaatgct agtatcctag aatcttgtct ttcacaatgc tggctatcag
     1981 atcagacaca cctattcttc cgcttctttc agttataaga gcaggaagaa gctcatagta
     2041 ttcctctgtt tcttctttaa tacggatagg cagtcaatcc tgaaaagaca gaggcactcc
     2101 cccttttaaa tcttttttct tacaattcag caagaatcgc tttaagcaag cctttgaaat
     2161 cacctttaac acgttcagtc acttctacaa cttcttcgtg attgagttct tcttggaaac
     2221 cagccgcaaa gttagtgata catgaaattc ccagaacttt caagccagag tgggctgcca
     2281 cgataacttc aggaaccgta gacataccaa ctgcatctgc tcccagtgtc ttataggaac
     2341 gaatttctgc tggtgtttca taagtcggac cagtaactcc gatatagaca ccttcatcaa
     2401 tcttgatatt aagtttttta gccacttcat gggcagtggc acgatattct ggtgtgtagg
     2461 ccctagacat atctgggaaa cgtgggccaa agtcatccaa gttttcaccc atcaatggat
     2521 tttgccccgt catgttgata tggtctgaga tagccatcaa ggtaccagga ccaaatctga
     2581 taccgccagc tgcattggtt acaataacac cttcacatcc aagaactttc atcacacgaa
     2641 ctgggaaagt caccacttcc agaggattcc cttcatagaa atggaaacgc ccttgaagag
     2701 ccaagacctt gcgacctgcc agttcaccat ataccaattt accagcatga ccgactactg
     2761 ttgaacggcc ccagtttgga atctcagcat agtctactac aactggattt tcgatttctt
     2821 ctgccaattc tccaagtcct gacccaagga ttagaccgaa ctcaggggct gcaattccct
     2881 tttctttcag gaaagtagca gtttcatgga ttttgtttaa aaatgtcatt gtgtgtctcc
     2941 tttattattt ttttagcatt tgaccaattt tgtcaaaggt tttagcatta cgaatagtaa
     3001 tgtggcggta gaaaggcacc ttcagcaagt acttctgata ggcagtctta gaataggatt
     3061 cttcagaaaa tttcccccag aaaatcccaa gttttccaaa ataaagcact tcatctttca
     3121 gctctaaact ttcaactgtc gcgatgactt ggtccacatc caaaccctca gtgtaaaaga
     3181 gaaaatcttt tcgtgccaag tctctgctcc accaagctgg tagattttca agttccgcct
     3241 caaagtcctc tagactcagt aaagaaaagc tctgaataaa tggataatgg actgcaaaga
     3301 aagtctctag cttttcaacc aattgggctt tggaatctat cgaagcaaag aaaatattgc
     3361 cactgttgat gtagctctca accttttcca gtcccaagtt tgtcaattct tgatgaagct
     3421 ccgccatgac gaccttattc ttactaccaa cattgatacc tctcaccagc aaagcatagc
     3481 gcgtcatctt ataccaattt atctaagaaa ctttccccaa tcatagcagt ttccacacca
     3541 aagttatcgg caacagtcgc tgaaatatct gcaaaatgtc ctactggaat gagaccattt
     3601 cctttaaagg cagggctata ggccaacaat ggaatatatt cccgagtgtg atccgttcct
     3661 gcatacgttg ggtcatttcc atggtccgca gtaatcaaga gaaggtcatt ctctctcata
     3721 gctgcgataa tttcaggtaa gcgttcatca aactcatgca agcaatcacg gtaaccgtga
     3781 gcattacgac gatggccgta aagggcatca aagtcaacta ggtttgtgaa tgagaatcct
     3841 ttttcaaact cagcaagtcc catagtcttc aatagtgtat caattccatg actatttgac
     3901 ttgttgtaac ccatgtcatg gttgatacca gcaccgttaa agatatcgtt gattttaccc
     3961 acagcataag tatcgatacc agcctcattc aatttatcca aaacagttgg ggaaaatgga
     4021 gatacagcca agtcacgacg gtttgccgta cgagtgaagt tacctggttc acctacataa
     4081 gggcgagcaa tgatgcgacc aagaagggca ggacgctcaa gggtaatcga acgagcgtat
     4141 tcacagatac ggtacaattc atccaaagga ataatgtctt cgtgggcagc aatctgcaaa
     4201 acagggtcag ctgaagtata gataatcaac tctccagttt ccatctgacg tggtccaaaa
     4261 tcatcgataa cagccgttcc tgaataaggt ttgttggctt cacgaataac cttgcgtcct
     4321 gagaattctt cgatttttgt caggatttct tctgggaatc cgttccagaa agtatcgaaa
     4381 ggctcagtaa tgttgagtcc catgatttcc cagtgtccag tcatagtatc cttaccaaga
     4441 gatacttcct ctaattttgt tgcatatcca gttggattgc tttcagctgc tacagtctta
     4501 agaggagttt cacgaggaat atttccaaga cctattttag ccatgtttgg gacattcaaa
     4561 ccaactgttt ttgaaatgtg tcccagtgtg tcagaagctc catctggaac ccctgcattg
     4621 acaaagttat tagcatctgg tgctgcaccg attcctacag aatccagtac caccaaatga
     4681 atacgattaa atttagacat cttatgcccc cttctatttt cctttttttg aagttgaaat
     4741 ctgaactcca tcccgtccag caacgatgac cttatccacc atttggttga ataaaccatg
     4801 ctccacaaca ccaacgacat ggtccaattc ttgtccaaaa gcaattggat tttcaatgac
     4861 atccaaggcg aggtcaatga taaaattctg catatccgtc acaaaacgtt ggccgtcttt
     4921 ttcacggaaa cttggtttgt agccagctcg ttcaaaacga cgaaagacct gttctgcacc
     4981 atactgaacc acttctactg gcaatttaaa agcacctagt ttttcgacca gcttgctttc
     5041 atccaccacc caaatgtatt cttttgatgg tgtcgcaaca accttctcca tcagaagagc
     5101 accaccacca cctttgattc cattaaactg actatccact tcatctgcgc catcaactgt
     5161 cacatcgaca aagtctactt ggtcaataga tttgagtggg atattaaggc cttctgcctg
     5221 tttagtggtc acactagaag tcgttacagc tataatctgc aatccttctt ccttgatacg
     5281 acgaccgatt tcttcgacaa aataataggc agtcgagcct gttccaagtc caacgaccat
     5341 tccatccttg acaaactcag cagccttgat acctgccatt ttcttcagat tttccactca
     5401 aacacctcca ttaaagagct acctctatta taccatgtaa aggcttttat ttcatctaaa
     5461 agtaccttta gaatactgct tatttatcct tgaaattaaa tttttttaat aaaagcagaa
     5521 ctctgacaaa tcactttaag tacggatgta aaccaaatca actctaacaa aaatagattt
     5581 acaagagtaa aaaaacgaac aaatttagtt tcttagcgag aagaatacta aacgttcgtt
     5641 ttttgtaaat taagaataat gatacaaatt atcaatattt tttgtctaac tattttagac
     5701 atatcttttc attactttag gaagacaatt actaatctcc gttggcaaaa ccacatactg
     5761 ttcttgagct agttcttggg ctatggctga atgaagatgg gtcgctactg ccacacgttc
     5821 gtaaagacta gcttgcttaa actggcctgc aaatcctgca atcatcccag caagcgtatc
     5881 tcccattccc ccagtcgcct gatagggacc gccaacctgt aactggtaat aatctgattg
     5941 gccagcttgc caaatacgag tagctgaacc tttctccacc aaaattgttc cttgagggaa
     6001 ggaagttagg gcactagccg ttgcatcttc cttttgcttt tcaatcgtaa ttccagataa
     6061 tttttcccat tctttttggt gaggagttag gataagctgg cttgaggaaa atgacaaact
     6121 tgtcctagca agaatggtca aggcacctcc gtctacaatc aaaatctgat tttgtcttaa
     6181 gccagcaaag acctgtttaa ctagatcttc tccaaaagca tcgtctcgta aacccggccc
     6241 cagcaagaca acttctgcct tctccaattg ctcttttaac aactgctggt cttgaagaga
     6301 aaaggccata gcctcaggta aatggctgtg cagggctgga atattttccc tatctgttcc
     6361 aacggtcacc aatcctgcac cgctttttac agctgccaaa gcagccatga tgatggcacc
     6421 accataagga taagttccac caagaaacag cagacggcca tagtctcctt tatgactagt
     6481 acgagaacgt tcaataataa ctttttctag taaggcttga tcaatcactt tcatcgttct
     6541 tcctcaacta tcctttatct gattgtttta aaacaacttg atagactttc ttagtccact
     6601 cttctaagtc ttctccagca tagtcaagat aatgcaccct atcttgtatt ttagttggaa
     6661 taatattttc aaattggctc ttattatgag ttggaataat acaaatatac aactcactaa
     6721 ataaattcaa catgtcctta atttttgcaa catggtagcc atcaaaaata taaccagtaa
     6781 ctttaatcaa atctgtatag ataaaatgaa aactcactcc aggaataaac ttgtcttgta
     6841 attctttctc tgaaggagct cgacctaata aacgctccat cgctaatcga taaccagaac
     6901 ttgtatttga ccaccctaac atgacataat caaaataatc tatcggatcc gatgcagcat
     6961 ttctactatc caaaaccaac tcttcagcat ctcgcctaaa ggctttcaca gcagataaga
     7021 gctgatctgt tttaaagata gaaatcgctg catctatagt cgtagtatga ctacagtagt
     7081 ctgaagtcac taacctctta tgtagatcat aagtcgaggc tactctttta tctgtagggg
     7141 taaatggtgg cagaaaggga tgctgacaga tgtaatctaa aatttctttt tttaaacaag
     7201 aatcagcaca ctcaatactt gtttgacgtt tatgaagttt ttcgtaagct ataaatttag
     7261 caattttttc taattcccac tcttgaatat ttggataatc aattagtgct aggtagtata
     7321 ttccatccca ttgtaaacta tattccctat tataaatttt taaaatcatc taatcacctc
     7381 actccattat acaacaaaaa ggaggcgcag acctcctttt gtaatcttat atctaaaatt
     7441 taatattcat ttctgccatt ttaaatatag ctatagaaaa tacactctct tcagcgattt
     7501 ttctcttatt ttctatccaa tgtccgaagt gctgcttgat aagtttgctc catcagcata
     7561 gtaatggtca tagggccgac acctccaggg actggcgtaa tatagctagc aagtggggca
     7621 actgcctcat aatccacatc cccacagagc ttaccatttt catcacgatt catcccaacg
     7681 tcaatgacta ccgcacctgg tttgacaaag tcagcagtca caaacttggc acgaccgatt
     7741 gcgaccacca gaatatctgc tttagcagcc accttagcaa gattatgggt gcgtgagtgg
     7801 gtcaaagtca ctgttgcatt cttggccaaa agaagctgag ccatgggttt tccaacgata
     7861 ttagaacgac cgatgacaac cgcattttta ccttctaatt caatcccata ttcatgaaac
     7921 atttccataa ttcctgcagg tgttgatgga atcatgactg gatgtccaga ccaaaggcgt
     7981 cccatattta gaggatggaa accatccaca tccttttctg ggtcaatagc caatagaacc
     8041 gcctcttcat caatgtgttt tggtaatggc aactgaacca aaatcccatg ccaagctgga
     8101 tcctgattgt atttagcaat caggtctaac aattcctctt gagtaatggt ctctggaact
     8161 cgcactactt cgctacggga accagccgca agagctgacc tctccttgtt gcgaacgtag
     8221 acttggctgg ctggattatc cccaaccaaa atcactacca aaccaggcac tagagctgtt
     8281 tcttccttta attttgcagt cttttcagcc aactgcccct gcaatttggc cgctaaagct
     8341 ttcccatcaa taatctgtgt catatcactt ctcttttctt tcaaatatct tccattatac
     8401 caaaaactgc tagtgccctc taacacttct ttcctaggtt atcctatagt ttcaaactat
     8461 aagaaaaagc tctggttgaa cttttcacta atcttgtctt gaaattttaa aatagattat
     8521 aaaaccttac tcaagaaatc tttagtccgt tgttcttggg tttgttcaaa aatctgctca
     8581 ggtgtcccat cttcaacaac cacaccgtct gccataaaga taacacgatc tgccacctca
     8641 cgggcaaatc ccatctcatg tgttacgata accatagtca tccctgactt ggcaaggtct
     8701 tgcataacag ccaatacctc acctaccatt tcaggatcca aggctgaagt tggttcgtca
     8761 aagagcaaaa catctggttc catagccaac ccacgcgcga tggcaatccg ttgttgctgc
     8821 ccacccgaca gactctgtgg ataagcgtct gccttatctg gcaaaccaac tttttccaaa
     8881 agctcttggg ctctcttctc agcaacttcc ctgctttcac ctttagtctt gataggtgac
     8941 aaggtaatat tttccatcac agtcatatta ggaaagaggt taaattgttg gaaaaccatg
     9001 cccatcttct cacgcatggc aaacaggtca ttcttcttgt ccgtaatatc gactccctca
     9061 aagataagct tccccttggt tgcttcctcc aacaaattca tagagcgaag caaggtagat
     9121 ttcccactcc ctgaaggacc gatgataacg acaacttctc ctcttttaat ctcgaggttg
     9181 atgcccttca atacttcatt ctttccaaaa gatttatgta aattttcaat ttttatcaag
     9241 gtttctgtca ttatttctta tctccttgtc ccatatgttt ttcaaaagct ttcaaggcta
     9301 ctgtcagaat agaggtcata atcaagtagt aaaatgctgc aaataaaagt ggtgttaaag
     9361 gtagataggt tgttgtagaa actgttgtag ccccattcca caactccatg accccaatag
     9421 ctgataagag ggagctgtcc ttgataatgg tgataaattc gttccccaat gctggcaaga
     9481 tatttttgac tgcttgtggc aaaatcacat aacgcatcgc atttttaaga cgaatcccta
     9541 gcgaataagc cgcctctagc tgaccttttg gaaccgcatt gattccggca cgaacagtct
     9601 ccgaaacata agcaccacta ttcatagaga taatcaaaat ccctggaatc agacgcgaaa
     9661 aatcaacacc taaaattcca atctgaatag tcggagcatt gatatgcata agagcaaagg
     9721 caatcataat ttgaaccatc atcggtgtcc cacggaaaat ccaaacgtac aagttggcca
     9781 accaaacaag cggtttaaac tttgaacgtt gcccaaaagc caagacaaca cccaaaatag
     9841 ttcccaaaaa gataacacag atagaaataa gaatcgtcac aacagcccca tagttaaaat
     9901 aaggtaaata cttaggtaaa aaagaaaaat tcatagtcac actgctttct aaaatagaat
     9961 actgtatgat tataacatgt tttgaattaa aatttaaatt ttttatccaa tttatttaaa
    10021 aatctttaaa ctagcagaat tagcgagaaa tcttagtttt ttctagtcaa gttgccctcc
    10081 tttatggtaa aatagtaacg ataagaaatg aaggagaatc aaaatggaat cacatttggt
    10141 tagaatcatc aaccgccttg aagcaatggc aaacgatggc ggaaatttaa aacgtaattt
    10201 tgaacgcgaa ggagttgttg ttgcagaagt tgcgtacagc cacgacgaag aaaacggccc
    10261 aatctttacc cttcgtgacg tagaagatcg cgaaacgtat acgtttgata gcattgactt
    10321 aatcgcaatg gaaatttacg aacttctcta ctaatctaaa acaagttggg attgtccctg
    10381 catgtctaag taaaatcctt tttgtctcac aaataggatt tttttatagt ccaaattcac
    10441 aaaaattttc attgtaacaa cttctcaaag cttcaatctt tttacttgct ttacacccca
    10501 atcctgttat aatgagagta tagaatttga ctatttttga cctttaaaca agtcaggcta
    10561 aagaaagaaa tgaggtagat gtatgctttg tcaaaactgt aaaattaacg actcaacaat
    10621 tcatctttac accaatctca atggaaaaca aaaacaaatt gacctctgtc aaaactgcta
    10681 taagattatc aaaacagatc ctaacaatag cctcttcaaa ggtatgacgg atctgaacaa
    10741 tcgtgacttc gatccctttg gtgatttctt caatgatcta aacaatttca gaccttctag
    10801 caatactcct cctattcccc caacccaatc aggtggaggt tacggtggaa acggcggtta
    10861 tggttcccaa aatcgtggat ctgctcaaac tccgccacct agccaagaaa aaggcctgct
    10921 ggaagaattt ggtattaatg taactgaaat tgcccgtcgt ggagacattg accccgttat
    10981 tgggcgcgac gatgagatta tccgtgtcat cgagattctc aatcgtagaa ccaagaataa
    11041 tcctgtcctt atcggtgaac ctggtgtcgg aaaaacggcc gttgtcgaag gtctagctca
    11101 gaaaattgtc gatggcgatg tgccacataa actccaaggt aaacaagtca tccgtctgga
    11161 tgtggttagc ttagttcaag gaacggggat tcgaggacaa tttgaagaac gcatgcaaaa
    11221 actcatggaa gaaattcgca aacgtgaaga catcatcctc tttatcgatg aaatccatga
    11281 aattgttggt gctggttctg cgagtgatgg taatatggac gcaggaaata tcctcaagcc
    11341 agcccttgct cgtggagaac tgcaactagt cggtgctact accctcaatg aataccgtat
    11401 cattgaaaag gatgctgccc tcgagcgtcg tatgcagcct gttaaagtcg atgaaccaac
    11461 ggtggatgaa acaatcacta ttctcaaagg gattcaaaag aaatacgaag attaccacca
    11521 cgttcaatat accgatgctg cgattgaagc agctgcaact ctttccaatc gctacatcca
    11581 agatcgcttc ttgcctgaca aggccattga cctcctagat gaagctggtt ctaagatgaa
    11641 cttgaccttg aattttgtgg atcctaaagt aattgatcag cgcttgattg aggctgaaaa
    11701 tctcaagtct caagctacac gagaagaaga ttttgagaag gcggcctact tccgcgacca
    11761 gattgccaag tataaggaaa tgcaaaagaa aaagatcaca gaccaggata ctcctatcat
    11821 cagcgagaaa actattgagc acattatcga gcagaaaacc aatatccctg ttggtgattt
    11881 gaaagagaaa gaacaatctc aactcatcca tctagccgaa gatctcaagt ctcatgttat
    11941 tggccaagat gatgcagtcg ataagattgc caaggctatt cgccgtaatc gtgtcggact
    12001 tggtacccct aaccgcccaa tcggaagctt cctcttcgtt ggaccaactg gtgtcggtaa
    12061 gacagaactt tccaaacaac tggctatcga actttttggt tctgctgata gtatgattcg
    12121 ctttgatatg agtgaataca tggaaaaaca tagtgtggct aagttggtcg gcgctcctcc
    12181 aggttatgtt ggctatgatg aggctggtca attaactgaa aaagttcgcc acaatccgta
    12241 ttctctcatc cttctcgatg aagtggaaaa agctcaccca gatgttatgc acatgtttct
    12301 tcaagtcttg gacgatggtc gtttgacaga cgggcaagga cgcaccgtta gcttcaagga
    12361 tgccatcatt atcatgacct caaatgcagg tacaggaaag accgaagcta gcgttggatt
    12421 tggtgctgct agagaaggac gtaccaattc tgtcctcggt gaactcggta acttctttag
    12481 cccagagttt atgaaccgtt ttgatggcat tatcgaattt aaggctctca gcaaggataa
    12541 cctccttcag attgtcgagc tcatgctagc agatgttaac aagcgcctct ctagcaacaa
    12601 cattcgtttg gatgtaactg ataaggtcaa ggaaaagttg gttgacctag gttatgatcc
    12661 aaaaatggga gcacgcccac ttcgtcggac tattcaagac tatattgagg acacaatcac
    12721 tgactactac cttgaaaatc caagcgaaaa agatctcaaa gcagttatga ctagcaaggg
    12781 aaacattcag attaaatctg ccaaaaaagc tgaagttaaa agttctgaaa aagaaaaata
    12841 aatcctatag aaaaggagta gaaaatgaaa tttttctgct tcttttttta ctaaaataac
    12901 tgtaatttct tgacagcttg ccctttgtcc attatgatat atagtagact gaatctgaaa
    12961 tagtacgaaa caattgctaa aacatttata gaaattaatt ttactttccc aatcgatttg
    13021 ttctcatctt atttcaatct gctatagtca attgaaacaa gaacaagaca aaagagcctc
    13081 ataaaaggta ttgcaacttg gtaatacctt ttatgaggtg ctttttgata tgagcccatg
    13141 ttttctcaat aggattgtac tcaggtgagt aggaaggaag atgtaaaagt ttatacccaa
    13201 actcttcaca caagagttct agcttcccca ttctatggaa tcttgcatta tccataataa
    13261 taaccgatgg tgtggttaat gttggtaaga gaaatttctg aaactaagct tcaaaaaagt
    13321 cgctcgtcat cgtctcttcg taagtcattg gagcgattaa ctcaccattg gttagacctg
    13381 caaccaaaga aatcctctga tatcttcttc cagatacttt gcctcttatt aactgacctt
    13441 ttaatgagcg accatattct cgataaaaat aagtatcga
//
LOCUS       DAVHTH010000050        13403 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.050, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000050 DAVHTH010000000
VERSION     DAVHTH010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13403)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13403)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13403
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.050"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            <1..1778
                     /locus_tag="VVR63_001609"
     CDS             <1..1778
                     /locus_tag="VVR63_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HEU6129608.1"
                     /translation="NYQAYLKTQGIYQTLNIKKIQSLQKIGSWDIGENLSSLRRKAVV
                     WIKTHFPDPMRNYMTGLLLGYLNTDFEEMNELYSSLGIIHLFALSGMQVGFFMNGFKK
                     LLLRLGLTQEKLKWLTYPFSLIYAGLIGFSASVIRSLLQKLLAQHGVKGLDNFALTVL
                     VLFIVMPNFFLTAGGVLSCAYAFILTMTSKEGEGLKAVASESLVISLGILPILSFYFA
                     EFQPWSILLTFVFSFLFDLTFLPLLSILFVLSFLYPVIQLNFIFEWLEGIIRLVSQVA
                     RRPLVFGQPNAWLLILLLISLALVYDLRKNIKGLTVLSLLITGLFFLTKYPLENEITM
                     LDVGQGESIFLRDVTGKTILIDVGGKAESYKKIEKWQEKMTTSNAQRSLIPYLKSRGV
                     AKIDQLILTNTDKEHVGDLLEVTKAFHVGEILVSKGSLKQKQFVVELQATQTKVRSMT
                     VGENLPIFGSQLEVLSPRKMGDGGHDDTLVLYGKFLDKQFLFTGNLEEKGEKDLLKHY
                     PDLKVNVLKASQHGNKKSSSPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGINS
                     KVYRTDQQGAIRFKGWNSWKIESVR"
     gene            1920..2144
                     /locus_tag="VVR63_001610"
     CDS             1920..2144
                     /locus_tag="VVR63_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6129609.1"
                     /translation="MIIGLFQSSISAVTATKSYKYDWNTVLEYSINYHDHQYAWIPEW
                     SRYYSYSEYKVGGGWNYARYEVINYYSGGY"
     gene            2177..2764
                     /locus_tag="VVR63_001611"
     CDS             2177..2764
                     /locus_tag="VVR63_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000939891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6129610.1"
                     /translation="MLQLTHVTLKTRQVILQDADFTFKKGRFYGLLAINGSGKTTLFR
                     AISNLIPISSGNIAVPPSLFYYESVEWLDGNLSGMDYLRLIKNIWKSDLNLRDEIAYW
                     EMADYISLPIRKYSLGMKQRLVIAMYFLSQAKCWLMDEITNGLDEYYRQKFFDRLAQI
                     DRQEQLVLLSSHYKEELVDICDRVVTIHQGQIEEV"
     gene            2768..3949
                     /locus_tag="VVR63_001612"
     CDS             2768..3949
                     /locus_tag="VVR63_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6129611.1"
                     /translation="MKDVSLFLLKKVFKSRLNWIILLLFASVLGVTFYLNSQTANSHS
                     LESRLESRIAANERAINENEEKLSQMSDTSSEEYQFAKNNLDVQKNLLTRKTEILTLL
                     KEGRWKEAYYLQWQDEEKNYEFVSNDPTASSGLKMGVDRERKIYQALYPLNIKAHTLE
                     FPTHGIDQIVWILEVIIPSLFVVAIIFMLTQLFAERYQNHLDTAHLYPVSKVTFAISS
                     LGVGVGYVTVLFIGICGFSFLVGSLISGFGQLDYPYPIYSLVNQEVTIGKIQDVLFPG
                     LLLAFLAFIVIVEVVYLIAYFFKQKMPVLFLSLIGIVGLLFGIQTIQPLQRIAHLIPF
                     TYLRSVEILSGRLSKQIDNVDLNWSMGMVLLPCLIILLLVGILFIERWGSSRKKEVFK
                     V"
     misc_feature    4109..4240
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            4256..4786
                     /gene="infC"
                     /locus_tag="VVR63_001613"
     CDS             4256..4786
                     /gene="infC"
                     /locus_tag="VVR63_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HEU6129612.1"
                     /translation="MKTIAKQDLFINDEIRVREVRLIGLEGEQLGIKPLSEAQALADN
                     ANVDLVLIQPQAKPPVAKIMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPTIDKGD
                     FDTKLRNARKFLEKGNKVKVSIRFKGRMITHKEIGAKVLAEFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPATDKK"
     gene            4819..5019
                     /gene="rpmI"
                     /locus_tag="VVR63_001614"
     CDS             4819..5019
                     /gene="rpmI"
                     /locus_tag="VVR63_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HEU6129613.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAYTSHRFHGKTKKQRRHL
                     RKASMVHSGDYKRIKAMLTRLK"
     gene            5071..5430
                     /gene="rplT"
                     /locus_tag="VVR63_001615"
     CDS             5071..5430
                     /gene="rplT"
                     /locus_tag="VVR63_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HEU6129614.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AVAFTALADAAKAKLGK"
     gene            5488..5868
                     /locus_tag="VVR63_001616"
     CDS             5488..5868
                     /locus_tag="VVR63_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEU6129615.1"
                     /translation="MASKMLHTCLRVENLEKSIAFYQDAFGFKELRRRDFPDHAFTIV
                     YLGLEGDDYELELTYNYDHGPYVVGDGFAHIALSTPDLEALHQEHSAKGYEVTEPNGL
                     PGTTPNYYFVKDPDGYKVEVIREK"
     gene            6118..6918
                     /locus_tag="VVR63_001617"
     CDS             6118..6918
                     /locus_tag="VVR63_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HEU6129616.1"
                     /translation="MNLTCKKRLGVIRLETMKVVAQEEIAPAIFELVLEGEMVEAMRA
                     GQFLHLRVPDDAHLLRRPISISSIDKANKQCHLIYRIEGAGTAIFSTLSQGDTLDVMG
                     PQGNGFDLSDLDEQNQVLLVGGGIGVPPLLEVAKELHERGVKVVTVLGFANKDAVILK
                     TELAQYGQVFVTTDDGSYGIKGNVSVVINDLDSQFDAVYSCGAPGMMKYINQTFDDHP
                     RAYLSLESRMACGMGACYACVLKVPESETVSQRVCEDGPVFRTGTVVL"
     gene            6929..7867
                     /locus_tag="VVR63_001618"
     CDS             6929..7867
                     /locus_tag="VVR63_001618"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HEU6129617.1"
                     /translation="MTTNRLQVSLPGLDLKNPIIPASGCFGFGQEYAKYYDLDLLGSI
                     MIKATTLEPRFGNPTPRVAETPAGMLNAIGLQNSGLEVVLAEKLPWLEREYPNLPIIA
                     NVAGFSKQEYAAVSHGISKATNVKAIELNISCPNVDHCNHGLLIGQDPDLAYDVVKAA
                     VEASEVPVYVKLTPSVTDIVTVAKAAEDAGASGLTMINTLVGMRFDLKTRKPILANGT
                     GGMSGPAVFPVALKLIRQVAQTTDLPIIGMGGVDSAEAALEMYLAGASAIGVGTANFT
                     NPYACPDIIENLPKVMDKYGISSLEELRQEVKESLR"
     gene            7909..9942
                     /locus_tag="VVR63_001619"
     CDS             7909..9942
                     /locus_tag="VVR63_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HEU6129618.1"
                     /translation="MNLGEFWYNKINKNRGRRLMKKVRFIFLALLFFLASPEGAMASD
                     GTWQGKQYLKEDGSQAANEWVFDTHYQSWFYIKADANYAENEWLKQGDDYFYLKSGGY
                     MAKSEWVEDKGAFYYLDQDGKMKRNAWVGTSYVGATGAKVIEDWVYDSQYDAWFYIKA
                     DGQHAEKEWLQIKGKDYYFKSGGYLLTSQWINQAYVNASGAKVQQGWLFDKQYQSWFY
                     IKENGNYADKEWIFENGHYYYLKSGGYMAANEWIWDKESWFYLKFDGKMAEKEWVYDS
                     HSQAWYYFKSGGYMTANEWIWDKESWFYLKSDGKIAEKEWVYDSHSQAWYYFKSGGYM
                     TANEWIWDKESWFYLKSDGKMAEKEWVYDSHSQAWYYFKSGGYMAKNETVDGYQLGSD
                     GKWLGGKATNKNAAYYQVVPVTANVYDSDGEKLSYISQGSVVWLDKDRKSDDKRLAIT
                     ISGLSGYMKTEDLQALDASKDFIPYYESDGHRFYHYVAQNASIPVASHLSDMEVGKKY
                     YSADGLHFDGFKLENPFLFKDLTEATNYSAEELDKVFSLLNINNSLLENKGATFKEAE
                     EHYHINALYLLAHSALESNWGRSKIAKDKNNFFGITAYDTTPYLSAKTFDDVDKGILG
                     ATKWIKENYIDRGRTFLGNKASGMNVEYASDPYWGEKIASVMMKINEKLGGKD"
     gene            complement(10003..11658)
                     /gene="pavA"
                     /locus_tag="VVR63_001620"
     CDS             complement(10003..11658)
                     /gene="pavA"
                     /locus_tag="VVR63_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_094859469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein PavA"
                     /protein_id="HEU6129619.1"
                     /translation="MSFDGFFLHHIVEELRSELVNGRIQKINQPFEQELVLQIRSNRQ
                     SHRLLLSAHPVFGRIQLTQTTFENPAQPSTFIMVLRKYLQGALIESIEQVENDRIVEI
                     TVSNKNEIGDHIQATLIIEIMGKHSNILLVDKSSHKILEVIKHVGFSQNSYRTLLPGL
                     TYIAPPSTESLNPFTIKDEKLFEILQTQELTAKNLQSLFQGLGRDTANELERILVSEK
                     LSAFRNFFNQETKPCLTETSFSPVPFANQVGEPFANLSDLLDTYYKDKAERDRVKQQA
                     SELIRRVENELQKNRHKLKKQEKELLATDNAEEFRQKGELLTTFLHQVPNDQDQVILD
                     NYYTNQPIMIALDKALTPNQNAQRYFKRYQKLKEAVKYLTDLIEETKATILYLESVET
                     VLNQAGLEEIAEIREELIQTGFIRRRQREKIQKRKKLEQYLASDGKTIIYVGRNNLQN
                     EELTFKMARKEELWFHAKDIPGSHVVISGNLDPSDAVKTDAAELAAYFSQGRLSNLVQ
                     VDMIEVKKLNKPTGGKPGFVTYTGQKTLRVTPDSKKIASMKKS"
     gene            11763..12260
                     /gene="ybeY"
                     /locus_tag="VVR63_001621"
     CDS             11763..12260
                     /gene="ybeY"
                     /locus_tag="VVR63_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HEU6129620.1"
                     /translation="MYIEMVDETGQVSKEMLQQTQEILEFAAQKLGKEDKEMAVTFVT
                     NERSHELNLEYRDTDRPTDVISLEYKPELEIAFDEEDLLENPELAEMMSEFDAYIGEL
                     FISIDKAHEQAEEYGHSFEREMGFLAVHGFLHINGYDHYTPEEEAEMFGLQEEILTAY
                     GLTRQ"
     gene            12241..12636
                     /locus_tag="VVR63_001622"
     CDS             12241..12636
                     /locus_tag="VVR63_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HEU6129621.1"
                     /translation="MDSQDNKRKWKNRDLISSLEFAITGIFTAIKEERNMRKHAVTAL
                     VVILAGFVFQVSRIEWLFLLLSIFLVVAFEIINSAIENMVDLASHYHFSMLAKNAKDM
                     AAGAVLVVSLFAVLTGALIFLPRIWDLLF"
     gene            12653..>13403
                     /gene="era"
                     /locus_tag="VVR63_001623"
     CDS             12653..>13403
                     /gene="era"
                     /locus_tag="VVR63_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HEU6129622.1"
                     /translation="MTFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKI
                     MGIYTTDKEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVDTVLFMVPADEARGKGD
                     DMIIERLKAAKVPVILVVNKIDKVHPDQLLSQIDDFRNQMDFKEIVPISALQGNNVSR
                     LVDILSENLDEGFQYFPSDQITDHPERFLVSEMVREKVLHLTREEIPHSVAVVVDSMK
                     RDEETDKVHIRATIMVERDSQKGIIIGKGGAM"
BASE COUNT         4003 a         2395 c         3019 g         3986 t
ORIGIN      
        1 ttaattacca agcctatctg aagactcagg gaatttacca gactctcaat atcaaaaaaa
       61 tccagtcact tcaaaagatt ggcagttggg atataggaga aaacttgtcc agtttacgtc
      121 gaaaggctgt ggtttggatt aagacgcact ttccagaccc tatgcgcaat tacatgacag
      181 gactcttgct gggatatctg aacaccgact ttgaggagat gaatgagctt tattccagtc
      241 taggaattat ccacctcttt gccctatctg gcatgcaggt aggttttttc atgaatggat
      301 ttaagaaact tctcttgcga ttgggcttga cccaagaaaa gttgaaatgg ctgacttatc
      361 ccttttccct tatctatgcg ggactaattg gattttcagc atcggttatt cgcagtctct
      421 tgcaaaagct actggctcaa catggggtta agggcttgga taattttgcc ttgacggtgc
      481 ttgtcctctt tattgtcatg ccaaactttt tcttgacagc aggaggagtc ttgtcctgcg
      541 cttatgcttt tatcctgacc atgaccagca aagaagggga ggggctcaag gctgttgcta
      601 gtgaaagtct agtcatctcc ttgggcatat tgcccattct atccttctat tttgcggaat
      661 ttcaaccttg gtctatcctt ttgacctttg tcttttcctt tctatttgac ttgaccttct
      721 taccgctctt gtctatttta tttgtccttt cctttctcta tccagtcatt cagctgaact
      781 ttatctttga atggttagag ggcattattc gcttggtctc gcaggtggca aggagaccgc
      841 ttgtctttgg tcaacccaac gcatggcttt taatcttatt gttaatttcc ttggctttgg
      901 tctatgattt gaggaaaaac attaaaggat taacagtatt gagtttattg attacaggtc
      961 tctttttcct taccaagtat ccactggaaa atgaaatcac catgctggat gtggggcaag
     1021 gagaaagtat tttcctacgg gatgtaactg ggaaaaccat tctcatagat gtaggtggta
     1081 aggcagaatc ttataagaaa atcgaaaaat ggcaagaaaa gatgacgacc agcaatgcac
     1141 agagaagctt gataccctat cttaaaagtc gaggagtagc taagattgac cagctgattt
     1201 tgacaaatac ggacaaggaa catgtcggag atttgttaga ggtgaccaag gctttccatg
     1261 taggggagat tttagtatca aaaggcagtt tgaagcagaa gcaatttgtg gtagaactac
     1321 aggcgactca aacaaaggtg cgtagtatga cagtagggga gaacttgccc atttttggaa
     1381 gtcagttaga agttctatcc ccaaggaaaa tgggagatgg aggacacgat gataccctag
     1441 ttctgtatgg gaaattcttg gataagcaat ttctcttcac gggaaatttg gaggagaaag
     1501 gagagaagga cttgctgaag cactatccag acttgaaagt aaatgttttg aaagctagcc
     1561 aacatggcaa taaaaaatca tcaagtccag cctttctaga aaaactcaaa ccagagctta
     1621 ctcttatctc agttggaaag agcaatcgaa tgaaactccc ccatcaggaa acattgacac
     1681 gactggaagg tatcaatagc aaagtttacc gaactgacca gcaaggagct atacggttta
     1741 aaggttggaa tagttggaaa atcgaaagtg ttcgatagga aagataaatg ttgtagatta
     1801 gtgaaataaa ctaaaaattt gttgcataat aatgataaaa atggtataat gaaaacgtat
     1861 tcaatactga ggatataaaa tcattaaaaa ttagcaaaaa tcgtttaatt agttagttta
     1921 tgattattgg tctttttcag tccagtatat ctgctgtgac agccactaaa agttacaagt
     1981 atgattggaa tacggttttg gaatatagta tcaactatca cgaccatcag tatgcttgga
     2041 ttccggaatg gtctcgttat tacagctatt ctgagtataa agttggcgga ggctggaact
     2101 acgctcgtta tgaggtcata aactattaca gcggaggcta ttaattctta aagagtgaga
     2161 aaaaggaggg ctagatatgt tgcagcttac tcatgtgacc ttaaaaacgc gacaagtcat
     2221 cttgcaagat gcggatttca cctttaaaaa gggtaggttt tatggtcttc ttgctatcaa
     2281 tggctctgga aagacgaccc tgttccgtgc cattagcaat ttaattccca taagtagtgg
     2341 aaatatcgca gttcctcctt ctttgtttta ttatgagagc gttgaatggc tggatggaaa
     2401 cttaagtggg atggactacc ttcgtctcat aaaaaacatc tggaagtcag acctaaactt
     2461 gagagatgaa atcgcctact gggaaatggc tgactatatc agtcttccca tccgcaagta
     2521 ttccttaggc atgaagcaac gcttggtgat tgctatgtat tttctcagtc aggccaaatg
     2581 ctggctcatg gatgagatta caaatggctt agacgagtat tatcgacaga agttttttga
     2641 taggctagca caaatcgata gacaagaaca gctggttctt ttaagttccc actataagga
     2701 agagttggtt gatatctgcg atagagtagt aaccattcat caggggcaga tagaagaggt
     2761 ttagtttatg aaagatgtta gtctattttt attgaaaaaa gttttcaaaa gtcgtttaaa
     2821 ctggattatc ttacttttat ttgcatctgt actcggtgtt accttttatt taaatagtca
     2881 gactgcaaac tcacacagct tggagagcag gttggaaagt cgcattgcag ccaacgagag
     2941 ggctatcaat gaaaatgaag agaaactctc ccaaatgtct gataccagct cggaggaata
     3001 ccagtttgct aaaaataatt tagacgtgca aaaaaatctt ttgacgcgaa agacagaaat
     3061 tctgacttta ttaaaagaag ggcgctggaa agaggcctac tatctgcagt ggcaagatga
     3121 agagaagaat tatgaatttg tatcaaatga cccgactgct agctctggct taaaaatggg
     3181 ggttgaccgc gaacggaaga tttaccaagc cctgtatccc ttgaacataa aagcacatac
     3241 tttggagttt ccgacccacg ggattgatca gattgtctgg attttagagg ttatcatccc
     3301 aagcttgttt gtggttgcaa ttatttttat gctaacacaa ctatttgcag aaagatatca
     3361 aaatcatctg gacacagctc acttatatcc tgtttcaaaa gtgacatttg caatatcctc
     3421 tcttggagtt ggagtgggat atgtaactgt gctgtttatc ggaatctgtg gcttttcttt
     3481 tctagtggga agtctgataa gtggttttgg acagttagat tatccctacc caatttatag
     3541 cttagtgaat caagaagtaa ctattgggaa aatacaagat gtattatttc ctggcttgct
     3601 cttagctttc ttagccttta tcgtcattgt ggaagttgtg tacttgattg cttacttttt
     3661 caagcaaaaa atgcctgtcc tctttctttc actcattggg attgttggct tattgtttgg
     3721 catccaaaca attcagcctc ttcaaaggat tgcacatctg attcccttta cttacttgcg
     3781 ttcagtggag attttatctg gaagattatc taagcagatt gataatgtcg atctaaattg
     3841 gagcatgggg atggtcttac ttccttgcct gattatcctt ttgttagtgg ggattctatt
     3901 tatcgaaaga tggggaagtt cacgtaaaaa ggaagttttt aaagtttagt tttcctatag
     3961 ggaagctaaa gaaaaactaa catagggaga gaatcaactt ggttctctct ttttgattcg
     4021 aaaaccaaac caaaatataa acacaaactt ttcaaaaaat aactttttat cttgacaaga
     4081 gctagaaaac ttggtatcat ataaaagttg agaaaagcag aagtgagagc ttctcgcctt
     4141 gtgacattaa gttgcctggc cctacggatg aaaagtttcg aagaaacgct atcataacgt
     4201 gcgggcttgt atatttacga gtccgctatt gtttttctct aataaaacaa aagaggtgaa
     4261 aaccatagca aagcaagact tattcatcaa tgatgagatt cgtgtacgtg aagttcgctt
     4321 gattggtctt gagggagaac agctaggcat caagccactc agtgaagcgc aagctttggc
     4381 tgataacgct aatgttgacc tagtattgat tcaaccccaa gccaaaccgc ctgttgcaaa
     4441 aattatggac tacggtaagt tcaaatttga gtaccagaag aagcaaaaag aacaacgtaa
     4501 aaaacaaagc gttgttactg tgaaagaagt tcgtctaagt ccaactattg acaagggtga
     4561 ctttgataca aaacttcgta atgcacgtaa gttccttgaa aaaggaaata aagttaaggt
     4621 atctattcgc tttaagggtc gtatgattac ccataaagag attggtgcaa aagttttagc
     4681 cgagtttgct gaagcaactc aagatattgc catcatcgaa caacgtgcta aaatggatgg
     4741 acgtcaaatg ttcatgcaat tggcgccagc gactgacaaa aaataattgt cagaaagtta
     4801 aataaaggag aaaaaatcat gccaaaacaa aaaacacacc gcgcatcagc taaacgtttc
     4861 aaacgtacag gttctggtgg acttaaacgt ttccgtgctt acacttctca ccgtttccac
     4921 ggaaaaacta agaaacaacg tcgtcatctt cgtaaagcat ctatggtgca ttcaggagat
     4981 tacaaacgta tcaaagcaat gcttactcgc ttgaaataat agcttgactg taagtaaaca
     5041 attctagaaa atatttggag gaaataaaac atggcacgtg ttaaaggtgg cgttgtatca
     5101 cgcaaacgtc gtaaacgtat tcttaaatta gcaaaaggtt actatggagc taaacacatc
     5161 ttgttccgta ctgcaaaaga acaagtaatg aactcttact actatgcata ccgtgaccgt
     5221 cgtcagaaaa aacgtgactt ccgcaaattg tggattactc gtatcaatgc ggcggctcgt
     5281 atgaacggac tttcatactc acaattgatg catggtttga aattggctga gatcgaagtt
     5341 aaccgtaaaa tgcttgctga cttggctgtt aacgatgcag tagctttcac agctcttgca
     5401 gatgcagcta aagcaaaact tggtaaataa caactgatga gactggaaca ggattgtcca
     5461 gtctttttaa aaataaagga gaaagatatg gcttcaaaaa tgctacacac ttgcttacga
     5521 gtagaaaatc ttgaaaaatc aattgcattt tatcaagatg cttttggttt taaagaattg
     5581 cgtcgcagag attttccaga ccatgccttc acgattgtct atctaggtct tgagggtgat
     5641 gattatgagt tggagttgac ttataactac gatcacggtc cgtatgtggt tggtgatggg
     5701 tttgcccata tcgccctcag tacacctgat cttgaggcac ttcatcaaga acacagtgca
     5761 aaaggctatg aagtgactga gccaaatggt ctaccaggaa ctacaccaaa ctattacttt
     5821 gttaaagacc ctgatggata taaggtcgaa gtcattcgtg aaaaataatt tcgtgcaagt
     5881 taagtagaat attcgttttc tacttgactt tttttagctg aaagagtata ctaataaaaa
     5941 ttcaaccttt aaggggagtc cagagagact cacaaggtgt cagataaaag aatagtgcaa
     6001 ttttctagag gagacctttt gagtgtgctc tcttgtgttg tacgatttta actgaggcct
     6061 tgcactagca aggtcttttc tttatctggt ccccttaaaa tttaaggagg aaaagttatg
     6121 aatctcacat gtaagaagcg tttgggtgtc attcggttgg aaaccatgaa ggtggttgca
     6181 caagaggaaa tcgcgccagc aatctttgaa ttagtcctag aaggagaaat ggttgaagcc
     6241 atgcgagcag gccaatttct tcatctgcgt gtaccggacg atgcccatct cttacgtcgt
     6301 cctatttcaa tttcgtctat tgacaaggca aacaagcagt gtcacctcat ttatcggatt
     6361 gagggagctg ggactgcaat tttttcaacc ttaagtcagg gagacactct tgatgtgatg
     6421 gggcctcagg gaaatggttt tgacttgtct gaccttgatg agcagaatca ggttctcctt
     6481 gttggtggtg ggattggtgt tccacccttg cttgaggtgg ccaaggaatt gcatgaacgt
     6541 ggagtgaaag tagtgacagt cctcggtttt gctaataagg atgctgttat tttgaaaacg
     6601 gaattggctc agtatggtca ggtctttgta acgacagatg atggttctta tggcatcaag
     6661 ggaaatgttt ccgttgttat caatgattta gatagtcagt ttgatgctgt ttactcgtgt
     6721 ggggctccag gaatgatgaa gtatatcaat caaacctttg atgatcaccc aagagcctat
     6781 ttatctctgg aatctcgtat ggcttgtggg atgggagctt gctatgcctg tgttctaaaa
     6841 gtaccagaaa gcgagacggt cagccaacgc gtctgtgaag atggtcctgt tttccgcaca
     6901 ggaacagttg tattataagg agaaaattat gactacaaat cgattacaag tgtctctacc
     6961 tggtttggat ttgaaaaatc cgattattcc agcatcaggc tgttttggct ttggacaaga
     7021 gtatgccaag tactatgatt tagacctttt aggttctatt atgatcaagg cgacaaccct
     7081 tgaaccacgt tttgggaatc caactccaag agtggcagag acgcctgctg gtatgctcaa
     7141 tgcaattggc ttgcaaaatt ctggtttaga ggttgttttg gctgaaaagc taccttggct
     7201 ggaaagagaa tatccaaatc ttcctattat tgccaatgta gctggttttt caaaacaaga
     7261 gtatgcagct gtttctcatg ggatttccaa ggcaactaat gtaaaagcta tcgagctcaa
     7321 tatttcttgt cccaatgttg accactgtaa tcatggactt ttgattggtc aagatccaga
     7381 tttggcttat gatgtggtga aagcagctgt ggaagcctca gaagtgccag tttatgtcaa
     7441 attaaccccg agtgtgaccg atatcgttac tgtcgcaaaa gctgcagaag atgcgggagc
     7501 aagtggcttg accatgatca atactctggt tggaatgcgc tttgacctca aaaccagaaa
     7561 accaatcttg gccaatggaa caggtggaat gtcaggtcca gcagtctttc cagtagccct
     7621 caaactcatc cgccaagtag cccaaacaac agacctgcct atcattggaa tggggggagt
     7681 ggattcggct gaagctgccc tagaaatgta tctggctggg gcatctgcta tcggagttgg
     7741 aacagctaac tttaccaatc cttatgcctg tcctgacatc atcgaaaatt taccaaaagt
     7801 catggataaa tacggtatta gcagtctgga agaactccgt caggaagtaa aagagtctct
     7861 gaggtaaatt gcaatcaatc tgttcttgat tttttattag tttgtaatat gaatttagga
     7921 gaattttggt acaataaaat aaataagaac agaggaagaa ggttaatgaa gaaagtaaga
     7981 tttatttttt tagctctgct atttttctta gctagtccag agggtgcaat ggctagtgat
     8041 ggtacttggc aaggaaaaca gtatctgaaa gaagatggca gtcaagcagc gaatgagtgg
     8101 gtttttgata ctcattatca atcttggttc tatataaaag cagatgctaa ctatgctgaa
     8161 aatgaatggc taaagcaagg tgacgactat ttttacctca aatctggtgg ctatatggcc
     8221 aaatcagaat gggtagaaga caagggagcc ttttattatc ttgaccaaga tggaaagatg
     8281 aaacgaaatg cttgggtagg aacttcctat gttggtgcaa caggtgccaa agtaatagaa
     8341 gactgggtct atgattctca atacgatgct tggttttata tcaaagcaga tggacagcac
     8401 gcagagaaag aatggctcca aattaaaggg aaggactatt atttcaaatc cggtggttat
     8461 ctactgacaa gtcagtggat taatcaagct tatgtgaatg ctagtggtgc caaagtacag
     8521 caaggttggc tttttgacaa acaataccaa tcttggtttt acataaaaga aaatggaaac
     8581 tatgctgata aagaatggat tttcgagaat ggtcactatt attatctaaa atccggtggc
     8641 tacatggcag ccaatgaatg gatttgggat aaggaatctt ggttttacct caagtttgat
     8701 ggcaaaatgg ctgaaaaaga atgggtctac gattctcata gtcaagcctg gtactacttc
     8761 aaatccggtg gttacatgac agccaatgaa tggatttggg ataaggaatc ttggttttat
     8821 ctcaaatctg atgggaaaat agctgaaaaa gaatgggtct acgattctca tagtcaagct
     8881 tggtactact tcaaatccgg tggttacatg acagccaatg aatggatttg ggataaggaa
     8941 tcttggtttt acctcaagtc tgatggcaaa atggctgaaa aagaatgggt ctacgattct
     9001 catagtcaag cctggtacta cttcaaatct ggtggctaca tggcgaaaaa tgagacagta
     9061 gatggttatc agcttggaag cgatggtaaa tggcttggag gaaaagctac aaataaaaat
     9121 gctgcttact atcaagtagt gcctgtcaca gccaatgttt atgattcaga tggtgaaaag
     9181 ctttcctata tatcgcaagg tagtgtcgta tggctagata aggatagaaa aagtgatgac
     9241 aagcgcttgg ctattactat ttctggtttg tcaggctata tgaaaacaga agatttacaa
     9301 gcgctagatg ctagtaagga ctttatccct tattatgaga gtgatggcca ccgtttttat
     9361 cactatgtgg ctcagaatgc tagtatccca gtagcttctc atctttctga tatggaagta
     9421 ggcaagaaat attattcggc agatggcctg cattttgatg gttttaagct tgagaatccc
     9481 ttccttttca aagatttaac agaggctaca aactacagtg ctgaagaatt ggataaggta
     9541 tttagtttgc taaacattaa taatagcctt ttggagaaca agggcgctac ttttaaggaa
     9601 gccgaagaac attatcatat caatgccctt tatctccttg cccatagtgc cctagaaagt
     9661 aactggggaa gaagtaaaat tgccaaagat aagaataatt tctttggcat tacagcctat
     9721 gatacgaccc cttacctttc tgccaagaca tttgatgatg tggataaggg aattttaggt
     9781 gcaaccaagt ggattaagga aaattatatc gataggggaa gaactttcct tggaaacaag
     9841 gcttctggta tgaatgtgga atatgcttca gacccttatt ggggcgaaaa aattgctagt
     9901 gtgatgatga aaatcaatga gaagctaggt ggcaaagatt agtactataa gtgaatatga
     9961 tttgagtgaa tagtaagtta aaaatcctga tttcaagtaa aatcaggatt ttttcatgga
    10021 tgcaattttt ttggagtctg gtgtgacgcg gagggtcttt tgtcctgtgt aagtgacaaa
    10081 gccgggtttt ccaccagttg gtttattgag ttttttgact tcaatcatat ctacctgcac
    10141 cagattcgac aggcgccctt gagagaagta ggcagctaac tctgctgcgt ctgtcttgac
    10201 tgcatcagat gggtcaagat ttcctgagat gacaacatgg cttccaggaa tgtccttagc
    10261 atggaaccaa agttcctcct tgcgggccat tttaaaggtc aattcctcat tttgaagatt
    10321 gtttcgtccg acatagatga tggttttgcc atcgcttgct agatattgtt ctagtttttt
    10381 gcgtttctgg attttctccc gttgtcttct gcggataaaa cctgtttgaa tcaattcttc
    10441 acggatttca gcgatttctt ccagtccagc ttggttgagg acggtttcta cactttccag
    10501 atagagaata gtggctttgg tttcttcaat caaatcagtc aagtatttga cagcttcttt
    10561 gagtttctga taccgtttaa aatagcgttg ggcattctgg ttgggagtca gagccttatc
    10621 aagcgcaatc atgataggtt ggttggtata gtagttgtct aggataacct ggtcttggtc
    10681 gttaggcact tggtgtagga aggttgtcag caattctcct ttttgacgaa attcttcagc
    10741 gttgtctgtc gccagtaact ctttttcctg ttttttgagt ttgtgtcggt ttttctgaag
    10801 ttcattttca acacgacgaa tcagttcact ggcctgctgt ttgacgcggt cgcgctcagc
    10861 cttatcctta tagtaggtgt ccaacaaatc agaaagattt gcaaaaggct ctcccacctg
    10921 atttgcaaaa ggaactggac tgaaggaagt ctcagtcaag catggcttgg tttcttgatt
    10981 gaaaaaattt cggaaagcgg aaagtttttc actaaccagt atcctttcca attcatttgc
    11041 agtatcgcgt cccagacctt gaaagaggct ttgaagattt tttgctgtta gttcttgggt
    11101 ttgcaggatt tcaaagagct tttcatcttt gatagtaaaa ggattgagag attctgtact
    11161 tggcggagcg atataggtca atcctggaag taaggtgcgg tagctatttt gtgaaaaacc
    11221 gacgtgtttg ataacttcga ggattttatg actgctttta tcgaccagta gaatattact
    11281 gtgtttcccc ataatttcaa taatcaaggt agcctggata tggtctccaa tctcgttttt
    11341 attggaaact gtaatttcca caatacggtc attttccact tgctcaatcg actcaatcag
    11401 ggccccctgc aaatactttc tcaaaaccat gataaaggta gaaggttgag ctggattttc
    11461 aaaagtcgtt tgggtcagct gaatgcgtcc aaaaactgga tgggcagaaa ggagcaggcg
    11521 atggctttgg cgattgctgc ggatttgcaa gaccaactct tgttcaaaag gctgattgat
    11581 tttctggatg cgaccattca ctaattcgct tcgcaattcc tcaactatgt ggtgtaaaaa
    11641 aaatccatca aatgacatcg ttctctcctt gtgattgtat tccatagtat tatatcaaaa
    11701 aggtagaata aaatcataga aatgtggtat aataaagcca agtaaagaga aacgagaagc
    11761 acatgtatat tgaaatggta gatgaaactg gtcaagtttc aaaagaaatg ttgcaacaaa
    11821 cccaagaaat tttggaattt gcagcccaaa aattaggaaa agaagacaag gagatggcag
    11881 tcacttttgt gaccaatgag cgtagtcatg aacttaatct ggagtaccgt gacaccgacc
    11941 gtccgacaga tgtcatcagc cttgagtata aaccagaatt ggaaattgcc tttgacgaag
    12001 aggatttgct tgaaaatcca gaattggcag agatgatgtc tgagtttgat gcctatattg
    12061 gggaattgtt catctctatc gataaggctc atgagcaggc cgaagaatat ggtcacagct
    12121 ttgagcgtga gatgggcttc ttggcagtac acggcttttt acatattaac ggctatgatc
    12181 actacactcc ggaagaagaa gcggagatgt tcggtttaca agaagaaatt ttgacagcct
    12241 atggactcac aagacaataa acgaaaatgg aaaaatcgtg acctgatatc cagtttagaa
    12301 tttgccatca cagggatttt tactgctatc aaggaagaac gaaatatgcg aaaacatgca
    12361 gtgacggctc tagtggtcat ccttgcaggt tttgtttttc aggtgtcacg aatcgaatgg
    12421 ctctttctcc tattgagcat tttcttggta gtagcctttg agattatcaa ctctgctatt
    12481 gaaaatatgg tggatttggc cagtcactat cacttttcca tgctggctaa aaatgccaag
    12541 gatatggcgg ctggcgcggt attagtggtt tctcttttcg cagtcttaac aggtgcattg
    12601 atttttctcc cacgaatctg ggatttatta ttttaaacag taagaggaaa ttatgacttt
    12661 taaatcaggc tttgtagcca ttttaggacg tcccaatgtt gggaagtcaa cctttttaaa
    12721 tcacgttatg gggcaaaaga ttgccatcat gagtgacaag gcgcagacaa cgcgcaataa
    12781 aatcatggga atttacacga ctgataagga gcaaattgtc tttatcgaca caccagggat
    12841 tcacaaacct aaaacagctc tcggagattt catggttgag tctgcctaca gtacccttcg
    12901 cgaagtggac accgttcttt tcatggtgcc tgctgatgaa gcgcgtggta agggggacga
    12961 tatgattatc gagcgtctca aggctgccaa ggttcctgtg attttggtgg tgaataaaat
    13021 cgataaggtc catccagacc agctcttgtc tcagattgat gacttccgta atcaaatgga
    13081 ctttaaggaa attgttccaa tatcagccct tcagggaaat aacgtgtctc gtctagtgga
    13141 tattttgagt gaaaatctgg atgaaggttt ccaatatttc ccgtctgatc aaatcacaga
    13201 ccatccagaa cgtttcttag tttcagaaat ggttcgcgag aaagtcttgc acctaactcg
    13261 tgaagagatt ccgcattctg tagcagtagt tgttgactct atgaaacgag acgaagagac
    13321 agacaaggtt cacatccgtg caaccatcat ggtcgagcgc gatagccaaa aagggattat
    13381 catcggtaaa ggtggcgcta tgc
//
LOCUS       DAVHTH010000051        13364 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.051, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000051 DAVHTH010000000
VERSION     DAVHTH010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13364)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13364)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13364
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.051"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            243..365
                     /locus_tag="VVR63_001624"
     CDS             243..365
                     /locus_tag="VVR63_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000196333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent transferase"
                     /protein_id="HEU6129623.1"
                     /translation="MTRDFKFETLQLHAGQVVTPATKSRAVPIYQTTSFVFDDT"
     gene            387..1502
                     /locus_tag="VVR63_001625"
     CDS             387..1502
                     /locus_tag="VVR63_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001231001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase"
                     /protein_id="HEU6129624.1"
                     /translation="MRKPGNIYTRITNPTTAALEGGVEALATASGMTAVTYTILALAH
                     AGDHVVAASTIYGGTFNLLKEPLPRYGITTTFVDVDNLEEVEAAIKDNTKLVLIETLG
                     NPLINIPDLEKLAEIAHKHQIPLVSDNTFAIPYLINVFSHGVDIAIHSATKFIGGHGT
                     TIGGIIVDSGRFDWMASGKFPQFVDEGSSCHNLSYTRDVGAVAFIIAVRVQLLRDTGA
                     ALSPFNAFLLLQRLETLSLRVERHVQNAETIVDFLVNHPKVEKVNYPKLADSPYYALA
                     EKYLPKGVGSIFTFHVKGDEEEARKVIDNLEIFSDLANAADAKSLVVHPATITHGQLS
                     EKDLEAAGVTPNQIHLSIGLENVEDLIEDLRLALEKI"
     gene            1598..2872
                     /locus_tag="VVR63_001626"
     CDS             1598..2872
                     /locus_tag="VVR63_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HEU6129625.1"
                     /translation="MNEIKCPNCGEVFTVNESQYAELLSQVRTAEFDKELHDRMRQEL
                     ALAEQKAMNEQQTKLAQKDQEIAQLQSQIQNFDTEKELAKKEVEQTSHQALLAKDKEV
                     QALENQLATLRLEHENQLQKTLSDLEKERNQVKNQLLLQEKENELSLASVKQNYEAQL
                     KAASEQVEFYKNFKAQQSTKAIGESLEQYAESEFNKVRSFAFPNAYFEKDNKVSSRGS
                     KGDFIFRECDENGVEIISIMFEMKNEADGTEKKHKNADFYKELDKDRREKNCEYAVLV
                     TMLEADNDYFNTGIVDVSHEYEKMYVVRPQFFIQLIGLLRNAALNSLKYKQELALVRE
                     QNIDIMHFEEDLDAFKLAFAKNYNSASTNFGKAIDEIDKAIKRMEEVKKFLTTSENQL
                     RLANNKLEDVSVKKLTRKNPTMKAKFEALKGE"
     gene            2882..3760
                     /gene="truB"
                     /locus_tag="VVR63_001627"
     CDS             2882..3760
                     /gene="truB"
                     /locus_tag="VVR63_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HEU6129626.1"
                     /translation="MNGIINLKKEAGMTSHDAVFKLRKILGTKKIGHGGTLDPDVVGV
                     LPIAVGKATRMVEFMQDEGKIYEGEIILGYSTTTEDASGEVVAKTPVLSSLDEKLVDE
                     AIASLTGPITQIPPMYSAVKVNGRKLYEYARAGQEVERPERQVTIYQFERTSPISYDG
                     QLARFTFRVKCSKGTYIRTLSVDLGEKLGYAAHMSHLTRTSAAGLQLEDALTLEEIAE
                     KVEAGQLDFLHPLEIGTGDLVKVFLTPEDATEVRFGRFIELDQTDKELAAFEDDKLLA
                     ILEKRGNLYKPRKVFS"
     gene            4001..4303
                     /locus_tag="VVR63_001628"
     CDS             4001..4303
                     /locus_tag="VVR63_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEU6129627.1"
                     /translation="MMRNEFRERVEQLLQQKEINENSELSHLFRLAIQNLDRNEKYQT
                     VMANLSQGLSLYLMTHHYQAPKSVIDFGLWIAKAPSQERGRLAFLQMLAQTLQGFR"
     gene            4411..5049
                     /gene="udk"
                     /locus_tag="VVR63_001629"
     CDS             4411..5049
                     /gene="udk"
                     /locus_tag="VVR63_001629"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HEU6129628.1"
                     /translation="MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYK
                     DQSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQ
                     EPQDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQ
                     YLGVVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK"
     gene            5177..6517
                     /locus_tag="VVR63_001630"
     CDS             5177..6517
                     /locus_tag="VVR63_001630"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HEU6129629.1"
                     /translation="MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRPTHQY
                     FSLKDDHAVIQATIWSGIYQKLGFDLEEGMKINVIGRVQVYEPSGSYSIIIEKAEPDG
                     VGALAIQFEQLKKKLTEEGLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRF
                     PGVNILLYPTKVQGEGAAEEIARNIARANQRDDLDLLIIGRGGGSIEDLWAFNEEIVV
                     RAIFESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLTHLQNQEK
                     RMATAVRNVLSKKQEALKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDN
                     KQLVQARTHQLVQLSPVTKIQRYQDRLGQLDKLLGSQMALVYDAKVAEAKRLSEALLM
                     LDTSRIVARGYAIVKKEESIVDSVESLKKKDQVTLLMRDGQVELEVKDVKTKEI"
     gene            6495..6707
                     /locus_tag="VVR63_001631"
     CDS             6495..6707
                     /locus_tag="VVR63_001631"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HEU6129630.1"
                     /translation="MSKQKKFEENLAELETIVQSLENGEIALEDAITAFQKGMVLSKE
                     LQATLDKAEKTLVKVMQEDGTESDFE"
     gene            6704..7579
                     /locus_tag="VVR63_001632"
     CDS             6704..7579
                     /locus_tag="VVR63_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HEU6129631.1"
                     /translation="MKKQEKLALVESALEDFYGDQQFASSLRESVLYSIHAGGKRIRP
                     FLLLEVLEALQVTIKPAHAQVATALEMIHTGSLIHDDLPAMDDDDYRRGRLTNHKKFG
                     EAMAILAGDALFLDPYALIAQADLPSQIKVDLIANLSLASGSLGMVAGQVLDMEGEHQ
                     HLSLEELQIIHANKTGKLLAYPFQAAAIIAELSPEMQVKLKTVGELIGLAFQVRDDVL
                     DVTASFEEIGKTPQKDLQAEKSTYPALLGLEESIAFCNQTLDQANEKLEEIAQQLPFE
                     TESIVSVVESLRING"
     gene            7572..8387
                     /locus_tag="VVR63_001633"
     CDS             7572..8387
                     /locus_tag="VVR63_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HEU6129632.1"
                     /translation="MAKERVDVLAYKQGLFETREQAKRGVMAGLVVAVLNGERFDKPG
                     EKIPDDTELKLKGEKLKYVSRGGLKLEKALQVFDLSVDGATTIDIGASTGGFTDVMLQ
                     NSAKLVFAVDVGTNQLAWKLRQDPRVVSMEQFNFRYAEKTDFEQEPSFASIDVSFISL
                     SLILPALHRVLADQGQVVALVKPQFEAGREQIGKNGIIRDAKIHQNVLESVTAMAVEA
                     GFSVLGLDFSPIQGGHGNIEFLAYLKKEKSASNQIFAEIKEAVERAHSQFKNE"
     gene            8380..8811
                     /locus_tag="VVR63_001634"
     CDS             8380..8811
                     /locus_tag="VVR63_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEU6129633.1"
                     /translation="MNKKERLEKIRRLVTDYQIGTQEEIVEHLKEAGITATQATVSRD
                     IKELGIVKIPLRDNTYVYELPKSIVKSLQLAEDNIESAELMDKMINLQVIPGNTAFVK
                     AQLIETFADKIFSCLTDDSSILVIARSGSLAEEIFEQVKNW"
     gene            8818..10485
                     /gene="recN"
                     /locus_tag="VVR63_001635"
     CDS             8818..10485
                     /gene="recN"
                     /locus_tag="VVR63_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HEU6129634.1"
                     /translation="MLLEISIKNFAIIEAISLNFEKGMTVLTGETGAGKSIIIDAMNM
                     MLGARATTDVIRHGAPKAEIEGLFSVENSRLLQEIFDEQGLELGDEIIIRREILQNGR
                     SISRVNGQMVNLSVLRTIGQHLVDIHGQHDHEELMRPQLHIQMLDEFGDAAFWDLKET
                     YQTSFDAYRKMRKQVLEVKKNQQEHKARIEMLEFQMAEIEAANLQAGEDLALNQERDK
                     LLNHKNIADTLTNAYSMLDNEDFSSLANVRSAMNDMESVEEYDPEYREISSSLSETYY
                     VLEDISKRLEAIIEDLDFDGNRLMQVENRLDLLHTITRKYGGTVDDVLLYFAKITEEY
                     NLLTGNNLSSEDMEAELKKLEVNLVNLAGQLASARHNLAQQLEAEIKQELQDLYMEKA
                     QFQVRFSKGKFSREGNEMVEFYISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRKE
                     GKTSIVFDEVDTGVSGRVAQAIAQKIHKIGQHGQVLAISHLPQVIAIADYQFFIEKIS
                     NDHSTVSTVRLLTVEERVEEVAKMLAGDDVTEAALTQARELLRNREK"
     gene            10487..11215
                     /locus_tag="VVR63_001636"
     CDS             10487..11215
                     /locus_tag="VVR63_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HEU6129635.1"
                     /translation="MTDYYVIGDVHGKAGMLEDLLKTWDGQTQLLFLGDLIDRGEDSH
                     RVLEMVKDLVDNQGAICLSGNHEYMFLTWLDDPEESYDHYRRNGGDTTINSILGRPLD
                     APVDGVEDAKRVAAEASDLVEFIRQMPFVVETDKYIFVHAGIDLTLDDWHETTDYKKV
                     WLRKPFHGAENHTGKTIVFGHTPVYGLLQQERGTSELWTTEDGKIGMDGGAVYGGVLH
                     GIVFTDQGMTEHHFIENDGFVAED"
     gene            11294..13117
                     /gene="lepA"
                     /locus_tag="VVR63_001637"
     CDS             11294..13117
                     /gene="lepA"
                     /locus_tag="VVR63_001637"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HEU6129636.1"
                     /translation="MNLEELKKRQGKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNDLEIMPIINKIDLPAADPERVRTEIEDVI
                     GLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVTAPLKALIFDSVYDAYRGVILQ
                     VRVMDGVVKPGDKIQLMSNSKTFDVAEVGIFTPKAVGRDFLATGDVGYIAASIKTVQD
                     TRVGDTVTLATNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNLTDGESMD
                     VSNPSEFPDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYQIPLAEIVFDFFDKLKSSTRGYASFDYELSEYRPSKLVKMDILLNGDKVDALSFI
                     VHKDFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKSIGSVEVPQEAFLSVLSMDEE"
BASE COUNT         3983 a         2452 c         3187 g         3742 t
ORIGIN      
        1 gtgtgacttt catcggaaac tttatcggag gaggcctctt gatgggtctt ccatatgcct
       61 tcctcaataa aaacgaagat acttatgtag attaagaaaa tgagcacgat tgagtcgtgc
      121 ttttttcatt ttcaaaataa gataatagct atttcttata tcaaaatata gaaaactgat
      181 atttgtaaac tataactcaa ggtgctacaa tatccttaat aaaataatat ggaggtcacc
      241 ttatgactcg tgattttaaa tttgaaactc tacaactaca tgctggtcaa gttgtgactc
      301 cagctactaa gtctcgtgca gtgccgattt atcaaacaac atcttttgtt tttgatgaca
      361 cgtaggaagg tgccgatctg tttgccttga ggaaaccagg gaacatttat actcgtatca
      421 ccaatcctac aacagctgcc cttgaaggtg gtgttgaagc gctagcaaca gcatcaggta
      481 tgactgcagt gacttatacg attttggcgc ttgcccatgc tggtgaccat gtagtggctg
      541 cttcgactat ttacggtgga accttcaatc ttttgaaaga accccttcct cgttatggta
      601 tcacaacaac ctttgtcgat gttgataatt tggaggaagt agaagcagct atcaaagaca
      661 ataccaagct tgtcttgatt gaaaccttgg gtaacccctt gattaatatt ccagacctgg
      721 aaaaactggc agagattgct cataaacatc aaatcccact tgtgtcagac aatacttttg
      781 caatacctta tttgattaac gtcttctctc atggcgttga cattgccatt cactctgcga
      841 ctaagtttat cggtgggcat ggtacaacta ttggaggaat aattgtcgat agtggtcgtt
      901 ttgactggat ggcttcaggg aaattccctc aatttgttga cgagggttca agctgccaca
      961 atttgagcta tactcgtgat gtgggtgcag tagcctttat tatagctgtt cgagttcaat
     1021 tgcttcgtga tacaggtgca gccttgtcac cattcaatgc tttcctcttg ctacaaagac
     1081 ttgaaaccct ttcacttcgt gtggaacgcc atgtacaaaa tgctgagaca attgttgatt
     1141 ttcttgtcaa ccatcctaag gtagaaaagg taaattatcc aaaacttgca gatagtcctt
     1201 attatgcctt ggctgagaaa tacttgccaa aaggtgtcgg ttcaatcttt accttccacg
     1261 tcaaaggtga cgaggaggaa gcacgcaagg tcattgataa tttagaaatc ttttctgacc
     1321 ttgcaaacgc ggcagatgct aaatcgcttg ttgtccatcc agcaacaatc actcacggtc
     1381 aattgtcaga aaaagaccta gaagcagcag gtgtcacacc aaatcaaatc cacttgtcta
     1441 tcggtcttga aaatgtagaa gatttgattg aagacttacg cttggccttg gaaaaaattt
     1501 aaagtaaaag aagataaaca gtgggttttg actcactgtt tttgattttc cctcaggcat
     1561 gatataatgg ttacagaagt ctagaaagag gaatgtaatg aacgaaatca aatgtcccaa
     1621 ctgtggggaa gtctttacag taaatgaaag ccagtatgct gaacttttgt cccaagtgag
     1681 aacggcagag tttgataagg aactacacga taggatgagg caggaactgg ccttggctga
     1741 gcaaaaggct atgaatgagc aacagactaa actggctcag aaggatcaag aaattgcgca
     1801 attgcagagt caaatccaaa actttgatac agaaaaagaa ttggccaaga aagaagttga
     1861 acagacaagc catcaggcct tattggctaa ggacaaggaa gtacaggcct tggaaaacca
     1921 gttggcgacc ttgcgtttgg agcatgaaaa tcaattgcaa aagacccttt ctgacctaga
     1981 aaaagaacgc aatcaggtca aaaatcagct cctactgcaa gaaaaggaaa atgagttgtc
     2041 tttggcttct gttaagcaaa actacgaagc ccagctcaaa gcagccagtg aacaagtcga
     2101 gttttataag aattttaagg ctcaacaatc tacaaaagcg attggggaaa gcctagaaca
     2161 gtatgcagag agtgagttta acaaggttcg tagtttcgcc tttccaaatg cttactttga
     2221 gaaggataac aaggtctctt cgcgtgggtc taaaggggac tttatcttcc gtgagtgtga
     2281 tgaaaatgga gttgaaatca tttctatcat gtttgagatg aaaaacgaag cggacggaac
     2341 agagaagaag cacaagaatg cagattttta caaggaattg gacaaggacc gtcgggagaa
     2401 gaactgtgag tatgccgttt tggtgaccat gcttgaggct gataatgact actttaacac
     2461 agggattgtt gacgtcagtc acgagtatga aaaaatgtat gttgttcgtc ctcaattctt
     2521 tatccaattg attggtctct tacgtaatgc ggcgctaaat tccctaaaat acaagcagga
     2581 gttggccttg gttcgcgagc aaaatattga cattatgcat tttgaggaag acttggatgc
     2641 ctttaagcta gcttttgcta agaactataa ttcagcttcg actaactttg gaaaagctat
     2701 tgatgaaatc gacaaggcca tcaaacgcat ggaagaggtt aagaaattcc tgactacatc
     2761 tgaaaaccaa ctccgtctag ctaacaacaa attggaagat gtctctgtta aaaaattgac
     2821 ccggaaaaat ccaacaatga aagcgaagtt cgaagcactg aagggggagt agaaagcaaa
     2881 aatgaacggt attatcaact taaaaaaaga agcaggaatg acctcgcatg atgcggtttt
     2941 taaactgcgt aagattttgg gaaccaagaa aattggtcat ggtggaacct tggatccgga
     3001 tgtggtgggt gttttgccga ttgcggttgg caaggcgaca cgcatggtcg agtttatgca
     3061 ggacgagggt aagatctatg agggggaaat cattctgggc tattccacga cgactgagga
     3121 tgctagtggg gaagtggtcg caaaaacccc tgttttgtct tcattggatg aaaagcttgt
     3181 tgatgaagcg attgctagct tgactgggcc tattacccag attcccccta tgtattcggc
     3241 agttaaggtt aatggtcgca agctctatga gtatgcgcgt gctggtcagg aagtggagcg
     3301 tccagaacgt caggtgacca tttatcaatt tgagcgaaca agtccgattt cttatgatgg
     3361 ccaacttgcc cgattcactt ttcgtgtaaa atgcagtaaa gggacttaca tccgtacttt
     3421 gtcagttgat ttgggtgaaa agcttggtta tgcggctcat atgtcccatt tgactcgtac
     3481 tagtgctgct ggcttacaat tagaagatgc tcttaccttg gaggaaattg ctgaaaaagt
     3541 agaggctggg caattagatt ttctccatcc tttagagatt gggacaggtg accttgtcaa
     3601 agttttccta actccagaag atgctacaga agttcgcttt ggtcgtttta ttgagctaga
     3661 ccaaacggac aaagaactgg ctgcctttga agatgataaa ttgttagcca ttctagaaaa
     3721 acggggcaat ctctataagc caaggaaggt ttttagctag atcgtttagg aataaaaatc
     3781 gggtgataga taacaattgc ttgataaaac cccatactaa tagtagaatg gttttgggaa
     3841 ttataatatt ccaattgttg cgagttgtag atactcaaat aatctatata gaaatttaga
     3901 ggtgtgaaat gaagcaactt aaaattcttt cagataaata tttagagtcc attacaggtt
     3961 ctggtgggaa cttaggccca ggatttggtg tgataattcc atgatgcgaa atgagtttcg
     4021 agaaagggtg gagcaacttc ttcaacaaaa agaaataaat gaaaatagtg agttgagtca
     4081 cctgtttcgt cttgctatac aaaatttaga cagaaatgaa aaataccaaa cggtcatggc
     4141 caatttgagt caagggttgt cactttacct catgacgcat cattaccagg cacctaagtc
     4201 tgtcattgat tttggtttat ggattgccaa agctcctagc caggaaagag ggagactggc
     4261 tttcttgcag atgcttgctc aaaccctaca gggctttcgt taaaactgtc gaacatcaga
     4321 gggaagactc tggtgttttt tgctgatgag actataaatt ttgtaaaaaa tgtgatagaa
     4381 tagacgacgg ataaaataac ggaggatagc atgcaaaata gaccaatcat tattggagtg
     4441 acaggtggtt ctggtggtgg taaaaccagt gtttcaagag ccattttatc gcattttcct
     4501 gatgaaaaga tttccatgat tgagcatgat tcatactaca aggatcagtc tcatttgacc
     4561 tttgaagagc gtgtcaaaac caactatgac catccttttg cctttgatac agacttgatg
     4621 atcgagcaga ttaaggaatt gttggcaggg cgtccggtgg acatcccgac ctacgactat
     4681 acagagcata cacggagtag caagacctat cgtcaggagc ctcaagatgt ctttatcgtt
     4741 gagggcattt tggtcttgga ggacaagcgt ctgcgcgatt tgatggatat caagattttt
     4801 gtggatacgg atgacgatgt gcgcattatt cgtcgtatca agcgtgatat ggaggagcgt
     4861 ggccgtagcc ttgatagcgt tattaaccag tacttaggtg tggtcaaacc aatgtaccac
     4921 cagtttatcg agtcaactaa gcgttatgct gatatcgtca ttcctgaagg ggttagcaat
     4981 accgtggcta tcgacctgtt gacgaccaag attgcaaaga ttttggaaga agctcgaaac
     5041 agcaaataat cacatgtgga ggccttgcct cctttttcta tttttccctc ataatggtac
     5101 ataaatggag atttttaggc atatttttgg tataataata cccatgaaag agcaagtaaa
     5161 tgaatagtag gtggagatgg aaaagtattt atcggtaaca actttgacca agtatctgaa
     5221 aatgaaattc gataaagacc catacttgga acgggtctat ttaactggtc aagtttccaa
     5281 ctttcgtaaa cgacctactc accaatattt ctccctaaag gatgaccatg cagttattca
     5341 agcgaccatc tggtctggga tttatcagaa attagggttt gacctggaag aaggaatgaa
     5401 gatcaatgtg attgggcgtg tacaggtcta tgaaccaagt ggtagctact ccatcatcat
     5461 tgaaaaagct gagcctgatg gggttggggc gcttgcgatt cagtttgaac aacttaagaa
     5521 aaaattgaca gaagaaggcc tgtttcaaga acgcttcaag caagctctac cccaattttc
     5581 taagagaatt ggggtagtaa ccagccgtag tggagccgtt attcgagata ttatcacgac
     5641 cgtcagcagg cgattcccag gtgttaacat ccttctttat cctaccaagg ttcaaggtga
     5701 aggggctgcg gaggaaattg ctagaaatat tgcgcgtgct aatcaacggg acgatttgga
     5761 tttgctcatt attggtcgtg gaggtggttc tattgaggat ctctgggcct ttaacgaaga
     5821 aattgtggta cgagctattt ttgaatctcg tttgccagtt atctctagtg tggggcatga
     5881 gacggatgtg accttggcag attttgtggc agatcgacgc gctgcaacgc caacagcggc
     5941 ggctgaactg gcaacacctg tgaccaagtt ggatgtatta actcatttgc aaaatcagga
     6001 aaaacggatg gcaacggcag tccgaaatgt tctatctaag aaacaagagg ctttgaaaaa
     6061 atgcagtcag tctgttatct ttagacaacc tgagcgcttg tatgacggtt atttgcaacg
     6121 cttggaccaa ctgcaactgc gtttgaaaca aagtttgcga actcggattt ctgataacaa
     6181 acaattagtt caagcaagaa ctcatcaatt agtacaatta tcacctgtta ccaaaatcca
     6241 acgctatcaa gaccgtttag gacagttgga caagctctta ggtagccaaa tggcgttagt
     6301 ttatgacgcc aaggttgctg aggccaagcg actttcggaa gctttgctca tgttggatac
     6361 tagccgaatc gtggcgcgtg gttatgctat tgtcaaaaaa gaagagtcca ttgtagattc
     6421 ggttgagagt ttgaagaaaa aagaccaagt aacgcttttg atgcgagatg gtcaagtaga
     6481 attagaggtt aaagatgtca aaacaaaaga aatttgagga aaatctagca gaactggaaa
     6541 ccattgtcca aagtttggaa aatggtgaaa ttgctctgga agatgcgatt actgcctttc
     6601 aaaagggcat ggtcttgtca aaagagctcc aagctacgct ggacaaggct gaaaagacct
     6661 tggtcaaggt catgcaagaa gacggaacag aaagtgattt tgaatgaaaa agcaagaaaa
     6721 attagctctt gtcgagtcgg ctttggaaga tttttatgga gaccagcagt ttgcctctag
     6781 tttacgggag tctgttctct attctattca tgctggtggc aagcgtattc ggccttttct
     6841 cttgttagaa gttctggaag ccttgcaggt taccatcaaa cctgctcacg cgcaggtagc
     6901 tactgccttg gagatgattc atacagggag cttgattcac gatgaccttc ctgctatgga
     6961 tgatgacgat tatcgaagag ggcggttaac caatcacaag aaattcggtg aagctatggc
     7021 cattttggct ggagatgcct tattcttaga cccatatgcc ttgattgcgc aggcagattt
     7081 gccaagtcag attaaggtgg acttgattgc caacttatcc cttgcttcag gtagtctggg
     7141 tatggtggca gggcaagttt tggatatgga gggcgaacac cagcacttgt ctttggaaga
     7201 acttcagatt attcatgcca ataagactgg gaagttacta gcctatccct tccaagcggc
     7261 agctattata gctgaattgt cacctgaaat gcaggtgaag ctgaaaactg tgggtgaatt
     7321 gattggactt gcttttcaag tcagagatga tgtactggat gtgacagcta gttttgagga
     7381 aatcggcaag acacctcaaa aggatctgca ggcagaaaaa tcaacctatc ctgccctgtt
     7441 gggcttggaa gagtccattg ccttttgtaa ccaaaccctg gatcaagcta atgaaaaatt
     7501 agaagaaatt gcccagcagc ttccctttga aacagaatcg attgtaagtg tagtagaaag
     7561 tttgagaatc aatggctaag gaaagagtgg atgtactagc ttataaacag gggttgtttg
     7621 aaacgagaga gcaggccaag cgaggtgtaa tggctggcct agtcgtagca gtccttaatg
     7681 gagaacggtt tgacaagcca ggagagaaaa ttccagatga caccgaatta aaactcaagg
     7741 gagagaaact caagtatgtc agccgtggtg gtttgaaact ggaaaaggcc ttgcaggtct
     7801 ttgatttgtc ggtggatggc gcgactacga ttgatatcgg ggcctctact ggaggtttta
     7861 ccgatgtcat gctacagaat agtgccaagt tggtctttgc agtcgatgtt ggtaccaatc
     7921 agttggcttg gaaattacgc caagacccac gagttgttag catggagcag ttcaatttcc
     7981 gctatgctga aaagactgat ttcgagcagg agccgagctt tgccagtatt gatgtgagtt
     8041 tcatttccct tagtctgatt ttgccagcct tgcatcgtgt cttggctgat caaggtcagg
     8101 tggtagcact tgtcaaacct cagtttgagg caggacgtga gcagattggg aaaaatggaa
     8161 ttattcgaga tgctaagatt catcagaatg tccttgaatc tgtaacagct atggcagtag
     8221 aggcaggttt ttcagtcctt ggcttggact tttctcccat ccaaggtgga catggaaata
     8281 ttgaattttt agcgtatttg aaaaaagaaa agtcagcaag caatcagatt tttgctgaga
     8341 ttaaagaagc agtagagagg gcgcatagtc aatttaaaaa tgaataaaaa agagagactt
     8401 gaaaaaatta gaagattggt gacagattat caaatcggca cgcaagaaga aattgtagaa
     8461 catttgaaag aagcaggtat cactgccact caggcgacgg tatcccgaga tatcaaagag
     8521 ttaggtattg tcaaaattcc tttgagagac aacacctatg tctacgaatt accaaaatca
     8581 atcgtaaaaa gtctgcaact ggctgaagac aatatcgaat cggctgaatt gatggataag
     8641 atgatcaatc tccaagttat tccaggaaat acggcttttg taaaagctca gttaatcgag
     8701 acttttgcag acaagatttt tagctgtttg actgatgata gctcgatttt agtcattgcc
     8761 agaagtggaa gtctagcaga ggaaatcttt gaacaagtaa aaaattggta ggtctatatg
     8821 ttacttgaaa tttcgataaa aaactttgcc attattgagg ctatttccct caattttgaa
     8881 aaggggatga ctgtcctgac tggtgaaacg ggtgcaggga agtcgattat cattgatgcc
     8941 atgaatatga tgttgggagc tcgtgcgacg acagatgtta ttcgtcatgg tgcaccaaag
     9001 gcagagattg aagggctttt ctcagttgag aatagtcgtc ttttacagga aatttttgat
     9061 gagcaaggtt tagaattagg tgatgaaatt atcatccgtc gggaaatctt gcaaaatggt
     9121 cgtagtatca gccgtgtaaa tggtcagatg gttaatctgt ctgttttgcg aactattggg
     9181 caacatcttg tagatattca tggtcagcat gaccatgagg agttaatgcg tccccaactg
     9241 catatccaga tgttggatga atttggtgat gccgcttttt gggacttgaa agaaacctat
     9301 caaacgagtt ttgatgccta tcggaaaatg cgcaagcagg ttctggaagt caagaaaaac
     9361 caacaggaac acaaggcacg tatcgaaatg ttggaatttc aaatggcaga gattgaggca
     9421 gcaaacttgc aggctggaga agacttggct ctcaatcaag agcgagataa actcctcaac
     9481 cacaaaaata ttgcggatac actgaccaat gcctacagta tgttggacaa tgaagatttt
     9541 tcaagtctgg ccaatgttcg ttcagccatg aatgacatgg aaagtgtcga agagtatgac
     9601 cctgaatacc gtgaaatttc aagctctctg tctgagacct actatgtttt agaagacatt
     9661 agcaaacgtt tggaagctat cattgaggac cttgattttg atggcaatcg cctcatgcag
     9721 gttgagaatc gtttggacct ccttcatact attactcgta agtatggtgg gactgttgat
     9781 gatgttttgc tttattttgc caagattacg gaagaataca atctcttgac aggcaataat
     9841 ctttcgtctg aggacatgga agcagagctt aagaagttgg aagtcaatct tgtcaatttg
     9901 gcaggtcaac ttgcttctgc tcgtcataat ttggctcagc aactcgaagc tgagattaaa
     9961 caagaactgc aagatcttta tatggaaaaa gcccagtttc aggttcgttt tagtaaggga
    10021 aaattcagtc gtgagggaaa tgaaatggtt gagttttata tttcaaccaa ccctggagaa
    10081 gactttaaac ccttggttaa ggttgcttct ggaggggaat tatctcgtct catgttagcc
    10141 attaagtctg ccttttcacg taaagaaggc aagactagca ttgtctttga tgaagtggat
    10201 acgggagttt caggtcgtgt tgctcaagct attgctcaga aaattcataa aattggtcag
    10261 catggtcagg ttttggctat ctcccatttg ccacaagtaa ttgcgattgc agattatcaa
    10321 ttctttattg agaagattag taatgaccat tcaacggttt cgactgttcg tctcttgacg
    10381 gtcgaagagc gagtggagga agttgccaag atgttggcag gtgatgatgt gacagaagca
    10441 gccctgacgc aagccagaga attgttgaga aacagggaga aataagatga cagattatta
    10501 tgtaattgga gatgttcacg gaaaagctgg gatgctggaa gaccttctca aaacctggga
    10561 tggtcagacc cagttgctct ttctaggtga tttgattgac agaggtgagg atagtcaccg
    10621 tgttcttgaa atggtcaagg acttggtgga caatcaaggg gctatctgtt tgtctggaaa
    10681 ccacgagtat atgtttttga cttggctaga tgacccagaa gaaagttatg accattatcg
    10741 tcgcaatggt ggagatacaa ccattaactc tatcctaggt cgtcccttgg atgcaccagt
    10801 tgatggagta gaagatgcca agcgggttgc cgctgaagcg tcagacttgg tcgaattcat
    10861 tcgtcaaatg ccatttgtag tagagacaga caagtatata tttgttcacg caggtattga
    10921 tttgaccttg gacgactggc atgaaacaac agattataaa aaagtatggc ttagaaaacc
    10981 attccacgga gctgaaaatc atactggaaa aaccattgtc ttcggtcata caccggtcta
    11041 tggtttgtta cagcaagaac gcggtacatc tgagctttgg actacagaag atggcaagat
    11101 tggaatggat ggaggagctg tttatggtgg tgtccttcac gggattgtct ttacagacca
    11161 aggaatgaca gaacaccact ttatcgaaaa tgacggcttt gtcgctgaag attagtactc
    11221 ctagcagggt atggtcttgt caaaatatca aaaacaattt ataataaata gataccctga
    11281 aaggaagaga atcatgaact tagaagaatt gaaaaaacga caggggaaga tccgtaactt
    11341 ctctattatc gcccatattg accacgggaa atcaactcta gcagaccgca ttttggaaaa
    11401 aacagagacg gtttcaagtc gtgaaatgca ggcccagctt ttggatagca tggatctaga
    11461 gcgggaacgt ggaattacta ttaagttgaa tgccatcgag ttgaattaca ctgcaaaaga
    11521 tggggaaact tatattttcc acttgattga cacaccaggg cacgttgact ttacctatga
    11581 agtttcacgt tcgctagctg cctgtgaggg tgctattttg gtggtcgatg cggctcaagg
    11641 aattgaggct caaactcttg ccaacgttta tctggctttg gataatgatt tggaaatcat
    11701 gcctatcatt aataaaattg acctgccggc tgcagatccg gagcgcgtgc gtacagagat
    11761 tgaagatgtg attggtttgg atgccagtga agcagttttg gcttctgcca aggctgggat
    11821 tgggattgaa gaaatcctcg agcaaattgt agaaaaagta ccagcaccaa cgggtgatgt
    11881 gacggcgcca cttaaggcct tgattttcga ctctgtttac gatgcttacc gtggggttat
    11941 cctccaagtg cgtgtcatgg acggagtggt caaacctggt gataagattc agctcatgag
    12001 caatagtaag acctttgatg tggccgaagt cggtattttt acaccaaaag cggttggtcg
    12061 tgatttcctt gcgactggtg atgttggtta cattgcggcg tctatcaaga cggttcagga
    12121 tactcgtgtg ggtgataccg ttaccttggc aaccaatcct gcggcagaac cattacatgg
    12181 ttataagcag atgaatccta tggtctttgc gggtctctac ccaatcgaat caaacaaata
    12241 caatgacctg cgtgaagcgc ttgaaaaatt gcaactgaat gatgctagtc ttcagtttga
    12301 accagaaaca tctcaggcac ttggatttgg tttccgttgt ggatttcttg gacttctcca
    12361 tatggatgtt atccaggaac gtttagagcg tgagttcaat attgacctca tcatgacagc
    12421 tccgtctgtt atttacaaag ttaatttgac cgacggtgag tctatggatg tgtctaaccc
    12481 atctgagttt ccagacccaa ctaagattgc gaccattgaa gagccttatg tcaaggcgca
    12541 aatcatggta ccacaggagt tcgtcggagc agtaatggag ctagctcagc gtaagcgtgg
    12601 ggactttgtg actatggact atattgatga taaccgtgtc aatgttatct atcaaattcc
    12661 tcttgctgaa attgtctttg acttctttga taaacttaag tcttcgacac gtggttatgc
    12721 aagctttgac tacgaattgt cagaatatcg cccatctaag ctggtgaaaa tggatatcct
    12781 tctcaatgga gataaggtgg atgccctcag ctttatcgtt cacaaggact ttgcctacga
    12841 acgtgggaaa ctcatcgttg ataaactcaa gaaaatcatc cctcgccaac aatttgaagt
    12901 tccaatccaa gcggctattg gacacaagat tgtcgctcgt actgatatca aggcccttcg
    12961 taagaacgta cttgctaaat gttatggtgg tgacgtttct cgtaagcgta aactccttga
    13021 aaaacaaaaa gctggtaaga aacgcatgaa atccatcgga tcagttgaag ttccgcaaga
    13081 agccttcctc agcgtcttga gtatggatga agaataagtt atcagaaatg cctttccttg
    13141 ttcacaggaa atttatataa gaatcaatag taaagcaggc ttagatggtc tgctttttta
    13201 gtttttatac tcttcgaaaa tctcttcaaa ccacgtcagc gtcgccttac tgtatgtatg
    13261 gttactgact tcgtcagttt catctacaac ctcaaaattg tgttttgagt aacctgcggc
    13321 tagcttccta gtttgctctt tgattttcat tgagtattag aaca
//
LOCUS       DAVHTH010000052        12642 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.052, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000052 DAVHTH010000000
VERSION     DAVHTH010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12642)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12642)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12642
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.052"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            <1..924
                     /locus_tag="VVR63_001638"
     CDS             <1..924
                     /locus_tag="VVR63_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000116042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6129637.1"
                     /translation="WLDIEEDLPKSTDVDIKYGLPNHIKGNIDEATLFLCLVNPNIDE
                     VKTEKKDVGIHTYYKKAREMESGDDSLNILNDKGKLRIDPKVYIKEHILDVRETSSIL
                     YNELQIVKQTRSYKDTYYLGHYLPHFIKEFLNKKGSFKNVIHNLTDEWDELEKMSKKI
                     ANLEAFPFRSQNPNYTYKSNKRATNFTNLLIESDSKVNLLSARVIIWRIVKHLESSQH
                     KPAFILRRFNTFWLPTISKVLEQDLNFTKEEINQIINALDEEYFFTVRKKDYNGQSGY
                     FGRNFCKNNERISNSSFKHLVQETLGEYVKK"
     gene            1009..1959
                     /locus_tag="VVR63_001639"
     CDS             1009..1959
                     /locus_tag="VVR63_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WYL domain-containing protein"
                     /protein_id="HEU6129638.1"
                     /translation="MKPQERLLTIFFRLQAGERLSKAQLSDEYEIDYRTVQRYMSTLK
                     NFLQEQRISNTEIKFDTSDNTYRLIAKTTFNKKDILVISKILLENRALNKSELYSLLE
                     DLLSLLSSEEQKEIDAIIGSERFNYKSLTNDKDRIDTIWILSEAIRREQMLEIEYKAP
                     LKDIKSHIIFPVSLYYDAHYFYLVAYHLKHENYTTYRVDRMESLSESHVKKPEISYGR
                     KYRDGEVRNQKVDAFEGRKIDVTLIYKGNTEIVLDQFPEREILSENHDEIKVKIKTQD
                     TPGLKRWILGQGDAVTLLSPSKLIEEIQESLENTLRNYKK"
     gene            2031..2417
                     /locus_tag="VVR63_001640"
     CDS             2031..2417
                     /locus_tag="VVR63_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6129639.1"
                     /translation="MYKCEIREDFETAWLENIMEVIEFHGRYVTGDMISLTLSDLRHL
                     AEGKFLAWNVEDVYSQVLYLDEDAKEMLLSVESHLYNFQEISQKIMSGRLTRQNYYLL
                     GKLIDEFHAVKAAMRVIETKRNDFNI"
     gene            2539..6543
                     /locus_tag="VVR63_001641"
     CDS             2539..6543
                     /locus_tag="VVR63_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000209102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UvrD-helicase domain-containing protein"
                     /protein_id="HEU6129640.1"
                     /translation="MTTLDFKTLFKEEYDKLNKQQKKAVDTVEGPVMVIAGPGTGKTQ
                     ILSRRVANILTNYHTSSEEIVCLTYTEAGASEMLDRLEKLIGEEGRKVRVSTIHAFCS
                     ELILRNSEIFGGQPKIISTAAKYEILKEIMDEYVIEGNPLYKNSGKRYSAKDQLLELF
                     YKMKRENLNKEDFEKEIDEYFKMIDLSIPGDDLYSKFKYARNSKSKDKKVGDYKDKAI
                     NELKENTQKLLAGVEIIEKYSSDISNHNYFDFDDMILWTIEKLEENEGFQRSVSDTIR
                     YLFVDEFQDTSVVQNKLVDLLVKGKDNPNIFVVGDDDQSIYRFQGVSANNIRDFDKKY
                     KPTKIVLDENYRSSQAIIDASRQLISHNPREEKLLIAAGANKDYDYQLPILKSYENAK
                     AEMFGVLTEIKELIDSGVSPNEIGVIYGRNSYGEEFAKILRDKGIFVQMKENKDLFSE
                     PFFKKIVAILKYLCKPSRDVRELRKIVYFDFFEVVLSQIVMIRNLKKDEKISIPTIAE
                     IDQKLEIIRKKVNQSSKYLSPMYVLSDVLKSLSIDEYIMKSKEKYHLVSVLNELYKLM
                     LMECHIHPKLTVKGFLNQLSALEEMGISLPIEDISGSPSNCVQLMTAHGSKGLEFDHV
                     FIMKCNDGKKKSEAWPGGENNSGRFSYPPSLNGKDENESQLKEEENRRLFYVAMTRAK
                     KVLHLSYANDSTKTHLINEFEEFIDEVDVTESFEDCQSVDKVVMPKFSNNVINEIFDE
                     LSLSVSTLNSFLKCPLSFYFNKGLKLPSETNEAMVFGSIIHEVLEKIYISVDGSQSSE
                     LTAKTVLSLEEALKLFETVFEEKSYQLTSNKIKKDDYARGKKIIENLYKKSGYLKDGV
                     VAVEVPIQGIRLGDILNTTVDLSEVSNIEINGKIDKIECDGNIVCLVDYKTGNFENAK
                     KKLVAPSEKEPLGGDYWRQAVFYYILFKNAGIDISDKEILVKYVLVENSTNEDGFSET
                     EDIRITQKEVDIVLNQIKESIMKIKQGDFNCGCGVLKKDRDNYPCDYCLQVSANTTPK
                     FDNTEALEVATYQQTRGNYKSLSVSKLNRYLRCPKSIYFEDVLQLSQAAGLSAGAKEK
                     STKITINHAPTGPVFGTAIHETMEKIYKEDLQLEDAIEFYDSSLYSHQEEIIDTMSVE
                     ELKEYGHNLLTNLFEHFIPNSLKGEHVSLEKELRVKLGDNYSINGIIDKLEFDNDLIR
                     VVDYKTGSAQRGVEELEVGHDYWRQAVFYNLLLENSSEIDTTDKRIETQYIFLDDNST
                     ESGYSIHTIQVTKEDLDLVTSQIQNFWSHMNTADFTGSCGKNDCDYCRLAEFVDFELL
                     KETIESGKESNLVN"
     gene            6609..6863
                     /locus_tag="VVR63_001642"
     CDS             6609..6863
                     /locus_tag="VVR63_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000456893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6129641.1"
                     /translation="MEYVEAVNQFIERHYKEKDIGHIEIDFWGNKNHPHSLYIYKRSK
                     KIEYDYFFFDSIDYYEEPDFLEFKYIVHLENITYIFWQED"
     gene            7247..7603
                     /locus_tag="VVR63_001643"
     CDS             7247..7603
                     /locus_tag="VVR63_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6129642.1"
                     /translation="MKRDIRSIRKQFRLTETEEKQILDLMREKGEDNFSDFLRKSLLL
                     SDGQKQMEKWFNLWKKQKLEQISRDVHEILIIAKINHQVTQEHVSILLTCIQELIKEV
                     EKTSPLSENFRNKYMR"
     gene            7608..7973
                     /gene="mobC"
                     /locus_tag="VVR63_001644"
     CDS             7608..7973
                     /gene="mobC"
                     /locus_tag="VVR63_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000401240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HEU6129643.1"
                     /translation="MEHRYRTNLKKVFLSDLELVKLNENISKSNCLSFSEYARRTLLD
                     PGMNFITIDTNSYQDLIFELKRIGNNINQIARSINYSNLITEVELNELRKGIEELIVE
                     VEKDFLIQSEKLRKFYGHH"
     gene            7960..9789
                     /locus_tag="VVR63_001645"
     CDS             7960..9789
                     /locus_tag="VVR63_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HEU6129644.1"
                     /translation="MVITKHFAIHGKNYRSKLVKYILNPSKTKNLALVSDFGMRNYLD
                     FPSYKELVKMYNDNFLSNDGLYEFRHDRQEVNQRRIYSHHIIQSFSPDDHLTPEQINR
                     IGYETVKELTGGRFRFIVATHVDKGHIHNHIILNSIDQNSDKKFLWNYKSERNLRMVS
                     DRLSKIAGAKIIENRYSHRQYEVYRKTNYKYEIKQRVYFLIENSKNFEDFRKKAKALH
                     LIIDFRHKHVTFFMTDSNMKQVVRDDKLNRKQPYNETYFKQKFVQREIINILEFLLPK
                     MKNMNELIQQAEFFDLKIIPKEKHVLFEFNGIKLSEQELGKMNQYSVSYFQDYFNNKN
                     ETFVLDNNNLIELYNKEKLIKEKELPTEEVVWKSYQDFKRNRDAVHELEVELNLNQIE
                     AVVDDGIYIKVQFGIRQEGLIFVPNIQINMEEEKVKVFLRETSSYYVYHKDSADKNRF
                     MKGKTLIRQFTLQHEPQHMYRRIPLSKIKEKIEQLDFLISAENSPNDFEDITNDFIAQ
                     ISYLENMIEQVQNKIDDLTNLEEVLLNNTTNSSSNLENSIQGKSSVDTIEKDLYIYKG
                     KIETLKEQHGEAINLFEMFNKTIKKYKKKQNMKSIEENEIHLE"
     gene            9893..10117
                     /locus_tag="VVR63_001646"
     CDS             9893..10117
                     /locus_tag="VVR63_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU6129645.1"
                     /translation="MLKRIRDLREDDDLTQEYIAKIVLNCTRSSYSKMEAGSRLISIN
                     DLIKLADFYKVSLDYLVGRVDNKEDHYSKK"
     gene            10390..10659
                     /locus_tag="VVR63_001647"
     CDS             10390..10659
                     /locus_tag="VVR63_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 family protein"
                     /protein_id="HEU6129646.1"
                     /translation="METVNYKDLVAIGFPEHTSRNIIRQAKKIAVKKFEEARKNDKNA
                     VQLGCSPFDNKRLGIAPKNIVENLIGISFSDIEGEKNGYIKDKEI"
     gene            10631..11818
                     /locus_tag="VVR63_001648"
     CDS             10631..11818
                     /locus_tag="VVR63_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEU6129647.1"
                     /translation="MVISKTKKYKGVYKDSKGKIYFQIELGVDPITGKRIQKKGRKNQ
                     QGLPFNSFKEAYEEILRLKHEFVNSTINNSFLTFREFMEEIYLKYYQQKVQFVTYQTA
                     LPHHQLFIKQFGSKKLSDISTIDCERFRLAIIDKYSSNYAKNMWSRFKACLGYAERLG
                     YIDRVPFKGLDNPRGKHPDTKFWTFDEFKKIINSFDISEYEGLHNYMTIWLYFMTGLR
                     VSEGIALKWEDIDFERKWIHVHSTIEKDKNGVWYAKQQTKTVAGNRKIDLDDFTITIL
                     KKWREVQIKNDDKDYVISRFGAPLCKSTISRIIKRHAKITGVPEITGKGLRHSHASYL
                     INVLHKDTLYVSYRLGHADKSTTLNTYSHWYYSGDSTISEEITNSLDNLGLSIYLPNS
                     CQS"
     gene            12071..12241
                     /locus_tag="VVR63_001649"
     CDS             12071..12241
                     /locus_tag="VVR63_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001168336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6129648.1"
                     /translation="MQKEGQSSRQFVKSHLMTIMGVDIVKATQLVDEMEQVGLIRFDE
                     FGNVGILVLEGQ"
     gene            12241..12489
                     /locus_tag="VVR63_001650"
                     /pseudo
     CDS             12241..12489
                     /locus_tag="VVR63_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648301.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
BASE COUNT         4819 a         1600 c         2293 g         3930 t
ORIGIN      
        1 tggttagata ttgaggaaga tttacctaaa agtacagatg ttgatatcaa gtatggatta
       61 cctaatcaca taaaaggaaa tattgatgaa gcaacattat ttttatgttt agtgaatcca
      121 aatattgatg aagtaaaaac cgagaagaag gatgttggaa ttcacacata ttataaaaaa
      181 gcaagagaaa tggagagtgg agacgactca ttaaacatct taaatgataa aggcaaattg
      241 agaatagatc ctaaagtata tatcaaagaa catatcttgg atgtaagaga aacgagcagt
      301 attttataca atgaattaca aattgtaaaa caaactcgct cttataaaga tacttactat
      361 ctaggacatt acttgccaca ctttataaaa gaatttttaa ataaaaaagg ctcttttaag
      421 aatgttattc acaatttgac tgatgagtgg gatgagttag aaaaaatgtc aaaaaaaata
      481 gctaatttag aggctttccc atttagaagc caaaatccaa attacactta taaaagtaat
      541 aaaagagcaa caaactttac aaatctactg attgaatcag atagtaaagt taatttgtta
      601 agtgcaagag tgattatttg gagaatcgtt aagcatttag agtcatctca acataaaccc
      661 gcctttatat tgagaaggtt taatactttt tggttaccta ctatatctaa agttttagaa
      721 caagacttga attttacaaa agaagaaata aatcaaatca taaacgcact agatgaagaa
      781 tactttttta ctgttaggaa aaaagattat aacggtcaat caggatattt tgggcgaaat
      841 ttttgtaaaa ataatgaaag aattagtaat agtagtttta aacacttagt tcaggaaacc
      901 ttaggggaat atgtgaaaaa ataaagtgaa gttgtattta tgttatcagc tttagaaaat
      961 aaagatttca ataaattatt ttaaattaat agaattgatt ggtaagatat gaaaccacaa
     1021 gaacgacttt taacaatctt tttccgttta caagcaggcg agaggctatc aaaagctcaa
     1081 ttaagcgatg aatatgagat tgattatagg actgtacaaa gatatatgag cacattaaaa
     1141 aattttttgc aagagcagcg tatatcaaat acagagataa aattcgatac ttcagataat
     1201 acctatcgtt tgattgctaa aacaactttt aataaaaagg atattttagt aatttcaaaa
     1261 attcttttgg agaatcgtgc actaaacaaa tcagaactat attcattact cgaagatctt
     1321 ctatctttac tctcaagcga agaacaaaaa gagatagatg caattattgg cagtgagcgt
     1381 tttaactata aatcactgac taatgacaag gacaggattg atacaatttg gattttgtcg
     1441 gaagctattc gtagggagca aatgctcgaa atagaatata aagctccgtt aaaagatatc
     1501 aaaagccaca tcatttttcc tgtttccctc tattatgatg cccactattt ttatctagtt
     1561 gcttaccatt tgaaacatga aaattataca acgtatcgtg ttgataggat ggagagtctg
     1621 agtgaatctc atgtaaagaa accagaaatt tcatatgggc gtaagtaccg agatggggag
     1681 gttcgaaatc aaaaagtaga tgcttttgaa ggaagaaaaa ttgatgttac tttaatctat
     1741 aaaggaaata ctgaaattgt tttagatcag tttccagagc gtgaaattct ttctgagaat
     1801 cacgatgaaa taaaagtaaa aattaaaact caagacacac caggtctcaa acgatggatt
     1861 ctaggacaag gtgatgcagt cactctttta tcaccttcaa agttgattga agaaatacaa
     1921 gaatctcttg aaaacacatt aagaaattat aaaaaatgaa gaggtagaca aaaaatgtct
     1981 acctcttcat ttataataga gatacagatg aggaaagaag gtaacagtag atgtataaat
     2041 gtgaaataag agaagatttt gaaacagcat ggttagaaaa tataatggaa gtaatagagt
     2101 ttcatgggag gtatgttaca ggtgatatga tttcgctaac tttatctgat ctaagacact
     2161 tagcagaggg gaaatttctt gcttggaatg tagaggatgt gtattcacaa gtactatatc
     2221 ttgatgaaga tgctaaggaa atgttattaa gtgtagagag tcatttatat aatttccaag
     2281 aaatttccca aaaaataatg tcaggaagat taactcgaca aaactactat cttcttggaa
     2341 agttgattga tgaatttcat gcagttaaag cggcaatgag agttattgaa acaaaacgta
     2401 atgattttaa tatttagatt ttcttatctt atagattcta aaatacttaa gtaagtattt
     2461 aacaccatat gtgaaaacgc ttttaaatat ggtataatta acacaaaaga agtacttata
     2521 gttaagcgag gtaaaacgat gacaacatta gattttaaaa ctttatttaa agaagaatat
     2581 gataaactta ataaacaaca gaaaaaagca gttgatacgg tggaaggacc tgttatggtt
     2641 attgctggtc ctggaacagg taaaactcaa attctgtcac gtcgtgtcgc aaatatttta
     2701 acaaattatc atacaagttc agaagaaatt gtctgtttaa catatacaga ggctggtgca
     2761 tcagaaatgt tggatagatt agaaaaatta attggagaag aagggcgtaa ggtaagagta
     2821 tcaactatcc atgctttttg tagtgaatta atcttaagaa actctgaaat tttcggtgga
     2881 caaccaaaaa ttatctcaac agcagccaaa tatgaaatcc taaaagaaat tatggatgaa
     2941 tatgttatag aaggaaatcc tctttataaa aactctggta aacgttattc tgctaaagac
     3001 cagctattag aactttttta taaaatgaaa cgcgaaaacc tgaacaaaga ggattttgaa
     3061 aaagagatag atgaatactt taaaatgatt gatttatcca tacctggaga tgatttgtat
     3121 agtaaattca aatatgctag aaattctaag tctaaagaca agaaagttgg agattataaa
     3181 gataaggcta taaacgaatt aaaagaaaat actcaaaagt tacttgctgg agttgaaatt
     3241 attgaaaagt atagctctga tattagcaat cacaattatt ttgactttga tgatatgatt
     3301 ttatggacaa ttgaaaagtt ggaggaaaat gaaggttttc aaagaagtgt atctgatact
     3361 ataagatatt tatttgttga tgagtttcag gatacttcag ttgttcagaa taaacttgta
     3421 gatttactag taaaaggaaa agacaatcca aatatttttg ttgtagggga tgatgatcaa
     3481 agtatttatc gtttccaagg agtaagtgcg aataatattc gagattttga taagaagtat
     3541 aaacctacga aaatagtact tgatgaaaat taccgttctt cccaagctat cattgacgct
     3601 tcaagacaac taatcagtca taatccaaga gaagagaaac ttcttattgc agcaggcgct
     3661 aacaaagatt atgactatca attgccaatc ttgaaatcct acgaaaatgc aaaagctgaa
     3721 atgtttggtg tgcttactga gattaaagag ctgattgatt cgggtgtttc tcctaatgaa
     3781 ataggagtca tttatggaag aaattcttac ggagaagagt ttgcgaagat tcttcgtgat
     3841 aaaggtattt tcgttcaaat gaaagaaaat aaagatttat ttagtgaacc tttcttcaaa
     3901 aaaattgtag ctattttaaa atatctttgt aaaccatcaa gagatgttag agaacttcga
     3961 aaaattgtat attttgattt ctttgaggta gtactatcac aaatcgtaat gatacggaat
     4021 ctaaagaaag atgaaaaaat ttcaatcccc actatagcag aaattgatca aaaattagaa
     4081 atcattcgaa aaaaagtaaa tcaatcatca aaatacctat cgcctatgta tgtccttagc
     4141 gatgtattaa aatctttaag tatcgatgag tatattatga agtcaaaaga gaaatatcat
     4201 ttggtttctg ttttaaatga actttacaag ttaatgttga tggaatgcca catccatcct
     4261 aaattgactg taaaaggatt tttaaatcaa ttatcagctt tagaagaaat gggaattagt
     4321 ctaccaattg aagatatctc aggttctcca agtaactgcg ttcaattaat gacagctcat
     4381 ggttccaaag gactcgagtt tgatcatgtg tttataatga aatgcaatga tggaaagaaa
     4441 aagagtgaag cttggccagg aggtgaaaat aattcaggta gattctctta tccaccaagt
     4501 ttaaatggaa aagatgaaaa tgaatctcaa ctaaaagaag aggagaaccg tcgcttgttt
     4561 tatgttgcta tgactcgggc aaagaaggtg ctccatctct cttatgctaa tgattctact
     4621 aaaacccact taattaatga atttgaggaa tttattgatg aggtagacgt gacagaatct
     4681 tttgaggatt gtcaatctgt agataaagtg gtaatgccga aattttctaa caatgttatc
     4741 aatgaaattt ttgacgaatt gagtttaagc gttagtacat taaattcttt tcttaaatgt
     4801 cctttgagtt tttatttcaa taagggatta aaattaccat ctgaaacaaa cgaagctatg
     4861 gtattcggta gcattattca cgaagtctta gaaaaaatat atatttctgt agatggttca
     4921 caaagttcag aattaactgc aaaaacagta ctttctctag aagaagcttt aaaattattt
     4981 gagacagtct ttgaagaaaa atcttatcaa ttgacttcaa ataaaataaa gaaagatgac
     5041 tatgctagag ggaaaaagat tattgaaaat ctttacaaga aatctggata cctcaaagat
     5101 ggtgtagttg cagttgaggt acctattcaa ggtattcgac taggcgatat tttaaatacc
     5161 accgtagacc tatcggaagt atctaatatc gagataaacg gaaaaattga taaaattgag
     5221 tgcgacggca atatagtgtg tctagtcgac tataaaacag gaaattttga aaatgctaaa
     5281 aagaaattag tagctccgag tgaaaaagaa ccccttggtg gtgattattg gcgtcaggct
     5341 gtattctatt atatcctctt caaaaatgcc ggtatcgata tttctgacaa agaaatactt
     5401 gttaaatatg ttttggttga gaattcaact aatgaagatg gtttttctga aactgaagat
     5461 atacgaatca ctcaaaaaga agttgatata gtgcttaatc agattaaaga atctattatg
     5521 aaaattaaac aaggcgattt taactgtggt tgtggagtat tgaaaaagga cagagataat
     5581 tacccatgcg actactgtct ccaagtatca gctaacacaa cacctaaatt tgataatact
     5641 gaagccttag aagttgcgac ttatcaacaa acacggggaa actataagag tttaagcgtt
     5701 agcaaattga atcgttacct gcgttgtccg aagagtatct actttgaaga tgttttacag
     5761 ttatctcaag cagctggatt atcagcagga gcaaaagaaa aatctacaaa aataacaatc
     5821 aatcatgccc ccacaggtcc cgtatttggg actgcaattc atgaaacaat ggaaaaaatc
     5881 tataaagaag atttacaatt agaggacgca attgaattct atgatagttc attgtactct
     5941 catcaagagg aaatcattga tacaatgtct gtagaagaat taaaagaata tggacataac
     6001 ttgttgacta atctttttga acattttatt cctaatagtt taaaagggga gcatgtttcc
     6061 ttagaaaaag aacttcgtgt taaattagga gataattact caatcaatgg gattatcgat
     6121 aagcttgaat ttgataatga tcttattcga gttgtagatt ataagacagg ttctgctcaa
     6181 agaggtgttg aggaactaga agttggacat gattattggc gtcaagcagt cttctataat
     6241 cttttattag aaaattcttc tgaaatagat acgactgata aacgaattga aactcagtat
     6301 atttttcttg atgataatag tactgaaagt ggctattcaa ttcacactat acaagttacg
     6361 aaagaggatt tagacttagt tacatcacaa attcaaaact tctggtctca tatgaataca
     6421 gctgatttta ctggtagttg tggtaaaaac gattgtgatt attgtcgatt agctgagttt
     6481 gttgattttg aattattaaa agaaactata gaatccggaa aagaaagtaa tttagttaat
     6541 taagtggttt aattcatttg ctagtataga acgataagtt aagtttccta gtaattacga
     6601 ggtaaataat ggaatatgtt gaggctgtta atcaatttat agagagacat tataaagaga
     6661 aggatattgg tcatatagag atagattttt ggggtaacaa aaatcatcct catagcttgt
     6721 acatatacaa acgttctaaa aaaattgagt atgattattt tttctttgat tctattgatt
     6781 attatgaaga gccagatttt ttagagttta agtatatcgt tcatttagaa aatattacgt
     6841 atatattttg gcaggaagat taggcattat ataaaataac aatatctaaa atcaacatca
     6901 gttattaact ctataatatt cgtaatggtg aaaactaata tgaatattat ggagtttttt
     6961 tgtgataact tctccaagtt ttttacgcta tacttttctc aacttactaa aaatctatat
     7021 tagattttct ctggggggtg ggggcgtgcc accacatttt catatcgttt gcttttttat
     7081 ccgtgggggt tgaaattgca tgcgatatga tttttgggat attgtggaca caatatctga
     7141 gctcgcaaag ccttacaaaa atgttgaatc tattttgaaa aacgtactga cagtgtctgt
     7201 aagcttacat tgtcagtaca agtttctatg agggaggaaa agccatatga aaagagatat
     7261 acgtagtatt cggaaacaat ttcgcttaac agaaacggaa gaaaaacaaa tactagattt
     7321 aatgagagag aaaggagagg ataatttttc tgattttctc cgtaaaagct tactattgtc
     7381 tgatggacaa aaacagatgg aaaaatggtt caacctttgg aaaaaacaaa agttggaaca
     7441 aattagccgt gatgttcatg aaatattaat aattgctaaa ataaatcatc aggtgactca
     7501 agaacatgtt tctattttgt taacttgtat tcaggaatta attaaagagg tagaaaaaac
     7561 aagtcctctt agtgaaaatt ttcgtaacaa atacatgagg tagtagagtg gagcaccgat
     7621 atagaacaaa tttaaaaaaa gtctttttat ctgacctaga attagtcaaa ttgaatgaaa
     7681 atatctcaaa aagtaactgc ttatcattct cagaatatgc tagacgaact ctactagatc
     7741 ctggtatgaa ttttatcacc attgatacaa atagttatca agatttgatt tttgaattaa
     7801 aacgaatcgg aaataatatt aatcaaatag ccagaagcat aaattattcg aatttaataa
     7861 cggaggttga attaaatgag ttgagaaaag gtatagaaga gttaatagta gaagtggaga
     7921 aagattttct tattcaatct gaaaaattga ggaaatttta tggtcatcac taaacacttt
     7981 gcgattcatg gaaaaaatta tcgtagcaaa ctagtcaaat atattttgaa tccaagtaaa
     8041 acaaaaaatc tagcactagt ttcagatttt ggtatgagaa attatttaga ttttcctagt
     8101 tataaagaac tagtgaagat gtacaatgat aattttttaa gtaatgatgg tctttatgaa
     8161 tttcgtcatg ataggcaaga agtaaatcaa cgaagaattt attctcatca tattattcag
     8221 tctttttctc cagatgatca tcttactcct gaacaaatca atcggattgg ttatgagaca
     8281 gttaaagagt tgacaggagg tagatttcgt tttatcgtag caacacatgt cgataaaggt
     8341 catatccaca atcacatcat cctaaattca attgatcaga attctgataa aaagtttcta
     8401 tggaattata agtcagaacg taatctacga atggtttcag atcgtctctc aaaaattgca
     8461 ggtgcaaaga ttatagaaaa tcgttattcg catcgtcagt atgaagttta tcgaaaaacc
     8521 aattacaaat atgaaataaa acaacgggta tattttctaa ttgagaactc gaaaaatttt
     8581 gaagatttca ggaaaaaagc aaaagcttta catttaataa ttgattttag acacaagcat
     8641 gttacttttt ttatgactga ttcaaatatg aaacaagtcg tacgtgatga taaattgaat
     8701 agaaaacaac cttataatga aacttatttt aagcaaaagt ttgttcaaag ggaaattata
     8761 aacatcttag aatttctact tccgaaaatg aagaatatga atgaattgat tcaacaagca
     8821 gaattttttg acttaaaaat aattccgaaa gaaaaacatg ttctatttga atttaatggg
     8881 attaagcttt cagaacagga attgggaaaa atgaatcagt acagtgttag ttattttcaa
     8941 gactatttta ataacaaaaa tgaaactttt gtcttagata ataataattt aattgaactt
     9001 tacaataaag aaaagctaat taaagaaaaa gagttgccga cagaagaggt ggtatggaaa
     9061 tcctatcaag atttcaagag aaatagggat gctgttcatg agttagaagt agagttgaat
     9121 cttaatcaaa tagaagcagt agtagacgat ggaatttaca ttaaggtaca gtttggtatc
     9181 cgacaagaag gacttatttt tgtaccaaat attcaaatca atatggaaga agaaaaagtt
     9241 aaagtatttc tcagagaaac tagttcttac tatgtatatc ataaagattc agcagacaaa
     9301 aatcgcttta tgaaaggtaa aactttaatt aggcaattta cgcttcagca tgaaccgcag
     9361 catatgtata gaagaatacc tcttagcaaa attaaagaaa aaatagaaca attagatttt
     9421 cttatatctg cggaaaatag tccgaatgat tttgaagata taacaaatga tttcattgcc
     9481 caaatatcat atctagagaa tatgattgaa caagtccaaa ataaaattga tgatttaact
     9541 aatttagagg aagtattgtt gaataatacg acaaatagtt ctagcaattt agaaaatagt
     9601 attcaaggta aaagttcagt agatacgata gagaaggatt tatacatata taaaggaaag
     9661 attgaaacac tgaaggaaca acatggagaa gcaataaatt tatttgaaat gtttaataaa
     9721 acaataaaga aatataagaa aaaacaaaat atgaaatcta ttgaggaaaa tgagatacat
     9781 ttagagtaaa cagtttccta aaaagtatat atagaatagt ttcatgtgcc aatttgtcac
     9841 atatttaaaa ataagaaaat aactatatta tacttgtttt aggagacaac aaatgttgaa
     9901 aaggattaga gatttacgag aagatgatga tttgacacaa gaatatattg cgaaaatcgt
     9961 tttgaattgt acaagatcat cttattctaa aatggaagct ggtagcaggc taatctctat
    10021 aaatgacctt atcaaacttg cagattttta taaggtgagt ctagactacc ttgtaggtcg
    10081 agtggataat aaagaagacc attactccaa aaagtagtag gttaagaaag cacattgaca
    10141 attgaatagt ccaaaatggt actttcctca tttgtggagc agttttgaat ggctcgccat
    10201 gataagagcg acattaaaac catcaataaa atagagcgat actttatatg ccatgataca
    10261 aatgatatac aatgatactt ctgaccgttc aggctgccac cgtaaaagag cagcaagtgt
    10321 aattcttatg atgacttcat cagtcatgcc atggaggtga aaaaatctaa gaaaggaagt
    10381 agtaaaatca tggaaacagt aaactataaa gatttagttg cgattggttt tccagagcac
    10441 acatcgagaa atattattag acaagcaaaa aagattgctg taaaaaagtt tgaagaagct
    10501 agaaaaaatg ataagaatgc ggtacaatta ggatgttcac ctttcgataa taaaaggtta
    10561 ggcattgctc ctaaaaatat tgtagaaaat ttaattggta tttctttttc agatatagaa
    10621 ggtgagaaaa atggttatat caaagacaaa gaaatataaa ggtgtataca aagattcaaa
    10681 aggaaaaatt tattttcaaa ttgaattagg agttgatcca ataactggga aaagaattca
    10741 aaagaaagga aggaaaaatc aacagggact accgtttaat tcttttaagg aagcatatga
    10801 agagatactt cgtttaaaac atgaatttgt gaactctact attaataata gttttttaac
    10861 ttttagagag tttatggaag agatttattt aaaatattat caacaaaaag ttcaatttgt
    10921 aacttatcag accgctttac cacatcatca gttatttatt aagcaatttg gtagtaaaaa
    10981 attatcagat attagtacta ttgactgtga aagatttcgc ttagctatta tagacaagta
    11041 ttctagtaac tacgctaaaa atatgtggtc tagatttaaa gcatgtctgg gctatgcaga
    11101 aagattgggt tatattgata gagttccttt taaaggatta gataatccta gaggaaagca
    11161 ccctgataca aaattttgga catttgatga atttaagaag ataataaact cttttgatat
    11221 tagtgagtat gagggactcc ataattacat gacgatctgg ttatatttta tgactggctt
    11281 aagagttagt gagggtattg cacttaaatg ggaagatatt gattttgaac gtaaatggat
    11341 tcatgttcat tcgacaattg agaaagacaa aaacggtgta tggtatgcta aacaacaaac
    11401 aaagacagta gcagggaatc gtaaaattga tttagatgat tttacgatta caatacttaa
    11461 aaaatggcga gaagttcaaa tcaagaatga tgataaagat tatgtaatat cacgttttgg
    11521 tgcccctttg tgtaagtcta caatttctag gataataaag aggcatgcta agattactgg
    11581 tgtaccagaa attacgggga aaggattaag acatagtcat gcatcttatc ttataaatgt
    11641 gttacataag gatactttat atgtttcata tcgattagga cacgctgata agtcaaccac
    11701 gttgaataca tatagtcatt ggtattattc aggtgattca acaatttcag aagagattac
    11761 aaacagttta gataatcttg gattatcaat ttacctacca aattcctgcc agagttgaaa
    11821 attgaggaat taacccacta atactgggag aaaataggat ttgcaaattg ttactcttaa
    11881 ataatagagt atcgcaattt gattgcggaa tccctattta ccagtctttg agagcgataa
    11941 gcgattgata gaaactgata aattgatttg gtttcctgcc aaaaattctt tggcaggatt
    12001 tttgttttaa taaactttcg ggggtagaca ctagattgtc tacccctttt tttgtgtttc
    12061 ggaggtaatt atgcaaaagg aaggacagtc atcacgtcaa ttcgtgaaga gtcatctcat
    12121 gactatcatg ggagttgata ttgtaaaagc aactcagtta gttgatgaaa tggaacaagt
    12181 aggtttaatc cgatttgatg aatttggaaa tgttggaatt ttagtcttgg agggacaata
    12241 atgaagcgta ttaccgctaa tcaatatcag acatcagagc gttattataa gctccccaaa
    12301 cttttatttg agagtgaacg gtataagaat atgaaactgg aggttaaggt ggtttactca
    12361 gttttaaaag atcggttgga gttgtctttg agcaaaggtt ggattgatga ggatggggct
    12421 atttatttga tttattccaa ttcaaatttg atggcacttt taggctgttc aaagtcaaaa
    12481 ttactctcca tgtgagtttg aagtgacatt tttagatgat taccataaaa aacataacta
    12541 cccactattt tacgaatcct atcttcaaaa cgttatggaa ttccttgaaa gtcaagacat
    12601 aaagaatggg gttgatgcct ttgtagatga tcatcaaaat ct
//
LOCUS       DAVHTH010000053        12542 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.053, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000053 DAVHTH010000000
VERSION     DAVHTH010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12542)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12542)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12542
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.053"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            432..1142
                     /gene="deoD"
                     /locus_tag="VVR63_001651"
     CDS             432..1142
                     /gene="deoD"
                     /locus_tag="VVR63_001651"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEU6129649.1"
                     /translation="MSIHIAAQQGEIADKILLPGDPLRAKFIAENFLGDAVCFNEVRN
                     MFGYTGTYKGHRVSVMGTGMGMPSISIYARELIVDYGVKKLIRVGTAGSLNEEVHVRE
                     LVLAQAAATNSNIVRNDWPQYDFPQIASFDLLDKAYHIAKELGMTTHVGNVLSSDVFY
                     SNYFEKNIELGKWGVKAVEMEAAALYYLAAQYHVDALAIMTISDSLVNPDEDTTAEER
                     QNTFTDMMKVGLETLIAE"
     gene            complement(1165..1689)
                     /locus_tag="VVR63_001652"
     CDS             complement(1165..1689)
                     /locus_tag="VVR63_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
                     /protein_id="HEU6129650.1"
                     /translation="MKITIIGYSGSGKSTLAEKLSNYYSIPKLHMDTLQFQPGWQDSD
                     CEWMLIEIKNFLTKHKAWVIDGNYSWCYYQERMQEADQIIFLNFLPLTCLFRAFKRYL
                     KYRGKVRESMAADCPERFDWEFIRWILWDGRSKTQKENYQKLCQEYSHKVTILRNQRE
                     LDQFLDKKRKSYNS"
     gene            complement(1742..1978)
                     /locus_tag="VVR63_001653"
     CDS             complement(1742..1978)
                     /locus_tag="VVR63_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001274003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HEU6129651.1"
                     /translation="MANIKSAIKRAELNVKQNEKNSAQKSAMRTAIKAFEANPSEELF
                     RAASSAIDKAETKGLIHKNKASRDKARLSTKLAK"
     gene            complement(2046..2966)
                     /locus_tag="VVR63_001654"
     CDS             complement(2046..2966)
                     /locus_tag="VVR63_001654"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HEU6129652.1"
                     /translation="MTNEFLHFEKISRQTWQSLHRKTTPPLTEEELESIKSFNDQISL
                     QDVTDIYLPLAHLIQIYKRTKEDLAFSKGIFLQRESKSQPFIIGVSGSVAVGKSTTSR
                     LLQILLSRTFTDATVELVTTDGFLYPNQTLIEQGILNRKGFPESYDMEALLNFLDRIK
                     NGQDVDIPVYSHEVYDIVPEKKQSVKAADFVIVEGINVFQNPQNDRLYITDFFDFSIY
                     VDAGVDDIESWYLDRFLKMLSLAQNDPDSYYYRFTQMPIGEVESFAHQVWISINLTNL
                     QNYIEPTRNRAEVILHKSKNHEIDEIYLKK"
     gene            3156..3559
                     /locus_tag="VVR63_001655"
                     /pseudo
     CDS             3156..3559
                     /locus_tag="VVR63_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698118.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            3775..4356
                     /locus_tag="VVR63_001656"
     CDS             3775..4356
                     /locus_tag="VVR63_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEU6129653.1"
                     /translation="MYYAENPDAAHDIHELRVDLLGEKMTFLTDAGVFSKKMVDFGSQ
                     LLLKCLDVNQGETVLDVGCGYGPLGLSLVKVYGVQATMVDINTRALDLAQRNAEKNNA
                     KATIFQSNIYARVQGRFDHVISNPPIRAGKQVVHEIIEKSKDFLEIGGDLTIVIQKKQ
                     GAPSAKSKMEDVFGNCEILKKDKGYYILRSVKE"
     gene            4353..5630
                     /locus_tag="VVR63_001657"
     CDS             4353..5630
                     /locus_tag="VVR63_001657"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001202959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HEU6129654.1"
                     /translation="MRAVDLIQKKRDGQELTSSEIEWLIEGYVSGTVPDYQMSAFAMA
                     VYFKGMTTREISDLTMNMVKTGQEFDLSAIDGVKVDKHSTGGVGDKVTLILAPLVASF
                     GVPVAKMSGRGLGHTGGTIDKLESIRGYQVERSQEDFIRQVQDIGVSVIGQSDQLVKA
                     DKLLYALRDVTATVDTIPLIASSVMSKKIAAGADAILLDVTVGEGAFMKTVDEARELA
                     QTMVDLGKVVGRKTVAVITDMSQPLGRAIGNRLEILEALEILQGQGRQDITHFICELA
                     QIMLGLANVNKTVEEVRQHLENGQALAKFEEMVQAQGGDLEDLYRPVNVAHVVEIPAH
                     ETGVISALPAMDFGLYAMRLGAGRAVKSDVLDYETGIVFEKKIGDSVQKGEIVAKVYT
                     NEKIPPQLVTDFQKCVKISDEVKKIREIVEIIS"
     gene            5648..6310
                     /gene="deoC"
                     /locus_tag="VVR63_001658"
     CDS             5648..6310
                     /gene="deoC"
                     /locus_tag="VVR63_001658"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HEU6129655.1"
                     /translation="MKLNKYIDHTLLKQDAKKKQIDSLLSEAREYGFASVCVNPTWVE
                     HAKKGLEGTDVKVCTVVGFPLGATTSTVKAFETKEAIQNGADEIDMVINVGALKSGDL
                     ALVESDIRAVVEASGDKLVKVIIEACLLTDQEKVLACQLAQKAGADFVKTSTGFSTGG
                     ATIADVRLMRETVGPDMGVKAAGGARSYADALTFVEAGATRIGTSAGVAILKGELADG
                     DY"
     gene            6297..6686
                     /locus_tag="VVR63_001659"
     CDS             6297..6686
                     /locus_tag="VVR63_001659"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEU6129656.1"
                     /translation="MATTELIELAIETSKHAYVPYSHFPIGAVLVAKDGSVYTGVNIE
                     NASYPLTNCGERTAIFKAISEGQREFSELIVYGQTEKPISPCGACRQVMVEFFEQDLK
                     VTLVAKDKSTVEMMVGELLPYSFTDLN"
     gene            6777..7829
                     /locus_tag="VVR63_001660"
     CDS             6777..7829
                     /locus_tag="VVR63_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HEU6129657.1"
                     /translation="MNKKQWLGLGLVAVAAVGLAACGNRSSRNAASSSDVKTKAAIVT
                     DTGGVDDKSFNQSAWEGLQDWGKEHNLSKDNGFTYFQSTSEADYANNLQQAAGSYNLI
                     FGVGFALHNAVEEAAKEHTDLNYVLIDDVIKDQKNVASVTFADNESGYLAGVAAAKTT
                     KTKQVGFVGGIESEVISRFEAGFKAGVASVDPSIKVQVDYAGSFGDAAKGKTIAAAQY
                     AAGADIVYQVAGGTGAGVFAEAKSLNESRPENEKVWVIGVDRDQEAEGKYTSKDGKES
                     NFVLVSTLKQVGTTVKDISNKAEKGEFPGGQVIVYSLKDKGVDLAVTNLSEEGKKAVE
                     DAKAKILDGSVKVPEK"
     gene            7973..9508
                     /locus_tag="VVR63_001661"
     CDS             7973..9508
                     /locus_tag="VVR63_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000929819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6129658.1"
                     /translation="MAHENVIEMRDITKVFGGFVANDKINLHLRKGEIHALLGENGAG
                     KSTLMNMLAGLLEPTSGEIAVNGQVVNLDSPSKAASLGIGMVHQHFMLVEAFTVAENI
                     ILGSELTKNGVLDIAGASKEIKALSERYGLAVDPSAKVADISVGAQQRVEILKTLYRG
                     ADILIFDEPTAVLTPSEIDELMAIMKNLVKEGKSIILITHKLDEIRAVSDRVTVIRRG
                     KSIETVEIAGATNADLAEMMVGRSVSFKTEKQASKPKEVVLSIKDLVVNENRGVPAVK
                     NLSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKVESGSIELKGDSIVGLHPRQITEL
                     SVGHVPEDRHRDGLILEMMISENIALQTYYKEPHSKNGILNYSNITSYAKKLMEEFDV
                     RAASELVPAAALSGGNQQKAIIAREIDRDPDLLIVSQPTRGLDVGAIEYIHKRLIEER
                     DNGKAVLVVSFELDEILNVSDRIAVIHDGKIQGIVSPETTNKQGLGVLMAGGNLGKEK
                     SDV"
     gene            9501..10559
                     /locus_tag="VVR63_001662"
     CDS             9501..10559
                     /locus_tag="VVR63_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6129659.1"
                     /translation="MSKKLQQISVPLISVFLGILLGAIVMWIFGYDAIWGYEELFYTA
                     FGSLRGIGEIFRAMGPLVLIGLGFAVASRAGFFNVGLPGQALAGWILSGWFALSHPDM
                     PRPLMILATIVIALIAGGIVGAIPGILRAYLGTSEVIVTIMMNYIVLYVGNAFIHAFP
                     KDFMQSTDSTIRVGANATYQTPWLAELTGNSRMNIGIFFAIIAVAVIWFMLKKTTLGF
                     EIRAVGLNPHASEYAGISAKRTIILSMIISGALAGLGGAVEGLGTFQNVYVQGSSLAI
                     GFNGMAVSLLAANSPIGILFAAFLFGVLQVGAPGMNAAQVPSELVSIVTASIIFFVSV
                     HYLIERFVKPKKQVKGGK"
     gene            10562..11518
                     /locus_tag="VVR63_001663"
     CDS             10562..11518
                     /locus_tag="VVR63_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6129660.1"
                     /translation="MSIITLLPLLVSSMLIYSAPLIFTSIGGVFSERGGVVNVGLEGI
                     MVMGAFSGVVFNLEFAEQFGAATPWLSLLVAGLVGSVFSIIHAAATVHFRADHVVSGT
                     VLNLMAPALAVFLVKVLYNKGQTDNLSQTFGRFDFPVLANIPVIGDIFFKSTSLLGYL
                     AIAFSFLAWFILFKTQFGLRLRSVGEHPQAADTLGINVYKMRYLGVIISGFLGGIGGA
                     IYAQSISVNFSVTTIVGPGFIALAAMIFGKWNPIGAMLSSLFFGLSQSLAVIGSQLPF
                     LQGVPAVYLQIAPYVLTILVLAAFFGKAVAPKADGINYIKSK"
     gene            11603..12542
                     /locus_tag="VVR63_001664"
                     /pseudo
     CDS             11603..12542
                     /locus_tag="VVR63_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT         3680 a         2219 c         2834 g         3809 t
ORIGIN      
        1 ggtttgaaga gattttcgaa gagtataaac agaaaggtag agcgcgtgtt ctaatttgaa
       61 cacgagtaga aaacttttct aaaaacaaaa acgaaaggat gggtaaactg tattcgctga
      121 actgaatacg ggcgactctc ctctaaatca aaattaagaa aggaattgac cccaccctaa
      181 aagtagtggg aaaaagatag ttggtctagc gagcatcgct cactgcgccc aactcctatt
      241 ttcccttcgc tttttgatgg gtttggtatc tttctcaata taaaatataa aataaagaaa
      301 ggtagagcgt gtgttttgat ttgaacacga gcggaaaact cggaaaatag ataatctgac
      361 tgaaaaatca ggatttctcg tcaggttcct aattttcagt cgttttcttc tcgctctttg
      421 tatcataaat tatgtctatc catattgctg ctcagcaggg tgaaattgct gataaaattc
      481 ttcttcctgg ggatcctctt cgtgctaagt ttattgcgga gaatttcctt ggtgatgctg
      541 tttgttttaa cgaagtgcgt aacatgtttg gttacactgg tacttacaag ggtcaccgtg
      601 tatctgtcat gggaactggg atgggaatgc catctatttc gatttatgcg cgtgagttaa
      661 tcgtagacta cggtgtgaag aaattgattc gtgtgggaac tgcaggttct ttgaatgaag
      721 aggttcatgt tcgtgaatta gttttggcgc aggcggctgc aaccaactca aacatcgttc
      781 gtaatgactg gccacagtac gattttccac aaattgctag ctttgatttg cttgataaag
      841 cctaccatat cgccaaagaa cttggtatga ctactcacgt tgggaacgtt ttgtcatctg
      901 atgtctttta ctcaaattac tttgaaaaga atatcgagct tggtaaatgg ggagtcaagg
      961 ctgtggaaat ggaagcagca gctctttact atcttgctgc ccaataccat gttgatgcgc
     1021 tagctatcat gaccatctct gatagcttgg tcaatccaga cgaagacaca actgcagaag
     1081 aacgtcaaaa taccttcact gatatgatga aggttggttt ggaaaccttg attgcagaat
     1141 aattatagcc aaaaaggaag ccctttatga attgtaggac ttccttttct tatccagaaa
     1201 ttgatctagc tctctctgat ttcgaagaat agtgacttta tgtgaatatt cttggcaaag
     1261 tttttggtaa ttttcttttt gagttttgct acgcccatcc caaagaatcc atctgataaa
     1321 ctcccagtca aagcgttcag ggcaatctgc cgccatactt tctctgactt ttccacggta
     1381 tttaagataa cgcttaaagg ctctaaagag acaggtcaat ggcaaaaaat tgagaaagat
     1441 gatttggtca gcttcttgca ttcgttcttg gtagtagcac caagaataat taccatcgat
     1501 gacccaagct ttatgcttgg tgagaaagtt ttttatctcg attaacatcc attcgcagtc
     1561 actgtcttgc caaccaggtt gaaattggag tgtgtccatg tgcagttttg gaatggagta
     1621 gtagttagat aacttttctg ctagagttga cttaccagaa ccagaatatc cgataattgt
     1681 gattttcatt ttctaccttt tcctatttgg agacaaaaaa acagcctcta tggactgttt
     1741 cttatttagc aagtttagtt gaaagacgag ctttatcgcg gcttgctttg tttttgtgaa
     1801 tcaaaccttt agtttctgct ttatcgatag ctgagctagc agcacggaaa agttcttcag
     1861 atgggtttgc ttcgaaagct tttatagcag tacgcatagc tgatttttga gctgagttct
     1921 tttcgttttg tttaacgttc aattcagcgc gtttgatagc tgatttaatg tttgccaatg
     1981 ttcttacctc catatttact aactatacca ttatatatga aaacttacgt tttgacaagg
     2041 gaaaattact tttttaagta aatttcatcg atttcatggt tcttgctttt atgaagaatc
     2101 acttctgcac gatttctggt tggttcaata taattttgca gatttgtgag attgatactg
     2161 atccagacct gatgggcaaa ggactccact tccccaatcg gcatctgagt aaaacgataa
     2221 tagtagctat cagggtcgtt ttgggctagg ctcagcatct tcaagaaacg gtccagatac
     2281 caactttcaa tatcatccac tccagcatct acatagatgg aaaagtcaaa gaagtcagtg
     2341 atatagagac gatcgttttg tggattttga aagacattaa ttccctcaac aattacaaaa
     2401 tcagcagctt tgacactttg tttcttttcg ggtacgatgt cgtaaacttc atgagaatag
     2461 acaggaatat ctacatcttg tccatttttg atgcggtcca agaagttgag aagagcttcc
     2521 atatcatagc tttcaggaaa tcctttacga tttaaaatcc cctgctcaat caaggtttga
     2581 ttgggataga gaaaaccatc agttgtaacc aactcaaccg tagcatctgt aaacgtacgg
     2641 gacagtagga tttgaagtag gcgactggtt gtggattttc caacggcaac actcccagaa
     2701 accccaataa taaaaggttg agatttactt tcacgttgga ggaaaattcc ttttgaaaag
     2761 gctaaatctt ccttagttcg cttgtaaatc tgaatcagat gagccaaggg gagatagata
     2821 tctgtaacgt cttggagact gatttggtca ttaaaactct tgatagattc caattcttct
     2881 tctgtcaaag gaggtgttgt ctttcgatgt aaagattgcc aagtctggcg gctgattttt
     2941 tcaaaatgta aaaattcgtt ggtcatttgt tttcccctag atattttgtc tatcatacca
     3001 taaaaagcta aaaaaataaa gcggtttctt gaatgtggta agtcaatggt atatagtata
     3061 agtgatcaat ttattgatga aataggagat agattctact gatttataag cttataaagg
     3121 gggcttttta gttcacaact tataggaggt gtactatgaa aatcttaaaa cgttacatat
     3181 tggaactctg ttttatttta agttttgctt taccttttat aaaaggaacc aatgcagata
     3241 atggtagatg ctttgtggaa acctattacg gttttacttt tttgatggaa catgctattg
     3301 taacagctgt ctttatctgt tcgttcttaa ttgctttctt actaaaaaac gatggacgaa
     3361 atggattgct gcgggtagtt attgcttttt agtcctacgg attgcgacag agggttattt
     3421 cttccacatg tcactagaag atttgatacg actttggaca agtttggaaa tcctgacaca
     3481 aacgtatcag ttgggctttt atctaaacat tttgttagga attttgttga taataaagta
     3541 ttttaaggtt aagcaataga aataataatc tgcctgatta tagatgataa actttttgtt
     3601 tttatctgga ctgtgatatt tatagttcta aatggtttat tatttataag tgttgaaaga
     3661 gattgaagaa aatggcttcg tgacttgctt tcttcggtct ttttcgtttt attatcaatt
     3721 tgtaaacgat ttacaatttg agtcaaatta tggtaaaata gtgtcatgag taaaatgtac
     3781 tatgcagaaa atcctgacgc tgctcacgac attcatgagt tgagagtgga cttgttggga
     3841 gaaaaaatga cttttttgac agatgcgggt gtttttagca agaaaatggt tgactttgga
     3901 agtcaactct tgctcaagtg tctggatgtc aaccaaggag agacagtcct agatgtaggc
     3961 tgtggttatg gtccattagg tttgtccttg gtcaaggttt acggagttca ggcgaccatg
     4021 gttgatatta acactcgtgc cctggattta gctcagagaa atgctgaaaa aaataatgca
     4081 aaagcgacga tatttcaatc taatatttat gcaagagttc aagggcgatt tgaccatgtc
     4141 atttccaatc ctcctatccg tgcgggcaag caagtcgttc atgaaatcat cgagaaaagt
     4201 aaagatttct tggaaattgg tggagatttg accatcgtca tccagaaaaa acaaggagct
     4261 ccaagtgcca aatctaagat ggaagatgtg tttggcaatt gtgaaatcct taaaaaagac
     4321 aagggatact atatccttag aagtgtgaaa gaatgagagc agttgattta atccaaaaaa
     4381 aacgagacgg tcaagaactg acttcaagtg aaattgaatg gctgatagaa ggctatgtat
     4441 caggaactgt tcctgattat cagatgtctg cctttgctat ggctgtttat tttaaaggaa
     4501 tgacgactcg agaaatctct gatttaacga tgaatatggt taagactggg caagagtttg
     4561 acctgtcagc cattgatggt gtgaaagttg acaagcattc tactggtggt gtcggcgata
     4621 aggtaacctt gattttagct cctcttgttg ctagcttcgg tgtgcctgta gcaaaaatga
     4681 gtggtcgtgg tcttggccat acaggcggaa caattgataa attggagtcc attaggggct
     4741 atcaagtaga acgtagtcaa gaggatttta ttcgtcaggt tcaggatatt ggagtatctg
     4801 tcattgggca atcagaccag ctggtcaaag cagataagct tctctatgcc cttcgtgatg
     4861 tgaccgcaac tgtcgacacg attcctttga ttgcgagttc ggtgatgagc aagaaaattg
     4921 cggcaggggc ggatgctatt ttgctagacg tgactgtcgg tgagggtgcc ttcatgaaga
     4981 cggttgatga ggcgcgtgag ttggctcaaa ctatggtaga tcttggtaag gttgttggac
     5041 ggaagacagt agcagtgatt acggatatga gccagccttt gggacgagcg attggaaatc
     5101 gtctggaaat ccttgaagca ttggagattt tgcaaggtca aggacgtcag gatattaccc
     5161 actttatttg tgaattggct caaattatgc ttggtttggc aaatgttaac aaaactgttg
     5221 aagaagttcg ccaacatctt gaaaatggtc aagcactggc taagtttgag gaaatggtgc
     5281 aagcccaagg tggagacttg gaagacctct atcgtcctgt aaatgtagct catgtggtgg
     5341 aaatccctgc tcatgaaacg ggtgtcattt cagctcttcc agctatggac tttggtcttt
     5401 atgccatgag gctgggtgct ggtcgtgcag ttaagtctga tgtcttggac tatgaaacag
     5461 gaattgtttt tgaaaagaag attggagact ccgttcaaaa gggtgaaatt gttgcaaaag
     5521 tatacacaaa tgaaaaaatt ccacctcaac tagttacaga tttccaaaaa tgtgttaaaa
     5581 taagtgatga agtgaaaaaa atccgtgaaa ttgtagaaat catctcctaa atggagggaa
     5641 aaccgaaatg aaattaaata aatatataga tcatacgctt ttaaaacaag atgcaaagaa
     5701 aaaacaaatt gatagtttgt tgtctgaggc tagagagtat ggctttgcca gtgtttgcgt
     5761 taatccgacc tgggttgaac atgctaaaaa aggacttgaa ggcacagatg ttaaggtttg
     5821 cacagtagta ggtttcccct tgggagcaac aacttcaact gtgaaagctt ttgaaacaaa
     5881 agaagctatc caaaatgggg ctgatgagat tgacatggta atcaatgttg gggctctcaa
     5941 gtcaggtgat ttggccttgg ttgagtcgga tattcgtgca gtagtggaag caagtgggga
     6001 caagttagtg aaagttatta ttgaagcttg ccttctgaca gaccaagaaa aagttttggc
     6061 ttgccaatta gcccaaaaag caggagctga ctttgtcaaa acatctactg gcttttcaac
     6121 tggtggtgct acgatagcag atgttagatt aatgcgtgaa acagttggac ctgatatggg
     6181 tgtcaaggcc gccggtggag ctcgttctta tgcagatgct cttacctttg tcgaagcagg
     6241 tgcgacccgt atcggaacgt cagctggggt agctatttta aaaggagaat tggcagatgg
     6301 cgactactga gttgattgaa ctggcaattg aaaccagcaa acatgcctat gtcccctatt
     6361 ctcactttcc tatcggagca gttttagtag ccaaagacgg aagtgtttac acgggagtga
     6421 atatcgaaaa tgctagctat cctttgacca attgcggtga gagaacagct atttttaagg
     6481 ctatatctga aggccaaaga gaattttcag aattgattgt ctatggtcaa actgaaaaac
     6541 cgatttcacc atgtggtgct tgtcgccaag taatggtcga attttttgaa caagatttaa
     6601 aagtgaccct agtcgcaaaa gataaatcga cggtcgagat gatggtcggg gagttacttc
     6661 catactcttt tacagactta aattagtctg agtcgctctt tgagtggcaa gggtctttgt
     6721 gaccaatcaa tccatacttg caacatcgtt gcacatctta tttaggaggt tcagtaatga
     6781 acaagaaaca atggctaggt cttggcctag ttgcagtggc agcagttgga cttgctgcat
     6841 gtggtaaccg ctcttctcgt aacgcagctt catcttctga tgtgaagaca aaagcagcaa
     6901 tcgtcactga tactggtggt gttgatgaca aatcattcaa ccaatcagct tgggaaggtt
     6961 tgcaagactg gggtaaagaa cacaatcttt caaaagataa cggtttcact tacttccaat
     7021 caacaagtga agctgactac gctaacaact tgcaacaagc ggctggaagt tacaacctaa
     7081 tctttggtgt tggttttgcc cttcacaatg cagttgaaga agcagctaaa gaacacactg
     7141 acttgaacta tgtcttgatt gatgatgtga ttaaagacca aaaaaatgtt gcgagcgtaa
     7201 ctttcgctga taatgagtca ggttaccttg caggtgtggc tgcagcaaaa acaactaaga
     7261 caaaacaagt tggttttgta ggtggtatcg aatctgaagt tatctctcgt tttgaggcag
     7321 gattcaaggc tggtgttgcg tcagtagacc catctatcaa agtacaagtt gactacgctg
     7381 gttcatttgg tgatgcggct aaaggtaaaa caattgcagc cgcacaatac gcagccggtg
     7441 cagatattgt ttaccaagta gctggtggta caggtgcagg tgtctttgca gaggcaaaat
     7501 ctctcaacga aagccgtcct gaaaatgaaa aagtttgggt tatcggtgtt gaccgtgacc
     7561 aagaagcaga aggtaaatac acttctaaag atggcaaaga atcaaacttt gttcttgtat
     7621 ctactttgaa acaagttggt acaactgtaa aagatatttc taacaaggca gaaaaaggag
     7681 aattccctgg cggtcaagtg atcgtttact cattgaagga taaaggggtt gacttggcag
     7741 taacaaacct ttcagaagaa ggtaaaaaag ctgtcgaaga tgcaaaagct aaaatccttg
     7801 atggaagcgt aaaagttcct gaaaaataat ggatggaagt catttcttag gaagcggcca
     7861 agggccgctt ttttaagagt tgagacaaag tcattttgtc tcagtaaagc ttgctactag
     7921 acaaactagc aagttttatt gaaataaaat aagactctga aaggaagagc acatggcaca
     7981 cgaaaatgtc attgagatgc gtgatattac caaggtgttt ggtggatttg ttgccaacga
     8041 caaaatcaac ttgcacctac gaaaaggtga aattcatgca cttttaggag aaaatggggc
     8101 tggtaagtcc acgctaatga acatgttagc aggccttctt gaaccaacca gtggtgaaat
     8161 cgcggtcaac ggtcaagttg tcaatctcga ctccccatct aaagcagcta gcttgggaat
     8221 cgggatggtt caccagcact ttatgttggt tgaagccttc acagtggctg aaaacatcat
     8281 tttaggtagt gaattgacta aaaatggtgt gctagatatc gctggagcta gcaaagaaat
     8341 caaggctctt tctgaacgtt atggcttagc tgttgaccct tctgccaagg tagcagatat
     8401 ctcagttgga gcccaacaac gtgtagaaat tttaaaaaca ctttatcggg gggctgatat
     8461 ccttatcttt gacgaaccaa cggctgtttt gactccatca gaaattgatg agttgatggc
     8521 tattatgaaa aatcttgtca aagaaggaaa atcaattatc ttgattaccc acaaattgga
     8581 tgaaattcgc gcagtttctg accgtgttac agttatccgt cgtgggaaat caattgaaac
     8641 cgttgaaatt gcaggggcta ccaatgctga tttggcggaa atgatggtag gacgttctgt
     8701 ttcctttaaa acagagaagc aagcctctaa accaaaagaa gtggttttgt ctatcaaaga
     8761 tttggtggtc aatgaaaacc gtggtgttcc agctgttaaa aatctgtcct tggatgttcg
     8821 tgctggagag attgttggta ttgcggggat tgatggaaat ggtcagtctg aactgattca
     8881 agccattaca ggtcttcgta aggttgaatc tggtagcatt gagctaaaag gagattcaat
     8941 tgtaggcttg cacccacgtc agattacaga actaagtgtt gggcacgttc cagaagaccg
     9001 tcaccgtgat ggcttgattt tggaaatgat gatatctgaa aatattgccc ttcaaaccta
     9061 ctataaagaa ccacatagta aaaatggaat tttgaattat tcaaatatta cttcttatgc
     9121 taaaaagctg atggaagagt ttgatgttcg cgctgccagt gaattagttc ctgcagctgc
     9181 actctcagga ggaaatcaac aaaaagcaat tattgctcgt gaaattgatc gagatcctga
     9241 tctccttatc gttagccagc caactcgtgg gttggatgtc ggtgccattg agtatatcca
     9301 caaacgcttg attgaagagc gtgataatgg caaggctgtc cttgttgtca gctttgaatt
     9361 ggatgagatt ttaaacgtct cagaccgtat tgccgttatc cacgatggta agattcaagg
     9421 tattgtatca ccagaaacaa ccaataaaca aggacttggt gtcttgatgg ctggtggaaa
     9481 cttgggaaag gagaagagtg atgtctaaaa aattacaaca aatttcggtt cccttgattt
     9541 ctgtattcct aggaatttta ctcggagcca ttgtcatgtg gatcttcggt tatgatgcta
     9601 tttggggcta cgaagaattg ttctatacag cctttggcag tctgcgtggg attggagaaa
     9661 tcttccgtgc tatgggtcct ctggtcttga ttggtcttgg ttttgcggtt gccagtcgag
     9721 ctggtttctt taacgtcgga cttcctggtc aggctttggc aggttggatt ctcagtggtt
     9781 ggtttgccct gtcgcatcca gatatgcccc gtcccttgat gattctagca accatcgtga
     9841 ttgccttgat tgctggtggg attgtcggag cgattccagg tattcttagg gcctatctag
     9901 ggacgtcaga ggttattgta accatcatga tgaactacat tgtcttgtat gtagggaatg
     9961 cctttatcca tgctttccct aaagacttca tgcaaagtac agattcgacc attcgtgttg
    10021 gggctaatgc aacctatcag acaccttggt tagctgagtt gactggtaac tcacggatga
    10081 atattggtat tttctttgcc atcattgccg ttgcagttat ttggttcatg ctcaagaaaa
    10141 caactcttgg ttttgaaatc cgtgcagttg gtcttaatcc acatgcttca gaatatgctg
    10201 gtatttctgc caagcggact attatcctat ctatgattat ttcaggcgcc ttggcaggtc
    10261 ttggtggagc tgttgaaggt ttgggaacct tccagaacgt ctatgttcaa ggttcgtcat
    10321 tagctatcgg atttaacgga atggcggtta gtttgcttgc ggccaactca ccaattggta
    10381 tactctttgc agccttccta tttggcgttc tccaagttgg ggctcctggt atgaatgcgg
    10441 cgcaggtacc atctgagctt gtcagcattg taacagcgtc tattatcttc tttgtcagtg
    10501 ttcattacct tatcgaacgc tttgtcaaac cgaaaaaaca agttaaagga ggtaagtaaa
    10561 gatgtctatt ataaccttgc tccccctctt ggtgtcttct atgctgattt actcagcacc
    10621 tctcatcttt acaagtatcg gtggtgtttt ctctgaacgt ggtggtgtgg taaacgttgg
    10681 ccttgaagga attatggtta tgggtgcctt ttctggagtt gtctttaacc ttgaatttgc
    10741 agaacaattt ggagcagcaa ctccatggct atccttgctt gtagcaggat tggttggtag
    10801 tgttttctct atcatccacg cagcagcgac ggttcatttc cgtgcagacc atgttgtcag
    10861 cggtacggta ttgaacttga tggcgcctgc cttggctgtt ttcttagtta aagttcttta
    10921 taacaaagga caaaccgaca acctaagtca aacttttgga cgctttgatt tcccagtctt
    10981 ggcaaatatc ccagtgattg gtgatatctt cttcaagtca actagtctac ttggttatct
    11041 ggcgattgcc ttctcattcc ttgcttggtt tattctcttt aagactcaat ttggtcttcg
    11101 tctccgctct gtcggtgaac atcctcaagc agcggatacc ttgggaatca acgtctacaa
    11161 gatgagatat ttaggggtta ttatttcagg ttttctaggt ggaattggcg gagcgattta
    11221 tgcgcaatca atctcagtta acttctcagt gacaactatt gttggacctg gatttatcgc
    11281 ccttgctgcg atgatctttg ggaaatggaa tccaatcggt gctatgcttt ctagtctctt
    11341 ctttggactt tcacaaagtt tggctgttat cggttctcaa ttgccgttcc tacaaggagt
    11401 gccagcggtt tatcttcaaa ttgcacctta tgttttgaca attcttgtct tagcagcctt
    11461 ctttggaaaa gcagtcgcac caaaagcaga tggtatcaac tacatcaaat caaaataagc
    11521 atacaaaaaa acgtcagtcc aatgactgaa ctgcccccca aaagttagac agaaaaaatc
    11581 taacttttgg ggtgttttta ttatgaaatt aacttatgat gataaagttc agatctatga
    11641 acttagaaaa caaggatata gcttagagaa gctttcaaat aaatttggga taaataattc
    11701 taatcttaga tatatgatta aattgattga tcgttacgga atagagttcg tcaaaaaagg
    11761 aaaaaatcgt tactattctc ctgatttaaa acaagaaatg attaataaag tctgacatga
    11821 aggctggact aaagacagag tttctcttga atacggtctc ccaagtcgta cgatacttct
    11881 taactggcta gcacaataca gaaaaaaacg ggtatactat tgttgagaaa acaagaggga
    11941 gagtacctaa aatgggacgt aagccaaaaa agagacctga agagaggaca gaattagaac
    12001 atcttcaagc agaaaatgag tacctgagag cggagaatgc catcctaaaa aagttaagag
    12061 aactccgatt gaaggaggaa aaagagaaag aagaaagaca gaaattgttc aagaattaat
    12121 gactgagttt tcgttagata ttcttctaaa agccattaaa ctagctcgtt cgacctacta
    12181 ctatcacttg aaacagctag acaaaccaga taaggaccaa gagcttaaag ctgaaattca
    12241 atccattttt atcgaacaca agggaaatta tgcttatcgt cggatttatt tagaactaag
    12301 aaatcgtggt tatctggtaa atcataaaag agttcaaggc ttgatgaaag tactcaattt
    12361 acaagctaaa atgcgacaga aacgaaaata ttcttctcat aaaggagacg ttggtaagaa
    12421 agcagagaat ctcattcaag gccaatttga aggctctaaa acaatggaac agtgctacac
    12481 agatgtgact gaatttgcca ttccagtaag tactcaaaag ctttacttat caccagtttt
    12541 ag
//
LOCUS       DAVHTH010000054        12138 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.054, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000054 DAVHTH010000000
VERSION     DAVHTH010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12138)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12138)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12138
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.054"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            complement(169..1371)
                     /gene="rpsA"
                     /locus_tag="VVR63_001665"
     CDS             complement(169..1371)
                     /gene="rpsA"
                     /locus_tag="VVR63_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HEU6129661.1"
                     /translation="MNEFEDLLNSVSQVETGDVVSAEVLTVDATQANVAISGTGVEGV
                     LTLRELTNDRDADINDFVKVGEVLDVLVLRQVVGKDTDTVTYLVSKKRLEARKAWDKL
                     VGREEEVVTVKGTRAVKGGLSVEFEGVRGFIPASMLDTRFVRNAERFVGQEFDTKIKE
                     VNAKENRFILSRREVVEAATAAARAEVFGKLAVGDVVTGKVARITSFGAFIDLGGVDG
                     LVHLTELSHERNVSPKSVVTVGEEIEVKILDLNEEEGRVSLSLKATVPGPWDGVEQKL
                     AKGDVVEGTVKRLTDFGAFVEVLPGIDGLVHVSQISHKRIENPKEALKVGQEVQVKVL
                     EVNADAERVSLSIKALEERPAQEEGQKEEKRAARPRRPRRQEKRDFELPETQTGFSMA
                     DLFGDIEL"
     gene            complement(1533..1604)
                     /locus_tag="VVR63_001666"
     tRNA            complement(1533..1604)
                     /locus_tag="VVR63_001666"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1570..1572),aa:Gln,seq:ttg)
     gene            complement(1614..1694)
                     /locus_tag="VVR63_001667"
     tRNA            complement(1614..1694)
                     /locus_tag="VVR63_001667"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1658..1660),aa:Tyr,seq:gta)
     gene            complement(1744..1974)
                     /locus_tag="VVR63_001668"
     CDS             complement(1744..1974)
                     /locus_tag="VVR63_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000037109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HEU6129662.1"
                     /translation="MSKKDKKIEIQVADAKVNVGKDSFEGYTLTIGKKVIGEIAELDG
                     QFAIIKNGNVDSFYKKLEKAVEILIENYNLAK"
     gene            complement(2142..2786)
                     /gene="pcp"
                     /locus_tag="VVR63_001669"
     CDS             complement(2142..2786)
                     /gene="pcp"
                     /locus_tag="VVR63_001669"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HEU6129663.1"
                     /translation="MKILVTGFNPFGGEKINPALEAVKLLPSEINGAEVRWVEIPTVF
                     YKSSEVLEAEILRYQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPI
                     RIDGASAYFSSLPIKAMVQAIKKQGLPAVVSNSAGTFVCNHLMYQALYLVDKKFPNMR
                     AGFMHIPYMMEQVVNKPNTAGMSLCDIVRGIEVAIEAIVDYKDKDLQLVGGETH"
     gene            complement(2801..3724)
                     /locus_tag="VVR63_001670"
     CDS             complement(2801..3724)
                     /locus_tag="VVR63_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HEU6129664.1"
                     /translation="MTELAKQLLELTYIVIGCQFLHTAYCSYKDKTNPVRLGTSAFWT
                     LLSITFIGGSYMPNMSIGIIVILLSLLTLFKQVRIGTLPSLDEMKANIESNRLKNKIF
                     IPVMLMAILALVLAQMIPEFSKISISLAALFATISVLVITNSHPKSLLSENNRMTQQV
                     STSGIVPQLLGALGAIFTVAGVGDVISHLISGIVPSDSRFIGVLAYVLGMVLFTMIMG
                     NAFAAFTVITAGVGVPFVFALGANPIVAGALAMTAGYCGTLLTPMAANFNALPAALMD
                     MKDQNGVIKAQAGVALVMIVIHIFLMYFLAF"
     gene            complement(3721..4410)
                     /locus_tag="VVR63_001671"
     CDS             complement(3721..4410)
                     /locus_tag="VVR63_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HEU6129665.1"
                     /translation="MEWIRLIGIAIIVVGFILKFDTIATVVLAGLVTALVSGVSLVEF
                     LEILGKEFSNQRVLTIFMVTLPLVGLSETFGLKQRSIDLIRKIKGLTVGNFYTVYFFI
                     RELAGFFSIRLGGHPQFVRPLVQPMGEAAAESQLGRKLTEVEDETIKARAAANENFGN
                     FFAQNTFVGAGGVLLIGGTLDQLGYESNYAGIASTSIIVAVITLIVVGIYNYLFDKKL
                     ISKKTRGGEQK"
     gene            complement(4475..5179)
                     /locus_tag="VVR63_001672"
     CDS             complement(4475..5179)
                     /locus_tag="VVR63_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU6129666.1"
                     /translation="MVLSTSAILVACGKTDKEADAPTTFSYVYAVDPASLGYSIATRT
                     SRTDVIGNVIDGLMENDKYGNVAPSQKDYDLNSTGWAPSYQDPASYLNIMDPKSGSAM
                     KHLGITKGKDKDVVAKPGLDKYKKLLEDAVSETTDLEKRYEKYAKAQAWSTDSSLLMP
                     TASSGGSPVVSNVVPFSKPYSQVGIKGEPYIFKGMKLQKDIVTTKEYNEVFKKWQKEK
                     LESNSKYQKELEKYIK"
     gene            complement(5235..6257)
                     /locus_tag="VVR63_001673"
     CDS             complement(5235..6257)
                     /locus_tag="VVR63_001673"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HEU6129667.1"
                     /translation="MTVTIDWENLGFSYMKLPYRYLAHFKNGQWDQGELTEDATLHIS
                     ESSPSLHYGQQAFEGLKAYRTKDGSVQLFRPDENAKRLQRTCDRLLMPQVPTDMFVEA
                     CKAVVRANEEYVPPYGTGGTLYLRPLLIGVGDIIGVKPAEEYIFTIFAMPVGNYFKGG
                     LVPTNFLIQDEYDRAAPNGTGAAKVGGNYAASLLPGKMAKSRHFSDVIYLDPSTHTKI
                     EEVGSANFFGITADNEFVTPLSPSILPSITKYSLLYLAEHRLGLTPIEGDVPIDNLDR
                     FVEAGACGTAAVISPIGGIQHGDDFHVFYSETEVGPVTRKLYNELTGIQFGDIEAPEG
                     WIVKVD"
     gene            complement(6389..8860)
                     /gene="parC"
                     /locus_tag="VVR63_001674"
     CDS             complement(6389..8860)
                     /gene="parC"
                     /locus_tag="VVR63_001674"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HEU6129668.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRI
                     LYSMNKDSNTFDKSYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKNTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSTGISAGYATDIPPHNLAEVIDAAVYMIDHPTAKIDKLMEFLPGPDFPTGAI
                     IQGRDEIKKAYETGKGRVVVRSKTEIEKLKGGKEQIVITEIPYEINKANLVKKIDDVR
                     VNNKVAGIAEVRDESDRDGLRIAIELKKDANTELVLNYLFKYTDLQINYNFNMVAIDN
                     FTPRQVGIVPILSSYIAHRREVILARSRFDKEKAEKRLHIVEGLIRVISILDEVIALI
                     RASENKADAKENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLA
                     AIIGDERTMYNLMKKELREVKKKFATPRLSSLEDTAKAIEIDTASLIAEEDTYVSVTK
                     AGYIKRTSPRSFAASTLEEIGKRDDDRLIFVQSAKTTQHLLMFTSLGNVIYRPIHELA
                     DIRWKDIGEHLSQTITNFETNEEILYVEVLDQFDDATTYFAVTRLGQIKRVERKEFTP
                     WRTYRSKSVKYAKLKDDTDQIVAVAPIKLDDVVLVSQNGYALRFNIEEVPVVGAKAAG
                     VKAMNLKEDDVLQSGFICNTSSFYLLTQRGSLKRVSIEEILATSRAKRGLQVLRELKN
                     KPHRVFLAGAVAEQGFVGDFFSTEVDVNDQTLLVQSNKGTIYESRLQDLNLSERTSNG
                     SFISDTISDEEVFDAYLQEVVTEDK"
     gene            complement(9280..11223)
                     /gene="parE"
                     /locus_tag="VVR63_001675"
     CDS             complement(9280..11223)
                     /gene="parE"
                     /locus_tag="VVR63_001675"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HEU6129669.1"
                     /translation="MSKKEININNYNDDAIQVLEGLDAVRKRPGMYIGSTDGAGLHHL
                     VWEIVDNAVDEALSGFGDRIDVTINKDGSLTVQDHGRGMPTGMHAMGIPTVEVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSNWLEVEITRDGAVYKQRFENGGKPVTTLK
                     KIGTAPKSKTGTKVTFMPDATIFSTTDFKYNTISERLNESAFLLKNVTLSLTDKRTDE
                     AIEFHYENGVQDFVSYLNEDKEILTPVLYFEGEDNGFQVEVALQYNDGFSDNILSFVN
                     NVRTKDGGTHETGFKSAITKVMNDYARKTGLLKEKDKNLEGSDYREGLAVVLSILVPE
                     EHLQFEGQTKDKLGSPLARPVVDGIVADKLTFFLMENGELASNLIRKAIKARDAREAA
                     RKARDESRNGKKNKKDKGLLSGKLTPAQSKNPAKNELYLVEGDSAGGSAKQGRDRKFQ
                     AILPLRGKVVNTAKAKMADILKNEEINTMIYTIGAGVGADFSIEDANYDKIIIMTDAD
                     TDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKKEEVAYAWTDGELEE
                     LRKQFGKGATLQRYKGLGEMNADQLWETTMNPETRTLIRVTIEDLARAERRVNVLMGD
                     KVEPRRKWIEDNVKFTLEEATVF"
     gene            11359..12000
                     /gene="plsY"
                     /locus_tag="VVR63_001676"
     CDS             11359..12000
                     /gene="plsY"
                     /locus_tag="VVR63_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HEU6129670.1"
                     /translation="MITIVLLILAYLLGSIPSGLWIGQVFFQINLREHGSGNTGTTNT
                     FRILGKKAGMATFVIDFFKGTLATLLPIIFHLQGVSPLIFGLLAVIGHTFPIFAGFKG
                     GKAVATSAGVIFGFAPIFCLYLAIIFFGALYLGSMISLSSVTASIAAVIGVLLFPLFG
                     FILSNYDSLFIAIILALASLIIIRHKDNIARIKNKTENLVPWGLNLTHQDPKK"
     gene            complement(12043..>12138)
                     /locus_tag="VVR63_001677"
     CDS             complement(12043..>12138)
                     /locus_tag="VVR63_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEU6129671.1"
                     /translation="IIDYIDYYNNKRIKVKLKGLSPVQYRTKSFG"
BASE COUNT         3507 a         2751 c         2124 g         3756 t
ORIGIN      
        1 aactttgaaa acttcaaaaa acggattttt atcgctctga acatcaaaaa agaaaggacg
       61 aaatttgtcc tttctcaacc ttagctgact tcaacccact acagttgaca aagagccaga
      121 aaaatccctt gtttagtaaa caaaggattt tgtgaatttt caatttgatt aaagttcgat
      181 atcaccaaac aaatcagcca ttgaaaatcc tgtttgtgtt tctggaagtt cgaaatcacg
      241 cttttcttga cgtcttggac gacgtggacg agcagcacgt ttttcttctt tttgtccttc
      301 ttcttgggct ggacgttctt caagagcttt aatagaaagt gatacgcgtt ctgcatctgc
      361 gttaacttca agaactttaa cttgaacttc ttgaccaact ttaagagctt cttttggatt
      421 ttcaatccgt ttgtgtgaaa tttgtgatac gtgaacaagt ccatcgatac ctggcaatac
      481 ttcaacaaat gcaccgaagt cagtcaaacg tttaactgtt ccttctacta catcaccttt
      541 agccaatttt tgctcaacgc catcccatgg tcctggtact gttgctttaa gtgaaagtga
      601 tacacgtcct tcttcttcgt taagatcaag gattttcact tcaatttctt caccaacagt
      661 tacaactgat tttggtgata cgttacgttc atgtgacaat tcagtcaagt gaaccaatcc
      721 gtcaacacca ccaaggtcga tgaaagcgcc gaagcttgtg atacgagcaa ctttaccagt
      781 tacaacatca ccaacagcca atttaccgaa tacttcagcg cgagctgctg cagtagctgc
      841 ttcaacaact tcacgacgtg aaaggatgaa gcggttttct ttagcgttaa cttctttgat
      901 tttagtatca aattcttgac ctacaaaacg ctcagcgtta cgtacgaaac gagtatccaa
      961 cattgaagct gggataaatc cacgaacacc ttcaaattct actgaaagtc cacctttaac
     1021 ggcacgcgtt cctttaacag taacaacttc ttcttcgcga ccaacaagtt tgtcccatgc
     1081 tttgcgagct tcaaggcgtt ttttagatac aaggtatgta actgtatcag tatctttacc
     1141 aactacttga cgaagtacaa gaacatccaa tacttctcct actttaacaa agtcattgat
     1201 atctgcatca cgatcgtttg tcaattcgcg aagagtcaag acaccttcaa caccagttcc
     1261 agagattgca acgttagctt gagtcgcatc aactgtcaat acttcagcac taacaacatc
     1321 accagtctca acttgactaa cgctatttag caaatcttca aattcgttca tctaaaaaat
     1381 cctccaacaa tcaagttttt cttaaacttg acatacttat aatttttttc ctaagcaccc
     1441 gcaaggacat gttcatatca ttcacgtctt tcaattataa aaataaaata ccctaagata
     1501 ttttgctttt tatcttgatt attacctaag aactggggta gctggattcg aaccaacgca
     1561 tgagggagtc aaagtccctt gccttaccgc ttggctatac cccattaatg aaatggagag
     1621 agagggattc gaacccccga acccgaagga gcggatttac agtccgccgc gtttagcctc
     1681 ttcgctatct ctcctacaat caacatggac tattatatca tgaaaatttc aaaaaaacaa
     1741 gacttatttt gctaaattat aattttcaat caaaatttcc acagcttttt ccaatttttt
     1801 ataaaaacta tcgacattcc cattctttat aatggcaaat tgtccgtcta attcggcaat
     1861 ttctccgata acttttttac cgatagtcaa tgtataacct tcaaaactgt ctttaccaac
     1921 attaactttg gcatccgcta cttgaatttc gattttttta tctttcttgc tcatttcata
     1981 cctctcttca ctttttctat tttacaagaa aatcctaaaa ctagcaagaa aaaactctat
     2041 atcaggcttc tctgatatag agttttatgt aaacaacctc aatcgattta gcatagctaa
     2101 tagttagtaa acaagcataa ttgactatcc tttttaggtt atcagtgagt ctcaccgcct
     2161 actaactgca aatccttatc tttgtagtct acaatagctt caatagctac ctctatgcct
     2221 cttacaatat cacatagact cattcctgca gtattcggct tatttactac ttgttccatc
     2281 atatatggaa tatgcatgaa acctgctctc atattaggga attttttatc cactaaataa
     2341 agagcttggt acatcaaatg attgcaaaca aaggttcctg cactattgga tacaactgcc
     2401 ggaagtccct gttttttgat agcttgtacc atcgctttga taggtaaact actaaaatag
     2461 gccgatgctc catcaatacg aatcggtgta tcaattggtt gattgccttc gttatcaggt
     2521 atgcgagcat catcttgatt aatagccact cgttcaggtg ttaagccggt cctgccgcct
     2581 gcttgtccaa tacaaagtac agcatctggt tgatatcgta atatttctgc ctctaaaact
     2641 tctgacgact tataaaaaac cgttggaatt tctacccagc gaacttcagc cccattaatc
     2701 tcagatggta ataattttac agcctccaaa gctggattaa tcttttcacc tccaaaagga
     2761 ttaaaacctg taaccaatat tttcatttta ttttccttta ctaaaatgcg agaaagtaca
     2821 ttaagaatat gtgaataaca atcattacta gagcaacacc tgcttgagcc tttataacgc
     2881 cattctgatc tttcatatcc atcaatgctg ctggtagagc gttaaaatta gcagccattg
     2941 gggtcaataa ggtcccacaa taacctgctg tcatggcaag agcaccagcc acaattggat
     3001 tagctcccag agcaaataca aagggaactc caacacctgc tgtaataacg gtgaatgctg
     3061 caaaagcatt tcccataatc attgtgaata gaaccattcc aagaacatag gccaaaactc
     3121 ctataaagcg actatctgaa ggaacaatac cgctaatcag atgagagata acatcaccaa
     3181 cacctgctac agtaaaaata gcccccaaag cccctaataa ttgaggaaca ataccacttg
     3241 ttgaaacttg ctgagtcatt cgattatttt ctgataacag actcttaggg tgactattgg
     3301 taatcacaag aacagaaatt gtagcaaaca aggcggcaag gctaatcgaa atcttgctaa
     3361 attctggaat catttgcgct aagaccaacg caagtattgc catcagcata actggaataa
     3421 aaattttatt tttcaacctg ttagattcaa tattggcttt catttcatct aaggatggca
     3481 aggttccgat acggacttgc ttaaacaatg ttaacagcga taataggatt acaataatac
     3541 caatactcat atttggcata taggaaccac ctataaacgt aatagacaat agagtccaaa
     3601 atgcagatgt cccaagtcga actgggtttg ttttatcttt ataactacaa taggctgtat
     3661 ggagaaattg acaaccaatc acaatatagg tcaactctaa tagttgcttt gccaactctg
     3721 tcatttttgt tctcctcccc tagtcttttt tgatatcaat tttttatcaa ataaataatt
     3781 gtaaatcccc actacaataa gtgttataac agcaacaata atagatgtag aagcaatccc
     3841 tgcataattg ctttcatagc ctaactgatc taatgttccc cctatcaaga ggactccccc
     3901 agcacctaca aacgtatttt gagcaaagaa atttccaaaa ttttcattcg cagccgcacg
     3961 cgcttttatt gtctcatctt caacctctgt taactttcta cctaattgag actctgcagc
     4021 tgcttctccc ataggttgaa ccaaaggtct gacaaactga gggtgtcctc ctagacgaat
     4081 tgaaaagaaa ccagctaact ctcgaataaa aaaataaact gtatagaagt ttccaactgt
     4141 cagaccttta atctttcgaa tcaaatcgat tgatcgttgc ttgagtccaa aggtttctga
     4201 cagccccaca agaggcaagg taaccataaa aatcgtgagc actcgctgat tgctaaattc
     4261 ttttcccaaa atctccaaaa attcaacgag agaaacacct gaaactaaag ctgtaaccaa
     4321 accagctaag actactgttg caattgtatc aaattttaaa ataaaaccca caacaatgat
     4381 tgctattcct attaatctaa tccactccat atcaaactcc tttatattca aaatgacagt
     4441 attttaaaaa ttttatcaag atcaatacca ttccttattt aatgtatttt tctagttctt
     4501 tttggtattt gctattggat tccaattttt ctttttgcca ttttttaaaa acctcgttat
     4561 attcttttgt tgtaacaata tctttttgca atttcattcc tttaaagata tatggttccc
     4621 ccttaatacc aacttgtgag tatggttttg agaatggtac tacgttactt acaactggag
     4681 aaccaccaga tgaagctgtt ggcatcaata atgaactatc tgtcgaccaa gcttgagctt
     4741 tggcatattt ttcatatctc ttctctaggt cagtggtctc agaaacagca tcttctaaca
     4801 atttcttata tttatccaaa ccaggtttag ctacaacatc cttatctttt cctttcgtaa
     4861 taccaaggtg tttcatggca gaaccagatt ttggatccat aatattcaag taagacgctg
     4921 gatcttgata gcttggagcc catcctgtac tattcaaatc atagtctttt tgagaaggag
     4981 caacattgcc gtatttatca ttttccatca aaccatcaat aacatttcca ataacgtctg
     5041 tcctcgatgt tcgagtcgct atactgtagc ccaatgatgc tggatctact gcatagacat
     5101 aagaaaatgt tgtcggtgca tctgcttctt tatcagtttt tccacaagcc actaaaatag
     5161 ctgacgtgct caggaccact cctgctgtta agagccactt tttctatttc ataaaaaatc
     5221 tcctttggtt tattttaatc tacttttaca atccaacctt ctggcgcttc aatatcgcca
     5281 aactgaatac ccgtcaattc attatataat ttacgcgtca caggacctac ttctgtttca
     5341 ctatagaata catggaaatc atcaccatgt tgaatacctc caattggaga aataaccgct
     5401 gctgtaccac aggcacctgc ctctacaaaa cggtcaagat tatcaattgg aacatcaccc
     5461 tcaataggag ttaatcccaa gcgatgttct gccaaataaa gcaaggaata cttggtaata
     5521 gatggcaaga tagatggact caatggtgtt acaaattcat tatcagctgt aattccaaag
     5581 aagttagctg atccgacttc ttcaatcttt gtatgagttg atgggtccag atagataaca
     5641 tctgagaaat gacgtgactt ggccattttt cctggtaaga gacttgcagc atagtttcca
     5701 ccaaccttag ccgcacctgt accatttggt gctgcacggt cgtactcatc ctgaatcaag
     5761 aagttggttg ggaccaaacc acctttaaag taatttccaa ctggcatagc aaagatggtg
     5821 aaaatgtact cttctgccgg ttttaccccg ataatatctc cgacaccaat caaaagaggg
     5881 cgaagatata aggttccacc tgttccgtat ggtggtacgt attcttcatt cgcacggaca
     5941 actgctttac aagcttctac aaacatgtct gtcggaactt gtggcatcaa gagacggtca
     6001 catgtacgtt gcagacgttt agcattttca tcaggacgga acagttgaac actgccatcc
     6061 ttagtacgat aagctttcaa accttcaaat gcttgttgtc catagtgaag acttggagaa
     6121 gactctgaaa tatgcaaagt tgcatcctct gtaagctctc cttgatccca ttgtccattt
     6181 ttgaaatgag caagatagcg ataaggtaat ttcatatagg aaaaaccgag gttttcccaa
     6241 tcaatcgtta ctgtcatatt ccactcctta ttctaaaaac ctatttctta tattctacac
     6301 tatttttcta aaatagcaag tatattttgt aattttcaga aaatttctcc aataaaaacc
     6361 agctcttaga actgattctt catttcactt atttatcttc agtaactact tcctgaagat
     6421 aagcgtcaaa aacttcttca tctgaaatcg tgtcagaaat gaagcttcca ttgctagtgc
     6481 gttctgacaa gttcaagtct tgcaatcggc tttcatagat tgttccttta ttggattgga
     6541 caagcagagt ttggtcgttc acatccactt ccgtactgaa gaaatcgcca acaaatcctt
     6601 gctctgcaac tgctcctgcc aagaagacac gatgcggttt gtttttcaac tcacgcaaga
     6661 cttgtaatcc tcgtttggca cggctggttg ctagaatttc ctcaatggaa acacgtttca
     6721 agcttccacg ctgggtcaag aggtagaagg acgaagtatt acagataaag ccagattgga
     6781 ggacatcatc ttctttcaaa ttcatagcct tgacacctgc tgccttagca ccgacaaccg
     6841 gaacctcttc gatattgaaa cgcagggcat aaccattttg actaaccaag acaacatcat
     6901 ctagtttaat cggagccact gctacaatct gatctgtatc gtctttgagc ttagcatact
     6961 tgacagactt agatctatag gtccgccatg gagtgaattc ttttcgctct acccgtttga
     7021 tttgaccaag gcgagtcact gcaaagtagg ttgtcgcatc gtcaaactga tccagtactt
     7081 ccacataaag gatttcttca ttcgtttcaa agtttgtgat ggtttggctc agatgctctc
     7141 cgatgtcctt ccaacgaata tctgccaact catggattgg tctgtagatg acatttccaa
     7201 gacttgtgaa catcaagagg tgctgggttg tcttggcaga ttgaacaaaa atcaaacggt
     7261 catcatcacg cttgccaatt tcttccaagg tggaagccgc aaaggaacgt ggactggtac
     7321 gcttgatgta acctgccttg gtcacgctga cgtaggtatc ttcctcagcg ataagactag
     7381 ctgtatcaat ctcaattgct ttcgcagtgt cttctaaaga actcaaacga ggagttgcaa
     7441 atttcttctt gacctcacga agttctttct tcatgagatt gtacatagtc ctttcatcac
     7501 cgataatagc cgccagcata gcaatcttct cacgaagctc tgcttcttct tcctgcaaga
     7561 caaccacatc ggtattggtc aaacggtaca gttgcaaagt tacgatagcc tcagcctgtt
     7621 cttccgtaaa atcatagcta actttgaggt tttccttggc gtccgcctta ttctcagaag
     7681 cacggataag agcaatgact tcatccaaaa tcgaaatcac acgaatcaaa ccttcgacga
     7741 tatggagacg tttctcagcc ttttctttgt caaagcgtga acgcgccaaa atcacttctc
     7801 gacggtgagc gatgtagcta gacaggattg gaacaatccc aacctgacga ggtgtgaaat
     7861 tgtcaatcgc caccatatta aagttgtagt tgatttgtag gtcggtgtac ttaaataagt
     7921 agttgagaac aagctcagta ttagcgtctt tcttaagttc gatagcgata cgaagaccat
     7981 cacggtcaga ctcatcacga acctcagcaa tcccagctac cttgttatta acacgaacat
     8041 catcgatttt cttgactaga ttggccttat tgatttcata aggaatctca gtaataacga
     8101 tttgttcctt accacctttt agcttttcaa tttcagtctt ggaacgaaca accacgcgcc
     8161 ctttcccagt ttcataagct ttcttgattt catcacgacc ctgaataata gcccctgtag
     8221 ggaagtctgg tccaggcaag aattccatga gtttatcaat ctttgcagtt gggtggtcaa
     8281 tcatgtaaac tgcagcatct atgacctcag ctaaattatg gggaggaatg tctgtggcat
     8341 aaccagccga aatcccagtc gaaccattga ccaagaggtt tggaaaggct gctggcaaga
     8401 ccgttggttc tttctccgta tcgtcaaagt tccatgcaaa aggaactgta tttttctcga
     8461 tatcctgaag aaggtaacct gcaatttcag acaaacgtgc ctcagtataa cgcatagccg
     8521 caggaggatc tccgtccata gaaccgttat taccgtgcat ttcaactaga atctcacgat
     8581 ttttccagtt ctgtgacata cgaaccatgg catcatagat agaagaatcc ccgtgtgggt
     8641 ggaaattccc catgatgttc ccgactgact tggccgactt acggtagctc ttgtcaaaag
     8701 tattgctatc cttattcata gaataaagaa tacggcgctg aaccggcttc aacccatcac
     8761 gaatatctgg caaagcccgg tcttgaataa tgtacttgga gtagcgacca aagcgctctc
     8821 ccatgatgtc ctccagggac atgttttgaa tgttagacat aagatacaaa gcccataaaa
     8881 taccaagtga aaatagaaaa ttcttgaagt aagcaaactc acaagagaat ttatcttttt
     8941 cacacagtat ctagggcgtg ttcaactcct ttcaaagaat gtagagtagg tttttatgca
     9001 gtaaaagata ttttacgaga attcctcccg tgttcagtta cgataagtaa ccaaactatc
     9061 ctgtttgtat ttttcaatat gaaaatctgg ttttccaaaa ttagtcttag tttgtgtctt
     9121 agccgctccc ttaagcgcct ctttgagata agcactcata gcagattctt cattaataat
     9181 cctgcaattt tttcaaacca agattttcaa actgcttttt cacatagtca ttcacatccg
     9241 actctaattt ccagtttact aacatattat tttctttcat taaaacactg tcgcttcttc
     9301 tagcgtaaac ttgacattat cttcaatcca tttacggcgt ggttctacct tatctcccat
     9361 gagaacattg acgcggcgtt cggcgcgcgc taaatcttca attgtgacac ggatgagggt
     9421 acgtgtttct gggttcatgg ttgtttccca gagctggtcc gcattcatct caccaagtcc
     9481 tttgtatcgt tggagggtag cgcctttacc gaactgttta cggagttctt ctagttctcc
     9541 gtccgtccaa gcgtaggcca cttcttcttt cttgccttta cctttggaca tcttataaag
     9601 aggtgggagg gcaatataga catgacctgc ctcgactagc ggacgcatgt aacggtagaa
     9661 aaatgtcaag agcaaggtct ggatatgggc accgtcggta tccgcatcgg tcatgataat
     9721 gatcttatca tagttggcat cttcaataga gaagtctgct ccaacacccg caccaatggt
     9781 ataaatcatg gtattaatct cttcattttt gaggatatcc gccatcttgg ccttggctgt
     9841 attgacaacc ttaccacgaa gaggtagaat agcctggaac ttgcggtcac gaccttgttt
     9901 ggcagaacca ccggcagagt ccccctcaac tagatagagt tcattcttag caggattctt
     9961 agattgggct ggggtcaatt tcccagacaa caagccctta tctttcttgt ttttcttccc
    10021 atttcggctc tcatcacgcg ccttacgtgc tgcttcacga gcatcacggg ccttgatagc
    10081 cttgcggatg aggttagaag ctaattcccc attttccata aggaaaaagg tcaacttatc
    10141 agccactatt ccatccacaa ctgggcgagc tagggggctt cctagtttat ccttggtctg
    10201 tccttcaaac tgcaagtgtt cttcaggaac taagatagaa agaacgaccg ctagtccctc
    10261 acgatagtct gaaccttcaa ggtttttatc tttttccttg agaagacctg ttttacgtgc
    10321 atagtcattc atgaccttgg taatggcaga cttgaatcct gtctcgtgcg ttccaccgtc
    10381 cttggtgcga acgttattga caaaggatag aatgttatct gagaatccgt cattgtactg
    10441 gagggctact tccacttgaa aaccattgtc ttccccttca aagtaaagaa ctggcgtcaa
    10501 gatttcctta tcttcgttga gataagaaac aaaatcttgt actccattct catagtggaa
    10561 ctcaatcgct tcatctgttc gcttgtccgt taaagacaag gtcacatttt tcaagagaaa
    10621 ggctgattca ttaaggcgct ctgaaatggt attgtacttg aaatctgtcg tagaaaagat
    10681 agtcgcgtca ggcataaaag taactttggt gcctgtttta gacttgggtg ctgtaccgat
    10741 tttcttcaaa gtcgtgacag gttttccacc attttcgaaa cgttgcttgt aaactgcacc
    10801 atcacgggta atttcaactt ctaaccagtt agaaagggcg ttaacaacgg aagaacccac
    10861 tccgtgaagt ccacctgatg tcttatagcc accttgaccg aatttccctc cggcatgaag
    10921 aatggtaaag ataacctcaa cagttggaat tcccatagcg tgcatacctg tcggcatccc
    10981 acgtccatgg tcttgaaccg ttagactacc gtctttattg atagttacat caatacgatc
    11041 accaaaccca gacaaggctt catcgactgc attatcaacg atttcccaaa ctaggtgatg
    11101 aagaccagcg ccatcggtcg atccaatata catccctgga cgttttcgga ccgcatccaa
    11161 cccttctagc acctgaatag catcatcatt ataattgtta atattgattt ccttttttga
    11221 cacaaggaac ctcctattcg ttcatcttta ctattctaca ggttttccaa ggattttgca
    11281 aaatttttct ttctccgatg tgacaatttc agcagagatt ctctgctttt ctttcccaat
    11341 tcatgatata ataggagtat gattacaata gttttattaa tcctagccta tctgctgggt
    11401 tcgattccat ctggtctctg gattggacaa gtattctttc aaatcaatct acgcgagcat
    11461 ggttctggta acactggaac gaccaacacc ttccgcattt taggtaagaa agctggtatg
    11521 gcaacctttg tgattgactt tttcaaagga accctagcaa cgctgcttcc gattattttt
    11581 catctacaag gcgtttctcc tctcatcttt ggacttttgg ctgttatcgg ccataccttc
    11641 cctatctttg caggatttaa aggtggtaag gctgtcgcaa ccagtgctgg agtgattttc
    11701 ggatttgcgc ctatcttctg tctctacctt gcgattatct tctttggagc tctctatctt
    11761 ggcagtatga tttcactgtc tagtgtcaca gcatcgatcg cggctgttat cggggttctg
    11821 ctctttccac tttttggttt tatcctgagt aactatgact ctctcttcat cgctattatc
    11881 ttagcacttg ctagtttgat tatcattcgt cataaggaca atatagctcg tatcaaaaat
    11941 aaaactgaaa atttggtccc ttggggattg aacctaaccc atcaagatcc taaaaaataa
    12001 aacgccagtt ctgtactgcc cccaaacagt tagacaaata atttatccaa aggatttagt
    12061 tctgtattgc acagggctaa gtccttttag ttttacctta attcgtttgt tgttgtagta
    12121 atcaatatag tctataat
//
LOCUS       DAVHTH010000055        12078 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.055, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000055 DAVHTH010000000
VERSION     DAVHTH010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12078)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12078)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12078
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.055"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            complement(<1..494)
                     /locus_tag="VVR63_001678"
     CDS             complement(<1..494)
                     /locus_tag="VVR63_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HEU6129672.1"
                     /translation="MAKNVVITGATSGIGEAIARAYLEQGEDVVLTGRRIDRLEILKS
                     EFAVSFPNQTVWTFPLDVTDMVMVKTVCSDILETIGRIDILVNNAGLALDLAPYQDYE
                     ELDMLTMLDTNVKGLMAVTRCFLPAMIKVNQGHIINMGSTAGIYAYAGAAVYSATKAA
                     VKTFS"
     gene            complement(536..1162)
                     /locus_tag="VVR63_001679"
     CDS             complement(536..1162)
                     /locus_tag="VVR63_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 and tRNA-binding domain-containing
                     protein"
                     /protein_id="HEU6129673.1"
                     /translation="MIFTYNKEHVGDVLMVIVKNSGDAKLNVERKGKVARVFLKENGE
                     TVAWNIFEVSSLFETAERGQVFLTDEQVARLNQELQAEGFTEEIVNDKEPKFVVGEIV
                     EMVAHPDSDHLNICQVAVASDKTVQIVAGAPNARVGLKTIVALPGAMMPKGNLIFPGE
                     LRGEKSFGMMCSPRELHLPNAPQKRGVLELSEDQVVGTPFDSAKHWTA"
     gene            complement(1178..1495)
                     /locus_tag="VVR63_001680"
     CDS             complement(1178..1495)
                     /locus_tag="VVR63_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HEU6129674.1"
                     /translation="MIQPASLEELASLVEKAGKKVFLFVADWCGDCRYIYPALPEIEE
                     TNPEFTFIRMDRDQYMDLAKLWDVYGIPSLVVLEKDKEIGRFVNRDRKSKEQINDFLA
                     GLK"
     gene            complement(1492..1791)
                     /locus_tag="VVR63_001681"
     CDS             complement(1492..1791)
                     /locus_tag="VVR63_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HEU6129675.1"
                     /translation="MNGMKAKKMWMAGLALLGIGSLALATKKVADDRKLMKTQEELTE
                     IVRDHFSDMGEIATLYVQVYESSLESLVGGVIFEDGRHYTFVYENEDLVYEEEVL"
     gene            complement(2076..2267)
                     /locus_tag="VVR63_001682"
     CDS             complement(2076..2267)
                     /locus_tag="VVR63_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein"
                     /protein_id="HEU6129676.1"
                     /translation="MYYSVDDVVSNAFKKRMILDSFFAFNCSGTMKVSTWVYDKGEWY
                     YVSSSGSMIANDWVKDNGK"
     gene            complement(2428..3102)
                     /locus_tag="VVR63_001683"
     CDS             complement(2428..3102)
                     /locus_tag="VVR63_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6129677.1"
                     /translation="MKKKAFGIVLLVLAAWILLQGNFGIPSLDGKIWPLLGIVFFAYK
                     SIESILRRHLTSAVFTGLLALIIANYAYDLLPVTNHSLIWASILVVLGVGYLTHSSKF
                     WNEKKWWYNGKKTVVTDKEVAFGSGTFYKQDQDLVDDQVEVAFGDAKIYYDNAEMLGD
                     FATLNIEVAFGNATVYVPQHWRVDLKVETSFGAAKADAPVAPTSKTLIIRGDVAFGKL
                     EIVYVK"
     gene            complement(3108..3554)
                     /locus_tag="VVR63_001684"
     CDS             complement(3108..3554)
                     /locus_tag="VVR63_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU6129678.1"
                     /translation="MKLRIEIDGNLEETEIVIKTPTLTDEIADLQRLLQESKAPRLTF
                     YKGTGEYYLDLSEILFFETEGSKIYAHNQKEAYEVRLKLYELESILPRYFNRVSKSTI
                     ANIRQIYSVDKSFSGTGTISFYQTHKEVHVSRHYQSLLKENLRNMR"
     gene            complement(3668..4171)
                     /locus_tag="VVR63_001685"
     CDS             complement(3668..4171)
                     /locus_tag="VVR63_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEU6129679.1"
                     /translation="MKNYQEWYRNISSRLTSRPILLFLLRSFNRLMTVAMPLVYLILL
                     VTTYLQLGLGQQVGVYVLIPASGFVTLSLFRKKINHPRPYETWDICPLLDKDSSGRSM
                     PSRHVFSATIISMACLHASLPIGLVCLIFSALLGLVRVLGGVHYPKDVLVGYACGLVW
                     GFLFFLF"
     gene            complement(4168..4530)
                     /locus_tag="VVR63_001686"
     CDS             complement(4168..4530)
                     /locus_tag="VVR63_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HEU6129680.1"
                     /translation="MSQKLYNMKFAAVYLALIAKVERKGGKAESVHQVTSWLTGYEVS
                     DVLACLDRDVTYGDFFRQAPYYVPERIAITGKICGVRIEEIDDPLMQEIRRLDKLVDW
                     LAKGKTSQQVLEKYEKHK"
     gene            complement(4596..6461)
                     /locus_tag="VVR63_001687"
                     /pseudo
     CDS             complement(4596..6461)
                     /locus_tag="VVR63_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001850459.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
     gene            complement(6493..6942)
                     /locus_tag="VVR63_001688"
     CDS             complement(6493..6942)
                     /locus_tag="VVR63_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEU6129681.1"
                     /translation="MGKPMLVFKRFGHQIHLMVQKEAKRCGIEFMGGPQGQVVHFLDN
                     REKNQDLVLIKDIDQELNITKSVASNLVKRIVQNGLVELEASPVDKRAKFVRLTDKAR
                     SQMQQVKAFFERIDKQLMEDIDEDELLIFEKVLGQLQAKYQGNRRRE"
     gene            complement(7066..7782)
                     /locus_tag="VVR63_001689"
     CDS             complement(7066..7782)
                     /locus_tag="VVR63_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU6129682.1"
                     /translation="MGRKWANIVAKKTAKDGANSKVYAKFGVEIYVAAKKGDPDPESN
                     SALKFVIDRAKQAQVPKHIIDKAIDKAKGNTDETFTEGRYEGFGPNGSMLIVDTLTSN
                     VNRTAANVRAAFGKNGGNMGASGSVSYLFDNKGVIVFGGEDADAVFEQLLEADVDVDD
                     VEAQEGTITVYTAPTDLHKAIVALRESGIEEFQVTELEMIPQSEVELSGEDLETFEKL
                     YSVLEDDEDVQKIYTNVDGF"
     gene            complement(8665..10080)
                     /gene="ply"
                     /locus_tag="VVR63_001690"
     CDS             complement(8665..10080)
                     /gene="ply"
                     /locus_tag="VVR63_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin pneumolysin"
                     /protein_id="HEU6129683.1"
                     /translation="MANKAVNDFILAMNYDKKKLLTHQGESIENRFIKEGNQLPDEFV
                     VIERKKRSLSTNTSDISVTATNDSRLYPGALLVVDETLLENNPTLLAVDRAPMTYSID
                     LPGLASSDSFLQVEDPSNSSVRGAVNDLLAKWHQDYGQVNNVPARMQYEKITAHSMEQ
                     LKVKFGSDFEKTGNSLDIDFNSVHSGEKQIQIVNFKQIYYTVSVDAVKNPGDVFQDTV
                     TVEDLKQRGISAERPLVYISSVAYGRQVYLKLETTSKSDEVEAAFEALIKGVKVAPQT
                     EWKQILDNTEVKAVILGGDPSSGARVVTGKVDMVEDLIQEGSRFTADHPGLPISYTTS
                     FLRDNVVATFQNSTDYVETKVTAYRNGDLLLDHSGAYVAQYYITWDELSYDHQGKEVL
                     TPKAWDRNGQDLTAHFTTSIPLKGNVRNLSVKIRECTGLAWEWWRTVYEKTDLPLVRK
                     RTISIWGTTLYPQVEDKVEND"
     gene            complement(10091..10423)
                     /locus_tag="VVR63_001691"
     CDS             complement(10091..10423)
                     /locus_tag="VVR63_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6129684.1"
                     /translation="MYICIDNSMTKNKELVKNQTFKPALLTRRLVKNFMIEEPDLARN
                     PFTRPTLIDLDKVFMLDNTVIPTSYLARRRRNVSEELYEEILDHLVQPRLISLNKSEF
                     MQLNPGTY"
     gene            complement(10494..11102)
                     /locus_tag="VVR63_001692"
     CDS             complement(10494..11102)
                     /locus_tag="VVR63_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6129685.1"
                     /translation="MSQSSYLSPLLWLKKEADKEKMSATQCQIFFFYYQMFELLFARE
                     SDMKDLCLGTKGFYFSQLEKNLLSGVSRFLKNLEGKVTLKANQEVSARKALFLALTTS
                     QSDWQELAPVFDFYQTIGRLENPSLLSSQDRQHLMWIYQSALEKDYIVKVIGDKHFVL
                     KRQDATKLTARQTQTLEILSQSEDLVNPVYVTLGEKGVLLLD"
     gene            complement(11115..11573)
                     /locus_tag="VVR63_001693"
     CDS             complement(11115..11573)
                     /locus_tag="VVR63_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HEU6129686.1"
                     /translation="MTPEEMYLTERLDVQIAHFLKKSVQHRRRYKVLKITEIVAGFLI
                     AVFCAIPMPGDRYRLISVALSSLGLLCEGIINLYNAKENWISYQKTAQLLEKEKFLYQ
                     CQTEKYAGKTKAFALFVKTCEGLISEEINQWESIQSKEVAASADAPVKKE"
     gene            11698..>12078
                     /locus_tag="VVR63_001694"
     CDS             11698..>12078
                     /locus_tag="VVR63_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HEU6129687.1"
                     /translation="MNYEASKQLTDAQFKRLVSVQRTTFEEMLAVLKTAYQLKHAKGG
                     RKPKLNLEDLLMATLQYVREYRTYEQIAADFGIHESNLIRRSQWVEVTLVQSGVTISR
                     TPLSSEDTVMIDATEVQINRPKKTI"
BASE COUNT         3604 a         2785 c         2165 g         3524 t
ORIGIN      
        1 gaaaaggtct taaccgcagc cttggtagct gagtaaacag cggcaccagc ataggcgtag
       61 attcctgcgg ttgaccccat attgataata tgaccttgat tgacttttat cattgctggc
      121 aagaaacagc gagtaaccgc catcagacct ttaacattgg tatccaacat ggtcaacata
      181 tccaactcct catagtcttg atagggagcc aagtcaagag ccagtccggc gttgttgacc
      241 aagatatcaa tcctccctat cgtttctaga atatcagagc aaacagtctt caccatgacc
      301 atatccgtca catctagtgg aaaagtccag acggtttgat ttggaaagct tactgcaaac
      361 tccgacttga ggatttctaa tctgtctatc cgtcgtcctg ttagaacgac atcctcaccc
      421 tgctccagat aagcacgcgc aatcgcttca ccgattcctg aggttgctcc cgtaatcaca
      481 acattttttg ccatcttatt tccttctagc tggtctatca gatattaaca acttcttagg
      541 cagtccagtg tttagctgag tcaaatggtg ttccgacaac ttggtcttct gataattcaa
      601 gcaccccacg tttttgtgga gcatttggca gatgcaattc acgaggactg cacatcatac
      661 caaaactctt ttcaccacga agttcacctg ggaaaatgag attccctttt ggcatcatag
      721 ctccaggaag cgcgacaatg gttttcaacc ccacacgcgc attgggagct cctgcaacga
      781 tttgtacagt cttatcactt gcgactgcaa cttggcagat gttgaggtgg tcactatctg
      841 gatgggctac catctcaaca atttcaccga caacaaactt aggttcctta tcattaacaa
      901 tttcttctgt aaaaccttcc gcctgcaact cttggttcaa acgagcgact tgctcatctg
      961 tcaaaaagac ttgaccgcgc tctgcagttt caaataaact tgaaacttcg aaaatattcc
     1021 aagccactgt ttccccattt tctttgagga aaacacgggc taccttgcct ttgcgttcca
     1081 cattcagttt ggcatctccg ctatttttca cgatgaccat aaggacatca ccgacatgtt
     1141 ctttgttata cgtaaaaatc attgtttcct ttttctccta tttcaatcct gctaaaaaat
     1201 cgttaatttg ctccttactt ttacggtcgc gattgacaaa acgaccgatt tccttgtcct
     1261 tttctagaac aacaaggcta ggaattccgt aaacatccca gagtttggcc aaatccatat
     1321 actgatctcg gtccattcga ataaaggtga actctggatt ggtctcttca atctctggta
     1381 aggcaggata aatataacga caatcgccac accagtctgc cacaaaaagg aagaccttct
     1441 tgcccgcttt ttccactaaa gatgctaatt cttctaaact tgctggctgt atcataagac
     1501 ttcctcctca tagactaggt cttcattttc atagacaaag gtataatgac ggccatcctc
     1561 aaaaatgacg ccaccaacca agctctccag actgctttcg taaacttgaa cataaagggt
     1621 cgcaatttcc cccatgtcgg aaaaatggtc tcgcacaatc tctgtcaact cttcctgagt
     1681 cttcatgagc ttacggtcat ctgcaacttt tttcgtagca agggcaaggc ttccgatacc
     1741 tagcagagcc aagcctgcca tccacatttt tttagctttc ataccattca ttttaacaca
     1801 aaaaaggctt caggacaaat gaggaagcag cagaaaagca agtaaaaagc ctcttccttt
     1861 aaggaaaagg acttcttata ctaagagcaa actagaaagc tagccgcagg ctgctcaaaa
     1921 cacggttttg aggttgtaga taaggcgacg ttgacgtggt ttgaagagat tttcaaagag
     1981 tattattctt attgccaggc acctaagttg ccaacgtagt aaccatcagg tgtgtaggta
     2041 ttgcgaagca tcttacctga tgaagccaga taatactact tgccattgtc tttgacccaa
     2101 tcattcgcaa tcatggaacc agaagaactt acataatacc attctccctt gtcataaacc
     2161 caagtactga ctttcatggt tcctgagcaa ttaaaggcaa aaaaactgtc caatatcatt
     2221 cgttttttaa aagcattcga cactacatca tctacgctgt agtacataga tacatcaaac
     2281 gtaaaagcca aaatatcgaa aaatatacaa cttttaaagg cagcatttca ttttttaaag
     2341 tctaacaacc atagaactga aatcagagca aggcatcaat ttcctactct atagtacgcc
     2401 tattttgatg gttgaagtga agatttttta tttaacgtag acaatttcca acttcccaaa
     2461 agccacatct ccacggataa tcaaggtttt gctggttggg gctacaggag cgtcagcctt
     2521 agctgcacca aaggaggttt ctactttcaa atctacacgc cagtgttgtg gaacatagac
     2581 ggttgcattt ccgaaggcta cttcaatatt taaagttgca aaatcaccta gcatctctgc
     2641 attatcatag tagattttag catccccaaa agcgacttcc acttggtcat ctacgagatc
     2701 ttgatcttgc ttatagaagg tcccgctacc aaaagcgact tccttatccg tgacgactgt
     2761 ttttttccca ttgtaccacc attttttttc attccagaac ttacttgaat gcgtcagata
     2821 accaacacca agtaccacca agatgctagc ccaaataaga gaatgattgg taactggtaa
     2881 caagtcataa gcgtaatttg caatgatgag cgccagtaaa cctgtaaaaa ctgccgaagt
     2941 gagatgacgt ctaaggatgg actcaatgga cttataagca aaaaaaacaa tacctagtaa
     3001 aggccatatt ttaccatcca aagaaggaat tccaaaattc ccttgcagca agatccaagc
     3061 tgctaaaacc aataaaacaa taccaaatgc tttctttttc atgtttttta cctcatgttt
     3121 cttagatttt cttttaggag ggattggtaa tgccgtgaga catgaacctc cttgtgcgtc
     3181 tgataaaagg aaatggtgcc cgttcctgaa aaggacttgt ccactgagta aatctgacgg
     3241 atgtttgcga tcgttgactt ggaaactcga ttaaaatagc gaggcaagat agactccaac
     3301 tcatagagct tgaggcgaac ctcataagct tccttctggt tatgagcgta gatcttgctc
     3361 ccttctgttt caaagaagag aatttctgac aggtctagat aatattcacc tgtccccttg
     3421 taaaaagtca acctcggagc ctttgactct tgcaagagcc gttgcaagtc tgcaatttca
     3481 tctgtcaaag tgggggtctt gatgacaatt tcagtctcct ctaaattgcc gtcaatctca
     3541 attcgtaact tcatcacatc tcctttctga ctctactata tcaaagctaa gttaggaata
     3601 caagggcaaa aaagcaagtg gtcaatttga agcagtaagt ggttgtagga ctagcttaac
     3661 ttacatgtca gaataggaag aaaaggaatc cccacaccaa accacaagca tagccaacca
     3721 agacatcctt gggataatga acacccccta aaaccctcac caaccccagc aaagctgaaa
     3781 agatcaagca tactaagcca ataggtagac tagcatgcag acaggccatg gagatgatag
     3841 ttgccgaaaa gacatggcga ctgggcatcg accgtcccga actatcctta tcaagaaggg
     3901 gacagatatc ccaagtttca taaggtctcg ggtgattgat tttcttacga aacagggaca
     3961 aggtcacaaa acctgatgca ggaataagca cataaacccc aacttgctga ccaagtccta
     4021 gttgcaggta agtggtgact agcaagatca gatagaccag gggcatggcg actgtcatca
     4081 aacgattgaa actgcgtaat aggaataaaa gaattggacg actagttagt ctggagctga
     4141 tatttcgata ccattcttga taatttttca tttatgcttc tcatactttt ctagaacttg
     4201 ttgagatgtt ttccccttgg caagccaatc cactagcttg tccaagcgac gtatttcctg
     4261 catcagagga tcatcaattt cctcaatacg gacaccgcaa atcttccctg taattgcaat
     4321 tcgttcaggg acataatatg gtgcttgtct aaaaaaatct ccgtaagtaa catccctatc
     4381 cagacaagca agaacatcac tcacttcata ccctgtcaac caactggtca cttggtgaac
     4441 tgactctgcc tttccaccct ttcgctcaac ttttgcaatc aaggctaagt agacagcagc
     4501 aaatttcata ttgtataatt tctgactcat acttctctct ttctatgtgt actagtataa
     4561 ataagaaaaa gaaggccgtc aagccttctt ttgatttatt cttctgcttc atcttctgta
     4621 aattgactat tgtacaagtc agcgtagaag ccaccttgcg ccatcagttc ctcatagttg
     4681 ccttgctcga tgatatttcc atctttcatg accaagatca agtctgcatt tcggatggtt
     4741 gacaagcggt gggcaatgac aaaggatgtg cgtcattcca tcaaacggtc catggctttt
     4801 tggatcaatt cctctgtccg tgtgtcaaca gaagaagtcg cctcatccaa aatcaaaagc
     4861 ggtgcatcct taagaagggc acgagcaata gtcaatagtt gtttttgtcc tacagacaag
     4921 gtcacggtgt catccaagat ggtatcatag ccatctggca aggtcataat aaagtggtga
     4981 attcccacag ccttactagc ttccatcatt cgttcatcac taatccctat ttgattatag
     5041 atgagattgt ctcgaatagt tccttcaaag agccaggtat cctgcaagac cattgaaaag
     5101 gcatcatgca cttctgaacg cgtcatagcc ttggtatcca caccatcaat gcgaatactt
     5161 cccttatcaa tctcatagaa tttcatcaaa agattgacaa tggttgtctt accagcccca
     5221 gtcggcccaa caatggcaac cttttgacca gcatgagctg tcgcagagaa gtcatagtct
     5281 tgaacattga caccgtccac cagaatttct cctgctgaca cgtcgtagaa acgtggaatc
     5341 agattgacca gagttgattt accagaacct gttgacccaa taaaggccac tgtttgacca
     5401 gtttctgctt taaagctaac atgttcaata actgcctccg aatttgccgc atagcggaag
     5461 gtcacatcct taaactcgac ctgacctttg aagttttcat cagtcagctg cacttgaaca
     5521 gggttttgga tagaagaatg caaatctaaa acttgattaa tccgcttagc agagaccata
     5581 gttcggggaa gaacgatgaa gagtgctccc atgagaagga agcccatgac aacctacatg
     5641 gcataagaca tgaaaacaat catgtcacta aagagaggca gacgcgctat cggagcagcg
     5701 tcgttaatca cataggcccc aatccagtaa atcgctacac tcaaaccact tgaaatcccc
     5761 atcatgatag gattcaaaat agccataaga cggttgacaa acaaattcaa acgggtcaat
     5821 tcatcattta ctgctgcaaa tttttcattt tgataatcct ctgcattgta ggcacgaacg
     5881 acacgaatac ctgttaaact ctcacgagtg atactgttca gtttatctat cagcccctga
     5941 atcaaggact gttttggaaa gtctagcgtc atcaaaacgg tcgtcatcag gacgttgaca
     6001 atcactgcca caagtacggc ccaaagccag tattctgaat gacctaaaat cttcccaata
     6061 gcccaaatag ccataattga accacgcgtt accacttgca agcccatagt aatcaacatt
     6121 tgaacttgag taatgtcatt ggtagtacgc gtcaagaggc taggaattga aaatttctta
     6181 atctctgtct gcgagtaatc caaaactcgg ttaaaaatat cacttctcag cctactagta
     6241 taagaagccg ccactcggga tgcaaaaaat ccaactgcaa ctacggacaa gaaggcaaga
     6301 aagagcattc ccatcatcat gcttgccggc tgccacaact catctaaatt agttccttga
     6361 ctacctagca aatccgtaat tttcgagata taggtcggca cttccaactc tagatagacc
     6421 gaaaagcaag taaagagaat ggctagtaaa atcatcccca ttcttttcta ctaattcttt
     6481 tggctaattt ctttattctc tcctcctatt cccttgatat tttgcctgta gttgaccgag
     6541 aactttctca aaaatcagta attcatcttc atcaatgtct tccatcaact gcttgtctat
     6601 gcgttcaaaa aaagccttaa cctgttgcat ctgagaacgt gctttgtccg tcagacgaac
     6661 aaacttagcc cgcttatcaa caggactcgc ctccaattcc accaaaccat tttgcactat
     6721 acgcttaacc agattactag caacagactt ggtaatattg agttcctgat cgatatcttt
     6781 aatcaagacc aagtcttggt ttttctcgcg attatccaaa aaatgcacaa cctgaccttg
     6841 cggcccaccc ataaattcaa tgccgcaacg tttggcttcc ttttgcacca tcaggtgaat
     6901 ttgatgacca aaacgcttaa agactaacat cggtttaccc ataatctccc ccttctaaat
     6961 aaaaatagtt ctctggagaa taattaaatt tctatgagaa ctattttctt gattaaaaaa
     7021 atcccaagtg attttctcac ttaggatcat gttctatagg ttaaattaaa acccatctac
     7081 gttcgtataa atcttttgga cgtcttcgtc gtcttcaaga acgctgtaaa gtttttcaaa
     7141 ggtttcaagg tcttcgcctg acaattccac ttctgactga ggaatcattt ccaattcagt
     7201 cacttggaat tcttcaatac cagactcacg gagggcaacg atagccttgt gaaggtcagt
     7261 tggcgctgtg taaactgtga ttgtaccttc ttgtgcttct acgtcatcca catccacatc
     7321 cgcttcgagc aattgctcaa agactgcgtc cgcatcttca cctccaaata caataacacc
     7381 tttgttgtca aagaggtaag aaacagaacc tgaagcgccc atgtttccgc cgtttttacc
     7441 aaaggctgca cggacattgg ctgctgtacg gttgacgtta gaagtcaaag tatccacaat
     7501 tagcatagaa ccatttggcc caaaaccttc gtaacgtcct tctgtaaagg tttcgtctgt
     7561 gtttcctttg gctttatcaa tcgctttatc gataatgtgt tttggcactt gggcttgttt
     7621 agcacggtcg ataacgaatt tcaaagctga gtttgattct ggatctggat cacctttttt
     7681 agctgctaca tagatttcta caccaaattt tgcatatact ttagagttgg ctccatcttt
     7741 agccgttttc ttggctacga tattggccca tttacgtccc attaggaatc tccttttttc
     7801 acattttaat ctttcttatt ataacacaag tttttttgat tttcactaga ggaaatggat
     7861 tttattagca aatcaagcta ggatagcact ttacctgcta agatggtctt gcctttctat
     7921 ctttttatca acagacactc atccacattc aaaaaacaaa ctagaccatt atctgcaaat
     7981 agaaagtttc agccaagttt gacaaagtca gctcaaatta ctgtttgaag tttgtagata
     8041 taagcgacaa aaacaatcat actgcacctt ttgttgacag tctactccag acatatcata
     8101 gttcaagtaa atactttgaa atccaacagt tcttataggc gctattgtat tccaagaaat
     8161 caatagaaga gtttctaagc aaacctctaa tactcaataa aaatcaaaaa gcaaactaga
     8221 aagctagccg caggttgctc aaaacactgt tttgaggttg cggatagggc tgacctggtt
     8281 tgaagagatt ttcgaagagt ataatttacg tgttcccaag atggagaaat tagactagta
     8341 cactggcact tctaaaccat tgctagcaat tgatttgttc atatttaatt tcattttttc
     8401 cataaatggg tattagatat aaacagcaaa atatttccga tacgtgtcat tcttgaattt
     8461 ccaatcatct aaaacaagta aaggataatc aatcccctgt atatcaagga attggctacc
     8521 ctttttactt ttttacacat tctgtttgat agattcattt taacatcacg agcatactcc
     8581 aatggaaatc gctaggcaag agataaactt tcagatatcc gcagagagat catcgcctct
     8641 ttttgtcgca agcattctcc tctcctagtc attttctacc ttatcttcta cctgaggata
     8701 gagagttgtt ccccaaatag aaatcgtccg cttacgcact agtggcaaat cggttttttc
     8761 ataaaccgta cgccaccatt cccaggcaag cccggtacac tctctaattt tgacagagag
     8821 attacgaaca ttccctttta aaggaatact agtggtaaag tgagccgtca aatcctgccc
     8881 atttctgtcc caagccttag gagtcaagac ttccttacct tgatgatcat aggataattc
     8941 atcccaagta atataatatt gggcaacata ggcaccacta tgatccagca gtaaatctcc
     9001 gtttctgtaa gctgtaacct tagtctcaac atagtctgta ctattttgaa aggtcgcaac
     9061 tacattgtca cgtaaaaaag aagttgtata ggaaatcggc aagcctggat gatctgctgt
     9121 aaagcgactg ccttcttgaa tcaagtcctc taccatgtcc accttgcctg ttacaactcg
     9181 ggcacccgaa cttgggtcgc cccctaaaat aaccgccttc acttctgtat tgtccaaaat
     9241 ctgcttccac tctgtctgag gagctacctt gactcctttt atcaaagctt caaaagcagc
     9301 ctctacttca tcactcttac tcgtggtttc caacttgaga tagacttggc gcccataagc
     9361 aacactcgaa atatagacca aaggacgctc tgcagaaatt cctctctgtt ttaaatcctc
     9421 taccgttaca gtatcttgaa acacatctcc tggattttta acagcatcta cgctgactgt
     9481 ataataaatc tgcttaaaat taacaatctg aatctgcttt tcgcctgaat ggacagagtt
     9541 aaaatcaata tcaagagaat tccctgtctt ttcaaagtca gaaccaaact tgaccttgag
     9601 ttgttccatg ctgtgagccg tgattttttc atactgcatt ctagctggga cattattgac
     9661 ctgaccataa tcttgatgcc acttagccaa caaatcgttt accgctccgc gaacacttga
     9721 attgctgggg tcttccactt ggagaaagct atcgctactt gccaaaccag gcaaatcaat
     9781 actataagtc atcggagcac gatcgaccgc aagaagagtg ggattattct ctaacaaggt
     9841 ctcatccact acgagaagtg ctccaggata gaggcgactg tcgttggtag ctgttacaga
     9901 aatatcactt gtatttgtcg acaagctccg cttctttctt tcgataacaa caaactcatc
     9961 gggtagctga ttaccctctt tgatgaaacg attttcaata ctttctccct gatgggtcaa
    10021 gagtttcttt ttatcgtaat tcatagctag tataaagtca tttactgctt tatttgccat
    10081 cttctacctc ctaataagtt cctggattga gttgcataaa ctcagacttg ttcagcgaaa
    10141 tcagccgtgg ttggactaag tgatccaaaa tttcctcgta caattcttct gagacattgc
    10201 gtcgccgtct ggctagataa gaagtcggaa taaccgtatt atccaacata aataccttat
    10261 ctaagtcaat caaggttggt cttgtaaaag gattacgagc tagatccggc tcttctatca
    10321 taaagttctt gaccaaacgt ctggtcaaga gagctggttt gaaggtctga tttttaacca
    10381 actctttgtt tttagtcatg ctgttgtcaa tacagatata catatgattc ttcacagcca
    10441 aatcgctact aatagtcgga aaaggcaaat aaagaactac aacatctcct ctcttaatca
    10501 agcaagagca cccccttttc tcctaatgta acatagacag gattgaccaa gtcttctgat
    10561 tgactcagaa tttccaaagt ttgagtttgg cgcgctgtca atttagtagc atcttgtctc
    10621 ttcaatacaa aatgcttgtc gccaataacc ttgacaatat aatccttctc caaagctgac
    10681 tggtaaatcc acatcagatg ttgtctgtcc tgagaactca agagagaagg attttcaagc
    10741 ctcccgatag tctgataaaa atcaaaaaca ggagctaact cctgccaatc tgattggcta
    10801 gttgtcaagg ctagaaaaag ggctttgcga gctgatactt cttggttagc cttgagagtt
    10861 actttcccct ccaagttttt tagaaatcgg gaaactccag aaagcaaatt tttctctaac
    10921 tgcgagaaat aaaaaccttt cgttcccaga cataagtctt tcatgtcgct ttctctagca
    10981 aataagagct caaacatttg atagtaaaag aaaaatatct ggcactgggt cgcgctcatc
    11041 ttttccttat cggcttcttt ttttaaccag agcaagggcg acaggtagct ggattgagac
    11101 atttcctcta cctcctactc ttttttaact ggagcatctg cactagctgc cacttctttt
    11161 gactggatac tttcccactg gttaatctcc tctgagataa gaccttcgca tgtcttgaca
    11221 aatagggcaa aagccttggt ctttcctgca tatttctccg tttggcattg atagaggaat
    11281 ttttctttct ccaggagttg cgcagttttt tggtaagaaa tccaattttc ctttgcatta
    11341 tacaaattga taatcccctc acacagcaag ccgagactgg ataaggcaac cgaaatcaaa
    11401 cggtagcgat cacctggcat aggaatagca caaaagacag ctatgaggaa acctgccacg
    11461 atttctgtta tttttaatac cttatagcgc ctacgatgtt gaacgctttt ctttaaaaaa
    11521 tgagctatct gtacgtctaa tcgctctgtc aggtacattt cttctggcgt catattcgta
    11581 actcctttca tttactttga taatcatagt ataacatatt tgaatatcaa agtatagtaa
    11641 aaactggact ataacttatt agacttccta cgaaacaaaa tatggtatag tagttctatg
    11701 aattatgaag caagtaaaca actaactgat gcacaattta agcgtcttgt tagtgttcag
    11761 cgtaccactt ttgaagagat gttagctgta ttaaaaacag cttatcaact taaacacgca
    11821 aaaggtggac gaaaacctaa attaaaccta gaagaccttc ttatggccac tcttcaatat
    11881 gtgcgagaat atcgaactta tgaacaaatt gcggctgatt ttggtattca cgaaagcaac
    11941 ttaatccgtc ggagccaatg ggttgaagta actcttgttc aaagtggtgt tacgatttca
    12001 agaactcctc tcagttctga ggacacggta atgattgatg cgacggaagt acaaatcaat
    12061 cgccctaaaa aaacaatt
//
LOCUS       DAVHTH010000056        11794 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.056, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000056 DAVHTH010000000
VERSION     DAVHTH010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11794)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11794)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11794
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.056"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            <1..128
                     /locus_tag="VVR63_001695"
     CDS             <1..128
                     /locus_tag="VVR63_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HEU6129688.1"
                     /translation="LLSDIFSQNILPARYPVGVVTGLLGSPYLIYLLIKMNRRNI"
     gene            128..922
                     /locus_tag="VVR63_001696"
     CDS             128..922
                     /locus_tag="VVR63_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000677523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6129689.1"
                     /translation="MKGLWSNNLTCGYDEKIILENINIKIPEEKISVIIGSNGCGKST
                     LIKTLSRLIKPLEGEVLLDNKSINSYKEKDLAKHIAILPQSPIIPESITVADLVSRGR
                     FPYRKPFKSLGKDDLEIINRSMVKANVEDLANNLVEELSGGQRQRVWIALALAQDTSI
                     LLLDEPTTYLDISYQIELLDLLTDLNQKYKTTICMILHDINLTARYADYLFAIKEGKL
                     VAEGKPEDILNDKLVKDIFNLEAKIIRDPISNSPLMIPIGKHHVNS"
     gene            1310..1699
                     /locus_tag="VVR63_001697"
     CDS             1310..1699
                     /locus_tag="VVR63_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU6129690.1"
                     /translation="MPKRYLLDGKTPRISATNIDNGILGYYEDIDDKNYRVFENFISV
                     SFLGAVFYHKYKASLDMKIHCLKLKNKELNKEVAFYLTSIIRQALKNTEYKDQISSTV
                     LPDIKIKLPIDSRGTPDWNYMERYRDR"
     gene            1665..1979
                     /locus_tag="VVR63_001698"
     CDS             1665..1979
                     /locus_tag="VVR63_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001835032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6129691.1"
                     /translation="MGITWKDIEIDKEREGEIDKKSTPIFYGEFKNVRLSKEEYKNLK
                     EKLNSHTDIMINKLSRYMESSGKTYQNHYVTILKWYEEDKDKLRQKGLNKKMNYDVGE
                     SL"
     gene            2663..2824
                     /locus_tag="VVR63_001699"
     CDS             2663..2824
                     /locus_tag="VVR63_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6129692.1"
                     /translation="MNNDWNGLADLIANLIAKYAGALDLDNLPDPTPAKNQEMKNSFD
                     MAKTQIETD"
     gene            2916..3764
                     /locus_tag="VVR63_001700"
     CDS             2916..3764
                     /locus_tag="VVR63_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEU6129693.1"
                     /translation="MSKEKIKVYLYTRVSTSIQIEGYSLGAQKSRMKAFAIYNDYEIV
                     GEYEDAGKSGKSIEGRIQFNRMMEDIKSGKDGVSFVLVFKLSRFARNAADVLSTLQIM
                     QDYGVNLICVEDGIDSSKDAGKLMISVLSAVAEIERENIRIQTMEGCIQKAREGKWNG
                     GFAPYGYKLEDGKLFINEEEAVAIRTIFDQYVNTTIGANGISKYLENHGIRKIPRQNG
                     KNPLFDAGLIRKILKNPVYNGKIAFGRRTLEKVHGTRNEYKQVEQDEYLISEGIHEAI
                     VSDEVW"
     gene            3810..4595
                     /locus_tag="VVR63_001701"
     CDS             3810..4595
                     /locus_tag="VVR63_001701"
                     /inference="COORDINATES: protein motif:HMM:NF024800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase zinc beta ribbon domain-containing
                     protein"
                     /protein_id="HEU6129694.1"
                     /translation="MNKGKDTRTHLLSGIVKCPICGVGMFGNKCIKKKKDGTKYKDFY
                     YYGCKHRQMIRGHKCTFSKQIREELLDDAVAEVIVKIVSNPKFASMMQEKINMKVDTS
                     EIEKEIDNYQKELRKSHSTKFKLIEEIDNLDVEDKHYKRRKQDLDDRLYRMYDKIDEL
                     ESSLIDAKAKKQTIEAEKLTGDNIYKVLIYFDKLYKVMNDVERRQLISALISEIQVYE
                     EKQSNGQWLKSITFKLPIIEENLNIGLDNDEQVECVSLLEKRS"
     gene            4863..5429
                     /locus_tag="VVR63_001702"
     CDS             4863..5429
                     /locus_tag="VVR63_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6129695.1"
                     /translation="MVILELYQNDYSKDLVAFDSIEDGKAFVAQIPGYTLETEDGVEV
                     EYFNPKNIPDYMEIIFNGNIVPLSRFMFDPGENVNIIWKEISNLSLKNDRVIEGYSKI
                     DAYVVNNHEVKAYVETRETNYRKAKDFLESRGYEIDRSFFGSEDGEAILYRKKGIEVW
                     HFLCHLDPMFVEIEDVEGYVKEEVGEIQ"
     gene            5751..5939
                     /locus_tag="VVR63_001703"
     CDS             5751..5939
                     /locus_tag="VVR63_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HEU6129696.1"
                     /translation="MATDKNRIMISLDDKNLEKLENLVEDARDRRGMRLTKSQVIELL
                     LNTVDYFDDIMGAIYSKK"
     gene            6001..6816
                     /locus_tag="VVR63_001704"
     CDS             6001..6816
                     /locus_tag="VVR63_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEU6129697.1"
                     /translation="MVVYIRQSKLPSEVSINKYNAQVGAYLQGEEVILYQSFSEIKEL
                     TSEDIVVDYIMETRALLKMMGLNVPVHDYPIELKEFYGRKIYAGILGEIVNIPDNWGK
                     FIKPKAGSKVFTGRVVNETHDLIGIGLPFDYPIWISEVVEFIAEWRCFVLDGRVLDVR
                     PYTGDYHAQFDASVIDEAISCWKDAPIAYGLDIGVTRDGRTLVVEVNDGYALGNYGLS
                     PLKSINFHRARWKEMVKPYFEKMKFLKSNRMLFSKINMVDNQYKKHQNEQGGI"
     gene            6816..7670
                     /locus_tag="VVR63_001705"
     CDS             6816..7670
                     /locus_tag="VVR63_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HEU6129698.1"
                     /translation="MLGAIIGDIVGSVYEWNNIKTKDFPLFRKDCFFTDDTVMTCAVA
                     EAIMNGGQKDDFIDAMKKYGRMYPNADYGARFNAWLNSDNREPYNSFGNGSAMRISPC
                     AWIMDCGFYAKTGMWPSSRGLTSLSAEVTHNHPEGVKGAMATADAIFLCRFYFGGYCR
                     EYEQSINDNPTECKRRIKDYIEKEYDYNLSQTLDEIRPNYRFNETCQETVPQAIIAFL
                     ESRDFEDAIRNAISLGGDSDTLAAITCSIAEAAYGIPDWIKDKAYSYLDEPLKDVVRR
                     WENRIKAY"
     gene            7782..8666
                     /locus_tag="VVR63_001706"
     CDS             7782..8666
                     /locus_tag="VVR63_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEU6129699.1"
                     /translation="MKKAMVIINPTSGGEKALDYKEKLENKAKEYFEYVETKITEKVL
                     DATHFAEEASREQYDAVVVFGGDGTVNEVISGIDERDYIPKLGIIPGGTGNLITKLLE
                     INQDIDGAIDELDFDLTNKIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKFGILT
                     YAVNTMKSVMTDQVFNIKVETENGNYVGEASHVLVLLTNYFADKKIFEENKDGYANIL
                     ILKDASIFSKLSVIPDLLKGDVVANDNIEYIKARNIKISSDSELESDVDGDKSDNLPV
                     EIKVLAQRVEVFSKPKED"
     gene            8829..10568
                     /locus_tag="VVR63_001707"
     CDS             8829..10568
                     /locus_tag="VVR63_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HEU6129700.1"
                     /translation="MELSAIYHGPESEYAYLYKDKKLHIRIRTKKGDIESINLHYGDP
                     FIFMEEFYQDTKEMVKITSGTLFDHWQVEVSVDFARIQYLFELRDTEGQNILYGDKGC
                     VENSLENLHAIGNGFKLPYLHEIDACKVPDWVSNTVWYQIFPERFANGNALLNPEGTL
                     DWDSSVTPKSDDFFGGDLQGIIDHMDYLQDLGITGLYLCPIFESTSNHKYNTTDYFEI
                     DRHFGDKETFRELVDQAHHRGMKVMLDAVFNHIASQSLQWKNVVKNGEQSAYKDWFHI
                     QQFPVTTEKLVNKRDLPYHVFGFEDYMPKLNTANPEVKNYLLKVATYWIEEFNIDAWR
                     LDVANEIDHQFWKDFRKAVLAKNPDLYILGEVWHTSQPWLNGDEFHAVMNYPLSDSIK
                     DYFLRGIKKTDQFIDEINGESMYYKQQISEVMFNLLDSHDTERILWTANEDVQLVKSA
                     LAFLFLQKGTPCIYYGTELALTGGPDPDCRRCMPWERVSSDNDMLNFMKRLIKIRKYA
                     SVIISHGKYSLQEINSDLVALEWKYEGRILKAIFNQSTEDYLLEKEAVALASNCQELD
                     NQLVISPDGFMIF"
     gene            10654..10971
                     /locus_tag="VVR63_001708"
     CDS             10654..10971
                     /locus_tag="VVR63_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000995815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6129701.1"
                     /translation="MNCRGHETRQRIVRDFEVQPKVHIKLLANQQKHSDAGATIEDEY
                     YVFIAESKIDGKKEVIQCCMGAARDFLELINHKGLPLFNPLVGDSHVNNRQEYDNTGS
                     GNL"
     gene            11017..11298
                     /locus_tag="VVR63_001709"
     CDS             11017..11298
                     /locus_tag="VVR63_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6129702.1"
                     /translation="MWLIILWNAKPDTPLFNFKDEVIKYKTYEPFESSIKRVNTTIKN
                     GSKGKTLTEMINGYRADNDIRDEICNFNILKNKIRDMKDQQGNTMESYF"
BASE COUNT         4314 a         1640 c         2365 g         3475 t
ORIGIN      
        1 ttttgttatc agacatattc tctcaaaata ttttaccagc tagatatcca gtaggtgttg
       61 taactggctt gttaggttca ccatacttaa tatacttact aataaaaatg aacaggagga
      121 atatataatg aaaggtctgt ggtcaaataa tcttacctgc ggttatgatg aaaaaataat
      181 cttggaaaat ataaatataa aaatacctga agaaaaaata tcagttatta ttgggtcaaa
      241 tggttgtggg aaatcaacac tcattaaaac cttgtctcga cttataaagc cattagaggg
      301 agaagtattg cttgataata aatcaattaa ttcttataaa gaaaaagatt tagcaaaaca
      361 catagctata ttacctcaat ctccaataat ccctgaatca ataacagtag ctgatcttgt
      421 aagccgtggt cgtttcccct acagaaagcc ttttaagagt cttggaaaag atgaccttga
      481 aataataaac agatcaatgg ttaaggccaa tgttgaagat ctagcaaata acctagttga
      541 agaactttct gggggtcaaa ggcaaagagt atggatagct ctagccctag cccaagatac
      601 aagtatccta cttttagatg agccaactac ttacttggat atctcatatc aaatagaact
      661 attagacctc ttgactgatc taaaccaaaa atataagaca accatttgca tgattttgca
      721 cgatataaat ctaacagcaa gatacgctga ttacctattt gcaattaaag aaggtaaact
      781 tgttgcagag ggaaagcctg aagatatact aaatgataaa ctagttaaag atatctttaa
      841 tcttgaagca aaaattatac gtgaccctat ttccaattcg cctctaatga ttcctattgg
      901 caagcaccat gttaactctt aataattgaa tattggaatt catttaaaag tcgcaaattt
      961 tgaactgacc ctcaaaagtt aggccaaaaa actaactaaa ggaggtcagt tttttaatgg
     1021 caaatacagc acagaattta agataaaatt agtaaaagaa tatcatgaat gaaaaatagg
     1081 atatagagaa taacagcaat attaaaaaga tcaggactga taataaacaa aaagaaagta
     1141 caacgactag ttcaaaagct aaaacttcaa gtaaaaagtt attcaagaaa atctagaaaa
     1201 tactcatcct acaaaggaca ggtaggaaaa atatcagaca acaaaataaa aagaaatatt
     1261 tattaccgaa aaaaagggga aatcgagtta agtaccaaca ggctcatcta ttccaaaaag
     1321 atatttactc gatggaaaaa ctcctagaat tagtgctaca aatattgaca atggtatctt
     1381 aggttactac gaagatatag atgataaaaa ttatagagtt tttgaaaatt ttatatctgt
     1441 ttcattttta ggagcagtct tttatcataa atataaagca agcctagata tgaaaattca
     1501 ttgtttaaaa ttaaaaaata aagaattgaa taaagaagta gcattctatt taacttcaat
     1561 tattaggcaa gctttaaaaa atactgaata taaagatcaa atatctagca cagtattgcc
     1621 agatatcaaa attaaattac cgatagacag tagaggtact ccagattgga attacatgga
     1681 aagatataga gatagataaa gagagagagg gagagataga taaaaagtcc acccccattt
     1741 tttatggaga attcaaaaat gtaaggttaa gcaaagaaga atataaaaat ctaaaagaaa
     1801 aattaaactc acacacagat ataatgataa ataaactatc cagatacatg gaaagcagtg
     1861 gtaagaccta tcaaaaccac tatgtgacaa tcttaaaatg gtatgaagaa gataaagaca
     1921 aactaagaca gaaaggttta aataaaaaaa tgaattatga tgtaggagaa tctttataga
     1981 taaaaagagg tggaaaggca ctattaaaga ctttaagtct aaaaaggtat caaagtatgc
     2041 cagagataaa aaaatataaa tatgacactt taaaggcgat tagaaaatta aagaaatgct
     2101 agaagacttt tagatgacag ttaccaagag ggtctaattt tcactgctac ttatgcagtg
     2161 ggaattggac ctttttatat aagcaaattc tatttcaaaa ttggttacca agaaagactt
     2221 cttttcactg ttaagtataa gagggtaatt tatagaattt tgttacatca agataaatat
     2281 tttctgatgg tcaaatttta aaaagattaa taactttcga taaattttga accttaacaa
     2341 ttgaatagac caagacaaga cgttaattat ttttggagcg taataaccta tccgtcaaga
     2401 tctttcggct gaataattcg gcaaaaaaag ttctgctaaa caaaaagaaa gtgagcgata
     2461 agtaagagtt tgaatatagg gagggatacc ctatccgcta tgaagaaaat gaggataatg
     2521 atacttctaa ggttgaagcc ggctcatccg gaatagaggc ggaggtgaga ttcctatgtt
     2581 gctaatccaa agcacttgtc aatgtcaaaa aacttaatta aacaaataat tattagatat
     2641 aaaactttag aggaggtata tattgaacaa tgactggaat ggattggctg atttaatagc
     2701 aaatctgatt gcaaaatatg ctggtgcttt agatttagat aatctacccg atccaacgcc
     2761 agcaaaaaat caagagatga aaaatagttt tgacatggca aaaacacaaa ttgagacgga
     2821 ctaataaaag tgttataata tacttgaaat gatagtccaa acttaaatta aaaaaattat
     2881 atatgatata gaaaaattat attgaggtta atactatgtc aaaagaaaaa ataaaagtat
     2941 acctctatac acgagtatct acgtcaatac agatagaggg gtattcgtta ggggcacaaa
     3001 aatcacgaat gaaagctttt gctatttaca acgattatga aattgttgga gagtatgaag
     3061 atgccgggaa gtctggcaag tctattgaag gtagaataca gttcaatcga atgatggaag
     3121 atataaaatc tggaaaagat ggagtatctt ttgttcttgt gtttaagtta tcaagatttg
     3181 caagaaatgc cgctgatgtt ctttctacac ttcagataat gcaggattat ggagttaatc
     3241 ttatctgcgt tgaagatggc attgattcat ctaaagatgc tgggaaacta atgatttctg
     3301 ttttatcagc tgtggctgaa atagaaagag aaaacatccg tattcaaaca atggaaggtt
     3361 gcattcaaaa agcaagggaa ggaaaatgga atggtggctt tgctccgtat ggatataaac
     3421 ttgaagacgg caagctgttt ataaatgagg aagaggcagt tgcaataaga acgattttcg
     3481 accagtatgt aaatactacg ataggagcca atgggatatc taaatactta gagaatcatg
     3541 gaattagaaa aatcccaaga cagaatggta agaatccttt gtttgatgca ggtcttataa
     3601 gaaagatatt aaagaatcct gtatataatg ggaaaatagc atttggaaga agaactttag
     3661 aaaaagttca tggtacaaga aatgaatata agcaggttga acaagatgaa tatctaatat
     3721 ctgaagggat acatgaagct atagtttccg atgaagtttg gtaagctgct caggttaagc
     3781 taaaatctca agcaaagaaa tatgagcatg tgaataaagg aaaagataca cgcacacact
     3841 tgctttctgg aattgtaaaa tgcccgatat gtggagtggg aatgtttggg aacaagtgta
     3901 tcaagaaaaa gaaagatggc acaaagtata aagattttta ttactatggt tgtaaacata
     3961 ggcagatgat aagaggtcat aagtgtacat tcagtaagca aattagagaa gaattgttag
     4021 atgatgctgt tgcagaggtg attgtcaaga tagtaagtaa tccgaaattt gcttctatga
     4081 tgcaagaaaa aatcaacatg aaggtggata cctctgaaat agaaaaagaa atagataatt
     4141 accaaaagga attgagaaag agtcattcta caaagtttaa gctaattgag gaaatagata
     4201 atttagatgt tgaagataag cattataaga gaaggaaaca ggatttagat gatagactat
     4261 atcgtatgta tgacaaaata gatgaattag aatcatcact aattgatgcg aaagcaaaga
     4321 aacagactat tgaagctgaa aagcttacag gagataacat atataaggtt ctgatctatt
     4381 ttgataagct ctataaagtc atgaatgatg tagagcgtag gcagttaatt tcagctttga
     4441 tttctgaaat tcaagtttat gaagaaaaac aatctaacgg acaatggcta aaatccatta
     4501 cttttaagct accaattata gaagaaaatc tcaacatagg tttggacaat gatgaacaag
     4561 ttgaatgtgt aagtttatta gagaaacgta gttaatcctc aaaaggttcc ccgaaccttt
     4621 tgagtcccac tgacgcatca cgctgaggcg gtatcgctgt ttgtacgagt tgaagcatca
     4681 gcaaagtaaa agtagatgtt cagccaatgc gacgaggtga gaccgaaggt cgataaggtg
     4741 tgttctgggt ataggactcg taaagtaagt aggaaatatg atgagatgat acagagagcc
     4801 tgaattggtc aggtgacgtg cttatttaca ttagcctgat aatgaaaatg gagagattat
     4861 cgatggttat attggaattg taccaaaatg attattctaa agatttagta gcatttgatt
     4921 ccatagaaga tgggaaagcc tttgtagctc aaatcccggg atacactctg gaaacagaag
     4981 atggtgttga agtggagtat tttaatccta aaaacatacc ggattatatg gaaattattt
     5041 ttaacggaaa tattgttcct ttatctagat ttatgttcga tcctggggaa aatgtaaaca
     5101 ttatttggaa agagatttca aatttatccc tcaaaaatga tagagtgatc gaaggatatt
     5161 caaaaattga tgcatatgtc gttaacaacc atgaagttaa agcctatgtc gaaacaagag
     5221 aaacgaacta tcgtaaagca aaagacttct tagaaagccg cggatatgaa atcgacagaa
     5281 gctttttcgg aagtgaagac ggtgaagcga ttctttacag aaaaaaaggg atcgaagttt
     5341 ggcatttctt gtgtcactta gacccaatgt ttgtagagat tgaagatgta gaaggatatg
     5401 ttaaagaaga agttggagag attcaatagt caaccaaagt tccttgtgag tatatacctt
     5461 tgctagtaaa agagtcaaaa cgttataacg aaggggggga agaaaaccct tgagtgtaag
     5521 tctttttctt gtttagaggg aaagtattag agtagccgct cataatttat actagatttg
     5581 ataactgatt tgagacagat tttatttcta taaatattgt gaaaattttt taataccaaa
     5641 gatttaaagt tactgtgtta aaaatcctct ccacttttaa actaatgtat tataaaagcc
     5701 agttgacaca agtgttacac ctgtgataga attaacttga ggtgatgaaa atggcaaccg
     5761 ataaaaatag aataatgatt agcttggatg ataaaaatct agagaaactt gaaaatttag
     5821 tagaagatgc tagagataga aggggaatgc gactaacaaa gtcccaggtt attgaattac
     5881 tcctaaatac cgttgattat ttcgatgata ttatgggggc tatttactca aaaaaataag
     5941 agcaaaattg ctattatttt ttacaaattg gtgtaacact agtgatatag gagtgatgaa
     6001 atggttgttt atattagaca aagtaaatta ccaagtgagg tttcaattaa taaatacaat
     6061 gctcaagtag gtgcctactt acaaggagaa gaagttattt tatatcaatc tttttctgaa
     6121 ataaaagagt taacaagtga agatatagtt gtagattata taatggagac tagagcatta
     6181 ctaaaaatga tgggcttaaa cgttccggtt catgactatc ctattgagct taaagagttt
     6241 tatggtcgaa agatttatgc tggtatttta ggagagattg tgaatatacc tgataattgg
     6301 ggaaaattta ttaagcctaa agctggttca aaagtcttta ctggaagagt tgttaatgaa
     6361 acccatgatt taataggtat tggtctacct ttcgactatc ctatatggat tagtgaggtt
     6421 gtagaattca tagctgaatg gcgttgtttt gtgttagatg gtcgcgtatt agatgttcga
     6481 ccctatacag gtgattatca tgcacaattt gatgcaagtg taattgatga agcgatatca
     6541 tgttggaaag atgcgccaat agcttatgga ctagatatcg gtgttactcg cgatggcaga
     6601 acacttgttg ttgaagtaaa tgatggttat gcattgggaa attatggcct atctccttta
     6661 aaatcaatca attttcatag agctaggtgg aaagaaatgg taaaacccta ttttgaaaaa
     6721 atgaaatttt taaaatccaa caggatgtta ttttctaaaa taaatatggt agataaccaa
     6781 tataaaaagc atcaaaatga acaaggagga atctgatgct tggagcaatt attggagata
     6841 ttgtcggttc tgtttacgaa tggaacaata tcaaaacaaa ggactttcct ttatttcgga
     6901 aggactgctt ttttacagat gacacggtta tgacctgtgc tgttgcagaa gcaattatga
     6961 atggtggaca aaaagacgat ttcattgacg cgatgaagaa atatggcaga atgtatccga
     7021 atgctgatta cggtgctcgg tttaatgcat ggctaaacag cgataaccgt gagccttata
     7081 atagctttgg gaatggatca gctatgcgta tttctccatg tgcttggatc atggactgtg
     7141 gtttttatgc gaaaactggt atgtggccat catctagagg acttacgagt ctttctgcag
     7201 aggtaactca taatcatcca gaaggtgtca aaggcgctat ggctacagct gatgctatct
     7261 ttctatgtcg tttttacttt ggtggttatt gtagagagta cgagcaatca attaacgaca
     7321 atcctacaga gtgtaaaaga cgaattaagg attatataga aaaagaatac gattacaatc
     7381 tatctcaaac tttagatgaa atccgtccta actatcgttt taacgaaaca tgtcaggaaa
     7441 ctgtccctca agccattatc gcctttcttg aaagtagaga cttcgaagat gcgataagaa
     7501 atgccatctc acttggtggc gacagtgata ctctcgcagc aatcacttgt agcatagcag
     7561 aggcagctta cggtattcct gattggatca aggataaggc ctattcttac ttggatgaac
     7621 ccttaaagga tgtagttagg cgatgggaaa atagaataaa agcgtattaa tctccagtac
     7681 gtcagatttc tcttttctgt attttcattg tataatagga ttacatttac ttgcatgcga
     7741 cgaaatgtaa acatttctgt ttaaaattaa ggataaaatc aatgaaaaaa gcaatggtaa
     7801 ttatcaaccc tacttctggt ggcgagaagg ctttggatta caaagaaaag ctggagaata
     7861 aagcaaaaga atactttgaa tatgttgaaa ccaaaattac cgaaaaagtg ctggatgcaa
     7921 cacattttgc tgaagaagct tctcgtgagc agtatgatgc agtggttgtg tttggtggag
     7981 atggaactgt caatgaagtc atttcaggta ttgatgagag agactacatt cctaagttag
     8041 ggattatccc aggcggtacg ggtaacctca ttacaaaact tttggaaatc aatcaagaca
     8101 tcgatggcgc aattgacgaa ctagattttg atttaaccaa taagattgat atcggtaaag
     8161 caaatgacaa ctattttggt tatatcttta gtatcggttc tctgcctgag gcgattcaca
     8221 atgttgaaat agaggacaaa acaaaattcg gtattttaac ctatgctgta aataccatga
     8281 agtctgtcat gacagatcag gtctttaaca ttaaggttga gacagaaaat ggaaattatg
     8341 ttggtgaagc tagccatgtt ttggtccttt tgacaaatta cttcgctgat aagaaaatct
     8401 ttgaagaaaa caaggacggc tatgccaaca ttttgattct gaaagatgcc tctatattct
     8461 ccaaattatc cgtcattcct gatttattaa aaggggatgt tgtcgcaaat gataatatcg
     8521 agtatatcaa agcgcgtaat attaaaatct cttcagatag tgaattggag tcagatgttg
     8581 acggagataa atcagataac ctacctgtag aaatcaaagt cctagctcag cgagtagaag
     8641 tattttcaaa accgaaagag gattagtata tagagaaagc cttttttaag gctttttgta
     8701 tactttaaaa gatagttcct ttaacaacgg acattccttg caaatagttt acaaaaatag
     8761 tatactggat ttattgagtt tgaaaacgtt tgcgtaaaat ttgaatgaat actttaggag
     8821 acaaattgat ggaattgagt gctatttacc atgggcctga gtcggagtat gcctatcttt
     8881 ataaggataa gaaactccat attcgaattc gaactaagaa aggggacatt gaaagcatca
     8941 acttgcacta tggggaccct tttatcttta tggaggagtt ttatcaggat acaaaagaaa
     9001 tggtcaagat aacttctggt accttatttg accattggca ggttgaagtg tcagttgact
     9061 ttgcacgtat ccagtatctc tttgagctca gagatacaga aggtcaaaat attttgtatg
     9121 gcgataaagg gtgtgtggaa aattctctag aaaatcttca tgcaattggg aatggattta
     9181 agttgcctta tcttcatgag attgatgcct gcaaggttcc tgactgggtt tcaaatacgg
     9241 tatggtatca gatatttcct gaaagatttg ccaatggcaa tgctctatta aacccagaag
     9301 ggactttaga ctgggattca tctgtcacac ctaagagcga tgatttcttt ggtggtgatt
     9361 tacaggggat tattgatcat atggattact tgcaagactt gggtattact ggactatatc
     9421 tttgtcccat ctttgaatct acaagcaatc acaagtacaa tacgacagat tactttgaaa
     9481 ttgaccgtca ttttggagac aaggagacct ttcgggaact ggtggatcaa gcgcatcatc
     9541 gtggcatgaa agtcatgctg gatgcggtat ttaatcatat tgcttcgcaa tctcttcaat
     9601 ggaaaaatgt cgtcaaaaat ggtgaacagt ctgcttataa ggattggttc catattcaac
     9661 aattcccagt gacaactgaa aagctagtta ataagagaga cttaccctat catgtttttg
     9721 gtttcgagga ctatatgcct aagctaaata cagccaatcc agaggtcaag aattatcttt
     9781 taaaggttgc gacttattgg attgaagagt ttaatatcga tgcttggcgt ttggatgtgg
     9841 ctaatgagat tgaccatcag ttctggaagg attttcgtaa ggcagtttta gctaaaaatc
     9901 ctgatcttta tatcctagga gaagtctggc atacatctca gccttggcta aatggagatg
     9961 agttccatgc cgtcatgaat tatcctttat ctgatagtat caaggactat ttcttacgag
    10021 gaattaagaa gacagaccag ttcatcgatg aaatcaatgg agagtctatg tattacaagc
    10081 agcagatttc agaggtcatg tttaatctct tggattcaca tgatacagag cgaatcctgt
    10141 ggacggccaa tgaagatgtt caactggtta aatcagcctt agcctttctc tttttacaaa
    10201 aaggaacacc gtgcatttat tacggaaccg agctagcctt gactggagga ccagatccag
    10261 attgtcgtcg ttgtatgcct tgggaacgtg tatcaagtga caatgatatg ctgaacttta
    10321 tgaagaggct gattaagatt cggaaatacg cgtcagtaat catttcgcat ggcaagtata
    10381 gccttcaaga aatcaactct gatctagtag ctctggaatg gaaatacgaa ggacggatcc
    10441 tcaaagcaat attcaaccaa tcaacagaag attatctttt agagaaagaa gcagtagcac
    10501 tagcaagcaa ttgccaagaa ttggataatc agcttgtcat ctctccagat ggatttatga
    10561 ttttctaaaa actagttgat gaagattatg gtacatttca taccttatat agtataataa
    10621 ggctagttac taaacttgta aaggagaact taaatgaatt gtagaggaca tgaaacaaga
    10681 caaagaattg ttagagattt tgaagttcag cctaaagtac atattaagct gttagcaaat
    10741 caacaaaaac atagtgatgc aggagcaact attgaagatg aatattatgt atttatcgct
    10801 gagagtaaaa ttgatggcaa gaaggaagtt attcagtgtt gcatgggtgc ggcaagggat
    10861 tttttagaac taattaatca caaagggtta cctcttttta atccgcttgt aggtgattct
    10921 catgtaaata atagacaaga atatgacaat acagggagtg gaaatttata acctgaaaag
    10981 tggaatgaaa ctgcaaagca gctttataat gctataatgt ggttgattat tttatggaat
    11041 gctaagccgg atacaccttt atttaatttt aaagacgaag taattaagta taaaacatat
    11101 gagccttttg aaagcagtat aaaaagagta aatactacta taaagaatgg tagtaaaggg
    11161 aaaactctga ctgagatgat taatggctac agagcggata acgatattag agatgaaatt
    11221 tgtaacttta atattctgaa aaataaaatt cgtgatatga aagaccaaca aggaaataca
    11281 atggaatctt acttttagtt attgttgaat tttgggtatt ctataaaata tcctaattga
    11341 gatttaaata gtagactata caatatagtt aaaatatcag taaaaacaac actttattga
    11401 ggtattggat acgctttgct aatagcctaa taatcacatg tggagtgttg ctacaacgaa
    11461 aaaggcgata atccttgatt tcaaactatt ttataagcat tttgtctttg tagataaagg
    11521 caattttgac aataaaaatc ctaaaaggtg aatcgttata gatgtatttg tagatatcgt
    11581 ttgcgcatcg aaaaaattaa tacaagaata aatatttatg gctctttagg tgacttttat
    11641 agaagtaaag tttaggatag aaaaacaaga aataatgcac catttttggt gcattatgct
    11701 tttttatgct ataattgaat tataaaaata aaggagtttg ccatgattgg aaagaacata
    11761 aaatccttac gtaaaacaca tgacttaaca caac
//
LOCUS       DAVHTH010000057        11525 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.057, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000057 DAVHTH010000000
VERSION     DAVHTH010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11525)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11525)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11525
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.057"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            <1..170
                     /locus_tag="VVR63_001710"
     CDS             <1..170
                     /locus_tag="VVR63_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="choline-binding protein A"
                     /protein_id="HEU6129703.1"
                     /translation="KDGDTWYYLEASGAMKASQWFKVSDKWYYVNGSGALAVNTTVDG
                     YGVNANGEWVN"
     gene            complement(400..1380)
                     /gene="dusB"
                     /locus_tag="VVR63_001711"
     CDS             complement(400..1380)
                     /gene="dusB"
                     /locus_tag="VVR63_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HEU6129704.1"
                     /translation="MTNLNTPFMIGNVEIPNRTVLAPMAGVTNSAFRTIAKELGAGLV
                     VMEMVSDKGIQYNNEKTLHMLHIDEGENPVSIQLFGSDEDSLARAAEFIQENTKTDIV
                     DINMGCPVNKIVKNEAGAMWLKDPDKIYSIINKVQSVLDIPLTVKMRTGWADPSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGHADLETLYKVAQALTKIPFIANGDIRTVQEAK
                     QRIEEVGADAVMIGRAAMGNPYLFNQINHYFETGEILPDLTFEDKMKIAYEHLKRLIN
                     LKGENVAVREFRGLAPHYLRGTSGAAKLRGAISQASTLAEIEALLQLEKA"
     gene            complement(1367..2239)
                     /gene="hslO"
                     /locus_tag="VVR63_001712"
     CDS             complement(1367..2239)
                     /gene="hslO"
                     /locus_tag="VVR63_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HEU6129705.1"
                     /translation="MDKIIKTISESGAFRAFVLDSTETVRTAQEKHQTQASSTVALGR
                     TLIASQILAANEKGNTKLTVKVLGSSSLGAIITVADTKGNVKGYVQNPGVDIKKTATG
                     EVLVGPFVGNGQFLVITDYGTGNPYNSITPLISGEIGEDLAFYLTESQQTPSAVGLNV
                     LLDEEDKVKVAGGFLVQVLPGAKKEEIARFEKRIQEMPAISTLLESDDHIEALLKAIY
                     GDEAYKRLSEEEIRFQCDCSHERFMNALASLPSSDLQEMKEEDHGAEITCQFCQTTYN
                     FDEKDLEELIRDKS"
     gene            2404..3831
                     /locus_tag="VVR63_001713"
     CDS             2404..3831
                     /locus_tag="VVR63_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU6129706.1"
                     /translation="MYLGDLMEKAECGQFSILSFLLQESQTTVKAVMEETGFSKATLT
                     KYVTLLNDKALDSGLELTIHSEDENLRLSIGAATKGRDIRSLFLESAVKYQILVYLLY
                     HQQFLAHQLAQELVISEATLGRHLAGLNQILSEFDLSIQNGRWRGPEHQIRYFYFCLF
                     RKVWSSQEWEGHMQKPERKQEIANLEEICGASLSAGQKLDLVLWAHISQQRLRVNACQ
                     FQVIEEKMRGYFDNIFYLRLLRKVPSFFAGQHIPLGVEDGEMMIFFSFLLSHRILPLH
                     TMEYILGFGGQLADLLTQLIQEMKKEELLGDYTEDHVTYELSQLCAQVYLYKGYILQD
                     RYKYQLENRHPYLLMEHDFKETAEEIFHALPAFQQGTDLDKKILWEWLQLIEYMAENG
                     GQHMRIGLDLTSGFLVFSRMAAILKRYLEYNRFITIEAYDPSRHYDLLVTNNPIHKKE
                     QTPVYYLKNDLDMEDLAGIRQLLFT"
     gene            3990..5498
                     /gene="glpK"
                     /locus_tag="VVR63_001714"
     CDS             3990..5498
                     /gene="glpK"
                     /locus_tag="VVR63_001714"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HEU6129707.1"
                     /translation="MSQEKYIMAIDQGTTSSRAIIFNKKGEKVSSSQKEFTQIFPQAG
                     WVEHNANEIWNSVQSVIAGAFIESGVKPNQIEAIGITNQRETTVVWDKKTGLPIYNAI
                     VWQSRQTAPLAEQLKNQGYVEKFHEKTGLIIDAYFSATKVRWILDHVEGAQERAEKGE
                     LLFGTIDTWLVWKLTDGAAHVTDYSNAARTMLYNIKELKWDDEILEILNIPKAILPEV
                     RSNSEIYGKTAPFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GEEMQLSENNLLTTIGYGINGKVYYALEGSIFIAGSAIQWLRDGLRMVENSPESEKYA
                     RDSHNNDEVYVVPAFTGLGAPYWNQNARGSVFGLTRGTSKEDFIKATLQSIAYQVRDI
                     IDTMQVDTQTAIQVLKVDGGAAMNNFLMQFQADILGIDIARAKNLETTALGAAFLAGL
                     SVGYWKDLDELKLLNETGELFEPSMNESRKEQLYKGWKKAVKATQVFAEVDD"
     gene            5540..7366
                     /gene="glpO"
                     /locus_tag="VVR63_001715"
     CDS             5540..7366
                     /gene="glpO"
                     /locus_tag="VVR63_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HEU6129708.1"
                     /translation="MEFSKKTRELSIKKMQERTLDLLIIGGGITGAGVALQAAASGLE
                     TGLIEMQDFAEGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKPDP
                     MLLPVYDEDGATFSLFRLKVAMDLYDLLAGVSNTPTANKVLSKDQVLERQPNLKKEGL
                     VGGGVYLDFRNNDARLVIENIKRANQDGALIANHVKAEGFLFDESGKITGVVARDLLT
                     DQVFEIKARLVINTTGPWSDKVRNLSNKGTQFSQMRPTKGVHLVVDSSKIKVSQPVYF
                     DTGLGDGRMVFVLPRENKTYFGTTDTDYTGDLEHPKVTQEDVDYLLGIVNNRFPESNI
                     TIDDIESSWAGLRPLIAGNSASDYNGGNNGTISDESFDNLIATVESYLSKEKTREDVE
                     SAVSKLESSTSEKYLDPSAVSRGSSLDRDDNGLLTLAGGKITDYRKMAEGAMERVVDI
                     LKAEFDRSFKLINSKTYPVSGGELNPANVDSEIEAFAQLGVSRGLDSKEAHYLANLYG
                     SNAPKVFALAHSLEQAPGLSLADTLSLHYAMRNELALSPVDFLLRRTNHMLFMRDSLD
                     SIVEPVLDEMGRFYDWTEEEKATYRADVKAALAQNDLAELKN"
     gene            7436..8140
                     /locus_tag="VVR63_001716"
     CDS             7436..8140
                     /locus_tag="VVR63_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEU6129709.1"
                     /translation="MMNELFGEFLGTLILILLGNGVVAGVVLPKTKSNSSGWIVITMG
                     WGIAVAVAVFVSGKLSPAHLNPAVTIGVALKGGLPWASVLPYILAQFAGAMLGQILVW
                     LQFKPHYEVEENAGNILATFSTGPAIKDTVSNLISEILGTFVLVLTIFALGLYDFQAG
                     IGTFAVGTLIVGIGLSLGGTTGYALNPARDLEPRIMHSILPIPNKGDGDWSYAWIPVV
                     GPVIGAALAVLVFSLF"
     gene            8437..8640
                     /locus_tag="VVR63_001717"
     CDS             8437..8640
                     /locus_tag="VVR63_001717"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6129710.1"
                     /translation="MPKWSNPDYVNELDPKIVDMLVEFHKSQGTLETPEAQAEIAQKR
                     EEIEQRRAELEGKKQELLNRLNK"
     gene            complement(8727..9314)
                     /locus_tag="VVR63_001718"
     CDS             complement(8727..9314)
                     /locus_tag="VVR63_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6129711.1"
                     /translation="MFVFADDSLSANSKVVSGEAQFENGSSVRFGDTQVNILSDEVLE
                     VVNPDGSVDTIERRADGVYINGAFYMAYQKNEIDLNISFRSYDPNVWNYVNTIHGNKQ
                     ANTFANFMTGAGISYMIGRIGALLGGPWGAIIGGAYFGIQAYQSYLDSQSPYPYYITS
                     TYIHVAQRKWKFITEYYRNSNYTGYVKTVTTYVNF"
     gene            10462..10836
                     /locus_tag="VVR63_001719"
     CDS             10462..10836
                     /locus_tag="VVR63_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="reverse transcriptase/maturase"
                     /protein_id="HEU6129712.1"
                     /translation="MLEAYNQVKSNKGSAGIDGMTIEEMDNYLRQNWRLTKELIKQRK
                     YKPQPVLKVEIPKPDGGIRQLGIPTVMDRMIQQAIVQVMSPICEPHFSDTSYGFRPNR
                     SCEKAIMKLLEYLNDGYEWIVD"
     gene            10821..11429
                     /locus_tag="VVR63_001720"
     CDS             10821..11429
                     /locus_tag="VVR63_001720"
                     /inference="COORDINATES: protein motif:HMM:NF012307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6129713.1"
                     /translation="MDSGLDLEKFFDTVPQDRLMSLVHNIIEDGDTESLIRKYLHSGV
                     IINGQRYKTLVGTPQGGNLSPLLSNIMLNELDKELEKRGLRFVRYADDCVITVGSEAA
                     SKRVMYSVSRFIEKRLGLKVNMTKTKITRPRELKYLGFGFWKSSDGWKSRPHQDSVRR
                     FKLKLKKLTHRKWSIDLTRRIEQLNLSIRGWINYFSLGNMKV"
     gene            11390..>11525
                     /locus_tag="VVR63_001721"
     CDS             11390..>11525
                     /locus_tag="VVR63_001721"
                     /inference="COORDINATES: protein motif:HMM:NF019984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6129714.1"
                     /translation="MDKLFLIGKYESIVASIDERLRTRLRVIIWKQWKKKSRRLWGLL
                     K"
BASE COUNT         3411 a         2245 c         2632 g         3237 t
ORIGIN      
        1 tgaaagatgg agatacctgg tactatcttg aagcatcagg tgctatgaaa gcaagccaat
       61 ggttcaaagt atcagataaa tggtactatg tcaatggctc aggtgccctt gcagtcaaca
      121 caactgtaga tggctatgga gtcaatgcca atggtgaatg ggtaaactaa acctaatata
      181 actagttaat actgacttcc tgtaagaact ctttaaagta ttccctacaa ataccatatc
      241 ctttcagtag ataatatacc cttgtaggaa gtttagatta aaaaataact ctgtaatctc
      301 tagccggatt tatagcgcta gagactacgg agtttttttg atgaggaaag aatggcggca
      361 ttcaagaggc tctttaagag agttacgggt tttaaactat taagccttct ccaattgcaa
      421 gagggcttca atctctgcca gggtgctagc ttgcgaaatg gctccacgga gtttggcagc
      481 gccagatgtt ccacggaggt agtgaggagc gaggccgcgg aattcacgaa ctgcgacgtt
      541 ttctcctttg aggttaatca atcgtttcaa gtgttcgtag gcgatcttca tcttgtcttc
      601 aaaggtcaaa tcaggtagga tttctcctgt ttcaaagtaa tggttgattt ggttgaagag
      661 gtaaggattt cccatggcag ctcggccaat catgactgcg tcagcaccaa cttcttcgat
      721 gcgttgcttg gcttcttgga cagtacggat atcaccgttg gcgatgaatg gaatcttggt
      781 tagagcttgg gcaaccttgt aaagggtctc aaggtctgcg tggccagtat acatttgttc
      841 acgggtacgg ccatgcatgg cgagggcaga aacacctgca gcctcagcag cgagggcatt
      901 ctctactgcc agagatgggt ccgcccagcc ggtacgcatt ttgacagtaa gtgggatatc
      961 aaggacagac tggaccttgt tgatgataga gtagatcttg tcaggatcct tgagccacat
     1021 agcaccagct tcgttcttca cgattttgtt gacagggcag cccatgttga tatcgacgat
     1081 atcggtctta gtgttttctt ggataaattc tgctgcgcgt gctaggctgt cttcatcgct
     1141 accaaaaagt tggatagaga cagggttttc gccctcatcg atatgaagca tgtgcagggt
     1201 tttttcgttg ttgtattgga ttcccttgtc agagaccatt tccattacaa cgagtccagc
     1261 tccgagctct tttgcaatgg tacgaaaggc tgagttggtc acgccagcca taggcgctaa
     1321 aacggtacga ttgggaatct caacattgcc aatcataaaa ggtgtattaa gatttgtcac
     1381 gaatgagttc ctccaggtcc ttttcatcaa agttgtaagt agtttggcag aattgacaag
     1441 tgatttctgc cccgtggtct tcctctttca tttcctgtaa gtctgagctt ggaaggctgg
     1501 caagagcgtt cataaagcgt tcatggctac agtcacattg gaaacggatt tcttcttcag
     1561 aaagacgctt gtaggcctcg tcaccgtaga tagccttgag gagggcttcg atatggtcgt
     1621 cgctttcgag aagagtagag atagctggca tttcttggat gcgtttttca aagcgagcaa
     1681 tctcttcttt cttggctcct ggcaagactt gaactaggaa accacctgca accttgacct
     1741 tgtcttcctc gtccaaaagg acattgaggc cgaccgctga aggcgtttgt tggctttcag
     1801 taaggtaaaa ggcaaggtct tcaccgattt ctccagagat gaggggagtt atagagttgt
     1861 aaggatttcc agtaccgtag tctgtgataa caaggaattg accatttcca acaaaaggtc
     1921 cgactaggac ttcaccagtc gcagtctttt tgatgtcaac accaggattt tgaacatagc
     1981 ctttgacgtt ccccttggta tcagcgacgg tgataatagc acctagagag ctagagccca
     2041 acaccttaac tgtaagtttg gtatttcctt tttcattggc tgcgagaatc tggctggcga
     2101 taagagttcg accaagcgct acagttgagc tagcttgggt ttgatgtttt tcttgagcag
     2161 tgcggacggt ttcagtgcta tcaaggacaa aagcacgaaa ggctccgctt tctgatatag
     2221 ttttaataat tttatccata gctactattt tagcataaaa atgcccaaag ggggagccgt
     2281 gtgtttactg attttcagga taatggacca ggaaatcagc atgaaaataa aaagagaaac
     2341 agattatttt agcatttgta agatttatgc tatgcttaag gtagaaaatg aaaggggtaa
     2401 caaatgtatt taggagattt gatggagaaa gccgagtgtg gtcaattttc aatcctttcc
     2461 tttctattac aagagtctca gacgaccgtc aaggctgtaa tggaagaaac aggattttca
     2521 aaagcaaccc taaccaaata tgtcaccctg ctcaatgaca aggctttgga tagtggctta
     2581 gagctgacta ttcactcaga agatgaaaat ctgcgtctgt ctatcggtgc agctaccaag
     2641 gggagagata ttcggagctt gtttttggag agtgctgtta aataccagat tttggtttat
     2701 cttctctacc accaacagtt tttagcccat cagctggctc aagaattagt gattagcgag
     2761 gctacgcttg gtcgtcactt ggctggttta aatcagattt tgtcagaatt tgatttatcc
     2821 atccaaaatg gacgttggcg aggtccagag catcagattc gctatttcta tttctgtctt
     2881 ttccgaaagg tctggtcgag tcaggaatgg gaaggtcaca tgcagaaacc agagagaaaa
     2941 caggagattg ccaatttaga ggaaatctgc ggtgcaagtt tgtctgcggg acagaaattg
     3001 gacttggttc tctgggctca catcagtcaa caacgtcttc gggtcaatgc ttgtcagttt
     3061 caagtcatag aagagaaaat gcgagggtat tttgacaata tcttctatct tcgtttgctg
     3121 agaaaggttc cgtccttttt tgctgggcaa catattccac taggagttga ggatggtgag
     3181 atgatgatat tcttctcttt tctcctatct catcgcattc ttcctcttca tactatggaa
     3241 tatattcttg gttttggagg gcagttggca gatttactga cgcaattgat tcaagaaatg
     3301 aagaaggagg aactattggg ggattataca gaggaccatg tcacctatga actcagtcag
     3361 ctttgtgctc aagtctatct ctataagggc tatattttac aggatcgcta caagtaccag
     3421 ttagagaatc gtcatccata tttactgatg gaacatgatt ttaaagagac agcagaggag
     3481 atttttcatg ctctacctgc ttttcaacag gggacagatt tagataagaa gattctctgg
     3541 gaatggctcc agttaatcga atatatggct gaaaacggtg gccagcatat gcggattggt
     3601 ctggatttga catctggttt tcttgtcttt tcaaggatgg cagccatttt gaaacggtat
     3661 ttggaataca atcgttttat taccattgaa gcttatgacc ctagtcggca ttatgatttg
     3721 ctggttacca ataacccgat tcataagaag gaacagacac cagtctatta tttaaaaaat
     3781 gacttggata tggaggattt ggcagggatt cgtcagttat tattcactta aaaggcttgg
     3841 ttaatccagg tcttttttgt gaaattcaca caatctcctc acattttttt aaaaattaaa
     3901 aaaagttgat aaacaagaaa gcgctttatt ttgtatacta gtaagtgtaa agaggaaaca
     3961 cctcaagatc tttatcagga ggacagtata tgtcacaaga aaaatacatc atggccattg
     4021 accagggaac tacaagttct cgtgccatca ttttcaacaa aaaaggggaa aaggttagct
     4081 cgagtcaaaa agagtttacc cagattttcc ctcaggcagg ttgggttgag cacaatgcca
     4141 atgaaatttg gaactctgtt cagtcagtta ttgcgggtgc tttcatcgaa agtggtgtca
     4201 agccaaatca aatcgaggca atcgggatta ccaaccaacg tgaaacaacg gttgtctggg
     4261 ataagaaaac aggacttcct atctacaatg ctatcgtttg gcagtcacgc cagacagcac
     4321 ctttggctga gcaactaaaa aaccaaggtt atgtggaaaa attccatgaa aagactggtt
     4381 tgattattga tgcttacttc tctgctacca aggttcgttg gattttggat catgtagaag
     4441 gcgctcaaga gcgagcagaa aaaggggaat tgctctttgg tactatcgat acttggttgg
     4501 tttggaaatt gactgacggt gcggctcacg tgactgacta ctcaaatgca gctcgtacca
     4561 tgctttataa cattaaagaa ctcaaatggg atgatgaaat tttggaaatc cttaacattc
     4621 cgaaggctat acttccagaa gttcgttcta actccgaaat ctacggcaag acagctccat
     4681 tccatttcta cggtggagag gtgccaatct caggtatggc tggggaccaa caagcagccc
     4741 tctttggaca gttggctttt gagccaggta tggttaagaa tacttatgga acaggctctt
     4801 tcatcatcat gaatactggg gaagagatgc agttgtctga aaacaacctc ttgacaacca
     4861 ttggttacgg aatcaacggt aaggtttatt atgccttgga aggttctatc ttcatcgcag
     4921 gaagtgctat tcagtggctt cgtgacggtc ttcgcatggt tgaaaattca ccagaatctg
     4981 aaaaatacgc tcgtgattct cacaacaacg atgaagttta tgtcgttcca gcctttacag
     5041 gtctaggcgc tccatactgg aaccaaaatg ctcgtggttc cgtctttggt ttgactcgtg
     5101 gaacaagcaa agaagacttt atcaaggcga ctttgcaatc tattgcttat caagtgcgtg
     5161 acatcatcga caccatgcaa gtggatactc agaccgccat tcaagtactg aaggtggatg
     5221 gtggtgcagc catgaacaac ttcctcatgc aattccaggc ggatatttta ggcattgaca
     5281 ttgcacgtgc taaaaacttg gaaacaacag ctctaggagc ggccttccta gcaggtttgt
     5341 cagtagggta ctggaaagac ttggacgagt tgaaactctt gaacgagaca ggagaactct
     5401 ttgagccatc tatgaatgaa tctcgcaagg aacaactcta caagggctgg aagaaggctg
     5461 tgaaagcaac tcaagtcttt gcggaagtag acgactaata ctggcagaat aaagcgattt
     5521 atttagaaag tgtgtaaata tggaattttc aaagaaaaca cgtgaattgt caattaaaaa
     5581 aatgcaggaa cgcaccctgg acctcttgat tatcggtgga ggaatcacag gagctggtgt
     5641 agccttgcag gcggcagcta gcggtcttga gactggtttg attgaaatgc aagactttgc
     5701 agaaggaaca tctagtcgtt caacaaaatt ggttcacgga ggacttcgtt acctcaaaca
     5761 attcgacgtc gaagtggtct cagatacggt ttctgaacgt gcagtggttc aacaaatcgc
     5821 tccacacatt ccaaaaccag acccaatgct cttaccagtt tacgatgaag atggagcaac
     5881 ctttagcctc ttccgtctta aagtagccat ggacttgtac gacctcttgg caggtgttag
     5941 caacacacca actgcgaaca aggttttgag caaggatcaa gtcttggaac gccagccaaa
     6001 cttgaagaag gaaggcttgg taggaggtgg agtgtatctt gacttccgta acaacgatgc
     6061 gcgtctcgtg attgaaaaca tcaaacgtgc caaccaagac ggtgccctca ttgccaacca
     6121 cgtgaaggca gaaggcttcc tttttgacga aagtggcaag attacaggtg ttgtagctcg
     6181 tgatctcttg acagaccaag tatttgaaat caaggcccgt ctggttatta atacaacagg
     6241 tccttggagt gataaagtac gtaatttgtc taataaggga acgcaattct cacaaatgcg
     6301 cccaactaag ggagttcact tggtagtgga ttcaagcaaa atcaaggttt cacagccagt
     6361 ttactttgac acaggtttgg gtgacggtcg tatggtcttt gttctcccac gtgaaaacaa
     6421 gacttacttt ggtacaactg atacagacta cacaggtgat ttggagcatc caaaagtaac
     6481 tcaagaagat gtagattatc tacttggcat tgtcaacaac cgctttccag aatccaacat
     6541 caccattgat gatatcgaaa gcagctgggc aggtcttcgt ccattgattg cagggaacag
     6601 tgcctctgac tataatggtg gaaataacgg taccatcagt gatgaaagct ttgacaactt
     6661 gattgcgact gttgaatctt atctctccaa agaaaaaaca cgtgaagatg ttgagtctgc
     6721 tgtcagcaag cttgaaagta gcacatctga gaaatatttg gatccatctg cagtttctcg
     6781 tgggtctagc ttggaccgtg atgacaatgg tcttttgact cttgctggcg gtaaaatcac
     6841 agactaccgt aagatggctg aaggagctat ggagcgcgtg gttgacatcc tcaaagcaga
     6901 atttgaccgt agctttaaat tgatcaattc taaaacttac cctgtttcag gtggagaatt
     6961 gaacccagca aatgtggatt cagaaatcga agcctttgcg caacttggag tatcacgtgg
     7021 tttggatagc aaggaagctc actatctggc aaatctttac ggttcaaatg caccgaaggt
     7081 ctttgcactt gctcacagct tggaacaagc gccaggactc agcttggcag atactttgtc
     7141 ccttcactat gcaatgcgca acgagttggc tcttagccca gttgacttcc ttcttcgtcg
     7201 taccaaccat atgctcttta tgcgtgatag cttggatagc atcgttgagc cagttttgga
     7261 tgaaatggga cgattctatg actggacaga agaagaaaaa gcaacttacc gtgctgatgt
     7321 aaaagcagct cttgctcaaa acgacttagc agaattaaaa aattaagaaa aaataaaaga
     7381 ggtggagggc agcattcctt gtcgcccgtc ccttcttttt aatggagaca gaaagatgat
     7441 gaatgaatta tttggagaat ttctagggac tttaatcctg attcttctag gaaatggtgt
     7501 tgttgcaggt gtggttcttc ctaaaaccaa gagcaatagc tcaggttgga ttgtgattac
     7561 tatgggttgg gggattgcag ttgcggttgc agtctttgta tctggcaagc tcagtccagc
     7621 tcatttaaac ccagctgtga ccatcggtgt ggccttaaaa ggtggtttgc cttgggcttc
     7681 cgttttgcct tatatcttag cccagttcgc aggggccatg ctgggtcaga ttttggtttg
     7741 gttgcaattc aaaccgcatt atgaggtaga agaaaatgca ggcaatatcc tggcaacctt
     7801 cagtactgga ccagccatca aggatactgt atcaaacttg attagcgaaa tccttggaac
     7861 ctttgttttg gtgttgacaa tctttgcttt gggtctttac gattttcagg caggtatcgg
     7921 aacctttgca gtgggaactt tgattgtcgg tatcggtcta tcactaggtg ggacaacagg
     7981 ttatgccttg aacccagctc gtgaccttga acctcgtatc atgcacagca tcttgccaat
     8041 tccaaacaag ggagacggag actggtctta cgcttggatt cctgttgtag gccctgttat
     8101 cggagcagcc ttggcagtgc ttgtattctc acttttctag tttatactct tcgaaaatca
     8161 aattcaaacc acgtcagcgt cgccttaccg tactcaagta cagcttgcgg ctagcttcct
     8221 agtttgctct ttgattttca ttgagtatta gaaaacaatt attttgatag agcttgggca
     8281 agagcccaat ttcagcaaaa aatgaagtaa atcttttcat aataaaacgc atcatatcaa
     8341 gcacgaaaat tccacgaggt caactacagt cagaaagctg aacaacaagc caaaacgccc
     8401 aaaaaaggcg gcaaaaagca agcacctgca agcaacgtgc cgaaatggtc aaatcctgat
     8461 tatgtcaacg aattagaccc aaaaatcgtt gatatgctag tagaatttca caagtcacaa
     8521 ggcactttgg aaactcccga ggcgcaagca gaaatcgccc aaaaacgtga agaaatcgag
     8581 caaaggagag ctgagcttga gggtaaaaaa caagagcttt tgaaccgctt gaacaaatag
     8641 agtttcgcaa gtattatgct tacaaattac ttgagcaatt aactaaaata taaaccctgc
     8701 ctttatatct aggcagggtt tatattttag aaattcacgt aggttgttac ggtttttaca
     8761 tacccagtat agtttgagtt tctatagtat tcagtgataa acttccattt tctttgagca
     8821 acatggatat aagtacttgt tatgtagtat ggatatgggc tttgtgaatc caagtaagac
     8881 tgataagctt gtataccaaa atatgctcca ccaattattg caccccatgg accccccaat
     8941 aaagcaccta tcctaccaat catataactg attccagcac cagtcatgaa gttagcgaat
     9001 gtgttagctt gtttattccc atgtattgtg ttgacgtaat tccaaacatt aggatcgtat
     9061 gatctaaaag atatatttag gtcgatttca ttcttttgat aagccatata aaatgcccca
     9121 ttgatataga cgccgtcagc acgtcgttca atagtgtcta cacttccatc tggattgaca
     9181 acctcaagaa cttcatcgct taaaatattt acttgcgtat ctccgaaccg cactgatgag
     9241 ccattctcaa actgagcctc accagataca actttagagt ttgccgataa gctatcatca
     9301 gcaaaaacaa acaagcgacg gggaaatgct agacatacag aaaacagaca taactagcaa
     9361 acacatgcat ttaaacatct tagacataac ggaaactcct ttgtattttt gatttttttc
     9421 aacttttatt atacaataaa accaaataaa aagaaagcgg taacaatatg cttaatgcga
     9481 aaatttttta tatattttta tgtttgatcg ttatcgaaac tacaggcttg ttgttgttga
     9541 aaagaggtct cgaaatgggt tatttagaca cagaagctat tatcctcgca gttttttcat
     9601 ttgcttttta caacctatgt tcattcgctt gggtctgctc tacaataaaa aacaataaaa
     9661 aataaataga cgtattttca aaaaaaaaaa tgcatattta tcttatcgaa acgacgattt
     9721 aaatcgtcgt ttttttgtag tacgacgggc atgtcgtata tctgaggtgt aagtcctcgg
     9781 tgggcacctg ctaccggtga acccaatagc gattcccaag cctgactatc gtgaggtagc
     9841 agggagagga agggatagcg aaatcgtggc tctacgaaca ggaacgtgat agtaaggcgt
     9901 atatagcgga taaggaggct tcaaactcta aagtccaaaa aggtagtcgt aacctatatg
     9961 tgtaaatcac gagagtaatt gaattcggac taaggtttgt gtgaaaaaga taaatctttc
    10021 tagagtctaa agactctgcg tcagatttcc tattttcact gtaacctttt aacgtcctca
    10081 tatcttgtat acacgaggaa agatgtacga cttatcccgt gaggtttcat gagcgctgaa
    10141 agcgtagtaa caacgaatca tgagaagtca gccgagccca tagtagtgag gaaacttctg
    10201 tagtggaagt ggagcgaagg ggtgaatact caaacagtct ggggagagac tgtttgaggt
    10261 ctgtcgctag aaagagaaaa cgacagatcg aagtaatcct acttcacttg tgtctgtaaa
    10321 atgagtggtc tgatagaact ggactttgac acgtaatgac tagatgaagg ttcaccaata
    10381 taagatgtcc ctcaggcacc aaaacaagaa aggaatacgc acatgtcaaa actgctagat
    10441 aagatattat cacgcgaaaa tatgctggaa gcctacaatc aagtaaaatc caataaaggc
    10501 tcagctggga ttgatggaat gactatcgaa gagatggata attatctcag acaaaactgg
    10561 cgcttgacta aggaactgat aaaacagaga aaatataagc ctcaaccagt tcttaaagtt
    10621 gagataccta aaccagacgg aggcatccgt caactaggaa ttccaacagt tatggataga
    10681 atgattcaac aggccattgt ccaagtcatg agccccattt gtgaacccca tttctcagat
    10741 acgagttatg gtttcagacc aaataggtca tgtgaaaaag ccatcatgaa gctcttagaa
    10801 tacttaaatg acggctatga gtggatagtg gattagacct agagaaattt ttcgatacag
    10861 ttcctcaaga tagattgatg tccttagtac ataacattat cgaagacgga gatacggaat
    10921 ccttgattcg taagtatctt cattcaggtg ttatcattaa tggtcaacgt tataaaacac
    10981 tagttggtac accacaggga ggaaatttat ctcctctctt atccaatatc atgcttaatg
    11041 aattggacaa ggaattagaa aagaggggac ttcgatttgt gcgctacgca gatgattgtg
    11101 tgattacggt cggaagcgag gcagcctcta agcgtgtgat gtattcagtc agtcgtttta
    11161 ttgagaaacg gctaggtttg aaagtaaaca tgaccaagac taagattacc agaccaagag
    11221 agttgaaata tctaggtttt gggttctgga aatcatcaga tggttggaaa agccgtccac
    11281 atcaagatag tgttcggaga tttaagctta aattgaagaa actaacacat aggaaatgga
    11341 gtatagacct aacaagacgt attgagcaac tgaatttgtc tattcgagga tggataaact
    11401 atttctcatt gggaaatatg aaagtatagt cgccagcata gatgagcgct tgcgtactcg
    11461 cctacgagtg attatctgga agcaatggaa gaagaaatcg agacgattat ggggattgct
    11521 taagt
//
LOCUS       DAVHTH010000058        11298 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.058, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000058 DAVHTH010000000
VERSION     DAVHTH010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11298)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11298)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11298
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.058"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            complement(<1..772)
                     /locus_tag="VVR63_001722"
     CDS             complement(<1..772)
                     /locus_tag="VVR63_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEU6129715.1"
                     /translation="MTKTLKRPEVLSPAGTLEKLKVAVQYGADAVFIGGQAYGLRSRA
                     GNFTFEQMEEGVQFAAKYGAKVYVAANMVMHEGNEAGAGEWFRKLRDIGIAAVIVSDP
                     ALIMIAATEAPGLEIHLSTQASATNYETLEFWKELGLTRVVLAREVSMEELAEIRKRT
                     DVEIEAFVHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYDLYDMPFGKERKSL
                     QGEIPEEFSMSAVDMSMIDHIPDMIENGVDSLKIEGRMK"
     gene            1396..1578
                     /locus_tag="VVR63_001723"
     CDS             1396..1578
                     /locus_tag="VVR63_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001262531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HEU6129716.1"
                     /translation="MANDNKSHYLIYRVLGISFEEGENIDLYQNKGRFLYKYAGSFLE
                     EAAVLSFNEKFGTENT"
     gene            1588..1953
                     /locus_tag="VVR63_001724"
     CDS             1588..1953
                     /locus_tag="VVR63_001724"
                     /inference="COORDINATES: protein motif:HMM:NF021048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HEU6129717.1"
                     /translation="MPNSENTKPKTFEIDCLVGEKHAYEIKWWDATTDGDHITKEHTR
                     IKVIHNKGYIPIRLMFYYPNRTQAIKIQQTLETLYNGIGGKYYYGDSAWEHLRAVTGI
                     DLLSILTDIANKKTGVKSK"
     gene            1950..3140
                     /locus_tag="VVR63_001725"
     CDS             1950..3140
                     /locus_tag="VVR63_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HEU6129718.1"
                     /translation="MTVLKGDNLEILKTIESSSIDLIYMDPPFFTQKTQKLSNNKNIM
                     YSFEDTWTSIEDYKEFLSVRLEECKRVLKNSGSIFVHCDKIANHHIRLILDNIFGADM
                     FQSEIIWNYKRWSNSKKGLLNNHQNIYFYSKSKDFKFNTIFTEYSSTTNIDQILVERK
                     RDGNSKTIYKVDNNGNYILAKEKNGVPLSDVWNIPFLNPKAKERVGYPTQKPILLLEQ
                     IIKIATDKNDIVLDPFCGSGTTLVASKILNRNYMGIDLSEEAINITQQRLENVIKTSS
                     NLLNKGIEAYRTKTEEEENILKLLQAKIVQRNKGIDGFLPKHFQKKPIPIKIQKNNEC
                     LNESISLLQNAINSKKLDFGVVIKTHSDNLLFDFDTIPENIIVVDHFELTIEKWLSKS
                     QQLL"
     gene            complement(3649..4641)
                     /locus_tag="VVR63_001726"
     CDS             complement(3649..4641)
                     /locus_tag="VVR63_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU6129719.1"
                     /translation="MSYYDFVKDYMKVDECKNNEKYSSAGHTFCWKKENSTYAEGLYW
                     FYEGGSFIIDIHDFYIKEEVVQNSTYSMSDYVSIYSSYIVSANGEKFNPYQTITANSL
                     CTFDFDNIKDDFVFLLHENCCYLAVSIGFKKELIEKHLASININPESFYSTLLQPNQI
                     ILTKALERVAMEILNCKMDAPAADFFFKAKANEWISIVIDTYLNRKKYKIEIDDDKAL
                     EDVARFLDDHFATNVNQGTLEKISKMSGTKLKNLFKEKYCQSITEYTQRKRMNVAETL
                     LLNTELPIKEIAESVGYSSASKFSIYYKRYKGKLPSEVRNLACKHHNFKCDYCD"
     gene            4801..6555
                     /locus_tag="VVR63_001727"
     CDS             4801..6555
                     /locus_tag="VVR63_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6129720.1"
                     /translation="MKIYKKLFAYVQDKKYLGVLAIIFSAISALLTVYGYYLIYKFLD
                     KLIINSNLSGAESIALKSVITLTSGAIFYFVSGMFSHILGFRLETNLRKRGIDGLEKA
                     SFRFFDLNPSGQIRKIIDDNAAQTHQVVAHMIPDSSQAIITPVLVLALGFIVSIRVGI
                     ILLALTIIGGLILGAMMGEQEFMKIYQESLSKLSAETVEYVRGMQVVKIFKANVESFK
                     SFYKAIKDYSKYAYDYSLSCKRPYVLYQWLFFGLIAILIIPIVYFMTSLASAKVILLE
                     LIMILFLSGVLFVSFMRMMWYSMYISQGNYAVDTLEALYEDMQKDKLVHGNVNNFKNY
                     NIEFENVSFAYNDKAVIENLSFNLEEGKSYALVGSSGSGKSTVAKLISGFYNVNKGSI
                     KIGGIAISEYSDEALIKAISFVFQDSKLFKKSIYDNVALANKDATKDDVMRALKLAGC
                     DLILDKFPERENTIIGSKGVYLSGGEKQRIAIARAILKDSKIIIMDEASASIDPDNEF
                     ELQKAFKNLMKDKTVIMIAHRLSTIKDLDEIIVMDSGKIIERGSDKELMSKDTRYKSL
                     QEMFNSANEWRVSNERVL"
     gene            6539..8260
                     /locus_tag="VVR63_001728"
     CDS             6539..8260
                     /locus_tag="VVR63_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019214631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6129721.1"
                     /translation="MKEFYKKRFALTDGGARNLSKATLASFFVYCINMLPAILLMIFA
                     QEVLENMGKSNGFYIVFSVLTLIAMYILLSIEYDKLYNTTYQESADLRIRTAENLSKL
                     PLSYFSKHDISDISQTIMADIEGIEHAMSHSIPKVGGMVLFFPLISVMMLAGNVKMGL
                     AVIIPSILSFIFIPLSKKYQVNGQNRYYDVLRKNSESFQENIEMQMEIKAYNLSKDIK
                     DDLYKKMEDSERVHLKAEVTTILTLSISSIFSFISLAVVIFVGVNLIINKEINSLYLI
                     GYLLAAMKIKDSLDASKEGLMEIFYLSPKIERLKEIQNQDLQEGDDYSLKKFDIDLKD
                     VEFAYNKDAKVLNGVSFKAKQGEVTALVGASGCGKTTILKLISRLYDYDKGQILIDGK
                     DIKEISTESLFDKVSIVFQDVVLFNQSIMENIRIGKQDASDEEVKRAAKLANCTDFIE
                     KMDKGFDTVIGENGAELSGGERQRLSIARAFLKDAPILILDEITASLDVNNEKKIQES
                     LNNLVKDKTVVIISHRMKSIENADKIVVLQNGRVESEGKHEELLQKSKIYKNLIEKTK
                     MAEEFIY"
     gene            8271..8855
                     /locus_tag="VVR63_001729"
     CDS             8271..8855
                     /locus_tag="VVR63_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000368966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEU6129722.1"
                     /translation="MDNKKLKVKDLVSIGVFGVIYFAFMFGVGMMGLIPILFLIYPTV
                     LAIVAGTVVMLFMAKVQKPWALFIFGMISPLVMFAAGHTYVVVVLSLIVMIIAELIRK
                     IGNYNSFKYNMLSYAIFSTWICSSLMQMLLAKEKYMEWSLMTMGKDYVDVLEKLITYP
                     HMALVALGAFLGGILGAYIGKALLKKHFEKAGIV"
     gene            8855..9550
                     /locus_tag="VVR63_001730"
     CDS             8855..9550
                     /locus_tag="VVR63_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEU6129723.1"
                     /translation="MSTFSSNAPFNPNPISKILVVFITGLTVMHSINIRFELAIVCLI
                     GILLYLNGYKKTLFKWIILCGILYSLPNFMVLSELNPIVKMFLSIPIVIRMFILPFMA
                     ASFMIKTSDVGAIISSMDKLKISKNVSIPIAVMFRFFPSFKEEKKNIKMAMRVRGISF
                     KNPVKYLEYVSMPLLIISSNISDDIAKAAETKAIENPIAKTRYIRVKIQLIDFVYVLA
                     VAGLIVGGLIWLK"
     gene            9538..10902
                     /locus_tag="VVR63_001731"
     CDS             9538..10902
                     /locus_tag="VVR63_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002837029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6129724.1"
                     /translation="MVEIKNLSLDYGEEHILDDISLSIAEGECVLFTGKSGNGKSSLI
                     NSINGLAVRYDNAKTKGEIIIDGKNIKNLELYQISMLVSTVFQNPKTYFFNVNTTLEL
                     LFYLENIGLAREEMDRRLKDMLKIFPIKNLLNRNIFNLSGGEKQILCIAASYIAGTKI
                     IVMDEPSSNLDIKSISVLAKMLKILKEKGISIIVAEHRIYYLMDIVDRVFLIDKGKLK
                     KTYTRSEFLKLDKNELNALSLRDKELSKLKVPYLKEGGEYQIKNLSYKFTDDECLSLK
                     DISFKLGKIYGIIGSNERGKSTLLRCLIGLEKKSKEEIYFKGEKLSKKERLKNSSLVM
                     QDVNHQLFTDEVFNELRLGVKNFDEEKAKIILKDLGLDEFIERHPMSLSGGQKQRLAI
                     ASVMCKNSPFIFFDEPSSGMDYSNMIKISELINKYKTMDKIIFIVSHDIEFLNEVADE
                     IFEL"
BASE COUNT         4134 a         1597 c         1911 g         3656 t
ORIGIN      
        1 acttcatacg tccttcgatt tttagactgt ccacaccatt ttcaatcata tctggaatgt
       61 ggtcaatcat agacatgtca acggctgaca ttgaaaattc ttctggaatc tcaccctgca
      121 aactcttacg ttctttccca aatggcatat cgtaaaggtc gtatttccaa cggcatgact
      181 gagaacatcc accacggttg gcatcacgca tactcatgtg gtttgaaaga gtacaacgtc
      241 cagagtatga aatacacata gctccatgga caaaggcttc aatttcaaca tctgtacgtt
      301 tgcggatctc agctaattct tccattgaaa cctcacgcgc taaaacgaca cgagtcaagc
      361 ctagctcttt ccagaactca agggtttcat agttagtggc actggcttgg gtagaaaggt
      421 ggatttcaag gcctggtgct tcagtcgctg caatcataat caaggctggg tcagatacga
      481 taactgctgc aatcccgata tcacgcagtt tacggaacca ctcaccagca ccagcttcat
      541 ttccttcgtg cataaccata ttagccgcta catagacctt ggcaccatac ttggccgcaa
      601 actgcacgcc ttcttccatc tgttcgaaag taaagtttcc cgcacggcta cgaagaccat
      661 aggcctgacc accgataaag acagcatctg ctccatactg aacagctacc tttagcttct
      721 ctaaagtccc tgcaggtgat aaaacctcag gacgttttaa tgtttttgtc atgatttctc
      781 ctatttgcaa tataaaagtt tgacattttt ccttctcatt ttatagtaaa taaaggataa
      841 aatcaagcct agacggattg ttttgacaat tctaatcttt tagactttgc ataataactg
      901 ttaaacagtc gaaaattacc ccagttttaa caagtagtca aaaagtctaa aaaagtaaaa
      961 accagtatcc caagatactg actcgtaaaa atacataaat tagtccttag atgactactc
     1021 ccactctgtt gctcctataa tggaaaagga ttgatacagt ctagaatatc gcttttttat
     1081 ttattattct gatataaaac tgttagaatt gattttttgt tttataccca aatatgaata
     1141 gagacgtagc taataagttg aataacatat ttggaaaaat gagaaatagc aatattacta
     1201 gaacttttag aaacaatcaa tatttaaaaa gaaaaaagct caaagaattt attaaaccat
     1261 gttataatag atatagctat aattttattt ataacaagag gatagaaatg accgaattag
     1321 aaagaaaaaa tcgaaaaatt agctaagaaa tattctgata acttaaacat caaagttcaa
     1381 gagagagttc gtgaaatggc aaatgataat aagagccatt atttgatata cagagtttta
     1441 ggtatttcat ttgaagaagg agaaaatatc gatttgtatc aaaataaagg tcgtttttta
     1501 tacaaatatg ctggttcatt tttagaagaa gctgcagtac tatcctttaa cgaaaaattt
     1561 ggtacagaaa atacttaaaa agttaacatt cctaattctg aaaatacaaa acctaagact
     1621 tttgaaattg attgtttagt cggagaaaaa cacgcatacg aaataaaatg gtgggatgca
     1681 actacagatg gagaccatat aactaaagaa cacactagaa taaaagttat tcataacaaa
     1741 ggatatatac caattcggtt aatgttctac tatccaaata gaactcaagc tataaaaatt
     1801 cagcaaactt tagaaacatt gtataacggt attggaggga aatattatta tggagattct
     1861 gcctgggaac atttaagagc agtgaccggt attgatttac ttagtattct aacagatatt
     1921 gcaaataaaa aaacaggggt aaaatcaaaa tgacagtatt aaaaggagat aacttagaaa
     1981 tattaaaaac tattgaatcc tcaagtattg atttaatcta tatggaccct cctttcttta
     2041 cacagaaaac ccaaaaatta tctaataaca aaaatattat gtattcattc gaagatacgt
     2101 ggacttcgat tgaggattac aaagaatttt tgtctgtaag attagaagaa tgcaaaagag
     2161 tgctaaaaaa tagtggcagt attttcgttc attgtgataa aattgcaaat catcatatta
     2221 gattaatttt agataatatc tttggagcag atatgtttca aagcgaaatt atatggaact
     2281 ataaacggtg gtctaattca aaaaagggat tattgaacaa tcatcaaaac atttactttt
     2341 attcaaagtc aaaagatttt aaatttaata caatttttac agagtattct tctactacaa
     2401 atatcgacca aatactagtg gaacgaaaac gagatggaaa ctctaaaact atatataagg
     2461 ttgataataa tggtaactat attctagcaa aagagaaaaa tggagttccc ctttcagatg
     2521 tttggaatat accatttctt aatccaaaag ctaaagaaag agtaggttat cctacacaaa
     2581 aacctattct gttattagaa caaattataa agattgctac tgataaaaat gatatagttt
     2641 tagacccgtt ctgtggaagt ggaactactt tagtagcctc caagattttg aatagaaatt
     2701 atatggggat tgatttatct gaggaagcta tcaatataac tcagcaacgt ctggaaaatg
     2761 ttataaaaac aagttcaaat ttattgaata aaggaatcga agcatataga accaaaactg
     2821 aggaagagga aaacattctt aaattattac aggcaaaaat tgttcaaaga aataaaggaa
     2881 ttgatggttt tttacctaaa cattttcaaa aaaaaccgat acctataaaa attcaaaaaa
     2941 ataatgaatg tctgaatgag agtatctctt tattacagaa tgctataaac tccaaaaaac
     3001 ttgattttgg agtagttata aaaactcatt cagataattt attatttgat tttgatacga
     3061 ttcctgaaaa tataatagta gttgaccatt ttgaacttac aatcgaaaaa tggttaagta
     3121 aaagtcaaca gttactatag tttgcaaatt atttacagaa agaacaaaaa atgctctgaa
     3181 acactgattt caaggcattt tttgttagtt taaaattact cccattcttc ttttccaaac
     3241 gtacaatata tccaaaacca ttcaaaatac tagattctat tttttataat atcactaaat
     3301 ccacctaatt ataggacgtt ttcagatttt tagtcccgtc ccagtaccgg agaaatattg
     3361 ttttaatata atatctcttt ttgtcttcta agctcttaaa agcaaaagaa caagtaaaga
     3421 gtcaagacaa ggataaaaag tccatattag ggcaaataaa aagctttaag acagatgaca
     3481 aatctaagtc aaataagaaa gaccatagca aaggtgcaga gagataaata ttggcggtct
     3541 tcggactgcc tttatttttt tatccatttt tcaaatcaaa tttattcaga ctatatatgc
     3601 acatatacac ttaaattcat ataaaaacat ggcttgtaaa aaattacttt aatcacaata
     3661 atcgcattta aaattgtgat gtttgcaagc taaattacgg acttcacttg gaagttttcc
     3721 cttgtatctt ttataataga tagaaaattt gctggcagat gaatatccaa cagattctgc
     3781 tatctctttt ataggtagtt cagtgtttaa aagaagagtt tcagctacat tcattctttt
     3841 tctttgagtg tactctgtaa tgctttgaca atatttttcc ttaaataaat tttttaattt
     3901 agtaccactc attttagata ttttttcaag cgtgccttga tttacattcg ttgcaaaatg
     3961 atcatctaag aatcttgcta catcttcaag tgctttatca tcatcaattt caattttata
     4021 tttttttcta tttaagtatg tgtcaattac tatacttatc cattcatttg cctttgcttt
     4081 aaagaaaaaa tcagcggcag gagcgtccat cttacaattt aatatttcca ttgccactct
     4141 ttctaaggcc tttgtaagta ttatttgatt cggttgaagc aaggttgaat aaaaagattc
     4201 tggattaatg ttaatagatg ctaaatgttt ttctattagc tcttttttaa aaccaatgga
     4261 aacagcaaga taacaacaat tctcgtgtaa taaaaaaaca aaatcatctt ttatattatc
     4321 aaaatcaaaa gtacataaag agtttgcggt aatagtttga tacggattaa acttttctcc
     4381 gtttgcactg acaatgtaac ttgaataaat tgaaacatag tctgacatac tataagtgct
     4441 attttgaact acttcctctt tgatataaaa atcatgtata tcgataatga agctgcctcc
     4501 ttcataaaac caatataggc cttctgcata agttgaattc tcttttttcc aacaaaatgt
     4561 atgacctgca cttgaatact tctcattgtt tttacattca tctactttca tataatcttt
     4621 tacaaaatca taatatgaca taacacacta tcccttttag acaatattcc aattagcctt
     4681 attaattcaa aactattgta ttagtaatta taacagatgt ataatagaaa agcaatgata
     4741 gatattatca attaagcgaa tttatatcta aaagggatat taaagaaagg agatatgctt
     4801 atgaagattt acaaaaaact atttgcttat gtccaagata agaaatatct tggggttttg
     4861 gccataattt tttctgctat atctgctcta cttacagtat atggatatta tttaatctac
     4921 aaatttctag ataagttaat aattaattca aacttatccg gtgcagagag tatagcatta
     4981 aaatctgtta ttacactaac aagtggagcg atattttatt ttgtctcagg aatgttttca
     5041 catatcttgg gatttaggct tgaaacaaat ttaagaaaaa ggggaatcga tggtctggaa
     5101 aaagcaagtt ttaggttctt tgacttaaat ccatctggtc aaataagaaa gatcatagat
     5161 gataatgcag cacaaactca tcaggtggta gcacacatga ttcccgatag ttctcaggca
     5221 ataatcacac ccgtacttgt acttgcactt ggctttatag taagtataag ggttggcata
     5281 attttgcttg ctcttactat aattggtggc ttaattttag gggcaatgat gggcgagcaa
     5341 gaatttatga agatatacca agaatcccta tctaaactaa gtgctgaaac tgttgagtac
     5401 gtgagaggaa tgcaagttgt aaaaatattt aaagcaaatg tagagtcttt taaaagcttt
     5461 tataaggcga taaaagatta ctcaaagtat gcttatgatt attccctatc ttgtaaaagg
     5521 ccttatgttt tgtatcaatg gttatttttt ggactgattg caattttaat tattcctata
     5581 gtttatttta tgactagctt agctagcgca aaggtgattt tacttgagct tatcatgatt
     5641 ttatttttat caggagttct ctttgtttca ttcatgagaa tgatgtggta ctccatgtat
     5701 atttctcaag gaaattatgc agtagatact ttagaggcgc tttacgaaga tatgcaaaaa
     5761 gacaaattag tgcatggtaa tgtcaataat tttaaaaact ataatataga atttgagaat
     5821 gttagctttg cttataatga taaagctgtc attgaaaatt tatcctttaa tttagaagaa
     5881 ggaaagtcct acgcacttgt cggttcatct ggatcaggca aatcaacagt agcaaaactt
     5941 atatcaggtt tttacaatgt taataaagga agcataaaga taggcgggat agcaataagt
     6001 gaatattctg acgaagcctt aattaaagcc atttcctttg tttttcaaga ttcaaaatta
     6061 ttcaagaaga gcatttatga taatgtagct ttagctaata aagatgcgac gaaagatgac
     6121 gttatgagag ccttaaaatt agcaggatgc gatttaatat tagacaaatt cccagaaaga
     6181 gaaaatacaa tcataggctc aaaaggtgtt tatttatccg gtggagaaaa acaaagaatt
     6241 gcaattgcta gagcaatttt aaaggattcc aaaattatta ttatggatga agcatcagca
     6301 tctattgacc cagataacga gtttgaattg caaaaagctt ttaaaaatct tatgaaggat
     6361 aaaacagtta tcatgattgc acacaggcta tctacaatta aagaccttga tgaaattatt
     6421 gtcatggata gtggaaaaat tatagaaaga gggtctgaca aagaattaat gtcaaaagat
     6481 acaaggtata agagcctgca agagatgttt aacagtgcga atgaatggag ggtttcaaat
     6541 gaaagagttt tataaaaaaa gatttgctct tacagatgga ggagcaagaa atttaagtaa
     6601 agcaacactg gcttcatttt tcgtttattg tataaacatg cttcctgcca tattacttat
     6661 gatttttgct caggaagttt tggaaaatat gggcaaaagc aatggctttt atatagtatt
     6721 ctcagttttg actttgatag caatgtatat tttgctttct atcgaatacg ataaattata
     6781 taacacaacc tatcaagaaa gtgcagattt aagaataagg acagcggaga atttatcaaa
     6841 attacctcta tcttactttt ctaaacatga catttccgac atttcacaaa caatcatggc
     6901 tgatattgaa ggcatagagc atgcaatgag ccactcaata ccaaaggtgg gcggcatggt
     6961 actgtttttc ccattaatat ctgtaatgat gctagcgggc aatgtcaaga tgggtttagc
     7021 tgtaattatt ccatctattt taagctttat atttatacct ttatctaaaa aatatcaggt
     7081 taatggacag aatagatatt atgatgtctt aagaaaaaac tcagaaagct ttcaagaaaa
     7141 tatcgaaatg caaatggaga ttaaagcata taatttatcg aaggatatta aagatgactt
     7201 atataaaaaa atggaagata gtgagagagt acacttaaag gcagaagtaa ctacaatttt
     7261 aactttgtct atatcttcaa tatttagctt tatatctctt gctgttgtga tatttgtcgg
     7321 cgtaaatcta attattaata aagagataaa ttctctctac cttataggat atttactagc
     7381 tgctatgaag ataaaagact ctttagatgc atctaaagag ggcttgatgg aaatatttta
     7441 tttatcgccc aaaatagaaa gattaaaaga aattcaaaat caagatttac aagaaggcga
     7501 tgactatagc ttaaaaaaat ttgatattga tctaaaagat gttgagtttg cctacaataa
     7561 agacgcaaaa gttttaaatg gtgtaagttt taaagctaag cagggagagg tcactgcttt
     7621 ggtaggtgca agtggctgcg gtaaaacaac tatcttgaaa cttatatcaa gactttatga
     7681 ttatgacaag ggacaaatct taatcgatgg caaagatata aaagaaatat caacagaatc
     7741 tctttttgat aaggtctcta tagttttcca agatgtggtt ctctttaatc aaagcattat
     7801 ggaaaatatt agaatcggaa agcaagatgc aagtgacgaa gaggttaaaa gagcagcaaa
     7861 acttgcaaat tgcacagatt ttatagaaaa aatggataaa ggtttcgata cagttattgg
     7921 tgagaacgga gctgagctat caggaggaga aagacaaaga ttatcaatag ccagagcctt
     7981 cttaaaagat gcgccgatat tgatcttaga tgagataaca gcaagccttg atgttaacaa
     8041 cgagaaaaag attcaagagt ctttaaataa tttagttaaa gataaaactg ttgtaatcat
     8101 ttcacataga atgaaatcca tagaaaatgc agacaagata gtagttcttc aaaacggaag
     8161 agtagaaagc gaaggtaagc atgaagagct tttacaaaaa tcaaaaattt acaaaaattt
     8221 aatagaaaag acaaaaatgg cagaagaatt tatttattag gaggactaca atggataata
     8281 aaaaattaaa agtaaaagat ttagtaagta tcggtgtttt tggcgtaatt tattttgcct
     8341 tcatgtttgg agttggtatg atgggcttga ttccaatatt gttcttaata tacccgacag
     8401 tattagccat agttgcagga actgttgtta tgttatttat ggctaaggtt caaaagccat
     8461 gggcactatt tatatttggt atgatatcac cacttgtgat gtttgcagct ggtcatacct
     8521 acgtagttgt ggttttatca cttatagtaa tgataatagc agaattaatt agaaagattg
     8581 gtaattataa ttcatttaaa tacaatatgc tttcttatgc aatcttcagc acatggatat
     8641 gtagctcttt aatgcaaatg cttttagcaa aagaaaaata tatggagtgg tctttgatga
     8701 cgatgggaaa agattatgtt gatgtattag aaaagttaat aacttatcct cacatggctt
     8761 tagtagcctt aggtgctttc ttaggaggaa ttcttggagc atatataggc aaggctctat
     8821 tgaaaaaaca ctttgaaaaa gcaggcattg tataatgtct actttttctt caaatgctcc
     8881 ctttaatccc aatccgatct ctaagatatt agtcgtattt atcacaggct taactgttat
     8941 gcatagcata aacatccgtt ttgagctggc aattgtttgt cttattggta ttttgcttta
     9001 tttgaatgga tacaaaaaaa cacttttcaa atggattata ttgtgtggga tactttactc
     9061 cttgcctaat tttatggtgt tatctgaatt aaaccctata gttaagatgt ttttgagtat
     9121 acctattgtt attagaatgt ttattttacc atttatggca gcaagcttta tgataaagac
     9181 ctcggatgta ggcgcaataa tttcatcgat ggataagctt aagatttcaa agaatgtatc
     9241 catacctatt gcggttatgt ttagattctt cccatctttt aaggaggaga agaaaaacat
     9301 caaaatggct atgagagtaa gagggataag ttttaaaaac ccagtcaaat atcttgaata
     9361 tgtttctatg ccactactca ttatatcatc taatatatca gatgacattg caaaagcggc
     9421 agaaacaaag gcaatagaaa atccaattgc caagaccaga tacattcgcg taaagataca
     9481 gctaattgat tttgtttatg ttttagcggt tgctggactt attgtgggag gcttaatatg
     9541 gttgaaataa aaaatttaag tcttgattat ggtgaagagc atatattaga tgatatatca
     9601 ctatccatag ccgagggaga gtgcgtgcta tttacaggaa aaagtggaaa tggtaagtca
     9661 tctttaataa attcaatcaa tggactagct gtaaggtatg ataacgcaaa gacaaagggc
     9721 gaaataatta ttgatggtaa gaatataaaa aatttggaac tttatcaaat ctcaatgctt
     9781 gtttcaactg tttttcaaaa tcctaagaca tattttttta atgtcaatac gacattagaa
     9841 ttattatttt atttggaaaa tatcggtctt gcaagagaag agatggacag gcgtttgaag
     9901 gatatgctta agatattccc gataaaaaat cttttgaaca gaaatatatt taatctatcc
     9961 ggcggtgaaa aacaaattct ttgcattgca gcttcttata tagcaggtac aaagattata
    10021 gttatggatg agccttcatc gaatttagat attaaaagca taagtgtttt ggcaaagatg
    10081 ctaaagatat taaaagagaa aggcataagc ataattgttg cagagcatag aatttattat
    10141 ttgatggaca tagttgaccg tgtattttta atagataaag gaaagcttaa aaaaacttat
    10201 actagaagtg aatttttaaa gctagataaa aatgaattaa atgctttaag tttaagagat
    10261 aaagaattaa gtaaattaaa agttccttat ttaaaagaag gtggagagta tcagataaaa
    10321 aatcttagct acaaatttac tgatgatgag tgtttaagct taaaagatat ttcattcaag
    10381 cttgggaaaa tttatggcat aataggatcc aacgaacgag gaaaatcaac gcttttaaga
    10441 tgtttaatag gtcttgagaa aaaatcaaaa gaagaaattt attttaaggg agagaagcta
    10501 tctaaaaaag aaagactcaa aaactcttca cttgttatgc aagatgtaaa tcatcaatta
    10561 ttcacagatg aagtattcaa cgagcttaga ttaggagtaa agaattttga tgaagaaaag
    10621 gcgaaaatca ttttaaaaga tttaggcctg gacgaattta ttgaaaggca tccgatgagt
    10681 ttatcaggag ggcaaaagca aaggcttgca atagcatctg ttatgtgcaa gaattctcca
    10741 tttatctttt ttgacgaacc ttcaagtggt atggattatt ccaatatgat aaaaatatct
    10801 gaactgatta ataagtataa aaccatggat aaaataattt ttattgtttc ccatgatata
    10861 gaatttttaa atgaagtggc agatgaaatt tttgaattgt aaaatagagt ctgttaaaca
    10921 tgtctataga actagtaaat tgtctaaaaa tttaaaagat actaacacat attgatattt
    10981 atagaaaatt aacttcagga tttttacagt atttataaac tttataatat gtatttatag
    11041 tattaataat ttccatatct ttagggaaat tatttattta cttaccataa ttaaagagat
    11101 gagagataaa tatcggcagt cttcggactg cctttatttt tttacttaat ttaatgcagt
    11161 aaatcatacg attgaaagga atctgcgtta tatgctataa ttaggtagtt aatctataca
    11221 tttagaaagg taaaatatag aattggagaa tgatatggga ttttcatata ataaattgta
    11281 accgcccaat aacgaagt
//
LOCUS       DAVHTH010000059        10633 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.059, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000059 DAVHTH010000000
VERSION     DAVHTH010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10633)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10633)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10633
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.059"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            complement(<1..1416)
                     /locus_tag="VVR63_001732"
     CDS             complement(<1..1416)
                     /locus_tag="VVR63_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HEU6129725.1"
                     /translation="MTRYQNLVNGKWKSSEQEITIYSPINQEELGTVPAMTQTEADEA
                     MQAARAALPAWRALSAVERAAYLHKTAAILERDKEEIGTILAKEVAKGIKAAIGEVVR
                     TADLIRYAAEEGLRITGQAMEGGGFEAASKNKLAVVRREPVGIVLAIAPFNYPVNLSA
                     SKIAPALIAGNVVMFKPPTQGSISGLLLAKAFEEAGIPAGVFNTITGRGSEIGDYIIE
                     HKEVNFINFTGSTPIGERIGRLAGMRPIMLELGGKDAALVLEDADLEHAAKQIVAGAF
                     SYSGQRCTAIKRVIVLESVADKLATLLQEEVSKLTVGDPFDNADITPVIDNASADFIW
                     GLIEDAQEKEAQALTPIKREGNLLWPVLFDQVTKDMKVAWEEPFGPVLPIIRVASVEE
                     AIAFANESEFGLQSSVFTNDFKKAFEIAEKLEVGTVHINNKTQRGPDNFPFLGVKGSG
                     AGVQGIKYSIEAMTNVKSIVFD"
     gene            complement(1961..4240)
                     /gene="pulA"
                     /locus_tag="VVR63_001733"
     CDS             complement(1961..4240)
                     /gene="pulA"
                     /locus_tag="VVR63_001733"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HEU6129726.1"
                     /translation="MYNYPMRIHYHRKNGEYDTCSFVKSQDQRIDLLTYKEDYFGALF
                     SFEHPSSHVIESLNFVVHTGQTSKEYSIRFNHYPLLTEVWILEGDDRIYYSENPAIAS
                     PFYKNQNPFAFDKAINSASFDHHWGYQGELGCRVEDNQAHFSLWSPTATEVQVVVYES
                     AANDAPVWKTFEMKRGNSYSYNHKDNTIGVWSLDVEEDLVGKAYQYQVQFPHHQTLTR
                     DPYTIATSPDGKRSAILSHVEKQVENFEVKHGSEATWRLENPCKAVICEMHIRDLTKS
                     PTSGVDEHLRGTFLGAAQAGTVNQYGQSTAFDYIKKLGYNYVQLQPIADRHKEYDEDG
                     NVTYNWGYDPQNYNAPETSFSTNPDDPAQVIRDLKVMVQAYHDAGIGVIMDVVYNHTF
                     SVVDAPFQTTVPDYYYRMNPDGTFQNGTGVGNETASEHEMFRKYMIDSLLYWVQEYNI
                     DGFRFDLMGIHDVKTMQMIRQSLDEIDSNIILYGEGWDMGTGLAPYDKAKKDNAYQMP
                     NIGFFNDNQRDAVKGGEVYGAIKSGFVSGAATEPILAKAILGSRELGSYTHPNQVLNY
                     VEAHDNYNLHDLLATLHPDQSSEQIMRKVETATAMNLLMQGMAFMEIGQEFGRTKLVA
                     TGENGELTHDDRERAMNSYNAPDSVNQVNWNLINERQDSIEFIRQVIRLKTKTGAFSY
                     SSYDEIYHHVFVHSAIEHSGYLIYEVHGKEHLLVVVNAKSEPYQFENAGNLAMLVTNS
                     RSKEDNVLNDISLAVLSVL"
     gene            complement(4352..6310)
                     /gene="ligA"
                     /locus_tag="VVR63_001734"
     CDS             complement(4352..6310)
                     /gene="ligA"
                     /locus_tag="VVR63_001734"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HEU6129727.1"
                     /translation="MNKRMNELVALLNRYATEYYTSDNPSVADSEYDRLYRELVELET
                     AYPEQVLADSPTHRVGGKVLDGFEKYSHQYPLYSLQDAFSREELDAFDARVRKEVAHP
                     TYICELKIDGLSISLTYEKGILVAGVTRGDGSIGENITENLKRVKDIPLTLPEELDIT
                     VRGECYMPRASFDQVNQVRQENGEPEFANPRNAAAGTLRQLDTAVVAKRNLATFLYQE
                     ASPSTRDSQEKGLKYLEQLGFVVNPKRILAENIDEIWNFIQEVGQERENLPYDIDGVV
                     IKVNDLASQEELGFTVKAPKWAVAYKFPAEEKEAQLLSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRKDDTVIVYKAGDIIPAVLRVVESKRVSEEKLDIP
                     TNCPSCNSDLLHFEDEVALRCINPRCPAQIMEGLIHFASRDAMNITGLGPSIVEKLFA
                     ANLVKDVADIYRLQEEDFLLLEGVKEKSAAKLYQAIQASKENSAEKLLFGLGIRHVGS
                     KVSQLLLQYFHSIENLSQADSEEVASIESLGGVIAKSLQTYFATEGSEILLRELKETG
                     VNLDYKGQTVVADAALSGLTVVLTGKLERLKRSEAKSKLESLGAKVTGSISKKTDLVV
                     VGADAGSKLQKAQELGIQVRDEAWLESL"
     gene            complement(6403..7581)
                     /locus_tag="VVR63_001735"
     CDS             complement(6403..7581)
                     /locus_tag="VVR63_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEU6129728.1"
                     /translation="MNRYAVQLISRGAINKMGNMLYDYGNSVWLASMGTIGQTVLGMY
                     QISELVTSILVNPFGGVISDRFSRRKILMTADLVCGILCLAISFIRNDSWMIGALIVA
                     NIVQAIAFAFSRTANKAIITEVVEKDEIVIYNSRLELVLQVVGVSSPVLSFLVLQFAS
                     LNMTLLLDSLTFFIAFVLVAFLPKEEAKVQEKKAFTGRDIFVDIKDGLHYIWHQQEIF
                     FLLLVASSVNFFFAAFEFLLPFSNQLYGSEGAYASILTMGAIGSIIGALLASKIKANI
                     YNLLILLALTGVGVFMMGLPLPTFLSFSGNLVCELFMTIFNIHFFTQVQTKVESEFLG
                     RVLSTIFTLAILFMPIAKGFMTVLPSVHLSSFLIIGSGVIILSCISFIYVRTHFEKLI
                     "
     gene            complement(7661..8524)
                     /locus_tag="VVR63_001736"
     CDS             complement(7661..8524)
                     /locus_tag="VVR63_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HEU6129729.1"
                     /translation="MEHLGKVFREFRTSGNYSLKEAAGESCSTSQLSRFELGESDLAV
                     SRFFEILDNIHVTIENFMDKARNFHNHEHVSMMAQIIPLYYSNDIAGFQKLQREQLEK
                     SKSSTTSLYFELNWILLQGLICQRDATYDMKQDDLDKVADYLFKTEEWTMYELILFGN
                     LYSFYDVDYVTRIGREVMEREEFYQEISRHKRLVLILALNCYQHCLEHSSFYNANYFE
                     AYTEKIIDKGIKLYERNVFHYLKGFALYQKGQCKEGCKQMQKAMHIFDVLGLPEQVAY
                     YQEHYEKFVKS"
     gene            complement(8527..10428)
                     /locus_tag="VVR63_001737"
     CDS             complement(8527..10428)
                     /locus_tag="VVR63_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEU6129730.1"
                     /translation="MIILQANKIERSFAGEVLFDNINLQVDERDRIALVGKNGAGKST
                     LLKILVGEEEPTSGEINKKKDISLSYLAQDSRFESENTIYDEMLHVFDDLRRTDKQLR
                     QMELEMGEKSGEDLDKLMSDYDRLSENFRQAGGFTYEADIRAILNGFKFDESMWQMKI
                     AELSGGQNTRLALAKMLLEKPNLLVLDEPTNHLDIETISWLENYLVNYSGALIIVSHD
                     RYFLDKVATITLDLTKYSLDRYVGNYSRFVELKEQKLATEAKNYEKQQKEIAALEDFV
                     NRNLVRASTTKRAQSRRKQLEKMERLDKPEAGKKAANMTFQSEKTSGNVVLTVENTAI
                     GYDGEVLSQPINLDLRKMNAVAIVGPNGIGKSTFIKSIVDQIPFIKGEKRFGANVEVG
                     YYDQTQSKLTPSNTVLDELWNDFKLTPEVEIRNRLGAFLFSGDDVKKSVGMLSGGEKA
                     RLLLAKLSMENNNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRVAT
                     HVLELSENGSTLYLGDYDYYVEKKATAEMSQTEEASTSNQVKEASPVNDYQAQKESQK
                     EVRKLMRQIESLEAEIEELESQSQAISEQMLETNDADKLMELQAELDKISHRQEEAML
                     EWEELSDQV"
BASE COUNT         3191 a         2350 c         1898 g         3194 t
ORIGIN      
        1 atcaaaaaca atggatttga catttgtcat cgcttcaatg ctatatttaa ttccttgcac
       61 tccagctcca gaacctttga caccaaggaa tgggaaatta tctggaccac gctgggtttt
      121 attattaatg tggactgtac ctacttcaag tttttcagca atttcaaagg cttttttgaa
      181 atcatttgta aagactgatg attgaaggcc gaattcagat tcgttggcaa aggcaatagc
      241 ttcctctaca ctagccacac gaatgattgg taaaacagga ccaaatggct cttcccatgc
      301 cactttcata tcttttgtaa cttggtcaaa aagcactggc cagagaagat tgccctcacg
      361 tttgattggt gtaagagcct gagcttcttt ttcttgtgca tcctcaatca agccccaaat
      421 gaagtcggct gaagcattgt caataacagg tgtaatatca gcattgtcaa atggatcacc
      481 aactgttaat ttagaaactt cttcctgaag caaagtagct aatttatctg ctacactttc
      541 gagaacaatg acacgtttaa tggccgtgca acgttgtcct gagtagctaa aggctcccgc
      601 aacaatttgc ttggcagcat gttccaaatc tgcatcttct agtacaagag ctgcatcttt
      661 cccaccaagt tccaacatga taggacgcat accagctaaa cgaccaatac gttctccaat
      721 aggagttgaa cctgtaaagt tgatgaagtt gacttctttg tgctcaatga tataatcccc
      781 aatttctgaa ccacgacctg taatggtgtt gaaaacacct gccggaatcc ctgcttcttc
      841 aaatgcttta gccaacaaga gtccagaaat ggaaccttgt gttggtggct taaacatgac
      901 cacattccct gcaatcaagg caggtgcaat tttagaagca gataaattaa ctggataatt
      961 aaagggagca atcgctagca cgataccaac tggttcacga cggacaacag ccagtttgtt
     1021 tttacttgct gcctcaaaac caccaccttc cattgcttgt ccagtgatac ggagaccttc
     1081 ctcagcagca taacgaatca agtctgctgt acgcactact tctccaattg ctgctttaat
     1141 cccttttgct acttctttgg caaggatagt accaatttct tccttatcgc gttctaaaat
     1201 agctgctgtt ttatgtaaat aagccgcacg ttcaactgct gataaagctc gccatgctgg
     1261 cagggctgca cgcgcagctt gcatagcctc atcagcttca gtctgagtca tggctggaac
     1321 tgtacccaat tcttcttgat tgattggtga ataaatcgta atttcttgtt cagatgattt
     1381 ccattttcca tttactaaat tctgatatct tgtcaaattc ttgtcctcct gaaaatgatt
     1441 aagatatatt ttaccaaatt ttcagaaaat cacaaccctt tttgcaaaat ttttgagatt
     1501 attttcacaa acttgatttt tcaaagtata ctcaataaaa ataaaaaaaa tccactacgt
     1561 caaggcgagg ctaatgtggt ttgaagaaat tttcgaagag cgtgaatgag tatcatctat
     1621 agtaaaataa aaaaactgaa caatttggtt ggggacagcc aaaccaattt ctcacaatgt
     1681 ttcagaaaca agggtgtgct actccaattt cagcctacta taactgtcat agattgctga
     1741 aacaaagtct aggtaaaagt cttcataata aaaagacctc ctatcaagtg ttcaaaaact
     1801 ttgataggag gtcttgtttt gtgaaaatat ttatcaaatt ttctatacaa gtgagctgtt
     1861 agccaggttc tttctattct ttcaatttca atgaatggat tttttactaa tactcataac
     1921 tgggaatttg tctgtgtaaa aatagcgaga tagatggtat ttataaaaca ctcaagacag
     1981 ctagactaat atcatttaaa acattatctt cttttgagcg actgttggtt accaacatag
     2041 ctaaatttcc tgcattttca aattgatagg gttctgattt agcattcaca accaccaaga
     2101 ggtgttcttt gccgtgaact tcatagataa ggtagccgct atgttcaatc gcagaatgca
     2161 caaagacatg atggtaaatt tcatcatagc tagagtaaga aaaggcacca gtttttgtct
     2221 tcaatcggat gacttgacgg ataaactcaa tactgtcttg acgctcatta atcaagttcc
     2281 agttcacttg gttcacactg tcaggagcat tatagctatt catcgcacgc tctctatcat
     2341 catgggtcaa ctcaccattt tcaccagtcg caaccagttt ggtacgacca aattcttgac
     2401 cgatttccat aaaggccatc ccctgcatga gcagattcat ggctgtggca gtttcgacct
     2461 tgcgcatgat ttgctctgaa ctttggtctg gatgaagggt tgccaataaa tcgtgaagat
     2521 tgtaattgtc atgggcttct acatagttaa gcacctgatt tggatgtgta tagcttccta
     2581 attcacgact tcctaggatt gctttagcta gaattggctc tgtcgcagca ccactgacaa
     2641 aacctgactt gatagcacca taaacttctc cccctttgac agcatcgcgc tgattgtcat
     2701 taaagaaacc aatatttggc atctggtagg cattgtcctt cttggcctta tcataagggg
     2761 caagacctgt tcccatatcc catccttctc catagaggat aatgttggag tcgatttcat
     2821 ccaagctttg acgaatcatc tgcatggtct tgacatcatg aatccccatc aagtcaaaac
     2881 ggaagccgtc aatattatat tcctgcaccc agtatagaag agaatcaatc atatacttgc
     2941 gaaacatttc gtgttcactg gctgtttcat ttccaacacc cgttccattc tggaaggtac
     3001 catctggatt catacgataa tagtaatcag ggactgttgt ttggaatggt gcatcaacaa
     3061 ctgagaaggt atggttatag actacatcca taatgactcc aatacccgca tcgtgataag
     3121 cttgaaccat caccttcaaa tcacgaatga cctgagctgg atcatctgga ttagttgaaa
     3181 aactagtttc tggcgcgtta tagttttgtg gatcataacc ccagttgtag gttacatttc
     3241 catcctcatc gtattcttta tgacggtctg caattggttg caattgaaca taattgtagc
     3301 ccagcttctt gatgtaatca aaagcagttg actggccgta ttggttaact gttccagcct
     3361 gagcagcacc caagaaagtt cctcgaagat gttcatctac acccgatgta ggtgatttag
     3421 tcaaatcacg aatatgcatt tcacagataa ctgccttaca tggattttcc aagcgccaag
     3481 tagcctccga accgtgctta acctcgaagt tttcaacttg cttttctaca tggctcagaa
     3541 tagctgaacg tttgccatca gggctggtcg cgattgtata aggatcacgt gtcagtgttt
     3601 ggtgatgagg gaattggact tgatactgat aagccttacc taccaaatct tcctcaacat
     3661 ccaaactcca gacaccgatt gtattgtcct tatgattata agagtagcta ttgcctcttt
     3721 tcatctcaaa agtcttccaa acgggtgcat cattagcagc tgattcataa acgacaactt
     3781 gcacttctgt cgctgtaggt gaccagaggg aaaaatgagc ctgattgtcc tctacacggc
     3841 aacccaattc tccttggtaa ccccaatgat ggtcaaaact agcactgtta atggccttat
     3901 caaaggcaaa aggattttga tttttataga aaggactggc aatagcagga ttttcagagt
     3961 aataaatcct atcatcgcct tccaaaatcc agacctctgt taatagggga tagtgattaa
     4021 aacggataga atattcttta ctagtttgac ctgtatgaac cacaaaattc aagctttcta
     4081 taacatgtga acttgggtgt tcaaagctaa ataaagctcc aaaataatct tctttgtagg
     4141 ttagcaaatc aattcgttga tcctgacttt ttacaaagga gcaagtgtca tattctccat
     4201 tcttacgatg gtaatgaatg cgcatagggt agttatacat tttttatttt tcctttttac
     4261 tttgtttcta tttcactaat aaatttttgt caatctcgtc tcaattaaca gacatagtca
     4321 tattctctaa actctgtttt taaacgatcc attacaaact ttctagccat gcctcatctc
     4381 tgacctggat accaagttct tgtgcttttt gcagtttact tccagcgtct gcacctacca
     4441 cgacgaggtc ggtcttttta gaaatactac ctgtcacttt ggcacccaga ctttcgagtt
     4501 tacttttagc ttctgagcgc ttgagtcgtt ccaattttcc tgtcaatacc acggtcaaac
     4561 ctgacaaggc cgcatccgct actaccgtct gtcctttata gtccagattg accccagttt
     4621 ctttcaattc tctgagcaga atttcagagc cttctgtcgc aaaataagtc tgaagacttt
     4681 tggcaatcac gccacctaga ctttcaatac tagccacttc ctctgaatct gcctgagaca
     4741 gattttcaat tgaatggaaa tattgaagta aaagctgact aaccttgctt ccgacatgac
     4801 gaattcccaa accaaataag agcttctcgg cagaattttc ctttgatgct tggatagcct
     4861 gatacagttt agcagcggac ttttccttaa ccccctctaa aaggaggaaa tcctcttctt
     4921 gcaaacgata aatatccgcc acatccttga ctaaattagc agcaaaaagc ttctcaacaa
     4981 tagatggacc aaggcctgta atattcatag catcacgaga agcaaagtga atcaagcctt
     5041 ccatgatttg agcagggcaa cgcggattga tacaacgtag ggccacttca tcttcaaagt
     5101 gcaacaagtc agagttacaa cttggacagt ttgtagggat atctagtttt tcttcagaaa
     5161 cccgtttgga ctctaccaca cgtaaaacgg cagggatgat gtcaccagcc ttatatacaa
     5221 tgaccgtatc gtcttttcgg atatcttttt cagcaatata atctacattg tgcagggtcg
     5281 cacggctaac agtcgtaccg gcaagttgta ctggtgttag attagcagtt ggagttacaa
     5341 caccggtacg gccaactgtc cagtcaactg ataagagttg agcttctttt tcttcggcag
     5401 ggaacttgta ggctactgcc cactttggag ccttaactgt aaaaccaagt tcttcttgac
     5461 ttgctaggtc gttgaccttg attaccactc catcaatatc gtaaggcaga ttttcccgtt
     5521 cctgtcctac ttcttggata aaattccaga tttcatctat gttttcagcc aagattcgct
     5581 taggattgac cacaaaacct agttgttcta ggtacttcaa acccttttct tggctatcac
     5641 gagttgaagg gctggcttct tgatagagaa acgttgcaag attacgcttg gcaactactg
     5701 ctgtatccaa ctgacgcaga gttcctgctg ccgcattacg aggattagca aattcaggct
     5761 ctccattttc ttggcgcact tggttaactt ggtcaaagga agcgcgtggc atgtaacatt
     5821 ccccacgaac tgtgatatct agttcttctg gcaaagtcaa agggatgtcc ttaacacgct
     5881 tgaggttttc tgtgatattt tcaccaattg aaccatctcc acgtgttacc ccagcaacca
     5941 aaatcccctt ttcataagtc agcgagatag ataagccatc gattttcagc tcacaaatat
     6001 aggtcggatg agccacttcc ttacgaacac gcgcatcaaa agcatctagc tcctcacgtg
     6061 aaaaagcatc ctgcaaacta taaagaggat actgatgact gtatttttca aaaccatcta
     6121 aaaccttgcc accaacacga tgagtcggac tgtctgctag cacttgctct ggataagcag
     6181 tttctaactc gaccaactca cggtaaaggc ggtcatactc actgtctgca accgagggat
     6241 tatcgctggt atagtactca gtcgcatagc gattgagcaa agcgactaac tcattcattc
     6301 ttttattcat aagaccattt taccataaaa caagccctcc tcacaaacga gaagggcgga
     6361 aaaaacactt agtttgaaat tatttttgaa actcaagcaa ccttatatca atttttcaaa
     6421 atgagttcga acataaataa acgatataca agacaagatg ataacaccac ttccaattat
     6481 caggaaagaa gagagatgta cacttggcaa gactgtcata aatccttttg caataggcat
     6541 aaatagaata gctaaggtaa aaattgtact cagtactctt ccaagaaatt cgctctcaac
     6601 cttggtttgt acttgagtaa aaaagtgaat attaaaaatc gtcataaaca attcacaaac
     6661 taaatttcca gaaaaggaaa gaaaagttgg aagtggtaat cccatcataa aaactccgac
     6721 acctgtcaaa gccagtaaaa tcaaaagatt ataaatatta gctttaattt tactagctag
     6781 aagagcccca atgatggaac caatagcccc catagttaaa atacttgcat aggctccttc
     6841 tgacccgtaa agctgattcg aaaagggaag tagaaattca aaagctgcaa aaaagaaatt
     6901 aacgctggaa gctaccagca aaaggaagaa aatttcttgc tgatgccaga tatagtgtaa
     6961 cccatccttg atatctacaa aaatatctct cccagtaaaa gcctttttct cttgaacttt
     7021 tgcttcctct tttggaagga aagccactag aacaaaagca atgaaaaaag tcagcgagtc
     7081 tagcagtagc gtcatattga gacttgcaaa ctgtaaaaca aggaaggaaa gaacaggaga
     7141 gctaacacct acaacctgca aaaccagctc taagcgagaa ttatagatca caatctcatc
     7201 tttctccacc acttcagtta tgatagcttt attggctgtg cgagaaaagg caaaagcaat
     7261 agcctgcaca atgttagcaa caatcaaagc gccaatcatc cagctatcat tccttatgaa
     7321 agaaatagcc agacaaagaa tcccacaaac aagatctgcc gtcattaaaa tcttacgacg
     7381 agaaaaacgg tctgaaataa ctccgccaaa gggattgacg agaatagatg tgacgagctc
     7441 agaaatctga tacattccta aaactgtctg tcctatagtc cccatagaag ccaaccagac
     7501 actatttcca taatcataga gcatatttcc cattttattg atagccccac ggctaatcaa
     7561 ctgcactgca tagcgattca tattaaagct cctctcaaat tttgaaacta ttgtatcaaa
     7621 accgaaagga gctttttatt ttttccctta tttgggaaaa ttaacttttg acaaattttt
     7681 cgtagtgttc ctgataatag gctacttgct ctggaagacc taacacatca aaaatatgca
     7741 tggccttttg catctgctta cagccttctt tacactgtcc tttttgatat aaggcaaaac
     7801 cttttaaata atggaaaaca ttacgctcat aaagcttaat acctttgtca ataatcttct
     7861 ctgtataagc ctcaaaatag ttggcattat aaaaagaaga atgctctaaa caatgctggt
     7921 aacaattgag ggccaaaatc aaaactaatc tcttatggcg actaatctct tggtaaaatt
     7981 cctccctctc cataacttct ctaccaatcc gagtgacata gtctacatcg tagaaactat
     8041 agaggttacc gaaaagaatc aactcataca tggtccattc ttctgttttg aagagataat
     8101 ctgctacctt atccaaatca tcctgcttca tatcataagt cgcatctctt tgacaaatca
     8161 gaccttgtag caaaatccag ttcagctcaa aataaaggga agtcgtcgaa ctcttagact
     8221 tttcaagttg ttctctttga agcttttgaa aacctgcaat atcgtttgaa tagtaaagtg
     8281 ggataatctg tgccatcata gacacatgtt catgattatg aaaattcctt gccttatcca
     8341 tgaaattttc gattgttaca tgaatgttat ccaaaatctc aaagaaacgg gagactgcca
     8401 ggtcagactc cccaagctca aagcgagata actgagaggt agagcaggat tcgcctgctg
     8461 cttcctttaa agaataattt ccacttgttc gaaattcacg aaatactttt ccaagatgtt
     8521 ccatctttac acctgatctg ataattcttc ccactcaagc atagcttctt cctgacgatg
     8581 gctgattttg tccagctcag cctgtaattc catgagtttg tcggcatcgt ttgtttccaa
     8641 catttgttca gaaatggctt ggctttgact ttctagctct tcaatttcag cttctagact
     8701 ttcgatttgt cgcatgagtt tgcgaacttc tttttgactt tctttctggg cctgatagtc
     8761 attgactgga cttgcttcct ttacttgatt gctagttgaa gcttcctcag tctgactcat
     8821 ttctgctgtt gctttcttct caacatagta gtcgtaatct ccaaggtaga gagttgaacc
     8881 attctcagac aattccaaaa catgagttgc cacacgattg ataaagtaac gatcatgact
     8941 gacaaaaagc aaggtaccat caaagtcaat caaggcattt tctagcactt ccttactatc
     9001 aatatccaag tggttggtcg gctcatccag aatcaaaaag ttattgtttt ccatagacaa
     9061 tttagctaaa agcaaacgag ctttttcgcc accagatagc atgccgactg attttttaac
     9121 atcatctcct gagaaaagga aggccccaag acggttgcgg atttcaactt ctggtgtcag
     9181 tttgaaatca ttccagagtt catccagcac cgtattactt ggtgtcagct tgctttgggt
     9241 ttggtcatag taaccaacct caacattagc gccaaagcgc ttttcacctt tgataaaagg
     9301 aatctggtcc acaatagact tgataaaggt tgacttgccg ataccatttg gaccaacgat
     9361 agcgacagca ttcatcttac gaagatctag gttgataggt tgtgacaaaa cttccccgtc
     9421 ataaccaata gcagtatttt caacagtcaa aacaacattg cccgacgttt tttcagactg
     9481 gaaggtcatg ttggctgctt tcttgccagc ttcaggcttg tccaaacgct ccattttttc
     9541 tagttgttta cggcgagatt gagcacgttt ggtcgttgaa gcacgaacta gattgcgatt
     9601 gacaaagtct tccagagcag cgatttcctt ctgttgcttt tcatagtttt ttgcctcagt
     9661 agctagcttt tgctccttca actcaacaaa acgagagtaa ttccccacat agcgatccaa
     9721 ggaatacttg gtcaaatcta gcgtaattgt cgcaaccttg tccaagaaat aacggtcgtg
     9781 gctgacgata atgagggcac cgctatagtt taccaagtaa ttctctagcc aggagatggt
     9841 ttcaatatcc aagtggttag ttggctcgtc caagaccaag agattgggct tttcaaggag
     9901 cattttagct agagccaaac gagtattttg accaccagaa agctcagcaa ttttcatctg
     9961 ccacatagac tcgtcaaact tgaatccatt caaaatcgct cgaatatcag cttcataggt
    10021 aaagccacct gcttggcgaa aattttcaga taagcggtca taatctgaca tcagtttatc
    10081 caaatcctca ccagactttt cacccatctc cagctccatc tgacgcagtt gtttatctgt
    10141 ccgacgtaag tcatcaaaga catgaagcat ctcatcatag atggtatttt cagactcaaa
    10201 acggctatct tgagctaggt aagacagaga aatatctttt ttcttattga tttctccact
    10261 agttggctcc tcttctccaa ctaaaatctt caaaagagta gacttacctg caccattttt
    10321 cccaacaagg gcaatccgat ctcgttcatc aacctgcagg ttgatattat cgaaaagaac
    10381 ctctcctgca aaagaacgtt caattttatt agcttgtaaa ataatcatac aagtagtata
    10441 gcatgtttcc ctaaggcatt caagataatc gtaagtcttt tagtacaact tttataacat
    10501 aaaataaact aaattatgta tattttatat tagattcctt cactatcttg ttggattttc
    10561 taaccagcta atcttgtttc aaatagttat cgcacaagcc tattatttaa ttcttttcat
    10621 tatttacgta cgc
//
LOCUS       DAVHTH010000060        10570 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.060, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000060 DAVHTH010000000
VERSION     DAVHTH010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10570)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10570)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10570
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.060"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            complement(79..1032)
                     /locus_tag="VVR63_001738"
     CDS             complement(79..1032)
                     /locus_tag="VVR63_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEU6129731.1"
                     /translation="MSISQRTTKLILATCLACLFAYFLNLSSAVSAGIIALLSLSDTR
                     RSTLKLARNRLFSMLLALAIGVLAFHLSGFHIWSLGLYLAFYVPLAYKMGWEIGITPS
                     TVLVSHLLVQESTSPDLLVNEFLLFAIGTGFALLVNLYMPSREKKIQHYHTLVEEKLK
                     DILQRFKYYLSRGDGRNRAQLVAELDTLLKEALRLVYLDHSDHLFHQTDYHIHYFEMR
                     QRQSRILRNMAQQINTCHLAASESLILAQLFSKIAGQLSQTNPASDLLDEIERYLEVF
                     RNRSLPKTREEFETRATLLQLLREAKTFIQVKVDFYQKYRQ"
     gene            complement(1100..2309)
                     /gene="sstT"
                     /locus_tag="VVR63_001739"
                     /pseudo
     CDS             complement(1100..2309)
                     /gene="sstT"
                     /locus_tag="VVR63_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713440.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
     gene            2448..3008
                     /locus_tag="VVR63_001740"
     CDS             2448..3008
                     /locus_tag="VVR63_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HEU6129732.1"
                     /translation="MQKFIQAYIEKLDVTTIIENILTKVISLLLLLIVFYIAKKMLHT
                     MVQRIVKPSLKMSRHDVGRQKTISRLLENVFNYTLYFFLLYCILSILGLPVSSLLAGA
                     GIAGVAIGMGAQGFLSDVINGFFILFERQLDVGDEVVLTNGPITVSGKVVSVGIRTTQ
                     LRSEEQALHFVPNRNITVVSNFSRTD"
     gene            3065..3973
                     /locus_tag="VVR63_001741"
     CDS             3065..3973
                     /locus_tag="VVR63_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEU6129733.1"
                     /translation="MVLEKQLGHGCTWIDLDLGKLNKLEDLSEIYGLDKETIEYALDR
                     NERAHMDYHRESGTVTFIYNVLDVKKDKAYYETFPMTFIVEHRRLITISNTKNAYVIE
                     QMTRYLENHDTLSIYKFLFASLEIISNAYYPVIEQMDKSRDEVNDLLRQRTTKKNLFA
                     LSDLETGMVYLTAAAKQNRILLEHIQGHALYRSFDEIEREQFDDAMIEAHQLVSMTDL
                     ISQILQQLSASYNNILNNNLNDNLTTLTIISVLLAVLAVVTGFFGMNVPLPLTDEPHA
                     WLYISLASAGLWIVLSLLLRKIAKKS"
     gene            3925..4515
                     /locus_tag="VVR63_001742"
     CDS             3925..4515
                     /locus_tag="VVR63_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HEU6129734.1"
                     /translation="MDCFILVTKENCEKKLRKGARMAIENYIPDFAVEAVYDLTVPSL
                     QAQGIKAVLVDLDNTLIAWNNPDGTPEMKQWLHDLRDAGIGIIVVSNNTKKRVQRAVE
                     KFGIDYVYWALKPFTFGIDRAMKEFHYDKKEVVMVGDQLMTDIRAAHRAGIRSILVKP
                     LVQHDSIKTQINRTRERRVMRKITEKYGPITYKKGI"
     gene            4518..5624
                     /gene="yqeH"
                     /locus_tag="VVR63_001743"
     CDS             4518..5624
                     /gene="yqeH"
                     /locus_tag="VVR63_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HEU6129735.1"
                     /translation="MEEILCIGCGATIQTTDKAGLGFTPQSALEKGLETGEVYCQRCF
                     RLRHYNEITDVQLTDDDFLKLLHEVGDSDALVVNVIDIFDFNGSVIPGLPRFVSGNDV
                     LLVGNKKDILPKSVKSGKISQWLMKRAREEGLRPVDVVLTSAQNKHAIKEVIDKIEHY
                     RKGRDVYVVGVTNVGKSTLINAIIQEITGDQNVITTSRFPGTTLDKIEIPLDDGSYIY
                     DTPGIIHRHQMAHYLTAKNLKYVSPKKEIKPKTYQLNPEQTLFLGGLGRFDFIAGEKQ
                     GFTAFFDNELKLHRSKLEGASAFYDKHLGTLLTPPNSKEKEDFPRLVQHVFTIKDKTD
                     LVISGLGWIRVTGTAKVAVWAPEGVAVVTRKAII"
     gene            5824..6135
                     /gene="yhbY"
                     /locus_tag="VVR63_001744"
     CDS             5824..6135
                     /gene="yhbY"
                     /locus_tag="VVR63_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HEU6129736.1"
                     /translation="MSLTSKQRAFLNSQAHTLKPIIQIGKNGLNDQIKTSVRQALDAR
                     ELIKVTLLQNTDENIHEVAEILEEEIGVDTVQKIGRILILFKQSSKKENRKISKKVKE
                     I"
     gene            6187..6816
                     /locus_tag="VVR63_001745"
     CDS             6187..6816
                     /locus_tag="VVR63_001745"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HEU6129737.1"
                     /translation="MTIELLTPFTKVELEPEIKEKKRKQVGILGGNFNPVHNAHLIVA
                     DQVRQQLGLDQVLLMPEYQPPHVDKKETIPEHHRLKMLELAIEGIDGLVIETIELERK
                     GISYTYDTMKILTEKNPDTDYYFIIGADMVDYLPKWYRIDELVDMVQFVGVQRPRYKV
                     GTSYPVIWVDVPLMDISSSMVRDFLAQGRKPNFLLPQPVLDYIEKEGLY"
     gene            6816..7409
                     /gene="yqeK"
                     /locus_tag="VVR63_001746"
     CDS             6816..7409
                     /gene="yqeK"
                     /locus_tag="VVR63_001746"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HEU6129738.1"
                     /translation="MSYQDYINCSREALLEKMAELLPEKRLTHCLGVERAAMELAQRF
                     GVDVEKASLAGLLHDYAKKLSDQEFLALIDRYQLDPDLKNWGNNVWHGMVGIYKIQED
                     LDLHDSEILRAIEIHTVGAGQMTDLDKVIYVADYIEHNRAFPGVDVAREIASLSLNKA
                     VAYETARTVEYLAHQGFPIYPQTLETYNAFVHYLKED"
     gene            7410..7910
                     /locus_tag="VVR63_001747"
     CDS             7410..7910
                     /locus_tag="VVR63_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEU6129739.1"
                     /translation="MKTAFIIIDVQNVLVETGFQTKSLLEKISYLQNQARSKNIEIIY
                     VQHIENSEAQTSEDWQLSALLNRKPAEKVFQKKYNSIFKETGLKEYLDKQGIEKLVLC
                     GMQTEYCVDTSVKVAFEYGYQLIVPEGAVTTFDGDDIPAETINEFYEDIWEERFADVL
                     DYKHIF"
     gene            7923..8276
                     /gene="rsfS"
                     /locus_tag="VVR63_001748"
     CDS             7923..8276
                     /gene="rsfS"
                     /locus_tag="VVR63_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HEU6129740.1"
                     /translation="MNEKELLELVVKAADEKRAEDILALDVQDLTSVTDYFVITSSMN
                     SRQLDAIAANIREKVAQAGFKGSHVEGDAAGGWVLLDLGAVVVHIFSEEMRAHYNLEK
                     LWHEANSVDISEALA"
     gene            8596..9336
                     /locus_tag="VVR63_001749"
     CDS             8596..9336
                     /locus_tag="VVR63_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001823113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEU6129741.1"
                     /translation="MATYETFAAVYDAVMDDSLYDKWTNFSLRHLPKTKERKKLLELA
                     CGTGIQSVRFSQAGFDVTGLDLSADMLKIAEKRATSAKQKIAFIEGNMLNLSKAGKYD
                     FVTCYSDSICYMQDEVEVGDVFKDVYNALNEEGVFIFDVHSTYQTDEVFPGYSYHENA
                     EDFAMLWDTYEDEAPHSIVHELTFFIKEADGSFSRHDEVHEERTYEILTYDILLEQAG
                     FKSFKLYADFEDKEPTETSTRWFFVAQK"
     gene            9346..10443
                     /locus_tag="VVR63_001750"
     CDS             9346..10443
                     /locus_tag="VVR63_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000156376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HEU6129742.1"
                     /translation="MTITGIIAEFNPFHNGHKYLLDQAEGLKIVAMSGNFMQRGEPAI
                     VDKWTRAQMALENGADLVVELPFLVSVQAADFFGQGAVDILDRLGIDSLVFGTEEVRD
                     YQKIADLYTEKGTEMEKFVENLPDSLSYPQKTQAMWKEFAGLDFSGNTPNHVLALAYA
                     KAVAGRNIKLHPIQRQGAGYHSVNKDVDFASATALRQHQKDQDFLERFMPSVALFEQA
                     SKVIWEDYFPLLRYQILSNPDLTTIYQVNQEMAVRIKEAIKTAQSVEELVELVTTKRY
                     TKARVRRLLSYILAQARENVLPEAIHVLGFTEKGRQHLKSLKGQVSLVSRIGKEPWDA
                     MTQKADQIYQLGNLSIAQQNFGRVPIRIETN"
BASE COUNT         3169 a         2086 c         2453 g         2862 t
ORIGIN      
        1 gttttgaggt tgtggataga actgacgaag tcagtaacat atatacagca aggtgaagct
       61 gacgtagttt gaagagtatt actgtctata tttttggtaa aaatcaactt ttacttggat
      121 gaaggttttg gcttcacgta ggagttgaag aagggtggcg cgggtttcaa actcttctct
      181 tgttttgggc agactgcggt tccggaagac ttccagataa cgttcaattt catctagcaa
      241 atcagaagca ggattggtct ggctcagttg acctgcaatt tttgaaaaga gttgcgctaa
      301 gatcaggctt tcactggcgg caaggtgaca agtgttaatc tgttgggcca tgtttctcag
      361 gatacgactt tgtcgttgtc tcatctcaaa gtagtggata tggtagtcgg tctggtgaaa
      421 gaggtggtca gagtgatcca aatagaccag tctgagggct tctttcaaaa gcgtgtctaa
      481 ttctgctacc agctgtgctc ggttgcgtcc gtctcctctg gataaatagt atttgaagcg
      541 ctggaggata tcttttaact tttcttccac cagcgtgtgg tagtgctgga ttttcttttc
      601 tcgtgaaggc atgtagagat tgaccagtaa agcaaatcct gtaccgatag caaagagaag
      661 gaattcgttg actaggaggt ctggagaggt tgactcttga accaagagat ggctaaccaa
      721 aaccgtgctt ggtgtgatgc caatttccca gcccatcttg taggctaaag gaacgtagaa
      781 ggccagatag aggccgagac tccagatatg aaatccgctc aagtgaaaag ctagaacacc
      841 gatagccaga gctagaagca tagaaaaaag acgattgcga gccagtttta aagtacttct
      901 acgcgtatca gataggctca agagagcgat aattccagcc gaaactgctg acgaaagatt
      961 gagaaaataa gcaaacaggc aggcaagaca ggtagctaag atgagcttgg tcgtacgttg
     1021 gctaatagac ataagaattt cctaataagt tagaataaaa gcgtaaaaga caagacatga
     1081 gcaggcttgc cttgatgagt tattttttac gggttgctgc gtattcggca acggcggtaa
     1141 agaggacatc tgtagaagag ttaagggctg tttcacatga gtcttggatg acaccaatca
     1201 caaaaccaac cccaacaatt tgtatggcaa tatcgttaga aataccgaaa aggctacaag
     1261 caactgggat aagaaggagg gaacctccgg caatacctga agcaccacag gctgagatag
     1321 ctgctaccac actgaggaca aaggctgtgg caaagtcaac aggaattcca agagtgttaa
     1381 ctgtaacaag ggtcaaaagg ttaatggtaa tcgctactcc agccatattg atagtagaac
     1441 cgagtgggat agaaacagaa taggtatctg ggttgagtcc aaggtcatgg cagagtttca
     1501 tattgacagg aatgttagcc gcagaactac gagtgaaaaa ggctgtcaca ccgctgacac
     1561 ggaggcagtt ccaaactaga gggtaaggat tgcgtctcat aaagaagaag gcaatcaaag
     1621 ggttgaccac aggggcaaca aaaagcatag tcgttactaa tagaaccaat aaaataccgt
     1681 agttggcaag gcttccgact cccttgtcag aaatggtttt aaaaacaaga ccaaggattc
     1741 caaatggagt cagattgatg atccattcga caattttaga agtcacgtca gcgatagttt
     1801 ttagcaattc tttactattt ttactggctt ctctcatagc gattccaaaa atgactgccc
     1861 aagataagat tccaatatag ttagcagtaa gcagggcgtt gactgggctg tcaaccagtt
     1921 tgagcaagag gttgctgagg acctgcccaa tcccatctgg tggtgcaatt tcagtattgg
     1981 cactatttag ggtaatttca atagggacga tgaaacttgc tagtacagct acaagagcag
     2041 cggcgaaagt ccctatcata ggatatacaa gaaaacaaca gttttcatat tgctatcttg
     2101 tcccttttga tgttgggaaa gggcattggc aacgagagca aagactagga taggagcaac
     2161 agcttttaga cctccaacga ataaatcccc gagtagccca atccctgaga gattaggaag
     2221 ggtcagtcct aggattcccc acaaagcata ccaatcaaga tacgcttgac aaggcttgcc
     2281 ttattccaag catgaatgat tcttttcata ataatctcct ttttgtgtag tgattatgat
     2341 tatagtataa atgatagaca aaatcaagaa ttttctgtct attttttgaa tatttatgga
     2401 gaatgagact gatgaaaata tggtataatg aaataaagga gttttatatg caaaaattta
     2461 ttcaggctta tattgaaaag ctagatgtga caaccattat cgagaatatt ctaaccaagg
     2521 tcatttctct tttactgctt ttgattgtat tttatattgc taaaaaaatg cttcatacca
     2581 tggtgcagag aattgtcaaa ccttctctaa aaatgtctcg tcatgatgtc ggacgccaaa
     2641 aaaccatctc acgtttacta gaaaatgtgt ttaattatac gctatatttc tttttactct
     2701 actgcatttt gtcgatttta ggtttgccag tttctagttt gctggctgga gctggtattg
     2761 ctggggtagc gattggtatg ggagcccaag gctttctgtc tgatgtcatc aatggctttt
     2821 tcatcctctt tgaacgtcaa ctggatgtgg gagatgaggt cgttctgaca aatggaccga
     2881 ttactgtatc gggtaaggtt gtcagtgtgg gaattcgtac gacacagctt cgtagcgagg
     2941 agcaagccct tcactttgtc cctaaccgaa atatcacagt tgttagcaat ttctcacgca
     3001 cagactagac ctgttatttt aagtaatttg tggtacaata gagggagttt aataaggaga
     3061 aaagatggtt ttagaaaagc agttgggcca tggttgtacc tggatagacc tagacctagg
     3121 aaagttgaat aaactagaag acctttctga aatttacggt ttggacaagg aaaccattga
     3181 atacgcactg gatagaaacg agcgcgccca catggactac caccgtgaaa gtgggacggt
     3241 tacctttatc tataatgtcc tagacgtaaa aaaggacaag gcctactatg agacttttcc
     3301 catgaccttt atcgtcgagc atcgtcgcct gattaccatt agtaatacca agaacgccta
     3361 tgtcattgaa cagatgactc gttatctgga gaaccatgac acgctttcga tttataagtt
     3421 tctctttgcc agtctggaaa tcatcagcaa tgcctactat cctgtcattg agcagatgga
     3481 caagagtagg gatgaggtca atgacctctt gcgccagcga actaccaaga aaaacctctt
     3541 tgccctgtct gatttggaga ctggtatggt ttatctgacg gcagctgcca aacaaaatcg
     3601 gattttgtta gagcatattc aaggtcatgc cttgtatcgt agttttgatg agattgagag
     3661 agaacagttt gatgatgcca tgattgaggc tcatcagctg gtatccatga cagacctaat
     3721 ctctcagatt ttacagcagc tttcagcctc ttacaacaat attctaaaca ataatctgaa
     3781 tgacaatttg acaaccttga ctatcatttc agtcttgcta gctgttttgg cagtcgtgac
     3841 aggctttttc ggaatgaatg ttcccttacc tttaacagat gagccccatg cttggctcta
     3901 tatcagtttg gctagtgcag gtttgtggat tgttttatcc ttgttactaa ggaaaattgc
     3961 gaaaaaaagt taagaaaagg agccagaatg gcgattgaaa attatatacc agattttgct
     4021 gtggaagcag tctatgatct gacagtccca agcctgcagg cgcagggaat caaggctgtt
     4081 ttggtcgatt tggataatac cctcattgct tggaacaacc ctgatggaac gccagagatg
     4141 aagcaatggc tacatgacct tcgggacgcg ggtattggca ttatcgtagt gtcaaataac
     4201 accaaaaaac gcgttcaacg agcagttgag aaatttggga ttgattacgt ttactgggcc
     4261 ttgaagccct tcacatttgg tattgaccgt gccatgaagg aattccacta tgacaaaaag
     4321 gaagtggtca tggttggcga ccagctcatg acagatatac gagcagccca ccgtgcaggg
     4381 attcggtcaa ttttagtcaa acccttggtc caacatgact caatcaaaac gcagattaac
     4441 cgaactcgtg agcgtcgtgt tatgagaaaa atcactgaaa agtacggacc gattacatat
     4501 aaaaaaggaa tttaactatg gaagaaattc tctgtattgg ttgtggagca accattcaga
     4561 cgacagataa agctggtctt ggttttaccc cccagtcggc acttgaaaaa ggtttggaga
     4621 ctggcgaagt ctattgccaa cgctgtttcc gtctccgcca ctacaatgaa atcacagatg
     4681 tccagttgac ggacgatgat ttcctcaagc tcttgcacga ggtgggagac agtgatgcct
     4741 tagtggtcaa tgtcattgat atctttgatt ttaatggatc tgtcatccca ggtttaccac
     4801 gtttcgtctc gggcaatgat gtcctcttgg taggaaataa aaaagatatc cttcctaagt
     4861 cagttaagtc tggtaagatt agccagtggc tcatgaaacg tgcccgtgaa gaaggtcttc
     4921 gtccagtcga tgtggtccta acttcagcac aaaataaaca tgccattaag gaagtcattg
     4981 ataagattga acactaccgt aagggccgcg atgtctatgt ggtcggtgtg accaacgttg
     5041 gaaaatcaac tctaatcaat gctattatcc aagaaatcac gggtgatcag aatgtcatca
     5101 ctacttcacg cttcccaggg acaaccttgg acaaaataga gattccgctt gacgacggat
     5161 cttatattta cgatacaccg ggaattatcc accgccacca gatggctcac tacttgacgg
     5221 ccaaaaacct caagtatgtc agtcctaaaa aggaaatcaa gcctaagacc tatcagctta
     5281 atcctgagca aaccctattt ttaggtggtt tgggacgctt tgactttata gcaggagaaa
     5341 agcaaggatt tactgctttc tttgataatg aactcaaact ccatcgtagc aagcttgaag
     5401 gagctagtgc tttctacgat aagcacctgg gaactcttct gacaccacca aatagcaagg
     5461 aaaaagaaga tttcccaagg ctagtccagc atgtctttac cattaaagat aagacagacc
     5521 tagtcatctc aggcctaggc tggattcgtg taacaggcac agcaaaagtc gccgtttggg
     5581 caccagaagg cgtcgccgtc gtcacacgaa aagcaattat ttaaaacaaa atcgctgagc
     5641 gaacaaagtg agctcatata gcgatagtta ttgccaatct gtagattggc aaggggcaca
     5701 attgagacca aggctcaatt gtgaggtcag gaaatccatt tttcaaagat gaaatctttg
     5761 gaaaattagt tccgaccgtc cctcaccacc taaaataact atccaaaaac aaggaagaaa
     5821 attatgtcat taacatcaaa acaacgtgcc ttcctcaaca gccaggcaca caccctcaaa
     5881 cctatcatcc aaatcgggaa aaatggactc aacgaccaaa tcaaaaccag cgtccgtcaa
     5941 gctcttgatg cgcgtgaatt aatcaaggtt actctcttac aaaacacaga tgaaaacatc
     6001 cacgaagtag ctgaaatttt ggaagaagaa atcggtgtgg atacagtcca aaaaatagga
     6061 cgtatcttga ttttgtttaa acaatctagc aagaaagaaa atcgcaagat ttctaagaaa
     6121 gtcaaagaaa tctaagaccg aaactccaaa taactgtttt tatagagaaa taaaggggac
     6181 tagcctatga caatcgaact attgactccc tttaccaagg tagagttgga gccagaaatc
     6241 aaggagaaaa aacgcaaaca agttgggatt ttagggggga attttaaccc tgttcacaat
     6301 gcccatctca ttgttgcgga tcaagtacgg caacagttgg gactggatca agttcttctc
     6361 atgcctgaat accaacctcc tcacgttgat aaaaaggaaa ccatccctga acaccatcgt
     6421 ctcaagatgc ttgagttggc aattgaggga attgacggcc tagtcattga aaccattgag
     6481 ttggagcgca agggtatttc ctacacctac gacaccatga agattttgac agagaagaat
     6541 ccagatacgg attattactt tatcatcggt gccgacatgg ttgactatct gcctaagtgg
     6601 taccgaattg atgaactggt tgacatggtt cagtttgtgg gggttcagcg tccacgctac
     6661 aaggtaggga cttcctatcc agttatctgg gtggacgtac cgctcatgga tatctcgtcc
     6721 agcatggtgc gggacttcct tgcccaaggt cggaaaccca actttctcct acctcagcca
     6781 gtgctagact acatcgagaa ggaggggctc tactgatgtc ctatcaagac tatatcaact
     6841 gctcccgtga ggccttgttg gaaaaaatgg cagagcttct acctgagaaa cgtctaaccc
     6901 attgtctagg tgtggagcgt gccgctatgg aattagctca gcgctttggt gtagatgttg
     6961 agaaagcaag tctagcaggt cttcttcatg actatgctaa aaagttgtca gatcaggaat
     7021 ttctagcctt gattgaccgt taccagctag accctgacct caaaaactgg ggcaataatg
     7081 tctggcatgg tatggtcgga atttacaaaa ttcaggaaga tttggatttg catgattctg
     7141 aaattctgcg agccattgaa attcatacag tcggagctgg tcaaatgaca gacctagata
     7201 aggtcatcta cgtcgcagac tatatcgagc acaatcgagc ctttcctgga gtagatgtgg
     7261 cgcgtgagat tgcaagtcta tcgctcaata aggcggtggc ctacgaaaca gctcgtaccg
     7321 tggagtatct agctcatcag ggattcccca tctatcccca aacccttgaa acctataacg
     7381 cctttgtgca ctatttgaaa gaggactaaa tgaagacggc ttttataatc attgatgttc
     7441 agaatgtttt agtagaaact gggttccaga caaaaagtct attggaaaaa atttcttatt
     7501 tacaaaacca ggctagaagc aagaatattg aaattatcta tgttcaacat attgagaact
     7561 ctgaagctca aacatcagaa gattggcagt tatctgcgct tttaaatcga aaacctgctg
     7621 aaaaggtctt tcagaagaag tataacagta ttttcaaaga aactggctta aaagaatact
     7681 tggataagca ggggattgaa aaattagttt tatgtggtat gcagacagaa tattgtgtgg
     7741 atacctctgt caaggttgcc tttgaatatg gctatcagct tattgttcca gaaggtgctg
     7801 tcacaacctt tgatggggat gacattccag cagaaacgat taatgaattt tatgaggaca
     7861 tttgggagga gcgctttgca gatgttctag attacaaaca tattttctaa aaagaggatt
     7921 aaatgaacga aaaagaatta ctagaactag tcgtgaaagc ggctgatgag aaacgtgcgg
     7981 aggatatcct cgcacttgat gtacaagatt tgactagtgt gacggactac tttgtcatca
     8041 ctagctcaat gaatagccgt cagttggacg ctatcgcagc taatatccgt gaaaaagtag
     8101 ctcaagcagg ctttaaaggt agccatgtcg aaggcgatgc agctggaggc tgggtcttac
     8161 tggacctcgg tgctgttgtc gtgcatatct tttcagaaga aatgcgtgcc cattataatc
     8221 tagagaagct atggcatgag gcgaattcag tagatatttc agaagctctt gcttagaaga
     8281 tgaactcagt tgtagtcaac tgggtttctt tgcttatttt agaaaaattg atagaaaggt
     8341 aaaggacctc gtgtttgttt catttcgaaa ctgaacacga gctaaaagct gagataaaaa
     8401 gtaactttct ttgtatctga cgatagggaa gaaagtttcc tatgtactct ttgcttttaa
     8461 ggctctttgt atcttagaaa ggatttgaac ccgtcctgta attctcggaa aatagatagc
     8521 cttccttgga gctcggctcc atcgtaaggc tcctaatttt ctatcgaatt acgggcggac
     8581 ttggtatcat gttttatggc gacttatgaa acctttgcgg cggtctatga tgcggtcatg
     8641 gacgatagtt tatacgacaa atggacgaat ttttctctgc gtcatttgcc taagaccaag
     8701 gagagaaaga aactcttgga attggcttgt gggacaggaa ttcaatcagt gcgcttctct
     8761 caggctggtt ttgatgtgac tggacttgac ttgagtgcgg atatgttgaa gattgcggag
     8821 aagagagcaa cttcagccaa gcaaaagatt gcttttatag aaggtaatat gctgaatttg
     8881 tccaaggcag ggaaatacga ttttgtcacg tgttattcgg actctatctg ctatatgcag
     8941 gatgaggtgg aagtagggga cgtctttaag gacgtgtaca atgcgctgaa tgaagaggga
     9001 gttttcatct ttgacgtgca ctcgacctac cagacagatg aagtattccc tggctattcc
     9061 taccatgaaa atgcggaaga ttttgccatg ctttgggata catatgagga cgaagctcct
     9121 cactccatcg tgcatgagct gactttcttt atcaaggagg ctgacggttc ctttagtcgc
     9181 cacgatgaag tacatgagga gaggacctat gagatcttga cctatgatat cttgctggaa
     9241 caggctggat ttaagtcctt caaactctat gcagactttg aggataagga gccaacagaa
     9301 actagcaccc gttggttttt tgtggcgcag aagtaggaga acatcatgac catcacaggt
     9361 attatcgcag agttcaatcc ttttcataat ggccataaat acctgctgga tcaggcagag
     9421 ggactgaaaa ttgttgccat gtcagggaat ttcatgcagc gtggagagcc tgctattgtg
     9481 gataagtgga caagggccca gatggcgctg gaaaatggcg cagacttggt agtggaattg
     9541 ccctttttag tcagtgttca ggcagctgat ttctttggtc aaggagctgt ggatatcttg
     9601 gatcgcttgg gcattgatag tctagttttt gggacagagg aagttcgaga ttatcagaaa
     9661 atcgctgact tatacacaga gaaaggtact gagatggaga aatttgtgga aaatctgcct
     9721 gattcccttt cctatcccca gaaaacccaa gctatgtgga aggaatttgc tggtcttgat
     9781 ttttcaggta atacccccaa tcatgttctt gctctggcct atgccaaggc ggttgcagga
     9841 cggaatatca agctgcatcc gattcagcgt cagggggcag gttaccattc tgtgaataaa
     9901 gatgtggact ttgcctcggc gacagccctc cgtcaacatc agaaggacca agatttctta
     9961 gaacgtttta tgccttctgt tgccctattt gagcaggcca gtaaggtgat ctgggaagac
    10021 tattttccct tgctccgcta tcaaatcttg tcaaatcccg acctaaccac catctatcag
    10081 gtcaatcaag aaatggctgt gcgcattaaa gaagctatta aaacagccca gtctgtggaa
    10141 gaattggtcg agttagtgac taccaaacgt tacaccaagg cgcgtgtcag acgcctcttg
    10201 tcctatatct tggcgcaggc tagagaaaat gtcttgccag aagccattca tgtccttgga
    10261 tttactgaaa aaggcaggca acatctcaag tctttgaaag gtcaggtcag tctagtcagc
    10321 cgaattggca aagaaccttg ggatgctatg acccaaaaag cagaccagat ttaccaacta
    10381 ggaaatctaa gtatagcaca acagaatttt ggaagagtgc cgattagaat agaaacaaac
    10441 taagtctacc gaaaggtgga ctttttgaga ttttttacga ataatactct tcgaaaatca
    10501 aattcaaatc gcgtcaacgt cgccttgccg tactcaagta cagcctgcgg ctagtttcct
    10561 agtttgctct
//
LOCUS       DAVHTH010000061        10428 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.061, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000061 DAVHTH010000000
VERSION     DAVHTH010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10428)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10428)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10428
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.061"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            complement(104..176)
                     /locus_tag="VVR63_001751"
     tRNA            complement(104..176)
                     /locus_tag="VVR63_001751"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(141..143),aa:Thr,seq:ggt)
     gene            complement(276..785)
                     /locus_tag="VVR63_001752"
     CDS             complement(276..785)
                     /locus_tag="VVR63_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HEU6129743.1"
                     /translation="MKKLTIRDVADIAIVAAIYVVLTVTPPLNAISYGAYQFRISEMM
                     NFMAFYNPKYIIGVTIGCMIANFFSFGLLDVFVGGGSTLVFLSLGVWLFAKYSKDYLF
                     NGLIRKDHFFFSILFSISMFTIAAELNIVAELPFFLTWFTTGIGEFASLIIGAIIIGK
                     IGRRIDLSK"
     regulatory      complement(783..879)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            908..1339
                     /locus_tag="VVR63_001753"
     CDS             908..1339
                     /locus_tag="VVR63_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HEU6129744.1"
                     /translation="MKKPIQKFFNNEILAYLFFGLATTLVSILSRLVIYQLSHQELLA
                     TALANIIGILFAFITNDTIVFKQKKKNRLIRLVKFSLARLSTFLLDLFLTFLFVTQFP
                     HIIGQFVTENIDKINAIETIIAQIFIIIINYILSKVYIFRK"
     gene            1421..1798
                     /gene="mscL"
                     /locus_tag="VVR63_001754"
     CDS             1421..1798
                     /gene="mscL"
                     /locus_tag="VVR63_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HEU6129745.1"
                     /translation="MLKNLKSFLLRGNVIDLAVGVVIASAFGAIVTSLVNDIITPLIL
                     NPALKAAKVERIAQLSWHGVGYGNFLSAIINFIFVGTALFFIIKGIEKAQKLTGIKKE
                     KTAEKKPTELEVLQEIKALLEKK"
     gene            complement(1840..2934)
                     /gene="hemH"
                     /locus_tag="VVR63_001755"
     CDS             complement(1840..2934)
                     /gene="hemH"
                     /locus_tag="VVR63_001755"
                     /EC_number="4.98.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="HEU6129746.1"
                     /translation="MKKAILMMTFGSPEEITFEGVADFFTNIRRGVRPQDHEIQTLYD
                     NYVRIGGTPLQKITRQEVALVEARLGNEYSVYFANKFSSPFIPDVIGQMEADGIEQCI
                     CLILEPHYSFYSVMGYEKFLESKQIQFLVIKDWYQEEALLNYWADEIAKILKEEVKQD
                     SFKVIFSAHSVPIFALDFGDPYIDQIFENSKLVAEKLGLSSEQYTNTWQSESDIGIPW
                     IKPDVLEYLREQTEHPDHYIFVPISFISEHIEVLFDNDVECYDLCQEFGVNYHRPPMP
                     NTDSRLIDALVNTVRVNENQEFKEFLPEEETFDELVPSDETKNILAESEDLQMPEFVK
                     KLIEKKGRENVKMPYLIKKMLEKAGKLPKE"
     gene            3089..4312
                     /gene="pepT"
                     /locus_tag="VVR63_001756"
     CDS             3089..4312
                     /gene="pepT"
                     /locus_tag="VVR63_001756"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000222045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HEU6129747.1"
                     /translation="MTYPNLLDRFLTYVKVNTRSDEHSTTTPSTQSQVDFATNVLIPE
                     MKRVGLQNVYYLPNGFAIGTLPANDPSLTRKIGFISHMDTADFNAEGVNPQVIENYDG
                     GVIELGNSGFKLDPADFKSLEKYPGQTLITTDGTSLLGADDKSGIAEIMTAIEYLTAH
                     PEIKHCEIRVGFGPDEEIGVGANKFDAEDFDVDFAYTVDGGPLGELQYETFSAAGAEL
                     HFQGRNVHPGTAKEQMVNALQLAIDFHNQLPENDRPELTEGYQGFYHLMDVTGSVEEV
                     RASYIIRDFEKDAFEARKASMQSIADKMNAELGSYRVTLNLTDQYYNMKEVIEKDMTP
                     ITIAKAVMEDLGITPIIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEYVSLQTM
                     ERAVDTIIGIVAYKG"
     gene            complement(4348..4977)
                     /locus_tag="VVR63_001757"
     CDS             complement(4348..4977)
                     /locus_tag="VVR63_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6129748.1"
                     /translation="MSKVNQLLEQIHEEGIRQSLAEEVENLKAATNKADADLDEVNSQ
                     VKDVLTRIASALQQEKENAEQDSQTLVLYQKLYDILMSLHSYLESNNGSDADFDKVDA
                     LLDQLSAKSKDKTALLESTKAILVLNHQIQSKASASEETSPARNAEANSDNTSAENQP
                     NATAESNIEIASDENKPSNTRDSKPAESTSENETTESSTTTGNQEKPVE"
     gene            4942..5163
                     /locus_tag="VVR63_001758"
     CDS             4942..5163
                     /locus_tag="VVR63_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6129749.1"
                     /translation="MDLFQELIYLAQKTFYFFLAICRRLLVAIYHVLLKQESYNPRLQ
                     GLTEIRNPDKTMFVQDAIRFAQQHGFNML"
     gene            complement(5434..6445)
                     /locus_tag="VVR63_001759"
                     /pseudo
     CDS             complement(5434..6445)
                     /locus_tag="VVR63_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669441.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            complement(6671..9790)
                     /gene="phtE"
                     /locus_tag="VVR63_001760"
     CDS             complement(6671..9790)
                     /gene="phtE"
                     /locus_tag="VVR63_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtE"
                     /protein_id="HEU6129750.1"
                     /translation="MKFSKKYIAAGSAVIVSLSLCAYALNQHRSQENKDNNRVSYVDG
                     SQSSQKSENLTPDQVSQKEGIQAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDALFSE
                     ELLMKDPNYQLKDADIVNEVKGGYIIKVDGKYYVYLKDAAHADNVRTKDEINRQKQEH
                     VKDNEKVNSNVAVARSQGRYTTNDGYVFNPADIIEDTGNAYIVPHGGHYHYIPKSDLS
                     ASELAAAKAHLAGKNMQPSQLSYSSTASDNNTQSVAKGSTSKPANKSENLQSLLKELY
                     DSPSAQRYSESDGLVFDPAKIISRTPNGVAIPHGDHYHFIPYSKLSALEEKIARMVPI
                     SGTGSTVSTNAKPNEVVSSLGSLSSNPSSLTTSKELSSASDGYIFNPKDIVEETATAY
                     IVRHGDHFHYIPKSNQIGQPTLPNNSLATPSPSLPINPGTSHEKHEEDGYGFDANRII
                     AEDESGFVMSHGDHNHYFFKKDLTEEQIKAAQKHLEEVKTSHNGLDSLSSHEQDYPSN
                     AKEMKDLDKKIEEKIAGIMKQYGVKRESIVVNKEKNAIIYPHGDHHHADPIDEHKPVG
                     IGHSHSNYELFKPEEGVAKKEGNKVYTGEELTNVVNLLKNSTFNNQNFTLANGQKRVS
                     FSFPPELEKKLGINMLVKLITPDGKVLEKVSGKVFGEGVGNIANFELDQPYLPGQTFK
                     YTIASKDYPEVSYDGTFTVPTSLAYKMASQTIFYPFHAGDTYLRVNPQFAVPKGTDAL
                     VRVFDEFHGNAYLENNYKVGEIKLPIPKLNQGTTRTAGNKIPVTFMANAYLDNQSTYI
                     VEVPILEKENQTDKPSILPQFKRNKAQENSKLDEKVEEPKTSEKVEKEKLSETGNSTS
                     NSTLEEVPTVDPVQEKVAKFAESYGMKLENVLFNMDGTIELYLPSGEVIKKNMADFTG
                     EAPQGNGENKPSENGKVSTGTVENQPTENKPADSLPEAPNEKPVKPENSTDNGMLNPE
                     GNVGSDPMLDPALEEAPAVDPVQEKLEKFTASYGLGLDSVIFNMDGTIELRLPSGEVI
                     KKNLSDLIA"
     gene            complement(10000..>10428)
                     /locus_tag="VVR63_001761"
     CDS             complement(10000..>10428)
                     /locus_tag="VVR63_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HEU6129751.1"
                     /translation="DHVRKNKADQDSKPDEDKGHDEVSEPTHPESDEKENHAGLNPSA
                     DNLYKPSTDTEETEEEAEDTTDEAEIPQVEHSVINAKIADAEALLEKVTDPSIRQNAM
                     ETLTGLKSSLLLGTKDNNTISAEVDSLLALLKKSQPAPIQ"
BASE COUNT         3005 a         2026 c         1786 g         3611 t
ORIGIN      
        1 agtattagtt ttatttacac aggtgcataa gaaatatatt ggaaaaattg ggggcagaca
       61 taacaaaaac ccttgtaaat caagggcttt tctgtctatt taatgctaat tgccgggatt
      121 gaaccggcga cctcatcctt accatggatg cgctctgcca actgagctaa atcagcttac
      181 ttaagaagta tactatattc agaaaaactt gtcaagtttc cttagaaatt ttccatagga
      241 aaaagccagg taagaactac ctagcttatc ttcttctatt tacttaaatc aattcgacga
      301 ccaattttac caataataat cgctccaata atcaatgaag caaattcacc gattcctgtt
      361 gtaaaccaag taaggaagaa tggtaattct gctacaatat ttaactctgc agcgatagta
      421 aacatggaaa ttgaaaagag gattgaaaag aagaaatgat cttttcgaat caatccgtta
      481 aagaggtaat ccttgctata ttttgcaaaa agccaaacac ctaaactgag gaatactaag
      541 gttgaaccac caccaacaaa gacatctagc agtccgaagc taaagaaatt agcaatcata
      601 caaccgatgg taactccgat gatgtactta ggattgtaaa aagccataaa gttcatcatt
      661 tctgaaatac gaaactgata agcaccatag ctgatggcat ttaggggcgg tgtgacagtc
      721 aaaacgacgt agatagcagc gacgattgca atatctgcaa catcacgaat agttaatttt
      781 ttcatctttt ctcctttggc ggttatccgc gtgtaatatg cttggtgaaa gaagctaagc
      841 accaagggtt gattcattca accttactag tatagcacaa tagcctgctt tatgctatac
      901 ttaaagcatg aaaaaaccta ttcaaaaatt ttttaacaat gaaatcttag cctatctctt
      961 ttttggcctt gcgacaactc tagtttcgat tctctcacga ctagtcattt atcaactaag
     1021 tcatcaggaa ctccttgcta cggccttggc aaatattatc ggtatcttat ttgcctttat
     1081 cacaaatgat acgattgtat ttaagcaaaa aaagaaaaat agacttatcc gtttagtgaa
     1141 attttctctt gctcgccttt ctacttttct gttagacttg tttttaactt ttctctttgt
     1201 aacccaattt cctcacatca tagggcaatt cgtaactgaa aacattgata agataaatgc
     1261 tattgaaaca ataattgcac aaatattcat tattatcatc aattatatct tgagcaaggt
     1321 ctatattttt agaaaataat gctccattta tgagcctttt aattgccttc tataatgatt
     1381 taggatacaa tgaaacacga aacattgaaa ggaaaacagt atgttaaaaa atctaaaatc
     1441 gttcttgctt cgaggaaatg ttattgacct tgctgtcggt gttgtcattg cctctgcttt
     1501 tggtgctatc gttacttcac ttgtaaacga cattatcact cctcttattt taaatcccgc
     1561 tttgaaagct gctaaagtcg aacgtatcgc tcaactttct tggcatggag tcggctatgg
     1621 taacttttta agtgctatta tcaattttat ctttgtgggt accgccctct tctttattat
     1681 caagggcatt gaaaaagcac agaaactgac tggcataaag aaagaaaaaa ctgccgaaaa
     1741 aaaaccaacc gaattggaag tccttcaaga aataaaagct ctccttgaga aaaaataatc
     1801 gattaaaagg atctagcgca aagctaaatc cttttttctt tactctttgg gtaacttgcc
     1861 tgctttttca agcatttttt tgataagata aggcatctta acattctccc gccctttttt
     1921 ctcaatcagt tttttcacaa attctggcat ttgtaaatct tcagattcag ctaaaatgtt
     1981 tttcgtctcg tctgaaggaa ctaactcatc aaaggtctct tcttctggga gaaattcctt
     2041 aaactcttga ttttcattga ctctaactgt attgaccaaa gcatcaatca aacgagaatc
     2101 tgtatttggc attggtggac gatggtagtt taccccaaat tcctggcata agtcataaca
     2161 ttctacatca ttgtcaaaca agacctcaat atgctcactg atgaaactaa taggtacaaa
     2221 aatataatgg tctggatgtt ctgtctgttc tctgagatac tccaaaacat ctggtttaat
     2281 ccatggaata ccaatatcac tctcactctg ccaagtgttg gtatattgtt ctgaactcaa
     2341 gcccagtttt tcagcgacta gcttgctatt ttcgaaaatt tggtctatat aaggatcacc
     2401 aaagtccaag gcaaaaatgg gcacactatg ggctgaaaag atgactttaa agctgtcttg
     2461 ctttacttct tcttttaaaa tcttagcaat ttcatctgcc caatagttta agagcgcttc
     2521 ttcctgatac cagtccttaa tgaccaaaaa ttgaatttgt ttgctttcta aaaatttttc
     2581 atagcccatg acagagtaga aagaataatg gggctccaaa atcaagcaaa tacactgttc
     2641 aattccgtct gcttccattt gaccgatcac atctggaata aagggactgg aaaacttatt
     2701 agcaaagtag acactgtatt cattccccag cctagcttct accaaggcaa cctcttgacg
     2761 ggtaattttt tgcagaggcg tgcctccaat tcgtacataa ttatcataga gagtctgaat
     2821 ctcgtggtct tggggtctca ccccacgacg aatatttgtg aaaaaatcag ctacaccttc
     2881 aaaggtaatc tcttctggtg aaccgaaggt catcattaaa attgcttttt tcatgactgc
     2941 ttccttgtga tgtttttatc aagtttattt tatcattaat taatcgataa gtaaacgcta
     3001 atatagggac attctcaatc ttctgtcttt tgtttttctc ttctttctat gatacaatgg
     3061 aaaaaataaa ttcaaaagga gtttttttat gacttatcca aatctcttgg accgcttctt
     3121 aacctacgtt aaggtcaaca cgcgctctga tgaacactct actactactc caagtacaca
     3181 gagtcaggtt gacttcgcaa caaatgtcct aattcctgaa atgaaacgtg ttggactgca
     3241 aaatgtttac tatctaccga atggttttgc tattggaacc ttgccagcca acgatccgtc
     3301 tttaacacgt aagattggtt ttatatcgca catggatact gctgatttta atgctgaagg
     3361 agtcaatcca caggtaattg aaaactacga tggtggtgtg attgaactag ggaattctgg
     3421 tttcaaactc gatccagctg acttcaagag tcttgaaaaa tatccaggac aaacgctcat
     3481 cacaacagat ggaacaagct tgctaggtgc tgatgacaag tcaggaattg ctgaaattat
     3541 gacagccatt gaatatctaa ctgctcatcc tgaaattaag cactgtgaga ttcgtgttgg
     3601 ttttggtcca gatgaagaaa tcggtgttgg tgccaataaa tttgatgcag aagattttga
     3661 tgtggatttt gcctacactg ttgatggtgg tccactaggt gaacttcagt acgagacttt
     3721 ctcagccgct ggtgctgaat tgcatttcca aggccgtaat gtccaccctg gtactgccaa
     3781 agagcagatg gtcaatgccc ttcagctagc aattgatttt cataatcaac ttccagaaaa
     3841 tgaccgacct gagttaactg aaggttacca aggtttttac catctaatgg atgtgacagg
     3901 tagtgttgag gaggtgcgtg caagctacat cattcgtgat tttgaaaaag atgcctttga
     3961 agcgcgtaaa gcatccatgc aatctatcgc tgataagatg aatgcagaac ttgggagcta
     4021 ccgtgtcact ctcaacttga cagaccagta ctacaatatg aaagaagtca ttgaaaaaga
     4081 tatgactcca attaccattg ctaaagccgt tatggaagat ctaggtatca cgcctattat
     4141 cgaaccaatc cggggtggaa cagacggctc taagatttcc tttatgggaa tcccaactcc
     4201 gaatatcttt gcaggtggcg aaaatatgca cggacgtttt gaatacgtta gccttcagac
     4261 tatggaacgt gcagttgata ccatcattgg catcgtagct tataaaggct aaaaagacga
     4321 ggtagctcag ctacttcgcc tttcttttta ttctactggt ttttcttgat ttccagtagt
     4381 tgtagaagat tctgttgttt cattttctga agttgattca gcaggtttag aatctcttgt
     4441 attgcttggt ttgttttcgt cgctagcaat ttcaatgtta gattctgcag ttgcgtttgg
     4501 ttggttctca gcactggtgt tatcactatt tgcttcagca tttcttgctg gacttgtttc
     4561 ttcacttgcg ctagcttttg actggatttg atgattcaaa actagaatag cttttgtcga
     4621 ttcaagtaaa gctgttttgt ctttactctt agcagaaagt tgatctaata atgcatccac
     4681 cttatcaaag tccgcatcag atccattatt actttctaaa taagagtgaa gcgacatgag
     4741 aatatcgtag agtttttgat agagtacaag tgtctgagaa tcttgctcag cattttcctt
     4801 ttcttgttga agggcgctag cgatacgagt caagacatct tttacctgac tgtttacttc
     4861 atccaagtct gcatcagcct tgtttgtggc agcttttaga ttttctactt cttctgccaa
     4921 ggattgtctg attccttctt catggatttg ttccaagagt tgatttacct tgctcaaaag
     4981 actttctact tcttccttgc tatctgtcgc agattattgg ttgccatcta ccatgtactc
     5041 ctaaaacagg agagttataa tccaagatta caaggcctta cagaaataag aaatccagat
     5101 aagacaatgt tcgtccaaga cgctattcgc ttcgcacagc agcacggatt caatatgctt
     5161 taattttaaa gtttaggtgt caagacctct ttttagtgtg cccaaaattt agagaagtaa
     5221 tcaatcaact aacttttatt tttttcaaac tttcagtaaa ctgacctaaa gctaactcaa
     5281 tctgtctttg tagatgcttc tgctatcagc tagaagttga tctacttttg ccaagactgc
     5341 cttctcatca aaagttccag gttgatagtt ggattgcagg gatggaatct tgtttttcaa
     5401 agccgcttca tatcccttag tttgaacctt gatgtagtga ttgtggtcgc catgaggaat
     5461 cacaaaacct tctgaatctt cacttataat tcgattggca tcaaaaccat gaccatcttc
     5521 ttcctcatga tggacatgta gtgacggatt acttaataca gaactagaag aacttcctac
     5581 ctcttccgtg ttagagtgtg atgggggatt gttaagagat gacttaggaa tatagtgata
     5641 gtgatcccca tgtcttacta tataagcatc acctgtatct ctgacaatat cattagggtt
     5701 aaagacatat gtggctgcta attcacctgc cgacaagtca ctctcaggaa tgaaatgata
     5761 gtgaccacca tgtggtacta tagtagattg aaatagaata tgagcaaatt gataagggga
     5821 ttttaaagta atttctaaca atgatttaga aactatgatg tgctattcta aattcaactc
     5881 actatatata accatcatcg gtagtataac gtccctgtaa ttttgctaca gatacttctg
     5941 cactagctcc tttatcgtct ttaccatgtt cttgtttttg gcgattgatt tcatcttttg
     6001 ttcgtacatt ttctgcatga gcttgatctt taaggtaaac ataatacttt ccatctacct
     6061 taataatata tcctccctta acctaactga cgatatcttg atctttcggc tgatagttgg
     6121 gggctttcat taatagctct tcactaaaga gcgcatcaaa aggaacttta ccattatagt
     6181 agtgataatg atcgccatga gaagttacat aaccttgatc tgtaatctta ataacaattt
     6241 gttttgcttg aattccttct ttttgactaa cctagtctgg agtcaaattt tcagtcttct
     6301 tagtgtcttt attactgttt acatatgaaa cacgattttt atctgtattg gcctgttagc
     6361 tatgttggtt cagagcataa acacacagac ttaaggaaag gataacaaca gatccagctg
     6421 ctatatattt ctttttaaat ttcataatta cctcatttct ataattattt atatgatgtc
     6481 ttcattatta aatgattaaa taaattaatt aaccaattaa ttaactagta aatattccac
     6541 ctctttttaa gttgtatgtc aagaaatttt atatattaat aataaaatga aattctccca
     6601 aagtcagagt tttatttcta acttttgaga gaacttcatt tttgattcag actttttcta
     6661 ctgctattcc ttacgctatg agatcagata aattcttttt tatcacttct ccacttggca
     6721 atcttaattc aatcgttcca tccatattga atataacact atctaagcct aatccgtaac
     6781 tagctgtaaa tttttctaat ttttcttgta caggatctac tgctggagct tcctctaatg
     6841 ctggatctaa catagggtca ctccccacat tcccttctgg attcaacatt ccattatccg
     6901 ttgagttttc tggttttaca ggtttttcgt ttggtgcctc tggtaaagaa tctgctggtt
     6961 tattttctgt tggttggttc tcaactgttc cagtagatac ttttccattt tcagatggtt
     7021 tattttcacc atttccttga ggtgcttctc ctgtaaaatc tgccatattc tttttaatga
     7081 cttctcccga tggtaaatat aattcaattg ttccgtccat attaaacaag acattttcta
     7141 gcttcatccc ataactttca gcaaattttg ctactttttc ttgtacagga tccactgtag
     7201 gaacttcttc taacgttgaa ttactagtac tattcccagt ttcagaaagt ttttcttttt
     7261 ctaccttctc actagtcttt ggttcttcta ccttttcatc aagttttgag ttttcttgtg
     7321 ctttattcct tttaaattgt ggtagaatac ttggtttatc agtttgattt tctttttcca
     7381 agataggtac ttccacaata taagtcgatt gattgtccaa ataagcattt gccatgaagg
     7441 ttacaggaat tttatttccg gccgttctgg ttgttccttg gtttaatttc ggaatcggta
     7501 atttgatttc accaacttta tagttatttt ctaaataagc atttccatga aattcatcaa
     7561 acactctgac taaagcatca gttcctttag gcactgcaaa ttgagggttc actcttaaat
     7621 aagtatcccc tgcatggaaa ggatagaaaa tcgtttgact ggccattttg taagctaaag
     7681 aggttggaac tgtaaatgta ccatcataac ttacttctgg ataatctttt gaagcgatag
     7741 tatacttaaa tgtttgtcct ggtaaataag gttgatctaa ttcaaagttt gcaatattcc
     7801 ctactccttc tccaaatact ttaccagata ctttctccaa tacttttcca tctggtgtta
     7861 ttaattttac tagcatattg atacctaatt ttttctccaa ttcaggcgga aaactaaaag
     7921 aaacgcgttt ttgaccattg gctagagtaa agttttgatt attaaacgta ctatttttta
     7981 acaaattaac aacattcgtt aattcttctc cagtataaac tttattccct tcttttttag
     8041 caactccttc ttcgggttta aacagttcat agttactgtg agaatgacca attccaaccg
     8101 gtttatgttc atcaatcgga tctgcatgat ggtgatctcc atgcggataa ataatcgcat
     8161 ttttttcttt attcacgaca atactttcac gtttgacacc atattgtttc ataatgccag
     8221 caattttttc ttcgattttt ttatctaaat ctttcatttc tttggcatta cttggataat
     8281 cctgttcatg agatgacaaa gaatctaatc cattatgact agttttaact tcctctaaat
     8341 gtttttgcgc agccttaatt tgctcttctg tcaagtcctt cttgaagaaa taatgattgt
     8401 ggtctccgtg actcatgaca aaacctgatt catcttcagc gataatacga ttagcatcaa
     8461 atccgtatcc atcttcttca tgtttctcat gtgaagttcc tggattgatt ggaagagatg
     8521 gagaaggtgt tgctagacta ttgtttggaa gagtcggttg cccaatttga tttgattttg
     8581 gaatgtaatg gaaatgatca ccatgtctta caatataagc tgtagccgtt tcttcaacga
     8641 tatcttttgg attaaaaata taaccatcag atgctgaaga gagctcctta cttgtcgtta
     8701 aagaagaagg attgcttgaa agactgccta gactagacac tacttcatta ggttttgcat
     8761 ttgtagaaac tgtagaacca gttccactga taggcaccat tctggcaatc ttttcttcta
     8821 aggcagaaag cttgctgtaa ggaataaagt ggtaatggtc gccatgcgga atcgcaactc
     8881 catttggtgt acgactgata atcttagcag ggtcaaagac caggccatct gattcactgt
     8941 aacgttgggc gctaggtgaa tcatagagtt ccttcaaaag actctggaga ttttcagatt
     9001 tatttgctgg cttgctagtt gatccttttg ctacagattg cgtgttattg tcactagctg
     9061 ttgaagaata gcttaactga ctcggttgca tattttttcc agccagatgt gctttagctg
     9121 ctgctaattc actagcagat aaatcgcttt tgggaatgta gtgatagtga cctccatgag
     9181 gaacgatata agcattaccc gtatcttcga taatatcagc tggattaaag acataaccat
     9241 catttgtcgt atatcgtccc tgagaccttg ctacagcaac attagagtta accttctcat
     9301 tatctttgac atgttcttgt ttttgacgat tgatttcatc tttagttcga acattatcag
     9361 catgagctgc atctttcagg tagacataat attttccatc gaccttgatg atataaccac
     9421 ccttgacttc attgacaata tcagcgtctt taagttgata gtttggatcc ttcatcaaga
     9481 gttcttcact aaagagggca tcataaggaa ctttcccatt atagtaatga tagtggtcac
     9541 cgtgtgacgt tacatagccc tgatctgtaa ttttgattac aatttgctca gcctgaattc
     9601 cttctttctg gctaacctgg tctggtgtca agttttcact tttctgactt gactggctgc
     9661 catccacata agagacacga ttattgtcct tattttcctg cgaacgatgc tggtttagtg
     9721 cataggcaca tagactcaag gatacgataa cagctgatcc agctgctata tattttttac
     9781 taaatttcat aaatccctca tttcaataaa tgatgaagtt ttttctcaac ttcttttact
     9841 ttattaaata gttttctaaa ccggttattt aaccatttaa ttaaccagta aatagtttac
     9901 tatttaaaat tacttttgtc aagtttctgt tacgtttttc taaaaaagag aagtaacacg
     9961 aaaggttact tctccataaa atatgctcca ttcattttac tactgtatag gagccggttg
    10021 actttttttt aacaaagcca agagactatc tacttctgct gaaatagtgt tattatcttt
    10081 cgttccgaga agaagactac tttttagacc agtcaatgtc tccatagcat tttgtctaat
    10141 actaggatct gttacttttt ctagcaaggc ctccgcatct gctatcttag cgttaataac
    10201 agaatgctct acttgaggaa tttcagcctc atctgtagta tcttcagctt cttcctctgt
    10261 ctcttccgta tcagtgcttg gtttataaag attatctgct gaaggattta aaccagcgtg
    10321 attctctttt tcatcagatt cagggtgagt tggctcactt acttcatcat gtcccttatc
    10381 ttcatcaggt ttactgtctt ggtctgcctt atttttacga acatggtc
//
LOCUS       DAVHTH010000062        10408 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.062, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000062 DAVHTH010000000
VERSION     DAVHTH010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10408)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10408)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10408
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.062"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            102..443
                     /locus_tag="VVR63_001762"
     CDS             102..443
                     /locus_tag="VVR63_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEU6129752.1"
                     /translation="MRDDIKINDRALALQDQIIEKLEKVFDTDVELDVYNLGLIYEIN
                     LDETGLCKIVMTFTDTACDCAESLPIEIVAGLKQIEGIKDIKVEVTWSPAWKITRISR
                     YGRIALGLPPR"
     gene            complement(652..2355)
                     /gene="ilvD"
                     /locus_tag="VVR63_001763"
     CDS             complement(652..2355)
                     /gene="ilvD"
                     /locus_tag="VVR63_001763"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HEU6129753.1"
                     /translation="MTELDKRHRSSIYDSMVKSPNRAMLRATGMTDKDFETSIVGVIS
                     TWAENTPCNIHLHDFGKLAKEGVKSAGAWPVQFGTITVADGIAMGTPGMRFSLTSRDI
                     IADSIEAAMSGHNVDAFVAIGGCDKNMPGSMIAIANMDIPAIFAYGGTIAPGNLDGKD
                     IDLVSVFEGIGKWNHGDMTAEDVKRLECNACPGPGGCGGMYTANTMATAIEVLGMSLP
                     GSSSHPAESADKKEDIEAAGRAVVKMLELGLKPSDILTREAFEDAITVTMALGGSTNA
                     TLHLLAIAHAANVDLSLEDFNTIQERVPHLADLKPSGQYVFQDLYEVGGVPAVMKYLL
                     ANGFLHGDRITCTGKTVAENLADFADLTPGQKVIMPLENPKRADGPLIILNGNLAPDG
                     AVAKVSGVKVRRHVGPAKVFDSEEDAIQAVLTDEIVDGDVVVVRFVGPKGGPGMPEML
                     SLSSMIVGKGQGDKVALLTDGRFSGGTYGLVVGHIAPEAQDGGPIAYLRTGDIVTVDQ
                     DTKEISMAVSEEELEKRKAETTLPPLYSRGVLGKYAHIVSSASRGAVTDFWNMDKSGK
                     K"
     gene            complement(2588..3520)
                     /locus_tag="VVR63_001764"
     CDS             complement(2588..3520)
                     /locus_tag="VVR63_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HEU6129754.1"
                     /translation="MMRSTKELRHVYRDFLLEANQSDSDIVVLEADLSSSMATHNLEK
                     DFGDRYVNVGIMEAEMVGLAAGLSIQGFRPYLHTFGPFASRRVFDQLFISLGYAQLDA
                     TVIGSDAGVTAEMNGGTHMPFEEIGLLRLIPKSIIFEATDDIQFREILNQTLDLKGLK
                     YIRTIRKAPVPVYQGGEDFSKGYIELRHGEDLVIVASGIMVAPSIRVADELSKLGYSV
                     SVIDLFRIKPIPEQIKTMLSGKTIFTVENHNQIGGIGSALCELFSDDGITKIHRMGVQ
                     ERFGQVGKMDYLLNEYGLSESNIKEKVLEIYNAR"
     gene            complement(3517..4374)
                     /locus_tag="VVR63_001765"
     CDS             complement(3517..4374)
                     /locus_tag="VVR63_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEU6129755.1"
                     /translation="MILSKNREDGLRKFATNIRLNTLRTLNHLGFGHYGGSLSIVEVL
                     AVLYGEIMPMTPEIFAARDRDYFILSKGHGGPALYSTLYLNGFFDKEFLYSLNTNGTK
                     LPSHPDRNLTPGIDMTTGSLGQGISVATGLAYGQRIRKSPFYTYAIVGDGELNEGQCW
                     EAIQFASHQQLSNLIVFVDDNKKQLDGFTKDICNPGDFVEKFSAFGFESIRVKGSDIR
                     EIYEGIVQLKQSNNSSPKCIVLDTIKGQGVQELEEMKSNHHLRPTVEERQMLTSVVER
                     LSQELEETE"
     gene            complement(4378..5724)
                     /locus_tag="VVR63_001766"
     CDS             complement(4378..5724)
                     /locus_tag="VVR63_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEU6129756.1"
                     /translation="MMKFILDIVSTPAILVALIAILGLVLQKKKLPDIIKGGIKTFVG
                     FLVVSGGAGIVQNSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATAMIMFAGM
                     VFNILIARFTRFKYIFLTGHHTLYMACMIAVILSVAGFTSLPLILLGGLALGIIMSIS
                     PAFVQKYMVQLTGNDKVALGHFSSLGYWLSGFTGSLIGDKSKSTEDIKFPKSLAFLRD
                     STVSITLSMAVIYIIVAIFAGSEYIEKEISSGTSGLVYALQLAGQFAAGVFVILAGVR
                     LILGEIVPAFKGISERLVPNSKPALDCPIVYTYAPNAVLIGFISSFVGGLVSMAIMIA
                     SGTVVILPGVVPHFFCGATAGVIGNASGGVRGATIGAFLQGILISFLPVFLMPVLGGL
                     GFQGSTFSDADFGLSGIILGILNQFGSQAGIVIGLVLILAVMFGVSFIKKPSATEE"
     gene            complement(5737..6021)
                     /locus_tag="VVR63_001767"
     CDS             complement(5737..6021)
                     /locus_tag="VVR63_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU6129757.1"
                     /translation="MLKIGTACGSGLGSSFMVQMNIESVLSDLNVSDVEVEHYDLGGA
                     DPNAADIWIVGRDLADSTSHLGDVRILNSIIDMDELRELITKLCEEKGLI"
     gene            complement(6025..8055)
                     /locus_tag="VVR63_001768"
     CDS             complement(6025..8055)
                     /locus_tag="VVR63_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEU6129758.1"
                     /translation="MFDYRALVILMTLMDHCELSLYELSVKVSLPIKEVKEGIDYLVP
                     YLANKGIVLDKKQGRYSLSNRTKQSLTDIIKSDELVLPKSTRLALIYLYTFCRLDFIS
                     NNHYQDFLKVSKNTTLSDIQSLRKIMLDNDLELGYSRAKGYTLHGSEWNKHRLAFQMV
                     SELLESSIGIWGLDYVLSSWGYSLTYDLINQVVKDYYEKLQLVPIVNQLKVYLFGLVF
                     ILCRYQRDVERVCLSETLVSPVIQDITTILLDTVVDLGIIDTVFSEDDYRYITVLLSS
                     CFEGEVDVAPVYFNQLTEAIISRMEDISLLHFKQREGLRENLRRHLIPAYYRLKFGLP
                     SSNEYVLHVKEHYPDLFELVKDSLMPLMDAIDNPIPDSETAYFVIHFGGYLKKADTLP
                     QKCYKAAIICPNGVSSSLMLKENLLALFPQIEFIGTSKIDDLQVKVSSDYDMVFSTIK
                     VETEKPNYLVSVMMTEEQAIQLVELVLKDFPNLEYGDFEIEQILNIVKRYGIITQELE
                     LRLALKNYLYQKNDRKEIVPVLEQLITKETYQVSSQKLGWKEAIRLAAKPLLDQDKIT
                     ENYPEAMIQKVEEFGPFINLGKGVAIPHARPDEGVNEIGMSMLVLEEPIYLLDNPEQE
                     VRLLICIAAIDNESHLKALSHLTTILRDKNHVQTLISSKNYDDIKMIIKQED"
     gene            8246..9253
                     /locus_tag="VVR63_001769"
     CDS             8246..9253
                     /locus_tag="VVR63_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEU6129759.1"
                     /translation="MTEKLINSKPNGVFALILIELTLVLGVFIFIMGVGSENIFGIII
                     GPLLIVIAALTHAGLKVVKPQEALVLTLFGNYTGTIKEPGFYFVNPFSVAVNPANHTR
                     LGQSGDVSTKSPFLGAKSSNGNDVNLEIGKKQISLKVMTLSNSRQKINDCLGNPVEIG
                     IAVTWRVVDTAKAVFNVDNYKEYLSLQCDSALRNIVRIYPYDVSPNVDTTGDGQADEG
                     SLRGSSEIVANRIREEIQSRVEDAGLEILEARITYLAYAPEIAAVMLQRQQASAIIDA
                     RKMIVDGAVGMVEMALERLNEGELVELDEERKAAMVSNLLVVLCGNHDAQPIVNTGSL
                     Y"
     gene            9256..9456
                     /locus_tag="VVR63_001770"
     CDS             9256..9456
                     /locus_tag="VVR63_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEU6129760.1"
                     /translation="MAEAKKKQIPLRLSTKLYAALASWAEDDFRSVNGQIEYLLTECV
                     KQRKKDGKYVSETIDEPFEIDI"
     gene            9608..9790
                     /gene="rpmF"
                     /locus_tag="VVR63_001771"
     CDS             9608..9790
                     /gene="rpmF"
                     /locus_tag="VVR63_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HEU6129761.1"
                     /translation="MAVPARRTSKAKKNKRRTHYKVTAPSVNFDETTGDYSRSHRVSL
                     KGYYKGRKIAKAASAE"
     gene            9806..9955
                     /gene="rpmG"
                     /locus_tag="VVR63_001772"
     CDS             9806..9955
                     /gene="rpmG"
                     /locus_tag="VVR63_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEU6129762.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
BASE COUNT         3377 a         2192 c         1718 g         3121 t
ORIGIN      
        1 tttcttcatt ttatcatatt tttcagaaaa ttcatcaaaa acttgccaaa ttgtcagaat
       61 tatgagaaaa tagaggatat ttatcacgtg gagggactgc tatgagagac gatatcaaaa
      121 tcaatgaccg tgctttggcc ttgcaagacc aaatcatcga aaaactagag aaagtttttg
      181 atacagatgt ggaattggat gtttacaatc taggtctgat ttatgaaatc aatctggatg
      241 aaacggggct ctgcaagatt gtcatgacct tcaccgatac tgcctgtgat tgcgccgaaa
      301 gcctgcctat tgaaatcgtg gcaggtctga aacaaatcga gggtatcaaa gatatcaagg
      361 ttgaagttac ctggtcgcct gcttggaaaa tcacacgaat cagtcgctat ggccgtattg
      421 cccttggact accacctcgt taagcaggcc aatcattttt aaagatgaaa aaagcaagcc
      481 aaaaatggct tgctttttga tactcaatga aaatcaaagg gcaaactaga aaactagccg
      541 caggttgctc aaaacactgt tttgaggttg tggatagaac tgacgaagtc agtaaccata
      601 cctacggcaa ggcgacgttg acgtgatttg aagagatttt caagtatgag tttatttttt
      661 acctgacttg tccatattcc agaagtctgt cacggctccg cgtgaagcag atgatacgat
      721 atgggcatat ttaccgagga caccacggct gtaaagtggt ggcaaggttg tttctgcctt
      781 gcgtttttca agttcttctt cggatacggc catggaaatt tctttggtat cttggtcaac
      841 cgtaacgata tcgccggtac ggagataggc aattggtcca ccatcctgag cttcaggagc
      901 gatatgtcca acaaccagac cataagtacc accagagaaa cgtccgtccg tcaagagggc
      961 caccttatct ccctgacctt taccaacaat cattgaagaa agtgacagca tctcaggcat
     1021 accaggacca cctttaggtc caacaaaacg aacaacgact acatcgccat caacgatttc
     1081 atctgtcaga acggcctgaa tcgcatcttc ttctgagtca aagaccttag ctggcccaac
     1141 gtgacgacgc actttaacac ctgatacctt ggcaactgca ccgtcaggag caaggttccc
     1201 gttcaagatg ataagcggac catccgcacg ttttggattt tcaagtggca tgataacttt
     1261 ttggcctgga gtcaagtctg caaagtcagc caagttttca gctacagtct taccagtaca
     1321 tgtgatgcga tctccgtgaa ggaaaccatt tgccaacaag tacttcataa ccgcagggac
     1381 accaccgact tcgtagaggt cttggaagac atactgacca gatggtttca agtcggccaa
     1441 gtgaggcaca cgttcttgaa tcgtattgaa gtcctcaagt gacaagtcaa catttgcggc
     1501 atgggcaatg gcgagcaagt gaagagtggc gtttgtagaa ccaccgagag ccatcgttac
     1561 agtaatagca tcttcaaagg cttcacgagt caagatatct gatggtttga gaccaagttc
     1621 caacatctta acaacagcac gtcctgctgc ttcgatatct tctttcttat cagctgattc
     1681 agctgggtga gaggatgacc ctggcaaact catccctaga acttcgatag cagttgccat
     1741 ggtattagca gtatacatac caccacaacc accagggcca gggcaggcat tacattcaag
     1801 acgtttcacg tcctcagctg tcatgtcacc gtggttccat tttccgatac cttcaaagac
     1861 agaaaccaag tcgatatctt taccatcaag atttcccggt gcaatagttc caccataggc
     1921 gaaaatagct gggatatcca tattagcaat agcaatcata gatccaggca tgttcttgtc
     1981 acagccaccg atagcgacga aggcatccac gttgtgacca ctcatagccg cctcgatgga
     2041 gtccgcgatg atgtcacgag atgttagaga gaaacgcata ccaggcgttc ccatagcgat
     2101 cccgtccgct acggtaatgg ttccaaactg tacaggccaa gcgcctgcag atttgacacc
     2161 ttctttagcc agtttcccga aatcatgcaa gtgaatgtta catggtgtat tttccgccca
     2221 agtcgaaatc actcccacaa tcgatgtttc aaagtcctta tctgtcatac cagtcgcacg
     2281 aagcatagca cggttaggtg atttaaccat gctgtcatag atgctactgc ggtgacgttt
     2341 atctaattca gtcatcttat ccctcccatt tcagttttta ctattatagc acaatttaaa
     2401 ggcaatgaac agaataaaat tcttgaattt tcagaaaatt ctatacgcat gtgaaatatt
     2461 taaaattaaa aacaacaaag cggattagtg cactttctga tgaccagaat atgcttttta
     2521 atccgctttc tttaaataac gtactgtaat ttttacagaa attctttcag ataagtgtat
     2581 ttaacatcta tcttgcatta taaatttcta gaaccttctc ttttatattc gattcactca
     2641 aaccatactc attaagaaga taatccattt tccctacttg accgaatctt tcttgaacac
     2701 ccatccgatg aatttttgtt attccatcat cagagaataa ttcacataaa gcactgccaa
     2761 ttccacctat ctgattgtgg ttttctacag taaatatagt ttttccactt aacattgttt
     2821 ttatctgttc tggtatcggt ttgattctaa ataaatctat cacacttact gaataaccta
     2881 atttagacag ttcatctgca actcgaatac ttggagcaac cattatacca gaagcaacga
     2941 ttacaagatc ttcaccatgc cttaactcaa tgtagccttt agaaaaatct tctccacctt
     3001 gatacacagg aactggagct tttctaattg ttcgaatata ttttagtcct tttaagtcta
     3061 atgtctggtt caatatttca cgaaattgga tatcatcagt tgcttcaaaa atgatcgatt
     3121 taggaattaa acgtaacaat ccaatttctt caaatggcat atgtgtccca ccattcattt
     3181 ctgcagttac tcctgcatct gatccaatca cagtggcatc caattgtgcg tatccaagag
     3241 aaataaataa ttgatcaaat actcttcgtg aagcaaaagg accaaatgta tgaagataag
     3301 gtctaaaccc ctgaatagac aagcctgctg caaggccgac catttctgct tccataatcc
     3361 caacattcac ataacggtct ccaaagtcct tttcaagatt atgagtagcc atcgaacttg
     3421 acaaatcggc ttctaagact actatatcag aatcactttg attagcctct aaaaggaagt
     3481 ctctatatac atgccgtaat tctttcgtgc ttctcatcat tctgtttcct ccaattcctg
     3541 acttaatctt tctacaactg aggttaacat ttgtctctcc tctacagtag ggcgaagatg
     3601 atgattggat ttcatttctt ccagctcttg aaccccttga cctttaatag tatctaatac
     3661 aatgcactta ggtgatgaat tatttgactg ttttaattgg acaatccctt cataaatttc
     3721 tctaatatct gaacccttga ccctaatgga ttcaaatcca aatgctgaaa atttttctac
     3781 gaaatcacct ggattacaaa tatcctttgt aaaaccatct aattgttttt tgttatcatc
     3841 aacaaataca attaagttgg ataactgttg atgagaagca aactgtatag cctcccaaca
     3901 ttgtccctca tttaactcac catctccaac aatagcataa gtataaaagg gactctttct
     3961 tattctctga ccatatgcaa gtccagttgc aacactaatt ccttgtccta aagagcccgt
     4021 tgtcatatct atgcctggcg ttagatttct atcaggatga gacggtaatt tggttccatt
     4081 tgtatttaaa gaatataaga attctttgtc aaagaaacca ttcaaataga gtgtactgta
     4141 tagagctggt cctccgtgac cttttgataa tatgaaataa tctctatctc gtgctgcaaa
     4201 tatttctgga gtcattggca ttatttcacc ataaagcact gctaaaactt ctacgataga
     4261 cagacttcct ccgtaatgtc cgaatccaag atgattcaat gttctaagag tatttaatcg
     4321 gatgttagtc gcaaattttc ttaacccatc ttctctattt ttacttaaaa tcatccctta
     4381 ttcctccgtt gcagatggct ttttaataaa ggatactcca aacataactg ctagaataag
     4441 aacaagacca atcacaatgc ctgcttgtga gccaaattga tttaatattc ctaaaataat
     4501 tcctgataga ccaaaatctg catctgagaa agttgatcct tggaaaccaa gtcctcccaa
     4561 aactggcatt aaaaagactg gaagaaaact gattaaaata ccttgtaaaa atgctccaat
     4621 agtggctcca cgaacaccac cagatgcatt cccaatgaca cctgcagtcg ctccacagaa
     4681 gaaatgaggc acaacacctg gtaagataac aaccgttcct gaagcaatca taattgccat
     4741 acttactaaa ccaccaacaa aactagagat aaatccaatt agaactgcat tgggtgcata
     4801 agtataaaca atcggacaat ccaaagcagg ttttgaatta ggtacaagac gctctgaaat
     4861 acctttaaag gctggaacaa tttcgcccaa aataaggcga acacctgcta aaataacaaa
     4921 tacccctgct gcaaattgac ctgctaattg taaagcataa actagaccac ttgtaccact
     4981 actgatttct ttttctatat attctgaccc tgcaaagata gctacaataa tgtaaataac
     5041 tgccatggat aaagtgatac taacagtact atcacgtaaa aaagctaaac tctttggaaa
     5101 tttaatgtcc tctgttgatt ttgatttgtc accgataagg ctaccagtaa aaccactcaa
     5161 ccaatatccc aaagaactga aatgacctaa agctaccttg tcatttccag ttaattgaac
     5221 catatatttt tgcacaaatg ctggggaaat actcataata ataccgagtg ctaatcctcc
     5281 tagtaagatg agaggcaagc tagtaaagcc agcaactgat aaaatgaccg caatcataca
     5341 tgccatatat agagtgtggt gccctgttaa aaaaatatat ttaaatcgag taaaacgagc
     5401 gattaagata ttgaacacca tgcctgcaaa cataatcatt gcagtagctg agccatatgt
     5461 tgttaaagct acagctacaa ttgcttcatt attcggcaca acgccagata aatgaaaagc
     5521 atgctcaaac atggtaccaa atggatttaa agaattttgt acaattcctg caccaccaga
     5581 tacaactaag aaaccaacaa aggtcttaat tccaccttta ataatatcag gtaatttctt
     5641 cttctgaaga actaatccta agattgcaat taaagctact aaaatagctg gtgtactaac
     5701 aatatccaat atgaacttca tcatgacgct agcctcctat ataagtcctt tttcttcaca
     5761 aagtttagta attaattctc gtagttcatc catatcaata atactattta agatacgaac
     5821 atctccaaga tgactagttg aatcagctag atcacgacca acaatccaaa tatcagctgc
     5881 atttggatct gctccaccta aatcataatg ttcaacttct acatccgaaa cattcaaatc
     5941 actcaataca gattcaatat tcatctgtac cataaaactt gaacctaatc ctgaaccaca
     6001 agctgtacca atttttaaca ttatctaatc ctcctgttta attatcattt taatgtcatc
     6061 atagtttttt gatgatatta aagtttgaac atgattttta tctcttaaaa ttgttgttaa
     6121 atgtgacaaa gcctttaaat gactctcatt atcaatggct gcaatacaaa tcaacaatct
     6181 tacctcttgt tctggattat ccaataaata aatcggttct tccaaaacta acattgacat
     6241 tcctatttca ttcacacctt catctggccg agcgtgagga attgctactc ccttccctaa
     6301 attaataaaa ggtccaaact cttctacttt ttgaatcatt gcctcagggt agttctcagt
     6361 tatcttatct tgatccaaaa gcggtttagc tgctaaacga atcgcctcct tccatcctaa
     6421 tttttgcgaa ctaacctgat aggtttcttt ggtaataagt tgttctagca ctggtacaat
     6481 ttcctttcta tcattttttt gataaagata attctttaac gccaatctta attccaattc
     6541 ttgtgtaata attccatatc ttttgacaat attcaggatt tgttcaatct caaaatctcc
     6601 atactctaaa ttcggaaaat cttttaacac tagttctact agttgtattg cttgctcttc
     6661 agtcatcata accgaaacta gataatttgg cttttctgtc tccaccttta tggtagaaaa
     6721 aaccatatca tagtcactac taactttcac ctgtaaatca tcaatctttg aggttcctat
     6781 aaactcaatt tgaggaaata atgctaatag attctctttt aacatcaatg aagaactaac
     6841 accattagga caaatgattg ctgctttata gcatttttga ggcaaagtat ctgctttctt
     6901 taaataacct ccgaaatgga taacaaaata tgctgtttca ctatcaggta tgggattgtc
     6961 aatagcgtcc atcaagggca tcaaagaatc tttgactaat tcaaataaat caggataatg
     7021 ttctttaaca tgcaatacat attcatttga actaggtagg ccgaacttta atctatagta
     7081 agccggtata aggtggcggc gaagattttc tctcaatcct tccctttgtt taaaatgtaa
     7141 caaagaaata tcttccattc tacttataat agcctctgtt aattgattaa agtaaaccgg
     7201 agcaacatct acttcacctt caaagcaact tgataataaa acggtgatat agcgataatc
     7261 atcctcagaa aacaccgtat ctataattcc caaatcaacc actgtatcca ataaaatagt
     7321 ggttatatct tgaataacag gagatactaa tgtctctgaa agacatactc tttcaacatc
     7381 cctttgatac ctacacagaa tgaatactaa accgaaaagg taaactttta attgattaac
     7441 aataggtact agctgtagct tctcataata atctttaact acctgattta tcaaatcata
     7501 agttaatgaa tacccccaac tggataaaac ataatccaaa ccccaaatcc ctatggagga
     7561 ttccagcaac tcactaacca tttgaaaagc taagcggtgc ttattccact ctgaaccgtg
     7621 taaagtataa ccttttgctc tactgtaccc tagctccaaa tcattatcta acataatctt
     7681 tcttaatgat tgaatatcag ataaggttgt attcttactt actttcaaaa agtcttggta
     7741 atgattattc gatataaaat ctaatcggca aaaagtgtaa agatagatta aagctaagcg
     7801 agtcgacttt ggtaaaacca attcatccga cttaataata tctgtcaaag actgcttcgt
     7861 acgatttgat aaactatagc gaccttgttt tttatccagc actatccctt tattagctag
     7921 ataaggcact aaataatcta ttccttcttt gacttccttt ataggtaagc tcaccttaac
     7981 agataattca tataatgata gctcacaatg atccatcaaa gtcatcaaaa taactagtgc
     8041 tctataatca aacatttctc ttcctttcta actacaatta tagtgtaaaa attataagaa
     8101 taaaagagta tttgagcaca atataatctc accttttaaa agaaattatt gggctgaaag
     8161 tttttagtga ttattttcaa ctttctattg acttttaaaa acaaagtgat atcatttaga
     8221 tatcaaataa tgggaggtca ttcttatgac tgaaaaacta atcaattcaa aaccaaatgg
     8281 tgtattcgca ttgattctca ttgaattgac gctcgtactt ggtgtcttta tatttataat
     8341 gggggttggt tcggaaaaca tttttggaat tattatcgga cctttactaa tcgtaattgc
     8401 agcgctaact catgctggtt taaaagttgt caaacctcag gaggctctgg ttctgacact
     8461 ctttggtaac tatacaggta ccatcaaaga acctggcttt tactttgtca atcccttcag
     8521 cgtagcagtc aaccctgcaa accacactcg acttggacaa agtggtgatg ttagcacaaa
     8581 atctcctttt ttaggagcta aatcatcaaa tggcaatgat gtaaatcttg aaattggcaa
     8641 gaaacagatt tccctcaaag tcatgacctt gagcaattct cgtcaaaaaa tcaatgattg
     8701 cttaggaaac cctgtagaaa tcggtatcgc ggtaacttgg agagttgtcg ataccgctaa
     8761 ggcagtcttc aacgttgata actacaaaga atatctttca ctgcaatgtg atagcgccct
     8821 ccgtaatatt gtccgcatct atccttacga tgtgtctcct aatgtggata ctacgggtga
     8881 cggacaagca gatgaaggta gtctccgtgg ctctagcgaa attgttgcta accgtattcg
     8941 tgaagaaatc caaagtcgtg ttgaggatgc tggcttggaa atccttgaag cacgtatcac
     9001 ttacctagct tatgctccag aaattgctgc cgttatgctt caacgccaac aagcatctgc
     9061 cattattgat gcacgtaaga tgattgtaga tggtgctgta ggaatggttg aaatggcact
     9121 agaacggctc aatgaagggg aattggtaga acttgacgaa gaacgaaaag ctgccatggt
     9181 ttcaaatctc cttgtcgttc tttgtggcaa tcatgatgca caaccaattg tcaacacagg
     9241 aagtctttac taaagatggc tgaagctaaa aaaaagcaga tcccccttcg actctcaaca
     9301 aagttatacg ctgcactcgc atcatgggca gaagacgact ttcgttcagt caatggccaa
     9361 atcgaatatc tcctcacaga gtgtgtcaag caacggaaga aagacggaaa atacgtatca
     9421 gaaaccattg acgaaccatt tgagattgat atttaacacc ttctcctgtc tgccgtgtcg
     9481 gataggagaa ttttttcatc tttttttgtc aagtaacttt actttacaaa aaaaatgtgt
     9541 tatcctagta tggttgatga aaatcagtag attgaatcga atataaatac ctaaaggaga
     9601 aatcaaaatg gcagtacctg cacgtcgcac ttcaaaagcg aagaaaaaca aacgtcgtac
     9661 acactacaaa gtaacagctc catctgtaaa ctttgacgaa actactggag attactcacg
     9721 ttctcaccgt gtatcactta aaggatacta caaaggacgt aaaatcgcta aagctgcatc
     9781 agctgaataa tagaagggag ataccatgcg cgtaaatatt acacttgaac acaaagaatc
     9841 tggtgaacgc ttgtacctta cttctaaaaa caaacgtaac actccagacc gccttcaatt
     9901 gaagaaatac tcaccaaaac ttcgcaaaca cgttgtgttt acagaagtta agtaagcatt
     9961 caatacgaat caatacagaa gaaaaacgct tgatcagcgt tttttctttt tgttaatttc
    10021 actatattgc aagggaaatc attcgaatga ctacattttt cactaccttt tttgaaataa
    10081 gaatacggat tcggacgatt aaaagtaaga gaaactcaaa tgtaagttgg ggttcctttt
    10141 ttgtatattt ttcaaataac gcctctacac tatttgtagc aaattcacca actacagttg
    10201 tatcttagtt aaaataagtt agaatatgta agtgagtacc agatatacca agacatcgtc
    10261 accatctaag gtatattcaa aatacaaaag ttgaccaact agatttctga atatccttat
    10321 atatccattc ttaaaattgg tttaaatagc gtagtctttt aaactagttt tgagaatcca
    10381 aaaaatcttc ctacatatgt aagaagat
//
LOCUS       DAVHTH010000063        10312 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.063, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000063 DAVHTH010000000
VERSION     DAVHTH010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10312)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10312)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10312
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.063"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            1..201
                     /locus_tag="VVR63_001773"
                     /pseudo
     CDS             1..201
                     /locus_tag="VVR63_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558102.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            299..511
                     /locus_tag="VVR63_001774"
                     /pseudo
     CDS             299..511
                     /locus_tag="VVR63_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            411..857
                     /locus_tag="VVR63_001775"
     CDS             411..857
                     /locus_tag="VVR63_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEU6129763.1"
                     /translation="MRKHGLISKSTSKGYYQVAIPFMRLFCLVLVSIDYINCLSETTD
                     KNWHKSDRIFVTNTGKPVHSSILSKSLQRANERLKKPIPKHLSPHIFRHTTISILSEN
                     KIPLKTITDRVGHSDSEVTTSIYTHVTKNMKDEAINVLDKVMKKIF"
     gene            complement(995..2299)
                     /gene="eno"
                     /locus_tag="VVR63_001776"
     CDS             complement(995..2299)
                     /gene="eno"
                     /locus_tag="VVR63_001776"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HEU6129764.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYGGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMILPVGAPTFKEALRYGAEIFHALKKILKSRGLETAVGDEGGFAPRFEGTEDG
                     VETILAAIEAAGYVPGKDVFIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQID
                     YLEELVNKYPIITIEDGMDENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLARGIQE
                     GAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQ
                     IKTGSLSRTDRIAKYNQLLRIEDQLGEVAEYRGLKSFYNLKK"
     gene            2463..2909
                     /locus_tag="VVR63_001777"
     CDS             2463..2909
                     /locus_tag="VVR63_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HEU6129765.1"
                     /translation="MTDLSKQLLEKAHGGLKINPDEQRRYLGTFEERVLGYVDIDTAN
                     SPQLEKGFLFILENLQEKAKPLFVKISPTIEFDKQVFYLKEAKETDSQATIVSEEHIT
                     SPFGLVIHSNAPVQVEEKDLRLAFPKLWEVKKEEPAKTSLWKKWFS"
     gene            complement(2906..3709)
                     /locus_tag="VVR63_001778"
     CDS             complement(2906..3709)
                     /locus_tag="VVR63_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HEU6129766.1"
                     /translation="MKIVIAPDSFKESLTAQQVAEAIKRGFQQSIADVECLLCPVGDG
                     GEGTVDAIRHSLDLKEKWIQVTAPFGQKEAMRYFQKGELALFEVADLVGLGKIPLEKR
                     NPLQIQTCGIGELILHLISKGIKDIYIGVGGTASNDGGLGIAAGLCAFAQASIVSGID
                     TCLDLINFDKKVSDADLVVVGEGRLDSQSFAGKAPIGVAKRTPVGVPVIAICGSLAED
                     LPPLPFENIQAVFSILEKSEPLEDSLKNASLYLERTAANIGHLLNMCKI"
     gene            complement(3718..4047)
                     /locus_tag="VVR63_001779"
     CDS             complement(3718..4047)
                     /locus_tag="VVR63_001779"
                     /inference="COORDINATES: protein motif:HMM:NF012905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HEU6129767.1"
                     /translation="MERLAKSLGIAYFTANQLEVKEGLLTGKLVGQIISPQVKKETLE
                     KWRKKLKLSKERTVAIGDGVNNLLMLKSAELGIAFCSKEMLKKEIPHHVDKRDFLEVL
                     PLIDCLE"
     gene            complement(3992..4363)
                     /locus_tag="VVR63_001780"
     CDS             complement(3992..4363)
                     /locus_tag="VVR63_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family phosphatase"
                     /protein_id="HEU6129768.1"
                     /translation="MSQVKGLCVLDVDGTLILEEVIDLLGREAGHEAEISQITSRAMR
                     GELVFESSLRKRVSLLEGLPILVFDNVFNSIHLSLNVPEFISILQKNGILVGLVSGGF
                     TPIVGEISKIPWYCLFHCQPA"
     gene            complement(4422..5855)
                     /gene="glgA"
                     /locus_tag="VVR63_001781"
     CDS             complement(4422..5855)
                     /gene="glgA"
                     /locus_tag="VVR63_001781"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HEU6129769.1"
                     /translation="MKILFVAAEGAPFSKTGGLGDVIGALPKSLVKAGHEVAVILPYY
                     DMVEAKFGNQIEDVLHFEVSVGWRRQYCGIKKTVLNGVTFYFIDNQYYFFRGHVYGDF
                     DDGERFAFFQLAAIEAMERIDFIPDLLHVHDYHTAMIPFLLKEKYCWIQAYEDIETVL
                     TIHNLEFQGQFSEGMLGDLFGVGLERYADGTLRWNNCLNWMKAGILYANRVSTVSPSY
                     AHEIMTSQFGCNLDQILKMESGKVSGIVNGIDADLYNPQTDALLDYHFNQEDLSGKAK
                     NKAKLQERVGLPVRADVPLVGIVSRLTRQKGFDVVVESLHHILQEDVQIVLLGTGDPA
                     FEGAFSWFAQIYPGKLSANITFDVKLAQEIYAACDLFLMPSRFEPCGLSQMMAMRYGT
                     LPLVHEVGGLRDTVRAFNPIEGSGTGFSFDNLSPYWLNWTFQTALDLYRNHPDIWRNL
                     QKQAMESDFSWDTACKSYLDLYHSLVN"
     gene            complement(5852..6991)
                     /gene="glgD"
                     /locus_tag="VVR63_001782"
     CDS             complement(5852..6991)
                     /gene="glgD"
                     /locus_tag="VVR63_001782"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HEU6129770.1"
                     /translation="MKIDKYSAILGNTVGFHDMSTLTDHRPVASLPFGGKYRLIDFPL
                     SSLANAGVRSVFGIFQQDNISSVFDHIRSGREWGLSTLLSHYYLGIYNTRVESSTVGK
                     EYYQQLLTYLKRSGSNQTVALNCDVLINIDLNQVFHLHSTTKEPITVVYKKLAKKDIS
                     EVNAILDVDETDHVLSHKLFDSKSTAETFNMSTDIFVVDTPWLIEHLEEEAKKEHPEK
                     LRYVLRDLAVKEGAFAYEYTGYLANIHSVKSYYQANIDMLESQKFYSLFSPNQKIYTK
                     VKNEEPTYYANTSKVSTSQFASGSIIEGQVANSVLSRNIHVHKDSLVKDSLLFPRVVI
                     GEGAQVEYAILDKGVEVELGVVIRGTAEHPVVVKKGAKVTEDIHS"
     gene            complement(6981..8123)
                     /locus_tag="VVR63_001783"
     CDS             complement(6981..8123)
                     /locus_tag="VVR63_001783"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000787267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HEU6129771.1"
                     /translation="MKNEMLALILAGGQGTRLGKLTQSIAKPAVQFGGRYRIIDFALS
                     NCANSGIHNVGVVTQYQPLALNNHIGNGSSWGLDGINSGVSILQPYSASEGNRWFEGT
                     SHAIYQNIDYIDSVNPEYVLILSGDHIYKMDYDDMLQSHKDNNASLTVAVLDVPLKEA
                     SRFGIMNTDANNRIVEFEEKPAQPKSTKASMGIYIFDWQRLRNMLVAAEKSKVGMSDF
                     GKNVIPNYLESGESVYAYEFSGYWKDVGTIESLWEANMEYISPENALDSRNRQWKIYS
                     RNLISPPNFLGANAHVEDSLVVDGCFVDGTVKHSILSTGAQVREGAEVLDSVIMSGAI
                     IGQGAKIKRAIIGEGAIISDGVEIDGTDEVQVVGYNEVVGVATDED"
     gene            complement(8113..10041)
                     /gene="glgB"
                     /locus_tag="VVR63_001784"
     CDS             complement(8113..10041)
                     /gene="glgB"
                     /locus_tag="VVR63_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
                     /protein_id="HEU6129772.1"
                     /translation="MDNREALKTFMTGENFYLQHYLGAHREELNGEHGYTFRVWAPNA
                     QAVHLVGDFTNWIENQIPMVRNDFGVWEVFTNMAQEGHIYKYHVTRQNGHQLMKIDPF
                     AVRYEARPGTGAILTELREKKWKDGLWLARRKRWGFEERPVNIYEVHAGSWKRNSDGS
                     PYSFAQLKDELIPYLVEMNYTHIEFMPLMSHPLGLSWGYQLMGYFALEHAYGRPEEFQ
                     DFVEECHTHNIGVIVDWVPGHFTINDDALAYYDGTPTFEYQDHNKAHNHGWGALNFDL
                     GKNEVQSFLISCIKHWIDVYHLDGIRVDAVSNMLYLDYDDAPWTPNKDGGNLNYEGYY
                     FLQRLNEVIKLEYPDVMMIAEESSSATKITGMKEIGGLGFDYKWNMGWMNDILRFYEE
                     DPIYRKYDFNLVTFSFMYVFKENYLLPFSHDEVVHGKKSMMHKMWGDRYNQFAGLRNL
                     YTYQICHPGKKLLFMGSEYGQFLEWKSEEQLEWSNLEDPMNAKMKYFTSQLNQFYKDH
                     RCLWEIDTSYDGIEIIDADNRDQSVLSFIRKGKKGEMLVCIFNMVPVERKDFTIGLPV
                     AGIYEEVWNTELEEWGGVWKEHNQTVQTQEGLWKDYEQTLTFTLPAMGASVWKIKRRL
                     KSTKTVTNKNQKGVENEK"
BASE COUNT         3150 a         2261 c         1812 g         3089 t
ORIGIN      
        1 tactatgaac aagacccaga aaaagtagcc ttatttctta agaattttaa tagtttaaag
       61 cacctagcac aggtctaaca aatgaatggt gagttaatcg ctccaatgac ttacgaagag
      121 acgatgacga gcgacttttt tgaagcttgg tttcagaaat ttctcttacc aacattaacc
      181 gcaccattgg ttattatatt aaaacgaagt aagaatagga caaatcgatc aggacagtaa
      241 aatctaattc taacaatgtt ttagaagtag aggtgtacta ttctagtttc aatctactat
      301 attaatggac aatgcaagat tccatagaat ggggaagcta gaactcttgt gtgaagagtt
      361 tgggcataaa cttttacctc ttcctcccta ctcgcctgag tacaatctta ttgagaaaac
      421 atgggctcat atcaaaaagc acctcaaaag ggtattacca agttgcaata ccttttatga
      481 ggctcttttg tcttgttctt gtttcaattg actatataaa ttgtctaagc gaaacaaccg
      541 ataagaattg gcacaaaagc gaccgtattt ttgttaccaa tacaggaaaa ccagttcata
      601 gttctatctt gagcaagtct ctccagcgag caaacgaacg ccttaaaaaa ccaattccca
      661 aacatctgtc ccctcacatc ttcagacaca ccactattag catcttatca gaaaataaaa
      721 ttcctttaaa aacaatcacg gacagggttg gtcattccga ctctgaagtc actacttcca
      781 tctacaccca cgtcacaaag aacatgaaag atgaagcaat caatgtactg gataaagtta
      841 tgaaaaagat tttttaaaaa gttttgtccc ttttttgtcc tctaaataca aaaatagccc
      901 ttcggataaa atccgagggg ctagaaacgt tgttaaatca acggccgaac ttttgaattt
      961 catggttcgg gataaaatag ttcactgaac tattttattt tttaaggttg tagaatgatt
     1021 tcaatccacg atattcagct acttcaccaa gttggtcttc gatacgaagc aattggttgt
     1081 atttagcgat gcggtctgta cgtgaaagtg aaccagtctt gatttgtcct gcgttagttg
     1141 caactgcaat atcagcgatt gttgaatctt cagtttcacc tgaacggtgt gatacaacag
     1201 cagtgtaacc agcttcttta gccatttcga tagcttcaaa agtttcagta agagtaccga
     1261 tttggttaac tttgataagg attgagttag cagcaccttc ttggatacca cgtgcaaggt
     1321 agtcagtgtt tgttacgaag aagtcgtcac caacaagttg tactttctta ccaagacgtt
     1381 cagtaagagc tttccaacca tcccagtcgt tttcatccat accatcttca atagtgatga
     1441 ttgggtattt gttaaccaat tcttcaaggt agtcgatttg ttctgcagat gtacgaacag
     1501 cagcaccttc accttcaaat ttagtgtagt cgtaaacttt acgttcttta tcgtagaatt
     1561 ctgatgaagc acagtcaaat ccgataaata cgtctttacc tggtacatat ccagcagctt
     1621 caatcgcagc aaggatagtt tcaacaccat cttcagttcc ttcgaaacga ggagcgaatc
     1681 caccttcgtc acctacggca gtttccaaac cacgtgattt aaggattttc ttaagagcgt
     1741 ggaagatttc agcaccgtaa cgaagggctt ctttaaatgt tggcgcacca actggcaaga
     1801 tcatgaactc ttggaaagcg attggagcgt cagagtgaga accaccgttg atgatgttca
     1861 tcattggagt tggaagaact ttagtgttga atccaccaag gtagctgtaa agtgggattt
     1921 caaggtagtc agcagcagca cgagctacag cgatagacac accgaggatt gcattcgcac
     1981 ccaatttacc tttgttagga gtaccgtcaa gtgcaatcat agcacggtca atagcttgtt
     2041 gatcacgtac atcgtagcca atgatagctt cagcaatgat gttgtttacg ttgtcaacag
     2101 ctttttgtgt accaagacca ccgtaacgag atttgtcacc gtcgcgaagt tcaactgctt
     2161 cgtgttcacc agtagaagct cctgatggaa ccataccacg tccgaaagca cctgattcag
     2221 tgtaaacttc tacttcaagt gttgggttac cgcgtgagtc taggacttcg cgagcgtaaa
     2281 catcagtaat aattgacatt ttttactctc cttatgagtt aaatttttta cacctctata
     2341 ataccttaaa acccctcctt tttcaagaaa aaacgttatc tttgtgcaac ttttccttaa
     2401 ctttataaag taatcgcttt cttttgtctg ttttattcta acttttatga tatactgttt
     2461 tcatgacaga tttatcaaaa caattacttg aaaaagctca tggtgggtta aaaataaatc
     2521 cggatgagca aagacgctat cttggtactt ttgaggaaag agttcttgga tatgtagata
     2581 ttgacacagc aaatagccct cagttagaaa aaggcttttt atttatttta gaaaaccttc
     2641 aggaaaaagc aaagccacta tttgtgaaga tttcaccaac tatcgaattt gataagcaag
     2701 ttttctactt aaaagaagca aaagaaactg atagtcaagc caccatagta tctgaagagc
     2761 atattacttc tccttttggc ctggttattc atagcaatgc accagttcaa gtagaagaaa
     2821 aagaccttcg acttgctttt ccaaaacttt gggaagttaa aaaggaagaa ccagccaaaa
     2881 catccttatg gaagaaatgg tttagctaaa tcttgcacat atttaataag tgcccaatat
     2941 tggcagccgt gcgctccaga tagagactgg catttttcaa actatcttct aaaggttcac
     3001 ttttctccaa aatagaaaag acagcttgga tattttcaaa tggtagggga ggtaaatctt
     3061 cagcaagact accgcaaata gcaataacag gaactccaac aggggttctt tttgcaacac
     3121 ctataggcgc tttcccagca aagctttgac tatcaagtct tccttctcca acaacaacca
     3181 agtcagcatc tgaaactttc ttatcaaagt tgattaagtc caagcaggta tcaattccag
     3241 acacgatact tgcctgagca aaggcacaca aaccagcagc aatccccagt cctccatcat
     3301 tactggccgt gccaccaaca ccgatataaa tatctttaat ccctttagaa atgagatgga
     3361 gaatcaactc tccaatacca caagtttgga tttgaagtgg atttcgtttc tctagcggaa
     3421 tttttccaag accaaccaag tcagctactt caaatagtgc cagttcccct ttttgaaaat
     3481 agcgcatggc ttctttttgt ccaaaagggg ctgtcacttg gatccatttt tcttttaggt
     3541 caagagaatg tcggatagca tctacagtac cttctccccc atcaccaaca gggcagagga
     3601 gacattctac atctgctatc gattgttgga agcctctttt tattgcttca gctacctgtt
     3661 gagctgtcaa gctttcctta aacgaatccg gtgcaattac aatcttcata ttttccctca
     3721 ttctaaacag tcaatcaaag gaagaacttc taaaaaatcc ctcttgtcaa catgatgtgg
     3781 tatttctttt ttgagcattt ctttggaaca aaaggcgatt cctaactccg ccgacttcaa
     3841 cattaataga ttattaaccc catcaccgat tgccaccgtt ctttctttag aaagttttag
     3901 tttctttctc catttttcca gagtttcttt tttgacctgg ggacttataa tttgtccaac
     3961 taattttcct gttaaaagac cttctttgac ttcaagctgg ttggcagtga aataggcaat
     4021 accaagggat tttgctaatc tctccaacta ttggtgtaaa tccaccagac accagaccaa
     4081 ctaggatgcc attcttttgg agaatagaga tgaactctgg gacatttagc gatagatgaa
     4141 ttgagttgaa gacgttatca aagaccaaaa taggaagacc ttccaacaag gacactcttt
     4201 ttcttaaact gctttcaaag accaactctc ctcgcattgc tcgacttgta atctgcgaaa
     4261 tttccgcctc atgacctgcc tctctcccta aaagatcaat cacttcttct aggattaagg
     4321 ttccatctac atccaaaaca cacaagcctt ttacttgaga catcagttct cctctctaaa
     4381 cagcctaaaa atcgtatgaa gtcatcatac gattttatct attaattaac taaactatgg
     4441 tacaagtcaa ggtatgactt gcaggctgta tcccatgaga agtcactctc catagcttgt
     4501 ttttgtaggt ttctccaaat gtctggatgg tttctataca agtccaatgc tgtttggaaa
     4561 gtccaattta accaataagg agatagattg tcaaagctaa agccagtacc gcttccttcg
     4621 attggattga aagcgcgaac tgtatctcgc aagcctccaa cttcatggac caatggcaag
     4681 gttccataac gcatagccat catttgagac aagccacacg gttcaaaacg acttggcatg
     4741 aggaagaggt cacaagcagc gtagatttcc tgagcaagtt tgacatcaaa agtgatattt
     4801 gctgatagct tgcctgggta aatctgagca aaccatgaga aagctccttc aaaggctgga
     4861 tcgccagttc ccaaaagaac aatctgaaca tcttcttgca agatatggtg aagactttcg
     4921 accaccacat caaaaccttt ttgacgtgtc aaacgagaaa caattcccac cagtggaacg
     4981 tctgctctaa caggcaagcc aactctttct tgcaattttg ccttattttt ggctttccca
     5041 gacaaatctt cctgattgaa atgatagtct aaaagagcat ccgtctgagg attataaaga
     5101 tcagcatcaa tcccattcac gataccagat actttaccag actccatttt aagaatctga
     5161 tccaaattac atccaaactg actagtcata atttcatgag catagctagg tgaaacggtt
     5221 gaaacacggt tcgcatagag aatacctgcc ttcatccagt tcagacagtt gttccatcga
     5281 agggtgccat cagcgtaacg ttcaaggcca actccaaaca aatcacccaa cattccttct
     5341 gaaaattgtc cttggaattc taaattatga atggttaaaa ctgtttcaat gtcctcatag
     5401 gcttgaatcc aacagtattt ttccttcaac aagaaaggaa tcatagctgt atggtagtca
     5461 tgaacatgga gaagatcagg aataaagtca atcctttcca tagcctcaat ggcagccagt
     5521 tggaaaaagg caaagcgttc tccgtcatca aaatcaccgt aaacatgacc acggaagaaa
     5581 taatattgat tgtcaataaa gtagaaggtt acaccattta atactgtttt cttaattcca
     5641 caatactgtc tacgccaacc aacgctcacc tcaaaatgaa gcacatcttc aatctgattt
     5701 ccaaatttag cctctaccat atcatagtag ggtaaaatca ctgcaacttc gtgcccagct
     5761 tttaccagtg attttggaag agcgccaatg acgtctccca aaccacctgt ttttgaaaag
     5821 ggtgcaccct ctgctgctac aaataaaatt ttcatgaatg aatatcctct gttactttag
     5881 cacctttctt aaccacaact ggatgttctg cagttcctcg aatcacaaca ccaagctcaa
     5941 cttcaacccc tttgtccaag atagcatatt cgacctgagc cccttctcca ataacaacac
     6001 gagggaagag caggctatct ttaaccaagc tatccttatg gacatgaata ttacgtgata
     6061 gaacagaatt agctacttga ccttcaataa tactaccaga ggcaaactga gaagtgctta
     6121 ccttagatgt attagcatag taagttggct cttcgttttt gacctttgta taaatctttt
     6181 ggtttggtga gaaaagagaa tagaattttt gtgattcaag catatcgata ttcgcttgat
     6241 aataagattt aacagagtga atattggcta gatagcccgt gtactcgtag gcaaaagctc
     6301 cctcttttac agccaaatcc cgtaaaacat agcgcaattt ctctggatgt tcttttttag
     6361 cttcttcttc caagtgttca atcaaccaag gtgtatcaac gacaaagata tctgtagaca
     6421 tattgaacgt ttcagctgtt gacttgctat caaagagttt atgagaaaga acatggtctg
     6481 tttcatctac atccaagatt gcatttactt ctgaaatatc tttcttagct agttttttat
     6541 aaactacagt gataggctct tttgttgtac tatgtaggtg gaaaacttgg ttcaaatcaa
     6601 tgttaataag aacatcgcag ttgagggcaa ccgtttggtt tgagccagaa cgtttcaaat
     6661 aagtaagaag ctgttggtag tattcttttc caactgtact actttctaca cgggtattgt
     6721 aaattcctag atagtaatgg ctaagaaggg ttgataagcc ccactcgcgc cctgaacgaa
     6781 tatggtcaaa gactgagctg atattatcct gctggaaaat accaaagaca ctacgaacac
     6841 ctgcattagc aaggcttgaa agtgggaagt caatcaaacg atatttccca ccaaatggca
     6901 aacttgctac tggacggtgg tccgtcaatg tcgacatatc gtgaaaacca actgtatttc
     6961 ctaaaatggc agaatattta tcaatcttca tctgttgcta cccccactac ttcattatat
     7021 cctacaactt gtacttcatc tgttccatca atttcgacac cgtcagaaat aatcgcacct
     7081 tcaccaataa tggcacgttt aatcttagct ccttgaccaa tgatagctcc actcatgata
     7141 actgaatcaa ggacttccgc tccttcgcga acttgcgcgc ctgttgaaag gatagaatgt
     7201 ttaacagttc catcaacgaa acatccgtct acaactaatg agtcttccac atgagcattt
     7261 gccccgagga agtttggtgg tgaaatcaag tttcttgagt aaatcttcca ttgacggtta
     7321 cgactatcca aggcattttc tggagaaata tactccatgt tcgcttccca aagtgactca
     7381 atagtaccaa catctttcca ataaccacta aattcataag cataaacact ttcacctgac
     7441 tcaaggtaat ttggaatgac atttttacca aagtctgaca tgccaacctt gctcttttca
     7501 gcagcgacta acatattacg aaggcgttgc caatcaaaaa tgtagattcc catagaagct
     7561 tttgtagatt taggttgagc tggtttttct tcaaattcaa caatacgatt gttagcatct
     7621 gtgttcatga taccaaaacg gcttgcttct ttaagaggga cgtctaaaac tgctactgtc
     7681 aagctggcat tattatcctt atgagactgg agcatatcat catagtccat tttgtagatg
     7741 tgatccccag acaaaatcaa gacatactca ggattgacac tgtcgatata gtcgatattt
     7801 tggtaaatag cgtgactagt cccctcaaac caacgatttc cttcacttgc agaataaggt
     7861 tgaagaatag agacacctga attaataccg tctagtcccc agcttgaacc attcccaata
     7921 tggttgttga gagcaagtgg ttgatactgt gtaacgaccc caacattatg aatccctgag
     7981 ttggcacagt ttgatagggc aaagtcaatg atacggtagc gcccaccaaa ttgcacagct
     8041 ggttttgcga tgctttgagt gagtttaccg agacgagttc cttgcccacc agcaagaatc
     8101 aaagctaaca tttcattttt cattttctac tcctttttgg tttttatttg tgacggtttt
     8161 agtagatttc aagcgacgtt tgattttcca tacacttgct cccatagccg gtagggtaaa
     8221 ggttaaggtc tgctcataat ctttccatag tccttcttgc gtttgaacag tttgattatg
     8281 ttctttccaa acgcctcccc actcttccaa ctcagtattc catacttctt cgtaaattcc
     8341 tgcaacgggt agtccgattg taaaatcttt ccgctcaaca ggtaccatgt taaagataca
     8401 gactaacatt tctccctttt tacccttacg aataaaggaa agaacactct ggtctcgatt
     8461 atccgcatca atgatttcaa taccatcata gctggtatcg atttcccaca gacagcgatg
     8521 atctttgtaa aactggttta gctgagaagt gaaatacttc atcttagcat tcattgggtc
     8581 ttctaggtta gaccattcca actgttcttc agatttccat tctaggaatt gaccgtattc
     8641 gctacccatg aagagcaatt tcttaccagg atgacaaatt tggtacgtat agagattgcg
     8701 caagcctgcg aattgattgt aacgatctcc ccacatctta tgcatcatac tcttcttgcc
     8761 atgaaccact tcatcgtgcg agaatggcaa gagataattc tccttgaaaa catacataaa
     8821 gctgaaagtc accaggttaa agtcatattt acgatagatc ggatcttctt cgtagaaacg
     8881 gaggatatca ttcatccagc ccatgttcca tttgtagtca aatcctagac caccaatctc
     8941 tttcattccc gtaatcttgg tcgcagacga actttcttct gcaatcatca tcacatctgg
     9001 atattctaac ttaataacct cattcaagcg ctgaaggaaa taataacctt catagttgag
     9061 atttccgcca tctttattag gtgtccatgg agcatcatca tagtccaaat agagcatgtt
     9121 gctaacagca tccacacgaa taccatccaa atgatagaca tcaatccaat gcttaatgca
     9181 agaaattaag aaggactgga cttcattttt tccaaggtca aaattaaggg caccccaacc
     9241 atggttatga gccttattat ggtcttggta ttcaaaagtc ggtgtcccat cataataggc
     9301 taaggcatca tcgttgatgg taaagtgacc tggtacccag tccacaataa ccccaatatt
     9361 atgggtatga cactcctcga caaaatcttg aaactcctct ggtcggccat aagcatgctc
     9421 taaagcgaag taacccataa gctgataccc ccaactcaag cccaaaggat gggacatcaa
     9481 gggcataaac tcaatatgag tatagttcat ttcaacgaga taaggaatga gttcatcctt
     9541 gagctgggca aaactataag gactgccatc agaatttctt ttccatgatc cagcgtgaac
     9601 ttcataaata ttgacaggac gctcttcaaa gccccaacgt tttcttcgtg ccagccaaag
     9661 tccatccttc catttcttct cacgaagctc tgttaagatt gcccctgttc ctggacgagc
     9721 ctcatacctg acagcaaaag ggtcaatctt catcagttga tgaccatttt gacgtgtgac
     9781 atgatatttg taaatatgcc cttcttgagc catattggta aagacttccc agaccccaaa
     9841 atcatttctt accattggaa tctgattttc aatccagttg gtaaaatcac caaccaagtg
     9901 aacagcctga gcattaggtg cccaaacacg gaaggtatag ccatgctctc catttagttc
     9961 ttccctatgt gctcctagat aatgttggag ataaaaattt tcacccgtca taaaggtttt
    10021 taatgcttct ctattatcca tatactcccc ttctcctgta agcgttttct atgtttttat
    10081 tatactacct ttttagagaa gattcaagta aattactata cttctttaat tattttgaaa
    10141 atctacaaca agttcactta ctcgttcaat tgtaaatcaa tattttttca aaaaattgcg
    10201 aaaactcctt tctttttcta ctatagtgaa atgaaataaa acatgcgcaa atcgattaag
    10261 gaatttaatc taatttctaa caatgtctta gaaatcaaag tgtactattt ta
//
LOCUS       DAVHTH010000064         9884 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.064, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000064 DAVHTH010000000
VERSION     DAVHTH010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9884)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9884)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9884
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.064"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            108..407
                     /locus_tag="VVR63_001785"
                     /pseudo
     CDS             108..407
                     /locus_tag="VVR63_001785"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(685..1455)
                     /locus_tag="VVR63_001786"
     CDS             complement(685..1455)
                     /locus_tag="VVR63_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HEU6129773.1"
                     /translation="MVEIIYFLIIIIASGLGSISGMGGGIIIKPLMDSFGYHSVSDIA
                     FYSSFSVFIMAIISTTKRFSQSKEIKWRLIFTVSFSSVLGGFLGHLIFQVLLSQLSVR
                     LVSIVQMILLFVMLLVSFVLTDFKKTYQFDKIGFYMICGLLLGLISSFLGIGGGPLNV
                     SLLMVFFSISIKEATMYSLAIIFFSQLSHLATIVVVTGLNQYHLAPVPVIFLASICGG
                     VLGTVVSKVLPENWVRYCFKGMLFFVMGMTLYNLFHIL"
     gene            complement(1470..2318)
                     /locus_tag="VVR63_001787"
     CDS             complement(1470..2318)
                     /locus_tag="VVR63_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formylglycine-generating enzyme family protein"
                     /protein_id="HEU6129774.1"
                     /translation="MKMKKIKGGTFMMGTNSEEGFLDDFEGPQVAVSVKDFSIADTPV
                     TNQEFAQFVKETGYKTLAERQEWSFVFILFVPEAEREGYPHPAGAPWWLQVSNACWKH
                     PYGENSNLVGLEDHPVVHVALEDALAFCNWSGMSLPTEAQWEYAARGGRQSEYPWGDT
                     LLEGGYYHANTWQGRFPYENTALDGFIGTAPVYEFLPNDFGLYQMIGNVWEWCRNPRY
                     TLLASFNEDDYELPKYGIQDEEYAIRGGSFLCHCSYCNRYRVAARNGCISTSTSSHLG
                     FRCLKE"
     gene            complement(2315..3790)
                     /locus_tag="VVR63_001788"
     CDS             complement(2315..3790)
                     /locus_tag="VVR63_001788"
                     /EC_number="3.1.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arylsulfatase"
                     /protein_id="HEU6129775.1"
                     /translation="MVQTKQPNIILIVVDQMRADALSLNSKDKLVSTPTLDMMASVGY
                     NFENAYSPVPSCVPARAALLTGLDQDKSGRVGYQDEVPWNFTNTLPKVFKDMGYQTEC
                     IGKMHVFPSRQRLGFDHVLLHDGYLHVDRKYDKAYGSQFDYASDYLAFLKGKVGYDVD
                     LIDDGMDCNSWEARPWDKDEKLHPTNWVVSESISFLQRRDPTVPFFLKMSFEKPHAPL
                     NPPKYYFDIYMERLPQFLDLHIGNWEVLEKQIPSIYALRGKLKEDDQRRMVAAYFGLI
                     THIDHQISRFLTALKEFRHDKDTIIWFVSDHGDQLGEHYLFRKGYPYQGSIHIPSFIY
                     DPAGLIAGNRGTIKQLVKIQDIFPSLVDLAGGTTTDELDGRSVKNLLFGQYEGWRTEF
                     HGEHALGKDSSQYILTDQWKFIWFPVLNHYQLFDMKKDPHEMNDLYPSEKYQPIVRQM
                     KKKLVDFLRYREEGFVVDEELVPVELSKITPTLTKTGDSQS"
     gene            complement(4113..5468)
                     /locus_tag="VVR63_001789"
     CDS             complement(4113..5468)
                     /locus_tag="VVR63_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEU6129776.1"
                     /translation="MNTMLDKMQEKLSPIAMKVGNQKFLVALRDSFVGTMPVIMTGSI
                     ALLLNAFLVDLPQQFHLESITKTFQWLVDINNLVFKGSIPIVSLLFIYCLGVNIAKIY
                     KVDTVSAGLVSLASFVISIGSTVTKSFPLANVGDVKLDQILQGIDNLAFDGKNLMVTI
                     GNVIPGNHINARGYFTAMMIGFLASIIFCKVMKKNWVIKLPDSVPPAIAKPFTSIIPG
                     FMAMYIVAILTYVFHLLSNDLLIDWVYKVLQTPLLGLSQSFFAVILMIFLNKLFWFFG
                     LHGGNVLAPIMEGLFGVAMLANLDAFQKGEPIPYIWTSGSFGAFVWFGGLGLVLAILI
                     FSRNSHYRKVAKLGLAPVLFNIGEPVNYGLPVVLNPLLFIPFVLSPVFMATVAYWATS
                     WGLVSPVTQNVTWVMPPILYGFFSTAFDWRAIILSVVCLIISVLTYFPFVKMADKTEL
                     S"
     gene            complement(5478..5795)
                     /locus_tag="VVR63_001790"
     CDS             complement(5478..5795)
                     /locus_tag="VVR63_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEU6129777.1"
                     /translation="MNESNLESAMGLIMYGGEAKSNAMEAIQAAKKGDFSKANRRLAD
                     ANAALLQAHKAQTEMLTREAQGEETSISLLMVHAQDHLMTSLTFVDLAKEVVEVYERF
                     EKN"
     gene            complement(5812..6129)
                     /locus_tag="VVR63_001791"
     CDS             complement(5812..6129)
                     /locus_tag="VVR63_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001151647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU6129778.1"
                     /translation="MAKVTIMLACAAGMSTSLLVTKMQKAAEDKGLDAEIFAVPAPEA
                     EEIVATKEVNVLLLGPQVRYLLGDFQEKLKDRQIPVAVIPMTDYGMMNGSKVLDLAES
                     LLD"
     gene            complement(6144..7040)
                     /locus_tag="VVR63_001792"
     CDS             complement(6144..7040)
                     /locus_tag="VVR63_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HEU6129779.1"
                     /translation="MKRLISANPSEILQMNAEELKQSILASEGRVVLSENVVTRETFV
                     GDITNSEIARAFGADMILLNCVDVFEPKIYALDSSGDDVIHRLHQLVACPIGVNLEPI
                     DPSAKMLEETQEIVAGRVASVETLKRIEELGFDFVCLTGNPGTGVSNREIIKAVQTAK
                     ENFSGLIIAGKMHGAGVNEPVAELSVAEQLLEAGADVILVPAVGTVPAFHDQELREVV
                     DLVHSKGGLVLSAIGTSQETSDTDTIKEIALRNKICGVDIQHIGDAGYGGLATVDNIY
                     ALSKAIRGVRHTVSRLARSVNR"
     gene            complement(7043..8305)
                     /locus_tag="VVR63_001793"
     CDS             complement(7043..8305)
                     /locus_tag="VVR63_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEU6129780.1"
                     /translation="MEKLLQEKLLPVAARLGNNKALVSIRDGITLTIPLLLIGSLLMV
                     IASFPIPGWEKYLGDIGVADYLWKGVDSSFGLLGLVASFGIAYFMARQYKVDGIPAGI
                     VSLSSFITVTPFIRGEAGAGMPTAFMASKGLFVAMILGLINGYIYQWFINHNIQIKMP
                     DGVPPAVSKSFSAIIPGAVTIVGWLIVYATLDKLSLPNLHEIAQVALGGPLGLLGNNV
                     IGLLILIFLNSSFWFVGLHGGNVVNAVMKPLWLANLDANKVAYQTGETLPNIFTSVFM
                     DNFVFIGGGGATIGLVLALGYLAHKKKASKQLKTLAPITVIPGLFNINEPAMFGVPIV
                     LNILLLVPFILAPMFNLLVAWGAMASGLVPLTYTDPGWTMPPVISGLLATGSISGSLL
                     QIVLIVLDVLLYLPFVIAIEKRFKLLED"
     gene            8585..9763
                     /locus_tag="VVR63_001794"
     CDS             8585..9763
                     /locus_tag="VVR63_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HEU6129781.1"
                     /translation="MTLSKKQLQLRAKILETVYTLGPISRIEIATKTGITPATTSSIT
                     NDLIKENILLELGEDEHDTSVGRKKILLDIQAKRFYYIGCELSEKHFTFALGDNLGNI
                     LKEEKEIVTKQLIQEKGNQLINQTLKQFLNNCSDYEIEAIGIALPGRYLDDYKITTNN
                     PLWQHIDLEMIQSHFDKPLFFSNNVNCMAIGKRLFSRQQNDPNFAYFHFARGMHCSYI
                     YDGNIYGKGNLMIGEIGHTVVSSEGEECSCGRKGCLQTFAGESWLIKKSKILYHQSPY
                     SLLPSLVKNADDIDIQVILTAYQLGDTGIITLIHQALLYLSQTILNISMMIDSQKIYL
                     HSPLLTNQHIIQKLYSEMNYKPKLLYNRLPEVIIEPYNDFTAAHSAIALCLYHTILHS
                     "
BASE COUNT         3435 a         2076 c         1418 g         2955 t
ORIGIN      
        1 agtttctata gtaaaatgaa ccaaaaatag tacacgttgc ggtataatgt tcttgtggca
       61 tattcattag attttcgtaa aaagttctct cctatttgtg agcgaacagg tatagtcaat
      121 tgattgtcag tttgaagacc aagagtcgta aggcaaagga tatggcagaa tccatccaag
      181 ggtggctggc acaatttcta gtgaacctct ttaaatctat tacgtttgac tgtggaaaag
      241 agttttcaaa atggaaagat atttccaatc atcacgatag tgagagcttt tttgcgaatc
      301 taggatgtcc aagacagcgg tgtctcaacg aacattcaaa tagactttta aggtgtcatg
      361 acttgccaaa gcagacagat ttcaacgaag tcagtcaaga attttaggct gggtaaaaac
      421 tcaatttcag gagaaaatga aataaatatt cccacaataa aacgcatagt atcaaagttt
      481 ttccaacacc tgatattata cattttttaa ttttaaagac tttttcccag cctcaagaaa
      541 tcacatccca cctaaatcct ttggatacca aatacctcat caggtatttt ctgagttggt
      601 aagactgtct agcttaattt gacaaatgga gggcgttaaa tccagttttt acaggaagtc
      661 tatttaaata ttttcacact gaccttacaa aatatgaaat aaattatata aagtcattcc
      721 catgacaaag aataacatcc ctttaaaaca gtatcttacc caattttcag gtaagacttt
      781 tgatacaacc gtccccaata cccctccgca tatagaagca agaaaaataa ctggaacagg
      841 tgctaaatga tactgattta aacctgtaac cacaacaatt gtagccaaat gagacaactg
      901 ggaaaagaaa ataattgcaa gagaatacat cgttgcttct tttatcgaaa tagaaaaaaa
      961 caccatcaat aaagatacat tgagcggacc tccaccaatc cctaaaaaac tagaaatcaa
     1021 gcccaataga agaccacaaa tcatatagaa tcctatctta tcaaattgat aagttttttt
     1081 aaaatctgtt aaaacaaatg atacaagtag catcacaaat agtaaaatca tttgaacaat
     1141 ggatactagc cgtactgata attgagataa caaaacttga aaaataagat gacctagaaa
     1201 ccctcctaaa acagaagaaa aggataccgt aaaaatcaat ctccatttta tctctttact
     1261 ttgtgaaaat cttttggttg ttgaaataat cgccattata aaaacagaga aactagaata
     1321 aaaagcaata tcactgaccg aatggtatcc aaaactatcc ataagtggct taattataat
     1381 tccaccaccc atgcctgata tagaacccaa tccactagct attataatga ttagaaaata
     1441 aataatctca accacttttt aagtccatcc tattctttca aacatctaaa acctagatgg
     1501 ctactagtgg aagtagaaat acatccattt ctagcagcta ctcggtatcg attacaataa
     1561 gaacaatgac ataaaaagga acctcctctg atagcatact cctcatcttg tatcccatat
     1621 tttggtaact catagtcatc ttcattaaaa ctagctaata aggtatatct cggattgcga
     1681 caccattccc aaacattccc aatcatttga tatagaccaa aatcattagg taaaaattca
     1741 tagacaggag ccgttcctat aaatccatct aaggcagtat tttcataagg aaatcttcct
     1801 tgccaagtat tggcatgata atatccacct tctaaaagag tatctcccca aggatattca
     1861 gattgtcttc ctcctctagc agcatattcc cactgtgctt cagtcggtaa agacattccg
     1921 ctccaattac agaaagccaa tgcatcttct aaagcaacat gaactactgg atggtcttct
     1981 aaacccacta gattactgtt ctcaccgtag ggatgtttcc agcaagcgtt cgaaacttgt
     2041 aaccaccacg gagccccagc aggatgagga tatccctccc tttctgcctc cggaacgaac
     2101 aatataaaaa caaaagacca ctcttgtcgc tcagctagtg ttttatagcc tgtttctttc
     2161 acaaattgag caaattcttg attcgtaact ggagtatccg caatggaaaa atcctttaca
     2221 ctaacagcga cttgaggacc ttcaaaatca tctaaaaagc cctcttcaga atttgttccc
     2281 atcataaatg tcccaccctt gatttttttc attttcatga ttgactatcc cccgttttcg
     2341 ttagagttgg cgttatttta gaaagttcaa caggaactaa ctcttcatcc acaacaaaac
     2401 cttcttctct atatctaaga aagtctacta attttttctt catctgacga acaataggtt
     2461 gatatttttc acttggatac aaatcattca tttcatgcgg atcttttttc atatcaaata
     2521 actgataatg atttaaaaca ggaaaccaga taaatttcca ctggtctgtc aaaatatatt
     2581 gactagaatc ttttcctaaa gcatgttcac catgaaattc tgttcgccac ccctcgtact
     2641 gtccaaataa taaattctta acactccgtc catctagttc atctgtagta gttcctcctg
     2701 ccaaatccac gagtgaagga aaaatatctt gaattttcac taattgcttg attgttcccc
     2761 tattaccagc tatcaatcca gccggatcgt aaataaacga aggaatgtgg atacttccct
     2821 gataaggata tccctttcta aacagataat gttcaccaag ctgatctcca tgatccgaaa
     2881 caaaccagat aatcgtatct ttatcatgac gaaattcttt tagggcagtc aaaaagcgac
     2941 taatttgatg gtctatatga gtaatcaatc caaaataagc agcaaccatt cttctttgat
     3001 catcttcctt taatttccct cttaaagcat aaatagacgg aatttgcttt tctaatactt
     3061 cccaattccc gatatgcaaa tcgagaaatt gaggcaagcg ttccatatat atatcaaaat
     3121 agtattttgg gggatttaat ggagcatgtg gtttttcaaa agacattttg agaaaaaaag
     3181 gaaccgttgg atctcttctt tgtaaaaatg aaatggactc actcacaacc cagtttgttg
     3241 gatgtaactt ctcatcttta tcccaaggtc tagcttccca agaattacaa tccattccgt
     3301 catcaatcaa atcaacatca taaccaactt taccctttaa aaaggctaga tagtcactag
     3361 cataatcaaa ttgacttcca taagccttat catactttct atcaacatgt agatacccat
     3421 cgtgaagtaa gacatgatca aacccaagtc tctgtctgga aggaaaaaca tgcatcttac
     3481 caatacactc tgtttgataa cccatatctt taaagacttt tggaagagta ttagtaaaat
     3541 tccaaggcac ctcatcttga taaccaactc gtccactttt atcttggtct aagccagtca
     3601 ataaagctgc cctagcagga acgcaagaag gaactggaga ataggcattt tcaaaattat
     3661 aacctacact agccatcata tctaatgttg gagtgctaac tagcttatcc ttactattca
     3721 aggataaggc gtctgctctc atttgatcta caacaatcaa aataatattt ggctgttttg
     3781 tctgaaccat aaaatctcct ttctaatatg gcaaaagagg cacaagaaga tatctacctt
     3841 tactgcaccc ctttctatat caatctctct atataaaaca ataacattct tgttatgttt
     3901 tatagaaaaa tgaactaaaa tatgactaaa tcgattagga aattcaaatc attttctagt
     3961 actgttttag aagttacagt gtactattcc aacttcaata aactataaac ctttgtctaa
     4021 taacaatttt agtggagata agaaatccta cacctaactc atcttacacg taatctattt
     4081 ctattttatc acaaaaaacg caagtaagac cattaactca attcagtttt atctgccatt
     4141 ttcacaaatg ggaaataagt caagacacta ataatcaaac aaacaactga taagatgatg
     4201 gcacgccaat caaatgctgt agagaagaaa ccatataaaa ttggaggcat tacccaagta
     4261 acattttgtg taacaggtga aacaagaccc cagcttgttg cccagtaagc taccgttgcc
     4321 atgaaaaccg ggctaagtac aaatggtata aatagcaaag gattcaagac aactggtaaa
     4381 ccataattta ccggctcacc aatattaaac agaactggtg ctagaccaag tttagcaact
     4441 tttcgataat gactgtttct tgaaaaaatt aaaatagcaa gtactaatcc taatcctcca
     4501 aaccagacaa acgccccaaa agacccactt gtccatatat aaggaatcgg ttcacctttt
     4561 tggaaagcat ccagattcgc taacatagca actccaaata gcccttccat gatgggagcc
     4621 aatacatttc ctccatggag accaaaaaac cagaataact tattcaaaaa gatcatcaga
     4681 ataactgcaa agaaactttg agacaaacct agtaatggcg tttgtaacac cttgtaaacc
     4741 caatcaatca ataagtcatt gctaagtaaa tggaaaacat aagtcaagat ggctactata
     4801 tacatcgcca taaatcctgg aatgatagaa gtgaacggct tagcaatcgc agggggaact
     4861 gaatctggta acttgattac ccagttcttt ttcattactt tacagaaaat aatagaggct
     4921 aaaaatccaa tcatcatggc tgtaaagtag cctctggcat taatatggtt tcctggaatc
     4981 acattcccaa tagttaccat cagattttta ccatcaaatg ctagattatc aattccttgt
     5041 aagatctgat ctaatttcac atctcctaca tttgccaaag ggaaactctt tgtaactgta
     5101 cttccaatcg aaatgacaaa cgaagcaagt gataccaaac cagcagaaac tgtatcaacc
     5161 ttgtaaatct tagcgatatt cactcccaag caatagatga acaacaagga aacaattggt
     5221 atacttccct tgaataccaa attattgatg tcaacaagcc actgaaaggt tttcgtaata
     5281 ctttctaggt gaaattgttg tggtaaatcc actagaaaag catttaataa caaagcaatg
     5341 gaacctgtca taataacagg catagtcccc acaaatgaat cacgtaaagc aactaaaaac
     5401 ttctgattcc caactttcat tgcaattgga gaaagttttt cttgcatttt atccaacatt
     5461 gtattcatac taaactccta atttttttca aatcgttcgt atacttctac cacttctttc
     5521 gccaagtcaa caaaagtcag actcgtcatt aaatgatctt gcgcgtgtac catcaagagg
     5581 ctaattgatg tttcttcccc ctgtgcctct cttgtcaaca tttctgtttg agccttatgc
     5641 gcctgtaata aggcagcatt cgcatcagct aatcttcgat tggctttaga gaaatcccct
     5701 ttttttgctg cctgaatagc ctccatagca ttacttttgg cttccccacc atacataatt
     5761 agccccattg cagattctaa attactttca ttcatagcat tctcctcaat cttagtctaa
     5821 taaactttca gctaaatcta agactttaga accattcatc attccataat ctgtcatcgg
     5881 aataaccgcc acaggaatct gtctatcttt tagtttttct tgaaagtccc ctagtaaata
     5941 gcgaacttga gggcctaaaa gcaacacatt tacttccttt gttgctacaa tttcttctgc
     6001 ttcaggagct ggaactgcaa aaatttctgc atccaacccc ttatcttctg ctgccttttg
     6061 catctttgtc actagcagac ttgtactcat acctgctgca catgctaaca taattgttac
     6121 tttagccata gcttactcct ttatcaccta tttactgacc tagccaagcg agatactgta
     6181 tgtctcactc ctctaattgc cttgctcaat gcataaatat tatcgactgt tgccagtccc
     6241 ccatatcctg cgtcacctat atgttgaata tcaactccac aaattttatt tctaagtgca
     6301 atttccttga tagtatctgt atcagatgtt tcttggctag taccaatagc actcagtact
     6361 agcccaccct tactatgaac gagatcaacg acttcacgca actcttggtc atgaaaggct
     6421 ggaacggttc caactgctgg aacaagtatc acatccgcac ctgcttccaa caattgctct
     6481 gctacagaaa gctctgccac aggctcattc actcctgccc cgtgcatctt acctgcaata
     6541 atcaaaccag aaaagttttc cttagcagtt tgaacagcct taatgatttc tcgattgcta
     6601 actcctgttc caggatttcc agtcaaacag acaaagtcaa aacctaactc ctctattcgc
     6661 ttcaatgttt caacactagc aacacgacct gcaacaattt cctgtgtttc ctctagcatc
     6721 tttgcagatg ggtcaatcgg ttccaaattt acaccaattg gacaagcaac aagctggtgt
     6781 aagcgatgaa taacatcatc acctgaacta tccaaagcat aaattttagg ctcaaaaaca
     6841 tcaacacaat tcaataaaat catatcagct ccaaaagctc tagcaatttc agaattagtt
     6901 atatccccaa caaatgtctc acgagtaact acattttcag atagaacaac tctaccttca
     6961 cttgctaaaa tactttgttt taattcttca gcattcatct gtaatatctc agatggattt
     7021 gcactaatta aacgtttcat tctcaatcct ccaataactt aaaccgtttt tcaatagcta
     7081 ttacaaatgg taaataaagt aagacatcca aaacaatcaa tacaatttgt aataatgaac
     7141 cagaaatact tcctgtagca agtaaaccac ttataacagg tggcatagtc caacctggat
     7201 ctgtataagt tagcggaacc aaacctgatg ccattgctcc ccacgctact agtaagttaa
     7261 acattggagc taagataaat ggaactagta acaaaatgtt caaaacaata ggaacgccaa
     7321 acattgctgg ttcatttata ttaaataatc caggtataac agttataggt gccaaagttt
     7381 ttagttgttt actagctttc ttcttatgtg ctaaatatcc taacgcaaga actaaaccta
     7441 tggttgcacc accgccacct atgaatacaa aattatccat aaatacgcta gtaaaaatat
     7501 ttggaagagt ttctccagtt tgataagcta ctttatttgc atctagatta gctaaccata
     7561 acggtttcat aactgcatta acaacatttc ctccgtgtaa tcctacaaac caaaaactac
     7621 tattaaggaa aattaagata agaagaccaa taacattatt tcctaaaagt ccaagtggac
     7681 ctcccaaagc tacttgagca atttcatgaa gattaggtaa acttaattta tctaaagttg
     7741 cataaacaat caaccaacca acaatagtca ctgcaccagg aataatggca ctaaagcttt
     7801 tagatactgc tggtggaaca ccatccggca tttttatctg tatattatga tttataaacc
     7861 attggtagat atagccatta atcaatccta aaatcatagc aacaaataaa ccttttgatg
     7921 ccatgaaagc ggtaggcatt cctgctccag cctctcctct aatgaaaggc gtaactgtaa
     7981 taaaagatga taatgacaca ataccagcag gaataccatc aactttgtat tgtctagcca
     8041 taaagtaagc gataccaaaa ctagctacaa gaccaagtaa tccaaaacta ctatcaacac
     8101 ccttccataa atagtcagca acaccaatat cacccagata tttttcccat cctggaatag
     8161 gaaaacttgc aataaccatt agtaatgaac ctatcaacaa taaaggtata gttagagtaa
     8221 taccgtctcg aatagaaacc aacgctttat tattacccaa tctagccgct actggaagta
     8281 acttttcttg taataatttt tccataacct tttcctctta aatatatttt attatcaaaa
     8341 gttatcaatt atctttattt tttgacgtca agttgttatt tgattatctt ttgttattta
     8401 tattttacaa ctataagaaa gccttgtcaa ggatttgtgt aaacatttga ttatttttta
     8461 ttatcaatat ataataaaaa gagaccagta agtaatgaaa agcttaaaaa gattaacatc
     8521 tacatttatc catagcaaaa aatcatagga ttttaagaat ctgacaacta ggaagaaaac
     8581 taatatgacc ttatctaaga aacaattaca actaagagct aaaatactgg aaacagttta
     8641 cacattaggt cccatttcac gaattgaaat cgctactaaa acaggaataa cacctgcaac
     8701 aactagcagt atcacaaatg atctgattaa agaaaatatt ctcttagaac ttggtgaaga
     8761 cgaacacgat acaagcgtag ggagaaaaaa aatcctgcta gacattcaag ctaaacgatt
     8821 ttactacatt ggttgtgaac tatctgaaaa acatttcact tttgctttag gagataatct
     8881 aggaaatatc ttaaaggaag agaaagaaat tgttactaaa cagttaatcc aagaaaaggg
     8941 aaatcaactc attaaccaga cactaaagca attcttaaat aactgctctg attatgaaat
     9001 agaagcaatt ggaatcgcgc tacctggtcg ctatttagat gattataaaa taacaacaaa
     9061 caatccttta tggcaacata tcgacttaga aatgattcaa tcccactttg ataagccttt
     9121 gtttttctct aacaatgtta actgtatggc tataggtaaa cgcctattta gtcgccaaca
     9181 gaatgaccct aattttgctt attttcattt tgctagaggt atgcactgtt cttatatcta
     9241 cgacggaaac atttatggga aaggaaatct aatgattgga gaaatagggc atacagttgt
     9301 ttcatctgag ggagaagaat gtagttgcgg gcgcaaggga tgcttacaaa cttttgctgg
     9361 agaatcttgg ttaatcaaaa aatcaaaaat tctatatcat caatctccct attctctact
     9421 tcctagttta gtcaaaaatg ccgatgatat tgatatccaa gttattttaa ccgcttatca
     9481 attaggtgac actggaataa tcacacttat ccatcaagcc ttactctatc ttagtcaaac
     9541 cattttaaat atcagtatga tgattgactc tcaaaaaatc tacctacata gtcctttact
     9601 aacaaatcaa cacatcatcc aaaaactata tagtgaaatg aactacaaac ccaaactgct
     9661 ctataatcgc ctacctgaag tcattattga accttacaat gattttacag ccgcacactc
     9721 agctattgca ctttgtttgt atcatacaat tctacattct taattttcta ttacatttaa
     9781 taaataggct aaaaagaggg agtatatcat aaaaagcgaa taaacctgtt ttctgaaaat
     9841 cagaattctg ttttgttcgc tttctttata tttggaatta tact
//
LOCUS       DAVHTH010000065         9736 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.065, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000065 DAVHTH010000000
VERSION     DAVHTH010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9736)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9736)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9736
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.065"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            complement(<1..420)
                     /locus_tag="VVR63_001795"
     CDS             complement(<1..420)
                     /locus_tag="VVR63_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComEC family DNA internalization-related
                     competence protein"
                     /protein_id="HEU6129782.1"
                     /translation="MLQWIKNFSIPLIYLSFLLLWLYYAIFSASYLALLGFVFLLVCL
                     FIQFPWKSAGKVLIICGIFGFWFVFQNWQQSQASQNLADSVERVRILPDTIKVNGDSL
                     SFRGKSNGRAFQVYYKLQSEEEKEAFQALTDLHEIGLE"
     gene            complement(404..1054)
                     /locus_tag="VVR63_001796"
     CDS             complement(404..1054)
                     /locus_tag="VVR63_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComEA family DNA-binding protein"
                     /protein_id="HEU6129783.1"
                     /translation="MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQ
                     AEVAAVSKDLVSEEEVNKEEKEEPLEQDLITVDVKGAVKSPGIYDLPVGSRVNDAVQK
                     AGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGLGTASSISKEKKVNLNKA
                     SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGGKTIEKLKDYVTVD"
     gene            complement(1122..1691)
                     /locus_tag="VVR63_001797"
     CDS             complement(1122..1691)
                     /locus_tag="VVR63_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6129784.1"
                     /translation="MESIFVKLAQYPSIETERLLLRPVTLDDAEAMFDYASDKGNTRY
                     TFPTNQSLEETKNNIAQFYLANPLGRWGIELKDNGKFIGTIDLHKIDPVLKKAAIGYI
                     INKKYWNQGLTTEANRAVIELAFEKIGMNKLTALHDKDNPASGKVMEKSGMRFSHAEP
                     YACMDQHEKGRIVTRVHYVLTKEDYFANK"
     gene            1868..2293
                     /locus_tag="VVR63_001798"
     CDS             1868..2293
                     /locus_tag="VVR63_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine dehydrogenase"
                     /protein_id="HEU6129785.1"
                     /translation="MLIGIPKEIKNNENRVALTPAGVHSLVSRGHRVLIETNAGLGSG
                     FTDADYQKQGAEIVATAGEAWAAELVVKVKEPLNSEYGYLRDDLLLFTYLHMAAAPEL
                     ADAMLAAKTTGIAYETVRDNQGQLPLLVPMSEVAGRMAV"
     gene            2380..2706
                     /locus_tag="VVR63_001799"
     CDS             2380..2706
                     /locus_tag="VVR63_001799"
                     /inference="COORDINATES: protein motif:HMM:NF013430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine dehydrogenase"
                     /protein_id="HEU6129786.1"
                     /translation="MIGDGVVGTHAARIALGLGAQVTILDISAKRLSVLEEVFGSQIQ
                     TLISNSFNIEASVRDADVVIGAILIPGAKAPELVTDEMVKQMRPGSVSLTLLLTKVAL
                     SKQLTV"
     gene            2652..2978
                     /locus_tag="VVR63_001800"
     CDS             2652..2978
                     /locus_tag="VVR63_001800"
                     /inference="COORDINATES: protein motif:HMM:NF013430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6129787.1"
                     /translation="MVDVAVDQGGVIETADRVTTHDEPVYEKHGVLHYAVANIPGAVA
                     RTSTIALTNVTLPYIEALAGKGFAQAISEDEGLRQGVTTYQGYLTSLPVAQGLNRDYT
                     DINDLV"
     gene            complement(3345..3605)
                     /locus_tag="VVR63_001801"
                     /pseudo
     CDS             complement(3345..3605)
                     /locus_tag="VVR63_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003069408.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TfoX/Sxy family protein"
     gene            complement(3608..4109)
                     /locus_tag="VVR63_001802"
                     /pseudo
     CDS             complement(3608..4109)
                     /locus_tag="VVR63_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566985.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            4145..4324
                     /locus_tag="VVR63_001803"
     CDS             4145..4324
                     /locus_tag="VVR63_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6129788.1"
                     /translation="MTQEDALIVISHIKVLSIVPNRCLKPLDKTFSLYNWIFLSQKYI
                     LLQANFLKISRVQLQ"
     gene            complement(4302..5270)
                     /locus_tag="VVR63_001804"
     CDS             complement(4302..5270)
                     /locus_tag="VVR63_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HEU6129789.1"
                     /translation="MKEHSIDIQLSHPDDLFHLFGSNERHLRLMEEELDVVIHARTEI
                     VQVLGEESACEEARQVIQALMVLVNRGMTVGTPDVVTAISMVKNDEIDKFVALYEEEI
                     IKDNTGKPIRVKTLGQKLYVDSVKQHDVTFGIGPAGTGKTFLAVTLAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKDQTTRLMEREIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFHSKMIVNGDISQIDLPRNVKSG
                     LIDAQEKLKNIHQIDFVHFSAKDVVRHPVVAQIIRAYEYSTEVAHD"
     gene            complement(5356..5571)
                     /locus_tag="VVR63_001805"
     CDS             complement(5356..5571)
                     /locus_tag="VVR63_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HEU6129790.1"
                     /translation="MRKSFYTWLMTERNPKSNSPKAILADLAFEESAFPKHTDDFDEV
                     SRFLEEHASFSFNLGDFDSIWQEYLEH"
     gene            complement(5580..6434)
                     /gene="cvfB"
                     /locus_tag="VVR63_001806"
     CDS             complement(5580..6434)
                     /gene="cvfB"
                     /locus_tag="VVR63_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HEU6129791.1"
                     /translation="MNTNLASFIVGLIIDENDRFYFVQKDGQTYALAKEEGQHTVGDT
                     VKGFAYTDMKQKLRLTTLEVTATQDQFGWGRVTEVRKDLGVFVDTGLPDKEIVVSLDI
                     LPVLKELWPKKGDQLYIRLEVDKKDRIWGLLAYQEDFQRLARPAYNNMQNQNWPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYAEPRLGQVLDARVIGFREVDRTLNLSLKPRSF
                     EMLENDAQMILTYLESNGGFMTLNDKSSPDDIKATFGISKGQFKKALGGLMKAGKIKQ
                     DQFGTELI"
     gene            complement(6494..7051)
                     /gene="frr"
                     /locus_tag="VVR63_001807"
     CDS             complement(6494..7051)
                     /gene="frr"
                     /locus_tag="VVR63_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HEU6129792.1"
                     /translation="MANVIIEKAKERMTQSHQSLAREFGGIRAGRANASLLDRVHVEY
                     YGVETPLNQIASITIPEARVLLVTPFDKSSLKDIERALNASDLGITPANDGSVIRLVI
                     PALTEETRRDLAKEVKKVGENAKVAVRNIRRDAMDEAKKQEKAKEITEDELKTLEKDI
                     QKVTDDAVKHIDDMTANKEKELLEV"
     gene            complement(7060..7797)
                     /locus_tag="VVR63_001808"
     CDS             complement(7060..7797)
                     /locus_tag="VVR63_001808"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HEU6129793.1"
                     /translation="MANPKYKRILIKLSGEALAGERGVGIDIQTVQTIAKEIQEVHSL
                     GIEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQQVGVDTRVQ
                     TAIAMQQVAEPYVRGRALRHLEKGRIVIFGAGIGSPYFSTDTTAALRAAEIEADAILM
                     AKNGVDGVYNADPKKDKTAVKFEELTHRDVINKGLRIMDSTASTLSMDNDIDLVVFNM
                     NQSGNIKRVVFGENIGTTVSNNIEEKE"
     gene            complement(7881..9215)
                     /gene="trmFO"
                     /locus_tag="VVR63_001809"
     CDS             complement(7881..9215)
                     /gene="trmFO"
                     /locus_tag="VVR63_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HEU6129794.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAERGIPVKLYEMRGVKSTPQHK
                     TDNFAELVCSNSLRGDALTNAVGLLKEEMRRLGSVILESAEATRVPAGGALAVDRDGF
                     SQMVTEKVVNHPLIEVVRDEITELPTDVITVVATGPLTSDALAEKIHALNNGDGFYFY
                     DAAAPIIDVNTIDMSKVYLKSRYDKGEAAYLNAPMTKQEFMDFHEALVNAEEAPLNSF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLEQT
                     YRSKKQPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKEESEVIFPETTAIGSLAH
                     YITHADSKHFQPMNVNFGIIKELEGERIRDKKARYEKIAERALADLEEFLTV"
     gene            complement(9510..9704)
                     /locus_tag="VVR63_001810"
     CDS             complement(9510..9704)
                     /locus_tag="VVR63_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEU6129795.1"
                     /translation="MEAEAIRRNCERGAIFSGKIKHHEDSQFKGDHYVECYAVLDNTV
                     IARDRITVPIDPLCGKDFIE"
BASE COUNT         2731 a         2248 c         1864 g         2893 t
ORIGIN      
        1 ttctagtcct atctcatgca ggtcggttaa agcttgaaag gcttctttct cctcctcgga
       61 ctggagttta taatagactt ggaaagcacg accgttagac ttgccacgaa aggatagact
      121 atcaccatta accttaatag tatcaggtaa aatccgtacc ctttcaacag aatccgccag
      181 attttgactc gcttgactct gttgccaatt ttgaaaaaca aaccaaaatc caaagattcc
      241 gcaaattatt agaactttac cagcagattt ccacggaaat tggataaaga gacagactag
      301 cagaaaaaca aagcccaaca aagcaagata agatgctgag aaaatagcgt aataaagcca
      361 aagtaataga aaactcaggt aaattagggg aatagagaaa ttcttaatcc actgtaacat
      421 agtctttaag cttttctatt gttttgccac caatgccaga gaccttcttg agctcgtcta
      481 ctgacttgaa cttgccattt gcctcacgat ggtcgataat gtcctgagct cgttttcctc
      541 ccagtccctt gacctgcttg agttcttcca gactggcctt gttgagattg accttctttt
      601 ccttgcttat tgaagaagct gtccccaaac cagtctgttg gctaactgct tcttctccct
      661 tagtaggaac gtaaaccaga gcctcatcac taactttctg agctagattg agcgacttgc
      721 tgtctgcttg ctctgtcaag ccaccagcct tctgaacagc atcattgact cgactaccta
      781 caggcaagtc ataaatccct ggcgatttga cagcaccttt gacatctact gtgattagat
      841 cttgttcaag gggttcttcc ttttcttcct tgttcacttc ctcttcggat accaaatcct
      901 tggaaacagc tgcgacttca gcctgcaaat tcgtctcttt gacaggtgtt tgtggagctg
      961 gttttagcag gaaaaatcct cctacaagca agcccagacc agtacagatg acgatgattt
     1021 tatactcttt gattttctcg ataattgctt ccatattttc tcctctctta gattattcgt
     1081 aagaggaaga aaaaacagtc gaaaaatttc ttttcaactg cttatttatt tgcaaaatag
     1141 tcttccttgg tcaagacata atgaactctt gtcacgattc ggcctttttc atgctggtcc
     1201 atacaagcat atggttctgc atgggaaaaa cgcatgcctg atttctccat gacctttcct
     1261 gacgcaggat tgtccttatc gtgaagggca gtcaacttat tcatccctat cttctcaaaa
     1321 gctagctcaa tcacagcacg attggcttct gtcgttaatc cttgattcca atacttttta
     1381 ttgataatgt agccaatagc tgccttctta agaacaggat caatcttgtg taagtcaata
     1441 gttccgataa acttgccgtt atcttttaat tcaatccccc aacgtcccaa gggattagcc
     1501 aagtagaact gagcaatgtt attcttggtt tcttccaaac tttgattggt tggaaaagtg
     1561 taacgtgtat tacccttgtc cgaggcatag tcaaacattg cttccgcatc atccaaagtt
     1621 acaggtctaa gcaataaacg ctccgtttct atagacggat actgggcaag ttttacaaaa
     1681 attgattcca tacttttccc tccattagag cttgattttc actagtctag cataaaaaaa
     1741 tttggatgac aagtttttct tgatttttga agcggtttca tatacaatga aaccgtcaca
     1801 tttttgattt atgaactgga atgtgacaac caaaacaaga ccgtcaattg aaaggtaggt
     1861 tatctcaatg ttaatcggaa tcccaaaaga aattaaaaat aacgaaaacc gtgtcgccct
     1921 cacacctgca ggtgttcata gcttagttag tcgtggtcat cgtgtcctta tcgaaacaaa
     1981 tgctggtctc ggttctggct ttactgatgc tgactatcaa aagcaaggag ctgagattgt
     2041 cgctactgct ggtgaagctt gggcagcaga gttggttgtg aaagtaaaag aacctttaaa
     2101 ttctgaatac ggttacttgc gcgacgatct tcttctcttc acctacttgc acatggccgc
     2161 tgctccagaa ttagcagatg ctatgttagc agcaaaaaca acaggaattg cctatgaaac
     2221 tgttcgtgac aatcaaggac aactaccgct cctcgttcct atgagtgagg ttgcaggtcg
     2281 tatggctgtt taaatcggag ctcacttcct tactaagcaa gctggtggct ctggtgttct
     2341 acctggtggt gtaccaggtg ttccaaaaga aaagtaacta tcatcggtga tggtgtcgtc
     2401 ggtacacatg ctgcccgcat cgcccttggt cttggtgctc aagtgactat tttagatatt
     2461 agtgccaagc gtctctcagt tctagaagaa gtctttggaa gtcaaattca aactcttata
     2521 tctaattcat tcaacattga agcaagtgtg agagatgctg atgtggtgat tggagccatt
     2581 ctcatccctg gtgcaaaagc accggaattg gtgacagatg agatggtcaa acaaatgcgt
     2641 ccaggctctg tatcgttgac gttgctgttg accaaggtgg cgttatcgaa acagctgacc
     2701 gtgtgacaac gcacgatgaa cccgtctatg aaaaacacgg tgttctccac tatgccgttg
     2761 ccaatatccc tggtgcggtt gcccgcactt caaccatcgc cctaaccaat gtcactcttc
     2821 cttatatcga agctttggct ggcaaaggat tcgcacaagc aatctctgaa gatgaaggct
     2881 tgcgtcaagg tgtgaccact tatcaaggtt acttgactag cctaccagtt gctcaaggac
     2941 ttaatcgtga ctacactgat atcaatgatt tagtataaat tttgaaaaga aaagggtgac
     3001 ttcgcaagtc ctacccactg tgctttgtgt catcagctat tacatcgttg gtttattgta
     3061 ctgtatactt tgcaactgga gactttcgtt ccagactcaa ttgtgcataa gaaactctaa
     3121 attgaataaa gtcaacagag tttcgcccaa ccacttcgtc ttgtaatgac aattatataa
     3181 accaaaggaa gctgagctct ttagtcccag cttcttttta tatataaaat tttacccgtg
     3241 caaagacagg gccttagcag acttcttttt tacttcgttc acccttgctt tttcttttta
     3301 ggtttgggcg ttggcagttg gttatacata gctaaaatca ggtcttatag aaacatctta
     3361 ttatcaagtt cttccactca aatcatttct ttggcacctt tgtatggaaa ctcaaaagaa
     3421 gattggtcaa tcttatctaa gactgcttgc acgggtttaa ctaaaaagcg atcatcataa
     3481 atgccgccaa taatcttgcc gcggaagtaa agaatatact cccccatcat ggaacggtaa
     3541 gtcacatcat ctaatcctga taattgttcc aaaacaaatt ccaaatagtt cttacttgat
     3601 gccatttcta atcttctagg ctctgttcag cgataacaac cgtatagagt tcttgcttaa
     3661 cctcgcatcc aattgattta aaaccctgct tttcccaaaa atgctgagat tgcggatttc
     3721 ccttaacata agccaaacgt gcctttcgaa agttcttagc aaaataagct agtgcttctg
     3781 tcacaatatg actaccaatc cctttcctct gataggcttg aacaaccata aacaaaccaa
     3841 taaaaacagt ctcctcatca ggatatgcat agacaaaatc cataacagcc acaaggtcag
     3901 atccattcca aaatccaaca aaaaaactta tcagccttag ctttaccttc aggtagacaa
     3961 agcatgtcct cttttacagt tgcaaaattt ggctctggtg gacaatgctg aaaatacaga
     4021 ggattacttt catataaaga taaaatactt ggaatatcct tttcagttag tatcctacaa
     4081 ctgtaatact tagatagttg gtcaatcatc ttttcaaatt cctactttct tgtgccctgt
     4141 gattatgaca caggaagatg cactgatcgt catcagccac ataaaagttc tttccatcgt
     4201 gcctaatcgt tgtctcaaac ctttggataa aacctttagc ctatacaact ggattttcct
     4261 ctctcaaaag tatattcttt tgcaggcgaa cttcctcaaa atcagtcgtg tgcaacttca
     4321 gtagaatatt cataggctcg gataatctga gcgacaactg gatggcgaac cacatccttg
     4381 gctgaaaaat gaacaaagtc aatctgatgg atgttcttga gtttctcttg agcatcaatc
     4441 aaaccggact tgacattacg tggcaggtca atctgactga tatctccatt gacaatcatc
     4501 ttagaatgaa agcctaaacg cgtcaagaac atcttcatct gcatgatggt cgtgttttgc
     4561 gcctcatcga gaatgacaaa ggcatcatcc aaggtccggc cacgcatata ggcaaggggc
     4621 gcaatttcga taatttcacg ctccatgaga cgagtcgttt ggtctttccc aagaatttga
     4681 tacaaggcat cgtaaacagg acgaaggtaa ggatccacct tctccttaag atcacccgga
     4741 agaaaaccta gactctctcc tgcttccacc gctgggcgtg tcaggataat tcgtttgact
     4801 tgcccacgtt taagggcagt cactgccaag gtcactgcaa ggaaggtctt ccctgtccct
     4861 gcaggtccga ttccaaaggt cacatcatgc tgtttgacac tgtccacata aagtttttga
     4921 cccaaggttt tgactcggat aggcttccca gtattgtctt tgatgatttc ttcttcgtaa
     4981 agggcgacaa acttgtcaat ttcatcattt ttgaccatgc taatcgcagt gactacatct
     5041 ggcgtaccaa cggtcatccc acgatttacc aagaccatca aagcctgaat aacttgacgg
     5101 gcttcctcac aggcagactc ttctcccaaa acctggacaa tctccgtacg agcatgaatc
     5161 acaacatcaa gctcttcttc catcaaacga agatggcgtt cattggaacc aaaaagatga
     5221 aacaggtcat ctggatgact cagttgaatg tctattgaat gttccttcaa ataaagaacc
     5281 tctctaatcc ttttatttct ttttattata gcagagggat ggagaaatta ctagcccaaa
     5341 cccaatgaat aaatgctagt gttctagata ttcctgccaa atgctgtcaa aatctcctag
     5401 gttaaaagag aaactggcat gctcctccaa aaagcgactg acctcatcaa aatcatctgt
     5461 atgttttgga aaggctgact cttcaaaagc gaggtctgcc aaaattgctt tgggactgtt
     5521 acttttagga ttgcgctcgg tcatgagcca agtgtaaaat gattttctca taagcctccc
     5581 taaatcaact ctgtcccaaa ctggtcttgc ttgattttac cagccttcat aagaccacct
     5641 aaagctttct tgaactgacc tttagaaatg ccaaaggttg ccttgatgtc gtctggagat
     5701 gacttgtcat ttaaggtcat gaaaccgcca ttgctttcca aataagtcaa aatcatctga
     5761 gcatcgtttt ccaacatttc aaaggagcgt ggtttgaggg agaggttcag agtgcggtcc
     5821 acttcacgga aaccaataac gcgcgcatct aatacttgcc ccaaacgtgg ctctgcgtaa
     5881 cgctcgctag gatgaataaa accaagcata ttattttctg gtaggtaaac aaaagttcct
     5941 gacagcttga gacggtaaac aatggctggc cagttttggt tctgcatgtt gttgtaggca
     6001 ggacgagcga gacgttggaa gtcttcttga taagccaaga ggccccagat acggtctttc
     6061 ttatccactt caagacggat gtagagttgg tcgcccttct taggccagag ttccttgagc
     6121 acagggagaa tatcgagtga cacaacgatt tccttgtcag gaaggcctgt atccacaaag
     6181 acacccaagt ccttacgaac ctctgtgaca cgtccccaac caaattggtc ctgagtggca
     6241 gtcacttcta aggttgtcag gcggagtttt tgcttcatat ccgtgtatgc aaaacctttg
     6301 accgtatccc ctactgtatg ttggccctct tccttagcaa gagcataggt ttgaccatcc
     6361 ttttgcacaa agtaaaaacg gtcattttca tcgatgatca gtccaacgat aaaacttgca
     6421 agatttgtat tcatatttcc ttctttcgaa taaaactcag ccagcaatgc caactgagtt
     6481 tttctgttta tttttagact tccaaaagtt ctttctcttt gttagcagtc atgtcgtcga
     6541 tgtgtttaac agcatcgtct gttacttttt gaatatcttt ttcaagagtc ttcaattcgt
     6601 cttcagtgat ttcttttgct ttttcttgct tcttagcttc gtccatagca tcgcgacgga
     6661 tattgcggac agccacttta gcattttcgc cgaccttctt cacttcttta gcaaggtcac
     6721 gacgagtttc ttctgtaaga gctgggataa ccaagcgaat cacagaaccg tcattagccg
     6781 gtgtgatacc aagatcagaa gcgttcaagg cacgttcgat gtctttcaat gaagacttgt
     6841 caaatggtgt taccaacaaa acacgcgctt ctggaatcgt aattgaagcg atttggttaa
     6901 gaggagtttc gactccatag tattctacat gtacacggtc aagcaagctt gcattggcac
     6961 gaccagcacg gataccacca aattcacgag caagtgattg gtgagactgg gtcattctct
     7021 ctttagcttt ttcaataatt acgttagcca tattctttct tattcctttt cttcgatatt
     7081 atttgaaact gttgttccga tattttcacc aaatacaaca cgtttgatgt tgcctgattg
     7141 gttcatgttg aagacaacca agtcaatgtc gttgtccatt gagagggttg aggctgttga
     7201 gtccatgata cgaagacctt tgttgataac atcacggtgg gtcaattctt caaacttaac
     7261 ggctgtcttg tccttcttag gatcggcatt gtacacacca tcgacgccat ttttagccat
     7321 gaggatggca tctgcttcga tttcagctgc acgaagggcc gctgttgtat ctgtcgagaa
     7381 gtatggtgaa ccaattccag caccaaagat aacgatacgg cctttttcaa ggtgacgaag
     7441 ggcacgtcca cggacataag gctctgccac ttgttgcata gcaatagctg tttgtacacg
     7501 cgtatcaacc ccaacttgtt gcaatgaatc tgccatcaca agagcattca taacagtccc
     7561 aagcattcca gtgtaatctg cctgaacacg gtccatacct gcttctgctg caggttctcc
     7621 acgccagaga tttcctccac caataacaag ggcaatttcg atacctaagc tatgaacttc
     7681 ttgaatctct tttgcgattg tttgaactgt ttggatatca atccctacgc cacgttcacc
     7741 ggcaagggct tcacctgata acttgattaa aatacgttta tacttgggat tcgccatttt
     7801 cactctcctt ctttcatcct acctatttta tcacaatttc taagattttt atagtatcat
     7861 gaacaattct ttcaaaaaaa ttagacagtc aaaaattcct ctaagtcggc aagggcacgc
     7921 tctgcaattt tttcataacg agccttctta tcacggatac gctcgccttc caactccttg
     7981 atgatcccaa aattgacatt cattggttgg aaatgtttgc tgtcggcatg ggtaatgtaa
     8041 tgagctaagc ttccaatcgc tgtcgtctcg gggaaaataa cctcgctttc ttccttgaag
     8101 agacgagctg cgttaattcc cgcaactaag cccgaagccg ccgactcaac atagccttcc
     8161 acccccgtca tctgaccagc aaagaagaga tttggttgtt tcttggaacg gtaagtctgc
     8221 tcaagaagat ttggtgaatc catgtaagaa ttgcgatgca tgacaccata acggacaaac
     8281 tccgcatttt caagacccgg aatcatttgg aagacacgct tttgttctcc ccatttgagg
     8341 tgggtctgga aaccaacaat attgtatagg ctaccagctg cattatcctg acgaagttgc
     8401 acaaccgcat aaggtgtttt aaattctcca tcacgaggtc ctgtgtagtc gtccggatac
     8461 tcaagaccga ctggcttcat agggccataa agcatagttt taatgccacg tttggccata
     8521 acttcgattg gcatacatcc ttcaaagtac ttttcttttt caaaagaatt gagcggtgct
     8581 tcttccgcat tgaccaaggc ttcatggaaa tccataaact cttgcttggt cattggagca
     8641 ttgagatagg ctgcttctcc cttatcataa cgagatttga gatagacctt actcatatcg
     8701 atagtgttga catcgataat aggcgctgct gcatcgtaga aatagaagcc atcgccatta
     8761 ttaagggcat gaatcttttc agccagggca tcgctagtca agggaccagt cgccacaact
     8821 gtaataacat ctgttggcaa ttctgtaatt tcatcacgca ccacttcaat caaggggtgg
     8881 ttgaccactt tttcggtcac catttgagag aaaccatcac gatccaccgc aagggctcca
     8941 ccggcaggaa cacgtgtagc ctcagcagat tccaagataa cagaacccaa gcgacgcatt
     9001 tcttccttga gaagaccaac tgcatttgtc aaagcatccc cacgcaaaga attggaacaa
     9061 accaactcag caaaattgtc tgttttatgc tggggtgtag acttgacacc acgcatttca
     9121 taaagtttaa ctggaatacc acgctctgcg atttggtaag ctgcttcaga acctgccaaa
     9181 ccagcaccga taacattgat ataagattga gacacgacac taatacctct ttgggagtgt
     9241 gaagttaaga ttcacattga aaaagccaat cagacttacg agatttcgag tttcttggct
     9301 caggctgaaa aagtccccca gactttcctc gctctcgaat ttcttggctc aagctgaaaa
     9361 agtcccccgg actttttcac tcccacaaat ctttctattt ttttcttcta ctagtataac
     9421 aaaaaaaggg aagaaggcaa acttccctgt ttagtcattt tcttgatgta aagagataga
     9481 gagtattcca gttaagaatc aattatatgc tactctataa aatcttttcc acataacgga
     9541 tcgataggga ctgttattct atctcttgct ataaccgtat tatctaaaac agcataacat
     9601 tcaacatagt ggtctccttt aaactgagaa tcttcgtgat gttttatttt acctgaaaaa
     9661 atagcaccac gctcacaatt tcttctaatc gcctcagctt caatatttct tactttccaa
     9721 tagacttcct gcgaaa
//
LOCUS       DAVHTH010000066         9089 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.066, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000066 DAVHTH010000000
VERSION     DAVHTH010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9089)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9089)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9089
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.066"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            81..2531
                     /locus_tag="VVR63_001811"
     CDS             81..2531
                     /locus_tag="VVR63_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HEU6129796.1"
                     /translation="MKTIGNRYVVVDLEATSTGSKAKIIQVGIVVIEDGEIVDHYTTD
                     VNPHEPLDAHIKELTGLTDQRLAQAPDFSQVARKIFDLVEDGIFVAHNVQFDANLLAE
                     NLFFEGYELRNPRVDTVELAQVFFPELEKYSLPILCRELGIPLKHAHTALSDAQATAE
                     LLLFLREKMTQLPKGLLERLLEMADALLYESYLVIEETYRNQSILSSPDLVQVQGLYF
                     KKTAASLELRKLSQDFSKNISLLNLEVREEQESFAKEVGLLLKDEPFSLIQAPTGIGK
                     TYGYLLPALSQSKERQIVLSVPTKILQNQIMEEEGKRLKEVFHTDIHSLKGPQNYLKL
                     DAFYHSLQENDENRLFRRFKMQVLVWLTETETGDLDEIGQLYRYQHFLADLRHDGNLS
                     SQSLFVTEDFWKRSQERAETCKLLVTNHAYLVTRLEDNPEFVSDRLLIIDEVQKILLA
                     LENLLQETYDIQSIIDLIDKALVGEENRVQQRILESIRFECLYLIEQFQSGKSRKNIL
                     DSLDNLHQYFSELEVEGFDELVRYFTAEGDYWLEVTETSQKKIQISSTKSGRTLLSSL
                     LPESCQVLGVSATLEISQRVSLADLLGYPEAKFVKIESRGKQEQEVVMVKDFPLVTET
                     SLEVYAREVAALLVEIQAFQQPILVLFTAKDMLLAVSDLLTVSHLAQYKNGDVHQLKK
                     RFEKGEQQILLGAASFWEGVDFSSHPSVIQVVPRLPFQNPQEPLTKKINQELNQEGKN
                     AFYDYQLPMAIIRLKQALGRSMRREYQRSLTLILDRRIVGKRYGKQIVASLAEEATVK
                     TISRSEVDEAIDRFFNEL"
     gene            2568..3791
                     /locus_tag="VVR63_001812"
     CDS             2568..3791
                     /locus_tag="VVR63_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEU6129797.1"
                     /translation="MKRSLDSRVDYSLLLPVFFLLVIGVVAIYIAVSHDYPNNILPIL
                     GQQVAWIALGLVIGFVVMLFNTEFLWKVTPFLYILGLGLMILPIVFYNPSLVASTGAK
                     NWVSINGITLFQPSEFMKISYILMLARVIVQFTKKHKEWRRTVPLDFLLIFWMILFTI
                     PVLVLLALQSDLGTALVFVAIFSGIVLLSGVSWKIIIPVFVTAVTGVAGFLAIFISKD
                     GRAFLHQIGMPTYQINRILAWLNPFEFAQTTTYQQAQGQIAIGSGGLFGQGFNASNLL
                     IPVRESDMIFTVIAEDFGFIGSVLVIALYLMLIYRMLKITLKSNNQFYTYISTGLIMM
                     LLFHIFENIGAVTGLLPLTGIPLPFISQGGSAIISNLIGVGLLLSMSYQTNLAEEKSG
                     KVPFKRKKVVLKQIK"
     gene            3802..4356
                     /locus_tag="VVR63_001813"
     CDS             3802..4356
                     /locus_tag="VVR63_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HEU6129798.1"
                     /translation="MVKVAVMLAQGFEEIEALTVVDVLRRANITCDMVGFEEQVTGSH
                     AIQVRADHVFDGDLSDYDMIVLPGGMPGSAHLRDNQTLIQELQSFEQEGKKLAAICAA
                     PIALNQAEILKNKRYTCYDGVQEQILDGHYVKETVVVDGQLTTSRGPSTALAFAYELV
                     EQLGGDAESLRTGMLYRDVFGKNQ"
     gene            4441..5004
                     /locus_tag="VVR63_001814"
     CDS             4441..5004
                     /locus_tag="VVR63_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEU6129799.1"
                     /translation="MKYHDYIWDLGGTLLDNYETSTAAFVETLALYGITQDHDSVYQA
                     LKVSTPFAIETFAPNLENFLEKYKENEARELEHPILFEGVSDLLEDILNQGGRHFLVS
                     HRNDQVLEILEKTSIAAYFTEVVTSSSGFKRKPNPESMLYLREKYQISSGLVIGDRPI
                     DIEAGQAAGLDTHLFTSIVNLRQVLDI"
     gene            5019..6965
                     /gene="gyrB"
                     /locus_tag="VVR63_001815"
     CDS             5019..6965
                     /gene="gyrB"
                     /locus_tag="VVR63_001815"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HEU6129800.1"
                     /translation="MTEEIKNLQAQDYDASQIQVLEGLEAVRMRPGMYIGSTSKEGLH
                     HLVWEIVDNSIDEALAGFASHIQVFIEPDDSITVVDDGRGIPVDIQEKTGRPAVETVF
                     TVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVHVHKNGKIHYQEYRRGHVVAD
                     LEVVGDTDRTGTTVHFTPDPEIFTETTIFDFDKLNKRIQELAFLNRGLQISITDKRQG
                     LEQTKHYHYEGGIASYVEYINENKDVIFDTPIYTDGEMDDITVEVAMQYTTGYHENVM
                     SFANNIHTHEGGTHEQGFRTALTRVINDYARKNKLLKDNEDNLTGEDVREGLTAVISV
                     KHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFSDFLMENPQIAKRIVEKGILAAKARV
                     AAKRAREVTRKKSGLEISNLPGKLADCSSNNPAETELFIVEGDSAGGSAKSGRNREFQ
                     AILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGAEFDVSKARYQKLVLMTDAD
                     VDGAHIRTLLLTLIYRYMKPILEAGYVYIAQPPIYGVKVGSEIKEYIQPGADQEIKLQ
                     EALARYSEGRTKPTIQRYKGLGEMDDHQLWETTMDPEHRLMARVSVDDAAEADKIFDM
                     LMGDRVEPRREFIEENAVYSTLDV"
     gene            7047..8774
                     /gene="ezrA"
                     /locus_tag="VVR63_001816"
     CDS             7047..8774
                     /gene="ezrA"
                     /locus_tag="VVR63_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HEU6129801.1"
                     /translation="MSNGQLIYLMVAIAVILVLAYVVAIFLRKRNEGRLEALEERKEE
                     LYNLPVNDEVEAVKNMHLIGQSQVAFREWNQKWVDLSLNSFADIENNLFEAEGYNHSF
                     RFLKASHQIDQIESQITLIDEDIAAIRNALADLEKQESKNSGRVLHALDLFEELQHRV
                     AENSEQYGQALDEIEKQLENIQSEFSQFVTLNSSGDPVEAAVILDNTENHILALSHIV
                     DRVPALVTTLSTELPDQLQDLESGYRKLIDANYHFVETDIEARFHLLYEAFKKNQENI
                     RQLELDNAEYENGQAQEEINALYDIFTREIAAQKVVENLLATLPTYLQHMKENNTLLG
                     EDIARLNKTYLLPETAASHVRRIQTELESFEAAIVEVTSNQEEPTQAYSVLEENLEDL
                     QTQLKDIEDEQISVSERLTQIEKDDINARQKANVYVNRLHTIKRYMEKRNLPGIPQTF
                     LKLFFTASNNTEDLMVELEQKMINIESVTRVLEIATNDMEALETETYNIVQYATLTEQ
                     LLQYSNRYRSFDERIQEAFNEALDIFEKEFDYHASFDKISQALEVAEPGVTNRFVTSY
                     EKTRETIRF"
BASE COUNT         2756 a         1641 c         1958 g         2734 t
ORIGIN      
        1 aaaagtagtg ttcttgagtt tgaaaattat cctatgtttg caggtgccaa atggcccttt
       61 ttttggtata attttttata atgaaaacga ttggtaatcg ctatgttgtg gtggatttag
      121 aggcaactag cacaggtagt aaggctaaaa ttatccaagt gggaattgtc gtgattgagg
      181 atggagaaat cgtcgatcac tatacgacgg atgtcaatcc acatgaaccc ttggatgctc
      241 atatcaaaga actgacagga ttgacagacc aacgtctggc gcaagcacct gatttttcgc
      301 aagttgccag aaaaatcttt gacttggtgg aggatgggat ttttgtagcc cataatgttc
      361 agtttgatgc taatctcttg gcggaaaatt tattttttga aggctatgag ctaagaaacc
      421 ctcgtgttga tacggtcgaa ttggcccagg tctttttccc tgaactggaa aaatatagct
      481 tgccgatttt gtgtcgagaa ttaggaattc ctcttaaaca cgcacacaca gccctttcag
      541 atgcccaagc tacagcagaa ttacttcttt ttttacggga aaagatgacc cagcttccta
      601 aaggtctctt ggaacgcttg ctggaaatgg ctgacgctct cctatatgag tcttacctgg
      661 ttattgagga aacttatcgc aaccaatcta tcctgagttc tccagacttg gtccaagttc
      721 aaggtctgta ttttaagaaa acggcagctt ctctggagct acgaaaacta tctcaagact
      781 tttctaaaaa tatttctctg ttgaaccttg aagtgaggga ggaacaagaa agttttgcta
      841 aagaggttgg cttgctattg aaagatgaac ctttctctct gattcaagcg ccgacaggga
      901 ttgggaaaac ctatggctat ctcttacccg ctttatctca atccaaagag cgacaaattg
      961 ttcttagtgt tccgacaaag attcttcaaa atcaaatcat ggaagaagaa ggtaaacgtc
     1021 tcaaggaagt gttccataca gatattcata gcttaaaggg accacaaaat tatctgaagt
     1081 tggatgcctt ttatcattcc ttgcaggaaa atgatgaaaa tcgcttattt agacgcttta
     1141 aaatgcaagt cttggtctgg cttactgaga cagagacagg agatttggat gaaatcgggc
     1201 aactctaccg ttaccaacat tttctagcag accttcgtca tgatgggaat ttatcatccc
     1261 agagcttatt tgtgacggaa gatttttgga aacgtagtca agaaagggca gagacttgca
     1321 agcttttagt gactaatcat gcctatctcg tgaccagact tgaagataat cctgaatttg
     1381 tcagtgaccg tttactgatt attgatgaag tccaaaagat tttgttagct ctagaaaatc
     1441 tgcttcaaga gacctacgat atacaatcta ttatcgattt aattgataag gctttagtag
     1501 gagaagaaaa cagggttcaa caacggatac tagaaagtat tcgctttgag tgtctctact
     1561 tgatagaaca atttcagtct ggtaaatcta ggaaaaatat cttagattct ctggacaatc
     1621 tccatcagta tttttcagaa ttagaagtgg aaggctttga tgagctggtt cgctatttta
     1681 cagctgaagg tgattactgg cttgaagtaa ctgaaacgag tcaaaagaaa attcagattt
     1741 cttctacaaa atcaggccgt actcttctgt cctctttact tcctgagagt tgccaagtct
     1801 tgggagtatc ggctactctt gagattagtc agagggtttc tttggcagac cttttaggct
     1861 atcctgaagc caaatttgtc aagattgaat ctcggggaaa acaggaacaa gaagtggtta
     1921 tggtcaaaga tttccctctg gtaacagaaa cctccttaga agtctatgcc agagaggtag
     1981 ctgctttact agtggaaatt caagctttcc agcaaccgat tttggttctc tttaccgcta
     2041 aagacatgct tctagcagta tcggatttac ttacagttag ccacttggcc cagtataaaa
     2101 atggggatgt tcatcagcta aagaaacgct ttgaaaaagg tgaacaacaa atcttgcttg
     2161 gtgcagcaag tttctgggag ggagttgatt tttcaagcca tccttctgtg attcaagttg
     2221 taccgaggct tcctttccaa aatcctcaag aacccttgac gaaaaagatt aatcaagaac
     2281 tgaatcaaga agggaaaaat gccttttatg attatcaatt gccaatggcc attattcgtt
     2341 taaaacaggc tttgggaaga agtatgagac gtgaatacca acgttcctta actcttattt
     2401 tggataggag aatcgtcgga aaacgatacg gcaaacaaat agtagcatct ctagcagaag
     2461 aagcgactgt taaaaccatc tctcgatccg aagttgacga ggctattgat agatttttta
     2521 atgaactttg ataaatagta ttgtatgaaa gtataaggtt agtacatatg aaacgttctc
     2581 tcgactctag agtcgattat agtttgctct tgccagtatt ttttctactg gtcatcggtg
     2641 tggtggctat ctatatagcc gttagtcatg attatcccaa taatattctg cccattttag
     2701 ggcagcaggt cgcctggatt gccttggggc ttgtgattgg ttttgtggtc atgctcttta
     2761 atacagaatt tctttggaag gtgaccccct ttctatatat tttaggcttg ggacttatga
     2821 tcttgccgat tgtattttat aatccaagct tagttgcatc aacgggtgcc aaaaactggg
     2881 tatcaataaa tggaattacc ctatttcaac cgtcagaatt tatgaagata tcctatatcc
     2941 tcatgttggc tcgtgtcatt gtccaattta caaagaaaca taaggaatgg agacgcacgg
     3001 ttccgctgga ctttttgtta attttctgga tgattctctt taccattcca gtcctagttc
     3061 ttttagcact tcaaagtgac ttggggacgg ctttggtttt tgtagccatt ttctcaggaa
     3121 tcgttttatt atcaggggtt tcttggaaaa ttattatccc agtatttgtg actgctgtaa
     3181 caggagttgc tggtttctta gctatcttta ttagcaagga cggacgagct tttcttcacc
     3241 agattggaat gccgacctac caaattaatc ggattttggc ttggctcaat ccctttgagt
     3301 ttgcccaaac aacgacttac cagcaggctc aagggcagat tgccattggg agtggtggct
     3361 tatttggtca gggatttaat gcttcgaatc tgcttatccc agttcgagag tcagatatga
     3421 tttttacggt tattgcagaa gattttggct ttattggctc tgtcctggtt attgccctct
     3481 atctcatgtt gatttaccgt atgttgaaga ttactcttaa atcaaataac cagttctaca
     3541 cttatatttc cacaggtttg attatgatgt tgctcttcca catctttgag aatatcggtg
     3601 ctgtgactgg actacttcct ttgacgggga ttcccttgcc tttcatttcg caagggggat
     3661 cagctattat cagtaatttg attggtgttg gtttgctttt atcgatgagt taccagacta
     3721 atttagctga agaaaagagc ggaaaagtcc cattcaaacg gaaaaaggtt gtattaaaac
     3781 aaattaaata aggagaaaat catggtaaaa gtagcagtta tgttagctca gggctttgaa
     3841 gaaattgaag ccttgacagt tgtagatgtc ttgcgtcgag ccaatatcac atgtgatatg
     3901 gttggttttg aagagcaagt aacgggttcg catgcaatcc aagtaagagc agatcatgtc
     3961 tttgatggag atttatcaga ctatgatatg attgttcttc ctggaggtat gcctggttct
     4021 gcacatttac gtgataatca gaccttgatt caagaattgc aaagcttcga gcaagaaggg
     4081 aagaaactag cagccatttg tgcggcacca attgccctca atcaagcaga gatattgaaa
     4141 aataagcgat acacttgtta tgacggcgtt caagagcaaa tccttgatgg tcactacgtc
     4201 aaggaaacag tagtggtaga tggtcagttg acaaccagtc ggggtccttc aacagccctt
     4261 gcctttgcct acgagttggt ggagcaacta ggaggggacg cagagagttt acgaacagga
     4321 atgctctatc gagatgtctt tggtaaaaat cagtaaaacg ggagttattc tctcgttttt
     4381 tatgtggaaa actcagggaa atcatcgctt ttttcataaa aaaatgctat aatgaagggt
     4441 atgaaatatc acgattacat ctgggattta ggtggaactt tactggataa ttatgaaact
     4501 tcaacagctg catttgttga aacattggca ctgtatggta tcacacaaga ccatgacagt
     4561 gtctatcaag ctttaaaggt ttctactcct tttgcgattg agacattcgc tcccaattta
     4621 gagaattttt tagaaaagta caaggaaaat gaagccagag agcttgaaca cccgatttta
     4681 tttgaaggag tttctgacct attggaagac attttaaatc aaggtggccg tcattttttg
     4741 gtctctcatc gaaatgatca ggttttggaa attttagaaa aaacctctat agcagcttat
     4801 tttacagaag tggtgacttc tagctcaggc tttaagagaa agccaaatcc cgaatccatg
     4861 ctttatttaa gagaaaagta tcagattagc tctggtcttg tcattggtga tcggccgatt
     4921 gatatcgaag caggtcaagc tgcaggactt gatacccact tgtttaccag tatcgtgaat
     4981 ttaagacaag tattagacat ataagaaaaa ggaataagat gacagaagaa atcaaaaatc
     5041 tgcaggcaca ggattatgat gccagtcaaa ttcaagtttt agagggctta gaggctgttc
     5101 gtatgcgtcc agggatgtac attggatcaa cctcaaaaga aggtcttcac catctagtct
     5161 gggaaattgt tgataactca attgacgagg ccttggcagg atttgccagc catattcaag
     5221 tttttattga gccagatgat tcgattactg ttgtggatga tgggcgtggt atcccagtcg
     5281 atattcagga aaaaacaggc cgtcctgctg ttgagaccgt ctttacagtc cttcatgctg
     5341 gaggaaagtt cggcggtggt ggatacaagg tttcaggtgg tcttcacggg gtggggtcgt
     5401 cagtagttaa tgccctttcc actcaattag acgttcatgt ccataaaaac ggtaagattc
     5461 attaccaaga ataccgtcgt ggtcatgttg ttgcagacct tgaggtggtt ggggatacag
     5521 atagaactgg aacaacggtt cacttcacac cggacccaga aattttcact gaaacaacaa
     5581 tctttgattt tgataaatta aataaacgga ttcaagagtt ggcctttcta aatcgcggtc
     5641 ttcaaatttc aattacagat aagcgccaag gtttggaaca aaccaagcat tatcattatg
     5701 aaggtgggat tgctagttac gttgaatata tcaacgagaa caaggatgta atctttgata
     5761 caccaatcta tacagacggt gagatggatg atatcacagt tgaggtagcc atgcagtaca
     5821 caacaggtta ccatgaaaat gtcatgagtt tcgccaataa tattcatacc catgaaggtg
     5881 gaacgcatga acaaggtttc cgtacggcac tgactcgtgt tatcaatgat tatgctcgta
     5941 agaataagtt actgaaagac aatgaagata atttaacagg ggaagatgtt cgcgaaggat
     6001 taactgcagt tatctcagtt aaacacccaa atccacagtt tgaaggacaa accaagacca
     6061 aattgggaaa tagcgaagtg gtcaagatta ccaatcgcct cttcagtgaa gccttctccg
     6121 atttcctcat ggaaaatcca cagattgcca aacgtatcgt ggaaaaaggg attttagctg
     6181 ccaaggctcg tgtggctgcc aagcgtgcgc gtgaagtcac acgtaaaaaa tctggtttgg
     6241 aaatttccaa ccttccaggg aaactagcag actgttcttc taataaccct gctgaaacag
     6301 aactcttcat cgtcgaagga gactcagctg gtggatcagc caaatctggt cgtaaccgtg
     6361 agtttcaggc tatccttcca attcgcggta agattttgaa cgttgaaaaa gcaagtatgg
     6421 ataagattct agctaacgaa gaaattcgta gtcttttcac agccatggga acaggatttg
     6481 gcgcagaatt tgatgtttcg aaagcccgtt accaaaaact cgttttgatg accgatgccg
     6541 atgtcgatgg agcccacatt cgtacccttc ttttaacctt gatttatcgt tatatgaaac
     6601 caatcctaga agctggttat gtttatattg cccaaccacc aatctatggt gtcaaggttg
     6661 gaagcgagat taaagaatat atccagccgg gtgcagatca agaaatcaaa ctccaagaag
     6721 ctttagcccg ttatagtgaa ggtcgtacca aaccgactat tcagcgttat aaggggctag
     6781 gtgaaatgga cgatcatcag ctgtgggaaa caaccatgga tcccgaacat cgcttgatgg
     6841 ctagagtttc tgtagatgat gctgcagaag cagataaaat ctttgatatg ttgatggggg
     6901 atcgagtaga gcctcgtcgt gagtttatcg aagaaaatgc tgtctatagt acacttgatg
     6961 tctaaaaaat agggagaagt agttcccttg gtctaaaaaa tatgatataa tcgttacgat
     7021 tgtttcaagt aaaaaaggag tttgatatgt ctaatggaca actaatttat ttaatggttg
     7081 caattgcagt cattttagtt ctggcttatg tagtggcaat ctttctacgt aagcgaaacg
     7141 aggggagatt agaggcgcta gaagaaagaa aagaagaact atacaatctt ccagtaaatg
     7201 atgaagtaga agctgtaaaa aatatgcact tgattggaca aagtcaagtg gctttccgtg
     7261 aatggaatca aaaatgggtc gatttatctc tcaactcttt tgccgatatt gaaaataatc
     7321 tctttgaagc agaaggctat aaccattcat ttcgttttct caaggccagt catcaaattg
     7381 accaaattga gagtcaaatt actttgattg acgaagatat tgcggcaatt cgcaatgctt
     7441 tggcagactt agagaagcaa gaatctaaaa atagtggtcg tgttcttcat gctttggatt
     7501 tatttgagga acttcagcat agagttgctg aaaattcaga acagtatggt caagccttgg
     7561 atgaaattga aaaacaatta gaaaatatcc aatctgaatt ttcacaattt gtaaccttga
     7621 attcatcggg tgaccctgtg gaagccgcag tgattttgga taatacagaa aatcacattt
     7681 tggccttaag tcatattgtg gatcgtgttc cagccttggt tacgacgctt tctacagaat
     7741 tgccagatca attacaggat ttggaatccg gttatcgtaa actaattgat gctaattatc
     7801 attttgttga aacggatatt gaagcgcgtt tccacttgct ttatgaagca ttcaagaaaa
     7861 accaagagaa tattcgtcag ttggaattgg ataatgccga atatgagaat ggacaggcac
     7921 aagaggaaat caatgccttg tatgatattt ttactcgaga aattgctgct cagaaagtag
     7981 tggaaaatct acttgcaact cttccaactt accttcaaca tatgaaagag aataatactt
     8041 tattgggaga agatattgca cgtttgaaca agacctattt acttcctgag acagctgcaa
     8101 gccatgttcg tcgtattcag acagaattag agagttttga ggcagctatt gttgaggtaa
     8161 cttcaaatca agaagaacca acccaagctt attcagttct tgaagaaaat cttgaggatt
     8221 tacaaactca actaaaagat attgaagatg agcaaatttc agttagtgag cgcctgacac
     8281 aaattgagaa agatgatatt aatgcacgtc aaaaggccaa tgtttatgtc aatcgtctcc
     8341 atactatcaa gcgatacatg gaaaaacgca atctgccagg tattccacaa actttcttga
     8401 agttattctt tacggcaagc aataataccg aggatttaat ggttgagtta gaacaaaaaa
     8461 tgattaacat tgaatctgtt acccgagttc ttgaaattgc aacgaatgat atggaagctt
     8521 tagaaacgga aacttataat attgtacaat atgcaacttt gacagagcaa ctcttgcaat
     8581 attctaaccg ctatcgctca tttgatgaac gcattcaaga agcatttaac gaagctttag
     8641 atatttttga aaaagaattt gattatcacg cttcatttga caagatttct caagcattgg
     8701 aagtggcaga gcctggtgta accaatcgct ttgttacctc atatgagaaa acacgtgaaa
     8761 cgattcgttt ttaataaaag aaaaagattt tattgtgtga ggagcagaat caaatctttt
     8821 tctatagttg tggggagatt tacttcattt tctcctgaga ttgagttttt acccagccga
     8881 tttatccacc acctcaaaac agtgttttat actcttcgaa aatctcttca aatcacgtca
     8941 gcgtcgcctt accgtactca agtacagcct gaggctagct tcttagtttg ctttttgatt
     9001 ttcatttagt attaaagtga tttcgtcagt cttatctgca gcttcaaatc tgtactttga
     9061 gtaacttggt aaccgtccaa taacgaagt
//
LOCUS       DAVHTH010000067         8847 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.067, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000067 DAVHTH010000000
VERSION     DAVHTH010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8847)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8847)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8847
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.067"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            complement(118..915)
                     /locus_tag="VVR63_001817"
                     /pseudo
     CDS             complement(118..915)
                     /locus_tag="VVR63_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436304.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            1181..1417
                     /locus_tag="VVR63_001818"
     CDS             1181..1417
                     /locus_tag="VVR63_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecX"
                     /protein_id="HEU6129802.1"
                     /translation="MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVR
                     YGIGCRKDFIVYHYRVAYRLYLEKLVMNRGFISC"
     gene            1648..2934
                     /locus_tag="VVR63_001819"
     CDS             1648..2934
                     /locus_tag="VVR63_001819"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HEU6129803.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSANAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPEKISVIGNGMVVNPKSLVKELSYLHEEGVTTDNLRISDRA
                     HVILPYHIELDRLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFRERL
                     ERNLAEKNRLFEKLYDSKAIVFDDIFEEYYEYGQQIKKYVIDTSVILNDALDNGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKIDKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDTVKICVAYDLDGQRIDYYPASLEQLKRCKPIYEELPGWSEDITGVRNLEDLPEN
                     ARNYVRRVSELVGVRISTFSVGPGREQTNILESVWS"
     gene            3135..3602
                     /locus_tag="VVR63_001820"
     CDS             3135..3602
                     /locus_tag="VVR63_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HEU6129804.1"
                     /translation="MYYTLEEKEVFMREALREAEIALEHDEIPIGCVIVKDGEIIGRG
                     HNAREELQRAVMHAEIMAIEDANLSEESWRLLDCTLFVTIEPCVMCSGAIGLARIPNV
                     VYGAKNQKFGAAGSLYDILTDERLNHRVEVEIGILEDECAAIMQDFFRNRRKK"
     gene            3635..3728
                     /gene="ffs"
                     /locus_tag="VVR63_001821"
     ncRNA           3635..3728
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="VVR63_001821"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(3811..4952)
                     /locus_tag="VVR63_001822"
                     /pseudo
     CDS             complement(3811..4952)
                     /locus_tag="VVR63_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518706.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
     gene            complement(5007..6077)
                     /locus_tag="VVR63_001823"
     CDS             complement(5007..6077)
                     /locus_tag="VVR63_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000401842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction enzyme HsdR N-terminal
                     domain-containing protein"
                     /protein_id="HEU6129805.1"
                     /translation="MEIDKVKADLKQVGKRVADLSQSITNEEQTKNAFIMPFFQALGY
                     DIFNPLEFVPEFTADVGIKKGEKVDYAIILDGEPQILIECKSITENLTKHDSQLFRYF
                     VTTKSKFGILTNGREYKFFTDLDEPNKMDTTPFLTIDVTDIKENQFTEIIKFHKENFD
                     IDNIVSSASELKYLNNLKAFLTENITTPSDSFLRYLTSEIYEGRVTQNILTTFSPIIV
                     KGFNQFITERVNEKLSAALNTSVETKVTTDIPKVEAEAEEIVEVTDEIITTPAELEVY
                     TVVKMLARDVVSPERVFYRDNRSYFNVLVDDNIKKWVLRYRSNSKKSTIEIRDKGIFP
                     VSTPLEVANYANEILEVIKKFS"
     gene            complement(6094..6474)
                     /locus_tag="VVR63_001824"
     CDS             complement(6094..6474)
                     /locus_tag="VVR63_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HEU6129806.1"
                     /translation="MTLAKLCEEYQVELCLFDGSNWHNSGFYNPDTNVLAIDHNLTPE
                     QQIQVALHELGHKDHTRSEHQNARLRCENEADRNMIHHLVKDALENLDDPTEFDYLKF
                     MSYYNLKTMTNEIMVKEEYLALVN"
     gene            complement(6487..6750)
                     /locus_tag="VVR63_001825"
     CDS             complement(6487..6750)
                     /locus_tag="VVR63_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEU6129807.1"
                     /translation="MYRLDIDKKALKQLKKLDTPTRKQILSWLAKNIENTTNPRQHGK
                     ALKANLAGYWRYRVENYRIICDIQDDKLVVLAVEIAHRRDVYK"
     gene            complement(6750..6983)
                     /locus_tag="VVR63_001826"
     CDS             complement(6750..6983)
                     /locus_tag="VVR63_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6129808.1"
                     /translation="MTITINFTEKNSYITDYLNKHGIDTTTMDFDDFMALMEDIEDAR
                     AADQAYMEYLADPATYTMDEVLDELGLTREDIA"
     gene            complement(6983..7351)
                     /locus_tag="VVR63_001827"
     CDS             complement(6983..7351)
                     /locus_tag="VVR63_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU6129809.1"
                     /translation="MFETFEKIKELAKKRGKALGQVEEDLGYGRNTLYKIKNSTPNAE
                     RIAEIANYFNVSTDYLLGRTDNPAIAGSDEFAQVNGQIIDLRKAAANTMLFDGKPLNE
                     DDIDFITSVLSAHFKSKGER"
     gene            7923..8114
                     /locus_tag="VVR63_001828"
     CDS             7923..8114
                     /locus_tag="VVR63_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001112859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEU6129810.1"
                     /translation="MPDIANGRERVIAFLKEKGIKKATLAVAYGFKRQEVTNILSGTT
                     KGPRANSFILQVIEDYGIE"
     gene            8137..8340
                     /locus_tag="VVR63_001829"
     CDS             8137..8340
                     /locus_tag="VVR63_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001247546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6129811.1"
                     /translation="MRPKRYPYSGQKESTFVKADPELVEKLLRNTSFLECLQKKPINF
                     QIDSEEFKRLSYEAIHDTSQVTQ"
     gene            complement(8495..8662)
                     /locus_tag="VVR63_001830"
     CDS             complement(8495..8662)
                     /locus_tag="VVR63_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzC family protein"
                     /protein_id="HEU6129812.1"
                     /translation="MANTPIKPGTDNQKPGRYVEVGPRGGKVTNGHTATIGKGDRLPP
                     TSAKGNGWKKV"
     gene            8682..8847
                     /locus_tag="VVR63_001831"
                     /pseudo
     CDS             8682..8847
                     /locus_tag="VVR63_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="autolysin"
BASE COUNT         2522 a         1382 c         1862 g         3081 t
ORIGIN      
        1 atatcaaaaa gaacctcaaa aaggtattac caagttgcaa taccttttac gaggctcttt
       61 tctcttgttc ttgtttcaat tgactatatt agaggcgaga catttttcgg ttctttgtca
      121 actgtagtgg gttgaagaaa gcgaagatct agaaaggaca aatttcgtcc tttctttttt
      181 gaagttttca aagttcctaa aaccaaaggc attgtgcttg ataagtttga tgagattatt
      241 ggtggcttcc agtttggcgt tggaataagg taattgaagg gcgttgacga ttttctcttt
      301 atctttgagg aaggttttaa acaaagtctg aaacagaggt ggaaaagcaa gagctgatag
      361 agattatagt ggtgtttcaa gtcttcggaa tagctcaaaa gtttatctag aatttcttta
      421 ttagtcaagt gcatacgaaa agtagggcga taaaatcgtt tatcactcag tttctgacta
      481 tcttgttgaa tgagcttcca gtagcgcttg atagccttgt attcatggga tttcggatga
      541 tggcttgtgt tctgctctca agaacagtta tgatattgag tttatcaaag tcctgagcaa
      601 taaagctcat ctccatctcc cgattgaaac agtcactccc cggactgttt caacgtccta
      661 ggacataatc tcaggaagac gcgaaaaatc atgctcaaag tgaaaattat tgatcttgcg
      721 aatgacagtt gaagttgaaa tagacaactg atgatcaatg tcggtcatag aagtcttttc
      781 aattagcttc tgagcaatct tttggttgat gatacaagga atttgatgat tcttcttgac
      841 gatagaagtc tcagcgagct ccatttttga gcaatgatag cacttaaaac ggccttttct
      901 aagaagaatt ctagtttgaa tttttttata ctagaaaatc agaaccataa tacctatata
      961 aaaatattat agttctaata ggatttaccc aaaagtttta aggcggtctt tttagaactt
     1021 taattttttg aaatttaggt agcaaatttg tttctatttt gtcaactttt cctattttta
     1081 tcttgttgag gctggtattt taacaattca ggaattgata gtgaatgtgt aaaatttttt
     1141 gttagaataa gtttataaaa aagaaaagga gtatttgatt atgttacaaa aaatttatga
     1201 gcagatggct aatttctatg atagtattga agaagagtat ggtcctacat ttggtgataa
     1261 ttttgactgg gaacatgttc attttaaatt tttaatttat tatttagtga gatatggcat
     1321 tggttgtcgt aaggatttta ttgtttacca ttatcgtgtt gcttatcgtt tgtatcttga
     1381 aaaattggta atgaatcggg ggtttatttc ttgttgaggt aattttagta aatttccgaa
     1441 ctaatttact cttttatgga aagatgatag taaatagcta gtaatttttc taaatcattt
     1501 tttaatagtt ggaaatagca aatctttcta ttgtttcttc ttgataaaaa ggcgattttt
     1561 tattataata aattgtaaga tataattgca ggtgagagtc ctgccatgta tgtgagaaag
     1621 gaagagcctg agggctcaga caagattatg acttcagttg ttgttgtagg tacccaatgg
     1681 ggtgatgaag gtaaagggaa gattacagac ttcctttcag cgaatgcaga agtgattgca
     1741 cgttaccaag gtggtgataa tgctggtcac acgattgtga ttgacggtaa gaaatttaag
     1801 ttgcacttga ttccatctgg gattttcttc cctgaaaaaa tatctgtcat tgggaatggt
     1861 atggttgtaa atcctaaatc tcttgtaaaa gagttgagct atcttcatga ggaaggtgta
     1921 acaactgata acttgcgtat ttctgatcgt gcgcatgtta ttttgcctta tcatatcgag
     1981 ttggatcgct tgcaagaaga agctaagggc gacaataaga ttggtacgac aattaaggga
     2041 attggtccag cttatatgga caaggctgct cgtgttggaa ttcgtattgc agatctttta
     2101 gataaagata ttttccgtga gcgtttagaa cgtaaccttg ctgaaaagaa tcgtcttttt
     2161 gaaaaattgt atgacagtaa agcgattgtt ttcgatgata tttttgaaga atattacgaa
     2221 tatggtcaac aaatcaagaa atacgtgata gatacatctg ttatcttgaa tgatgcgctt
     2281 gataatggca aacgtgtgct ttttgaaggt gcacaaggtg ttatgctaga tatcgaccaa
     2341 ggtacttatc catttgttac gtcatcaaac cctgtagctg gtggtgtgac aattggttct
     2401 ggtgtcggtc caagcaagat tgacaaggtt gtaggtgtat gtaaagctta tacgagtcgt
     2461 gtaggagatg gtcctttccc aactgagttg tttgatgaag tgggagaacg tatccgtgaa
     2521 gtgggtcatg aatatggtac aacaactggt cgtccacgtc gtgtaggttg gtttgactca
     2581 gttgtgatgc gtcatagccg tcgtgtttct ggtattacta acctttcttt gaactctatt
     2641 gatgttttga gcggtttgga tactgtgaaa atctgtgtgg cctatgatct tgacggtcaa
     2701 cgtattgact actatccagc tagtcttgag caattgaaac gttgcaagcc tatctatgaa
     2761 gagttgccag gttggtcaga agatattacc ggagttcgca atttggaaga tcttcctgag
     2821 aatgcgcgta actatgttcg tcgtgtgagt gaattggttg gcgttcgtat ttctactttc
     2881 tcagtaggtc ctggtcgtga acaaacaaat attttagaaa gtgtttggtc ctaagagatt
     2941 tttaagattt gtttaagata ggtcgggtat actatagaca gttacaagaa gacctcctaa
     3001 cttgttgtaa caaatatcct aaacttttct ttttcataat aatctcccta tagagtcacc
     3061 gcattcggtg gcttcttttg tgttgggatt catgatataa taataaaatc gataagtagg
     3121 aaaagagaaa agagatgtat tatacgcttg aagaaaaaga agtctttatg agggaggctt
     3181 tgagagaggc tgagattgct cttgaacacg atgaaattcc aattggttgt gtgattgtca
     3241 aagatgggga aatcattggt cgtgggcata atgcgcgtga ggaattacag cgagcggtta
     3301 tgcatgcgga aattatggct atagaggatg cgaacttgag tgaggagagc tggcgcttgc
     3361 tggattgcac actttttgtg accattgaac cttgtgtcat gtgtagtggg gcgattgggc
     3421 ttgcccgcat tccaaatgtg gtctatgggg ctaaaaacca gaaatttggc gctgctggga
     3481 gtttgtacga tatcttgaca gatgagcgtc tcaatcatcg tgtggaggtt gaaataggaa
     3541 ttttggaaga tgaatgcgca gctatcatgc aggatttttt tagaaataga cggaaaaaat
     3601 aattttgctt ttaaaatgaa taggaatgtg atataataaa tagtggagca acagttctgc
     3661 gtgaagcggg tcaggggagg aatccagcag ccctaagcga tttgaattgt gtgctctttt
     3721 ttcgtgcact ttaaaaaccc tttaaaatca acactttaag gggtttttgt ttgtcttgta
     3781 taagaaaaag gggcagacga ggggcacaat ttaaaatttt atcttgtcta acttgctaga
     3841 tatgtctgat accatttttt gagtaacgtg agaataaatc tctagtgtgg tctttgagtc
     3901 actatgccct actctgtcca tgatggcagt caagggaatg cccagctcag caagtaggga
     3961 tatgtgagaa tgtctaaatg tatgtgtagt tatgtttttt tctatgccga ttttttgacc
     4021 atgtcttttc aatgcacaaa taaccctggc atttgttatt ggttctccta gagtattgat
     4081 gaaaataaaa tctgtatcaa atccatttgt cgcattctct attatttgct ctttgataat
     4141 atctaacact ttttgaggtg ctgttataac cctatcggac ttgattgtct ttggtgtagt
     4201 tctctctttt tgtctgaaat cgtatgtatg cttgatgtga atagtctttt tagaaaaatc
     4261 tatatcttcc ttgtagttta aggctgccag ctctccatac ctcatgccag taagaaaaag
     4321 aactttagct attcggatat actttgtaat tcgataatca catagggcct cgtcttttaa
     4381 attttggatg aataacttaa actctttttg gtctaagtat tttgtatttt tctttctgag
     4441 ttcgtcggat gtaattactt ttctaggcgt ttcaacaaat agcatttcat ttgtatcaat
     4501 ataattcatt ctgatagcaa atttcattat ctgattgagc ttgaatttga ttttagaaac
     4561 atagttatga gatctcccat cttgtaatag ttgatctatt actttttgta ataaacgtct
     4621 atcaaatttc taactaggta gtcgccctct atctgcttta aaatctcttt ttttacattc
     4681 tttgaagcgt agacggttga gttttttacg ccgtgtttcc aattctcctc aaattcttca
     4741 tatagttttt caaaagttat attagaaaca gaatgttgtt tttctcctaa cttttgtttt
     4801 atcttttcct gaagtaaaat cgcagcttga tttcttgctt ggggagtttt tttctccatc
     4861 gttactgaga ctttttttaa tttctcagta tatggatctt tgtatctctc aaaaaattta
     4921 tatttgccgt ttggcaattc ttccatccac attgatttta cctcactttt ttgataaaat
     4981 gggtatagta aagagggctt tttttattat gagaatttct tgattacttc taaaatttca
     5041 ttggcataat ttgcgacttc gagaggggta gacaccggga agatgccttt atcacggatt
     5101 tcgatagtgc ttttttttga atttgaacga taacgtaata cccatttttt gatgttatcg
     5161 tcaaccaaaa cattgaaata gctacggtta tctctgtaaa atacacgttc tggagaaact
     5221 acatccctag caagcatttt aacaacagta taaacttcta attcagcagg agttgtgata
     5281 atttcgtcag ttacttcgac aatctcttca gcttcagctt caacttttgg aatatcggtt
     5341 gttactttgg tttcaacgct tgtattaagt gcagcactta atttttcatt aactcgctct
     5401 gtgatgaatt gattaaaccc tttcacaata atgggagaaa atgtcgttaa gatattttga
     5461 gtaacacgcc cttcatagat ttcagaagtt agatatctga ggaagctatc tgacggtgta
     5521 gtgatatttt cagtaaggaa cgctttaaga ttgttgaggt atttcaattc agaagctgat
     5581 gaaacaatat tatcaatatc aaaattctct ttgtggaatt tgatgatttc agtaaattga
     5641 ttttctttga tatcagtcac atcgattgtt aagaatggag ttgtgtccat tttatttggc
     5701 tcatctaaat cagtaaagaa tttatattct ctaccatttg tcaagatacc gaattttgat
     5761 ttagtagtta cgaaatatct gaatagttga gagtcgtgct tagtaaggtt ttctgtaatt
     5821 gatttacatt caattaggat ttgaggctcg ccatccaaaa tgatcgcata gtcgactttt
     5881 tcgccttttt taatgcccac gtcggcagta aattccggga caaattcaag tggattgaag
     5941 atatcatatc caagcgcttg gaagaacggc ataatgaagg cattctttgt ttgttcttca
     6001 ttcgtaatgc tttggctgag gtctgctaca cgtttgccga cttgttttaa atcggctttt
     6061 actttatcaa tttccatatt gatactcctt tttttaattt actaatgcta aatactcttc
     6121 tttaaccatg atttcatttg tcatggtttt tagattgtag taagacatga atttgaggta
     6181 atcaaactct gtggggtcgt ctaagttttc tagagcgtct tttacgagat gatggatcat
     6241 attcctatca gcttcgtttt cacagcgtag acgggcgttc tggtgctctg agcgtgtgtg
     6301 gtctttgtgt ccaagttcgt gtagggcgac ttggatttgt tgttcaggag tcaagttgtg
     6361 gtcaatagcg agcacgtttg tgtctggatt gtagaaaccg ctattgtgcc agtttgaacc
     6421 gtcgaagaga caaagttcta cttgatattc ttcgcagagt ttagcgagtg tcatagttct
     6481 ccttcgttat ttatagacat ctctgcggtg ggcgatttcc acggctagga cgactagttt
     6541 atcgtcttgg atatcacaga tgatgcggta attctctact ctgtatcgcc agtaacctgc
     6601 aaggttggct tttagtgctt ttccgtgttg tcgtggattg gtcgtgtttt caatgttttt
     6661 agcaagccag gataggattt gttttctggt tggggtatct agttttttaa gttgcttgag
     6721 agctttttta tcaatatcta gccgatacat taagcaatat cctctcgagt tagtcctagt
     6781 tcatccaaga cctcatccat ggtataagta gctgggtcgg ctaaatactc catataggct
     6841 tggtcggctg ctcgtgcgtc ttcgatatct tccatgagtg ccatgaagtc gtcaaaatcc
     6901 atggtcgttg tgtcgatacc gtgtttgttt aggtagtccg taatgtagga atttttttct
     6961 gtgaagttga tagtgatagt cattagcgtt ctcctttgct tttgaagtgg gcggatagga
     7021 cggatgtaat gaagtcgata tcatcttcat ttagtggttt cccgtcaaat aacatggtgt
     7081 tggctgctgc tttgcgtaag tctatgattt gtccgtttac ttgggcaaat tcatcactcc
     7141 cagcgatagc agggttatct gttcgtccga gcaggtagtc ggtggatacg ttgaaataat
     7201 tagcaatttc tgcgatacgt tcagcgtttg gcgtagaatt ttttatctta tagagtgtat
     7261 ttctaccata acctaagtct tcttctactt gtccaagagc ttttccacgc ttttttgcca
     7321 attcttttat tttttcaaat gtctcaaaca ttgttaaatc aacctttcta agacatcaca
     7381 aaaaaaattt aacaaatttg gtgtaaaaag gttgactaat tatcccaaaa ggtgtaaaat
     7441 gttttttgta agtgataaac aactaaaaaa acaactaaga aataaattat aaaaatgttt
     7501 tggcgaacgg tatttataga tttattggtg tttttattat gctttaattt tagccgattt
     7561 ggtgtaagtt gtcaagtata atgcagaaaa atagttacat ttttagttgt ttcttattta
     7621 caaataagta aagaggagga acgtgctgat ggtaagtatt cttaaaaatt tagaacaaga
     7681 aaaagaccac cttgaaaaag tcattaaggt agtcagcgct ggtggtaaat ttctgagatt
     7741 gccatatcaa aaaagtcacg ctcgattagt gagaatctga aattgatttc tcaaaatctt
     7801 taccatcatc gtagatgtcg cgtttgcttg ctttgagtaa atattcttta aaagtcataa
     7861 ggttaactcc tttctgctta tattatagca gaaaaagaag aaagaaaaag aaaggagaaa
     7921 atatgccaga tatcgcaaac ggtcgcgaaa gagttattgc tttcttgaaa gagaaaggca
     7981 ttaaaaaagc aactctagcg gttgcttacg gctttaaacg acaggaagtg acaaacattc
     8041 taagtggaac gactaaaggt ccacgagcga acagtttcat tcttcaggtt attgaagatt
     8101 atgggattga gtaggaaaga tttgaggagt aggaaaatga gaccaaaacg atatccgtat
     8161 agtggacaaa aagagtccac ctttgtaaag gcagaccctg agttagttga aaaactttta
     8221 agaaacacta gttttcttga gtgtttacaa aaaaagccta tcaattttca gatagactca
     8281 gaagaattta agcgtcttag ctatgaagcc attcatgata cttctcaagt aactcaatag
     8341 gaggaaggaa taaaatgatt caccattata taactcacta tgccagcaat gggaaagatt
     8401 acgccgaagc atggattcaa attgattttt tgggaatgtg cttttgtgta tggaaaaagc
     8461 gtacaaccat tgaacgattg tacgcaaacg aagattagac ttttttccaa ccgttgcctt
     8521 tagcagatgt cggagggagc cgatcacctt ttccgatagt tgcggtatga ccattagtaa
     8581 cttttccgcc acgaggtcct acctctacat agcgaccagg tttctgatta tctgttccag
     8641 gttttattgg agtatttgcc atactatctc ctcctttcta taagtttgag aaaatcaacg
     8701 gtatctggta ttatttcgat ggctcaggct atatgctttc agaccgctgg aagaagcaca
     8761 cagacggtaa ttggtactac tttgaccaat caggcgaaat ggccacaggc tggaagaaaa
     8821 tcgctgacaa gtggtactat tttgatg
//
LOCUS       DAVHTH010000068         8736 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.068, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000068 DAVHTH010000000
VERSION     DAVHTH010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8736)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8736)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8736
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.068"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            complement(1..171)
                     /locus_tag="VVR63_001832"
                     /pseudo
     CDS             complement(1..171)
                     /locus_tag="VVR63_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(217..450)
                     /locus_tag="VVR63_001833"
     CDS             complement(217..450)
                     /locus_tag="VVR63_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEU6129813.1"
                     /translation="MTEKEIFDRIVTIIQERQGEDFVVTESLSLKDDLDADSVDLMEF
                     ILTLEDEFSIEISDEEIDQLQSVGDVVKIIQGK"
     gene            complement(456..1448)
                     /gene="plsX"
                     /locus_tag="VVR63_001834"
     CDS             complement(456..1448)
                     /gene="plsX"
                     /locus_tag="VVR63_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HEU6129814.1"
                     /translation="MKKIAVDAMGGDYAPQAIVEGVNQALSDFSDIEVQLYGDEAKIK
                     PYLTATERVSIIHTDEKIDSDDEPTRAIRNKKNASMVLAAKAVKDGEADAVLSAGNTG
                     ALLAAGFFIVGRIKNIDRPGLMSTLPTVDGKGFDMLDLGANAENTAQHLHQYAVLGSF
                     YAKNVRGIAQPRVGLLNNGTESSKGDPLRKETYELLAADESLNFIGNVEGRDLMNGVA
                     DVVVADGFTGNAVLKSIEGTAMGIMGLLKTAITGGGLRAKLGALLLKDSLSGLKKQLN
                     YSDVGGAVLFGVKAPVVKTHGSSDAKAVYSTIRQIRTMLETDVVAQTAREFSGE"
     gene            complement(1445..2215)
                     /gene="recO"
                     /locus_tag="VVR63_001835"
     CDS             complement(1445..2215)
                     /gene="recO"
                     /locus_tag="VVR63_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000616164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HEU6129815.1"
                     /translation="MIQSITSQGLVLYNRNFREDDKLVKIFTEQVGKRMFFVKHAGQS
                     KLAPVIQPLVLARFLLRINDDGLSYIEDYHEVMTFPKINSDLFVMAYATYVAALADAS
                     LQDNQQDAPLFAFLQKTLELMEAGLDYQVLTNIFEIQILTRFGISLNFNECVFCHRVG
                     QAFDFSFKYGACLCPEHYHEDKRRCHLNPNIPYLLNQFQAIDFETLETISLKPGIKQE
                     LRQFMDQLYEEYVGIHLKSKKFIDSLADWGQLLKEEKK"
     gene            complement(2212..3381)
                     /locus_tag="VVR63_001836"
     CDS             complement(2212..3381)
                     /locus_tag="VVR63_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEU6129816.1"
                     /translation="MDLTKRFNKQLDKIQVSLIRQFDQAISEIPGVLRLTLGEPDFTT
                     PDHVKEAAKRAIDQNQSYYTGMSGLLTLRQAASDFVKEKYQLDYAPENEILVTIGATE
                     ALSATLTAILEEGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTENGFVLTPEMLEKAI
                     LEQGDKLKAVILNYPANPTGITYSREQLEALAAVLRKYEVFVVCDEVYSELTYTGEAH
                     VSLGTMLRDQAIIINGLSKSHAMTGWRLGLIFAPATFTAQLIKSHQYLVTAANTMAQH
                     AAVEALTAGKNDAEPMKKEYIQRRDYIIEKMTALGFEIIKPDGAFYIFAKIPAGYNQD
                     SFAFLKDFAQKKAVAFIPGAAFGRYGEGYVRLSYAASMETIKEAMKRLEEYMREA"
     gene            3530..4540
                     /locus_tag="VVR63_001837"
     CDS             3530..4540
                     /locus_tag="VVR63_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family putative sulfate export transporter"
                     /protein_id="HEU6129817.1"
                     /translation="MSFLSKNGAGILVCLLISIVSWYLGGFFPVIGAPVFAIFMGMLL
                     HPFLSSYKQLDVGLTFSSKKLLQYAVILLGFGLNISQVFAVGQSSLPVILSTISIALI
                     VAYLFQRFFALDTKLATLIGVGSSICGGSAIAATAPVIHAKEKEVAQAISVIFFFNVL
                     AALIFPTLGTWLHLSSDGFALFAGTAVNDTSSVTATASAWDSLYQTNTLESATIVKLT
                     RTLAIIPITLFLSYWQSREQKNKQGLQLKKVFPLFILHFILASLLTTLLTSLGVSSSF
                     FTPLKQLSKFLIIMAMSAIGLKTNLVAMVKSSGKSIVLGAVCWIAIILTSLGMQTLIG
                     IF"
     gene            complement(4700..4780)
                     /locus_tag="VVR63_001838"
                     /pseudo
     CDS             complement(4700..4780)
                     /locus_tag="VVR63_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(4815..5252)
                     /locus_tag="VVR63_001839"
     CDS             complement(4815..5252)
                     /locus_tag="VVR63_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HEU6129818.1"
                     /translation="MSQEFINPSDGVIRQYLATSKTLAVVGLSDREETTSNRVTKEMQ
                     ARGYKIIPVNPKAAGGEILGEKAYASLAEIPFPVDIVNVYRRSEFLPDVARDFLKADA
                     KIFWAQLGLESLEAKEILRDGGCDDIVMNRCIKREHTRLIEEA"
     gene            complement(5337..7970)
                     /gene="polA"
                     /locus_tag="VVR63_001840"
     CDS             complement(5337..7970)
                     /gene="polA"
                     /locus_tag="VVR63_001840"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HEU6129819.1"
                     /translation="MDKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQ
                     LMLSHLLERVEPSHILVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDH
                     MGIRHYELAQYEADDIIGTLDKLAEQDGFDITIVSGDKDLIQLTDEHTVVEISKKGVA
                     EFEAFTPDYLMEEMGLTPAQFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEHGSLEG
                     IYENIDGMKTSKMKENLINDKEQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGK
                     FYDEMGFKQLKQALNMSSADVAEGLDFTIVDQISQDMLSEESIFHFELFGENYHTDNL
                     VGFAWSCGDQLYATDKLELLQDPIFKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAF
                     DIRLAKYLLSTVEDNEIATIASLYGQTYLVDDETFYGKGVKKAIPEREKFLEHLACKL
                     AVLVETEPILLEKLSENGQLELLYDMEQPLAFVLAKMEIAGIMVKKETLLEMQAENEL
                     VIEKLSQEIYELAGEEFNVNSPKQLGVLLFEKLGLPLEYTKKTKTGYSTAVDVLERLA
                     PIAPIVKKILDYRQIAKIQSTYVIGLQDWILADGKIHTRYLQDLTQTGRLSSVDPNLQ
                     NIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIELRVLAHISKDEHLIKAFQEGADIH
                     TSTAMRVFGIERPDNVTANDRRNAKAVNFGVVYGISDFGLSNNLGISRKEAKAYIDTY
                     FERFPGIKNYMDEVVREARDKGYVETLFKRRRELPDINSRNFNIRGFAERTAINSPIQ
                     GSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVPKSELVEMKKLVKQTMEEA
                     IQLSVPLIADENEGATWYEAK"
     gene            complement(8579..>8736)
                     /locus_tag="VVR63_001841"
     CDS             complement(8579..>8736)
                     /locus_tag="VVR63_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000603336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6129820.1"
                     /translation="GRAEGCEQGREEGLEEGLKVGLVNLVRQGLLTPEVASEQLGMTV
                     AEFESLL"
BASE COUNT         2449 a         2205 c         1589 g         2493 t
ORIGIN      
        1 ttctcaacct tgcttctctc cttagatagc gcatgattac aggctttatc ttcaactgtt
       61 agcggcttga gtttgctgga tttacgtgga agtttgtgct tgaggatata tcttcatgag
      121 cccttgataa ccactgtcag ccaagatttt accagcttgt ccgatatttc tcatttctaa
      181 aaaccatcta cttccgttga cttggaactc cgattgctat tttccttgaa tgattttaac
      241 cacatctcct acactttgga gttggtcaat ttcctcatcg ctgatttcga tactaaattc
      301 atcttccaga gtcaagataa actccatcaa gtcaacagaa tccgcatcca aatcgtcttt
      361 cagactcaag gattctgtca cgacaaagtc ctctccctgt cgctcttgga taatggtcac
      421 aatacggtca aaaatttctt tttctgtcat ctcttttatt ctcctgaaaa ttcacgcgca
      481 gtctgggcaa ccacgtctgt ttctagcatg gtacggatct gacgaatcgt actataaaca
      541 gccttggcat cgcttgagcc atgagtcttg acaacaggtg ccttaacacc aaacaagacc
      601 gctccaccaa catctgaata attgagctgt tttttcaaac cactgaggct gtccttgaga
      661 aggagggcac ctagtttcgc tcgaagacca ccacctgtaa tagctgtctt gagcaagccc
      721 atgattccca tagctgtccc ttcgatggat ttgagcacag cgtttcccgt gaaaccatct
      781 gccacaacaa catctgcaac gccattcatc aaatcacgcc cttccacgtt tccgataaag
      841 ttcaaacttt catcagccgc cagtaattca taagtttcct tacgaagcgg gtcgcccttg
      901 ctactctctg ttccgttgtt gagcaaacca acgcgtggtt gcgcaatgcc acggacattt
      961 ttagcataga aggaacctag aaccgcatat tgatggaggt gctgggctgt attttctgca
     1021 ttggcaccaa ggtctagcat gtcaaaacct tttccatcaa cggtaggcaa ggtagacatg
     1081 agtccaggac ggtcgatatt cttgatacga cccacgatga agaatcctgc tgccaacaag
     1141 gcacctgtat tcccagccga aaggacagcg tctgcttcac catctttgac agccttggct
     1201 gccaatacca tactggcatt tttcttattc ctaatagctc tcgtaggttc atcatccgaa
     1261 tcaatcttct catccgtatg gataatgctg acgcgctctg tcgctgtcag atagggcttg
     1321 attttagctt catctccgta aagttgaacc tcgatatctg aaaagtcaga tagggcttga
     1381 ttgacaccct caacaatggc ctgaggtgcg taatcgcccc ccatggcatc tactgcgatt
     1441 tttttcattt cttttcctct tttagtaatt gtccccagtc tgctagggaa tcaataaatt
     1501 tctttgattt taggtgaatc ccaacgtact cttcatataa ttgatccata aattggcgta
     1561 gctcttgctt gattccaggc ttgagcgaaa tggtctccaa agtctcaaaa tcaatagctt
     1621 gaaattgatt gagcagatag gggatattgg gattgagatg acaacgtctc ttatcctcat
     1681 gataatgctc tggacagagg caggctccat atttgaaaga aaagtcaaaa gcctgaccaa
     1741 cccgatggca gaagacacac tcattaaaat tgaggctgat tccaaatcga gtcaaaattt
     1801 gaatttcaaa aatattggtc aaaacctgat aatccaagcc tgcttccatc aactccaaag
     1861 tcttttgcaa aaaagcaaac aagggagcat cctgctgatt gtcctgcaaa ctagcatctg
     1921 caagagctgc cacataggtc gcataggcca tgacaaagag gtcactatta atcttgggaa
     1981 aagtcatgac ctcatgatag tcttcgatgt aactgagtcc gtcatcattg attcgcaaga
     2041 gaaatcgtgc cagcaccaag ggctgaataa caggcgccag cttagactga ccagcgtgtt
     2101 tgacaaaaaa catgcgtttg ccaacctgct ctgtaaaaat tttgacgagc ttgtcatcct
     2161 cacgaaaatt gcgattgtaa agcaccaagc cttgactcgt gatagactga atcatgcttc
     2221 tctcatgtac tcctcaagtc gtttcatggc ttctttgata gtctccatgc tggctgcata
     2281 agataggcgg acgtagcctt ccccgtaacg tccaaaggct gcaccaggga taaaggcaac
     2341 ggccttcttc tgagcaaaat ccttcagaaa agcaaaggag tcttgattgt agcccgctgg
     2401 aattttagca aaaatataga aggcaccgtc tggtttgata atctcaaaac caagagcagt
     2461 cattttttcg atgatatagt cccgacgttg gatatattcc ttcttcatgg gctccgcatc
     2521 gtttttacca gccgtcaagg cttctaccgc agcatgttgc gccatggtat ttgcggcagt
     2581 gaccaagtac tggtgactct tgattaactg ggctgtgaag gtcgcaggag cgaaaatcag
     2641 ccccaaacgc caacctgtca tggcatgcga tttagacaaa ccattgataa taatagcctg
     2701 gtctctcaac atcgttccta gagacacatg ggcttcgcct gtgtaggtca attctgagta
     2761 aacctcatca cagacaacaa aaacttcgta cttgcgtaaa acagctgcca aggcctctaa
     2821 ctgctctcga ctgtaggtaa ttcctgtcgg attggctgga tagttgagaa taaccgcctt
     2881 gagcttatca ccctgctcca aaatggcctt ctccaacatc tcaggagtca agacaaaacc
     2941 attttcagtc gtatcaatct caacaatttc tgccccaact aagttaacaa tcggttcata
     3001 gcctggataa gcaggagctg gcaaaagtac cttgtctccc tcttccaaaa tagccgtcaa
     3061 agtcgcagat aaagcctctg tcgccccaat tgtaaccaag atttcatttt caggagcata
     3121 gtccagttgg tacttttcct taacaaaatc actggccgcc tgacgtagag tcagcagacc
     3181 actcatccct gtatagtagg attggttctg atcaatcgct cgcttggccg cctccttgac
     3241 atggtctggc gttgtaaaat caggttcccc taaggtcaaa cgcaagaccc caggaatctc
     3301 cgaaatagcc tggtcaaact gacgaatcaa cgaaacttga attttatcta actgtttatt
     3361 aaagcgctta gttaagtcca tagatacctc ctactttcaa aacatatctc tattatacta
     3421 caaaagcccc ccgaccgcaa aaatacatta gagaatagct ttccactttc tattttactt
     3481 ttcctgttta caggtctata atggtaacag attctatttg gaggttttta tgtcatttct
     3541 atcaaaaaat ggagcaggca tcttggtctg ccttctcatt tctatcgtat cttggtactt
     3601 aggaggattc ttccctgtga ttggcgcgcc cgtttttgcg atttttatgg gcatgctcct
     3661 acatcccttt ctctcgtctt ataaacaact ggatgttgga ttgaccttta gttccaagaa
     3721 attgctccag tatgccgtta tcttgcttgg ttttggtctc aatatctctc aagtcttcgc
     3781 agttgggcaa tcttcactcc ctgtcatcct ttccaccatt tcaatagcct tgattgttgc
     3841 ctacctcttc cagcgcttct ttgccctgga tacaaaactg gctaccttga ttggagtagg
     3901 ttcttctatc tgtgggggtt ctgccattgc agcgacagcg cctgttatcc atgctaagga
     3961 aaaggaagta gcccaagcca tctccgttat ctttttcttc aatgtcttgg ctgcgctcat
     4021 ctttccaacc ctcggcacct ggcttcatct atccagtgac ggcttcgccc tctttgcagg
     4081 aactgcggtc aatgatactt cctctgtaac cgccacagct agcgcttggg acagtctcta
     4141 ccagaccaat accctcgaat ccgcaaccat tgtcaaactc acgcgaaccc tagctatcat
     4201 ccccatcact ctctttctct cctactggca aagtcgcgag caaaaaaata agcaaggctt
     4261 acaactgaaa aaagtcttcc cactttttat ccttcacttc atccttgcat cgctcctaac
     4321 cacccttctg acctctctcg gtgtgtctag tagtttcttt acccctctca aacaactctc
     4381 taaattcctc attatcatgg ccatgagtgc catcggtctc aaaactaatc tggtcgctat
     4441 ggtcaaatcc agtggaaaat ccattgttct cggagccgtc tgctggattg ccatcatcct
     4501 caccagcctt ggtatgcaga cccttatcgg cattttctaa tactcttcga aaatctcttc
     4561 aaaccacgtc aacgtcgcct tgccgtaggt atatgttact gacttcgtca gttctatctg
     4621 caacctcaaa acggtgtttt gagctgactt cgtcagttct atctgcaacc tcaaaacggt
     4681 gttttgagct gacttcgtca gttctatcta caacctcaaa acagtgtttt gagcagcccg
     4741 cggctagttt cctagtttgc tctttgattt tcattgagta taacacaaaa ggtagcccat
     4801 cagctacctt tttcttatgc ttcctcaatc aagcgagtat gttctctctt gatacagcga
     4861 ttcatcacga tatcatcaca tccaccatca cgcaaaatct ctttcgcttc taaactttca
     4921 agtcctagct gtgcccaaaa aatcttggca tcagctttga gaaaatcacg cgccacatcg
     4981 ggcagaaatt cactgcgacg ataaacattg acaatatcta caggaaaagg aatttcagcg
     5041 aggctagcat aagccttttc acccaagatt tcgccacctg ccgccttggg attgactggg
     5101 atgattttat agccccgagc ctgcatttcc tttgtcactc gattgctggt tgtttcttca
     5161 cggtcagaca aacccaccac agcaagggtt ttactcgttg cgagatactg acgaatcacg
     5221 ccatcacttg gattgataaa ttcttgactc atagaaatcc tcctttttca tcagtatagc
     5281 acattttgaa aaggtttgca gaattctact acaaaaaagg aggactagcc ccctttttat
     5341 ttagcctcgt accaggttgc tccttcattc tcatctgcga taagaggaac actgagttga
     5401 atggcttctt ccatggtttg tttcaccaat tttttcatct ctaccaattc agatttaggc
     5461 acttcaagga cgatttcatc gtgcacttgt aacagcatct tagtctgata accacctgca
     5521 accaaggctt tatccagctg aatcatggca atcttgagaa tatctgctgc cgaaccctgg
     5581 ataggtgagt tgatagcagt tcgctccgca aaaccacgaa tattgaagtt gcgcgaattg
     5641 atatctggca actcacggcg acgcttaaag agggtctcta catagccctt atcacgcgcc
     5701 tcccgcacca cttcatccat gtagttttta atacctggaa aacgttcaaa gtaggtatca
     5761 atgtaggctt tggcttcctt acgactaatt cccaaattat tagacaagcc aaagtctgaa
     5821 atcccataaa ccactccaaa gttaactgcc ttggcattac gacggtcatt tgcagtcaca
     5881 ttatcaggac gctcaatgcc aaagacccgc atggctgtcg aagtatggat atctgccccc
     5941 tcttggaagg ccttaatcaa gtgctcatcc ttagaaatat gcgccaaaac gcgcaattca
     6001 atctgtgaat agtcagagct gagtagcaca ctatcctccc actctggcac aaaagccttc
     6061 cgaatcaagc gcccctgttc caatcgggca ggaatatttt gcaagtttgg atccacacta
     6121 gacaaacgcc cggtctgggt caaatcctgc aaatagcgag tatgaatctt tccatcagcc
     6181 aaaatccagt cctgcaagcc aattacataa gtagattgaa tcttagcaat ttgacggtaa
     6241 tccaggattt tcttaacaat cggagcaata ggagcgagac gctccaaaac atccactgct
     6301 gtcgaataac ctgtcttggt tttcttagtg tattctagag gaagtcccaa tttctcaaag
     6361 agaagcacgc ccaactgctt aggcgagttg acattaaact cctcaccagc cagctcgtaa
     6421 atctcttgag acagtttttc aatgacaagc tcattttcag cctgcatctc aagcaaggtc
     6481 tctttcttaa ccataattcc agcaatttcc atcttggcaa ggacaaaagc cagaggttgc
     6541 tccatatcat aaagaagctc taattgccca ttttcgctga gtttttcaag taaaataggc
     6601 tctgtttcta ccaaaacagc aagtttacaa gctaagtgtt ccaagaattt ctcacgttca
     6661 ggaatggcct ttttaacacc cttaccgtag aaagtttcat catcaaccaa gtaagtctga
     6721 ccataaagac tagcgatggt cgcaatttca ttgtcctcca cagtcgaaag gaggtattta
     6781 gccaaacgga tgtcaaaagc aggcgcctgc aaatctacac caaaacgttg caaaagaact
     6841 ttaaccttct taaagtcata aactctcaga gatgtttttt ctaagaaatc cttgaaaatc
     6901 gggtcttgca acagctcaag cttgtctgtg gcatagagct gatccccaca agaccaggca
     6961 aatccaacca aattatctgt atggtaattc tcaccaaaaa gctcaaagtg gaagatagac
     7021 tcttcactca gcatatcttg actgatttgg tcaacaatag taaaatccaa accctcagcc
     7081 acatcagctg acgacatatt taaagcctgc ttgagctgtt tgaatcccat ctcatcgtaa
     7141 aatttcccaa gattttcaac atctggacca ctatagacca agtcctctaa accaatcgca
     7201 atcggtgcct tggtatcaat ggtcgctagt gttttagaca aaaaggcctg ttccttgtca
     7261 ttgatgagat tttccttcat cttagaagtc ttcattccat caatattttc ataaatcccc
     7321 tcaagcgaac catgctccag caagagctta atacccgtct tttcaccgac tttggtcacc
     7381 ccagggatat tatccgactt atcacccatg agcgccttga gatcgataaa ctgagctggt
     7441 gtgaggccca tttcttccat gaggtaatct ggcgtaaagg cctcaaactc agccacacct
     7501 ttcttggaaa tttcaaccac cgtatgctca tccgtcagct gaatcaaatc cttgtcccca
     7561 ctgacaatgg taatatcaaa accatcctgc tctgctagct tatccagcgt cccaatgatg
     7621 tcatccgcct catactgagc gagctcatag tgacgaatcc ccatatgatc cagcaactca
     7681 cgaatgaaag gaaattgctc acgaaactca tcaggagtct tggcccgacc acccttatag
     7741 tccgcataca tctctgtccg gaaggtcgtc tttcccgcat caaaagccac caaaatatga
     7801 ctcggctcaa cccgctccaa caaatgactc aacatcaact gaaaaccata aatcgcattg
     7861 gtatgcaaac cagccgcatt cttaaaacgg tccaactgct gatacagcgc aaaaaacgcc
     7921 cgaaaagcta cagaagaccc atcaatcaat aataattttt tcttatccat acacccatta
     7981 taaaggaaag aatcaaaaaa taccattggg aagagctaga gcaagtattt ttcaaacttt
     8041 ttccgaacaa atagatagag ccagagaatc tagtaaacct agatttaaaa atgtgctata
     8101 atatagtata ttgaatctat aatagtacac cttgactgct aaaatatttc tataaattaa
     8161 tttgactttc ctgatagagt tgtttcacat cttatttcaa ctcactatag aaggaggaaa
     8221 aggagggctg ggtggctaac ttcattatag aactttcaaa aagatgaaaa aatagcgtca
     8281 aagaggcttt tttctcttta aaacaggaaa tttcaaagac aatcttgcga ctatccaaac
     8341 tgtacgaata gcgagacata acttacttcg ctaatactat agtagattga aactagaata
     8401 gtacacctcg atttctaaaa cattgttaga aatcgatttg actgtcctga acgatttgtc
     8461 ctgttattat ttcattttac tatatcttat aaaaagatag aaatgtcaag caaaaatgac
     8521 aagtattttg ataataaact tgccatccca tcaactttct actatataaa gtatgaactc
     8581 atagcaagga ctcaaactca gccacggtca tgcctaattg ctcactcgca acctcaggtg
     8641 ttagaagacc ttgacgtact agatttacta aacctacttt taatccctct tcaaggcctt
     8701 cttctcgtcc ttgttcacaa ccctctgcac gaccac
//
LOCUS       DAVHTH010000069         8207 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.069, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000069 DAVHTH010000000
VERSION     DAVHTH010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8207)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8207)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8207
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.069"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            complement(120..350)
                     /locus_tag="VVR63_001842"
     CDS             complement(120..350)
                     /locus_tag="VVR63_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000832182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6129821.1"
                     /translation="MKRVILLAVIQAVVLFFIIGALAYAFKGDFFYNYLAVVFAPIAG
                     VLRFGTAYITEIVLPRKAAEIAEKRKAGKNSK"
     gene            complement(368..1009)
                     /locus_tag="VVR63_001843"
     CDS             complement(368..1009)
                     /locus_tag="VVR63_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU6129822.1"
                     /translation="MKLLKNLGWILLALLSFLFIYGFIQGLATASLALGASPYAVTLL
                     YVAFAGVYVYGIYKWYQKAPVHIEKSGFNRFIWLPVLVWFLSLVVQFFLPDDPSVNQQ
                     IATDLTLSQPLFSFFAVVIFAPLTEEIVFRGMLARYLFPKQDNSKRTLIFLLVSSLLF
                     ALIHFPGDVQQFFVYFSLGFSLGLAYISRKGLVYSISLHALNNLVGFLMILML"
     gene            complement(1021..1743)
                     /locus_tag="VVR63_001844"
     CDS             complement(1021..1743)
                     /locus_tag="VVR63_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HEU6129823.1"
                     /translation="MKKKRRLLFLMSIVLGMFVGMFKARVESHEIILDVKALMPWISA
                     ICLLIGFISMFLTFNFLKKSRKFHSLYQEEMDDDLNETYYVQMYRNLEFGTIAFNITG
                     VAIPLAIFISLSEVIILHTNPQTFFLSFLLFVVFLVAQKSLFKTIAIVRQFDLEFFAT
                     PKDVLNYINSYDEGERQANLEQSFRILFQLHQYVLPALYIFLIIISFLTGEIQLLAFL
                     LVGAIHVYINVMQLPMVKRYFK"
     gene            complement(1746..1943)
                     /locus_tag="VVR63_001845"
     CDS             complement(1746..1943)
                     /locus_tag="VVR63_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001046145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6129824.1"
                     /translation="MNKYKVIYYVVVIALLVSVFLLIGMDLSWFNLYQSDQFVWVYFA
                     LIPVIEWIEKKSKNLASEKGE"
     gene            complement(1943..2149)
                     /locus_tag="VVR63_001846"
     CDS             complement(1943..2149)
                     /locus_tag="VVR63_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU6129825.1"
                     /translation="MQLKNRLKELRARDGLNQTDLAKLAGVSRQTISLLERDEYTPSI
                     IIALKISQIFNETVESVFRLEEDE"
     gene            complement(2159..2473)
                     /locus_tag="VVR63_001847"
     CDS             complement(2159..2473)
                     /locus_tag="VVR63_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6129826.1"
                     /translation="MWVLGFILFMIFFYSNNSKKIKKLENKIKKLERKEKGNAEMSRL
                     FQEMIGKEPIITGVYIGPDNWEVVDVDEEWVKLRRVDNTGKEKFKLQRIEDIQTVEFD
                     GE"
     gene            complement(2737..2814)
                     /locus_tag="VVR63_001848"
                     /pseudo
     CDS             complement(2737..2814)
                     /locus_tag="VVR63_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(2811..4100)
                     /locus_tag="VVR63_001849"
     CDS             complement(2811..4100)
                     /locus_tag="VVR63_001849"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HEU6129827.1"
                     /translation="MKLQKPKGTQDILPAESAKWQYVEGFAREIFKRYNYAEVRTPIF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PSKFYYMGPMFRYERPQAGRLRQFHQIGVECFGSSNPATDVETIAMAAHFLKEIGIQG
                     VKLHLNTLGNPESRAAYRQALIDYLTPLKETLSKDSQRRLEENPLRVLDSKEKEDKVA
                     VENAPSILDFLDEESQTHFDAVRQMLENLGVDYIIDTNMVRGLDYYNHTIFEFITEIE
                     GNDLTVCAGGRYDGLVAYFGGPETAGFGFGLGVERLLLILEKQGVALPIENALDVYIA
                     VLGDGANVKALELVQALRQQGFKAERDYLNRKLKAQFKSADVFAAKTLITLGESEVES
                     GQVTVKNNQTREEVQVSLETISQNFSEIFEKLGFYTQ"
     gene            complement(4178..5425)
                     /locus_tag="VVR63_001850"
     CDS             complement(4178..5425)
                     /locus_tag="VVR63_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HEU6129828.1"
                     /translation="MKLLFRNPAYRILTLSRFFNAFGASIFNLVFIVYASTLSQASFA
                     VAMANIVMILPTLFTVFVGIRADYTRDKVKWMVYSGLFQAVLFFLAALVVQQASLFAF
                     SSLCLINVISDIISDFAGGLRMPLIKEKVAEDDLMEAYSFSQFITYISAIGGQAFGVW
                     LLALSVNNFSLVAGINACFFLVSATILFLGKSKLSLSMSSADGENLKNDKLSIKDQFL
                     TIYRNLRLVFLKSGQKNFGFMLFAVLLINSLGGALGGIYNIFFLSHSLLNFSYTEALF
                     INQFCVLVAIIISSLTGNDYFGKQSLPRLMMWATVGLSLVGLANLFNQVVLGLLFLFF
                     TLYVSGKVQPKISAMLMKNLAPEVLAHTSNFLGLLFTLSIPVGTACFSLVAVWNIQLT
                     WMLFVGLSLLAIFLTILNLKNDI"
     gene            5642..6988
                     /locus_tag="VVR63_001851"
     CDS             5642..6988
                     /locus_tag="VVR63_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element ISSpn5 family transposase"
                     /protein_id="HEU6129829.1"
                     /translation="MNSLPNHHFQNKSFYQLSFDGGHLTQYGGLIFFQELFSQLKLKE
                     RISKYLVTNDQRRYCRYSDSDILVQFLFQLLTGYGTDYACKELSADAYFPKLLEGGQL
                     ASQPTLSRFLSRTDEETVHSLRCLNLELVEFFLQFHQLNQLIVDIDSTHFTTYGKQEG
                     VAYNAHYRAHGYHPLYAFEGKTGYCFNAQLRPGNRYCSEEADSFITPVLERFNQLLFR
                     MDSGFATPKLYDLIEKTGQYYLIKLKKNTVLSRLGDLSLPCPQDEDLTILPHSAYSET
                     LYQAGSWSHKRRVCQFSERKEGNLFYDVISLVTNMTSGTSQDQFQLYRGRGQAENFIK
                     EMKEGFFGDKTDSSTLIKNEVRMMMSCIAYNLYLFLKHLAGGDFQTLTIKRFRHLFLH
                     VVGKCVRTGRKQLLKLSSLYAYSELFSALYSRIRKVNLNLPVPYEPPRRKASLMMH"
     gene            complement(7324..8175)
                     /gene="rgg"
                     /locus_tag="VVR63_001852"
     CDS             complement(7324..8175)
                     /gene="rgg"
                     /locus_tag="VVR63_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434947.1"
                     /note="Rgg, as the term is used in Streptococcus
                     pneumoniae, is the lone quorum-sensing system
                     transcriptional regulator related to proteins Rgg1, Rgg2,
                     Rgg3, and Rgg4 of Streptococcus pyogenes; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg"
                     /protein_id="HEU6129830.1"
                     /translation="MEQIGKVFRQLRESRNISLRQATGGQFSPSMLSRFETGQSELSV
                     EKFLFALENISASVEEILFLARGFQYDTDSELRKEITDVLEPKNVAPLEDLYRREYQK
                     HAHSHNKQKHILNAIMIKSYMKSMDERVELTAEEGKVLHDYLFSTEIWGIYELNLFSV
                     SSPFLSVSLFTRYVREMVRKSDFLMEMSGNRNLFYTILLNGFLASIECEEFTNAYYFK
                     RVIEEHFYKENETYFRIVYLWAEGLLDSKQGRVKEGQKKMEDAVRIFEMLGCNKSAEY
                     YRNTTEC"
BASE COUNT         2592 a         1741 c         1513 g         2361 t
ORIGIN      
        1 gtcagtttca tccacaacct caaaacagtg ttttgagcaa cctgcggcta gcttcctagt
       61 ttgctctttg attttcattg agtataatac aaaaatccga tgaacttcac cggactcttt
      121 tattttgaat ttttgcctgc tttacgcttt tcagcgattt cggctgcctt tcgaggcaag
      181 acaatttccg ttatgtaagc cgtcccaaaa cgcagtacac ctgcaatagg agcaaagaca
      241 actgctagat agttatagaa gaaatcgcct ttgaaggcat aagctagcgc tccaatgatg
      301 aaaaatagaa cgactgcctg aatcactgct aataaaatta ctcgtttcat gtgacctcct
      361 gactctatta tagcatgaga atcatcaaaa agccgactaa attattcaaa gcgtgaagag
      421 aaatactgta gaccagacct tttctgctaa tgtaagccaa acccaaacta aaaccaaggc
      481 taaaatagac aaaaaattgt tgcacatcac ctggaaaatg aatcaaggca aatagaagac
      541 tagataccag aagaaaaatc agggttcgtt tactattgtc ctgcttagga aagagatagc
      601 gtgctaacat ccctctaaaa acaatctctt ccgtcaaagg agcaaaaata accacagcaa
      661 agaatgagaa aagtggttga gacaaggtca agtctgtcgc tatttgctga tttactgaag
      721 gatcatctgg caagaagaat tgaacgacca gagataagaa ccaaaccaag acaggaagcc
      781 aaataaatcg attaaagccg ctcttctcaa tatgaacagg agccttctga taccatttgt
      841 aaatgccgta cacatatact ccagcaaagg ccacatagag tagagtaaca gcatagggtg
      901 aagcgcctaa agcaagcgac gcagtcgcga gcccctgaat aaagccatag ataaataaaa
      961 aggatagaag ggctagaaga atccagccaa ggtttttaag taatttcata gataactcct
     1021 ttatttgaaa taacgtttta ccataggtaa ctgcatcaca ttgatataaa catggatggc
     1081 tcctacaagc aagaaagcta gtaactgaat ctctcctgtc aagaaagaaa tgataataag
     1141 aaaaatatat aaggctggta agacatattg gtgtaattgg aataaaattc gaaaactctg
     1201 ttccaaatta gcctgacgct ccccttcatc ataagaattt atatagttca agacatcctt
     1261 tggtgtagcg aaaaattcca aatcaaactg acgaacaatc gcaatggttt taaaaagaga
     1321 tttttgagcg actaagaata ccacaaagag taagaaagaa aggaaaaatg tttgagggtt
     1381 tgtatgcaat ataatcacct cacttaatga aataaaaata gccaatggaa tcgctacacc
     1441 tgtaatatta aaagcaatgg ttccaaactc aagattccga tacatttgca cataataggt
     1501 ttcattcaga tcgtcatcca tttcctcttg atacaaggaa tgaaattttc tgcttttctt
     1561 taagaaattg aaagtcaaaa acatactaat gaaacctatc agtaaacaaa tagctgatat
     1621 ccatggcatc aaggctttta catctaaaat aatttcgtgg gattcgacac gtgccttaaa
     1681 catccctaca aacatgccca agacaataga catcaaaaat aacaatctac gtttcttttt
     1741 catattcatt ctcctttttc acttgctaga tttttggatt tcttttcaat ccattcaatt
     1801 actgggatga gagcaaagta gacccaaaca aattggtcgc tttgatagag attaaaccag
     1861 cttaggtcca tcccaatcag tagaaataca ctgactaata aagctatgac cactacataa
     1921 taaatcactt tatacttgtt catcactcgt cctcctccaa acgaaatacc gattcgactg
     1981 tttcgttgaa aatttgagat attttcaggg caatgataat ggatggggtg tactcatccc
     2041 gttctagtag gctaatggtc tgtctggaaa cccctgccag tttggctagg tcggtttgat
     2101 tgagaccatc gcgagctcta agctctttta gacgattttt aagttgcatg ttacacacct
     2161 actctccgtc aaattcaacg gtttggatat cctcaatgcg ttgcaacttg aatttttctt
     2221 ttcccgtatt atctacacgt cgtagcttta cccattcctc atcaacatcc acaacttccc
     2281 agttatctgg cccaatatac actcccgtta taattggttc ctttccaatc atttcttgaa
     2341 ataatctcga catttctgcg tttcctttct cttttcgctc aagttttttg attttattct
     2401 ctagtttctt gattttttta gaattattag aataaaagaa aatcataaat agtataaatc
     2461 ctagtaccca catcatagct cctttcttct tttctcttaa cttgcttaca tcgtaacaca
     2521 tctttttctt tttgacaagt atagttgtca aaaagtttat gatttttgtc attttgcaaa
     2581 ggaaaaaggt caggagtaag ttcctgacca ctttatctat cattaatact cttcgaaaat
     2641 ctcttcaaac cacgtcagct tcacctcgcc gtaggtatgg ttactgactt cgtcagtttc
     2701 atctacaacc tcaaaaccat gttttgagct gacttcgtca gttctatcca taacttcaaa
     2761 acagtgtttt gagcaacctg cggctagctt cctagtttgc tctttgattt tcattgagta
     2821 taaaatccta gtttttcaaa gatttctgag aagttttggc tgattgtctc aagtgacact
     2881 tgcacttctt ctcgggtttg gttgttcttg accgtcactt gtccgctttc gacttcgctc
     2941 tctcctaggg tgatgagggt cttagccgca aagacatctg ctgacttgaa ctgagctttg
     3001 agcttacggt tgaggtaatc acgctctgct ttgaaacctt gttggcgaag agcttggact
     3061 agttctaggg ctttgacatt tgctccatca cccaagactg cgatatagac atctagggcg
     3121 ttttcgatag ggagggccac gccttgtttt tcaaggatga gaagcaggcg ctctacacca
     3181 agcccaaaac caaatccagc agtttcaggg cctccaaagt aagcaaccaa accatcgtag
     3241 cgaccacccg cacagactgt caagtcattg ccctcaatct ctgtgataaa ctcgaaaatg
     3301 gtgtggttgt agtagtccag accacgcacc atattggtat cgatgatgta atctactcca
     3361 agattttcca acatctgacg cacagcatca aaatgagttt ggctttcttc atcaagaaag
     3421 tccaagatag acggcgcatt ctctactgcc accttgtctt ctttttcctt agagtccaag
     3481 acacgaagag gattttcctc caagcgacgt tggctatcct tagacaaggt ctccttgagc
     3541 ggtgtcaaat agtcaatcaa ggcttggcgg taggctgcac ggctctcagg atttccaaga
     3601 gtgttgaggt gcaatttgac accttgaata ccgatttcct tcaaaaaatg ggctgccata
     3661 gcgattgttt ccacatcggt agctggattg ctagagccaa aacactcaac accaatctgg
     3721 tggaattggc gcaagcgccc tgcctgtgga cgctcataac ggaacatagg tcccatgtag
     3781 tagaacttgc ttggcttttg cacttctggg gcgaagagtt tattttccac ataggaacgg
     3841 acaacgggcg cagttccttc tggacggagg gtaatatggc ggtcaccctt gtcatagaaa
     3901 tcgtacattt ccttggttac gatatcggtc gtatctccga cagagcggct gataacctcg
     3961 taatgctcaa aaatgggcgt gcgcacttct gcgtagttgt agcgcttgaa aatttcacgg
     4021 gcaaagccct caacgtactg ccatttggca gattcagcag gtaaaatatc ctgcgttcct
     4081 tttggttttt gtaatttcat agggaatcct ctttaaactt aatagtctta ttttaccaca
     4141 aataaaggga ttaaaacagt gagaaaaaaa ttaggattta gatatcattt ttgagattaa
     4201 gaattgtcaa aaaaatagct agcaaggaaa gaccaacaaa tagcatccaa gtcaactgta
     4261 tattccatac ggctactagt gaaaaacaag ctgttcccac aggtatggat aaggtaaaca
     4321 atagacctaa aaaattacta gtatgagcta gaacctctgg agctagattt ttcatgagca
     4381 tggcactaat ctttggttga actttaccag acacatacag agtaaagaag agaaatagca
     4441 aaccaagcac gacttgattg aataaattag ccaaaccaac tagactaagt cctacggtcg
     4501 cccacatcat caatctaggc aaggactgct tcccaaaata atcattgccc gtaaggctac
     4561 tgatgatgat tgctactaaa acacagaatt gattgataaa tagtgcctct gtataagaaa
     4621 aattcaagag agaatggctc aaaaagaaga tattataaat tccacccaaa gcgccaccca
     4681 aggaattaat aagcaagaca gcaaagagca taaaaccaaa gtttttctgt ccacttttaa
     4741 gaaaaacgag acgtaaattt cggtaaattg ttaggaactg gtctttgata gaaagcttat
     4801 cattttttaa gttttcacca tcagcagatg acattgacag gctcaatttg ctttttccta
     4861 aaaagaggat agtggctgat actaggaaaa agcaggcatt gattcccgca acgagagaaa
     4921 aattgttgac cgatagagct aagagccaga ctccgaaagc ttgaccacca atagctgaaa
     4981 tataggtgat gaactgtgaa aaagaataag cctccatcaa atcatcttca gctacttttt
     5041 ccttaataag aggcatacgc aggccacctg caaaatcact gatgatatca ctaatgacat
     5101 tgatcaaaca caggctagaa aaggcaaaga gactagcttg ctgaacaact agggctgcta
     5161 gaaaaaatag aaccgcctga aacaaaccgc tatagaccat ccatttgacc ttgtccctcg
     5221 tgtaatctgc ccgaatccct acaaaaactg taaagagggt cggaagaatc atgacaatat
     5281 tcgccatagc aacagcaaaa gatgcttgtg acaaggtcga tgcatagacg ataaagacca
     5341 ggttgaaaat cgaagcacca aaagcattga agaagcgtga taaagtcaaa attctataag
     5401 ctggatttct aaacaatagt ttcatagata atctccctcc ttgttctaag ttctacatca
     5461 agaatagctt tagtatcccc aattattcac cccaaatcta aaaaccatcc agaatccttg
     5521 ccttagctta gatcctggat ggtttctttt ttcacccaat gggtgttttt tactagacaa
     5581 aaaagagttt cccctttatg gtataagtgt agaaaaaaac acaaaaagaa aggaaactca
     5641 catgaacagt ttaccaaatc atcacttcca aaacaagtct ttttaccaac tatctttcga
     5701 tggaggtcat ttaacccagt atggtggtct tatctttttt caggaacttt tttcccagct
     5761 gaaactaaaa gagcggattt ctaagtattt agtaacgaat gaccaacgcc gctactgtcg
     5821 ttattcggat tcagatatcc ttgtccagtt cctctttcaa ctgttaacag gttatggaac
     5881 ggactatgct tgtaaagaat tgtcagctga tgcctacttt ccaaaattat tggaaggagg
     5941 gcagcttgct tcacagccaa ccttatcccg ttttctttcc agaactgacg aggaaacagt
     6001 ccatagtttg cgatgcctca accttgaatt ggtcgaattc tttttacagt ttcaccagct
     6061 aaaccaactc attgtagata tcgattctac ccatttcaca acttatggca agcaagaagg
     6121 tgttgcttat aacgcccact atcgtgctca tggctatcat cctctttatg ctttcgaggg
     6181 gaagacaggt tattgtttca atgcccagct tcgtcctggt aatcgttatt gttctgaaga
     6241 ggcagacagc tttatcacac ctgttttaga acggtttaat caacttctct ttcgaatgga
     6301 tagtggcttt gcgaccccaa aattatacga tttaattgaa aaaacagggc aatactacct
     6361 cataaaactc aagaaaaata ctgttctgag ccgtcttgga gacctttccc tcccttgccc
     6421 acaggatgag gacttaacca tcttgcccca ctccgcctac tcagaaactc tctatcaagc
     6481 aggatcttgg tcgcacaagc gtcgtgtctg ccagttctct gaacgaaaag aaggaaactt
     6541 gttctacgat gttatttctc tcgttacaaa tatgacgagt ggaacaagcc aagatcagtt
     6601 tcagctttat cgtggacgtg gtcaagccga gaatttcatc aaggagatga aggagggatt
     6661 ttttggcgat aaaacggata gttcaacctt aatcaaaaac gaagttcgta tgatgatgag
     6721 ctgtatcgcc tacaatctct atctttttct caaacatcta gctggaggtg acttccaaac
     6781 tttaacaatc aaacgcttcc gccatctttt tcttcacgtg gtaggaaaat gtgttcgaac
     6841 aggacgcaag cagctcctca aattgtctag tctctatgcc tattccgaat tgttttcagc
     6901 actttattct aggattagaa aagtcaacct gaatcttcct gttccttatg aaccacctag
     6961 aagaaaagcg tcgttaatga tgcattaaag aacagtcgag atgaaaaaat cgtgtgacga
     7021 accaagggag gagtctgccc ttttgaggaa atctagcgag gaaaaacgat actggaacag
     7081 cagaaagtaa aactgacctc atgaggagga agaaagtggc tcatgaggtc aggggttttg
     7141 taagttacat ctagttgaga gaggtatgaa tgatttggga gtatagcact tatgaatttg
     7201 cgaaacgatt cttttgaata tatgcaacaa acaaaatgag caaaaaaacg atagaacttt
     7261 tgtaatgacc tgagagaggg caacagttct atcgcttcaa attttttctt ggtttgcaga
     7321 tactcaacat tcggtcgtat ttctatagta ttcggcagat ttattacagc caagcatctc
     7381 aaaaatacgg acagcatcct ccatcttttt ctgaccttcc ttgactctac cttgcttgct
     7441 atcaaggaga ccttctgccc acagataaac aattcggaaa taggtctcat tttccttgta
     7501 gaaatgctct tcgataacac gtttaaaata ataggcattg gtaaattctt cacactcaat
     7561 actagctaaa aagccattca atagtatagt ataaaaaagg tttcgattgc cagacatttc
     7621 cattagaaaa tcggatttac gtaccatttc tcgtacatat ctagtaaaaa gagaaacaga
     7681 taaaaatgga gaactgactg aaaataaatt gagttcatag attccccaga tctcggtaga
     7741 aaacaaataa tcatgaagga cttttccttc ctctgctgtt aactctaccc tttcatccat
     7801 gctcttcata taagacttga tcataatggc atttagaata tgtttctgtt tgttgtgaga
     7861 atgggcatgc ttttgatact ccctgcgata taagtcctca agaggtgcta cattctttgg
     7921 ttccaagaca tctgtaattt cttttctcaa ctcagaatct gtatcatact ggaaacctct
     7981 cgccagaaag aggatctcct ccacactggc agatatattt tccagagcaa atagaaactt
     8041 ttccaccgaa agctcactct gacctgtttc aaaacgggac aacatagacg gcgaaaattg
     8101 tcctccggtt gcttgtctca gtgagatatt tcttgactct cgtaattgtc taaagacttt
     8161 tccaatctgc tccatagact tccccttgat tccgtatttt cttcatt
//
LOCUS       DAVHTH010000070         7984 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.070, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000070 DAVHTH010000000
VERSION     DAVHTH010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7984)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7984)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7984
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.070"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            443..1804
                     /gene="trpE"
                     /locus_tag="VVR63_001853"
     CDS             443..1804
                     /gene="trpE"
                     /locus_tag="VVR63_001853"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HEU6129831.1"
                     /translation="MERIIHGDVLSPILAYMRLKGQHKVILESIPRDKETARFSILAY
                     NPVFEIKFENGVLYQNGQVIDRDPLDLLYEVIHKSQHHSELPFGGGAIGFVGYDMISL
                     YEEIGQIPEDTIGTPDMHFFVYESYMVFDHKKEKIHVIEDALYSERSQEVLEKSLNQV
                     LEELRIPAPNEFEDLDLSPLDFKPHIAPHKFEGMVETARDLIRNGDMFQCVLSQRFSA
                     EVTGNPFDFYRNLRVINPSNYLYFYDFGDYQIIGASPESLVSVKNGIVTTNPIAGTRP
                     RGATDEEDKALATDLLSDEKETAEHRMLVDLGRNDIGRISETTSVQVTKYMEVELFRY
                     VMHLTSVVKGRLLAELTAMDALKATLPAGTVSGAPKIRAMRRIYELETEKRGVYAGAI
                     GYLSATGDMDLAIAIRTMILKNQRAYVQAGAGIVYDSIAQNEYQETINKAKSMTRIGE
                     LRP"
     gene            1801..2367
                     /locus_tag="VVR63_001854"
     CDS             1801..2367
                     /locus_tag="VVR63_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HEU6129832.1"
                     /translation="MILLIDNYDSFTYNLAQYIGNFAEVQVLRNDDSKLYEEAEKADG
                     LVFSPGPGWPVDAGKMEDMICDFAGKKPILGICLGHQAIAEVFGGKLGLAPKVMHGKQ
                     SNINFEAPSVLYQGIEDGHAVMRYHSILIEEMPEDFEVTARSTDDQAIMGIQHKNLPI
                     YGFQYHPESIGTPDGLSSIRNFIEKVVK"
     gene            2378..3382
                     /gene="trpD"
                     /locus_tag="VVR63_001855"
     CDS             2378..3382
                     /gene="trpD"
                     /locus_tag="VVR63_001855"
                     /EC_number="2.4.2.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="HEU6129833.1"
                     /translation="MKEIIEKLAKFENLSGVEMTDVIERIVTGRVTEAQIASLLLALK
                     MKGETPEERTAIAQVMRGHAQHIPTEIHDAMDNCGTGGDKSFSFNISTTAAFVLAGGG
                     IHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKY
                     IMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNMGRKRAIVVA
                     GPEGLDEAGLNGTTKIALLENGEISLSSFTPEDLGMEDYAMEDIRGGNAQENAEILLS
                     VLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARGKALEKLRLLQEYQK
                     "
     gene            3379..4146
                     /gene="trpC"
                     /locus_tag="VVR63_001856"
     CDS             3379..4146
                     /gene="trpC"
                     /locus_tag="VVR63_001856"
                     /EC_number="4.1.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011227478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indole-3-glycerol phosphate synthase TrpC"
                     /protein_id="HEU6129834.1"
                     /translation="MSQEFLARILEQKAREVEQMKLEQIQPLRQTYRLAEFLKNHQDR
                     LQVIAEVKKASPSLGDINLDVDIVQQAQTYEENGAVMISVLTDEVFFKGHLDYLREIS
                     SQVEIPTLNKDFIIDEKQIIRARNAGATVILLIVAALSEERLKELYDYATELGLEVLV
                     ETHNLAELEVAHRLGAEIIGVNNRNLTTFEVDLQTSVDLAPYFEEGRYYISESAIFTG
                     QDAERLAPYFNGILVGTALMQAENVAQRIKELQIDKG"
     gene            4133..4732
                     /locus_tag="VVR63_001857"
     CDS             4133..4732
                     /locus_tag="VVR63_001857"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HEU6129835.1"
                     /translation="MTKVKICGLSTKEAVETAVSAGADYIGFVFAPSKRQVTLEEAAE
                     LAKLIPADVKKVGVFVSPSRVELLEAIDKVGLDLVQVHGQVAADLFENLPCASIQAVQ
                     VDGNGHVPNSQADYLLFDAPVAGSGQSFDWGQLDTTGLAQPFFIAGGLNEDNVVKAIQ
                     HFTPYAVDVSSGVETDGQKNHEKIRRFIERVKHGISGTK"
     gene            4710..5933
                     /gene="trpB"
                     /locus_tag="VVR63_001858"
     CDS             4710..5933
                     /gene="trpB"
                     /locus_tag="VVR63_001858"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HEU6129836.1"
                     /translation="MAYQEPNKDGFYGKFGGRFVPETLMTAVLELEKAYRESQADPSF
                     QEELNQLLRQYVGRETPLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQVWLA
                     KRMGKKKIIAETGAGQHGVATATAAALFNMECTIYMGEEDVKRQALNVFRMELLGAKV
                     EAVTDGSRVLKDAVNAALRSWVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQ
                     QYRDMTGQNLPDALVACVGGGSNAIGLFHPFVEDESVAMYGTEAAGLGVDTEHHAATL
                     TKGRPGVLHGSLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSHYHDIKRASYVPVTD
                     EEALEGFQLLSRVEGIIPALESSHAIAFAVKLAKELGPEKSMIVCLSGRGDKDVVQVK
                     DRLEADAAKKGEAHA"
     gene            5926..6702
                     /locus_tag="VVR63_001859"
     CDS             5926..6702
                     /locus_tag="VVR63_001859"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HEU6129837.1"
                     /translation="MPKTLTEKLNAIKAAGKGIFVPYIMAGDHEKGLDGLAETIHFLE
                     DLGVSAIEVGIPFSDPVADGPVIEEAGLRSLAHGTSTQALVETLKTIETEIPLVIMTY
                     FNPLFQYGVENFVKDLADTAVKGLIIPDLPHEHANFVEPFLADTDIALIPLVSLTTGI
                     ERQKELIEGAEGFIYAVAINGVTGKSGNYRADLDKHLAQLHQVADIPVLTGFGVSSQA
                     DLERFNAVSDGVIVGSKIVKALHQGEPIQDFIKQAVAYQK"
     gene            complement(6674..6775)
                     /locus_tag="VVR63_001860"
                     /pseudo
     CDS             complement(6674..6775)
                     /locus_tag="VVR63_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564993.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
     gene            7004..7735
                     /locus_tag="VVR63_001861"
     CDS             7004..7735
                     /locus_tag="VVR63_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000934015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6129838.1"
                     /translation="MLNQDLFDSLEAQKIVDTLMKGQKDYVDERLEKRETMIVSNGYA
                     WTRPNHIDTAFASADLFEYKLQLAGQTWGYLEFETNTEKYGKVLLIIKGKKRLTNQFP
                     LVQKNKSGYLFEYAQMNTLYLNQHSSYKNDEDSHSFPIQMELVSDEMIQEIEQATKNS
                     NIEKFMILTYEADSENNIISVDVVMPDARTGQLHLIQDLSEYIQSSSYHFEEAKYQDI
                     PNFSELSETEDFEIIPRIEKQEGQK"
     gene            7750..>7984
                     /locus_tag="VVR63_001862"
     CDS             7750..>7984
                     /locus_tag="VVR63_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU6129839.1"
                     /translation="MFNGRVLKELRLLNGLSRAELAQRINLTEQAIWQFESNETKPKL
                     STKMHLANQFHVDLTYFEQEEESIRFDSSVIAFR"
BASE COUNT         2395 a         1509 c         1910 g         2170 t
ORIGIN      
        1 atacctacga taaggcgacg ttgactcggt ttgaagagtt tttcgaagag tataaaggtg
       61 taccgagatg aacatctctt catcaatgtc tctggtcgtg gaggcaagga cctagctgcg
      121 attgcagatt actagaagct aaaaaataat agatggaaaa attacagttc tttctctcac
      181 agagagcttg tggttgctga aaacaagcag agaaagctgt aaagttgggt tcatctgaaa
      241 cgagagaaga aaacatcatt ctcaagggag tgccctttat cgcacagcct gttacaggag
      301 gtatctgaga caggaatgag agataggaga aatcctataa ttgaggtggc accgcgaatt
      361 tcgtcctcac gcaagttatt ttgcgtgggg atttttcata cagtcgccac gaactagaat
      421 tagaactgaa agggaaatta caatggaacg aatcattcat ggagatgtct tatcaccaat
      481 cttggcttat atgcgcttaa aggggcaaca taaggttatt ttagagagta ttccgagaga
      541 caaggaaaca gctcgttttt ctatcctagc ctataatcca gtttttgaga ttaagtttga
      601 aaatggagtt ctctatcaaa atggtcaagt gattgatcgg gatcccttgg atctccttta
      661 tgaagtgatt cataagagtc agcaccactc agagctacct tttggtggtg gagccattgg
      721 ttttgtgggt tacgatatga tttcgcttta tgaagaaatt ggtcaaatcc ctgaggatac
      781 aattgggacg ccagacatgc atttctttgt ctatgagagc tatatggtct ttgaccacaa
      841 gaaggagaag atacatgtca tagaggatgc tctctatagt gagcgcagtc aagaggtctt
      901 ggaaaaatcc ttgaaccaag tgcttgagga attacgcatt cctgctccaa atgaatttga
      961 agacttggat ttatcaccac ttgacttcaa accgcatatc gctccacata agtttgaggg
     1021 aatggtagaa acagctcgtg acttgattcg taatggtgat atgttccaat gtgtactcag
     1081 ccagcgtttc tcagcagaag ttactggaaa tccatttgac ttctacagaa atctccgcgt
     1141 gattaatcca tccaattacc tctatttcta tgattttggg gattatcaaa tcatcggagc
     1201 cagtccagaa agtttggttt ctgtcaaaaa tggcatcgtg acaaccaatc cgattgcagg
     1261 gacgcgacca agaggggcta cggatgaaga agacaaggcc ttggcgactg acctcctctc
     1321 tgatgagaag gaaacagcag agcatcgaat gttagtagac ctgggtcgta atgatattgg
     1381 tcgcatctct gaaacgacca gtgtccaagt cactaagtat atggaagtgg agctcttccg
     1441 ttatgttatg catctgacca gcgtggtcaa ggggcgtttg cttgcagaac tcactgccat
     1501 ggatgccttg aaagctacac ttcctgctgg aaccgtttct ggagcaccaa agattcgagc
     1561 gatgagacgt atctatgaac tggaaacgga aaaacgggga gtatacgctg gggcaatcgg
     1621 ctacttgtct gcgacgggtg atatggattt ggccatcgcc atccgaacca tgattctcaa
     1681 aaatcaaaga gcctatgtgc aggctggggc agggattgtc tacgactcta tcgcccaaaa
     1741 cgaataccaa gaaaccatta acaaagcaaa atctatgact agaattggag aactaagacc
     1801 atgattttat tgattgacaa ctatgattct tttacctata acttggccca atacattggg
     1861 aattttgcag aagttcaggt tctgagaaat gatgattcca agctgtatga agaagctgaa
     1921 aaagcagatg gtctggtctt ttctcctggt cctggttggc cagttgatgc tggaaagatg
     1981 gaagacatga tttgtgattt tgcaggcaag aagccgattc tagggatttg tttgggtcac
     2041 caagccattg cagaagtctt tggtggtaag ctaggtttgg ctccaaaagt catgcatggg
     2101 aaacagagca atatcaactt tgaagcgcca tctgttttgt atcaaggtat tgaggatgga
     2161 catgcggtca tgcgttatca cagtattttg attgaggaaa tgccagaaga ctttgaagtg
     2221 acagctcgtt cgactgatga ccaagccatc atggggattc aacataaaaa cctaccgatt
     2281 tatggcttcc agtaccatcc agagagcatt ggaacgccag acggcttgtc ttctattcgg
     2341 aattttatcg agaaggttgt aaagtgagga aactaggatg aaagagatta ttgaaaaact
     2401 agcaaaattt gaaaatttat caggtgtgga aatgacggat gtcattgagc gtatcgtaac
     2461 tgggcgtgta actgaagcgc agattgcttc tctcctctta gctcttaaga tgaaggggga
     2521 aacacctgaa gaacgtacag ccattgccca agtcatgaga ggacatgccc agcatattcc
     2581 aactgagatt catgatgcta tggacaactg tggtacaggt ggggacaagt ctttcagttt
     2641 taatatttcc acaactgcag cctttgtctt ggctggtggc ggtattcaca tggccaagca
     2701 tggtaaccgc tcgatttctt ctaaatctgg ttccgcagat gtcctcgaag ccttgggaat
     2761 caatcttgac ctcaaaccag ctgaactagg taaggtcttt gataaaactg gaatcgtctt
     2821 tctcttcgct aaaaatatgc acccagctat gaaatacatc atgccagctc gtttggaatt
     2881 gggaattcca acgattatga acttgactgg tccactgatt catccaatgg ctttagaaac
     2941 acagcttctt ggaattagtc gtccagaact cctagaaagt acagctcagg ttttgaaaaa
     3001 tatgggtcgc aaacgtgcca tcgtggttgc tggaccagaa gggttggatg aagctggctt
     3061 gaacggaaca accaagattg cacttcttga aaatggcgaa atcagcttgt caagctttac
     3121 tccagaggat ttgggaatgg aagactatgc tatggaagat attcgtggtg ggaatgctca
     3181 ggaaaatgca gaaattttgc ttagcgttct gaaaaacgaa gcaagtccat tcttggaaac
     3241 gacagtcttg aatgctggtc ttggtttcta tgctaatggt aagattgata gcatcaagga
     3301 aggagttgcc ttggcccgtc aagtgattgc tagaggcaag gcccttgaaa aactcagact
     3361 gttacaggag taccaaaaat gagtcaggaa tttttagcac gaatcttaga gcagaaggcg
     3421 cgtgaggtgg agcagatgaa gctggagcaa atccagcctc tgcgccagac ctatcgcttg
     3481 gcagaatttt tgaagaatca tcaggaccgc ttgcaggtaa tcgctgaggt caagaaagct
     3541 agccctagtt tgggagatat caatctcgat gtggatattg tgcaacaggc ccagacttat
     3601 gaagaaaacg gagcagtgat gatttcggtg ttgacagatg aggttttctt taaagggcat
     3661 ttggattatc tacgggaaat ttccagtcag gtagagattc cgacgctcaa caaagacttt
     3721 atcatagatg aaaagcaaat catccgcgct cgcaatgcag gtgcgacagt tatcttgctt
     3781 attgtggcag ccttgtccga agaacgcctc aaggaactgt atgactacgc gacagagctt
     3841 ggtctggaag tcttagtgga gactcacaat ctagctgaac tagaggtagc ccacagactt
     3901 ggtgctgaga ttatcggggt caacaaccgc aacttgacta cctttgaggt cgacttgcag
     3961 accagtgtag atttagcccc ttactttgag gaaggtcgct attacatttc tgaatctgcc
     4021 attttcacag ggcaggatgc ggaacgacta gccccatact ttaacggaat tttggtaggg
     4081 acagctctta tgcaggcaga aaatgtggcc cagagaatca aggagttgca gattgacaaa
     4141 ggttaaaatt tgtggactat cgaccaaaga agcggtggaa acagccgttt cagcaggagc
     4201 cgactatatc ggttttgtct ttgcacctag taaaagacag gtgactttag aagaggcagc
     4261 tgagttggca aagcttattc ctgcagatgt gaaaaaggtt ggagtatttg tttcaccaag
     4321 tcgggtagaa ctgctggaag cgattgacaa agttggcttg gacttggttc aagttcacgg
     4381 tcaggtggca gctgatttat ttgagaattt gccttgtgcc agtattcagg ctgtgcaggt
     4441 agatggaaat gggcatgtcc ccaattctca ggcagattat ctactctttg atgcccctgt
     4501 ggcaggaagt ggtcagtcct ttgattgggg tcaactggat acgactggac tagcacagcc
     4561 cttctttatc gcaggtggcc ttaatgaaga taatgtagta aaagcaattc aacattttac
     4621 tccctatgca gtagatgtat cgagcggagt ggagacagat ggacaaaaaa atcatgaaaa
     4681 gattagaaga tttatagaga gggtaaagca tggcatatca ggaaccaaat aaagatggat
     4741 tttacggaaa attcggcgga cgttttgtcc cagaaacatt gatgacagca gttttggagt
     4801 tggagaaggc ctatcgtgaa agtcaggcag acccaagttt ccaagaggaa ttaaaccaac
     4861 tcttgcgcca gtatgtgggg cgggaaactc ctctttacta cgcaaaaaac ttgacccagc
     4921 atattggcgg agccaagatt tatctcaaac gggaagacct taaccataca ggagcccaca
     4981 agattaacaa tgccttagga caagtttggc ttgccaaacg catgggtaaa aagaaaatta
     5041 tcgcagaaac cggtgctggt cagcacggtg tggcaactgc aactgctgcg gccctcttta
     5101 acatggaatg taccatctac atgggtgagg aagatgtcaa acgccaagcc ctcaatgtct
     5161 tccgcatgga gcttttggga gccaaggtcg aggctgtaac agatggttcg cgcgtgctca
     5221 aggatgcggt caatgcagcc cttcgttcat gggtggctaa tatcgacgat acccactata
     5281 tccttggttc tgccttgggg cctcatccat ttccagaaat cgttcgtgac ttccaaagtg
     5341 tcatcggtcg cgaagctaaa caacagtatc gcgatatgac aggtcaaaat ctgcccgatg
     5401 ctctagtagc ctgtgttggt ggtggatcta atgctattgg gctcttccat ccctttgtag
     5461 aagatgagtc agtagctatg tatggaactg aagcagcagg gcttggtgtg gatacagagc
     5521 accacgctgc taccttgacc aagggtcgtc cgggtgttct tcacggttct ctcatggatg
     5581 tgctccaaga tgcccatggt caaattcttg aagccttctc tatctcagca ggtttggact
     5641 atcctggtat tggtccagaa cattctcact accacgatat caaacgtgcc agctatgtcc
     5701 ctgtgacaga cgaagaagcc ttggaaggat tccaactctt gtctcgtgtg gaagggatta
     5761 tcccagcctt ggaatctagc catgctatcg cttttgcggt gaaattggcc aaagaacttg
     5821 gaccagaaaa gtctatgatt gtctgcctat caggtcgtgg ggacaaggat gtggttcaag
     5881 tcaaagaccg cttggaagca gatgcagcaa agaagggaga agctcatgcc taagacacta
     5941 acagaaaaat tgaatgctat taaagcagct ggaaaaggaa tttttgttcc ctatatcatg
     6001 gctggtgacc acgagaaagg tttggacggt cttgctgaaa caattcactt tttagaagat
     6061 ttgggtgtct ctgcaattga agtgggtatt cccttttcag accctgttgc agatggacct
     6121 gttatcgaag aagctggctt gcgcagttta gcccacggga cctctaccca ggctttagtt
     6181 gaaaccttga aaaccattga aacagagatt ccactggtca tcatgaccta cttcaacccc
     6241 ctctttcagt acggtgtgga gaactttgtc aaagatctgg ctgatacagc tgtgaagggc
     6301 ttgattatcc cagacttgcc tcatgaacat gccaactttg tagaaccatt tttggcagat
     6361 acagatatcg ccttgattcc tttagtaagc ttgaccacag gaattgagcg ccagaaagag
     6421 ttgattgaag gggcggaggg attcatctat gccgttgcca tcaatggagt gacagggaaa
     6481 tcaggcaatt accgtgcaga tttggacaag cacttggcgc aacttcatca agtggccgac
     6541 atcccagtct tgacaggttt tggtgtatct agtcaagccg atctggaacg cttcaatgcg
     6601 gtgtcagatg gtgttatcgt cggttcgaaa atagtaaaag ctctccacca aggagagccg
     6661 attcaggact ttatcaaaca agcagtagct taccaaaaat aatcaaacaa gtagcaagta
     6721 agaggaaagg cacgaaagga agtctttcct ttttcttttg caggagaaag gctagtttta
     6781 tagtgaattg aatctggaat attacactac agttcctaaa atattttcag aaagcgattt
     6841 gaatttccca ataaatttgt tcagttttta attgatttta ctatagaaga tataattttc
     6901 taaattactc tgacacagaa ctttaagaaa aagctaatta ttgtagtaat ttatttaaga
     6961 aaatgatata attcattaaa aagtatttgg aggaggaaga attatgttga atcaggatct
     7021 ctttgattcg cttgaggcac aaaaaattgt agatactttg atgaaagggc aaaaagatta
     7081 tgtagatgaa cgtctagaaa aaagagagac aatgatagtg tcgaatggtt atgcatggac
     7141 gcgacctaat catattgata ctgcatttgc atcagcagat ttgtttgagt ataaattaca
     7201 attagcagga cagacttggg gatatttaga atttgaaaca aatacagaaa aatatgggaa
     7261 agtattgtta attataaagg gtaagaagcg acttacgaac caatttcctt tggtacaaaa
     7321 aaataagagt ggctacttat ttgaatatgc tcagatgaat acactttatc ttaatcaaca
     7381 ttcttcctac aaaaatgatg aagatagtca ttcctttcca attcagatgg agttagtttc
     7441 tgatgaaatg attcaagaaa ttgaacaagc tactaaaaat tcgaatatcg aaaaatttat
     7501 gattttaact tatgaggcgg actcagaaaa caatattata tctgtagatg ttgttatgcc
     7561 tgatgcacga actggtcagt tacacttgat tcaagatttg tctgagtata ttcaatcaag
     7621 ttcgtaccat ttcgaagaag ctaaatatca agatattcct aatttttcag aattatcgga
     7681 aacagaagat tttgaaatta ttccaagaat agaaaaacaa gaaggtcaaa agtagtaagg
     7741 agtatgtaaa tgtttaatgg tcgggtattg aaagaattac gactgttaaa tggtttaagt
     7801 agagcagaat tagctcagag aattaattta acggaacaag ccatttggca gtttgagtcc
     7861 aacgaaacga aacctaaatt atcaaccaaa atgcatttgg ccaaccaatt tcatgttgat
     7921 ttaacttatt ttgaacagga agaagagagc attcgatttg attcttctgt aattgccttt
     7981 agaa
//
LOCUS       DAVHTH010000071         7813 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.071, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000071 DAVHTH010000000
VERSION     DAVHTH010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7813)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7813)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7813
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.071"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            complement(75..239)
                     /locus_tag="VVR63_001863"
     CDS             complement(75..239)
                     /locus_tag="VVR63_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000508323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YczI family protein"
                     /protein_id="HEU6129840.1"
                     /translation="MGFYLMVASMLLGLLALKIGFSQFKENKDKFLSILTSLAGLALV
                     LVAVWLGWPK"
     gene            complement(418..2013)
                     /locus_tag="VVR63_001864"
     CDS             complement(418..2013)
                     /locus_tag="VVR63_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6129841.1"
                     /translation="MKRIVFELIFIATTWYIFLPPLNLTSWEFLFFLCGHLLVVAILF
                     GFGKGINLVKTVHVRHGKAEAALNLEGFKINRLGKILLASIGGILLLAALVSLVTSSM
                     FQAKNYANVVTVTEKDFTEFPKSDTSKVPILDRSTAEKIGDRYLGSLTDKVSQYVAAD
                     TYTQLTIDGKPYRVTPLEYADPIKWFNNQAKGIGEYIKVDMVTGNADLVDLKTPIKYS
                     DSEYFNRDVKRHLRLKYPTKIFKTPSFEVDDEGNPFYVATVYQKQFGLAVPRPASVII
                     LDATNGETKEYSLSDVPEWVDRIYPAEETIEQINYNGKYKDGFLNAMISKKNVTQTTK
                     GYNYLSIGNDIYLYTGVTSANADESNLGFILENMRTGEITKYSLASATEESARESAEG
                     AVQEKSYKATFPILINLNDKPLYIMGLKDNAGLVKEYALVDAVEYQNVIVATTVEEML
                     SKYANKNDLEIDNATTESIKGVVADLKSAVIKGDTVYFFKVDGKIYKVKASVSDDLPY
                     LENGRTFEGQVGKDSYLKTFKVQ"
     gene            complement(2025..2435)
                     /locus_tag="VVR63_001865"
     CDS             complement(2025..2435)
                     /locus_tag="VVR63_001865"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEU6129842.1"
                     /translation="MEKKIVKDILFLSQVSQPASQEDLYLARDLQDTLLANRDTCVGL
                     AANMIGVQKRVIIFNLGLVPVVMFNPVLLSFEGSYEAEEGCLSLVGVRSTKRYETIRL
                     AYRDSKWQEQTITLTGFPAQICQHELDHLEGRII"
     gene            complement(2551..3342)
                     /gene="yghU"
                     /locus_tag="VVR63_001866"
     CDS             complement(2551..3342)
                     /gene="yghU"
                     /locus_tag="VVR63_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
                     /protein_id="HEU6129843.1"
                     /translation="MSAYQLPTVWQDEASNQGAFTGLNRPTAGARFEQNLPKGEQAFQ
                     LYSLRTPNGVKVTILLEELLEAGFKEAAYDLYKIAIMDGDQFGSDFVKLNPNSKIPAL
                     LDQSGTEDVRVFESAHILLYLAEKFGAFLPSNPVERVEVLNWLFWQAGAAPFLGGGFG
                     HFFNYAPEKLEYPINRFTMEVKRQLDLLDKELAQKPYIAGNDYTIADIAIWSWYGQLV
                     QGNLYQGSAKFLDASSYQNLVKWAEKIANRPAVKRGLEVTYTEIK"
     gene            complement(3355..6051)
                     /locus_tag="VVR63_001867"
     CDS             complement(3355..6051)
                     /locus_tag="VVR63_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEU6129844.1"
                     /translation="MSKEQKRQAFYTQSPEEVLQAVDATEQGLSSSEAEKRLAEFGHN
                     ELEEGEKRSILVKFIEQFKDLMIIILVAAAILSVVTSGGEDIADAIIILAVVIINAAF
                     GVYQEGKAEEAIEALKSMSSPVARVLRDGHMAEIDSKELVPGDIVALEAGDVVPADLR
                     LIEANSLKIEEAALTGESVPVEKDLSVELATDAGIGDRVNMAFQNSNVTYGRGMGVVV
                     NTGMYTEVGHIAGMLQDADETDTPLKQNLNNLSKVLTYAILVIALVTFVVGVFIQGKN
                     PLGELLTSVALAVAAIPEGLPAIVTIVLSLGTQVLAKRHSIVRKLPAVETLGSTEIIA
                     SDKTGTLTMNKMTVEKVFYDAVLHDSADDIELGLEMPLLRSVVLANDTKIDVEGNLIG
                     DPTETAFIQYALDKGYDVKGFLEKYPRVAELPFDSDRKLMSTVHPLPDGRFLVAVKGA
                     PDQLLKRCLLRDKAGDIAPIDEKVTNLIHTNNSEMAHQALRVLAGAYKIIDSIPENLT
                     SEELENDLIFTGLIGMIDPERPEAAEAVRVAKEAGIRPIMITGDHQDTAEAIAKRLGI
                     IDANDTEGHVLTGAELNELSDEEFEKVVGQYSVYARVSPEHKVRIVKAWQKQGKVVAM
                     TGDGVNDAPALKTADIGIGMGITGTEVSKGASDMILADDNFATIIVAVEEGRKVFSNI
                     QKTIQYLLSANTAEVLTIFLSTLFGWDVLQPVHLLWINLVTDTFPAIALGVEPAEPGV
                     MNHKPRGRKASFFSGGVLSSIIYQGVLQAALVMSVYGLAIAYPVHVGDNHAIHADALT
                     MAFATLGLIQLFHAYNVKSVYQSILTVGPFKSKTFNWSILVSFILLMATIVVEPLEGI
                     FHVTKLDLSQWGIVMAGSFSMIIIVEIVKFIQRKLGFDKNAI"
     gene            6355..7539
                     /gene="mntE"
                     /locus_tag="VVR63_001868"
     CDS             6355..7539
                     /gene="mntE"
                     /locus_tag="VVR63_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family manganese efflux transporter MntE"
                     /protein_id="HEU6129845.1"
                     /translation="MKQSISNLKLAERGAIISISTYLILSAAKLAAGHLLHSSSLVAD
                     GFNNVSDIIGNVALLIGIRMARQPADRDHHFGHWKIEDLASLITSIIMFYVGFDVLRD
                     TIQKILSREETVIDPLGATLGIISAAIMFVVYLYNTRLSKKSNSKALKAAAKDNLSDA
                     VTSLGTAIAILASSFNYPIVDKLVAIIITFFILKTAYDIFIESSFSLSDGFDDRLLED
                     YQKAIMEIPKISKVKSQRGRTYGSNIYLDITLEMNPDLSVFESHEIADQVESMLEERF
                     GVFDTDVHIEPAPIPEDEILDNVYKKLLMREQLIDQGNQLEELLTDDFVYIRQDGEQM
                     DKEAYKTKKELNSAIKDIQITSISQKTKLICYELDGIIHTSIWRRHETWQNIFHQETK
                     KE"
     gene            complement(7682..>7813)
                     /locus_tag="VVR63_001869"
     CDS             complement(7682..>7813)
                     /locus_tag="VVR63_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6129846.1"
                     /translation="EEEMQANGSDFGKLATLQKELDEKNEALLEKYERYEYLSEFDS"
BASE COUNT         2258 a         1756 c         1552 g         2247 t
ORIGIN      
        1 atagtgtagc atatttttta gccacaacca agaaattcat ctgaaaaacc tcggtttgac
       61 cgaggttttt ctatttattt gggccatcct aaccagacag ccacgagaac aagggctagc
      121 ccagctaaac ttgttaagat agataagaat ttatctttgt tctccttgaa ctgagaaaaa
      181 cctatcttca aagcgagcag tccgagtagc attgaagcaa ccatcaaata aaaacccatt
      241 tctttgtcct ccattagtct taatttattt tactataaca tatatttctt aaataaacct
      301 tttttatact caatgaaaat caaagagcaa actaggaaac tagccgcagg ttgctcaaag
      361 cacagctttg aggttgcaga taaagttgac gtggtttgaa gagattttcg cagagtatta
      421 ctgtacttta aaggtcttga gatagctgtc ttttcctact tgaccttcga aggttctacc
      481 attttcaagg taaggaaggt catcggatac tgaggcctta accttgtaaa tcttgccatc
      541 aactttaaag aagtagacgg tgtcgccctt gataacagct gatttgaggt ctgctactac
      601 tcccttgatg ctttctgtcg ttgcattgtc aatttcaagg tcgtttttat tggcatactt
      661 gctgagcatc tcttccactg tagtagcaac gataacattt tggtactcga ctgcgtctac
      721 cagggcgtac tctttgacca agccagcatt gtcctttaag cccatgatgt agagaggctt
      781 gtcattgagg ttgatgagga ttgggaaggt tgctttgtag gatttctcct gaacagcacc
      841 ttctgctgat tcacgggctg attcttctgt cgcagaagcc aagctatact tagtgatttc
      901 tcctgttcgc atattttcaa ggatgaaacc aagattactc tcatccgcat tagccgacgt
      961 cacacctgtg tagagataga tgtcattacc gatagacaag taattatagc ccttggtagt
     1021 ctgggtcacg tttttcttgg aaatcatggc attcaagaaa ccgtccttgt acttgccgtt
     1081 gtagttaatt tgctcaatgg tttcctctgc tggatagatc ctgtccaccc attctggaac
     1141 atctgataag ctgtattcct tggtttctcc atttgtagca tccaagataa tgactgaagc
     1201 aggacgagga acagcaagtc caaattgctt ttggtaaacc gttgctacat agaaaggatt
     1261 gccctcatcg tccacctcaa aagatggagt tttaaagatt ttggtcgggt acttcaagcg
     1321 caggtgacgt ttgacatcac ggttaaaata ctccgagtct gaatacttga ttggtgtctt
     1381 caagtccacc aaatccgcat ttccagttac catgtccacc ttgatatact caccaattcc
     1441 cttggcttga ttgttaaacc atttgatagg gtctgcatat tctagtggtg tgacccgata
     1501 aggtttccca tcaattgtca attgggtata ggtatctgcc gctacgtatt gcgacacctt
     1561 atcggttagg gaacccaagt agcggtctcc aattttttca gcagtacttc tatctaggat
     1621 aggaacctta ctggtgtcac tcttaggaaa ttcagtaaag tctttttccg taaccgtgac
     1681 tacattggca taatttttag cctgaaacat gctagaagtt accaaggaaa ccaaagctgc
     1741 caagagaaga attcctccaa tcgaagctaa cagaattttc cctaaccgat tgattttgaa
     1801 accctcaaga tttaaggcag cttccgcctt accgtggcgc acatgaaccg ttttgacaag
     1861 gtttatcccc ttgccaaagc caaataagat tgccacaact aacaaatgcc cacagaggaa
     1921 gaagagaaat tcccagctgg tcaggttaag gggcggtaaa aagatatacc aggtcgttgc
     1981 gataaaaata agttcaaaga ctattcgttt catttgcttt cctcctaaat aattcgtcct
     2041 tccaagtgat ccagctcatg ctggcaaatc tgagctggga agcctgtcaa ggtaatggtc
     2101 tgttcctgcc acttgctgtc acgataggca agccttatgg tttcataacg cttagttgat
     2161 ctcacaccta ccaaggacaa acagccttct tctgcctcat aagatccttc aaaggacaga
     2221 agcactgggt taaacatgac cacgggaacc aagccaagat taaagataat cacgcgcttc
     2281 tgcaccccaa tcatattggc agctagacca acacaggtat cacgatttgc taagagtgta
     2341 tcctgcaaat ctctggcaag ataaaggtcc tcctgacttg ccggctgaga cacttgagat
     2401 aaaaataaga tatccttcac aattttcttt tccacttcct cacactcctc ttgcttttta
     2461 ctatattata gcaattatag cacaaaagcc gataactgca aaccctttcc ctcaactgta
     2521 gcaaaaagcc atccgaagat gacttttttg ctatttaatt tctgtataag ttacttccaa
     2581 gccacgctta acagctggac gattggcaat tttttctgcc cattttacta gattttgata
     2641 acttgaggca tccaagaatt ttgcagaacc ttggtaaaga tttccttgaa ctaactgtcc
     2701 ataccaagac cagatagcaa tatctgcaat cgtatagtca ttgcctgcaa tataaggttt
     2761 ctgagccaat tccttatcca ataaatccaa ctggcgtttc acttccatcg taaaacggtt
     2821 aataggatat tccaattttt caggagcata attgaagaaa tgtccaaatc ccccacctag
     2881 aaaaggtgct gcacctgctt gccagaatag ccaattcaaa acttctaccc tttccacagg
     2941 attacttggt aaaaaggctc caaatttctc agcaaggtaa agaagaatat gagcagactc
     3001 aaagactctt acatcttcag tacctgactg gtccaataag gctggaatct tggaatttgg
     3061 attgagcttc acaaagtctg atccgaattg atccccatcc atgatagcaa tcttatacaa
     3121 gtcgtaagcc gcttccttaa aaccagcttc tagtaattct tccaataaga tagtaacctt
     3181 cacaccattt ggtgttctca gtgaataaag ctgaaaagct tgttctcctt ttggcaagtt
     3241 ttgttcgaaa cgggcacctg ctgttggtct gtttagcccc gtaaaagctc cttgattact
     3301 agcttcatcc tgccatacgg tcggtaattg atatgctgac atccgaaacc tcccttaaat
     3361 cgcatttttg tcaaaaccga gtttgcgttg aataaactta acgatttcga cgatgataat
     3421 cattgaaaag cttccagcca taacaattcc ccattgtgac aagtctagtt tggttacgtg
     3481 gaagattcct tcaagcggtt ctacaacgat tgttgccatg agaaggataa aggataccaa
     3541 gatggaccag ttaaaggtct tagacttgaa tgggccaact gtcaagatgg attggtagac
     3601 agacttgaca ttgtaggcat ggaagagctg aatcaaacca agggttgcaa aggccatcgt
     3661 tagggcatct gcatgaatag catgattgtc acccacatga actgggtaag caatcgcaag
     3721 gccataaaca ctcataacaa gagctgcttg gagtacacct tgataaatga tagaactcaa
     3781 aacaccacct gagaagaagc ttgccttgcg tccacgtggt ttatgattca tgacaccagg
     3841 ctccgcaggt tcaacaccaa gagcaatagc tgggaaggta tccgttacca agttaatcca
     3901 caaaagatga accggctgca agacatccca accaaacaag gttgatagga agatggttaa
     3961 tacttcagca gtattagcag aaagtaggta ctgaatagtc ttttgaatgt ttgagaagac
     4021 cttacgtcct tcttccactg cgacgataat agtcgcaaag ttatcatctg caagaatcat
     4081 gtcagaagcc cccttagaaa cttctgtacc agtgattccc ataccgatac cgatatcggc
     4141 tgttttcaga gctggcgcgt cattgacacc atcacctgtc atggcaacga ctttaccttg
     4201 tttttgccaa gccttgacga tacgaacctt gtgttctgga gacacacggg cataaacaga
     4261 gtattgacca acgacttttt caaattcttc atctgacagt tcattgagtt cagcaccagt
     4321 taaaacgtga ccttctgtat cgtttgcgtc aatgattccc aaacgtttgg caatggcttc
     4381 cgctgtgtct tggtggtcac ctgtaatcat aattggacgg attcccgctt ccttagccac
     4441 acgaacagcc tcagcggctt caggacgttc agggtcaatc atcccaatca aaccagtaaa
     4501 aattaaatca ttttcaagct cttcagaagt gagattttct ggaatactat cgataatctt
     4561 ataagcacct gcaaggacac gcaaggcttg atgagccatt tcagaattgt ttgtatgaat
     4621 gagatttgta accttctcat caatcggagc aatatcccca gccttatcac gaagaagaca
     4681 acgttttaag agttggtctg gcgcaccctt gactgctaca aggaaacgac catctggcaa
     4741 tgggtgaact gttgacatga gcttacggtc agagtcaaat ggcaattcag ctacacgagg
     4801 atatttctct aagaaacctt tgacatcata gcccttgtcc aaggcatatt ggataaaggc
     4861 tgtttcggtt gggtcaccaa tcaagttacc ttccacatcg attttcgtat cattggccaa
     4921 gacaactgaa cgaagtagtg gcatttcaag acctagttca atatcatcag ctgagtcatg
     4981 tagaaccgca tcgtagaaga ctttttcgac tgtcatcttg ttcatagtca gcgtaccagt
     5041 cttatcagaa gcgatgattt cagttgaacc aagtgtttca actgctggca acttacgaac
     5101 gatggaatgt cgtttggcca aaacttgagt accaagagaa agaacgatgg taacgatagc
     5161 aggaagtcct tctggaatgg ctgcaacggc aagggcaaca gaagtcaaca actcaccaag
     5221 tggatttttc ccttgaatga agacacccac tacaaaagta acaagggcaa tgaccaagat
     5281 agcataggtc aagaccttag aaaggttgtt caaattttgt ttgagtggtg tatcagtctc
     5341 atccgcatct tgaagcatac cagcaatatg accaacttca gtgtacatac ctgtattgac
     5401 aacaacaccc atcccacgac cataggttac gtttgagttt tggaaggcca tgttgacacg
     5461 gtcaccaata ccagcatctg tcgcaagctc gactgacaag tctttttcga ctggtacaga
     5521 ttcacctgtc aaggctgctt cttcaatttt aagagagttg gcttctatca aacgtaggtc
     5581 cgctggtacc acgtcacctg cttcaagggc aacgatatcg cctggtacca attctttaga
     5641 gtcaatctct gccatgtgtc catcacgaag aacgcgggca actggactag acatggattt
     5701 gagggcttca atagcttctt cagcttttcc ttcttggtaa acaccaaagg cagcgttgat
     5761 gataaccaca gctaggatga taatggcatc tgcgatatct tccccaccag aagtcacgac
     5821 tgacaagatt gctgccgcaa ctaggatgat aatcatcaaa tccttaaatt gctcgatgaa
     5881 tttgaccaag attgatcgtt tctcgccttc ttcgagttca ttgtgcccaa attcggcaag
     5941 gcgcttttcc gcctcacttg atgacaaacc ttgctcggtc gcatccacag cctgcaagac
     6001 ctcttcaggg ctctgagtat aaaacgcttg gcgtttttgt tcttttgaca tgtgtctcct
     6061 ccttgacatt gtgtgcaaaa cagactctct ttctgtcata tcttttcacg acaaacaaaa
     6121 agagacctgt taatcataac aagtctcgct gtttaagata gggccggaaa gcatactttt
     6181 cagcataaaa ttcggaatga cgacactatc acaggtttct gccagctact cccttgagta
     6241 gtaccattat accaaatttt ggggagtttt caaagagtaa aaactgcctt atttgaattt
     6301 ttccttgaaa accagtataa tggtagaatg ctatgtgact agaaaggaag ttgaatgaag
     6361 caatctatct caaatctcaa gttagctgag cgtggagcca ttatcagtat ttcgacctat
     6421 ttgatcttgt ctgcagccaa attagcagct ggtcatctcc ttcattcatc cagtttggtg
     6481 gccgatggtt ttaataacgt atcggacatc attggaaatg tagccctctt aatcgggatt
     6541 cggatggcgc gccagcctgc agaccgtgac caccattttg gtcattggaa gattgaagat
     6601 ttggcaagct tgatcacttc tatcatcatg ttctatgtcg gtttcgatgt tctaagagat
     6661 accattcaaa agattctcag tcgggaagaa acggtcattg atcctcttgg tgcaactcta
     6721 ggaatcattt ctgcagcgat tatgtttgtg gtctatctct acaatactcg cctcagtaag
     6781 aaatccaact ccaaggcgct gaaggcagct gctaaggaca atctttctga cgctgttacc
     6841 tcacttggaa ccgccattgc catcctagct agtagtttta attatccgat tgtggataaa
     6901 ctggttgcta tcatcatcac tttctttatc ttgaagactg cctatgatat cttcatcgag
     6961 tcttccttta gtctttcaga tggctttgac gaccgcctgc tcgaggacta ccaaaaggct
     7021 atcatggaaa ttcccaaaat cagcaaggtc aaatcgcaaa gaggtcgcac ctacggtagc
     7081 aacatctacc tggatattac actagagatg aatcctgact tgtctgtttt tgaaagccat
     7141 gaaatcgcgg atcaggtcga gtctatgctg gaggagcgtt ttggcgtctt tgataccgat
     7201 gtccatatcg aaccagcacc tatccctgag gatgaaattt tagacaatgt ctataaaaaa
     7261 ttgcttatgc gtgaacaatt gattgaccaa ggaaaccaac tagaagaact cttgactgat
     7321 gattttgtct atattcgcca agatggagag cagatggata aagaggctta taagaccaaa
     7381 aaagagttaa attctgctat caaggacatt caaattactt ccatcagtca aaaaaccaaa
     7441 ctcatctgct atgagttaga tggtatcatc cataccagta tctggcgtcg ccacgaaacc
     7501 tggcaaaata tctttcatca agaaaccaaa aaagaataga gaaatccttt catgagacgg
     7561 gatttttcta ttcttttata ctcaataaaa atcaaagtgc aaattaggaa gccagtcaca
     7621 ggctgtactt gagtcggcaa tgtgaagccg acatagtttg cactttgatt ttcgaatagt
     7681 cttaactatc aaattcactg agatactcat agcgttcgta tttttcaagg agtgcttcat
     7741 ttttctcatc caattctttt tggagagtag ccagcttacc aaagtcagag ccgttagcct
     7801 gcatttcctc ttc
//
LOCUS       DAVHTH010000072         7659 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.072, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000072 DAVHTH010000000
VERSION     DAVHTH010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7659)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7659)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7659
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.072"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            complement(173..1588)
                     /locus_tag="VVR63_001870"
     CDS             complement(173..1588)
                     /locus_tag="VVR63_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEU6129847.1"
                     /translation="MTIFPDDFLWGGAVAANQVEGAYNEDGKGLSVQDVLPKGGLGEA
                     TENPTEDNLKLLGIDFYHKYKEDISLFSEMGFNVFRTSIAWSRIFPKGDEEEPNEAGL
                     KYYDELFDELHAHGIEPLVTLSHYETPLYLARKYHGWVDRRMIHFYEKFARTVLERYK
                     DKVKYWLTFNEVNSVLELPFTSGGIDIPKENLSKQELYQAIHHELVASSLVTKIAREI
                     NSEFKVGCMVLAMPAYPMTPNPKDVWATHEYENLNYLFSDVHVRGYYPNYAKRYFKEH
                     DINIEFAAEDAELLKNYTVDFLSFSYYMSVTQSALPTQYNSGEGNIIGGLVNPYLESS
                     EWGWQIDPIGLRIILNRYYDRYQIPLFIVENGLGAKDQLIKDEFNNLTVQDDYRIQYM
                     KEHLLQVAEALQDGVEIMGYTSWGCIDCVSMSTAQLSKRYGLIYVDRNDDGNGTFNRY
                     KKMSFTWYKGVIESNGESLFK"
     gene            complement(1601..3439)
                     /locus_tag="VVR63_001871"
     CDS             complement(1601..3439)
                     /locus_tag="VVR63_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEU6129848.1"
                     /translation="MSYKDTVQKILDVIGGEKNVNRVTHCVTRLRLELKDENLVNDDD
                     VKKIPGVIGIMKKNGQYQIILGNDVANYYKEFVKLGNFESDSVVQGHKGNILERIIEY
                     IAGSMTPIIPAMLGGGMLKVLVIILPMLGILQSDSQTIAFLTFFGDAPYYFLPLLLAY
                     SASQKLKVTSTLAMSVAGVLLHPNFVQMVQSGNPLSLFGVPVTPASYGSSVVPILIMV
                     WLMKYIEKMIAKLTPAVTKSFLQPTLVLLVSSCIALVVVGPIGVIVGEGLSNLVGQMY
                     GVAGWLTLAILGAIMPFIVMTGMHWAFAPIFLAASIATPDVLILPAMLGSNLAQGAAS
                     MAVALKSKNNNTKQIAFAAGFSALLAGITEPALYGVTLKYKKPLYAAMIGGGLAGLFA
                     GLTSVKAYLFAVPSLIALPQFIYSDVPSNIVNALIVAVISVVITFVLAYIFGIDEEES
                     SSNLEVKAGVSNKKMIFSPISGEIIPLSDVQDKTFSDKLIGDGVAIIPSEGKVYAPFD
                     GKITNIFPTKHAIGLKSDEGVELLIHIGLDTVELKGQGFISHVEEGDRVFKNQLIFEM
                     DLNLIKTKGYETVTPVIVTNTNDFLDVLVLPNNQTIEHSKELLVIL"
     gene            complement(3457..4131)
                     /locus_tag="VVR63_001872"
     CDS             complement(3457..4131)
                     /locus_tag="VVR63_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEU6129849.1"
                     /translation="MTRFTEMFINVPLELVYITEKIINLGKITLGNNFDEIIYINLTD
                     HISSSIERYKEGIIISNPLRWEISKYYKEEFELGKRALQIIKKELGIELPIDEAAFIA
                     LHFVNANLENNFQESYKITEIIMGIEKIIQDFYCTEFNQDSIDYYRFITHIKLFAHRL
                     VENTTYCDDDDEDLLALMKNKYPREYECGEQVAMFIQTEYNYLLTSSELVYLMAHIRR
                     LTKNLD"
     gene            complement(4139..4297)
                     /locus_tag="VVR63_001873"
     CDS             complement(4139..4297)
                     /locus_tag="VVR63_001873"
                     /inference="COORDINATES: protein motif:HMM:NF015107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6129850.1"
                     /translation="MIIKRILNHNAVIAQSKKDIDILLFGRGIAFGRKTGDKVNPIDI
                     EKSFFSQK"
     gene            complement(4597..7155)
                     /locus_tag="VVR63_001874"
     CDS             complement(4597..7155)
                     /locus_tag="VVR63_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000442363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEU6129851.1"
                     /translation="MERSQFEEMFQLQSSRLTTQEKLQLFTSVFAGRYDVYAKNFINE
                     QGKIQYFPSYDYGWKQLPPEKRSFQTLTNSVLKSHFRGEAAIGIFPMHLDDSCYFLVL
                     DLDEGDWKEAGLTIRRIARERQMEAHLEISRSGYGLHIWFFFEEAILSRKARLFGKKL
                     LELAMQESMQLSFDSFDRMFPNQDVLPKGGFDNLISLPFQGEAYHQGRTVFVDEQFQP
                     YEDQWRYLQEIQKISTAKVALLIQEELGKQELDKELKIVLSNMIQLEKSSVTPKTLFF
                     LKNMASFSNPEFYLKQAMRQPTYQIPERMYLFGESDHYLWLPRGLLYPLQDKFKQVSV
                     EDRRKVQRSISVEFKGELTFEQELALSDMTSKENGLLHAETGFGKTVLGAALISERKT
                     KTIILVHNKQLLDQWLDRLNCFLTFEEEEAIRYTASGREKVIGYVGQYGGTKKWLSKL
                     VDVVMIQSLFKLENSQSLLDEYEMMIVDECHHVSALMFEKVVAQFRGKYLYGLTATPE
                     RKNGHEPIVFQRIGEILHTADKRETDFKRQLQLRFTSFGHLEIEKTKASNFIQLSDWI
                     ATDSARNQLILKDILAQVAEGRNILVLVNRIQQIDVFEKLLKEKEVDGCYIISGKTKV
                     RERTSLLETLEQLDKGFVLLSTGKYIGEGFDLPQLDTLILAAPFSWKNNLIQYAGRIH
                     RNYKDKSLVRIFDYVDIHVPYLEKMFQKRQVAYRKMDYRVIEGEEKQFVYVDSRYEKV
                     LREDLAGERQECLLILPYVHQTKLMNFLKEFRISQIEICIPETVANKAWLDQLKSQKI
                     KVSFTQSKIVTPILLVNKTIVWYGAMPLLGKVDEMTILRLESASIVSELVAGLR"
BASE COUNT         2529 a         1585 c         1064 g         2481 t
ORIGIN      
        1 ccaatctatc ctaagttaac tatttataat cggctctctg taacaaaatt aaattaatta
       61 atccccctat aaaataaaga ggtttagaat ttgatgtctt tcaaacctct ttatttcata
      121 tttaatgaga tgctgcctta accgtgataa tatctaatca tcaataaaca aactatttga
      181 ataaggattc tccatttgat tcaatcactc ctttatacca agtaaaggac attttcttat
      241 atcgattgaa tgtgccattt ccatcatcat ttcgatcaac ataaatgaga ccgtacctct
      301 tagaaagctg tgcagtggac atagaaacgc agtcaataca tccccaagac gtatagccca
      361 taatttccac accatcttgt agagcttcag ctacttgcaa taaatgttct ttcatatact
      421 gaattctata atcatcttgg actgttaagt tattaaattc atcttttatt agttgatctt
      481 tagcacctaa tccgttttcc actataaata atggaatttg ataacggtca taatatctat
      541 ttaaaattat acgtagtcca attggatcaa tttgccatcc ccactcagaa gactctaaat
      601 aaggatttac taagccacca ataatattcc cttctcctga attatactgt gttggaagag
      661 cagattgagt cacactcatg taatagctaa aggataaaaa atctacagta taatttttta
      721 ataactctgc atcttcagct gcaaactcta tgttaatgtc atgttcctta aaatatcttt
      781 ttgcataatt cggataataa cctctaacat gcacatctga aaatagataa tttagattct
      841 catactcatg agtcgcccat acatcttttg gatttggagt cattggataa gctggcatag
      901 ctaataccat acaccccacc ttaaactctg aattaatctc acgagcaatt tttgtaacca
      961 aactcgaggc gactaattca tgatgtatag cttgatataa ttcttgtttc gaaagattct
     1021 ccttaggtat atctattcct ccactagtaa atggtaattc caaaacagag tttacttcgt
     1081 taaatgtaag ccaatattta actttatctt tatacctttc taaaactgtt cgagcaaatt
     1141 tttcataaaa atgaatcatt ctcctatcaa cccatccatg atattttctt gctaaatata
     1201 atggagtctc atagtgtgaa agagttacaa gtggctctat cccgtgagca tgtagttcat
     1261 caaacaattc atcataatat ttcaaaccag cttcgttagg ttcttcctca tctccttttg
     1321 gaaaaattct actccatgca atagaagtac gaaaaacatt aaagcccatt tcagaaaaca
     1381 aggatatatc ttccttatat ttatgataaa aatcaatacc taacaatttt aagttatctt
     1441 ctgtaggatt ttctgttgct tctcctaatc cacctttggg taacacatcc tgaactgata
     1501 agcccttacc atcttcatta tatgctccct ctacttgatt agctgcaaca gctccacccc
     1561 aaagaaaatc atctggaaaa atggtcataa ctttcctcca ttataatatt accagtaatt
     1621 ccttagaatg ctcgattgtc tgattattag gtaatactaa tacatctaga aaatcattgg
     1681 tattcgttac aattactggt gtaactgttt cgtagccttt agtcttgatt aaattcaagt
     1741 ccatttcaaa aatcaactga tttttgaaaa ctctgtctcc ttcttctaca tgactaataa
     1801 aaccttgacc ttttagctca acagtatcta atccaatatg aattagtaac tcaacaccct
     1861 catcactctt caatccaatt gcgtgcttag tcggaaaaat atttgtaatt ttcccatcaa
     1921 atggtgcata aaccttacct tcacttggaa taatcgctac tccgtctcca attagtttat
     1981 ctgaaaatgt tttatcctgg acatcgctta acggaatgat ttctcctgat ataggagaaa
     2041 atatcatttt tttatttgaa actccagctt taacttctaa attgctagaa ctctcttctt
     2101 catcgattcc aaatatataa gctaatacaa aggtaataac aaccgaaata accgccacaa
     2161 ttaaagcatt tacaatattt gatggcacat cagaataaat aaattgaggc aacgctatca
     2221 aagatgggac agcaaataga tacgctttaa cactagtaag acctgcaaat aatcccgcta
     2281 atccaccacc aatcatagct gcataaagcg gttttttata ttttaaagtc acaccatata
     2341 atgcaggttc ggtaatccct gcaagtaagg ctgagaaacc tgctgcaaaa gcaatttgtt
     2401 ttgtattatt atttttactc tttaatgcaa cagccatcga agcagcccct tgagctaagt
     2461 ttgaccctaa cattgctgga agaattaata cgtctggagt agcaatagat gccgccaaaa
     2521 aaataggtgc aaaagcccaa tgcattccag tcataacaat aaatggcata atagcaccaa
     2581 gaatagctaa tgtaagccat ccagctacac catacatttg cccaactaga tttgataatc
     2641 cttcaccaac aattactcca ataggcccga ctacaactaa ggcaatacag cttgatacta
     2701 ataatactag cgtaggttgc aaaaaactct tagtaacagc tggtgttaat ttagcaatca
     2761 ttttttcaat atatttcatc aaccaaacca taataagaat tggaacgact gacgaaccat
     2821 aactagctgg tgtcacaggt acaccaaata aactaagagg attccctgat tgcaccattt
     2881 gaacaaaatt tggatggaga agtacacctg ctacagacat agctaatgta gatgttactt
     2941 ttaatttttg tgatgcagaa taagctaata acagcggtaa gaaataatat ggagcatccc
     3001 caaaaaatgt caaaaaagca atagtctgag aatctgattg caatatacca agcattggta
     3061 aaataattac caagactttc agcatacctc cccctaacat tgctggaatg attggagtca
     3121 tggaaccagc gatatactca atgattcttt ctaaaatatt ccctttgtgc ccttgaacaa
     3181 ctgaatcgga ttcaaaattg ccaagtttaa cgaattcttt ataataatta gctacatcat
     3241 taccaagtat aatttgatat tgtccattct ttttcataat acctattaca cctggtatct
     3301 tcttcacatc atcatcattg actaaatttt catcttttaa ttctaatctt aaacgtgtta
     3361 cacaatgggt aactctattg acattttttt cacctccaat tacatcgagg attttttgta
     3421 ccgtatcttt ataactcatg gtattctcct attctattaa tctaaatttt ttgttaagcg
     3481 acgaatatga gccatcaaat aaactaattc actagaagtc agcaaataat tgtactccgt
     3541 ttgtataaac attgccacct gttcaccaca ttcatattct ctaggatatt tatttttcat
     3601 taatgctaac aagtcttcat catcatcgtc acaataagtt gtattttcaa ccaagcgatg
     3661 ggcaaataat tttatatgag ttatgaatct ataataatca atagaatctt ggttaaactc
     3721 agtacaatag aaatcttgaa tgattttctc aattcccata attatttcag tgattttata
     3781 cgactcttga aaattatttt ctaaattagc attaacaaaa tgtagcgcta tgaatgcagc
     3841 ttcgtcaatt ggaagttcaa tacctaactc tttttttatt atttgtaaag cccttttccc
     3901 aagttcaaat tcttctttat aatatttcga tatttcccag cgtaggggat tcgaaataat
     3961 aatcccttct ttataacgtt ctatgctcga agaaatatga tccgttaaat taatatagat
     4021 aatttcatca aaattattac ccaatgttat tttacctagg ttaattattt tttcggtgat
     4081 gtacaccaac tccaaaggaa cgttaataaa catctctgta aaacgggtca tattatctct
     4141 atttttgaga aaaaaaactt ttctcaatat caattggatt tactttatct ccagtttttc
     4201 ttccaaaagc tattcccctt ccaaaaagaa gaatatcgat atctttttta ctttgcgcaa
     4261 ttacggcatt gtggtttagt attcgtttta tgatcataaa atttcccttt taaaataaaa
     4321 ggaacctact taaaaacatc aagaaacttc ttctgatgtg attaaatagg ttcctgctca
     4381 cttgtattag tgataacatc cttttatttc aatttttaat ggtgacatga agcttaaata
     4441 attaataact ctgtaaccgt ttttatttta tgatatttca atctatttgt caagtactta
     4501 taaaaatttt tttattttgt gtgattcgaa tgtgataatg gcaacagtct cactaaagaa
     4561 atgaaaatca tacatagaaa tttttaaaaa ttttctctat cgtaaacctg ccactagttc
     4621 agaaactata ctagctgatt ccaaacgtaa tatggtcatc tcatctacct tccctaataa
     4681 tggcattgca ccataccaaa caatagtctt attcaccaaa agaataggcg ttactatttt
     4741 tgattgagta aaagacactt taattttctg gctcttcaac tggtctagcc atgctttatt
     4801 tgcaaccgtc tctggtatac atatctcaat ttgactaatc ctaaattctt ttagaaaatt
     4861 catcagtttt gtctggtgca cataaggtaa aataagcaga cattcctgtc tttcccctgc
     4921 taagtcctct ctcaacacct tctcatatct actatcaaca taaacgaatt gtttctcctc
     4981 accctcgatg acacgataat ccatctttcg ataagctact tgtcgtttct gaaacatctt
     5041 ttctaaataa ggaacatgaa tatccacata atcgaaaata cgcaccaaag acttatcctt
     5101 gtagtttcta tgaatccgac ctgcatactg aattaaatta tttttccaag aaaagggtgc
     5161 tgccaagata agcgtgtcca actgaggtaa gtcaaaacct tcgccaatgt attttccagt
     5221 agacaacaaa acaaaccctt tatctaactg ttctaacgtc tccagtaaac tcgttctttc
     5281 tcggactttg gtttttccgc taataatgta acagccatca acctctttct ctttcaataa
     5341 cttttcaaag acatctatct gttgaattcg attaactaaa accaagatat tccgtccttc
     5401 tgccacttgg gctagaatat ccttgagaat caactgattc ctcgctgagt ctgtagcaat
     5461 ccaatcactg agctgtataa aattacttgc tttggtcttt tcaatctcca aatgaccaaa
     5521 agaagtgaat cttaattgca attgccgttt aaaatccgtt tccctcttat cagcagtatg
     5581 gagtatctca ccaattctct gaaaaacaat aggctcatga ccattcttac gctcaggcgt
     5641 agccgtcaaa ccgtaaagat acttccctct aaactgagca acaacttttt caaacatcaa
     5701 ggcagagaca tgatgacact catccacaat catcatctca tactcatcca aaagactttg
     5761 actattttcc aacttaaata gagattgaat cataacgaca tcaaccagtt tactcagcca
     5821 tttcttagtc ccaccgtact gtccaacata gccgattacc ttttcacgac ctgatgccgt
     5881 ataacggata gcctcctcct cttcgaaagt caaaaagcag tttaagcgat ctagccattg
     5941 gtctaagagt tgcttattat ggactagaat aattgttttt gttttccgtt cagagataag
     6001 agcagcacct aaaacggtct tcccaaaacc agtctccgca tgaagtaaac cattttcttt
     6061 agaagtcata tctgacaggg ctaactcttg ctcaaaagtg agttctccct taaattccac
     6121 gctaatagac ctttgtacct ttctcctatc ttccacagat acctgcttaa atttatcttg
     6181 caatggatac agcaaacctc ttggcaacca taaataatga tcggattctc caaataaata
     6241 cattctctca ggaatttgat aggttggctg tcgcatagcc tgctttaaat aaaattcggg
     6301 attagaaaat gaagccatat ttttcaagaa aaacagtgtc ttgggtgtca cagacgattt
     6361 ttcaagttgg atcatattgg ataagacgat cttcaactcc ttgtccaatt cttgcttgcc
     6421 taactcctct tggattaaca gtgccacttt agcagttgaa atcttctgaa tttcttgtag
     6481 atacctccat tgatcttcat aaggctgaaa ctgttcatcc acaaagaccg ttcgcccttg
     6541 atgataagct tctccttgaa aaggaaggga aattaaatta tcaaatccac ctttaggaag
     6601 aacatcctga tttggaaaca tgcgatcaaa agaatcaaag gacagttgca tactttcctg
     6661 catagccaat tctaatagtt tctttccaaa caggcgagcc tttcgactca gaatcgcttc
     6721 ctcaaagaag aaccaaatat ggagtccgta acccgaacga gaaatctcta aatgggcttc
     6781 catctggcgt tccctggcta ttcttcgaat ggttaaacca gcttctttcc aatctccttc
     6841 atccaaatcc agtaccaaaa aataacagct atcatctaag tgcataggaa agataccgat
     6901 agctgcctcc ccacgaaaat gagatttcaa aacggagttc gtcaatgtct ggaaactccg
     6961 tttttcaggt ggcaactgct tccaaccata atcataggaa ggaaaatact gaattttccc
     7021 ttgttcattg ataaaattct tagcataaac atcataacgg ccagcaaaca cagaggtaaa
     7081 caattgtaat ttttcttgcg tcgtcaagcg actactttga agttggaaca tctcctcgaa
     7141 ctgagagcgt tccataacaa actgactctt gtctttaaga cgtttatagt ggaatgaaat
     7201 aagatatgaa caaattgatt aggaaaatca aattaattta tagaaatctt ttagcagtca
     7261 tggcgtccta ttccagattc aaaatgctat acacaagaaa aactcactat ccccattaaa
     7321 agaagaaaag acatcaagga cttctaccac aattccatcc aaagacacaa aaacagccat
     7381 aagagtcacc tccttgattc ctataggctg attataacaa gactggctga aattgtacat
     7441 gaaaataaaa tcctaatagt actcattttg tatgtgacta atattccgtc tcgctccaga
     7501 aggtacgaag taaatagagt ttaaacgagc agtctataaa attcaaaaaa cgcatattat
     7561 caagcgacct aaaactttgg gctctataat atttgtagtg ggtaaattcc ctatggatat
     7621 tatggagcct attttgggta gaaaaaaagt cccataaga
//
LOCUS       DAVHTH010000073         7474 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.073, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000073 DAVHTH010000000
VERSION     DAVHTH010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7474)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7474)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7474
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.073"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            52..693
                     /locus_tag="VVR63_001875"
     CDS             52..693
                     /locus_tag="VVR63_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VIT family protein"
                     /protein_id="HEU6129852.1"
                     /translation="MRAGVLDANDGIISIAGVVIGVASATTNIWIIFLSGFTAILAGA
                     FSMAGGEYVSVSTPKDTEEAAVSREKLLLDQDRELAKKSLYAAYIQNGEFKTSAQLLT
                     NKIFLKNPLKALVEEKYGIEYEEFTNPWHAAISSFVAFFLRSLPPMLSVTIFPSDYRI
                     PATVLIVGVALLLTGYTSARLGKAPTKTAMIRNLAIGLLTMGVTFLLEQLFSI"
     gene            complement(735..2723)
                     /locus_tag="VVR63_001876"
     CDS             complement(735..2723)
                     /locus_tag="VVR63_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6129853.1"
                     /translation="MFRLTNKLAVSNLIKNRKLYYPFALAVLLAVTITYLFYSLTFNP
                     KIAEIRGGTTIQATLGFGMFVVTLASAIIVLYANSFVMKNRSKELGIYGMLGLEKRHL
                     ISMTFKELVLFGILTVGAGIGIGALFDKLIFAFLLKLMKLKVELVATFQMKVVITVLL
                     VFGLIFLGLMFLNALRIARMNALQLSREKASGEKKGRFLPLQTILGSISLGIGYYLAL
                     TVTDPLTALTTFFLAVLLVIFGTYLLFNAGITVFLQILKKNKKYYYQPNNLISVSNLI
                     FRMKKNAVGLATIAILSTMVLVTMSAATSIFNSAESFKKVLNPHDFGVSGQNVEKEDL
                     DKLLSQFASDKGYSVKEKEVLRYSNFGIANQEGTKLTIFEKGQNRVQPKTVFMVFDQK
                     DYENMTGQKLSLSGNEVGLFAKNDGLKGQKALTLNDHQFSVKEEFNKDFIVNHVPNKF
                     NILTTDYNYLVVPDLQAFLDQFPDSAIYNQFYGGMNVDASEEEQLKVAEEYENYLNQF
                     NAQLDTEGSYVYGSNLADASAQMSALFGGVFFIGIFLSIIFMVGTVLVIYYKQISEGY
                     EDRERFIILQKVGLDQKQIKQTIHKQVLTVFFLPLLFAFIHLAFAYHMLSLILKVIGV
                     LDTTMMLIVTLSICAIFLIAYVLIFMITSRSYRKIVQM"
     gene            complement(2725..3483)
                     /locus_tag="VVR63_001877"
     CDS             complement(2725..3483)
                     /locus_tag="VVR63_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6129854.1"
                     /translation="MTLLDVKHVQKIYKTRFQGNQVEALKDIHFTVEKGDYVAIMGES
                     GSGKSTLLNILAMLDKPSRGQVYLNGTDTATIKNSQASSFRREKLGFVFQDFNLLDTL
                     SVKDNILLPLVLSRRPITEMMKKLVVTAENLGINQLQEKYPYEISGGQKQRVAVARAI
                     ITEPEILLADEPTGALDSKSSAALLDVFNEINERGQTILMVTHSTAAASRAKRVLFIK
                     DGILYNQIYRGEKTERQMFQEISDTLTVMASEVN"
     gene            3911..4102
                     /locus_tag="VVR63_001878"
     CDS             3911..4102
                     /locus_tag="VVR63_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6129855.1"
                     /translation="MKHKEHILIGLLYLLSPFIGQLLVEHTHFISTEFTGTAYVICWL
                     SVVISIHHFSKNVLSQQQK"
     gene            complement(4456..4728)
                     /locus_tag="VVR63_001879"
     CDS             complement(4456..4728)
                     /locus_tag="VVR63_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEU6129856.1"
                     /translation="MNSKFYKMRRNRMISGVLAGLSDKWNFDVTLVRFLFAIFTVANF
                     GLGVIIYIILASIMPTKEEIEAEMYGTGPRKRKEAQAIDDNEGWFW"
     gene            complement(4786..5235)
                     /locus_tag="VVR63_001880"
     CDS             complement(4786..5235)
                     /locus_tag="VVR63_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HEU6129857.1"
                     /translation="MKLTDYVKQVSLEDFGRPFIHHVQWNRRLRSTGGRFFPKDGHLD
                     FNPKVYQELGLDVFRKIVRHELCHYHLYFQGKGYQHKDRDFKELLKAVDGLRFVPSLP
                     NSNSKPIKLYRCQSCQQRYQRKRRIDTQRYRCGLCRGKLLLVNQPED"
     gene            complement(5222..7351)
                     /locus_tag="VVR63_001881"
     CDS             complement(5222..7351)
                     /locus_tag="VVR63_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HEU6129858.1"
                     /translation="MDKKYEKISQDLGVTLKQIDTVLSLTAEGATIPFIARYRKDMTG
                     SLDEVAIKAIIDLDKSLTNLNDRKEAVLAKIQEQGKLTKELEEAILVAEKLADVEELY
                     LPYKEKRRTKATIAREAGLFPLARLILQNIVDLEKEAEKFVCEGFATGKEALTGAVDI
                     LVEALSEDVTLRSMTYQEVLRHSKLTSQAKDESLDEKQVFQIYYDFSETVGTMQGYRT
                     LALNRGEKLGVLKIGFEHATDRILAFFATRFKVKNAYIDEVVQQSVKKKVLPAIERRI
                     RTELTEKAEEGAIQLFSDNLRNLLLVAPLKGRVVLGFDPAFRTGAKLAVVDATGKMLT
                     TQVIYPVKPASARQIEEAKKDLADLIGQYGVEIIAIGNGTASRESEAFVAEVLKDFPE
                     VSYVIVNESGASVYSASELARQEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIGV
                     GQYQHDVSQKKLSESLDFVVDTVVNQVGVNVNTASPALLSHVAGLNKTISENIVKYRE
                     EEGKITSRSQIKKVPRLGAKAFEQAAGFLRIPESSNILDNTGVHPENYTAVKELFKRL
                     DIKDLNEEAQSKLKSLSVKEMAQELDLGPETLKDIIADLLKPGRDFRDSFDAPVLRQD
                     VLDIKDLVVGQKLEGVVRNVVDFGAFVDIGIHEDGLIHISHMSRKFIKHPSQVVAVGD
                     LVSVWVKKIDTEREKVNLSLLAPNETD"
BASE COUNT         2217 a         1582 c         1448 g         2227 t
ORIGIN      
        1 tcagaaacaa atcacgaaat tgattcaaat tttgcaggtc gtttaaatat cctgcgtgcg
       61 ggtgttcttg atgctaacga tggaattatt tccattgctg gtgtggttat cggagttgcc
      121 agtgccacga ccaatatctg gattatcttt ttatcaggtt ttacggctat cttagctggt
      181 gccttttcaa tggctggtgg agaatatgta tccgtttcaa ctccaaaaga taccgaggaa
      241 gctgccgttt cgcgagaaaa actcttgcta gaccaagata gggaactagc caaaaaatcc
      301 ctctatgctg cttatatcca aaatggagaa ttcaaaactt ctgcccaact cttgaccaat
      361 aagatctttc ttaaaaatcc actcaaggct ctggtagagg aaaaatatgg gattgagtat
      421 gaagaattta ccaatccttg gcacgctgcc atttctagct tcgttgcctt tttccttaga
      481 agtttgcctc caatgctgtc agtgaccatt tttccaagtg attaccgcat ccctgctacc
      541 gtccttattg tcggtgtggc ccttcttctc actggttaca caagtgctag acttggaaaa
      601 gccccaacca aaacagctat gattcggaac cttgctattg gtctcttgac catgggagtt
      661 accttcctgc tcgaacaact tttcagcatt taaaatacaa gaaatacctc gattttgaag
      721 tcgaggtatc ttttttacat ttgcacaatc ttgcgataac ttcttgaagt aatcatgaaa
      781 atcagcacat aggcgatgag gaagatagcg cagatagaca aggtcacaat caacatcata
      841 gtcgtatcca gtacaccaat cacttttaaa atcaggctaa gcatatggta ggcaaaggcg
      901 agatgtatga aggcaaagag caaaggaagg aagaaaacag ttaaaacctg tttgtggatg
      961 gtttgcttga tttgcttttg gtccaaaccg actttctgca agataataaa gcgttcacgg
     1021 tcttcgtagc cttcagaaat ttgtttgtag tagatgacca gaacagttcc gaccataaag
     1081 ataatggata ggaaaatacc gataaagaag acaccaccaa agagggcact catctgagca
     1141 ctagcatctg ctagattgct accataaaca tagctacctt ctgtgtctaa ttgagcatta
     1201 aattgattga ggtagttttc atactcctca gcgaccttga gttgttcttc ttcgctggca
     1261 tctacattca taccaccgta aaactgatta tagatagccg aatctgggaa ttgatccaaa
     1321 aaggcttgta aatcaggaac aacaaggtaa ttgtaatcag tagtcaagat attaaactta
     1381 tttggaacat ggttgacaat gaaatcttta ttaaattctt ctttgacaga aaattgatga
     1441 tcatttagag ttagagcttt ctgtcctttc agtccgtcat ttttggcaaa gagaccgacc
     1501 tcatttcctg atagagacag tttttgacca gtcatatttt cataatcttt ttggtcaaat
     1561 accatgaaaa ctgtttttgg ttggacacgg ttttgtcctt tttcaaaaat agttaacttg
     1621 gttccttctt gatttgcaat accaaagtta ctgtaacgaa gtacttcttt ctctttgaca
     1681 ctataacctt tgtcacttgc aaactggctc aagagtttgt ccaaatcttc tttttcaaca
     1741 ttttgccctg aaaccccaaa atcatgagga tttagaactt ttttaaagga ttctgcggaa
     1801 ttgaaaatgc ttgtcgctgc tgacatggtt accaaaacca ttgttgacaa aatagcgatg
     1861 gttgctagtc caaccgcatt tttcttcata cggaaaatca agttggaaac agatatgagg
     1921 ttattaggtt ggtaatagta tttcttgttt ttctttaaga tttgtaggaa gactgtaatc
     1981 cctgcattaa acaatagata agtaccaaag ataaccagca aaacagctag gaagaaggtt
     2041 gttagggctg taagaggatc ggttaccgta agggcaagat aatagccaat ccctaaactt
     2101 atggaaccaa gaatcgtttg gagaggaagg aagcgacctt ttttctctcc gctagctttc
     2161 tcacgtgaga gctggagggc attcatacgg gcgattcgaa gggcattcag gaacatgagg
     2221 cctaggaaaa tcaatccaaa gacaagaagt actgtaataa caactttcat ctggaaggta
     2281 gcgaccagtt ccaccttcaa tttcatcagt ttgagtagga aagcgaaaat caacttgtca
     2341 aacaaggctc caataccgat tcctgctcca acagttagaa tcccaaatag cactaactcc
     2401 ttaaaggtca tactgattag atggcgcttc tccaagccta acatgccata tatacccagt
     2461 tccttggaac ggtttttcat gacaaaacta ttggcataga ggacgataat ggctgacgca
     2521 agggtaacga caaacatacc aaatccaagt gttgcttgaa tggtggttcc tccacggatt
     2581 tccgcaatct ttggattgaa ggttagggag taaaagagat aggtgatggt gactgccaag
     2641 agaacagcca gtgcaaaggg atagtagagt ttgcggtttt taatcaagtt cgataccgct
     2701 aacttattgg ttaatcgaaa catactaatt cacctcgctt gccatgacag tcaaggtatc
     2761 agagatttct tggaacatct gacgctctgt cttctctcca cggtagattt ggttgtaaag
     2821 aatgccgtct ttgataaaga gaacacgctt ggccctgcta gcagctgctg ttgagtgggt
     2881 taccatgagg atggtttgcc cacgctcatt gatttcatta aagacatcaa gtaaggctgc
     2941 agatgacttg gaatcaaggg ctcctgttgg ctcgtccgca aggagaattt caggttctgt
     3001 gatgatggcg cgggctactg ctacacgctg tttctgacca ccagaaatct cgtaagggta
     3061 cttctcttgc aattggttaa tacccagatt ctcagctgtc accaccaatt tcttcatcat
     3121 ctccgttata ggtcttcttg acaagacaag cggaagcaag atattgtcct taacagacag
     3181 agtatctagc aagttaaagt cttggaagac aaatcctagc ttttcacgcc ggaaactaga
     3241 agcctgtgaa tttttaatag ttgcggtgtc agttccattc aagtaaacct gaccacgact
     3301 tggtttatcc aacatagcta gaatattgag aagagttgat ttaccagaac cagactcacc
     3361 catgatggca acgtagtcac ccttttctac ggtaaagtga atatccttga gggcttctac
     3421 ttggttgccc tgaaaacgtg ttttataaat tttttgaacg tgttttacat ctaaaagtgt
     3481 catgaaaatc tcctttctta atatcccatc aaatgaaatg tagcttgcat catagtgcat
     3541 cccagctgaa cgcgctcaat ttctttgtga cttggttttc tagttttctt atgtaagatt
     3601 tgtttcatga tgttactcct ttgttcttta tgagtctagt ttacatcaaa aaaagaccgc
     3661 ttgccataac ctaaccttac aaaagagact ttaatcttac atttttgtaa gattgggtga
     3721 aatataagca aaattactta gaaaatgatt tgatttccta tttttaaagt tgtaaaatat
     3781 aagtgtgaaa aggcttactt tgaaaaggag gaagcgggaa ctaacatttt agtaagctta
     3841 cctagataac ataccattca atttaacact tgcaagtcgt tcaacctata aggaaagaag
     3901 gtgcgcttta atgaaacaca aagaacatat actcatcgga cttctctatc tgctctctcc
     3961 attcatcggt cagctcttag ttgaacacac acactttatc agtacagaat ttaccggcac
     4021 tgcttatgtt atttgctggt tatcagttgt tatcagcatc caccattttt ccaaaaatgt
     4081 attgtctcaa cagcaaaaat agattaaaaa actgcgttta aattactgct tttatagtaa
     4141 aatgaaataa gaacaggaca aatcgatcag gacagtcaaa tcgatttcta acaatgtttt
     4201 agaagtatag gtgtcctatt ctagttccaa tccactatag tttgtggatg aagctggcga
     4261 aatattatta atactattca aaaatcaaag tgcaaactat atcaacttca cattgccgac
     4321 taaattacag cctgcggctg gcttcctagt ttgcactttg atttttattg agtataaaag
     4381 taaaaaagct ttaaatcaag cagtttagac tattgattta aagctttttg cgtattccaa
     4441 atcttttgta aaacctcacc aaaaccagcc ttcattatcg tcaatggctt gagcttcttt
     4501 gcgtttacgt gggcctgttc cgtacatttc tgcttcgatt tcttccttgg ttggcatgat
     4561 agaagctagg atgatataga taatcacccc aagtccaaag tttgcgactg taaaaatggc
     4621 aaacagaaaa cgtacaaggg taacatcaaa gttccacttg tctgacagac ctgctaaaac
     4681 tcctgaaatc atgcgatttc gtctcatttt ataaaactta ctgttcatga tatttcctct
     4741 ttctgctagg ttagactagt atatcacgga taggctcggc tttcatcagt cctcaggctg
     4801 atttactaat agcaactttc ctcgacaaag tccacagcga tagcgttggg tatcaatcct
     4861 acgcttacgc tgataccttt gctggcagga ttggcaacga tagagcttga ttggcttgga
     4921 gttactattg ggcaaggatg gtacaaaccg taatccatcc actgctttca acagttcctt
     4981 aaaatcccga tccttgtgtt gatagccttt cccttgaaaa tagaggtgat aatgacagag
     5041 ttcatgtcgg acaattttcc taaaaacgtc caaccccagt tcctgataaa ccttgggatt
     5101 aaaatccaaa tgcccatctt tggggaaaaa tcgcccacct gtcgaacgta gacgcctatt
     5161 ccactggaca tgatggataa aaggtctgcc gaagtcttct agtgaaacct gcttgacgta
     5221 atcagtcagt ttcatttgga gctaggagag acagattaac tttttcacgt tcagtatcaa
     5281 ttttcttaac ccaaacgctc accaaatctc caactgccac cacttgacta gggtgtttga
     5341 taaacttgcg actcatatgg gaaatatgga tgagaccgtc ctcatgaatt ccgatatcaa
     5401 caaaagcacc gaaatcaaca acgttacgca ccactccttc tagcttttgt ccaaccacta
     5461 agtccttgat atctaggaca tcttggcgaa gcacaggtgc gtcaaaggaa tcacggaaat
     5521 ctcgacctgg tttgagaaga tctgcaatga tatctttaag agtttctgga ccaaggtcta
     5581 actcttgcgc catttccttg actgaaagcg acttgagttt gctttgggct tcttcgttta
     5641 ggtctttaat atctaaacgt ttgaagagtt ccttaactgc agtgtaattc tctgggtgaa
     5701 ctcctgtatt atcaaggata ttgctacttt cagggatacg aaggaaacca gctgcctgtt
     5761 caaaggcctt agcccccaaa cgaggaactt tcttgatttg ggagcgtgaa gtgatttttc
     5821 cttcctcctc acggtatttg acaatatttt cagaaattgt tttattgagt ccagccacgt
     5881 gagaaagaag agctgggcta gctgtattaa cattgacacc gacttggtta accaccgtat
     5941 ccacgacaaa gtccagactc tcagatagtt tcttctgact gacatcgtgt tggtattgac
     6001 cgacaccaat tgacttagga tcgattttga ccaattccgc aagaggatct tgcaaacgac
     6061 gggcgataga aatggcagag cgtttttcaa cggtcaagtc tggaaactcc tgacgagcaa
     6121 gttcgctggc agaatagaca gaagcaccac tttcattaac gataacatag ctgacttcag
     6181 ggaaatcttt cagaacttcc gctacaaaag cttcgctttc acgactggcc gttccatttc
     6241 caatggcaat aatctctaca ccgtattgac caattaaatc tgctaaatct ttcttggctt
     6301 cttcgatttg acgagctgat gctggtttaa caggataaat aacctgagtt gtcagcattt
     6361 ttcctgttgc atccacgaca gctagcttgg cacctgtacg aaaggctggg tcaaacccaa
     6421 gaaccacgcg ccctttcagt ggagcaacca agaggagatt gcgcaaattg tcagaaaaaa
     6481 gttggatagc tccctcttca gctttctcag ttaattctgt ccgaatacga cgctcaatag
     6541 caggcaagac ctttttctta acggattgct gaacaacttc atcaatataa gcatttttca
     6601 ccttgaaacg agtagcaaag aaggcaagaa tacggtccgt cgcatgttca aaaccgatct
     6661 tcaagacacc aagtttctcc ccacgattga gagccaaggt acgatagcct tgcatagttc
     6721 caactgtctc tgaaaaatca taataaatct gaaaaacctg cttttcatca agactttcat
     6781 ccttggcttg agaagtgagt ttagagtgtc tcagcacttc ctgataagtc atagaacgca
     6841 aggtcacatc ttccgataag gcttcgacca aaatatcaac tgcaccggtc aaggcttcct
     6901 tgccagtcgc aaatccttca cagacgaact tttcagcttc tttctctaag tcaactatat
     6961 tctgcaaaat caaacgagca agaggaaaga gtccagcttc acgggcaatg gttgccttgg
     7021 tacgacgctt ttccttataa ggaagataga gttcttcaac gtctgctaat ttttcggcaa
     7081 ctaagatagc ttcttccaat tccttggtca acttaccttg ttcttgaatc ttagctaaga
     7141 cagcttcctt acggtcattg agatttgtca gacttttatc caaatcaata atagccttaa
     7201 tcgccacctc atccagacta ccagtcatgt ccttgcgata acgcgcgata aagggaatag
     7261 tcgccccttc agctgtcaaa cttagaacgg tatcaatttg ctttaacgtc actcccaaat
     7321 cctgagagat tttttcatat tttttatcca taaatctatt ataccacaag ctggaaggct
     7381 ttctccaatc cttttcatac tcaataaaaa tcaaaaagca aactaggaag ctagccgtag
     7441 gctgctcaaa atactgtttt gaggttgtgg ataa
//
LOCUS       DAVHTH010000074         7459 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.074, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000074 DAVHTH010000000
VERSION     DAVHTH010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7459)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7459)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7459
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.074"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            122..277
                     /locus_tag="VVR63_001882"
                     /pseudo
     CDS             122..277
                     /locus_tag="VVR63_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
     gene            477..3752
                     /gene="rexB"
                     /locus_tag="VVR63_001883"
     CDS             477..3752
                     /gene="rexB"
                     /locus_tag="VVR63_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HEU6129859.1"
                     /translation="MKLLYTDIRTSLTEILTREAEELVAAGKRVFYIAPNSLSFEKER
                     AVLECLSQQASFSITVTRFAQMARYLVLNDLPAKTTLDDIGLGLAFYKCLAELDPKDL
                     RVYGAIKQDPQLIQQLIELYHEMTKSQMSFLDLENLTDEDKRADLLLIFEKVTAYLNQ
                     GQLAQGSQLSHLIEAIENDKVSSDFNQITLVIDGFTRFSAEEERVVDLLHGKGVEIVI
                     GAYASKKAYTSPFSEGNLYQASVKFLHHLASKYQTPAQDCSQTHEKMDSFDKASRLLE
                     SSYDFSELALDVDEKDRENLQIWSCLTQKEELELVARSIRQKLHENSDLSYKHFRILL
                     GDVASYQLSLKTIFDQYQIPFYLGRSEAMAHHPLTQFVESILALKRYRFRQEDLINLL
                     RTDLYTDLSQSDIDAFEQYIRYLGINGLPAFQQIFTKSHHGKFNLERLNVLRLRILAP
                     LETLFASRKQKAENLLQKWSVFLKEGAVTKQLQDLTTTLEAVEQERQAEVWKAFCHVL
                     EQFATVFAGSQVSLEDFLALLHSGMSLSQYRTIPATVDTVLVQSYDLIAPLTADFVYA
                     IGLTQDNLPKISQNTSLLTDEERQNLNQATEEGVQLLIASSENLKKNRYTMLSLVNSA
                     RKQLFLSAPSLFNESESKESAYLQELIHFGFRRREKRMNHKGLSKEDMGSYHSLLSSL
                     VAYHQQGEMSDTEQDLTFVKVLSRVIGKKLDLQGLENPAIPTSPSSKTLAKDTLQALY
                     PAKQEFYLSTSGLTEFYRNEYSYFLRYVLGLQEELRLRPDARSHGNFLHRIFERALQL
                     PNEDSFDQRLEQAIQETSQEREFEAIYQESLEAQFTKEVLLDVARTTGHILRHNPAIE
                     TIKEEANFGGKDQAFIQLDNGRSVFVRGKVDRIDRLKANGAIGVVDYKSSLTQFQFPH
                     FFNGLNSQLPTYLAALKREGKQNFFGAMYLEMAEPVQSLMAVKSLAGAVVEASKSMKY
                     QGLFLEKESSYLGEFYNKNKANQLTDEEFQLLLDYNAYLYKKAAEKILAGRFAINPYT
                     ENGRSIAPYVQQHQAITGFEANYHLGQARFLKKLDLADGKRLVGEKLKQAWFEKIREE
                     LNR"
     gene            3749..7399
                     /gene="addA"
                     /locus_tag="VVR63_001884"
     CDS             3749..7399
                     /gene="addA"
                     /locus_tag="VVR63_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HEU6129860.1"
                     /translation="MKLIPFLSEEEIQKLQEAEANSSKEQKKTAEQIEAIYTSGQNIL
                     VSASAGSGKTFVMAERILNQLARGVEISQLFISTFTVKAATELKERLEKKISKKIQET
                     DDVDLKQHLGRQLADLPNAAIGTMDSFTQKFLGKHGYLLDIAPNFRILQNQSEQLLLE
                     NEVFHEVFEAHYQGKQKETFSHLLKNFAGRGKDERGLRQQVYKIYDFLQSTSNPQKWL
                     SESFLKGFEKADFTSEKEKLTEQIKQALWDLESFFRYHLDNDAKEFAKAAYLENVQLI
                     LDEIGSLNQESDSQAYQAVLARVVAISKEKNGRALTNASRKADLKPLADAYNEERKTQ
                     FAKLGQLSDQITILDYQERYHQDTWELAKTFQTFMSHFVEAYRQRKRQENAFEFADIS
                     HYTIEILENFPQVRESYQERFHEVMVDEYQDTNHIQERMLELLSNGHNRFMVGDIKQS
                     IYRFRQADPQIFNEKFQRYAQNPQEGKLILLKANFRSSSEVLSATNDVFERLMDQEVG
                     EINYDNKHQLVFANTKLTPNPDNKAEFLLYDKDDTGEEEESQTETKLTGEMRLVIKEI
                     LKLHQEKGVAFKEIALLTSSRSRNDQILLALSEYGIPVKTDGEQNNYLQSLEVQVMLD
                     TLRVIHNPLQDYALVALMKSPMFGFDEDELARLSLQKAEDKVHENLYEKLVNAQKMAS
                     SQKGLIHTALAEKLKQFMDILASWRLYAKTHSLYDLIWKIYNDRFYYDYVGALPNGPA
                     RQANLYALALRADQFEKSNFKGLSRFIRMIDQVLEAQHDLASVAVAPPKDAVELMTIH
                     KSKGLEFPYVFILNMDQDFNKQDSMSEVILSRQNGLGVKYIAKMETGAVEDHYPKTIK
                     LSIPSLTYRQNEEELQLASYSEQMRLLYVAMTRAEKKLYLVGKGSREKLEVKQYPAAK
                     NGKLNSNTRLQARNFQDWLWAISKVFTKDKLNFSYRFIGEDQLTREAIGELETKSPLQ
                     DSSQADNRQSDTIKEALEMLKEVEVYNTLHRAAIELPSVQTPSQIKKFYEPVMDMEGV
                     EIAGQGQSVGKKISFDLPDFSTKEKVTGAEIGSATHELMQRIDLSQQLTLASLTETLK
                     QVQTSQAVRDKINLDKILAFFDTVLGQEILANTDHLYREQPFSMLKRDQKSQEDFVVR
                     GILDGYLLYENKIVLFDYKTDRYDEPSQLVDRYRGQLALYEEALSRAYSIENIEKYLI
                     LLGKDEVQVVKV"
BASE COUNT         2270 a         1576 c         1588 g         2025 t
ORIGIN      
        1 tagattgaaa taagatacga acagcttgat tagggaaatc aaattaattt ctagaaatat
       61 tttagcatcc acggtgtact attatagttt caatttacta tagttcaatc attctatcaa
      121 gaatattgaa tatataaagg cacgtaatat taaaacttct tctgatatcg aattagagtc
      181 cgatgttgat ggcgataaat cagacaatct accagtcgac attaagatac tgggacaaca
      241 cattgaagtg tattccgtac ctaagaaaca atcataaaac tcaaagcctt gttaccgagg
      301 cttttttatt atgtgatttt cagtagccag acttattcta tctaatacaa gtaaagctaa
      361 gtatttaaga tttagcagat gatgaagaaa agaaaggatg gcctaaatat tttaacagat
      421 ttacgaggct aatcatggta taatataggg tgatgaaaaa ttccaacgag gctgagatga
      481 aattacttta tactgatatt cggacttctt tgacagaaat tctaacaaga gaggcagaag
      541 agctagttgc agctggcaag cgggtcttct acattgcccc caactctctt tcttttgaaa
      601 aggaacgcgc cgtgctggaa tgcttgtccc agcaggcttc tttttcgatt accgtcacgc
      661 gctttgctca aatggctcgt tatctggtct tgaatgattt accagctaaa actactcttg
      721 atgatatcgg tcttgggttg gccttttaca aatgccttgc cgaactcgat cccaaggact
      781 tgcgtgttta tggcgctatt aagcaggatc ctcaattgat ccagcagtta attgagcttt
      841 atcatgagat gaccaaatcc cagatgagtt ttttggactt ggagaattta acagatgagg
      901 ataagagggc ggatttactc ttgatttttg agaaagtaac agcctatctt aatcaaggtc
      961 agttagccca gggaagtcag ttgtcccatt tgattgaggc tattgagaat gacaaggtaa
     1021 gtagtgattt taatcaaatc accttggtca ttgacggctt tactcgtttt tctgctgagg
     1081 aagagcgggt tgtggactta cttcacggca aaggtgttga gattgttatc ggggcttatg
     1141 ctagtaagaa agcctatacc agtcctttta gcgagggcaa tctctaccaa gccagcgtaa
     1201 aatttctcca tcatctggct tctaaatacc aaacgcctgc tcaggactgt tctcaaactc
     1261 atgagaagat ggatagtttt gacaaggcct ctcgtttgtt ggagtcttct tatgactttt
     1321 cagaactcgc tttggatgtc gatgagaaag accgtgaaaa tttacaaatc tggtcttgtt
     1381 tgacgcaaaa ggaggagttg gagctagtag cccgtagtat tcgtcagaaa ttacatgaga
     1441 actcagacct gagctacaag cattttcgta ttctcttggg ggatgtagct tcttaccagt
     1501 tatctctcaa aaccattttt gaccagtatc agattccttt ttatcttggt agaagcgaag
     1561 ccatggctca tcatcccttg actcagtttg tcgagtctat tttagcttta aaacgttacc
     1621 gttttcgtca ggaggatttg attaatcttc ttagaactga tttgtatact gacctcagtc
     1681 agtctgatat tgatgctttt gagcaatata tccgctatct tggtatcaat ggcttgccag
     1741 cctttcagca aatcttcacc aaatcccacc atggaaaatt taatcttgag cgtttgaatg
     1801 tcctccgcct gagaatttta gcacctcttg aaaccctctt tgccagccga aaacaaaagg
     1861 ctgaaaacct cctacaaaaa tggagtgtct ttctaaaaga aggagctgtg accaagcagt
     1921 tacaagattt gacaaccact ttggaagctg tagaacagga aagacaagcc gaagtttgga
     1981 aggctttctg ccatgtttta gaacaatttg cgactgtttt tgctggttca caggttagtc
     2041 tggaagactt cctagccttg ctccattctg gaatgagttt gtcccaatac cgtaccattc
     2101 cagcaacagt ggacactgtt ctggtgcaga gttacgattt gattgcacca ttgactgctg
     2161 actttgtcta tgctattgga ctaactcagg acaatttacc aaaaatttct caaaacacca
     2221 gtcttctgac agatgaagaa aggcaaaacc taaaccaagc gaccgaagaa ggcgttcaat
     2281 tactgattgc cagcagtgaa aatctcaaga aaaatcgcta cactatgctt tccttggtca
     2341 attctgctcg taagcagttg ttcttgtcgg ctccaagcct ttttaacgaa agtgaaagta
     2401 aggaatctgc ctatcttcaa gagttgatcc attttggatt taggcggaga gagaagagga
     2461 tgaatcacaa aggactgtct aaggaggata tggggtccta tcacagtctt ttgtctagtc
     2521 tggttgccta tcaccagcag ggtgagatga gcgatactga gcaagatttg acttttgtca
     2581 aggttctgtc gcgtgtcata ggtaaaaaac tagatctgca aggtctggaa aatccagcta
     2641 tcccaaccag tccaagcagc aagaccttag ccaaggacac cttgcaagct ctctatcctg
     2701 ccaaacagga gttttacctg tctacgtcgg gtttgacaga gttttatcgc aatgaataca
     2761 gttatttcct acgctacgtt ttaggcttgc aggaggaatt acgtttgcgt cctgatgccc
     2821 gtagtcacgg gaatttcttg catcgtatct ttgaacgcgc cttacagttg cctaatgaag
     2881 attcctttga ccaacgtcta gaacaagcta ttcaagaaac cagtcaagaa cgcgaatttg
     2941 aagctattta tcaagaaagt ttggaagccc agtttaccaa ggaagttttg cttgatgttg
     3001 cacggacgac tggacatatt ctccgacaca atccagccat cgaaaccatc aaagaagaag
     3061 caaattttgg tggaaaagac caagccttta ttcaattaga caatggacgc agtgtctttg
     3121 tacgaggcaa ggtggaccgg attgaccgtt tgaaagctaa tggagcgata ggagtagtag
     3181 actacaaatc cagtctgact cagttccagt ttcctcattt ctttaatggg ctcaattctc
     3241 agttaccaac ctatcttgct gccctaaaaa gagaagggaa gcagaacttt ttcggcgcca
     3301 tgtacttgga aatggctgaa cctgtccaat ctctgatggc ggtaaaaagt ctggcaggag
     3361 cagtggtaga agccagcaaa tctatgaaat accaagggct cttcttggaa aaagaaagca
     3421 gttatttagg cgaattttat aacaaaaaca aggctaatca actgacagat gaggaatttc
     3481 agctcctact ggactacaat gcctatcttt acaagaaagc tgctgagaag attttagcag
     3541 gccggttcgc catcaatcct tatactgaaa atggcagaag cattgcccca tacgtccagc
     3601 aacatcaggc tattacaggc tttgaagcca attaccatct gggccaagcc cgtttcctaa
     3661 aaaagttgga cctagctgat ggcaagcgtc tggtcggaga aaaactcaag caagcttggt
     3721 ttgaaaaaat aagagaggag ttaaatcgat gaagcttatt ccctttttaa gtgaggagga
     3781 gattcaaaaa ctgcaagaag cagaagcaaa ttcgagcaag gaacaaaaga aaactgccga
     3841 gcaaatcgaa gctatctaca cttctggcca gaatatcctg gtctcagcat cggctggttc
     3901 tggaaagacc tttgtcatgg cagagcgcat tctgaaccaa ttggcgcgtg gtgtcgaaat
     3961 ttctcaactc tttatctcaa cctttaccgt caaggctgca actgaactta aagaacgttt
     4021 agagaaaaaa atcagcaaga aaattcaaga aacagatgat gtcgacctca aacaacactt
     4081 gggacgccag ttggcagacc taccaaacgc tgccattgga accatggact ctttcacaca
     4141 aaaattcctt ggcaaacatg gttatctgct tgatattgca cctaatttcc gtattttaca
     4201 aaaccaaagc gagcaacttc ttctcgaaaa cgaagtcttt catgaggtct ttgaagcgca
     4261 ttaccaaggt aaacagaaag agacctttag tcatttgctg aaaaactttg ctgggcgtgg
     4321 caaggacgaa cggggtctgc gccagcaggt ctataaaatc tatgacttcc tccaatccac
     4381 cagtaatcct caaaagtggt tgagtgaatc tttcctcaaa ggctttgaga aagctgattt
     4441 taccagtgaa aaagaaaaac tgactgagca aatcaaacaa gccctttggg atttggaaag
     4501 ctttttccgt taccatctgg ataacgatgc caaggagttt gcaaaggctg cctatttaga
     4561 aaatgttcag ttaattctgg atgaaattgg ctccctaaat caggagtccg atagtcaggc
     4621 ttatcaggca gtgcttgcgc gtgttgtcgc catctctaag gagaaaaacg gtcgagctct
     4681 gactaatgcc agtcgtaagg ctgatttgaa gcccctggct gatgcctaca acgaagagag
     4741 aaagacccag tttgctaaac taggacaatt atcagaccag ataaccattc tcgactatca
     4801 agaacgttat catcaagaca catgggaact agctaaaacc ttccaaacct ttatgagtca
     4861 ttttgtggag gcttatcgtc agcgcaaacg ccaggaaaat gcctttgaat tcgctgatat
     4921 cagccattac accattgaga ttttagagaa tttcccacaa gttcgtgagt cttatcagga
     4981 gcgcttccat gaagtcatgg tcgatgagta tcaggatacc aaccatattc aagaacggat
     5041 gctggaattg ttgtctaatg gccacaatcg ctttatggtg ggagatatca agcaatccat
     5101 ctatcgtttc cgtcaggcag acccgcagat tttcaatgag aaattccaac gctatgcgca
     5161 aaatccccaa gaaggcaagc tcattctcct caaggcaaat ttccgtagta gttcagaagt
     5221 gctgtcagca accaatgatg tctttgaacg tctcatggac caagaggtcg gcgaaatcaa
     5281 ctatgataac aagcaccagc ttgtttttgc caataccaaa ctgactccca atccagacaa
     5341 caaggcagaa tttctcctct acgacaagga cgatacaggt gaggaagaag agagtcaaac
     5401 agaaacgaaa ctaacaggcg aaatgcgctt agttatcaag gagattctga aacttcatca
     5461 agaaaaaggt gttgccttta aggaaattgc ccttctgacc tccagccgca gtcgtaatga
     5521 ccagattctc ctcgccctgt ctgagtacgg aattcctgtc aaaactgacg gagagcaaaa
     5581 caattatctc caatccctag aagtgcaagt catgctagac actcttcgtg tcattcacaa
     5641 tcccctgcaa gactacgcct tggttgccct tatgaagtct ccaatgtttg gttttgatga
     5701 ggatgagcta gcacgtttgt cccttcagaa agcagaggat aaagtccacg aaaatctcta
     5761 tgagaaactg gtcaatgcac aaaaaatggc aagtagtcaa aaaggcttga ttcacacagc
     5821 tctagctgaa aaactaaagc aattcatgga tatcctagct tcttggcgct tgtatgccaa
     5881 aacccactct ctctatgact tgatttggaa gatttacaac gaccgttttt attatgacta
     5941 tgttggggct ttgccgaatg gtcctgctag gcaggccaat ctctatgccc tagcactgcg
     6001 tgctgatcaa tttgaaaaga gcaatttcaa aggtttgtcg cgttttattc gtatgattga
     6061 ccaagtctta gaagcccagc acgatttggc aagcgtggcc gtcgcaccgc caaaagatgc
     6121 agtagagctc atgaccatcc acaagagtaa agggctggag tttccttacg tctttatcct
     6181 caatatggat caagatttca acaagcaaga ctctatgtca gaagtcattc tcagtcgtca
     6241 gaatggtctt ggtgtcaaat atattgccaa gatggagaca ggggcagtag aagaccacta
     6301 tcctaaaacc atcaaactct ccattcctag tctgacctat aggcagaacg aagaggaatt
     6361 acagctagca agctattctg agcagatgcg tttgctgtat gttgctatga cgcgggctga
     6421 gaaaaagctc tatcttgtcg gcaagggttc tcgtgaaaag ctggaagtca agcaataccc
     6481 agcagccaaa aatgggaaac taaatagcaa tactagactg caagcacgga atttccaaga
     6541 ttggctttgg gctatcagta aagtgtttac taaggacaag ctcaacttta gttatcgttt
     6601 tattggcgaa gatcagttga ccagagaagc tatcggagag ttggaaacca agagtcctct
     6661 ccaagatagc tcccaagcag acaatcgtca gtcagatacc atcaaagaag ctctggaaat
     6721 gctgaaggag gtggaagttt ataatactct tcaccgcgca gctattgaac ttcctagtgt
     6781 tcaaacccca agtcaaatca agaaattcta cgaaccagtt atggatatgg aaggtgtcga
     6841 gattgctggt caaggtcagt cagtaggcaa gaaaatcagc ttcgatttgc cagatttttc
     6901 aaccaaagaa aaggtaactg gagctgagat tggtagtgct actcacgaac tcatgcagag
     6961 aattgacctc agccagcaac taacccttgc tagcctaaca gaaacactca aacaagttca
     7021 aactagccaa gctgtcagag acaagatcaa tcttgataaa attcttgctt tctttgacac
     7081 agtactcggt caggaaattc ttgctaatac cgaccatctc tatcgcgagc aacctttctc
     7141 catgctcaaa cgagaccaaa agagtcagga agactttgtt gtccgtggta tccttgatgg
     7201 ctatctgctt tacgaaaaca aaattgttct gttcgactac aagacagacc gctatgatga
     7261 accaagtcaa ctcgtagacc gctatcgtgg tcagttagct ctatacgaag aggctttatc
     7321 acgagcctat tcgattgaaa atattgaaaa atacttgatt ttactcggta aagacgaggt
     7381 tcaagttgta aaagtataac ttatactctt tgaaaatctc ttcaaaccac gtcagcttcg
     7441 ccttgctgta tatatggtt
//
LOCUS       DAVHTH010000075         7126 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.075, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000075 DAVHTH010000000
VERSION     DAVHTH010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7126)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7126)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7126
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.075"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            226..6660
                     /locus_tag="VVR63_001885"
     CDS             226..6660
                     /locus_tag="VVR63_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HEU6129861.1"
                     /translation="MKKSTVLSLTTAAVILAAYAPNEVVLADTSSSEDALNISDKEKV
                     VLDKETENKEKHEDIHNAIETSKDTEEKKTTVIEEKEVVSKNPVIDTKTSNEEARIKE
                     DSNQSQGDNAHSSANKGTENPKKEDRLVYIAEFKDKESGEKAIKQLSNLKNTKVLYTY
                     DRIFNGSAIETTPDNLDKIKQIEGITSVERAQKVQPMMNHARKEIGVEEAIDYLKSIN
                     APFGKNFDGRGMVISNIDTGTDYRHKAMRIDDDAKASMRFKKEDLKGTDKNYWLSDKI
                     PHAFNYYNGGKITVEKYDDGRDYFDPHGMHIAGILAGNDTEQDIKNFNGIDGIAPNAQ
                     IFSYKMYSDAGSGFAGDETMFHAIEDSIKHNVDVVSVSSGFTGTGLVGEKYWQAIRAL
                     RKAGIPMVVATGNYATSASSSSWDLVANNHLKMTDTGNVTRTAAHEDAIAVASAKNQT
                     VEFDKVNIGGESFKYRNIGAFFDKNKITTNEDGTKAPSKLKFVYIGKGQDQDLIGLDL
                     RGKIAVMDRIYTKDLKNAFKKAMDKGARAIMVVNTVNYYNRDNWTELPAMGYEADEGT
                     KSQVFSISGDDGVKLWNMINPNKKTEVKRNNKEDFKDKLEQYYPIDMESFNSNKPNVG
                     DEKEIDFKFAPDTDKELYKEDIIVPAGSTSWGPRIDLLLKPDVSAPGKNIKSTLNVIN
                     GKSTYGYMSGTSMATPIVAASTVLIRPKLKEMLERPVLKNLKGDDKIDLTSLTKIALQ
                     NTARPMMDATSWKEKSQYFASPRQQGAGLINVANALRNEVVATFKNTDSKGLVNSYGS
                     ISLKEIKGDKKYFTIKLHNTSNRPLTFKVSASAITTDSLTDRLKLDETYKDEKSPDGK
                     QIVPEIHPEKVKGANITFEHDTFTIGANSSFDLNAVINVGEAKNKNKFVESFIHFESV
                     EEMEALNSNGKKINFQPSLSMPLMGFAGNWNHEPILDKWAWEEGSRSKTLGGYDDDGK
                     PKIPGTLNKGIGGEHGIDKFNPAGVIQNRKDKNTTSLDQNPELFAFNNQGINAPSSSG
                     SKIANIYPLDSNGNPQDAQLERGLTPSPLVLRSAEEGLISIVNTNKEGENQRDLKVIS
                     REHFIRGILNSKSNDAKGIKSSKLKVWGDLKWDGLIYNPRGREENAPESKDNQDPATK
                     IRGQFEPIAEGQYFYKFKYRLTKDYPWQVSYIPVKIDNTAPKIVSVDFSNPEKIKLIT
                     KDTYHKVKDQYKNETLFARDQKEHPEKFDEIANEVWYAGAALVNEDGEVEKNLEVTYA
                     GEGQGRNRKLDKDGNTIYEIKGAGDLRGKIIEVIALDGSSNFTKIHRIKFANQADEKG
                     MISYYLVDPDQDSSKYQKLGEIAESKFKNLGNGKEGSLKKDTTGVEHHHQENEESIKE
                     KSSFTIDRNISTIRDFENKDLKKLIKKKFREVDDFTSETGKRIEEYDYKYDDKGNIIA
                     YDDGSALQYETEKLDEIKSKIYGVLSPSKDGHFEILGKISNVSKNAKVYYGNSYKSIE
                     IKATKYDSHSKTMTFDLYANINDIVDGLAFAGDMRFFVKDDNRIKAETKIRMPEKNKE
                     TKAEYPYVSSYGNVIELGEGDLSKNKPDNLTKMESGKIYSDSEKQQYLLKDNIILRKG
                     YALKVTTYNPGKTDMLEGNGVYSKEDIAKIQKANPNLRVLSETTIYADSRNVEDGRST
                     QAVLMSALDGFNIIRYQVFTFKMNDKGEAIDKDGNLVTDSSKLVLFGKDDKEYTGEDK
                     SNVEAIKEDGSMLFIDTKPVNLSMDKNYFNPSKSNKIYVRNPEFYLRGKISDKGGFNW
                     ELRVNESVVDNYLIYGDLHIDNTRDFNIKLNVKDGDIMDWGMKDYKANGFPDKVTDMD
                     GNVYLQTGYSDLNAKAVGVHYQFLYDNVKPEVNIDPKGNTSIEYADGKSVVFNINDKR
                     NNGFDGEIQEQHIYVNGKEYTSFDDIKQITDKTLNIKIVVKDFARNTTVKEFILNKDT
                     GEVSELKPHRVTVTIQNGKEMSSTIVSEEDFILPVYKGELEKGYQFDGWEISGFEGKK
                     DAGYVINLSKDTFIKPVFKKIEEKKEEENKPTFDVSKKKDNPQVNHSQLNESHRKEDL
                     QREDHSQKSDSTKDVTATVLDKNNISSKSTTNNPNKLPKTGTASGAQTLLAAGIMFIV
                     GIFLGLKKKNQD"
BASE COUNT         2792 a          970 c         1373 g         1991 t
ORIGIN      
        1 taatcttatt ttttaacgtg tgctaaaaaa taaattaatg catgttaatt tttcttgaat
       61 taaatttttt taaatgatat actgttttta tggagagata acaattatat ataaatgtac
      121 tactctattt cctagataat acttagtaaa actttttata acaaaggcta gcaaagttaa
      181 agtttattat ctattggaag ttaaataaat atgtaaggaa ttaaaatgaa aaaaagtaca
      241 gtattgtcat taaccacagc tgcagttatt ttagcagcct atgcccctaa tgaggtagtc
      301 ttagcagaca catctagctc tgaagatgct ttaaacatct ctgataaaga aaaagtagta
      361 ttagataagg aaacagaaaa taaagagaaa catgaagata ttcataatgc tatagaaact
      421 tcaaaggata ctgaagaaaa gaaaacaaca gttattgagg aaaaagaagt tgttagtaaa
      481 aatcctgtga tagacactaa aactagcaat gaagaagcaa gaatcaaaga agattccaat
      541 caatcccaag gagataatgc acactcgtct gcaaataaag gcacagaaaa tccgaaaaaa
      601 gaagatagac ttgtctatat tgctgaattt aaagataaag aatctggaga aaaagcaatc
      661 aagcaactat ccaatcttaa gaatacaaaa gttttatata cttatgatag aatttttaac
      721 ggtagtgcca tagaaacaac tccagataac ttggacaaaa ttaaacaaat agaaggtatt
      781 acatcggttg aaagggcaca aaaagtccaa cccatgatga atcatgccag aaaggaaatt
      841 ggagttgagg aagctattga ttacctaaag tctatcaatg ctccgtttgg gaaaaatttt
      901 gatggtagag gtatggtcat ttcaaatatc gatactggaa cagattatag acataaggct
      961 atgagaatcg atgatgatgc caaagcctca atgagattta aaaaagaaga cttaaaagga
     1021 actgataaaa attattggtt gagtgataaa atccctcatg cgttcaatta ttataatggt
     1081 ggcaaaatca ctgtagaaaa atatgatgat ggaagggatt attttgaccc acatgggatg
     1141 catattgcag ggattcttgc tggaaatgat actgaacaag atatcaaaaa ctttaacggc
     1201 atagatggaa ttgcacctaa tgcacaaatt ttctcttaca aaatgtattc tgacgcagga
     1261 tctgggtttg cgggtgatga aacaatgttt catgctattg aagattctat caaacacaac
     1321 gttgatgttg tttcggtatc atctggtttt acaggaacag gtcttgtagg tgagaaatat
     1381 tggcaagcta ttcgggcatt aagaaaagca ggcattccaa tggttgtcgc tacgggtaac
     1441 tatgcgactt ctgcttcaag ttcttcatgg gatttagtag caaataatca tctgaaaatg
     1501 accgacactg gaaatgtaac acgaactgca gcacatgagg atgcgatagc ggtcgcttct
     1561 gctaaaaatc aaacagttga gtttgataaa gttaacatag gtggagaaag ttttaaatac
     1621 agaaatatag gggccttttt cgataagaat aaaatcacaa caaatgaaga tggaacaaaa
     1681 gctcctagta aattaaaatt tgtatatata ggcaaggggc aagaccaaga tttgataggt
     1741 ttggatctta ggggcaaaat tgcagtaatg gatagaattt atacaaagga tttaaaaaat
     1801 gcttttaaaa aagctatgga taagggtgca cgcgccatta tggttgtaaa tactgtaaat
     1861 tactacaata gagataattg gacagagctt ccagctatgg gatatgaagc ggatgaaggt
     1921 actaaaagtc aagtgttttc aatttcagga gatgatggtg taaagctatg gaacatgatt
     1981 aatcctaata aaaaaactga agtcaaaaga aataataaag aagattttaa agataaattg
     2041 gagcaatact atccaattga tatggaaagt tttaattcca acaaaccgaa tgtaggtgac
     2101 gaaaaagaga ttgactttaa gtttgcacct gacacagaca aagaactcta taaagaagat
     2161 atcatcgttc cagcaggatc tacatcttgg gggccaagaa tagatttact tttaaaaccc
     2221 gatgtttcag cacctggtaa aaatattaaa tccacgctta atgttattaa tggcaaatca
     2281 acttatggct atatgtcagg aactagtatg gcgactccaa tcgtggcagc ttctactgtt
     2341 ttgattagac cgaaattaaa ggaaatgctt gaaagacctg tattgaaaaa tcttaaggga
     2401 gatgacaaaa tagatcttac aagtcttaca aaaattgccc tacaaaatac tgcgcgacct
     2461 atgatggatg caacttcttg gaaagaaaaa agtcaatact ttgcatcacc tagacaacag
     2521 ggagcaggcc taattaatgt ggccaatgct ttgagaaatg aagttgtagc aactttcaaa
     2581 aacacggatt ctaaaggttt ggtaaactca tatggttcca tttctcttaa agaaataaaa
     2641 ggtgataaaa aatactttac aatcaagctt cacaatacat caaacagacc tttgactttt
     2701 aaagtttcag catcagcgat aactacagat tctctaactg acagattaaa acttgatgaa
     2761 acatataaag atgaaaaatc tccagatggt aagcaaattg ttccagaaat tcacccagaa
     2821 aaagtcaaag gagcaaatat cacatttgag catgatactt tcactatagg cgcaaattct
     2881 agctttgatt tgaatgcggt tataaatgtt ggagaggcca aaaacaaaaa taaatttgta
     2941 gaatcattta ttcattttga gtcagtggaa gaaatggaag ctctaaactc caacgggaag
     3001 aaaataaact tccaaccttc tttgtcgatg cctctaatgg gatttgctgg gaattggaac
     3061 cacgaaccaa tccttgataa atgggcttgg gaagaagggt caagatcaaa aacactggga
     3121 ggttatgatg atgatggtaa accgaaaatt ccaggaacct taaataaggg aattggtgga
     3181 gaacatggta tagataaatt taatccagca ggagttatac aaaatagaaa agataaaaat
     3241 acaacatccc tggatcaaaa tccagaatta tttgctttca ataaccaagg gatcaacgct
     3301 ccatcatcaa gtggttctaa gattgctaac atttatcctt tagattcaaa tggaaatcct
     3361 caagatgctc aacttgaaag aggattaaca ccttctccac ttgtattaag aagtgcagaa
     3421 gaaggattga tttcaatagt aaatacaaat aaagagggag aaaatcaaag agacttaaaa
     3481 gtcatttcga gagaacactt tattagagga attttaaatt ctaaaagcaa tgatgcaaag
     3541 ggaatcaaat catctaaact aaaagtttgg ggtgacttga agtgggatgg actcatctat
     3601 aatcctagag gtagagaaga aaatgcacca gaaagtaagg ataatcaaga tcctgctact
     3661 aagataagag gtcaatttga accgattgca gaaggtcaat atttctataa atttaaatat
     3721 agattaacta aagattaccc atggcaggtt tcctatattc ctgtaaaaat tgataacacc
     3781 gcccctaaga ttgtttcggt tgatttttca aatcctgaaa aaattaagtt gattacaaag
     3841 gatacttatc ataaggtaaa agatcagtat aagaatgaaa cgctattcgc gagagatcaa
     3901 aaagaacatc ctgaaaaatt tgacgagatt gcgaacgaag tttggtatgc tggcgccgct
     3961 cttgttaatg aagatggaga ggttgaaaaa aatcttgaag taacttacgc aggtgagggt
     4021 caaggaagaa atagaaaact tgataaagac ggaaatacca tttatgaaat taaaggtgcg
     4081 ggagatttaa ggggaaaaat cattgaagtc attgcattag atggttctag caatttcaca
     4141 aagattcata gaattaaatt tgctaatcag gctgatgaaa aggggatgat ttcctattat
     4201 ctagtagatc ctgatcaaga ttcatctaaa tatcaaaagc ttggcgagat tgcagaatct
     4261 aaatttaaaa atttaggaaa tggaaaagag ggtagtctaa aaaaagatac aactggggta
     4321 gaacatcatc atcaagaaaa tgaagagtct attaaagaaa aatctagttt tactattgat
     4381 agaaatattt caacaattag agactttgaa aataaagact taaagaaact cattaaaaag
     4441 aaatttagag aagttgatga ttttacaagt gaaactggta agagaataga ggaatacgat
     4501 tataaatacg atgataaggg aaatattatt gcttatgacg atggtagtgc cttacaatat
     4561 gaaactgaaa aacttgacga aataaaatca aaaatttatg gcgttctaag cccatctaaa
     4621 gatggacact ttgaaattct tggaaagata agcaatgttt ctaaaaatgc caaggtatat
     4681 tatggaaata gctataaatc gatagaaatc aaagcgacta agtatgactc acattcaaaa
     4741 acgatgacat ttgatttata cgctaatatt aatgatattg tggatggatt agcttttgct
     4801 ggagatatgc ggttttttgt taaagatgat aatcgaataa aagctgaaac taaaattaga
     4861 atgcctgaaa aaaataagga aactaaagca gaatatccct atgtatcaag ttatgggaat
     4921 gtaatcgaat taggagaagg agatctttca aagaacaaac cagacaattt aactaaaatg
     4981 gaatctggta aaatctattc tgattcagaa aaacaacaat atctgttaaa ggataacatc
     5041 attctaagaa aaggctatgc actaaaagtg actacctata atcctggaaa aacggatatg
     5101 ttagaaggaa atggagtcta tagcaaggaa gatatagcaa aaatacaaaa ggccaatcct
     5161 aatctaagag tcctttcaga aacaacaatt tatgctgata gtagaaatgt tgaagatgga
     5221 agaagtaccc aagctgtatt aatgtcggct ttggacggct ttaacattat aaggtatcaa
     5281 gtgtttacat ttaaaatgaa cgataaaggg gaagctatcg ataaagacgg aaatcttgtg
     5341 acagattctt ctaaacttgt attatttggt aaggatgata aagaatacac tggagaggat
     5401 aagtccaatg tagaagctat aaaagaagat ggctccatgt tatttattga taccaaacca
     5461 gtaaaccttt caatggataa gaactacttt aatccatcta aatctaataa aatttatgta
     5521 cgaaatccag aattttattt aagaggtaag atttctgata agggtggttt taactgggaa
     5581 ttgagagtta atgaatcggt tgtagataat tatttaatct acggagattt acacattgat
     5641 aacactagag attttaatat taagctgaat gttaaagacg gtgacatcat ggactgggga
     5701 atgaaagact ataaagcaaa cggatttcca gataaggtaa cagatatgga tggaaatgtt
     5761 tatcttcaaa ctggctatag cgatttgaat gctaaagcag ttggagtcca ctatcagttt
     5821 ttatatgata atgttaaacc cgaagtaaac attgatccta agggaaatac tagtatcgaa
     5881 tatgctgatg gaaaatctgt agtctttaac atcaatgata aaagaaataa tggattcgat
     5941 ggtgagattc aagaacaaca tatttatgta aatggaaaag aatatacatc atttgatgat
     6001 attaaacaaa taacagacaa gacactaaac attaagattg ttgtaaaaga ttttgcaaga
     6061 aatacaaccg taaaagaatt cattttaaat aaagatacgg gagaggtaag tgaattaaaa
     6121 cctcataggg taactgtgac cattcaaaat ggaaaagaaa tgagttcaac gatagtgtcg
     6181 gaagaagatt ttattttacc tgtttataag ggtgaattag aaaaaggata ccaatttgat
     6241 ggttgggaaa tttctggttt cgaaggtaaa aaagacgctg gctatgttat taatctatca
     6301 aaagatacct ttataaaacc tgtattcaag aaaatagagg agaaaaagga ggaagaaaat
     6361 aaacctactt ttgatgtatc gaaaaagaaa gataacccac aagtaaacca tagtcaatta
     6421 aatgaaagtc acagaaaaga ggatttacaa agagaagatc attcacaaaa atctgattca
     6481 actaaggatg ttacagctac agttcttgat aaaaacaata tcagtagtaa atcaactact
     6541 aacaatccta ataagttgcc aaaaactgga acagcaagcg gagcccagac actattagct
     6601 gccggaataa tgtttatagt aggaattttt cttggattga agaaaaaaaa tcaagattaa
     6661 gacaaaagct atagaaaaaa atggtttatg tactgagatt agatagtgag gtgatgacat
     6721 agttttgtga aaacggccat ttataactca attatttagt ttacttcact tcactattga
     6781 tactatttgg agttattaat ggacttagtt tagataacta atgaattgat tgaaagggtt
     6841 agtattgaca atattggtca tattgattag aaaatagagt ctatcaaaat ttaaaggcta
     6901 atagaggtga tgagacaatt tcaaggaatt aagtagcgtt tggttgctta attccttttt
     6961 atttggaagg aagtttttcg taaccgccca ataacgaagt ctattggacg gttacgatat
     7021 gatcactgac ttcgtcagtc ttatctacaa cctcaaaact gtgttttgag caacctgcgg
     7081 ctagcttcct agtttactct ttgattttca ttgagtatta gaacag
//
LOCUS       DAVHTH010000076         6990 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.076, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000076 DAVHTH010000000
VERSION     DAVHTH010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6990)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6990)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6990
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.076"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            complement(294..1985)
                     /locus_tag="VVR63_001886"
     CDS             complement(294..1985)
                     /locus_tag="VVR63_001886"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HEU6129862.1"
                     /translation="MNTKELIASELSSIIDSLDQEAILKLLETPKNSEMGDIAFPAFS
                     LAKVERKAPQMIAAELAEKMNSQAFEKVVATGPYVNFFLDKSAISAQVLQAVTTEKEH
                     YADQNIGKQENVVIDMSSPNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGD
                     WGKQFGMLIVAYKKWGDEEAVKAHPIDELLKLYVRINAEAENDPSLDEEAREWFRKLE
                     NGDEEALALWQWFRDESLVEFNRLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLL
                     LESEGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKNEYQFAKSIYVVGQE
                     QSAHFKQLKAVLQEMGYDWSDDITHVPFGLVTKEGKKLSTRKGNVILLEPTVAEAVSR
                     AKVQIEAKNPELENKDQVAHAVGVGAIKFYDLKTDRTNGYDFDLEAMVSFEGETGPYV
                     QYAYARIQSILRKADFKPETAGNYSLNDTESWEIIKLIQDFPRIINRAADNFEPSIIA
                     KFAISLAQSFNKYYAHTRILDESPERDSRLALSYATAVVLKEALRLLGVEAPEKM"
     gene            2121..2567
                     /gene="argR"
                     /locus_tag="VVR63_001887"
     CDS             2121..2567
                     /gene="argR"
                     /locus_tag="VVR63_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEU6129863.1"
                     /translation="MRKRDRHQLIKKMITEEKLSTQKEIQDRLEAHNVCVTQTTLSRD
                     LREIGLTKVKKNDMVYYVLVNETEKIDLVEFLSHHLEGVARAEFTLVLHTKLGEASVL
                     ANIVDVNKDEWILGTVAGANTLLVICRDQHVAKLMEDRLLDLMKDK"
     gene            2618..5152
                     /gene="mutS"
                     /locus_tag="VVR63_001888"
     CDS             2618..5152
                     /gene="mutS"
                     /locus_tag="VVR63_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HEU6129864.1"
                     /translation="MAIEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAVNAA
                     QILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLIEQGYKVAIAEQMEDPKQAVGVV
                     KREVVQVITPGTVVDSSKPDSQNNFLVSIDREGNQFGLAYMDLVTGDFYVTGLLDFTL
                     VCGEIRNLKAREVVLGYDLSEEEEQILSRQMNLVLSYEKESFEDLHLLDLRLATVEQT
                     ASSKLLQYVHRTQMRELNHLKPVIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLF
                     WLLDETKTAMGMRLLRSWIHRPLIDKERIVQRQEVVQVFLDHFFERSDLTDSLKGVYD
                     IERLASRVSFGKTNPKDLLQLATTLSSVPRIRAILEGMEQPTLAYLIAQLDAIPELES
                     LISAAIAPEAPHVITDGGIIRTGFDETLDKYRCVLREGTSWIAEIEAKERENSGISTL
                     KIDYNKKDGYYFHVTNSQLGNVPAHFFRKATLKNSERFGTEELARIEGDMLEAREKSA
                     NLEYEIFMRIREEVGKYIQRLQALAQGIATVDVLQSLAVVAETQHLIRPEFGDDSQID
                     IRKGRHAVVEKVMGAQTYIPNTIQMAEDTSIQLVTGPNMSGKSTYMRQLAMTAVMAQL
                     GSYVPAESAHLPIFDAIFTRIGAADDLVSGQSTFMVEMMEANNAISHATKNSLILFDE
                     LGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHELTSLESSLQHLVNVHVATLEQ
                     DGQVTFLHKIEPGPADKSYGIHVAKIAGLPADLLARADKILTQLENQGTESPPPMRQT
                     SAVTEQISLFDRAEEHPILAELAKLDVYNMTPMQVMNVLVELKQKL"
     gene            5299..>6990
                     /locus_tag="VVR63_001889"
     CDS             5299..>6990
                     /locus_tag="VVR63_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6129865.1"
                     /translation="MLIQKIKTYKWQALASLLMTGLMVASSLLQPRYLQEVLGALLAG
                     KYEAIYSIGAWLIGVAVVGLVAGGLNVVLAAYIAQGVSSDLREDAFRKIQTFSYADIE
                     QFNAGNLVVRMTNDINQIQNVVMMTFQILFRLPLLFIGSFILAVQTLPSLWWVIVLMV
                     VLIFGLTAVMMGMMGPRFAKFQTLLERINAIAKENLRGVRVVKSFVQEKEQFAKFTEV
                     SDELLGQNLYIGYAFSVVEPFMMLVGYGAVFLSIWLVAGMVQSDPSVVGSIASFVNYL
                     SQIIFTIVMVGFLGNSVSRAMISMRRIREILDAEPAMTFKDIPDEELVGSLSFENVTF
                     TYPMDKEPMLKDVSFTIEPGQMVGVVGATGAGKSTLAQLIPRLFDPQEGAIKIGGKDI
                     REVSEGTLRKTVSIVLQRAILFSGTIADNLRQGKGNATLFEMERAANIAQASEFIHRM
                     EKTFESPVEERGTNFSGGQKQRMSIARGIVSNPRILIFDDSTSALDAKSERLVQEALN
                     KDLKGTTTIIIAQKISSVVHADKILVLNQGRLIGQGTHADLVANNAVYREIYETQK"
BASE COUNT         1893 a         1368 c         1659 g         2070 t
ORIGIN      
        1 tggttaggtg aattagtgaa gtgtttaggc aagtgtctct ggttacgacg tcatggcctc
       61 taaatcgatt atatttaggg gtcatgacta gtgaagcagt tagctagttc gcatataagc
      121 ggctagcgtc taacaattag gaactttagt tccaataact ttaagattac gacgttttag
      181 gacataaatc gatcatattt atgtcctaaa actagtgaag cgcctagcca aagtccgaat
      241 aggatttggc gttagttact tagattgctt tgcaatcaag taactttggc gatttacatc
      301 ttctctggcg cttctactcc aagcaagcga agggcttctt tgagaacgac tgcggttgcg
      361 tagctgaggg ctagacggct gtcgcgttct gggctttcat ccaagatacg tgtatgtgca
      421 tagtatttgt taaaggattg agccaggcta attgcaaatt tagcaatgat agaaggttca
      481 aagttatctg ccgcacggtt gataatacgt gggaagtctt gaatgagttt aatgatttcc
      541 cagctttcag tatcattcaa gctatagttg ccagctgttt ctggtttgaa atcggctttg
      601 cgtaagatag attggatacg agcgtaggca tattgaacgt aaggtccagt ttcaccctcg
      661 aaggatacca tagcttctag gtcgaagtcg tatccatttg tacggtcagt tttgaggtca
      721 tagaatttaa tggctccaac cccaacagca tgtgctactt ggtctttgtt ttctagttca
      781 ggatttttag cctcgatttg gaccttggca cggctaacag cctctgcaac agtaggctct
      841 agcaagatga cattcccttt acgagtagag agcttcttcc cttcttttgt aaccagacca
      901 aaaggaacgt gggtaatgtc gtcactccaa tcgtagccca tctcttgcaa gacagctttg
      961 agttgtttaa agtgggcaga ttgctcttga ccaacgacgt agatagattt agcaaattgg
     1021 tattcatttt tacggtagag ggctgcagcc aagtcacgtg tgatatagag agttgcacca
     1081 tcagacttct tgatgagggc tggatgttca attccatatt tctcaagatt cacaacttgg
     1141 gcaccttctg attcaagaag tagtcctttt tcagaaagaa tgtctacaac tgcatccatc
     1201 ttatcattgt agaaggcttc tccgttatag ctgtcaaatt caaccttcaa ttcattgtaa
     1261 aggcggttaa attccactaa actttcatcg cggaaccatt gccaaagagc gagagcttcc
     1321 tcatctccat tttcaagttt acggaaccat tcgcgcgctt cttcatccaa gctagggtca
     1381 ttttcagctt cagcgttgat gcggacatag agtttaagga gttcatcgat tggatgagct
     1441 tttacagctt cttcgtcgcc ccattttttg taggcaacaa tcaacatccc aaattgttta
     1501 ccccagtctc ccaaatggtt gaccttgacc gtttgataac cgattttttg gaaaatatgt
     1561 gacaagctat ctccgataac agttgaacgc aggtggccaa tagaaaatgg tttagcgata
     1621 ttcggactag acatgtcgat aacaacattt tcttgtttgc caatattttg gtcagcatag
     1681 tgttcttttt cagtggtaac agcttgcaat acttgagcag aaatggcaga tttatcaagg
     1741 aaaaagttaa cgtaaggtcc tgttgcgaca actttttcaa aggcttggct gttcattttt
     1801 tcagccagtt cagccgcaat catttgtggt gctttacgtt cgactttggc aagagaaaaa
     1861 gcagggaaag caatgtctcc catttctgag tttttagggg tttccagtaa ctttaaaata
     1921 gcctcttggt ccaggctatc aatgatgcta gataattcgc tagcaatcaa ttcttttgta
     1981 ttcattaaga gctccttttt ggacttttct actattttat cacaatttta aagaaagaag
     2041 aaaaaatttt tgaaatctcc tgtttttttg gtataatatg gttataaata tagttataaa
     2101 tatgcacgca agaggatttt atgagaaaaa gagatcgtca tcagttaata aaaaaaatga
     2161 ttactgagga gaaattaagt acacaaaaag aaattcaaga tcggttggag gcgcacaatg
     2221 tttgtgtgac gcagacaacc ttgtctcgtg atttgcgcga aatcggcttg accaaggtca
     2281 agaaaaatga tatggtgtat tatgtactag taaatgagac agaaaagatt gatttggtgg
     2341 aatttttgtc tcatcattta gaaggtgttg caagagcaga gtttaccttg gtgcttcata
     2401 ccaaattggg agaagcctct gttttggcaa atattgtaga tgtaaacaag gatgaatgga
     2461 ttttaggaac agttgctggt gccaatacct tattggttat ttgtcgagat cagcacgttg
     2521 ccaaactcat ggaagatcgt ttgctagatt tgatgaaaga taagtaaggt cttgggagtt
     2581 gctctcaaga cttatttttg aaaaggagag acagaaaatg gcgatagaaa agctatcacc
     2641 cggcatgcaa cagtatgtgg atattaaaaa gcaatatcca gatgcttttt tgctctttcg
     2701 gatgggtgat ttttatgaat tattttatga ggatgcggtc aatgctgcgc agattctgga
     2761 aatttcctta acgagtcgca acaagaatgc cgacaatccg atccctatgg cgggtgttcc
     2821 ctatcattct gcccaacagt atatcgatgt cttgattgag cagggttata aggtggctat
     2881 cgcagagcag atggaagatc ctaaacaagc agttggggtt gttaaacgag aggttgttca
     2941 ggtcattacg ccagggacag tggtcgatag cagtaagccg gacagtcaga ataatttttt
     3001 ggtttccata gaccgcgaag gcaatcaatt tggcctagct tatatggatt tggtgacggg
     3061 tgacttttat gtgacaggtc ttttggattt cacgctggtt tgtggggaaa tccgtaacct
     3121 caaggctcga gaagtggtgt tgggttatga cttgtctgag gaagaagaac aaatcctcag
     3181 ccgccagatg aatctggtac tctcttatga aaaagaaagc tttgaagacc ttcatttatt
     3241 ggatttgcga ttggcaacgg tggagcaaac ggcatctagt aagctgctcc agtatgttca
     3301 tcggactcag atgagggaat tgaaccacct caaacctgtt atccgctacg aaattaagga
     3361 tttcttgcag atggattatg cgaccaaggc tagtctggat ttggttgaga atgctcgctc
     3421 aggtaagaaa caaggcagtc ttttctggct tttggatgaa accaaaacgg ctatggggat
     3481 gcgtctcttg cgttcttgga ttcatcgccc cttgattgat aaggaacgaa tcgtccaacg
     3541 tcaagaagta gtgcaggtct ttctcgacca tttctttgag cgtagtgact tgacagacag
     3601 tctcaagggt gtttatgaca ttgagcgctt ggctagtcgt gtttcttttg gtaaaaccaa
     3661 tccaaaggat ctcttgcagt tggcgactac cttgtctagt gtgccacgga ttcgtgcgat
     3721 tttagaaggg atggagcaac ctactctagc ctatctcatc gcacaactgg atgcaatccc
     3781 tgagttggag agtttgatta gcgcagcgat tgctcctgaa gctcctcatg tgattacaga
     3841 tgggggaatt atccggactg gatttgatga gactttagac aagtatcgtt gcgttctcag
     3901 agaagggact agctggattg ctgagattga ggctaaggag cgagaaaact ctggtatcag
     3961 cacgctcaag attgactaca ataaaaagga tggctactat tttcatgtga ccaattcgca
     4021 actgggaaat gtgccagccc actttttccg caaggcgacg ctgaaaaact cagaacgctt
     4081 tggaaccgaa gaattagccc gtatcgaggg agatatgctt gaggcgcgtg agaagtcagc
     4141 caacctcgaa tacgaaatat ttatgcgcat tcgtgaagag gtcggcaagt acatccagcg
     4201 tttacaagct ctagcccaag gaattgcgac ggttgatgtc ttacagagtc tggcggttgt
     4261 ggctgaaacc cagcatttga ttcgacctga gtttggtgac gattcacaaa ttgatatccg
     4321 gaaagggcgc catgctgtcg ttgaaaaggt tatgggggct cagacctata ttccaaatac
     4381 gattcagatg gcagaagata ccagtattca actggttaca gggccaaaca tgagtgggaa
     4441 gtctacctat atgcgtcagt tagccatgac ggcggttatg gcccagctgg gttcctatgt
     4501 tcctgctgaa agcgcccatt taccgatttt tgatgcgatt tttacccgta tcggagcagc
     4561 agatgacttg gtttcgggtc agtcaacctt tatggtggag atgatggagg ccaataatgc
     4621 catttcgcat gcgaccaaga actctctcat tctctttgat gaattgggac gtggaactgc
     4681 aacttatgac gggatggctc ttgctcagtc catcatcgaa tatatccatg agcacatcgg
     4741 agctaagacc ctctttgcga cccactacca tgagttgact agtctggagt ctagtttaca
     4801 acacttggtc aatgtccacg tggcaacttt ggagcaggat gggcaggtca ccttccttca
     4861 caagattgaa ccgggaccag ctgataaatc ctacggtatc catgttgcca agattgctgg
     4921 cttgccagca gaccttttag caagggcgga taagattttg actcagctag agaatcaagg
     4981 aacagagagt cctcctccca tgagacaaac tagtgctgtc actgaacaga tttcactctt
     5041 tgatagggca gaagagcatc ctatcctagc agaattagct aaactggatg tgtataatat
     5101 gacacctatg caggttatga atgtcttagt agagttaaaa cagaaactat aaaaccaaga
     5161 ctcactagtt aatctagctg tatcaaggag acttctttga caattctcca cttttttgct
     5221 agaataacat cacacaaaca gaatgaaaat gagctgacgc attgtcgctc ccttttgtct
     5281 attttttaag gagaaagtat gctgattcag aaaataaaaa cctacaagtg gcaggccctg
     5341 gcttcgctcc tgatgacagg cttgatggtt gctagttcac ttctgcaacc gcgttatctg
     5401 caggaagtct taggcgccct ccttgctggg aaatatgaag ctatttatag tatcggggct
     5461 tggttgattg gtgtggccgt agtcggtcta gttgctggtg gactcaatgt tgtcctcgca
     5521 gcctatattg cccaaggagt ttcatccgac cttcgggagg atgccttccg taaaattcaa
     5581 accttttctt atgctgatat tgaacaattt aatgcgggaa atctagtcgt tcgaatgaca
     5641 aatgatatca accagattca gaacgttgtc atgatgacct tccagattct tttcagactt
     5701 cccctcttgt tcatcggttc gtttatccta gcggttcaaa ccttaccttc tctgtggtgg
     5761 gtgattgttc tcatggtagt cttgattttt ggtttgactg ctgtcatgat gggaatgatg
     5821 gggcctcgtt ttgccaagtt tcaaaccctt cttgagcgca tcaatgccat tgccaaggaa
     5881 aatttacgtg gcgttcgtgt ggtcaagtcc tttgtccaag aaaaagagca atttgctaag
     5941 tttacagagg tctcagacga gcttcttggt caaaaccttt acattggtta tgccttttca
     6001 gtagtggaac cctttatgat gttggttggt tacggggcgg tcttcctctc tatttggctg
     6061 gtcgcgggaa tggttcagtc ggatccgtct gttgttggtt ccatcgcttc ttttgttaat
     6121 tacctaagcc agattatctt taccattgtt atggttggat ttttgggaaa ttctgtcagc
     6181 cgtgccatga tttccatgcg tcgtattcga gaaattcttg acgcagagcc agctatgacc
     6241 ttcaaggata tcccagatga agagttggtt ggaagcctta gctttgaaaa tgtgaccttt
     6301 acctatccaa tggacaagga accgatgctg aaagatgtga gctttactat tgaacctggt
     6361 caaatggttg gtgtagttgg agcgactggt gcaggaaagt caaccttggc tcaattgatt
     6421 ccacgtctct ttgatccaca ggaaggggct atcaaaatcg gaggtaagga tattcgagaa
     6481 gtgagtgaag gaaccctgcg taaaacagtt tccatcgttc tccaacgtgc cattcttttt
     6541 agtggaacga ttgcagataa cttgagacag gggaagggaa atgctactct atttgaaatg
     6601 gagcgcgcag ccaatattgc ccaggctagt gaattcattc atcgtatgga gaaaaccttt
     6661 gaaagtccag ttgaagaacg gggaaccaat ttctctggtg gacaaaaaca aaggatgtcg
     6721 attgcgcgtg ggattgtcag caatccacgt attctgattt ttgatgattc gacctcagcc
     6781 ttggatgcca aatcagagcg cttggtgcaa gaagctttga ataaggactt gaaggggacg
     6841 acaaccatta ttattgctca aaaaattagc tcggttgtcc atgcagacaa gatcttggtt
     6901 ctaaatcaag gacgattgat tggtcaaggc acgcatgcag acttggttgc caacaatgcc
     6961 gtttaccgtg aaatctatga aacacagaaa
//
LOCUS       DAVHTH010000077         6934 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.077, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000077 DAVHTH010000000
VERSION     DAVHTH010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6934)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6934)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6934
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.077"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            complement(226..708)
                     /gene="greA"
                     /locus_tag="VVR63_001890"
     CDS             complement(226..708)
                     /gene="greA"
                     /locus_tag="VVR63_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HEU6129866.1"
                     /translation="MAEKTYPMTLEEKEKLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYEAAKDEQAFVEGQISSLETKIRYAEIVNSDAVAQDEVAIGKTVTIQEIGEDE
                     EEVYIIVGSAGADAFAGKVSNESPIGQALIGKKTGDTATIETPVGSYDVKILKVEKTA
                     "
     gene            complement(779..2434)
                     /gene="mltG"
                     /locus_tag="VVR63_001891"
     CDS             complement(779..2434)
                     /gene="mltG"
                     /locus_tag="VVR63_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HEU6129867.1"
                     /translation="MSEKSREEEKLSFKEQILRDLEKVKGYDEVLKEDEAVVRTPANE
                     PSTEELMADSLSTVEEIMRKAPTVPTHPSQGVPASPADEIQRETPGVPSHPSQDVPSS
                     PAEESGSRPGPGPVRPKKLEREYNETPTRVAVSYTTAEKKAEQAGPETPTPATETVDI
                     IRDTSRRSRREGAKPVKPKKEKKSHVKAFVISFLVFLALLSAGGYFGYQYVLDSLLPI
                     DANSKKYVTVGIPEGSNVQEIGTTLEKAGLVKHGLIFSFYAKYKNYTDLKAGYYNLQK
                     SMSTEDLLKELQKGGTDEPQEPVLATLTIPEGYTLDQIAQAVGQLQGDFKESLTAETF
                     LAKVQDETFISQAVAKYPTLLESLPVKDSGARYRLEGYLFPATYSIKESTTIESLIDE
                     MLAAMDKNLSPYYSTIKSKNLTVNELLTIASLVEKEGAKTEDRKLIAGVFYNRLNRDM
                     PLQSNIAILYAQGKLGQNISLAEDVAIDTNIDSPYNVYKNVGLMPGPVDSPSLDAIES
                     SINQTKSDNLYFVADVTEGKVYYANNQEDHDRNVAEHVNSKLN"
     gene            complement(2515..3009)
                     /locus_tag="VVR63_001892"
     CDS             complement(2515..3009)
                     /locus_tag="VVR63_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6129868.1"
                     /translation="MKIRQARLEDLDRIVELEFENFSVEEAIPPSVFEAHLREIQTSF
                     LVAEKEGRIMGYIEGPVGLHRHLQDQSFTEEIKDYSHEPGGYISVTCLSIAKEAQGLG
                     LGQKLLTALKEVALEDERDGINLTCHDYLIAYYEKHGFVNEGQSQSTFAGETWYDMVW
                     EMKK"
     gene            complement(3006..3470)
                     /locus_tag="VVR63_001893"
     CDS             complement(3006..3470)
                     /locus_tag="VVR63_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6129869.1"
                     /translation="MEIPIKIIQASKSDLPEIGALQTSSFPAEKQQLSHILEESIRKC
                     ADTFLLARDENQLLGYILSSPQSDNPQYLKVHSLVIESDHQRQGLGTLLLAALKEVAV
                     ELDYKGIRLESPDELLSYFEMNGFVDEEATLLYATSQGYSMIWFNPFYLEEQ"
     gene            complement(3480..4814)
                     /locus_tag="VVR63_001894"
     CDS             complement(3480..4814)
                     /locus_tag="VVR63_001894"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HEU6129870.1"
                     /translation="MSKTYHFIGIKGSGMSALALMLYQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFDEKNLDGDMEIIAGNAFRPDNNVEIVYADQNGISYKRYHEFLGSFMRD
                     FVSMGVAGAHGKTSTTGMLSHVLSHITDTSFLIGDGTGRGSANAKYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTSLEDVFNAFNDYAKQITKGLFVYGEDAELRKITSDA
                     PIYYYGFEAEGNDFVASDLLRSTTGSTFTVHFRGQNLGQFHIPTFGRHNIMNATAVIG
                     LLYTAGFDLNLVREHLKTFSGVKRRFTEKIVNDTVIIDDFAHHPTEIIATLDAARQKY
                     PSKEIVAVFQPHTFTRTIALLDDFAHALNQADAVYLAQIYGSAREVDHGDVKVEDLAN
                     KINKKHQVITVENVSPLLDHDNAVYVFMGAGDIQTYEYSFERLLSNLTSNVQ"
     gene            complement(4825..5463)
                     /locus_tag="VVR63_001895"
     CDS             complement(4825..5463)
                     /locus_tag="VVR63_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HEU6129871.1"
                     /translation="MKQERFPLVSDDEVMLTEMPVMNLYDESDLISNIKGEYRDKNYL
                     EWAPIAEEKPVKPIEKQVGKPKKAPLGVKKEGKSYAEVAREEARADLKKKRSANYLTQ
                     DFSLARRHSQPSLVRQGNQPTTPFQKENPGEFVKYSQKLTQYSQKLTQSHYILAEEVH
                     SIPTKNEEVSAPAPKKNNYDFLKKSQIYNKKSKQTEQERRVAQELNLTRMTE"
     gene            complement(5511..>6934)
                     /locus_tag="VVR63_001896"
     CDS             complement(5511..>6934)
                     /locus_tag="VVR63_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU6129872.1"
                     /translation="QNLAQDLTHPEDFPLQATQVKADLRDYQEKGIGWLQMLHHYGFG
                     GILADDMGLGKTLQTIAFLTSQVTKESRVLILAPSGLIYNWADEFQKFAPQLDVAVVH
                     GLKASREEILAESHQIYVTSYATFRQDSELYQGMAFDFLFLDEAQVMKNAQTKIAQTL
                     RQFVVPSVFALSGTPIENHLGELWSIFQIVMPGLLPSKKEFMKLPAERVAQFIKPFVM
                     RRKKEEVLTELPDLIEVVYKNELEDQQKAIYLAQLQQMRDHLAQVSEQEFQRSRVEIL
                     SGLMRLRQICDTPALFMEDYQGASGKLDSLRDLLVQVADGGHRVLIFSQFKGMLEKIE
                     QELPDLGLTSFKITGSTPAKERQDMTKAFNQGERDAFLISLKAGGVGLNLTGADTVIL
                     VDLWWNPAVEAQAIGRAHRMGQEETVEVYRLVTKGTIEEKIQELQEQKKHLVSQVLDG
                     TESRGSLTLAEIREILGISEAST"
BASE COUNT         1860 a         1571 c         1336 g         2167 t
ORIGIN      
        1 caatgcacta tacatctaat actcaataaa aatcaaagag caaactagga aactagccgc
       61 aggttgctca aaacactgtt ttgaggttgt agatgaaact gacgaagtca gtaaccatac
      121 atacggcaag gcgacgctga cgtggtttga agagattttc gaagaatagc aaaatggaaa
      181 aaggagtgag tgaagcacat cgcctcccca ctcctttttc tgtttttagg ctgttttttc
      241 aaccttcaag atttttacat catagctacc aacaggcgtt tcaatggttg ctgtatcacc
      301 tgttttcttg ccaatcaagg cctgcccaat tgggctttca tttgaaacct tacctgcaaa
      361 ggcatccgca ccagctgaac ctacgataat ataaacttct tcttcgtcct caccaatttc
      421 ttggatggtg actgttttac caatcgctac ttcgtcctgg gcaactgcgt cgctattgac
      481 gatttcagca tagcggattt ttgtttctaa gctagagatt tgtccttcga caaaggcttg
      541 ttcatcctta gctgcttcgt actcactgtt ttctgaaagg tcaccgtatg aacgggcaat
      601 cttaatgcgt tctaccactt ctggtcgacg aaccaatttc aattcttcta attctttttc
      661 aagtttttcc ttttcctcaa gggtcatagg atatgttttt tctgccattt ttctcaactt
      721 tcttctgata atattttcta aagaaaatta tgtgaagtat aacataattt tagtttgttt
      781 agtttaattt gctgttgaca tgttcagcga cattgcggtc gtggtcttct tgattgttag
      841 catagtagac cttgccttct gtgacatctg ctacaaagta gaggttatcg ctcttagttt
      901 gattgatgct tgactcaatc gcatccagac ttggactatc gactggacca ggcatgagac
      961 ctacattttt ataaacatta taaggtgaat caatgttggt atcaatcgca acatcctcag
     1021 ctagactgat attttgcccc agttttcctt gggcatacaa gattgcaata ttactttgaa
     1081 gtggcatatc acgattcaaa cgattgtaga atacacctgc aatgagctta cgatcttctg
     1141 tcttggcacc ttctttttcg accaaggaag caatggtcaa caactcattg acagtcaagt
     1201 ttttagattt gatagtacta tagtaaggag ataggttctt atccatagca gctaacatct
     1261 catcaatcaa gctctcaata gttgtgcttt ccttgataga gtatgtagct gggaaaaggt
     1321 atccttccaa acgataacgc gcaccgctgt cttttacagg caaactttcc agtaaagtag
     1381 gatatttcgc tactgcttga ctgataaacg tctcatcttg aactttagcc aagaaagtct
     1441 ccgctgtcaa agactctttg aagtcacctt gcaattgacc cacagcttga gcaatctgat
     1501 ccaaggtata accttctgga attgtcaaag tcgcaagtac aggttcttgc ggttcatctg
     1561 ttccaccttt ttgcaactct ttgagtaagt cttctgtact catactcttt tgcaaattgt
     1621 agtaacctgc tttcaagtcg gtataatttt tatacttggc ataaaaacta aaaatcagac
     1681 catgctttac caaaccagct ttttcaagcg tcgtaccgat ttcttgaacg tttgaacctt
     1741 ctggaattcc aaccgtcaca tatttcttag aattagcatc gataggtaat aaggaatcta
     1801 gcacgtactg gtaaccaaag taaccacctg ctgagagcaa ggcaaggaat acaaggaatg
     1861 aaatcacaaa agctttcaca tgtgacttct tctctttctt aggcttaacg ggttttgctc
     1921 cttctctacg gctacgacgt gatgtatctc tgatgatatc cactgtttct gtagcaggcg
     1981 taggtgtttc tggacctgct tgttctgctt ttttctctgc cgtcgtatag gaaacagcta
     2041 cccttgttgg ggtttcattg tattctcttt caagtttctt aggtctaaca ggacctggac
     2101 ctggtcttga tccactttct tccgctggag aagaaggtac atcttgactt ggatgacttg
     2161 gaacaccagg agtttctctt tgaatctcat ctgctggaga agctggtaca ccttgacttg
     2221 ggtgagtagg cacggtagga gcttttctca taatctcctc taccgttgac aaggaatcag
     2281 ccatgagttc ttcagttgaa ggttcatttg caggagtgcg aactactgcc tcatcttctt
     2341 tcagaacttc atcatagcct tttacttttt ctaaatctct cagaatctgc tctttaaagc
     2401 ttaatttctc ttcttctctt gacttttcac tcaaaagttt ttcctccttg ttgataatcc
     2461 ataatattat atcttaaaag tccaaaaaaa gcaatctatg atacttttcc taacttattt
     2521 tttcatttcc cagaccatat cataccatgt ttcccctgca aaggttgact gggactggcc
     2581 ttcgttgaca aatccatgtt tttcatagta ggcgatgaga tagtcatgac aggttagatt
     2641 aatgccatct ctctcatctt caagagcaac ttctttcaag gctgtcagca atttctgacc
     2701 cagtccgagt ccctgtgcct ccttggcaat agacagacag gtcacagaga tataaccacc
     2761 aggctcatga ctatagtctt ttatttcttc tgtaaaagac tggtcttgca gatggcggtg
     2821 caggccaact ggtccttcga tataacccat gattcttcct tctttttcag caaccagaaa
     2881 agaggtctga atttctctca aatgtgcttc aaagacagaa ggaggaatgg cttcttcgac
     2941 cgaaaaattt tcaaattcaa gttcaacaat ccgatccaaa tcttctaatc ttgcttgtct
     3001 gattttcatt gttcctccag ataaaaggga ttaaaccaaa tcatactata gccctggcta
     3061 gttgcataga gcaaagttgc ttcttcatca acaaaaccgt tcatttcaaa ataggaaagc
     3121 agctcatcag gactctccaa acgaatccct ttgtaatcca gctcaactgc cacctctttc
     3181 aaggctgcaa gaagaagtgt tcccaagccc tgtctctgat ggtcagactc gatgactaaa
     3241 gaatgtactt ttagatattg cggattgtct gactggggac ttgataaaat atagcctaaa
     3301 agttgatttt catccctagc tagaagaaag gtatccgcac acttacggat actttcttct
     3361 aaaatatggg aaagttgctg cttttcagct ggaaaagacg aggtctgaag tgcccctatc
     3421 tcaggcaaat cagacttgct tgcctgaatg atcttaattg gaatttccat gggaacatcc
     3481 tattgaacat tgcttgtcaa gttagacaag agacgctcaa atgagtattc ataggtttgg
     3541 atgtctcctg ctcccataaa gacgtaaaca gcattgtcat ggtctaggag tggagaaaca
     3601 ttttcaacag taatcacttg gtgttttttg ttgattttgt tggctaggtc ttctacctta
     3661 acgtcaccat gatctacttc acgagccgag ccataaattt gcgctagata aacagcatct
     3721 gcttggttta aagcatgggc aaagtcgtcc aacaaggcaa tggttcttgt aaaggtatgc
     3781 ggttgaaaga ctgctacaat ttccttgctt gggtatttct gacgagccgc atccaaggtc
     3841 gcaataattt ctgttggatg atgggcaaag tcatcgataa tcactgtatc attgacaatt
     3901 ttctcagtga aacgacgttt aacaccggaa aatgttttca agtgctcacg caccaagttc
     3961 aaatcaaatc ctgctgtgta aagaagacca ataacggctg tcgcattcat gatattgtga
     4021 cgaccaaagg ttggaatgtg gaattgcccc aagttttgtc cacggaaatg aacggtgaag
     4081 gttgaaccag ttgttgaacg aagaagatca ctagctacaa agtcattgcc ttcagcttca
     4141 aaaccataat aataaattgg tgcatcagac gtaatcttac gcaattcagc atcttcacca
     4201 tagacaaaaa gacccttggt gatttgtttg gcatagtcgt taaaggcatt gaaaacatcc
     4261 tcgagacttg tgaaataatc tggatggtca aagtcaatgt tggtgataat agagtattct
     4321 gggtggtaag gcatgaagtg acgctcatat tcgtcagatt caaagacaaa atatttggca
     4381 ttggccgaac cacgacctgt cccatctcca atcaagaagc tggtatctgt aatgtgagac
     4441 aagacatgag acaacatacc tgtcgttgaa gtttttccat gtgctcctgc tactcccatg
     4501 ctaacaaagt cacgcataaa gctacctaga aactcatggt aacgtttgta gctgatacca
     4561 ttttggtccg catagacaat ttcgacgttg ttatctggac gaaaggcatt tccagcgata
     4621 atttccatat caccgtctag attcttttca tcaaaaggaa gaatggtaat tcctgcctgc
     4681 tcaagaccgc gttgggtaaa gtagtacttt tcaacatctg atccctgaac cttgtgcccc
     4741 atctggtaca acatcaaggc caaggcactc atccctgatc ccttaattcc gataaaatga
     4801 tatgtctttg acatgttttc tcccctattc tgtcattctg gtcagattca actcttgggc
     4861 aacccgacgt tcttgttctg tttgtttact ttttttattg tagatttggc tcttctttag
     4921 aaaatcataa ttgtttttct ttggagcagg tgctgacact tcttcattct tggtagggat
     4981 agaatgaact tcttccgcca agatataatg agactgggtc aatttttggc tatactgggt
     5041 caatttttgg ctatatttga caaattcacc aggattttcc ttttggaaag gagttgtcgg
     5101 ttgattgccc tgtctaacta gactgggctg agaatgacgt ctcgcaaggc tgaaatcctg
     5161 agttagatag ttagcagagc gtttcttttt caagtctgca cgcgcttctt cacgcgccac
     5221 ctccgcatag ctctttcctt cttttttaac ccctaaagga gcttttttag gtttccctac
     5281 ttgcttttca atcggtttta ctggtttttc ttcagcaata ggagcccatt ctaaataatt
     5341 tttatctcga tactcaccct tgatattact gatcagatca gactcatcat agagattcat
     5401 gactggcatt tcagtcaaca tgacctcgtc atctgacacc aatggaaatc gttcttgttt
     5461 cattttctat ttcctttcaa cacttcatta tagcgtattg tcttgatttt tcaagtgctg
     5521 gcttcagaaa ttcccaaaat ttctctaatt tctgctaggg tcagactacc acgtgactct
     5581 gtgccgtcca atacttgtga caccagatgt ttcttttgtt cttggagttc ctgaattttt
     5641 tcttcaatgg ttcccttggt caccaagcga tagacctcaa ccgtttcttc ctgacccatc
     5701 cgatgggcac ggccaatggc ttgcgcttcc accgcaggat tccaccaaag gtcaaccaag
     5761 atcactgtat ctgcacctgt caggttcaga ccgaccccac cagccttgag ggaaatcaga
     5821 aaggcatctc tttctccttg gttaaaggcc ttggtcatgt cttgtctttc cttggctggg
     5881 gttgaacccg taattttaaa ggatgtcagg cccaagtctg gcagttcttg ttcaattttt
     5941 tccaacattc ccttgaactg agagaaaatc aagacacggt gtccgccgtc tgccacctgt
     6001 accagtaggt ctcggagact atctagtttg ccgctggctc cctgataatc ttccataaac
     6061 agggcaggag tgtcacatat ttgacgcaag cgcatcaaac cagataaaat ttccacacga
     6121 cttcgctgaa attcctgttc tgacacttga gccagatggt ctcgcatctg ttgtaactgg
     6181 gcaaggtaaa tagccttttg ctggtcttcc agttcatttt tataaaccac ctcaatcaag
     6241 tctggcaatt cagtcagaac ttcttctttc ttgcgtcgca tcacgaaagg cttgataaac
     6301 tgagccactc gctctgctgg caatttcata aattctttct tgcttggcaa aagtccgggc
     6361 atgacgattt gaaaaataga ccacaactca cccagatggt tttcaatcgg agttcctgac
     6421 aaggcaaaga ccgacggcac cacaaattgt ctcaaggtct gggcaatctt ggtctgggca
     6481 tttttcatga cctgagcttc atctaagaaa aggaagtcaa aggccatccc ctgataaagc
     6541 tcactgtcct gacggaaggt ggcatagcta gtcacataga tttgatggct ctcggcaaga
     6601 atctcctcac gacttgcttt caaaccatga acaacagcca catccaactg tggagcaaat
     6661 ttctgaaact catctgccca gttgtaaatc aaacccgacg gagcgagaat caaaacccga
     6721 ctttcttttg tcacttgact agtcaaaaaa gcaatggtct gaagggtttt cccaagtccc
     6781 atatcatcag ccaaaatccc accaaaacca taatgatgga gcatctgcaa ccagccaatt
     6841 cccttttcct gataatctcg caagtcagcc ttgacctgag ttgcttgcaa aggaaagtcc
     6901 tctggatgcg tcaaatcctg ggccagattc tgga
//
LOCUS       DAVHTH010000078         6915 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.078, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000078 DAVHTH010000000
VERSION     DAVHTH010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6915)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6915)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6915
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.078"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            complement(112..387)
                     /locus_tag="VVR63_001897"
     CDS             complement(112..387)
                     /locus_tag="VVR63_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HEU6129873.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVEAVFAAVADYLAAGEKVQ
                     LIGFGNFEVRERAERKGRNPQTGKEMTIAASKVPAFKAGKALKDAVK"
     gene            complement(494..1333)
                     /locus_tag="VVR63_001898"
     CDS             complement(494..1333)
                     /locus_tag="VVR63_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEU6129874.1"
                     /translation="MTKIKIVTDSSVTIEPELVKQLDITIVPLSVMIDNVVYSDADLK
                     EEGKFLQLMQESKNLPKTSQPPVGVFAEIFEDLCKDGGQILAIHMSHALSGTVEAARQ
                     GASLSTADVTVVDSSFTDQALKFQVVEAAKLAQEGKDMEAILSHVEEVKNHTELYIGV
                     STLENLVKGGRISRVTGLLSSLLNIRVVMQMKDHELQPMVKGRGTKTFKKWLDELITS
                     LSERAVAEIGISYSGSDDWAKEMKESLQAYVEKPISVLETGSIIQTHTGENAWAILIR
                     YHS"
     gene            1475..2323
                     /locus_tag="VVR63_001899"
     CDS             1475..2323
                     /locus_tag="VVR63_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEU6129875.1"
                     /translation="MIKKIYPIFTILLGAAIYAFGLTYFVVPHHLFEGGATGITLITF
                     YLFKIPVSLMNLLINIPLFILAWKIFGAKSLYSSLLGTLALSAWLAFFEHIPLHIDLQ
                     GDLLITALIAGILLGIGLGIIFNAGGTTGGTDILARILNKYTHISIGKLLFILDFCIL
                     MLILLIFKDLRLVSYTLLFDFIVSRVIDLIGEGGYAGKGFMIITKRPDQLAKAINDDL
                     GRGVTFISGQGYYSKENLKIIYCIVGRNEIVKTKEMIHRIDPQAFITITEAHEILGEG
                     FTFEKE"
     gene            complement(2416..3333)
                     /locus_tag="VVR63_001900"
     CDS             complement(2416..3333)
                     /locus_tag="VVR63_001900"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HEU6129876.1"
                     /translation="MIITIPIKNQKDIGTPSDSVVVLGYFDGIHKGHQELFRVANKAA
                     RKDLLPIVVMTFNESPKIALEPYHPDLFLHILNPAERERKLKREGVEELYLLDFSSQF
                     ASLTAQEFFATYIKAMNAKIIVAGFDYTFGSDKKTAEDLKDYFDGEVIIVPPVEDEKG
                     KISSTRIRQAILDGNVKEAGKLLGAPLPSRGMVVHGNARGRTIGYPTANLVLLDRTYM
                     PADGVYVVDVEIQRQKYRAMASVGKNVTFDGEEARFEVNIFDFNQDIYGETVMVYWLD
                     RIRDMTKFDSVDQLVDQLKADEEVTRNWS"
     gene            3770..3975
                     /locus_tag="VVR63_001901"
                     /pseudo
     CDS             3770..3975
                     /locus_tag="VVR63_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844775.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
     gene            complement(4286..4579)
                     /gene="rpmA"
                     /locus_tag="VVR63_001902"
     CDS             complement(4286..4579)
                     /gene="rpmA"
                     /locus_tag="VVR63_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HEU6129877.1"
                     /translation="MLKMTLNNLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVTG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            complement(4596..4940)
                     /locus_tag="VVR63_001903"
     CDS             complement(4596..4940)
                     /locus_tag="VVR63_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HEU6129878.1"
                     /translation="MIQAVFERAEDGELRSAEITGHAESGEYGLDVVCASVSTLAINF
                     INSIEKFAGYEPILELNEDEGGYLMVEIPKDLPSHQREMTQLFFESFFLGMANLSENY
                     SEFVQTRVITEN"
     gene            complement(4956..5270)
                     /gene="rplU"
                     /locus_tag="VVR63_001904"
     CDS             complement(4956..5270)
                     /gene="rplU"
                     /locus_tag="VVR63_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HEU6129879.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAVYVEKLNVEAGQEVTFNEVVLVG
                     GENTVVGTPLVAGATVVGTVEKQGKQKKVVTYKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     misc_feature    complement(5306..5393)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            complement(5452..6156)
                     /locus_tag="VVR63_001905"
     CDS             complement(5452..6156)
                     /locus_tag="VVR63_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004241810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HEU6129880.1"
                     /translation="MGGKMRLLPIRKISRQSKRLALFLTFCAGYVDAYTFIVRGNTLV
                     AGQTGNVVFLSVELIKNNVSDVRDKVLTLLAFMMGVFLLTIYKEKLRIVKKPILSLIP
                     LAILSIIIAFVPQTVDNIYLVPPLAFCMGLVTTAFGEVSGIAYNNAFMTGNIKRTMLA
                     FGDYFRTKHTPFLREGFIFVSLLSSFVLGVVFSAYLTIFYHEKTILGVPIMMSVFYLS
                     MLFASWQKKVKEKASF"
     gene            6558..6857
                     /locus_tag="VVR63_001906"
     CDS             6558..6857
                     /locus_tag="VVR63_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HEU6129881.1"
                     /translation="MMNMQNMMRQAQKLQKQMEQSQAELAAMQFVGKSAQDLVQATLT
                     GDKKVVSIDFNPAVVDPEDLETLSDMTVQAINSALEQIDETTKKKLGAFAGKLPF"
BASE COUNT         2177 a         1404 c         1151 g         2183 t
ORIGIN      
        1 aatattttcg gaacattcaa ctttttaact ctatttatta ctagatttca taattaaaaa
       61 gcctactgac caagctagaa agcttgatac aataggcttt ttaaagactg attatttaac
      121 agcgtcttta agagctttac cagctttgaa tgctggtact ttagaagctg caattgtcat
      181 ttctttacca gtttgtgggt tgcgaccttt acgttctgcg cgctcacgaa cttcaaagtt
      241 accaaaaccg atcaactgaa ctttttcacc agctgcaaga tagtcagcta ctgctgcaaa
      301 tacagcttca actgctgctg ctgagtcttt cttagtcaat tctgtagctt ctgctacttt
      361 agcgatcaaa tcttgtttgt ttgccatgtt aatgattcct ccaaataatt tctaattaac
      421 aaatataatc atatcctaaa atccctttta ggtcaagtta aaaacgctat ttcttcccat
      481 tttatttatt tttttaggag tggtaacgta tcaaaatagc ccaagcgttc tcacccgtgt
      541 gagtttgaat aatggaaccc gtttccaaaa cagaaattgg cttttcaaca taagcttgta
      601 agctttcttt catctctttt gcccaatcat cactaccaga atatgaaatt ccaatctctg
      661 ctacagcacg ttcagaaagc gatgttatca actcatctaa ccatttttta aatgttttag
      721 ttccacgacc tttaaccatt ggctgcaatt catggtcttt catttgcatg acaacacgga
      781 tattgagaag agagctcaac aagccagtta cacggctaat tcgtccacct ttgacaagat
      841 tttccaaagt tgaaacacca atataaagct ctgtatggtt tttaacctct tctacatgag
      901 ataaaattgc ctccatatct ttaccttctt gagctaactt cgcagcctca acaacttgga
      961 atttcagggc ttggtcagtg aaggaactat caacaacagt cacatctgca gtagataggc
     1021 tagcaccttg gcgtgctgct tctaccgtac ccgaaagagc atgggacata tgaatagcaa
     1081 gaatctggcc accatctttg cataggtctt caaaaatctc agcaaagaca cctacaggtg
     1141 gctgacttgt tttcggaaga ttcttacttt cttgcatcaa ctgaagaaat ttaccttctt
     1201 ctttcaaatc cgcatcagaa taaacaacat tatcaatcat tacagataat ggaacaattg
     1261 taatatctaa ttgctttact agttcaggtt caatagtaac agatgaatcg gttacaatct
     1321 taatttttgt catagtatca atctttctat tttaggattc agattggttt ccttacttct
     1381 aattatatca aaaaaaagat taaaaatcct aatggagtca atcaaatttt ccgtaaaatt
     1441 tgatataatc aacttataag aaaagaggtg tcctatgatt aaaaaaattt accccatttt
     1501 taccatttta ctaggtgctg ctatttatgc ttttggactg acttattttg tagttcccca
     1561 tcatctcttt gaaggagggg cgacaggcat taccctcatc accttttatc tttttaaaat
     1621 ccctgtttcc ctcatgaacc tgctgattaa tattcccctt ttcatcctag cttggaagat
     1681 ctttggagcc aaatccctct attctagttt actaggaacc ttagctttgt ccgcctggtt
     1741 agcttttttt gagcatattc cccttcatat tgatcttcaa ggtgatttac taatcacagc
     1801 ccttatagcg ggaatcctat tgggaattgg ccttggaatt atttttaatg ctggaggtac
     1861 aactggcgga actgatattc tagctcgtat tctcaacaaa tacactcata tatccatagg
     1921 aaaactgctc tttatcttag atttttgtat tctcatgttg attctcctaa tcttcaagga
     1981 tttgagattg gtttcctaca cgcttttgtt tgattttatt gtttctcgtg ttattgattt
     2041 gattggtgaa ggaggatatg ccggcaaagg ctttatgatt atcacaaaac gtcctgacca
     2101 acttgctaag gcgattaatg atgacctcgg aagaggtgtt acttttattt ctggtcaagg
     2161 ctactatagt aaagaaaatt tgaaaatcat ctactgtatt gtcggaagaa atgaaattgt
     2221 gaaaacgaag gaaatgattc atcgaatcga tcctcaagcc tttataacta ttacagaagc
     2281 ccatgaaatc ctaggagaag gcttcacctt tgaaaaagaa taaaaagagg taatgtcgtg
     2341 acctcaaaag ttagactaaa tcatctatct tttgggttac agacaacctc ttttttgttt
     2401 tatttactca agctcttaag accaattccg agttacttct tcatcagcct ttaactgatc
     2461 cactaattgg tcaactgagt caaatttggt catatcacga atgcgatcaa gccaataaac
     2521 catgacggtt tccccataaa tatcttgatt aaaatcaaaa atattgactt caaaacgtgc
     2581 ttcttctcca tcaaaggtca catttttccc gacactagcc atagcacgat acttctgtct
     2641 ttgaatctca acatcaacga cataaacgcc atctgctggc atataagtac ggtctaaaag
     2701 cactaaattc gctgtcggat aaccaattgt acgaccacga gcattaccat gaaccaccat
     2761 acctcttgat ggaagcggtg cccccaaaag ttttcctgct tctttcacat ttccatctaa
     2821 aatagcttga cggatacgag ttgaactaat ctttcctttc tcatcttcta caggtggaac
     2881 aatgataact tctccatcaa agtaatcctt taaatcttct gctgtttttt tgtcagaacc
     2941 aaatgtataa tcaaaacctg caacaataat tttggcattc atagccttga tataagttgc
     3001 aaagaattct tgtgcagtga gactagcgaa ttgactacta aaatcaagga gatataattc
     3061 ttctacacct tcgcgcttta attttctttc acgttcagca gggttcaaaa tatgcaaaaa
     3121 caaatctgga tgataaggct ctaaagcgat ctttggagat tcattaaagg tcataacgac
     3181 gataggcaat aaatcctttc tcgcagcctt gttggcaaca cgaaataatt cttgatgccc
     3241 cttatgtatg ccatcaaaat agccgagaac aacgactgaa tcagatggtg tgccaatatc
     3301 tttttggttt tttataggaa tagtaataat cataaaataa ttatatcata gcgatagcta
     3361 tttctggaac agaaaatctg aaatgttgtt tttttcacat gaagtgtacc tgttttcaaa
     3421 aagcacttta ttctatcgtt gcttaactat gaactttgca atattcttct caaaaacttg
     3481 taggacatct tcaaaatttt gcaaggagtg attagacttg ttcggtaacc ataaagtgtc
     3541 atactatgtt atgtatgaaa aagcaatgca actaactcct gagaacttta aattactaat
     3601 tggtgccaaa aaggtagaat ttagaatcga ggtacaccta tggctgtaaa atttacaaaa
     3661 tgagacaact tgggcaagat gtttgaagaa tttcctaaac tccctgattt gaagcaagtc
     3721 actttccctg atgacaaaga aaaaagccaa aacagcaaag aaaaactaga tgactgcttt
     3781 ccaacaactc ccatctagtg tgcttcagac tgggctattt ttctctccat ctgttagctt
     3841 ggattctcag accgtttcag ctaaagaata tcttttccct tatcagaagg aacggctcaa
     3901 accattcaga caagtgaagg gacgacaagc caatatttga aaccagatag cagttcttat
     3961 agtcaattga aataaaatct gaagaaatcg agtaggaaac tcatatcaat ttttaacagt
     4021 gttctattcc agattcatac tcaatgaaaa ttaaagtgca aactaggaag ttagccgcag
     4081 gctgtacttg agtacggcaa ggtgaaattg acgtggtttg aatttgattt tcgaagagta
     4141 tcaatccact atacatatta aaaagtatgg gtatcaaaat aaaaaaacag gctctccgaa
     4201 aactcggaaa gccttatttt aagctgtttc tagcttcctc acctttacat ttcaaggttc
     4261 gggataaaag gttcaatgaa cctttttatt ttgcgattgg gtaaacagaa acttgttttt
     4321 tatcgcgtcc tttacgttca aagcgtacta cgccttcaac tttagcgaac aaagtatcgt
     4381 ctccaccacg accaacgttt acacctggat agatgtgtgt accacgttga cggtaaagga
     4441 ttgatccacc tgttacagtt tgtccgtcag ctgctttagc tccaagacgt tttgcttgtg
     4501 aatcacgtcc gtttgatgta gaacctccac cttttttgtg ggcgaaaagt tgcaagttgt
     4561 taagagtcat ttttaacata atgttttcct ccgtgttagt tttctgtgat aactctggtt
     4621 tggacgaact cagaatagtt ctccgataag tttgccatac ctaagaaaaa tgattcaaag
     4681 aataactggg tcatttctct ctggtgtgaa ggaagatctt ttggtatttc aaccatcaga
     4741 tagccacctt catcttcgtt taattctagg attggttcat agcctgcaaa tttctcaata
     4801 gaattgataa agttaatggc aagcgtagaa accgatgcac acacgacatc taagccgtat
     4861 tcgccactct cggcgtgtcc agtaatttcc gcactcctca gctcgccatc ttcggctctc
     4921 tcaaagactg cctgtatcat gtgttctcct taaaattaag cgttgattgc gttgatgaca
     4981 acttttgtat atggttgacg gtgaccttgt ttacggtggc tacctttttt aggtttgtac
     5041 ttgtaagtaa ccactttctt ttgttttcct tgtttttcaa cagttccaac tacagtagct
     5101 ccagcaacaa gtggagttcc gacaacagtg ttttcaccac caacaagaac aacttcgtta
     5161 aaagtaactt cttgaccagc ttcaacgttc aatttttcaa cgtaaactgc ttgaccaact
     5221 tcaactttaa cttgttttcc gccagttttg ataattgcgt atgtgctcat tatgcacctc
     5281 ctatgatttt tatgggtttc cccgattttt tgtgaagact cgcctagcat cgtgggacga
     5341 accacttaaa cttgaataat caagcaacga tgtttgtgcg gttgcacagg atcgtgcata
     5401 gtcaactctt caagtatagc atatctccta ttttcttaca agtaataaca cctaaaatga
     5461 agctttttct tttacttttt tctgccaaga ggcaaaaagc atgctgaggt aaaaaacgct
     5521 catcataata ggaacaccaa gaatggtctt ttcatgatag aaaatcgtca aataggctga
     5581 aaagacaacg ccaaggacaa aactactaag caggctaaca aatatgaatc cttcacgcaa
     5641 aaaaggagtg tgcttggttc ggaaataatc tccaaaagcc agcatggtcc gtttgatatt
     5701 ccctgtcata aaagcgttat tataggcaat acccgacact tctccaaaag cagttgtcac
     5761 cagtcccata cagaaggcca agggcggcac tagatagata ttatccacag tttgcggcac
     5821 aaaagcaata atgattgata agattgccaa gggaatcaag gacagaatag gttttttcac
     5881 aattctcaat ttttccttat aaatcgttaa taaaaagact cccatcataa acgctagcaa
     5941 ggtgagaacc ttgtccctaa catccgaaac attattttta attaattcta ctgaaagaaa
     6001 gacaacattt ccagtttgtc cagctacaag ggtattcccg cgaacaataa aagtgtaagc
     6061 atccacatat ccagcacaaa acgtcaaaaa aagtgctaac cttttagact gacgtgatat
     6121 ttttcttata ggtaataacc tcattttacc tcccattgta ttttctctta gaaatattgt
     6181 accattttct ttctaaaaaa tcgtaggcta ccatttagat tttactatta gcataaaaat
     6241 aataatagac aactatttat ccaaaaatag atagatgtaa catgtttgca aacaaagcat
     6301 acgaaccttt agtaaaatca tttccatgaa actagaatag agccctctta gcaaaaatca
     6361 ttattttaat ttatttctaa tcactccttg acataaataa ctctcaccaa taaaagacta
     6421 tgtcttaaaa aaatggtata ataaaatcaa tacttgggct tgatggctat gctactaata
     6481 acaattagga gagaaaatca ggcacttgtt aacaacaagg attatcccct tgagatgaaa
     6541 ggaactttag aaatcttatg atgaacatgc aaaacatgat gcgtcaagca caaaaacttc
     6601 aaaaacaaat ggaacaaagc caagctgaac ttgctgctat gcaatttgtt ggcaaatctg
     6661 ctcaagatct tgtccaagcg accttaactg gcgataagaa agttgtcagc attgatttca
     6721 atccagctgt cgttgaccca gaggaccttg agactctttc tgatatgacc gttcaagcca
     6781 tcaactctgc tcttgaacaa atcgatgaaa ctaccaagaa aaaactgggt gctttcgctg
     6841 ggaaattacc tttctaaaaa caaggagcta gaacaatgct tgtcgataac aaaggctaag
     6901 aaaggtgcaa aaatg
//
LOCUS       DAVHTH010000079         6742 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.079, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000079 DAVHTH010000000
VERSION     DAVHTH010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6742)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6742)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6742
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.079"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            1..164
                     /locus_tag="VVR63_001907"
                     /pseudo
     CDS             1..164
                     /locus_tag="VVR63_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            331..531
                     /locus_tag="VVR63_001908"
     CDS             331..531
                     /locus_tag="VVR63_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000226586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6129882.1"
                     /translation="MVASASASSTSTQAQEQVDKSELRALSQELDQRLKALATVSDPK
                     IDATKAVLLDAQKAPEDSALTE"
     gene            573..978
                     /locus_tag="VVR63_001909"
                     /pseudo
     CDS             573..978
                     /locus_tag="VVR63_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377663.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1209..1916
                     /gene="ccdA2"
                     /locus_tag="VVR63_001910"
     CDS             1209..1916
                     /gene="ccdA2"
                     /locus_tag="VVR63_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004237834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEU6129883.1"
                     /translation="METIVFLISVFLAGVLSFFSPCIFPLLPVYAGILLDDQESAKSF
                     SLFGRKVLWSGLIRTLCFIAGISLIFFILGFGAGYFGHILYANWFRYGMGAIIIILGL
                     HQMEIFHLKKLEVQKSFTFKKSDSNRYWSAFLLGITFSFGWTPCIGPVLSSVLALAAS
                     GGNGAWQGAIYTLIYTLGMALPFLVLALASGLVMPYFSKIKRHMMLLKKIGGFLIVLM
                     GILLLLGQVNVLAGIFE"
     gene            1927..2484
                     /gene="sdbB"
                     /locus_tag="VVR63_001911"
     CDS             1927..2484
                     /gene="sdbB"
                     /locus_tag="VVR63_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     lipoprotein SdbB"
                     /protein_id="HEU6129884.1"
                     /translation="MKKVMFAGLSLLSLVVLMACGEEETKKTQAAQQPKQQTTVQQIA
                     VGKDAPNFTLQSMDGKEVKLSDFKGKKVYLKFWASWCGPCKKSMPELMELAAKPDRDF
                     EILTVIAPGIQGEKIVEQFPQWFQEQGYKDIPVLYDTKATTFQAYQIRSIPTEYLIDS
                     QGKIGKIQFGAISNADAEAAFKEMN"
     gene            2858..4249
                     /locus_tag="VVR63_001912"
     CDS             2858..4249
                     /locus_tag="VVR63_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001020339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEU6129885.1"
                     /translation="MNIFRTKNVSLDKTEMHRHLKLWDLILLGIGAMVGTGVFTITGT
                     AAATLAGPALVISIVISALCVGLSALFFAEFASRVPATGGAYSYLYAILGEFPAWLAG
                     WLTMMEFMTAISGVASGWAAYFKGLLSQYGIAFPQALNGTFNPQAGTFVDLLPILVLV
                     LVTSLVLLNAKAALRFNSILVILKFSALALFVLVGIWNIKFDNWSNFAPYGFGQIYGA
                     STGIMAGASLMFFGFLGFESISMAVDEVKTPQKNIPRGIVLSLSIVTILYALVTLVLT
                     GVVHYSHLNVDDAVAFALRSVGISWAANYVSLVAILTLITVCISMTYALSRMIYSLAR
                     DGLVPAAFKELTKTSKIPKNATILTGLASAVAAGMFPLASIAAFLNICTLAYLIMLAY
                     GLIRLRKEKGMPKAGEFKTPLVPLLPILSIIICLSFMLQYNMNTWIAFLVALLVGSII
                     YFTYGYKHSTIEE"
     gene            4392..5309
                     /gene="adcAII"
                     /locus_tag="VVR63_001913"
     CDS             4392..5309
                     /gene="adcAII"
                     /locus_tag="VVR63_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding lipoprotein AdcAII"
                     /protein_id="HEU6129886.1"
                     /translation="MKKQNLFLVLLSVFLLCLGACGQKESQTGKGMKIVTSFYPIYAM
                     VKEVSGDLNDVRMIQSSSGIHSFEPSANDIAAIYDADVFVYHSHTLESWAGSLDPNLK
                     KSKVKVLEASEGMTLERVPGLEDVEAGDGVDEKTLYDPHTWLDPEKAGEEAQIIADKL
                     SEVDSEHKETYQKNAQAFIKKAQELTKKFQPKFEKATQKTFVTQHTAFSYLAKRFGLN
                     QLGIAGISPEQEPSPRQLTEIQEFVKTYKVKTIFTESNASSKVAETLVKSTGVGLKTL
                     NPLESDPQNDKTYLENLEENMSILAEELK"
     gene            5317..>6742
                     /gene="phtD"
                     /locus_tag="VVR63_001914"
     CDS             5317..>6742
                     /gene="phtD"
                     /locus_tag="VVR63_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtD"
                     /protein_id="HEU6129887.1"
                     /translation="MKINKKYLAGSVAVLALSVCSYELGRHQAGQVKKESNRVSYIDG
                     DQAGQKAENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISE
                     ELLMKDPNYQLKDSDIVNEIKGGYVIKVDGKYYVYLKDAAHADNIRTKEEIKRQKQER
                     SHNHNSRADNAVAAARAQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKNEL
                     SASELAAAEAYWNGKQGSRPSSSSSYNANPAQPRLSENHNLTVTPTYHQNQGENISSL
                     LRELYAKPLSERHVESDGLIFDPAQITSRTARGVAVPHGNHYHFIPYEQMSELEKRIA
                     RIIPLRYRSNHWVPDSRPEQPSPQSTPEPSPSLQPAPNPQPAPSNPIDEKLVKEAVRK
                     VGDGYVFEKNGVSRYIPAKDLSAETAAGIDSKLAKQESLSHKLGAKKTDLPSSDREFY
                     NKTYDLLARIHQDLLDNKGRQVDFE"
BASE COUNT         2075 a         1243 c         1421 g         2003 t
ORIGIN      
        1 tatctggaag aagatatcag aggatttctt tggttgcagg tctaacaaat ggtgaattaa
       61 tcgctccaat gatttacgaa gagatgatga cgagcgactt ttttgaagta tggtttcaga
      121 agtttctctt accaacatta accacaccat cggttattat agtaaaatga aataagaaca
      181 ggacaaatcg atcaggacag taaaatcgaa ttctaacaat gttttagaag tccatatgta
      241 ctattctagt ttcaatatac cataactgtt cctagtcaac ctgcaagccc tgtcccagct
      301 ccaagctcag ctccgactca agatcctaga gtggtagcaa gcgcttcggc tagctcaacg
      361 agcacacaag ctcaagagca agttgacaag tctgaacttc gtgccttgag tcaagagtta
      421 gaccaacgct tgaaagcttt ggcaacagta tctgatccga aaatcgatgc aaccaaggct
      481 gtcctcctag atgctcaaaa agctccggaa gatagtgcct tgacagagta aggtctgcat
      541 actgcagtag agtctgtgaa ggctgggctg ccttggactc tctcaaagat gtgaaagcaa
      601 atgctagcga cagcaagcct acacaggaca agaaggatgc aaaacaagga acggaagata
      661 gtaaggattc agataagatg actgaaacaa actcagttcc agcaggagtg attgtggtca
      721 gtctacttgc cctcctaggc gtgattgcct tctggctaat tcgccgtaag aaagagtcag
      781 aaatccagca attaagcacg gaattgacca aggttctagg acagctagat gcagaaaaaa
      841 gcggataaaa aagtccttgc caaagcccaa aaccttctcc aagaaaccct tgatttcgtg
      901 aaagaagaaa atggctcagc agagacagaa actaaactag tagaggagct taaagcaatc
      961 cttgacaaac tcaagtaaaa catgatttat gaaatgtcag acctaaaaga cattttcgtt
     1021 cacaaaagca gcgacgagta atccttgtcg ttgctttttg gctattttgg gggataagat
     1081 ccgccttgac tagcaaaaga aaagattggt ccaatagtgc ccgatacgat tttgcgtagc
     1141 agaaagctta caaataaaat tgaatatagt aaaataggat tagaattatt aagaaagttg
     1201 gttctttatt ggaaacgata gtatttttaa tctctgtttt tctagcaggt gttttatcct
     1261 ttttttctcc ttgtattttt cctcttctgc cagtctatgc tgggatttta ttggatgatc
     1321 aagaaagtgc aaaaagcttt tctttgtttg ggagaaaggt tctctggtca ggcttgattc
     1381 gaacactttg ctttatcgct ggtatctctc tcattttctt tattctaggc tttggtgctg
     1441 gttactttgg tcatattctc tatgcaaatt ggtttcgata tggcatggga gctattatta
     1501 tcattttggg tcttcaccag atggaaattt ttcatttgaa gaaattagaa gttcaaaaaa
     1561 gttttacctt taaaaaatca gactctaatc gttattggtc agctttttta cttggtatta
     1621 cctttagctt tggttggaca ccttgtattg gtccagtttt aagttctgtt ttagcacttg
     1681 cggcttctgg aggcaatggc gcttggcaag gagcgattta tactctcatt tacactctgg
     1741 gcatggccct tcctttcttg gtattggcac tagcttcagg tctagtcatg ccatatttta
     1801 gtaaaatcaa gcgtcatatg atgctactaa agaaaattgg tggtttcctc attgttttaa
     1861 tgggaatttt gttactatta ggacaagtaa atgttctagc tggaattttt gaataaagga
     1921 ggacaaatga aaaaagtaat gtttgctggc ttaagtctct tgtcattagt tgtattgatg
     1981 gcctgtggtg aggaagaaac taaaaagact caagcagcac aacagccaaa acaacaaacg
     2041 actgtacaac aaattgctgt tggaaaagat gctccaaact tcacattgca atccatggat
     2101 ggcaaagaag ttaagttatc tgattttaag ggtaaaaagg tttacttgaa gttttgggct
     2161 tcatggtgtg gtccatgcaa gaaaagtatg ccagagttga tggaactagc ggcgaaacca
     2221 gatcgtgatt tcgaaattct tactgtcatt gcaccaggaa ttcaaggtga aaaaattgtt
     2281 gagcaattcc cacaatggtt ccaggaacaa ggatataagg atatcccagt tctttatgat
     2341 accaaagcaa ccaccttcca agcttatcaa attcgaagca ttcctacaga atatttaatt
     2401 gatagccaag gaaagattgg aaagattcaa tttggtgcta tcagtaatgc ggatgcagaa
     2461 gcagcattta aagaaatgaa ctagaatcga taaaatctga ttacaagatg tagtcagatt
     2521 ttggtaactt ctaaaactaa cttccagttt cccacaacct agcttttagt atgagaaaaa
     2581 cgcgtgacat cagtggaaat ccgtcttaga ctaacttcca ctggttttct ttttcttgat
     2641 atataagggt tcaaaagcga aaagactcag aaaaagtgca cgacaaatag ccctaaaaca
     2701 gagtcgtctt agagtaactt ccagttttgg gagagagatg gaagttactt tgagaagtta
     2761 cggtagtcag atttttttag aaaaacattt tataaatatt cacatatctc ctatatttat
     2821 ggtaaaatag aatcatcagt ttattttgga gtcaaagatg aatatattta gaacaaagaa
     2881 tgttagttta gataaaacag agatgcatag gcatttgaag ttatgggatt tgattttgct
     2941 gggtatcgga gccatggtag ggacaggcgt ctttacaatc acaggtactg cagctgcaac
     3001 acttgctggc ccagccctag tgatttcaat cgttatttct gccttgtgtg tgggattatc
     3061 agccctcttt tttgcagaat ttgcctcgcg agtacccgct acaggaggtg cctatagtta
     3121 cctctatgct atcttaggag aattccctgc ctggttggct ggttggttaa ccatgatgga
     3181 gttcatgaca gccatatcag gcgtagcttc gggttgggca gcttatttta aaggcttgct
     3241 ctctcaatac gggatagcct ttcctcaggc tttaaatggt acctttaatc ctcaagcagg
     3301 gacatttgtt gatttattgc ctattcttgt cttggtcttg gtgacttcgc ttgttttact
     3361 aaatgccaag gcagccttac gctttaattc gattctagtt attttgaaat tttccgcttt
     3421 agctctcttt gttttagtag gaatttggaa tattaagttt gataattgga gcaattttgc
     3481 tccttacggt tttggacaaa tctatggagc tagcactggt attatggctg gtgcgtcctt
     3541 gatgttcttc ggttttttgg gatttgaatc catctctatg gctgtagatg aagtcaagac
     3601 tcctcaaaaa aatattccta gagggattgt cttatcgctt tctatcgtaa ccattctcta
     3661 tgccttggtg acccttgttt tgactggtgt ggttcactat agtcatttaa atgtcgatga
     3721 tgccgttgcc tttgcccttc gtagtgttgg gattagttgg gcagccaact atgtgtcatt
     3781 agtggctatc ttgaccttga ttacagtttg tatttcgatg acctatgccc tatcgcgtat
     3841 gatttacagt ttagcacgtg acggcttagt gcctgctgcc tttaaggaac tgacgaagac
     3901 tagcaagata ccaaagaatg ctactatctt gacaggtcta gcttcagcag tagcagcagg
     3961 aatgttccca ctagccagta ttgcagcctt tttaaatatt tgtaccttag cctacttgat
     4021 catgttggct tatggtctga ttcgcttacg gaaagaaaaa ggaatgccca aagctgggga
     4081 atttaaaaca ccattggtac ctctgttacc aattttatcg atcatcattt gtttatcctt
     4141 catgttacag tataatatga atacctggat tgctttccta gttgcgttgt tagtaggaag
     4201 tattatttac ttcacttatg gctataagca ttctaccata gaagaataaa gtgaaagtct
     4261 attgagttgt tgacactcag cagattttta tatgtgaaag aaatttcaaa ttttttctaa
     4321 aaatatcttg acagattaaa ttttcaggag tagaatattt actagttaat taaatggtta
     4381 aggagttgtt catgaagaaa caaaatttat ttttagtcct gttaagtgtc tttcttttgt
     4441 gcttgggggc ttgtggtcaa aaggaaagtc agacaggaaa ggggatgaaa attgtgacca
     4501 gtttttatcc tatctacgct atggttaagg aagtatctgg tgacttgaat gatgttcgga
     4561 tgattcagtc aagtagtggt attcactcct ttgaaccttc ggcaaatgat atcgcagcca
     4621 tctatgatgc agatgtcttt gtttaccatt ctcatacact cgaatcttgg gcaggaagtc
     4681 tggatccaaa tctaaaaaaa tccaaagtga aggtcttaga ggcttctgag ggaatgacct
     4741 tggaacgtgt ccctggacta gaggatgtgg aagcagggga tggagttgat gaaaaaacgc
     4801 tctatgaccc tcacacatgg ctagatcctg aaaaagctgg agaagaagcc caaattatcg
     4861 ctgataaact ttcagaggtg gatagtgagc ataaagagac ttatcaaaaa aatgcgcaag
     4921 cctttatcaa aaaagctcag gaattgacta agaaattcca accaaaattt gaaaaagcga
     4981 ctcagaaaac atttgtaaca caacatacag ccttttctta tctagcgaag agatttgggc
     5041 ttaatcaact tggtattgca ggtatctctc ctgaacaaga accaagtcca cgacaactaa
     5101 cagaaattca ggaatttgtt aagacctata aggttaaaac gatttttaca gaaagtaacg
     5161 cttcttcaaa agtagctgaa actcttgtca aatcaacagg tgtgggtctt aaaactctga
     5221 atcctttaga gtcagaccca caaaatgaca agacctattt agaaaatctt gaagaaaata
     5281 tgagtattct agcagaagaa ttaaagtgag gaaagaatga aaatcaataa aaaatatcta
     5341 gcaggttcag tggcagtcct tgccctaagt gtttgttcct atgaacttgg tcgtcaccaa
     5401 gctggtcagg ttaagaaaga gtctaatcga gtttcttata tagatggtga tcaggctggt
     5461 caaaaggcag aaaatttgac accagatgaa gtcagtaaga gagaggggat caacgccgaa
     5521 caaattgtta tcaagattac ggatcaaggt tatgtgacct ctcatggaga ccattatcat
     5581 tactataatg gcaaggttcc ttatgatgcc atcatcagtg aagaacttct catgaaagat
     5641 ccgaattatc agttgaagga ttcagacatt gtcaatgaaa tcaagggtgg ctatgtgatt
     5701 aaggtagacg gaaaatacta tgtttacctt aaagatgcgg cccatgcgga caatattcgg
     5761 acaaaagaag agattaaacg tcagaagcag gaacgcagtc ataatcataa ctcaagagca
     5821 gataatgctg ttgctgcagc cagagcccag ggacgctaca ccacagatga tggttatatc
     5881 tttaatgctt ctgatatcat tgaggacacg ggtgatgctt atatcgttcc tcacggcgac
     5941 cattaccatt acattcctaa gaatgagtta tcagctagcg agttagctgc tgcagaagcc
     6001 tattggaatg ggaagcaggg atctcgtcct tcttcaagtt ctagttataa tgcaaatcca
     6061 gctcaaccaa gattgtcaga gaaccacaat ctgactgtca ctccaactta tcatcaaaat
     6121 caaggggaaa acatttcaag ccttttacgt gaattgtatg ctaaaccctt atcagaacgc
     6181 catgtggaat ctgatggcct tattttcgac ccagcgcaaa tcacaagtcg aaccgccaga
     6241 ggtgtagctg tccctcatgg taaccattac cactttatcc cttatgaaca aatgtctgaa
     6301 ttggaaaaac gaattgctcg tattattccc cttcgttatc gttcaaacca ttgggtacca
     6361 gattcaagac cagaacaacc aagtccacaa tcgactccgg aacctagtcc aagtctgcaa
     6421 cctgcaccaa atcctcaacc agctccaagc aatccaattg atgagaaatt ggtcaaagaa
     6481 gctgttcgaa aagtaggcga tggttatgtc tttgagaaga atggagtttc tcgttatatc
     6541 ccagccaagg atctttcagc agaaacagca gcaggcattg atagcaaact ggccaagcag
     6601 gaaagtttat cgcataagct aggagctaag aaaactgacc tcccatctag tgatagagaa
     6661 ttttacaata agacttatga cttactagca agaattcacc aagatttact tgataataaa
     6721 ggtcgacaag ttgattttga gg
//
LOCUS       DAVHTH010000080         6738 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.080, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000080 DAVHTH010000000
VERSION     DAVHTH010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6738)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6738)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6738
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.080"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            37..174
                     /locus_tag="VVR63_001915"
     CDS             37..174
                     /locus_tag="VVR63_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004264816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SapB/AmfS family lantipeptide"
                     /protein_id="HEU6129888.1"
                     /translation="MAEEVLNLQLVSVQVDETDEVDGMRFSTFSTNRCGNWSAFSWEN
                     C"
     gene            353..2962
                     /locus_tag="VVR63_001916"
     CDS             353..2962
                     /locus_tag="VVR63_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000386153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lanthionine synthetase"
                     /protein_id="HEU6129889.1"
                     /translation="MDYNFNLEHPFFFTNNDYSTDTSIKYQVSLPFNWHEVMNNDEWV
                     YQYPIGKFVERQGWKIHISSEYNSSHELLQDVAKICHEMRIPFKHLSTEDKFIMRNGK
                     LVSRGFSGKFITCYPNQNELESVLQRLESALKQYNGPYILSDKRWDEAPIYLRYGVFR
                     PSRDDEKKVAIDELIVGDEVVKDERLPVFKIPKGIVPPDFLNKWLDKKDKKQGDFPFI
                     IDNAIRFSNSGGIYNARLKEDGKKIILKEARPYTGLGFDGTYSSEKLASECKALKILN
                     EWSETPKIYWHGKIWEHTFLGIEHMKGVPLNRWVTNNFPLYEVVDKTKDYLLRVSKIV
                     EKLIDLTNKFHSENVYHQDLHLGNILVKDEDEISIIDWEQAVFSNDEKVVHKVAAPGF
                     RAWRETLPSEIDWYGIRQIAHYLYMPLVTTSDLTYNYVSQTRIEGKKLFESLGYTREH
                     IDYVESLLSYLDSKCPQIENISRKKVLKSMHEIRTIESEQDIQDFIIKLLRGFTLTYG
                     QWRKEFQSRFFPVHYYGLNFNQGIAFSDLAILWSYQQLAKKVKNFKFDDYYEIRTQVI
                     NEAVNNFKKSSLSGLFDGKIGTIWLIYEFGEIDRAVELFTTHFIEIFENSQNKNLYSG
                     QAGILLVGLYFLSKGEIDNKLGEEILIRLREYTLNYIENPETFCKVGASDVQSNDPYE
                     NFGGLLYGHAGVAWLFGEAYKLTGESIYKNGLELAVDKELVAYKVDSNNSLQYSQCHR
                     LLPYLATGSAGLLLLINRNKEILSSKYLKYLTSLERATDVVFCVLPGLFNGFCGLEVA
                     NNIYSDIDDNFSGQKKLIEQLYRYLCVIEEGFVIAGDNGLKITTDIASGFAGVAIGLV
                     SIMDNKLTILPQI"
     gene            2995..4935
                     /locus_tag="VVR63_001917"
     CDS             2995..4935
                     /locus_tag="VVR63_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S9 family peptidase"
                     /protein_id="HEU6129890.1"
                     /translation="MNQSNEIFLNTIQEKTHYKRSISSSFQELKKWNSLIFRRGRYWY
                     QFDNWSIPNTGVIKEWYVEDNDWIPKVSSSSLDNSNSLKIVFDVEKYTLPDDSILQDV
                     RISSDESYIVLVVSSLRSTNLIGIKKYTMEELFIIEDISVESSFYLGKFGVMYTRSKE
                     YGRPSKLFYKSFDSFTEEELFEENECSFRLKIVHIDSNNCFVKSVDFQKGRIFLYSFD
                     RTGFVRHSYTETVAPTPRDIALFSTEKAQYFLGISSTEEKKDQLILRETSSGDRVSIT
                     IPYQDRARRVHCIGRYILLDCSNAANSVFYLATFKNNSLRELSVNKITFDEKTTLYEN
                     SFSDRVLLFLERRTFYEKILSFDLIENTLKTEFERPIIKSNNTKYFSKVIWTKKDSYD
                     VSIPISLFWKSEDTDELPRRKKCILSVYGAYGKNDNSDLDEIMLSIIDAGFIYAIVHV
                     RGGGYLGGEWYRSGKALNKWNSIRDFIEGVNYLRENDVIDSKRLGLITSSAGGIIAGA
                     VLNEEKNLLQSILLFSPFINPYDTLQNPNDPLSKTEIAEWGDIRAPEVKAYIKSYSPM
                     QNIEKARDSNTVIVNILGEKDPYINNNEVIEWSKKLNSIGVKSLLYLNKAADHGGFTP
                     SDVLLMIDTLNYFFEEVGRNNL"
     gene            4932..6539
                     /locus_tag="VVR63_001918"
     CDS             4932..6539
                     /locus_tag="VVR63_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6129891.1"
                     /translation="MNYLKFIKKTKLILMGILIFLSSFNGVLLSGIIVYAGSLNQTSS
                     FSDVLRFGAISILGWSAIYISNYYLEVTEASITKDINVKIKQGYFREQYLSSEMVKDY
                     SSIISVLSNDLRLIEENYFRQIFEIISSILLFIVSLSFMLYLNFLVSIIFIVLSALPI
                     IVPVFMKKMLSNSANEYSNSNAEYTHIIKEIFNGFKTLKSYSVTKEIISLSDKKLDKL
                     EDSTFNLKRSEVLSKLVAVLISGFCFLVPLVVGCYFVIYHKSLSFSELIGIFLANDKV
                     LGPIQSIAYSLNKINTTKDLRKPFLKYLSGEKNFIDAEHDNNGLYTSSIDEIHMKDVV
                     YSITPENKLSIDFSFKSPFRVLLTGTSGSGKTTILNLINGSLKPQKGYVNLLSHGKKS
                     SDSIPTVDQTPYIFDTTIRENVTLFQNEYFSDDQIIEVLKKVNLYEELEKIDILNYQC
                     GENGSNLSGGQKQKIALARALIRNNKVYLFDEISANLDNDNSNSIHDILFNLGISFIE
                     VSHHYDLNDKRYTDIYKLENGTLFKIK"
     gene            6554..>6738
                     /locus_tag="VVR63_001919"
     CDS             6554..>6738
                     /locus_tag="VVR63_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000356590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU6129892.1"
                     /translation="MDKDYILKVKGLYHQFLLGNNKTLQVLKNVSLSASRGEFISILG
                     ISGSGKSTLLKCISSLL"
BASE COUNT         2375 a          823 c         1283 g         2257 t
ORIGIN      
        1 acttaatccc aaaaatttaa ataggaggag ctagctatgg cagaagaagt attaaatctt
       61 caattagtat ctgttcaagt tgacgaaaca gatgaagttg atggaatgcg atttagtaca
      121 ttcagtacaa atcgttgcgg taactggagt gcttttagtt gggaaaattg ttaattcatt
      181 taaattgtaa actttagaga ttctctggag ttatggatgt cgttccaata tgtgcacgtt
      241 ggaatgttag tgcttatatg gggagaatcc aaaggattct ccctttttat ttaaataagt
      301 ctgtctagct atagatatat taagtttgat aaaatttctt ggagattttg ttatggatta
      361 taatttcaat ttggagcatc ctttcttttt cactaataat gattatagta cagatactag
      421 cataaagtac caagtaagtc tgccttttaa ttggcacgaa gtaatgaata atgatgagtg
      481 ggtttatcaa taccctattg gaaaatttgt tgaaagacaa gggtggaaaa tacacattag
      541 ttcagagtat aacagttcac atgaattgtt acaagatgta gcaaaaattt gccatgaaat
      601 gcgaattcca tttaaacatc ttagtacaga agacaaattt atcatgcgaa acgggaaatt
      661 ggttagtcga ggattttctg gtaaatttat tacatgttat ccaaatcaaa atgaattaga
      721 gtcggttttg caaaggttag aaagtgcctt aaagcaatat aatgggccat atattttaag
      781 cgataaacgt tgggatgaag caccaatata tctgaggtat ggtgtgttta ggccgtcaag
      841 ggatgatgaa aagaaggttg ctattgatga attaattgtt ggcgatgaag ttgttaaaga
      901 tgaacgttta ccagtattta aaattccaaa aggtatagtg ccccctgact ttttgaataa
      961 atggcttgac aagaaagata aaaaacaggg agactttccc tttattatag ataatgcaat
     1021 tagattttca aacagtggtg ggatatataa tgctaggcta aaagaagatg ggaaaaaaat
     1081 aattttaaaa gaggctagac cgtatacagg tctaggattt gatggtactt attcttcaga
     1141 gaaattagct tcggagtgca aagcactaaa aattctaaat gaatggagtg agacgcctaa
     1201 aatatactgg cacggtaaga tctgggagca caccttctta ggaattgaac atatgaaggg
     1261 cgttccacta aatagatggg ttaccaataa ttttccttta tatgaagttg ttgataagac
     1321 caaagattat ctattgagag tttcaaagat agtagaaaaa ctcatcgatt taacgaataa
     1381 gtttcattct gaaaatgtat atcatcaaga tttacattta ggaaatatct tggttaagga
     1441 tgaagatgag attagtataa tagactggga acaggctgtc ttttcaaatg atgaaaaagt
     1501 tgtacataaa gttgcagccc ctggttttag agcatggcga gaaacacttc ccagtgagat
     1561 agattggtat ggtattagac aaatagctca ttatttatac atgccactag taactacatc
     1621 ggatttgaca tacaactatg taagtcaaac caggatagaa ggaaaaaaac tatttgagtc
     1681 tttgggttat acaagagaac atatagatta tgtagaaagt ttattgtcat atctagattc
     1741 taaatgtcca cagattgaga atatttccag gaaaaaagtt ttaaaatcca tgcatgagat
     1801 tagaactatc gagagtgagc aagatataca agattttatt ataaaattat tgagagggtt
     1861 tacgctaact tatggacagt ggcgtaaaga atttcaatca agattcttcc cagttcatta
     1921 ttatggtctg aattttaatc aaggaattgc gttttcagat ttagctatcc tttggagtta
     1981 tcaacaacta gctaagaaag taaaaaattt caagtttgat gactattatg agattcgaac
     2041 acaggttatt aatgaggcag taaataattt taagaaatcg tccctttctg gtctttttga
     2101 tggtaaaatt ggtacaatct ggctcattta tgaatttggg gagatagatc gggcagttga
     2161 actttttaca actcatttta tagagatatt tgagaattca caaaataaaa atttatatag
     2221 tgggcaggct ggaattttac tggttggact gtattttctt agtaaagggg aaattgataa
     2281 taaactagga gaagaaatac taattaggct tagagaatat actttaaatt atatagaaaa
     2341 tccagaaact ttttgtaaag ttggcgctag tgatgttcag agtaatgatc cttatgagaa
     2401 ttttggtgga ttactatatg gtcacgcagg ggtagcttgg ctcttcggtg aagcttataa
     2461 attaactggt gaaagtatct ataaaaatgg tctagaattg gctgtagata aagaattagt
     2521 tgcttataaa gtagatagta ataattcatt gcagtacagc caatgtcata gattactacc
     2581 atatctagca actggaagtg ctggcctgct tttacttatt aatagaaata aagaaatctt
     2641 gtcaagcaaa tacttaaaat atttaacttc tttagagagg gcaactgatg tagttttttg
     2701 tgtattacca ggtttattta acggattttg tggtcttgaa gttgctaata atatatatag
     2761 tgatatcgat gataactttt caggacaaaa gaaattaatt gaacaacttt atagatattt
     2821 gtgtgtaatt gaagaaggat ttgttattgc gggagataat ggtttaaaga taacaacaga
     2881 tattgcttcg ggatttgcgg gtgttgcaat tggattggta tcaataatgg ataataaatt
     2941 gacgattctt cctcaaatat aatatttaga taccattatt aaggggtcat acttgtgaat
     3001 cagagtaatg aaatattttt aaatacaata caggaaaaaa cacactataa gaggtctatc
     3061 tcttcatcat ttcaggaatt aaaaaaatgg aattctttga tatttaggag agggcgatat
     3121 tggtaccaat ttgataattg gagtataccc aatactggtg taataaagga atggtatgtc
     3181 gaagataatg actggattcc taaggttagt tcttccagtt tagacaattc aaattcactt
     3241 aaaattgtct ttgatgtgga aaaatatact ttgccagatg atagtatctt acaggatgtt
     3301 aggatttcat ctgatgagag ttatatagtt ttggttgtat cctcactgcg tagcactaat
     3361 ttaattggaa taaaaaaata tactatggaa gagttattta tcattgaaga tatttcagta
     3421 gaaagttcgt tctatttggg taaattcggt gttatgtata ctcgctccaa agagtacggg
     3481 aggccaagta agttattcta taaatctttt gatagcttta cagaagagga actgtttgaa
     3541 gaaaacgaat gctcttttcg attaaaaata gtccacattg atagcaataa ttgttttgta
     3601 aagtcagtag actttcagaa aggcaggatt tttctataca gtttcgaccg gacgggtttt
     3661 gttagacact cttacacaga aacggtagcc ccaacaccta gagatatcgc tctatttagt
     3721 acagaaaaag cacagtactt tcttgggatc tcttcaactg aagaaaagaa agatcaacta
     3781 attctaaggg aaacttcttc gggagacaga gtttctatta ctataccata tcaagatagg
     3841 gctagaagag ttcactgtat aggacgttat atccttttag actgttcaaa cgcagcgaat
     3901 tccgtctttt atcttgctac atttaaaaat aatagtttga gggagttgag tgttaataag
     3961 ataacatttg atgaaaagac aacactttat gaaaattcat tttctgatcg tgttcttctg
     4021 tttttagaga ggagaacttt ttacgaaaaa atacttagtt ttgatttaat agaaaataca
     4081 ttaaaaactg aatttgaaag acccatcata aaatcgaata atactaaata tttttctaag
     4141 gtgatttgga ctaaaaaaga cagttatgat gtaagcatac cgatttcttt attttggaaa
     4201 agtgaagata cggatgagct cccaagaaga aaaaaatgta ttctaagtgt ctatggggct
     4261 tatggtaaga atgataattc tgatttagat gaaattatgt tatctataat agatgcaggt
     4321 tttatttatg ctatagttca tgtaagaggt ggaggctatt tgggtggtga atggtatcgc
     4381 tcaggaaagg cgttaaacaa atggaattct atcagagatt ttattgaggg agtaaattat
     4441 ttaagggaaa atgatgtaat tgacagtaag cgattaggtt taataacttc tagtgcaggt
     4501 ggaataattg ctggtgcggt gttgaacgag gaaaaaaatt tattgcaaag cattctctta
     4561 ttttcgccat ttataaatcc ttatgataca cttcagaatc caaatgatcc tctttctaag
     4621 accgaaatag cagagtgggg agatattaga gcccctgaag taaaggctta tataaagtca
     4681 tattcgccta tgcaaaatat tgaaaaggca cgagactcaa atactgttat agttaatatt
     4741 ttgggtgaga aagacccata tattaataat aacgaagtga tagagtggtc aaagaaatta
     4801 aattctattg gagttaaaag tttgttgtat ttaaacaaag cagctgatca tggaggtttt
     4861 actccatcag atgttctctt aatgattgat actttaaatt atttctttga agaagtggga
     4921 aggaataact tatgaattat ttaaaattta taaaaaagac taaacttata ttaatgggga
     4981 ttttaatatt tctatcttcg tttaatggtg tcttgctctc aggaattatt gtatatgcag
     5041 gtagtttaaa tcagacttcc tcattttctg acgttctaag atttggtgct ataagtattc
     5101 tgggttggtc agcaatctat atatcaaatt actatttaga agtaacggaa gcatcaataa
     5161 cgaaagatat aaatgtaaaa attaaacaag gatattttag agaacagtat ctttcttctg
     5221 aaatggttaa agattactca tctattattt cagttttgtc aaatgatttg agattaatcg
     5281 aagaaaacta ttttagacaa atttttgaaa taatttcttc aatattgttg ttcatcgtct
     5341 ctctaagttt tatgctttat ttaaacttcc tagtttcaat aatatttatt gtattatcag
     5401 cattgccgat tatagtacct gtctttatga agaagatgtt gtctaattca gctaatgagt
     5461 actctaacag caatgcagag tatactcaca taataaaaga aatttttaat ggttttaaga
     5521 cattaaaatc ttattctgtt actaaagaaa taattagttt gtcggataaa aagttggata
     5581 aactagaaga ttctactttt aatttgaaac gatcagaggt tctttcaaaa ttggttgcag
     5641 tactaatttc aggtttttgc tttctagttc ccttggttgt aggatgttat tttgtaattt
     5701 atcataaaag cctttctttt agtgaactga taggtatttt cttagcaaac gataaagttt
     5761 tagggccgat acaatcaatt gcctattcat taaataagat aaatacaacc aaagatttaa
     5821 ggaaaccgtt tttaaaatac ttaagtggag agaagaattt tatagacgct gaacatgata
     5881 ataacggact gtatacttca tcaatagatg agatacacat gaaagatgtt gtatattcta
     5941 ttacaccaga aaataaatta agtattgact tctcatttaa gtcaccattt agggtattat
     6001 taacaggaac ttctggtagt gggaaaacaa cgattttaaa tttaattaat ggttctttaa
     6061 agccacaaaa aggttatgta aatttgttat cacatgggaa aaagagttca gattcaatac
     6121 caacagttga tcagacacca tatatttttg acactactat tcgtgagaac gtaactttat
     6181 ttcaaaatga atatttttca gatgatcaga taattgaggt gttaaaaaag gtaaatctat
     6241 atgaagaatt agaaaagata gatatactaa attatcaatg tggtgaaaat ggtagtaatt
     6301 tgtctggagg tcaaaaacaa aaaatagctt tagctagagc tctgattaga aataataaag
     6361 tgtacttatt tgacgaaata tcagctaatt tagataatga taattcaaat tccatacatg
     6421 atattctgtt caatttaggt atttcattta ttgaagtttc acatcattat gacttaaatg
     6481 acaagagata cactgatata tataaattgg aaaatggaac acttttcaaa attaagtgat
     6541 tggaggcaag aatatggata aagattatat attaaaagtg aaagggctgt atcatcaatt
     6601 tttactagga aataataaaa cgttgcaagt gctgaaaaat gtttctcttt ctgcttcgag
     6661 aggagaattt ataagtattc taggaattag tggttctgga aagtcaactt tattaaaatg
     6721 tatttctagt ttgcttga
//
LOCUS       DAVHTH010000081         6704 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.081, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000081 DAVHTH010000000
VERSION     DAVHTH010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6704)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6704)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6704
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.081"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            complement(43..159)
                     /locus_tag="VVR63_001920"
     CDS             complement(43..159)
                     /locus_tag="VVR63_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000233180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HEU6129893.1"
                     /translation="MVGVFRQQALYPATATSHYPSKSTAGLQELVRGGQENV"
     gene            complement(374..727)
                     /locus_tag="VVR63_001921"
     CDS             complement(374..727)
                     /locus_tag="VVR63_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HEU6129894.1"
                     /translation="MTVRHPGISPTNDLVAKKIFSNPEITCQFIRDMLDLPAQNVTIL
                     EGSNIHVLLSMPYSVQDFYTSIDVLAELDNGTQVIIEIQVHHQNFFINHLWAYLCSQV
                     NQNLEKIRQREGDTH"
     gene            complement(845..1813)
                     /locus_tag="VVR63_001922"
     CDS             complement(845..1813)
                     /locus_tag="VVR63_001922"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEU6129895.1"
                     /translation="MSFSDLKLFALSSNKELAERVAQEIGIELGKSSVRQFSDGEIQV
                     NIEESIRGKHVFILQSTSSPVNDNLLEILIMVDALKRASAESVNVVMPYYGYARQDRK
                     ARAREPITSKLVANMLEVAGVDRLLTIDLHAAQIQGFFDIPVDHLMGAPLIADYFERR
                     GMVGSDYVVVSPDHGGVTRARKLAEFLKTSIAIIDKRRSVDKMNTSEVMNIIGKVEGK
                     TCILIDDMIDTAGTICHAADALAEAGAVEVYASCTHPVLSGPATDNIQKSAIKKLVVL
                     DTIYLPEERLIDKIEQISIAHLLGDAIVRIHEKRPLSPLFDIEKKI"
     gene            complement(1958..2741)
                     /locus_tag="VVR63_001923"
                     /pseudo
     CDS             complement(1958..2741)
                     /locus_tag="VVR63_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749763.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
     gene            complement(2766..3263)
                     /locus_tag="VVR63_001924"
     CDS             complement(2766..3263)
                     /locus_tag="VVR63_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HEU6129896.1"
                     /translation="MSYFEQFMQANQAYVALHGQLNLPLKPKTRVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFENEPF
                     QEYLKEELGVDVSDQDFLPFQDIEESVREDMQLLIESPLIPDDVIISGAIYNVDTGSM
                     TVVEL"
     gene            complement(3336..4697)
                     /gene="radA"
                     /locus_tag="VVR63_001925"
     CDS             complement(3336..4697)
                     /gene="radA"
                     /locus_tag="VVR63_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000336571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HEU6129897.1"
                     /translation="MAKKKATFVCQNCGYNSPKYLGRCPNCGSWSSFVEEVEVAEVKN
                     ARVSLTGEKTKPMKLAEVTSINVNRTKTEMEEFNRVLGGGVVPGSLVLIGGDPGIGKS
                     TLLLQVSTQLSQVGTVLYVSGEESAQQIKLRAERLGDIDSEFYLYAETNMQSVRAEVE
                     RIQPDFLIIDSIQTIMSPEISGVQGSVSQVREVTAELMQLAKTNNIAIFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNP
                     SQVFLEERLDGATGSSIVVTMEGTRPILAEVQALVTPTMFGNAKRTTTGLDFNRASLI
                     MAVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKDKPTNPQECFVGE
                     LGLTGEIRRVNRIEQRINEAAKLGFTKIYVPQNSLTGITLPKEIQVIGVTTIQEVLKK
                     VFA"
     gene            complement(4711..5226)
                     /locus_tag="VVR63_001926"
     CDS             complement(4711..5226)
                     /locus_tag="VVR63_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEU6129898.1"
                     /translation="MKIIFVRHGEPDYRELEERSYIGFGIDLAPLSEMGRQQVQKLSK
                     NPLLSSAEIIVSSAVTRALETASYVVCATGLPLRVEPLLHEWQVYKTGIENFETARRL
                     FLENKGELLPNSPIQYETATEMKSRFLECMSKYREHQTVVVVAHRMLMRQFVPNEKID
                     FCQVIECELEI"
     gene            complement(5228..5671)
                     /locus_tag="VVR63_001927"
     CDS             complement(5228..5671)
                     /locus_tag="VVR63_001927"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HEU6129899.1"
                     /translation="MKIRGFELVSSFTDENLLPKRETAHAAGYDLKVAVRTVVAPGEI
                     VLVPTGVKAYMQPTEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPGNEGHIFAQM
                     KNITDQEVVLEVGERIVQAVFATFLIADGDAADGVRTGGFGSTGH"
     gene            5976..6125
                     /locus_tag="VVR63_001928"
     CDS             5976..6125
                     /locus_tag="VVR63_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6129900.1"
                     /translation="MNKEDWLRLLEKAIDNIPETVTAIASLVTAITVARQNKKRKPKS
                     RQRKR"
     gene            6267..6446
                     /locus_tag="VVR63_001929"
     CDS             6267..6446
                     /locus_tag="VVR63_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6129901.1"
                     /translation="MREVIQELLDSSMSTSAISQGAGVPWTTVSDLRKGKTSMDKMAL
                     LTAEKLYEFATTDKQ"
BASE COUNT         2080 a         1568 c         1201 g         1855 t
ORIGIN      
        1 tcctgtgcta acaagacttg ttcttctcgc atatgtagtt gactaaacat tttcctgtcc
       61 tcctcggacc agctcttgta gtccagcagt tgatttgctt gggtaatggc tcgttgcggt
      121 tgctgggtaa agggcttgtt gccgaaaaac tccaaccatg gcttgcgaac cttgtctttg
      181 ctggtttctc tgtatttttt aattccaaga atgccatctt aaccagatgg ttttcctgtc
      241 cattgttggt aatcgccaat acctcacctg ttgtgtcttc gcgcatacta acgctatgaa
      301 aagccaggcc atctgagaaa taattgctat ccacgatagc aatgacgtaa acaggagcga
      361 tgtgtttgta gatctagtga gtatcacctt ctcgctgacg aattttttca agattttgat
      421 taacctgact gcacaggtaa gcccacaagt gattgatgaa aaaattctga tgatggactt
      481 gaatctcaat aattacttga gtaccgttat ccaactccgc caagacgtct atactggtat
      541 aaaaatcctg caccgagtaa ggcatggaga gtaatacgtg aatattgcta ccctccaaaa
      601 tggtcacatt ttgggctggc aaatccagca tatcgcgaat aaattgacaa gtaatttctg
      661 gattgctaaa gattttctta gctaccaagt cattggttgg gctaatgccc ggatgacgta
      721 cagtcatatt tcttctcttt ttattatatc acagttttaa atctagcttt actagattca
      781 ccgctactat ctatttattc ggaaaaaaga cgaaaaaacc tgagaatcat ctcaggcttg
      841 gtcattaaat ttttttctca atatcgaaaa gtggagaaag tggtcgtttt tcatgaatac
      901 gtacgatagc atcccctagg agatgagcga ttgaaatctg ctcaatctta tcaatcaaac
      961 gctcttctgg cagatagatg gtatccaaaa caaccaattt cttaatagct gatttttgga
     1021 tattgtccgt agcaggacca gaaagaactg ggtgcgtaca gcttgcatag acttcaacag
     1081 caccagcttc cgcaagagca tctgccgcat gacaaatcgt tccagcggta tcaatcatat
     1141 catcaatcaa gatacaagtc ttgccttcaa ccttaccgat gatgttcata acttcactag
     1201 tattcatctt atcaacgcta cgacgtttat caataatagc gatagatgtt ttcaaaaatt
     1261 ctgccaactt acgagcacga gtcacccctc catggtccgg gctgacaacc acatagtcag
     1321 aaccaaccat accacgccgc tcaaaataat ctgcaattag aggagcaccc atcaaatgat
     1381 ccacaggaat atcaaagaat ccttgaattt gcgcagcatg caagtcgatg gtcaataaac
     1441 gatccactcc agctacttca agcatatttg cgacaagttt tgaagtgatt ggctcacgcg
     1501 ctctcgcctt tctatcctga cgtgcatacc catagtaagg catgacaaca ttgacagact
     1561 ctgcactcgc acgcttcaaa gcatctacca taatcaaaat ttcaagcaga ttgtcattta
     1621 caggcgaact agttgattgt aagataaaga cgtgtttccc acggattgat tcttcaatgt
     1681 tgacctgaat ctctccatct gaaaattggc gaacacttga tttccccaac tctatcccaa
     1741 tctcctgcgc cacacgttct gccaattctt tattagaaga aagggcaaac agctttaaat
     1801 cagaaaaaga catgatttcc tccggtatat atgtatcgct tgtgcttttc acaagatttt
     1861 ccatctacca ttgtagcgct ttttgcacta tttttcaatc aaaaataaaa gaagggcacc
     1921 atatttgtac ccttgcatca ttcttttgaa aaatattcta ggtcatcaac tcattgtgtt
     1981 tctcaacaaa gcaataagca tgataataac catagagagc aatagccgta accactggaa
     2041 tcgctaaagg caactctgtt tccaactcca caaaaggaga gttaaacaat aagaccctgt
     2101 ttcttgccaa ccttctgtcc tttataggct ctgtaaagca agtaaacacc tactacagct
     2161 agacctgaaa aagtccagtg agaggcaatt cctgagatga tacgctctaa aattcgcgaa
     2221 atagtaaagt caaagccctc tggcaaatcc gtacgaatat aaccaatatc ctcaatcatt
     2281 tggaatccca aaccggaggc aattccaagt aaaaacaaaa attttaattt tcgcacagga
     2341 atcaaagcca aaacaaaaac aagtggcaat aatttcaagg gttcttctac caaaggagcc
     2401 acaatagcac tttcaaaggc atttaaaaat ggactatctg ggaaaagaac ccccagtaaa
     2461 tcatgtatat aagtattagc aaaactagac aaccagcctg aaaggaacat ccctcccaat
     2521 aaagacagaa tcaaaacctt ctttggcaat tcccattttt tcccaatacg gaagagaaaa
     2581 taaagagccg gaatcatgta aaagagagct agaaagatag aaactcccat tagtccatat
     2641 tccgcacctg acctcgaacc gtccgtatag tagatggttt catactgtaa accaatacat
     2701 agcaataaaa taaaaataaa taaaatactg cttttcttca tacactttct ttctaaatga
     2761 agtatttata attctacgac tgtcatactt cctgtatcaa cattgtaaat agcaccagag
     2821 ataatgacat cgtctggtat taggggagac tcgataagca gttgcatatc ctcgcgtaca
     2881 ctctcttcta tatcttggaa gggcaagaag tcctggtctg acacatctac acctaattcc
     2941 tcttttaaat actcctgaaa aggttcattt tcaaaggtct gagcaccaca gtctgtatgg
     3001 tgcaatacca caatctctct tgtccccatt tgttgctggg aaataactag cgaacgaatc
     3061 atgtcttcag tcactcgacc acctgcattc cgcaagatat gagcatcccc aagtgccaag
     3121 cccagagctt gcgcaacgtg caaacgtgag tccatacagg tcacaatggc tactctggtt
     3181 ttaggtttaa gtggcagatt taactgccca tgtagggcaa cataagcctg attggcttgc
     3241 ataaactgtt caaaatacga cacgattccc tccttgaaaa tttgatagtc aaatatttct
     3301 cctatcttat catttttaag agaatttgtc acggattatg caaagacctt tttcaagact
     3361 tcctgaatcg ttgtcacgcc aatgacctga atttccttag gcagagtgat tcctgtcaag
     3421 gaattctgag gtacataaat cttagtaaag cccagtttag cagcttcgtt gatgcgttgc
     3481 tcaatacgat tcacgcgccg aatctctcct gtcaagccca gttctccgac aaaacattcc
     3541 tgaggattag ttggcttgtc tttgtagctc gaagcaatag caactgcaac agccaagtca
     3601 atggcaggtt catccaattt aacaccacca gcagatttga gataggcatc ctgattttgc
     3661 aagagaagcc ctgcccgttt ttccaaaaca gccataatca agctagcacg gttaaaatca
     3721 agtcctgtcg tagtacgctt ggcatttcca aacatggtcg gtgttaccaa agcctgaacc
     3781 tccgccaaaa tcggacgcgt cccttccatg gttacaacga tggaggaacc agtcgcccca
     3841 tccaaacgct cttctaggaa aacttgactc ggattgagta cctcaaccaa gccgcccgac
     3901 tgcatctcaa aaatcccaat ctcattagtg gaaccaaaac gatttttgac cgctctcaaa
     3961 atacgaaagg tgtggtgacg ctccccttca aagtaaagca ccgtatccac catatgctcc
     4021 aacatacgag gcccagccaa ggttccttct ttggtcacat gacctacgat aaagatggca
     4081 atgttattgg tcttggccaa ctgcatgagt tcagcggtca cttcacgtac ctgagaaaca
     4141 gacccctgca cccctgaaat ctcaggagac atgatggtct ggatggaatc aataatgaga
     4201 aagtctggct ggatacgctc cacttctgca cgaacactct gcatattggt ctctgcatag
     4261 agataaaact cactatcaat atcacctaag cgctctgcac gtagtttaat ctgctgggca
     4321 gactcctccc cactgacata gagaactgtc cccacttggg acaactgggt tgagacttgt
     4381 aggagaagag ttgatttccc aatcccagga tccccaccga tgaggacgag acttcctggt
     4441 accactccgc ctccaagcac acggttgaat tcctccatct ccgtcttggt tcgattgaca
     4501 ttgatggaag tcacctcagc tagtttcatg ggcttggttt tctcacctgt caaggacaca
     4561 cgcgcattct tgacctcggc aacctcaacc tcttccacaa aagaagacca agacccacag
     4621 ttggggcaac gtcccagata tttaggggaa ttatacccac aattttgaca tacaaatgtc
     4681 gcttttttct ttgcgatgac aaacctcttt ctatatctct aactcacact caatcacttg
     4741 gcaaaaatca atcttctcat ttggcacaaa ctggcgcatg agcattcgat gagcaacaac
     4801 taccacagtc tgatgttctc gatacttaga catacattct agaaaccgag acttcatttc
     4861 cgtagctgtc tcatattgaa taggactatt aggaagcaac tcccccttgt tttctaaaaa
     4921 cagtcttcta gctgtttcaa agttttctat tcctgtttta tagacctgcc attcatgtaa
     4981 taaaggctct actcttaaag gaagacccgt agcacagacc acatacgaag ccgtttctaa
     5041 agctcttgtg actgcagaag atacgattat ttcagctgac gagagtaaag gatttttgct
     5101 caatttctgg acttgctgcc gtcccatctc agacaagggt gccaaatcta tcccaaatcc
     5161 tatataagaa cgctcctcta actcacggta atctggctcc ccatgacgta caaagataat
     5221 cttcattcta gtgccctgtc gatccaaatc caccagttcg aacgccatca gctgcatctc
     5281 catctgcaat taagaaagta gcaaaaacag cctggacaat acgttcccca acttcaagaa
     5341 caacctcttg atctgtgata ttcttcatct gcgcaaaaat atgcccttca tttccaggat
     5401 ttccataata atccccatca atgaccccaa ctgagttaat taaaaccaag cccttcttac
     5461 gaggatttga agaacgatca tagaggtaga gaacctcagt cggctgcata taagccttaa
     5521 cccctgtcgg aaccaagaca atctctcctg gcgcaacaac tgtacgcaca gcaaccttta
     5581 agtcgtaacc agccgcatgc gctgtctcac gcttgggcaa taaattttca tctgtaaaac
     5641 tcgaaaccaa ttcaaaacca cgaattttca taattttctc ttttctatta tcatttattc
     5701 tagattattc tatcttattt attcggaaaa agcacgaaaa aaagagcaca caacaattat
     5761 aggcgatacg ataatttaca ctgtttcaca atacgttgaa atttagagct ttaaagcgag
     5821 ggcaaagttg attttttaca tcgttttaca gaggtttacg acacttttgc cccttttttg
     5881 cccctttgtt tttcaaaaaa acttcatcaa atcgcttgac tttcacggtt taccgtgata
     5941 taatataatc aagataagga aaggaggtga ggaagttgaa caaagaagat tggcttaggt
     6001 tactggaaaa ggcgatagat aatatccctg aaacggtaac tgctatagca agtctggtga
     6061 ctgcaataac ggtcgcaagg caaaacaaaa agcgtaaacc gaaatcccgt caaagaaaaa
     6121 ggtgaacgct aagaggttgg ggcgaaagcc cctcacacct ctattttatc aaatgaaaag
     6181 aggaaaagca atggttagtg caatagctat ttttataatt gcggtcaatg tatatattta
     6241 tctaaaaaat aaaaaggaca aataagatga gagaagttat tcaagaattg ttagacagtt
     6301 cgatgtctac atctgctatt tcccaaggtg ctggagttcc atggactact gtttctgacc
     6361 tcagaaaagg aaaaacaagc atggacaaaa tggcacttct cacagcagaa aaactttatg
     6421 aatttgctac aactgataag cagtgatttc ggtcactgtt tttatttttg acaaaacacc
     6481 gtttttgaca ataatcaaaa aataaaaagg agctattatt aacaaaatgg cgtttttggc
     6541 aataataccc tgccattcct cctccctatt cttcaagaaa acgctttttt gaagaatcag
     6601 agcaaataaa aaaccgcaag cctgagcctg cggtgaaaga acaatttaga aagtttcctt
     6661 tctatttatt taactgtaat caagccatct ggctctactg tgaa
//
LOCUS       DAVHTH010000082         6593 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.082, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000082 DAVHTH010000000
VERSION     DAVHTH010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6593)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6593)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6593
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.082"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            267..2558
                     /gene="pcrA"
                     /locus_tag="VVR63_001930"
     CDS             267..2558
                     /gene="pcrA"
                     /locus_tag="VVR63_001930"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000992850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HEU6129902.1"
                     /translation="MNALLNGMNDRQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKLVNPWNILAITFTNKAAREMKERAYSLNPATQDCLIATFHSMCVRILRRDADHI
                     GYNRNFTIVDPGEQRTLMKRILKQLNLDPKKWNERTILGTISNAKNNLIDDVAYAAQA
                     GDMYTQIVAQCYTAYQKELRQSESVDFDDLIMLTLRLFDQNPDVLTYYQQKFQYIHVD
                     EYQDTNHAQYQLVKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPKAKVVL
                     LEENYRSTKTILQAANEVIKNNKNRRPKNLWTQNADGEQIVYYRADDELDEAVFVART
                     IDELSRSQNFLHKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDIIA
                     YLNLIANLSDNISFERIINEPKRGIGLGTVEKIRDFANLQNMSMLDASANIMLSGIKG
                     KAAQSIWDFANMMLDLREQLDHLSITELVESVLEKTGYVDILNAQATLESKARVENIE
                     EFLSVTKNFDDTTDVTEEETGLDKLSRFLNDLALIADTDSGSQETSEVTLMTLHAAKG
                     LEFPVVFLIGMEENVFPLSRATEDSDELEEERRLAYVGITRAEKILYLTNANSRLLFG
                     RTNYNRPTRFINEISSDLLEYQGLARPANTSFKASYSSGSISFGQGMSLAQALQDRKR
                     GAAPKSIQSSGLPFGQFTAGAKPASSEANWSIGDIALHKKWGEGTVLEVSGSGARQEL
                     KINFPEVGLKKLLASVAPIEKKI"
     gene            2601..3281
                     /gene="radC"
                     /locus_tag="VVR63_001931"
     CDS             2601..3281
                     /gene="radC"
                     /locus_tag="VVR63_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000286923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HEU6129903.1"
                     /translation="MYSISFQEDSLLPRERLAKEGVEALSNQELLAILLRTGTRQASV
                     FEIAQKVLNNLSSLTDLKKMTLQELQSLSGIGRVKAIELQAMIELGHRIHKHETLEME
                     SILSSQKLAKKMQQELGDKKQEHLVALYLNTQNQIIHQQTIFIGSVTRSIAEPREILH
                     YAIKHMATSLILVHNHPSGAVAPSQNDDHVTKLVKEACELMGIVLLDHLIVSHSNYFS
                     YREKTDLI"
     gene            complement(3278..3967)
                     /locus_tag="VVR63_001932"
     CDS             complement(3278..3967)
                     /locus_tag="VVR63_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEU6129904.1"
                     /translation="MKKPVIGITGNEKTHPDDDIMMSYAAKGFVEGVKDAGGIPIILP
                     IGDQEMACHYISLIDKLILTGGQNVDPKFYGEPKTIDSDDYHLQRDIFELALIKEAIK
                     QKKPIFSVCRGTQLFNVAMGGTLYQDIEDHWQDSSVEYTTQRLVTEPDTVLQEIYGEI
                     SHINSFHHQSIKDLAPNLKVVAHDPKDGIIEAVMSTDDVAFLGVQWHPELLFENRPKD
                     KKLFDYVVNEL"
     gene            complement(3985..4626)
                     /locus_tag="VVR63_001933"
     CDS             complement(3985..4626)
                     /locus_tag="VVR63_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HEU6129905.1"
                     /translation="MKDKQFAIPKATAKRLSLYYRIFKRFHAEKIERANSKQIAEAIG
                     IDSATVRRDFSYFGELGRRGFGYDVKKLMTFFADLLNDNSITNVMLVGIGNMGHALLH
                     YRFHERNKMKIIMAFDLDDHPEVGTQTPDGIPIYGISQIKDKIKDADVKTAILTVPSV
                     KSQEVANLLVDAGVKGILSFSPVHLHLPKDVVVQYVDLTSELQTLLYFMRKED"
     gene            complement(4709..4924)
                     /locus_tag="VVR63_001934"
     CDS             complement(4709..4924)
                     /locus_tag="VVR63_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HEU6129906.1"
                     /translation="MFELTYKDCYHVERTLKYEDHEALMLTLSGCVTLPDTLYVTSLT
                     FRGKKVYQGLVGDLYRFLSHADFLHQN"
     gene            complement(4932..5279)
                     /locus_tag="VVR63_001935"
     CDS             complement(4932..5279)
                     /locus_tag="VVR63_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HEU6129907.1"
                     /translation="MAFEKIIQLKNCRYDYTLSPSVKKFTLKDNTFFETKVGNYELTR
                     LLEKVPNSGEGFQLKIIINKELTGAKINITDKFGLRLVDIFKSEDHHIHQEKFYFLMD
                     SLVERGVFTKSER"
     gene            complement(5284..6399)
                     /locus_tag="VVR63_001936"
     CDS             complement(5284..6399)
                     /locus_tag="VVR63_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEU6129908.1"
                     /translation="MIYLDNAATTPMSAVAISAMTKVMQETHGNPSSIHGHGRQAGKL
                     LREARQELAQLLRTKPQHIFFTSGGTEGNNTTIIGYCLRHQEQGKHIITTAIEHHAVL
                     ETIDYLVQHFGFEATIIQPENQEITAQQIQKALRDDTILVSTMFANNETGNLLPIAEI
                     GQILKQHPAAYHVDAVQAIGKIPIHSEELGIDFLTASAHKFHGPKGIGFLYASSMDFD
                     SYLHGGDQEQKKRAGTENLPAIVGMVAALKENLEKQEEHFQHVQNLETAFLAELEGIQ
                     YYLNRGKHHLPYVLNIGFPGQKNDLLLLRLDLAGISISTGSACTAGVVQSSHVLKAMY
                     GANSERLKESLRISLSPQNTVEDLQTLAKTLKEIIGG"
     gene            complement(6409..>6593)
                     /locus_tag="VVR63_001937"
     CDS             complement(6409..>6593)
                     /locus_tag="VVR63_001937"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280885.1"
                     /note="catalyzes the formation of 5-phospho-alpha-D-ribose
                     1-phosphate from D-ribose 5-phosphate and ATP; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ribose-phosphate pyrophosphokinase"
                     /protein_id="HEU6129909.1"
                     /translation="AELLDNTNIKEILVTDSVATKEKTPKNVCYITASELIGDAIVRI
                     HERKPVSPLFAYNKKK"
BASE COUNT         1904 a         1283 c         1436 g         1970 t
ORIGIN      
        1 tcgaaatcat cgtaaacgct tcggattacg aatgaatttg agtgctggta ttatcaatca
       61 tgaactagga ttctagtttt gcaggaagtc tattgaggta ttgagctagt ttatgaaaaa
      121 attgggtgaa aagtcgagtg ttttagaaac ccacagtgta gtattctagt ttcaatccac
      181 tatattttgc tactccccgt aaagtttcta ttttccctga tttctgatat aatagaaata
      241 ttgacttcaa gagtaaggaa gagaagatga acgcattatt aaatggaatg aatgaccgtc
      301 aggctgaggc ggtgcaaacg acagaaggtc ccttgctaat catggcaggg gctggttctg
      361 gaaagactcg tgttttaacc caccgtatcg cttatttgat tgatgaaaag ctggtcaatc
      421 cttggaatat cttggccatt acctttacca acaaggctgc gcgtgagatg aaagagcgtg
      481 cttatagcct caatccagct actcaggact gtctgattgc gaccttccac tccatgtgtg
      541 tgcgtatttt gcgtcgcgat gcggaccata ttggctacaa tcgtaatttt acaattgtgg
      601 atcctggtga acagcgaacg ctcatgaaac gtattctcaa acagttgaac ttggatccta
      661 aaaaatggaa tgaacgaact attttgggga ccatttccaa tgctaagaat aatttgattg
      721 atgatgttgc ttatgctgcc caagctggcg atatgtatac gcaaattgtg gcccagtgtt
      781 atacagccta tcaaaaagaa cttcgtcagt ctgaatccgt tgactttgat gatttgatta
      841 tgctgacctt gcgtctcttt gatcaaaatc ctgatgtttt gacctactac cagcaaaaat
      901 tccaatacat ccacgttgat gagtaccaag ataccaacca cgctcagtac caattggtca
      961 aactcttggc ttcccgtttt aaaaatatct gtgtggttgg ggatgcggac cagtctatct
     1021 acggttggcg tggtgctgat atgcagaata tcttggactt tgaaaaggat taccccaaag
     1081 ccaaggttgt tttgttggag gaaaattacc gctcaaccaa aaccattctc caagcggcca
     1141 acgaggttat taaaaataat aaaaatcgcc gtcctaaaaa tctctggact caaaacgctg
     1201 atggggagca aatcgtttac tatcgtgccg atgatgagct ggatgaggct gtatttgtag
     1261 ccagaaccat cgatgaactt agtcgcagtc aaaacttcct tcataaggat tttgcagttc
     1321 tctatcggac taatgcccag tcccgtacaa ttgaggaagc cctgctcaag tctaacattc
     1381 cttataccat ggttggcgga accaaattct acagccgtaa ggaaattcgc gatattattg
     1441 cttatctcaa ccttattgct aatttgagtg acaatattag ttttgagcgt attatcaacg
     1501 agcctaaacg tggaattggt ctaggtacag ttgagaaaat ccgtgatttt gcaaatttgc
     1561 aaaatatgtc tatgctggat gcttctgcta atattatgtt gtctggtatc aagggtaagg
     1621 cagcccaatc tatctgggat tttgccaata tgatgcttga tttgcgggag cagctagacc
     1681 acttaagcat tacagagttg gttgagtccg tcctagaaaa aacaggttat gtcgatattc
     1741 ttaacgccca agcgactcta gaaagcaagg cacgggttga aaatatcgaa gagtttcttt
     1801 ctgttacgaa gaactttgat gacaccacgg atgtgacaga agaggaaact ggtctggaca
     1861 aactgagtcg tttcttaaat gacttggctt tgattgccga cacagattca ggtagtcagg
     1921 agacatcaga agtgaccttg atgaccctgc atgctgccaa aggtctcgaa tttccagttg
     1981 tctttttgat tgggatggaa gaaaatgtct ttccacttag tcgtgcgact gaagattcag
     2041 atgaattaga agaagagcgc cgtctagcct atgtaggtat cacgcgtgca gagaaaattc
     2101 tctatctgac caatgccaac tcacgcttgc tttttggtcg taccaattat aaccgtccga
     2161 ctcgttttat taacgaaatc agttcagact tgcttgagta tcaaggtctg gctcgtcctg
     2221 caaatacaag ctttaaggca tcatatagca gtggtagtat ttcctttggt caaggtatga
     2281 gtttggctca ggctcttcaa gaccgtaaac gcggtgctgc cccaaaatca atccagtcaa
     2341 gcggtcttcc atttggtcaa tttacagctg gcgcaaaacc agcatctagc gaggcaaatt
     2401 ggtccattgg tgatattgct ctccacaaga aatggggaga gggaaccgtt ctggaagttt
     2461 caggtagcgg tgctaggcag gaattgaaaa tcaatttccc agaagtaggt ttgaaaaaac
     2521 ttttagccag tgtggctcca attgagaaaa aaatctaatt ttccatcctt ctcacgaata
     2581 ataaagtgag gaggattttt atgtacagta tttcattcca agaagattca ctattaccaa
     2641 gagaaaggct ggccaaggaa ggagttgaag cgcttagtaa ccaagagttg ctagctattt
     2701 tactcaggac aggaacacgt caagctagcg tttttgaaat tgcccaaaaa gtcttgaaca
     2761 atctttcaag cctaacggat ttgaaaaaaa tgaccctgca ggaattgcag agtttgtctg
     2821 gtattgggcg tgttaaggcc atagaattac aagctatgat tgaactgggg catcgtattc
     2881 acaaacacga gactcttgaa atggaaagta ttctcagcag tcaaaagttg gccaagaaga
     2941 tgcagcagga attaggggat aaaaaacaag agcacctggt ggcactctat ctcaatactc
     3001 aaaatcaaat catccatcag cagaccattt ttatcgggtc tgtaactcgt agtatcgctg
     3061 aaccgcgaga gattcttcac tatgcaatca agcatatggc gacttctctt atcttggtcc
     3121 acaatcatcc ttcaggagcg gtagcgccta gccaaaatga tgatcatgtc actaaacttg
     3181 ttaaagaagc ctgcgaattg atggggattg ttctcttgga ccatttgatt gtctctcatt
     3241 ctaattactt tagttatcgt gaaaagacag atttaatcta aagttcatta acgacatagt
     3301 caaagagttt tttatctttg ggacgatttt caaaaagaag ttctggatgc cattggacac
     3361 cgagaaaggc gacatcatcc gtactcatga cagcctcaat gataccatct ttaggatcat
     3421 gagccacaac ttttaaattt ggtgctaagt ccttgatgct ctggtggtgg aaggagttga
     3481 tatgagagat ttctccatag atttcttgga gaacggtatc tggttctgtt accaagcgtt
     3541 gagttgtgta ctcaacagaa gaatcctgcc aatggtcttc gatatcttgg tacaaagttc
     3601 cacccatggc aacgttaaag agttgggtac cacggcagac agagaaaatg ggctttttct
     3661 gtttaatagc ttccttgatg agggccagtt cgaagatatc tctttgaagg tgatagtcat
     3721 cactatcaat ggttttgggt tcgccataaa attttggatc gacattttgc ccacctgtca
     3781 agatgagctt gtcaatcaaa ctgatatagt ggcaggccat ttcttgatca ccaatcggta
     3841 ggatgatggg aatccctcca gcatctttaa cgccttcaac aaagcctttt gctgcgtagc
     3901 tcatcatgat gtcatcatct ggatgagttt tttcgtttcc tgtaatccca ataactggtt
     3961 ttttcataaa atgattttcg ctttctaatc ctcttttcgc atgaagtaga ggagggtttg
     4021 gagttcactt gtcaaatcga catactgaac gaccacgtct tttggtaaat gcagatggac
     4081 tggtgaaaaa ctgagaattc ctttcacacc agcatcaacc aagagattag caacctcttg
     4141 tgacttgacg ctgggaacag ttaggatagc agtcttcaca tcagcatcct tgattttatc
     4201 cttgatctga gaaatcccgt aaatgggaat cccgtcagga gtttgggtac cgacttcagg
     4261 atggtcgtct aggtcaaagg ccatgataat cttcatcttg ttacgttcgt ggaagcggta
     4321 gtggagaagg gcatggccca tatttccaat accaaccagc atgacattgg taatagagtt
     4381 gtcattgagc aaatcggcaa aaaatgtcat tagttttttg acatcatagc caaaaccacg
     4441 ccgaccaagt tcaccaaaat aggaaaaatc acgacgtacg gtcgctgaat caataccgat
     4501 agcctctgca atttgcttag agttggcacg ttcaatcttt tctgcatgaa atctcttaaa
     4561 aattcgatag tagagagaga gtctttttgc tgtagctttt ggaatagcaa actgtttatc
     4621 tttcacaaaa tcacaacctt tctattcttc tattttatag aaacattgtg aaaaaatcaa
     4681 caaaaataag aaaaaactaa gaaaaatctt agttttgatg taaaaaatct gcatgagata
     4741 gaaaacggta gaggtctccg accagcccct gataaacttt tttgccccta aaagtcagag
     4801 aagtcacata aagtgtatct ggtaaggtta cacatcctga caaagtcaac atgagagcct
     4861 catgatcctc atacttgaga gtacgctcta catgatagca gtccttatag gtcagttcaa
     4921 acattttggc tctatctttc cgattttgta aagacaccac gttctaccaa gctatccatg
     4981 aggaagtaga atttttcctg atgaatatgg tggtcttctg atttgaaaat atcaactaga
     5041 cgaaggccaa acttgtcagt gatattgatt ttagcccctg taagttcctt gttaatgatg
     5101 attttgagtt ggaagccttc accgctgttt ggcacttttt ccaaaaggcg agtcagttca
     5161 tagttaccaa ccttagtttc aaaaaaggtg ttatctttga gggtgaattt tttaacagaa
     5221 gggctaagag tgtaatcgta acgacaattt tttaactgaa tgattttttc aaatgccata
     5281 tggctaacct ccgataattt cttttaaggt ttttgcgagg gtttgtaggt cttcaacggt
     5341 attttgtggc gacaaactga tgcgaaggga ttccttcaag cgttctgaat ttgcgccata
     5401 catggcttta agaacatggc tggattggac aacgcctgca gtacaggctg agccagtaga
     5461 gattgaaatt ccagctaaat ctagccgaag gagtaagagg tcatttttct gaccaggaaa
     5521 tccaatattg agaacataag ggagatgatg ttttcctcta ttcaagtaat actgaatgcc
     5581 ctccagctct gccagaaagg cagtttctag attttgtaca tgttgaaaat gttcttcttg
     5641 tttttctagg ttttctttta gagctgcaac catgcctacg atggcaggca gattttcagt
     5701 tcctgcacgt tttttctgtt cctggtctcc gccatgtaga taggaatcaa agtccatgct
     5761 agatgcgtag agaaaaccga ttcccttagg accatggaat ttgtgggcag aagcagtgag
     5821 aaaatcaatg cccaattctt ctgaatgaat tgggatttta ccaatagcct gaactgcatc
     5881 aacatgatag gcagcagggt gttgcttgag tatttggcca atttcagcga tgggcagtag
     5941 gtttcctgtc tcattattgg caaacatggt agaaaccaaa atcgtatcgt cacgtaaagc
     6001 cttttgaatt tgctgggctg tgatttcttg attttctggc tggataatgg ttgcttcaaa
     6061 cccaaagtgt tgaaccaagt aatcaattgt ttcaaggaca gcatggtgct cgatggcagt
     6121 tgtgatgata tgttttcctt gttcttggtg acgaagacag tagccaatga tggtagtatt
     6181 attgccttca gtcccaccag aagtgaaaaa gatatgttga ggttttgtcc ttagtaactg
     6241 ggctagttcc tgacgggctt ctcgcaagag tttgccagct tgacgaccat gaccatgaat
     6301 actagaagga tttccgtggg tttcttgcat aaccttggtc atagctgaaa tagcaactgc
     6361 tgacatagga gtcgttgcag cattgtccaa ataaatcaaa gaatcacctt atttcttttt
     6421 attgtaggca aagagtgggc tgactggttt tctttcgtga atacggacga tagcatcacc
     6481 aattaactca ctagcagtga tgtagcatac atttttagga gttttttctt ttgttgctac
     6541 tgaatcagtc acaagaattt ctttaatatt agtattgtca agaagctcag cag
//
LOCUS       DAVHTH010000083         5922 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.083, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000083 DAVHTH010000000
VERSION     DAVHTH010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5922)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5922)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5922
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.083"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            <1..715
                     /locus_tag="VVR63_001938"
     CDS             <1..715
                     /locus_tag="VVR63_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="aminoacetone oxidase family FAD-binding enzyme"
                     /protein_id="HEU6129910.1"
                     /translation="CEKLIVTTGGKSYPSTGSTGFGHEIARHFKHTITDLEAAESPLL
                     TDFPHKALQGISLDDVTLSYGKHVITHDLLFTHFGLSGPAALRMSSLVKGGEVLSLDV
                     LPQLSEKDLVTFLEENREKSLKNALKTLLPERLAEFFVQGYPEKVKQLTEKEREQLVQ
                     SIKELKIPVTGKMSLAKSFVTKGGVSLKEINPKTLESKLVPGLHFAGEVMDINAHTGG
                     FNITSALCTGWVAGSLHYD"
     gene            735..1190
                     /locus_tag="VVR63_001939"
     CDS             735..1190
                     /locus_tag="VVR63_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEU6129911.1"
                     /translation="MNRREAVEFVNMCMIKNGDKILVQDRVSPDWPGITFPGGHVERG
                     ESFVDAVIREVKEETGLIISKPQLCGIKNWYDDKDYRYVVLFYKTEHFTGELQSSDEG
                     KVWWEDFENLSHLKLATDDMSDMLRVFLEEDLSEFFYYKNGDDWLYDLK"
     gene            complement(1219..1964)
                     /locus_tag="VVR63_001940"
                     /pseudo
     CDS             complement(1219..1964)
                     /locus_tag="VVR63_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000274781.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
     gene            2265..3532
                     /locus_tag="VVR63_001941"
                     /pseudo
     CDS             2265..3532
                     /locus_tag="VVR63_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001851261.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
     gene            complement(3553..4497)
                     /gene="manA"
                     /locus_tag="VVR63_001942"
     CDS             complement(3553..4497)
                     /gene="manA"
                     /locus_tag="VVR63_001942"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HEU6129912.1"
                     /translation="MSEPLFLQSVMQEKIWGGAKLRDEFGYDIPSEKIGEYWAISAHP
                     NGVSKVANGRYEGTDLATLYAEHRELFGNRPEPVFPLLTKILDANDWLSVQVHPDDAY
                     GLEHEGELGKTECWYIIAADEGSEIIYGHNAKSKEELRQQIEDKNWDDLLTKVPVKAG
                     DFFYVPSGTMHAIGAGILILETQQSSDTTYRVYDFDRKDDKGNLRELHLEKSIDVLNI
                     GEPANSRPVTVKADDLRSTLLVSNDFFAVYKWEITGKVDFEKTADYSLLSVLAGQGQL
                     TVDGKNYPIQKGRHFILPSDVEAWTLEGQGLELIVSHP"
     gene            complement(4629..4910)
                     /locus_tag="VVR63_001943"
     CDS             complement(4629..4910)
                     /locus_tag="VVR63_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HEU6129913.1"
                     /translation="MDTPDENGYVADDYRITYLEAHIKAMRDAIYKDGVDLLGYTTWG
                     CIDSVSAGTGEMNKRYGFIYVDRDNVGNGTLKCSKKKSFYWYMSFIAMV"
     gene            5230..5922
                     /locus_tag="VVR63_001944"
                     /pseudo
     CDS             5230..5922
                     /locus_tag="VVR63_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT         1620 a         1252 c         1208 g         1842 t
ORIGIN      
        1 ttgtgagaaa ctcattgtca caacaggtgg taagtcttat ccttcgactg gttcgactgg
       61 ttttggtcac gagattgctc gccattttaa gcataccatc accgatcttg aggctgctga
      121 aagtccttta ttaacagatt ttccacataa agccttacaa gggatttctc tggacgatgt
      181 gaccctaagt tatggtaagc atgtcatcac tcatgattta ctctttaccc actttggttt
      241 gtcaggtcct gctgccctac gcatgtctag cttggtcaaa ggtggggagg ttctctcact
      301 cgatgttttg cctcaacttt ctgagaagga cttggttaca tttctagaag aaaatcggga
      361 aaaatccttg aaaaacgctt taaaaacctt gttaccagaa cgcttggccg aattttttgt
      421 acaaggatat cctgaaaaag tcaaacagct gactgaaaag gaacgagaac aacttgtcca
      481 gtccattaaa gaacttaaaa ttcctgtaac tggaaaaatg tcccttgcaa agtcctttgt
      541 taccaagggt ggagtcagtc tcaaggaaat caatcctaaa acccttgaaa gtaagctggt
      601 acctggcctc cactttgcag gcgaagttat ggatatcaat gcccacacgg gtggctttaa
      661 catcacttct gctctctgta ccggctgggt ggcgggaagt ctgcattatg attaaagatt
      721 aaaggttgtg aagaatgaac agaagagagg cagtcgaatt tgttaacatg tgtatgatta
      781 aaaacggaga taagatcctg gtccaagacc gagttagtcc cgactggcct ggcattactt
      841 ttcctggtgg tcatgttgaa cgtggcgaat cctttgtcga tgctgtcatt cgtgaagtga
      901 aagaagaaac tggtctgatc atttccaaac cccaactctg tggtattaaa aactggtatg
      961 acgacaagga ttatcgttat gtcgtccttt tttacaagac agaacacttt actggtgaac
     1021 tccagtcttc agacgaaggg aaagtttggt gggaggactt tgaaaatctt tctcatctaa
     1081 aacttgcaac cgatgatatg tctgatatgc ttcgtgtgtt tctagaagaa gatctcagtg
     1141 aattctttta ctacaaaaac ggtgacgact ggctttatga tttgaagtaa aaaataggct
     1201 aggaaattcc tagcctattt attctgcatt tgtctgaacg taagccgcaa tggcatctga
     1261 cgtgtactgg gctgttccag aaccaaactt gtcaatgttt tccttaaact ctgggttgta
     1321 gacgtaacct ttaccgatat gaccgaatat ctcaatagag cagtcaaatc cataagtgcg
     1381 aatagcttgc aagagcttgg ctgcttgctc ttggttttcg gttgctgttg caggtaaacc
     1441 aacttgaaga ttttgtgcca aagtttgaaa gacttggtta aaggcggccg tagcctcgtc
     1501 ttcgtgacct ttttggcgtt cgagcgcttg tcccatgact tcttgaccat atttctctac
     1561 cgcttcttgg tggtattttt gattgtcttg atagctaaat cccgtgaatt tttcctcaat
     1621 ggtcattttt ctttctcctt tttgttcttg aatagttttt tgcaaggtgg aaatcaaggt
     1681 atccagatgt tgcctttcgc gagttagata gtccaactgc ctagttaaat ggggcaataa
     1741 atctgtcctt tcttccttta acagctctgc tattttctct aaagaaaagc ctagatattt
     1801 gtagtaaaga atgacctgaa ggcgttccaa atcctcttga ctataggttc gatagccgtt
     1861 ttccgacttt aaggggacca agagtcctat cttgtcatag tgatgcaggg cagggtcttg
     1921 acagagacac ctgaaagctg cgcagcttct tttatatggt acatgatttc ctccttacaa
     1981 tgatagtata acccctcccc ttaggtcaga gtcaagcgtt tttgagaaag gtgtgaaaac
     2041 ttgaaaatgg ttttcttgac agaccttaga aaacataata ggatagtcaa gtctatcaat
     2101 caaacagaag gctatttgac aactcaagta gctttttctt attttgaaaa aggagatcag
     2161 agtttaacta tgtcagaaaa atcacaatgg gggtcgaaac ttggttttat tctagcatct
     2221 gctggctggc catcgggctt ggtgccgttt ggaagtttcc ctacatgact gctgctaatg
     2281 gcggtggagg ctttttacta atctttctca tttccactat tttaatcgat ttccctctcc
     2341 tgctggctga gtttgccctt ggccgtagtg ctggcgtttc cgctatcaaa acctttggaa
     2401 aactgggcaa gaataacaag tacaacttta tcggttggat tggcgccttt gccctcttta
     2461 tcctcttatc tttttacagt gttatcggag gatggattct agtctatcta ggtattgagt
     2521 ttgggaaatt gttccaactt ggtggaacgg gtgattatgc tcagttattt acttcaatca
     2581 tttcaaatcc agccattgcc ctaggagctc aagcagcctt tatcttatta aatatcttta
     2641 ttgtatcacg tggggttcaa aaagggattg aaagagcttc gaaagtcatg atgcccctgc
     2701 tctttatcat ctttgtcgtc atcatcgaac gctctcccag tttgccaaat gccatggaag
     2761 gggttcttta cttcctcaaa ccagactttt caaaactgac tagcgctggt cccctctatg
     2821 ctctgggaca atctttcttt gccctctcac taggggttac agtcatgctg acctatgctt
     2881 cttacttgga caagaaaacc aatctagtcc agtcaggaat ctccatcgta gccatgaata
     2941 tctcgatatc catcatggca ggtctagcca ttttccaagc tcggtccccc ttcagactgg
     3001 atattgaagg gggaccgagc ttgctcttta tcgtcttgcc tcaactcttt gacaagatgc
     3061 cttttggaac cattttctac gtccttttcc tctttgcgac tgtcacttct tctgtcgtga
     3121 tgctggagat caatgtgggc aatatcacca accaggataa cagcaaacgt gccaaatgga
     3181 gtgttatttt aggaattttg acctttgtct ttggcattcc ttcagcccta tcttacggtg
     3241 tcatggcgga tgttcacatt tttggtaaga tcttctttga cgctatggac ttcttggctt
     3301 ccaatctcct catgccattt ggagctctct acctttcact ttttacaggc tatatcttta
     3361 aaaaggctct tgcaatggag gaactccatc tcgatgaaag agcatggaaa caaggactgt
     3421 tccaagtctg gctcttcctt cttcgtttct tcgtttcttc gtttcgtcat tccaatcatc
     3481 atcattgtgg tcttcattgc ccaatttatg taatcaaaaa ggacttgagt agtgaactca
     3541 ggccctttct ttttatggat ggctaacaat caattccaaa ccttgccctt ccagagtcca
     3601 agcttcaaca tcacttggta ggataaagtg tctccctttt tgaattggat aatttttccc
     3661 gtcaacagtt agctgacctt gaccagctaa gacactcaat aagctgtagt cagctgtctt
     3721 ttcaaagtca acttttccag taatttccca cttgtaaact gcgaagaaat cattagatac
     3781 aaggagagtg gaacgcaaat catctgcttt aacagttaca ggacggctat ttgctggctc
     3841 accaatgttc aagacatcga tggatttttc aagatgaagt tcacgcaagt tgcctttgtc
     3901 atccttgcgg tcaaagtcat agacgcgata ggtggtatcg ctagactgct gggtttcaag
     3961 gattaagata cccgccccga tagcgtgcat agtcccgctt ggtacataga agaaatctcc
     4021 agccttaaca gggactttgg tcaacaagtc atcccagttc ttgtcctcga tttgctggcg
     4081 gagttcttct tttgacttgg cattgtgacc gtagataatc tctgaacctt catccgctgc
     4141 gataatgtac cagcattctg tttttccgag ttcgccttca tgctcgagtc cataagcatc
     4201 gtctgggtga acttggacac tgagccagtc gttggcatcg aggatcttgg tcaaaagtgg
     4261 aaatacaggt tctggacgat tgccaaataa ttcacggtgt tccgcataca aagtagcaag
     4321 atctgttccc tcgtaacgac cattggcaac tttagagact ccatttggat gggctgagat
     4381 ggcccaatat tctccgattt tttcacttgg gatgtcgtag ccaaactcat cacgtagctt
     4441 ggctccaccc cagatttttt cttgcataac tgattgtaaa aataatggtt ctgacatgtc
     4501 gatctcctgt ctgatttttc tcccctcatt atagcaaaaa aagagttcga attgaactct
     4561 tttttacatc ttataaagca gggagaagat tttataaaaa tagtaaacaa atgtgctcta
     4621 ctcgatgctt acaccattgc tataaatgac atgtaccaat agaaggactt cttcttgcta
     4681 catttgagag tcccatttcc tacattatct cgatctacat agataaagcc atagcgctta
     4741 ttcatttccc ctgtgccagc tgaaaccgaa tcgatacagc cccatgtcgt ataaccaagc
     4801 aagtcaaccc cgtctttgta aatggcatct cgcatggcct tgatgtgggc ctctaagtaa
     4861 gtaatccgat agtcatctgc tacataacca ttctcatccg gtgtatccat agcaccgagt
     4921 ccattttcta cgataatact atactaaaat caaaaagcat tatataatag tgatatgaaa
     4981 tcaactaaag aagaaatcca aaccatcaaa acacttttta aagactctcg tacagctaaa
     5041 tatcataaac gccttcaaat cgttctatag taaaacgaaa caagaacagg gcaaatcgat
     5101 caggacagtc aaatcgattt ctaacaatgt tttagaagta gaggtgtact attctagttt
     5161 caatttatta tatttcgtct gatgggcaaa tcttataaag agattataga acttttatag
     5221 tagtttgaaa taagatgtga acaactctat caggaaagtc aaactaattt atagaaatat
     5281 tttagcagct aaggtgtact gttatagatt caatacacta tagactgtaa tcaaacaacg
     5341 atttggcgaa atgtaaaaaa atatgaggag ttcgaactcg actctctcct tcaagaaaca
     5401 cgtggtggcc gtaaccatgc atatatgacg attgaggaaa agaaagtctt tcttgcccgc
     5461 catttgaagg ctacagaggc aggagaattt gttacaattg atgccttatt tcaggcttat
     5521 aaaaaggagt taggtcgttc ctacacacgt gatgccttct atcaactgtt gaagcgccat
     5581 ggttggcgaa atattatgcc acgtccagaa catcctagga aagcagacgc tcaaaccatt
     5641 gtcgcgtcta aaaataaaat ctcaattcaa gaagaaaaga aagcgcttta aaagcagtag
     5701 acgttttcgt aaggttcgct tgatgtacca agatgaggct ggtttcggta gaatcagtaa
     5761 actgggatct tgttgggctc caataggagt aggtccacat gtccatagtc actatatacg
     5821 agaatttcac tattgttatg gagctgttga tgcccataca ggcgaatcat ttttcttaat
     5881 agctggtgga tgtaatactg agtggatgaa cgccttttta ga
//
LOCUS       DAVHTH010000084         5575 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.084, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000084 DAVHTH010000000
VERSION     DAVHTH010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5575)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5575)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5575
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.084"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            complement(107..748)
                     /locus_tag="VVR63_001945"
     CDS             complement(107..748)
                     /locus_tag="VVR63_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6129914.1"
                     /translation="MIELKNITKTIGGKVILDNLSLRIDQGDLVAIVGKSGSGKSTLL
                     NLLGLIDGDYSGRYEIFGQTNLAVNSAKSQTIIREHISYLFQNFALIDDETVEYNLML
                     ALKYVKLPKKDKLKKVEEILERVGLSATLHQRVSELSGGEQQRIAVARAILKPSQLIL
                     ADEPTGSLDPENRDLVLKFLLEMNREGKTVIIVTHDAYVAQQCHRVIELGEGK"
     gene            complement(745..2853)
                     /locus_tag="VVR63_001946"
     CDS             complement(745..2853)
                     /locus_tag="VVR63_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000723955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEU6129915.1"
                     /translation="MKKISNFCMLLLLLCTTFFVFNVNYTREVVRIQEMGKTVDSLDL
                     YLKDINEPAASVLRFFEDVSKEYKVSIIKTDSGDEVVKSGVFDKDTFPYQEFGISSLD
                     FTTDGEGVYSNKEISNKLGTIPTFLKAKPIQLMTFQTYIKDTSRSLNGRYTITSTQEM
                     DKDRIVQKWSDFFKIDQATLLEPTYKSAVEVINRDLLLSAIVFVLAILLLVLVTVYQP
                     MMEMKRVGVQKLLGFQDRAVLADVVKGNLYLLLGGALVINLGVFFLLDYKPKDLFPML
                     WLSHFLLLQLYLFISWLTYLLIQKMTISSLLKGFSSFKFGLIFNYVMKIGTTILLTAL
                     LIGVGRSLEQENKELAYQQQWVSQGNYLTLETFKLNDNLWQEELAGSGKSTDYFYRFY
                     QDLVEKTQAGYVQSSSLPVKNFVQSEQIQQYQLTDTVDVYYANRNFLKSKGFKLPDTG
                     IKKVILMPASTKGEEDKNQLLGKLIAFHSMKYEEQQKRTIEEMDVEIAYYEGDWSFFP
                     YSDKRKENLSNPIISLVNDSDMMWDEKASLSTTGLNNPIKIENTVQHQKEITELVEKL
                     SDGNYLKFSSIQAIQQEKVDSYRDAVRNFNLLFALFGLLSMMISYFLLVTTFLLKRRD
                     IITKKFMGWKLVDRYRPLLVLLLLGYSFPLLVLIFFAHAFLPLLLFAGFTCLDILFVL
                     GLASRMEKRSLVELLKGGIL"
     gene            complement(2905..3192)
                     /locus_tag="VVR63_001947"
     CDS             complement(2905..3192)
                     /locus_tag="VVR63_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001230165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEU6129916.1"
                     /translation="MRKLVKIGVASLMVCGILATTNALAVWVEGGQWNYGVGWTGTFG
                     YSDYLHSTRYHTATVRHGGRTSKDYAKPEAWARASLTKIPPTGMEYFYGFE"
     gene            3623..3943
                     /locus_tag="VVR63_001948"
     CDS             3623..3943
                     /locus_tag="VVR63_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEU6129917.1"
                     /translation="MQRLEVYKNYQHLYDLRMTILLNLSTLYLYNQDKNMCKQICYTL
                     LEDAKNKKSYDRLAICYVRIGICRDDAKLIQKGFSLLELTEETSMLSHLKKEVETHYQ
                     PKKL"
     gene            complement(4233..4703)
                     /locus_tag="VVR63_001949"
     CDS             complement(4233..4703)
                     /locus_tag="VVR63_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
                     /protein_id="HEU6129918.1"
                     /translation="MRMPLKHPLKNRKKEKNMSKEKVILAYSGGLDTSVAITWLKKDY
                     DVVSVCMDVGEGKDLDFIHDKALKVGAVESYVIDVKDEFATDYVLVAHQSHAYYEQKY
                     PLVSALSRPLISKKLVEIAHQIGATTIAHGCTGKGNDQVEYQIAVAKKANEAKK"
     gene            complement(4669..5475)
                     /locus_tag="VVR63_001950"
     CDS             complement(4669..5475)
                     /locus_tag="VVR63_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001038484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEU6129919.1"
                     /translation="MNKMKKVLMTMFGLVMLPQLFACSNNQSAGIEAIKSKGKLVVAL
                     NPDFAPFEYQKVVDGKNQIVGSDIELAKAIATELGVELELSPMSFDNVLASVQSGKAD
                     LAISGVSKTDERSKVFDFSTPYYTAKNKLIVKKSDLATYQSVNDLAQKKVGAQKGSIQ
                     ETMAKDLLQNSSLVSLPKNGNLITDLKSGQVDAVIFEEPVAKGFVENNPDLAIADLNF
                     EKEQDDSYAVAMKKDSKELKEAVDKTIQKLKESGELDKLIEDAFKASIEK"
BASE COUNT         1739 a         1227 c          894 g         1715 t
ORIGIN      
        1 aaaaaaaacc tagaaatact acataaaatg tcattcctag gcgtatttat gctatttttc
       61 tctggaaaac atgagtattc agccagtcaa aaggagctga atgaactcat tttccctcgc
      121 ccaattcaat gacacgatga cattgttggg ctacataagc atcgtgggtc acaataatga
      181 ctgttttccc ttctcgattc atctctaaga gaaacttcaa gaccaaatct ctattttcag
      241 gatccagcga acctgtaggt tcatcggcta aaatcagctg gctgggtttt aagatggctc
      301 tagcaactgc aattcgttgt tgttcgcccc cagacaactc ggagaccctt tgatgcaaag
      361 tagctgacaa acctactctc tctaaaatct cttccacctt tttgagcttg tctttcttag
      421 gcaatttcac atatttcagc gccagcatga gattgtactc gaccgtttca tcatcaatca
      481 gggcaaaatt ttgaaacaga taagagatat gttcacggat tattgtttgc gacttagcag
      541 aattaaccgc tagatttgtc tgaccaaaaa tctcataccg tccgctataa tcaccatcta
      601 tcaaacccaa taaatttaac aaggtcgact tcccactacc actcttacca acaatagcta
      661 ccaaatcccc ctgatcaatc ctgagagata agttatccaa aatcactttt cccccaatgg
      721 ttttggtaat atttttcaac tcaatcataa gatgccccct ttcaataact ctactagact
      781 tcttttctcc atcctagaag ctaagcctag cacaaatagt atatccagac atgtaaaacc
      841 tgcaaacagt agaagtggta agaacgcatg ggcaaagaaa atcaagacta gaagagggaa
      901 actatagccc agcaagagca gaacgaggag aggacggtag cgatcgacca gtttccaccc
      961 cataaacttc ttggtaatga tatccctgcg cttcaataag aaagttgtta ctagtaagaa
     1021 gtaggaaatc atcatgctaa ggagaccaaa caaagcaaag agtaggttaa aattccgaac
     1081 agcatctcga taagaatcca ctttctcttg ttgaatggct tgaatagatg aaaattttaa
     1141 ataatttcca tctgacaatt tctcaactag ctctgtaatc tctttttgat gttgaaccgt
     1201 attttcaatt ttaatcggat tatttaagcc agttgttgac agggaggctt tctcatccca
     1261 catcatatca gaatcattga ccaagctaat aattggattg gagagatttt cctttcgctt
     1321 atcactatat gggaaaaatg accaatctcc ttcataatag gcaatctcga catccatctc
     1381 ctctatcgtt cgtttttgct gctcttcata cttcatcgaa tgaaaggcaa ttaacttccc
     1441 caagagctga tttttatctt cttcaccttt cgtacttgct ggcatcaaaa taactttttt
     1501 aataccggta tctggtagct tgaatccctt gctctttaga aaattgcgat tggcatagta
     1561 aacatccacc gtatctgtta actgatattg ctgaatctgt tctgattgga caaaattttt
     1621 tacaggaaga ctgctactct gcacatagcc cgcctgcgtt ttttctacca aatcctgata
     1681 aaatcgatag aaataatctg tagatttccc tgaccctgct agctcttctt gccacagatt
     1741 atcattgagt ttgaaggttt ctaaggtcag gtaattacct tgacttaccc actgttgctg
     1801 ataagcaagt tctttgtttt cttgttctaa acttctgccc accccaatca gtaaggccgt
     1861 cagtaaaata gttgtcccta ttttcatcac ataattgaag ataagaccaa atttgaaaga
     1921 tgaaaaacct ttcagcagag agctgattgt cattttttgg attaagaggt aagtcaacca
     1981 actgataaag agataaagct gcaacagcaa aaaatgagac aaccacagca taggaaacaa
     2041 atcttttggc ttataatcaa gcaagaaaaa cacgcctaga ttgatcacaa gagccccacc
     2101 taggaggagg taaaggttgc cttttacaac atcagctaaa acagccctat cttgaaaacc
     2161 aagtaatttt tgtaccccaa ctcttttcat ctccatcatc ggttgataca ctgtcactaa
     2221 cacaagaagc aaaatagcca agacaaaaac aatggcagat aaaagcaaat ctcgatttat
     2281 gacttccact gcacttttgt aggtcggctc tagcaaggta gcctggtcta tcttgaaaaa
     2341 atcgctccat ttctgtacaa tcctatcctt gtccatctct tgtgtagaag ttatcgtata
     2401 gcgaccattt aaactacgag atgtatcctt gatataggtt tgaaaagtca taagctgaat
     2461 aggtttggct tttagaaagg tcggaatcgt accaagttta ttggaaattt ctttattact
     2521 atagactcct tcaccatctg tggtaaaatc aagagaagaa atcccaaact cttggtaggg
     2581 gaaggtatct ttatcaaaaa caccagactt gaccacctca tcaccactgt ctgttttgat
     2641 gatggagact ttatactcct ttgatacatc ctcaaaaaat cgaagaacag acgctgcagg
     2701 ttcgttaata tctttcaaat acaaatccaa agaatctaca gtctttccca tttcttgaat
     2761 ccgaaccact tctcgtgtat agtttacatt aaaaacaaaa aaagtggtac acagaagcag
     2821 gagtaacata cagaaattac tgattttttt cataaaagtg cctccactac agttttccct
     2881 ctccaaatag gagagggaag aattttactc aaatccatag aaatattcca ttcctgttgg
     2941 cggaatcttg gtgagggaag ctctagccca tgcctcaggt tttgcataat ccttagaggt
     3001 tctaccccca tgtctaacag ttgctgtatg atatcgagta gaatgtaagt aatcagaata
     3061 tccaaaagtt cctgtccaac ctactccata gttccattga ccaccctcaa cccatactgc
     3121 taaagcattt gtagtagcaa gtataccaca taccattaaa gatgcaacac caattttaac
     3181 taattttctc atgatttatt tctcctatta tcgagagctg ttccgtaaaa acagctatag
     3241 taatttatca acaagtatcg tagtccattg gactcacctt ccttctatct catttcattt
     3301 tttaacaacg aacttactct taaccgggag aatggtgcgc ttctgtatca ggtccttgaa
     3361 caaccagagt agtattaagc aaactctaac tattactcaa gaatcagtcc aataaacaat
     3421 atggatagcg ctttcaaatt tttaaactcc tatcccgtcc ttttatctat ataataagca
     3481 taagcgaaaa tataataact gtcaagtaac tgaagtgaat tttataaaaa aattacaagc
     3541 caaatttgta aagtttacac taagccgcta gggcaatcgt ctatcagaat gtccgtttat
     3601 ttgtcaataa tccgagaaaa tcttgcaacg cttagaagtc tataaaaact atcaacattt
     3661 atatgacttg cgaatgacaa ttctattaaa cctttccaca ctctatctat acaatcaaga
     3721 taaaaacatg tgtaagcaaa tctgctacac tttactggag gacgccaaga ataagaaaag
     3781 ctacgatagg ctggctatct gctatgtccg tattgggatt tgtagggatg atgcgaaact
     3841 tatccaaaaa gggttctcac tcctagagct gaccgaggaa acttctatgc tgtctcatct
     3901 caaaaaagaa gtagagaccc attatcaacc aaagaaatta taaaaaaagt cgagggattt
     3961 cctcgactct ttacatatta tttgttcgtt agttcttaat accagccatt gttaaaccag
     4021 aagtttttag ctctgccaag ccacatagtg tgtttactac tatgtgtcca tgtcaccatg
     4081 aatcgccgaa cgatttaacg agaaagtatg acttttacgt ttatcccaac tcaattatga
     4141 catttttttc aaaagtcaat atatctcact ttttcaacga caagaaagag gctgccaatc
     4201 gaccaacctc ttattctgaa cccatcactc catcactttt tagcttcatt cgctttctta
     4261 gcgactgcaa tctggtattc gacttggtca ttccccttac cggtacaacc atgagcaatt
     4321 gtagtcgctc ctatctgatg cgctatttca accaattttt tagaaatcag agggcggctc
     4381 aaggcagata ccaagggata cttttgttca taataggcat gtgactgatg agccactagc
     4441 acataatctg tagcaaattc gtccttaaca tcaatgacat aagattctac tgccccaacc
     4501 ttaagagcct tatcatggat gaaatctaag tctttccctt cacccacatc catacaaact
     4561 gaaacaacat catagtcttt ctttaaccag gtaatagcaa ctgatgtgtc caaaccgcca
     4621 gaataggcca aaattacttt ttctttactc atgttctttt ccttctttct atttttcaat
     4681 ggatgcttta aaggcatcct caatgagttt gtctaattcc ccagactcct tcaacttttg
     4741 aatggtttta tcgactgcct ctttcaattc cttgctatct tttttcatgg ctaccgcata
     4801 ggaatcatct tgctcttttt caaaattgag gtctgcgatt gctaaatcag gattattttc
     4861 cacaaatccc ttggcaacgg gttcttcaaa aataacggca tccacttgcc ctgattttaa
     4921 atctgtgatt aaattcccat ttttaggcag agatacgagg gaagaatttt gtagcaaatc
     4981 tttcgccatc gtctcttgaa tcgaaccttt ctgcgctccg acctttttct gcgccaaatc
     5041 gttgacagac tgataagtgg ctaaatcaga ttttttgaca atgagtttat tttttgcagt
     5101 atagtaggga gttgaaaaat caaacacctt gctccgttca tctgtcttag aaacacctga
     5161 tatggcaagg tcagcttttc ctgattgaac gctagccagt acattgtcaa aactcatagg
     5221 agatagttcc aattcgacac ctagttctgt tgcgatagcc ttggctaatt cgatatctga
     5281 acccacaatc tgatttttcc catcaaccac tttttgatat tcaaatggag caaaatctgg
     5341 attgagggct acaaccaatt ttcctttgga cttgatggct tcaattccag ccgattgatt
     5401 gttactacaa gcaaatagtt gggggagcat cactaaacca aacatcgtca tcaacacctt
     5461 cttcatctta ttcataacaa agcctccttt atgtttattc ttttttattg tataaataat
     5521 actcctatac tcatcctttg tcaagcctaa attgaaaaaa ttttcaattt gaaac
//
LOCUS       DAVHTH010000085         5554 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.085, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000085 DAVHTH010000000
VERSION     DAVHTH010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5554)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5554)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5554
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.085"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            complement(1..1770)
                     /locus_tag="VVR63_001951"
                     /pseudo
     CDS             complement(1..1770)
                     /locus_tag="VVR63_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050775.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
     gene            complement(1793..2122)
                     /locus_tag="VVR63_001952"
     CDS             complement(1793..2122)
                     /locus_tag="VVR63_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000263054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HEU6129920.1"
                     /translation="MVYRYRTNLKKVFLTDPELHQLNERIAKSNCQNFSVYARKVLLN
                     PNMSFVTINTDTYDQLVFELRRIGNNINQIARAINQSHLISQDQLQELSKGVGELIKE
                     VDKEFQV"
     gene            complement(2132..2491)
                     /locus_tag="VVR63_001953"
     CDS             complement(2132..2491)
                     /locus_tag="VVR63_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6129921.1"
                     /translation="MGQEIKLIRKQFRITRQEEKQIKEMMREQKVDSFSEFLRQNLLK
                     KNYQDRIFESWFSLWQSQKFEQISRDVYEVLVVARENHQVTQEHVSILLTCVQELIAE
                     VNQVQPLSREFREKYMG"
     gene            complement(3323..4479)
                     /locus_tag="VVR63_001954"
                     /pseudo
     CDS             complement(3323..4479)
                     /locus_tag="VVR63_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001213952.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(4507..5268)
                     /locus_tag="VVR63_001955"
     CDS             complement(4507..5268)
                     /locus_tag="VVR63_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HEU6129922.1"
                     /translation="MEIQDYTDSEFKHALARNLRSLTRGKKSSKQPIAILLGGQSGAG
                     KTTIHRIKQKEFQGNIVIIDGDSFRSQHPHYLELQQEYGKDSVEYTKDFAGKMVESLV
                     TKLSSLGYNLLIEGTLRTIDVPKKTAQLLKNKGYEVQLALIATKPELSYLSTLIRYEE
                     LYIINPNQARATPKEHHDFIVNHLVDNTRKLEELAIFERIQIYQRDRSCVYDSKENTT
                     SAADVLQELFFGEWSQVEKEMLQVGEKRLNELLEK"
     gene            complement(5268..5549)
                     /locus_tag="VVR63_001956"
     CDS             complement(5268..5549)
                     /locus_tag="VVR63_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEU6129923.1"
                     /translation="MLNPVEDYELTLKIEIVKERGANLLSRLYRYQDSQGISIDDESN
                     PWILMSDDLSDLIHTNIYLVETFDEIERYSGYLDGIERMLEISEKRMVA"
BASE COUNT         1634 a         1075 c          782 g         2063 t
ORIGIN      
        1 caagttcctg ttgtaatttt aaaatatctg tattgagtcg atctaacatt attgattccg
       61 tcatgttcat ttggtcaaaa tcatacttag ctaattttct accgatctca tcttcacttt
      121 ttagattgat aaacacttcc gccatcttat ttaaggtggc gattttttct tgggtttctt
      181 ctagcttcat atcaatctct gcaatttcta atacaagctc atctttgatt tcttggtatt
      241 gtttgttcgt gttagatagt tcaatcataa gattaatttc agaaatcttc tcttgaagac
      301 tttttaaagt tggtcgtcta taggggagtt tttggctatc gttgctcaat tgtctgatta
      361 aggtcctacc cttgatgaaa caattattat ccatgttttc tttattatag acaaagtaag
      421 aagacgtttc tcgaatgtag actttatatt ttttatgatt ttcttcttcc ataatatcca
      481 attgatagtt gggaatgaaa ataagaccgc tctatttgac accgaaagac accttgatat
      541 agacgccctt atcaactagc ttctctattt ggttctctgc aagttccact tcaaattcac
      601 gaacggtatc tcatttttcc ttaaatgtct taaaggcttc ttaaatgtct taaaggcttc
      661 ctcaatctct tcagtggata ctttatcctt atctcgttct tcttggaaag catggtactg
      721 ttcctgtaaa ttctctaatc cttctgaagc aatgacttcc ttatttttaa aataatcttg
      781 aaaaaatttg acatcatata atttcttatc acttattttt tgatgaccca aacttatctt
      841 ttgattattt tctttcagga taaaagttac atttttttgt tttaagtcaa tggttagatt
      901 caattctttt gcttttgtta ttaactcttc taaagaattg acacggttca acaaaaattc
      961 taaacgactt tcaatctctt gcttagcaaa atgcgttcta aaaaattctt catcatatag
     1021 atctcgtttg ctgagttggc gtcctcgaat aggttttgtc attgctcgat ccgtcatcat
     1081 gaatcgacta tgcttttgac taaaatcaat ctgaacatgc aactgctttg ctttctctaa
     1141 aaaatcatca aactatttag attgctgcat caaaaaataa agacgttgtt tcaattcaaa
     1201 tttatgacta gattccctat attttttata acctcgataa gaataacgtt tctcaataat
     1261 ttttgcacca gccattttag aaatacggtc tgaaatcata cggaggtttc gttccaaggc
     1321 atagttccat atcaactttt tatctgaatt gcggtcaata gcgttgatta ggatgtgatt
     1381 atgaacatga tctttgtctg tgtgagttgc tacgataaac ttaaaacgac ctcctgtcaa
     1441 ttccatcatg gtctcataac caatgcggtt aatttcttca ggtgtcagat tatcttcagg
     1501 agaaaatgat tggatgagat gatgggcatg aatagtttgt tggtgttttt cttgtcggtc
     1561 atttctggac tcgtacaact tgtcgttatt agtaaagtta acattgtaca tttctaccat
     1621 ttctgtatgg ctaggaaaat ctaagtaatt actcatgcca aaatcagata ctaattttag
     1681 attatctgtt ttatctggat tgaggatata tttaatcaaa cgcctacgat atttttttcc
     1741 gtgcgtcgca aagtgtttag taactaccat gaaactcctt cagtcttttc acctacactt
     1801 gaaattcttt gtccacttcc ttaattaact ctccgactcc tttactcaat tcttgtaatt
     1861 ggtcctgaga aatcagatgg ctttgattaa tcgcacgcgc aatttgattg atgttatttc
     1921 caatacgtct caattcaaaa actaactggt cataagtatc agtgttaatc gtgacaaatg
     1981 acatattggg attaagcaaa acttttctgg catagactga aaaattttga caattgctct
     2041 tagcaatccg ttcattcaat tggtgtaatt ctggatcagt tagaaatact tttttgagat
     2101 tggtacgata gcgataaacc attacatcct cctaacccat atatttttca cgaaactcac
     2161 gactgagtgg ctgtacttga ttcacttctg caatcaattc ttgaacgcaa gtcaataaga
     2221 ttgagacgtg ctcttgagtc acttgatgat tttctcttgc gacaaccaga acttcataca
     2281 catctcgact aatctgttca aacttttgag actgccaaag ggagaaccaa ctttcaaaaa
     2341 ttctatcctg ataattcttt ttcaataaat tttgacgaag aaattctgag aaactatcca
     2401 ctttttgttc cctcatcatt tcttttatct gtttttcttc ttgtctcgtg attctaaatt
     2461 gcttacggat taacttaatt tcttgtccca tcttaccatt ctttcaacat tatacttgtc
     2521 tgacaatgta aggctgcctc acattgtcag tacgattcct aaagacctca gtctctcctt
     2581 gttcggtctt tgcgagctca gatattgtgt ccacaatatc ccaaaaatca tatcgccagc
     2641 ctatcaaaac ctaccagttt tgacagctaa cgataagata acttagtggc tccgccccca
     2701 aacccccagg taaaattctt agttggattt ttaaaagttg agaaaagtat agcagaagaa
     2761 atttggggaa gttatcacaa atcaagtaag gactaatctc taacaccact gcatgtaccg
     2821 tcctatattt atgatcagct cccatcgttt acattttcag gtcactgtct tttcatacca
     2881 ggaattagaa ttgacaaatt taattagaga ggtattcatt taattgttca cttcttcgct
     2941 ccatttccat tacagaaatt tcttcaatac tatgtgttca gctgactccc atgattcgtt
     3001 gtactacgtc ctaaacgctc acggaataag ccgtacatct ttcctagttt actctcgtaa
     3061 tttacgtata taggttacga cacctatttg gattttagag ttcctcatcc gctatatatg
     3121 gcttcaagtc acgattctgt ttgtagaacc ttgatttcgc taattccttc ctatcccccc
     3181 tacctcacga tattcaggct taggagtcgc tattggtttc atctgcagca aatatccaca
     3241 gaggacttgg acctcagatg tacactatgc ctgtcggaca aagaaaaaag taggctaaat
     3301 ttctaaccta ctttttctga ctctactctg ataaagccgt ctcatatata gacattttat
     3361 gcttgaagga atcttttcct ccctctaatt gattgatgat atgatttttt atatattttt
     3421 cactaacata tccctgtgat tcaatccatc cgttaactcc atctgactcc ataataacaa
     3481 cttgatctgt catagaattt gttacaattg tagcattatg tgttgctaaa ataatttgac
     3541 gttgagcttt cacatctcta aactgctgaa ctaaatgcct gtaaatataa cgattgtcta
     3601 gattgtcttc aggctgatca ataatcaatg gtctgaagtc tttagaataa tcactatatg
     3661 ctaataaaaa atcaagcatg gctacaactt tttgtcccaa acttaataca ccaacttctt
     3721 tatagagaat atcaagttgt tgcgaaaatt ctttcgagtt aatattaaac tccaaaatcg
     3781 tgtattttct ttagaaaaaa tttttcgttt atatgcacct gataagtgag aacctttttt
     3841 caaaatgtca taactattga aatgagcaat atagttaact attttttgat tattgaaatc
     3901 cttcattata gtcagtgaat gttgataact tccatctttc tcacttataa tattttcact
     3961 taaccattga ttaacccatg attcttgttc ataatcatat atacatacaa tatgcaattt
     4021 atctgctgca ctaatttcta ctccatgtaa aatatgagga tgtatatcat aaatcggata
     4081 atttttcatt atgattgaga ctgccatttg taacttttta atacctttgg tagtattatg
     4141 atcagttact acaactattt ctattccatt ttttatgatt gcctctgcta acataagaaa
     4201 actaatatat tcttttgaac tagaaaaaac aaccttatca aaattactaa aaaaaattgt
     4261 cttatcaact tttattttct tattttcaaa aaatatatca tatagttcat cttcagtaat
     4321 ttttctatat ttcgttgcag tccaattaga aaatagcttg taatcataag aaacaggtgt
     4381 atgcaaatga attaaagtct tgtgaaagct accgaatttc tctttggaat ttgttagttc
     4441 ttgataaaca gactttatct tgttattaaa ccctctcatt tctattctcc taaaaatatc
     4501 aattgtttat ttttcaagta attcattaag tctcttttcc cccacctgca acatctcctt
     4561 ctctacctga ctccactccc caaagaataa ctcttgaaga acatctgctg ctgaagttgt
     4621 attttctttt gaatcatata cacaacttct atctcgttgg taaatttgaa ttctttcaaa
     4681 gatagctagt tcttccaatt ttcgtgtgtt atcaactaga tgatttacaa tgaaatcatg
     4741 atgttctttt ggagttgcgc gtgcttgatt tggattgata atgtacagtt cttcataacg
     4801 gataagagta cttagatacg acaattcagg ctttgtcgca attaaggcca attgtacttc
     4861 atatccctta tttttcaaga gttgtgccgt tttctttgga acatcaattg ttcgtaaagt
     4921 tccctcgatc aaaagattgt atcccaaact actcaatttt gttactaaag actctaccat
     4981 ttttcctgca aaatctttgg tatattctac actgtctttg ccatattctt gctgcagttc
     5041 taaatagtgt ggatgctgag aacgaaaact atcaccatct atgataacaa tatttccttg
     5101 aaattctttc tgtttaatac gatgaattgt agtcttaccg gcaccacttt gacctccaag
     5161 caaaatcgct ataggttgct tactggactt ttttcctctt gtcagtgaac gaagattcct
     5221 tgctaaagca tgtttgaatt cactatcagt ataatcttgg atttccatta agctaccatc
     5281 cgcttttcag atatctctaa catacgttca attccatcca aatagccact atatctctct
     5341 atttcatcaa aagtttctac taaatagata ttcgtatgaa tcaaatcaga aagatcatca
     5401 ctcattaaaa tccaaggatt agattcatca tcaatgctaa ttccctgact atcttgatag
     5461 cgatagagtc gagataatag attagcacct ctttctttca caatttcaat ttttaaagtc
     5521 aattcataat cttcaacagg attgagcatt ttat
//
LOCUS       DAVHTH010000086         5382 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.086, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000086 DAVHTH010000000
VERSION     DAVHTH010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5382)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5382)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5382
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.086"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            72..1331
                     /locus_tag="VVR63_001957"
     CDS             72..1331
                     /locus_tag="VVR63_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRZ/ATZ family protein"
                     /protein_id="HEU6129924.1"
                     /translation="MKVFQHVNIVTCDQNFHVYLDGILAVKDSQIVYVGQDKPAFLEQ
                     AEQIIDYQGAWIMPGLVNCHTHSAMTGLRGIRDDSNLHEWLNDYIWPAESEFTPDMTT
                     NAVKEALTEMLQSGTTTFNDMYNPSGVDIQQIYQVVKTSKMRCYFSPTLFSSETETTA
                     ETISRTRSIIDEILKYKNPNFKVMVAPHSPYSCSRDLLEASLEMAKELNIPLHVHVAE
                     TKEESGIILKRYGKRPLAFLEELGYLDHPSVFAHGVELNEREIERLASSQVAIAHNPI
                     SNLKLASGIAPIIQLQKAGVAVGIATDSVASNNNLDMFEEGRTAALLQKMKSGDASQF
                     PIETALKVLTIEGAKALGMENQIGSLEVGKQADFLVIQPQGKIHLQPQENMLSHLVYA
                     VKSNDVDDVYIAGEQVVKQGQVLTVEL"
     misc_feature    1407..1542
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            1581..2081
                     /locus_tag="VVR63_001958"
     CDS             1581..2081
                     /locus_tag="VVR63_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HEU6129925.1"
                     /translation="MSEAIIAKKAELVDVVAEKMKAAASIVVVDARGLTVEQDTVLRR
                     ELRGSEVEYKVIKNSILRRAAEKAGLEDLASVFVGPSAVAFSNEDVIAPAKILNDFSK
                     NAEALEIKGGAIEGAVASKEEILALATLPNREGLLSMLLSVLQAPVRNVALAVKAVAE
                     SKEDAA"
     gene            2157..2525
                     /gene="rplL"
                     /locus_tag="VVR63_001959"
     CDS             2157..2525
                     /gene="rplL"
                     /locus_tag="VVR63_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HEU6129926.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     DAADAGAAKDSFDVELTSAGDKKVGVIKVVREITGLGLKEAKELVDGAPALVKEGVAT
                     AEAEEIKAKLEEAGASVTLK"
     gene            2727..2900
                     /locus_tag="VVR63_001960"
     CDS             2727..2900
                     /locus_tag="VVR63_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000159601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6129927.1"
                     /translation="MTKELQSSRYIVISFLVREMGIDIVEAISLMAELEKSGLVRLES
                     SGDLILKELGGAL"
     gene            2897..3676
                     /locus_tag="VVR63_001961"
     CDS             2897..3676
                     /locus_tag="VVR63_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HEU6129928.1"
                     /translation="MKRITANQYQTSERYYKLPKILFEDEKYMDMKLEVKVAYSILKD
                     RLELSLSRGWIDEEGAVYLVFSNSKLMKLLGCSKSKLLSIKKILKEYDLIDEVQQSSS
                     EKGRLANKIYLGELSSTPVASSNRPSVKKKIGQVENETAPVSHSAPSETEVSETKYSE
                     TDSLFSEDEEERYTQPILKRKVEKVTKYDQDYIWGLVQDQFRREGFSETASEIAMTDF
                     ERIYQYALDNVRFVRRAEVLAEFVFNGLYSVWNNRVRKGGG"
     gene            3775..5133
                     /gene="dcm"
                     /locus_tag="VVR63_001962"
     CDS             3775..5133
                     /gene="dcm"
                     /locus_tag="VVR63_001962"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014947343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
                     /protein_id="HEU6129929.1"
                     /translation="MRFIDLFSGIGGFRLGMESVGHECIGFCEIDKFARESYKSIFQT
                     EGEIEFHDIRDVSDDEFKKLRGKVDIICGGFPCQAFSIAGRRLGFEDIRGTLFFEIAR
                     AAKQIQPRFLFLENVKGLLNHDKGRTFTTILTTLDELGFDVEWQVLNSKDFGVPQNRE
                     RVFIIGHSRKKGIRLLFPFRREGQATNSETLKTLGNLNPSKSGMSGKVYYSEGLAPTL
                     VRGKGEGFKIAIPCMTPDRLDKRQNGRRFKENQEPMFTLNTQDRHGIVVVGDLPTSFK
                     ETGRVYGSEGLSPTLTTMQGGDKIPKILIPEPIQFLKVREATKKGYAQAEIGDSINLE
                     RPSSQYRRGRVGKGIANTLTTSGQMGVVVASYEGEDKQVYHVAGILIDGQFYRLRIRR
                     ITPKECFRLQGFPDWAFEAARRVSSNSQLYKQAGNSVTVPVIAAIAKKLKEIEEKDES
                     IK"
     gene            5117..>5382
                     /locus_tag="VVR63_001963"
     CDS             5117..>5382
                     /locus_tag="VVR63_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6129930.1"
                     /translation="MKALNKESILDCDELETELHDAEIKQLDEQLFLIPNYPCEFEVT
                     FLDDYHKKHNYPLFYESYLQNVMEFLESQDIKNGVDAFVDDHQNL"
BASE COUNT         1771 a          899 c         1178 g         1534 t
ORIGIN      
        1 acacctacgg caaagtgaat ctgaagtggt ttgaagagag tacaacttgt cttttaaaaa
       61 aggagtctat aatgaaagtc tttcagcatg taaatatcgt gacttgtgat caaaatttcc
      121 atgtttatct tgatggaatc ttagcagtca aggattctca aatcgtctat gtcggtcaag
      181 ataagccagc gtttttagaa caagctgagc agattataga ctatcaggga gcttggatta
      241 tgcctggttt ggtcaattgt cacacccatt ctgcaatgac aggtctgaga gggatccgag
      301 atgacagcaa tctccatgaa tggctcaatg actatatctg gccagcagaa tctgagttta
      361 ctcccgacat gactaccaat gcggtcaaag aagccttgac agagatgctc cagtcaggaa
      421 caacaacctt taacgatatg tataatccca gtggtgtgga tatccagcaa atttatcagg
      481 tggtgaaaac ttccaagatg cgttgttatt tttctccgac tctcttttct tcagagacag
      541 aaacaactgc tgagactata agcagaactc gatccatcat agacgaaatc ttaaaatata
      601 aaaatccaaa tttcaaggtt atggtagcac ctcattctcc gtatagctgc agtagagact
      661 tgctggaagc gagtttggaa atggcaaaag agctaaatat tccgctccat gtccatgtgg
      721 cggagaccaa ggaggagtca ggaattatcc tcaaacgata cggcaaacgc ccccttgctt
      781 ttcttgaaga actgggttat ttagatcatc cgtccgtatt tgctcacggg gtcgaattaa
      841 acgagagaga aattgaacgc ttggcatctt ctcaagtggc tatcgcccac aatcctatca
      901 gtaacctcaa actggcatca ggaattgctc caattatcca gctccaaaaa gcgggagtag
      961 cagtcggaat tgcgactgac tcggttgctt ccaataacaa tctagatatg tttgaggaag
     1021 gaaggactgc agctcttctt cagaagatga aaagtgggga tgccagccag tttccaatcg
     1081 aaacagctct caaggtactg acaatcgaag gggctaaggc ccttggaatg gaaaatcaga
     1141 taggaagtct ggaagtcggc aagcaagcag attttctggt cattcaacca caagggaaaa
     1201 ttcatctcca acctcaggaa aatatgctgt ctcacctggt ttatgcagtt aaatctaatg
     1261 atgtagatga tgtttatatc gccggagaac aggttgttaa gcaaggtcaa gtcctgacag
     1321 tagaacttta aaagaaaaat cacgaaaaat tttaaaaaaa gtttgcaaaa atcttgcatt
     1381 ctttttttga ctatgctata cttatatacg gtttaaaaaa actgcctaag acagtagggg
     1441 agctcgactc ataaatatcc taccgaggac aagacgtatc atgtaaaaag aagcgtattg
     1501 tactttcgtg tctaggtttg ggcgcgtttt tctttttgaa aaattcccca agcaaaataa
     1561 ttacggaggt gaacacacta atgagtgaag caattattgc taaaaaagcg gaactagttg
     1621 acgtagtagc tgaaaaaatg aaagctgctg catctatcgt cgttgtagac gctcgtggtt
     1681 tgacagttga gcaagataca gttcttcgtc gtgagcttcg tggaagcgaa gttgagtata
     1741 aagttattaa aaactcaatc ttgcgtcgtg cagctgaaaa agctggtctt gaagatcttg
     1801 catctgtatt tgttggacca tctgcagtag cattttctaa tgaagatgtt atcgcaccag
     1861 cgaaaatctt gaatgacttt tctaaaaacg ctgaagcact tgaaattaaa ggtggtgcaa
     1921 tcgaaggcgc tgtcgcatct aaagaagaga ttcttgcact tgcaactctt ccaaaccgcg
     1981 aaggacttct ttctatgctc ctttctgtac ttcaagcgcc agtgcgcaac gttgctcttg
     2041 cagtcaaagc ggttgcagaa agcaaagaag acgcggctta atcttaagct acacagcgta
     2101 gcctagctac gaaaaaaact attataaaat ttaaaactta tttggaggaa ataacaatgg
     2161 cattgaacat tgaaaacatt attgctgaaa ttaaagaagc ttcaatcctt gaattgaacg
     2221 accttgtaaa agctatcgaa gaagaatttg gtgtaactgc agctgctcct gtagctgttg
     2281 ctgcagctga tgcagctgat gctggtgctg ctaaagattc attcgacgtt gaattgacat
     2341 ctgcaggcga caaaaaagtt ggcgttatca aagttgtacg tgaaatcact ggtcttggtc
     2401 ttaaagaagc taaagaactt gttgacggtg caccagcact tgttaaagaa ggcgttgcaa
     2461 ctgcagaagc tgaagaaatc aaagctaaat tggaagaagc tggagcttca gttactctta
     2521 aataagaggc atataccaat tagaattcgg aatactatag tatcagcctt ttagaatcgt
     2581 gaacacattt tagaaactga taaattaatt tagtttcctg ccaaaaaccc taccaaaaat
     2641 taatttggca gggtttttct ttttaataaa aatattttgg agaacagttg aatattgttc
     2701 tccttttttt attttctgga ggaaaaatga caaaagaatt acaatcatca cgctatattg
     2761 tcatttcatt tttagtacgt gaaatgggaa ttgacattgt tgaagccatc tctcttatgg
     2821 ctgaattaga aaaaagtggc ttggttcgat tggaatcaag tggagattta atactcaaag
     2881 aacttggagg agcgctatga aacgaattac cgcaaatcaa tatcaaactt cagaacggta
     2941 ttataaatta cctaaaattc tttttgagga tgagaaatat atggatatga aactagaagt
     3001 aaaggtggct tattctattt taaaagatcg tttagaatta tctctcagtc gtggttggat
     3061 agatgaagaa ggagcggttt atttagtatt ttctaactct aaactgatga aactgttagg
     3121 ttgttcgaag tcaaaattac tgtctataaa aaaaattctt aaagaatatg acttaattga
     3181 tgaagtccaa cagtcttcca gtgagaaagg gaggctagct aataagattt atttagggga
     3241 gttgtcttct accccagtag ctagttcaaa caggcctagt gttaaaaaaa aaatagggca
     3301 ggttgaaaat gaaactgccc ccgtctcaca ttcagcccct agtgagactg aagttagtga
     3361 gactaaatat agtgagactg attctttatt tagtgaggat gaggaggaga ggtatactca
     3421 acctatcttg aaaagaaaag tagaaaaggt cacaaaatat gatcaagatt atatttgggg
     3481 attggtacaa gatcaattta gacgagaagg tttttctgaa acagccagtg aaattgctat
     3541 gactgatttt gagagaatct atcagtatgc tcttgacaat gttcgctttg ttagaagagc
     3601 ggaagtactt gctgaatttg tatttaacgg cttgtattct gtttggaata atcgtgttag
     3661 aaaaggaggt ggttaaatgt cgccaatcga gtggatatta gttatgctca ttgtcatttc
     3721 aagtggtgtg acactttgga cattgatagt tgatcagaaa ggggtaatca agaaatgaga
     3781 tttattgatt tattttcagg tatcggtggt tttcgacttg gaatggaaag tgtaggacac
     3841 gagtgtattg gattttgtga gattgataaa tttgctagag aatcttataa gtccattttt
     3901 caaacggaag gagaaataga atttcatgac atacgagatg tttcagatga cgaatttaaa
     3961 aaacttagag ggaaagtcga tatcatctgt gggggatttc cttgtcaagc attttcaatc
     4021 gcaggaagac gattgggatt tgaagatatt agaggaactt tgttctttga aattgctcgg
     4081 gcggccaaac aaatccaacc acgttttctt tttcttgaaa atgttaaagg tctactcaat
     4141 cacgataagg gacggacgtt caccacaatc cttaccacac ttgatgagtt ggggtttgat
     4201 gttgaatggc aggtgcttaa cagtaaggat tttggcgttc cccaaaacag agagagggtg
     4261 tttattatcg gacattctag aaagaaaggt atcagactct tatttccttt cagacgagaa
     4321 ggtcaagcaa ctaactctga gactttaaaa acattaggaa atttgaatcc atcaaaaagt
     4381 ggaatgagcg gtaaagttta ttattcagaa ggtcttgcgc caaccttagt tcgtgggaaa
     4441 ggagaaggat ttaagattgc gattccttgt atgacaccag atagattaga caagagacaa
     4501 aatggtagac gctttaagga aaaccaagag ccaatgttta ctttaaatac tcaggatcgt
     4561 catggcattg tcgttgttgg agatttaccg actagcttta aggagaccgg tcgtgtctat
     4621 ggaagtgagg ggttatctcc aacactgact acgatgcaag gtggagataa aatccccaaa
     4681 atactgattc cagaaccaat tcaatttcta aaagtccggg aagcaacgaa aaaaggatac
     4741 gctcaagcag aaataggaga ttcaatcaat ttggaaagac caagttctca gtatcgtcgt
     4801 ggtagagttg gaaaaggtat agctaatacg ttaacaacta gtggacaaat gggagtagta
     4861 gttgctagtt atgaaggaga agataaacaa gtttatcatg tagccggtat attaatagat
     4921 ggacaatttt accgtctgag gatacgacga atcactccta aagagtgttt tcgcttgcag
     4981 ggctttcctg attgggcttt tgaagctgct agaagagtct ctagtaatag tcagctctat
     5041 aaacaagctg gtaatagtgt aaccgttcct gtgattgccg caatcgcaaa gaaattaaaa
     5101 gaaatagagg aaaaagatga aagcattaaa taaagaatca atactagatt gtgatgaatt
     5161 agaaacagaa ttacatgatg cagaaatcaa acagctggat gaacaattat ttttgatacc
     5221 caattatcca tgtgagtttg aagtaacatt tttagatgat taccataaaa aacacaacta
     5281 cccactattt tacgagtcct atcttcaaaa cgtgatggaa ttccttgaaa gtcaagacat
     5341 aaagaatggg gttgatgcct ttgtagatga tcatcaaaat ct
//
LOCUS       DAVHTH010000087         5309 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.087, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000087 DAVHTH010000000
VERSION     DAVHTH010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5309)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5309)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5309
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.087"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            <1..123
                     /locus_tag="VVR63_001964"
     CDS             <1..123
                     /locus_tag="VVR63_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU6129931.1"
                     /translation="LIKLIKRNAFGFRNFENFKKRIFIALNIKKERTKFVLSRA"
     gene            complement(384..1358)
                     /gene="pta"
                     /locus_tag="VVR63_001965"
     CDS             complement(384..1358)
                     /gene="pta"
                     /locus_tag="VVR63_001965"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HEU6129932.1"
                     /translation="MEVFESLKANLVGKNARIVLPEGEEPRILQATKRLVKETEVIPV
                     LLGNPEKIKIYLEIEGIMDGYEVIDPQHYPQFEEMVSALVERRKGKMTEEDVRKVLVE
                     DVNYFGVMLVYLGLVDGMVSGAIHSTASTVRPALQIIKTRPNVTRTSGAFLMVRGTER
                     YLFGDCAININPDAEALAEIAINSAITAKMFGIEPKIAMLSYSTKGSGFGESVDKVVE
                     ATKIAHDLRPDLEIDGELQFDAAFVPETAALKAPGSTVAGQANVFIFPGIEAGNIGYK
                     MAERLGGFAAVGPVLQGLNKPVNDLSRGCNADDVYKLTLITAAQAVHQ"
     gene            complement(1402..2298)
                     /locus_tag="VVR63_001966"
     CDS             complement(1402..2298)
                     /locus_tag="VVR63_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEU6129933.1"
                     /translation="MRFEFIADEHVKVKTFLKKHEVSKGLLAKIKFRGGAILVNNQPQ
                     NATYLLDVGDYVTIDIPAEKGFETLEAIELPLDILYEDDHFLVLNKPYGVASIPSVNH
                     SNTIANFIKGYYVKQNYENQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQKKSIE
                     KRYFALVKGDGHLEPEGEIIAPIARDEDSIITRRVAKGGKYAHTSYKIVASYGNIHLV
                     YIHLHTGRTHQIRVHFSHIGFPLLGDDLYGGSLEDGIQRQALHCHYLSFYHPFLEQDL
                     QLESPLPDDFSNLITQLSTNTL"
     gene            complement(2295..3113)
                     /locus_tag="VVR63_001967"
     CDS             complement(2295..3113)
                     /locus_tag="VVR63_001967"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HEU6129934.1"
                     /translation="MKNTGKRIDLIANRKPQSQRVLYELRDRLKRNQFILNDTNPDIV
                     ISIGGDGMLLSAFHKYENQLEKVRFIGLHTGHLGFYTDYRDFELDKLVTNLQLDTGAR
                     VSYPVLNVKVFLENGEVKIFRALNEASIRRSDRTMVADIVINGVPFERFRGDGLTVST
                     PTGSTAYNKSLGGAVLHPTIEALQLTEIASLNNRVYRTLGSSIIVPKKDKIELIPTRN
                     DYHTISVDNSVYSFRNIERIEYQIAHHKIHFVATPSHTSFWNRVKDAFIGEVDE"
     gene            complement(3097..3768)
                     /locus_tag="VVR63_001968"
     CDS             complement(3097..3768)
                     /locus_tag="VVR63_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HEU6129935.1"
                     /translation="MTLEWEEFLDPYIQAVGELKIKLRGIRKQYRKQNKHSPIEFVTG
                     RVKPIESIKEKMARRGITYATLEHDLQDIAGLRVMVQFVDDVKEVVDILHKRQDMRII
                     QERDYITHRKASGYRSYHVVVEYTVDTINGVKTILAEIQIRTLAMNFWATIEHSLNYK
                     YQGDFPDEIKKRLEITARIAHQLDEEMGEIRDDIQEAQALFDPLSRKLNDGVGNSDDT
                     DEEYR"
     gene            3896..4465
                     /locus_tag="VVR63_001969"
     CDS             3896..4465
                     /locus_tag="VVR63_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HEU6129936.1"
                     /translation="MKHLEIELKTLLKKDEYNRLKDQFTGVTPVLQTNYYIDTPDFEL
                     REKKVAMRIRTFEDWAELTLKVPQSVGNMEYNQKLQLKDAENYLSKEELPQGLVLDEL
                     AKHGIQSKNWQVLGCLTTLRYEMKTAIGLMALDQSRYFDITDYELELEVENHEQGKQD
                     FRQFLEKNQISYQKAPSKLVRFVKSMKNS"
     gene            4578..>5309
                     /locus_tag="VVR63_001970"
     CDS             4578..>5309
                     /locus_tag="VVR63_001970"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEU6129937.1"
                     /translation="MSDRKNMKLFALNSNQEIAQKIAQAVGVPLGKLSSRQFSDGEIQ
                     VNIEESVRGYDVYIIQSTSFPVNNHLMELLIMVDACVRASAHSINVVLPYFGYARQDR
                     IACPREPLTAKLVANMLVKAGVDRILTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCD
                     KGLLGSDVVVVSPKNSGVKRARSLAEYLDAPIAIIDYPQDDATRNEGYIIGDVEGKKA
                     ILIDDILNTGRTFSEASKIVEREGAT"
BASE COUNT         1634 a         1129 c          989 g         1557 t
ORIGIN      
        1 ctcatcaaac ttatcaagcg caatgccttt ggttttcgga actttgaaaa cttcaaaaaa
       61 cggattttta tcgctctgaa tatcaaaaaa gaaaggacaa aatttgtcct ttctcgagct
      121 tagctgactt caacccacta cagttgacaa agagccaaaa aattctcttt tcatactcat
      181 ttaaaatcaa aaagggaatt tatcgtttta cggatatgta tattacagat ttctataggt
      241 cgtgtataga caggatatca tcgcttggaa gttttccttt ttgacaccaa tcagtaattt
      301 agttctcagg aattaatggc agtgcttttc gtacatagtt tcataactac agtatagcat
      361 agtatatcac tttatagttt tcactattga tgaactgctt gagctgctgt gatgagggtc
      421 aacttgtaaa catcatctgc attacatcca cgagaaagat cattaactgg cttgtttaaa
      481 ccttgcaaaa caggtcctac agccgcaaag ccacccaggc gttcagccat cttgtaaccg
      541 atatttcctg cctcgatacc tgggaagatg aagacatttg cttgaccagc tactgtactt
      601 cccggagctt tcagagctgc agtttcggga acaaaggccg catcaaattg caactcacca
      661 tcgatttcaa ggtcaggacg caagtcgtga gcaattttag ttgcttcaac gaccttatca
      721 acgctttcac caaaccctga acctttagta gaatagctca acatggcaat tttaggttcg
      781 atgccaaaca tcttagctgt gattgctgag ttgatggcaa tttcagccaa ggcttctgca
      841 tctggattga tattaatggc acagtctcca aataggtaac gttccgtacc acgaaccatg
      901 aggaaggctc ctgaagtacg agttacattt ggacgagttt tgatgatttg tagagctggg
      961 cgaactgttg aagctgttga gtgaatcgct cctgacacca ttccatcaac caagcccaag
     1021 taaaccaaca tcacaccaaa gtagttgaca tcttcaacca aaaccttgcg tacatcttct
     1081 tcagtcattt tgcccttgcg acgctccacc aaggcagaaa ccatttcttc aaattgagga
     1141 taatgttgag ggtcgatgac ctcataacca tccatgattc cttcaatttc aagataaatt
     1201 ttaatttttt caggatttcc aagcaaaaca ggaatcactt ctgtttcttt tactaagcgt
     1261 tttgttgctt gaagaatacg aggctcttcc ccttcaggga gaacgatacg agcattttta
     1321 ccaacaaggt tggctttgag actttcaaaa acttccatga gttttctcct ttaagataat
     1381 aattatactc tgagacagtt tttatagagt attagttgat aactgggtaa taaggttact
     1441 gaaatcatcc ggcaagggac tttctaactg caagtcttgc tctaaaaatg gatgataaaa
     1501 ggataggtaa tggcaatgca gagcctgacg ttgaatacca tcttccagac taccaccata
     1561 caaatcatct cccagcaaag gaaaaccgat atgagaaaaa tggactcgga tttgatgggt
     1621 tcgaccagtg tgcaggtgaa tatagaccaa gtgaatattt ccataagaag ctacaatctt
     1681 gtatgaagta tgggcatact ttccgccttt agccactcgt ctggtaataa tggaatcttc
     1741 atcacgcgca atcggagcaa taatttcccc ttctggttcc aaatgtccat ctcccttaac
     1801 caaagcaaag tagcgtttct cgatagattt cttctgcaac tgcttgtcta atcgtgcatg
     1861 ggcataaccg tgcttggcaa agagcatcaa gccagaagtg tccctatcta gtctggtaac
     1921 aatgtgaacc tgctgatttt cataattttg cttgacatag taacccttga taaaattggc
     1981 aatggtatta gagtgattaa cactaggaat agaagccact ccatagggtt tattcaagac
     2041 tagaaagtgg tcatcctcat agagaatatc taatggaagc tcaatagcct ccaaggtttc
     2101 aaagcctttc tcagcgggaa tgtcaatggt aacgtagtct ccaacgtcca atagatacgt
     2161 tgcattttgc ggttgattat tgaccagaat agctccacct cgaaacttaa tcttggccag
     2221 caatccctta gaaacctcgt gcttttttaa gaaggtctta accttgacat gttcatctgc
     2281 gataaattca aacctcattc atccacctca ccgataaagg catccttaac acggttccag
     2341 aaactggtat ggctaggagt cgcgacaaag tgaatcttat gatgggcgat ttgatactca
     2401 atacgctcaa tattacggaa agaataaacg ctattgtcaa ccgaaatagt atgataatcg
     2461 tttcttgttg gaataagttc aatcttatcc ttcttaggca caataatgga agagcccagt
     2521 gttcgataga cacgattatt aaggctggca atttccgtta attgcaaagc ttcaatggta
     2581 gggtgtaaaa cagcaccgcc aagagacttg ttataggcag tactaccagt cggtgtcgaa
     2641 actgttagcc cgtctccacg aaaacgttca aagggaacac catttattac aatatctgcc
     2701 accatggttc gatcagacct gcggatgctg gcttcgttga gtgctctgaa aatcttaact
     2761 tcaccatttt caagaaagac cttcacattc agaacagggt aagaaaccct tgccccagta
     2821 tctagctgca aattagtcac tagcttgtcc aactcaaaat cacgataatc tgtatagaag
     2881 cccaaatgtc cagtgtgaag accgataaag cggaccttct caagctgatt ttcgtactta
     2941 tgaaaggccg acaagagcat accatccccg ccaatggaaa tgacaatatc cggattggta
     3001 tcattgagta taaactgatt tctcttcaaa cgatctcgca attcatacaa aaccctttga
     3061 ctctgcggtt ttctattggc tatcagatca attcgtttac ctgtattctt catctgtatc
     3121 gtcactgttt cctacaccgt catttaattt tctactcaaa ggatcaaaaa gtgcctgagc
     3181 ttcttggata tcatcacgaa tttcacccat ttcttcatcc aactgatggg cgattctagc
     3241 tgtaatttcc agtcgcttct taatctcatc tgggaaatcc ccttggtact tgtagttgag
     3301 agaatgttct atcgttgccc agaaattcat ggccaaagta cgaatttgaa tttctgccaa
     3361 aatagtctta actccattga tggtatcaac cgtatattct actaccacat gataggaacg
     3421 atagcctgat gcttttctat gagtaatgta atctcgctcc tgtatgattc gcatatcctg
     3481 acgcttgtgc aaaatatcca ctacttcctt gacgtcatct acaaactgaa ccatcacacg
     3541 taagccagca atatcctgca aatcgtgttc caaggtcgca taagtaatgc cacgacgagc
     3601 cattttttct ttgatgctct caattggctt aactcgaccg gtcacaaact caattggaga
     3661 atgcttattt tgcttacgat attgcttacg aataccacga agtttaatct ttaactcacc
     3721 aacagcttga atgtaaggat ctagaaattc ttcccattct aaggtcatat attctccctt
     3781 gttctcatat tatccgtcaa aaatatcttt gattttttct ccagattcat atacaataaa
     3841 tacaatgctt attataccat aaatccgctt tcaacgataa aaaaaggtaa gaaaaatgaa
     3901 acatttagaa attgaattga aaacactatt gaaaaaagat gaatacaatc gtctaaaaga
     3961 ccagttcaca ggtgtcactc ctgttcttca aacaaattac tacatcgaca cgcctgattt
     4021 tgaactgcga gaaaagaaag tcgctatgcg cattcgaacc tttgaagact gggctgagtt
     4081 gacactcaaa gtcccgcaga gtgttggaaa catggaatac aaccaaaaat tgcaactaaa
     4141 agatgctgag aactatctga gtaaggaaga acttcctcaa gggctagtac tggatgaatt
     4201 ggcgaaacat ggtatccaaa gtaagaactg gcaggttctt ggttgtctaa caacgcttcg
     4261 ctatgaaatg aaaacagcta ttggtctcat ggcactggat cagagccgat actttgatat
     4321 aacagattac gaattggagc ttgaagtgga aaatcatgag caaggcaaac aggatttccg
     4381 acaattttta gagaaaaatc agatttccta ccaaaaagct ccttcaaaat tggttcgatt
     4441 tgtcaaaagt atgaaaaata gctgaaataa tctccatttt ttggtaaaat agaaaagata
     4501 aaaatacaca aatcccagtt catatatgta aggtaaatat aactaggatt tataaagttt
     4561 acagaggacg gtctataatg tcagatagaa aaaacatgaa acttttcgca ctcaactcta
     4621 accaagagat tgcacaaaaa attgcccaag ctgttggtgt cccacttgga aaactatcat
     4681 cacgtcaatt ttcagacgga gaaatccaag taaatatcga agaaagtgtc cgtggttatg
     4741 atgtttacat catccaatca acaagtttcc ctgtcaacaa ccacctaatg gaattgttaa
     4801 tcatggtcga tgcttgtgtg cgtgcaagtg cccacagtat caacgttgtc cttccatatt
     4861 ttggctatgc acgtcaagac cgcattgctt gtcctcgtga gccacttaca gcaaaactag
     4921 ttgccaatat gctggttaag gctggagttg atcgtatcct gactcttgat ttgcatgccg
     4981 ttcaggttca aggtttcttt gatattccag tggataatct tttcactgtt cccctattcg
     5041 caaaacatta ctgcgataaa ggattgcttg gttcagatgt tgttgtcgtt agccctaaaa
     5101 attcaggtgt caaacgtgcg cgtagcctgg ctgaatatct tgatgctcct atcgccatta
     5161 tcgactaccc tcaagacgat gcaactcgta acgaaggtta tattattggt gatgttgaag
     5221 gtaagaaagc tatcttgatt gatgatattt taaatacagg acgtaccttc tctgaagctt
     5281 ctaaaatcgt tgaacgtgaa ggagctaca
//
LOCUS       DAVHTH010000088         5103 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.088, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000088 DAVHTH010000000
VERSION     DAVHTH010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5103)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5103)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5103
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.088"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            173..1456
                     /locus_tag="VVR63_001971"
     CDS             173..1456
                     /locus_tag="VVR63_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007554578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HEU6129938.1"
                     /translation="MKQESTVDLLLDVDQRPSDGKGILLSFQHVFAMFGATILVPLIL
                     GMPVSVALFASGVGTLIYMIATGFKVPVYLGSSFAFITAMSLAMKEMGGDVSAAQTGV
                     ILTGLVYVLVATSIRFVGTKWIDKLLPPIIIGPMIIVIGLGLAGSAVTNAGLVADGNW
                     KNALVAVVTFLIAAFINTKGKGFLRIIPFLFAIIGGYLFALTLGLVDFTPVLKANWFE
                     IPGFYLPFSTGGAFKEYNLYFGPEAIAILPIAIVTISEHIGDHTVLGQICGRQFLKEP
                     GLHRTLIGDGIATSVSAFLGGPANTTYGENTGVIGMTRIASVSVIRNAAFIAIALSFL
                     GKFTALISTIPNAVLGGMSILLYGVIASNGLKVLIKERVDFAQMRNLIIASAMLVLGL
                     GGAILKLGPVTLSGTALSAMTGIILNLILPYENKD"
     gene            complement(1651..3222)
                     /gene="ffh"
                     /locus_tag="VVR63_001972"
     CDS             complement(1651..3222)
                     /gene="ffh"
                     /locus_tag="VVR63_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HEU6129939.1"
                     /translation="MAFESLTERLQNVFKNLRKKGKISESDVQEATKEIRLALLEADV
                     ALPVVKDFIKKVRERAVGHEVIDTLNPAQQIIKIVDEELTAVLGSDTAEIIKSPKIPT
                     IIMMVGLQGAGKTTFAGKLANKLKKEENARPLMIAADIYRPAAIDQLKTLGQQIDVPV
                     FALGTEVPAVEIVRQGLEQAQTNHNDYVLIDTAGRLQIDELLMNELRDVKALAQPNEI
                     LLVVDAMIGQEAANVAREFNAQLEVTGVILTKIDGDTRGGAALSVRHITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDMLTLIEKASQEYDEQKALEMAEKMRENTFDFNDF
                     IDQLDQVQNMGPMEDLLKMIPGMANNPALQNMKVDERQIARKRAIVSSMTPEERENPD
                     LLNPSRRRRIAAGSGNTFVEVNKFIKDFNQAKQLMQGVMSGDMNKMMKQMGINPNNLP
                     KNMPNMGGMDMSALEGMMGQGGMPDLSALGGAGMPDMSQMFGGGLKGKIGEFAMKQSM
                     KRMANKMKKAKKKRK"
     gene            complement(3234..3566)
                     /locus_tag="VVR63_001973"
     CDS             complement(3234..3566)
                     /locus_tag="VVR63_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009660419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HEU6129940.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEDYEMKLHMYSDYIVRSQIFDQILERYPKDNFLQEQIEI
                     LTSIDNRE"
     gene            complement(3657..4034)
                     /locus_tag="VVR63_001974"
     CDS             complement(3657..4034)
                     /locus_tag="VVR63_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HEU6129941.1"
                     /translation="MKIRMRNTIQFDEQLEVIDQLYDVEVHEKGDYSYLLFYNEEKEK
                     VVIKFHGQELMMSRFSNPKTIMRFLKDSDSLAYIPTPMGMQEFIIQTSHYQVDRQKIE
                     LDYQLQNQEGHPFASYQLEITWG"
     gene            4106..>5103
                     /locus_tag="VVR63_001975"
     CDS             4106..>5103
                     /locus_tag="VVR63_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEU6129942.1"
                     /translation="MNEKVFRDPVHNYIHVNNQIIYDLINTKEFQRLRRIKQLGTSSY
                     TFHGGEHSRFSHCLGVYEIARRITEIFEEKYPEEWNPAESLLTMTAALLHDLGHGAYS
                     HTFENLFDTDHEAITQEIIQNPETEIHQVLLQVAPDFPEKVASVIDHTYPNKQVVQLI
                     SSQIDADRMDYLLRDSYFTGASYGEFDLTRILRVIRPIENGIAFQRNGMHAIEDYVLS
                     RYQMYMQVYFHPATRAMEVLLQNLLKRAKELYPEDKDFFARTSPHLLPFFEKNVTLTD
                     YLALDDGVMNTYFQLWMTSPDKILADLSHRFVNRKVFKSITFSQEDQDQLASMRKLV"
BASE COUNT         1377 a         1191 c          948 g         1587 t
ORIGIN      
        1 ttttttctgc tatactatcc taagcaaagg tttttaatgt catcccgtga ggtgacgaag
       61 acgcagaaat atttgaaact ctttaaagtc tagattttag agaagtctta ctctgagggc
      121 ctattgctgt aaaataatgg gctcttttct gatgcccaaa agtgaggttt atatgaaaca
      181 agaatcaact gttgatttgt tactagacgt tgaccaacgt ccttcggatg gaaaaggaat
      241 tctccttagc ttccaacacg ttttcgccat gtttggtgcg accatcttgg taccattgat
      301 tttgggaatg cctgtatctg ttgccctttt tgcttcaggt gttggaacac tcatctacat
      361 gattgctact ggttttaaag ttccagttta tctaggttct tcatttgcct ttatcacagc
      421 tatgtcactg gctatgaaag aaatgggggg ggatgtatct gctgcccaaa caggggttat
      481 cttgactggt ttggtctatg tccttgttgc taccagcatc cgatttgtag gaacaaaatg
      541 gattgataaa ctcttgccac caatcattat cggtcctatg atcatcgtta tcggtcttgg
      601 acttgcaggt tcagctgtta ccaatgcagg tcttgtagca gacggaaatt ggaaaaatgc
      661 tctggtagcc gttgttactt tcctaattgc tgcctttatc aatacaaaag gaaaaggctt
      721 cctacgaatc attccattcc tctttgccat tatcggtggt taccttttcg cactaactct
      781 tggcttggtt gactttacac cagttcttaa agccaactgg ttcgaaattc ctggtttcta
      841 cttgccattt agcacaggtg gtgcctttaa agagtacaat ctttactttg gtccagaagc
      901 catcgctatc ttgccaatcg ctatcgtaac aatttctgaa catatcggag accatactgt
      961 tttgggtcaa atctgtggcc gtcaattctt aaaagaacca ggtcttcacc gtactcttat
     1021 tggtgacggt atcgcaactt ctgtttctgc cttccttggt ggaccagcca atacaactta
     1081 cggagaaaat acaggggtta tcggtatgac tcgtatcgct tctgtctcag ttatccgtaa
     1141 cgctgccttc atcgcgattg ccctcagctt ccttggtaaa ttcactgcct tgatttcaac
     1201 tattccaaac gctgtacttg gtggtatgtc aatccttctc tatggggtta tcgccagcaa
     1261 tggtttgaaa gtcttgatta aagaacgtgt tgatttcgct caaatgcgaa acctcatcat
     1321 cgcaagtgct atgttggttc ttggacttgg aggagctatc cttaaacttg gtccagttac
     1381 actttcaggt actgcccttt cagccatgac aggaatcatc ttgaacttga tcttgccata
     1441 cgaaaataaa gactaagagt ctaaatacac ctaatccact cagacagctg agtggatttt
     1501 tcgtatatca taataaaagt gtcttaacaa aattattaaa atcaaaaaac gtataatatc
     1561 agatattcta aaaccttgat actgtacgtt ttatcataga aatttttact ttattttctc
     1621 atcaaatgag atttgcatca atctcttgtc ttacttgcgt ttcttcttcg ctttcttcat
     1681 tttgttagcc atacgtttca tggactgttt catggcaaat tcaccaattt tacctttcaa
     1741 accgccacca aacatctggc tcatatctgg cattcctgct cctccgagag ctgataagtc
     1801 aggcataccg ccttgtccca tcattccttc aagggcagac atatccattc ctcccatatt
     1861 tggcatattt ttaggaaggt tatttggatt aatccccatt tgcttcatca ttttattcat
     1921 atccccagac ataacaccct gcatgagctg tttagcctgg ttaaagtcct tgataaattt
     1981 attgacttcg acgaatgtat ttccagaacc agcagcaata cgacggcgac ggcttggatt
     2041 taacaaatct gggttttcac gttcttcagg tgtcatcgaa gacacaatgg cacgtttacg
     2101 agcaatctgg cgttcatcca ccttcatgtt ttgaagtgct ggattgttgg ccatacctgg
     2161 aatcatcttg agcaagtctt ccatcggccc catattttgc acctgatcta attgatcgat
     2221 gaaatcatta aaatcaaagg tgttttcgcg catcttctca gccatttcaa gggctttttg
     2281 ttcatcgtat tcctgagaag ctttctcaat caaagtgagc atatccccca taccaaggat
     2341 acggctagac atgcggtctg ggtggaaggt ttcaatgtcc gtaatctttt cacctgtacc
     2401 agtgaacttg attggttttc cagtaatgtg acgaacagac agagcagcac caccacgagt
     2461 atcgccatca atcttggtaa ggatgacccc agtcacttcc aactgagcat taaactcacg
     2521 cgcaacattg gctgcttcct gaccaatcat agcatcaacg acaagcaaga tttcatttgg
     2581 ttgagccaat gctttcacat cacgaagctc attcatgagg agctcatcaa tctgcaaacg
     2641 acccgcagta tcaatcaaga catagtcgtt atgattagtt tgggcttgct ccaaaccttg
     2701 acgtacaatc tcaacagctg gtacttctgt tccaagtgca aagacaggca catcaatctg
     2761 ttgtcccaag gtcttaagct ggtcaatggc agctggacga taaatatccg ccgcaatcat
     2821 caaaggacga gcattttctt ctttcttgag tttgttggcc aatttaccag caaaggttgt
     2881 tttaccagcc ccttgtaaac caaccatcat gatgatggtt ggaatcttag gtgacttgat
     2941 aatttctgcc gtatcagaac ctaaaacggc tgtcagttcc tcatcaacga ttttaataat
     3001 ctgttgcgca ggattaagtg tatcaatgac ctcatgcccg actgcacgct cacgaacttt
     3061 cttgataaag tcctttacaa caggcaaggc aacgtcggcc tcgagcaagg ccaagcgaat
     3121 ttctttggtt gcctcttgga catcagattc agagattttt ccttttttac gtagattttt
     3181 aaagacgttc tgcaaacgtt ctgttaaact ttcaaatgcc atttttcttc ctcttattct
     3241 ctattatcaa tgcttgttaa aatttctatc tgctcctgca gaaagttatc cttgggatag
     3301 cgctccaaaa tctgatcaaa aatctgactg cggacaatat aatccgagta catgtgcaat
     3361 ttcatctcat aatcttccag aatcttttct gttcgcttga tattgtcata gacagcctga
     3421 cgactgacac cgaactcctc ggcaatttca gcaaggctgt aatcatcagc gtagtagagc
     3481 tcgatataat tcatttgctt atctgtcaaa agcgccgcat aaaattcaaa gagcgcattc
     3541 atacgattgg ttttttcgat ttccataact tttattatac caaaaattag cctaatctac
     3601 cacactagga agccgatcca agaagataga tagctaaatt tgaaaaagac atgagcctag
     3661 ccccaagtaa tttccaattg atagctggca aaaggatgtc cctcttgatt ttgtagttga
     3721 taatctagtt caatcttttg cctatcaact tgataatggc tcgtttggat gataaactcc
     3781 tgcatgccca taggtgtagg aatataggct aaactatcgc tatcctttag aaagcgcata
     3841 atggtcttgg gattagaaaa tcggctcatc ataagttctt gaccatgaaa tttaatcact
     3901 actttttcct tttcctcatt atagaaaagc aggtagctat aatctccttt ttcatgcact
     3961 tccacatcat aaagctggtc aatcacttcc aactgctcat caaactgaat tgtatttcgc
     4021 atccgaatct tcacatcagg ccctctttct tgtctcttgt cctactattt taccaaaaag
     4081 agcaggattt tgctataatg gtcatatgaa cgaaaaagta ttccgtgacc ctgttcacaa
     4141 ctacatccat gtcaataatc aaatcatcta tgacttgatt aatacaaaag aatttcagcg
     4201 tttgcgccgg atcaaacaac tgggaacttc cagttatacc ttccacggtg gagaacacag
     4261 tcgcttctct cactgtctag gagtctatga aattgcacga cgcatcacag agattttcga
     4321 agaaaaatat cctgaggaat ggaatcctgc cgagtctctc ttgaccatga ccgctgctct
     4381 cctacacgac cttgggcatg gtgcctactc ccatactttt gaaaatctct ttgatacaga
     4441 ccatgaagcc attactcagg agattattca aaatcctgag acagagattc accaagtcct
     4501 gctacaagtg gcacctgatt tcccagaaaa ggtggccagt gtcattgacc atacctatcc
     4561 taacaagcag gtcgtgcagc tcatttctag tcagattgac gcagatcgca tggactatct
     4621 cttgcgcgac tcctatttta caggagcatc ctatggggaa tttgacctga ctcgaatcct
     4681 ccgagtcatt cgtcctatcg aaaatggtat cgcctttcag cgcaatggca tgcacgccat
     4741 cgaagactac gtcctcagtc gctaccagat gtacatgcag gtttatttcc accccgcaac
     4801 acgcgccatg gaagttctcc tacagaatct tctcaaacgc gccaaggaac tctatcctga
     4861 ggacaaggat ttctttgccc gaacttctcc acacctcctg cctttcttcg aaaaaaatgt
     4921 gaccttgact gactatctgg ctctggatga tggtgtgatg aatacctact tccaactctg
     4981 gatgaccagt cctgacaaga ttcttgcaga tttatcgcat cgctttgtca accgcaaggt
     5041 ctttaaatcc attacctttt cacaagaaga ccaagaccaa ctcgctagca tgagaaaatt
     5101 ggt
//
LOCUS       DAVHTH010000089         5010 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.089, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000089 DAVHTH010000000
VERSION     DAVHTH010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5010)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5010)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5010
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.089"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            complement(<1..1853)
                     /locus_tag="VVR63_001976"
     CDS             complement(<1..1853)
                     /locus_tag="VVR63_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec-dependent serine-rich glycoprotein
                     adhesin"
                     /protein_id="HEU6129943.1"
                     /translation="MFKVMRGGVDTTQVMTETVEDKVSHSITGLDILKGIVAAGTVIS
                     GTVATQTKVFTNESAVLEKTVEKTDALATNDTVVLGTISTSNSASSTSLSASESASTS
                     ASESASTSASTSASTSASESASTSASTSISASSTVVGSQTAAATEATAKKVEEDRKKP
                     ASDYVASVTNVNLQSYAKRRKRSVDSIEQLLASINAAVFSGNTIVNGAPAINASLNIA
                     KSETKIYTGTGRDSFYNIPIYYKLTVTNDGSKLTFTYTVTYVDPITKTLGNLSRMSRG
                     YSIYNTGTIYQTMLTLGKGLKTPSSVKNYITDKDGVQVQYYNMSTMTTQGSGYTWGNG
                     AQMNGLFAKRGYGLTSSWTVPITGTDTSFTFTPYAAKTDKIRTNYFNSKGKIVESSTT
                     SQSLSQSKSLSVSASQSASASESASTSASASASTSASTSASTSASTSASTSASTSAST
                     SASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASASASTSASASA
                     STSASASASTSASASASTSASSSASTSASASASTSASASASTSASSSASTSASASAST
                     SASASASTSASESASTSASVSASTSASASASTSASASASTSASESASTSASA"
     gene            complement(1851..1964)
                     /locus_tag="VVR63_001977"
                     /pseudo
     CDS             complement(1851..1964)
                     /locus_tag="VVR63_001977"
                     /inference="COORDINATES: protein motif:HMM:TIGR03715.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="KxYKxGKxW signal peptide domain-containing
                     protein"
     gene            complement(2183..2662)
                     /locus_tag="VVR63_001978"
     CDS             complement(2183..2662)
                     /locus_tag="VVR63_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000514203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU6129944.1"
                     /translation="MGKERREQRNLERKKRVVKKRKIPLEELKAFVEAHPDAFLREIA
                     ARFDCALPSVWAVLKQIKVILKKTASFREQKPEKVSEFLDILDNLKDLPVLYIDETGI
                     NRYLYRPYAGAPRGEKVYDKISGRRFERTNEVEQKLNGSFLIRYIDSQIRERQNNYA"
     gene            complement(2629..2772)
                     /locus_tag="VVR63_001979"
     CDS             complement(2629..2772)
                     /locus_tag="VVR63_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tnpB"
                     /protein_id="HEU6129945.1"
                     /translation="MAYSTDFKQRALDSIKEGHRHVEAAKVFDVGARTLFTWEKKDVN
                     KGT"
     gene            3041..3421
                     /locus_tag="VVR63_001980"
     CDS             3041..3421
                     /locus_tag="VVR63_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEU6129946.1"
                     /translation="MTYLEKWFDFNRRQKEIESLLEETIAQQSEQSLTLKEFYLLYYL
                     DLAEEKSLRQIDLPDKLHLSPSAVSRMVARLEAKNCGLLSRMCCHQDRRSSFICLTND
                     GQKTLASLQKTVEESLEAGLDFLI"
     gene            3520..3741
                     /locus_tag="VVR63_001981"
     CDS             3520..3741
                     /locus_tag="VVR63_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HEU6129947.1"
                     /translation="MIEITYIDASKNERTVTFESYEDFERSQQACLIGVADYYPVQKL
                     TYKGHNLDYHGTYGDIFFYLMKQDLSQYN"
     gene            3758..4072
                     /gene="trxA"
                     /locus_tag="VVR63_001982"
     CDS             3758..4072
                     /gene="trxA"
                     /locus_tag="VVR63_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003004519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEU6129948.1"
                     /translation="MAKAITDATFEQETKDGLVLVDFWATWCGPCRMQGPILDKLSEE
                     LSEDVLKIVKMDVDENPNTARAFGIMSIPTLLFKKDGQVVKQVAGVHTAEQIKAIIAE
                     LS"
     gene            4379..4912
                     /gene="queF"
                     /locus_tag="VVR63_001983"
     CDS             4379..4912
                     /gene="queF"
                     /locus_tag="VVR63_001983"
                     /EC_number="1.7.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent 7-cyano-7-deazaguanine reductase
                     QueF"
                     /protein_id="HEU6129949.1"
                     /translation="MKRQSALVVFSGGQDSKTCLFWTMQHYETVEAVTFAYGQRHHLE
                     IQITREIAKEQGIRHHILDMSLLGQITAQPDFATIHISYIPDKLCVESKSLKLYLFSY
                     RNHGDFHENCINTIGKDLVNLLDPRYLEVWGKFTPRGGISIDPYYNYGKQGTKYEGLA
                     EQRLFQHDLYPEKIDNR"
BASE COUNT         1449 a         1052 c         1009 g         1500 t
ORIGIN      
        1 gctgacgcac tggtacttgc tgactctgat gcactggttg acgctgaagc cgaagcactc
       61 gttgatgctg aagctgatgc actagtactt gctgagactg acgcactcgt tgatgccgat
      121 tcagacgctg aggtacttgc tgaagccgaa gcactcgttg atgctgaagc tgaagcactg
      181 gtacttgctg aggatgacgc actggtactt gctgaagctg aggcgctagt acttgctgaa
      241 gccgaggcgc tggtgcttgc tgaggatgac gcactcgttg aggccgaagc tgacgcactc
      301 gttgatgctg aagccgaggc actggttgac gctgaagctg aggcgctagt acttgctgaa
      361 gccgaagcac tcgttgatgc cgatgtactt gctgacgtac ttgcgcttgt tgatgcggac
      421 gtgcttgctg acgtacttgc gcttgttgat gcggacgtac ttgctgacgt acttgcgctt
      481 gttgatgcgg acgtgcttgc tgacgtactt gcgcttgttg atgcggacgt acttgctgag
      541 gtcgacgcgc ttgttgacgc cgatgtactt gctgacgtgc ttgctgaagc cgacgcactc
      601 gttgatgccg attcagacgc tgaggcgctt tgactagcac ttactgagag tgacttagac
      661 tgtgaaagtg actgactggt cgtgctagat tcaactatct ttcctttact attgaagtag
      721 ttagttctaa ttttatctgt tttagcagcg taaggggtaa atgtaaagga tgtatccgtt
      781 ccagtaattg gtacagtcca agatgatgtt aatccatatc ctcgcttagc aaataaacca
      841 ttcatttggg caccatttcc ccaagtatac ccactaccct gcgtcgtcat tgtagacata
      901 ttatagtatt gaacctgtac accatctttg tcagtaatgt agttctttac acttgaaggt
      961 gttttcaatc cctttcctaa cgttaacatc gtttgataaa ttgttcctgt attatagata
     1021 gaatatccac gagacattct tgaaagattt ccaagagtct ttgtgatagg atctacatac
     1081 gtaaccgtat aggtaaaggt caattttgaa ccatcatttg tcactgtcaa tttatagtaa
     1141 attggaatat tataaaatga atctctacct gtacccgtgt aaatttttgt ctcactttta
     1201 gcaatgttta gacttgcatt aattgcaggg gcgccattta caatcgtatt gccagaaaaa
     1261 acagcagcat ttatagaagc cagcaattgc tcgatggaat ctactgaacg cttgcgtcgc
     1321 ttagcataag attggagatt gacatttgta actgatgcta cataatcact agctggtttc
     1381 ttacgatctt cttcgacctt cttagcagtt gcttctgtag cggcagctgt ttgtgaacct
     1441 accacagtag atgatgcaga aatacttgtc gaagccgatg tacttgctga ttctgatgca
     1501 cttgtactcg ctgaggtcga agcgctggtt gaggctgact cagatgcaga tgtacttgcc
     1561 gactctgaag ctgacaaact agttgaactc gctgaattac ttgtagatat cgtacctaga
     1621 actactgtat catttgttgc caaagcatcc gttttctcta cagttttttc aagtactgcc
     1681 gactcatttg taaatacctt cgtttgagtt gcaacggttc cacttatgac agttcccgca
     1741 gcaactatcc ccttgaggat atcaagccca gtaattgaat gacttacttt atcttctacc
     1801 gtttcggtca tgacctgagt agtatcaaca ccaccacgca tgaccttaaa caagccaaaa
     1861 agagaagtcg aggcccgtag ccaatgcttc cctgatttga ttaatttgaa ccgagttact
     1921 cggtctgttt ctctatattc acccttctga cgtctaaaaa atattttgaa atttcctttc
     1981 gagtattatt ttcatgtatg gatataaata aattaccata ctataattat agaataggga
     2041 acccaaaata gcaagaaact tgaggtattt ttgctaaaaa aaaaaagcat tttgctatct
     2101 tatatatata tataagataa gttttttata aatacacgca aatgagtata aatcggctaa
     2161 tttttggttt atattcctgt ttttatgcat aattattctg tcgttctcta atttgtgaat
     2221 caatatatct gattagaaaa ctaccattga gtttttgctc cacctcatta gtccgctcaa
     2281 aacgccgtcc gctaatcttg tcatagactt tctcccctct aggagcccct gcataaggac
     2341 gatagaggta gcggttgatt cccgtttcgt caatatatag gactggtaaa tcttttaggt
     2401 tatccaaaat atcaagaaac tcagaaactt tctcaggctt ttgttcccta aaactggccg
     2461 tcttttttaa aatgacctta atctgcttta aaactgccca tacggagggc aaagcacaat
     2521 caaaacgggc cgcaatttcc cgtaaaaaag cgtctggatg agcctctaca aaggctttca
     2581 attcttctaa agggatctta cgctttttga cgactcgctt tttccgctct aagttccttt
     2641 gttcacgtct ttcttttccc acgtgaagag agttctggcg ccaacatcaa aaactttggc
     2701 cgcctcgaca tgtctgtgcc cctctttgat ggaatctaat gctcgctgtt taaaatcagt
     2761 actatatgcc atagctttat tagaccatgc ttattttaaa ctaagcaact atagatagag
     2821 aaatgaaata aaatctgaat tcgaatgtga taaggagtta gaaattgaaa caataggatt
     2881 tccccattat tcacacaaaa ataaaaccac taaaaaacag agcttgccag cattcttgaa
     2941 aagtagtata attattgcat gcgcaatcat cttgtgacgc agagactgcc cgttaatgga
     3001 ctttcttcta ttttatgact ctaaaaagaa aggagacact atgacctatt tggaaaaatg
     3061 gtttgacttc aatcggcgtc agaaagaaat tgaaagtctc ttggaagaga ccattgccca
     3121 acagagcgag caaagtctga ccttgaaaga gttctacctg ctctactatc tggacttggc
     3181 tgaagaaaaa tctctacgcc agattgacct gccagataag cttcatctga gcccgagcgc
     3241 agtttctagg atggtggctc gcttggaagc taaaaattgc ggtttactca gtcgcatgtg
     3301 ttgccatcaa gatagacgct ctagttttat ctgcctgaca aatgatgggc aaaagacact
     3361 ggcctcgcta caaaagactg tcgaagaaag cttggaagca ggtttggatt tcttgattta
     3421 agatgatttt aaaaaaagtt gcgtgcgcaa tcatttttct tgacattctc ttttataagg
     3481 agtaaaataa agttagcatt aaacaaagga gttttaaaca tgattgaaat tacctatata
     3541 gatgccagca agaacgaaag aactgtgact ttcgagtctt atgaagactt tgaacgttcg
     3601 caacaagctt gccttatcgg cgtcgcagac tactaccctg tccaaaaatt aacttacaag
     3661 ggtcataatt tggactacca tgggacttat ggagatatct tcttctatct catgaaacaa
     3721 gatttaagcc aatataacta aaaaaaggag aaatacaatg gcaaaagcaa ttacagatgc
     3781 aacattcgaa caagaaacaa aagacggttt ggtcttagta gacttctggg caacttggtg
     3841 tggtccatgt cgtatgcaag gtccaatctt ggacaaattg tctgaagaac tttcagaaga
     3901 tgtcttgaaa atcgttaaaa tggacgttga tgaaaatcca aacacagctc gtgcttttgg
     3961 aatcatgtct attccaactc ttctcttcaa aaaagacggc caagttgtca aacaagttgc
     4021 aggtgttcac acagcagaac aaatcaaggc catcattgct gaattgagct aatcaaacga
     4081 gagaccaagt actttctttg gtctcttttt tcttgccctt tgccattttt caaaaaatat
     4141 gctagactat agtagattga aactagaata gtacatctct acttctaaaa cattgttaga
     4201 aatcgatttg actgtcctga tcgatttgtc ctgttcttat ttcattttac tatataaata
     4261 gaatattacg atatttggga tatgccatcg ctaaaaaaaa cctcgatttg gtatttttta
     4321 gctccctaat gggagctttt tacgtgctct gaacatttcc cattttggaa ggagtactat
     4381 gaaacgtcaa tcagccttgg tcgtctttag tggtggtcaa gattcaaaaa cctgcctttt
     4441 ctggaccatg caacactatg aaacagtcga agctgtcacc tttgcctacg gccaacgtca
     4501 tcacctcgaa attcaaatca ctagagaaat cgctaaggaa cagggcattc gtcaccatat
     4561 cctcgatatg tctctgctgg gacaaatcac tgctcagcca gactttgcga cgattcatat
     4621 ttcctacatt cctgacaagc tctgtgtcga gtcaaaatcc ctcaaactat atctatttag
     4681 ctaccgaaac cacggagatt tccacgaaaa ctgtatcaac accatcggga aagacttggt
     4741 caacttgcta gaccctcgct atttagaagt ctggggaaaa ttcactccgc gcggtggcat
     4801 ttcaatcgac ccctactata actacggtaa gcaaggaact aagtatgagg gcttggcaga
     4861 acaacgcctc ttccaacacg acctttatcc agagaaaatt gacaaccgct aaagtcatac
     4921 tcaatgaaaa tcaaagagca aactaggaag ttagccgcag gttactcaaa gcagtgtttg
     4981 aggttgtaga taaaactgac gaagtcagct
//
LOCUS       DAVHTH010000090         4986 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.090, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000090 DAVHTH010000000
VERSION     DAVHTH010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4986)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4986)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4986
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.090"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            <1..278
                     /locus_tag="VVR63_001984"
     CDS             <1..278
                     /locus_tag="VVR63_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="phosphohydrolase"
                     /protein_id="HEU6129950.1"
                     /translation="TAIHKNFDLPYDIYRPESENPRTQIEILQKNGELAELSSLSPIV
                     QSLAGSRHGDNRFYFPKEMLDQNSIFASITQQFLHLIENDHFTPNKN"
     gene            291..1097
                     /gene="yidA"
                     /locus_tag="VVR63_001985"
     CDS             291..1097
                     /gene="yidA"
                     /locus_tag="VVR63_001985"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000023490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HEU6129951.1"
                     /translation="MSIKLIAVDIDGTLVNSQKEITPEVFSAIQDAKEAGVKVVIATG
                     RPIAGVAKLLDDLQLRDQGDYVVTFNGALVQETATGHEIISESLTYEDYLDMEFLSRK
                     LGVHMHAITKDGIYTANRNIGKYTVHESTLVSMPIFYRTPEEMAGKEIVKCMFIDEPE
                     ILDAAIEKIPAEFYEHYSINKSAPFYLELLKKNVDKGSAITHLAEKLGLTKDETMAIG
                     DEENDRAMLEVVGNPVVMENGNPEIKKIAKYITKTNDESGVAHAIRTWVL"
     gene            complement(1152..1223)
                     /locus_tag="VVR63_001986"
     tRNA            complement(1152..1223)
                     /locus_tag="VVR63_001986"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1188..1190),aa:Arg,seq:cct)
     gene            complement(1265..1612)
                     /gene="rplS"
                     /locus_tag="VVR63_001987"
     CDS             complement(1265..1612)
                     /gene="rplS"
                     /locus_tag="VVR63_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HEU6129952.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGNRERIQIFE
                     GVVIARKGAGISENYTVRKISNGVGVERIFPIHTPRVEKIEVVRYGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            complement(1731..2060)
                     /gene="crcB"
                     /locus_tag="VVR63_001988"
     CDS             complement(1731..2060)
                     /gene="crcB"
                     /locus_tag="VVR63_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HEU6129953.1"
                     /translation="MVIVYLAIACGLGALVRYFFSRYNQASKLPLGTLIANLLGCFLI
                     GVFYNHVESKEVYAILATGFCGGLTTFSTLNDELQRLLSDKKVFYSYLTLTYIGGLVA
                     IFLGILL"
     gene            complement(2054..2428)
                     /gene="crcB"
                     /locus_tag="VVR63_001989"
     CDS             complement(2054..2428)
                     /gene="crcB"
                     /locus_tag="VVR63_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HEU6129954.1"
                     /translation="MKKEQFYPLGIFLAAMLGGLVRYLVSTWLPASPDFPWGTLFVNY
                     LGIFCLIYLVKGYLVYKGTSKGLILALGTGFCGGLTTFSSLMLDTVKLLDTGRYLSLI
                     LYLLLSIGGGLLLAYYLGRKKW"
     gene            complement(2425..2691)
                     /locus_tag="VVR63_001990"
     CDS             complement(2425..2691)
                     /locus_tag="VVR63_001990"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HEU6129955.1"
                     /translation="MDLDIIRQEIDQIDDQIVKLLEERMHLVEGVVAYKKASGKPILD
                     TKREAVIFEKVRSRVEDKRYQETIVATFSDILKRSRDYQDQNIK"
     gene            complement(2807..3250)
                     /locus_tag="VVR63_001991"
     CDS             complement(2807..3250)
                     /locus_tag="VVR63_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HEU6129956.1"
                     /translation="MALAKIVFASMTGNTEEIADIVADKLRDLGLDVDVDECTTVDAS
                     DFLEADIAIVATYTYGDGELPDEMMDFYEDLADLNLNGKIYGVVGSGDTFYDEFCKAV
                     DDFDRVFVSTGAEKGSECVKVDLSAEEEDIERLEQFAEELAAKVG"
     gene            3354..4289
                     /locus_tag="VVR63_001992"
     CDS             3354..4289
                     /locus_tag="VVR63_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HEU6129957.1"
                     /translation="MEICQQILEKIKEYDTIIIHRHMKPDPDALGSQVGLKALLEHHF
                     PEKTIKAVGFDEPTLTWMAEMDLVEDRAYQGALVIVCDTANTARIDDKRYSQGDFLIK
                     IDHHPNDDVYGDLSWVDTSSSSASEMITLFAQTTQLALADRDAELLFAGIVGDTGRFL
                     YPSTTARTLRLAAYLREHNFDFAALTRKMDTMSYKIAKLQGYIYDHLEVDENGAARVI
                     LSQKILKQYNITDAETAAIVGAPGRIDRVSLWGIFVEQADGHYRVRLRSKVHPINEIA
                     KEHDGGGHPLASGANSYSLEENEIIYQKLKNLLKN"
     gene            4343..4627
                     /locus_tag="VVR63_001993"
     CDS             4343..4627
                     /locus_tag="VVR63_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HEU6129958.1"
                     /translation="MARKETMAERKYCKMKKDIHPEYRPVVFMDTTTGYQFLSGSTKR
                     SNETVEFEGETYPLIRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLK"
     gene            complement(4684..4902)
                     /locus_tag="VVR63_001994"
     CDS             complement(4684..4902)
                     /locus_tag="VVR63_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6129959.1"
                     /translation="MSISPRFETLEQAIASKDLEKVREAFKKMNSTWTINESVVRDNS
                     IAHYGRVETAISFLPSSMEIEPTDESGT"
BASE COUNT         1568 a         1132 c          922 g         1364 t
ORIGIN      
        1 atactgccat tcataagaac tttgacctcc cttatgatat ttaccgtccc gaatctgaaa
       61 atccaaggac acagattgag attttacaaa aaaatggaga actggcagaa ctctctagcc
      121 tgtcccctat cgtccaatcc cttgctggaa gtcgccacgg agataatcgc ttttatttcc
      181 cgaaagaaat gttagaccaa aacagcatct tcgcaagcat cacccagcaa tttttacact
      241 tgattgagaa cgatcatttt accccaaata aaaactaaaa gaggaaattt atgagtatta
      301 aactaatcgc cgtcgatatt gacggaaccc tagtcaacag ccaaaaagaa atcactcctg
      361 aagtcttttc tgccatccaa gatgccaaag aagctggtgt caaagtcgtg attgcaactg
      421 gccgccccat cgcaggtgtt gccaaacttc tggacgactt gcagttgaga gaccaaggtg
      481 actatgtggt gaccttcaat ggtgcccttg tccaagaaac tgctactggc catgagatta
      541 tcagcgaatc cttgacctat gaggattatc tggatatgga attcctcagt cgcaagctcg
      601 gtgtccacat gcatgccatt accaaggacg gtatctatac tgcaaatcgc aatatcggaa
      661 aatacactgt acacgaatca accctcgtca gcatgcctat cttctaccgt acccctgaag
      721 aaatggctgg caaggaaatt gtcaagtgta tgttcatcga tgaaccagaa atcctcgatg
      781 ctgcgattga aaaaatacca gccgaatttt acgagcacta ctctatcaac aaatctgctc
      841 ctttctacct cgaactcctt aaaaagaatg tagacaaggg ttcagctatt actcacttag
      901 ctgaaaaact aggattaacc aaagatgaaa ccatggctat cggagacgaa gaaaatgacc
      961 gtgccatgct ggaagtcgtt ggcaatcctg tagtcatgga aaacggaaat ccagaaatca
     1021 aaaaaatcgc caaatacatc accaaaacaa atgacgaatc cggcgttgcc catgctattc
     1081 gtacatgggt actgtaaaag gaaagaatag ataaaaaccg ctcagctgag cggtttttga
     1141 tatctaatta ctgccccctg caggaatcga acctgcaact actccttagg agggagttgt
     1201 tatatccatt gaactaaggg agctagataa aaactctgct gaaaagcaga gttttttagt
     1261 cgaattaacg acggatttct ttgatacgag ctgccttacc ttgaagagca cgcaagtagt
     1321 acaatttcgc acgacgtact ttaccgtaac gaacaacttc gattttttca acacgtggag
     1381 tgtggattgg gaagatacgc tcaacaccta caccgttaga gattttacga actgtgtagt
     1441 tttctgagat tccagcacct ttacgtgcga taacaacacc ttcaaaaatc tggatacgtt
     1501 cacggttacc ttcgacaact ttcgcatgta cacgaacagt gtcaccagga cggaatgatg
     1561 ggatatctgt acgaagttga ccttcagtca agctttggat taatggattc attttattct
     1621 cctatctttg tcaatcttga ggaatcttcc tcagcggata aactgtattt ttgtgcgtcc
     1681 attacacaca agatatagtt taccaaattt ctaaaaaaaa gtaaagaaat ttatagcaaa
     1741 attcctaaaa aaatcgcaac caaaccacct atgtaagtca aagtcaggta agaataaaag
     1801 accttcttat cacttagcag tctttgaagt tcgtcattca aggtcgaaaa agttgttaaa
     1861 ccgccacaaa atcctgttgc tagaatagca tatacttcct tagactctac atgattgtag
     1921 aatactccaa ttaaaaaaca acctaaaaga ttagctatga gcgttccgag tggcaattta
     1981 gaagcttgat tatagcgaga aaagaaatac cgtacgagtg ctcccaagcc acaggcgatt
     2041 gcaagataga cgattaccat ttcttcctcc ccaaatagta agctaaaagc aggcctccac
     2101 cgatactcaa aagcaaatac agtatcaaac taagataacg ccctgtatca agcagcttca
     2161 cagtatcaag cattaggctg gaaaaagttg ttaaacctcc gcaaaaaccc gtccccagtg
     2221 ctaaaatcaa gcccttacta gtccccttat agaccagata gcccttgaca agataaatca
     2281 agcagaaaat tcccagatag ttgacaaaga gagtgcccca agggaaatct ggactggctg
     2341 gtaaccaagt ggaaactagg tagcggacaa gtccgcccaa catagcagct agaaaaatcc
     2401 ctagcggata aaattgttct tttttcattt gatattttga tcctgataat cacgcgaacg
     2461 tttgagtatg tccgaaaaag tcgcgacaat agtctcctga tagcgcttgt cctctacacg
     2521 acttctaacc ttttcaaaaa taactgcttc tctcttagta tctaaaatcg gtttccctga
     2581 agccttctta taagcgacaa ctccttcaac taagtgcatt cgttcttcta acagtttgac
     2641 aatttggtcg tcgatttgat cgatttcttg acgaataata tctaaatcca tacagtctcc
     2701 tcctttattt gaattattgt atcaaaaagc catcaattag gctagtaaaa tcccaactct
     2761 cgataagaaa aatgcactga ttgattacat cagcgcactt ttatgcttat cctactttag
     2821 cagccaattc ttctgcgaat tgttccaagc gttcaatatc ttcttcctcg gcagaaagat
     2881 caactttaac acactctgaa cctttttctg ctcctgttga cacaaagaca cggtcaaagt
     2941 catcaacagc cttacaaaat tcatcgtaga aggtatctcc tgagccgacc actccgtaga
     3001 ttttgccatt caagttgaga tctgctaggt cttcgtagaa gtccatcatc tcatctggca
     3061 attcaccatc accataagta taggtcgcaa cgatagcgat gtctgcttcc aagaagtctg
     3121 aagcgtcaac agttgtacat tcatcaacat caacatccaa gcccaagtca cgtaatttgt
     3181 ctgctacaat atctgcaatt tcttcggtat taccggtcat actggcaaat acaatttttg
     3241 ctaatgccat atcgtcctcc tcaatttatc tttctccatt atatcacatc tttttcattt
     3301 taaaaataaa aattcttgtg ctacaatgaa atgagaaaga attgaggtta tttatggaga
     3361 tttgccaaca aattttagaa aaaattaaag aatacgacac cattatcatt catcgtcata
     3421 tgaaaccaga ccctgatgcc ttgggaagtc aggtgggatt gaaagccttg ctagaacatc
     3481 atttcccaga aaaaaccatc aaagccgtcg gttttgatga accaactctt acttggatgg
     3541 ctgagatgga tcttgttgaa gatagagcct accaaggcgc acttgtcatc gtctgtgata
     3601 cagctaatac tgctcgtatc gatgataagc gctatagtca aggtgatttt ctcattaaga
     3661 ttgaccacca tccaaatgat gatgtatacg gtgacctgtc ttgggtcgat actagttcaa
     3721 gtagcgctag cgagatgatt accctatttg cccaaacaac ccaactagcc ttggcagatc
     3781 gcgatgctga gttgctcttt gcaggaattg tcggtgatac aggtcgcttc ctctaccctt
     3841 ctaccactgc acggactctt cgcctggctg cttatttgag agaacataac tttgactttg
     3901 cggctctcac tcgcaaaatg gacactatga gctacaaaat tgctaaactg caaggctaca
     3961 tctacgacca tctggaagtg gatgaaaatg gtgctgctcg cgttatcctg agtcagaaaa
     4021 tcttgaaaca atacaatata accgatgctg aaactgcggc cattgtaggt gcacctggac
     4081 gcattgacag agtgagtctc tggggaattt ttgtcgaaca ggctgatggc cactaccgag
     4141 ttcgcttacg cagtaaagtc catcctatca atgaaattgc caaggagcat gatggtggag
     4201 gccaccctct agcaagtggt gctaattcct atagcctaga agaaaacgaa atcatctacc
     4261 aaaagttaaa aaacttgctt aaaaactgat aaaatacttg ccaaactttt cagaatctga
     4321 tagactagta tagtaacaat ctatggctcg caaagagacc atggcagaaa ggaaatattg
     4381 caaaatgaaa aaagatatcc atccagaata tcgcccagtt gtcttcatgg acacaactac
     4441 tggttaccaa ttccttagcg gttcaacaaa acgctctaac gaaacagttg agttcgaagg
     4501 cgaaacttac ccattgatcc gtgtggaaat ttcatcagac tcacacccat tctacactgg
     4561 acgtcaaaag ttcactcaag cagatggacg cgtggatcgt ttcaacaaaa aatacggtct
     4621 caaataatga taagagaaca gttttggctg ttcttttttg tttcttgaaa tcaactgctg
     4681 ttttcatgtt ccagactcat ctgtaggttc gatttccatg ctactaggca ggaaggaaat
     4741 agctgtttca acacgtccat aatgagctat actattgtca cgaaccacac tttcattgat
     4801 ggtccaagtg gaattcattt tcttaaaagc ttctcggact ttttccaaat ctttggaggc
     4861 aatggcctgc tctaaggttt caaaacgagg acttatactc atatgctttc aaaaagcatt
     4921 ctagtccatc tccgattacc gatggacttt atcacctcct tctccagtcc ttgtatgaca
     4981 tcttga
//
LOCUS       DAVHTH010000091         4789 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.091, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000091 DAVHTH010000000
VERSION     DAVHTH010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4789)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4789)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4789
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.091"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            188..376
                     /locus_tag="VVR63_001995"
     CDS             188..376
                     /locus_tag="VVR63_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0227 family bacteriocin-like peptide"
                     /protein_id="HEU6129960.1"
                     /translation="MELVLPNNYVVIDEEEMMYLDGGAYLSKRACQGICAALAMSSGT
                     FIALAGAAVLTKKTNKLY"
     gene            539..1267
                     /locus_tag="VVR63_001996"
     CDS             539..1267
                     /locus_tag="VVR63_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6129961.1"
                     /translation="MSNVDKIRKIHIIVCWMYIFLSFRAIINDTEYFLLIFLAFIYSI
                     VSLPLYSVKNKIVSICLVINSILLMSFPILINKFFPESFLTYIVLISVFITELIIFHL
                     IGKDFDTKLTNEYKKISQFRSKVSQSPWIKYLEISSFILTIFPSILYGTVDNHVLTLI
                     FLIKICVDTTIKFLFIRLFDTSTLMKRRIFFLFALDVIAYLFLGYLLVIQKAGYLFSV
                     LLLFSNFSVPFIKEKEYELFKNSK"
     gene            2402..2641
                     /locus_tag="VVR63_001997"
     CDS             2402..2641
                     /locus_tag="VVR63_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6129962.1"
                     /translation="MKLLDCILDYQERFNGKTCQVSTNYKYLEIFKVNFCLTDLHHLF
                     DLYKITRDYASQTKPAIQAGVFILEDFRNILCTMM"
     gene            3190..>4789
                     /gene="pspA"
                     /locus_tag="VVR63_001998"
     CDS             3190..>4789
                     /gene="pspA"
                     /locus_tag="VVR63_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal surface protein A"
                     /protein_id="HEU6129963.1"
                     /translation="MNKKKMILTSLASVAILGAGFVASSPTVVRAEDAPQVVEKSSLE
                     KKYEEAKTKADTAKKDYETAKKKAEDAQKKYDEDQKKTEEKAKKEKEAAKKVDDASLA
                     VQKAYVEYRKVQESRSNYRNRSDYNKKLAEAQVKIDEANKKLTAANNEFKTVRAVVVP
                     EPNALAETKKKAEEAKAEEVVAKKKSDKAAQEVEVAKKEVEAKELEIEKLQDEISTLE
                     QEVATAQHQVDNLKKLLAGVDPDDTEAIEAKLKKGEAELNAKQAELAKKQTGLEKLLD
                     SLDPEGKTQDELDKEAAEAELDKKADELQNKVADLEKEISNLEILLGGADPEDDTAAL
                     QNKLATTKAELEKTQKELDAALNELGPDGDEEETPAPAPQPEQPAPAPAPKPEQPAPA
                     PKPEKSADQQAEEDYARRSEEEYNRLTQQQPPKAEKPAPAPAPKPEQPAPAPKTGWKQ
                     ENGMWYFYNTDGSMATGWLQNNGSWYYLNSNGAMATGWAKVNGSWYYLNANGSMATGW
                     VKDGDTWYYLEASGAMKASQWFKVS"
BASE COUNT         1712 a          677 c          946 g         1454 t
ORIGIN      
        1 taaaatcagg gaatcagtga ttagctgtta tttgaattaa gtaaactgtt aagcttcaag
       61 cagtaactgg ttttaaatat ttaaaataag ataaagaaag gaagtctaat ttaggtaact
      121 aaacaaagcc tgcgatcact tgttaggaaa ccatcctaac catgcttaat aaaaaaggag
      181 aaaataaatg gaacttgtat taccaaataa ttatgttgtg attgatgaag aagagatgat
      241 gtaccttgat gggggagctt atttaagcaa gcgtgcttgt caaggaattt gcgcagcttt
      301 agctatgagt tcaggaactt ttatagcatt agctggagct gcagttttaa ccaaaaaaac
      361 taataaacta tattaaggtt ggaggtcttg gaggctggct tattggtgca gcagcaggtg
      421 tattggctac agcagcaggg aaaatagctt actgtattgg atatggtgtt cttaatagag
      481 gttgtgatat taacgggaac ccttatcctt gggatggatt catatctgcg acagtaagat
      541 gagtaatgta gataagattc gaaaaataca tattatcgtt tgttggatgt atatattttt
      601 atcattcagg gcgattataa atgacacgga gtattttttg cttatttttt tagcttttat
      661 ctactcaata gtatcactac ctctatattc tgtgaaaaat aaaatagtat ctatctgtct
      721 agttataaat tcgattctgt taatgagttt tcccatttta atcaataaat ttttcccaga
      781 aagttttttg acttatatcg tattaataag tgtttttatt acagagttga taatttttca
      841 tttaattggg aaagattttg atactaaatt gactaacgaa tataagaaaa ttagtcagtt
      901 tagaagcaag gtgtctcaat ctccttggat aaaatattta gagatttcta gttttatatt
      961 aactatattt ccatctattc tttatggtac agttgataat catgtactga ctcttatctt
     1021 tttgataaaa atttgtgtag atactacgat aaaattttta ttcatcagat tatttgacac
     1081 aagtacttta atgaagagga gaatattttt tcttttcgca ttggatgtta tagcttactt
     1141 atttttagga tatcttttag tgattcaaaa agcaggctat ttgttttcgg ttttacttct
     1201 tttttctaat ttttcagttc catttatcaa agaaaaggaa tacgaattat ttaaaaatag
     1261 caagtaatag aaacataggt taaatcttag aacggcttaa aatcagatat gataaaggga
     1321 aatagtctta tctaggtaac taagtgctac aaacacagtc gaggatcact tgttaggatt
     1381 acattttaat catgcttaat aagaatggag aattcctatg gggattgtat tactctgaac
     1441 tttcgaatac cttagttctc gtgattttga gctattctag gtttagaatc cttcagaatg
     1501 taaaatttta agcagtcaaa gacttagaat agcctgaaaa catttatttt atagcaattc
     1561 taaacttaga attgctcata tatatgtatt tgagctgctc gatagttagg acagctctat
     1621 tctgagaaat ctgagctatc aatgcttcag aatagtattt cgccaatggt ttttattgaa
     1681 gaggtgattg ttttatgata gtctaaaata aaactgattt aatggagtaa atggagaatc
     1741 gttacatgaa acattttttt gcaggaattg gtgagataaa acttgttggc tacttattgt
     1801 atatatgtgt aggactagcc cctctttttc atatatatat gtcataggtt cggaactgag
     1861 ttttgtgaaa atagtgttat ctattttggg agttatattt gtaagtatgt taactattgc
     1921 tcgaatttat cggacttttc tataaagaat agtttggact tgaactgtat ctaaaaacag
     1981 aggttggtcg attatcagcc tctttcttgt cgttgaaaag agtgagatat attgactttt
     2041 gaaaaaaatg tcataattga gttgggataa acctaaaagt aatatagtag attgaatctg
     2101 gaatagtccg ttatgactgt taaaatattt ctagaaatta atttgacttt cctaatcgat
     2161 ttgttcacat cttgtttcaa tctactatac tttctcgtta aaccgttcgg caattcatgg
     2221 tgacatggac acatagtagt aagcacacta tgtggcttgg cagagctaaa aactgttccc
     2281 ttgcgataag cctaataagc acaacatagg gagttagaga agccgactct aatcaaccac
     2341 tttgggcaat agtgagaact gccccgtgct tttttatttt gagaaaatat ggagtttgtc
     2401 gttgaaatta cttgattgta ttttggacta tcaagaaaga ttcaatggaa aaacatgtca
     2461 agtatcaacg aattataagt atttagagat tttcaaagtg aatttttgtt tgactgattt
     2521 acatcattta tttgacttat acaaaatcac acgagattat gctagtcaaa caaaacctgc
     2581 tattcaagct ggtgttttta ttttagaaga ttttagaaat atcctatgta caatgatgta
     2641 atcgaaagga tatctttata tgagtttatc ggtgatattt tctattctaa aataataagt
     2701 tgttgcatcg tagctagcga tttatctaaa aatactatga aattggacgt catatttttt
     2761 gaggataaaa ataaaagatc cgcagtttta ggtttacgaa gagacaaaag cggagtattt
     2821 aaaccagtta ctctacattt tataagcgct aagaaatatg ttaaagttcg taaaacagat
     2881 gtgaaagaaa tgaaatggct ataaagattg tccgcaggct taagcttgcg ttttttgttg
     2941 tttaacgaaa ttaaaaaaca agctctctca tcggaagtgt ttttatagga atgaaggaag
     3001 atgatgctat gtttaaaaag agaatcgaaa agggcaaaag tagtgtcttt atctttttgg
     3061 agtagaagct tatgatatag aaatttgtaa taaaaatgta atataaaaca tttgacaaat
     3121 atttacgggg ggagtatact taatataagt atagtctaaa aatgactatc agaaaagagg
     3181 taaatttaga tgaataagaa aaaaatgatt ttaacaagtc tagccagcgt cgctatctta
     3241 ggggctggtt ttgttgcgtc ttcgcctact gttgtaagag cagaagacgc tccacaagtt
     3301 gtcgaaaaat cttcattaga gaagaaatat gaggaagcaa aaacaaaagc tgatactgcc
     3361 aagaaagatt acgaaacggc taaaaagaaa gcagaagacg ctcagaagaa atatgatgag
     3421 gatcagaaga aaactgaaga gaaagcgaaa aaagagaaag aagctgctaa gaaagtagac
     3481 gatgctagtt tagcggtaca aaaagcatat gtagaatata gaaaagttca agaatctcgt
     3541 agtaattaca gaaatcggag tgattataat aaaaaattag cagaggcgca agtaaaaata
     3601 gatgaagcga ataaaaaact aaccgcagct aataatgagt ttaaaactgt aagagcagtt
     3661 gtagttcctg aaccaaatgc gttggctgag actaagaaaa aagcagaaga agctaaagca
     3721 gaagaagtag tagctaagaa aaaatctgat aaggcagctc aagaggtaga agtagcgaag
     3781 aaagaagtag aggctaagga acttgaaatt gaaaaacttc aagatgaaat ttctactttg
     3841 gaacaagaag ttgctactgc tcaacatcaa gtagacaatt tgaaaaaact tcttgctggt
     3901 gtggatcctg atgatacaga agctatagaa gctaaattaa aaaaaggaga agctgagcta
     3961 aacgctaaac aagctgagtt agcaaaaaaa caaacaggac ttgaaaaact tcttgacagc
     4021 cttgatcctg aaggtaagac tcaggatgaa ttagataaag aagctgctga agctgagttg
     4081 gataaaaaag ctgatgaact tcaaaataaa gttgctgatt tagaaaaaga aattagtaac
     4141 cttgaaatat tacttggagg ggctgatcct gaagatgata ctgctgctct tcaaaataaa
     4201 ttagctacta caaaagctga attggaaaaa actcaaaaag aattagatgc agctcttaat
     4261 gagttaggcc ctgatggaga tgaagaagaa actccagcgc cggctcctca accagagcaa
     4321 ccagctccag ctcctgcacc aaaaccagag caaccagctc cagcaccaaa accagagaag
     4381 tcagcagatc aacaagctga agaagactat gctcgtagat cagaagaaga atataaccgc
     4441 ttgactcaac agcaaccgcc aaaagcagaa aaaccagctc cagctcctgc accaaaacca
     4501 gagcaaccag ctcccgcacc aaaaacgggc tggaaacaag aaaacggtat gtggtacttc
     4561 tacaatactg atggttcaat ggctacaggt tggctacaaa acaacggttc atggtactac
     4621 ctcaacagca atggcgctat ggcgacaggt tgggctaaag tcaacggttc atggtactac
     4681 ctcaacgcta acggttcaat ggcaacaggt tgggtgaaag atggagatac ctggtactat
     4741 cttgaagcat caggtgctat gaaagcaagc caatggttca aagtatcag
//
LOCUS       DAVHTH010000092         4499 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.092, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000092 DAVHTH010000000
VERSION     DAVHTH010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4499)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4499)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4499
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.092"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            complement(54..1040)
                     /locus_tag="VVR63_001999"
     CDS             complement(54..1040)
                     /locus_tag="VVR63_001999"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019768616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HEU6129964.1"
                     /translation="MTSTKQHKKVILVGDGAVGSSYAFALVNQGIAQELGIIEIPQLH
                     EKAVGDALDLSHALAFTSPKKIYAAQYSDCADADLVVITAGAPQKPGETRLDLVGKNL
                     AINKSIVTQVVESGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQ
                     ALAEKLDVDARSVHAYIMGEHGDSEFAVWSHANIAGVNLEEFLKDTQNVQEAELIELF
                     EGVRDAAYTIINKKGATYYGIAVALARITKAILDDENAVLPLSVFQEGQYGVENVFIG
                     QPAVVGAHGIVRPVNIPLNDAETQKMQASAKELQAIIDEAWKNPEFQEASKN"
     gene            1234..3702
                     /gene="gyrA"
                     /locus_tag="VVR63_002000"
     CDS             1234..3702
                     /gene="gyrA"
                     /locus_tag="VVR63_002000"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001152996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HEU6129965.1"
                     /translation="MQDKNLVNVNLTKEMKASFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRYMLVD
                     GHGNFGSMDGDSAAAQRYTEARMSKIALEMLRDINKNTVDFVDNYDANEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLGETIDAVKLVMDNPEVTTKDLMEVLPGPDFPTG
                     ALVMGKSGIHKAYETGKGSIVLRSRTEIETTKTGRERIVVTEFPYMVNKTKVHEHIVR
                     LVQEKRIEGITAVRDESNREGVRFVIEVKRDASANVILNNLFKMTQMQTNFGFNMLAI
                     QNGIPKILSLRQILDAYIEHQKEVVVRRTRFDKEKAEARAHILEGLLIALDHIDEVIR
                     IIRASETDAEAQAELMSKFKLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILAKPERVSQIIKDELDEVKRKFSDKRRTELMVGQILSLEDEDLIEESDVLITLS
                     NRGYIKRLDQDEFTAQKRGGRGVQGTGVKDDDFVRELVSTSTHDHLLFFTNKGRVYRL
                     KGYEIPEYGRTAKGLPVVNLLKLDEDESIQTVINVESDRSDDAYLFFTTRHGIVKRTS
                     VKEFANIRQNGLKALNLKDEDELINVLLTEGDMDIIIGTKFGYAVRFNQSAVRGMSRI
                     ATGVKGVNLREGDTVVGASLITDQDEVLIITEKGYGKRTVATEYPTKGRGGKGMQTAK
                     ITEKNGLLAGLMTVQGDEDLMIITDTGVMIRTNLANISQTGRATMGVKVMRLDQDAQI
                     VTFTTVAVAEKEEVGTENETEGEA"
     gene            3702..4445
                     /gene="srtA"
                     /locus_tag="VVR63_002001"
     CDS             3702..4445
                     /gene="srtA"
                     /locus_tag="VVR63_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtA"
                     /protein_id="HEU6129966.1"
                     /translation="MSQKNNKKKNKRKNLLTNILAGFLILLSLALIFNTQIRNIFIVW
                     NTNKYQVSQVSKEKLEENQDTEGNFDFDSVKAISSEAVLTSQWDAQKLPVIGGIAIPE
                     LEMNLPIFKGLDNVNLFYGAGTMKREQVMGEGNYSLASHHIFGVDNANKMLFSPLDNA
                     KNGMKIYLTDKNKVYTYEIREVKRVTPDRVDEVDDRDGVNEITLVTCEDLAATERIIV
                     KGDLKETKDYSQTSDEILTAFNQPYKQFY"
BASE COUNT         1371 a          794 c         1008 g         1326 t
ORIGIN      
        1 taatacagga aaaaacaact ccctgatgat tcaaggagtt gtctatagtt aaattagttt
       61 ttagaagctt cttggaattc tggatttttc catgcttcgt caataatagc ttgcaattct
      121 ttagcagatg cttgcatttt ttgagtttct gcatcgttca atggaatgtt tactggacga
      181 acgataccat gtgcaccaac aacagctggt tgaccgataa agacattctc aactccgtat
      241 tgaccttctt ggaatactga aagtggaagt actgcgtttt catcgtcaag gattgcttta
      301 gtgatacgag caagggctac tgcgataccg tagtatgttg cacctttttt gttgatgatt
      361 gtgtaggctg catcacgaac accttcgaac aattcaatca attcagcttc ttgaacattt
      421 tgagtatctt taaggaattc ttcaaggttt acaccagcga tgttagcgtg tgaccaaaca
      481 gcgaactcag agtcaccgtg ttcacccatg atgtaggcgt gaactgaacg agcatctacg
      541 tccaattttt cagcaagtgc ttgacggaaa cgagctgagt caagtgaagt acctgaaccg
      601 ataacgcgtt ctttagggaa accagagaat ttccaagttg agtaagtcaa aacgtcaact
      661 gggttagcag caacaaggaa gatacctttg aaacctgatt caacaacttg agttacgatt
      721 gatttgttga tagcaaggtt tttacctaca aggtcaagac gagtttcacc tggtttttga
      781 ggtgcacctg cagtgatcac aacaaggtca gcgtctgcac agtcagagta ttgagctgca
      841 tagatttttt taggtgaagt gaaggcaagg gcgtgactaa ggtcaagcgc atcaccaaca
      901 gctttttcat gcaattgtgg aatttcgata attccaagct cttgtgcaat tccttggtta
      961 acaagtgcaa aagcgtaaga tgaacctaca gcaccatcac cgacaaggat aacttttttg
     1021 tgttgtttag ttgaagtcat tgttttaaac atctccttaa ttttattagg ggattttccc
     1081 tagacaactt cattctatca cttttaaaaa actttgtcac gaatatgcct tatagttctc
     1141 gatgtaaacg ttttagtggt ttagaggctg aaatagatgg gaatttatgg tataatgttg
     1201 ttacttacta attgtgaaat gaggcattta ttaatgcagg ataaaaattt agtgaatgtc
     1261 aatctgacaa aggagatgaa ggcaagtttt atcgactacg ccatgagtgt tatcgtagcg
     1321 cgagctcttc ctgatgttcg agatggctta aaacctgttc accgtcgcat tctctacgga
     1381 atgaatgaat tgggtgtgac cccagacaaa ccccataaaa aatctgctcg tattacaggg
     1441 gatgtcatgg gtaaatatca cccacacggg gattcctcta tttatgaagc catggtccgt
     1501 atggctcaat ggtggagcta ccgttacatg cttgtagatg gtcatgggaa ttttggttcc
     1561 atggatggag atagtgctgc cgctcaacgt tataccgagg cacgtatgag caagattgct
     1621 ctggaaatgc ttcgtgatat caacaaaaat acagttgatt tcgttgataa ctatgatgcc
     1681 aatgaacggg aacccttggt cttgccagcg cgttttccaa accttttggt taatggagca
     1741 actggtatcg cggttgggat ggcaaccaat attccacctc ataatctggg tgaaaccatt
     1801 gatgcagtga agttggtcat ggataatcct gaagtgacta ccaaggactt gatggaagtc
     1861 ttgcctggac cagattttcc aactggtgct cttgtcatgg ggaaatcagg tatccataag
     1921 gcttatgaaa caggtaaagg ttcgattgtc ctacgttctc gtacagagat tgaaacgact
     1981 aagactggtc gtgagcgtat cgttgtaaca gaatttcctt acatggtcaa taaaaccaag
     2041 gtgcatgagc atattgttcg cttggttcag gaaaaacgca ttgagggtat cacagcagta
     2101 cgtgatgagt caaaccgtga aggtgttcga tttgttattg aagtcaagcg cgacgcctca
     2161 gccaatgtta ttctcaataa cctcttcaaa atgacccaaa tgcaaaccaa ttttggtttc
     2221 aatatgctcg ctatccaaaa tggtataccg aaaattttgt ctcttcgtca gattttggat
     2281 gcttatatcg agcaccaaaa agaagtggtt gttcgtcgta cacgttttga taaggaaaaa
     2341 gcggaagcgc gcgctcatat cttagaaggt ctcttgattg cgctagacca tatcgacgaa
     2401 gtgattcgta tcatccgtgc tagtgaaacg gatgcggaag ctcaagctga gttgatgagc
     2461 aagtttaagc tttctgaacg tcaaagtcaa gctatccttg atatgcgtct tcgtcgtttg
     2521 acaggtttgg aacgcgataa gattcaatct gagtatgatg acctcttggc tctgattgcg
     2581 gatttagcag atattcttgc taagcctgaa cgtgtttctc aaattatcaa agacgaattg
     2641 gatgaagtta aacgtaaatt ttctgataaa cgccgtacag agttgatggt tggacagatc
     2701 ttgagtctcg aggatgagga cttgattgaa gaatcggatg tcttgattac cctttctaac
     2761 agaggctaca ttaagcgttt ggatcaggac gagttcactg ctcaaaaacg tgggggtcgt
     2821 ggtgtccaag gaacgggagt gaaagatgat gactttgttc gtgagttagt gtcaactagc
     2881 acccatgatc atctgctctt cttcacaaac aagggacgtg tctatcgtct taaaggttat
     2941 gaaattcctg agtatggtcg gactgccaaa gggctaccag tagtcaatct cttgaaattg
     3001 gatgaagatg aaagtattca gacggttatc aatgttgagt ctgatcgcag tgatgatgct
     3061 tatctcttct ttacaacccg tcacggtatt gtgaagagaa ctagtgttaa ggagtttgcc
     3121 aatattcgtc aaaatggtct caaagcgctg aatttaaagg atgaagatga gttaatcaat
     3181 gtcttattga cagaaggaga tatggatatt atcattggta ccaagtttgg ttatgcagtt
     3241 cgctttaatc aatcagccgt tcgtggtatg agccgtatcg ccactggtgt gaaaggtgtt
     3301 aaccttcgtg aaggagacac agttgttggt gccagcttga ttactgatca agatgaggtt
     3361 cttattatca cagaaaaagg atatggtaag cgtacagtcg ctactgaata cccaacaaaa
     3421 ggtcgtggtg gtaagggaat gcagacagct aaaattaccg aaaaaaatgg cttgctggcc
     3481 ggtcttatga ctgttcaagg tgatgaggat ttgatgatta tcactgatac aggtgtcatg
     3541 attcgaacca atcttgccaa tatttcacaa acaggacgtg caactatggg agttaaagta
     3601 atgcgcctgg atcaagatgc tcagatagtg actttcacaa cggttgcggt ggcagaaaaa
     3661 gaagaagttg ggacagaaaa cgaaacagaa ggtgaagcat aatgtctcaa aaaaataata
     3721 aaaagaaaaa caagcgaaaa aatctgctga caaatatcct agcaggattt ctgatattac
     3781 tgtcactggc tttgattttt aatactcaaa ttcgaaatat tttcatagtc tggaatacca
     3841 ataagtatca agttagccag gtatcaaaag aaaaattaga agaaaatcag gatacagaag
     3901 gcaattttga ctttgattct gtcaaagcta tctcttcgga agctgttcta acttctcaat
     3961 gggatgctca aaaattacca gttattgggg gaattgcaat tcctgaattg gaaatgaatt
     4021 tgccgatttt taaaggactt gataatgtta atctcttcta cggagctggt acaatgaaac
     4081 gcgagcaagt aatgggagaa ggaaattata gtctagctag tcaccatatc tttggtgttg
     4141 ataatgctaa taaaatgtta ttttctcctt tagataatgc taaaaatggc atgaagattt
     4201 atctaaccga taaaaataaa gtttatactt atgaaatacg tgaagtcaaa cgtgtgacac
     4261 cggatcgtgt tgatgaagtt gatgatagag atggggtcaa tgaaatcaca ttagtaacct
     4321 gtgaagacct tgctgctaca gaacgtatta ttgtcaaagg tgatttgaaa gaaacaaaag
     4381 attattcaca aacatctgat gaaatcctaa cagctttcaa tcaaccatat aaacaatttt
     4441 attaatacaa atcagtgaaa tcatggattt cactgatttt ttaagatttt cataaaaat
//
LOCUS       DAVHTH010000093         4494 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.093, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000093 DAVHTH010000000
VERSION     DAVHTH010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4494)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4494)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4494
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.093"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            179..868
                     /locus_tag="VVR63_002002"
     CDS             179..868
                     /locus_tag="VVR63_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEU6129967.1"
                     /translation="MARTVVGVAANLCPVDAEGKIIHSSVSCRFAEIIRQVGGLPLVI
                     PVGDESVVRDYVEMIDKLILTGGQNVHPQFYGEKKTVESDDYNLVRDEFELALLKEAL
                     RQNKPIMAICRGVQLVNVAFGGTLNQEIEGHWQGLPFGTSHSIETVEGSVVAKLFGKE
                     SQVNSVHRQSIKDLAPNFRVTAIDSRDQTIEAIESIDEHRIIGLQWHPEFLVNEEDGN
                     LELFEYLLNEL"
     gene            872..1051
                     /locus_tag="VVR63_002003"
     CDS             872..1051
                     /locus_tag="VVR63_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6129968.1"
                     /translation="MEHLVVLSFIFSKFLECGILRKRLNSDKNWRNSTKKLEKNEGKR
                     YDRKEEILEEEHVTY"
     gene            1038..2387
                     /locus_tag="VVR63_002004"
     CDS             1038..2387
                     /locus_tag="VVR63_002004"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HEU6129969.1"
                     /translation="MSHIKFDYSKVLDKFVAPHEVEYMQSQVTAADELIRKGTGAGSD
                     FLGWLDLPEKYDREEFDRILKAAEQIKSDSDVLVVIGIGGSYLGAKAAIDFLNHHFAN
                     LQTKEERKAPQILYAGNSISSTYLADLVEYVADKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDRQKGAVKVEADANGWGTFVVPDDIGGRFSVLTAVGLL
                     PIAASGADIKALMEGANAARKDYTSDKISENEAYQYAVVRNILYRKGYATEILVNYEP
                     SLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGTRIMFETVVRVDK
                     PRKNVLIPTLEEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGDVPNMYVTLPEQDAF
                     TLGYTIYFFELAIALSGYLNAINPFDQPGVEAYKRNMFALLGKPGFEELSKELNARL"
     gene            2511..3971
                     /locus_tag="VVR63_002005"
     CDS             2511..3971
                     /locus_tag="VVR63_002005"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HEU6129970.1"
                     /translation="MSKDIRVRYAPSPTGLLHIGNARTALFNYLYARHHGGTFLIRIE
                     DTDRKRHVEDGERSQLENLRWLGMDWDESPESHENYRQSERLDLYQKYIDQLLAEGKA
                     YKSYVTEEELAAERERQEVAGETPRYINEYLGMSEEEKAAYIAEREAAGIIPTVRLAV
                     NESGIYKWHDMVKGDIEFEGGNIGGDWVIQKKDGYPTYNFAVVIDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYL
                     PEAVFNFIALLGWNPGGEDEIFSREELIKLFDENRLSKSPAAFDQKKLDWMSNDYIKN
                     ADLETIFEMAKPFLEEAGRLTDKAEKLVELYKPQMKSVDEIIPLTDLFFSDFPELTEA
                     EREVMTGETVPTVLEAFKAKLEAMTDDEFVTENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPDTIFLLGREKSIQHIENILKEISK"
     gene            3985..4416
                     /locus_tag="VVR63_002006"
     CDS             3985..4416
                     /locus_tag="VVR63_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEU6129971.1"
                     /translation="MDIWEKMYEEAQKLYNPHEVSDFVYANHVVAAVEAGDGQIFTGF
                     CMEGTCGVFHLCAERATLFNMYQFSGQTKVKKVLAFRDKPPYGGSSAMPCGACREFLL
                     ELNAENKDAEFMMDYNIRKTVKVAELIPYWWGEERASKFNE"
BASE COUNT         1476 a          842 c          951 g         1225 t
ORIGIN      
        1 ttattcagaa ctctatcaca atcaatttgt tttcgaataa gaaagaagtt gtcctatgtg
       61 ggcagctttt tcttgtccat aaaaaatgtt tatcacagcc ttaaaaaaaa catattagac
      121 gaaagtcatt ttgagtgata tgataggact atcgttagta ttcgaaagga gaggcatcat
      181 ggctagaacg gttgtaggag ttgctgcaaa tctatgtccc gtagacgcag aaggcaaaat
      241 cattcattca tctgtatctt gtagattcgc agagatcatt cgtcaagtcg gtggtctccc
      301 tttagtcatt cctgttggtg atgagtcagt tgtacgtgat tatgtggaaa tgattgacaa
      361 actcattttg acaggaggcc aaaatgttca tcctcagttt tatggagaga aaaagaccgt
      421 cgaaagcgat gattacaatc tggtccgtga cgaatttgaa ttggcactct tgaaggaagc
      481 gcttcgtcag aataaaccaa ttatggcaat ctgtcgcggt gtccaacttg tcaatgttgc
      541 ctttggtgga accctcaatc aagaaatcga aggtcactgg caaggactac ctttcgggac
      601 atctcactct attgaaacag tagaaggaag cgtggtggct aagctatttg ggaaagaaag
      661 tcaggtcaac tcagtccatc gtcaaagcat taaagatttg gcacctaatt tccgtgtaac
      721 tgctattgat tcaagagacc aaactattga agcgattgag tctatcgacg agcaccgcat
      781 tatcggttta cagtggcatc cagagtttct ggttaatgaa gaagatggca atttagaatt
      841 atttgagtat ttattgaatg aactgtaacg attggaacat ctggtcgttc tttcttttat
      901 tttttcaaaa tttttagaat gtggcatttt acgcaaacgt ttgaattctg ataaaaattg
      961 gagaaattcg acaaaaaaac ttgaaaaaaa cgaaggtaag cgttatgata gaaaagaaga
     1021 aatattggag gaagaacatg tcacatatta aatttgatta ttcaaaagtt ttagacaaat
     1081 ttgttgcacc acatgaagtg gaatacatgc aatcacaagt aacagcagca gatgaattga
     1141 tccgtaaagg aactggtgct ggtagcgact tcttgggatg gttggacctt cctgaaaaat
     1201 acgaccgcga agaatttgac cgcatcttga aagctgctga gcaaatcaag tcagacagcg
     1261 atgttttggt tgtgatcggt attggtggat cttaccttgg tgcaaaagca gcaatcgact
     1321 tcttgaatca ccattttgct aacttgcaaa caaaagaaga acgcaaagct ccacaaatcc
     1381 tttacgcagg aaactcaatc tcatctactt accttgctga cttggtagag tatgttgcag
     1441 acaaagactt ctcagtaaac gtaatttcta aatcaggtac aacaactgaa ccagcgattg
     1501 ctttccgtgt ctttaaagaa ctcttggtta agaaatacgg tcaagaagaa gctaacaaac
     1561 gtatctatgc aacaactgac cgccaaaagg gtgctgttaa ggttgaagca gacgctaacg
     1621 gttggggaac atttgttgtt ccagatgata tcggtggacg cttctcagta ttgacagccg
     1681 ttggtttgct tccaatcgca gcatcaggag ctgacatcaa agctcttatg gaaggtgcga
     1741 atgcagctcg caaagactac acttcagaca aaatctctga aaacgaagct taccaatacg
     1801 cagtcgttcg taacatcctt tatcgtaaag gctatgcaac tgagatcttg gtaaactatg
     1861 agccatcact tcaatacttc tcagaatggt ggaaacaatt ggctggtgaa tcagaaggaa
     1921 aagaccaaaa aggtatctac ccaacttcag ccaacttctc aactgacttg cactcacttg
     1981 gtcaatttat ccaagaagga actcgtatca tgtttgaaac agttgtccgt gttgacaaac
     2041 ctcgtaaaaa cgtgcttatt cctactttgg aagaagacct tgacggactt ggttaccttc
     2101 aaggaaaaga cgttgacttt gtaaacaaaa aagcaactga cggtgttctt cttgcccaca
     2161 cagatggtga tgtaccaaac atgtatgtga ctcttccaga gcaagacgct ttcactcttg
     2221 gttacactat ctacttcttc gaattggcaa ttgccctttc aggttacttg aatgctatca
     2281 acccatttga ccaaccaggt gttgaagctt ataaacgtaa catgtttgcc cttcttggaa
     2341 aaccaggatt tgaagaattg agcaaagaac ttaacgcacg tctataatag aagaaaagag
     2401 tggtttgccc actcttttta ctctctttat ccatagaaat tggactcagc caagacttgt
     2461 gatataatat agaaagcaaa aaggcagacg cctagataat aggagaaact atgtcaaaag
     2521 atatccgcgt acgttacgca ccaagtccaa caggactact acacatcgga aatgcccgta
     2581 cagcattgtt taactacttg tatgcgcgcc atcatggtgg aacatttctc atccgtatcg
     2641 aagatactga ccgtaaacgc catgtcgagg atggtgaacg ttcacaactt gaaaaccttc
     2701 gctggttagg catggattgg gatgaaagtc cagaatcaca tgagaattat cgccagtctg
     2761 agcgtttgga cttgtatcaa aaatacattg accaactatt agctgaagga aaagcctata
     2821 aatcttacgt tacagaagaa gagttggcag ctgaacgtga acgtcaagaa gtagctggcg
     2881 aaacaccacg ctacatcaat gaataccttg gtatgagtga agaagaaaaa gcggcttata
     2941 tcgcagaacg tgaagcagct ggtatcatac caacagttcg tttggctgtc aatgagtcag
     3001 gtatctacaa gtggcatgat atggtcaaag gtgatatcga atttgaaggt ggcaatatcg
     3061 gcggtgactg ggttatccaa aagaaagacg gttacccaac ttacaacttt gccgttgtta
     3121 tcgatgacca cgatatgcaa atctctcatg ttatccgtgg agatgaccat attgctaata
     3181 caccaaaaca gcttatggtc tatgaagctc ttggttggga agctccagag tttggtcaca
     3241 tgaccttgat tatcaactct gagactggta agaagttatc taaacgtgat actaatacac
     3301 ttcaatttat cgaagattac cgaaagaaag gttaccttcc agaagcagtc tttaacttta
     3361 ttgctcttct tggttggaac ccaggtggtg aagatgagat tttctctcgt gaagaactca
     3421 ttaaactttt tgatgaaaac cgcctcagca agtcaccagc agcctttgat cagaaaaaat
     3481 tagactggat gagcaatgat tatatcaaga atgcagacct tgaaaccatc tttgaaatgg
     3541 caaaaccatt cttagaggaa gcaggccgtt tgactgacaa ggctgaaaaa ttagttgagc
     3601 tctataaacc acaaatgaaa tcagtagatg agattatccc attgacagat cttttcttct
     3661 cagatttccc agaattgaca gaagcagagc gcgaagtcat gacgggtgaa acagttccaa
     3721 cagttcttga agcattcaaa gcaaaacttg aagcgatgac agatgatgaa tttgtgacag
     3781 aaaatatctt cccacaaatt aaagcagtcc aaaaagaaac aggtattaaa gggaaaaatc
     3841 ttttcatgcc tattcgtatc gcagtttcag gcgaaatgca tgggccagaa ttaccagata
     3901 caattttctt gcttggacgt gaaaaatcaa ttcagcatat cgaaaacatt ctaaaagaaa
     3961 tctctaaata aagaggatac aataatggac atctgggaaa agatgtacga agaagcacag
     4021 aaactataca atccacatga agtatcagac tttgtttatg ccaatcatgt tgtagctgca
     4081 gtagaagcag gagatggaca aatatttaca ggattctgta tggagggaac ctgtggtgtt
     4141 ttccatctct gcgcagaacg ggcgaccctc ttcaatatgt accaattttc aggacaaact
     4201 aaggttaaga aagtattagc ctttcgagac aaaccacctt atggtggaag ttcagccatg
     4261 ccttgcggtg cttgtagaga attcctttta gagcttaatg ctgaaaataa agatgcagaa
     4321 ttcatgatgg actataatat aagaaaaaca gttaaagtcg cagaactaat cccttattgg
     4381 tggggagaag aacgtgcttc taagtttaat gagtgataga agagtcagta taattctggc
     4441 tctttttact ataagttgaa aaaataaaaa aaattagaaa aagtagttga caaa
//
LOCUS       DAVHTH010000094         4479 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.094, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000094 DAVHTH010000000
VERSION     DAVHTH010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4479)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4479)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4479
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.094"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            434..886
                     /locus_tag="VVR63_002007"
     CDS             434..886
                     /locus_tag="VVR63_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEU6129972.1"
                     /translation="MIITKISRLGTYVGVNPHFATLIDFLEKTGLENLTEGSIAIDGN
                     RLFGNCFTYLADGQAGAFFETHQKYLDIHLVLENEEAMAVTSPENVSVTQEYDEEKDI
                     ELYTGKVEQLVHLRAGECLITFPEDLHQPKVRINDEPVKKVVFKVAIS"
     gene            905..2242
                     /locus_tag="VVR63_002008"
     CDS             905..2242
                     /locus_tag="VVR63_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HEU6129973.1"
                     /translation="MKKMRKFLCLAGIALAAVALVACSGKKEATTSTEPPTELSGEIT
                     MWHSFTQGPRLESIQKSADAFMQKHPKTKIKIETFSWNDFYTKWTTGLANGNVPDIST
                     ALPNQVMEMVNSDALVPLNDSIKRIGQDKFNETALNEAKIGDDYYSVPLYSHAQVMWV
                     RTDLLKEHNIGVPKTWDQLYEASKKLKEAGVYGLSVPFGTNDLMATRFLNFYVRSGGG
                     SLLTKDLKADLTSQLAQDGIKYWVKLYKEISPQDSLNFNVLQQATLFYQGKTAFDFNS
                     GFHIGGINANSPQLIDSIDAYPIPKIKESDKDQGIETSNIPMVVWKNSKHPEVAKAFL
                     EALYNEEDYVKFLDSTPVGMLPTIKGISDSAAYKENETRKKFKHAEEVITEAVKKGTA
                     IGYENGPSVQAGMLTNQHIIEQMFQDIITNGTDPMKAAKEAEKQLNDLFEAVQ"
     gene            2321..3205
                     /locus_tag="VVR63_002009"
     CDS             2321..3205
                     /locus_tag="VVR63_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU6129974.1"
                     /translation="MVKERNLTRWIFVLPAMIIVGLLFVYPFFSSIFYSFTNKHLIMP
                     NYKFVGLANYKVVLSDPNFFNAFFNSIKWTVFSLVGQVLVGFVLALALHRVRHFKKLY
                     RTLLIVPWAFPTIVIAFSWQWILNGVYGYLPNLIVKLGLMEHTPAFLTDSTWAFLCLV
                     FINIWFGAPMIMVNVLSALQTVPEEQFEAAKIDGASSWQVFKFIVFPHIKVVVGLLVV
                     LRTVWIFNNFDIIYLITGGGPANATTTLPIFAYNLGWGTKLLGRASAVTVLLFIFLVA
                     ICFIYFAIISKWEKEGRK"
     gene            3205..4038
                     /locus_tag="VVR63_002010"
     CDS             3205..4038
                     /locus_tag="VVR63_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU6129975.1"
                     /translation="MKKKSSIYLDILSHVLLVGATIVAIFPLVWIIISSVKGKGELTQ
                     YPTRFWPEQFTLDYFTHVINDLHFIDNIRNSLIIALATTLIAIIISAMAAYGIVRFFP
                     KLGAIMSRLLVITYIFPPILLAIPYSIAIAKVGLTNSLFGLMMVYLSFSVPYAVWLLV
                     GFFQTVPIGIEEAARIDGANKFVTFYKVVLPIVAPGIVATAIYTFINAWNEFLYALIL
                     INNTGKMTVAVALRSLNGSEILDWGDMMAASVIVVLPSIIFFSIIQNKIASGLSEGSV
                     K"
     gene            4056..>4479
                     /locus_tag="VVR63_002011"
     CDS             4056..>4479
                     /locus_tag="VVR63_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sialidase"
                     /protein_id="HEU6129976.1"
                     /translation="MNKRGLYSKLGISVVGISLLMGVPTLIHANELNYGQLSISPIFQ
                     GGSYQLNNKSIDISPLLLDKLSGESQTVVMKFKADEPNSLQALFGLSNSKAGFKNNYF
                     SIFMRDSGEIGVEIRDAQKGINYLFSRPASLWGKHKGQA"
BASE COUNT         1453 a          724 c          893 g         1409 t
ORIGIN      
        1 ttagaaaaac gaagtgagca gcttataaat tcaagtcccc aaatagattc atactagtat
       61 cttttgcaaa aaataaaggg cgacttccgt catgaatatc aatttcatct ataaggaagg
      121 tagctaattg aactaactta tttattctgt ttgtcgctag aaaaatcaga cctccttgtg
      181 aagattgagg agatactgaa tgaaaatcaa agaagaaact agcaagctag tagcagattg
      241 cccaaaacac cgccttgagg ttgtagataa gactgaccta tataatccaa ggtgaagcga
      301 ctgtggtttg aagagatttt caaagagtat aggctagaga gtagtgtttt tatgtccttc
      361 tagtagaaaa tgctagacag aagaatgggg aacttggata ggaaaaatag attgagaaag
      421 gaggttagaa gagatgatta ttacaaaaat tagccgttta ggaacttatg tgggagtaaa
      481 tccacatttt gcaacattaa tagattttct agaaaaaaca ggactagaaa atttaacaga
      541 aggttcgatt gctatcgatg gtaatcgatt gtttgggaat tgctttactt atctagcaga
      601 tggtcaagca ggggctttct ttgaaacaca ccaaaaatat ttggatattc atttagtttt
      661 ggaaaacgaa gaagccatgg ctgttacatc gccggaaaat gtaagcgtta cccaagaata
      721 tgatgaagag aaagatattg aattatacac agggaaagtg gaacagttgg ttcatttgag
      781 agctggcgaa tgcctcatca cttttccaga agatttacat caacccaagg ttcgtataaa
      841 tgatgaacct gtgaaaaaag ttgtctttaa agttgcgatt tcttaatgta gaaagagaag
      901 aacgatgaaa aaaatgagaa agtttttatg tctagctgga attgcgctag cggctgttgc
      961 cttggtagct tgttcaggaa aaaaagaagc tacaactagt actgaaccac caacagaatt
     1021 atctggtgag attacaatgt ggcactcctt tactcaagga ccccgtttag aaagtattca
     1081 aaaatcagca gatgctttca tgcaaaagca tccaaaaacg aaaatcaaga ttgaaacatt
     1141 ttcttggaat gacttctata ctaaatggac tacaggttta gcaaatggaa atgtgccaga
     1201 tatcagtaca gctcttccta accaagtaat ggaaatggtc aactcagatg ctttggttcc
     1261 gctaaatgat tctatcaagc gtattggaca agataaattt aacgaaactg ccttaaatga
     1321 agcaaaaatc ggagatgatt actactctgt tcctctttat tcacatgcac aagtcatgtg
     1381 ggttagaaca gatttgttaa aagaacataa tattggggtt cctaaaactt gggatcaact
     1441 ctatgaagct tctaaaaaat tgaaagaagc tggagtttat ggcttgtctg ttccgtttgg
     1501 aacaaatgac ttaatggcaa cacgtttctt gaacttctac gtacgtagtg gtggaggaag
     1561 cctcttaaca aaagatctta aagcagactt gacaagccaa cttgctcaag atggtattaa
     1621 atactgggtt aaattgtata aagaaatctc acctcaagat tctttgaatt ttaatgtcct
     1681 tcaacaagct accttgttct atcaaggaaa aacagcattt gactttaact ctggcttcca
     1741 tatcggagga attaatgcca acagtcctca attgattgat tcgattgatg cttatcctat
     1801 tccaaaaatc aaagagtctg ataaagacca aggaattgaa acctcaaaca ttccaatggt
     1861 tgtttggaaa aattcaaaac atccagaagt tgctaaagca ttcttagaag cactttataa
     1921 tgaagaagac tacgttaaat tccttgattc aactccagta ggtatgttgc caactattaa
     1981 ggggattagc gattctgcag cctataaaga aaatgaaact cgtaagaagt ttaaacatgc
     2041 tgaagaagta attactgaag ctgttaaaaa aggtactgct attggttatg aaaatggacc
     2101 aagtgtacaa gctggtatgt tgactaacca acacattatt gaacaaatgt tccaagatat
     2161 cattacaaat ggaacagatc ctatgaaagc agcaaaagaa gcagaaaaac aattaaacga
     2221 tttatttgag gctgttcagt agatgtaaaa gactagaaaa taggtgggct agtgagctga
     2281 aaagctctag cccaatcttg taaaagaagg gagaaggaga atggttaaag aacgtaattt
     2341 aactcgctgg atatttgttt tgccagctat gattatcgta ggattactct ttgtttatcc
     2401 gtttttctcg agtatttttt atagctttac caataagcat ttgattatgc ctaattataa
     2461 atttgttggt ttggctaact ataaagttgt gctatcagat cccaacttct ttaatgcgtt
     2521 ctttaattca attaagtgga ccgttttctc attagttggt caagttttag tagggtttgt
     2581 attggcttta gctcttcaca gagtacgcca cttcaagaaa ttatatagga ccttattgat
     2641 tgttccttgg gcatttccta ccatcgtcat tgccttttct tggcagtgga ttctaaacgg
     2701 ggtttatggc tacttaccta atctaatcgt aaaattaggt ttaatggaac atacacctgc
     2761 atttttgaca gatagtacat gggcattcct atgtttggtg tttatcaaca tttggtttgg
     2821 agcaccaatg attatggtta atgtgctttc agctttgcaa acagtaccag aagaacaatt
     2881 tgaggctgct aagatagatg gtgcttcaag ttggcaggtg ttcaagttta tcgtctttcc
     2941 acatattaaa gtggttgtag gacttctagt tgttttgaga actgtatgga tctttaataa
     3001 ctttgacatt atctacctca ttactggtgg tggaccagcc aatgctacaa cgacgcttcc
     3061 aatttttgct tacaacctgg gctggggaac taaattgttg ggtcgtgctt cagcagttac
     3121 agtattgctc tttatcttct tggtggcgat ttgctttatc tactttgcta tcatcagtaa
     3181 gtgggaaaag gagggtagaa aataatgaag aagaaatcca gtatttattt agatattctc
     3241 tcacatgtac ttttagttgg tgcgaccatc gttgcaattt tcccattggt atggattatc
     3301 atatcttctg tcaaagggaa aggggaatta actcagtatc caacacgatt ttggcctgaa
     3361 cagtttacat tagattattt cactcatgtt atcaacgatt tgcacttcat tgataacatt
     3421 cgaaacagtt taatcattgc cttggctaca accctcattg cgattattat ttctgctatg
     3481 gcagcctatg gtattgttcg attctttcct aaattgggag caatcatgtc gagactactc
     3541 gtcattacct acattttccc accaattttg ttagcaattc cctattcaat tgccattgct
     3601 aaagttgggt taacaaatag tttatttggc ttgatgatgg tttatctatc ttttagtgtt
     3661 ccatatgcag tttggctctt agttggattt ttccaaacag ttccaattgg aattgaagaa
     3721 gcggctagaa ttgatggtgc aaataaattt gttacgtttt ataaagttgt gctaccgatt
     3781 gtagcaccag gtattgtagc aacagctatt tatacattta tcaatgcttg gaatgaattc
     3841 ctgtatgcct tgattttgat taacaataca ggaaagatga cagtagcagt agcccttcgt
     3901 tcacttaatg gttcagaaat actagactgg ggagatatga tggcagcgtc tgttattgta
     3961 gttcttccat caattatttt cttctctatc atccaaaata agattgcaag tggattatca
     4021 gaaggatctg tgaagtagac gaaagaagga aaaaaatgaa taaaagaggt ctttattcaa
     4081 aactaggaat ttctgttgta ggcattagtc ttttaatggg agtccccact ttgattcatg
     4141 cgaatgaatt aaactatggt caactgtcca tatctcctat ttttcaagga ggctcatatc
     4201 aactgaacaa taagagtata gatatcagcc ctttgttatt agataaattg tctggagaga
     4261 gtcagacagt agtaatgaaa tttaaagcag atgaaccaaa ctctcttcaa gctttgtttg
     4321 gcctatctaa tagtaaagca ggctttaaaa ataattactt ttcaattttc atgagagatt
     4381 ctggtgagat aggtgtagaa ataagagacg cccaaaaggg aataaattat ttattttcca
     4441 gaccagcttc attatgggga aaacataaag gacaggcag
//
LOCUS       DAVHTH010000095         4364 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.095, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000095 DAVHTH010000000
VERSION     DAVHTH010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4364)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4364)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4364
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.095"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            468..1589
                     /gene="mnmA"
                     /locus_tag="VVR63_002012"
     CDS             468..1589
                     /gene="mnmA"
                     /locus_tag="VVR63_002012"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HEU6129977.1"
                     /translation="MSDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVVAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAITLGADYVATGHYARVARDEDGTVHMLRGVDNGKDQTYFLSQLS
                     QEQLQKTMFPLGHLEKPEVRKLAEEAGLSTAKKKDSTGICFIGEKNFKNFLSNYLPAQ
                     PGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNAPWFVVGKDLSKNILYVGQ
                     GFYHDSLMSTSLEASQVHFTREMPEEFTLECTAKFRYRQPDSKVTVHVKGDKAEVIFA
                     EPQRAITPGQAVVFYDGEECLGGGLIDNAYRDGQVCQYI"
     gene            1730..2185
                     /locus_tag="VVR63_002013"
     CDS             1730..2185
                     /locus_tag="VVR63_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU6129978.1"
                     /translation="MTQQDFRTKVDNTVFGVRATALILQNRKLLVTKDKGKYYIIGGA
                     IQVNEKTEDAVVREVKEELGVKSQAGQLAFVVENRFEVDGVSYHNIEFHYLVDLLEDA
                     PLTMQEDEKRQPCEWIDLDKLEDIQLVPAFLKTALPDWEGQLRHIHLEE"
     gene            2195..4108
                     /gene="mnmG"
                     /locus_tag="VVR63_002014"
     CDS             2195..4108
                     /gene="mnmG"
                     /locus_tag="VVR63_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HEU6129979.1"
                     /translation="MTYHFTEEYDIIVIGAGHAGVEASLAASRMGCKVLLATINIEML
                     AFMPCNPSIGGSAKGIVVREVDALGGEMAKTIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KELYSKEMRKTVENQENLTLRQTMIDEILVEDGKVVGVRTATHQEYAAKAVIVTTGTA
                     LRGEIIIGDLKYSSGPNHSLASINLADNLKELGLEIGRFKTGTPPRVKASSINYDVTE
                     IQPGDEAPNHFSYTSRDEDYVKDQVPCWLTYTNGTSHEIIQNNLHRAPMFTGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGRNTEEVYVQGLSTSLPEDVQRDLVHSIKGL
                     ENAEMMRTGYAIEYDMILPHQLRATLETKKISGLFTAGQTNGTSGYEEAAGQGIIAGI
                     NAALKIQDKPELILKRSDGYIGVMIDDLVTKGTIEPYRLLTSRAEYRLILRHDNADMR
                     LTEMGREIGLVDDERWARFEIKKNQFDNEMKRLDSIKLKPVKETNAKVEEMGFKPLTD
                     AVTAKEFLRRPEVSYQDVVAFIGPAAEDLDDKIIELIETEIKYEGYISKAMDQVAKMK
                     RMEEKRIPANIDWDDIDSIATEARQKFKLINPETIGQASRISGVNPADISILMVYLEG
                     KNRSISKTLQKSK"
BASE COUNT         1265 a          891 c         1063 g         1145 t
ORIGIN      
        1 aggtgccctt gcagtcaaca caactgtaga tggctatgaa gtcaatgcca atggtgaatg
       61 ggtttaagcc gattaaatta aatcatgtta agaacatttg acattttaat tttgaaacaa
      121 agataaggtt cgattgaata gatttatgtt cgtattcttt aggtacctgt cttatgattt
      181 caggaaatgt cataaaaaaa acgactcctt ttctctaact tgaaaaatag attagagaaa
      241 atgggttgtt ttatttatta tagttatttg aatgaagata agaagaaggt atactcacgt
      301 cattcacata atctgtatat tgactataag ttttaaaaaa caatttttaa gctcttcctt
      361 gtcttctcta accaagcgtg ttataatgaa tactgctcaa gcgaccttca atcgtgaagc
      421 acacacgacc ttcaatcgtg aataaacgaa tagatgggag acttaccatg agtgataact
      481 ctaaaacacg tgttgtcgtg gggatgagtg gtggtgttga ttcgtcggtg acggctcttt
      541 tgctcaagga gcagggctac gatgtgatcg gtatcttcat gaagaactgg gatgacacag
      601 atgaaaacgg cgtctgtacg gcgaccgaag attacaagga tgtggttgcg gtggcagacc
      661 agattggcat tccctactac tctgtcaatt ttgaaaaaga gtactgggac cgcgtttttg
      721 agtatttcct agcggaatac cgtgcagggc gcacgccaaa tccggacgtt atgtgcaaca
      781 aggaaatcaa gttcaaggcc tttttggact atgccataac cttgggggca gactatgtag
      841 cgactgggca ttatgctcga gtggcgcgtg atgaggacgg cactgttcac atgcttcgtg
      901 gcgtggacaa tggcaaggac cagacctatt tcctcagcca actttcgcaa gaacaacttc
      961 aaaaaaccat gttcccacta ggacatttgg aaaagcctga agttcgaaaa ctagcagaag
     1021 aagcaggcct ttcgactgct aagaagaaag actcgacagg gatttgcttt atcggagaaa
     1081 agaactttaa aaactttctc agcaactacc tgccagctca gcctggtcgc atgatgactg
     1141 tggatggtcg cgatatgggc gagcatgcag gtcttatgta ctatacaatc ggtcagcgtg
     1201 gcggactcgg tatcggtggg caacacggcg gtgacaatgc cccttggttc gttgtcggaa
     1261 aagatctaag caagaatatt ctctatgtag gacaaggatt ctaccatgat tcgctcatgt
     1321 caactagcct agaagccagt caagtccact ttactcgtga aatgccagaa gagtttacgc
     1381 tagaatgtac ggctaaattc cgttaccgtc agcctgactc taaggtgacc gtccatgtca
     1441 aaggagacaa ggcagaagtt atctttgcgg aaccacaacg cgcgattaca ccaggacagg
     1501 cagttgtctt ttacgatggc gaagagtgtc taggtggcgg tttgattgac aatgcttacc
     1561 gcgatggaca agtttgtcag tacatttaga ttgacaaatt ttctcaattt gctacaataa
     1621 taacagcaat agaaatgatg gtcaaagctc atggatgttg caggcttttt tgtcctgcac
     1681 ttctttgtag ttttgactgt ttttgtgtcg tttaagggaa aggacaagaa tgactcaaca
     1741 agactttcgg acaaaagtag acaatacggt ttttggtgtt cgggcgacag ctttgattct
     1801 tcaaaatcgc aagcttctag tcaccaaaga caagggcaag tattacatta tcggcggtgc
     1861 gattcaagtt aacgaaaaaa cggaagacgc ggtagtccgt gaagtgaagg aagaactggg
     1921 tgttaaatct caagctgggc agctagcttt tgtggttgaa aatcgttttg aagtggacgg
     1981 cgtttcctat cacaatatcg agtttcatta tctggtggat ttgcttgaag atgccccgtt
     2041 gaccatgcag gaagatgaga aaaggcagcc ctgtgagtgg attgacttgg ataagcttga
     2101 ggatatccag ctagttccag cctttttaaa aacggcccta ccagattggg aaggccaact
     2161 aagacacatt catcttgagg aataggagag aaacatgact tatcatttta ctgaagaata
     2221 cgatattatt gtaattggtg cgggacacgc tggggttgag gcttccttgg ccgctagccg
     2281 tatgggctgt aaggtcctgc ttgcgaccat caatattgaa atgctggctt tcatgccttg
     2341 taatccctct atcggtggtt ctgccaaggg gattgtcgtg cgtgaagtcg atgccctcgg
     2401 tggcgagatg gccaaaacca ttgacaagac ttacatccag atgaagatgc taaacacagg
     2461 gaaggggcca gctgtccgtg cccttcgtgc gcaggctgac aaggaacttt actctaagga
     2521 gatgcgcaag acggttgaaa accaagaaaa tctgaccctt cgtcaaacca tgattgatga
     2581 gattttggtg gaagatggca aggttgtcgg tgtgcgtaca gccacccatc aagaatatgc
     2641 tgctaaggct gttattgtga cgacagggac tgctctccgt ggggaaatta tcatcggaga
     2701 cctcaagtac tcatcaggtc ctaaccacag cttggcttct attaacctag ctgacaatct
     2761 caaggaactg ggcctcgaaa tcggtcgttt caagacagga acccctccac gtgtcaaggc
     2821 ttcttctatc aattacgatg tgacagaaat ccaaccagga gatgaagcac ctaatcactt
     2881 ctcatacact tcacgtgatg aggattatgt caaggaccaa gtgccatgct ggttgaccta
     2941 caccaatggt accagtcatg agattatcca aaacaacctc caccgtgcgc ctatgtttac
     3001 aggtgtggtc aagggagtgg gacctcgtta ctgtccatcg attgaggaca agattgtgcg
     3061 ctttgcggac aaggaacgtc accaactctt ccttgagcca gaaggacgca atacagagga
     3121 ggtctatgtc caaggacttt caaccagtct gcctgaggat gtccaacgtg acttggttca
     3181 ttccatcaaa ggtctggaaa atgcagagat gatgcgaaca ggttatgcta ttgagtatga
     3241 catgatcttg cctcaccagt tgcgtgcgac tttggaaacc aagaaaatct caggactttt
     3301 cactgctggt cagacaaatg gaacatcagg ttacgaagag gcagcaggcc aagggattat
     3361 cgcagggatc aatgcggctc tgaaaatcca agataagcct gagttgattt tgaagcgtag
     3421 tgacggttac attggggtca tgattgatga tttggtgacc aagggaacca tcgaacccta
     3481 ccgtctcttg accagtcgtg ctgaataccg tctcattctc cgtcatgaca atgctgatat
     3541 gcgcttgact gagatgggac gcgagattgg ccttgtggat gatgaacgct gggctcgttt
     3601 tgaaatcaag aaaaatcaat ttgataatga gatgaaacgc ctagacagta tcaaactcaa
     3661 gccagtcaag gaaaccaatg ctaaggttga ggagatgggc ttcaaaccct tgacagatgc
     3721 agtgacagcc aaggaattcc ttcgccgtcc agaagtttct taccaagatg tggtagcctt
     3781 catcggacca gctgcagagg atttggatga taagattatc gaattgattg aaacagaaat
     3841 caagtacgaa ggctatattt caaaagccat ggatcaggtt gccaagatga aacgtatgga
     3901 agaaaaacgc attccagcca atattgactg ggatgacatc gattctattg cgacggaagc
     3961 tcgtcagaag ttcaaactca tcaatccaga aaccatcggc caagccagcc gtatttcggg
     4021 ggtaaaccca gcagatattt ctattttgat ggtgtatctg gaaggtaaaa atcgtagtat
     4081 ttctaaaact cttcaaaaat caaaatgata cgtcgtcggc ttcttacgaa tgagttcaaa
     4141 gcttggcttt gattcatctc cagcctccca tagtttcccg aactatggga gctaactcaa
     4201 gttatgcatt ttcctagcct tctggtctga ttttcattga gttttaatct caaaagaaag
     4261 catagagaaa aacagctccg aagacggggc tgttttgttg acttgtactc aatgaaaatc
     4321 aaagagcaaa ctaggaagct agccgtaggt tgctcaaagc actg
//
LOCUS       DAVHTH010000096         4256 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.096, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000096 DAVHTH010000000
VERSION     DAVHTH010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4256)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4256)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4256
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.096"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            complement(19..732)
                     /gene="rsmG"
                     /locus_tag="VVR63_002015"
     CDS             complement(19..732)
                     /gene="rsmG"
                     /locus_tag="VVR63_002015"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HEU6129980.1"
                     /translation="MKPETFYNLLAEQNLPLSDQQKEQFERYFELLVEWNEKINLTAI
                     TDKEEVYLKHFYDSIAPILQGLIPNETIKLLDIGAGAGFPSLPMKILYPELDVTIIDS
                     LNKRINFLQLLAQELDLNGVHFYHGRAEDFAQDKNFRAQYDFVTARAVARMQVLSELT
                     IPYLKVGGKLLALKASNAPEELLEAKNALNLLFSKVEDNLSYALPNRDPRYITVVEKK
                     KETPNKYPRKAGMPNKRPL"
     gene            826..1386
                     /locus_tag="VVR63_002016"
     CDS             826..1386
                     /locus_tag="VVR63_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HEU6129981.1"
                     /translation="MTWIILGVIALIVIFVIVSYNGLVKNRMQTKEAWSQIDVQLKRR
                     NDLLPNLIETVKGYAKYEGSTLEKVAELRNQVAAATSPAEAMKASDALTRQVSGIFAV
                     AESYPDLKASANFVKLQEELTNTENKISYSRQLYNSVVSNYNVKLETFPSNIIAGMFG
                     FKAADFLQTPEEEKSVPKVDFSGLGD"
     gene            1388..2287
                     /gene="htpX"
                     /locus_tag="VVR63_002017"
     CDS             1388..2287
                     /gene="htpX"
                     /locus_tag="VVR63_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HEU6129982.1"
                     /translation="MLFDQIASNKRKTWILLLVFFLLLALVGYAVGYLFIRSGLGGLV
                     IALIIGFIYALSMIFQSTEIVMSMNGAREVDEQTAPDLYHVVEDMALVAQIPMPRVFI
                     IDDPALNAFATGSNPQNAAVAATSGLLAIMNREELEAVMGHEVSHIRNYDIRISTIAV
                     ALASAITMLSSMAGRMMWWGGAGRRRSDDDRDGNGLEIIMLVVSLLAIVLAPLAATLV
                     QLAISRQREFLADASSVELTRNPQGMINALDKLDNSKPMSRHVDDASSALYINDPKKG
                     GGFQKLFYTHPPISERIERLKHM"
     gene            complement(2436..3995)
                     /locus_tag="VVR63_002018"
     CDS             complement(2436..3995)
                     /locus_tag="VVR63_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEU6129983.1"
                     /translation="MHYRHSRKGNSMIKINHLTITQNKDLRDLVSDLSMTIQDGEKVA
                     IIGEEGNGKSTLLKTLMGEDLSDFTIKGDIQSDYQSLAYIPQKLPEELKKKTLHDYFF
                     LDSIDLDYSILYRLAEELHFDSNRFASDQEIGNLSGGEALKIQLIHELAKPFEILFLD
                     EPSNDLDLETVDWLKGQIQKTRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLV
                     EHLDYDSYSEQRKANFAKQSQQAANNQRAYDKTMEKHRRVKQNVETALRATKDSTAGR
                     LLAKKMKTVLSQEKRYEKAAQSMTQKPLEEEQIQLFFSDIQPLPASKVLVQLEKGNLS
                     IDDRVLVQKLQLTVRGQEKIGIIGPNGVGKSTLLAKLQRLLNDKREISLGFMPQDYHK
                     KLQLDLSPIAYLSKTGEKEELQKIQSHLASLNFSYPEMQHQIRSLSGGQQGKLLLLDL
                     VLRKPNFLLLDEPTRNFSPTSQPQIRKLFATYPGGLITVSHDRRFLKEVCSIIYRMTE
                     HGLKLVNLEDL"
BASE COUNT         1186 a          804 c          900 g         1366 t
ORIGIN      
        1 atttgtttac taaaaaattt aaagtgggcg tttatttggc ataccagcct tacgtggata
       61 tttatttggt gtttcttttt tcttttctac cactgtgata tagcgcggat ctctattcgg
      121 tagggcgtag ctgagattgt cttcgacctt actaaaaagg agattgaggg cattcttagc
      181 ttctaacaac tcctcaggcg cattgctagc cttgagtgct aatagtttgc caccaacctt
      241 aaggtaggga atagtcaatt cagataggac ctgcatacgg gcaaccgcac gagctgttac
      301 aaaatcatat tgagcacgga agttcttgtc ttgggcaaaa tcttcggcac gtccgtggta
      361 gaaatgaact ccgttcaaat ccagttcttg agccaagagt tgtaggaagt tgatgcgctt
      421 attgagtgaa tcaataatgg tcacatctaa ctccggatag agaattttca ttggtagact
      481 aggaaatcct gccccagccc cgatatcaag aagtttgata gtttcattgg gaatcaaacc
      541 ttgaagaatg ggtgcaatcg aatcgtaaaa atgtttgaga taaacttctt ccttgtccgt
      601 aatcgccgtc aaattaatct tctcattcca ctcgaccaag agctcaaaat aacgttcaaa
      661 ttgttctttt tgctggtccg aaagtggaag attctgctcg gcaagcaagt tgtaaaatgt
      721 ttctggtttc atagttattt ccttctttag tatcatctta ttttaccaca atcattaaaa
      781 atttgatata ctggtactaa tctaaaagta gaaaggactt atatcatgac ttggattatt
      841 cttggagtta tcgctcttat tgttattttt gtgattgtta gctataacgg tttggttaaa
      901 aatcgtatgc aaaccaagga ggcttggagt cagattgatg ttcagttgaa acgtcgaaat
      961 gacctcttgc caaacttgat tgagactgta aaaggttatg ccaaatatga aggttctacc
     1021 cttgaaaagg tggcagaact acgtaaccaa gtggcggcag cgacttcacc agcagaagct
     1081 atgaaagcca gtgatgccct cactcgtcaa gtttcaggta tttttgcagt tgcagaaagc
     1141 tatccagatt tgaaagctag tgctaacttt gttaaattgc aagaggagtt gacaaacaca
     1201 gaaaataaaa tttcttactc tcgtcaactc tataacagtg ttgtcagcaa ctacaatgta
     1261 aaattagaaa ctttcccgag caatattatc gctggaatgt ttggatttaa agcggcagat
     1321 ttccttcaaa cacctgaaga ggaaaagtcg gttcctaaag ttgattttag cggtttaggt
     1381 gactaagatg ttgtttgatc aaattgcaag caataaacga aaaacctgga ttttgttgct
     1441 ggtatttttc ctactcttag ctcttgttgg ttatgcggtt ggttatctct ttataagatc
     1501 tggacttggt ggtttggtta tcgcactgat tatcggcttt atctacgctt tgtctatgat
     1561 ttttcaatcg acagagattg tcatgtccat gaatggagcg cgtgaggtgg atgagcaaac
     1621 ggcaccagac ctctaccatg tagtggaaga tatggctctg gtcgctcaga ttcctatgcc
     1681 ccgtgttttc atcattgatg atccagcctt aaatgccttt gcgacaggtt ctaatcctca
     1741 aaatgcggct gttgctgcga cttcaggtct actagctatc atgaatcgtg aagaactaga
     1801 agctgttatg ggacatgaag tcagtcatat tcgtaattat gatatccgta tttcgactat
     1861 tgcagttgcc cttgctagtg ctatcaccat gctttctagt atggcaggtc gtatgatgtg
     1921 gtggggtgga gcaggtcgca gacgaagtga tgatgaccga gatggaaatg gtcttgaaat
     1981 cattatgcta gtggtttccc tactagctat tgtactggca cctctcgctg caaccttggt
     2041 tcagctcgct atttctcgtc agagggaatt tctggcagat gcatctagtg tcgagctgac
     2101 tcgcaatccc cagggaatga ttaatgccct agataagttg gacaatagca aacctatgag
     2161 tcgccacgtc gatgatgcta gcagtgccct ttatatcaat gatcccaaga aaggtggggg
     2221 gttccaaaaa ctcttttata cccacccacc tatctcagaa cggattgaac gtttaaaaca
     2281 tatgtaaaat gaaggctgga aaaaagtctt taaaatctga aaaacgcata atatcaggtg
     2341 tgaaaacttg atattatgcg ttttactatg ggaagattta cttctttttc tcctaaaatt
     2401 gtgtttttgc cccacctatc tgctatgttg caaatttata aatcttctaa attaactagc
     2461 ttcaaaccgt gttctgtcat gcgatagatg atcgagcaga cttcttttaa gaaacgacgg
     2521 tcatgcgaaa cagtgatgag accgccagga taagtggcaa agagttttct gatttggggt
     2581 tgagaagtgg gagaaaagtt tcgtgtgggt tcatccagca ggagaaagtt tggtttgcgc
     2641 aggactaaat ccaaaagcag gagttttccc tgttgtccgc cagataagga gcgaatttga
     2701 tgctgcattt ctggataact gaaattgaga ctagctaggt gagattggat tttctgtagt
     2761 tcctcttttt ccccagtttt actgagatag gctattgggg ataaatccaa ttgcagtttt
     2821 ttgtggtaat cttgtggcat aaaaccaagt gaaatctctc ttttatcatt cagaagtctc
     2881 tgtaacttgg ctaacagagt tgatttccca acaccatttg gcccgataat accgattttt
     2941 tcttggccac ggacagttag ttgtagtttt tgaaccaaaa ctcggtcgtc aatggacaaa
     3001 tttccttttt ccagttggac taagacttta gaagctggta atggttggat gtctgaaaag
     3061 aaaagttgga tttgttcctc ttcaagtggt ttttgagtca tggactgagc tgccttttcg
     3121 tagcgttttt cttgtgagag gacagttttc atctttttag ccaataggcg accggcagta
     3181 ctatctttgg tagctcgaag cgcagtttct acattttgct taactctccg atgtttttcc
     3241 atggttttat cgtaggctct ttggttgtta gcagcttgct gactttgttt ggcaaaatta
     3301 gcctttctct gctcactata gctatcatag tctaaatgct ctactagcgt ttccgcttct
     3361 ttacggtgtt tgaccagtcg caagtgaaca atagtgtctg ccgtttcaga aagaaagtct
     3421 tcatcatggg aaatgaaaat aacggtttgc ctggtctttt gaatctggcc ttttagccaa
     3481 tcaactgtct caaggtctag gtcatttgaa ggttcatcta aaaatagaat ctcaaagggt
     3541 ttggctaact catggataag ctgaattttc aaagcttctc cccctgatag attgccaatc
     3601 tcttggtcac ttgcgaaacg attgctatca aaatgcaatt cctccgccaa acgatagagg
     3661 atactgtagt ctaaatcaat agaatctaaa aagaagtagt cgtgtaaagt tttctttttc
     3721 agctcctcgg gaagtttttg aggaatgtag gccagtgact gatagtcaga ttggatgtct
     3781 cccttgatag tgaaatcaga caaatcttcc cccattaaag ttttaagtaa ggttgattta
     3841 ccatttcctt cttcgccaat aatagctacc ttttccccgt cttgtatggt catgcttagg
     3901 tcagagacaa ggtctcgtaa atctttgttt tgtgtgatgg tcaggtgatt gatttttatc
     3961 atactattgc cctttctaga atgtcgatag tgcataacaa aaagctctac tttacctagt
     4021 agagcccaaa gtctatgtca aaaaaactct attaacatgc cagaaaaaga gcataaaaga
     4081 gcacacaaaa agagacaaaa acaagatcta ctaaataaag gttctttatt tgatagactt
     4141 agttgttcat gtctccctta cctccgagta ttagtatctt tatattatac ctttaaggaa
     4201 attttgtcaa cagaaaactg gaaattctat gctctaaaat ccaaaaacag gtccat
//
LOCUS       DAVHTH010000097         4136 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.097, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000097 DAVHTH010000000
VERSION     DAVHTH010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4136)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4136)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4136
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.097"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            371..598
                     /locus_tag="VVR63_002019"
     CDS             371..598
                     /locus_tag="VVR63_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6129984.1"
                     /translation="MIFKAFKTKKQRKRQVELLLTVFFDSFLIDLFLHLFGIVPFKLD
                     KILIVSLIIFPIISTSIYAYEKLFEKVFDKD"
     gene            886..3783
                     /gene="nanA"
                     /locus_tag="VVR63_002020"
     CDS             886..3783
                     /gene="nanA"
                     /locus_tag="VVR63_002020"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored neuraminidase NanA"
                     /protein_id="HEU6129985.1"
                     /translation="MNRSVQERKCRYSIRKLSVGAVSMIVGAVVFGTSPVLAQEGASE
                     QPLANETQLSGESSTLTDTEKSQPSSETELSGNKQEQERKDKQEEKIPRDYYARDLEN
                     VETVIEKEDVETNASNGQRVDLSSELDKLKKLENATVHMEFKPDAKAPAFYNLFSVSS
                     ATKKDEYFTMAVYNNTATLEGRGSDGKQFYGNYNDAPLKVKPGQWNSVTFTVEKPTPE
                     LPKGRVRLYVNGVLSRTSLKSGNFIKDMPDVTHVQIGATKRANNTVWGSNLQIRNLTV
                     YNRALTPEEVQKRSQLFKRSDLEKKLPEGAVLTEKTDIFESGRNGKPNKDGIKSYRIP
                     ALLKTDKGTLIAGADERRLHSSDWGDIGMVIRRSEDNGKTWGDRVTITNLRDNPKAFD
                     PSIGSPVNIDMVLVQDPETKRIFSIYDMFPEGKGIFGMSSQKEEAYKKIDGKTYQILY
                     REGEKGAYTIRENGTVYTPDGKATDYRVVVDPVKPAYSDKGDLYKGNQLLGNIYFTTN
                     KTSPFRIAKDSYLWMSYSDDDGKTWSAPQDITPMVKADWMKFLGVGPGTGIVLRNGPH
                     KGRILIPVYTTNNVSHLNGSQSSRVIYSDDHGKTWHAGEAVNDNRQVDGQKIHSSTMN
                     NKRAQNTESTVVQLNNGDVKLFMRGLTGDLQVATSKDGGVTWEKDIKRYPQVKDVYVQ
                     MSAIHTMHNGKEYIILSNAGGPNRENGMVHLARVEENGELTWLKHNPIQKGEFAYNSL
                     QELGNGEYGILYEHTEKGQNAYTLSFRKFNWEFLSKDLISPTEAKVKRTREMGKGEMG
                     KGVIGLEFDSEVLVNKAPTLQLANGKTATFLTQYDSKTLLFAVDKEDIGQEIIGIAKG
                     SIESMHNLPVNLAGARVPGGVNGSKAAVHEVPEFTGGVNGTEPAVHEIAEYKGSDSLV
                     TLTTKEDYTYKAPLAQQALPETGNKESDLLASLGLTAFFLGLFTLGKKREQ"
BASE COUNT         1410 a          682 c          897 g         1147 t
ORIGIN      
        1 gtcagtctta tccacaacct caaaacagtg ttttgagcat catgcggcta gcttcttagt
       61 ttgctctttg attttcattg agtataaaaa cagatgagtt tctgttttct ttttatggac
      121 tataaatgtt cagctgaaac tactttcaag gacattatta tataaaagaa ttttttgaaa
      181 ctaaaatcta ctatattaca ctatattgaa agcgttttaa aaatgaggta taataaattt
      241 actaacactt ataaaaagtg atagaatcta tctttatgta tatttaaaga tagattgctg
      301 taaaaatagt agtagctatg cgaaataaca gatagagaga agggattgaa gcttagaaaa
      361 ggggaataat atgatattta aggcattcaa gacaaaaaag cagagaaaaa gacaagttga
      421 actacttttg acagtttttt tcgacagttt tctgattgat ttatttcttc acttatttgg
      481 gattgtcccc tttaagctgg ataagattct gattgtgagc ttgattatat ttcccattat
      541 ttctacaagt atttatgctt atgaaaagct atttgaaaaa gtgttcgata aggattgagc
      601 aggaagtatg gtataaatag cataagctga tgtccatcat ttgcttataa agagatattt
      661 tagtttaatt gcagcggtgt cctggtagat aaactagatt ggcaggagtc tgattggaga
      721 aaggagaggg gaaaattggc accaatttga gatagtttgt ttagttcatt tttgtcattt
      781 aaatgaactg tagtaaaaga aagttaataa aagacaaact aagtgcattt tctggagtaa
      841 atgtcttatt tcagaaatcg ggatatagat atagagagga tcagtatgaa tcggagtgtt
      901 caagaacgta agtgtcgtta tagcattagg aaactatcgg taggagcggt ttctatgatt
      961 gtaggagcag tggtatttgg aacgtctcct gttttagctc aagaaggggc aagtgagcaa
     1021 cctctggcaa atgaaactca actttcgggg gagagctcaa ccctaactga tacagaaaag
     1081 agccagcctt cttcagagac tgaactttct ggcaataagc aagaacaaga aaggaaagat
     1141 aagcaagaag aaaaaattcc aagagattac tatgcacgag atttggaaaa tgtcgaaaca
     1201 gtgatagaaa aagaagatgt tgaaaccaat gcttcaaatg gtcagagagt tgatttatca
     1261 agtgaactag ataaactaaa gaaacttgaa aacgcaacag ttcacatgga gtttaagcca
     1321 gatgccaagg ctccagcatt ctataatctc ttttctgtgt caagtgctac taaaaaagat
     1381 gagtacttca ctatggcagt ttacaataat actgctactc tagaggggcg tggttcggat
     1441 gggaaacagt tttacggtaa ttacaacgat gcacccttaa aagttaaacc aggtcagtgg
     1501 aattctgtga ctttcacagt tgaaaaaccg acaccagaac tacctaaagg ccgagtgcgc
     1561 ctctacgtaa acggggtatt atctcgaaca agtctgaaat ctggcaattt cattaaagat
     1621 atgccagatg taacgcatgt acaaatcgga gcaaccaagc gtgccaacaa tacggtttgg
     1681 gggtcaaatc tacagattcg gaatctcact gtgtataatc gtgctttaac accagaagag
     1741 gtacaaaaac gtagtcaact ttttaaacgc tcagatttag aaaaaaaact acctgaagga
     1801 gcggttttaa cagagaaaac ggacatattc gaaagcgggc gtaacggtaa accaaataaa
     1861 gatggaatca agagttatcg tattccagca cttctcaaga cagataaagg aactttgatc
     1921 gcaggtgcag atgaacgccg tctccattcg agtgactggg gtgatatcgg tatggtcatc
     1981 agacgtagtg aagataatgg taaaacttgg ggtgaccgag taaccattac caacttacgt
     2041 gacaatccaa aagcttttga cccatcgatc ggttcaccag tgaatatcga tatggtgttg
     2101 gttcaagatc ctgaaaccaa acgaatcttt tctatctatg acatgttccc agaagggaag
     2161 ggaatctttg gaatgtcttc acaaaaagaa gaagcctaca aaaaaatcga tggaaaaacc
     2221 tatcaaatcc tctatcgtga aggagaaaag ggagcttata ccattcgaga aaatggtact
     2281 gtctatacac cagatggtaa ggcgacagac tatcgcgttg ttgtagatcc tgttaaacca
     2341 gcctatagcg acaagggtga tctatacaag ggtaaccaat tactaggcaa tatctacttc
     2401 acaacaaaca aaacttctcc atttagaatt gccaaggata gctatctatg gatgtcctac
     2461 agtgatgacg acgggaagac atggtcagcg cctcaagata ttactccgat ggtcaaagcc
     2521 gattggatga aattcttggg tgtaggtcct ggaacaggaa ttgtacttcg gaatgggcct
     2581 cacaagggac ggattttgat accggtttat acgactaata atgtatctca cttaaatggc
     2641 tcgcaatctt ctcgtgtcat ctattcagat gatcatggaa aaacttggca tgctggagaa
     2701 gcggtcaacg ataaccgtca ggtagacggt caaaagatcc actcttctac gatgaacaat
     2761 aaacgtgcgc aaaatacaga atcaacggtg gtacaactaa acaatggaga tgttaaactc
     2821 tttatgcgtg gtttgactgg agatcttcag gttgctacaa gtaaagacgg aggagtgact
     2881 tgggagaagg atatcaaacg ttatccacag gttaaagatg tctatgttca aatgtctgct
     2941 atccatacga tgcataatgg aaaagaatac attatcctca gcaatgcagg tggaccgaat
     3001 cgtgaaaatg ggatggtcca cttggcacgt gtcgaagaaa atggtgagtt gacttggctc
     3061 aaacacaatc caattcaaaa aggagagttt gcctataatt cgctccaaga attaggaaat
     3121 ggggagtatg gcatcttgta tgaacatact gaaaaaggac aaaatgccta taccctatca
     3181 tttagaaaat ttaattggga atttttgagc aaagatctga tttctcctac cgaagcgaaa
     3241 gtgaagcgaa ctagagagat gggcaaagga gagatgggca aaggagttat tggcttggag
     3301 tttgactcag aagtattggt caacaaggct ccaacccttc aattggcaaa tggtaaaaca
     3361 gcgactttcc taacccagta tgatagcaag accttgttgt ttgcagtaga taaggaagat
     3421 atcggacagg aaattattgg tatagctaaa ggaagcatcg aaagtatgca taatcttcct
     3481 gtaaatctag caggtgccag agttcctggc ggagtaaatg gtagcaaagc agcggtgcat
     3541 gaagttccag aatttacagg gggagttaat ggtacagagc cagctgttca tgaaatcgca
     3601 gagtataagg gatctgattc gcttgtaact cttactacaa aagaagatta tacttacaaa
     3661 gctcctcttg ctcagcaggc acttcctgaa acaggaaaca aggagagtga cctcctagct
     3721 tcactaggac taacagcttt cttccttggt ctgtttacgc tagggaaaaa gagagaacaa
     3781 taagagaaga attctaaaca tttgattttg taaaaataga aggagatagc aggttttcaa
     3841 gcctgctatc tttttttgat gacattcagg ctgatacgaa atcataagag gtctgaaact
     3901 actttcagag tagtctgttc tataaaatat agtagattga aataagatgt gaacaactct
     3961 atcaggaaag tcaaattaat ttatagaaaa attttagcag tcaaggtgta ctgttataga
     4021 ttcaatatat tatgtgacta ttaaccttct cttctcctaa aattgacttt cttgttttct
     4081 tatcttgtcc actcgaaaca agtattgtaa gaatttgatt atttttgaaa gtactt
//
LOCUS       DAVHTH010000098         4129 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.098, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000098 DAVHTH010000000
VERSION     DAVHTH010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4129)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4129)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4129
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.098"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            713..1705
                     /locus_tag="VVR63_002021"
     CDS             713..1705
                     /locus_tag="VVR63_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU6129986.1"
                     /translation="MAMIEVEHLQKHFVKIVKEPGLKGALRSFIHPEKQTFEAVKDLT
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGFCRINGKIPQDNRQDYVKDIGVV
                     FGQRTQLWWDLALQETYTVLKEIYDVPNSLFHKRMDFLNEVLDLKDFIKDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINQEEETTILLTTHDLS
                     DIEQLCDRIFMIDKGQKIFDGTVSQLKETFGKMKTLSFELLPGQSHLVSHYEGLSDMT
                     IDRQGNSLNIEFDSSRYQSADIIKQTLSDFEIRDLKMVDTDIEDIIRRFYRKEL"
     gene            1707..2525
                     /locus_tag="VVR63_002022"
     CDS             1707..2525
                     /locus_tag="VVR63_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HEU6129987.1"
                     /translation="MIKLWRRYKPFINAGVQELITYRVNFILYRIGDVMGAFVAFYLW
                     KAVFDSSQESLIQGFSMADITLYIIMSFVTNLLTRSDSSFMIGEEVKDGSIIMRLLRP
                     VHFAASYLFTELGSKWLIFISVGLPFLSVIVLMKIISGQGIVEVLGLTVLYLFSLTLA
                     YLINFFFNICFGFSAFVFKNLWGSNLLKTSIVAFMSGSLIPLAFFPKVVSDILSFLPF
                     SSLIYTPVMIIVGKYDASQILQALLLQFFWLLVMVGLSQLIWKRVQSFITIQGG"
     gene            2527..3312
                     /locus_tag="VVR63_002023"
     CDS             2527..3312
                     /locus_tag="VVR63_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6129988.1"
                     /translation="MKKYQRMHLIFIRQYIKQIMEYKVDFVVGVLGVFLAQGLNLLFL
                     NVIFQHIPFLEGWTFQEIAFIYGFSLIPKGMDHLFFDNLWALGQRLVRKGEFDKYLTR
                     PINPLFHILVETFQIDALGELLVGGILLGTTVTSIVWTLPKFLLFLVCIPFATLIYTS
                     LKIATASIAFWTKQSGAMIYIFYMFNDFAKYPISIYNSLLRWLISFIVPFAFTAYYPA
                     SYFLQEKDVFFNVGGLMLISLVFFVISLKLWDKGLDSYESAGS"
     gene            3410..3628
                     /locus_tag="VVR63_002024"
     CDS             3410..3628
                     /locus_tag="VVR63_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
                     /protein_id="HEU6129989.1"
                     /translation="MKDLPEWFGIPESTQAYIEGTTTLQVWTAYQESDLTGFVRLSYS
                     SEDCAEIDCLGVKKLIKVEKLGANCLLL"
     gene            3613..3774
                     /locus_tag="VVR63_002025"
     CDS             3613..3774
                     /locus_tag="VVR63_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HEU6129990.1"
                     /translation="MLATLESEARKKVGYLQVKTVAEGSNKDYDRTNDFYRGLGFKKL
                     EIFSQLWNP"
BASE COUNT         1151 a          702 c          895 g         1381 t
ORIGIN      
        1 attatggtat cgaatcttca tcagaatgat aaaattaatc aattaatatc tgattacaaa
       61 cagaatatga aagcttttta tatcactatt gaaaaattta tacgagatga tgaaagcctt
      121 aagtgttatt ttacaaaggt tatttcaagt cgttccaagg taacaagtct agatcagatt
      181 gaagctgata aaacgataca aagaaaatat tcaagtgagc taaaaaaatt tattggattt
      241 tataatgaga ttatttgtga ggaaaatagt ttcctacatg tacgaaagag gtggtcgagt
      301 tggtttaggt agtcggtgcg tgagttgata attctcaggg tatggacttc tttttcatga
      361 atgaggtaaa agagcaggta ttgtttagag acaatcattc tgagcatatt ttctggatag
      421 agggagtatc cgattttatg atcaaagtta ataccgccct ctggtgagaa gatgagtagg
      481 ttggtaattt aaactattaa acagaatttt tgattaaaag tattatttca tgagagaaat
      541 cctaatttca caatctatag gcaaacgctt gcatttcgtt ttttattgga ctataatagg
      601 ttggtataaa gccttctgta gtaataaaat gtagaaggtg tagaaagtaa ggatttagaa
      661 tatttgtagt taaaaacaca atgttgctat tccttacgat agggagatag atatggcaat
      721 gatagaagtg gaacatcttc agaaacattt tgtgaagatt gttaaggaac cgggcttgaa
      781 gggggctttg cgctccttta ttcatcctga aaagcagacc tttgaagcgg tcaaggattt
      841 gacctttgag gttccaaaag ggcagatttt aggatttatc ggggcaaatg gtgctgggaa
      901 gtcgacaacc attaaaatgc tgacaggaat tttgaaacca acatctggtt tttgtcggat
      961 taacggcaag attccccagg acaatcggca agattatgtc aaagatattg gcgtagtctt
     1021 tggacaacgc acccagctat ggtgggattt ggctctgcaa gagacctaca ctgtcttaaa
     1081 agagatttat gatgtgccaa actcgctctt tcataagcgt atggactttt tgaatgaagt
     1141 cttggatttg aaggacttta tcaaggatcc cgtgcggact ctttcactgg gacaacggat
     1201 gcgagcggat attgcggcct ccttgctcca caatcccaag gttctttttt tagatgagcc
     1261 gaccattggt ttggacgttt cggttaagga taatattcgt cgggcaatta ctcagatcaa
     1321 tcaagaggaa gaaactacca ttcttttgac cactcacgat ttgagtgata ttgagcaact
     1381 ttgtgatcgg attttcatga ttgacaaggg gcaaaagatt tttgatggaa cggtgagcca
     1441 actcaaggag acctttggta agatgaagac tctctctttt gaactgctac caggtcaaag
     1501 tcatctcgtc tctcactatg aaggtctgtc tgatatgacc attgatagac aaggaaacag
     1561 cctcaacatt gaatttgata gttctcgcta ccagtcagct gacattatca agcaaaccct
     1621 atctgatttt gaaatccgcg atttgaagat ggtggatacg gatattgagg atattatccg
     1681 tcgcttctac cgaaaggagc tctaggatga tcaaattgtg gagacgttat aaacccttta
     1741 tcaatgcagg ggttcaggag ttgattactt accgagtcaa ctttattctc tatcggattg
     1801 gcgatgtcat gggggctttt gtggcctttt atctctggaa ggctgtcttt gattcttcgc
     1861 aagagtcttt gattcagggc ttcagtatgg cggatatcac cctctacatc atcatgagtt
     1921 ttgtgaccaa tcttctgact agatccgatt cgtcctttat gattggggag gaggtcaagg
     1981 atggctccat tatcatgcgt ttgttgcgac cagtgcattt tgcggcctcc tatcttttca
     2041 ccgagcttgg ttccaagtgg ttgattttta tcagcgttgg ccttccattt ttaagtgtca
     2101 ttgtcttgat gaaaatcata tcgggtcaag gtattgtaga ggtgctagga ttaactgtcc
     2161 tttatctttt tagcttaacg ctcgcctatc tgattaactt tttctttaat atttgctttg
     2221 gattttcagc ctttgtgttt aaaaatcttt ggggttccaa cctacttaag acttccatag
     2281 tggcttttat gtcggggagt ttgattccct tggcattctt tccaaaggtt gtttcagata
     2341 ttctctcctt tttgcctttt tcgtccttga tttatactcc agttatgatc attgttggaa
     2401 aatacgatgc cagtcagatt cttcaggcac tccttttgca gttcttctgg ctcttagtga
     2461 tggtgggatt gtctcagtta atttggaaac gggtccagtc ctttatcacc attcaaggag
     2521 gttagtatga aaaaatatca acgaatgcat ctgattttta tcagacaata catcaaacaa
     2581 atcatggaat ataaggtgga ttttgtggtt ggtgtcttgg gagtctttct ggctcaaggc
     2641 ttgaatctct tgtttctcaa tgtcatcttt caacatattc cattcctaga aggctggacc
     2701 tttcaagaga tagctttcat ttatggattt tccttgattc ccaagggaat ggaccatctc
     2761 ttttttgaca atctctgggc actagggcaa cgcctagtcc gaaaaggaga gtttgacaag
     2821 tatctgactc gtcccatcaa tcctctcttt cacatcctag ttgaaacctt tcagattgat
     2881 gccttgggtg aactcttagt cggtggtatt ttattgggaa caacagtgac cagcattgtt
     2941 tggactcttc caaaattcct gcttttccta gtttgtattc cttttgcgac cttgatttat
     3001 acttctctta aaatcgcaac agccagtatc gccttttgga ctaagcagtc aggcgccatg
     3061 atttacatct tctatatgtt caatgacttt gctaagtatc cgatttctat ttacaattct
     3121 cttcttcgtt ggttgattag ctttatcgtg cctttcgcct ttacagccta ctatccagct
     3181 agctatttct tacaggaaaa ggatgtgttc tttaacgtag gaggtttgat gttgatttct
     3241 ctggttttct ttgttatttc ccttaaactt tgggataagg gcttagattc ctacgaaagt
     3301 gcgggttcgt aaaagctaaa gtaagactaa aatcaagaaa ggaacttatg atgtttgtaa
     3361 ttgaagaagt caaggatgaa aatcaaaaaa ggcagttgtc gttgaggttt tgaaggattt
     3421 gccagaatgg tttggaatcc cagaaagcac acaagcctat atagaaggaa ccacgacact
     3481 gcaagtttgg accgcctatc aggagagtga tttgactgga tttgtaaggt tatcctattc
     3541 gagtgaagat tgtgcagaga ttgattgtct cggcgtaaaa aagcttatca aggtagaaaa
     3601 attgggagcc aattgcttgc tactttagag agtgaagctc gtaaaaaagt tggttatctg
     3661 caggtcaaaa cagtggcaga aggttctaat aaagattatg atcgaacaaa tgacttttat
     3721 cgaggtcttg gctttaaaaa gttagagatt ttttctcagc tatggaatcc gtaaaatcct
     3781 tgtcagattt tgattaaaaa gcttgaataa tattacttga catctattct cagagtgcca
     3841 tactgtaagt gtaatcgccg atttagctca gttggtagag caaggcactc gtaaagccta
     3901 ggttataggt agataaacga ctgaggagtt gaaaaaatag ataggtagaa gataaccgtt
     3961 aagccttatt cttagcggtt atttatattg tttaatagcg ctgatatttc atcaattatg
     4021 cctgttttcg tgtttctggt agttgttcaa gtttattgct actatttttg atggtatgaa
     4081 tgtgcttata atgtatcccg gttaacgaaa gttttggact tatactcat
//
LOCUS       DAVHTH010000099         3973 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.099, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000099 DAVHTH010000000
VERSION     DAVHTH010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3973)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3973)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3973
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.099"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            1..1099
                     /locus_tag="VVR63_002026"
                     /pseudo
     CDS             1..1099
                     /locus_tag="VVR63_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436265.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1198..2820)
                     /gene="groL"
                     /locus_tag="VVR63_002027"
     CDS             complement(1198..2820)
                     /gene="groL"
                     /locus_tag="VVR63_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166362.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HEU6129991.1"
                     /translation="MSKEIKFSSDARSAMVRGVDILADTVKVTLGPKGRNVVLEKSFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     IKNVTAGANPIGIRRGIETAVAAAVEALKNNAIPVANKEAIAQVAAVSSRSEKVGEYI
                     SEAMEKVGKDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDSEKMVADLENPYI
                     LITDKKISNIQEILPLLESILQSNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATIEALGQAARVTVDKDSTVIVEGA
                     GNPEAISHRVAVIKSQIETTTSEFDREKLQERLAKLSGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALANVIPAVATLELTGDEATGRNIVLRALEEPVRQ
                     IAHNAGFEGSIVIDRLKNAELGIGFNAATGEWVNMIDQGIIDPVKVSRSALQNAASVA
                     SLILTTEAVVANKPEPVAPAPAMDPSMMGGMM"
     gene            complement(2836..3120)
                     /gene="groES"
                     /locus_tag="VVR63_002028"
     CDS             complement(2836..3120)
                     /gene="groES"
                     /locus_tag="VVR63_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HEU6129992.1"
                     /translation="MLKPLGDRLVLKVEEKEQTVGGFVLAGSAQEKTKTAQVVATGQG
                     VRTLNGDLVAPSVKTGDRVLVEAHAGLDVKDGDEKYIIVGEANILAIIEE"
     gene            complement(3276..3671)
                     /locus_tag="VVR63_002029"
     CDS             complement(3276..3671)
                     /locus_tag="VVR63_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEU6129993.1"
                     /translation="MYNKVILIGRLTSTPELHKTNNDKSVARATIAVNRRYKDQNGER
                     EVDFVNMVLWGRLAETLASYATKGSLISVDGELRTRRFEKNGQMNYVTEVLVTGFQLL
                     ESRAQRAMRENNAGQDLADLVLEEEELPF"
     gene            complement(3749..>3973)
                     /locus_tag="VVR63_002030"
     CDS             complement(3749..>3973)
                     /locus_tag="VVR63_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HEU6129994.1"
                     /translation="TTIQPGIVETDFSTVRFHGDKERAASVYQGIEALQAQDIADTVV
                     YVTSQPRRVQITDMTIMANQQATGFMVHKK"
BASE COUNT         1103 a          916 c          726 g         1228 t
ORIGIN      
        1 aaacgccgtt tcaagtgcta tcactgttca aaaatgatgg ttgctgagac tcccctggta
       61 aagaaaaatc accaaatccc tcgtatcatc aaccaaaaaa ttgctcaaaa gttaattgaa
      121 aagatttcta tgactgatat tgcccatcag ctttccatct caacttcaac tgtcattcgc
      181 aagctcaatg attctcactt tgagcatgat ttttcgcgtc ttcctgagat tatgtcctgg
      241 gacgttgaaa cagtccgggg agtgactgtt tcaatcggga gatggagatg agcttcattg
      301 cgcaagattt taacaatctc aatatcatca ctgttcttga gggaagaaca caagctatca
      361 ttcgaaatca ctttcttcgc tacgatagag ctgtccgatg tcgcgtcaaa attattacta
      421 tggatatgtt tagcccttac tatgacttgg ctaaacagct tcgctttcaa atttctaggc
      481 tcaggctgaa acagtctccc agactgtttc actcccgaat gctaaaatcg ttcttgatcg
      541 ctttcacatt gtgcaacatc ttagccgtgc tatgagtcgt gtgcgtgttc aaatcatgaa
      601 tcagtttcat cgaaaatccc atgaatacaa ggctatcaag cgctaatgga agctcataca
      661 acagaatagc cgtaaactga gtgataagcg attttatcgt cctacttttc gtatgcactt
      721 aacaaataaa gaaattcttg acaagatttt aagctattca gaagacttga aacaccacta
      781 tcagatctat caactcttac tttttcactt tcagaacaaa gaccctgaga aatttttcgg
      841 actcattgag gacaatctga agcaggttca tcctattttt cagactgtct ttaaaacctt
      901 cctcaaagat aaagaaaaga ttgtcaacgc ccttcaacta cactattcta atgccaaact
      961 ggaagcgacc aataatctca tcaaacttat caagcgcaat gcctttggtt ttcggaactt
     1021 tgaaaacttc aaaaaacgga tttttatcgc cctgaatatc aaaaaagaaa ggacgaaatt
     1081 tgtcctttct cgagcttagc tgacttcaac ccactacagt tgacaaagag cctataaaaa
     1141 gaagggttag tcattccctc cttttgtgtt ttttataagt tgttttctat agaaagctta
     1201 catcatcccg cccatcatac ttggatccat tgctggagct ggggctactg gttctggttt
     1261 attggctacg actgcttctg ttgtcaaaat caagctggct acagatgctg cattttgtag
     1321 ggctgaacga ctcactttaa ctggatcaat gataccttga tcaatcatgt taacccactc
     1381 gccagttgct gcgttaaatc ctataccaag ctcagcattt ttcaaacgat cgataacgat
     1441 agatccttca aatcctgcat tgtgagcaat ttgacgaacg ggttcttcca aagcacggag
     1501 aacaatatta cgtcctgttg cttcatctcc tgtcaattcc aaggtagcaa cagctggaat
     1561 cacattggca agagctgttc caccgcctgc aacaatacct tcttcaacag ctgcacgagt
     1621 agcgttgagg gcatcttcaa tgcggagttt catttctttc aactcagttt cagttgcggc
     1681 tccgacctta ataaccgcta caccacctga caatttggcc aagcgttctt gcaatttttc
     1741 acggtcaaat tcagaagttg tagtttcgat ttgagacttg ataaccgcaa cacggtgaga
     1801 aatcgcttca ggatttcctg caccttctac aataaccgtg ctatctttgt ccacggtcac
     1861 tctcgctgct tgaccaagag cttcaattgt cgcatctttc aactcaagac caaggtcttc
     1921 tgtgataact gttccgcctg ttaagatggc gatatcttca agcatggctt tgcgacggtc
     1981 accaaaacca ggtgccttga ctgctactac gttgaaggtt ccacgaatct tgttcaaaac
     2041 aagagttgga agagcctcgc catccacatc atccgcaata atcaagagtg gacgattgct
     2101 ttggagaatg ctttccaaaa gtggcaagat ctcttggata ttggaaattt tcttgtctgt
     2161 aatcaaaatg tacggatttt caaggtcagc caccattttt tcgctatctg tcaccatgta
     2221 ctgtgaaagg taaccacggt caaactgcat tccttctacg acttcaagct ctgtttccat
     2281 accacgtgac tcttcgatgg tgatgacacc gtctttgcca actttttcca ttgcttcaga
     2341 gatgtactca ccaacttttt cagaacgaga agatacggct gcaacttgag cgatagcttc
     2401 tttattggca acagggatgg cgttgttttt caaagcttca actgctgcgg caactgctgt
     2461 ttcaatccca cgacgaatac cgattggatt tgcacctgct gtgacgtttt tgattccttc
     2521 acggacgata gcttgggtca agactgttgc agtcgtagtc ccgtcacctg cgatatcatt
     2581 ggttttagaa gctacttctg ataccaattt ggcacccata ttttcaaaat ggtcttctaa
     2641 ttcaatttct ttggcaatag tcacaccgtc attggtaatc aatggtgagc caaatgattt
     2701 ttcaagaacg acattgcgac cttttggtcc caaggttact ttaacagtat ctgcaaggat
     2761 atcgacacca cggaccatag ctgaacgggc atctgatgaa aatttaattt cttttgacat
     2821 acttactttc tccttctatt cttcaatgat tgccaagatg ttagcttcgc ctacgatgat
     2881 atacttttca tcgccatctt tgacatcaag acctgcgtgg gcttcaacta agacacggtc
     2941 tccagtttta acacttggag caaccaagtc accgttcaag gtacgaacac cttgtccagt
     3001 agccacaact tgggctgttt tggttttttc ttgggctgaa cctgcgagaa caaagcctcc
     3061 aacagtttgt tctttttctt ctacttttaa gaccaaacgg tcccctaatg gtttcaacat
     3121 ctgatttcct ccataatgag atagatatta ttagcactct ttatacctga gtgctaattc
     3181 atagttctat tgtatcactt agtcagaaat aatcaagaaa aaagtctgac tttctcaaga
     3241 taaaaagcct gagaccaact cagacttttt aattcttaaa atggcaattc ttcctcttcc
     3301 aagaccaaat ctgccaaatc ttggcctgca ttattttcac gcatagcacg ttgggcacga
     3361 ctttccaaga gttggaatcc tgtcacaagg acttcggtta cataattcat ctgaccattt
     3421 ttctcaaagc gacgggtacg caattctcca tcaacggaaa tgagactacc tttggttgcg
     3481 tagcttgcca aagtttctgc tagtctgccc cataggacca tattgacaaa atcaacttca
     3541 cgttcaccgt tttggtcttt gtaacgacgg ttgacagcga tagttgctcg cgctactgac
     3601 ttgtcattgt tggttttgtg caattctggt gtagacgtta aacgtccaat caagataact
     3661 ttattataca tattttcttc ctcctactta tctattcgta ggaaatcaaa aaaagttaca
     3721 gaaatttgta acttttcgag aaaatttttt attttttatg aaccatgaaa cctgtcgcct
     3781 gttgattggc cataatggtc atatctgtaa tctgaacacg acgaggttga ctagtcacat
     3841 agactactgt atctgcaata tcctgagctt gcaaagcttc tattccttgg taaacggacg
     3901 cagctcgttc tttatcacca tgaaaacgca ctgtagaaaa atctgtttcg acaattccag
     3961 gctgaatggt tgt
//
LOCUS       DAVHTH010000100         3555 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.101, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000100 DAVHTH010000000
VERSION     DAVHTH010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3555)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3555)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3555
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.101"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            complement(78..1007)
                     /locus_tag="VVR63_002031"
     CDS             complement(78..1007)
                     /locus_tag="VVR63_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006154193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEU6129995.1"
                     /translation="MEKIVITATAESIEQVEQLLEAGVDRIYVGEKDFGLRLPTTFSY
                     DQLREIAKLVHDAGKELIVAVNALMHQDMMDRIKPFLDFLEEIKTDYITIGDAGVFYV
                     VNRDGYSFKTIYDASTMVTSSRQINFWGQKAGASEAVLAREIPSAELFKMPEILEIPA
                     EVLVYGASVIHHSKRPLLQNYYNFTHIDDEKTHKRDLFLAEPSDPESHYSIFEDNHGT
                     HIFANNDLDLMIKLTELVEHGFTRWKLEGLYTPGQNFVEIAKLFIQARSLIQEGNFSH
                     DQAFLLDEEVRKLHPKNRFLDTGFYDYDPDMVK"
     gene            1147..1434
                     /locus_tag="VVR63_002032"
     CDS             1147..1434
                     /locus_tag="VVR63_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HEU6129996.1"
                     /translation="MPVRKLQSYEVDYQEELNQQLPHYQAYTPEAQSDANLKEILFFI
                     NIAVFCICIAIFSFIFLALKLSTALAFAAAIGFSLLVLKVQRSIIKRKRRR"
     gene            complement(1468..2802)
                     /gene="ciaH"
                     /locus_tag="VVR63_002033"
     CDS             complement(1468..2802)
                     /gene="ciaH"
                     /locus_tag="VVR63_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CiaH"
                     /protein_id="HEU6129997.1"
                     /translation="MFSKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLY
                     TSVDDKLHGLSENPQAVIQLAINRATEEIKDLENARADASKVEIKPNVSSNTEVILFD
                     KDFTQLLSGNRFLGLDKIKLEKKELGHIYQIQVFNSYGQEEIYRVILMETNISSVSTN
                     IKYAAVLINTSQLEQASQKHEQLIVVVMASFWILSLLASLYLARVSVRPLLESMQKQQ
                     SFVENASHELRTPLAVLQNRLETLFRKPEATIMDVSESIASSLEEVRNMRFLTTSLLN
                     LARRDDGIKPELAEVPTSFFNTTFTNYEMIASENNRVFRFENRIHRTIVTDQLLLKQL
                     MTILFDNAVKYTEEDGEIDFLISATDRNLYLLVSDNGIGISTEDKKKIFDRFYRVDKA
                     RTRQKGGFGLGLSLAKQIVDALKGTVTVKDNKPKGTIFEVKIAIQTPSKKKK"
     gene            complement(2792..3466)
                     /gene="ciaR"
                     /locus_tag="VVR63_002034"
     CDS             complement(2792..3466)
                     /gene="ciaR"
                     /locus_tag="VVR63_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CiaR"
                     /protein_id="HEU6129998.1"
                     /translation="MIKILLIEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGV
                     YDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTAKESLDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRSGKFNENTLTYGNIVVNLSTNTVKVEDTPVELLGKEFDLLVY
                     FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKVRKKLKGTTFAENLQTLRSVGY
                     LLKDVQ"
BASE COUNT         1103 a          747 c          609 g         1096 t
ORIGIN      
        1 ttttaaaata gtgaagaaat acgaaaaatt gagagaagaa atgttttcat cttccttctc
       61 tcaacgaatc atgtatttta tttaaccatg tcaggatcgt agtcataaaa tcctgtatca
      121 aggaaacggt ttttagggtg aagtttacga acttcttcat ccagcaagaa ggcttggtca
      181 tggctaaagt tgccctcttg aatcaagcta cgcgcttgga taaagagttt tgcaatctca
      241 acaaagttct gaccaggagt gtagagccct tctagtttcc agcgagtaaa gccatgctcc
      301 accaattctg ttaatttgat catcaaatca aggtcattgt tggcaaagat atgggtccca
      361 tgattatctt caaaaatgga atagtggctc tctggatcac ttggctcagc caagaagagg
      421 tcacgtttat gcgtcttttc atcatcgata tgtgtaaagt tatagtagtt ttgcaagagt
      481 ggacgtttag aatgatggat gacgctagca ccgtaaacca aaacttcagc aggaatttcc
      541 aaaatctctg gcattttgaa aagttcagct gatggaattt cacgcgccaa aacagcctca
      601 gatgcgccag ccttttgtcc ccagaagtta atctgacgac tgctagttac catggttgaa
      661 gcatcgtaga tggtcttaaa tgaataacca tcgcggttaa ctacgtaaaa gacgcctgca
      721 tccccaatcg taatatagtc tgtcttgatt tcttccaaga agtctaagaa aggcttgata
      781 cggtccatca tatcttggtg catgagagca ttgaccgcaa cgatcaattc cttaccagca
      841 tcatgaacca acttagcgat ttcacgtaat tggtcataac taaaggtcgt tggcagacga
      901 aggccaaaat ctttctcacc gacatagata cggtctacgc cagcttcgag tagttgttca
      961 acttgttcaa tactttcagc agttgctgta atgacaatct tttccataag aaaaattata
     1021 ccacatttct ccaaaatcag ccatgctttg aaaatgaaaa gggactttat tctttttgta
     1081 acctttctgt aataattctc tgccgaaaaa atgataaaat aggtatgtac tgttaaggag
     1141 agaatcatgc ccgtaagaaa attacaatcc tatgaggtag actatcaaga agaattaaac
     1201 cagcagcttc ctcattacca agcttataca cctgaagcgc aatctgatgc caatctcaag
     1261 gaaatcctat tttttattaa tatcgctgtt ttttgtatct gtattgctat ctttagtttt
     1321 atctttttag cattaaaatt atcaactgct cttgcctttg ccgcagcaat cggattcagc
     1381 ttacttgttt taaaagttca acggtctatt atcaaacgaa aacgtagaag ataaatccaa
     1441 aatatcgccc caattggagc gatattttta ttttttcttt ttagatggtg tctgaatggc
     1501 aatcttcact tcaaagattg ttcccttggg tttattatct ttgacagtaa cagttccttt
     1561 tagagcatct acaatttgct tggctaggga taatcctaaa ccaaaaccac ctttttgccg
     1621 ggttctagct ttgtctactc gataaaaacg gtcaaaaatt ttctttttat cttctgtcga
     1681 aataccgatt ccattatcag aaacaagtaa ataaagattg cgatcggtcg ccgagataag
     1741 aaaatcaatt tcaccatcct cctcagtata cttgacggca ttatcgaaaa gaatggtcat
     1801 cagttgtttc agaagaagct gatctgtgac aattgttcga tggatacgat tttcaaaacg
     1861 gaagacacga ttattttccg aagcaatcat ctcatagttt gtgaaagttg tattaaaaaa
     1921 gctagttgga acttctgcaa gctccggctt aatcccatca tctctccgag ctaagttcag
     1981 caagcttgtc gttaaaaaac gcatatttcg gacttcttcc aaactcgatg caatgctttc
     2041 gctcacatcc ataatggtag cttctggctt acgaaaaagg gtctctaagc gattttgcaa
     2101 aactgcgagt ggagttcgta actcatgact ggcattttcc acaaaagact gttgcttctg
     2161 catactctca agcaggggcc taacactgac cctagctaga tagagactgg caagtaaaga
     2221 caaaatccag aaactagcca tcacgaccac aatcaattgc tcatgctttt gactagcctg
     2281 ctccaactga ctggtattaa tcaagacagc agcatacttg atattggttg aaaccgaact
     2341 aatattggtc tccatcaaaa tcacacgata gatttcttcc tgcccatagc tattaaaaac
     2401 ctgaatctgg tagatatgtc ctagttcttt cttttctaac ttaatcttat ccaagcccaa
     2461 aaatcgattt ccagaaagaa gttgagtaaa gtctttatca aagagaatga cttccgtatt
     2521 ggaactgaca ttaggtttta tttctacttt actagcgtcc gccctagcat tttctaaatc
     2581 tttaatctct tctgttgccc tatttatagc cagctgaata actgcttgag gattttcact
     2641 cagtccatga agcttatcgt ccaccgaagt ataaagactc gaatgcatga cttgtaaaat
     2701 aatcagagtc attgtagaaa aaatcagggt gaagacaccg aagttgcgga taaaataact
     2761 aaagtcatcc gcataccatg tttttttaag tttactgaac atcttttaaa agatacccaa
     2821 cactacgcaa ggtttgcaaa ttctctgcaa aagtggttcc ctttaatttc ttacggactt
     2881 ttgaaacata gacttcgaca accgaaatcg ttgtatcact atcaaatccc catagacggt
     2941 caaaaatctg cgtcttaggc aaaatcacat tttgattttg aaggaaataa actagtaaat
     3001 cgaactcttt ccccagcaat tcgacaggag tatcttcaac tttaacggta ttggttgata
     3061 aattaaccac gatattccca taagtcaagg tgttttcatt aaacttccct gaacgtttga
     3121 gaagggcctg aattcgcatt ttaagttctt ctaggtagaa aggtttggtc agataatcat
     3181 ccgctcccag ttcaaatcca tgtcccttgt catccaaact ttccttggca gtcataatca
     3241 gaactggtgt cgtaattccc ttttcacgca attcttttaa gacttggaaa ccattttttt
     3301 ctggcaacat caaatccagc aaaatcaagt catagacacc actctcagct tcgtagagac
     3361 cttcttctcc atcaaatacc tgcataacat ccgcaaaatc gtctaaaaag tcaaatactg
     3421 aatttgacag acctaggtca tcctcaatca ataagatttt tatcatgaga aactcctcct
     3481 tattaaaact attataccaa atttgcctta aaaaaaactc aactctctgc attttacatg
     3541 agatagctga gtttt
//
LOCUS       DAVHTH010000101         3445 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.102, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000101 DAVHTH010000000
VERSION     DAVHTH010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3445)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3445)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3445
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.102"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            <1..270
                     /locus_tag="VVR63_002035"
     CDS             <1..270
                     /locus_tag="VVR63_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6129999.1"
                     /translation="VTHYKYYRAENSHLIYADYFEMKLQKLLKDDTKVFEKSTFKFVE
                     GYKIYLTESKESGIKQMDNVIKYFEFIESKSIALYFQKRLNELID"
     gene            complement(628..1161)
                     /locus_tag="VVR63_002036"
     CDS             complement(628..1161)
                     /locus_tag="VVR63_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HEU6130000.1"
                     /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENAIIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGTSYYCNVASPYYLDEEALKYI
                     DYDLDVKIFTDGEKRLLDVEEYERHKRKMNYSDDLDYILKEHVKILVDWINNGRGPFS
                     EAYVNIWYKRYVELKNR"
     gene            complement(1250..2026)
                     /gene="recX"
                     /locus_tag="VVR63_002037"
     CDS             complement(1250..2026)
                     /gene="recX"
                     /locus_tag="VVR63_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000705102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HEU6130001.1"
                     /translation="MKITKLEKKKRLYLMELDNGDKCYITEDTIVRFMLSRDKVISEE
                     ELKEIQDFAQFSYGKNLALYHLSFKARTEKEVREYLKKYDIDKNIVSQVIANLKEDKW
                     INDGQYAYAIINTNQLSGDKGPYVLTQKLSQKGISKSTIEENLKEFDFSEVAQRVANK
                     LLKKYEGKLPARALQDKIIQNLTNKGFSYSDAKIAFDDLDSQVDQETTQELIFKELDK
                     QYTKYARKYEGYELKQRLTQVLARKGYDFSDIASALREYL"
     gene            2064..3419
                     /gene="rlmD"
                     /locus_tag="VVR63_002038"
     CDS             2064..3419
                     /gene="rlmD"
                     /locus_tag="VVR63_002038"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEU6130002.1"
                     /translation="MNLKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGEDIYC
                     QITSIRRNFVEAKLLKVNKKSKFRIVPSCTIYNECGGCQIMHLHYDKQLEFKTDLLHQ
                     ALKKFAPAGYENYEIRPTIGMQEPKYYRAKLQFQTRKFKNQVKAGLYAQNSHYLVELK
                     DCLVQDKETQVIANRLAELLTYHQIPITDERKVLGVRTIMVRRARKTGQVQIIIVTNR
                     QLNLTQLVKELVKDFPEVVTVAVNTNTAKTSEIYGEKTEIIWGQESIQEGVLNYEFSL
                     SPRAFYQLNPEQTEVLYSEAVKALDVDKEDHLIDAYCGVGTIGFAFAKKVKTLRGMDI
                     IPEAIEDAKRNAKRMGFDNTHYEAGTAEEIIPRWYKEGYRADALIVDPPRTGLDDKLL
                     DTILTYVPEKMVYISCNVSTLARDLVRLVEVYDLHYIQSVDMFPHTARTEAVVKLIKK
                     V"
BASE COUNT         1133 a          581 c          603 g         1128 t
ORIGIN      
        1 gttacccact acaaatatta tagagccgaa aattcacatc taatatatgc agactacttt
       61 gaaatgaaat tacaaaaatt attaaaagat gacacaaaag tttttgaaaa atctacattc
      121 aaatttgtag aaggatataa aatatacctg acagaatcta aagaatctgg aattaaacaa
      181 atggacaatg tcataaaata ttttgagttt attgaatcta aaagtattgc tttatatttt
      241 caaaaacgat taaatgagct gatagattaa atatcatttt ctctgttaag atattgtttt
      301 taaaatattg tactaaatga ttgatgctat gtggaaatac aaaaaaatgt ttttgatacg
      361 aagttgacct gtatttttta tactaatcat tttcgtattt tttgtattaa acgatataag
      421 tttgttgtaa acttactagg aataaagaca ttaaaaaata atagtatatc tatttgtttt
      481 atatatttta cgaattctgc ataaatctct ttctagtaat gtgttgtaac tctgctataa
      541 tggatttatt cctttttgta tttacacaat ttattttata ctaccaaaaa aacaaggtca
      601 ggattttgtt cctgaccttt gacaacttta ccgattcttt agttctacat agcgcttgta
      661 ccaaatgttt acataggctt ctgagaaagg accacgtcca ttgttaatcc aatcaacaag
      721 aattttgaca tgttctttta aaatatagtc caagtcatca gaataattca ttttgcgttt
      781 gtgacgctcg tattcttcaa cgtccaagag acgtttttcc ccatctgtaa aaattttaac
      841 atccaaatcg taatcaatat acttcagtgc ttcttcatcc agatagtagg ggctagccac
      901 attgcaatag taagaagttc cattatcacg aatcatggca atgatattaa accaatattt
      961 cttgtgaaag taaacaatag ccggttctcg agtgacccaa cgacgaccat cactttcggt
     1021 aacaagtgta tgatcgttga caccaataat ggcgttttct gttgttttta gtaccatggt
     1081 gtcccgccaa gttcggtgga gactcccatc atgcttataa ctttgaattg taataaagtc
     1141 gccttctttt ggaagcttca taactaacca actttctaca atttataagt ttatcattta
     1201 ctattgtacc ataaaattac ctaaaatctg tgaatttcac ttggaaatat taaagatatt
     1261 ctctaagagc gcttgctata tccgaaaaat cgtagccctt tcgtgctaaa acttgagtta
     1321 aacgctgctt cagttcgtat ccttcatact ttcgagcata cttagtatat tgcttatcaa
     1381 gttccttgaa gatgagttct tgagtcgttt cttggtcaac ttggctatct aagtcgtcaa
     1441 aggcaatttt agcatcagaa taagagaagc ccttgttagt caagttctgg ataatcttat
     1501 cttgcagggc acgagctgga agttttccct catatttttt caatagttta ttggctacac
     1561 gttgagcaac ttcagaaaaa tcaaattctt tcaagttctc ttctatagta gattttgaaa
     1621 tccctttttg agatagtttc tgagtcagca cataaggacc cttgtctcct gaaagttgat
     1681 tggtattgat gatagcataa gcgtactgac catcattaat ccacttatct tctttaagat
     1741 tagcaataac ttgagaaacg atgtttttat caatatcgta ttttttcaga tattctctga
     1801 cttctttttc agtgcgtgct ttaaaggata agtggtagag agcgagattc ttaccataag
     1861 aaaattgagc aaagtcttga atctctttca attcctcttc gcttatcacc ttatctctcg
     1921 ataacataaa acgaacaatt gtatcttcgg tgatatagca tttgtcgcca ttatcaagct
     1981 ccatcaggta gagtcttttt ttcttttcaa gttttgtgat tttcatagct ctattataac
     2041 tcaaaatgtg ataagatagg ggtatgaatc tgaaagtgaa acaaaaaata ccattaaaaa
     2101 tcaagcgcat gggaattaac ggtgagggaa tcggctttta ccaaaaaaca ttagtctttg
     2161 taccaggagc tctcaaaggc gaagatatct attgtcagat tacttctatt agacgcaact
     2221 ttgttgaagc aaaattactg aaggtcaaca agaagtctaa atttcgaatt gtgccatctt
     2281 gtactattta taatgaatgc ggaggctgcc aaatcatgca cctgcattat gataagcagc
     2341 tggagttcaa gacggactta cttcatcaag cgctgaaaaa atttgctcct gcaggatatg
     2401 aaaattatga aattcgtcca actattggaa tgcaggaacc aaaatattac agagctaagt
     2461 tacaatttca gactcgaaaa tttaaaaatc aggtcaaggc gggcttatat gcacaaaact
     2521 ctcactattt agtagagttg aaagactgcc tggtacaaga taaggaaacc caagtgattg
     2581 ctaatcgctt agcagaatta cttacttatc accagattcc aatcacggat gagagaaaag
     2641 ttctaggtgt ccgtactatt atggtccgac gcgcgagaaa gaccggacag gttcagatta
     2701 ttattgttac aaaccgccag cttaatttaa ctcaattggt aaaagagttg gttaaagatt
     2761 tcccagaagt tgtgacagta gctgttaata caaatacagc taaaaccagt gagatatatg
     2821 gtgaaaagac agagattatc tgggggcaag agagtattca agaaggtgta ctcaattatg
     2881 aattttcact atcccctcga gctttttatc aactaaatcc tgagcaaaca gaagtcctct
     2941 atagcgaagc agtaaaagcg ctggatgttg ataaagaaga ccatttgatt gacgcttatt
     3001 gtggagttgg aacgattgga tttgcctttg caaagaaagt taaaacactc agaggtatgg
     3061 atattattcc agaagctatt gaagatgcca agcgaaatgc taaaagaatg ggatttgaca
     3121 atactcatta tgaagctgga acggcagaag agattattcc tcgttggtac aaggaaggct
     3181 accgagcaga tgctttgatt gttgacccac cacgtacagg tctggatgat aagttattag
     3241 atactattct tacttatgta ccagaaaaaa tggtttatat ttcttgtaat gtttcgacct
     3301 tggctcgtga tttggtacgc ttagtagaag tctatgatct tcattatatc cagtcggtcg
     3361 atatgttccc acatacagct cgaactgaag ctgttgtaaa attaataaaa aaagtttaaa
     3421 aaagtagttg acaaagtttg aaaag
//
LOCUS       DAVHTH010000102         3373 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.103, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000102 DAVHTH010000000
VERSION     DAVHTH010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3373)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3373)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3373
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.103"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            <1..252
                     /locus_tag="VVR63_002039"
     CDS             <1..252
                     /locus_tag="VVR63_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU6130003.1"
                     /translation="QKFLLPTLTTPSVIIMDNARFHRMGKLELLCEEFGHKLLPLPPY
                     SPEYNPIEKTWAHIKKHLKKVLPSCNTFYEALLSCSCFN"
     gene            338..1288
                     /locus_tag="VVR63_002040"
     CDS             338..1288
                     /locus_tag="VVR63_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEU6130004.1"
                     /translation="MGKKRWARNGSESNDASYAQVVSLYDDTSISVSNNETDKVLTGS
                     LYTETNEQGLTIPSSLLKNWNEQTGKNLTTNDLIGKSVSASIVESAAETSKIAQFQTK
                     IVRVINDEDDMEDSNSFMLSHQMETILKEAGFTKAVSYFILELKDPSQTKVVTEELQK
                     NKKYTVLSQQRVLDIVITFIRVIQGLLIVLSSQAIVVAAVMIGIIIYINIMQRSKEIG
                     VMKAVGYQNRGVKGIFIYEAIWIVGIALLLAFLVAQGVGSLANAIVSHFYPSITKVFE
                     LNLLSVLGTLVFALLLGYVSAYFPARKISKMDPVESLRYE"
     gene            1465..2472
                     /gene="gap"
                     /locus_tag="VVR63_002041"
     CDS             1465..2472
                     /gene="gap"
                     /locus_tag="VVR63_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HEU6130005.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPVMLAHL
                     LKYDTTQGRFDGTVEVKEGGFEVNGKFVKVSAERDPEQIDWATDGVEIVLEATGFFAK
                     KEAAEKHLKGGAKKVVITAPGGNDVKTVVFNTNHDVLDGTETVISGASCTTNCLAPMA
                     KALQDNFGVVEGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIG
                     LVIPELNGKLDGSAQRVPTPTGSVTELVAVLEKNVTVDEVNAAMKAASNESYGYTEDP
                     IVSSDIVGMSYGSLFDATQTKVLDVDGKQLVKVVSWYDNEMSYTAQLVRTLEYFAKIA
                     K"
     gene            complement(2540..3295)
                     /locus_tag="VVR63_002042"
     CDS             complement(2540..3295)
                     /locus_tag="VVR63_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000609767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEU6130006.1"
                     /translation="MINQEEVRWNEIVNPGDVCQLTFDEEDYPQKTIPWGNPDLVQEV
                     YQDQHLIIVNKPEGMKTHGNQPNEIALLNHVSTYVGQTCYVVHRLDMETSGLVLFAKN
                     PFILPILNRLLEKKEISREYWALVDGNINRKELVFRDKIGRDRHDRRKRIVDAKNGKY
                     AETHVSRLKQFSNKTSLAHCKLKTGRTHQIRVHLLHHNLPILGDPLYNSKSKTSRLML
                     HAFRLSFTHPLTLERLTFTTLSNTFEKELKKNG"
BASE COUNT         1008 a          606 c          708 g         1051 t
ORIGIN      
        1 cagaagtttc tcttaccaac attaaccaca ccatcggtta ttattatgga taatgcaaga
       61 ttccatagaa tgggtaagtt agaactttta tgcgaggagt ttgggcataa acttttacct
      121 cttcctccct actcacctga gtacaatcct attgagaaaa catgggctca tatcaaaaag
      181 cacctcaaaa aggtattacc aagttgcaat accttttatg aggctctttt gtcctgctct
      241 tgtttcaatt gactatagtt cacggataca gttgggaaag aagctattaa atatttggag
      301 agtccttttg ggatgaacat gtcaaatatt actatagatg ggcaagaaaa gatgggcaag
      361 aaatggatct gagtcaaacg atgcttctta tgctcaagta gtgagtcttt atgatgatac
      421 aagtatctct gttagtaata atgagacgga caaagtgttg actggatccc tctatactga
      481 aacaaatgaa cagggattaa cgattccaag cagtttacta aaaaattgga atgaacagac
      541 aggaaaaaat ttgacaacta atgatcttat tggcaaatca gtctcagcca gcattgtaga
      601 aagtgctgcc gaaactagta agattgctca atttcaaacg aagattgtac gtgtaatcaa
      661 tgatgaagat gacatggagg acagcaacag tttcatgctg tctcatcaaa tggaaacgat
      721 tttgaaagag gctggattta cgaaagctgt atcttatttt atcttggaac tcaaagatcc
      781 atcacagaca aaagtagtaa cagaagaatt acagaaaaat aagaagtata ctgtgctttc
      841 tcaacagaga gttcttgata ttgtgattac ctttattcgt gttattcagg gattattgat
      901 tgtgctttca tcacaagcta ttgtggtagc agcggttatg attggtatca ttatttacat
      961 caatatcatg caacgttcca aggaaatagg tgtcatgaaa gcagttggtt atcagaatcg
     1021 tggtgtcaaa ggaattttta tttacgaggc tatctggatt gtaggcatcg ccttgctgct
     1081 ggcatttttg gttgcacaag gggtgggaag tttggcgaat gcgattgtaa gtcactttta
     1141 cccatccatc actaaggttt ttgaattaaa tcttttatct gttttaggaa ctctagtttt
     1201 cgctctatta cttggttatg tctcagccta cttcccggcg cgtaagatta gtaaaatgga
     1261 tcctgtagaa tcgttacgct atgaataata agggattcct tgatttacag tcttaaaaag
     1321 aaactcacat agaaaaacaa tggccatact tgcaattcaa ctcaaatagt tgtataatag
     1381 gtttgttgaa aggtgatttg tagtgattca agttactctt ttcacaataa aaatttcatg
     1441 attttcataa ggaggaaatc actaatggta gttaaagttg gtattaacgg tttcggacgt
     1501 atcggtcgtc ttgctttccg tcgtatccaa aacgtagaag gtgttgaagt tacacgcatc
     1561 aacgacctta cagatccagt tatgcttgca cacttgttga aatacgacac aactcaaggt
     1621 cgtttcgacg gtactgttga agttaaagaa ggtggattcg aagttaacgg taaattcgtt
     1681 aaagtttctg ctgaacgtga tccagagcaa atcgactggg ctactgacgg tgtagaaatc
     1741 gttcttgaag ctactggttt ctttgctaag aaagaagcag ctgaaaaaca ccttaaaggt
     1801 ggagctaaaa aagttgttat cactgctcct ggtggaaacg acgttaaaac agttgtattc
     1861 aacactaacc acgacgttct tgacggtact gaaacagtta tctcaggtgc ttcatgtact
     1921 acaaactgct tggctccaat ggctaaagct cttcaagata actttggtgt tgttgaagga
     1981 ttgatgacta ctatccacgc ttacactggt gaccaaatga tccttgacgg accacaccgt
     2041 ggtggtgacc ttcgccgtgc tcgcgctggt gctgcaaaca tcgttcctaa ctcaactggt
     2101 gctgcaaaag ctatcggtct tgtaatccca gaattgaatg gtaaacttga tggatctgca
     2161 caacgcgttc caactccaac tggatcagtt actgaattgg tagcagttct tgaaaagaac
     2221 gttactgttg atgaagtgaa cgcagctatg aaagcagctt caaacgaatc atacggttac
     2281 acagaagatc caatcgtatc ttcagatatc gtaggtatgt cttacggttc attgtttgac
     2341 gcaactcaaa ctaaagttct tgacgttgac ggtaaacaat tggttaaagt tgtatcatgg
     2401 tacgacaacg aaatgtcata cactgcacaa cttgttcgta ctcttgaata cttcgcaaag
     2461 attgctaaat aattcttgag ttgatagaaa gcaaggcttt gtggtcttgc ttttttatat
     2521 ggaaaaatgg atgacacgat catccattct tttttaattc tttttcaaat gtatttgaaa
     2581 gggtagtgaa agttagcctc tctaaagtaa gtgggtgggt aaaggaaagt cggaaggcat
     2641 gaagcataag ccggcttgtc tttgatttac tattatagag agggtctccc aggataggaa
     2701 gattatgatg caaaaggtgc acacgaatct gatgggttcg ccctgtcttt agcttgcaat
     2761 gagccaagga agtcttgttt gagaattgct ttaatctgct tacatgcgtt tcagcatatt
     2821 tcccattttt tgcatcaact attctttttc tacgatcatg gcgatcacgt ccaattttgt
     2881 ctctgaaaac aagttctttt ctgttgatat ttccatcaac tagagcccaa tattctctag
     2941 aaatctcttt tttctccaat aagcgattga gaatgggcag gataaaagga tttttggcaa
     3001 agagaactaa gccactggtt tccatgtcca gacgatgaac gacatagcag gtttggccaa
     3061 cataggtact gacatggtta agaagggcaa tttcgtttgg ttgattacca tgcgttttca
     3121 tcccctctgg tttgtttaca ataatcaagt gttgatcttg ataaacttcc tgcactaagt
     3181 ctgggttgcc ccaagggatc gtcttttggg gataatcttc ctcgtcaaaa gtcaactggc
     3241 aaacatctcc aggatttacg atttcgttcc agcggacttc ttcttgattt atcaaaatat
     3301 gtttcttgat tctcaaaaaa tgacggattt ttctagggat gaggagttgt tcctcaagta
     3361 attgctttac cgt
//
LOCUS       DAVHTH010000103         3353 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.104, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000103 DAVHTH010000000
VERSION     DAVHTH010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3353)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3353)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3353
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.104"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            complement(77..289)
                     /locus_tag="VVR63_002043"
     CDS             complement(77..289)
                     /locus_tag="VVR63_002043"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6130007.1"
                     /translation="MKIKEQTRKLAAGSSKHCFKVVDGTDEVSSKHCFKVVDGTDEVS
                     SKHCFEVVDRTDEVSNHIRQGDVDVV"
     gene            complement(339..971)
                     /locus_tag="VVR63_002044"
     CDS             complement(339..971)
                     /locus_tag="VVR63_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEU6130008.1"
                     /translation="MTSITAIFFDLDGTLVDSSIGIHNAFTYTFKELGVPSPDAKTIR
                     GFMGPPLESSFATCLSKDQISEAVQIYRSYYKAKGIYEAQLFPQIIDLLEELSSSYPL
                     YITTTKDTSTAQDMAKNLEIHHFFDGIYGSSPEAPHKADVIHQALQTHQLAPEQAIII
                     GDTKFDMLGARETGIQKLAITWGFGEQADLLNYQPDYIAHKPLEVLAYFQ"
     gene            complement(993..1865)
                     /gene="sdaAA"
                     /locus_tag="VVR63_002045"
     CDS             complement(993..1865)
                     /gene="sdaAA"
                     /locus_tag="VVR63_002045"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HEU6130009.1"
                     /translation="MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLME
                     RNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIENGKTLSDYTILSAARNAIAVNE
                     HNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASI
                     SGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEV
                     PCVKRNAMGASFAFIAADMALAGIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLAT
                     TPTGRRLQKEIFGE"
     gene            complement(1874..2545)
                     /gene="sdaAB"
                     /locus_tag="VVR63_002046"
     CDS             complement(1874..2545)
                     /gene="sdaAB"
                     /locus_tag="VVR63_002046"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HEU6130010.1"
                     /translation="MKSLRFQSVFDIIGPVMIGPSSSHTAGAVRIGKIVSSIFDDTPT
                     EVEFQLFNSFAKTYRGHGTDLALVAGILGMDTDDPEIPNSLEIAHKRGIKIVWTIQKD
                     SNAPHPNTTKITVKNAHKTISVTGISIGGGNIQVTELNGFAVSLNMNTPTIIIVHQDI
                     PGMIALVTEALSRYGINIAQMNVTREKAGEKAIMIIEVDSRNCDEAIEEIRKIPHLHN
                     VNFFK"
     gene            2787..>3353
                     /locus_tag="VVR63_002047"
     CDS             2787..>3353
                     /locus_tag="VVR63_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEU6130011.1"
                     /translation="MKSITKKIKATLAGVAALFAVFAPSFVSAQESSTYTVKEGDTLS
                     EIAETHNTTVEKLAENNHIDNIHLIYVDQELVIDGPVAPVATPAPATYAAPAAQDETV
                     SAPVAETPVVSETVVSTVSGSEAEAKEWIAQKESGGSYTATNGRYIGRYQLTDSYLNG
                     DYSAENQERVADAYVAGRYGSWTAAKNFW"
BASE COUNT          976 a          697 c          721 g          959 t
ORIGIN      
        1 acgcatagta tcaagttaca caaccttggt aatatgcgtt ttattatgta gagacttata
       61 ctcttcgaaa atctcttcaa accacgtcaa cgtcgccttg ccgtatatgg ttactgactt
      121 cgtcagttct atccacaacc tcaaaacagt gttttgagct gacttcgtca gttccatcca
      181 caaccttaaa acagtgtttt gagctgactt cgtcagttcc atctacaacc ttaaaacagt
      241 gttttgagct gcccgcagct agtttcctag tttgctcttt gattttcatt gagtattact
      301 tcattttctt ctgaaatgga attgttaccc agtctatgct attgaaaata cgccaaaact
      361 tctaagggtt tgtgagcgat ataatcaggt tgatagttta gtagatctgc ttgctctcca
      421 aatccccaag tgatggccaa tttctgaata cctgtttctc gagctcccag catatcaaac
      481 ttggtatctc cgatgatgat ggcttgttct ggtgctagtt gatgtgtctg caaggcttgg
      541 tgaatgacat ctgccttatg gggtgcttca gggctagaac cataaatgcc atcaaagaaa
      601 tgatggattt ccaagttttt tgccatgtct tgagcagtag atgtatcctt tgtcgtggtg
      661 atgtagagtg gataactgct cgataactcc tcaagcaagt ctataatctg aggaaagagt
      721 tgagcttcat agatgccttt tgccttatag taagaacgat atatctgcac ggcttcagaa
      781 atttggtctt tggacaggca ggtcgcaaaa ctactttcga gaggtggtcc cataaaacca
      841 cgaatagttt tggcatcagg gctaggcacc cccagctctt taaaggtata ggtaaaggca
      901 ttgtgaatcc cgatagaact atcaacgagg gttccatcca aatcgaaaaa aatcgctgtg
      961 atagaggtca tggtttctcc tatttgataa gcttattctc cgaaaatttc tttttggagg
     1021 cgacgaccag taggggtggt agcgagtcca ccttcagctg tttcacgaaa ggcagttggc
     1081 atgcttgctc ctacttggta catggcatcg atcacttcat ccacagggat tttagattcg
     1141 atacctgcca aggccatgtc tgctgcgatg aaagcaaagc tagctcccat ggcattacgt
     1201 ttgacacagg gaacttcgac caaacctgca acagggtcac agatgaggcc tagcatattt
     1261 ttaatgacaa aggcaatagc ttgactggcc tgataaggtg ttccacctgc agccagagtc
     1321 aaggcggcag cactcatagc agaggctgaa ccaacttcag cttgacaccc accctcagca
     1381 cctgagatgg aggcattgtt tgcgatgact agtccaaagg caccagcagc aaagaggaaa
     1441 tccaattgtt gctcgtggct gaggtctaat ttttcaatag cagcagtgag aacggatggc
     1501 agacagccag cacttccagc ggttggagtg gcacagacca agcccatttt ggcattgtgt
     1561 tcattgactg cgatggcatt tcgggcagcc gagagaatcg tataatctga cagagttttt
     1621 ccgttttcga tgtagtgatc caatttggca gcatctccac ctgtcaggcc actacgagat
     1681 ttattttcat tgaggccaag ttggacagag gctttcataa cttccagatt gcgttccatg
     1741 agaaggaaga cttcttcacg ttcgcgaccg gtcaattcaa actctgttgt aatcatgagt
     1801 tctgcgacat ttccttgaaa gtccagatct gcttgctcga ccaattcttt gatagaataa
     1861 aacatgcttc ctcctattta aagaaattga cattgtggag atgagggatt tttcgaattt
     1921 cttcgatagc ctcatcacag ttgcgactgt caacttcgat aatcataatg gctttttcac
     1981 cagctttttc acgagtgaca ttcatctggg cgatattgat accatagcgg gaaagcgcct
     2041 ctgtaacaag ggcaatcata cctggaatat cttgatgaac gatgatgata gtcggtgtat
     2101 tcatattgag agagacggca aaaccattga gttcggttac ctgaatattt cctccaccga
     2161 tagaaatacc agtcacgctg atggtcttgt gggcattttt aacagtaatt ttagtggtgt
     2221 tagggtgagg ggcattgctg tctttctgaa tggtccagac aatcttgata ccacgcttgt
     2281 gggcaatttc cagactattt ggaatttcag gatcatctgt atccattcct aaaatacctg
     2341 caacaagggc taggtctgtt ccgtgaccac gataggtctt ggcaaatgag ttaaaaagtt
     2401 ggaattcaac ttctgtcgga gtatcatcaa aaatggaaga gacaatcttc ccaatacgaa
     2461 cagcaccagc ggtatggcta ctagatgggc caatcataac tggtccgatg atatcaaaga
     2521 cagattgaaa acgaagtgat ttcatcagtt tccccttata aaaattctta tctctattat
     2581 atcaaagaat gaggggcttg gctttaattg tggatgaaaa cctttctaat acctcaaata
     2641 gcataaaaat agtatctttt atgacaaaaa acaccttatt tagggaaata aaaaataatt
     2701 ttgtaatatt tctacataaa agtgtcaaga aacggtaata tttaaagggt atgatagaac
     2761 tatagaaaga aggagaattt tcgaatatga aatcaataac taaaaagatt aaagcaactc
     2821 ttgcaggagt agctgccttg tttgcagtat ttgctccatc atttgtatct gctcaagaat
     2881 catcaactta cactgttaaa gaaggtgata cactttcaga aatcgctgaa actcacaaca
     2941 caacagttga aaaattggca gaaaacaacc acattgataa cattcatttg atttatgttg
     3001 atcaagagtt ggttatcgat ggccctgtag cgcctgttgc aacaccagcg ccagctactt
     3061 atgcggcacc agccgctcaa gatgaaactg tttcagctcc agtagcagaa actccagtag
     3121 taagtgaaac agttgtttca actgtaagcg gatctgaagc agaagccaaa gaatggatcg
     3181 ctcaaaaaga atcaggtggt agctatacag ctacaaatgg acgttatatc ggacgttacc
     3241 aattaacaga ttcatacctg aacggtgact actcagctga aaaccaagaa cgtgtagcag
     3301 atgcctacgt tgcaggacgt tacggttcat ggactgctgc taaaaacttc tgg
//
LOCUS       DAVHTH010000104         3338 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.105, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000104 DAVHTH010000000
VERSION     DAVHTH010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3338)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3338)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3338
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.105"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            273..1178
                     /locus_tag="VVR63_002048"
     CDS             273..1178
                     /locus_tag="VVR63_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HEU6130012.1"
                     /translation="MTAFQQLPSSVLQTGAIFLSIIIEALPFVLIGSIVSGLIEVYIT
                     PDKVYHFLPRNRWGRIFFGTFVGILFPSCECGIVPIINRFLEKKVPSYTAVPFLVTAP
                     VINPIVLFATYSAFGNSFHVALLRALGSILVAVILGIFLGFFWQEPIQKENRLACHEH
                     DFSYLSSAKKVFQVFVQAIDEFFDTGRYLVFGCLFASIIQVYVPTRILTSISATPLFA
                     ILLLMLLAFLLSLCSEADAFIGASLLSSFGLAPVLAFLVIGPMLDIKNILMMKNYLKA
                     RFISHFITIVTLVVLAYSLLIGVIL"
     gene            1175..1990
                     /locus_tag="VVR63_002049"
     CDS             1175..1990
                     /locus_tag="VVR63_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HEU6130013.1"
                     /translation="MIRFLVLAGYFELTIYLHLSGKLNQYINMHYSYLAYISMVLSFI
                     LAIVQLYIWMKQVKTHSHLNSRLAKMTSISLLAIPLIIGLTFPTVSLDSQTVSAKGYH
                     FPLSEGTDLAIQTSEGTTSQYLKPDTSSYFSKSAYEKEMRTAADKYLSQDSIQITNEN
                     YMEVMEAIYDYPDEFEGKTIQFTGFVYNDPSHANSQFLFRFGIIHCIADSGVYGLLTK
                     GNTRQYENNTWISAKGKLVNHYHKELKQNLPTLEIDSFTKVDKPENPYVYRAF"
     gene            complement(2120..2836)
                     /locus_tag="VVR63_002050"
     CDS             complement(2120..2836)
                     /locus_tag="VVR63_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEU6130014.1"
                     /translation="MKKYFISGLGSNAYHSKDFFQELDSQVYFLNPYEKHLRDETELK
                     SWFKNEIVEEESICLIGHSLGGDLARYSASEFEEVKKLILLDGGYLDLDKILPLDTEL
                     EETKNYIKSQIVSDLALLTSKEKSEAKHWSENMEKAVRQSYHWNVEYNRYELAINYEN
                     IEAIFRLRRKIQAFKREVGDTLFISPRYPNEATWREEALKELPDYFDTIFLENFGHEL
                     YTQAPKEIASLMNEWLAYFL"
     gene            complement(2840..3151)
                     /locus_tag="VVR63_002051"
     CDS             complement(2840..3151)
                     /locus_tag="VVR63_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6130015.1"
                     /translation="MELKDFTEKEQEMIKKRLTMSNISDKETTEKILALVPQDLIKRI
                     PFFVRKHATTRTIKRISIEHPELYAVAQTSGEIPEKEREELRQIITTIFEQKMNKHSI
                     K"
BASE COUNT          964 a          690 c          573 g         1111 t
ORIGIN      
        1 aaccgtacta cggtaaggcg aagctgacgt ggtttgaaga gattttcgaa gagtatcaac
       61 tatcgaaaac aaattaaaaa actccctttt ccgcaaaata atagtataat agaggtagaa
      121 tttagaatcg aggtacacct atggctgtca aatttacaaa acgagacgac ttggacaaga
      181 tgtttgaaga gtttgctaaa ctccctgatt tgaaacaagt tactttccct gatgacaaag
      241 agaaaaaagt caaagcagaa aagaaaaact agatgactgc ttttcaacaa ctcccatcta
      301 gtgtacttca aactggagcc atttttctct ccattatcat tgaagccctt cccttcgttc
      361 tgataggaag cattgtctca gggctgattg aagtttatat cacacctgac aaggtttatc
      421 attttctccc tcgaaatcgt tgggggagaa tcttttttgg gacctttgtc ggtatacttt
      481 tcccttcttg tgaatgtgga atcgtcccca tcatcaatcg ttttctggaa aaaaaggttc
      541 caagttacac ggccgttcct tttcttgtga cagcacctgt tatcaatccc attgttcttt
      601 ttgcgaccta ttctgccttt ggcaactcct tccatgtcgc cctattacga gctctgggtt
      661 ccattcttgt ggctgtaata ctaggaattt ttctaggatt tttctggcaa gaaccgattc
      721 agaaagaaaa tcgtctggct tgtcatgagc atgatttttc ttacttgagt tctgcaaaaa
      781 aagtttttca agtctttgtg caggccattg atgaattttt tgatacgggg cgttatttgg
      841 tatttggctg cctctttgct tctataatac aggtctacgt tccgactcgg attctgacct
      901 ctatcagtgc gactcctctt tttgccatcc tgctcttgat gcttttggcc tttcttcttt
      961 cgctttgtag tgaggcggat gcctttatag gtgcttctct actctcgagt ttcggtttgg
     1021 ctccagttct ggcctttctc gtcattggcc caatgctgga tatcaaaaat attctcatga
     1081 tgaaaaatta cttgaaagca cgatttatta gtcacttcat tacgattgtg actctggtcg
     1141 ttttagccta ttctctcttg attggagtca tcctatgatt cgatttttag ttttagctgg
     1201 ctattttgaa ctgactattt acctccatct gtcgggcaaa ctaaaccagt acatcaacat
     1261 gcactattcc tatctggcct atatctccat ggtgctttcc tttatcttgg caattgttca
     1321 attgtatatc tggatgaagc aagtcaaaac ccacagtcat ctgaacagcc gattggccaa
     1381 gatgacgagt atttctcttc tggctattcc acttatcatc ggcttaactt tcccaactgt
     1441 tagcttggat tctcagaccg tttctgctaa aggttatcat ttccccctat cagaaggaac
     1501 ggatctagcc attcagacaa gcgaagggac gacaagccaa tatttgaaac cagataccag
     1561 ttcttatttt tcaaaatcag cctatgaaaa ggaaatgcga acggcggcgg ataaatactt
     1621 atcccaagat agtattcaga tcactaatga aaactatatg gaagtcatgg aggctatcta
     1681 cgactatcca gatgagtttg agggcaagac aatccagttt acaggctttg tctataacga
     1741 ccccagtcat gccaatagtc aatttctgtt ccgattcggc attatccact gtatcgcaga
     1801 ttctggtgtc tatggattgc tgaccaaggg caatacccgg cagtatgaaa acaacacttg
     1861 gatttcagcc aaaggaaaac tggtcaatca ctaccataaa gaactcaaac aaaaccttcc
     1921 aaccttggaa atcgacagct ttaccaaagt cgataaacca gaaaatccct atgtatatag
     1981 agctttttaa gaaaatcaag ataaaaacga acaagttctc ttctgaataa cagaaaaaga
     2041 gcctgttcgt tttttggtta tatgaaaatt agtgacttgt agattttcat cttataccat
     2101 ttccagcaat acaagtagct catagaaaat aagcgagcca ctcattcatt agactagcga
     2161 tttctttagg tgcttgagta taaagctcat ggccaaagtt ttctaaaaaa atagtatcaa
     2221 aatagtctgg caattctttt agggcttcct ctctccatgt agcttcatta ggatagcgag
     2281 gactaataaa caaggtatct cccacttctc tcttaaaagc ttgtattttt ctccgtaggc
     2341 ggaatatcgc ttctatattt tcataattta tagccaactc atatctatta tactcaacat
     2401 tccagtgata ggactgtctt acagctttct ccatattttc tgaccaatgc tttgcttcag
     2461 atttttcttt agaagtaaga agagctaagt ccgaaacaat ttgagatttg atataatttt
     2521 tagtttcctc taactctgta tccaaaggta aaatcttatc taaatctaga tagccaccat
     2581 ccaaaagaat cagtttcttt acttcttcaa attccgatgc ggaataacga gctaaatctc
     2641 ctccaagaga atgacctatc agacagatag attcttcctc tacaatctca tttttaaacc
     2701 atgatttcaa ttctgtttca tctcgaagat gcttttcata tggatttaga aaatagacct
     2761 gcgaatctag ttcttgaaaa aaatccttgc tatgataggc attgcttccc aaaccgctaa
     2821 taaaatattt tttcattctc tacttaatac tatgcttatt catcttttgt tcaaagatag
     2881 tcgtgataat ctgacgcaat tcttcgcgtt ctttttccgg aatctcacca cttgtttgag
     2941 ctacagcgta gagttcaggg tgttcaattg aaatgcgttt aatcgtacgt gttgtagcat
     3001 gttttctgac aaaaaacggg attcgcttaa tcaagtcttg tggtactagc gccagaatct
     3061 tctcagtagt ttctttgtca ctaatattag acattgtaag ccttttctta atcatttcct
     3121 gttctttttc tgtaaaatct tttaattcca ttcgattagt cctcctattt tctctaagtt
     3181 aaattatgta ctaatacaga tgaaactaca aagaataaac tttaagaaat cttctcactg
     3241 ataagatttt agcattagac ttcctgcgaa acaaaatatg gtatagtagt tctatgaatt
     3301 atgaagcaag taaacaacta actgatgcac gatttaaa
//
LOCUS       DAVHTH010000105         3292 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.106, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000105 DAVHTH010000000
VERSION     DAVHTH010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3292)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3292)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3292
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.106"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            97..2292
                     /locus_tag="VVR63_002052"
     CDS             97..2292
                     /locus_tag="VVR63_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEU6130016.1"
                     /translation="MKLDKLFEKFLSLFKKETSELEDSDSTILRRSRSDRKKLAQVGP
                     IRKFWRRYHLTKIILILGLSAGLLVGIYLFAVAKSTNVNDLQNALKTRTLIFDREEKE
                     AGALSGQKGTYVELTDISKNLQNAVIATEDRSFYKNDGINYGRFFLAIVTAGRSGGGS
                     TITQQLAKNAYLSQDQTVERKAKEFFLALELSKKYSKEQILTMYLNNAYFGNGVWGVE
                     DASKKYFGVSASEVSLDQAATLAGMLKGPELYNPLNSVEDSTNRRDTVLKNMVAAGYI
                     DKNQETEAAEVDMTSQLHDKYEGKISDYRYPSYFDAVVNEAVSKYNLTEEEIVNNGYR
                     IYTELDQNYQANMQIVYENTSLFPRAEDGTFAQSGSVALEPKTGGVRGVVGQVADNDK
                     TGFRNFNYATQSKRSPGSTIKPLVVYTPAVEAGWALNKQLDNHTMQYNSYKVDNYAGI
                     KTSREVPMYQALAESLNLPAVATVNDLGVDKAFEAGEKFGLNMEKVDRVLGVALGSGV
                     ETNPLQMAQAYAAFANEGLMPEAHFISRIENASGQVIASHKNSQKRVIDKSVADKMTS
                     MMLGTFTNGTGISSSPADYIMAGKTGTTEAVFNPEYTSDQWVIGYTPDVVISHWLGFP
                     TTDENHYLAGSTSNGAAHVFRNIANTILPYTPGSTFTVENAYKQNGIAPANTKRQVQT
                     NDNSQTDDNLSDIRGRAQSLVDEASRAISDAKIKEKAQTIWDSIVNLFR"
     gene            2345..2497
                     /gene="rpmG"
                     /locus_tag="VVR63_002053"
     CDS             2345..2497
                     /gene="rpmG"
                     /locus_tag="VVR63_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEU6130017.1"
                     /translation="MALKKASLACAVCGSRNYSIKISGNPKPTRLEVNKFCKHCGKYT
                     THRETR"
     gene            2507..2683
                     /gene="secE"
                     /locus_tag="VVR63_002054"
     CDS             2507..2683
                     /gene="secE"
                     /locus_tag="VVR63_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HEU6130018.1"
                     /translation="MRFIGDIFRLLKDTTWPTRKESWRDFRSIMEYTAFFVVIIYIFD
                     QLIVSGLIRFINIF"
     gene            2738..3274
                     /gene="nusG"
                     /locus_tag="VVR63_002055"
     CDS             2738..3274
                     /gene="nusG"
                     /locus_tag="VVR63_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000376740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HEU6130019.1"
                     /translation="MDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEIP
                     TQTVQVEKNGKRKEVEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKPT
                     PLLEQEIRDILVSMGQTVQEFDFDVEIGQTVRIIDGAFADYTGKITEIDNNKVKMIIS
                     MFGNDTVAEVNLNQIAEL"
BASE COUNT         1067 a          566 c          726 g          933 t
ORIGIN      
        1 tgaattgcat acagatattg taacaaaaaa agccctattt ggataggaaa tagctaaatt
       61 cttgtcttcc tatgatgaag atgataaaat aaacgcatga aattagataa attatttgag
      121 aaatttcttt ctctttttaa aaaagaaaca agtgaactag aggactctga ttctactatc
      181 ttacgtcgct ctcgtagtga tcgaaaaaaa ttagcccaag taggtccgat tcgaaaattc
      241 tggcgtcgtt atcatctaac aaagattatc cttatactag gtttgagtgc aggcttgcta
      301 gttggaatct atttgtttgc tgtagccaag tcgaccaatg tcaatgattt gcaaaatgcc
      361 ttgaaaactc ggactcttat ttttgaccgt gaagaaaaag aggctggtgc cttgtctggt
      421 caaaagggaa cctatgttga gctgactgac atcagtaaaa acttgcagaa tgctgttatt
      481 gcgacagaag accgttcttt ctataaaaat gacgggatta actatggccg tttcttcttg
      541 gctattgtca ctgctggacg ttcaggtggt ggctctacca ttacccaaca gctggctaaa
      601 aacgcctatt tatcgcagga tcaaactgtt gagagaaaag cgaaagaatt tttccttgcc
      661 ttagaattaa gcaaaaaata tagtaaggag caaattctaa ccatgtacct taacaacgct
      721 tattttggaa atggtgtgtg gggtgtagaa gatgcgagta agaaatactt tggagtttct
      781 gcatcagaag tgagtctgga tcaagctgcg actctggcag ggatgctcaa ggggccggaa
      841 ctgtataatc ccttgaattc cgtagaagat tctactaatc ggcgcgatac tgtcttgaag
      901 aatatggttg cagcaggata tattgataaa aaccaagaaa ccgaagctgc tgaagttgat
      961 atgacttcgc aattgcacga taagtatgaa ggaaaaatct cagattaccg ttacccctct
     1021 tattttgatg cggtggttaa tgaagctgtt tccaagtata atctaacaga ggaagagatt
     1081 gtcaataatg gctaccgcat ttacacagag ctggaccaaa actaccaagc aaatatgcag
     1141 attgtttatg aaaacacatc gctatttccg agggcagagg atggaacgtt tgctcaatca
     1201 ggaagtgtag ctctcgaacc gaaaacaggg ggagttcgtg gagttgtcgg tcaagttgct
     1261 gacaatgata aaactggatt ccggaatttc aactatgcaa cccaatcaaa gcgtagtcct
     1321 ggttctacaa ttaagccttt agttgtttat acgccagcag ttgaagcagg ctgggctttg
     1381 aataagcagt tggataacca taccatgcag tataacagct ataaggttga taactatgca
     1441 gggatcaaaa cgagtcgaga agttcctatg tatcaagcct tggcagaatc gcttaatcta
     1501 cctgctgttg ccactgttaa tgatttgggt gttgacaagg cttttgaggc aggcgaaaaa
     1561 ttcggactca acatggaaaa ggtcgaccgt gttcttggtg tcgccttggg aagcggtgtt
     1621 gaaaccaacc ctcttcaaat ggctcaagca tacgctgcct ttgcaaatga aggtttaatg
     1681 cctgaagctc attttattag tagaattgaa aatgctagtg gacaagttat tgcgagtcat
     1741 aaaaattcac aaaaacgggt gattgataag tctgtagctg acaagatgac cagtatgatg
     1801 ttggggactt tcaccaacgg taccggtatt agttcatcgc ctgcagacta tattatggca
     1861 gggaaaactg gaacaactga agcagttttc aatccggagt acacaagtga ccagtgggta
     1921 attggttata ctccggatgt agtgattagc cactggcttg gctttcctac cactgatgaa
     1981 aatcactatc tagctggctc tacttcaaac ggtgcagctc atgtctttag aaacattgcc
     2041 aataccattt taccttatac gccaggaagt acctttacgg ttgaaaatgc ttataagcaa
     2101 aatggaattg caccagccaa tacaaaaaga caagtacaaa ccaatgataa tagccagaca
     2161 gatgataatt tgtctgatat tcgagggcgt gcgcaaagtc tagtagatga ggctagccgg
     2221 gctatctcag atgcgaagat taaggaaaag gctcaaacaa tatgggattc gatagtcaat
     2281 ctatttcgtt aagatgcttg tcaaagccta gctttcttgt tataatggat aagatggagg
     2341 cgttatggca ctaaaaaaag caagcctagc ttgtgcggtt tgtggttcga gaaactattc
     2401 aatcaagatc agcggaaacc ccaagcctac acgactagaa gtaaataaat tttgtaagca
     2461 ttgtggcaag tacactacac acagagaaac gagataggag agagcgatgc gttttattgg
     2521 agatattttt agacttctta aagacacaac atggccaact cgcaaggaaa gctggagaga
     2581 ttttcgttct atcatggaat acacagcttt ctttgtagta attatttaca tttttgacca
     2641 gttgattgtt tcaggtttga ttcgatttat taacattttt tagaagatta gtggagttaa
     2701 ttacactaga aatcttctat ttatgaaagg aaatatcatg gatagttttg ataaaggatg
     2761 gtttgtttta caaacttatt ctggttatga aaataaggtg aaagaaaatc tattacaacg
     2821 tgcacaaacc tacaatatgt tggataatat tctacgcgtt gaaattccaa cacaaacagt
     2881 gcaagttgaa aaaaatggaa agagaaaaga agtagaagaa aatcgctttc caggttatgt
     2941 tcttgtagaa atggtcatga cagatgaagc ttggtttgtt gttcgaaaca caccaaatgt
     3001 tacaggattt gtcggatcac acgggaacag atcaaaacca actccattat tggaacaaga
     3061 aattcgtgac attttggtat ctatgggaca aactgttcaa gaatttgatt tcgatgttga
     3121 gattggtcaa actgtacgta ttattgatgg tgcttttgca gactacactg gtaagattac
     3181 agaaattgat aataacaaag tgaaaatgat tatctctatg tttggtaatg acacagttgc
     3241 agaagtaaac ctaaaccaaa tcgcagaatt ataaccctga gagaggctgg ag
//
LOCUS       DAVHTH010000106         3292 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.107, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000106 DAVHTH010000000
VERSION     DAVHTH010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3292)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3292)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3292
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.107"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            complement(<1..1553)
                     /locus_tag="VVR63_002056"
     CDS             complement(<1..1553)
                     /locus_tag="VVR63_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU6130020.1"
                     /translation="MTRKVPNIEQMSQIECGLCCCLSILHFYKSKETLLDLRRDIEKG
                     RDGYSIGDLKQLLNKRNFDTGSYQVKDVNKISELPLPLIAFWDNQHYVVIYKVKKNKV
                     YIMDPSKGYINYEFKEFSKHFSNIVLLSFPNENYQSLKSQFPSPWIRVFSSFSKVKGR
                     LILTLLFSIISYLIILSVPVMTSKFINSALGNTFSFQTSFLILFSLLCLYLISILARS
                     MGILFSNIFFSRDIESFTFKHLLKLPYSFFELRAKGDILYRISSLSGFRELFTNQVVG
                     GVVDIGTILSVVIYMFLSSKTLSIIALILSLINFLFLFSTRKIMYDTVNRELQEQSLI
                     YSVETEALNTISSIKISGLEDEIYENWSKYLKNVLTKYKKRSIVHILYNSATNVFQLF
                     APIIILIFGLDNVLNGKILLGEVVAFQTMASILFSSEISIFNAYTQYILAAGYLNRVN
                     DIWLENEENVENGLKKCSLEGRIDIKDLSFSYSKDSAPVIENLNLTIEPGQRIALVGQ
                     SGSGKSTLS"
     gene            complement(1546..2094)
                     /locus_tag="VVR63_002057"
     CDS             complement(1546..2094)
                     /locus_tag="VVR63_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000059560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6130021.1"
                     /translation="MSLSYYYEINPSTDILKCIEELLYKEDKCFNNILKNWKDIRRNH
                     NDSFPNFWCYGAPGILLARKEIFDKTNIGNNDLSIIKNVLTNVEKIRELNLCHGSVGT
                     ISCLDAILKDEENLLIKESIDFYFDNVVSQVIKPELSTDLNTMNTFSFMLGVSGVVYE
                     ISRKQDDRLLNVLLLELRGHDD"
     gene            complement(2175..2237)
                     /locus_tag="VVR63_002058"
     CDS             complement(2175..2237)
                     /locus_tag="VVR63_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_128650800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHP2/SHP3 family peptide pheromone"
                     /protein_id="HEU6130022.1"
                     /translation="MKKISKFLPILVLVMDIIII"
     gene            2317..3168
                     /locus_tag="VVR63_002059"
     CDS             2317..3168
                     /locus_tag="VVR63_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016182753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator"
                     /protein_id="HEU6130023.1"
                     /translation="MKSKLGITLRKVRKGKQISLCSVADEHLSKSQISRFERGESEIS
                     CIRLINILDKLHITLDEFLVLHNDDYTSSESFANLVQYIRKQYSSQSINNIACLLSDT
                     SDYTLNSFEKTMVKSILHTMDSNIIPSDEELLHLTDYLFKIEKWGYYEIILLGNCVRT
                     INYNSYFLLTKEMLNNYIYSSLNKTNKQIVSQLAINCFILSIDKEEFSNCSYLISKIK
                     TLLDNELNFYEQTVFLYATGYYEFKRQLSSGIETMKQAIQVLDILGEDKLKLHYTSHF
                     DKLVNNK"
BASE COUNT         1187 a          536 c          397 g         1172 t
ORIGIN      
        1 tttgataacg tactttttcc tgaccccgat tgaccgacta gtgcaattct ctgtcctggc
       61 tcaatagtca aatttaaatt ttctattaca ggagctgagt ctttggaata agagaaagat
      121 aggtccttaa tatctattct accttctaaa gaacactttt taagaccatt ttcaacattc
      181 tcttcatttt caagccagat atcatttact ctatttaagt atcctgctgc caaaatatac
      241 tgcgtataag cattaaatat tgagatttct gaactaaata aaattgatgc catggtttga
      301 aatgcgacaa cctcacccaa taaaattttt ccatttaaaa cattatcaag tccaaaaatc
      361 aatataatta taggagcgaa caattgaaat acattagtag ctgaattgta taaaatatgc
      421 acaatacttc gttttttata ctttgtcaat acgtttttta aatacttaga ccagttttca
      481 tatatttcat cttctaatcc cgatattttt attgaagaaa tagtatttaa tgcttctgtt
      541 tctactgagt aaatcaatga ttgttcttgt aattctctat taaccgtatc atacattatt
      601 tttctagtac taaacagaaa caaaaaattg attaaactca atataagagc tataattgat
      661 aatgtttttg aactaagaaa catatatatt acaacactta gaatagtccc gatatctact
      721 actcccccaa caacttggtt agtaaatagc tccctaaaac cactaagact agaaattctg
      781 tataaaatat ctccttttgc cctgagttca aaaaaactat atggtagttt aagcaaatgc
      841 ttaaatgtaa aactttcaat atctctacta aaaaatatat tagaaaatag aattcccata
      901 ctcctagcca agatagaaat aagatacaaa caaagtagag aaaataaaat taaaaacgag
      961 gtttgaaaag aaaatgtatt ccctaatgca gaattaataa actttgaagt cattactggt
     1021 acggaaagta ttattaagta acttattatt gaaaatagta acgtcaaaat caatcgacct
     1081 tttacctttg aaaaactaga gaatactctt atccatggag aaggaaactg cgacttcaaa
     1141 gattgataat tttcgttagg aaatgatagc agtactatat tactaaaatg ttttgaaaac
     1201 tccttaaact cataatttat atatccttta gaaggatcca ttatatagac cttattcttt
     1261 tttactttgt aaataactac ataatgttga ttatcccaga atgctattaa tggtaacgga
     1321 agttcactaa ttttatttac atctttaact tgatatgagc cagtatcaaa atttcgttta
     1381 ttcaataact gtttcaagtc acctatacta taaccatctc tccctttttc tatatcacgt
     1441 cttaaatcta gtaatgtctc tttgctttta tagaaatgta gtatggacaa gcagcaacat
     1501 aaaccacatt ctatttgaga catttgctca atattaggta cttttctagt catcatgtcc
     1561 tcttaactcc agtaataaaa cattaagtaa tctatcatct tgttttcgag atatttcata
     1621 gacaactcca gatactccta gcataaaaga aaatgtattc atagtattca aatccgtact
     1681 taattctggt ttgatgacct gagaaacgac attatcaaaa taaaaatcta tagattcttt
     1741 tattaatagg ttttcttcat ctttcaatat tgcatcaaga caactgatag tacctacaga
     1801 accgtgacat aaattcaatt ctcttatttt ttctacatta gttaatacat ttttaattat
     1861 tgataaatca ttattcccaa tattagtttt atcgaaaatt tcttttctag ctaataaaat
     1921 gcccggagct ccataacacc aaaaattagg aaaggaatca ttatgatttc ttcttatgtc
     1981 tttccaattt tttaatatat tattgaaaca tttatcttct ttatatagta attcctctat
     2041 acattttaat atatctgtac taggattaat ttcataataa tatgataatg acattgctac
     2101 tccagaataa ccgtgtgcta aacctgttac tgttatatta tctaattgtg aaatacaata
     2161 attaatacac ttttttaaat gatgataata tccatcacca aaaccaaaat cggtaaaaat
     2221 tttgaaattt tcttcatact tggacttcct ttccgttttt atttattgta caataaataa
     2281 aaacggattt aatttttgtt gggaaaatgg gaaattatga aatcaaaact tggcatcaca
     2341 cttagaaaag ttcgtaaagg aaaacaaatt agtctatgct ctgtagcaga tgaacatctt
     2401 tcaaaatcac aaatatctcg ttttgaacgt ggggagtcag agatatcttg tattcgacta
     2461 atcaatattt tagacaaatt acatattact ttggatgagt tccttgtttt acacaatgac
     2521 gactatacca gttccgaatc atttgctaat ctagtacagt acattcgtaa gcaatattca
     2581 tcacaaagta tcaataatat agcatgtcta ctttctgata cttctgatta cactctaaat
     2641 tcttttgaga aaacaatggt aaaatctatt ttacacacaa tggattcgaa catcattcca
     2701 tcagatgaag agcttcttca tctgacagac tatcttttca aaattgaaaa atggggctat
     2761 tatgaaatca ttttattagg taactgtgta cgcacaatta actacaactc ctacttctta
     2821 ttaactaaag agatgttaaa taactatatt tactcatctc tgaataaaac taataagcag
     2881 attgtctctc agcttgctat taattgcttc attctaagca ttgataagga agaattttct
     2941 aattgctcct atttaattag taagataaag acattgttgg ataatgaact aaacttttat
     3001 gaacagacag tttttctcta tgcaaccggt tactatgaat ttaaacgtca attaagtagt
     3061 ggtattgaaa caatgaaaca agctatacaa gttctcgata ttttaggaga agacaagtta
     3121 aaattacact atactagcca ttttgataaa cttgtaaaca ataaatgaaa tgattctcta
     3181 tcttttaact aattagtcgt aaataatatt attctagtaa ggcattctcg tgaaatttta
     3241 gaactgtaaa tttattggta ttaataattt tcacaaacaa atccaatctt ct
//
LOCUS       DAVHTH010000107         3280 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.108, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000107 DAVHTH010000000
VERSION     DAVHTH010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3280)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3280)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3280
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.108"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            complement(189..800)
                     /gene="rpsD"
                     /locus_tag="VVR63_002060"
     CDS             complement(189..800)
                     /gene="rpsD"
                     /locus_tag="VVR63_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HEU6130024.1"
                     /translation="MSRYTGPSWKQARRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFTYGVGEKQFRNLFVQATKIKGGILGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVTPGQVISVREKSLKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            complement(995..2047)
                     /locus_tag="VVR63_002061"
     CDS             complement(995..2047)
                     /locus_tag="VVR63_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEU6130025.1"
                     /translation="MKLKSYILVGYIISTLLTILVVFWAVQKMLIAKGEIYFLLGMTI
                     VASLVGAGISLFLLLPVFTSLGKLKEHAKRVAAKDFPSNLEVQGPVEFQQLGQTFNEM
                     SHDLQVSFDSLEESEREKGLMIAQLSHDIKTPITSIQATVEGILDGIIKESEQAHYLA
                     TIGRQTERLNKLVEELNFLTLNTARNQVETTSKDSIFLDKLLIECMSEFQFLIEQERR
                     DVHLQVIPESARIEGDYAKLSRILVNLVDNAFKYSAPGTKLEVVAKLEKDQLSISVTD
                     EGQGIAPEDLENIFKRLYRVETSRNMKTGGHGLGLAIARELAHQLGGEITVSSQYGLG
                     STFTLVLNLSGSENKA"
     gene            complement(2044..2742)
                     /locus_tag="VVR63_002062"
     CDS             complement(2044..2742)
                     /locus_tag="VVR63_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU6130026.1"
                     /translation="MGKTILLVDDEVEITDIHQRYLIQAGYQVLVAHDGLEALELFKK
                     KPIDLIITDVMMPRMDGYDLISEVQYLSPEQPFLFITAKTSEQDKIYGLSLGADDFIA
                     KPFSPRELVLRVHNILRRLHRGGETELISLGNLKMNHSSHEVQIGEEMLDLTVKSFEL
                     LWILASNPERVFSKTDLYEKIWKEDYVDDTNTLNVHIHALRQELAKYSSDQTPTIKTV
                     WGLGYKIEKPRGQT"
     gene            complement(2909..>3280)
                     /locus_tag="VVR63_002063"
     CDS             complement(2909..>3280)
                     /locus_tag="VVR63_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEU6130027.1"
                     /translation="LDNIVATKKVTIKINVKETSDTANGSLSPSNSGSGVTPMNHNHA
                     TGTTDSMPADTMTSSTNTMAGENMAASANKMSDTMMSEDKAMLPNTGETQTSMASIGF
                     LGLALAGLLGGLGLKNKKEEN"
BASE COUNT          917 a          738 c          627 g          998 t
ORIGIN      
        1 ccataaaaga ttataccaca ttgtgtacta tttttggttc attttactat atcactttgg
       61 actatatcgg tctagttatg tctaaacgat tatagctgga tactaagaga aatcaaaaaa
      121 gcactaaggg agaacgtccc aaagtgctta atatcaaggc ctcaaagcct atcttattca
      181 ataaaatatt acaacatttt gttgtagaat tcaacgacaa gtgcttcgtt gatttctggg
      241 ttgatttcgt cgcgttctgg caagcgagtc aatgaacctt ccaatttttc agcgtcgaat
      301 gatacgaatg ctggacgtcc aagagtagct tctactgctt caaggattgc tggaactttc
      361 aatgattttt cacgaactga gatcacttga cctggagtta cgcggtatga tgggatatca
      421 acgcgtttcc cgtcaacaag gatgtgaccg tggtttacaa attgacgagc ttgacgacga
      481 gtagtcgcga gaccaagacg gtaaacaacg ttatccaaac gacgttccaa aagaagcata
      541 aagttgaaac ctaggattcc gcctttgatt tttgtagctt gtacgaacaa gttacggaat
      601 tgtttttcac ctacaccgta agtgaaacga agtttttgtt tttcagccaa ttgcaaaccg
      661 tattctgaca atttagaacg gttgtttggt ccgtgttgtc ctggtacgta gttacgacgt
      721 gccaattctt tacctgtacc tgtaagtgaa aggccaaggc gacgagcttg tttccaagat
      781 ggtcctgtat aacgtgacat atgaatgtcc tcctgatata aataatattt cggtggaaat
      841 agtcacttag aaagccctga ttcgtgcaga tgcccttcgc ctaaacagcc aaggttactt
      901 atcataagac acctgttgac gagcttcatg ctttcctgct gatatttcac acaaaatcca
      961 ttctaccatg aatagctgga tttgtaaagg ggttttaggc tttattttca ctaccagaga
     1021 ggttgagaac gagggtaaag gtacttccta gaccgtactg gctgctgact gtgatttccc
     1081 cacccaattg atgggccaat tcacgcgcaa tcgcaagtcc taatccatga ccacctgtct
     1141 tcatgttacg cgaagtttcg acacgataaa ggcgtttgaa aatattttcc aaatcctctg
     1201 gggcaatacc ctgcccttca tcggtcacac tgattgaaag ctggtccttc tccagcttag
     1261 ccaccacttc cagcttggtt cctggagcag aatatttaaa agcgttatcg accagattca
     1321 ccaagatacg agaaagctta gcataatctc cctcaatccg ggcagactct gggattacct
     1381 gcaagtggac atctcttctc tcctgctcaa tcaaaaactg aaattcactc atgcactcaa
     1441 ttaagagctt gtccagaaaa atactgtctt tactggtagt ttccacctga tttctagctg
     1501 tgtttagggt caaaaaattc aactcctcaa ccagtttatt gagcctctcc gtctggcgtc
     1561 caatggttgc tagataatga gcttgctccg actccttgat aatcccatcc aaaatccctt
     1621 ctaccgtcgc ttggatcgaa gtgatagggg tcttaatatc atgcgacaac tgggcaatca
     1681 tcaagccctt ttctcgttcg ctttcttcca aggaatcaaa gcttacctgc aaatcatggg
     1741 acatctcatt aaaagtttgc cctaattgct gaaattctac aggaccttga acctccaaat
     1801 ttgaaggaaa atccttggcc gctacccgct tggcatgctc cttgagtttg cccaacgacg
     1861 taaagactgg caataggaga aagagactaa tcccagcacc gacaaggctg gcaacgatgg
     1921 tcatcccaag caaaaagtaa atctcgcctt tcgcaatcag cattttttga acagcccaaa
     1981 aaacaaccaa aatggttaag agggttgaaa taatatatcc aaccaaaata taacttttta
     2041 gtttcatgtt tgtcctctcg gtttctctat cttatatccc aacccccaaa ctgtcttaat
     2101 agtgggagtt tggtcactac tatattttgc cagctcctgt cgaagagcat ggatatgcac
     2161 attcaaggta ttggtgtcat ccacgtagtc ttctttccag atcttttcat agaggtctgt
     2221 cttggagaaa actcgctctg gattgctagc taaaatccac agcaattcaa atgatttaac
     2281 agttaaatcc agcatttctt ctcctatttg aacttcatga ctactatgat tcatttttag
     2341 attgccaagg gaaatcagct ctgtttcgcc cccacgatga aggcggcgca aaatattgtg
     2401 gacacgcaaa accagctcac gtgggctaaa aggcttagca ataaaatcat ctgctcccaa
     2461 gctcaggccg taaatcttgt cctgttcact ggtcttagca gtaataaata ggaaaggctg
     2521 ctctggtgat aagtattgaa cctcactgat taaatcataa ccatccatcc gaggcatcat
     2581 gacatctgtg ataatcaaat caatcggttt tttcttgaac agctctagcg cttccagtcc
     2641 atcatgggct accaagacct gataacctgc ctgaattaag tatctctgat gaatatctgt
     2701 gatttctacc tcgtcgtcaa cgagtaaaat tgtctttccc atctgtctct cctttgataa
     2761 aaacagtgct atactgcttt aagtataaca ctatttttat tgttttacga tgattttaat
     2821 ctgctattga aagaaagtcc tgattgctga ttgagttgtt aaactaatct tagtcagccc
     2881 actatccatc atttatttcc ttagctgatt agttttcttc ttttttgttt ttcaaaccta
     2941 gaccaccgag taaacctgca agcgcaagcc caaggaaacc aatacttgcc attgatgttt
     3001 gagtctcacc agtatttggt agcatagctt tatcctctga catcatcgta tcagacatct
     3061 tgttagcaga agcagccatg ttttcacctg ccatcgtgtt ggtagaactt gtcatggtgt
     3121 cagcaggcat gctatctgta gtacctgtag catgattgtg attcatcgga gtcacgccag
     3181 aaccagagtt agaaggtgat aatgaaccat ttgctgtgtc tgatgtttct ttaacattta
     3241 tcttaatagt gactttttta gttgctacga tgttgtccaa
//
LOCUS       DAVHTH010000108         3096 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.109, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000108 DAVHTH010000000
VERSION     DAVHTH010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3096)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3096)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3096
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.109"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            2..1242
                     /locus_tag="VVR63_002064"
     CDS             join(2..341,341..1242)
                     /locus_tag="VVR63_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEU6130028.1"
                     /translation="MVKLIDRYGIEIVKKGKNRHYSSKLKQEMMDKALLEGCSQRSIS
                     LDYALPNQGMLSFWPAQYKKNGYTIVEKTRGRPAKMGRKRKKTWEEMTELERLQEENE
                     RLRTEVAYLKKFKRVRGKGRSPRARKAETVREMVSGGFRLDFLLETARLARSTYYYQL
                     KQLDGVDKDKEIKTEIQGIDNEHKGNYGYRRIHLELRNRGFVVNHKKVQRLMRILGLT
                     ARIRRKRKYSSYQGEIGKKAENLIQRQFEASRPMEKCYTDVTEFAIPNSTQKLYLSPV
                     LDGFNSEIIAYHLSTSPNLEQVKSMLEQAFTEKYYENTILHSDQGWQYQHDSYHRFLE
                     SKEIQASMSRKGNSPDNGMMESFFGILKSEMFYGYEKNFRSLENLEQAIVDYIDYYNN
                     KRIKVKLKGLSSVQYRTKSFG"
     gene            complement(1477..2085)
                     /locus_tag="VVR63_002065"
     CDS             complement(1477..2085)
                     /locus_tag="VVR63_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001165927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HEU6130029.1"
                     /translation="MQIKFIDKVSNLIMLNLLYVASVVTVIAIGSGESALIATLIKIV
                     RHEESYPYRDFANSFFKDYWKNLGAALISNLPILILLFSLFFLPYIPLPIYIISILRH
                     IGVIYIILHLIATTFLIPLIGRYNNTLKNSLHNSIMLAYKHFFIAVLIRIIEIIPVLL
                     FFILQNQLLVWITLMIFILPSITKYANAFLYNFIFSKYEKLN"
     gene            2251..2421
                     /locus_tag="VVR63_002066"
                     /pseudo
     CDS             2251..2421
                     /locus_tag="VVR63_002066"
                     /inference="COORDINATES: protein motif:HMM:NF013577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
     gene            2410..3021
                     /locus_tag="VVR63_002067"
     CDS             2410..3021
                     /locus_tag="VVR63_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001821036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEU6130030.1"
                     /translation="MTKDILELESQKMSSDTFIDEIKNNYLSIVESTRKLIDGRQIEL
                     AIKLIREANQILMIGVGSSGNAAREFESSLLRIGIISKTVIDTHFQLMHTALLKDNDL
                     IIAFSLSGSTKEVEETLLNAKRKNVKIISITNYSSRNIAKLSDCVLLTSKKESYLEGG
                     SLMAKASQLFIIDVICTRLSLINYEDTICKKEEIASLLSNKVE"
BASE COUNT         1177 a          397 c          568 g          954 t
ORIGIN      
        1 catggtgaaa ttaattgacc gttatggcat agaaatcgtt aaaaaaggga agaatcgtca
       61 ctattcttct aaattgaaac aagaaatgat ggataaagcc ttactggaag gttgttcaca
      121 aagaagtatt agtcttgatt atgccctccc aaaccaagga atgctttcat tttggccggc
      181 acaatacaag aaaaacgggt atactattgt tgagaaaaca agagggagac cagctaaaat
      241 gggacgtaaa cggaagaaga cttgggaaga aatgacagaa ctagaacgac tccaggagga
      301 gaatgaacgc ttacggactg aggtggccta cctaaaaaag ttaaaagagt tagaggaaag
      361 ggacgaagcc ctagagcgag aaaggcagag acagttagag aaatggtttc aggaggattt
      421 cgactagatt ttcttcttga aacagcacgt ttagctcgct cgacttacta ttatcagttg
      481 aaacaactgg atggggttga taaagataaa gagattaaaa ccgaaattca gggcattgat
      541 aatgaacata aaggcaacta tggctatcgt cgaatccatt tagaactaag gaatcgtggt
      601 tttgtggtca atcataagaa agttcaacgg ttgatgagaa ttcttggttt aacggctcga
      661 attcgccgta aacggaagta ttcttcctac caaggagaga ttggcaagaa agcagagaat
      721 ctcattcaac gccagttcga agcatcgagg ccaatggaaa agtgctatac agatgtgaca
      781 gagtttgcca ttccaaatag cacacagaaa ctctatttat caccagtttt agatggtttt
      841 aacagtgaaa tcattgctta tcatctttct acttcgccaa acttagaaca agtgaagagt
      901 atgttagaac aggcctttac agagaaatac tatgagaata cgattctcca tagtgaccaa
      961 ggctggcaat accaacacga ttcttatcat cggttcctag agagtaagga aattcaagca
     1021 tccatgtcac gcaagggcaa cagcccagac aacggcatga tggaatcttt ctttggcatt
     1081 ttaaaatccg aaatgtttta tggctatgag aagaacttta gatctttaga aaaccttgaa
     1141 caagctattg tggactacat tgattactac aacaacaaac gaattaaggt aaaactaaaa
     1201 ggacttagtt ctgtgcagta cagaactaaa tcctttggat aaattatttg tctaattttt
     1261 tggggtcagt acagtattaa ataccatgat cttatgcgtt ttataataaa aaatctgttc
     1321 ttgttttatt tttagaaaat ttactaaaga ctaaaaatat tatgaataat ttaaaaaata
     1381 gtcaggttat atagtttttt gaaattaaaa ttattttatc gttgaaatta gttaaaaatt
     1441 tttataaaat caagatgcaa ggctatgaga tgttctctag tttaattttt catacttcga
     1501 gaatataaag ttatataaaa atgcattagc atattttgtt attgagggaa gtataaaaat
     1561 cattaaagtt atccaaacta gtaattgatt ctgtaatata aagaagagta gaactgggat
     1621 aatttcaata attctaataa gaacggcaat aaaaaaatgt ttataggcta acatgattga
     1681 attgtgtaga gaatttttta aagtgttatt atatctaccg attaaaggaa ttagaaatgt
     1741 tgttgctatt aaatgaagta tgatatatat tactccaata tgtcgtaaga tagaaatgat
     1801 atatataggt aatggtatgt agggtaggaa gaacaaactg aataataaga ttaaaattgg
     1861 taaattagat attaatgctg ctcctaaatt tttccaataa tctttaaaaa aactgtttgc
     1921 gaagtctcta tagggatagg attcctcgtg tcgtacaatt tttattagag ttgctattag
     1981 ggcactttca cctgatccga tagcaataac tgttactact gacgctacat agagtagatt
     2041 taacattata agatttgaaa ctttatcaat aaattttatc tgcatcttta actcctgctg
     2101 tttttatact tataatatca catcatttga gtttcatcaa ctttgaatac attaagaaag
     2161 aatataacta tgaggaaagg aaaaaattat tatgaataaa tccaaaaaat ataaagaaag
     2221 aattcattat gaatacgata atcttactaa atcagagaaa aaattgctga ctatatttta
     2281 gttagagata gtgaaatagt tcatgaaacg tcttcagaaa ttgttagtaa agtaaaagtt
     2341 ggagagggaa ctcttaatcg attttgcaaa aagattggat actctggttt tcaggaacta
     2401 aaattaaaaa tgacgaaaga tatattagag ttagaatctc aaaaaatgag tagtgacaca
     2461 tttattgatg aaataaaaaa taattattta tctattgtgg aaagtacaag aaaattaatt
     2521 gatggtagac aaatagaatt agctataaaa ttaataagag aagcaaacca gattttaatg
     2581 attggtgtgg gttctagtgg aaatgcggct agagaatttg agagtagttt gttaagaatt
     2641 ggaataataa gtaagacggt aattgatacc cattttcaac tcatgcatac tgcgttattg
     2701 aaagataatg atttgataat agcgtttagt ttatctggtt ccacaaaaga agttgaggaa
     2761 actttattaa acgcaaaaag aaaaaatgtt aaaattattt caataacaaa ttattcgtcc
     2821 agaaatatag caaaattatc tgactgcgtt cttttgacat caaaaaaaga atcttattta
     2881 gagggtggta gtttaatggc taaggcttct caactattca taattgatgt aatatgcact
     2941 agactctctt taataaatta tgaagatact atatgtaaaa aagaagagat tgcttctttg
     3001 ctgtcaaata aagtggaata aatcaataat ttttaaattt taataaaaat tttttaaaat
     3061 aaattaaaaa acgatcctaa aagggtcgtt tttttg
//
LOCUS       DAVHTH010000109         2953 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.110, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000109 DAVHTH010000000
VERSION     DAVHTH010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2953)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2953)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2953
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.110"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            18..284
                     /locus_tag="VVR63_002068"
                     /pseudo
     CDS             18..284
                     /locus_tag="VVR63_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000059639.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            434..673
                     /locus_tag="VVR63_002069"
     CDS             434..673
                     /locus_tag="VVR63_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6130031.1"
                     /translation="MKKTVYKKLGISIIASTLLASQLSTVSALSVISSTGEEYEVSET
                     LEKGPESNDSSLSEISPTYGSYYQKQSEVLSVMMI"
     gene            754..1575
                     /gene="cbpG"
                     /locus_tag="VVR63_002070"
     CDS             754..1575
                     /gene="cbpG"
                     /locus_tag="VVR63_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001100143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpG"
                     /protein_id="HEU6130032.1"
                     /translation="MNVEGRGSANFIKDNVLITAAHNYYRHDYGKEADDIYVLPAVSP
                     SQELFGKIKVKEVRYLKEFRNLNSKNAREYDLALLILEEPIGAKLGTLGLPTSQKNLT
                     GITVTITGYLSYNFKIHQMYTDKKQVLSDDGMFLDYQVDTLEGSSGSAVYDASHRVVG
                     VHTLGDGANQINSAVKLNERNLPFIYSVLKGYSLEGWKKINGSWYYYRQHDKQTGWQE
                     INDTWYYLDSSGKMLTDWQKVNGKWYYLNSNRAMVTGSQTIDGKVYNFASSGEWI"
     gene            1594..2616
                     /gene="cbpF"
                     /locus_tag="VVR63_002071"
     CDS             1594..2616
                     /gene="cbpF"
                     /locus_tag="VVR63_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpF"
                     /protein_id="HEU6130033.1"
                     /translation="MKLFKKMMQVVLATFFFGLLGTSTVFADDSEGWQFVQENGRTYY
                     KKGDLKETYWRVIDGKYYYFDPLSGEMVVGWQYIPAPHKGVTIGPSPRQEIAFRPDWF
                     YFGQDGVLQEFVGKQVLEAKTATNTNKHHGEEYDSPAEKRVYYFEDQRSYHTLKTGWV
                     YDDGDWYYLQKDGGFDSRINRLTVGELARGWVKDYPLTYDEEKLKAAPWYYLDPATGI
                     MQTGWQHLGNKWYYLRSSGAMATGWYQEGSTWYYLDAENGDMKTGWQNLGNKWYYLRS
                     SGAMATGWYQEGSTWYYLNASNGDMKTGWFQVNGNWYYAYDSGALAVNTTVGGYYLNY
                     NGEWVK"
     gene            complement(2744..>2953)
                     /locus_tag="VVR63_002072"
     CDS             complement(2744..>2953)
                     /locus_tag="VVR63_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase core domain-containing protein"
                     /protein_id="HEU6130034.1"
                     /translation="KGNSPDNGMMESFFGILKSEMFYGYEKSFQSLKQLEQAIVDYID
                     YYNNKRIKVKLKGLSPVQYRTKSFG"
BASE COUNT          973 a          439 c          648 g          893 t
ORIGIN      
        1 tttgattttc attgagtata aaatggagcc tatcagataa tatctggctg agacgtgtcg
       61 ctattgacca ccagttgtta agaaaagaga agaccaatac tcaattaatg gaaaagattc
      121 tccttcataa cttgaaccaa acagaatttt ttatcaataa agccattggc tggactctgc
      181 gagactactc caaaacgaat cccacttggg taacatgctt tattgagaaa aacaaggaaa
      241 gaatggctga acttagtatc aaagaagcaa gcaagtacct ctagcgtgat tgaaaagcgc
      301 agtcattaat tgaaaagttt acctgtttat gtgataatgg agggtattta aagaaggtgg
      361 tagatttctt gattctatag tagattgaga aatttagaat agtacgctat aattacatta
      421 ggaggatacg ataatgaaga aaactgttta taaaaaattg ggtatttcaa ttattgcgag
      481 tactttattg gctagccagt tatcgacagt atctgctttg agtgttattt ctagtacagg
      541 tgaagaatat gaggtaagtg agacactaga aaaaggtcca gagtctaatg attcttcatt
      601 atctgagatt tcaccaacgt atggttcata ctaccaaaag caatcagaag tattatcggt
      661 aatgatgatt tgattaaaat tgataatact ttacagtatc cgtattcgac ttcagctatg
      721 gttttatcta agtattatgg agtagccgat ggaatgaatg tagaagggag gggaagtgcg
      781 aattttatta aagataatgt gttaattaca gcggctcaca actactacag acatgactat
      841 gggaaagaag cggatgatat ttatgttctt ccggctgtta gtccaagtca agaactattt
      901 ggaaagatca aagtaaagga agttcgttat ttgaaggaat ttagaaattt aaattctaag
      961 aatgcaaggg aatatgactt ggctttatta attctagaag agcccattgg tgcaaaatta
     1021 gggactttgg gtcttcctac tagtcaaaaa aatttgacag gaataactgt gactatcaca
     1081 ggctatctat catataattt taaaattcat caaatgtata cagataaaaa acaagtttta
     1141 agtgatgatg gcatgttctt ggattaccaa gttgatactt tagaggggtc tagtggatct
     1201 gcagtttatg atgctagtca ccgcgtagta ggagtgcata ctttaggaga tggagctaat
     1261 caaattaaca gtgcagttaa attaaatgaa cgaaatttgc catttattta ttcggttctt
     1321 aaaggttact ctcttgaagg atggaagaaa ataaatggta gttggtacta ttatagacaa
     1381 catgataaac aaacgggttg gcaggagata aatgatactt ggtattattt agacagttcc
     1441 ggtaagatgc ttacagattg gcaaaaagta aatggaaaat ggtattatct caattcaaat
     1501 agagcaatgg ttacaggtag ccaaactatc gatggtaaag tttataactt cgcttcatct
     1561 ggtgagtgga tttgatgttg gaggatatat aaaatgaagc tttttaaaaa aatgatgcaa
     1621 gtcgtactag ccacattttt cttcggtttg ctagggacca gtacagtatt tgcagatgat
     1681 tctgaaggat ggcagtttgt ccaagaaaat ggtagaacct actacaaaaa gggggatcta
     1741 aaagaaacct actggagagt gatagatggg aaatactatt attttgatcc tttatccgga
     1801 gagatggttg tcggctggca atatatacct gctccacaca agggggttac gattggtcct
     1861 tctccaagac aagagattgc ttttagacca gattggtttt actttggtca agatggggta
     1921 ctacaagaat ttgttggcaa gcaagtgtta gaagcaaaaa ctgctacaaa taccaacaaa
     1981 catcatgggg aagaatatga tagcccagca gagaaacgag tctattattt tgaagatcag
     2041 cgtagttatc atactttaaa aactggttgg gtttatgatg atggggactg gtattatttg
     2101 cagaaggatg gtggctttga ttctcgcatc aacagattga cggttggaga gctagcacgt
     2161 ggttgggtta aggattaccc tcttacctat gatgaagaga agctaaaagc agctccatgg
     2221 tactatctag atccagcaac tggcatcatg caaacaggtt ggcaacatct tggtaataaa
     2281 tggtactatc tccgttcatc aggagctatg gcaactggtt ggtatcagga aggttcaact
     2341 tggtactatt tagatgctga aaatggcgat atgaaaactg gttggcaaaa ccttgggaac
     2401 aaatggtact atctccgttc atcaggagct atggcaactg gttggtatca ggaaggttcg
     2461 acttggtact atctaaatgc aagtaatgga gatatgaaaa caggctggtt ccaagtcaat
     2521 ggtaactggt actatgccta tgattcaggt gctttagctg ttaataccac agtaggtggt
     2581 tactacttaa actataatgg tgaatgggtt aagtaatgaa ggctaattgt aaactgtgat
     2641 ggatacttaa ctttgtataa taggtggata aaagtcttca caatcaaaaa acgcatagta
     2701 tcaaggtttt tctgtactgc cccccaaaag ttagacaaat aatttatccg aaggatttag
     2761 ttctgtattg cacagggcta agtcctttta gttttacctt aattctctta ttgttgtagt
     2821 aatcaatata gtctacaatg gcttgttcca attgcttaag cgactgaaat gacttctcat
     2881 aaccataaaa catctccgat ttcagaatgc caaagaagga ctccatcata ccgttgtctg
     2941 ggctgttacc ttt
//
LOCUS       DAVHTH010000110         2920 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.111, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000110 DAVHTH010000000
VERSION     DAVHTH010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2920)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2920)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2920
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.111"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            complement(63..1004)
                     /locus_tag="VVR63_002073"
     CDS             complement(63..1004)
                     /locus_tag="VVR63_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEU6130035.1"
                     /translation="MKQTKRIKRWRYYLRRFAYQIKILRVLQSISREKYDEKISASLV
                     YGFLSAVAVNFFFQPGHVYSSGATGLAQIISALSNHWFGFHIPISLSFYAINFPLMVL
                     AWYQIGHKFTVFTFITVSMSSFFIQFVPVATLTEDPIINSLFGGVVMGLGIGFALRNN
                     ISSGGTDIVSLTIRKKTGKNVGSISFLVNGTIMLIAGLTFGWKYALYSMITIFVSSRV
                     TDAVFTKQKRMQAMIVTNHPEKVIEKIHKKLHRGATMIHDAEGTYNHERKAVLITVIT
                     RAEFNEFKQIMTQVDPSSFVSVSENVHILGRFVEIDN"
     gene            complement(982..2745)
                     /gene="aspS"
                     /locus_tag="VVR63_002074"
     CDS             complement(982..2745)
                     /gene="aspS"
                     /locus_tag="VVR63_002074"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HEU6130036.1"
                     /translation="MKRSMYAGRVREEHIGQEITLKGWVGRRRDLGGLIFIDLRDREG
                     IMQLVINPEKVSAEVMATAESLRSEFVIEVTGQVAAREQANDKLPTGAVELNVTALIV
                     LNTAKTTPFEIKDGIEANDDTRLRYRYLDLRRPEMLENLKLRAKVTHSIRNYLDELEF
                     IDVETPFLSKSTPEGARDYLVPSRVNKGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLTEQEIQDITEGLIARVMKETKGIEVTLPFPRMKY
                     DDAMALYGSDKPDTRFDMLLQDLTEVVKGVDFKVFSEAPAVKAIVVKGAADNYSRKDI
                     DKMTEVAKQYGAKGLAWVKVVDGELNGPVAKFLTGIQEELTTALALEDKDLVLFVADT
                     LEVANATLGALRGRIAKELGLIDNDKFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPQ
                     EETAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKDLQERMFKALGFSTEEANDQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGEENIREVIAFPKNNKATDPMTQAPSTV
                     ALKQLEELSLQVEEDETNKTN"
BASE COUNT          847 a          687 c          587 g          799 t
ORIGIN      
        1 aacatatata cggcaaggtg aagctgacgt ggtttgaaga gattttcgaa gagtattaat
       61 cactaattat ctatctcaac aaatcttcct agaatatgaa cattttccga gacagagaca
      121 aaggagcttg gatccacttg tgtcataatc tgtttaaatt cattaaactc tgcacgtgta
      181 atgacagtga ttaaaactgc ctttctctcg tgattatagg ttccttctgc atcgtggatc
      241 atggttgctc cgcggtgcaa ttttttatgg attttttcaa ttaccttctc tggatgattt
      301 gtcacaatca tggcctgcat acgcttttgc ttagtaaaga ctgcgtctgt cacacggcta
      361 gagacaaaga tggtaatcat agaataaaga gcgtatttcc aaccaaaggt caaacctgct
      421 atcagcatga tagttccatt taccaagaaa gaaatactac cgacattctt acccgttttc
      481 ttgcgaatag tcaggctgac gatatccgtc ccaccactgg agatattgtt tcgaagagca
      541 aaaccaatcc ccaaacccat aacaacaccc ccaaaaaggg aattgataat gggatcctcc
      601 gtcaaggttg ccacagggac aaactggata aagaaggaac tcatagatac cgtgataaag
      661 gtaaagacgg tgaacttatg gccaatctga taccaagcta agaccatcaa agggaagtta
      721 atggcgtaga agcttagcga aatcggaata tgaaaaccaa accagtgatt actcaaggca
      781 gagataatct gtgccagacc tgttgcacca ctcgaataca catgccctgg ttggaaaaag
      841 aaattaactg ctactgctga taaaaaacca tagaccagag aggccgaaat cttctcatca
      901 tacttttctc gagagatact ttgtaagaca cgtaaaattt ttatctgata agcaaagcgg
      961 cgcagataat agcgccaccg cttaattcgt tttgtttgtt tcatcttctt ctacttgtaa
     1021 gctgagttcc tctagttgtt tgagagcgac tgttgatgga gcttgtgtca ttgggtcagt
     1081 tgccttgttg ttcttaggaa aggcaatgac ttcacggata ttttcttctc cagcaagcaa
     1141 catgacaaaa cggtcaagcc cgatagccaa accaccgtgt ggtgggaaac catagtccat
     1201 ggcttcaaga aggaaaccaa actggtcatt ggcttcttca gttgagaaac caagagcctt
     1261 gaacatgcgt tcttgaaggt ctttttggtt gatacgaagg ctaccaccac caagctcata
     1321 accgttcaag acgatatcgt aagcaatggc acgaacctta gccaaatcac cttctaattc
     1381 gtgagcagtc tcttcctgtg gaagtgtgaa tggatggtgg gcgctcatgt agcggccttc
     1441 ttcttcagac cattcaaaca tcggccagtc aaccacccaa aggaagttga acttatcatt
     1501 atcaatcaag ccaagctctt tagcaatacg tccacgaagg gcacccagtg ttgcattagc
     1561 cacttcaagc gtatccgcca caaagagaac caagtcctta tcttcaagag caagcgctgt
     1621 tgtcaattct tcttggatac cagtcaagaa cttggcaact ggtccgttta attctccatc
     1681 aaccaccttg acccaagcaa gacctttggc accatactgt ttggctactt ccgtcatctt
     1741 gtcgatgtct ttacgtgaat agttgtccgc agctcctttg accacaatcg cttttacagc
     1801 aggtgcttct gaaaagactt taaagtctac acctttgacc acttctgtca agtcctgaag
     1861 caacatgtca aaacgagtat ctggcttgtc agaaccgtaa agagccatag catcatcgta
     1921 tttcatacga gggaacggta gcgttacttc gatgcctttt gtttccttca tcacgcgcgc
     1981 gatcaagcct tctgtaatat cttggatttc ttgctcagta aggaaggacg tttccaagtc
     2041 gacctgagta aattcaggct ggcggtctcc acgcaagtcc tcgtcacgga aacatttaac
     2101 gatttggtag taacggtcaa aaccagcatt catcaagagc tgtttcgtga tttgtggact
     2161 ttgaggaaga gcgtaaaaat gccccttatt aacacgagac ggcactaaat aatcacgcgc
     2221 cccttcaggc gttgacttag aaaggaatgg tgtctccacg tcgataaact ccaactcatc
     2281 caagtagttg cggatagagt gggtcacctt ggcacgaagt ttaagatttt ccaacatttc
     2341 tggacgacga aggtcaaggt aacggtaacg caaacgtgta tcgtcatttg cctcaatgcc
     2401 atccttaatc tcaaatggtg ttgtcttagc tgtgttaagc acaataagag ctgtcacgtt
     2461 taactcaacc gcaccagttg gcaacttatc attggcttgc tcacgcgcag cgacctgacc
     2521 agtcacctca ataacaaatt cgctacgaag gctttcagct gttgccataa cctctgcaga
     2581 tactttttca gggttgataa ccaactgcat gattccttca cggtcacgaa gatcgataaa
     2641 gatcaaacca ccaaggtcac gacgacggcc aacccatcct ttcaaggtta tttcttgtcc
     2701 gatgtgttcc tcacgaacac gaccagcata catactacgt ttcattattt ctctcctctt
     2761 ttattctgtt actattttac cataaaagcg caggctcttc atgaaaatca tcagaaaagt
     2821 ttgccagtct ttaaaagtca ggtgaaagcc ctaaaaatta gcgctaatac tcttcgaaaa
     2881 tctcttcaaa ccacgtcagc gtcgccttac cgtaggtatg
//
LOCUS       DAVHTH010000111         2709 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.112, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000111 DAVHTH010000000
VERSION     DAVHTH010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2709)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2709)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2709
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.112"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            <1..2537
                     /locus_tag="VVR63_002075"
     rRNA            <1..2537
                     /locus_tag="VVR63_002075"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            2614..>2709
                     /gene="rrf"
                     /locus_tag="VVR63_002076"
     rRNA            2614..>2709
                     /gene="rrf"
                     /locus_tag="VVR63_002076"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT          757 a          553 c          794 g          605 t
ORIGIN      
        1 cgtatttaaa atagtctttg tacttagcag tatcctgagt acggcgggac acgtgaaatc
       61 ccgtcggaat ctgggaggac catctcccaa ccctaaatac tccctagtga ccgatagtga
      121 accagtaccg tgagggaaag gtgaaaagca ccccgggagg ggagtgaaat agaacctgaa
      181 accgtgtgcc tacaacaagt tcgagcccgt taatgggtga gagcgtgcct tttgtagaat
      241 gaaccggcga gttacgttat gatgcgaggt taagttgaag agacggagcc gtagggaaac
      301 cgagtctgaa tagggcgcct tagtatcatg acgtagaccc gaaaccatgt gacctaccca
      361 tgagcaggtt gaaggtgcgg taagacgcac tggaggaccg aaccagggca cgttgaaaag
      421 tgcttggatg acttgtgggt agcggagaaa ttccaaacga acttggagat agctggttct
      481 ctccgaaata gctttagggc tagcgtcgac attagagatt cttggaggta gagcactgtt
      541 tgggtgaggg gtccatcccg gattaccaat ctcagataaa ctccgaatgc caatgaatta
      601 tggtcggcag tcagactgcg agtgctaaga tccgtagtcg aaagggaaac agcccagacc
      661 accagctaag gtcccaaaat aattgttaag tggaaaagga tgtggggttg cacagacaac
      721 taggatgtta gcttagaagc agctattcat tcaaagagtg cgtaatagct cactagtcga
      781 gtgaccctgc gccgaaaatg taccggggct aaaacaattt accgaagctg tggatacctt
      841 tataggtatg gtaggagagc gttctatgtg tgatgaaggt ataccgtgag gagtgctgga
      901 acgcatagaa gtgagaatgc cggtatgagt agcgaaagac aggtgagaat cctgtccacc
      961 gtaagactaa ggtttccagg ggaaggctcg tccgccctgg gttagtcggg acctaaggag
     1021 agaccgaaag gtgtatccga tggacaacag gttgatattc ctgtactaga gtatgtagtg
     1081 atggagggac gcagtaggct aactaaagca gacgattgga agagtctgtc taagcagtga
     1141 ggtgtgaatt gagtcaaatg cttaattcta taacattgag ctgtgatggg gagcgaagtt
     1201 tagtagcgaa gttagtgacg tcacactgcc aagaaaagct tctagcgttt aaacatactc
     1261 tacccgtacc gcaaaccgac acaggtagtc gaggcgagta gcctcaggtg agcgagagaa
     1321 ctctcgttaa ggaactcggc aaaatgaccc cgtaacttcg ggagaagggg tgctgacttt
     1381 aagtcagccg cagtgaatag gcccaagcaa ctgtttatca aaaacacagc tctctgctaa
     1441 atcgtaagat gatgtatagg gggtgacgcc tgcccggtgc tggaaggtta agaggagtgc
     1501 ttagcgtaag cgaaggtatg aattgaagcc ccagtaaacg gcggccgtaa ctataacggt
     1561 cctaaggtag cgaaattcct tgtcgggtaa gttccgaccc gcacgaaagg cgtaatgatt
     1621 tgggcactgt ctcaacgaga gactcggtga aattttagta cctgtgaaga tgcaggttac
     1681 ccgcgacagg acggaaagac cccatggagc tttactgcag tttgatattg agtgtctgta
     1741 ccacatgtac aggataggta ggagtctaag agatcgggac gccagtttcg aaggagacgc
     1801 tgttgggata ctacccttgt gttatggcca ctctaaccca gataggtgat ccctatcgga
     1861 gacagtgtct gacgggcagt ttgactgggg cggtcgcctc ctaaaaggta acggaggcgc
     1921 ccaaaggttc cctcagaatg gttggaaatc attcgcagag tgtaaaggta taagggagct
     1981 tgactgcgag agctacaact cgagcaggga cgaaagtcgg gcttagtgat ccggtggttc
     2041 cgtatggaag ggccatcgct caacggataa aagctaccct ggggataaca ggcttatctc
     2101 ccccaagagt tcacatcgac ggggaggttt ggcacctcga tgtcggctcg tcgcatcctg
     2161 gggctgtagt cggtcccaag ggttgggctg ttcgcccatt aaagcggcac gcgagctggg
     2221 ttcagaacgt cgtgagacag ttcggtccct atccgtcgcg ggcgtaggaa atttgagagg
     2281 atctgctcct agtacgagag gaccagagtg gacttaccgc tggtgtacca gttgtcttgc
     2341 caaaggcatc gctgggtagc tatgtaggga agggataaac gctgaaagca tctaagtgtg
     2401 aaacccacct caagatgaga tttcccatga ttatatatca gtaagagccc tgagagatga
     2461 tcaggtagat aggttagaag tggaagtgtg gcgacacatg tagcggacta atactaatag
     2521 ctcgaggact tatccgaagt aactgagaat atgaaagcga acggttttct taagttgaat
     2581 agatattcaa ttttgagtag gtattactca gagttaagtg acgatagcct aggagataca
     2641 cctgtaccca tgccgaacac agaagttaag ccctagaacg ccggaagtag ttgggggttg
     2701 ccccctgtg
//
LOCUS       DAVHTH010000112         2487 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.113, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000112 DAVHTH010000000
VERSION     DAVHTH010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2487)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2487)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2487
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.113"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            complement(173..838)
                     /locus_tag="VVR63_002077"
     CDS             complement(173..838)
                     /locus_tag="VVR63_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HEU6130037.1"
                     /translation="MSDRTIGILGLGIFGSSVLAALAKQDMNIIAIDDHAERINQFEP
                     VLARGVIGDITDEELLRSAGIDTCDTVVVATGENLESSVLAVMHCKSLGVPTVIAKVK
                     SQTAKKVLEKIGADSVISPEYEMGQSLAQTILFHNSVDVFQLDKNVSIVEMKIPQSWA
                     GQSLSKLDLRGKYNLNILGFREQENSPLDVEFGPDDLLKADTYILAVINNQYLDTLVA
                     LNS"
     gene            complement(852..2231)
                     /locus_tag="VVR63_002078"
     CDS             complement(852..2231)
                     /locus_tag="VVR63_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000897732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEU6130038.1"
                     /translation="MLFKLSKEKIELGLSRLSPARRIFLSFALVILLGSLLLSLPFVQ
                     VESSRATYFDHLFTAVSAVCVTGLSTLPVAHTYNIWGQIICLLLIQIGGLGLMTFIGV
                     FYIQSKQKLSLRSRATIQDSFSYGETRSLRKFVYSIFLTTFLVESLGAILLSFRLIPQ
                     LGWGRGLFSSIFLAISAFCNAGFDNLGSTSLFAFQTDLLVNLVIAGLIITGGLGFMVW
                     FDLAGHVGRKKKGRLHFHTKLVLLLTIGLLLFGTATTLFLEWNNAGTIGNLPVADKVL
                     VSFFQTVTMRTAGFSTIDYTQAHPVTLLIYILQMFLGGAPGGTAGGLKITTFFVLLVF
                     ARSELLGLPHANVARRTIAPRTVQKSFSVFIIFLMSFLIGLILLGITAKGNPPFIHLI
                     FETISALSTVGVTANLTPDLGKLALSVIMPLMFMGRIGPLTLFVSLADYHPEKKDMIH
                     YMKADISIG"
BASE COUNT          818 a          566 c          462 g          641 t
ORIGIN      
        1 cccgcagcta gtttcctagt ttgatctttg attttcattg agtattactc tctcttgtca
       61 cttccttcta ttttaccata aagtccagcc tttgaagaac ttttactaga agacaagggg
      121 cttctgtctc tatttgccat cttaagcatc aaaaaagagg ggtcatccct ctttacgaat
      181 tcaatgctac tagggtatcc aaatactggt tgttgatgac tgccaaaata taggtatctg
      241 ctttcaagag gtcatctggt ccaaattcaa catccaatgg ggaattttcc tgctctcgga
      301 aacccaaaat attcagattg tatttgccac ggaggtctaa tttactcaga ctttgacctg
      361 cccaagactg aggaattttc atctccacga tagacacatt tttatccaac tgaaagacat
      421 caacactatt atggaaaaga atggtctgtg ctagagactg ccccatttca tactctggcg
      481 agataaccga gtcagctcca atcttttcta gcactttctt agcggtctga cttttgacct
      541 tagcaataac agtcggtacc cccaaactct tacagtgcat aaccgcaagc acactcgact
      601 ccagattttc acctgtcgcg actacaacgg tatcgcaggt atcaatccct gctgatctca
      661 ataattcttc atctgtgatg tcaccaatca ctccacgcgc caaaactggc tcaaactgat
      721 tgatgcgctc tgcgtggtca tcaatagcga taatattcat atcctgcttg gctagggcag
      781 ctaggacact gctcccaaaa attcccaagc ccaaaattcc aatcgtacga tctgacatgc
      841 tctttccttt cttaaccaat actaatatct gctttcatat agtgaatcat atctttcttt
      901 tctggatggt aatctgccaa gctaacaaac aaggtcaagg gaccaattcg tcccataaac
      961 ataagtggca tgataacact gagagccaat ttcccaaggt caggagtcag atttgccgtt
     1021 acaccaactg tactaagagc tgaaatggtt tcaaatatga ggtggataaa gggaggattg
     1081 cctttggctg ttatccctag cagaatcaat cctatcaaga agctcatcaa aaagataata
     1141 aagacactaa aggatttttg aaccgttcgc ggcgcgatcg ttcgtctcgc aacattggca
     1201 tgaggcaagc ctagaagctc acttcgtgca aagaccaaga ggacaaaaaa tgtcgtaatc
     1261 ttgagtcccc cagctgttcc tccaggtgcc ccacctagaa acatctgtaa gatataaatc
     1321 aaaagagtca caggatgagc ctgagtataa tctatcgtag aaaagccagc tgttcgcatc
     1381 gtcactgttt gaaaaaagct aactaaaacc ttatcggcaa cagggagatt gccaatcgtt
     1441 ccagcattgt tccactcaag aaagagagta gttgccgttc caaataacaa caaacctata
     1501 gtcaataata atacaagctt cgtatgaaag tgcagacgtc cttttttctt tcttcctaca
     1561 tgaccagcca aatcaaacca gaccataaaa ccaaggccgc ctgtaataat caagcctgca
     1621 atcaccagat tgaccagtaa atcggtctga aaagcaaata aactggtgct ccctaaatta
     1681 tcaaaaccgg cattacagaa ggctgagatc gctagaaaaa tggaactaaa aagaccacgt
     1741 ccccagccaa gttgaggaat aaggcgaaaa ctaagcaaaa tagctcccaa gctctcaacc
     1801 aaaaaggtcg tgagaaaaat agaatagaca aactttctca aagatcgagt ttctccataa
     1861 ctaaaactat cctgaatagt tgcacggcta cgaagactaa gcttttgctt gctctggata
     1921 tagaaaaccc caataaaggt catgagccct agaccaccga tctgaatcaa gagcaaacag
     1981 attatttggc cccagatatt ataggtgtga gctactggaa gggttgagag acctgtcaca
     2041 cagactgcag agacagcagt gaaaagatga tcaaaataag tcgctcgtga gctttcaact
     2101 tggacaaagg gcaagctcaa aagaagagag cctagtaaaa tgaccaaggc aaaactcaaa
     2161 aaaatacgac gggctggcga taaacgagat aagcctagct ctattttttc cttagataat
     2221 ttgaataaca tgtttccatt gtaccataaa aagctcgaaa tgacttagat aggataaggc
     2281 aaaattcact aacaccaagc ctaaaaaatg ccaccttttt attgatagct taggcaagaa
     2341 caatacttga tagatatgac tataggtcaa aaaagcaaga caggagcttt taacgccagc
     2401 tactctatat gcttttcagg agaaaatttc tctttttgat tataggcaat gaaaaccaag
     2461 gcatcgatta gaaagctagt cacaggt
//
LOCUS       DAVHTH010000113         2406 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.114, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000113 DAVHTH010000000
VERSION     DAVHTH010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2406)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2406)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2406
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.114"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            complement(96..326)
                     /locus_tag="VVR63_002079"
     CDS             complement(96..326)
                     /locus_tag="VVR63_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000901571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEU6130039.1"
                     /translation="MLGSMFVGLLVGFLAGTLTNRGEHMGCFGKMFLGWIGAFIGHLL
                     FGTWGPIIAGTAIIPAVLGSMIVLAIFWRRGS"
     gene            complement(336..1577)
                     /locus_tag="VVR63_002080"
     CDS             complement(336..1577)
                     /locus_tag="VVR63_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HEU6130040.1"
                     /translation="MVLPNFKENLEKYAKLLVANGINVQPGHTLALSIDVEQRELAHL
                     IVKEAYALGAHEVIVQWTDDVINREKFLHAPMERLDNVPEYKIAEMNYLLENKASRLG
                     VRSSDPGALNGVDADKLSASAKAMGLAMKPMRIATQSNKVSWTVAAAAGLEWAKKVFP
                     NAASDEEAVDFLWDQIFKTCRVYEADPVKAWEEHAAILKSKADMLNKEQFSALHYTAP
                     GTDLTLGLPKDHVWESAGAINAQGEGFLPNMPTEEVFTAPDFRRADGYVTSTKPLSYN
                     GNIIEGITVTFKEGQIVDITAEKGDQVMKDLVFENMGARALGECVLVPDPSPISQSGI
                     TFFNTLFDENASNHLAIGAAYATSVVGGAEMSEEELEAAGLNRSDVHVDFMIGSSQMD
                     IDGIREDGTRVPLFRNGDWAN"
     gene            complement(1599..1751)
                     /locus_tag="VVR63_002081"
     CDS             complement(1599..1751)
                     /locus_tag="VVR63_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6130041.1"
                     /translation="MKLRIFAEDKPAEKVFEYQLELADQTILLSTALLSGAIALAGLF
                     SALKEK"
     gene            complement(1772..2049)
                     /locus_tag="VVR63_002082"
                     /pseudo
     CDS             complement(1772..2049)
                     /locus_tag="VVR63_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013904578.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system YafQ family
                     toxin"
     gene            complement(2042..2305)
                     /locus_tag="VVR63_002083"
     CDS             complement(2042..2305)
                     /locus_tag="VVR63_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HEU6130042.1"
                     /translation="MSKTSMSIRLDSEVKEQAQQVFSNLGMDMTTAVNIFLRQAIQYQ
                     GLPFDVRLDENRKLLQVLTDLDQNRNMSQSFESVSDLMEDLRA"
BASE COUNT          697 a          592 c          416 g          701 t
ORIGIN      
        1 agttctatct acaacctcaa agcagtgatt tgagcaacct gcggctagtt tcctagtttg
       61 ctctttgatt ttcattgagt atcagattta ggaaattaac ttcctcgtct ccaaaaaata
      121 gctaaaacaa tcatggaacc tagtactgcc ggaataatgg cagttcctgc tattatcggt
      181 ccccaagtcc caaaaagcaa atggcctata aaggcaccaa tccatccgag aaacattttt
      241 ccaaaacatc ccatgtgttc tccacgattg gtcagagtac ctgctaaaaa tcccactagg
      301 agaccaacga acatacttcc taacatatta tctccttaat ttgcccaatc tccgttacgg
      361 aagagtggta cacgtgtccc atcctcacgg ataccatcga tatccatttg actagaccca
      421 atcataaagt ccacgtgaac atctgaacgg ttaagccccg cagcttcaag ctcctcttcg
      481 ctcatctccg ctccaccaac tacgctagtc gcataagctg caccgatagc caagtgattt
      541 gacgcatttt catcgaaaag ggtgttaaag aaggtaatgc ctgactgaga aattgggctt
      601 ggatctggta ccaatacaca ttcacccaag gcacgcgcac ccatattttc aaagacaagg
      661 tctttcatga cctgatcacc cttctcagca gtgatatcta cgatttgacc ttctttgaag
      721 gttactgtaa ttccttcgat gatatttccg ttatagctaa gcggttttgt agaagttaca
      781 tagccatctg cacgacggaa atcaggcgct gtgaaaactt cctctgtagg catatttggc
      841 aagaatcctt cgccctgtgc attgatagca ccagctgatt cccaaacgtg gtccttcggc
      901 aaacccagtg tcaaatctgt ccctggcgct gtatagtgaa gggctgaaaa ttgctcttta
      961 ttaagcatat cggccttgct cttcaagata gctgcatgct cttcccaagc cttaacagga
     1021 tctgcttcgt agactcggca agttttgaag atttgatccc aaaggaaatc gactgcttct
     1081 tcgtcgctcg cagcatttgg aaagactttc ttagcccact caagtccagc agcggctgcc
     1141 acagtccagc taaccttgtt ggattgcgtt gcgatgcgca ttggcttcat agcaagtccc
     1201 atagctttag cagaagccga aagcttgtca gcgtccactc cgttcaaggc acctgggtca
     1261 gaagaacgaa ctccaagacg gctagccttg ttctccaaaa gatagttcat ctcagcaatc
     1321 ttgtattctg gcacattgtc caaacgctcc atcggcgcat ggaggaattt ctcacggtta
     1381 atgacatcat ctgtccactg aacaataacc tcatgcgcac ccaaagcata agcttctttg
     1441 acaattaagt gagccaactc acgttgctcc acatcgatag agagagccaa agtgtgacca
     1501 ggttgcacgt tgattccgtt cgcaaccaat aatttcgcat atttttctag attttcttta
     1561 aaatttggta aaaccatgta attttctctt ttctattttt atttttcttt caaagcagag
     1621 aataatcctg ctaaagcaat agcacctgac aagagtgctg ttgatagaag aattgtttga
     1681 tcagcaagtt ccaattgata ttcaaatacc ttctcagccg gcttatcttc cgcaaaaatt
     1741 cttagtttca tgagaacccc cttaaaattt attaaaacaa atcactatga ctacctgtcc
     1801 tcagcaaatt taaaatcaat tcttccttgt ctactttata aaccaaaagc caatctggct
     1861 ggatatggca ctcacgaact ccttgaaaat gcttggatgc cgtcaattga tgatcacgat
     1921 atctagcagg aagttctttt tcttgaacca gatcttcaaa acttcttcta ataattctgc
     1981 attcaaacca cgcttcatag ccaacttaaa atctttttta aactgcttat ggtaacgaat
     2041 cttaagcacg caagtcctcc atcaagtctg agactgattc aaaagattga ctcatattac
     2101 gattttggtc taaatccgtt aacacttgaa gcaacttcct attttcgtct agtctaacat
     2161 caaaaggcaa tccctgatat tgaatagctt gacgaaggaa aatattaaca gccgttgtca
     2221 tatccattcc cagattacta aacacctgtt gagcctgctc cttaacctca ctatccagac
     2281 ggatgctcat actcgtcttt gacatactac caccctcttt ctatagacta ttttaacaaa
     2341 aaagaaggct aatgtaaatc tattggatat acattagcct tcttcagata gatgattaaa
     2401 caattt
//
LOCUS       DAVHTH010000114         2379 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.115, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000114 DAVHTH010000000
VERSION     DAVHTH010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2379)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2379)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2379
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.115"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            42..581
                     /locus_tag="VVR63_002084"
     CDS             42..581
                     /locus_tag="VVR63_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU6130043.1"
                     /translation="MKLLSIAISSYNAAAYLHYCVESLVIGGEQVGILIINDGSQDQT
                     QEIAECLASKYPNIVRAIYQENKGHGGAVNRGLAEASGRYFKVVDSDDWVDPRAYLKI
                     LETLQEFESKGQEVDVFVTNFVYEKEGQSCKKSMSYDSVLPVRQIFGWDQVGNFSKGQ
                     YIMMHSLIYRTDLLRASQF"
     gene            648..1058
                     /locus_tag="VVR63_002085"
     CDS             648..1058
                     /locus_tag="VVR63_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="HEU6130044.1"
                     /translation="MYYLPVDFYRYLIGREDQSVNEQVMIKCIDQQLKVNRLLVDQLD
                     LSQVSHPKMREYLLNHIEITTVISSTLLNRSGTAEHLAKKRQLWTYIQQKNPEVFQAI
                     RKTMLSRLTKHSVLPDRKLSNVVYQITKSVYGFN"
     gene            1174..>2379
                     /locus_tag="VVR63_002086"
     CDS             1174..>2379
                     /locus_tag="VVR63_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PavB family fibronectin-binding SSURE repeat
                     adhesin"
                     /protein_id="HEU6130045.1"
                     /translation="MKFNPNQRYTRWSIRRLSVGVASVVVASGFFVLVGQPSSVRADV
                     VNPTPGQVLPEETSGTKEGDLSEKPGDTVLTQAKPEGVTGNTNSLPTPTERTEVSEET
                     NSSSLDTLFEKDEEAQKNPELTDVLKETVDTADVDGTQASPAETTPEQVKGGVKENTK
                     DSIDVPAAYLEKAKGEGPFTAGVNHVIPYELFAGDGMLTRLLLKASDKAPWSDNGDAK
                     NPALSPLGENVKTKGQYFYQLALDGNVAGKEKQALIDQFRANGTQTYSATVNVYGNKD
                     GKPDLDNIVATKKVTININGLISKETVQKAVADNVKDSIDVPAAYLEKAKGEGPFTAG
                     VNHVIPYELFAGDGMLTRLLLKASDKAPWSDNGDAKNPALSPLGENVKTKGQYFYQVA
                     LDGNVAGKEK"
BASE COUNT          738 a          487 c          534 g          620 t
ORIGIN      
        1 gaagagtata agaaaaaatc agtcccctaa aggagcagat tatgaagtta ttgtctatcg
       61 ccatttctag ctataatgca gcagcctatc ttcattactg tgtggagtcg ctagtgattg
      121 gtggtgagca agttgggatt ttgattatca atgacgggtc tcaggatcag actcaggaaa
      181 tcgctgagtg tttagctagc aagtatccta atatcgttag agccatctat caggaaaata
      241 aaggccatgg cggtgcggtc aatcgtggct tggcagaggc ttctgggcgc tattttaaag
      301 tagttgacag tgatgactgg gtggatcctc gtgcctactt gaaaattctt gaaaccttgc
      361 aggaatttga gagtaagggt caagaggtgg atgtctttgt gaccaatttt gtctatgaaa
      421 aggaaggtca gtcttgtaag aagagtatga gttacgattc agtcttgcct gttcggcaga
      481 tttttggctg ggaccaggtc ggaaatttct ccaaaggcca gtatatcatg atgcactcgc
      541 tgatttatcg gacagatttg ttgcgtgcta gccagttcta attgcctgaa catacttttt
      601 atgtcgataa tctctttgtc tttacgcccc ttcagcaggt caagaccatg tactatctgc
      661 ctgtcgattt ctatcgttat ttgattgggc gtgaggacca gtctgtcaat gagcaagtga
      721 tgattaagtg cattgaccag caactcaagg tcaatcgact cttggtagac caacttgatt
      781 tgtcccaagt gagtcatccc aaaatgcgag aatatctgct gaatcatatt gaaatcacga
      841 cggtgatttc cagtaccctg ctcaaccgat ctggaacagc ggagcatctg gcaaaaaaac
      901 gccaattgtg gacctatatt cagcagaaaa atccagaagt ctttcaggct attcgtaaga
      961 ccatgttgag ccgtttgacc aaacattctg tcttgccaga tcgcaaactg tccaatgtcg
     1021 tctatcaaat caccaaatct gtttatggat ttaattaata taagtgtttt ataagaggga
     1081 tttaagaaaa attttaactt tttcttagtc ctttttaatt tcaggagatt atactagagt
     1141 catcaaataa agaaagactc taaggagaat cctatgaaat tcaatccaaa tcaaagatat
     1201 actcgttggt ctattcgccg tctcagtgtc ggtgttgcct cagttgttgt ggctagtggc
     1261 ttctttgtcc tagttggtca accaagttct gtacgtgccg atgtggtcaa tccgacccca
     1321 ggtcaagtct tacctgaaga gacatcggga acgaaagagg gtgacttatc agaaaaacca
     1381 ggagacaccg ttctcactca agcgaaacct gagggcgtta ctggaaatac aaattcactt
     1441 ccgacaccta cagaaagaac tgaagtgagc gaggaaacaa actcttctag tctggataca
     1501 ctttttgaaa aagatgaaga agctcaaaaa aatccagagc taacagatgt cttaaaagaa
     1561 actgtagata cagctgatgt ggatgggaca caagcaagtc cagcagaaac tactcctgaa
     1621 caagtaaaag gtggagtgaa agaaaataca aaagacagta tcgatgttcc agcagcctac
     1681 ctagaaaaag ccaagggtga aggtccattc acagcaggtg tcaaccatgt gattccatac
     1741 gaactcttcg caggtgatgg tatgttgact cgtctcttgc tcaaggcatc tgacaaggca
     1801 ccatggtcag ataacggtga cgctaaaaac ccagccctat ctccactagg tgaaaacgtg
     1861 aagaccaaag gtcaatactt ctatcaatta gccttggacg gaaatgtagc tggcaaagaa
     1921 aaacaagcgc tcattgacca gttccgagca aacggtactc aaacttacag cgctacagtc
     1981 aatgtctatg gtaacaaaga cggtaaacca gacttggaca acatcgtagc aactaaaaaa
     2041 gtcactatta acataaacgg tttaatttct aaagaaacag ttcaaaaagc cgttgcagac
     2101 aacgttaagg acagtatcga tgttccagca gcctacctag aaaaggccaa gggtgaaggt
     2161 ccattcacag caggtgtcaa ccatgtgatt ccatacgaac tcttcgcagg tgatggtatg
     2221 ttgactcgtc tcttgctcaa ggcatctgac aaggcaccat ggtcagataa cggtgacgct
     2281 aaaaacccag ccctatctcc actaggtgaa aacgtgaaga ccaaaggtca atacttctat
     2341 caagtagcct tggacggaaa tgtagctggc aaagaaaaa
//
LOCUS       DAVHTH010000115         2343 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.116, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000115 DAVHTH010000000
VERSION     DAVHTH010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2343)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2343)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2343
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.116"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            15..1076
                     /gene="dinB"
                     /locus_tag="VVR63_002087"
     CDS             15..1076
                     /gene="dinB"
                     /locus_tag="VVR63_002087"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HEU6130046.1"
                     /translation="MLIFPLLNDLSRKIIHIDMDAFFAAVEIRDNPKLRGKPVIIGSD
                     PRQTGGRGVVSTCSYEARAFGVHSAMSSKEAYERCPQAVFISGNYEKYKSVGLQIRAI
                     FKRYTDLIEPMSIDEAYLDVTENKLGIKSAVKIARLIQKDIWQELHLTASAGVSYNKF
                     LAKMASDYQKPHGLTVILPEQAEDFLKQMDISKFHGVGKKTVERLHQMGVFTGADLLE
                     VPEVTLIDRFGRLGYDLYRKARGIHNSPVKSNRIRKSIGKEKTYGKILLAEEDIKKEL
                     TLLSEKVALNLHQQEKAGKIVILKIRYEDFSTLTKRKSLAQKTQDASQISQIALQLYE
                     ELSKKERGVRLLGITMTGF"
     gene            complement(1223..2068)
                     /locus_tag="VVR63_002088"
     CDS             complement(1223..2068)
                     /locus_tag="VVR63_002088"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HEU6130047.1"
                     /translation="MYLIEILKSIFFGIVEGITEWLPISSTGHLILAEEFIQYQNQNE
                     AFMSMFNVVIQLGAILAVMVIYFNKLNPFKPTKDKQEVRKTWRLWLKVLIATLPLLGV
                     FKFDDWFDTHFHNMVSVALMLIIYGVAFIYLEKRNKARAIEPSVTELDKLPYTTAFYI
                     GLFQVLALLPGTSRSGATIVGGLLNGTSRSVVTEFTFYLGIPVMFGASALKIFKFVKA
                     GELLSFGQLFLLLVAMGVAFAVSMVAIRFLTSYVKKHDFTLFGKYRIVLGSVLLLYSF
                     VRLFV"
     gene            complement(2099..2236)
                     /locus_tag="VVR63_002089"
     CDS             complement(2099..2236)
                     /locus_tag="VVR63_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001270407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6130048.1"
                     /translation="MRYQTHYQLKQKLWLDPFGNRQAIGGNELIHSGLFQVYHLGFGS
                     S"
BASE COUNT          777 a          476 c          470 g          620 t
ORIGIN      
        1 aaaaggtgct aggcatgttg atttttcctt tgttaaatga tttgtcaaga aaaatcatcc
       61 atattgacat ggatgccttt tttgctgcag tggaaatcag ggataatcct aaactcagag
      121 gaaaacctgt cattattgga agcgaccctc ggcaaacagg tggacgggga gtcgtttcta
      181 cctgtagtta tgaggcaaga gcttttggtg tccattctgc catgagttcc aaggaagctt
      241 atgaacgttg tccccaggct gtctttatct cagggaatta tgagaaatac aagtctgtgg
      301 gactccagat tcgagctatt tttaagcgct atacagattt gattgaaccc atgagcattg
      361 acgaagccta tttggatgtg acagaaaata aactcggtat caagtcagcg gtcaaaattg
      421 ctcgcctcat tcaaaaagat atctggcaag aactccatct aactgcttcc gcaggcgttt
      481 cttacaacaa attcttagct aaaatggcga gtgattatca aaaaccacat ggtttgacag
      541 tgattctacc tgaacaggct gaggattttc tcaaacaaat ggatatttcc aaatttcatg
      601 gagtaggaaa aaagacagta gaacgtcttc atcaaatggg cgtttttact ggtgctgatt
      661 tacttgaagt tcctgaggta accctaatag accgttttgg tagactaggc tatgatctgt
      721 atcgaaaggc tcgtggcatt cacaactctc cagtcaaatc caatcgcatc cgtaaatcaa
      781 tcggcaagga gaaaacctac gggaagattc tccttgctga ggaagatatc aaaaaagagc
      841 tgactcttct atcagaaaaa gtcgctctca atctacatca acaagaaaaa gctggaaaaa
      901 ttgtcatttt gaaaatccgc tacgaggact tttcaactct taccaaacga aaaagtcttg
      961 ctcaaaaaac acaagatgct agtcagataa gccaaatagc cctgcaactc tatgaagaat
     1021 taagcaagaa agaaagaggt gtccgcctat tggggattac catgactgga ttttaaagct
     1081 caatgaaaat caaagagcaa actaggaggc tagccgcagg ctgctcaaaa cactgttttg
     1141 aggttgcaga taaagctgac gcggtttgaa gagattttcg aagagtataa aaccttgaag
     1201 agttgcccct tcaaggtttt tcttatacaa ataaacggac aaaactgtaa agtagcaaaa
     1261 cactaccaag cacgatacgg tatttaccaa aaagggtgaa gtcgtgtttt ttcacatagc
     1321 tggtcaagaa gcgaatagcc accatgctga ccgcaaaagc tactcccatc gcgaccaaga
     1381 gcaaaaacaa ttgcccaaag ctcaagagtt ctccggcttt cacaaatttg aaaatcttta
     1441 aggcactagc tccaaacata acaggaatcc caagatagaa ggtaaattct gtcacaactg
     1501 aacgactggt tccatttaac aaaccaccga caatcgttgc acctgaacgg ctagtccctg
     1561 gtaaaagagc aagaacttgg aagagtccga tatagaaagc ggtcgtataa ggaagcttgt
     1621 ccaactctgt tacacttggc tcgatagcac gcgctttatt gcgcttttcc aaatagatga
     1681 aggcaacccc gtagataatc aacatgagag caactgaaac catgttatgg aagtgggtat
     1741 caaaccaatc atcaaattta aagacaccaa gtaaaggtaa agtagcaatc aagaccttca
     1801 accatagtct ccaagtctta cgaacttcct gtttgtcctt agtcggttta aaaggattga
     1861 gcttgttaaa ataaatcacc ataactgcta aaatagcacc aagctgaatc acgacattaa
     1921 acatggacat aaaggcttca ttttgatttt ggtattggat gaattcctct gctaaaatca
     1981 agtgacctgt actggaaatc ggcaaccatt ccgtaattcc ttcaacaatc ccgaagaaga
     2041 tagattttaa aatttcaata agatacatag attactccct atattataat tagcgcagtt
     2101 agctactgcc aaagcccaag tggtatactt ggaataagcc actgtggatt agttcatttc
     2161 ctccaatcgc ttgacgattt ccgaaaggat ctaaccacag cttttgtttc aattggtaat
     2221 gagtttgata acgcatagac gttttatctc gtctaaggta acaaggcaaa aagttcgtgg
     2281 ataaccaagt agacttgaaa tactatatct ggaggtactc ccatgcttta tgtgggcatt
     2341 gat
//
LOCUS       DAVHTH010000116         2300 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.117, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000116 DAVHTH010000000
VERSION     DAVHTH010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2300)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2300)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2300
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.117"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            185..1730
                     /locus_tag="VVR63_002090"
     rRNA            185..1730
                     /locus_tag="VVR63_002090"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            1782..1854
                     /locus_tag="VVR63_002091"
     tRNA            1782..1854
                     /locus_tag="VVR63_002091"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1815..1817,aa:Ala,seq:tgc)
     gene            1979..>2300
                     /locus_tag="VVR63_002092"
     rRNA            1979..>2300
                     /locus_tag="VVR63_002092"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          646 a          465 c          681 g          508 t
ORIGIN      
        1 gttgacaagt gaaagtggct gtgatatact aatatagttg tcgcttgaga gaagcaagtg
       61 acaaagacct ttgaaaactg aacaagacga accaatgtgc agggcgctac aacataagtt
      121 gtagtactga acaatgaaaa aacaataaat ctgtcagtga cagaaatgag taagaactca
      181 aacttttaat gagagtttga tcctggctca ggacgaacgc tggcggcgtg cctaatacat
      241 gcaagtagaa cgctgaagga ggagcttgct tctctggatg agttgcgaac gggtgagtaa
      301 cgcgtaggta acctgcctgg tagcggggga taactattgg aaacgatagc taataccgca
      361 taagagtaga tgttgcatga catttgctta aaaggtgcac ttgcatcact accagatgga
      421 cctgcgttgt attagctagt tggtggggta agggctcacc aaggcgacga tacatagccg
      481 acctgagagg gtgatcggcc acactgggac tgagacacgg cccagactcc tacgggaggc
      541 agcagtaggg aatcttcggc aatggacgga agtctgaccg agcaacgccg cgtgagtgaa
      601 gaaggttttc ggatcgtaaa gctctgttgt aagagaagaa cgagtgtgag agtggaaagt
      661 tcacactgtg acggtatctt accagaaagg gacggctaac tacgtgccag cagccgcggt
      721 aatacgtagg tcccgagcgt tgtccggatt tattgggcgt aaagcgagcg caggcggtta
      781 gataagtctg aagttaaagg ctgtggctta accatagtag gctttggaaa ctgtttaact
      841 tgagtgcaag aggggagagt ggaattccat gtgtagcggt gaaatgcgta gatatatgga
      901 ggaacaccgg tggcgaaagc ggctctctgg cttgtaactg acgctgaggc tcgaaagcgt
      961 ggggagcaaa caggattaga taccctggta gtccacgctg taaacgatga gtgctaggtg
     1021 ttagaccctt tccggggttt agtgccgtag ctaacgcatt aagcactccg cctggggagt
     1081 acgaccgcaa ggttgaaact caaaggaatt gacgggggcc cgcacaagcg gtggagcatg
     1141 tggtttaatt cgaagcaacg cgaagaacct taccaggtct tgacatccct ctgaccgttc
     1201 tagagataga gttttccttc gggacagagg tgacaggtgg tgcatggttg tcgtcagctc
     1261 gtgtcgtgag atgttgggtt aagtcccgca acgagcgcaa cccctattgt tagttgccat
     1321 catttagttg ggcactctag cgagactgcc ggtaataaac cggaggaagg tggggatgac
     1381 gtcaaatcat catgcccctt atgacctggg ctacacacgt gctacaatgg ctggtacaac
     1441 gagtcgcaag ccggtgacgg caagctaatc tcttaaagcc agtctcagtt cggattgtag
     1501 gctgcaactc gcctacatga agtcggaatc gctagtaatc gcggatcagc acgccgcggt
     1561 gaatacgttc ccgggccttg tacacaccgc ccgtcacacc acgagagttt gtaacacccg
     1621 aagtcggtga ggtaaccgta aggagccagc cgcctaaggt gggatagatg attggggtga
     1681 agtcgtaaca aggtagccgt atcggaaggt gcggctggat cacctccttt ctaaggataa
     1741 ggaactgcgc attggtcttg tttagtcttg agaggtcttg tggggcctta gctcagctgg
     1801 gagagcgcct gctttgcacg caggaggtca gcggttcgat cccgctaggc tccattggtg
     1861 agagatcacc aagtaatgca cattgaaaat tgaatatcta tatcaaatag taacaagaaa
     1921 ataaaccgaa aacgctgtag tattaataag agtttatgac tgaaaggtca gaaaataagg
     1981 ttaagttaat aagggcgcac ggtggatgcc ttggcactag gagccgacga aggacgtgac
     2041 aaacgacgat atgccttggg tagctgtaag taagcgatga tccagggatt tccgaatggg
     2101 ggaacccaac aggtaatacc tgttacctac atctgttaag gatgtgagga ggaagacgca
     2161 gtgaactgaa acatctaagt agctgcagga agagaaagca aaagcgattg ccttagtagc
     2221 ggcgagcgaa acggcagaag ggcaaaccga agagtttact cttcggggtt gtaggactgc
     2281 aatgtggact caaagattat
//
LOCUS       DAVHTH010000117         2172 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.118, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000117 DAVHTH010000000
VERSION     DAVHTH010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2172)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2172)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2172
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.118"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            complement(<1..242)
                     /locus_tag="VVR63_002093"
     CDS             complement(<1..242)
                     /locus_tag="VVR63_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6130049.1"
                     /translation="MKKTLTPTKESIDSLRNYEASKQLTDTRFKRLVGVQRTTFKEML
                     AVLKTDYQLKHAKGGRKPKLSLEDLLMATLQYVREYR"
     gene            complement(187..369)
                     /locus_tag="VVR63_002094"
     CDS             complement(187..369)
                     /locus_tag="VVR63_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEU6130050.1"
                     /translation="MDLKFEGVDLEYKKAKNNLPESFWETYSAFANTNGGKIILGIDE
                     KNIDTYQRVNRLPAKL"
     gene            704..>2172
                     /gene="pcpA"
                     /locus_tag="VVR63_002095"
     CDS             704..>2172
                     /gene="pcpA"
                     /locus_tag="VVR63_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein PcpA"
                     /protein_id="HEU6130051.1"
                     /translation="MKKTTILSLTTAAVILAAYVPNEPILADTPSSEVIKETKVGSII
                     QQNNIKYKVLTVEGNIGTVQVGNGVTPVEFEAGQDGKPFTIPTKITVGDKVFTVTEVA
                     SQAFSYYPDETGRIVYYPSSITIPSSIKKIQKKGFHGSKAKTIIFDKGSQLEKIEDRA
                     FDFSELEEIELPASLEYIGTSAFSFSQKLKKLTFSSSSKLELISHEAFANLSNLEKLT
                     LPKSVKTLGSNLFRLTTSLKHVDVEEGNESFASVDGVLFSKDKTQLIYYPSQKNDESY
                     KTPKETKELASYSFNKNSYLKKLELNEGLEKIGTFAFADAIKLEEISLPNSLETIERL
                     AFYGNLELKELILPDNVKNFGKHVMNGLPKLKSLTIGNNINSLPSFFLSGVLDSLKEI
                     HIKNKSTEFSVKKDTFAIPETVKFYVTSEHIKDVLKSNLSTSNDIIVEKVDNIKQETD
                     VAKPKKNSNQGVVGWVKDKGLWYYLNESGSMATGWVKDKG"
BASE COUNT          778 a          305 c          357 g          732 t
ORIGIN      
        1 cggtattctc gcacatattg aagagtggcc ataagaaggt cttctaggct taatttaggt
       61 tttcgtccac cttttgcgtg tttaagttga taatctgttt ttaacacagc taacatctct
      121 ttaaaagtgg tacgctgaac accaacaaga cgcttaaatc gtgtatcagt taattgttta
      181 cttgcttcat aatttcgcag ggagtctatt gactctttgg taggtgtcaa tgtttttttc
      241 atctataccg agaattattt tcccgccatt tgtatttgca aatgctgagt aggtttccca
      301 gaaagactct ggaagattgt ttttagcttt tttgtattct aaatcaaccc cttcaaattt
      361 taagtccata tttttccttt acatctgttt tttgtggttc tggtatttgt tcaagttgag
      421 tgataatata gcgaattgaa tttcgagagt ttttactcag ttaatttctt ttttaacccg
      481 ctttaatttc ttttttaaca cgtgttaaaa aagaaattaa agcgggttaa tttttcttga
      541 cttaaaattt aaaaatgata tactgtgttt atggagagat gacaatttat aaaatgtact
      601 actctattct actagataat gattgaataa aactttttat aacaacggct agcaaagtta
      661 taattttata tctattagaa aataaatatg taaggaaatt taaatgaaaa aaactacaat
      721 attatcatta actacagctg cagttatttt agcagcatat gtccctaatg aaccaatcct
      781 agcagatact cctagttcgg aagtaatcaa agagactaaa gttggaagta ttattcaaca
      841 aaataatatc aaatataagg ttctaactgt agaaggtaac ataggcactg ttcaagtggg
      901 taatggagtt actcctgtag agtttgaagc tggtcaagat ggaaaaccat tcacgattcc
      961 tacaaaaatc acagtaggtg ataaagtatt taccgttact gaagtagcta gtcaagcttt
     1021 tagttattat ccagatgaaa caggtagaat tgtctactat cctagctcta ttactatccc
     1081 atcaagcata aaaaaaatac aaaaaaaagg cttccatgga agtaaagcta aaactattat
     1141 ttttgacaaa ggtagtcagc tggagaaaat tgaagataga gcttttgatt tttctgaatt
     1201 agaagagatt gaattgcctg catctctaga atatattgga acaagtgcat tttcttttag
     1261 tcaaaaattg aaaaagctaa ccttttcctc aagttcaaaa ttagaattaa tatcacatga
     1321 ggcttttgct aatttatcaa atttagagaa actaacatta ccaaaatcgg ttaaaacatt
     1381 aggaagtaat ctatttagac tcactactag cttaaaacat gttgatgttg aagaaggaaa
     1441 tgaatcgttt gcctcagttg atggtgtttt gttttcaaaa gataaaaccc aattaattta
     1501 ttatccaagt caaaaaaatg acgaaagtta taaaacgcct aaggagacaa aagaacttgc
     1561 atcatattcg tttaataaaa attcttactt gaaaaaactc gaattgaatg aaggtttaga
     1621 aaaaattggt acttttgcat ttgcagatgc gattaaactt gaagaaatta gcttaccaaa
     1681 tagtttagaa actattgaac gtttagcctt ttacggtaat ttagaattaa aagaacttat
     1741 attaccagat aatgttaaaa attttggtaa acacgttatg aacggtttac caaaattaaa
     1801 aagtttaaca attggtaata atatcaactc attgccgtcc ttcttcctaa gtggcgtctt
     1861 agattcatta aaggaaattc atattaagaa taaaagtaca gagttttctg tgaaaaaaga
     1921 tacatttgca attcctgaaa ctgttaagtt ctatgtaaca tcagaacata taaaagatgt
     1981 tcttaaatca aatttatcta ctagtaatga tatcattgtt gaaaaagtag ataatataaa
     2041 acaagaaact gatgtagcta aacctaaaaa gaattctaat cagggagtag ttggttgggt
     2101 taaagacaaa ggtttatggt attacttaaa cgaatcaggt tcaatggcta ctggttgggt
     2161 taaagacaaa gg
//
LOCUS       DAVHTH010000118         2127 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.119, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000118 DAVHTH010000000
VERSION     DAVHTH010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2127)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2127)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2127
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.119"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            complement(<1..1732)
                     /gene="patB"
                     /locus_tag="VVR63_002096"
     CDS             complement(<1..1732)
                     /gene="patB"
                     /locus_tag="VVR63_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatB"
                     /protein_id="HEU6130052.1"
                     /translation="MKTVQFFWHYFKVYKFSFVVVILMIVLATFAQALFPVFSGQAVT
                     QLANLVQAYQNGNPELVWQSLSGIMVNLGLLVLVLFISSVIYMCLMTRVIAESTNEMR
                     KGLFGKLAQLTVSFFDRRQDGDILSHFTSDLDNILQAFNESLIQVMSNIVLYIGLILV
                     MFSRNVTLALITIASTPLAFLMLIFIVKMARKYTNLQQKEVGKLNAYMDESISGQKAV
                     IVQGIQEDMMAGFLEQNERVRKATFKGRMFSGILFPVMNGMSLINTAIVIFAGSAVLL
                     NDKSIETSTALGLIVMFAQFSQQYYQPIIQVAASWGSLQLAFTGAERIQEMFDAEEEI
                     RPEKAPTFTKLQESVEISHIDFSYLPDKPILKDVSISAPKGQMTAVVGPTGSGKTTIM
                     NLINRFYDVDAGGIYFDGKDIRGYDLDSLRSKVGIVLQDSVLFSGTIRDNIRFGVPDA
                     NQEMVEVAAKATHIHDYIESLPDKYDTLIDDDQSIFSTGQKQLISIARTLMTDPEVLI
                     LDEATSNVDTVTESKIQHAMEVVVAGRTSFVIAHRLKTILNADQIIVLKDGEVIERGN
                     HHELLKLGGFY"
     gene            1930..2127
                     /locus_tag="VVR63_002097"
                     /pseudo
     CDS             1930..2127
                     /locus_tag="VVR63_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844241.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          628 a          468 c          422 g          609 t
ORIGIN      
        1 aataaaagcc acctagcttc aaaagttcat ggtggttacc acgttcaatg acttctccat
       61 ctttaaggac aataatctga tctgcattga gaatggtttt caagcggtgg gcaatgacga
      121 aactagttct acctgctaca accacctcca tggcatgctg aatcttgctt tccgtcaccg
      181 tatctacgtt tgaagttgct tcatcgagaa tgagaacttc tggatctgtc atcagggttc
      241 gagcgattga aatcaattgc ttctgccctg ttgaaaagat gctctggtca tcatcaataa
      301 gagtatcgta cttatcaggc aaactttcga tatagtcgtg aatgtgggtt gcttttgctg
      361 ctacctcaac catttcctga ttagcatctg gcacaccaaa tcggatattg tctcgaatcg
      421 ttccgctaaa caagaccgaa tcttgcaata caattcccac cttgcttcta agactatcta
      481 agtcatagcc acgaatgtct ttaccatcaa aataaatacc accagcatca acatcataaa
      541 agcgattgat gaggttcata atagtcgttt ttcctgaacc tgtaggccca acaactgctg
      601 tcatctggcc tttaggggca gaaatgctga catctttcaa aataggttta tcaggcaagt
      661 atgaaaaatc gatatgactg atttcaacac tttcttgcaa cttagtgaag gttggagcct
      721 tttcaggtcg gatttcctcc tctgcatcaa acatttcctg aattcgttca gctccagtaa
      781 aggccaactg aaggcttccc caactcgctg caacttggat aataggctgg tagtactgct
      841 gtgaaaattg tgcaaacata acaatcaaac ctagggctgt acttgtttca atagacttat
      901 cattcaaaag tacagccgaa ccagcaaaga tgacgatggc tgtattaatc aggctcatcc
      961 cattcatgac agggaaaaga attcctgaga acattcttcc tttaaaggtt gccttgcgca
     1021 cgcgctcatt ttgttcaaga aatcctgcca tcatatcctc ttgaattcct tgcacaatca
     1081 cggctttttg gcctgagatg ctctcatcca tataggcgtt gagcttccct acctctttct
     1141 gctggaggtt ggtgtattta cgtgccattt tcacgatgaa aatcagcata aggaaagcca
     1201 atggggtgct ggcaatggtg atgagagcca gcgtcacatt tctcgaaaac atgacaagaa
     1261 tcagaccaat gtataaaaca atattgctca tgacctgaat caagctttcg ttaaaggctt
     1321 ggaggatatt atccaaatca ctggtaaaat gagacaggat atcgccatct tgtcgacggt
     1381 caaagaaaga aaccgtcaac tgagcaagct taccaaagag gcctttgcgc atctcgttgg
     1441 tcgattctgc aatcacgcgc gtcatgagac acatgtatat tacactagag ataaatagaa
     1501 ccaaaaccag caggccaaga ttgaccatga ttcctgatag gctttgccat acaagttctg
     1561 gattgccatt ttgataagct tgaactaaat tggctagctg cgtcaccgct tgtccagaaa
     1621 agactggaaa gagggcttgg gcaaaagtcg ccagaacaat catcaggatg acaactacaa
     1681 atgagaactt gtagacctta aaataatgcc aaaaaaattg aactgtcttc attttactcc
     1741 tccttatatt atatttagcg cagttagcta ctgccaaagc ccaagtggta tacttggaat
     1801 aagccgctgt ggattagttc atttcctcca atcgcttgac aatttccgaa aggatctaac
     1861 cacagctttt tgtttcaatt ggtaatgagt ttgataacgc ataaacgttt tatctcttgt
     1921 aatgaaaaca tcaaacatta caagaggctc attgacaagg cgaaaaaatg tgtcaatgac
     1981 ttgatggctg agttcaactc ggtcatcacg acggttactg ggattgagaa tcgtttaggg
     2041 gcggtcattt tagccgagat tcgaaatatt catgcctttg ataatcctgc tcaattacaa
     2101 gctttcgctg gactggattc ttctatt
//
LOCUS       DAVHTH010000119         2065 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.120, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000119 DAVHTH010000000
VERSION     DAVHTH010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2065)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2065)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2065
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.120"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            <1..874
                     /locus_tag="VVR63_002098"
     CDS             <1..874
                     /locus_tag="VVR63_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HEU6130053.1"
                     /translation="YLHKVDSLIDYFESFVIIPNITIHDLSNVVSESYHKGESIEELA
                     LYAREKLGISKDNHDLLYKLERSGIYIVERLINGQADAYSAWSKLGRPYIVLGTNKSS
                     VRRNFDLAHELGHILLHKYKDMNEDGDRLEQEANYFASCFLLPKEEFLVKFEERVGKR
                     VSNPDSYILLKSDLNVSIQALEYRAFKLGLLTPKQHSYFYRQIAQKGYKMIEPLDDQI
                     FVKKPSKVKSILDVVLSNHLVSLATIMSKQSIRLQFISEIFSVEMKFFDQYQEDRRTD
                     RFDNIIPLYKRNNL"
     gene            complement(926..1585)
                     /locus_tag="VVR63_002099"
     CDS             complement(926..1585)
                     /locus_tag="VVR63_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HEU6130054.1"
                     /translation="MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTRLR
                     PLDLIPILSQVFNRFCCRYCKVRYPVWYALFELGLGLLFLLYSWELLSLSQVILITAA
                     LTLGIYDFRHQEYPLLVWMTFHLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
                     FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLAACVIIFGKLLL
                     V"
     gene            1655..2062
                     /locus_tag="VVR63_002100"
     CDS             1655..2062
                     /locus_tag="VVR63_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000155434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6130055.1"
                     /translation="MTIRFEEKVSTENAQFVCQWSNSLGKVFQEQWIGPRIPFPLTIQ
                     VFQDLEGILSIFEGQEFVGLIQKIRLEDSNLHIGRFFINPQKQGQGLGSQALRKFVSL
                     AFENRDIDSISLNVFEANQRAQNLYQKEGFEIV"
BASE COUNT          743 a          319 c          445 g          558 t
ORIGIN      
        1 gtatttacat aaggtagata gtttgattga ttattttgaa agttttgtaa ttatacctaa
       61 tattacaatt catgacttaa gtaatgtagt gagtgaatct tatcataagg gagaatccat
      121 tgaggaattg gctctttatg ccagggaaaa attaggtatt tcaaaagata atcatgattt
      181 gctttataaa ttagaacgtt caggcatcta tatcgtggaa cgattaatta atggccaagc
      241 tgatgcttat agcgcatggt caaaattggg aagaccttat attgtgttgg gaacgaataa
      301 atcatctgta cgtcgaaatt ttgacttagc tcatgagcta ggacatattc ttttacataa
      361 atataaagat atgaatgaag atggcgatcg tttggagcaa gaagcaaatt attttgcatc
      421 atgtttttta ttgccaaaag aagagttttt agtcaaattt gaagagaggg ttggcaagcg
      481 tgtcagcaat cctgatagtt atattttatt gaagtcggat ttgaatgttt cgatacaggc
      541 tttagagtat cgagctttta agttaggatt attgactcca aagcaacatt cttactttta
      601 tcgtcaaatt gcgcaaaaag gttacaaaat gattgaacct ttggatgatc aaatttttgt
      661 taaaaaacca agcaaagtaa agagtattct ggacgtcgtt ttgagtaatc atctagtcag
      721 tctagcgact ataatgtcta aacaaagtat tcgtttacag tttataagcg aaatattttc
      781 agtcgaaatg aaattttttg atcagtatca agaagataga agaacagatc gatttgataa
      841 catcatccct ttgtacaaaa gaaataattt ataatttaac tgtgaaataa tttcatgaag
      901 gacatatggc agaaattgga ttttatcaga caagcagtag cttaccaaaa ataatcacac
      961 aagcagcaag taagaggaaa ggcacgaaag gaagtctttc ctttttcttt tgcaggagaa
     1021 aggccaggat acccgtcgca gaagcgaact gaatcaagat cagtaactcc gttacgctaa
     1081 agacgagagc gcaagaagct aaaaaaagaa aatcccctgc acccatgcgg atatcgataa
     1141 aatgagccaa aattccaagt atgaggaagg agaccatgac cagattccag ccagaggaag
     1201 ctattaggat taggtggaaa gtcatccaga ccagtaaggg atattcctga tggcgaaagt
     1261 cgtagatacc caaggtcaaa gcagcagtga ttaggatgac ttgactcaag gaaagtaatt
     1321 cccaagagta aagcagaaag aggagtccta agcctagttc aaagagggca taccagacag
     1381 gatagcggac cttgcagtag cgacagcaaa agcgattgaa gacctgtgag agaatcggaa
     1441 tcaaatctaa gggacgcaag cgagtctgac aggaatcgca gtgactggct gaactgataa
     1501 tggattgctc tggaaaacgg tcaatgacca aaccaagaaa ggaagcgaga atgctcccga
     1561 cgagaaaaaa ataaaaatca atcatactta tctattcgta aaaaatggga gaaatagtat
     1621 aatggagaaa catagataag gtggtgagga aaagatgaca attcgttttg aagaaaaggt
     1681 gagcacagaa aacgctcaat ttgtatgcca gtggtccaac tccctaggca aagtctttca
     1741 agaacaatgg ataggaccaa ggattccttt tcccctgaca attcaagtct ttcaagattt
     1801 ggaaggaatc ctttcaatct ttgaaggaca agagtttgtc ggtcttatcc agaaaattag
     1861 gctagaagac agtaatcttc atattggaag attctttatc aacccccaga aacaggggca
     1921 aggcttaggt agccaggctt taaggaaatt tgttagttta gcatttgaaa atagagatat
     1981 agacagtatt tctctaaatg tcttcgaggc aaatcaaaga gctcagaatc tttaccaaaa
     2041 agaaggattt gaaatcgttt aaatg
//
LOCUS       DAVHTH010000120         2055 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.121, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000120 DAVHTH010000000
VERSION     DAVHTH010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2055)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2055)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2055
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.121"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            272..1618
                     /gene="gdhA"
                     /locus_tag="VVR63_002101"
     CDS             272..1618
                     /gene="gdhA"
                     /locus_tag="VVR63_002101"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HEU6130056.1"
                     /translation="MTSAKEYIQSVFETVKARNGHEAEFLQAVEEFFNTLEPVFEKHP
                     EYIEENILARITEPERVVSFRVPWVDRDGKIQVNRGYRVQFNSAVGPYKGGLRFHPTV
                     NQGILKFLGFEQIFKNVLTGLPIGGGKGGSDFDPKGKTDAEVMRFCQSFMTELQKHIG
                     PSLDVPAGDIGVGGREIGYLYGQYKRLNQFDAGVLTGKPLGFGGSLIRPEATGYGLVY
                     YTEEMLKANGNSFAGKKVVISGSGNVAQYALQKATELGATVISVSDSNGYVIDENGID
                     FDLLVDVKEKRRARLTEYAAEKATATYHEGTVWTYAGNYDIALPCATQNEINGEAAKR
                     LVAQGVICVSEGANMPSDLDAIKVYKENGIFYGPAKAANAGGVAVSALEMSQNSLRLS
                     WTREEVDGRLKDIMTNIFNTAKTTSETYGLDKDYLAGANIAAFENVANAMIAQGIV"
BASE COUNT          660 a          373 c          395 g          627 t
ORIGIN      
        1 atagttttac tggcaaatct aacatatcac ggataaatta acaagtgatt tctgaattgc
       61 taaacatttt cttttcttat agcatacttt aagattttgt ctttgagaaa gatatttcca
      121 agaaaaacgt tcgttttttt atctattttc aaaaaaacca aaaaactgaa ttgaaagaat
      181 ttttagaaaa tttctgtttt ttctttacag tgaaaaaaaa ttctgctata atgtcttatg
      241 taataaaata tgacaataaa aggagaacga tatgacatct gctaaagaat atatccaaag
      301 cgtgtttgaa actgtgaaag ctcgtaacgg gcacgaggct gaattcctcc aagctgttga
      361 agaatttttc aacactttag aacctgtatt tgaaaaacac cctgagtata tcgaagaaaa
      421 tatcttggca cgtattactg agcctgagcg cgtggtttct ttccgtgttc cttgggttga
      481 ccgtgatgga aaaattcaag taaaccgtgg ttaccgtgtt caattcaact cagctgttgg
      541 accatacaaa ggtggacttc gtttccaccc aactgtaaac caagggatct tgaaattcct
      601 cggatttgaa caaatcttta aaaatgtctt gactggactt cctatcggtg gaggtaaagg
      661 tggatcagac ttcgatccta aaggtaaaac agatgctgaa gtgatgcgct tctgccaaag
      721 cttcatgact gaattgcaaa aacacatcgg accatcactt gacgtacctg ctggtgatat
      781 cggtgttggt ggacgtgaaa ttggttacct ttacggtcaa tacaaacgtc ttaaccaatt
      841 tgatgctggt gtcttgactg gtaaacctct tggatttggt ggtagcttga ttcgtccaga
      901 agcaactggt tacggtttgg tttactatac tgaagaaatg ctcaaagcta acggtaacag
      961 ctttgctggt aagaaagtcg ttatttcagg ttctggtaac gttgctcaat atgctcttca
     1021 aaaagcaact gaactcggtg caactgttat ttctgtttct gactcaaatg gttatgtcat
     1081 cgatgaaaat ggtatcgact tcgatctttt ggttgatgtt aaagaaaaac gtcgtgctcg
     1141 tttgactgag tatgcagctg aaaaagcaac tgcaacctac cacgaaggta ctgtatggac
     1201 ttacgctgga aactatgaca ttgctcttcc atgtgccact caaaacgaaa tcaacggtga
     1261 agcagctaaa cgtttggttg ctcaaggcgt tatctgtgta tctgaaggtg ccaacatgcc
     1321 gagcgacctt gatgccatca aagtttacaa agaaaatggt atcttctacg gacctgcaaa
     1381 agctgccaac gctggtggtg tagccgtttc agctcttgaa atgagccaaa acagtcttcg
     1441 cctctcatgg actcgtgaag aagttgatgg ccgtctcaaa gacatcatga caaacatctt
     1501 caacacagct aaaacgactt cagaaacata cggtcttgat aaagactacc ttgcaggagc
     1561 taacattgct gcctttgaaa atgtagcaaa tgccatgatt gcacaaggta ttgtttaaga
     1621 tttatttact caatcctcaa tcactacgat tggggatttt tagcttgaat taaaaaattg
     1681 gaaaatctaa ttaaataaaa tgaaatgaaa taaaaactga acaaattgat tgcggaattc
     1741 aaaccaattt ctaacatact tctagaaatt aatttgactt ttctaatcga tttgttcata
     1801 tcttatttca atttactata cttacttaac cctttttata ctcaatgaaa atcaaagagc
     1861 aaactaggaa gcgagccgca ggctgtactt gagtacggca aggcaaagct gacgtggttt
     1921 gaagagattt tcaaagagta ttaaacaaaa agaaaaaccg ctactcctaa gaatagcgat
     1981 ttaatcatgt ttttaagcta ctactgtagt tgctctatta tttaagtgtt atgaataact
     2041 tcaatatctt taaag
//
LOCUS       DAVHTH010000121         1916 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.122, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000121 DAVHTH010000000
VERSION     DAVHTH010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1916)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1916)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1916
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.122"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            <1..514
                     /locus_tag="VVR63_002102"
     CDS             <1..514
                     /locus_tag="VVR63_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000356590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU6130057.1"
                     /translation="KIRNAKLSSIRRNEVSFIFQAYNLIPSLPVIENIALPLRLSQKK
                     LTIKNVENLLKRMKFNAGLNDFVGTLSGGEQQKVAIARAVIADSDIIFADEPTGALDS
                     VSREVIFELLRELVGAGKCVIMVTHDIELASKTDRALILKDGKIFKELHRPSGEELYK
                     ILEVQSTTEE"
     gene            517..1836
                     /locus_tag="VVR63_002103"
     CDS             517..1836
                     /locus_tag="VVR63_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6130058.1"
                     /translation="MLRLVYYQFLHNKKQWLGVSPVIFVSSLVMGLAVNGVINVENNS
                     QVFVGLPDPKPIFMFPIVFGGVTLFFVLSNIINMLVEIFRDDYELLEVLGASLLQLSF
                     LVGGQIFIISSIISFIAYLCSIFVTSNYYYFLQYFFGENILPDIQFQTSAVGCIITVV
                     LISFLAFLSGCFYTFKKIRNRKSSKIRHVLSIVKRILLLAGFSVIWLLSLQQIFQDST
                     ILAKAQIIFNIVILDIVIIYQLSPFIQSCFIKLLSIIIFRNNFMFIVSKWNLLYRKPY
                     IKSISAAITGAILLISSFQMISQNILSQFQDDSDLELKVAFIVYVGAPILIVLANIIS
                     IAFLSSHQERIEIQQFEILGTSNYQMVKIKVGEAIFLTFVTSLIAFLLNIKIMALIYY
                     SLEDILIDDMNLLGLILPNFIVSIILFILIFITKSSYFIFKNAKIIS"
BASE COUNT          613 a          244 c          334 g          725 t
ORIGIN      
        1 taaaatcaga aatgcaaaat tgtcaagtat aagacgtaac gaagtatctt ttatatttca
       61 agcatacaat ttaatacctt ccctgccggt aatagaaaat atagcacttc ctttgcgatt
      121 atcacaaaaa aaattaacta ttaaaaatgt agaaaactta ctcaaaagaa tgaagtttaa
      181 tgctggctta aacgattttg ttggaactct gtctggtgga gaacaacaga aggttgctat
      241 agctagagcg gttattgctg atagtgatat aatatttgct gatgagccaa ctggggcttt
      301 agacagcgtt tctcgtgaag taatttttga attattgaga gagttagtag gggcgggtaa
      361 gtgtgtaatt atggtaacgc acgatataga attggcctcg aaaactgatc gtgcattaat
      421 attgaaagat ggaaaaattt tcaaagaact tcatagacct agcggggaag agttgtataa
      481 aatcttagag gtacaatcaa ctacggagga atagagatgc tcagattagt ttactatcaa
      541 tttttacata ataagaaaca atggttaggc gtttcaccag taatttttgt ttcgagttta
      601 gttatgggat tggctgttaa tggggtaatt aatgttgaga ataattcgca agtatttgtc
      661 ggacttccag atcctaaacc aatttttatg tttccgatag tattcggagg agtaacatta
      721 ttctttgtgc tctctaacat aataaatatg ttggttgaaa tttttagaga tgattacgaa
      781 cttctggagg tgttgggagc aagtctcctt caactatcat ttcttgtggg gggacagatt
      841 tttatcattt cctcgattat tagttttatt gcatatctat gctctatatt tgttacgtca
      901 aattattatt attttttaca atactttttc ggggaaaata tattacctga tatccaattt
      961 caaacgagtg ctgttggatg tatcattaca gtagtgttga tttcattttt agcctttcta
     1021 agtggttgct tttatacgtt caagaagatt agaaatagga agagttctaa aataaggcat
     1081 gttctttcaa tagtaaaaag aatactgcta ttggctggtt ttagtgttat ctggttgctt
     1141 tctttgcaac aaattttcca agatagcaca attttagcga aggcccagat aatattcaat
     1201 attgtaatct tagatattgt gattatttat caattatctc cttttataca gtcatgtttt
     1261 atcaaactac tttctataat tatatttaga aataatttta tgttcattgt ttcgaagtgg
     1321 aatttactat atcgtaagcc ttatataaaa tctatcagtg ctgcaattac aggagctata
     1381 ttactaattt ctagttttca aatgatttct cagaatatac tatctcaatt tcaagatgac
     1441 agtgatttag agctaaaagt ggcatttatt gtctatgtag gagcaccaat tttgatagta
     1501 cttgcaaata ttatttcaat tgcatttttg tcatcgcatc aagaaaggat tgagattcag
     1561 caatttgaaa ttttaggaac ttctaattac cagatggtta agattaaagt tggtgaggct
     1621 atatttttga catttgttac ttcattaatt gcatttttac ttaacattaa aattatggct
     1681 ttaatatact actctttaga ggatatttta atagatgata tgaatctttt ggggttaata
     1741 cttccaaatt ttatagtgtc tattatttta tttattttaa tatttattac taaaagttcc
     1801 tattttatct ttaagaatgc aaaaattatt tcttaaaaat ttgtaagttt tcgctatata
     1861 aaatagttaa atctattttg tatcattgct tgcattttac tggtggagag aatata
//
LOCUS       DAVHTH010000122         1749 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.124, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000122 DAVHTH010000000
VERSION     DAVHTH010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1749)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1749)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1749
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.124"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            <1..123
                     /locus_tag="VVR63_002104"
     CDS             <1..123
                     /locus_tag="VVR63_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HEU6130059.1"
                     /translation="LGFEPGIPVIEAGPILFRIPAMSAPVFDNIEAAIKEHGLS"
     gene            171..1646
                     /locus_tag="VVR63_002105"
     CDS             171..1646
                     /locus_tag="VVR63_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HEU6130060.1"
                     /translation="MDAIFDLIGKVFNPILEMGGPVIMLIILTVLALLFGVKFSKALE
                     GGIKLAIALTGIGAIIGMLNGAFSASLAKFVENTGIQLSITDVGWAPLATITWGSAWT
                     LYFLLIMLIVNVVMLAMKKTDTLDVDIFDIWHLSITGLLIKWYADNNGVSQGVSLFIA
                     TAAIVLVGVLKIINSDLMKPTFDDLLNAPSSSPMTSTHMNYMMNPVIMVLDKIFEKFF
                     PGLDKYDFDAAKLNKKIGFWGSKFFIGFILGIVIGIMGTPHPIAGVADADKWRLVIKG
                     WLSLGLTAGVSLELFSLIGSWFIAAVEPLSQGITNVATKRLRGRKFNIGLDWPFIAGR
                     AEIWACANVLAPIMLIEAVLLSKVGNGILPLAGIIAMGVTPALLVVTRGKLLRMIIFG
                     TLLLPLFLLSGTLIAPFATELAKGVGAFPEGVSQTQLITHSTLEGPIEKLLGWTIGNT
                     TTGDIKAILGAVVFLVFYIGIFAWYRKQMIKRNEEYAAKAK"
BASE COUNT          488 a          355 c          356 g          550 t
ORIGIN      
        1 cttggttttg aaccaggtat cccagttatc gaagctgggc caatcttatt ccgtatccca
       61 gcaatgagcg ctccagtatt tgacaatatt gaagcagcta ttaaagaaca tggattaagc
      121 taattctaat ttgttaacat tcatataaca taaaaaaggg aggaactgtt atggatgcaa
      181 tctttgacct aatcggaaag gttttcaatc ccatcttaga aatgggtgga cctgtcatca
      241 tgttgatcat tttgacagta ttggctttac tttttggagt gaaattctcc aaagcgcttg
      301 aaggtggtat caaacttgcc atcgctctta caggtatcgg tgctatcatc ggtatgctaa
      361 atggtgcttt ctcagcatca cttgcaaaat tcgttgaaaa cactggtatc caattgagta
      421 ttacagacgt tggttgggca ccactcgcaa caatcacttg gggttctgct tggacactat
      481 acttcttgct catcatgttg attgtcaacg tagtgatgct tgctatgaag aaaaccgata
      541 cacttgatgt cgatatcttt gatatctggc acttgtctat cacaggtctc ttgattaaat
      601 ggtatgctga taacaatggt gtgagtcaag gggtttcact ctttattgct acagcagcta
      661 tcgtccttgt cggtgtgttg aaaattatca actctgactt gatgaaacct acatttgatg
      721 accttcttaa cgccccaagt tcatcaccaa tgacatcaac tcacatgaac tacatgatga
      781 acccagttat catggttttg gataagattt ttgaaaaatt cttcccaggc cttgataaat
      841 atgactttga tgctgctaaa ttgaacaaga aaatcggttt ctggggatct aaattcttca
      901 tcggtttcat ccttggtatc gttatcggta ttatgggaac tccacatcca attgcaggtg
      961 ttgcagatgc agataaatgg cgtcttgtta tcaaaggatg gttgtctctt ggtttgactg
     1021 ccggtgtatc tttggaactc ttctcactta tcggttcatg gttcatcgca gccgtagaac
     1081 cactatcaca aggtattaca aacgttgcta ctaaacgtct tcgaggacgt aaattcaata
     1141 tcggtcttga ctggccattc atcgctggtc gtgctgaaat ctgggcttgt gccaacgtac
     1201 ttgcaccaat catgttgatt gaagcagtgc ttctttcaaa agttggaaat ggtatcttgc
     1261 cacttgcagg tatcatcgct atgggtgtta ctccagctct cttggttgta actcgtggta
     1321 aattgctccg tatgattatc ttcggaacac tcttgttgcc actcttcctt ctttcaggta
     1381 cacttattgc accatttgca acagaacttg ctaaaggtgt aggtgccttc ccagaaggtg
     1441 tgagccaaac tcaattgatt actcactcta ctcttgaagg accaatcgaa aaacttcttg
     1501 gttggacaat tggtaacact acaactggtg atatcaaagc aatccttggt gcagtagtct
     1561 tccttgtatt ctatatcggt atctttgctt ggtacagaaa acaaatgatc aaacgtaacg
     1621 aagagtacgc agcaaaagca aaataatgcg ctcctataaa atataaactc aatgaaaatc
     1681 aaagagcaaa ctaggaaact agccgcaggt tgctaaaaac acagttttga ggttgtagat
     1741 aagactgac
//
LOCUS       DAVHTH010000123         1630 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.125, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000123 DAVHTH010000000
VERSION     DAVHTH010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1630)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1630)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1630
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.125"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            33..484
                     /locus_tag="VVR63_002106"
                     /pseudo
     CDS             33..484
                     /locus_tag="VVR63_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013080.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
     gene            649..948
                     /locus_tag="VVR63_002107"
     CDS             649..948
                     /locus_tag="VVR63_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HEU6130061.1"
                     /translation="MKLINTTNSHSQLVKSQLESTDATLVEVYSAGNTDVIFTQAPLH
                     YEILISNKHRAIREPEIETIQEFFLKRKIDKASVDEANIKTLYSEKLIGISIPIK"
     gene            1209..1532
                     /gene="tnpB"
                     /locus_tag="VVR63_002108"
     CDS             1209..1532
                     /gene="tnpB"
                     /locus_tag="VVR63_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HEU6130062.1"
                     /translation="MMIQLSDLGQVHLVCGKTDMIQGIDSLAYLVKTHFELDPFSGQV
                     FLFCGGRKDRFKALYWDGQGFWILYKRFENGKLTWPSTEKDVKALAPEQVDWLMKGFS
                     ITPQI"
BASE COUNT          551 a          322 c          287 g          470 t
ORIGIN      
        1 taataacgat actagataat gaggaaaatg caatggcaaa cccaactttc ggagaaaaaa
       61 agtgaataca gactatattg ctcgctatgg cgtatatgca gttatcccta atcctgaaca
      121 aaaacaaatt gttcttgttc aagaaccaaa tggtgcttgg ttcctaccat gtggaaaaat
      181 tgaagcaggt gaaaatcatc aggaagccct aaagcgtgag ttgattgaag agcttggttt
      241 cacagcagaa attggtacct attacggaca agctgacgaa tatttctatt ctcgtcatcg
      301 tgatacctac tactacaatc ctgcctacct ctatgaagca actcctttca aagaagtaca
      361 aaagccacta gaaaacttta atcatattgc ctggttccct attgacgagg ctatcaaaaa
      421 ccttaaacgt ggtagccata aatgggccat tgaatcttgg aaaaaacagc ataagattgg
      481 ctaatactct tcgaaaataa aattcaaatc acgtaagcgt cgccttaccg tactcaagta
      541 tagcctgcgg ctagcttcct agtttgctct tttattttca ttgagtataa atcaagcgac
      601 tttattcaaa aagtgctata atagaattag aaaatcggag gaaatattat gaagcttatc
      661 aatacgacaa actcacactc gcaacttgta aaaagtcagc tagaaagtac cgatgcaacc
      721 cttgttgagg tttattctgc agggaataca gatgttattt ttacccaagc tccgcttcac
      781 tatgaaatcc tcatctcaaa caaacaccgt gctattcgtg agcctgaaat cgaaaccatt
      841 caagaatttt tcttgaaacg taaaattgat aaggcctctg ttgatgaagc caatatcaag
      901 acactctact cagagaaatt aattggaatt tcaatcccaa tcaagtaaga aaattgagta
      961 aaaactcgat ttgagagaaa gtccaataag tctttccata ataaaacgca tagtagcaag
     1021 agtttctaca cccactatta tacgttttta tcattttgaa atctgctgct aatcaatgaa
     1081 gaagcaaaga tcaaactagg cagctagtta caagttacgt aagcgcgtca taacaaggta
     1141 tctatcctaa ttccccaact tccagtatac tagataaaaa ataattatcg gaggaaaagt
     1201 attgtactat gatgattcaa ctaagtgatt taggtcaagt tcaccttgtt tgtggcaaga
     1261 cagatatgat acaaggaatc gattcactgg cttatctcgt taaaacccac tttgaattgg
     1321 atcctttctc cggtcaagtc tttctctttt gtggtggacg taaagaccgc tttaaagccc
     1381 tttactggga tggtcaagga ttttggatac tatataaacg ctttgagaac ggaaaactga
     1441 cttggcccag tacagaaaag gatgtcaaag ctctcgcacc tgaacaagta gactggctta
     1501 tgaagggctt ttctatcact ccccaaatat agtggattta aactagaata gtacacccct
     1561 acttctaaaa cattgttaga aatcgatttg actgtcctga tcaatttgtc ctgttcttgt
     1621 ttcattttac
//
LOCUS       DAVHTH010000124         1615 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.126, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000124 DAVHTH010000000
VERSION     DAVHTH010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1615)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1615)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1615
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.126"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            complement(242..1006)
                     /locus_tag="VVR63_002109"
     CDS             complement(242..1006)
                     /locus_tag="VVR63_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HEU6130063.1"
                     /translation="MIQKHAIPILEFDDNPQAVIMPNHEGLDLQLPKKCVYAFLGEEI
                     DRYAREVGANCVGEFVSATKTYPVYVINYKGEEVCLAQAPVGSAPAAQFMDWLIGYGV
                     EQIISTGTCGVLADIEENAFLVPVRALRDEGASYHYVAPCRYMEMQPEAIAAIEEVLE
                     DRGIPYEEVMTWTTDGFYRETAEKVAYRKEEGCAVVEMECSALAAVAQLRGVLWGELL
                     FTADSLADLDQYDSRDWGSEAFNKALELSLASVHHL"
     gene            1076..1237
                     /locus_tag="VVR63_002110"
     CDS             1076..1237
                     /locus_tag="VVR63_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(FAD)-dependent dehydrogenase"
                     /protein_id="HEU6130064.1"
                     /translation="MDKKQAYIVSCHSGLRSYIAEPILKQAGFTAQNLDGAYSLYKMV
                     NPEGVEYGN"
     gene            1227..1523
                     /locus_tag="VVR63_002111"
     CDS             1227..1523
                     /locus_tag="VVR63_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000450185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEU6130065.1"
                     /translation="METSISMADFYGKYQNENLELIDVREAHEFQAGHAPGAKNLPLS
                     TLEQGYKELKPDHEYYVICQGGVRSASTCQFLSSQGLTVTNVEGGMNAWPGQVE"
BASE COUNT          511 a          406 c          308 g          390 t
ORIGIN      
        1 gaagctgacc tggtttgaag agattttcga agagtatcat ttcatctcac tctaaatctt
       61 accaacataa aacgcatagt atcaaaattt tcatcacctg atatgatacg tttttctgat
      121 tttaaagatt tttcccaacc tcaacatgcc taggacaaga ggaaggtgac ctcgtttaaa
      181 catatttttg aaaagtatga gctagatatt ttatgataaa acaaatcctt tgccagtaca
      241 actaaaggtg gtgaacactt gctaaactca gttctagcgc cttattaaaa gcttccgagc
      301 cccagtcacg actgtcgtac tggtccaagt ccgctagaga atctgctgtg aacaacaatt
      361 caccccagag aaccccacgc aattgagcta ctgccgcaag agcagaacac tccatctcca
      421 caacagcaca gccttcttcc ttacgataag ccaccttttc agccgtttct cggtaaaaac
      481 cgtctgtcgt ccaggtcatg acttcttcat aaggaatccc tctgtcttcc aaaacttcct
      541 caatagcagc aatagcctct ggctgcattt ccatataacg acaaggtgcc acatagtggt
      601 aactggctcc ctcatctcgc aaagcgcgaa cagggactag aaaggcattt tcctctatat
      661 cagctaggac accacaggtc ccagtagaga taatctgctc cacaccatag ccaatcaacc
      721 aatccataaa ctgggctgct ggagcggagc caacaggagc ctgagccaga cagacctcct
      781 cacccttgta gttgataaca tagactggat aggtcttggt agcagaaacg aattcgccaa
      841 cacagttcgc ccctacttcc ctcgcatagc ggtcaatctc ctcacctaaa aaagcataga
      901 cacacttctt tggcaactgc aaatccaacc cctcgtgatt gggcatgata accgcctgag
      961 gattatcatc aaactctaaa atgggaatcg catgtttctg aatcatagcc tgcctcctct
     1021 aattttgtac tattgtatca aaaactgaca aagtgtcaag gaggaaactg atgaactgga
     1081 caaaaaacaa gcctacatcg tcagctgcca cagtggtttg cgcagctata tcgcagagcc
     1141 tatcctcaag caagcaggat ttaccgccca aaaccttgac ggcgcttatt cactatacaa
     1201 aatggttaac ccagaaggag tagaatatgg aaactagtat cagcatggct gacttttatg
     1261 gaaaatacca aaatgaaaat ctagaactta tcgatgtccg tgaagcacat gaattccaag
     1321 caggacatgc accaggtgcc aaaaatcttc cattaagtac cttagagcaa ggctacaaag
     1381 aactcaaacc tgaccatgaa tactatgtca tttgtcaagg aggagtccgc tctgcatcta
     1441 cctgccagtt tctcagctcc caaggcctca ccgttaccaa cgtagaaggt ggtatgaatg
     1501 cttggcccgg tcaagtagaa taatcaagag gagttgggca aaaactcaat ttcaggaaaa
     1561 gatgaagtaa tactcaatga aaatcaaagt gcaaactagg aagttagccg caggc
//
LOCUS       DAVHTH010000125         1608 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.127, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000125 DAVHTH010000000
VERSION     DAVHTH010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1608)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1608)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1608
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.127"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            complement(<1..1229)
                     /locus_tag="VVR63_002112"
     CDS             complement(<1..1229)
                     /locus_tag="VVR63_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001856522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chordopoxvirus G3 family protein"
                     /protein_id="HEU6130066.1"
                     /translation="MLAEADALVDAEAEALVDAEADALVLVDADVLALVDADVLADVL
                     ALVDADVLAEAEALVLAEAEALVDAEAEALVDADSDAEVLAEADALVLAEADALVDAE
                     AEALVDAEAEALVDAEAEALVDADSDADVLAEADALVDAEADALVLAEADALVLAEAD
                     ALVDADSEALVDAEAEALVDAEAEALVDAEAEALVDAEAEALVDAEAEADVDAEAEAL
                     VDADAEALVLAEADALVDADSDADVLAEAEALVDAEADALIDADSEADVLAEAEALVD
                     AEADALVDAEAEALVLADAEALVDAEADALVDAEADALVDAEADALVDAEAEALVDAE
                     ADALVLAEAEALVDAEADALVDADSDAEVLVLAEAEALVDAEADALVDADSDAEILAE
                     ADALVDAEAEALVLADS"
BASE COUNT          389 a          537 c          365 g          317 t
ORIGIN      
        1 tcagagtcag caagtactag cgcctcagcc tcagcatcaa ccagtgcatc agcctcagca
       61 agtatctcag cgtctgaatc ggcatcaacg agtgcgtcag cctcagcgtc aaccagcgcc
      121 tcagcctcag caagtaccag tacctcagcg tctgaatcgg catcaaccag tgcatcagct
      181 tcagcatcaa cgagtgcttc ggcttcagca agtaccagtg cgtcagcttc cgcatcaaca
      241 agtgcttcag cttccgcatc aacgagtgcg tcggcttccg catcaacgag tgcgtcagct
      301 tccgcatcaa ccagtgcgtc ggcttcagca tcaacaagtg cttcagcatc agcaagtact
      361 agcgcctcag cctcagcgtc aaccagtgcg tcagcttcag cgtcaaccag tgcctcggct
      421 tcagcaagta catcagcttc tgaatctgca tcaataagtg cgtcggcttc agcgtcaacc
      481 agtgcctcgg cttcagcaag cacatcagca tctgaatcag cgtcaaccag tgcgtcggct
      541 tcagcaagca ccagcgcctc agcatccgcg tcaaccagcg cctcggcttc agcatcaacg
      601 tctgcctcag cctcagcatc gacaagtgcc tcggcttcag catcaacgag tgcttcggct
      661 tcagcatcga caagcgcttc agcctcagca tcaaccagtg cttcggcttc agcgtcgaca
      721 agtgcctctg aatcggcatc aaccagtgcg tcagcctcag caagcacaag tgcatcagct
      781 tcagcaagta caagtgcgtc agcctcagca tcgacaagtg cgtcagcttc ggcaagcaca
      841 tcagcatctg aatccgcatc aaccagtgct tcagcttcag cgtcaaccag cgcctcagcc
      901 tcagcatcga caagcgcttc agcttcagca tcaaccagtg cgtcggcttc agcaagcact
      961 agcgcgtcag cctcagcaag cacctcagcg tctgaatcgg catcaacgag cgcctcagct
     1021 tccgcatcaa ccagtgcttc ggcttcagca agtaccagtg cttcggcttc agcaagcacg
     1081 tcagcatcaa caagcgcaag tacatcggca agcacgtcag catcgacaag tgcaagcaca
     1141 tcggcgtcaa caagtactag tgcatcagct tcagcgtcaa cgagtgcttc ggcttccgca
     1201 tcaacaagtg cgtcagcttc agcaagcacc agtgcgtcgg cttcagcatc gacaagtgct
     1261 tcagcttcag cgtcaaccag tgcgtcggct tcagcgtcaa ccagtgcgtc agcctcagca
     1321 agcaccagtg cttcggcttc agcaagtact agcgcctcag cctcagcatc aacaagtgct
     1381 tcagtctcag cgtcaaccag tgcctctgaa tccgcatcaa ccagtgcatc ggcttcagca
     1441 agtactagtg catcagcttc agcatcaacg agtgcttcgg cttcagcaag caccagtgct
     1501 tcggcttcag caagtactag cgcctcagcc tcagcatcaa caagtgcttc agtctcagcg
     1561 tcaaccagtg cctcggcctc agcaagcacc agtgcgtctg aatccgca
//
LOCUS       DAVHTH010000126         1496 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.128, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000126 DAVHTH010000000
VERSION     DAVHTH010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1496)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1496)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1496
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.128"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            144..1340
                     /gene="tuf"
                     /locus_tag="VVR63_002113"
     CDS             144..1340
                     /gene="tuf"
                     /locus_tag="VVR63_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEU6130067.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIVMELMNTVDEYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGIVKVNDEIEIVGIKEETQKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGM
                     VTEIEA"
BASE COUNT          465 a          317 c          304 g          410 t
ORIGIN      
        1 ttaaattttt accaagaata attcacaaaa acgttgtaaa acacttgcaa tttagctgaa
       61 atttgataaa atagtaagga aagttagact gtattgccta ctgtctatct ataaaatata
      121 ttttattgga ggcttttact caaatggcaa aagaaaaata cgatcgtagt aaaccacacg
      181 ttaacattgg tactatcgga cacgttgacc acggtaaaac taccctaact gcagctatca
      241 caactgtttt ggcacgtcgc ttgccttcat cagttaacca acctaaagac tatgcgtcta
      301 tcgatgctgc tccagaagaa cgcgaacgcg gtatcactat caacactgcg cacgttgagt
      361 acgaaactga aaaacgtcac tacgctcaca tcgacgctcc aggacacgcg gactacgtta
      421 aaaacatgat cactggtgct gctcaaatgg acggagctat ccttgtagta gcttcaactg
      481 acggaccaat gccacaaact cgtgagcaca tccttctttc acgtcaggtt ggtgttaaac
      541 accttatcgt cttcatgaac aaagttgact tggttgacga cgaagaattg cttgaattgg
      601 ttgaaatgga aatccgtgac ctattgtcag aatacgactt cccaggtgac gatcttccag
      661 ttatccaagg ttcagcactt aaagctcttg aaggtgactc taaatacgaa gacatcgtta
      721 tggaattgat gaacacagtt gatgagtata tcccagaacc agaacgtgac actgacaaac
      781 cattgcttct tccagtcgag gacgtattct caatcactgg acgtggtaca gttgcttcag
      841 gacgtatcga ccgtggtatc gttaaagtca acgacgaaat cgaaatcgtt ggtatcaaag
      901 aagaaactca aaaagcagtt gttactggtg ttgaaatgtt ccgtaaacaa cttgacgaag
      961 gtcttgctgg agataacgta ggtgtccttc ttcgtggtgt tcaacgtgat gaaatcgaac
     1021 gtggacaagt tatcgctaaa ccaggttcaa tcaacccaca cactaaattc aaaggtgaag
     1081 tctacatcct tactaaagaa gaaggtggac gtcacactcc attcttcaac aactaccgtc
     1141 cacaattcta cttccgtact actgacgtta caggttcaat cgaacttcca gcaggtactg
     1201 aaatggtaat gcctggtgat aacgtgacaa tcgacgttga gttgattcat ccaatcgccg
     1261 tagaacaagg tactacattc tctatccgtg agggtggacg tactgttggt tcaggtatgg
     1321 ttacagaaat cgaagcttaa ttcgatttag ttcccagaag aacaattatt taagtcagac
     1381 actaaaagaa tcttgcttgg caaggttctt ttttggctct ttgtcaactg tagtgggttg
     1441 aaaaaaaact aagctcgaga aaggacaaat ttcgtccttt cttttttgat gttcag
//
LOCUS       DAVHTH010000127         1426 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.129, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000127 DAVHTH010000000
VERSION     DAVHTH010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1426)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1426)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1426
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.129"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            67..447
                     /locus_tag="VVR63_002114"
     CDS             67..447
                     /locus_tag="VVR63_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEU6130068.1"
                     /translation="MIDLYLSKNSRRNQLLLDFFQNYGIEVSCHSVSEMTKDKLIEMM
                     SYSSDCFEFLSPNLLRFKNRDNLRLTDFVEIILKNPELTIRLPLAVSNKRVYPSLNLE
                     EARALLPRDTKQLIYMAQTHYLSN"
     gene            460..603
                     /locus_tag="VVR63_002115"
     CDS             460..603
                     /locus_tag="VVR63_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6130069.1"
                     /translation="MAERFWENLSIILAERNISWIELTRKMFAGEFHYPSELNRLYQK
                     IRH"
     gene            696..1283
                     /locus_tag="VVR63_002116"
     CDS             696..1283
                     /locus_tag="VVR63_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU6130070.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKFLCIGELTILQILYGSSLIS
                     FLWMYGQRKQAHKVNMKSRMKWLGVEFVSLLIISLCFSLIHAQGSTNQANLIGLQHQI
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTSVLFALAHHTGTILAWCLYV
                     SLGMFLGMVRYKSDLWGSMGLHLVWNLLVYSLLLF"
BASE COUNT          441 a          212 c          281 g          492 t
ORIGIN      
        1 caaatttatt agattcctta atcgtctcag aatatcaaat ggaaccgaat ctttgggagg
       61 tctcctatga ttgatctcta tctaagtaaa aatagccgaa gaaatcaact tcttttagac
      121 ttcttccaaa actatggcat cgaggtatct tgtcattcag tttctgaaat gacaaaggac
      181 aaattaattg agatgatgag ctattcttca gattgttttg agtttttatc tcccaattta
      241 ttacgattta agaaccgtga caatctaaga ttaacggatt tcgttgagat aattttaaaa
      301 aatcctgaac taaccatcag acttcctctt gcggtttcaa ataagcgagt ttatccaagt
      361 ctgaatttgg aagaggctag agctctattg ccaagagata cgaaacaatt gatttacatg
      421 gcgcaaacac attatttatc taactaaagg agaagcaata tggctgaacg attttgggag
      481 aacttgtcca ttattttggc tgaaagaaat atcagctgga ttgagttaac cagaaaaatg
      541 tttgcgggag agtttcacta tccaagtgaa ttgaatcgtt tgtatcaaaa gattcgccac
      601 tagaagatgg aacaatgaat gcctcaaagt ccatgggtag aaaggattgt gcaggtatta
      661 gatttagatt atgaagattt atttcggagg taactatgaa aagaataatt ccagtttata
      721 tattccaaca agtaaatgtc ctattggtat ctctatactt attgaaattt ctttgtatcg
      781 gtgagttaac tatactacag attctctatg gttcgtcact catttctttt ttatggatgt
      841 atggccaacg caaacaagcg cataaggtca atatgaaatc taggatgaaa tggcttggtg
      901 ttgaatttgt tagcctactg attataagtc tatgttttag tctgattcat gctcaaggaa
      961 gcacgaatca agcaaactta attggccttc aacatcaaat tccttggttt tcatttttat
     1021 tgttcttaat caatgcgagt atggttgaag aatttctgta tcgagaaatt ttatggaatt
     1081 tggtcagaaa attagatatc agagttgctt tgacaagtgt tttatttgcc ttagcacatc
     1141 atacaggaac cattctagct tggtgtttgt atgtttcact tgggatgttt ttaggtatgg
     1201 tgcgctataa atctgactta tggggcagta tgggactaca tttggtgtgg aacctactag
     1261 tttatagttt gctgcttttt taaaataggt gacctgattt ttaggtaact tctaaaacta
     1321 acttccagtt ttgggagaga gatggaagtt actttgaaaa gttacggaaa cattattttc
     1381 tatgtgacaa cattgtataa ttgcttgcat tttactggtg gagaga
//
LOCUS       DAVHTH010000128         1090 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.130, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000128 DAVHTH010000000
VERSION     DAVHTH010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1090)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1090)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1090
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.130"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            234..833
                     /locus_tag="VVR63_002117"
     CDS             234..833
                     /locus_tag="VVR63_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6130071.1"
                     /translation="MQILCYFTITVVAKPNNSGEVHLDVSIEDNQGGSGHNFSSVSSS
                     SQTAKYEGTGYNNNSSLYITIDKTSDATALLKLKLNNVDNQPATEVPSSGITVKLNAK
                     DNAGNWTSASNKKEVTVKIVSAKPTYPDKILVKNPDNIKDTEKNAIIEKLKEANKNHP
                     AGAPTFAKGEGEHANDIVATYSDGTTYYVPLNDVTKYAR"
     gene            970..1090
                     /locus_tag="VVR63_002118"
                     /pseudo
     CDS             970..1090
                     /locus_tag="VVR63_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-directed DNA polymerase"
BASE COUNT          389 a          162 c          218 g          321 t
ORIGIN      
        1 tatttggaga agaggatggc catcttctcc atttttatgt gcagagttat agtgacttga
       61 tgctgggaaa gtacactgtg actgctaata ctcaatgaaa atcaaagtgc aaactaggaa
      121 gctagccgca ggctgtactt gagtacgtca aggtgaagct gacgtggttt gaatttgatt
      181 ttcgaagagt ataaaacatt cctagaagtt actttgattt ccctaatcta tttatgcaaa
      241 ttttatgtta ttttactata acagttgttg ctaagccaaa taatagtggg gaagttcatt
      301 tagacgtaag cattgaagat aatcagggag gtagtgggca taatttcagt tctgtttcaa
      361 gtagctcaca aacagctaaa tatgaaggaa ctggttataa taacaattca tcattatata
      421 taacgattga taaaacgtct gatgcaacag ctcttttgaa attaaagttg aataatgttg
      481 ataatcaacc tgctactgaa gttcctagtt caggaattac tgtaaaatta aatgctaaag
      541 ataatgctgg aaactggaca agtgcttcga ataaaaaaga agtaacagta aaaattgttt
      601 ctgctaaacc gacatatcca gacaaaatct tagtgaaaaa tcctgataat ataaaagata
      661 cagaaaaaaa tgccattatt gaaaaattga aagaggcaaa taaaaatcat ccagcaggag
      721 ctccaacctt tgctaaaggt gaaggagagc atgcaaatga tattgtagca acttattcag
      781 atggtacaac ttattatgta ccgttaaatg atgtgacaaa atatgcgagg tagtggctgt
      841 accactcact tattcacctc cccgtgattt gtagtagtga taggctttct cactattatt
      901 ataaaacaaa ataaagatca caacactttt tcattctgtg ttgtgccttg agtgaaacga
      961 aaggaatgaa ttataaatat gaaaagtata gtcactagca tagatgagcg cttgcgtact
     1021 cgcctacgag tgattatctg gaagcaatgg aagaagaaat cgagacgatt atggggattg
     1081 cttaagttag
//
LOCUS       DAVHTH010000129         1054 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.131, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000129 DAVHTH010000000
VERSION     DAVHTH010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1054)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1054)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1054
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.131"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            <1..555
                     /locus_tag="VVR63_002119"
     CDS             <1..555
                     /locus_tag="VVR63_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU6130072.1"
                     /translation="KDETTSYPIYEIPEAWRYIKFASLVNFRIGKTPPRSEATFWGTE
                     IPWVSISDMPISGYVTNTRESISKLALKSKKIDISPKGTLLMSFKLSIGKVAILDIPA
                     THNEAIISIFPYANKENIIRDYLMIFLPLISTLGDSKDAIKGKTLNSTSISELLIPIS
                     NHEEMKRIISKVDLLFQKVSQLFE"
     gene            complement(503..1048)
                     /locus_tag="VVR63_002120"
     CDS             complement(503..1048)
                     /locus_tag="VVR63_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001104691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU6130073.1"
                     /translation="MNWVVIKIKDIFSMNTGLSYKKGDLSINNKGVRIIRGGNIKPLE
                     FSLLDNDYYIDTQFISSEQVYLKHNQLITPVSTSLEHIGKFARIDKDYDGVVAGGFIF
                     QLTPFESSEIISKFLLFNLSSPLFYKQLKAITKLSGQALYNIPKTTLSELLIPLAPFE
                     EQELITQKVEKLFEKVNQLWK"
BASE COUNT          380 a          165 c          153 g          356 t
ORIGIN      
        1 aaagacgaaa caacctctta tcctatatat gaaatcccag aagcatggag atatattaaa
       61 tttgctagcc tagttaactt cagaatagga aaaactcctc cacgcagtga agctactttt
      121 tggggaactg aaataccttg ggtatctata tcagatatgc ctatatctgg ttatgtaact
      181 aatacgagag aatctatttc taaattagca ttaaaatcaa agaaaataga catttcacct
      241 aaaggaactt tattaatgag ttttaaatta tctattggaa aagttgccat attggatatt
      301 cctgccactc ataatgaagc cattatatcg atattcccct atgctaataa agaaaatatt
      361 atcagagatt acttaatgat atttttgcca cttatctcta ctttaggtga ttcaaaagat
      421 gctataaaag ggaaaacatt aaatagtacc agtatctccg aattattaat ccctatttct
      481 aatcatgaag agatgaaaag aatcatttcc aaagttgatt tactttttca aaaagtttct
      541 caactttttg agtaataagt tcctgttcct caaaaggagc taacggaatt aatagctcgc
      601 ttagtgtagt tttaggaata ttatataaag cttgacctga tagtttagtt attgctttca
      661 attgtttata aaataacgga gaggacaagt taaataatag aaattttgaa ataatctctg
      721 aactttcgaa tggtgttaat tggaaaataa atccaccagc cacaacacca tcatagtctt
      781 tatcgattct tgcaaacttt ccaatatgtt ctaaagaggt tgatacaggt gttattagct
      841 gattatgttt taaataaact tgttcagagg agatgaattg tgtatcaatg tagtaatcat
      901 tatccaacag agaaaattct aaaggcttaa tattaccacc acgtataatt ctaacacctt
      961 tattattaat gcttaaatcg cccttcttgt aagaaagacc tgtattcatt gaaaaaatat
     1021 cttttatttt tataacaacc caattcatag gtat
//
LOCUS       DAVHTH010000130         1044 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.132, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000130 DAVHTH010000000
VERSION     DAVHTH010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1044)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1044)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1044
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.132"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            complement(743..1003)
                     /locus_tag="VVR63_002121"
     CDS             complement(743..1003)
                     /locus_tag="VVR63_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6130074.1"
                     /translation="MRERSATGAQDLSKSIKKHLNDLTRLTASLLGDEKLSAITSSSA
                     VKADMHRFVIELEPVKSTILQNDDISLDQNEIFEILKNFLDG"
BASE COUNT          350 a          202 c          164 g          328 t
ORIGIN      
        1 tatatgcaca gacatatgaa atctttttga tacatccttc tttttacata gagagacagc
       61 agttatgata tatttatcca tacacaacat cttctgtacc aatactacaa tattggtaca
      121 ttttgattac acaatcgttt caaaaaatat gatggaagcc tgagtatttt atagtaactc
      181 ccttcctatc aactagatca accagttgag tgttgaatgt tgaaacaccc tagcctcagc
      241 aaaggactat gagcagcatt tcctagccaa taggacgctc caaatcacct attctaaatc
      301 catcactagc ttggtcagta agatacagac tgcaaggcaa gactgacgtg gttgatgaga
      361 ttttggaaga gtattacaat catagattca ccagtagact tgaccgcaga tttaactata
      421 gtagattgaa actagaatag tacacctctg cttctaaaac attgttagaa atcgatttga
      481 ctgtcctgat caatttgtcc tgttctcgtt tcattttact atactaaaaa accacctgaa
      541 acaaatcaag tgactagagg ataaaaacaa agactgggca aaaagttttg aaaagcaaaa
      601 aacgcataat atcaggtctt gaaaaacctt gatactatac gtttgattgt gggaagattg
      661 acttcatttt ctcctgaaat tgaagttttt tctagtttcc agatatagac gaattcaata
      721 tagccatctc gctacaatta ttttaaccat cgagaaaatt tttcagaatt tcaaaaattt
      781 cattttgatc caatgaaatg tcatcatttt gaagaatagt tgacttcaca ggctctaatt
      841 ctatcacaaa gcggtgcatg tctgctttta ccgcactact tgatgttata gccgataact
      901 tttcatctcc tagcaaggaa gctgtcaaac gggtaaggtc attcaaatgc tttttaatgg
      961 acttacttaa atcttgagca cctgtagcag agcgctctct catatccagc caagctttag
     1021 ccttaaaaat aattaatact caat
//
LOCUS       DAVHTH010000131          988 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.134, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000131 DAVHTH010000000
VERSION     DAVHTH010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 988)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 988)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..988
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.134"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            complement(1..557)
                     /locus_tag="VVR63_002122"
                     /pseudo
     CDS             complement(1..557)
                     /locus_tag="VVR63_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007897432.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(652..963)
                     /locus_tag="VVR63_002123"
     CDS             complement(652..963)
                     /locus_tag="VVR63_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU6130075.1"
                     /translation="MGLPITRKEISNWHIKTSQYYLEPLYNLLRERLLTQPLLHADET
                     SYRVLESDSQLTYYWTFLSGKAEKQGITLYHHDQCRSGSVVQEFLGDYSGYVHCDILR
                     Q"
BASE COUNT          277 a          235 c          186 g          290 t
ORIGIN      
        1 ggatagatat ttctcgctat ttaattgatg acgtttagct gtttccaaca aactcataat
       61 aatagctctt gctttagctc cttcaaaact ttgagaaaat aaccaccctc gcttttttaa
      121 actgagctta ggctaaaaga gtccactgga ctcttttact ccgtcccata accaatgatt
      181 taatggcgcg ttcagctaga ttattggaaa ggaccagatg tccgtctttc aaaatggtct
      241 taaaggtttc ttcatacttg aggctgtatt caattgccct tcctagtttt gaacctgcta
      301 aaactgactg acgccggcac taagcaaaga agtcttccat taagggctgg agatgttctt
      361 gacgtttctg tagtcgttca tcagctggca aagcctccca gtctctttcc aaggaaaata
      421 actgatcaca ataagctaaa cctttagctc ctaaggatga tttatccgct tgcttggggg
      481 ggcgcttcaa aaaacttcct tctcacatgc gcccaacatc caacaagttc agcttcttcc
      541 agttgacgat aagcagacga gcggttcgaa gtttaccaag cttagcgtcg ccttgctcct
      601 aaaccttgga ctgctatcgc ataggcagaa ctagaggact aaagtcctaa gttactgccg
      661 caaaatatca caatgcacat agccagaata atctcctagg aattcttgta ctactgaacc
      721 acttcgacac tgatcatggt ggtaaagcgt aatcccttgt ttctctgctt tacctgacaa
      781 aaaagtccaa tagtaagtca gctgactatc actctctagc accctataag aagtttcatc
      841 cgcatgaagt aagggctgag tcaatagtct ctctcgcaag aggttataaa ggggctccaa
      901 atagtattga ctcgtcttga tatgccaatt agagatttcc ttacgtgtga ttggtaaacc
      961 catcctagcc caatcttctt cttggcga
//
LOCUS       DAVHTH010000132          857 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.135, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000132 DAVHTH010000000
VERSION     DAVHTH010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 857)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 857)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..857
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.135"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            complement(453..851)
                     /locus_tag="VVR63_002124"
     CDS             complement(453..851)
                     /locus_tag="VVR63_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6130076.1"
                     /translation="MENKESHKSQEIGNLIRVYNRSKREEAESEPLNLYVEDEKGNLL
                     AGLIAETFGNWLEIEYLFVKEELRGQGIGSKLLQQAESEAKNRNCCFAFVNTYQFQAP
                     DFYQKHGYKEVFSLQDYLYIRQRYYYQKNL"
BASE COUNT          243 a          176 c          128 g          310 t
ORIGIN      
        1 tcttgcatct ctgtgccttt cttgtgtttg tggttgaaca acaagtataa cacagaggtg
       61 ttttcttatg cctacaagag ctttcattat ttccattttc ttttggattt cactctattc
      121 tgaaaaactt gtgtatattt actgaagcta gcaagtctta cctgtaaatt taatgaaagc
      181 aacacaaaat ccgagagggg aatctcggat taatagatag agagttttta gtttaaataa
      241 attgtttaaa atatcaacaa catcacttct tttcttaacc tgataagtct tgattcctaa
      301 ttttggggct acgattatat tgtcctcaat atcgtctaga aagacacaat ttctaggtta
      361 taactggtat ttatcgatag ttactcatat acatcagtcc acctccatac ttatgtgcga
      421 gcctctcttt gtattatacc tccatactca ccttacagat tcttttggta ataatatctt
      481 tgcctaatgt agagatagtc ttgcaaagaa aaaacttcct tgtagccatg tttctgataa
      541 aagtccggtg cctggaactg gtaagtattg acaaaggcaa aacaacaatt tcgattctta
      601 gcttcacttt ctgcctgttg caatagtttt gaaccgattc cttgccctcg cagttcctct
      661 tttacaaaca aatactcgat ttctagccaa tttccaaaag tctctgctat caaacctgcc
      721 aggagattgc ccttttcatc ttcgacataa agattaagtg gctcactttc agcctcttct
      781 ctttttgaac ggttataaac acgaatcaga ttccctattt cttgcgattt atgtgattcc
      841 ttattttcca atctaaa
//
LOCUS       DAVHTH010000133          851 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.136, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000133 DAVHTH010000000
VERSION     DAVHTH010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 851)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 851)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..851
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.136"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            complement(1..851)
                     /locus_tag="VVR63_002125"
                     /pseudo
     CDS             complement(1..851)
                     /locus_tag="VVR63_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436408.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
BASE COUNT          259 a          154 c          174 g          264 t
ORIGIN      
        1 aggatgaacc tgcttaagat tgtcctcaat aagtccgaaa aatttctctg gttccttatt
       61 atagagctga tagtggtgtt tcaagtcttc tgaatagctc aaaagcttgt ttaaaatctc
      121 tttattggtt aagtacatac gaaaagtaga acgataaaat cgcttatcac tcagtttacg
      181 gctatcctgt tgaatgagtt tccagtagcg cttgatagcc ttgtattcat gagactttcg
      241 atgaaactga ttcatgattt ggacatgcac acgactcata gcacggctaa gatgttgtac
      301 aatatgaaag cgatcaagaa cgattttagc attcgggagt gaaacagtct gggagactgt
      361 ttcagcctga gcctagaaat ttgaaagcga agttgtctag ctaagtcata gtaaggacta
      421 aacatatcca tagtaatgat tttcacttga caacgaacgg ctctatcata tttaagaaag
      481 tgatctcgga tgatagcttg tgttctacct tcaagaacag tgatgatatt gagcttttca
      541 aaatcttgcg caataaagct catctccatc tcccgattga aacagtcact ccccggactg
      601 tttcaacgtc ccaagacata atctcaggca gatttctaaa attacactca aagtggaagt
      661 cattgagctt tcgaatgaca gttgaagttg agatggaaag ctgatgggca atatcggtca
      721 tagaaatctt ttcaattaac ttttgagcaa tcttttggtt gatgatacga gggatttggt
      781 gattcttctt gacgatagaa gtttcagcga ccatcatttt tgaacagtga tagcacttga
      841 atcgacgctt t
//
LOCUS       DAVHTH010000134          752 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.137, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000134 DAVHTH010000000
VERSION     DAVHTH010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 752)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 752)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..752
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.137"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            82..>752
                     /locus_tag="VVR63_002126"
     CDS             82..>752
                     /locus_tag="VVR63_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HEU6130077.1"
                     /translation="MVSSEFISKIEFACNKKESLYSQSKFKYAIRSMFAGAFLTFSTA
                     AGAVGADLINKIAPGSGRFLFPFVFAWGLAYIVFLNAELVTSNMMFLTAGSLLKKISW
                     RKTAEILLYCTLFNLIGALIAGWGFAHSAAYANLTHDSFISGVVEMKLGRSNELVLLE
                     AILANIFVNIAILSFVLVKDGGAKLWLVLSAIYMFVFLTNEHIAANFASFAIVKFSVA
                     ADSIA"
BASE COUNT          198 a          127 c          163 g          264 t
ORIGIN      
        1 cttttatgaa atatagaaaa cgcttcctaa aacctaaagt ttgtgatata attatcaaga
       61 aaaaagattt aggagtttat tatggtttct tcagaattta tctcaaagat tgaatttgct
      121 tgcaataaga aagaaagtct ttatagtcaa agcaaattta agtatgcgat tcgttcgatg
      181 ttcgcaggtg catttttaac cttcagtact gctgcaggtg cagttggggc tgacttgatt
      241 aataaaattg caccaggtag tggacgcttc ctctttccat tcgtttttgc ttggggcttg
      301 gcctacattg tttttttgaa tgccgagttg gtcacttcaa acatgatgtt cttgactgct
      361 ggtagtttat taaaaaaaat ctcttggaga aaaacagctg agattttact atactgtacc
      421 ttgttcaacc ttatcggagc cttgatagca gggtggggct ttgctcattc ggcagcctat
      481 gcgaatctga cacacgatag tttcatctca ggggttgtag agatgaagtt aggccgctca
      541 aatgaattgg tcttgcttga ggcgattttg gcaaatattt tcgtaaacat tgccattctt
      601 tcatttgttt tggtcaaaga tggtggtgcc aaactttggc ttgtgttgtc agctatttac
      661 atgtttgtat tcttaacaaa cgagcacatt gcggcgaact ttgcttcttt cgcgattgtg
      721 aaattcagtg ttgctgcgga ttcaattgcc aa
//
LOCUS       DAVHTH010000135          729 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.138, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000135 DAVHTH010000000
VERSION     DAVHTH010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 729)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 729)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..729
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.138"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            264..626
                     /locus_tag="VVR63_002127"
     CDS             264..626
                     /locus_tag="VVR63_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6130078.1"
                     /translation="MPKTKTLAELADVILWGFDFANDHAHAFFMDNVEWSHADSYFLS
                     FVSDDVEERYTENVYLDSLSVKQKFKFIFDFGDEWRFECQVLREIETEDEEAYLVRSV
                     GTSPEQYPDYDGFDYEEW"
BASE COUNT          253 a          111 c          152 g          213 t
ORIGIN      
        1 aaaacaagaa caccttgctt ggcgcagggt gtttcgcgtg aaacagaaga attatctggt
       61 ttcaaatgct acagttagac aaacttatga taaaatagca gaaagtgaat gtttcctaag
      121 agcaattcta tcgatgagca attggaggta ttatgctaca cttaaaatta gtaaaacaag
      181 aaatagaagc tgaaaagcca gcatctgtag aagcttggat catttccgtc aaatttaaaa
      241 aaggttgcta ccgacatata tagattccaa aaacaaaaac gttagcggaa ctagcagatg
      301 tgattttatg gggttttgat tttgcaaatg atcatgctca cgcatttttc atggataatg
      361 ttgagtggag tcatgcagat tcttactttc ttagctttgt tagtgacgat gttgaagaac
      421 gttacacaga aaatgtctat ctggatagcc taagtgtcaa acaaaaattt aagtttattt
      481 tcgacttcgg tgatgaatgg cgttttgaat gccaagtact gagagaaatc gagacagagg
      541 acgaagaagc ttatctcgta cgttcggttg gaacgtcgcc agaacaatat ccagattatg
      601 atggttttga ctatgaagaa tggtaaaatt gaaatctaaa aaacaattgg aatcagtctg
      661 tgtaggctta gtatttcaat agacttcctg caaaactaga atcctaattc atgattgata
      721 ataccagca
//
LOCUS       DAVHTH010000136          696 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.139, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000136 DAVHTH010000000
VERSION     DAVHTH010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 696)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 696)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..696
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.139"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            40..>696
                     /locus_tag="VVR63_002128"
     CDS             40..>696
                     /locus_tag="VVR63_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001856457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element IS1167A family transposase"
                     /protein_id="HEU6130079.1"
                     /translation="MEQLHFITKLLDIKDPNIKILDIINMDTHKEIIAKLDYEAPSCP
                     DCGSLMKKYDFQKPSKIPYLETTGMPSRILLRKRRFKCYHCSKMMVAETPLVKKNHQI
                     PRIINQKIAQKLIEKISMTDIAHQLAISTSTVIRKLNDFHFEHDFSRLPKIMSWDEYA
                     FTKGKMSFIAQDFDNLNIITVLEGRTQAVIRNHFLRYDRAVRCQVKIITMDMFSPYYD
                     L"
BASE COUNT          232 a          144 c          114 g          206 t
ORIGIN      
        1 taatgaaaag cgacaaaaca actcattaga aagaatcata tggaacaatt acattttatc
       61 acaaaactgc tcgatattaa agacccaaac atcaagattc tagatatcat caatatggat
      121 acccacaaag aaattatcgc taagctggat tatgaggctc catcttgccc tgattgtgga
      181 agtctaatga agaaatatga ctttcaaaaa ccgtctaaga tcccttacct cgaaacaact
      241 ggtatgcctt ctagaattct ccttagaaaa cgccgtttca agtgctatca ctgttcaaaa
      301 atgatggttg ctgagactcc cctggtaaag aaaaatcacc aaatccctcg tatcatcaac
      361 caaaaaattg ctcaaaagtt aattgaaaaa atttctatga ctgatattgc ccatcagctg
      421 gccatttcaa cttcaactgt cattcgcaag ctcaatgact ttcactttga gcatgatttt
      481 tctcggcttc caaagattat gtcttgggat gagtatgcct tcactaaggg aaagatgagt
      541 ttcattgcgc aagattttga taatcttaat attatcactg ttcttgaagg cagaacacaa
      601 gctgtcatcc gaaatcactt tcttcgctac gatagagccg ttcgttgtca agtgaaaatc
      661 attacgatgg atatgtttag tccttactat gacttg
//
LOCUS       DAVHTH010000137          692 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.140, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000137 DAVHTH010000000
VERSION     DAVHTH010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 692)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 692)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..692
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.140"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            complement(<1..>692)
                     /locus_tag="VVR63_002129"
     CDS             complement(<1..>692)
                     /locus_tag="VVR63_002129"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6130080.1"
                     /translation="LVDADVLADVLVLVDADVLAEAEALVLAEADALVDAEAEALVDA
                     DSDAEVLAEADADALVDAEAEALVLADAEALVDAEAEALVDAEADALVDAEADALVDA
                     EAEALVLADAEALVDAEAEALVLAEADALVDADSDALVEADSDAEVLAEAEALVDAEA
                     DALVDAEAEALVLAEAEADVDADSEADVLAEADALVDAEAEALVLAEADALVDAEADA
                     LVDAEADALVDA"
BASE COUNT          176 a          225 c          158 g          133 t
ORIGIN      
        1 agcgtcaacg agtgcgtcag cttcagcatc aacaagtgca tcagcttcag catcaaccag
       61 tgcatcagcc tcagcaagta ccagcgcctc agcttcagca tcgacaagtg cgtcagcttc
      121 agcaagcaca tcagcttctg aatccgcatc aacgtctgcc tcagcctcag caagtacaag
      181 tgcttcagct tcagcatcaa ccagtgcgtc agcctcagca tcaacgagtg cttcggcttc
      241 agcaagcacc tcagcatctg aatcagcctc aacgagtgcg tctgaatccg catcaacgag
      301 tgcgtcagcc tcagcaagta ccagcgcctc agcctcagca tcaacgagtg cttcggcatc
      361 agcaagtacc agtgcttcag cttcagcgtc aaccagtgcg tcagcttccg catcaacgag
      421 tgcgtcggct tcagcgtcaa ccagtgcctc ggcttccgca tcaacgagtg cttcggcatc
      481 agcaagtaca agtgcctcag cctcagcatc aacgagtgcg tcagcgtcgg cttcagcaag
      541 tacctcagcg tctgaatcgg catcaacgag tgcttcagct tcagcatcaa cgagtgcgtc
      601 agcctcagca agcaccagtg cttcggcttc agcaagcacg tcagcatcaa caagcacaag
      661 tacatcggca agcacgtcag catcgacaag tg
//
LOCUS       DAVHTH010000138          692 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.141, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000138 DAVHTH010000000
VERSION     DAVHTH010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 692)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 692)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..692
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.141"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            complement(74..147)
                     /locus_tag="VVR63_002130"
     tRNA            complement(74..147)
                     /locus_tag="VVR63_002130"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(111..113),aa:Arg,seq:acg)
     gene            complement(157..242)
                     /locus_tag="VVR63_002131"
     tRNA            complement(157..242)
                     /locus_tag="VVR63_002131"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(206..208),aa:Leu,seq:taa)
     gene            complement(250..321)
                     /locus_tag="VVR63_002132"
     tRNA            complement(250..321)
                     /locus_tag="VVR63_002132"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(287..289),aa:Gly,seq:gcc)
     gene            complement(344..416)
                     /locus_tag="VVR63_002133"
     tRNA            complement(344..416)
                     /locus_tag="VVR63_002133"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(381..383),aa:Thr,seq:tgt)
     gene            complement(435..516)
                     /locus_tag="VVR63_002134"
     tRNA            complement(435..516)
                     /locus_tag="VVR63_002134"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(480..482),aa:Leu,seq:tag)
     gene            complement(522..594)
                     /locus_tag="VVR63_002135"
     tRNA            complement(522..594)
                     /locus_tag="VVR63_002135"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(559..561),aa:Lys,seq:ttt)
     gene            complement(619..691)
                     /locus_tag="VVR63_002136"
     tRNA            complement(619..691)
                     /locus_tag="VVR63_002136"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(656..658),aa:Asp,seq:gtc)
BASE COUNT          179 a          205 c          149 g          159 t
ORIGIN      
        1 cgaacctgcg acaccttggt cccaaaccaa gtactctacc aagctgagct acttcccgag
       61 ttaaatagaa aaatgcaccc tagaggagtc gaacctctaa ccgcctgatt cgtagtcagg
      121 tactctatcc agttgagcta agggtgctcc atattatgcc gaggaccgga atcgaaccgg
      181 tacgatcgtt accaatcgca ggattttaag tcctgtgcgt ctgccagttc cgccaccccg
      241 gcctctctaa gcgaacgacg ggattcgaac ccgcgacccc caccttggca aggtggtgtt
      301 ctaccactga actacgttcg cactgttttc ttctatctaa aaatgccggc tacatgactt
      361 gaacacgcga ccctctgatt acaaatcaga tgctctacca actgagctaa gccggctcat
      421 ttgttatatc ttaatgcggg ttaagggact tgaaccccca cgccgttaag cgccagatcc
      481 taaatctggt gcgtctgcca attccgccaa acccgcatat atgacccgta ctgggctcga
      541 accagtgacc cattgattaa aagtcaattg ctctaccaac tgagctaacg agtctaaaat
      601 aacttgcgtt accttaaacg gtcccgacgg gaatcgaacc cgcgatcttc gccgtgacag
      661 ggcgacgtga taaccgctac actacgggac ct
//
LOCUS       DAVHTH010000139          628 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.142, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000139 DAVHTH010000000
VERSION     DAVHTH010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 628)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 628)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..628
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.142"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            <1..>628
                     /locus_tag="VVR63_002137"
     CDS             <1..>628
                     /locus_tag="VVR63_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HEU6130081.1"
                     /translation="DFMQIDLANLLPDLPGNLSGINPNRYVFYQDVLCPILDRHMTPE
                     QDKPHFAQAAGTIADIKEKAGNYAYLFETQAQLNAILSSKVDVGRRIRQAYQADDKES
                     LQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDIRMGGLLQRIKRAESRIE
                     VYLAGQLDRIDELEVEILPFTDFYADKDFAATTANQWHTIATASTIYTT"
BASE COUNT          188 a          152 c          134 g          154 t
ORIGIN      
        1 gattttatgc agattgacct tgccaacctc ttaccagacc taccaggtaa tctcagtggc
       61 atcaatccca accgctatgt cttttatcag gatgttctct gtccgatact tgaccgacac
      121 atgacacctg aacaggacaa gccacacttc gctcaggcgg cgggaactat tgctgacatt
      181 aaagaaaaag ctggaaacta tgcttatctc tttgaaactc aggcccagtt gaatgctatt
      241 ttaagtagca aagtagatgt gggacgacgc attcgtcagg cctaccaagc ggatgataaa
      301 gaaagtttac aacaaatcgc cagacaagaa ttaccagaac ttagaagcca aattgaagac
      361 ttccatgccc tctttagtca ccaatggttg aaagaaaaca aggtctttgg tttggataca
      421 gttgacatcc gtatgggcgg actcttgcaa cgcatcaaac gagcagaaag ccgtatcgag
      481 gtttatctgg ctggccagct tgaccgcatc gacgagctgg aagttgaaat cctaccattt
      541 actgacttct acgcagacaa ggatttcgca gcaactacag ctaaccagtg gcataccatt
      601 gcgacagctt cgacgattta tacgactt
//
LOCUS       DAVHTH010000140          610 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.143, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000140 DAVHTH010000000
VERSION     DAVHTH010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 610)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 610)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..610
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.143"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            82..561
                     /locus_tag="VVR63_002138"
     CDS             82..561
                     /locus_tag="VVR63_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEU6130082.1"
                     /translation="MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISR
                     EEGLVDDIPRLRKYFKTKFRNRILDYIRKQESQKRRYDKEPYEEVGEISHRISEGGLW
                     LDDYYLFHETLRDYRNKQSKEKQEELERVLSNERFRGRQRVLRDLRIVFKEFTIRTH"
BASE COUNT          238 a           77 c          141 g          154 t
ORIGIN      
        1 ggagctaaag ggaacagaat ggagaaaatg gaacaaatgt gttttctaat ctgttagact
       61 gtatctagaa aggggaaaat tatgattaaa gaattgtatg aagaagtcca agggactgtg
      121 tataagtgta gaaatgaata ttaccttcat ttatgggaat tatcggattg ggaccaagaa
      181 ggcatgctct gcttacatga attgattagt agagaagaag gactggtaga cgatattcca
      241 cgtttaagga aatatttcaa aaccaagttt cgaaatcgaa ttttagacta tatccgtaag
      301 caggaaagtc agaagcgtag atacgataaa gaaccctatg aagaagtggg tgagatcagt
      361 catcgtataa gtgagggggg tctctggcta gatgattatt atctctttca tgaaacacta
      421 agagattata gaaacaaaca aagtaaagag aaacaagaag aactagaacg cgtcttaagc
      481 aatgaacgat ttcgagggcg tcaaagagta ttaagagact tacgcattgt gtttaaggag
      541 tttactatcc gtacccacta gtaagtcatg caaaaaaaaa tgaaaaaaat tagaaaaagt
      601 agttgacaaa
//
LOCUS       DAVHTH010000141          606 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.144, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000141 DAVHTH010000000
VERSION     DAVHTH010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 606)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 606)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..606
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.144"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            165..383
                     /locus_tag="VVR63_002139"
     CDS             165..383
                     /locus_tag="VVR63_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001859328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export chaperone SecB"
                     /protein_id="HEU6130083.1"
                     /translation="MKKISVTVIGYFEINIDENITDILYVNGTAILYPYLRSIVSIVS
                     AIDSSEAMLLPTINVLELLDKSQPFEEE"
BASE COUNT          207 a           71 c          111 g          217 t
ORIGIN      
        1 ttttcattga gtataacaca ttgttagaag ttggtttaaa tttcctaatc agtttgttca
       61 catttacctt cgatatatta tatcccatag ttaaggttgg tcatacagat gattatagcc
      121 atggagccgt aaaacttagt gtttctttag ttgacaaaga tgccatgaaa aaaatatctg
      181 taactgtaat aggatatttt gaaataaata tagatgaaaa tatcaccgat attctatacg
      241 taaatggtac tgctattctt tatccttatt tacgttctat tgtttcaata gtttcggcaa
      301 ttgatagcag tgaagcaatg ttgctaccta ccattaatgt tttagagtta ctagataaat
      361 ctcaaccttt tgaagaagaa taatttatta gctcactaaa ttgagggtaa ggaaaagtaa
      421 aagcagtaag aaaaatgtct tgcattatac agcaactttt tgggaatgag tagatggatt
      481 gaataaaatt tgattaagag tggatgattt atctgtagat tattattgga cagttagtct
      541 tgaagtagtc taagaattag gttataatca gtagaagcct tgctaataat gaggaggtta
      601 gtttat
//
LOCUS       DAVHTH010000142          605 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.145, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000142 DAVHTH010000000
VERSION     DAVHTH010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 605)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 605)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..605
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.145"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            67..447
                     /locus_tag="VVR63_002140"
     CDS             67..447
                     /locus_tag="VVR63_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEU6130084.1"
                     /translation="MIDLYLSKNCHRNQLLLDFFQKYGIEVTPHSISEMTKDKLIEMM
                     SYSSDCFEFLSPNLLRFKNRDNLKLTDFIEMILKNPELTIRLPLAVSNKRVYPNLNLE
                     EARALLPRDTKQLIYMAQTHYLSN"
     gene            460..>605
                     /locus_tag="VVR63_002141"
     CDS             460..>605
                     /locus_tag="VVR63_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEU6130085.1"
                     /translation="MAERFWENLSIILAERNISWIELTRKMFAGEFHYPSELNRLYQK
                     IRHY"
BASE COUNT          207 a           99 c          105 g          194 t
ORIGIN      
        1 caaatttatt agattcctta atcgtctcag aatatcaaat ggaaccgaat ctttgggagg
       61 tctcccatga ttgatctcta tctaagtaaa aattgtcata gaaatcaact tcttttggat
      121 ttctttcaaa agtatggcat agaggtcact cctcattcta tttctgaaat gacaaaggat
      181 aaattaattg agatgatgag ctattcttca gattgtttcg agtttttatc tcccaattta
      241 ttacgtttta agaatcgaga taacctaaaa ttaacagatt tcatcgaaat gatattaaaa
      301 aatcctgaac taaccatcag acttcctctt gcggtttcaa ataagcgagt ttatccaaat
      361 ttgaatctgg aggaggctag agctttattg ccaagagata cgaaacaatt gatttacatg
      421 gcacaaacac attatttatc taactaaagg agaatcaata tggcagaacg attttgggag
      481 aacttgtcca ttattttggc tgaaaggaat atcagctgga ttgagttaac cagaaaaatg
      541 tttgcgggag agtttcacta tccaagtgaa ttgaatcgtt tgtatcaaaa gatacgccac
      601 tacaa
//
LOCUS       DAVHTH010000143          553 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.146, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000143 DAVHTH010000000
VERSION     DAVHTH010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 553)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 553)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..553
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.146"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            <1..472
                     /locus_tag="VVR63_002142"
     CDS             <1..472
                     /locus_tag="VVR63_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU6130086.1"
                     /translation="LDYFFDKNLVFCLEADNQEQLFDQVASLLEEREIVTPTYREALI
                     TREKSFPTGLDMEFLGKDLPNVAIPHTDIVHNLAEKVVVVRLEKPVTFHNMIAPDKEV
                     EVSLLFFIINNSSSSQTNILAQLMDFFTGNGHLEDLSKISEPEKLYAYIAEAIA"
BASE COUNT          185 a           95 c          102 g          171 t
ORIGIN      
        1 attagattat ttctttgaca aaaaccttgt gttttgctta gaagcggata atcaagaaca
       61 actctttgat caggtagcaa gcttgttgga agaacgagaa attgtcactc caacttatcg
      121 tgaagccttg atcacgcgtg aaaagtcatt tccaactggt ttagatatgg aatttctagg
      181 aaaggacttg ccaaatgtag cgattcctca cacagatatt gttcataatc tagctgaaaa
      241 agtggtggtt gttcgattag aaaaaccagt aacttttcac aatatgatag ctcctgataa
      301 ggaagtagaa gtatccctac tcttctttat cattaacaat tcaagttcaa gtcaaacaaa
      361 tattctggct cagttgatgg actttttcac aggaaatgga catcttgaag atttatcaaa
      421 aatttccgaa ccagaaaaac tttatgctta cattgctgaa gcaatcgctt aatcttgtct
      481 attaaaaaat aaaatcggag gaaatccaaa tgattaaaat tcttgctgcc tgcggtgagg
      541 tgttaactcg agt
//
LOCUS       DAVHTH010000144          527 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.147, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000144 DAVHTH010000000
VERSION     DAVHTH010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 527)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 527)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..527
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.147"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            complement(1..527)
                     /locus_tag="VVR63_002143"
                     /pseudo
     CDS             complement(1..527)
                     /locus_tag="VVR63_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT          158 a          107 c          101 g          161 t
ORIGIN      
        1 tttaaggtac ttgatttatg ccatatagca ttgtccataa cgagtaaaaa ataatcatct
       61 ggataagctt gtgaaagctc ttctaaaaag acgttcatcc actcagtatt acatccacca
      121 gctattaaga aaaatgattc gcctgtatgg ggcatcaaca gctccataac aatagcgaaa
      181 ttctcgtata tagtgactat ggacatgtgg acctactcct attggagacc aacaagatcc
      241 cagtttactg attctaccga aaccagcctc atcttggtac atcaagcgaa ccttatgaaa
      301 aggtctactg gttttaaagc gctttcttgt cttcttgaat tgagatttta tttttagacg
      361 cgacaatggt ttgagcgtct gctttcttag gatgttctgg acgtggcata atatttcgcc
      421 aaccatggtg cttcaacagt tgatagaagg catcacgtgt gtaggaacga tataagcctg
      481 aaataaggta ttgtaacaaa ttctcctgcc tctgtagcct tcaaatg
//
LOCUS       DAVHTH010000145          498 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.148, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000145 DAVHTH010000000
VERSION     DAVHTH010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 498)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 498)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..498
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.148"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            1..498
                     /locus_tag="VVR63_002144"
                     /pseudo
     CDS             1..498
                     /locus_tag="VVR63_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436408.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          151 a           97 c           95 g          155 t
ORIGIN      
        1 aaaattcctt accttgaaac gactggtatg cctactagaa ttctccttag aaaacgtcgt
       61 tttaagtgct atcattgctt gaaaatgatg gtcgctgaaa cttctatcgt caagaaaaat
      121 caccaaattc ctcgtattat caaccaaaag attgcgcaaa agttaattga aaagatttct
      181 atgaccgata ttgcccatca gctggccatt tcaacttcaa ctgtcattcg aaagctcaat
      241 gacttccact ttgagtgtaa ttttagaaat ctgcctaaga ttatgtcttg ggacgttgaa
      301 acagtccggg gagtgactgt ttcaatcggg agatggagat gagctttatt gcgcaagatt
      361 ttgaaaagct cgatatcatc actgttcttg agggtagaac acaagctgtc atccgagatc
      421 actttcttaa atatgataga gccgtccgat gtcgcgtcaa aattattact atggatatgt
      481 ttagtcctta ctatgact
//
LOCUS       DAVHTH010000146          485 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.149, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000146 DAVHTH010000000
VERSION     DAVHTH010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 485)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.149"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            237..>485
                     /locus_tag="VVR63_002145"
     CDS             237..>485
                     /locus_tag="VVR63_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU6130087.1"
                     /translation="MQEHYTPKGKHLTIDNRRLIERWKNENKSNREIAGLLGKAPQTI
                     HTEVKRGTTLQQVRKGLYKKVYSADYAQTVYQFNRKRSV"
BASE COUNT          169 a           85 c          105 g          126 t
ORIGIN      
        1 ccaccttacc ttagtcaaga attagatgtt tcactatgtt tgagtaagtt gatgatttca
       61 tttgataaca ggtttgaaac tgttaggcta ggtggccaag gctaatcata gccttggttt
      121 agctgaaaaa acaggttcaa gggttcctgt tgtcaaatga aatgtgattt aaggtataag
      181 aaaacacctc tgtgctatac ttgttgttca ccacaaacac aaggaaaggc acagagatgc
      241 aagaacatta taccccaaaa gggaaacatt tgacaataga taaccgtcgc ttgattgagc
      301 ggtggaagaa tgaaaataag tccaatcgtg aaattgcagg cttgttagga aaggcgcctc
      361 aaacgattca tactgaagtc aaaagaggta caactttaca acaagtgaga aaagggctat
      421 acaaaaaggt ctattctgcc gattacgcac aaactgttta ccaattcaat cgaaaacggt
      481 cggtg
//
LOCUS       DAVHTH010000147          485 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.150, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000147 DAVHTH010000000
VERSION     DAVHTH010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 485)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.150"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            complement(<1..167)
                     /locus_tag="VVR63_002146"
     CDS             complement(<1..167)
                     /locus_tag="VVR63_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU6130088.1"
                     /translation="MKSTEEEIQTIKTLLKDFRTAKYHKRLQIVLFRLMGKSYKEIID
                     LLDCNQTTIWR"
BASE COUNT          154 a           75 c           74 g          182 t
ORIGIN      
        1 tttcgccaaa tcgttgtttg attacagtct aaaagatcta taatctcttt ataagatttg
       61 cccatcagac gaaatagaac gatttgaagg cgtttatgat atttagctgt acgaaagtct
      121 tttaaaagtg ttttgatggt ttggatttct tcttcagttg atttcatatt actattgtat
      181 aatgcttttt gatttgagtc tagtattata ctcttcgaaa atctcttcaa accgcgtcag
      241 cttcgccttg tcgtatagat gttactgact tcgtcagttc tatctacaac ctaaaaacag
      301 tgttttgagc agtctgcagc taactttcta taacaaaatg aaataagaac aagacaaatc
      361 aatcaagaca atcaaatcga tttctaacaa tgttttaaaa gtagatgtgt actattctag
      421 tttcaatata ttatagtttg ctctttgatt ttcattgagt attagttcaa tatctaaaaa
      481 aagag
//
LOCUS       DAVHTH010000148          460 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.151, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000148 DAVHTH010000000
VERSION     DAVHTH010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 460)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.151"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            complement(316..>460)
                     /locus_tag="VVR63_002147"
     CDS             complement(316..>460)
                     /locus_tag="VVR63_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000251933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HEU6130089.1"
                     /translation="DEIEKTRRRVNGLEYSIIPNLSETIHYIELKLEEAERANLVRIM
                     KVK"
BASE COUNT          158 a           80 c           61 g          161 t
ORIGIN      
        1 gacgagattg tggaatctct acaggaacaa taggttgtgg cattaaaata tcctccaata
       61 gttttacttt actaatagta tacaggagga gctccatgaa tgatagatac cttgttatga
      121 cgcgcttact ttctatataa ttacatttac gatttactaa tcctaaatct agattagtag
      181 aaacattttc attatctaac aaaccaaaat tttgaaaaag atatcctgat actgtcaata
      241 aaaaaagctt agaaaggctt aaagccttat ccaagctgat atttgttcat ctaattaata
      301 atctaaataa aggatctact tcactttcat aatacgaact aaattggctc tttctgcctc
      361 ctctagtttc aattctatat aatgaatagt ttccgacaag tttggaataa tcgagtattc
      421 taaaccattt acacgtctac gtgttttttc tatttcatca
//
LOCUS       DAVHTH010000149          402 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.152, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000149 DAVHTH010000000
VERSION     DAVHTH010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 402)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 402)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..402
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.152"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            complement(<1..218)
                     /locus_tag="VVR63_002148"
     CDS             complement(<1..218)
                     /locus_tag="VVR63_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU6130090.1"
                     /translation="MAYSIDFRKKVLSYCERTGSITEASHVFQISRNTIYGWLKLKEK
                     TGELNHQVKGTKPRKVDRDRLKNYLTDNP"
     gene            complement(326..399)
                     /locus_tag="VVR63_002149"
     tRNA            complement(326..399)
                     /locus_tag="VVR63_002149"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(363..365),aa:Asn,seq:gtt)
BASE COUNT          120 a           77 c           63 g          142 t
ORIGIN      
        1 ggattgtcag taagatagtt tttaagtcta tctctatcaa cctttcttgg ttttgttcct
       61 tttacttggt ggtttagctc tcctgttttc tcttttagct ttaaccagcc ataaatggta
      121 ttacgtgaga tttggaaaac gtgtgacgct tctgttatac tacctgttcg ctcacaataa
      181 gagagaactt ttttacgaaa atctattgaa tatgccataa aaagattata ccacattgtg
      241 tactattttt ggttcatttt actataacac aaaatagatt attattacat aacaaaaaag
      301 aggtctaaac ctcttaactc aattactccg ccagtaggac tcgaacctac gacatcatga
      361 ttaacagtca tgcgctacta ccaactgagc tatggcggat ta
//
LOCUS       DAVHTH010000150          375 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.154, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000150 DAVHTH010000000
VERSION     DAVHTH010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 375)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 375)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..375
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.154"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
BASE COUNT          128 a           34 c           70 g          143 t
ORIGIN      
        1 tcataacgca taattttctc cttttcgtga aaaaagttaa cgtaattttg aaatgagctt
       61 aataagaggt actatgtagg tagaaaataa agataggaga aaaagtatga ataaaaaaat
      121 attttgtatt ctagtatgta ttatatcatt gattagtcta gctataatct ttccatgggg
      181 ctggtcgata taatgtaagg gagcttgagt tgttagtgga ggataaaatg ttaagagtaa
      241 tagtagttat tcaatcttta gtaataatac tgcttgctgt tgctttatta ttatctcgga
      301 aaaactttga ttcgttaaat gttgttctta taatgatgat cgtatcacaa ttgttgttat
      361 tagtatattt gataa
//
LOCUS       DAVHTH010000151          368 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.155, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000151 DAVHTH010000000
VERSION     DAVHTH010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 368)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 368)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..368
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.155"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            complement(<1..>368)
                     /locus_tag="VVR63_002150"
     CDS             complement(<1..>368)
                     /locus_tag="VVR63_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007897432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU6130091.1"
                     /translation="QLEEAELVGCWVHVRRKFFEATPKQANKSSLGAKGLAYCNQLFS
                     LERNWEALPADERLQKRQEHLQPLMEDFFAWCRRQSVLSGSKLGRAIEYSLKYSLKYK
                     ETFKTILKDGHLVLSNNLAE"
BASE COUNT          100 a           84 c           69 g          115 t
ORIGIN      
        1 ttcagctaga ttattggaaa ggaccagatg tccgtctttc aaaatagtct taaaggtttc
       61 tttatacttg aggctatact tgaggctgta ttcaattgcc cttcctagtt ttgaacccga
      121 taaaactgac tgacgccggc accaagcaaa gaaatcttcc attaggggtt ggagatgttc
      181 ttgacgtttc tgtagtcgtt catcagctgg caaagcctcc cagtttcttt ccaaggaaaa
      241 taactgatta caataagcta aacctttagc tcctaaggat gatttattcg cttgcttggg
      301 ggtcgcttca aaaaacttcc ttctcacatg tacccaacat ccaacaagtt cagcttcttc
      361 cagttgac
//
LOCUS       DAVHTH010000152          360 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.156, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000152 DAVHTH010000000
VERSION     DAVHTH010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 360)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 360)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..360
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.156"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            <1..>360
                     /locus_tag="VVR63_002151"
     CDS             <1..>360
                     /locus_tag="VVR63_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEU6130092.1"
                     /translation="KFSPEMMVNKKQVKVGISTIYYWFHNGHLGLTKADMLYPRKRKG
                     VKKQASPNFKPAGKSIEERPDVINLRLENGHYEIDTVLLTKIKNYCLLVLTDRRSRHQ
                     IIRLIPNKTAESVNQAL"
BASE COUNT          123 a           67 c           73 g           97 t
ORIGIN      
        1 aaaaattttc gcctgaaatg atggttaaca agaagcaagt gaaagttggt atttcaacca
       61 tctactactg gtttcataat ggtcatttag gattgacgaa ggccgacatg ctttatccca
      121 gaaaaaggaa aggtgtcaag aagcaagcta gtccgaactt taagccggca ggtaaatcta
      181 tcgaagaacg tcctgacgtt attaatcttc gcttggaaaa tggtcattat gaaattgata
      241 ccgtcctact gactaagata aaaaattatt gcctgttagt cttaaccgac cggcggagca
      301 gacaccaaat tataaggtta attccaaata aaactgctga atctgtcaat caggcgctta
//
LOCUS       DAVHTH010000153          358 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.157, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000153 DAVHTH010000000
VERSION     DAVHTH010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 358)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 358)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..358
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.157"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            <1..234
                     /locus_tag="VVR63_002152"
     CDS             <1..234
                     /locus_tag="VVR63_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU6130093.1"
                     /translation="KVVVVRLEKPVTFHNMIAPDKEVEVSLLFFIINNSSSSQTNILA
                     QLMDFFTGNGHLEDLSKISEPEKLYAYIAEATA"
     gene            272..>358
                     /locus_tag="VVR63_002153"
     CDS             272..>358
                     /locus_tag="VVR63_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HEU6130094.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNR"
BASE COUNT          126 a           65 c           61 g          106 t
ORIGIN      
        1 aaagtggtgg ttgttcgatt agaaaaacca gtaacttttc acaatatgat agctcctgat
       61 aaggaagtag aagtatctct actcttcttt atcattaaca attcaagttc aagtcaaacg
      121 aacattctgg ctcagttgat ggactttttc acaggaaatg gtcatcttga agacctatca
      181 aaaatttctg aaccagaaaa actttatgct tacattgctg aagcaaccgc ttaatcttgt
      241 ctattaaaaa ataaaatcgg aggaaatcca aatgattaaa attcttgctg cctgcggtgc
      301 aggtgttaac tcaagtcacc aaattaaaag tgctctagaa gaagaacttt caaaccgt
//
LOCUS       DAVHTH010000154          355 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.denovo.158, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000154 DAVHTH010000000
VERSION     DAVHTH010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 355)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 355)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..355
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.denovo.158"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            complement(197..284)
                     /locus_tag="VVR63_002154"
     tRNA            complement(197..284)
                     /locus_tag="VVR63_002154"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(248..250),aa:Ser,seq:gct)
BASE COUNT          111 a           87 c           64 g           93 t
ORIGIN      
        1 ggttttcgga actttgaaaa cttcaaaaaa cggattttca tcgctctgaa catcaaaaaa
       61 gaaaggacga aatttgtcct ttctcgagct tagcttttct tcaacccact acagttgaca
      121 aagagcctta agtttacgga tctgaagttt tattgtctct aaaaacaaaa aagagagtta
      181 caaactctca ttaaaacgga gaataaggga ttcgaaccct tgcgccagtt acccgaccta
      241 acgatttagc aaaccgtcct cttcagcctc ttgagtaatt ctccaattaa tgggcacgag
      301 tggactcgaa ccaccgacct cacgcttatc aggcgtgcgc tctaaccacc tgagc
//
LOCUS       DAVHTH010000155         3753 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.guided.100, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000155 DAVHTH010000000
VERSION     DAVHTH010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3753)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3753)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3753
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.guided.100"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            <1..380
                     /locus_tag="VVR63_002155"
     CDS             <1..380
                     /locus_tag="VVR63_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HEU6130095.1"
                     /translation="DDTVQAIMDEALKYEGWRYVYGGASPTTSFDCSGLTQWTYGKAG
                     INLPRTAQQQYDVTQHIPLSEAQAGDLVFFHSTYNAGSYITHVGIYLGNNRMFHAGDP
                     IGYADLTSPYWQQHLVGAGRIKQ"
     gene            377..1309
                     /locus_tag="VVR63_002156"
     CDS             377..1309
                     /locus_tag="VVR63_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEU6130096.1"
                     /translation="MRKEDLMMKFRKNQNKEKQIPKEKKPRVYKVNPHKKVVIALWVL
                     LGLSFSFAIFKHFTAIDTHTIHETTIIEKEYVDTHHVENFVENFAKVYYSWEQSDKSI
                     DNRMESLKGYLTDELQALNVDTVRKDIPVSSSVRGFQIWTVEPTGDNEFNVTYSVDQL
                     ITEGENTKTVHSAYIVSVYVDGSGNMVLVKNPTITNIPKKSSYKPKAIESEGTVDSIT
                     TNEINEFLTTFFKLYPTATASELSYYVNDGILKPIGKEYIFQELVNPIHNRKDNQVTV
                     SLTVEYIDQQTKATQVSQFDLVLEKNGSNWKIIE"
     gene            1554..1670
                     /locus_tag="VVR63_002157"
     CDS             1554..1670
                     /locus_tag="VVR63_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HEU6130097.1"
                     /translation="MILKYPENICMLCMPMVMHKNPSDKSIYHWDFYALLGF"
     gene            1686..3595
                     /gene="tet(M)"
                     /locus_tag="VVR63_002158"
                     /pseudo
     CDS             1686..3595
                     /gene="tet(M)"
                     /locus_tag="VVR63_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
     gene            3693..>3753
                     /locus_tag="VVR63_002159"
     CDS             3693..>3753
                     /locus_tag="VVR63_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012962334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEU6130098.1"
                     /translation="MINYKWILCPVCGNKTRLKI"
BASE COUNT         1268 a          613 c          772 g         1100 t
ORIGIN      
        1 atgatgatac ggtacaagcc atcatggacg aagcactgaa atatgagggc tggcgatacg
       61 tttacggtgg agcttccccg actacttctt ttgattgtag cggactgaca caatggacgt
      121 atggaaaagc tggaattaac ttaccacgaa ccgcacaaca gcaatatgat gtgacccagc
      181 atatcccact atcggaagca caagctggcg atttggtttt ctttcattct acctataacg
      241 ctggctctta tattactcat gttgggatat accttggcaa taaccgtatg tttcatgcag
      301 gcgacccaat cggttatgcc gacttaacaa gcccctactg gcaacagcat ttagtgggag
      361 caggacgaat caaacaatga gaaaggaaga tttaatgatg aaatttagaa aaaatcagaa
      421 taaagaaaaa cagataccaa aggaaaagaa acctcgtgtc tataaggtca atcctcataa
      481 aaaggttgtg attgccttgt gggtactttt agggcttagt ttcagctttg cgatattcaa
      541 gcactttaca gctatagata ctcatactat tcacgaaaca actatcatag aaaaggaata
      601 cgttgatact catcatgtag aaaattttgt agagaacttt gcgaaagtct actattcatg
      661 ggagcaatcc gataagtcca ttgataatcg aatggaaagt ctaaaaggct atctgacaga
      721 tgaacttcaa gctctcaatg ttgatacagt acgcaaagat attcctgtat cgtcttctgt
      781 aagaggattt cagatatgga cggtagagcc aactggcgac aatgagttta atgtaaccta
      841 cagtgtagac cagctcatta cagagggaga aaatacaaag accgtccact ctgcttatat
      901 agtgagtgtc tatgtagatg gttctggaaa tatggtactg gttaagaatc cgaccattac
      961 caacatacct aagaaatcaa gttataaacc aaaagccatt gaaagtgagg ggacggttga
     1021 ttccattaca accaatgaaa tcaatgagtt tttaacgacg ttcttcaagc tctatcctac
     1081 agcgacagcc agtgaacttt cctactatgt gaatgacggg atattaaaac caatcggaaa
     1141 agagtacatc tttcaagaac tggtaaatcc tattcacaat cgtaaggata atcaagtcac
     1201 ggtatcgctg acagtggagt atatcgacca gcagaccaaa gcaacgcagg tatctcaatt
     1261 tgatttggta cttgaaaaga acgggagtaa ttggaagatt atagaataac aaatattggt
     1321 acattattac agctattttg taatcacgta ctctctttga taaaaaattg gagattcctt
     1381 tacaaatatg ctcttatgtg ctattattta agtatctatt taaaaggagt taataaatat
     1441 gcggcaaggt attcttaaat aaactgtcaa tttgatagtg ggaacaaata attggatgtc
     1501 cttttttagg agggcttagt tttttgtacc cagtttaaga atacctttat catgtgattc
     1561 taaagtatcc ggagaatatc tgtatgcttt gtatgcctat ggttatgcat aaaaatccca
     1621 gtgataagag tatttatcac tgggattttt atgccctttt gggtttttga atggaggaaa
     1681 atcacatgaa aattattaat attggagttt tagctcatgt tgatgcagga aaaactacct
     1741 taacagaaag cttattatat aacagtggag cgattacaga attaggaagc gtggacaaag
     1801 gtacaacgag gacggataat acgcttttag aacgtcagag aggaattaca attcagacag
     1861 gaataacctc ttttcagtgg gaaaatacga aggtgaacat catagacacg ccaggacata
     1921 tggatttctt agcagaagta tatcgttcat tatcagtttt agatggggca attctactga
     1981 tttctgcaaa agatggcgta caagcacaaa ctcgtatatt atttcatgca cttaggaaaa
     2041 tggggattcc cacaatcttt tttatcaata agattgacca aaatggaatt gatttatcaa
     2101 cggtttatca ggatattaaa gagaaacttt ctgccgaaat tgtaatcaaa cagaaggtag
     2161 aactgtatcc taatatgtgt gtgacgaact ttaccgaatc tgaacaatgg gatacggtaa
     2221 tagagggaaa cgatgacctt ttagagaaat atatgtccgg taaatcatta gaagcattgg
     2281 aactcgaaca agaggaaagc ataattgttc tctgttccct ctttatcatg gaagtgcaaa
     2341 aagtaatata gggattgata accttataga agtgattacg aataaatttt attcatcaac
     2401 acatcgaggt cagtctgaac tttgcggaaa agttttcaaa attgagtatt cggaaaaaag
     2461 acagcgtctt gcatatatac gtctttatag tggcgtactg catttgcgag attcggttag
     2521 aatatcggaa aaggaaaaaa taaaaattac agaaatgtat acttcaataa atggtgaatt
     2581 atgtaaaatc gataaggctt attccgggga aattgttatt ttgcagaatg agtttttgaa
     2641 gttaaatagt gttcttggag atacaaagct attgccacag agagagagaa ttgaaaatcc
     2701 cctccctctg ctgcaaacga ctgttgaacc gagcaaacct caacaaaggg aaatgttact
     2761 tgatgcactt ttagaaatct ccgacagtga cccgcttctg cgatattatg tggattctgc
     2821 gacacatgaa atcatacttt ctttcttagg gaaagtacaa atggaagtga cttgtgctct
     2881 gctgcaagaa aagtatcatg tggagataga aataaaagag cctacagtca tttatatgga
     2941 aagaccgtta aaaaaagcag agtataccat tcacatcgaa gttccaccga atcctttctg
     3001 ggcttccatt ggtctatctg tagcacagct tccattaggg agcggagtac agtatgagag
     3061 ctcggtttct cttggatact taaatcaatc gtttcaaaat gcagttatgg aggggatacg
     3121 ctatggctgt gaacaaggat tgtatggttg gaatgtgacg gactgtaaaa tctgttttaa
     3181 gtatggctta tactatagcc ctgttagtac cccagcagat tttcggatgc ttgctcctat
     3241 tgtattggaa caagtcttaa aaaaagctgg aacagaattg ttagagccat atcttagttt
     3301 taaaatttat gcgccacagg aatatctttc acgagcatac aacgatgctc ctaaatattg
     3361 tgcgaacatc gtagacactc aattgaaaaa taatgaggtc attcttagtg gagaaatccc
     3421 tgctcggtgt attcaagaat atcgtagtga tttaactttc tttacaaatg gacgtagtgt
     3481 ttgtttaaca gagttaaaag ggtaccatgt tactaccggt gaacctgttt gccagccccg
     3541 tcgtccaaat agtcggatag ataaagtacg atatatgttc aataaaataa cttagtgtat
     3601 tttatgttgt tatataaata tggtttcttg ttaaataaga tgaaatattt tttaataaag
     3661 atttgaatta aagtgtaaag gaggagatag ttattataaa ctacaagtgg atattgtgtc
     3721 ctgtatgtgg aaataaaaca cgattaaaga taa
//
LOCUS       DAVHTH010000156         1855 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.guided.123, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000156 DAVHTH010000000
VERSION     DAVHTH010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1855)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1855)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1855
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.guided.123"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            <1..222
                     /locus_tag="VVR63_002160"
     CDS             <1..222
                     /locus_tag="VVR63_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000214003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6130099.1"
                     /translation="LDDNDPVIIIITRSYNKWYDAIPQLKEYKNCYETSNPSNPSLKP
                     ENLLKVKRYSAKKEVEKVLEDSLKKLEHK"
     gene            461..709
                     /locus_tag="VVR63_002161"
     CDS             461..709
                     /locus_tag="VVR63_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6130100.1"
                     /translation="MNYQKLNDITGATKNEKDKYYVYGLYEEGKQLPFYIGKGEGTRL
                     ISHIDEALTEINQEENIQISKKIQIIRKHKGKIIPVII"
     gene            880..1599
                     /gene="catA"
                     /locus_tag="VVR63_002162"
                     /pseudo
     CDS             880..1599
                     /gene="catA"
                     /locus_tag="VVR63_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032488880.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type A chloramphenicol O-acetyltransferase"
BASE COUNT          672 a          270 c          288 g          625 t
ORIGIN      
        1 ttggatgaca atgatcctgt aatcattatc atcacacgat cttacaataa gtggtacgat
       61 gcaattcctc aattaaaaga gtataaaaat tgttatgaaa cgagtaatcc tagtaatcct
      121 tctttaaaac ctgagaattt attaaaagtc aaacgatatt ctgctaaaaa agaggttgaa
      181 aaagtattag aagattcatt gaaaaagcta gagcataaat aaaacagtct ctttttaatg
      241 ctatcgtaaa tactgtattg tgtagttatt agtaaaccta tatattgtcc ccaaatttat
      301 ttagattatt ctctaggatt ttacttgatt ttaaagaaaa tatagtttaa catataaata
      361 gttcagaatc agaatgaagg tagaataaga ggattatttt aattaatttt taatagtatg
      421 gagcagaact tttataatat atttaaatag gagtaaaaaa atgaattatc aaaaattaaa
      481 tgatattact ggtgctacca aaaatgaaaa agataaatac tatgtttacg gactctatga
      541 agaaggtaag caactacctt tctatattgg taaaggagag ggaactcgcc taatatcaca
      601 tatcgatgaa gcgcttacag agataaatca agaagaaaac atacaaatta gtaaaaaaat
      661 tcaaattatt agaaaacata agggcaaaat tatacctgta atcatttaaa gcacccatta
      721 gttcaacaaa cgaaaattgg ataaagtggg atatttttaa aatatatata tttatgttac
      781 agtaatattg acttttaaaa aaggattgat tctaatgaag aaagcagaca agtaagcctc
      841 ctaaattcac tttagataaa aatttaggag gcatatcaaa tgaactttaa taaaattgat
      901 ttagacaatt ggaagagaaa agagatattt aatcattatt tgaaccaaca aacgactttt
      961 agtataacca cagaaattga tattagtgtt ttataccgaa acataaaaca agaaggatat
     1021 aaattttacc ctgcatttat tttcttagtg acaagggtga taaactcaaa tacagctttt
     1081 agaactggtt acaatagcga cggagagtta ggttattggg ataagttaga gccactttat
     1141 acaatttttg atggtgtatc taaaacattc tctggtattt ggactcctgt aaagaatgac
     1201 ttcaaagagt tttatgattt atacctttct gatgtagaga aatataatgg ttcggggaaa
     1261 ttgtttccca aaacacctat acctgaaaat gctttttctc tttctattat tccatggact
     1321 tcatttactg ggtttaactt aaatatcaat aataatagta attaccttct acccattatt
     1381 acagcaggaa aattcattaa taaaggtaat tcaatatatt taccgctatc tttacaggta
     1441 catcattctg tttgtgatgg ttatcatgca ggattgttta tgaactctat tcaggaattg
     1501 tcagataggc ctaatgactg gcttttataa tatgagataa tgccgactgt actttttaca
     1561 gtcggttttc taatgtcact aacctgcccc gttagttgaa gaaggttttt atattacagc
     1621 tccagatcca tatccttctt tttctgaacc gacttctcct ttttcgcttc tttattccaa
     1681 ttgctttatt gacgttgagc ctcggaaccc ttaacaatcc caaaacttgt cgaatggtcg
     1741 gcttaatagc tcacgctatg ccgacattcg tctgcaagtt tagttaaggg ttcttctcaa
     1801 cgcacaataa attttctcgg cataaatgcg tggtctaatt tttattttta ataac
//
LOCUS       DAVHTH010000157          999 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254676-rid19264833.guided.133, whole
            genome shotgun sequence.
ACCESSION   DAVHTH010000157 DAVHTH010000000
VERSION     DAVHTH010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254676
            Sequence Read Archive: SRR2912527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 999)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 999)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866592.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866592.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:55:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,129
            Genes (coding)                    :: 2,032
            CDSs (with protein)               :: 2,032
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 56 of 97
            Pseudo Genes (incomplete)         :: 42 of 97
            Pseudo Genes (internal stop)      :: 25 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..999
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254676-rid19264833.guided.133"
                     /strain="Streptococcus species"
                     /serotype="23F"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2007-03-18"
                     /collected_by="Catrin Moore"
     gene            100..837
                     /gene="erm(B)"
                     /locus_tag="VVR63_002163"
     CDS             100..837
                     /gene="erm(B)"
                     /locus_tag="VVR63_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HEU6130101.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESRASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTITYEQVLSIFNSYLLFNGRK"
BASE COUNT          369 a          174 c          160 g          296 t
ORIGIN      
        1 gactaatctt atgacttttt aaacagataa ctaaaattac aaacaaatcg tttaacttct
       61 gtatttgttt atagatgtaa tcacttcagg agagattaca tgaacaaaaa tataaaatat
      121 tctcaaaact ttttaacgag tgaaaaagta ctcaaccaaa taataaaaca attgaattta
      181 aaagaaaccg ataccgttta cgaaattgga acaggtaaag ggcatttaac gacgaaactg
      241 gctaaaataa gtaaacaggt aacgtctatt gaattagaca gtcatctatt caacttatcg
      301 tcagaaaaat taaaactgaa tactcgtgtc actttaattc accaagatat tctacagttt
      361 caattcccta acaaacagag gtataaaatt gttgggaata ttccttacca tttaagcaca
      421 caaattatta aaaaagtggt ttttgaaagc cgtgcgtctg acatctatct gattgttgaa
      481 gaaggattct acaagcgtac cttggatatt caccgaacac tagggttgct cttgcacact
      541 caagtctcga ttcagcaatt gcttaagctg ccagcggaat gctttcatcc taaaccaaaa
      601 gtaaacagtg tcttaataaa acttacccgc cataccacag atgttccaga taaatattgg
      661 aagctatata cgtactttgt ttcaaaatgg gtcaatcgag aatatcgtca actgtttact
      721 aaaaatcagt ttcatcaagc aatgaaacac gccaaagtaa acaatttaag taccattact
      781 tatgagcaag tattgtctat ttttaatagt tatctattat ttaacgggag gaaataattc
      841 tatgagtcgc ttttttaaat ttggaaagtt acacgttact aaagggaatg gagataaatt
      901 attagatata ctactgacag cttccaagaa gctaaagagg tccctagcgc ctacggggaa
      961 tttgtatcga taaggggtac aaattcccac taagcgctc
//
